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LiDa PLUS DaiDaiHua 1 Bottle
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Since the last generation of Lida DaiDaihua take 1-2 capsule / day before or after breakfast.
How Lida Capsules work.
Speed up Metabolism. Through restraining re-ingestion of norepinephrine, namely, the adrenalin B3 receptor, the brown fat tissue energy consumption is increased. Clinic experiments have proved that Dali Capsule could speed up metabolism by as high as 18 times.
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What are B3 receptors?
The B3 receptors are the most elusive and interesting of the adrenergic receptors. Studies show that these receptors are integrally involved in whole-body metabolic regulation including elevating insulin sensitivity, promoting metabolic rate, increasing size and activity of brown adipose tissue (good type of fat), and increasing fatty acid mobilization out of white adipose tissue (bad type of fat).
Control the Ingestion of Calories
Through restraining the re-ingestion of 5-HT, the hunger feeling is controlled while not influencing the normal nutrition-ingestion process. It effectively controls the ingestion of calories while the physiological needs are properly satisfied.
Safety information:
* Lida Daidaihua Slimming Capsules are not
applicable for people younger than
16 or older than 65 y.o.
* Not for women who are pregnant or breast-feeding.
* Do not take Slimming Capsules if you have high blood
pressure, cardio - vascular disease apoplexy, kidney or liver dysfunctions.
* Do not take this product LiDa DaiDaiHua
if you are taking any medications
(prescription or over - the counter)
* We always recommend before you start any diet supplements or, physical exercise programs please first consult with a physician. Accounts of research and claims about the attributes or effects of any product on this web site are for informational purposes only and should not be taken as medical advice.
How to take Lida Slimming Capsules:
* 1 capsule a day before or after breakfast.
Do not take more capsules than
* Drink more water and eat more fruit if
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blood, which causes weakness and
* Do not skip meals (especially breakfast or
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* Do not consume alcohol while taking
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Lida DaiDaihua Slimming Capsule
Product Description:
natural appetite-restraining vegetation materials (extracts) such as sweet potato fiber, cyamoposis gum powder, amor phallus konjac (extract from giant arum and jerusalem artichoke) and alfalfa.
vegetation materials (extracts) that can reduce the body fat such as tuckahoe, kola, guttiferae plant, coleus scutellarioides, guarana, marumi kumquat and trigonella foenumm, etc. - "Lida Dali"
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Usage & Dosage:
1 time/day, 1 capsule/time (before or after breakfast)
Store in cool (room temperature), dry and dark condition.
Shelf Life:
24 months
Approval Code:
KWSZ Z[2004]No. 03-0240
Lida DaiDaihua -
Pioneered by Dali scientists in Kunming, the Yunnan Province of China. " Lida Dali "
Li Da (original DaiDaiHua formula) from KmDali, is one of the best selling as compared to other natural weight loss supplements.
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Diamond Wire
In contrast to the slurry process, in diamond wire sawing the abrasive grains are fixed to the wire, which explains the alternative term 'fixed abrasive wafering' (FAW). Here, the diamond-coated wire is winded over rollers to form a wire web in the same way as for wire sawing using slurry.
Processing speed and, in turn, throughput can be greatly increased with the diamond wire process as compared to slurry technology.
Meyer Burger's diamond wire cutting technology for mono-crystalline silicon is market-leading. The extensive experience in process optimization through maximized cutting speed and minimized wire diameter at highest wafer quality is also beneficial for the process of cutting multi-crystalline silicon.
Meyer Burger's diamond wire cutting technology sets also the industrial standard for the wafering of multi-crystalline silicon.

subset: commoncrawl


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Post-Traumatic Stress
When a Navy Lieutenant who recently returned home from the Middle East is found dead from a brutal attack, the NCIS team questions the victim's friend, Marine Captain Joe Wescott (Brad Beyer, right). Gibbs (Mark Harmon, center) realizes the Captain is suffering from post-traumatic stress disorder, but knows his experience overseas may also provide a key link to the crime, in part one of a two-part episode. Pictured left to right: Michael Weatherly, Mark Harmon and Brad Beyer Photo: Richard Foreman/CBS ©2012 CBS Broadcasting, Inc. All Rights Reserved.


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The Word of Wisdom is for our physical and spiritual benefit.
What is the Word of Wisdom?
The Word of Wisdom is a law of health revealed by the Lord for the physical and spiritual benefit of His children. On February 27, 1833, as recorded in section 89 of the Doctrine and Covenants, the Lord revealed which foods are good for us to eat and which substances are not good for the human body. He also promised health, protection, knowledge, and wisdom to those who obey the Word of Wisdom.
In the Word of Wisdom, the Lord revealed that the following substances are harmful:
Alcoholic drinks (see D&C 89:5-7).
Tobacco (see D&C 89:8).
Tea and coffee (see D&C 89:9; latter-day prophets have taught that the term "hot drinks," as written in this verse, refers to tea and coffee).
When people purposefully take anything harmful into their bodies, they are not living in harmony with the Word of Wisdom. Illegal drugs can especially destroy those who use them. The abuse of prescription drugs is also destructive spiritually and physically.
The Lord also declared in the Word of Wisdom that the following foods are good:
Vegetables and fruits, which should be used "with prudence and thanksgiving" (see D&C 89:10-11).
The flesh "of beasts and of the fowls of the air," which is "to be used sparingly" (see D&C 89:12-13).
Grains such as wheat, rice, and oats, which are "the staff of life" (see D&C 89:14-17).
To those who keep the Word of Wisdom, the Lord promised:
"All saints who remember to keep and do these sayings, walking in obedience to the commandments, shall receive health in their navel and marrow to their bones;
"And shall find wisdom and great treasures of knowledge, even hidden treasures;
"And shall run and not be weary, and shall walk and not faint.
"And I, the Lord, give unto them a promise, that the destroying angel shall pass by them, as the children of Israel, and not slay them" (D&C 89:18-21).
The best course is to completely avoid the substances that the Lord prohibits in the Word of Wisdom. Those who have engaged in addictive behaviors can stop and become free from addiction. Through personal effort, strength from the Lord, help from family members and friends, and guidance from Church leaders, anyone can overcome addiction.
See also Obedience; Temptation
—See True to the Faith (2004), 186-88
See also the "What We Believe" article "The Lord Has Given Us a Law of Health," Liahona, Feb. 2012, 12.


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About the Alliance of Rouge Communities (ARC)
The Alliance of Rouge Communities (ARC), a 501(c)(3) organization, is a voluntary public watershed entity currently comprised of 35 municipal governments (i.e. cities, townships and villages), three counties (Wayne, Oakland and Washtenaw), Henry Ford Community College, University of Michigan-Dearborn and cooperating partners (i.e. other organizations) as authorized by Part 312 (Watershed Alliances) of the Michigan Natural Resources and Environmental Protection Act (MCL 324.101 to 324.90106) as amended by Act No. 517, Public Acts of 2004.
The purpose of the ARC is to provide an institutional mechanism to encourage watershed-wide cooperation and mutual support to meet water quality permit requirements and to restore beneficial uses of the Rouge River to the area residents.
Current and recently completed projects include:
- 2018 USEPA funded habitat design projects in AOC - Tamarack Creek in Southfield and Johnson Creek Fish Hatchery in Northville
- 2017 GLRI USDA Forest Service Restoring Tree Canopy in the Rouge River - Learn more about the project
- 2016 USEPA funded Henry Ford Estate Dam Fishway Construction - Learn more about the project, EPA announcement
- 2016 USEPA funded Oxbow Phase III Construction - Learn more about the project, EPA announcement
- 2015 GLRI NOAA funded Henry Ford Estate Dam Fishway design project - Learn more about the project
- Storm Water, Asset Management and Wastewater (SAW) Grant Program
- 2014 Restoring Tree Canopy in the Rouge River Area of Concern funded through GLRI and USDA Forest Service - Learn about the Project, View the Grant Final Report
- 2013 Rouge Oxbow Restoration Project Phase III Design funded through Great Lakes Restoration Initiative (GLRI) and National Oceanic and Atmospheric Administration (NOAA) - Learn about the project, Learn what the benefits will be
- 2012 Restoring Community Trees in an Urban Watershed funded through
GLRI and USDA Forest Service - Learn about the project
- Danvers Pond Dam Removal funded through GLRI
- Transforming the Rouge funded through GLRI
- Wayne Road Dam Removal and Restoration funded through a Rouge Round X Grant, GLRI and NOAA
- Rouge River Monitoring for E. coli TMDL Implementation funded through MDEQ Clean Water Fund (CMI)
Health of the Rouge River


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Only hotels in 33762 zip code are listed below. Search for cheap and discount hotel rates in Clearwater, FL for your upcoming leisure or conference / group travel. We list the best 33762 hotels and motels so you can review the Clearwater hotel list below to find the perfect lodging. Hotels in Pinellas county and area code 727 are also listed.
How should we direct your call?


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NORTHFIELD, Vt.—Ryan Smith scored 3:18 into overtime to cap off a two-goal rally and help launch Babson College to the ECAC East Championship Game with a 4-3 win over UMass Boston Friday night at the Kreitzberg Arena.
With the loss, #11/11 UMass Boston ends their second-best season in program-history at 19-6-2. The Beacons experience a historic season, earning an eight-week run in the national polls and their highest conference finish in over two decades.
It just wasn't enough against third-seeded Babson College, who moved to 16-6-5. The #12/13 Beavers will play in their fourth ECAC East Championship Game in five years, when they take on #1/1 Norwich University Saturday night at 7 p.m.
The loss marks the end of five seniors' careers at UMass Boston: Mike DeGrazia (Novi, Mich.), Steve Weston (Henniker, N.H.), Tim Niedzielak (Chicago, Ill.), Tim Richter (Naugatuck, Conn.) and Rob Florentino (West Roxbury, Mass.). The class of 2013 ends their career with 58 victories and one of just four UMB classes with a Codfish Bowl Championship.
Friday night's game was defined by two quick flurries of goals that completely flipped the momentum.
After failing to score for the first 31 minutes, UMass Boston turned the tide, with back-to-back-to-back goals from Richter, Mark Grinhaus (Scarsdale, N.Y,) and Kit Sitterley (Mooresville. N.C.) within a 47-second span to grab a 3-1 lead.
With the Beacons holding all the momentum and less than five minutes to go in regulation, the Beavers struck for two goals within 28 seconds to tie the game and force overtime.
While the offenses struggled to gain any kind of momentum outside of those two periods, both goaltenders played tremendous games.
Freshman Zach Andrews (Coral Springs, Fla.) made 32 saves on 36 shots for the Beacons to finish his freshman season 17-6-2. The freshman netminder made 27 saves over the first two periods, including 15 in the first, to keep his team in the game. He finishes his freshman season with the most wins in a single season (17), the second most games played (25) and the third most minutes played (1478:57).
On the other side, ECAC East Goalie of the Year Zeke Testa made 30 saves on 33 shots, including 13 in the third period.
Babson College dominated the first half of the game by using a blue-line trap that consistently stymied the Beacons efforts to setup anything offensively. With UMass Boston continually turning the puck over at center ice or just inside the Beacons end, the Beavers piled up a 21-11 shot advantage and scored the lone goal of the first 30 minutes.
Matt O'Neill made it 1-0 Babson with a power-play goal at the 9:52 mark, when he took a rebound off of a Ben Kravitz shot and sent a backhand look past Andrews.
The Beacons slowly turned the tide in the first five minutes of the second, as they began passing the puck more efficiently and spreading out the Babson defense.
UMass Boston's patience finally paid off at the 11:39 mark, when Richter rammed home a Derek Colucci (North Scituate, R.I.) rebound to tie the game at 1-1. Grinhaus made it 2-1 UMB at the 12:17 mark when DeGrazia skated hard towards the net and dished it off to a cutting Grinhaus, who lifted the puck into the top left-corner. Sitterley capped off the scoring seconds later, when he won an offensive zone faceoff and immediately sent a backhander over the shoulder of Testa.
With all the momentum going their way, UMass Boston dominated play over the next 20 minutes, racking up a handful of Grade A chances and nearly 20 shots. The Beacons looked as if they were going to put it away with six minutes to go when Babson was called for their first penalty of the night, but the UMB power-play backfired.
Babson pinned the Beacons special teams unit in their own end and made it 3-2 just seven seconds after the man-advantage expired. Mike Driscoll took a pass from Jared Wiedemann and sent a shot off of Andrews pads that just barely trickled across the goal line at the 15:31 mark of the period.
Jay Haseley tied the score with 4:01 to go in regulation, when he skated in on a 3-on-2 rush and sent a high shot over Andrews shoulder to make it 3-3.
UMass Boston skated with renewed vigor over the final four minutes and had a handful of good chances but couldn't beat Testa.
After a 15-minute intermission, Smith made the Beacons pay 3:18 into the extra session. The senior captain found a Matt Furey rebound that never made it to Andrews and fired a shot high over Andrews' pads to send the Beavers back to the title game.


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The NFL has announced sweeping changes to the Pro Bowl. The biggest change comes from the elimination of the conference affiliations and picking teams from the 86 players who make it to Hawaii.
The overall Pro Bowl rosters will continue to be determined by the fans, coaches, and players. And two fans will indeed be directly involved in shaping the final configuration of players.
"One of these champions will earn their spot as part of Lenovo's Fantasy Coach of the Year program, which provides NFL.com fans a chance to be rewarded for their fantasy football skills," the league's release announcing the changes explains. "The other champion can compete for a Pro Bowl role by playing at NFL.com/fantasy."
Each team will be determined by a three-person collaboration — a former player (this year, Jerry Rice or Deion Sanders), one of the highest vote-getters on offense or defense from the Pro Bowl rosters, and one of the two fans.
The Pro Bowl player draft will be televised by NFL Network on Wednesday, January 22. The teams then will practice on Thursday, Friday, and Saturday. The game will be played on Sunday, January 26.
The new approach reflects verbatim the contents of the fan survey previously posted at NFLHuddle.com. While there's no guarantee it will make the game more interesting, it can't make it any more uninteresting.


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Director Michael Haneke's acclaimed drama 'Amour' has been given a big Oscar boost after picking up the Film of the Year prize at the 33rd London Critics' Circle Film (LCFF) Awards.
The film, which was nominated for five Academy Awards including Best Picture and Best Director earlier this month, beat out "The Master" to claim the coveted trophy at a gala held at London's Mayfair Hotel on Sunday night.
Haneke also picked up a screenplay award and his leading lady, French actress Emmanuelle Riva, was named Best Actress.
The filmmaker lost out to "Life of Pi's" Ang Lee in the Best Director category.
"The Master" was a double winner at the LCCF Awards – co-stars Joaquin Phoenix and Philip Seymour Hoffman picked up the Best Actor and Best Supporting Actor honors respectively. Anne Hathaway won Best Supporting Actress for her role as a singing prostitute in "Les Miserables" and Jacques Audiard's "Rust and Bone" claimed the Best Foreign Language Film.
Other winners included "The Imposter" (Best Documentary), "Berberian Sound Studio" (Best British Film), Toby Jones (British Actor of the Year), Andrea Riseborough (British Actress of the Year) and "The Impossible's" Tom Holland (Young British Performer of the Year).
Meanwhile, the LCCF's top 10 films of 2012 were "Amour," "The Master," "Life of Pi," "Argo," "Beasts of the Southern Wild," "Zero Dark Thirty," "Once Upon a Time in Anatolia," "Django Unchained," "Tabu" and "Rust and Bone."
Their highest honor, the Dilys Powell award for excellence in film, was presented to actress Helena Bonham Carter by director Mike Newell.


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Hubble's Largest Galaxy Portrait Offers a New High-Definition View
Giant galaxies weren't assembled in a day. Neither was this Hubble Space Telescope image of the face-on spiral galaxy Messier 101 (M101). It is the largest and most detailed photo of a spiral galaxy that has ever been released from Hubble. The galaxy's portrait is actually composed of 51 individual Hubble exposures, in addition to elements from images from ground-based photos. The final composite image measures a whopping 16,000 by 12,000 pixels.
The Hubble archived observations that went into assembling this image were originally acquired for a range of Hubble projects: determining the expansion rate of the universe, studying the formation of star clusters in the giant star birth regions, finding the stars responsible for intense X-ray emission, and discovering blue supergiant stars.
The giant spiral disk of stars, dust, and gas is 170,000 light-years across or nearly twice the diameter of our galaxy, the Milky Way. M101 is estimated to contain at least one trillion stars. Approximately 100 billion of these stars could be like our Sun in terms of temperature and lifetime.
The galaxy's spiral arms are sprinkled with large regions of star-forming nebulae. These nebulae are areas of intense star formation within giant molecular hydrogen clouds. Brilliant young clusters of hot, blue, newborn stars trace out the spiral arms. The disk of M101 is so thin that Hubble easily sees many more distant galaxies lying behind the galaxy.
M101 (also nicknamed the Pinwheel Galaxy) lies in the northern circumpolar constellation, Ursa Major (The Great Bear), at a distance of 25 million light-years from Earth. Therefore, we are seeing the galaxy as it looked 25 million years ago - when the light we're receiving from it now was emitted by its stars - at the beginning of Earth's Miocene Period, when mammals flourished and the Mastodon first appeared on Earth. The galaxy fills a region in the sky equal to one-fifth the area of the full moon.
The newly composed image was assembled from Hubble archived images taken with the Advanced Camera for Surveys and the Wide Field and Planetary Camera 2 over nearly 10 years: in March 1994, September 1994, June 1999, November 2002, and January 2003. The Hubble exposures have been superimposed onto ground-based images, visible at the edge of the image, taken at the Canada-France-Hawaii Telescope in Hawaii, and at the 0.9-meter telescope at Kitt Peak National Observatory, part of the National Optical Astronomy Observatory in Arizona. The final color image was assembled from individual exposures taken through blue, green, and red (infrared) filters.
For more information, please contact:
K.D. Kuntz, Goddard Space Flight Center, Baltimore, Md.,
(phone) 301-286-1301, (e-mail) firstname.lastname@example.com or
Ray Villard, Space Telescope Science Institute, Baltimore, Md.,
(phone) 410-338-4514, (e-mail) firstname.lastname@example.com or
Soren Larsen, ESA/Space Telescope European Coordinating Facility,
European Southern Observatory, Garching, Germany,
(phone) 011+4989-3200-6576, (e-mail) email@example.com or
Lars Lindberg Christensen, Hubble/ESA, Garching, Germany,
(phone) 011+49-89-3200-6306, (cell phone) 011+49-173-3872-621, (e-mail) firstname.lastname@example.com
Credit for Hubble Image: NASA, ESA, K. Kuntz (JHU), F. Bresolin (University of Hawaii), J. Trauger (Jet Propulsion Lab), J. Mould (NOAO), Y.-H. Chu (University of Illinois, Urbana), and STScI;
Credit for CFHT Image: Canada-France-Hawaii Telescope/ J.-C. Cuillandre/Coelum;
Credit for NOAO Image: G. Jacoby, B. Bohannan, M. Hanna/ NOAO/AURA/NSF


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Hello. This is the 2013
Hello all and in particular America. I shall no doubt upset a few here but comments on this subject would be most interesting and in particular considering that in the twenty-first century we do have electricity and batteries and for a very small amount of money, a scale can be purchased. A scale is accurate and leaves nobody in doubt as to the quantities required be it ounces or metric. So the question here is why do so many people in the business of food formulas (in America) insist on displaying ingredients is something so variable as a cup. The bottom diameter can be different to the top and marking the height into eights or tens is ridiculous. Add to that, compaction and it gets worse. Same with spoons.
Further, in the case of those that write recipe books that are supposed to sell to the international market makes the situation even more farcical and almost leave me with the feeling, stuff every one else, do as we do. Personally, I would never purchase a book that was written without a SENSIBLE weights and measurement system. That's it, off my chest. Still love TFL.


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Cutting into Planet Layers
January 28, 2007
NASA's powerful Hubble Space Telescope has allowed astronomers to study for the first time the layer-cake structure of a planet orbiting another star. .
Rosetta Locks on Target
January 28, 2007
ESA's Rosetta spacecraft has caught its first glimpse of an asteroid it will be studying later during its primary mission.
Starlight Meteorology
January 26, 2007
Observations of Saturn's moon Titan from earth-based telescopes played a vital role in the successful decent of the Huygens probe through Titan's thick atmosphere in January of 2005.
Opening an Eye to the Stars
January 26, 2007 The COROT telescope has successfully opened its protective cover and began gazing at the stars.
Huygens's Second Landing Anniversary
January 16, 2007 Two years ago, scientists accomplished an amazing feat when the Huygens probe descended through the thick atmosphere of Titan to reveal the moon's unique surface.
Swooping Under the Sun
January 10, 2007
The Ulysses spacecraft has reached maximum latitude in its exploration of the heliosphere, the bubble in space blown out by the solar wind.
Water Flows Today on Mars
December 7, 2006
Water could recently have flowed on the Martian surface. ESA's Mars Express joins the hunt for evidence.
Rocky Worlds
November 3, 2006
COROT space telescope set to search out small, rocky extrasolar planets.


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News & Events
For the Media
Clarkson University Professor S.V. Babu Prepares Students for Global Workforce
40 Ph.D. Graduates, So Far
S.V. Babu of Clarkson University, director of Clarkson's Center for Advanced Materials Processing (CAMP), is internationally renowned in a cutting-edge field of semiconductor device processing, but students come first in his heart.
Advising and guiding students is something that Distinguished University Professor Babu does exceptionally well. This October, he reached a new milestone when his 40th Ph.D. student, John Bogere Matovu, successfully defended his doctoral thesis, "Chemical Mechanical Polishing of InP, GaAs, and InGaAs Films and Related Environment and Safety Aspects." Matovu has already moved to Boise, Idaho, where he had a position with Micron Technology waiting for him.
"It's my responsibility to prepare them to go out into the world and succeed," Babu says of his students. "It's very satisfying to see the young students in their twenties come in here and struggle to learn at first, but then leave with cutting edge technical expertise for jobs where they will be valued and appreciated by the companies that hire them."
Those companies include IBM, Intel, Micron, Xerox, Dow, Corning and others. The corporations provide crucial financial support for project-based research and seem to hire the students as quickly as Clarkson and Babu can prepare them.
"They're working on the frontiers of knowledge, of technology and of business that are all moving very fast and becoming increasingly global. Our role at the University is to enable them to learn fast, to synthesize what they learn in the lab with what the industry needs and values. They work amid global competition," he emphasizes.
The professor, who joined the faculty of Clarkson in 1981, became the director of the New York State-supported Center for Advanced Materials Processing in 1999. A chemical engineer with a Ph.D. in physics, his research covers interdisciplinary areas spanning materials processing and chemical mechanical planarization for microelectronic device fabrication. Simply put, this work involves smoothing or polishing material surfaces to the nanoscale level necessary to build computer logic and memory chips and related devices.
"The number of applications for such devices keeps growing -- computers, cell phones, digital cameras, even sophisticated movie animation," Babu says. "We take this (computer chip) technology for granted now because it works so well."
The technology also keeps developing, so the Clarkson students and their peers must keep their knowledge and skills honed. That's another area where the teacher sets the example. Babu has 28 patents issued and is a coauthor of more than 250 professional publications. Also, he has helped organize many symposia and delivered keynote talks at many conferences. He is a recipient of the 2004 IBM Faculty Award and was honored in 2010 with a Visiting Professorship for Senior International Scientists by the Chinese Academy of Sciences. Last year, he received an Education Leadership award from the World Education Congress held in Mumbai, India.
The professor passes that imprint of expertise and diligence on to his students. Consider the numbers. Over his career so far, he has supervised 77 graduate students. Five of his doctoral students and six of his 37 M.S. degree students completed their work at the Indian Institute of Technology in Kanpur. The others finished their degrees at Clarkson University.
"It's very rewarding to help send them out to do well for themselves and in their careers," he says.
Clarkson University launches leaders into the global economy. One in five alumni already leads as a CEO, VP or equivalent senior executive of a company. Located just outside the Adirondack Park in Potsdam, N.Y., Clarkson is a nationally recognized research university for undergraduates with select graduate programs in signature areas of academic excellence directed toward the world's pressing issues. Through 50 rigorous programs of study in engineering, business, arts, sciences and health sciences, the entire learning-living community spans boundaries across disciplines, nations and cultures to build powers of observation, challenge the status quo, and connect discovery and engineering innovation with enterprise.
Photo caption: Above, Professor S.V. Babu's research and lab group. Front row: Prof. Panart Khajornrungruang, John Matovu, Kaushik Varma Sagi and Ted Champagne. Middle row: Prof. Jun Li, Sevim Korkmaz, Yoichi Fujieda, S.V. Babu, Leila Boyea and Kelly Covert. Back row: Cong Fu, Prof. Zifeng Ni, Uma Lagudu and Chris Plunkett.
[A photograph for media use is available at http://www.clarkson.edu/news/photos/babu-group-2013.jpg.]


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July 16,2014(ISN) – The Toronto Blue Jays Baseball Academy in conjunction with Honda Canada and Whitby
Minor Baseball Association will host a one day Honda Super Clinic on Sunday, July 20
at Iroquois Park in Whitby, Ontario. The clinic will serve as a fundraiser for the
Selective Dorsal Rhizotomy (SDR) surgery for 8 year old Ben Sheppard from Whitby.
The clinic is sold out, with more than 420 players registered.
To date, more than $68,000 has been raised through clinic registrations fees and a
matching financial contribution from Honda Canada. With additional funds raised by
the Sheppard family, the Blue Jays are pleased to announce the $100,000 fund raising
goal has been met. Ben Sheppard will receive his surgery.
Each participant attending the clinic will receive a Blue Jays t-shirt, Blue Jays
Cap, and a Roberto Alomar 12 inch Pro Model baseball glove. Instructors will be
Blue Jays Alumni: Roberto Alomar, Alex Gonzalez, Tony Fernandez, Devon White, Lloyd
Moseby, George Bell, Jesse Barfield, Carlos Delgado, Brian McRae, Duane Ward, and
Nigel Wilson. The Blue Jays alumni will be donating their time to help with this
The Clinic will run from 9:00am-12:00pm, with a cheque presentation happening at
noon. Interested members of the media are encouraged to attend the last hour of the
clinic along with the cheque presentation at noon. Whitby Oshawa Honda will be
hosting a post clinic barbeque for the 420 participants and family.
In addition, six Durham Region Boston Pizza restaurants will be donating 10% of any
bill that has "BEN" written on the back of it on Sunday July 20. Participating
restaurants located at 1899 Brock Road in Pickering, 8 Salem Road South in Ajax, 75
Consumers Drive in Whitby, 20 Taunton Road East in Whitby, 2372 Highway 2 in
Bowmanville, and 951 Taunton Road East in Oshawa.
About Ben Sheppard:
Ben Sheppard is eight years old and loves everything baseball. His favourite team is
the Toronto Blue Jays and his dream is to play on the big field one day; running the
bases and catching balls like his heroes.
Ben was adopted at the age of 5 and lives with left hemiplegic spastic cerebral
palsy. This condition causes a lot of tightness and spasticity in Ben's muscles,
particularly on his left side. As a result, Ben experiences many challenges
participating in daily activities that many of us take for granted; even something
as simple as walking is a constant challenge for Ben.
As Ben gets older his ability to move is deteriorating. The tightness in Ben's
muscles is preventing his bones from growly properly. This is very uncomfortable for
Ben and often very painful. As a result Ben frequently falls and has been relying on
his wheelchair to get around. In order to improve Ben's quality of life, he needs a
surgery called Selective Dorsal Rhizotomy (SDR). SDR is a relatively new surgery
performed by the highly skilled, Dr. T.S. Park, most effectively at the St. Louis
Children's Hospital. This surgery will release some of the tightness and spasticity
in Ben's muscles, which will allow him to move around more freely.


text:
(Simply send me a message if you would like to order one! email@example.com.)
Textile design and sewing by yours truly.
(Oh, and i must add - i accidentally didn't order enough fabric, so that's why the print on the last two skirts finish early and theres a white gap. whoops! Won't be making that mistake again.)


text:
Studied Four Species of Crustaceans
- Cancer irroratus
- Cancer borealis
- Uca Pugilator
- Homarus americanus
Microdissection (removal of neural tissue)
- Eyestalks
- Pericardial Organs
- Somatogastric Nervous System
- Brain
- Cardiac Ganglion
MEL in Crustaceans (and other invertebrates)
- Melatonin produced in crustacean eyestalks
- Similar physiological and behavioral roles
- Invertebrate receptors not yet studied
- May have conserved role in cellular functions such as neurite growth
X-organ Cells:
- Ease of culture
- Similarity to vertebrate neurons
- Survive and grow up to 7days
- Multipolar
- Neurosecretory (like vertebrate hypothalamus)
Sinus Gland
Purpose and Goals
- To identify areas of the crustacean nervous system with antidieuretic hormone, melatonin, and melatonin receptors
- To learn techniques such as microdissection, cell culture, brightfield microscopy, fluorescence microscopy, confocal microscopy, and image analysis.
- To apply these techniques to a collaborative group project.
- To gain expertise in an area of neuroscience research; to design and conduct a research project; to analyze, interpret, and present results.
- To construct and update this website as an informative and instructive tool for the course.
- To gain scientific skills in microdisection, immuncytochemistry, immunohistochemistry, flourescence and brightfield microscopy, confocal microscopy
Potential Clinical Implications
- Neurodegenerative Diseases: Alzheimer's, Parkinson's, ALS
- Axonal Regeneration
- Nervous System Repair
- Nerve damage, Paralysis
To anesthetize crustaceans for dissection, place them on ice for 25-45 minutes. To begin dissection, first remove all limbs and mouth parts from the animal. Next, use 'crushers' to break the shell around the outer edge, being careful not to get too close to the eyestalks. Use the scraper to gently separate the muscle from the inside of the shell. Break the shell away from the body in order to free the face of the crustacean. Use the scraper again to separate the muscle from the bottom shell, focusing on the area near the eyes and exposing the two thin gastric muscles just below the eyes. Then use large scissors to separate the eyestalks and surrounding shell from the rest of the crab (making sure to cut laterally). Place the eyestalks into crab saline and put them in a refrigerator until you are ready to dissect them.
Using the forceps, gently hold the start of the esophagus, which can be found right under the eyestalks that were just removed. As you hold the esophagus in one hand, in the other use a small pair of scissors to separate the stomach from the rest of the crab, ending the dissection at the end of the pylorus. Once the stomach is removed, gently rinse it with crab saline and then use the scissors to cut through the stomach following the esophagus to the pylorus. On the end opposite of the esophagus, make two butterfly cuts diagonally from main cut in order to allow the stomach to lie flat. Using the small scissors, remove the three teeth from the stomach, and then pin it in a dissecting dish with the side that once had the teeth face down. Gently pour enough crab saline to cover the stomach and then place the dish in the fridge until dissection.
Pericardial Organ (P.O.)
After removing the stomach, use the scissors and the scraper to separate the tissue from the remaining shell, and then remove the shell altogether. With a large pair of scissors, cut off the rounded sides of the crab (both left and right) and remove the gills. Using a scraper, gently remove the rest of the crab parts left in the body cavity. Next, using a large pair of scissors cut down the center of the crab, separating the left from the right. Place both parts in saline and put them in the fridge until you are ready to dissect them.
Crab dissection
Stomach fully isolated from crab
After removing the eyestalks from the fridge, use the scissors to cut down middle between the two eyes, separating them. Gently remove the excess shell from around both eyes, until they are free. Holding the eye in one hand, use a small pair of scissors to make an incision from the base of the eye stalk up through the retina. Make an identical incision on the opposite side of the eyestalk, and repeat for the other eye (note: each eyestalk should still be in one piece when you are finished). Place each eyestalk in a dish with crab saline for dissection and use a dissecting microscope for the remainder of the dissection. Under the microscope use a pair of dissecting forceps and scissors to remove the eye tissue from the outer shell. The sinus gland can be identified by its brighter white or sometimes opal color. Remove the majority of the unwanted tissue, making sure to keep some tissue surrounding the sinus gland and parts of the retina and optic nerve for orientation. It is important to change the saline every 15-20 minutes in order to keep the sample cool and remove excess tissue in the solution. When the dissection is complete, fill a new dish with crab saline. Using forceps, gently place the dissected eyestalk into the new dish and pin it down. Cover the dish, and using tape, label the dish with the date, genus, species and sex of the organism, and the type of tissue.
Remove the stomach from the fridge and continue the dissection under the microscope. On the esophagus end, locate the brain of the crustacean. Gently follow the nervous tissue eradiating from the brain and using a pair of dissecting scissors separate the brain from the rest of the tissue making sure not to remove too much nervous tissue. Place the brain in a clean dish with crab saline, pin it down, cover it, and label it according to the previous system. Back at the stomach, near where the brain was removed, there should be more nervous tissue. Remove the commissural ganglion (COG), the oesophageal ganglion (OG), the stomatogastric ganglion (STG), and surrounding nervous tissue (see picture more detail). Place the stomatogastric nervous system (STNS) in a clean dish with saline, carefully pin it, then cover and label it.
Remove one pericardial organ from the fridge, place it in a deep dissecting dish with enough crab saline to cover the entire thing and put it under the microscope. The P.O. is typically located in a small hole on the part of the tissue that would have faced the inside of the crab. With the part of the tissue where the limbs once were face down in the dish, the aforementioned hole should be in the lower center part of the tissue. Remove the pericardial organ (with as little tissue on it as possible) using dissecting forceps and scissors, making sure to include both nerve bars.
Close-up view of crab eye
P.O., ready for microdissection
A carefully pinned STNS
Fluorescence and brightfield microscopy
After mounting, we waited an appropriate amount of time for the slides to dry. All slides were initially looked at under a Zeiss Axiovert 200 fluorescence microscope. We viewed a total of 59 stained slides under the fluorescent microscope and chose selected slides to be imaged in more detail using an Olympus Fluoview 1000 confocal microscope.
Confocal microscopy
After locating the area of interest on each slide using regular fluorescence and brightfield microscopy we used the confocal imaging software. To optimize the image we adjusted the focus, offset, voltage, and gain. To generate the images below we used a Kalman filter to minimize background noise and a longer exposure time to obtain high quality images. We additionally took Z stacks of the slides in order to view a 3D perspective of the tissue.
C. borealis eye (near retina) and pericardial organ labeled with DH, respectively
2009 Class Group
Jan Plan 2009 - Advanced Neurobiology BI474
Course Goals:
- To learn techniques such as microdissection, cell culture, brightfield microscopy, fluorescence microscopy, confocal microscopy, and image analysis.
- To apply these techniques to a collaborative group project.
- To gain expertise in an area of neuroscience research; to design and conduct a research project; to analyze, interpret, and present results.
- To construct and update this website as an informative and instructive tool for the course.
Crustacean X-organ cell with neurites, 400x, Phase
Lola the Microscope, Funded by INBRE-Maine
Mount Desert Island Biological Laboratory:
Jackson Laboratory: We also toured the
More MDIBL Pix:
[Above] MDIBL Coop
[Above] Christina, Jen, Ruthie, Kimberly, Ben, Sharonda, Vic,
Other Laboratory Activities:
Tilden Research Page
- 1. BI474 Protocols
- 2. General Laboratory Technique Links
- 3. Microscopy Links
- 4. Neurite Growth Research Project-JanPlan 2009
- Amy's babies
- Benwants8children.com
- Christina's Toodlers
- cool youtube video about neuron degeneration and metals
- Kimberly's Offspring
- My name is Vic- I like Neurons.
- Sharonda's Chillins
- Spring 2010 - BI474 Advanced Neurobiology


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Item 12 of 12
Map of Fort Land, Brunswick, 1763Item 11454 info
Maine Historical Society
©2000-2019 Maine Historical Society, All Rights Reserved.
Many images on this website are for sale on
The Maine Memory Network is a project of the Maine Historical Society.
Except for classroom educational use, images and content may not be reproduced without permission.


text:
It was used in Mel Brooks' Spaceballs, in the Schwarzenegger movie Total Recall and in countless sci-fi books and movies: some kind of anatomy-based identification. Usually it involves hand- or fingerprint ID, or sometimes a scan of the eyeball, but whatever it is gains access to a secret room.
Never has a person's posterior, that I know of, been used as a way to verify identity.
Researchers in Japan, though, think they've figured out a way, and the application could end up in the driver's seats of Japanese-made cars sooner than you'd think.


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Dave Wassel is nominated in the Monster Paddle category.
The nominees have just been announced for the 2012 Billabong XXL Global Big Wave Awards fueled by Monster Energy, and the surfing community is bracing for another epic showdown of the biggest waves and greatest rides witnessed worldwide over the last year.
The 12 months leading up to the end of the annual XXL cycle at the end of the Northern Hemisphere spring on March 19 have been widely regarded as the most spectacular ever seen in the sport of big wave riding. "Biggest-ever" swells were conquered at surf breaks in locations ranging from Tahiti to Ireland and from Tasmania to Portugal along with "just plain huge" days in Mexico, Fiji, California and Hawaii. When whittled down to the top five nominees in each of the XXL's seven divisions, every category is filled with breathtaking moments, all worthy of being named an XXL champion and each with a shot at a share of the $120,000 in prize money at stake. To view all the nominated rides, please see the event website at www.BillabongXXL.com.
The winners will be announced at the invitation-only Billabong XXL Big Wave Awards party at the Grove Theater in Anaheim, California on May 4, 2012. The show will be webcast that night on YouTube's Newtork A, and will be broadcast as a one-hour program on FUEL TV on Sunday, May 20 at 3 P.M. PT. This year's event marks the 12th-annual edition of the Billabong XXL Big Wave Awards, an event open to every qualified surfer at every break on every day of the year, so long as the action is captured by a video or still camera and submitted for judging by the XXL's voting academy of expert surfers and lensmen. Over 1,000 images were entered into the event before being filtered down to the best five stills and single definitive video clip of each nominated ride.
In the all-important Billabong XXL Ride of the Year category, there are five very different waves in contention, all ridden in very different regions around the planet. In consideration for the $50,000 winner's prize are a pair of Southern Californians: Nathan Fletcher for his earth-shattering barrel at Teahupoo, Tahiti and Greg Long for his paddle-in tube at Puerto Escondido, Mexico. Two Australians are also represented, including Ryan Hipwood for his long, spitting pipe of a wave at Cloudbreak,Fiji and upstart Jeff Rowley for a hair-raising late paddle drop and pocketride at Jaws on Maui (a spot generally believed to be a tow-surfing-only location prior to the last two winters). Rounding out the five is the lone Hawaiian, Garrett McNamara, for his plunge into a massive face off the coast of Portugal, a feat that earned the big wave veteran global headlines in November.
The ride of the year nominees
[poll id=21]
The theme of recent years to push the envelope of what is possible in the realm of arm-powered surfing has continued unabated with another slate of stunning nominees in the highly-regarded Monster Paddle division. Earning spots as finalists for 2012 are: Santa Cruz's Ken "Skindog" Collins at Maverick's near San Francisco, California; Australian Jamie Mitchell at Todos Santos Island off Ensenada, Mexico; and Brazil's Danilo Couto, Oahu's Dave Wassel and Big Islander Shane Dorian all being recognized for man-handling huge, windy walls at Jaws, on the north shore of Maui.
The five Monster Paddle rides
[poll id=23]
In the XXL Biggest Wave category (open to waves caught with jet skis or any other means), another five rides are being honored for maximum height — pure andsimple. McNamara is nominated once more for his Portugal ride, which will be compared to two dark and frigid late-season Irish giants ridden at Mullaghmore Head by local Ollie O'Flaherty and the UK's Andrew Cotton. Adding to the European domination of the Biggest Wave division this year is a clean, green ride by Basque surfer Axi Muniain at Agiti, on the northern coast of Spain. Joining the four Euro Zone rides is a beautiful big blue bomb of a wave at Cow Bombie in Western Australia, precisely ridden from start to finish by W.A.'s own Damien "Taco" Warr.
The XXL finalists
[poll id=25]
Nominees have also been announced for the Monster Tube Award. All the surfers, photographers and videographers are listed below and all the nominated still and video images can be viewed at the event website at www.BillabongXXL.com
The nominees for 2012, in alphabetical order:
(Surfer prize $50,000 – Video prize $5,000)
Nathan Fletcher (San Juan Capistrano, California, USA) at Teahupoo, Tahiti on August 27, 2011.
(Video by Simon Saffigna.)
Ryan Hipwood (Gold Coast, Australia) at Cloudbreak, Fiji on July 12, 2011.
(Video by Nimai Strickland.)
Greg Long (San Clemente, California, USA) at Puerto Escondido, Mexico on May 19, 2011.
(Video by Alejandro Berger.)
Garrett McNamara (Haleiwa, Hawaii, USA) at Praia do Norte, Nazaré, Portugal on November 1, 2011.
(Video by Jorge Leal.)
Jeff Rowley (Torquay, Victoria, Australia) at Jaws, Maui, Hawaii on January 30, 2012.
(Video by Wangdu Hovey.)
(Surfer prize $15,000 – Photo/video prize $4,000)
Ken "Skindog" Collins (Santa Cruz, California, USA) at Maverick's, California on February 8, 2012.
(Photos by Robert Brown and Frank Quirarte. Video by The Go Big Project.)
Danilo Couto (Bahia, Brazil) at Jaws, Maui, Hawaii on January 4, 2012.
(Photo by Fred Pompermayer. Video by Greg Browning.)
Shane Dorian (Kona, Hawaii, USA) at Jaws, Hawaii, on January 4, 2012.
(Photos by Bidu, Tracy Kraft, Bruno Lemos, Jason Murray and Fred Pompermayer. Video by Elliot Leboe.)
Jamie Mitchell (Gold Coast, Australia) at Todos Santos, Mexico on January 6, 2012.
(Photo by Jason Murray. Video by Graham Nash.)
Dave Wassel (Haleiwa, Hawaii, USA) at Jaws, Maui, Hawaii on January 4, 2012.
(Photos by Eric Aeder, Frank Berthuot, Bruno Lemos, Mike Neal and Fred Pompermayer. Video by Bruno Lemos.)
(Surfer prize $15,000 – Photo/video prize $4,000)
Andrew Cotton (Croyde,Devon, United Kingdom) at Mullaghmore Head, Ireland on March 8, 2012.
(Photos by Andrew Kilfeather, Conn Osbourne and David Olsthoorn. Video by Jamie Russell.)
Garrett McNamara (Haleiwa, Hawaii, USA) at Priaia do Norte, Nazaré, Portugal on November 1, 2011.
(Photo by Wilson Ribeiro. Video by Jorge Leal.)
Axi Muniain (Zarautz, Basque Country) at Agiti, Spain on December 15, 2011.
(Photo by Eric Chauche. Video by Walter Lang.)
Ollie O'Flaherty (Lahinch, County Clare, Ireland) at Mullaghmore Head, Ireland on March 8, 2012.
(Photos by Christian McLeod and Matt Strathern. Video by Mark Waters.)
Damien "Taco" Warr (Yallingup, Western Australia) at Cow Bombie, Western Australia on October 16, 2011.
(Photo by Jamie Scott. Video by Rick Jakovich.)
(Surfer prize $5,000 – Still photography prize $2,000)
Kohl Christensen (Haleiwa, Hawaii, USA) at Cloudbreak, Fiji on July 12, 2011.
(Photos by Brian Bielmann and Bruno Lemos.)
Nathan Fletcher (San Juan Capistrano, California, USA) at Teahupoo, Tahiti on August 27, 2011.
(Photos by Brian Bielmann, Pete Frieden, Bruno Lemos, Tim McKenna and Benjamin Thouard.)
Tyler Hollmer-Cross (Hobart, Tasmania, Australia) at Shipstern Bluff, Tasmania on May 17, 2011.
(Photo by Andrew Chisholm.)
Bruce Irons (Hanalei,Hawaii, USA) at Teahupoo, Tahiti on August 27, 2011.
(Photos by Brian Bielmann, Tim McKenna, Fred Pompermayer, Pat Stacy and Benjamin Thouard.)
Everaldo "Pato" Teixeira (Florianopolis, Brazil) at Teahupoo, Tahiti on August 27, 2011.
(Photos by Tim McKenna, Fred Pompermayer and Benjamin Thouard.)
The Billabong XXL Global Big Wave Awards are fueled by MonsterEnergy. Verizon Wireless is the official communications provider and Surfline.com is the exclusive surf forecast of the XXL. Sony is the official electronics supporter and Contour the exclusive provider of point of view cameras. The event is sponsored by Surfing Magazine and Air Tahiti Nui airlines.


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Josh Kelley Relocates Family to Utah to Work on New Music
For Josh Kelley, the state of Utah has always been a special place to visit. It's where he and wife Katherine Heigl got married four years ago, and a place they enjoy taking their daughters as often as possible. Now, the famed couple have relocated to Utah for the entire summer to enjoy the beauty and inspiration, all of which the singer hopes will translate on his forthcoming new album.
"I rented a U-Haul and took my whole H-D rig studio all the way up here," Kelley told Taste of Country over the phone, as he and his wife sat by a lake fishing with their newborn daughter "Addie" close by.
"I drove it from California to here. I'm just going to make music all summer," the singer spills. "I've already written about 72 songs right now in the can, and I'm just going to keep writing all summer. I have a bunch of different writers from Nashville who are actually going to be flying out here to do some writing and some fly fishing and some horseback riding and chillin' and some drinkin' — in no particular order [laughs]!"
"We fell in love with it Utah over the years," Kelley admits. "I've been coming out here since I was a kid, and Katie did a movie out here when she was younger. Once you spend a summer here, you realize it's probably the best kept secret on the planet. If it's a secret, it's not anymore [laughs]. It's just beautiful. It never gets humid. It's not a humid place. It gets hot though, so you can have some really great summers."
With the summer touring months quickly approaching, Kelley says he will slip away from his little paradise to do some performances here and there at fairs and festivals, but his main focus during this time will be on family and popping out new music.
"I think that's what's going to take me the furthest, and that's what I want to use to take me to the next level on this next album," notes Kelley. "I want to make something that's going to knock peoples socks off. That's the plan. I feel like I had really good success with 'Georgia Clay,' and I feel like it let everybody know that I'm here and am looking to stay. This album is going to be special. It's time to tear the walls down."


text: Susan Boyle became an overnight sensation after her performance on the television program, "Britain's Got Talent" on April 18, 2009. Her rendition of "I Dreamed a Dream" has been viewed by millions on YouTube. When she first appeared on stage, the crowd began booing and hissing. A few bars into the song, as her earthy, pleasing voice took command and soared over the auditorium, the crowd let out a collective gasp, then cheered raucously. She is a 47-year-old Scottish single woman.


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NOT WINNING! 0 percent tiger's blood!As much as we hate it, Sybil really is dead. That was no soap opera dream sequence fake-out; one of the most beloved characters of Downton is gone, and the Crawleys are in mourning. So am I. And now it looks like we may have something else to mourn: The demise of Robert and Cora's marriage.
The lord of the manor has been turned out of his own bed! Now we know who really runs Downton. Cora is still heartbroken and furious. She doesn't know if she can ever forgive Robert. And frankly, neither can I. Can this marriage be saved?
Well it sure seems as if Lord Sabotage is killing his own chances at forgiveness. Branson wants to baptize the baby a Catholic and he won't have it! Matthew wants to manage the estate better (better, did I say better? No disrespect -- we mean differently, in a less throw-away-money kind of way), and Grantham is insulted! And then, horror of horrors, Isobel allows former prostitute Ethel to serve the ladies of Downton luncheon. Lord Grantham storms the castle to save the ladies from disrepute. Oy, facepalm Grantham. You are so losing it all.
I almost started to feel sorry for him, except he can be such an asshole. (But can we hear it for Ethel, pulling off a successful luncheon like that? Girlfriend! That was a Beyonce at the Super Bowl level performance. I'm so proud of her.) He doesn't mean to be, though.
Does it relieve the misery of Sybil's death a little to be so angry with Grantham? I kind of feel like it does -- both for the Crawleys and for us, the audience. Sadness can be bottomless, without form, but anger always has a direct target.
Anyway, before I get too deep with that ... Don't you love how Branson named the baby after Sybil? That was awfully sweet. And everyone's being so kind and loving toward him. I also liked that scene of Matthew walking with Branson around the estate, talking farming. I hope, somehow, a place can be found for Branson there. I get how he wants to get away from Robert's death stare, but wouldn't you love to see him running a farm? Or even the whole thing?
Speaking of running the farm, another bright spot for this episode was Daisy getting offered her father-in-law's farm. Daisy has such lowly aspirations, is always so grateful for every little morsel, and is such a hard working, loyal person. She's so deserving of that farm! And her father-in-law is right to see the end of estate life in the future. I hope she takes it on.
Anna is loyal, too. But if she really knew what Bates was up to ... Gah, the way he threatened that change in testimony, jabbing that pointy thing into his cellmate's jowl. (What was that, anyway? A dentist's tool?) I used to love Bates, but now he gives me the creeps. Then again, the guy is just doing what he must to survive. Can't blame him -- and he's getting out, apparently. And he's probably going to take his job back and Thomas will be demoted.
Oh poor Thomas, he's flirting with cute James and it's going to end in disaster for him. Dude, you are so screwed! And WHY is he listening to O'Brien's encouragement, anyway? I thought those two were explicitly sworn enemies?
Okay, back to the folks upstairs. So, I think it's kind of shitty of Violet to put Saving the Great Grantham Marriage on Dr. Clarkson. Jeebus, the guy lost a patient to Sir Fancypants and now this? I think it's asking a lot of a doctor who has sworn an oath to LIE about Sybil's chances, but it was kind of him. I guess.
But lest anyone think otherwise: SYBIL'S ECLAMPSIA MOST DEFINITELY WAS TREATABLE, even then. Anyway, well done, Dowager Countess. You and Clarkson saved a marriage.
Next: When are Mary and Matthew having a bay-bay??? Get on it, you two. Enough lovey-dovey pillow talk. Bla bla bla, we'll never take your love for each other for granted, either. BABY. Make one.
Favorite lines:
"People like us are never unhappily married." Dowager Countess
"You're always flabbergasted by the unconventional." Cora to Robert
"Lie is so unmusical a word." Dowager Countess
"Do I LOOK like a frolicker?" Mrs. Padmore
Watch Downton Abbey, Season 3: Episode 5 Preview on PBS. See more from Masterpiece.
Do you think Robert Grantham will ever change with the times, or is he hopelessly stuck in the past?
Image via PBS


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The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy Volunteers
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00001953
Recruitment Status : Completed
First Posted : January 19, 2000
Last Update Posted : March 4, 2008
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
This study aims to learn more about how the immune and hormonal systems function in patients with Sjogren's syndrome, a disease in which the immune system does not function properly. Adult nonpregnant females are invited to participate. Oral contraceptives may not be taken for 6 weeks before and during this study, so another form of birth control must be used, such as abstinence.
There will be two visits. At the first visit, a medical history and physical examination will be conducted, and blood and urine tests will be done. The total amount of blood drawn will be 10 tablespoons. This visit will last 3 hours. At the second visit, participants will have an oral glucose tolerance test. To prepare for it, they must be on a special diet for 3 days beforehand and keep a diary of eating, sleeping, and physical activities for those 3 days. A urine sample will be taken at the beginning of the visit. Subjects must then drink a very sweet carbonated cola. A small plastic tube will be placed into an arm vein. Blood will be drawn through this tube eight times over 3 hours. The total amount of blood drawn will be 17 tablespoons.
Only minor inconveniences are anticipated as a result of participating in this study. Risks from blood tests include soreness, bruising, and minor infection at the puncture site, and dizziness. The oral glucose tolerance test may cause temporary stomach bloating, headache, nausea, and vomiting.
|Condition or disease
|Sjogren's Syndrome
|Study Type :
|Enrollment :
|32 participants
|Official Title:
|Basal and Stimulated Somatostatin Plasma Levels in Patients With Primary Sjogren's Syndrome and in Control Subjects
|Study Start Date :
|November 1999
|Study Completion Date :
|December 2001
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|Child, Adult, Older Adult
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Female gender only, ages 18 to 75.
Patients should have documented primary Sjogren's syndrome as determined by protocol 84-D-0056. The diagnosis of primary Sjogren's syndrome will be based on the presence of all three of the following:
Salivary gland abnormalities;
Lacrimal gland abnormalities;
Serologic abnormalities.
Controls should have no signs or symptoms of Sjogren's syndrome, and negative serologic testing reconfirmed within 2 weeks of the OGTT.
Willingness to: a) participate in phase I and II of the protocol; b) follow the guidelines set to prepare for the OGTT; and c) modify current medical therapy if necessary.
Must be able to comply with protocol procedures.
No patients with "incomplete" Sjogren's syndrome, i.e., with less than three positive findings as described above.
No presence of physical or mental conditions that may interfere with the protocol. These include the following diseases and conditions:
(Present at time of phase I/II): significant disruption of sleep-wake pattern (i.e., less than 4 hours of continuous sleep, on the night before the OGTT only), BMI less than 18 or equal to/greater than 30, anemia with Hgb less than 10 gm/dl, use of tobacco or alcohol;
(Within the past 6 weeks): acute weight change (greater than 5%), use of contraceptives -BCP-, Depoprovera or Norplant), irregular menstrual cycle, lactation, blood drawing in excess of 50 ml, use of recreational drugs, modification of estrogen replacement therapy;
(Within the past 6 months): chronic pattern of weight change (greater than 10%), eating disorders, uncontrolled hypo/hyperthyroidism, breast cancer, lymphoma or other malignancy, pregnancy, treatment for depression, insulinoma, VIPoma, pheochromocytoma, atrophic gastritis, active tuberculosis or treatment for it;
(A history of): HIV+, sarcoidosis, secondary Sjogren's syndrome, bleeding diathesis, organ transplant, severe neuroendocrine, renal, cardiovascular, pulmonary or gastrointestinal disease (e.g., renal insufficiency, unstable angina, heart failure, severe emphysema, Crohn's disease), diabetes mellitus, acromegaly and mental retardation.
No contraindications to OGTT. These include:
Hospital inpatient status, acute illness, immobilization, starvation, severe emotional distress within one week of the OGTT;
Low carbohydrate diet (less than 150 g/day) for 3 days preceding the OGTT;
Therapy which impairs glucose tolerance: e.g., niacin, thiazide diuretics, phenytoin, excess thyroxine or psychotropic drugs within 1 month of phase I, oral contraceptives within 6 weeks of phase I, glucocorticoid treatment within the past 6 months (or one year if treatment lasted over 2 weeks), Beta blockers/agonists (e.g., terbutaline) within 2 days of phase I;
Diabetes mellitus;
Glucose intolerance.
Subjects may not take medications that can affect somatostatin levels, such as antidepressants, benzodiazepines, neuromodulators (e.g., cholinergic, alpha/beta adrenergic), oral contraceptives (BCP), steroid hormones (with the exception of estrogen replacement therapy -ERT-, for which subjects will be matched), immunomodulators, anticonvulsants (e.g., carbamazepine), cimetidine -Tagamet® (Registered Trademark)-, herbal remedies (because of their variable substance content). Subjects may not take drugs affecting gastrin secretion: antacids (e.g., Maalox® (Registered Trademark), Mylanta® (Registered Trademark), H(2) receptor antagonists (e.g., famotidine -Pepcid® (Registered Trademark)-, ranitidine -Zantac® (Registered Trademark)-), cathecolamines, atropine, haloperidol. To become eligible, subjects should be able to safely discontinue these medications at least one month prior to phase I. Antacids, H(2) antagonists and neuromodulators (e.g., Salagen) may be discontinued 2 days prior to phase I.
Patients cannot have take experimental drugs within 1 month of the beginning of the protocol.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001953
|United States, Maryland
|National Institute of Dental And Craniofacial Research (NIDCR)
|Bethesda, Maryland, United States, 20892
|ClinicalTrials.gov Identifier:
|NCT00001953 History of Changes
|Other Study ID Numbers:
|First Posted:
|January 19, 2000 Key Record Dates
|Last Update Posted:
|March 4, 2008
|Last Verified:
|December 2001
Keywords provided by National Institutes of Health Clinical Center (CC):
Endocrine System
Salivary Glands
Glucose Tolerance Test
Growth Hormone
Sjogren's Syndrome
Additional relevant MeSH terms:
Sjogren's Syndrome
Dry Eye Syndromes
Pathologic Processes
Arthritis, Rheumatoid
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Salivary Gland Diseases
Mouth Diseases
Stomatognathic Diseases
Lacrimal Apparatus Diseases
Eye Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs


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Two Jacksonville residents took center stage this week as contestants on two of the most popular shows on TV. Carlos Garland, 25, a graduate of Douglas Anderson School of the Arts and a student at Jacksonville University, performed on "So You Think You Can Dance," while 19-year-old graduate of The Bolles School/University of Florida student David Ferman juggled and did a balancing act on "America's Got Talent."
The good news is one of them advanced to the next round. The bad news is the other one didn't.
Spoiler alert: Don't click on the links if you don't want to know if:
Garland made it to SYTYCD's top 18 ...


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First Aid Courses for Scuba Divers
Whether it is being on the scene of an accident or witnessing a health-related emergency, most people will be involved in a crisis situation at some point in their lives. Are you prepared to help? Do you have the skills to respond quickly?
Developed by medical experts, DAN's courses are easy to understand and designed to provide you with the skills and confidence you need to respond in emergency situations. DAN first aid courses prepare divers to manage injuries related to scuba diving. All courses meet the ILCOR and AHA 2015 guidelines. The training can also extend to other environments. Isn't it worth a few hours one evening or weekend to learn the skills that could save a life?
Developed by Dive Medicine Physicians and Scuba Diving Educators
Emergency Oxygen
Emergency Oxygen
Assist with Scuba Diving Injuries & Non-Fatal Drowning
- Primary diving first aid
- Learn oxygen delivery options
- Provide oxygen to breathing or non-breathing injured divers
4-5 hoursLearn More...
First Aid for Hazardous Marine Life Injuries
First Aid for Hazardous Marine Life Injuries
Assist with Stings, Bites, Seafood Poisoning
- Identify hazardous marine life
- Practice treating injuries
- Gain tools to avoid injuries
5 HoursLearn More...
Neurological Assessment
Neurological Assessment
Recognize signs of Stroke & Decompression Illness
- Recognize nervous system injury
- Learn assessment techniques
- Uncover subtle changes
- F-A-S-T Assessment
4 HoursLearn More...
Basic Life Support:
CPR and First Aid
Basic Life Support:
CPR and First Aid
Learn emergency skills Help save a life
- Meets ILCOR/AHA 2015 Guidelines
- Manage shock and choking
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Diving Emergency Management Provider
Diving Emergency Management Provider
Comprehensive Diving First Aid Course
- Develop CPR skills
- Provide oxygen first aid
- Conduct neurological assessment
- Treat injuries from marine life
16 HoursLearn More...
Being prepared can often save a life.
Empower yourself with the tools you need.
Take a course now!Find an Instructor
Professional Divers & Health Care Providers
Diving First Aid for Professional Divers
Diving First Aid for Professional Divers
Emergency Oxygen, Neurological Assessment Marine Injuries, CPR
- Ideal for Commercial Divers
- Meets OSHA Guidelines
- Covers bloodborne pathogens
- Advanced oxygen and CPR
16 HoursLearn More...
CPR Health Care Provider with First Aid
CPR Health Care Provider with First Aid
Learn advanced life support & first Aid skills
- 1 and 2 person CPR
- Child and infant CPR
- Obstructed-airway techniques
- Suctioning techniques
8 HoursLearn More...
Is diving a part of your job or volunteer duties?
The Diving First Aid for Professional Divers (DFA Pro) course is aimed at commercial, professional, scientific divers and aquarium staff and volunteers and meets the 2015 Guidelines for Resuscitation & OSHA.
The course is comprised of information from the Emergency Oxygen for Scuba Diving Injuries, Neurological Assessment, First Aid for Hazardous Marine Life Injuries and CPR HCP plus Bloodborne pathogens.
Are you ready for a higher level of first-aid training?
The CPR Health-Care Provider with First Aid course teaches 2-person techniques of basic life support for adults, children and infants. It includes First-Aid and BLS skills applicable to the diving market, resuscitation techniques for the nondiving health-care market and skills to meet the ILCOR and AHA 2015 guidelines.Find an Instructor


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Charles Degotte was a Belgian comics and lay-out artist who had a long career at Spirou magazine. He's best known as the creator of the 'Flagada' bird (1961-1993), around whom he created cartoons and comics. Another long-running series of his hand was the gag comic 'Les Motards' (1984-1993). Degotte was furthermore active as a children's book writer, illustrator and TV animator. Sadly his career ended early when he committed suicide.
Born in 1933 in Verviers, he eventually settled in Brussels. After having worked in the decoration atelier of a department store for several years, he found employment with the art studio of the publishing house Dupuis. He made several editorial illustrations for the magazine Spirou, and was engaged with the magazine's lay-out. He also wrote several children's books in the Collection du Carrousel between 1966 and 1968 (including one in cooperation with his wife Luce), and also participated in several projects of the animation department TVA Dupuis. He worked on the first adaptations of Peyo's 'Smurfs' for TV, and developed the characters 'Les Zippies' for Belgian television.
Starting in 1961, he also produced a great many short stories and mini-books for Spirou, which starred a wacky bird with a propeller at his tail, called the 'Flagada'. It became Degotte's most enduring character, and although Dupuis never published the comic in book format, the bird remained a regular feature in Spirou throughout the 1960s, 1970s and 1980s. An emblematic character, the 'Flagada' was often featured in Franquin's 'Gaston' gags, appearing on posters, as a piece of merchandise, and a even as a costume.
The 'Flagada' started out in the mini-books section in 1961, but also appeared in the magazine's regular pages from 1966, including several short stories, a series of gags under the title 'Le flagada et les pépins de la pêche' (1968-1974) and two serials, 'Emilius le terrible' (1979) and 'Le martin bêcheur' (1982). In the late 1970s, Degotte was regularly aided by Bom for the scriptwriting. It wasn't until 1981 that Éditions Pepperland issued the first book collection in 1981, followed by books published by M.C. Productions, Dargaud and Le Coffre à BD.
In 1984, he created 'Les Motards', an absurd gag series about a group of anthropomorphic bikers, that he wrote and drew until his death. Dupuis collected the gags in ten books between 1986 and 1993. Having suffered from a long depression, Charles Degotte took his own life on 20 April 1993.


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Archive for The Walking Dead Season 6 Episode 2 Online Video
The Walking Dead Season 6 Episode 6.02 New Promotional PhotosPosted by: | Comments
Watch new unreleased promotional photos from the second episode of sixth season of TWD
Watch The Walking Dead Season 6 Episode 6.02 in HD Quality Here for Free
Watch The Walking Dead Season 6 Episode 2 Online (S6 x E2) _ Titled "Jss"Posted by: | Comments
Watch The Walking Dead Season 6 Episode 2 Online (S6 x E2) _ Titled "Jss" aired October 18, 2015.
The Walking Dead Season 6 Episode 2
Episode Name: Jess
Air date: 10/15/2015
Summary: When it appears that things are starting to normalize in the settlement, a new problem arises for the Alexandrians.
Watch The Walking Dead Episode 6×01 Promo
Click the Button Below to Watch Full Episode Online Free:-
TWD Spoilers :- Season 6 Morgan and Carol's Relationship explored in the Episode 2Posted by: | Comments
Though it's unclear why the murderous group of survivors exactly sounded the horn, one thing is for sure: they are attacking Alexandria in episode 2 while most of the male residents of the walled community are still away.
"The Walking Dead" fan site revealed that a lot of Alexandrians will die from the attack. Carol will reportedly be ditching her Stepford-esque housewife disguise in the episode, and will effortlessly switch to her badass zombie killer persona.
According to Spoiler TV's advance preview of the episode, the former battered wife will have more importance in this upcoming episode than in the premiere. While Deanna appears to be safe with Maggie on her side, the former's son, Spencer, might be in big trouble, as TSDF revealed that he will be attacked by the Wolves while he's in the watch tower.
According to Spoiler TV, Morgan and Carol's relationship will be explored in the episode, and the scene between them will be one of the highlights of the episode. Which among these are you most excited to see in episode 2? Let us know what you think in the comments section below!
"The Walking Dead's" "JSS" airs on Sunday, Oct. 18, at 9 p.m. on AMC.\
Click the Button Below to Watch Full Episode Online Free:-


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Story highlights
- FIFA to trial goal-line technology during England's friendly with Belgium at Wembley
- Hawk-Eye technology won't be available for match officials during the Euro 2012 warm up
- If the tests prove successful goal-line technology could be ratified in early July
- English Premier League chairman has suggested it could be introduced mid-season
It was the scene for one of the most famous controversies in soccer history. Did England striker Geoff Hurst's shot during the 1966 World Cup final at Wembley cross the line?
The Russian who was running the line that day thought so and his decision helped England to a 4-2 win over West Germany -- their only major tournament success to date.
Forty-six years later, the same London stadium will provide the setting for a major test of pioneering goal-line technology (GLT), that could revolutionize the game of football forever.
British firm "Hawk-eye" employ a series of cameras mounted inside the goal frame and their approach will be tested during England's Euro 2012 warm-up match with Belgium, though none of the information will be available to the match officials.
Scientists and FIFA officials will analyze the results and if they prove successful, the technology could be ratified at a meeting of the International Football Association Board (IFAB) in early July.
The experiment in front of an estimated crowd of 90,000 at Wembley follows the first Hawk-eye trial at a non-league English cup match earlier this month. An alternative system, designed by German company "GoalRef" is also in the final stages of testing.
It is somewhat ironic the technology is to be examined during an England match as the team were on the wrong end of a refereeing decision at the 2010 World Cup.
Frank Lampard's shot was disallowed during a second round match with Germany despite replays showing the ball was a full yard over the goal-line.
That incident in South Africa prompted FIFA to overturn their long-held stance on goal-line technology and begin trials.
A statement on FIFA's website said: "Only the EMPA observers, IFAB and FIFA representatives at Wembley will have access to the GLT system readings.
"Therefore, should a goal-line incident occur at this or any of the 'test' matches, the system will not be utilized by the match officials. It means the GLT system will have no influence on the outcome of the matches in which the system is being tested.
"Such tests, along with those being conducted for the GoalRef system in Denmark, could lead to the International Football Association Board approving the introduction of GLT at its special meeting at the beginning of July."
There have been several contentious incidents in the last English season that has renewed calls for the technology to be introduced.
Chelsea were awarded a goal in an FA Cup semifinal against Tottenham at Wembley that was shown not to have crossed the line, while Queens Park Rangers defender Clint Hill's header against Bolton wasn't given despite being well over the line.
English Premier League chairman Richard Scudamore has said he is keen to introduce the technology next season if it is rubber-stamped by FIFA.
FIFA have also confirmed that referees are to be drug tested to check they are not taking performance enhancing substances.
At a meeting of the world governing body's executive committee, chief medical officer Jiri Dvorak said match officials should be subject to the same tests as players.
"We have to consider referees as part of the game," he was quoted as saying by the UK Press Association.
"We have started to discuss this and this is something for the future which will be discussed to include possibly an anti-doping program for referees.
"We do not have an indication that this is a problem but this is something we have to look at. The referees are a neglected population."


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COLORADO SPRINGS, Colo.—Just weeks after the former Colorado Springs City Council voted to expand the Colorado Springs Community Solar Garden, the new council is set to reverse course.
New council president Keith King said the backtracking will not scrap renewable energy programs. The council needs more information about other cost-efficient ways to structure the program, he said.
The gardens allow customers of Colorado Springs Utilities to buy or lease solar panels installed on a farm and get credit on their utility bills.
According to the Colorado Springs Gazette ( http://tinyurl.com/cwxh8xa), residential customers could be asked to pay an average of $3 to $4 more a year for the solar garden program.
David Amster-Olszewski, president of the community solar garden company SunShare, said there has already been an eight-month public process. All issues and costs were examined before the City Council voted April 9 to approve electric rate increases to expand a pilot project that created the area's first community solar gardens at the Venetucci Farm in 2011, he said.
"Businesses have a lot of opportunity and there are lot of places businesses can go to be successful. Before they withdraw this, they need to say let's learn and then decide. Don't kill it first and then ask questions. That is not a friendly way of doing business," Amster-Olszewski said.
The pilot program already has provided up to 2 megawatts of solar-generated power. The expansion would add 10 more megawatts by 2016, paid for by ratepayers. The cost of expansion could cost up to $33 million over 20 years.
Amster-Olszewski said if the council votes to rescind the changes it made to the electric rates, it would send an anti-business message to all renewable energy companies.
At least 14 states have passed legislation that allows the building of solar gardens.
Added to the resolution on Monday was a call for a public discussion and information gathering meeting with interested community members within 60 days.
Earlier this month local business leaders said that there would be no way to recover the cost increases, especially for large industrial customers, and economic development could suffer.
Information from: The Gazette, http://www.gazette.com


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rose plastic's MH-Pack receives the German Packaging Award 2015
rose plastic received the German Packaging Award 2015 for its new "MH-Pack" in the category sales packaging. Only two years ago, the company was awarded the German Packaging Award for its product innovation.
The Chief Executive Officer Thiemo Rösler was very pleased that the new product "MH-Pack" has convinced the committee this year. Just like his father Peter Rösler, who led rose plastic until the end of 2013, the development of new products is important to him. "We are committed to developing and implementing creative and innovative packaging solutions for our customers and markets," says Thiemo Rösler. The award confirms that we are on the right track.
With its new MH-Pack, rose plastic has developed a high quality, stable individual packaging for manufacturers and end users of milling heads. The MH-Pack is intuitive and easy to open and close. The packaging will only then be removed, when the milling heads are safely inserted into the shank holder. Thanks to the extremely easy handling the user cannot come into contact with the sharp-edged milling heads, thus ensuring the prevention of physical injuries. The MH-Pack doesn't need any additional material, such as protective caps or foam, also the packaging is reusable.
The German Packaging Award is granted each year for innovative and creative packaging ideas by the German Packaging Institute (DVI). Out of nearly 200 entries in six different categories, 27 concepts won the prestigious prize this year.


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The crowded ranks of the free-agent kicker class have thinned at the top.
According to CBS' Jason La Canfora, the Titans and PK Rob Bironas reached agreement on a two-year contract Thursday.
Bironas, 35, was PFT's top-ranked kicker in the Class of 2013 (No. 86 0verall). He is the first member of the PFT Free Agent Hot 100 to strike a deal. Bironas connected on 25-of-31 field goals a season ago.
With Bironas apparently off the market, the Seahawks' Steven Hauschka and the Browns' Phil Dawson rank among the top options in a deep free-agent PK group.


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News & Events
For the Media
Clarkson University Researcher to Speak at June 5 Autism Conference
Clarkson Researcher to Speak at June 5 Autism Conference
A photograph for media use is available at http://clarkson.edu/news/photos/awoods.jpg
Clarkson University Research Assistant Professor Alisa G. Woods of the Department of Chemistry and Biomolecular Science will present at the ICare4Autism International Autism Conference on June 5.
The annual cross-disciplinary conference focuses on autism treatment and educational initiatives, cutting-edge research from leading institutions, groundwork for effective educational approaches in schools and the most recent findings from the world's top practitioners. Woods is one of 12 researchers and medical doctors presenting at the conference; she will discuss "Protein Biomarkers in Autism Spectrum Disorder."
Approximately one in 50 school-age children are diagnosed with autism, according to a recent study from the Centers for Disease Control and Prevention. Roughly 1 million children ages 6 to 17 face formidable challenges in communication, behavior, and social interaction.
On June 5, ICare4Autism, the International Center for Autism Research & Education, is gathering leading clinicians and researchers at Yeshiva University's Albert Einstein College of Medicine in Bronx, N.Y. The conference aims to catalyze groundbreaking treatment approaches.
Woods works within Clarkson's Laboratory for Biochemistry and Proteomics and the SUNY Plattsburgh Neuropsychology Clinic and Psychoeducation Services. She focuses on the field of psychobiochemistry, specifically searching for biological indicators for neurodevelopmental disorders and mental illness. Her current research projects include the study of biomarkers for autism spectrum disorder and the long-term consequences of attention deficit hyperactivity disorder.
She received her bachelor of science degree in psychology from SUNY Plattsburgh, Ph.D. in psychobiology from the University of California Irvine, post-doctoral training in neuroanatomy at the University of Freiburg, Germany, and completed a master's degree in mental health counseling at the University of Massachusetts, Boston. Her research has been supported by the Redcay Foundation, National Science Foundation, National Institute of Mental Health and the Alexander von Humboldt Foundation.
To register for the event, visit http://www.eventbrite.com/event/5803148373 .
Clarkson University launches leaders into the global economy. One in five alumni already leads as a CEO, VP or equivalent senior executive of a company. Located just outside the Adirondack Park in Potsdam, N.Y., Clarkson is a nationally recognized research university for undergraduates with select graduate programs in signature areas of academic excellence directed toward the world's pressing issues. Through 50 rigorous programs of study in engineering, business, arts, sciences and health sciences, the entire learning-living community spans boundaries across disciplines, nations and cultures to build powers of observation, challenge the status quo, and connect discovery and engineering innovation with enterprise.
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