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Today's excellent Wall Street Journal editorial reminds me of a point I overlooked in writing about the absurd United Nations nonmember observer state Palestine. It represents another broken promise:
In effect, the General Assembly voted to violate the 1993 Oslo Accords, which are the legal basis for Mr. Abbas's Palestinian Authority and require negotiations with Israel to create a state. When the world next asks Jerusalem to take "risks for peace," Israelis will know that countries such as France (which voted for the resolution) and Germany (which abstained) will not have their backs.
To paraphrase the great Who song, as surely someone must have done before me: meet the new Abbas, same as the old Abbas.


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General News
: Local News
Eagle River library presents new design
Submitted: 06/18/2013
Eagle River
- You can put songs, books and even movies on a device smaller than your hand.With that kind of technology, you wouldn't think real, brick-and-mortar libraries would be as busy or need as much space. But in Eagle River, the Olson Library is busier than ever.The library's foundation started planning for expansion in 2007. It held an open house to begin its next step in fundraising Tuesday. The group presented a 3-D model to the audience. Nan Andrews has been using the library for three decades. She says these days, the library feels too tight. "There is not enough room for it, Andrews said. "It feels real crunchy and just too tight, not enough space to enjoy yourself."The library sees about 30 percent more traffic compared to eight years ago. The new design would double the size of the library. Raymond Quicksilver thinks the project will impact the community."When you have a project like this and people can identify and be personable with it, things happen, Quicksilver said. "That is how people integrate and thats how things get done.The library has raised about $800,000 so far. They still need $1.4 million to start building.The group hopes to reach their goal in the next few years.
Written By: Adam Fox
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Lip balm for extra moisturizing? Check. Lactaid to help digest the occasional sweet? Check. Pocket mirror to ensure the pearly whites remain food-free? Check. Smartphone because you never know when an inspirational tweet will pop up? Check.
Judy Blume has logged a tremendous number of miles in the last two years in her quest to see her 1981 novel, "Tiger Eyes," turned into a feature film, and the petite yet peppy grandmother is now powering through the final leg of her journey with the well-stocked purse of a road warrior. Though Blume has sold more than 80 million books since her first was published nearly 45 years ago, she knows the $2-million movie "Tiger Eyes," about grief told through the eyes of a teenager from the cliffs of New Mexico, needs all the help it can get.
With no big studio behind the movie, it's up to Blume and her son, Lawrence, who directed the film, to get the word out to her legion of followers. They must reach both the "nostalgia readers," who found adolescence a little less painful with Blume and her characters by their side, and a new crop of fans who are connecting to tales like "Superfudge" and "Tales of a Fourth Grade Nothing" with equal enthusiasm — though many weren't even born when the books were written.
On this trip in late May, Blume has already donned a set of floral pajamas for an afternoon taping of Chelsea Handler's talk show (the comedian titled her second book, "Are You There, Vodka? It's Me, Chelsea," in a twisted homage to the author).
After a midday interview at Shutters in Santa Monica, Blume will head to CineFamily's Silent Movie Theatre on Fairfax, where devotees including writer-actress Nia Vardalos, singer Michelle Branch, "The Office's" Kate Flannery and others will be on hand for a screening of "Tiger Eyes" and a celebration for the author.
"It's been tough. There's no studio. No money. No budget for marketing," admitted Blume, who co-produced and co-wrote the movie with her son. "Do I want to go on TV? Not really. It doesn't look so bad, I guess. I think it's good to tell people about the movie. Maybe the story [audiences] love is that I'm 75 and I still walk and talk."
Blume does a lot more than that. She's writing her 29th book. She continues to mentor writers including Rachel Vail, Carolyn Mackler and Kristen-Paige Madonia. And she is an avid social media user (@judyblume), tweeting daily musings often to her more than 90,000 followers, including Patton Oswalt, Judd Apatow and Zooey Deschanel. (Sample tweet from her recent trip to LA: "What!? They have Magnolia bakery in L.A.? Who knew? Even though I gave up cupcakes a year ago I had to stop in for old time's sake.")
Despite the march of time and technology, Blume's novels remain invaluable blueprints to surviving the trials of teenagedom: everything from understanding bullying ("Blubber") to menstruation ("Are You There God? It's Me, Margaret") to healthful, consensual sex ("Forever").
"We had a wonderful screening in New York recently," said Blume. "Afterwards, Larry and I do our dog-and-pony show, and one woman after another stood up. 'I'm 34.' 'I'm 44.' Then one young lady stood up and said, 'I'm 13, and this is my favorite book.'"
In an era when Hollywood is optioning children's novels for adaptation at a record pace, though, perhaps the most frequent query Blume gets on the publicity trail is: "What took you so long to finally make a movie?"
Open to adaptations
Eating lunch with Judy Blume is like ordering a meal with Meg Ryan's character from "When Harry Met Sally," minus the fake orgasm.
The author, whose narrow frame belies her great capacity for emotion and empathy, settles on a chicken Caesar salad "her way," which once dissected means no garlic croutons, no dressing, just lettuce, Parmesan cheese, olive oil and lemon. She sniffs the oil to make sure no canola has slipped in. (She's allergic.)
Blume, who saw her 1975 book "Forever" turned into a TV movie and previously partnered with her son on an ABC adaptation of "Otherwise Known as Sheila the Great," insisted that she has a cavalier attitude toward her work and would eagerly allow another of her books to be adapted into a film, even without her involvement, should the opportunity come her way. She's particularly keen to see "Starring Sally J. Freedman as Herself" — a story about an imaginative fifth-grader living in Miami Beach in 1947 — on the big screen and onstage.
"I'm open," said Blume. "I think 'Wifey' should be a movie. I don't need to write it. I don't need to be involved in it. And I'm on a big 'Sally Freedman' kick right now because what I want really deep inside is a musical — a Broadway-type musical based on 'Sally Freedman.' And I know just how to do it."
But the fastidiousness that Blume displays over lunch clearly carried over to the making of "Tiger Eyes." Even though she said she's proud of the finished product, she has some criticisms of the PG-13 drama, filmed over just 22 days in Los Alamos, N.M., in fall 2010: Her favorite scene in the book, she says, doesn't resonate nearly as well on the screen: She wishes her heroine, Davey, was dressed in a different color tone for a climactic moment in the film, and even though she insisted on appearing in a cameo, it's a decision she regrets, concerned that her presence takes the audience out of the movie.
"[My scene] leads up to a really important moment in the movie, so I'm kind of sorry," she said. "If people know me, it really ruins the screening. I think I shouldn't have done it."
Blume and her son, Lawrence, were both resolute that "Tiger Eyes" would be the first adaptation when Amber Entertainment came to them with financing from British retailer Tesco. It may not be the most well known of Blume's novels, but to her it's the most cinematic — and one of the most personal to both her and her son. Lawrence experienced a similar fish-out-of-water feeling as Davey when Blume moved him and his older sister to Los Alamos with her second husband, a physicist. The film also captures much of the grief Blume felt at age 21, when her father died just weeks before her wedding to her first husband, John Blume.
"It was such a terrible time and such an awful way to start out: feeling guilty, leaving my mother," she said of her father's death. "But if I had not had to get married then I think what would have happened to me. My mother was needy."
Blume loved her time filming in New Mexico; even revisiting the epicenter of her brief, unhappy second marriage couldn't quell her enthusiasm for the moviemaking. "It made me think, 'If only I were younger, I would do this again,'" she said.
The one bad day, she said, , came when her son was letting the film's lead actors, Willa Holland and Tatanka Means, improvise a quiet scene. It wasn't going well, and Blume was frustrated.
She said she got angry, and "I marched down the hall. I told Larry, 'Just have them say it the way I wrote it,'" she recalled with a laugh. "And they do. Otherwise we were really, really nice to each other."
After the CineFamily screening, Blume mused about whether it's her own attachment to her books that has prevented her work from hitting the big screen. "I'm not like that about letting go, am I?" she asked her son in front of the audience. "No," Lawrence quickly responded, then followed it up with a laugh.
Blume continued, "A book is a book. A movie is a movie. They are made to be different."
To her son, Blume was never an author who sought out Hollywood.
"She did not aggressively market herself as someone who wanted her books turned into movies as soon as possible," he said later by phone. "But also, the producers and studio executives who would come and be interested in doing something didn't come with a specific idea — exactly which book, or how they wanted to treat it. There were a series of near misses over the years. I always thought it was peculiar myself."
A puzzling talent
Blume started writing when she was 25, married with two young children, and wishing for a less scripted life.
"What I longed for was that time of life when everything is ahead of you," she said. "When you are on the brink and it's new and exciting and anything is possible."
The early books, like "Are You There God? It's Me, Margaret," just poured out of her — "It was easier when I didn't know what I was doing," she said — while the latter ones became much more challenging to complete. She spent three years writing 20 drafts of 1998's "Summer Sisters," for instance, and vowed to never write again after it was finished.
Despite her success, Blume struggles to explain why her stories have affected such a wide swath of readers. "I don't know what I do," she said. "I don't know how I did it, and I don't understand it."
Many others have articulated for Blume what makes her literature stand out. In a New Yorker essay on the author in 2012, Anna Holmes wrote, "What Blume is celebrating is that brief yet exhilarating time in a young girl's life in which internal narratives take precedence over external attributes."
Blume grew up in the 1950s in Elizabeth, N.J., with an older brother during a time when parents hid the world's scary truths from their children. Her mother was a homemaker. Her father a dentist. And the degree she was earning at NYU in education was, in her mother's words, a fallback, in case, "God forbid, you ever had to work." Her real job at the university was to find a husband, which she did her junior year. The writing came after she had her two children, daughter Randy and Lawrence.
"I wanted to write honestly about kids because I didn't feel that the adults in my life were ever open and honest with me," she said. "The war had just ended, and we wanted to know what happened. Every story I made up in my head about what really happened was worse than what anybody could have told me."
Today, Blume contemplates the final chapter in her career. Happily married for 33 years to George Cooper, a retired law professor and an executive producer on "Tiger Eyes," Blume splits her time between New York City and Key West, Fla. She joked that Cooper ruined her career: "I got happy, and to write you need a lot of angst."
A recent breast cancer survivor, Blume said that when she dies she wants a headstone that reads, "Are You There God? It's Me, Judy."
But she's not willing to go yet. She's contemplating relocating to Santa Monica for a few months this summer to continue working on her novel. She doesn't have a deadline for the book but hopes to finish the story — set in her hometown in the 1950s — "in her lifetime."
"My mother used to knit, and when she finished a sweater she always had the wool for the next sweater because she made bargains with God. God would not take her when she was in the middle of a sweater," she said. "I used to make a lot of bargains. I don't make a lot of bargains anymore."


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Dear collectors,
let us kindly inform you that we have started one week round with the title FAC # 38 THE GOOD DINOSAUR for still collectible numbers 0 - 750.
FAC # 38 THE GOOD DINOSAUR 3D + 2D FULLSLIP + Lenticular MAGNET includes:
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The EMT Program and Health Sciences curriculum provides students with the technical knowledge and practical skills training for a career in pre-hospital care and other allied health professions. The EMT program focuses on the critical thinking skills necessary to meet the rigorous testing standards of the National Registry of Emergency Medical Technicians (NREMT) and reciprocal state certification and licensing requirements.
Students who successfully earn the NREMT and State EMT Certifications, will meet minimal occupational requirements to start a career in Emergency Medical Services and related allied health fields. The EMT program is instrumental in launching the careers of students as professional firefighters, EMTs and paramedics with pre-hospital care providers, emergency room technicians, burn unit technicians, as well as a variety of other full and part-time opportunities within the industry.
EMT certification has also become a valuable stepping stone in the path of students pursuing careers as physicians, registered nurses, physician assistants, and other health professions, by offering a distinct advantage in patient assessment and critical intervention skills, as well as the ability to obtain valuable work experience.Information on EMT licensure examination pass rates is available at National Registry of EMTs EMT Pass Rates
The EMT program is a comprehensive curriculum of lecture and training that provides knowledge and critical thinking skills necessary to provide Emergency Medical Care in a pre-hospital environment. Covers legal and moral aspects, scene safety, primary and secondary patient assessments, intervention and stabilization skills, proper use of emergency medical equipment, awareness of bloodborne pathogens and communicable diseases, recognizing signs and symptoms, and pathophysiology of medical emergencies and traumatic injuries. Includes practical hands-on skills training and interactive simulations. Twenty-four (24) hours of Clinical Experience is an assigned field ride-along and/or clinical hospital internship. Attendance and participation is mandatory; an accumulative score of 80% on all written quizzes and exams, and a passing score on all NREMT practical skills testing is required for successful course completion.
Meets the EMT-1 curriculum requirements of the California Code of Regulations Title 22, the California EMS Authority and the National Registry of Emergency Medical Technicians (NREMT). Upon successful completion, students are eligible to take the National Registry EMT certifying examination and qualify for a California State EMT certification. A total of 166 course hours include: 142 lecture and skills lab, and 24 hours of assigned field/clinical internship.
Course Prerequisites:
Highly recommend completion of HSCI 7 and BIOL 55 with grades of "C" or better; eligibility for ENGL 11
The EMR-Emergency Medical Responder is a 54 hour course that provides the knowledge and skills for individuals to provide initial response emergency medical care. Training includes oxygen administration, airway adjuncts, bag valve mask, splinting and spinal immobilization. Emphasizes patient assessment and medical interventions at the First Responder level. Meets the National Curriculum Standards for Emergency Medical Responders. Curriculum includes the American Heart Association Basic Life Support for the Health Care Provider CPR card and the Emergency Medical Responder Certificate of Completion issued with grade of "C" or better. The Course is highly recommended prior to enrolling in the HSCI 02 EMT Course.
The HSCI 50 Intro to Paramedic course is 80 hours of comprehensive lecture and training to introduce the knowledge and critical thinking skills necessary to prepare for a Paramedic Program. The course is assessment based with a focus on EMT and paramedic interventions. Advanced skills introduced in the course include EKG recognition and interpretation; Pharmacology; Advanced Airway Management; IV and IO fluid and drug administration; Principles of Pathophysiology in Emergency Medical Care; and Introduction to Local and National ALS Protocols. Practical lab sessions will focus on improving patient assessment techniques, realistic case study scenarios, and introduction to paramedic ALS skills and interventions. The course format is interactive and will simulate the intense pace and discipline often required of a paramedic program curriculum. Student participation and passing of written exams and practical skills assessments will be required for successful course completion and to meet the minimal prerequisite requirements of several regional paramedic programs.
80 hours continuing education (CE) credit will be awarded to student who successfully meet the course completion and attendance requirements.
Victor Hernandez Is a retired Firefighter/ Paramedic from North Tahoe Fire and currently serving on the Truckee Fire District Board of... More


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Uncovering our family history can reveal saints and sinners as we dig through old newspapers. Genealogists using GenealogyBank become used to finding a scoundrel here and there on the branches of the family tree.
But British actress – Patsy Kensit was not prepared for what she discovered while filming a TV show for the BBC.
She was the featured star of an upcoming episode of "Who Do You Think You Are?" a UK TV show that uses the family history of celebrities in a format reminiscent of Ralph Edward's long running TV show This is Your Life.
Patsy Kensit became so upset when she found out that her Dad (who died when she was a teenager) and her grandfather were criminals – that she walked off the set while filming the show.
The show got her to come back and finish the filming after telling her that the segment would also highlight her praiseworthy ancestors – one who was an Anglican Priest, recognized by the Archbishop of Canterbury and another a respected local constable.
You can read the entire story in the UK newspaper the Daily Record (5 Aug 2008) – Patsy Kensit left in tears as BBC show reveals her family's gangland links.


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YEONGAM, South Korea - With a third straight victory, Sebastian Vettel is suddenly closing in on a third straight Formula One title.
The Red Bull driver won the Korean Grand Prix on Sunday to move ahead of Ferrari's Fernando Alonso in the F1 championship standings by six points with four races remaining — erasing what looked like a commanding lead for the Spaniard just three weeks ago.
Vettel started second on the grid behind Mark Webber but overtook his teammate on the first turn and never relinquished the lead, finishing 8.2 seconds ahead of Webber. Alonso was third, 13.9 seconds off the pace.
"The foundation was there with a good start," Vettel said. "I wasn't sure because I was starting on the dirty side of the grid, but I was able to get some good grip and get inside at the first turn."
Vettel, who also won the previous races in Singapore and Japan, now looks to be the favorite for a third straight championship title — something only previously achieved by Juan-Manuel Fangio and Michael Schumacher.
Ferrari's Felipe Massa was fourth, followed by Lotus driver Kimi Raikkonen and Force India's Nico Hulkenberg. McLaren's Lewis Hamilton finished a disappointing 10th, despite starting third on the grid.
It was Vettel's fourth win of the season and the first 1-2 finish for Red Bull. Vettel leads the driver's standings for the first time this year.
Vettel said it was too early to think about the championship.
"We've seen the championship go up and down, so we just have to focus on ourselves for the last four races," he said.
Alonso has not won since the German GP, when it looked as though he was going to run away with the championship. He was the innocent victim of first-lap collisions in Belgium and Japan but earned valuable points in Sunday's race.
"We're doing what we can at the moment," Alonso said. "We're trying to save points. It was a perfect Sunday for us: good start, good strategy during the race and finishing on the podium. I'm very happy with today's race and where we are in the championship."
Sauber's Kamui Kobayashi made contact with Jenson Button on Turn 3 of the first lap, sending the McLaren driver to an early exit. Kobayashi was handed a drive-through penalty for causing the collision. Mercedes driver Nico Rosberg also went out on the first lap.
Hamilton, who is fourth in the standings at 62 points behind Vettel, had a rear suspension problem with his McLaren and even got a piece of artificial turf from the edge of the track stuck under his car late in the race.
Red Bull also increased its lead in the constructors' championship with 367 points, 77 ahead of Ferrari. McLaren dropped to third place with 284 points.
The next race is Oct. 28 in India.


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Table of Contents
> HAART resistance genotyping
HAART resistance genotyping
Related terms
Future research
Author information
Related Terms
Antiretroviral, antiretroviral resistance genotyping, GeneSeqTM, GenoSure (Plus)TM, genotypic assay, genotype testing, HAART, highly active antiretroviral therapy, highly active antiretroviral therapy resistance genotyping, HIV-1 TrueGeneT, human immunodeficiency virus, mutation, opportunistic infections, PCR, phenotype testing, polymerase chain reaction, PR region, retrovirus, RT region, sequencing assay, ViroSeqTM.
Human immunodeficiency virus (HIV)
: HIV is a retrovirus that causes AIDS (acquired immune deficiency syndrome), a disease of the human immune system. Retroviruses are a group of viruses that contain ribonucleic acid (RNA) and replicate by reverse transcription. Reverse transcription is the process of producing a double-stranded deoxyribonucleic acid (DNA) from a single-stranded RNA.
The retrovirus primarily attacks the body's immune system, making the body extremely vulnerable to opportunistic infections. Opportunistic infections are infections that occur in people with weak immune systems (and generally do not occur in healthy people). Examples of such infections include toxoplasmosis, cytomegalovirus, and
Pneumocystis jiroveci
pneumonia (formerly called
Pneumocystis carinii
or PCP).
HIV-1 and HIV-2 are the two known strains of HIV. The HIV-1 virus is highly infectious (virulent), relatively easily transmitted, and is the cause of most HIV infections globally. HIV-2 is less easily transmitted and is largely confined to West Africa.
Highly active antiretroviral therapy (HAART)
: HAART refers to the combination of multiple antiretroviral drugs used to treat HIV-positive patients. Antiretroviral drugs inhibit the ability of HIV or other types of retroviruses to multiply in the body. Some of the classes of antiretroviral drugs include reverse transcriptase inhibitors, protease inhibitors, and integrase inhibitors. Reverse transcriptase inhibitors are drugs that inhibit the enzyme reverse transcriptase, which is required for the reverse transcription process. Reverse transcriptase inhibitors include zidovudine, tenofovir, and efavirenz. Protease inhibitors are drugs that inhibit the viral protease, an enzyme that HIV uses to produce infectious viral particles. When protease is blocked, new copies of HIV are not formed properly, and they are unable to infect new cells. Examples of protease inhibitors include saquinavir, ritonavir, and indinavir.
Resistance to HAART
: Resistance to HAART is an important cause of treatment failure, and it is estimated to be as high as 50% among those receiving treatment in the United States. Resistance is the capacity of disease-causing microorganisms to withstand exposure to drugs previously toxic to them. It is acquired either through spontaneous mutation or by gradual selection of a relatively resistant virus after drug exposure.
Determination of resistance has implications not only in the treatment of the individual patient, but also among the general population because they may be exposed to drug-resistant viruses. Another critical problem is the possibility that a resistant strain may have resistance to other drugs that have not yet been prescribed in that particular patient (cross-resistance).
Mutations causing resistance
: A point mutation involves a single nucleotide; it may consist of the loss of a nucleotide, substitution of one nucleotide for another, or the insertion of an additional nucleotide. A region in the HIV-1 gene that codes for the protease enzyme is called PR, and the region that codes for the reverse transcriptase enzyme is called RT. Some of the point mutations that confer antiretroviral resistance include RT M184V (amino acid methionine is replaced by amino acid valine at position 184 of RT), PR V82A (amino acid valine is replaced by amino acid alanine at position 82 of PR), and PR I84V (amino acid isoleucine is replaced by amino acid valine at position 84 of PR). Amino acids are the building blocks of proteins. Proteins are any of a group of complex organic macromolecules that contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur and are composed of one or more chains of amino acids.
Causes of resistance
: Causes of resistance include reduced compliance with treatment; reduced absorption and metabolism of a drug in individual patients; initiation of antiretroviral therapy at an advanced stage of HIV infection; host genetic variability to drug efficacy and HIV susceptibility; drug interactions; poor follow-up; and prescription of ineffective regimens. Drug metabolism is the enzymatic degradation or modification that a drug undergoes in the body. Host genetic variability refers to the variations in the genetic makeup of individuals, which may result in differences in response to a drug. These factors lead to selection of pre-existing or newly developed resistant strains. Identification of the presence of drug resistance in a patient helps the healthcare provider choose the right combination of antiretrovirals to suppress the viral replication in the patient.
Drug resistance testing
: Drug resistance testing is used to determine whether an HIV patient has a mutated form of the virus that does not respond to antiretroviral therapy. There are two main types of drug resistance tests: genotypic and phenotypic. Genotypic tests examine the genetic structure of a patient's HIV, while phenotypic tests examine the sensitivity of a patient's HIV to a specific drug. Genotype is the genetic constitution of an organism. Phenotype is the manifestation of a genotype or the combined manifestations of several different genotypes. Genotype assays are tests that detect viral mutations that may cause changes in viral susceptibility to particular drugs or classes of drugs. The assay makes use of polymerase chain reaction (PCR), which amplifies (copies) the HIV-1 gene of interest from the patient's blood samples. PCR is an enzymatic method for the repeated copying of the two strands of DNA of a particular gene sequence. It is widely used to amplify minute quantities of biologic material so as to provide adequate specimens for laboratory study. Phenotypic assays first insert the patient's PR and RT genes into a standard reference virus, then test the amount of drug required to inhibit the virus replication by 50%. The test is done
in vitro
, that is, under laboratory conditions and not in the patient.
Types of genotype assays
: Sequencing assays and point-mutation assays are the two types of genotypic assays.
Sequencing assays are used to detect mutations in either the reverse transcriptase or protease genes. Both of these genes are involved in the replication of HIV. Reverse transcriptase is an enzyme that allows HIV and similar viruses to insert their genetic information into the DNA of a human cell, causing the cell to produce more viruses. Proteases are a class of enzymes that degrade proteins by breaking the peptide bonds that join the amino acids in a protein. The HIV virus makes use of proteases to split proteins during the assembly of virions (virus particles). Point-mutation assays are used to detect mutations that are known to cause drug resistance in these genes.
Current genotypic resistance tests include Bayer Health Diagnostics' HIV-1 TrueGeneT, Celera Diagnostics/Abbott Laboratories' ViroSeqT, LabCorp's GenoSure (Plus)T, and Monogram Biosciences' GeneSeqT. Among these, HIV-1 TrueGeneT is the only U.S. Food and Drug Administration (FDA)-approved genotyping assay kit.
: HIV-1 TrueGeneT genotyping kit is a sequencing assay. Sequencing assays are used to detect mutations in either the reverse transcriptase or protease genes. Both of these genes are involved in the replication of human immunodeficiency virus (HIV). Reverse transcriptase is an enzyme that allows HIV and similar viruses to insert their genetic information into the deoxyribonucleic acid (DNA) of a human cell, causing the cell to produce more viruses. DNA is the long thread-like molecule made up of large numbers of nucleotides. Proteases are a class of enzymes that degrade proteins by breaking the peptide bonds that join the amino acids in a protein. The HIV virus makes use of proteases to split proteins during the assembly of virions (virus particles). The assay is used in combination with the patient's clinical history and other laboratory tests, such as CD4 count and number of viral copies per milliliter, in the management of HIV-1, subtype B infection. RNA is a polymeric constituent of all living cells and many viruses, consisting of a long, usually single-stranded chain of alternating phosphate and ribose units with the bases adenine, guanine, cytosine, and uracil bonded to the ribose.
There are two major types of HIV, types 1 and 2. HIV type 1 is further classified into groups M, N, and O. Subtype B is a further classification under group M. There are two regions on the HIV-1 genome which code for resistance against antiretroviral drugs: the protease region (codons 1 to 99) codes against protease inhibitors, and the RT region (codons 40 to 247) codes against the reverse transcriptase inhibitors. A codon is a set of three consecutive nucleotides in a strand of DNA or RNA that provides the genetic information to code for a specific amino acid that will be incorporated into a protein chain or serve as a termination signal.
The protease region (codons 1 to 99) and RT region (codons 40 to 247) of the HIV-1 genome, where mutations that code for resistance against the antiretrovirals protease inhibitors and the reverse transcriptase inhibitors are found, are the targets of this assay.
The kit consists of three components: chemistry, hardware, and software. The chemistry kit consists of the reagents (chemicals) necessary to perform reverse transcription and amplification of the extracted RNA virion. A virion is the complete virus particle that is structurally intact and infectious. Reverse transcription refers to the production of a double-stranded DNA from a single-stranded RNA, and amplification (replication/multiplication) is the process of production of multiple copies of a sequence of DNA or RNA. Reagents for CLIP sequencing reactions of the protease I and reverse transcriptase portions of the HIV-1 genome are also present. CLIP reaction refers to amplification (replication/multiplication) by polymerase chain reaction (PCR) simultaneously with nucleic acid sequencing.
The hardware component consists of the Long-Read tower Automated DNA sequencer, MicroCelTM cassettes, and a polymerization unit, the GelToasterTM. The Long-Read tower can read a sequence of 1,000 bases within four hours when combined with the MicroCelTM cassette. The MicroCelTM cassette is a polyacrylamide, electrophoretic gel cassette, which acts as a medium for the Long-Read DNA sequencer. Elelctrophoresis is the movement of charged colloidal particles through the polyacrylamide medium in which the particles are dispersed as a result of changes in electrical potential. It is used in the analysis and separation of proteins. Proteins are any group of complex organic macromolecules that contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur and are composed of one or more chains of amino acids. The GelToasterTM is a device that polymerizes the acrylamide gel medium through which the DNA is separated. Polymerization is the process in which many small molecules called monomers are joined to form giant molecules called polymers.
The software assembles the data and determines the DNA sequences by reading the order of bases. It compares the DNA sequence of the patient's sample with that of an HIV-1 database and identifies the incompatible bases and produces the final report. The interpretation makes use of a set of criteria developed by an international panel of HIV-1 clinical and research experts and coded by the Visible Genetics Research & Development group, based on the GuideLinesTM Rules interpretation algorithm.
Interpretation of test results
: The results may be listed as one of the follows: no resistance, possible resistance, resistance, and insufficient evidence. When no mutations are detected or the resistance is not associated with the mutations detected by this assay, the result is ''no resistance.'' If the mutations detected by this assay are associated with a definite resistance, the result will read ''resistance.'' If the mutations detected by the assay have been associated with resistance in some patients or an
in vitro
reduction in viral susceptibility to a certain extent, the result is ''possible resistance.'' If no definite conclusion is drawn from the assay, then the result is given as ''insufficient evidence.'' The results help the clinician choose a suitable antiretroviral drug regimen to which the patient's HIV is not resistant.
The VIRADAPT study aimed at guiding treatment in patients who had treatment failure after receiving at least three months of a protease inhibitor-containing regimen. Protease inhibitors are drugs that inhibit the viral protease, an enzyme that the human immunodeficiency virus (HIV) uses to produce infectious viral particles. When protease is blocked, new copies of HIV are not formed properly, and they are unable to infect new cells. The study sought to evaluate if genotype testing resulted in antiretroviral treatment success in such patients. Genotypic tests examine the genetic structure of a patient's HIV. The study concluded that patients who underwent genotype testing were more likely to achieve HIV-1 ribonucleic acid (RNA) levels of <200 copies per milliliter at six months. About 32% of patients in the genotyped arm achieved HIV-1 RNA levels of <200 copies per milliliter at six months compared to only 14% in the control arm. Also, the results persisted at week 48 in the genotyped arm. RNA is a polymeric constituent of all living cells and many viruses, consisting of a long, usually single-stranded chain of alternating phosphate and ribose units with the bases adenine, guanine, cytosine, and uracil bonded to the ribose.
Genotype testing for human immunodeficiency virus (HIV) is recommended in recent HIV infections; before starting antiretroviral therapy in known cases of HIV; and in pregnant patients with detectable plasma HIV-1 RNA levels.
Genotypic resistance testing examines the genetic structure (genotype) of a patient's HIV. In recently acquired HIV infections, the test helps to identify the transmission of a drug-resistant virus and to identify the drugs to which the virus is resistant.
In known cases of HIV, the test helps to list the drugs to which the patient's virus is resistant, especially in patients in whom the first regimen itself failed. In patients in whom multiple regimens failed, a regimen to which the virus is susceptible can be chosen; genotype testing helps in determining this and ruling out all the ineffective regimens.
Pregnant women may be tested before initiation of antiretroviral therapy during pregnancy or to change a regimen. It is especially useful if the woman has been exposed to many antiretroviral drugs prior to pregnancy. The test aids the clinician in choosing the right regimen to treat the mother as well as to prevent transmission of the virus to the fetus.
Inability to obtain results or obtaining an inaccurate result by the use of genotype testing may result in patients receiving inappropriate therapy, thus making the patient susceptible to unnecessary adverse effects and increasing the cost of treatment.
The present genotypic assays require plasma HIV-1 ribonucleic acid (RNA) levels to be greater than 500-1,000 RNA copies per milliliter of blood.
Due to the high cost of the genotyping kits, they are not used regularly in developing countries. Efforts are being made to develop cheaper kits with effectiveness similar to the standard commercial kits for use in these regions, where the disease burden is higher.
Occasionally genotype testing may yield inaccurate results, and this may result in patients receiving inappropriate therapy.
Future research
In addition to monitoring the patient's therapy by reviewing side effects and CD4 counts, monitoring drug levels may be of use. Therapeutic drug monitoring (TDM) is an emerging tool in the treatment of human immunodeficiency virus (HIV) patients. TDM refers to the measurement of drug levels in the blood. Usually the blood is drawn just before the next dose is due. It is especially useful in patients who are receiving drugs that interact with one another as the test helps to determine if the required plasma level of the drug is being achieved. Further research is ongoing, and the present data shows that TDM is useful when used along with resistance testing.
Author information
This information has been edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).
Centers for Disease Control and Prevention.
Chaix-Couturier C, Holtzer C, Phillips KA, et al. HIV-1 drug resistance genotyping. A review of clinical and economic issues. Pharmacoeconomics. 2000 Nov;18(5):425-33.
Fiscus SA, Adimora AA, Schoenbach VJ, et al. Trends in human immunodeficiency virus (HIV) counseling, testing, and antiretroviral treatment of HIV-infected women and perinatal transmission in North Carolina. J Infect Dis 1999; 180:99-105.
Hanna GJ, D'Aquila RT. Clinical use of genotypic and phenotypic drug resistance testing to monitor antiretroviral chemotherapy. Clin Infect Dis. 2001;32:774-782.
Hirsch MS, Günthard HF, Schapiro JM, et al. Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel. Clin Infect Dis. 2008 Jul 15;47(2):266-85.
Natural Standard: The Authority on Integrative Medicine.
Sukasem C, Churdboonchart V, Chasombat S,et al. Surveillance of genotypic resistance mutations in chronic HIV-1 treated individuals after completion of the National Access to Antiretroviral Program in Thailand. Infection. 2007 Apr;35(2):81-8.
Van Laethem K, Vandamme AM. Interpreting resistance data for HIV-1 therapy management--know the limitations. AIDS Rev. 2006 Jan-Mar;8(1):37-43.
Van Vaerenbergh K. Study of the impact of HIV genotypic drug resistance testing on therapy efficacy. Verh K Acad Geneeskd Belg. 2001;63(5):447-73.
World Health Organization.
Wilson JW, Bean P. A physician's primer to antiretroviral drug resistance testing. AIDS Reader. 2000;10:469-478.
Copyright © 2011 Natural Standard (
The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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text:
Dr. Lesley A. David, Canada – immediately loaded full-arch rehabilitation using NobelGuide
Situation: 65-year-old male, edentulous in the upper jaw. The dentures were made six years prior.
Solution: In the maxilla, five Brånemark System Mk III Groovy implants and one NobelSpeedy Shorty implant were placed. As a final restoration, a NobelProcera Implant Bridge Titanium with acrylic teeth was chosen.
View case (PDF, 228 kB)


text:
Emma Bern will celebrate her 90th birthday on Sunday.
She was born on February 6, 1921, to Joseph and Mary (Yuska) Kubik from Traer. Emma married Leslie Bern from Gladbrook on June 1, 1946.
Her family includes one daughter, Marlis (Larry) Helland from Reinbeck, and a granddaughter, Lisa Helland from Plymouth, Minn.
Article Photos
Emma Bern


text:
Hoyer Remarks at the National Association of Manufacturers 2012 Manufacturing Summit
Katie Grant, 202-225-3130
WASHINGTON, DC - House Democratic Whip Steny H. Hoyer (MD) spoke at the National Association for Manufacturers' 2012 Manufacturing Summit today, where he discussed House Democrats' Make It In America plan. Below are his remarks as prepared for delivery:
"Right now, in this room, many of you are busy typing away on your smartphones, broadcasting snippets of information to the remotest corners of our world. Texting, tweeting, email – all have become ubiquitous tools in the transfer of information and the latest step in the march of innovation. We live at an exciting moment when we can feel the pulse of change literally in our fingertips.
"A hundred years ago, Americans were experiencing this same feeling of living on the cutting edge of innovation. Electricity, the telephone, motorized transport – all of the developments in industry and technology imbued our people at the dawn of the twentieth century with an optimism that America would become the greatest producer of goods on Earth.
"Their faith was not misplaced. It is very doubtful, however, that they could not have imagined the scope of our advances in science, technology, and communications.
"This raises the question: what will our world look like a hundred years down the road? We must ask ourselves: can we repeat that extraordinary performance? And we must answer confidently: yes!
"We may not be around to witness how far we'll have come, but we can lay the groundwork today to shape that future world and America's place in it.
"I believe – and I am sure you will agree – that doing so begins with manufacturing.
"Economic indicators show manufacturing to be the brightest spot in our recovery. The Institute of Supply Management purchasing managers' index continued to show growth in May, representing the thirty-fourth consecutive month of manufacturing gains, and manufacturing productivity increased 5.9 percent in the first quarter of this year. Industrial production, as measured by the Federal Reserve's Industrial Production Index for Manufacturing, has surged 20% from its lowest point in June 2009.
"The private sector as a whole has been adding jobs for the past twenty-seven months straight, and, undoubtedly, manufacturing has been a prime contributor to this trend, with half a million manufacturing jobs created since January 2010 – and with many non-manufacturing jobs created in communities that have benefitted economically from new manufacturing investment.
"Manufacturing jobs traditionally have been jobs that pay well and help working families rise to the middle class. Right now, with millions still out of work, our best strategy for job creation over the near and long terms is to invest in our manufacturing sector.
"As you well know, manufacturing has a larger multiplier effect than any other sector, generating – dollar-for-dollar – more output from other sectors of the economy. In order to capitalize on recent gains and make sure their effects are widely felt, it simply makes good economic sense for Congress to encourage further manufacturing growth.
"House Democrats' plan to do so is called Make It In America. Our aim is to help your manufacturing businesses succeed and grow, which in turn will lead to greater opportunities for American workers, their families, and entire communities.
"Those are the two meanings of Make It In America. First, we want to help you "make more" products here – build it in America, grow it in America, and sell it here and around the world. Second, by doing so, you'll help more Americans "make it" here in this country – that is, do well, move up, and realize the promise of the American Dream.
"Our Make It In America plan is multi-pronged in its approach, combining tax incentives for moving production here with federal investment in infrastructure, education, and innovation – all the things necessary for businesses to expand and grow. And, as well, we must ensure that regulations do their needed job without impeding and preventing the growth we need.
"This also includes export assistance. President Obama, in his 2010 State of the Union address, set an ambitious goal to double American exports by 2015. We are now on pace to meet that goal, thanks in part to bipartisan efforts that passed three free-trade agreements last year and reauthorized the Export-Import Bank in May.
"I was proud to join President Obama when he signed the Ex-Im Bank reauthorization into law. Many of you were there. In doing so, he extended its charter and expanded its financing authority by 40% over the next three years. Support from the National Association of Manufacturers was instrumental in securing the bipartisan coalition that passed the Ex-Im reauthorization through both chambers with strong majorities – including unanimous support from Democrats in the House.
"Ours has long been the party of manufacturing in America, and we will continue to be your champion in Congress as we work to pass more Make It In America legislation into law.
"This was the case in 2009, when our auto industry was on the brink of collapse. While some said it should simply be allowed to fail, President Bush, President Obama, and Democrats in Congress placed a bet on America's auto workers, and that bet has paid off. Today, auto manufacturing is thriving and helping to lead our recovery.
"While creating jobs in the short term is a central goal of our plan, it is not the only goal. Make It In America is an ambitious, forward-looking legislative program that will set us on a course for long-term economic competitiveness. That's why we call for strategic investments in education, innovation, and support for research, development, and deployment of advanced technologies that will help us achieve greater domestic energy security, provide energy for manufacturers, and continue our pursuit of an all-of-the-above energy policy.
"Andrew Liveris, the CEO of Dow Chemical, has spoken eloquently and compellingly about the need to do all of that in his book: Make It In America.
"An all-of-the-above energy policy, of course, includes investing in natural gas, wind, solar, and cutting-edge biofuels. And nuclear power, as well. Advanced energy technologies have enormous potential as a catalyst for sustained economic growth – an area where our competitors are hoping to overtake us. But we have a significant advantage our competitors might not have accounted for: the indomitable American spirit of enterprise, hard work, and constant innovation.
"But Liveris and Andy Grove, of Intel, and others have warned us that, if production goes overseas, inventors, innovations, and developers will follow.
"One way to make sure that spirit of enterprise is allowed to thrive is by simplifying our corporate tax code and rationalizing our regulatory environment. Businesses should be freed to make decisions that make the most business sense – the best economic outcome, rather than the best tax outcome. Our current system is far too complex. There is a growing bipartisan consensus that we can bring down rates, increase international competitiveness, and broaden the base to raise the level of revenue necessary to fund investments in infrastructure, education, and innovation that will help maintain America as the leading economic power.
"Innovation has always been the key to success in American business. Our competitors have been funding research and development with the future in their crosshairs. Our Make It In America plan prioritizes strong investments in innovation and research so we can help your businesses continue to compete successfully in the global marketplace. We cannot afford to let our competitors be the only ones with their eyes focused on the distant horizon.
"We've also seen our global competitors graduate more and more engineers and students with the technical skills needed in the twenty-first century. If we're going to compete, manufacturers need a skilled and trained workforce. Our Make It In America plan invests in partnerships between businesses, community colleges and local workforce development professionals to train our next generation of skilled workers. It also includes the AMERICA Works Act, which will prioritize training programs that lead to industry-recognized, nationally portable credentials. We also ought to be moving forward with a bipartisan reauthorization of the Workforce Investment Act that invests in long-term skills attainment, especially for those workers facing the greatest hurdles to finding jobs. Our workforce is the most productive in the world, and we want to give American workers the chance to do what they do best.
"Innovation and public investment in education and infrastructure were responsible for the advances that made our country into the world leader it is today and fulfilled the distant dreams of Americans at the dawn of the twentieth century.
"But the America inherited by future generations of Americans a century from now depends on what work we begin today.
"When President Kennedy spoke to your organization in 1961, he declared: 'The hour of decision has arrived. We cannot afford to "wait and see what happens" while the tide of events sweeps over and beyond us.'
"This year the American people will make a choice about the direction of this country. We can choose between those with a bold plan for the future and others who have chosen to take no action on manufacturing and instead simply to 'wait and see.'
"We can choose between those who are willing and ready to 'go big' – and achieve a serious and comprehensive solution to deficits – and those who instead have held our fiscal future hostage.
"Let me reiterate what I've said many times before: achieving comprehensive deficit reduction would be the greatest possible stimulus to our economy. It would restore certainty to our markets so businesses like yours can invest with confidence and grow.
"Reducing deficits and creating jobs are the two most important issues facing our nation today, yet we have seen little movement on either from this Congress. We must not put America's creditworthiness at further risk and should not use the debt limit extension as a political football. Some countries hit hard by the global financial crisis do not have the resources to invest in growth and pursue deficit reduction simultaneously. Thankfully, we do. We just need to muster the will and the courage to do so.
"Make It In America is bold, and it is the right plan for our time. If put into action, its effects will not be felt only in our time.
"If we do carry it out, we can promise our grandchildren that, at the start of the next century, America will still be strong, and our economy will continue to lead the world.
"That is the promise we ought to make. It is a promise I know we can keep.
"Let's not 'wait and see what happens.' Together, let's make it happen."


text: Element Skateboards is a highly successful skateboard company based in Irvine, California. Its roots were originally planted in Atlanta, Georgia in 1992 under the name Underworld Element. Commonly known as U.E. or Underworld, the company began to grow and change pace. So did the company name. The decision was made to drop Underworld, and it became known simply as Element. Element Skateboards adopted the principles of martial arts and the purities that were associated with it. They wanted to separate themselves as a company from their competition by making it a universal company that all people could personally identify with. They began to focus their attention on the future of the brand; what it represented and the way the world perceived it. In an effort to shine a positive light on the global skateboarding community, Element Skateboards created the masterful Department of Elementology. With the idea of designing innovative and quality products that promote an environmentally-friendly skate culture, Element created programs such as Elemental Awareness and Element Endangered.


text:
Regular check-ups
Get your eyes tested every two years even if you think your vision is fine. Some eye conditions -such as open angle glaucoma - may not show any noticeable symptoms so regular check-ups are vital.
Quit the habit
If you smoke, you have another good reason to kick the habit. Smoking is directly linked to blindness. Current smokers are four times more likely to develop macular degeneration (the UK's leading cause of blindness) compared to past smokers or non-smokers.
It's all relative
Talk to your relatives about your family eye health history as some eye conditions have genetic links such as glaucoma or squint.
It is important that you share this information with your optometrist or eye health professional.
Be cool in the sun
Protect your eyes when it is sunny or when you're in high glare areas such as near snow or water. Cumulative UV exposure can increase your risk of developing cataracts or macular degeneration.
When choosing sunglasses make sure that they are safe as well as stylish! Look out for the CE or BS EN 1836:2005 marks -- this ensures that they provide a safe level of protection from the sun's damaging UVA and UVB rays.
Contact care
If you wear contact lenses make sure you look after them properly.
Thoroughly wash and dry your hands before touching your contact lenses or your eyes and only ever clean your contacts using the contact lens solution recommended by your practitioner.
Never shower, sleep or swim with your contacts lenses in because this can put you at risk of developing a serious eye infection, which could lead to blindness.
Also, don't wear them for longer periods than those recommended by your optician.
Protect your eyes
If you work with hazardous or airborne materials at work or home, wear safety glasses or protective goggles to protect your eyes from injury.
Keep fit and healthy
Regular exercise is essential to stay fit and healthy but it is also important that when playing sports such as squash that you wear protective eye wear such as helmets or sports goggles to protect your eyes from a flying ball.
Eat well
Protecting your eyes starts with the food you eat. Studies have shown that nutrients in omega-3 fatty acids, zinc and vitamins C and E may help to prevent age-related vision problems such as macular degeneration and cataracts.
Foods containing eye-friendly nutrients include green leafy vegetables, oily fish such as salmon and citrus fruits.
You should also ensure that your alcohol intake is within the Department of Health's recommended limits.
Be screen smart
Although working at a computer will not harm the health of your eyes, sitting staring at a screen for long periods can cause 'screen fatigue' -- sore, itchy or tired eyes; headaches; impaired colour perception and temporary blurring of your vision.
So, it's important to take regular breaks to keep your eyes feeling fresh and bright.
For more advice about caring for your eyes visit www.visionmatters.org.uk
Contact: Rachel Robson
((M2 Communications disclaims all liability for information provided within M2 PressWIRE. Data supplied by named party/parties. Further information on M2 PressWIRE can be obtained at http://www.presswire.com on the world wide web. Inquiries to firstname.lastname@example.com)). © 2013 M2 COMMUNICATIONS


text: Westeros #1 Posted March 9, 2010 Storms had rained their fury on Blackwater Bay and King's Landing, and it was storms to blame, their downpours and their winds, for the long delay in news from Dorne. So when the rains stopped, temporarily, it seemed perhaps that news would arrive at last…But it never rains, without it pours.First a bird arrived bearing happy news, though two weeks out of date: the Dornish had sought a parley to render their surrender to the king outside of Godsgrace, shortly after their defeat and the death of Prince Rhodry Nymeros Martell, the brother of the Prince of Dorne. This news led to much cheer in the hall of the Old Keep, with Prince Aegon and his rascals matching cup for cup as they discussed the pleasures of Dornish women. Princess Daena and her companions were there as well, and Princess Naerys's chief lady companion, Reyna Saltcliffe, whose husband the Iron Serpent fought in the king's company alongside her brother the Lord Protector of the Reach, Ser Ardon Tyrell. Even the cold, solitary northwoman Aisling Ryswell found cause to be there, to hear the gossip and the news, as did Rosalind Buckler with her babe on her lap, doubtless thinking of her husband Ser Endros who had joined the campaign. Despite the loud, obnoxious carousing of Aegon and his cronies, the mood was good.And then…A man of Prince Viserys's household entered, near to weeping. When silence came, the news he delivered was terrible, nightmarish: the king was dead, his army shattered, scattered to the winds. Tears, screams, prayers—they all followed, a cacophony once the initial shock was done. Some cast doubts, denied—_denied_—that it could be so. But it was, oh, it was. The treacherous Dornish had parleyed under false pretenses, had murdered the king under the holy peace banner, damning themselves to hell. But what could one expect, of Dornishmen? And his Kingsguard? The much-honored Ser Reynard, the Lord Commander, was dead. So too was the bold Green Oak, Ser Olyvar Oakheart, and the Breaker of Yronwood, Ser Osbert Bettley. What then of the most famous knight of them all? Prince Aemon the Dragonknight? Captured, they said, captured and in Dornish hands. It was left unsaid that it would have been more merciful for him to have a swift death.Prince Aegon, the Dragonknight's brother and the king's cousin, drank harder than ever, draining cup after cup in silence. One man urged him to have his vengeance on the Dornishmen by executing the hostages; was not his father the Hand gone away on the Rosby road, leaving the castle to him? Was not—Aegon struck the man down, and commanded him to silence, and resumed his drinking.News had reached the Dornish tower, as well, of the surrender—Lady Joleta's husband, Ser Ethos Mertyns, had written of the Dornish surrender, and she shared the news with many of the hostages after having informed Prince Cadan. It was a sad gathering, unlike the rest of the castle. When bells began to ring, the bells of the royal sept, Ser Aidan Dayne answered that that must be for a fresh raven bearing the news of the king's final victory, the end of the Dornish rebellion… but then he looked out an arrow loop and realized it was something quite different: servants were weeping, there were laundresses wailing, guards running here and there, and more bells began to ring. It seemed, after all their worries, that the king was dead, or some disaster had befallen him and his grand army. And in the keep? At last Prince Aegon spoke, and asked the message-bearer the one question that had not been asked: who had done the deed? Who had killed the king? And the knight replied, it was Prince Rhodry, Prince Rhodry Nymeros Martell. This set Aegon's cold rage into drunken fury. He gave commands: fetch Damarya Allyrion and Corrent Gargalen from their cells, fetch Valeria Blackmont from her solitary place in the Kitchen Keep ... and follow him to the Dornish tower, every man among them, to seize the Dornish hostages and drag them to Traitor's Walk where they would pay in blood for the crimes of their kin.Not all were in agreement. Princess—now Queen—Daena protested this, attempted to stop her cousin. Lady Reyna sent men to race as swiftly as they could onto the Rosby road, to find Prince Viserys and bear him the dire news. Lady Aisling fled the Old Keep, perhaps out of fear for the bloodshed to come. But nothing would hold Prince Aegon, nor his unruly mob, whose ranks swelled as they left the keep and made their progress towards the eastern end of the castle.The Dornish did not sit idle, however. Lady Joleta and Prince Cadan had, it seemed, done far more to defend the Dornish in such a case than any of their fellows imagined. They had a plan for escape, thanks to the Gargalen heir's efforts to find one of the rumored secret passages. She had found one, one that could lead them from the castle and perhaps the city. But first, the Mertyns guardsmen her unwanted husband had set on her were in the room, and outside were four of the castle's guards.What to do? Prince Cadan gave the command to Ser Aidan Dayne, the best of the knights, to see to overwhelming the men, taking their garb, and helping to first lead women and children—Princess Ariana, his sister, chief among them, and his own mistress as well, his Lysene concubine—out of the tower without drawing suspicion. Ser Aidan hesitated, muttering about taking care, while his cousin Tanyth Toland and her twin Ser Tamlyn seemed dubious of the plan entirely. Was it not better to barricade themselves in the tower? As Ser Aidan argued, the new king, Baelor, was a godly youth, and one like to be merciful. But the plan was prepared, and the Prince and the heir to Salt Shore feared that there was no hope from that quarter. For one thing, Prince Baelor had a habit of attending the afternoon sermon at Visenya's Sept, attending on the High Septon himself. Who would bear a message swiftly enough to him, if someone like Aegon decided to be rid of them? No, they must carry out the plan, and Ser Aidan acquiesced. Joleta's minders were beaten unconscious, and then the guards outside were tricked into entering—all but one, who left to seek more aid—when they were told that the Mertyns men were brawling with certain Dornish knights. Overwhelmed as well, with one of them killed by Ser Tarion Sand, the knights donned the garb of the guardsmen, while those who were about to escape donned plain brown cloaks in hopes of not drawing attention. The first group slipped out, Lady Joleta leading the way, Ser Aidan and two knights guarding Allia of Lys as well as the children Princess Ariana, Selara Dalt, and Farien Yronwood. They crossed the yard, trying to be inconspicuous, guardsmen escorting common women and children…... when Prince Aegon and his mob arrived. Ser Halbert Cordwayner of the Kingsguard had joined them, rather than trying to prevent the prince, and at a window Lord Terin Ryger, the master of laws, could be seen watching events unfold without lifting a finger. The mob loomed nearer, nearer ... and then some men noticed the little group, trying their hardest to appear normal, perhaps trying too hard to do so, or given away by the dark skin of Ser Aidan's face as he threw a fearful glance over his shoulder. Aegon sent men to pursue them, and the Dornish hostages fled for their very lives! The rest of the mob drew on to the Dornish tower, when Prince Cadan—half-naked, stripped to smallclothes and his cloak so he could be as swift and light as he could be with his bravo's sword—and others charged out, a valiant attempt to sacrifice themselves and delay the mob from sending more men after the children.It almost worked. Prince Aegon was slashed and stabbed several times over by the whipping, darting blade of the Martell prince, Tanyth Toland's knife stabbed more than one man, swords rang briefly—but they were too many, far too many. Like a tide, men dragged down Dornish hostages, clubbing them with spear shafts and the butts of polaxes, seizing them with jeering, mocking cries. Some managed to fight their way back to the tower, and they shut the door behind them, and held it.Men were sent to fetch polaxes and halberds to batter down the door ... but then there was a surprise: the escaped Dornish were brought back under guard. Did Aegon's mob catch them? No. Preston Wayn, the lame master of whisperers, and a troop of Viserys's household knights had intercepted him. The whys and hows of it would remain a mystery to the mob, who cared little for anything other than blood. Yet Wayn attempted to protest Prince Aegon's plans, only to have Aegon knock him aside.Seizing hold of the young Martell princess, Ariana, Aegon shouted that he had her and she would die. In the Dornish tower, the grief-maddened Cadan attempted to open the barricaded door, to escape to his sister, only to be restrained by the Tolands and others. He collapsed, weeping. The polaxes began to cut into the door ... and now their hopes crushed, the hostages had little they could do but wait. And then the doors were splinters, and they were dragged out, most giving themselves up to their fate with little struggle. Joining those captured earlier, they were marched towards Traitor's Walk, as Aegon had the gates of the castle opened to the Kingslanders outside who had gathered to shout for the blood of the Dornish as the news of Daeron's death were tolled from every sept in the city. The prince, furious in his drunken way, condemned even the beautiful Cassella Vaith, his own mistress and the mother of his children. It was a dreadful sight to see her tears, screaming his name as she was dragged away with the others. Then Lady Aisling Ryswell arrived, riding bare back on her lathered black stallion, trying to tell the mob to stop, that Baelor had been informed, that Baelor was coming even now in all haste.The only effect was to make Aegon hurry, however. Of all the hostages, it was Prince Cadan who was brought to the block to die first. He fell to his knees, battered and bloodied, grief-stricken as the crowd howled for his blood.But something had changed in the yard, as out by the gate the crowd suddenly began to grow quiet, and this rippled through the mob. The crowd began to part, men and women alike began to kneel: it was Baelor, riding pillion behind a white knight, Ser Jaesin Lannister of the Kingsguard. Even Aegon came to kneel, and over his face passed a look of intense ill-ease. Baelor came to the platform on which Cadan knelt, and alighted from the horse. He climbed up, and in his high, clear voice he urged that now was a time for prayer and mourning, not for death. With his own hands, the new-made king lifted the weeping Prince Cadan to his feet, and with the sleeve of his own robe did the Targaryen king clean blood from Cadan's face. Some whispered in the sudden silence that he named the Dornish prince brother, and he forgave Prince Rhodry in the same breath.And suddenly, it was over. The new king had come, and from him came such calm and such faith in the Seven that none dared gainsay him. When Baelor suggested Aegon should join his wife, Naerys, in prayer, the prince was meek in the face of it. When he ordered the hostages to be taken safely back to their apartments, it was done without hesitation. The crowd departed, no longer thirsty for blood, instead marvelling at the holiness of their new king, and ashamed of the monstrosities they were prepared to witness.So began the reign of Baelor the First of His Name, King of the Andals and the Rhoynar and the First Man, Lord of the Seven Kingdoms, and Protector of the Realm. Even though he did not yet wear the crown, he was king in all ways that it mattered. When Prince Viserys arrived later that evening, a horse nearly dead under him, he found the Red Keep preternaturally calm. Where was Baelor, he asked? Praying, praying. Shortly after saving the hostages, forgiving his brother's killers, and restoring peace, Baelor had entered the royal sept. Not to thank the gods that he was king, no; to pray instead on the soul of the Young Dragon, his beloved brother Daeron, and on all the souls—subjects and Dornish rebels alike—that had perished in his war. Baelor would take no food or water, fasting and praying for a day and a night without sleep.After all this, the arrival of the white raven dispatched by the Conclave of the Citadel, marking the beginning of autumn, was hardly noticed…Visit the Site! Share this post Link to post Share on other sites


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A few weeks ago i tried strapless downwinder but struggled to keep the board on my feet during deep water starts, small jumps and messy waves.
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text: Nikki Montoya is a metalsmith and craftsperson based in Los Angeles. She first learned goldsmithing at her father's jewelry shop, and in 2010, she launched her first jewelry collection with the goal of creating well-made, reasonably-priced jewelry that adds a little edge to the everyday.Nikki is committed to quality craftsmanship, sustainability and local production. All of the materials she uses are locally sourced and assembled at her Silverlake studio.


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April 3: A raid on the FLDS-owned YFZ Ranch near Eldorado, Texas, begins. Law officers act on a warrant initiated by a phone call from a 16-year-old girl reporting sexual and physical abuse at the hands of an older man to whom she was "a spiritual wife."
April 5: 167 children taken into custody by Child Protective Services workers. Law enforcement officials with search and arrest warrants look for Dale Barlow, the man named in the young woman's phone call. A SWAT team breaks into the FLDS temple located on the ranch despite protests.
April 6: Sixty FLDS mothers voluntarily leave the ranch to be with their children at a makeshift shelter in San Angelo. State officials continue to search the compound for children. Child welfare workers say 18 children showed evidence of possible abuse.
April 7: A judge orders children, now numbered at 401, into temporary protective custody based on determination of significant risk of harm. A total of 133 women have now left the compound. Men on the ranch are not allowed to leave while investigation continues. Twelve attorneys hired to defend church members.
April 8: Affidavit released by the court outlines claims of physical and sexual abuse made by the teenage caller. A groundswell of opinion, pro and con, begins to grow.
April 9: Dale Evans Barlow, the accused abuser, denies allegations, says he hasn't been in Texas since 1977. Arizona probation officials agree it's unlikely he has been in Texas recently. Records and other items are seized amid allegations such seizure could violate pastor/parishioner confidentiality. A Deseret News/KSL poll shows 62 percent of Utahns find the raid "probably or definitely " justified.April 10: Three mothers report to the Deseret News they are being denied access to their children. Officials in Utah and Arizona say they hope information from Texas raid will help them in their investigations into other FLDS enclaves
April 11: Authorities release 88 pages detailing items seized from the ranch.The search continues for the girl now identified as "Sarah" alleged to have made the initial call. The Texas Bar seeks volunteer lawyers for each of the now 416 children in custody
April 12: Barlow meets with Texas Rangers in St. George, leaves a free man. Rangers refuse to say if he's still a suspect. Deseret News reporters and photographers become first media ever allowed inside ranch. Women from shelters speak with Deseret News on cell phones complaining of crowded conditions and uncertainty.
April 13: A judge orders all cell phones confiscated from FLDS women and children amid allegations the move was triggered by women talking with Deseret News reporters and sharing pictures taken with the phones. Utah Attorney General says Texas raid could compromise Utah efforts to keep communication with polygamists open. Eldorado newspaper prints legal notices of the court's actions, preparatory to upcoming court hearing.
April 15: Public opinion intensifies. Child welfare officials defend the raid, say they have homes lined up for children if the state retains custody. Former FLDS members have little sympathy, say the abuses of which the Texas group are accused really happen. The ACLU decries "colliding issues," declines to take a stand.
April 16: Hearings begin in 51st District Court with Judge Barbara Walther presiding. Tom Green County courthouse is filled to capacity, with overflow going to City Hall.
April 17: Ten hours of testimony stresses that while no signs of physical or sexual abuse have yet been documented among children in custody, the general culture of the polygamous sect puts them at risk. Hearing is punctuated by dozens of objections and lawyer requests to be heard on issues of unlawful search and seizure, venue, freedom of religion and authenticity of records. Police in Colorado Springs announce they have arrested a woman, Rozita Swinton, for investigation of making a false report to authorities and make a tentative connection to the Eldorado raid. Texas Rangers go to Colorado to investigate.
April 18: Walther rules that all 416 children are to remain in custody of state. Search begins for foster homes. Some mothers say they will drop lifestyle to retain children. Judge promises individual hearings for each child before June 5. After a search of her home, Colorado Springs officials say Rozita Swinton is a "person of interest" in the phone calls that set off the raid.
April 19: Texas officials say they will try to keep siblings and teenage mothers and their children together as placements are made and promise sensitivity to particular needs of the FLDS. State and federal prosecutors asked to screen evidence taken in search of Swinton's home.
April 20: FLDS lawyers say they will aggressively challenge court's decision.Collection of DNA samples to try to match parents with children begins.
April 21: Tally of children in custody rises to 437, with speculation the count still could change. Judge suggests LDS might supervise prayer gatherings of the FLDS to ensure mothers don't use time to indoctrinate children. Utah's Family Support Center says raid more harmful than helpful. FLDS mothers appeal to Texas Gov. Rick Perry. No meetings planned.
April 22: Up to 100 children are moved from San Angelo Coliseum as placement in foster care begins. Lawyers for FLDS claim many civil rights violations.
April 24: Distribution of children from San Angelo to foster care sites throughout Texas continues. Count of children in custody rises to 462. Salt Lakers protest Texas raid in demonstration outside EnergySolutions Aarena.
April 25: Texas 3rd Court of Appeals refuses to hear plea of 45 FLDS women to bar "scattering of children." Busing of children to foster care sites continues.
April 26: The last of the children leave the San Angelo area for foster care.
April 27: Two FLDS boys are reported "unaccounted for." Texas authorities express frustration with slow process of sorting through 1,000 boxes of items removed from FLDS ranch. Attorneys for the sect are stymied by the lack of progress in their ability to begin court actions protesting the raid.
April 28: Texas officials say more than half of the teenage girls removed from the ranch have children or are pregnan
April 29: FLDS lawyers take first steps to sue Texas in federal court for lack of due process in the raid and its aftermath. Utah Attorney GeneraL Mark Shurtleff and U.S. Senate Majority Leader Harry Reid, D-Nev., square off on differences regarding polygamy issues. The Nevadan says Utah and Arizona have been lax in prosecuting polygamy, approves of Texas raid. After discussion, the two agree to work together on issues. Reid later announced appointment of a Justice Department prosecutor to review federal role in helping state, local law enforcement efforts against polygamy.
April 30: Texas' top child welfare official tells a Texas Senate committee 41 of the FLDS children taken in the raid had historic evidence of broken bones, but an FLDS attorney says the report is part of the state's attack on the religion.
May 1: Group of FLDS mothers petition Texas 3rd Court of Appeals to reverse Walther's decision to remove children from ranch.
May 2: Texas Department of Public Safety acknowledges warrant against Dale Barlow has been dropped. Texas authorities issue "cultural awareness guide" to help social workers deal with FLDS children.
May 5: FLDS leader asks in a letter that Gov. Jon M. Huntsman Jr. intervene. After review, governor says Utah will look only at cases involving Utah children. Utah child welfare authorities ask FLDS for a list of such children.
May 6: LDS Church rebuts article on New York Times Web site making "invalid" comparisons of early LDS polygamy and FLDS practices.
May 7: ACLU expresses concerns regarding Texas handling of the raid.
May 8: Texas officials begin drafting "family service plans" for children.
May 9: Utah and Arizona attorneys general speak in St. George meeting, supporting Texas raid but stating such an approach would not be used in their states.
May 10: Texas CPS respond to FLDS mothers' petition, saying all children in the sect are at risk due to lifestyle and teachings.
May 11: FLDS spokesman Willie Jessop delivers a letter of appeal to President Bush, who is in Texas for daughter's wedding. As customary, the letter was to be screened through normal channels.
May 16: FLDS mother, 18, wins court "victory," is allowed to stay temporarily with her newborn and an older child.
May 17: Jeffs' attorneys asked that a grand jury indictment in Arizona cases be dismissed, citing flaws in the jury's processes and undue influence from the state of Arizona.
May 19: Custody hearings start for each affected family, expected to take three weeks. Utah Supreme Court docket shows Jeffs will appeal his Utah conviction.
May 20: Four more FLDS "disputed minors" are declared to be adults;
May 21: San Angelo officials inform the Texas Senate Finance Committee that the raid and its aftermath has cost more than $5.2 million, with $1.3 million accruing monthly to keep the children in custody. Status hearings in five San Angelo courtrooms cause confusion, bitterness, with little hard evidence of abuse. Texas officials return to the ranch on suspicion more children remain at the compound, are turned away for lack of a search warrant. FLDS fear another raid.
May 22: The 3rd Court of Appeals in Austin rules that Texas acted improperly in taking the children from the ranch. Judge Walther has 10 days to order return of children. CPS expected to appeal.


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Prof. Rick Aster in National Geographic, Nov. 26, 2001
In the December 2001 issue of National Geographic, Dr. Rick Aster, Earth and Environmental Science, is quoted in the lead article on Antarctica. National Geographic is one of the most widely disseminated periodicals in the world, with an English language circulation of approximately 8.6 million.
The copyrighted article begins, "Nearing the crater rim, Rick Aster paused for a warning: 'Don't try to run if it erupts. Just stand still, look up, and be ready to step aside if anything comes your way. This thing can throw lava bombs the size of a sofa.'
Aster, a geophysicist from the New Mexico Institute of Mining and Technology, issued this warning at the summit of Moutn Erebus, a massive volcano thrusting nearly two and a half miles above the Ross Sea off the coast of East Antarctica."


text: « Return to Search Dorgan Earns Norman Knight Nursing Clinical Practice Excellence Award May 30, 2014 BOSTON (May 30, 2014) – Julie Dorgan, R.N., B.S.N., a Quincy resident and an Inpatient Unit nurse at Massachusetts Eye and Ear, was recently presented with the Norman Knight Nursing Clinical Practice Excellence Award, which was established in 2002 to recognize and honor nurses whose clinical practice demonstrates excellence and a commitment to quality care. "Beloved by patients, Julie never hesitates to do what it takes to meet their needs," said Chief Nursing Officer Eileen Lowell, R.N., M.M. "Julie typically explains the tough parts of patients' treatment, and promises that things will get better. Julie often tells her patients, 'I know you're scared, but I'm on this journey with you.'" The award was presented at Mass. Eye and Ear's recent Nurses Appreciation Week Dinner, where President and CEO John Fernandez praised the organization's nurses for their "tremendous courage, professionalism and grace" in the face of many unique challenges last year, including caring for many Boston Marathon bombing victims. The appreciation and awards dinner was among the highlights of Mass. Eye and Ear's annual Nurses Appreciation Week, which offers a variety of learning opportunities and recognizes that Mass. Eye and Ear's nurses, like all employees, are an integral part of the hospital's mission. About Massachusetts Eye and Ear Mass. Eye and Ear clinicians and scientists are driven by a mission to find cures for blindness, deafness and diseases of the head and neck. Led by the Eaton-Peabody Laboratory in Otology, the Howe Laboratory in Ophthalmology and Schepens Eye Research Institute, Mass. Eye and Ear in Boston is the world's largest vision and hearing research center, offering hope and healing to patients everywhere through discovery and innovation. Mass. Eye and Ear is a Harvard Medical School teaching hospital and trains future medical leaders in ophthalmology and otolaryngology, through residency as well as clinical and research fellowships. Internationally acclaimed since its founding in 1824, Mass. Eye and Ear employs full-time, board-certified physicians who offer high-quality and affordable specialty care that ranges from the routine to the very complex. U.S. News & World Report's "Best Hospitals Survey" has consistently ranked the Mass. Eye and Ear Departments of Otolaryngology and Ophthalmology as among the top hospitals in the nation. Nurse Julie Dorgan, R.N., B.S.N., (left) receives the Norman Knight Nursing Clinical Practice Excellence Award from Chief Nursing Officer Eileen Lowell, R.N., M.M., at the hospital's recent Nurses Appreciation Week Dinner.


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Meet Annie Kong
Custodian Annie Kong has worked at De Anza for 13 years, and considers the campus her second home. "I learned English from courses that I took at De Anza," Kong says. "Consequently, I am happy working here and giving back to De Anza students and staff."
Selda Sigala-Aguilar, academic adviser in the Student Success Center, calls Kong an angel. "Annie takes such pride in keeping the Campus Center neat and clean, even though she has acquired more building space on campus to maintain," Sigala-Aguilar says, referring to the years she worked in the EOPS office. "She often checked with us to see to our needs and explained her plans for deep cleaning or shampooing the carpets when it would not interrupt our activities. Annie made an effort to get the restrooms ready for staff and students before they started their days."
Kong also helps set up outdoor events for college days and outreach activities. Despite fewer custodial staff to clean and maintain the campus and more building space to care for, Kong says she takes pride in knowing that she provides a clean environment for everyone on campus. "I hope that, through my efforts, De Anza can become a second home to everyone."


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Suffolk County Domestic Violence Affiliations
Links to Affiliations
American Bar Association Commission on Domestic Violence - Presents a directory of support services for those affected by domestic violence.
New York State Office for the Prevention of Domestic Violence - Provides information on training, technical assistance, policy development, public education and outreach links to government sites.
Suffolk County Bar Association - Provides an email link to the Bar Association, calendar of upcoming events and public services.
Suffolk County Coalition Against Domestic Violence - Provides information on legal assistance, education, employment, services, community based support groups, etc. to victims of domestic violence.
Suffolk County District Attorney's Office - Provides a listing of community resources and a directory of police precincts and federal agencies.
Suffolk County Offices - Provides a listing of Suffolk County offices including the Suffolk County Probation Department and the Suffolk County Department of Social Services.
Victims Information Bureau - Provides an overview of services for victims of domestic violence.


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Sheet music downloads have become the preferred method of acquiring classical music repertoire. Created by professional musicians, EveryNote.com presents classical sheet music download of over 20.000 popular and hard-to-find music scores over 1000 composers. A major Internet provider of classical sheet music files download online, EveryNote.com offers the largest and most complete digital sheet music download library on the Web in the world. Instantly download, view and print your favorite classical music score. Everynote.com currently offers thousands of classical music compositions for Piano, Violin, Cello, Flute, Clarinet, Classical Guitar, Voice, Chamber and Choral music.Many more instruments, composers, genres added every day! EveryNote.com has been featured in The New York Times, Globe and Mail, Musical America and many other publications.
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Internationally acclaimed Italian baritone, composer and voice teacher, Salvatore Marchesi was a professor of the Vienna Conservatory. Marchesi is the author of an important voice methodology. Marchesi translated the librettos of Tannhäuser and Lohengrin into Italian language. As a composer, Marchesi published several songs in French, German and Italian. Marchesi's Twenty Elementary and Progressive Vocalises were a direct result of his brilliant career as an artist and teacher.
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text: [solved] Problem with /usr/local/ispconfig/server/server.sh Hi there, i have multiserver setup, with mysql database server on second node. Since last upgrade to 220.127.116.11 it seems that ispconfig web interface requests are not being executed by server. When i execute /usr/local/ispconfig/server/server.sh manualy, it will gives me no output. On mysql server it will return "finished". Can someone give me an advice what should i check or so ... /var/log/ispconfig/cron.log - there are no errors at all. Thanks, Martin


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Find accommodations in Maywood with the hotel list provided below. Search for the cheapest discounted hotel and motel rates in or near Maywood, NJ for your corporate or personal leisure travel. Discover the most favored Maywood New Jersey hotel/motel rooms. Review the Maywood hotel list below to find the perfect lodging. We also have a map of the Maywood hotels. Planning a group? Lock in Maywood Group Hotel Rates
The Maywood center is approximately 1 mile southwest of The Outlets at Bergen Town Center and 1 mile southeast of Garden State Plaza.
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Tuesday, October 25 @ 5:30 p.m.
Upcoming Symposium - October 25th - Frankfort
Sunday, October 23, 2011Posted by AAGGKY at 11:50 PM
Community, Race and Memory:The Cultural Life of African Americans in Frankfort, KentuckyA Free Symposium
Tuesday, October 25 @ 5:30 p.m.
Tuesday, October 25 @ 5:30 p.m.
Labels: Community Memories, Frankfort, Grand Theatre
2 comments:
- AAGGKY said...
Wonderful event! Bringing us together, getting to know each other, telling "our" stories.
- October 28, 2011 at 12:48 PM
- Dr. Bill (William L.) Smith said...
Welcome to the GeneaBloggers family. Hope you find the association fruitful; I sure do. I have found it most stimulating, especially some of the Daily Themes.
May you keep sharing your ancestor stories!
Dr. Bill ;-)
Author of "13 Ways to Tell Your Ancestor Stories" and family saga novels:
"Back to the Homeplace" and "The Homeplace Revisited"
- October 29, 2011 at 2:49 PM
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Not to rush things, but it's about to get cold. In fact, that freezing feeling is what makes this trip to Faneuil Hall in Boston.
Just a few weeks ago what's called the "Frost Ice Bar" opened, where, you guessed it, the place is pretty much made entirely of ice.
"Everything is made of ice except the ceiling and the floor," said Grier Colella, the general manager of the Frost Ice Bar. "We have a giant swan in honor of the swan boats here in Boston . We have hanging ice. We have a chandelier and then we have a bunch of different sculptures to fill the space and make it more interesting."
Inspired by an ice bar in Stockholm, the Frost Ice Bar took about four years to finally take its frozen shape, and, inside, it's always 21 degrees.
The Frost Ice Bar at Faneuil Hall is open every day. Ticket prices vary depending on when you go, but during peak hours it's $18.99 for adults, $16.99 for seniors and students, and $6 for kids 6-12. For more information, click here to go to Frost Ice Bar website.


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Modern Art Etc.
- Location: online only
- Specialty: Emerging & Established Artists and Photographers
- Price range: $$-$$$
- Website: modernartetc.com
Store History
- Founded: November 2012
- Headquarters: Los Angeles
The folks behind Modern Art Etc. want to bring artists who have had critical and commercial success abroad to an American audience. Based in LA but operating as a web-only gallery, Modern Art Etc. is ideal for the burgeoning collector who has a few hundred bucks to drop on a rising name in the art world.
Open Modern Art Etc gallery was launched at the end of November 2012.
Inspiration for Modern Art Etc gallery's mission is to showcase artists who are winning international awards or are very collectible/established in their home countries (in the US or elsewhere), who are not yet well known in the US. For example, we are showcasing a young Chinese sculptor Xie Ai Ge who is critically recognized in Asia and Europe and is starting to be collected in the US. Her sculptures are highly sought after and collected and likely to gain more recognition in the US. We also represent several award winning US photographers where we exclusively showcase their award winning prints.
(Images: Modern Art Etc.)