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Bactrim Side Effects
Generic Name: sulfamethoxazole / trimethoprim
Note: This document contains side effect information about sulfamethoxazole / trimethoprim. Some of the dosage forms listed on this page may not apply to the brand name Bactrim.
For the Consumer
Applies to sulfamethoxazole / trimethoprim: oral suspension, oral tablet
Other dosage forms:
Along with its needed effects, sulfamethoxazole/trimethoprim may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking sulfamethoxazole / trimethoprim:
- Abdominal or stomach pain
- black, tarry stools
- blistering, peeling, or loosening of the skin
- changes in skin color
- chest pain
- chills
- cough or hoarseness
- dark urine
- diarrhea
- dizziness
- fever with or without chills
- general feeling of tiredness or weakness
- headache
- itching
- joint or muscle pain
- light-colored stools
- loss of appetite
- lower back or side pain
- nausea
- pain, tenderness, or swelling of the foot or leg
- painful or difficult urination
- pale skin
- rash
- red skin lesions, often with a purple center
- red, irritated eyes
- shortness of breath
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- swollen or painful glands
- tightness in the chest
- unpleasant breath odor
- unusual bleeding or bruising
- vomiting of blood
- wheezing
- yellow eyes or skin
Incidence Not Known
- Abdominal or stomach tenderness
- back, leg, or stomach pains
- bleeding gums
- blindness or vision changes
- blisters, hives, or itching
- bloating
- blood in the urine or stools
- bluish-colored lips, fingernails, or palms
- burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings
- burning of the face or mouth
- chest pain
- cloudy urine
- confusion
- constipation
- continuing ringing or buzzing or other unexplained noise in the ears
- convulsions
- cracks in the skin
- decreased frequency or amount of urine
- diarrhea, watery and severe, which may also be bloody
- difficulty with breathing
- difficulty with swallowing
- fainting spells
- general body swelling
- general feeling of discomfort or illness
- hair loss
- hearing loss
- hives
- increased thirst
- indigestion
- irregular heartbeat
- large, flat, blue, or purplish patches in the skin
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- loss of heat from the body
- muscle or joint pain
- nosebleeds
- not able to pass urine
- numbness or tingling in the hands, feet, or lips
- pain or burning while urinating
- pinpoint red spots on the skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- raised red swellings on the skin, the buttocks, legs, or ankles
- redness of the white part of the eyes
- redness, swelling, or soreness of the tongue
- sores, ulcers, or white spots on the lips or in the mouth
- soreness of the muscles
- stiff neck or back
- swelling of the face, hands, legs, and feet
- unsteadiness, trembling, or other problems with muscle control or coordination
- unusual weight loss
- weakness in the hands or feet
- weakness or heaviness of the legs
- weight gain
Some side effects of sulfamethoxazole / trimethoprim may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More Common
- Passing of gas
Incidence Not Known
- Discouragement
- feeling of constant movement of self or surroundings
- feeling sad or empty
- increased sensitivity of the skin to sunlight
- irritability
- lack of feeling or emotion
- loss of interest or pleasure
- nervousness
- redness or other discoloration of the skin
- seeing, hearing, or feeling things that are not there
- sensation of spinning
- severe sunburn
- trouble concentrating
- trouble sleeping
- uncaring
- weight loss
For Healthcare Professionals
Applies to sulfamethoxazole / trimethoprim: intravenous solution, oral suspension, oral tablet
Rare (0.01% to 0.1%): Thrombophlebitis
Very rare (less than 0.01%): Polyarteritis nodosa, syncope
Postmarketing reports: QT prolongation resulting in ventricular tachycardia and torsade de pointes[Ref]
Common (1% to 10%): Skin rash, urticaria
Very rare (less than 0.01%): Photosensitivity, exfoliative dermatitis, fixed drug eruption, erythema multiforme, erythema nodosum, Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis, bullous dermatitis, purpura, angioedema
Frequency not reported: Pruritus[Ref]
Common (1% to 10%): Diarrhea, nausea, vomiting, anorexia
Very rare (less than 0.01%): Constipation, glossitis, stomatitis, pseudomembranous colitis, pancreatitis, abdominal pain
Frequency not reported: Sore mouth, moniliasis[Ref]
Very rare (less than 0.01%): Leucopenia, neutropenia, thrombocytopenia, pancytopenia, bone marrow depression, agranulocytosis, aplastic anemia, hemolytic anemia, eosinophilia, purpura, hemolysis
Frequency not reported: Megaloblastic anemia, methemoglobinemia, hypoprothrombinemia, granulocytopenia[Ref]
Rare (0.01% to 0.1%): Jaundice
Very rare (less than 0.01%): Hepatitis (including cholestatic jaundice and hepatic necrosis), disturbance in liver enzymes, elevated serum transaminases, elevated bilirubin[Ref]
Very rare (less than 0.01%): Hypersensitivity, anaphylaxis, anaphylactoid reaction drug fever, chills, allergic vasculitis resembling Henoch-Schonlein purpura
Frequency not reported: Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), anaphylaxis, allergic myocarditis, erythema multiforme, exfoliative dermatitis, angioedema, serum sickness-like syndrome, generalized allergic reactions, generalized skin eruptions, conjunctival and scleral injection, photosensitivity, pruritus, urticaria, rash, periarteritis nodosa, systemic lupus erythematosus (SLE)[Ref]
Common (1% to 10%): Monilial overgrowth[Ref]
Rare (less than 0.1%): Local reaction, pain, slight irritation[Ref]
Very common (10% or more): Hyperkalemia (particularly in the elderly and in HIV patients)
Very rare (less than 0.01%): Hypoglycemia, hyponatremia, metabolic acidosis[Ref]
Rare (less than 0.1%): Rhabdomyolysis (mainly in AIDS patients)
Frequency not reported: Arthralgia, myalgia[Ref]
Nervous system
Very common (10% or more): Headache
Very rare (less than 0.01%): Aseptic meningitis (rapidly reversible on withdrawal of therapy but can reoccur on rechallenge), convulsions, peripheral neuritis, ataxia, vertigo, dizziness, tremor, lethargy, paresthesia, convulsions, peripheral neuritis, tinnitus[Ref]
Very rare (less than 0.01%): Uveitis[Ref]
Very rare (less than 0.01%): Depression, hallucination, confusional state, agitation, anxiety, abnormal behavior, insomnia, nightmares[Ref]
Very rare (less than 0.01%): Renal tubular acidosis, Impaired renal function (sometimes reported as renal failure), hematuria
Frequency not reported: Serum creatinine increased, blood urea nitrogen increased
Postmarketing reports:
Frequency not reported: Renal failure, interstitial nephritis, elevated BUN and serum creatinine, toxic nephrosis with oliguria and anuria, tubular necrosis, crystalluria, aggravation of renal disease, azotemia, hyperkalemic renal tubular acidosis, overestimations of normal creatinine values[Ref]
Very rare (less than 0.01%): Cough, dyspnea, lung infiltration, shortness of breath, wheezing, epistaxis[Ref]
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Sulfamethoxazole-Trimethoprim (sulfamethoxazole-trimethoprim)." SICOR Pharmaceuticals Inc, Irvine, CA.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
Related questions
- What dose of co-trimoxazole is used in a patient with a UTI?
- Can I drink alcohol while taking sulfamethoxazole / trimethoprim DS tablets?
- Can you take Bactrim DS if you're allergic to penicillin?
- How long does it take for a boil to heal while taking Bactrim?
More about Bactrim (sulfamethoxazole / trimethoprim)
- During Pregnancy
- Dosage Information
- Patient Tips
- Drug Images
- Drug Interactions
- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- 361 Reviews
- Generic Availability
- Drug class: sulfonamides
Consumer resources
Other brands: Septra, Septra DS, Sulfatrim Pediatric, Cotrim, Sulfatrim


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After some great feedback following the launch of our Windows 8 in education eBook, we are thrilled to announce the launch of our Windows 8 in education UK microsite.
The microsite is designed to help surface, excuse the pun, some key Windows 8 in education assets that look closely at our new OS specifically through an edu lens.
In addition to the eBook, a key new asset that has literally just been added to the microsite is our Windows 8 in education video. The video showcases how both UCL and Hartsbrook E-Act Free School are using Windows 8 to build 21st skills and create more emotional connections with learning.
I was involved in the filming of this video and both institutions are doing some amazing work with Windows 8, and technology in general. I personally loved the impact that Windows 8 had on the primary age students at Hartsbrook, though. Seeing the look on the young students faces when a picture they had just taken on their Windows Phone seamlessly synced to SkyDrive on their Windows 8 classroom PC's was awesome! Charlotte Beckhurst, and the rest of the team at Hartsbrook, are doing some fantastic work and I can't wait to see her share her experiences on our stand at Bett next week.
If you are coming to Bett and want to check out Charlotte's session, our full Learn Live Theatre schedule is available via our Bett 2013 microsite. We hope to see you there!
Windows 8 apps also sit front and centre of our new Windows 8 in education microsite. With a rapidly growing selection of education apps from the likes of Pearson, RM and Autology, the education category in the Windows Store has definitely been one of the most dynamic and innovative areas since launch.
Our app showcases offer a detailed overview of specific apps combined with screencasts, screenshots and information to allow you to learn more about how the app can help directly within your institution.
The intention is not to list every education app in the store, but offer a curated overview of a selection of UK apps available both today and over the coming months.
We will be adding fresh content, especially around new apps, to the site on a regular basis so be sure to come back regularly and keep up to date with what is going on. We hope you find the site useful and informative look forward to sharing additional updates over the coming weeks/months.
If you have a favourite education app, we would love to hear more in the comments below. Also, if you are attending Bett 2013, make sure you pop over and say hi. We are on stands D270 and E270.

subset: commoncrawl


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The academic work of Heinz von Foerster was, and remains, highly influential in a number of disciplines, namely due to the pervasive implications of his distinction between first and second order cybernetics (and its antecedent ideas). Where first order cybernetics may be simply described as the study of feedback systems by observation, second-order cybernetics extends this observation of a system to incorporate the observer itself: it is reflexive in that the observation of the feedback system is itself a feedback system to be explained. While I am familiar with this concept, I am not particularly familiar with the body of work produced by von Foerster to instantiate this concept, although I have encountered numerous references to him, particularly when the subject is related to enactivism.
In 2003, Bernard Scott republished a summary of von Foersters' work which he originally published in 1979. The original paper was published just a few years after the official retirement of von Foerster, who apparently (as many an academic has before and since) continued his work for many subsequent years. It serves as a summary of the breadth of work and its contribution, and was republished partly in recognition of the continuing, and expanding, influence it exerts. This post is a very brief summary of this summary paper.
In general terms, von Foerster views on computation and cognition seem to be inherently integrated, holistic, proposing dynamic interactions between the micro, the macro and the global. This view thus contrasts with functional models of cognitive processes which in their nature, can only be static snapshots of the dynamic interactions at play: cf autopoietic theory that extends this notion with the principles of self-reconstitution and organisational closure. Particularly, he emphasises the necessity of considering perception, cognition and memory as indivisible aspects of a complete integrated cognitive system, cf enactivism.
With this consideration as a consistent thread, four primary phases in the development of von Foersters' research are identified. Firstly is his consideration of large molecules as the basis for biological computation, rather than the prevailing focus on neural networks, and that 'forms' of computation underlie all computational systems. Secondly is the exploration of self-organisation, and the reconciliation of organisation with the potential paradox of self-reference. In this sense, a system that increases in order (organisation) requires that its observer adapts its frame-of-reference to incorporate this: if this were not required of the observer, then the system can not be regarded as self-organising. The resulting infinite recursion provides an account of the conditions necessary for social communication and interaction: a consequence of the second order cybernetics. Thirdly is a focus on the nature of memory as being key to understanding cognition and consciousness. Returning to the notion of holistic cognition described above, this is in contrast to the perspective of memory as a static storage mechanism which was prevalent among behaviourist psychologists, and still remains prevalent in the work of designers of synthetic cognitive models and architectures (the countering of which is a key theme of my own research). The fourth and final identified phase (of the original 1979 paper that is) is the formalisation of the concept of self-referential systems and analysis as recursive computation, and the extension of this to apply also to the observer.
The threads of self reference and a holistic perspective have, as noted above, had a wide influence, and continue to do so. I did not realise before that Maturana and Varela's well known formulation of autopoiesis was done at the lab that von Foerster led (the Biological Computing Laboratory, University of Illinois). The relationship is of course clear now that I know about it (!): autopoiesis builds upon the self-reference and holism with self-reconstitution and organisational closure to form a fully reflexive theory. Similarly, enactivism seems to owe much to von Foersters' influence, with its integrated consideration of agent and environment, embodiment and cognition - a theme that has become increasing prevalent in recent years among those working on cognitive robotics with a more theoretical perspective - extending to the consideration of social behaviour. In all, the principle of second-order cybernetics and the theoretical perspectives upon which it is based remain important in the consideration of cognition and human behaviour despite its seemingly abstract theoretical nature, and Heinz von Foerster played a rather prominent role in providing its underpinnings.
Some of the 'buzzwords' raised in the summary of von Foersters' research which carry through as such today (among others - and I use the term buzzwords without any pejorative intent, merely as a 'note-to-self'):
- second order cybernetics
- self-organisation
- the holistic nature of cognition (developed as enactivism)
Paper reference:
Scott, B. (2003), "Heinz von Foerster - an appreciation (revisited)", Cybernetics and Human Knowing, 10(3/4), pp137-149


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News Anchor Can't Stop Laughing During Story of Swimming Cat [VIDEO]
This is funny! A news anchor in Roanoke, Virginia was reporting a story about a cat that is swimming to lose weight.
She holds it together for about 10 seconds then can't stop laughing. I must admit the poor wet cat in a life vest is priceless!


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Third High School Proposed for Tyler
The Tyler Independent School District is proposing a new high school for the city depending on the outcome of a May bond issue.
TISD officials said the A.T Stewart Academy of Excellence would replace Stewart Middle School and students would have to apply to attend the new high school.
The proposed third high school would offer non-traditional classes including college ready programs, and advanced technology classes.
Voters will decide May 11 on the proposed $160.5 million dollar bond package that calls for a brand new middle school, in addition to new schools for Boulter and Moore middle schools. The proposed measure also would include renovations to Dixie and Rice elementary Schools.


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The Ecru color is old-fashioned and classic looking. The skirt fit my 60 year old bassinet just right and made somethi... Read more
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Here you will find a list of the largest agencies we are connected to :
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Residency at The Center Art Exhibitions presents Abstracted Time, an art show featuring the amazing works of visual artists Anne Webb and Geraldine Brettmann. As described by the artists:
Time can described as an abstract because of its subjective nature. It can be interpreted in different ways by different emotions at different points of our lives.
Our lives are filled with abstracted memories. In our quest to live in the present we tend to put our past behind, we have our abstracted memories to keep us moving forward, how we experienced life in the past and how we interpret those memories. We use the abstract memories from the past to interpret our present state of being. The abstracted time of the present of which the here and now is always among us, always ever present. The abstracted time of the future is always something we look at in front to use constantly to create our world. The abstracted time of past and present help to create our future. Our abstract creations are by our own mind and flow through us and into our creations.
The exhibition will be on display June 18 to July 9. Viewing hours this summer will be 8:00am to 4:30pm Monday through Thursday. There will be a free artists reception on Saturday, June 23 from 6:00pm to 8:00pm.
Mansfield ISD605 East Broad StreetMansfield, Texas 76063Phone: 817.299.6300 www.mansfieldisd.org
Cora Spencer Elementary3140 South Camino LagosGrand Prairie, TX 75054Phone: 817.299.6680 Fax: 817.453.6580contact the webmaster | map to campus


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Originally Posted by NadiaK
I am selling Charlie Bears Grayson a jointed 14" panda designed by Isabelle Lee. This bear is long sold out and hard to find. He comes with his original bag and certificate. Asking $60 shipped in the US. Smoke free home. Please pm me if interested.
This is his stock photo:
. Does this one come with the necklace??
.Karen Anne
Forum Rules


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A capsule look at the Eastern Conference and Western Conference semifinal matchups in the NBA playoffs:
No. 1 INDIANA PACERS (56-26 regular season, 4-3 in playoffs) vs. No. 5 WASHINGTON WIZARDS (44-38, 4-1)
Season series: Pacers, 2-1. Indiana routed Washington at home twice during its sizzling start before the new year, then lost on the road during its late-season slide. The Wizards shot under 40 percent in all three games and averaged 70.5 points in their losses, when John Wall shot 8 of 29. Wall rebounded with 20 points and eight assists in the Wizards' 91-78 home victory on March 28.
Story line: Forced to seven games in the first round before getting by a 38-win Atlanta team, the Pacers will try again to find the level they played at in the first half of the season. The Wizards had a surprisingly easy five-game victory over Chicago and are in the second round for just the third time since 1979.
Key matchup I: Roy Hibbert vs. Marcin Gortat. After a mostly miserable series against the Hawks' nontraditional centers, maybe Hibbert will be more comfortable and effective in this round against someone who plays more his style. Gortat had a pair of 17-point games against Indiana during the season and averaged 10.8 points and 9.6 rebounds in the first round.
Key matchup II: Paul George vs. Wall. Besides his six double-doubles in the series, George defended Hawks point guard Jeff Teague, and sticking with that strategy means trying to cool off Wall, who averaged 18.8 points in his first postseason series. George struggled a bit against the Wizards, shooting 2 for 14 and 6 for 22 in the final two games.
X-factor: Trevor Ariza. The Pacers gave up a number of open 3-point looks to the Hawks and will have to keep a better eye on the Wizards' swingman, who was 13 of 28 behind the arc against Chicago.
Prediction: Pacers in 6.
No. 2 MIAMI HEAT (54-28, 4-0) vs. No. 6 BROOKLYN NETS (44-38, 4-3)
Season series: Nets, 4-0. And that doesn't even count a 2-0 mark in the preseason. It's one-sided in terms of wins and losses, and really not in most other categories. Three of Brooklyn's wins in the regular season were by a single point, and the fourth was in double overtime. Dwyane Wade played in only two of four games for Miami, and Brooklyn's Kevin Garnett also missed two meetings in the series.
Story line: Brooklyn has already won four games that count against Miami. Can the Nets do it now when it really counts? The Nets are coming in after going on the road and winning a Game 7 against Toronto, while Miami will have had more than a week off after sweeping away the Charlotte Bobcats.
Key matchup I: LeBron James vs. Paul Pierce. This is the fifth time those two will duel in the postseason, Pierce (with Boston) ending James' season (with Cleveland) in 2008 and 2010. James, after joining the Heat, returned the favor with Miami topping Boston in 2011 and 2012. There's no question who the better player is today, but Pierce has a knack for coming up big at the biggest time of year.
Key matchup II: Wade vs. Joe Johnson. When Wade is good, Miami tends to be great, and Wade says he's feeling good physically after getting more time off between rounds. Johnson had 13 points in the final 12 minutes of Game 7 at Toronto, and if he gets hot, Miami will certainly have some headaches.
X-factor: Bosh. Miami is 38-12 this season when he scores at least 15 points, 19-14 when he does not.
Prediction: Heat in 6.
No. 1 SAN ANTONIO SPURS (62-20, 4-3) vs. No. 5 PORTLAND TRAIL BLAZERS (54-28, 4-2)
Season series: Tied, 2-2. Both teams won once on the other's home floor. The Trail Blazers won the first two matchups of the season, and one of the Spurs' wins came with Tim Duncan, Tony Parker and Kawhi Leonard all sitting out a game at Portland.
Story line: It's the veterans against the up-and-comers. San Antonio held things together perfectly after losing in last season's NBA Finals, finishing this season with the league's best record. The Spurs got taken to the limit by Dallas in the first round, while Portland got a buzzer-beater from Damian Lillard to oust Houston in six games — and the Blazers surely won't be feeling any pressure now.
Key matchup I: Tony Parker vs. Lillard. The guard play in this series could be phenomenal, and it starts with these two. Game 1 of this series will be Parker's 180th postseason game. Lillard hasn't appeared in that many games — regular-season and postseason combined — in his career.
Key matchup II: Tim Duncan vs. LaMarcus Aldridge. There might have been no better player in the first round of the postseason than Aldridge, who averaged 29.8 points and 11.2 rebounds in the six games against Houston. Duncan, though, is still widely considered the gold standard when it comes to post play, especially in the playoffs.
X-factor: Danny Green. The San Antonio sharpshooter was enormous for the Spurs in last season's NBA Finals, his 3-point barrages giving Miami fits. If he gets remotely close to that hot again, Portland will have to take attention away from Duncan, Parker and Manu Ginobili — which plays right into San Antonio's hands.
Prediction: Spurs in 6.
No. 2 OKLAHOMA CITY THUNDER (59-23, 4-3) vs. No. 3 LOS ANGELES CLIPPERS (57-25, 4-3)
Season series: Tied, 2-2. How close was it? Combined score: Thunder 432, Clippers 428. Oklahoma City won once in Los Angeles, the Clippers won once on the Thunder's home floor. They've met only once since Feb. 23, and that was the Thunder winning on the road 107-101 in a game that helped Oklahoma City lock up No. 2 in the West.
Story line: For the Clippers, maybe this series will have some sort of sense of normalcy. After the unbelievable roller-coaster of Round 1 — a fierce series with Golden State, the lifetime ban of the team's owner over racist comments — dealing with the widely presumed MVP in Oklahoma City star Kevin Durant might actually seem like a welcome change of pace.
Key matchup I: Russell Westbrook vs. Chris Paul. Westbrook is as explosive as can be, and Paul is physically banged up with who-knows-how-many injuries along with a certain emotional toll over the Donald Sterling mess. When these guys go 1-on-1 in this series, the highlight reels will fill quickly. It's also worth mentioning that Paul has never been to a conference finals, and it's a safe bet that's weighing at least somewhat on his mind.
Key matchup II: Durant vs. Everybody. No one person can successfully guard Durant, and Clippers coach Doc Rivers won't disagree. It's going to take a collective effort, of course, but this is why Rivers went to the Clippers — to find a way to take championship-caliber parts and turn them into a championship team.
X-factor: Jamal Crawford. He scored 36 points in a win at Oklahoma City back in February, and comes in riding high after scoring 22 points in the Clippers' Game 7 victory over Golden State.
Prediction: Thunder in 7.


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Both Sides Now
Many Paths Bring People to Research
Why I Work in Research
In U.S. hospitals, nurses keep medical records in fairly understandable English -- well, maybe more Latin than English -- but despite the jargon, a patient's story is told with words. Research nursing is different. Research medicine has its own system of numerical codes to account for almost every conceivable medical event that a patient might experience while on a study. Every ache, pain and rash, every drug consumed, every lab test blip, whether related to HIV or not, has to be carefully coded and recorded for as long as a participant is enrolled. It's the perfect job for the hopelessly anal-retentive. That's why I love it.
A good research coordinator has to be incredibly conscientous about details when preparing for a patient's visit, while meeting with the patient, then just as painstakingly thorough about doing the paperwork afterward. Everything recorded goes into the computer at the data center, where it is checked for consistency. For example, if someone in an HIV trial has a motorcycle accident, the date of the patient's back injury and lacerations must coincide with the dates that antibiotics and pain medication were given. If it doesn't, the computer spits it out and a trial monitor asks for clarification at her next scheduled visit. That's why everything must be put into the file while it's still fresh in the mind.
It took me many years to discover research. When I graduated from nursing school in 1980 there was a shortage of nurses and we had our pick of jobs. I decided to keep working on the internal medicine ward of the big-city public hospital where I'd received most of my training. We dealt with organ failure, autoimmune diseases and a wide range of non-contagious infections; the variety made the work interesting and challenging. But I especially liked being able to give care to people who couldn't afford to be treated by the other hospitals in town. Our hospital rejected no one.
After a couple of years, I moved to the renal transplant unit. Transplanting kidneys involves artificially inducing immune deficiency with drugs in order to prevent tissue rejection. On this ward I became familiar with several unusual infections such as pneumocystis carinii pneumonia (PCP) and cytomegalovirus (CMV) that transplant patients often came down with when their immune systems were suppressed. Oddly, we started to hear that on the East and West coasts, certain non-transplant patients were also developing these rare infections. At first, the "gay plague" that was terrorizing San Francisco and New York seemed remote. But soon, doctors began talking about the "4H"s that seemed to be susceptible: homosexuals, heroin users, hemophiliacs, and Haitians.
Since I had several gay male friends, I paid close attention. One friend in particular started to develop certain suspicious symptoms such as enlarged lymph nodes, shingles, and weight loss. Despite my alarm, common sense told me if this syndrome was only showing up in these specific populations, then it was probably not spread by casual contact. So when I heard that nurses had left meal trays outside the door of a patient with Kaposi's sarcoma, I transferred back to internal medicine. I welcomed the opportunity to dispense care where it was so clearly needed and I wanted to learn more about the syndrome that was still being called GRID (gay-related immune deficiency). Within a few years the syndrome had a new name, a causative virus had been identified and many of my friends and acquaintances had tested positive. Sometime during that period, I too seroconverted.
I worked on the internal medicine ward until 1993, compulsively keeping a list of the names of my patients who had died. When I finally decided to make a change, I took a job at a small outpatient infusion company run by two women, one of whom had lost her brother to AIDS. But when HAART came along bringing the miraculous "Lazarus effect" in 1996, that business began to fail and I cut back to working just a few part-time hours per week.
One day the director of a community-based organization where I volunteered asked me if I could come over and "help out" in their small research clinic. I agreed, though with some hesitation, since I knew nothing about research nursing. The clinic had been contracting with pharmaceutical companies to conduct Phase III drug trials, but after a period of downsizing, only one research nurse remained. I jumped right in, learning the ropes from him and from the site monitors sent by the drug companies. Before long I realized I'd found heaven. I loved everything about research! Not just because I'm naturally obsessive about details, but also because I rediscovered the joy of providing people with cutting-edge treatments, lab tests, and medical visits -- at no cost to them! Plus, the new drugs were working. People looked and felt better. It seemed research was finally paying off.
Entering the world of research during the advent of protease inhibitors also meant that my contact with the dying diminished. Fewer people with HIV were getting desperately sick, and the volunteers in the trials I was coordinating tended to be at earlier stages of their HIV disease. I was thankful and excited to be a part of something that had the potential to slow or possibly stop the devastation that I'd seen so often in the past.
It was only later, after I learned that resistance develops when inadequate doses and drugs are given, that I realized with horror I had been complicit in decreasing some people's options by doling out each new drug, one at a time, as it came on the market. I still have a lot of anxiety when I imagine that something we learn in the future might tell us that something we're doing now is wrong.
After about three and a half years in the little community-based clinic, I moved to the infectious diseases clinic at a larger, busier university medical center, which is where I work today. Though I ended up in research by accident, it feels like a more honest place for me to be. Instead of saying, "Take your medicine; it's good for you," I can comfortably tell people that, "this is a new product or a new combination and we don't yet fully understand what the risks and benefits might be. Thank you for helping to find out."
Why They Volunteer
Over the years I've learned that people choose to participate in research studies for many kinds of reasons. I recently got in touch with some former and current "lab rats" to ask them about their experiences. No research study can benefit everyone, but in general I've found that when people are well treated and they understand the risks, they have had positive experiences. Even so, not everyone had an easy time of it.
Not a volunteer in the strictest sense, Mike was barely a teenager when he began taking walloping doses of the only AIDS drug available at the time, AZT. He didn't tolerate its toxicities very well and had to have repeated blood transfusions. A few years later, he enrolled in a trial and started taking ddI. This was when it came in a packet like Carnation Instant Breakfast.
"I remember the ddI was extremely disgusting," he recalls. "Almost so bad that I'd rather die of AIDS than take it! I remember throwing up the ddI most of the time, but NOTHING was as bad as those high AZT doses.
"I don't really remember much from around that time. From the age of 15 to 21, everything is really jumbled -- I guess it was a period of stress or something," he laughs.
"It's never comforting knowing you're a guinea pig but it would be nice to be informed why certain drugs smell like gasoline and make your mouth numb. I understand the contribution of drug trials, but I don't like taking these drugs. Of course, nobody does."
Mike can't forget the role the pharmaceutical companies played in distributing blood products to treat his hemophilia during the years when HIV was clearly in the blood supply. He also recalls how the distributors and the FDA remained silent. "I feel completely helpless relying on drug companies that seem like they have had more experience trying to kill me than trying to help me. It's like my health just doesn't compare to the value of their stock."
Another experienced research participant I spoke with has a long track record of helping others in the HIV community. For Mark, joining a research study seems to have been a natural extension of his volunteer instinct.
The first clinical trial Mark participated in investigated treatments for staphylococcus infection. "I was just recovering from a surgically caused staph infection. [The principal investigators of the study] came to me and said, 'We don't want to pressure you, but...' They asked me to please consider their study. [Ultimately] the study was discontinued. I still don't know if I was getting the real drug or the placebo."
Even so, when asked if he felt the experience benefited him, Mark replied, "Yes, I think so. If nothing else, I was contributing to the gaining of knowledge. Participating in studies is one small way I can [pay back] the privilege of being taken care of by the medical community. And it takes studies to find answers. Information is power."
While altruism is a remarkably common, yet undervalued, motivation for participating in research, the best match between subject and study comes when the research addresses an unanswered question that will not only help society, but can help the volunteer's situation as well.
Currently Mark is in a trial to study the usefulness of phenotypic resistance testing in constructing treatment regimens. He needed to switch drugs because of virologic failure and because of toxicity. "One of my drugs was destroying my liver. They ran a phenotype and found out [my virus] was resistant to every [antiretroviral drug] out there. [They found the least resistance] to two drugs and they put me on those. And I'm on open-label tenofovir. But this study [continues] whether I'm on meds or not."
Mark feels that he is benefiting from this trial as well. "They found a combination that hopefully will be working. I don't go in for my first labs [for a couple of weeks yet]. I'm assuming they'll be working! I believe in the theory of positive thinking."
Participation in research doesn't take the place of comprehensive medical care. Although the principal investigator of a trial is, on occasion, required to examine research volunteers, that physician is not directly responsible for medical issues not related to the study. Study participants need to keep seeing their primary care providers on a regular basis. A big part of the research coordinator's job is to ensure that there is a flow of information between providers and the investigators. For instance, lab results collected for the study can be shared with a patient's provider at no expense to the patient, his insurance company, or to federal Ryan White Care Act funds. When the protease inhibitors first appeared, the reimbursement issue was a big incentive for many people to join trials, especially those who lacked insurance or were afraid to use the insurance they had. With the various AIDS drug assistance programs (ADAP) in place, that's become less of a motivator.
Then as now, a major incentive for joining a study is the hope of gaining access to an experimental drug before it's approved. But this is never a certainty. Since research studies need to create a difference between how groups of participants are treated, no one in a randomized trial can be guaranteed access to a particular regimen. For people with limited choices, expanded access safety studies may offer a better shot at getting a desired experimental drug. Unfortunately, expanded access programs are rarely large enough or started early enough to fully meet everyone's need for new treatment options.
Time and again though, research volunteers often say that the most important health benefit they receive from being in a clinical trial -- over and above the value of an experimental drug -- is the close and careful attention they get from the research staff. As Mark pointed out, "The sheer fact that I'm on a study, I feel I get closer medical attention, and for that I'm very grateful. To be on a study is actually easier for me than going to my regular doctor -- it's less stressful. I'm not in the same waiting room with the mass of people going to see the clinic doctors. It's almost like you're getting VIP treatment."
As is evident in the next case, joining a research study can open doors to a quality of care unimaginable at a local clinic.
Gerri and Jason
Gerri was first alerted to her own HIV status when her son, Jason, was diagnosed at three months of age in 1989. At diagnosis, Jason's physician referred the family to several larger cities in a quest for care, since AZT was not available for babies at that time. Jason was unsuccessfully screened for three studies before being enrolled in a trial at the National Institutes of Health (NIH), in Bethesda, MD. He finally received AZT oral suspension, his prognosis improved and he lived for two and a half more years. He participated in a second trial that, as Gerri recalls, involved an IV pump, but this did not help him. "It's the luck of the draw," postulates Gerri, "Some things work and some things don't." With pride, she says, "Jason was a pioneer. At least we had hope; at least he had a chance. We learned a lot about what [medicinal therapy] can do and what it can't."
In 1990, while staying with Jason at Children's Inn, a home-away-from-home for children being treated at NIH, some of the other mothers suggested that Gerri look into NIH trials being conducted for adults. "At the time, I was just on AZT and was getting anemic and tired. I had no energy, wasn't looking good, and was losing weight. I checked into a ddI trial and was accepted."
The ddI product was the same stuff Mike took -- a powder she had to mix with four ounces of water. "I mixed it with warm water because it seemed to dissolve better and I took it on an empty stomach. Carrying it back on the plane, I had two huge boxes of ddI. I didn't want to check it; I wanted to have it with me."
Gerri believes the research benefited her: "Most definitely. My blood work [improved]." She feels that the extra medical attention she got by flying to NIH every six weeks worked to her advantage although it was tough. "The travel was draining me. It was exhausting, but I would say it helped me because they would collaborate with my physician.
"There's the social part of it, too. Most of the people I met were men, and they were gay. It was a lot of fun. I enjoyed seeing the same people who were on the same schedule. We learned from each other. I got to realize that I wasn't alone. It was very important for me to know that I wasn't going through this by myself. Some of their stories were actually worse than mine, [with] the discrimination they had seen. We looked each other up when one of us was sick, or one of our kids was sick or had died."
But when ddI was finally approved, her support system ended. "The ddI trial was discontinued due to lack of government funding. They decided not to do any long-term trials; they were only going to do short-term studies. Videx was approved by then, so I could go back home and be seen by my doctor and receive the same thing. But I missed the adventure; being tied down at home as the caregiver, it was my one chance to escape and have fun. I was working as a peer educator at the local AIDS foundation and my brother was dying [of complications of AIDS], so I lost most of my contacts. I was very upset, knowing that I wouldn't see my [NIH] friends anymore -- the health care workers in addition to the patients. I felt I was losing family members."
Gerri later joined another trial in her community. "I had oral hairy leukoplakia and I became a participant [in a trial] to treat that. I liked it because it was herbal, and it worked."
She also entered a major pharmaceutical study: "I tried all the approved drugs. The last trial I participated in was Kaletra. I'm still on it and my viral load is undetectable and my T-cells are on the rise. Although the virus is not progressing, I am seeing some side effects from being on a triple combo -- 'protease paunch' and my veins are prominent."
Yet she still has reservations about the kind of studies she would feel comfortable with. "I would only participate in Phase III trials; I wouldn't have the guts [to volunteer for earlier phase trials] unless I was desperate. Right now my viral load is undetectable for the first time in my life so I wouldn't want to risk that . . . and I have more of a reason [to be careful] since my daughter has been born."
Gerri's two-year-old daughter, Alaina, has been a trial participant, too. "When she was born, she was given a one time dose of nevirapine, but she continued taking oral AZT [until they knew she wasn't infected]."
Gerri is open to joining other research studies in the future if they'll have her. "There is a Serostim trial going on, but they don't provide transportation and they say I don't have enough wasting. It's very frustrating when trying to enroll in studies because they only want people who aren't too healthy or too sick. Mainly they want more healthy people in the trials because if you have healthy people, you're probably going to have more promising results than if you have sick people.
"The other frustrating thing that I've seen related to clinical trials is that there are far more men participating than women and someone needs to take a look at why. I suspect that women are more in the caregiver kind of role. They make sacrifices every day, taking care of their husbands, their family, their children, and they always put others first."
I asked Gerri if she had ever been in a study that didn't benefit her. "No, trials work to a degree. After a while the drugs lose their efficacy. I envision them as lily pads, and when one starts sinking, you hop on another one before it starts sinking, hoping one day that you reach dry land. I think subjects know that they are human lab rats and that [no one can] guarantee that the trial is going to help. Hopefully people won't look at it as a guarantee, because nothing's guaranteed in life except death."
I asked Gerri where she thinks she would be today without research. "I wouldn't say there's no doubt, but I probably would have been dead. Research hasn't cured me, but it has given me my life back."
Why We Keep Showing Up
These stories illustrate a few of the ways that research has affected and has been affected by real people living with HIV in the United States. Mike, Jason, Gerri and Mark represent only a snapshot of those who have extended themselves -- sometimes in desperation, sometimes when there were less risky choices -- to help discover what a new therapy has to offer. They have taken risks, and as with all things uncertain, sometimes they have benefited and other times they haven't. But, like volunteers in most trials, they made a contribution to the body of knowledge that has brought HIV treatment to its current state and will hopefully continue to provide better options.
As for me, I'm continually impressed with the dedication people demonstrate when they volunteer for clinical trials. They show up for research clinic visits in addition to keeping appointments with their regular health care provider. They sit patiently while I ask an endless number of tedious questions and, in most cases, collect multiple tubes of blood. Together, we wait anxiously for lab results and have an ongoing dialog about whether this study is helping. Though we rarely say so, I think we understand each in our own way that helping to move research forward is the best chance we have to make sure no one else has to go through what Mike and Gerri and Jason did.
Back to the GMHC Treatment Issues October 2001 contents page.


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Long Noncoding RNA Database v2.0:
The Reference Database For Functional Long Noncoding RNAs
Blast lncrnadb
The lncRNAdb - Database that provides comprehensive annotations of eukaryotic long non-coding RNAs (lncRNAs).
23 Nov 2015 : Added carmen entry to lncrnadb, updated UCA1 entry.
29 Jan 2015: Added munc entry to lncrnadb
28 Jan 2015 : Added sencr entry to lncrnadb
27 Jan 2015 : Users can now obtain all sequences found in lncrnadb by downloading the csv file from http://www.lncrnadb.com/tools
07 Jan 2015 : Added lncsca7 entry to lncrnadb
Entries are manually curated from referenced literature. Each entry contains references information about the RNA including:
- nucleotide sequences
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- gene expression data derived from the Illumina Body Atlas
- structural information
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To search the database:
- enter a lncRNA name or allias into the text search tool
- enter a nucleotide sequence into the BLAST search tool
- set species filter ( if needed )
- browse the database by choosing the 'Browse tab'.
To submit an entry to the database please find the 'Contribute' tab.
For citations:
Quek XC, Thomson DW, Maag JL, Bartonicek N, Signal B, Clark MB, Gloss BS and Dinger ME (2014) lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs. Nucleic Acid Res 43: D168-D173
Amaral PP, Clark MB, Gascoigne DK, Dinger ME, Mattick JS (2011). lncRNAdb: a reference database for long noncoding RNAs. Nucleic Acids Res 39: D146-151.
For Queries:
For the fastest response to any queries, please contact lncrnadb at email@example.com
lncrnadb version 2.0. lastupdate : 03 Sep 2015


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This is a really groundbreaking month on the jobs report.
If you've been following things for the last couple years, you'd know that the private sector consistently adds jobs, but that the state and local sectors bleed jobs.
Well, look at this table from the BLS. If you look down at the very bottom at the cells highlighted in blue, you'll see that state and local hiring actually added 1K jobs from January to February— the first positive number in ages.
For what it's worth, we predicted the end of state and local austerity last month, when Chris Christie was trumpeting tax cuts and investment in education in New Jersey.


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Nobel Winner's Contribution Questioned
A coauthor of the key paper that led to one of this year's Nobel Prizes for Physiology or Medicine claims the recipient wasn't involved in the research.
Dec 19, 2011
Cristina Luiggi
A scientist is accusing French immunologist Jules Hoffmann, who was awarded the 2011 Nobel Prize for Physiology or Medicine along with Bruce Beutler for the discovery in Drosophila that the Toll gene regulates the immune response against bacteria and fungi, of not doing the research that led to the prize. The accusation comes from none other than the first author of the 1996 Cell paper where the finding was reported, Bruno Lemaitre.
Lemaitre, who worked as a research associate in Hoffmann's lab at the at the National Centre for Scientific Research (CNRS) in Strasbourg, France, from 1992 to 1998, claims that for most of the 1990s, he was the only researcher working on Toll and that Hoffmann did not express interest and was for the most part not aware of his research.
"Jules never provided any ideas for my project, being very far from the realities of experimental bench work…[and] was not very supportive of the genetics approach I had undertaken," Lemaitre wrote in a story outlining his take on the work the led to the Nobel. "Subsequently, he has never been able to fully recognize my contribution, yet somehow it is he who is now collecting the honours for my work." He published the story in a website he created to voice his frustrations on the subject.
Although Hoffmann refuses to address Lemaitre's accusations on account that it "would not be elegant," he told ScienceInsider last week that he "cannot feel any guilt at all," and that Lemaitre and others involved in the work received their due credit in the Nobel lecture he gave recently in Stockholm.


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Mason Desk Chair
Overview & Details
- Sleek and modern kids' desk chair.
- Seat is adjustable.
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- Swivel seat with curved back.
- Sturdy enough to grow with your child.
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Give your child a cool spot to sit while doing creative projects with the rustic styling of our Mason Desk Chair for kids. This awesome kids' desk chair is designed to be functional now and to grow with your child through the years. The cool design is guaranteed to be just as cool when he's older, too! The Mason kids' desk chair is made from solid wood and iron and features a swivel seat with curved back for comfort. Matching desk and accent table also available.


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Arizona lost quarterback Kevin Kolb, then lost its eight-game home winning streak.
Kolb was injured with just over two minutes left in Sunday's game when he tried to fall forward and two Bills players landed on him. He lay on the field for several minutes as medical personnel attended to him, then gingerly walked off after a cart was waved off.
Kolb lost a tight battle to be Arizona's starter to open the season, but started four games after John Skelton sprained his right ankle in the opener against Seattle.
Skelton, active for the first time since his injury, replaced Kolb in Sunday's game.
In Baltimore, the Ravens had two costly injuries - to linebacker Ray Lewis and cornerback Lardarius Webb. Lewis, the Ravens' emotional leader, hurt his triceps in the 31-29 win over Dallas.
Webb banged his knee in a first-quarter collision with Cowboys wide receiver Dez Bryant. Webb remained prone on the field for several minutes before being helped to the sideline.
The team originally labeled the injury a ``sprain,'' but after Baltimore's 31-29 victory, coach John Harbaugh painted a potentially darker picture.
``Lardarius Webb does not look good right now,'' Harbaugh said. ``It's a potential ACL. We've got a problem there. We don't know for sure, but that's what it looks like right now.''
Ravens safely Bernard Pollard added, ``That's what happens in this game. You hate to see a guy like that go down because he's worked his tail off. Our prayers are with him to get a speedy recovery, but the next man has to step up.''
Now in his fourth season, Webb has one interception, one forced fumble and a fumble recovery in six games this year.
Also in that game, Cowboys running back DeMarco Murray was removed with a left foot injury. He carried 14 times for 93 yards but did not get the ball after the 11-minute mark of the third period. The extent of the injury was not immediately known.
Vikings running back Adrian Peterson ran for 79 yards but at times was limping on his sprained left ankle against Washington.
Redskins S Jordan Pugh left the fourth quarter twice with a head injury. The Redskins say he was cleared to return after the first injury, then was diagnosed with a concussion after the second one.
In Sunday night's game, Texans defensive end Tim Jamison left Sunday night's game against Green Bay with a right Achilles injury and the team said he would not return.
The 6-foot-3, 285-pound Jamison played in each of the Texans' first five games, backing up J.J. Watt. Jamison had nine tackles, including a sack, and a deflected pass this season.
Packers linebacker Nick Perry left in the second quarter with a knee injury and was out for the game. Perry was the Packers' fifth-leading tackler (28) and had two sacks through the first five games. Green Bay middle linebacker D.J. Smith limped off the field later in the second quarter with a right knee injury and also was out for the game.
Texans right guard Antoine Caldwell left before halftime with a concussion.
Packers running back Brandon Saine injured a knee playing special teams.
Earlier, the Jets lost two running backs in four plays.
Joe McKnight was hurt on a 61-yard run, three plays after Bilal Powell was lost with a shoulder injury. Both McKnight and Powell were scheduled to have MRI exams Monday.
San Francisco left tackle Joe Staley left with a concussion in the third quarter of Sunday's game against the 49ers.
In Cleveland, rookie running back Trent Richardson was hurt when he took a helmet to the side early in the game, but the Browns got their first win of the season anyway, 34-24 over the Bengals.
Richardson finished with 37 yards on 14 carries and spent most of the second half on the sideline. But Richardson's backup, Montario Hardesty, picked up the slack and rushed for 56 yards and scored his first touchdown in the NFL as the Browns (1-5) also snapped a 12-game losing streak inside the AFC North.
``I took a shot, but I'll be back,'' said Richardson. ``I'll be ready for next week.''
Online:http://pro32.ap.org/poll andhttp://twitter.com/AP-NFL


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Or the Koran, etc. etc.
My choices would be,
1. Alice's Adventures in Wonderland/Through the looking glass and what alice found there. By Lewis Carroll
2. The Complete Hitch-hikers guide to the galaxy, by Douglas Adams.
3. Cats Cradle, By Vonnegut Jr. (Or almost anything by him, also particularly Sirens of the Titans)
What about you? What book or narative do you think presents a better understanding of Morality/reality/sexuality/ and/or spirituality, then the trash presented by the pig religions?
Views: 1862
I disagree that the question posed is "negative".
"Replacing the bible", especially for children would promote tolerance, diversity and coexistence, yes the hallmarks of atheism. Children trust that adults teach them the truth. In short order it becomes too late and the result is the spread of AIDS, guilt, poverty, hate, suicide bombing, child molestation, subjugation of women, suppression of learning and science, hording of wealth, mind control, religious wars...etc, etc....
After all, they will be forgiven...that is all they really care about.
Do you think it is ethical to tolerate and coexist with people like that?
Indoctrination of the young is crucial to the survival of religion and the power it yields. This is why "baptism" of babies is such a big deal..so much so that "John the Baptist; he is risen from the dead". Ol john, it seems is a mini jesus.
Nope don't you dare wait for that kid to grow up and decide for him or herself. Heaven forbid if something should happen to them the mean time. Imagine the guilt !
@Robert - and they're blind to the issue of what kind of god would burn a baby for eternity.
I'm definitely against burning babies (and/or otherwise killing them). And I cannot imagine a true Creator who would roast anyone on a spit for eternity unless they had it coming.
Isn't indoctrination of the young crucial to atheism?
Hardly, Glen C. - it's hard to get them much younger than newborns, and all babies are born atheist. It takes indoctrination for them to be otherwise.
'..all babies are born atheist..'
All babies are also born none english speeking. Not able to solve differential equations. Non-political. Unable to hold their poop! etc.....
I wonder if being an 'atheist' is dependent upon the ability to make choices? Can a baby make choices? If my child developement class was right, 'choices' would be a higher function, that might not develope till a little latter than birth.
I expect that babies are bundles of poop and joy, not atheist insight. I could be wrong...
It's not a matter of choices, James, when it comes to what you're born with - no baby chooses whether it will be born with one arm or two, and no baby chooses whether or not to be born with a belief in a god.
Which do you believe it is, James, are babies born with a belief in a god, or without? Pick one, it's that simple.
I wish to suggest that 'babies', are not fodder for atheists, theists, or Buddists. They just are.
As I grew up, I was surrounded by Catholics, Lutherians, JW's, etc. I did not find out about 'atheists' till I started to question my families metaphysical commitments. I cut my eye teeth on Russell, Plato's Dialogues, family death, and exposure to the sciences starting about 12 years of age.
If I had been raised within an atheist household, I might have not had my divergence. My family did not denigh me exposures to other ideas, and partly encouraged my science interest. Both my parents were poorly educated, but my mother was a writer and reader. My father mostly killed things hunting and fishing it seemed.
Claiming that babies are 'born atheist', seems a little odd to me. I figure that we all become something over time. With a very large social list to pick from, either via a conscience choice, socialization, or process of discovery.
I expect that babies don't think to themselves early on, 'wow there can't be a god, I must be atheist!' They are very happy to have a tit, a clean bottom, a soft bed, and many square meals a day. 'Look Who's Talking' not with standing....LOL
@James - possibly you should refresh your memory regarding the definition of the word, "atheist."
If you disbelieve that babies are born atheists, could you please enlighten us as to which theology you believe they're born into? And don't worry about evidence, I'll settle for your opinion.
Ah a little better question.
As my opinion, I would like to suggest that babies are not born with a 'belief', but only needs and growing abilities. Theist or atheist, these commitments emerge out of exposure to culture and a growing understanding about the world. When it is said, 'Babies are born atheist', the underlying assumption is that babies are born issolated from a social or worldly context, and that their early cognition is established, neither of which is true.
While looking in from the outside, we could say that 'babies appear born with no commitments to social norms/customs/beliefs', a lable such as 'atheist' or 'theist', can not be imposed because the child's cognitive endowment is not yet ready to form these. While I agree that people can form these over time, sometimes rather early in life, it seems very premature to suggest that new borns are capable.
Looking back at my own cognitive maturity, I notice a slow increase in my ability to manage details about culture and the world. Being taken to a catholic church early on, felt very alien, and the statues, symbolism, etc, rather unreal.
I feel a growing disconnect between my experiences with the world and the church. The natural world being so much more interesting. My best early memory comes from times playing with snakes in the church play ground, looking at life in the local ditch, and collecting insects. After I received a telescope and microscope for xmas, I was off and running, never to return, except to test my commitment to the outside world and away from church. Tracking the moons of Saturn when about 9, I consider my actual break point, but I needed about 20 more years before I could say 'sorry church'.
While my present commitment is to an atheist position, I know that the 'truth' might be bigger than any 'ism' can contain. The absence of 'god', seems most likely, and at present, I can find no reason to renew the status of this hypothesis to 'possible'.
It is possible that the above does not meet with your acceptance, but it seems the the best I can do at present. I am only 58 this year, just a youngster in comparison to the mountains and stars...
I don't understand, James, what there is about this issue that makes it so complex for you. Either a child is born with an innate belief in a deity, or it is not.
If it is, then it must follow that raised in relative isolation, with no religious influence whatsoever, he/she will, of necessity, according to the extrapolation of the premise, automatically grow up with a belief in a supernatural being.
Otherwise, the child is born without a belief in a deity - a theist - it's no more complex than that. I've never known you to be devious, so I can't assume you're putting me on, just as - unlike Unseen - I've never known you to be argumentative, just for the sake of argument. I just can't understand why the issue is so complicated for you.
I'm not at all upset (which is sometimes not easy to communicate in written form), just trying to understand.


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Sunday December 23, 2007 2:25 pm
2007 Holiday Gift Guide: Hamilton Beach Ensemble 12-Cup
Posted by Andru Edwards - Categories: Features, Smart Home, Family, Women, Men
If you are looking for a great gift for the coffee fan in your life that isn't terribly expensive, you should consider the Hamilton Beach Ensemble 12-Cup. This is a product that might make even those who have switched to lattes give drip coffee another look. Don't let the shiny exterior and low price fool you - the Ensemble 12-Cup hits you with rich, smooth brew. It it also compatible with an optional water filter, which costs $10, for those who want to make sure their water is clean. It's available in both black and red. These retail for $49.99, but you can find them cheaper by shopping around.
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Contractor to U.S. Army: Give Back Our $300M Blimp
After the military canceled a $300 million spy blimp project, the contractor wants it back from the Army. Dion Nissenbaum has exclusive details. Photo: Getty Images.
This transcript has been automatically generated and may not be 100% accurate.
... the the ... so who spent nearly three hundred million dollars on a whim and then gives it right back to its maker ... our very own U S military that if the plants maker Ken persuaded to do so ... Diana SnB on in Washington has the exclusive on the ill fated airship Diane thanks so much for coming and joining us this morning ... the problem until that is that is ... the football field size ... that plan ... it is is she huge huge project ever going to spend five hundred million dollars on as planned ... um it was meant to be stated with all kinds of ... surveillance equipment that they could upload over Afghanistan ... but with the war in Afghanistan winding down the Army decided that they didn't need it anymore and they sent it off ... they decided to to cancel it ... and that when they put it in to the scrappy decided to cancel last month it makers said well if you just couldn't do nothing but it will give it back to us ... CP can find something else to do with the publishing ups buyback ... well you know that's a question to lambaste ... the army there the error is not going to say but they're wet weather Forstall the willing to do this ... the companies are saying what exactly they're going to pay for an obviously ... I think ... that's the big question company officials are telling us well to get up their hands they will have to pay for storage ... that is arming and won more than that a I think ... that's the could be the crux of the issue ... was this the first of its kind ... I've that is the isthe us ... as the U S Army Air France's he did look like in the army is stamped on there as the US military ... ever had a plan of this kind ... this was a system in animated up new project we have a much smaller Sir Winston surveillance things that she ... sometimes they have on the border as well ... but there's there's been nothing of this size and that's why ... the company wants wants it back because it is is pioneering ... and they wanna see they don't wanna just have all of this investment and research that that that Danone etc go down the drain in ... an event that this is this is the best of two ... larger ones they used to transport heavy equipment and they wanna they wanna make sure that that that they're ... essentially can can stay in business and I don't want to roll their ... their research and development to go down the drain but at this time is the play to them and put in storage deflated ... soon speed ... um so though ... and ultimately they they really want it sounds like the Canadian energy companies ... big they think they can sell it to them is that the plan ... that's that's great is this company I read her vehicles which is in Britain they're looking to Canada because they think that convinced him to events that oil gas mining companies to use these out to get to transport heavy equipment into remote area so they're ... they're they're only have been ... sort of general interest from and now they don't have any firm commitments or anything like that but ... it is a big investment for them and they really can just see it ... I'm you know disappear ... it's a and and let it ... go away without trying to salvage it and John McCain was one of the biggest critics of the present correct ... McCain was critical of ... the army stand all this money and letting it go so far ... I'm not canceling it earlier if they ... manage to keep on track ... and yet it Afghanistan well the war we're still going on weather searches going on and off the Cuban and critical but ... in his argument was that the Pentagon spends too much money on ... projects like this let them get out and and stands three hundred million dollars in him and then pull the plug ... on


text:
von Chactory » 21. Dez 2008, 13:57
von Rein » 13. Dez 2008, 17:29
However, I can also appreciate that there are lots of users of spami who are new, and so have no history to draw on. And I can appreciate that there are lots of users who don't understand, as yet, exactly what all the filters do. And so, a recommended list of filter priorities could be useful.
von Zaxon » 17. Jun 2005, 08:29
michel hat geschrieben:God job! Very well done.
von michel » 16. Jun 2005, 19:00
von Zaxon » 16. Jun 2005, 09:16
Ian hat geschrieben:Having put my request in for a filter priority list I then uninstalled Spami and decided to use the spam filter in Thunderbird.However, having seen your kind, informative responses I am now back with Spami.
von Gast » 16. Jun 2005, 04:42
von Bob Loeffler » 15. Jun 2005, 19:14
von Zaxon » 15. Jun 2005, 19:11
Bob Loeffler hat geschrieben:This topic is now a "sticky" note. Bob
von Bob Loeffler » 15. Jun 2005, 18:15
von Zaxon » 15. Jun 2005, 16:31
Andy hat geschrieben:Ahhhh I SEE All clever stuff, as I said before (sory to be boring) if there was some proper decent help files that explained how things work there wouldn't be the need to keep posting on the forum.Just a suggestion but your posts are so informative and helpful is there any way they could be 'set up' at the top of the forum as READ ONLY posts for the important matters, such as the filter priority settings, UNDERSTANDING the default settings etc.I'm sure it would be VERY helpful to alot of people and save your time keep going over the same Main topics again and again or worse still your 'hard work' dissapearing into Forgotton Forum history !If you can't do that yourself and Michel reads these Forums then YOU do it please, great program but do yourself a favour and let people understand how it works PROPERLY.You made it so you know but we aren't all PC experts
von Gast » 15. Jun 2005, 10:44
von Zaxon » 14. Jun 2005, 14:52
Andy hat geschrieben:Thanks for that very informative and helpful as normal
Andy hat geschrieben:I'd just like to say (I know I'm probabaly talking rubbish but it works for me! ) I just couldn't understand the default filter settings..'If a filter finds a NON spam mail stop filtering''If a filter finds a SPAM mail stop filtering'Either way it's going to stop filtering (in my 'eyes') and never go on to the next one...Even though I don't get huge amounts of spam I was gettings loads through every day so I changed the default settings to...'If a filter finds NON spam continue to next filter''Spami' now works SUPERBLY 100% SUCCESFULL so far since I altered the settings, I don't care if that's wrong it works for me on my PC
von Gast » 14. Jun 2005, 10:59
von Zaxon » 14. Jun 2005, 09:32
Ian hat geschrieben:Thanks for that.Could I ask you to list your filters in order. I'm willing to bet there are a lot of people like me that want a standard product to highlight spam. I'm not too worried about getting that extra 1% accuracy at this moment in time - I'm happy to kill spam: full stop.I need somebody to say I use these plug-ins in this order and it works for me. As time progresses and I get used to the programme I will make changes myself. For instance, how do I know which filters work the best??Spami has a great reputation. However, as a new user to be offered a big choice of filters and not being sure what to do probably loses Spami some users. It's nice to have choice when you know what you are doing, otherwise, you go with a product that can't be customised and make do.
von Gast » 14. Jun 2005, 00:19
Nach oben
Copyright © 2002-2012 Michel Krämer. Alle Rechte vorbehalten.
Valides XHTML 1.0 Strict


text:
Conference "Architecture and Cities for the 21 Century"
Valencia, July 1998
By Minja Yang
As the century approaches its end, the oracles of the day have set about prophesying doom or utopia in the next millennium at conferences, in the media and even in board rooms where marketing strategies are developed for just about anything from soap to satellite dishes. After a century of unprecedented commodities production through the massive and often unplanned exploitation of natural resources, a new fin de siècle malaise, as it were, is setting in. The shift from production-based economic growth to speculative financial "engineering", widespread unemployment in the West, the delocalisation of production centres to developing countries, and post-Cold War international relations have all contributed to the sense of uncertainty. Globalisation in practically every field subjects individuals to forces that are increasingly beyond their control. Even though wars have been fought and blood spilt for the noble causes of democracy and human rights, people today, ironically, may have less say in their own destinies than they did at the turn of the last century. These and other factors have turned environmental issues into matters of direct concern to the individual as well as the State. For most people the overriding concern, however, is not how to save Planet Earth, but rather how to improve the immediate environment in which we live.
Most ordinary people spend the bulk of their lives moving from one building to another, travelling ever-increasing distances in cars, buses, trains or on foot, with more and more chores to carry out in less and less time. Individuals find that their quality of life, whether in the developed world or in developing societies, is conditioned by the quality of the environment being built around them by others - increasing the sense of individual alienation, especially among the underprivileged.
Rapid urbanisation is expected to continue, drawing two-thirds of the world population into cities by the next century. By the year 2030, the urban population in developing countries will be twice the size of the rural population. In some cases, urban sprawls will not only dominate a country's economic life but take up most of its physical space, turning it into a vast urban territory.
If the future of humanity is irrevocably linked to the city, then this future - political, economic and cultural - must be addressed from a global perspective but also at the local level. Following on from discussions of new ideologies, water resource management and human responsibilities at conferences organised under the Valencia Third Millennium Programme, the Conference on Architecture and Cities for the 21st Century will also have a global theme. But the aim is not to prophesy, nor to make international resolutions or even recommendations. The conference has no such pretensions. My aim, as general coordinator, has been to select a few issues that will animate the debate of ordinary people on architecture and urbanism today. Rather than making a tour d' horizon of the grand theories of urbanism or of the stylistic evolution of architectural design and its rationalisation, I have invited the guest speakers to describe the multitudinous ways in which they have tackled architectural and urban problems. If, within the limited time of two days, they share with us the professional lessons they have learned as architects, urbanists or local politicians in the development of cities, the ambitions of this conference will be fulfilled.
In presenting their work, the speakers will naturally address the fundamental questions of architecture - concerning the planning, design, construction and use of buildings - as well as the city as our human environment. The first theme of the conference, "Avant-garde and Heritage", encompasses a range of questions: How have landmark architectural projects contributed to the advancement of new building technologies or served in the transformation of social relations in the city? Have these and other public projects involved the participation of the people they are to benefit? How can new building technologies and architectural design contribute to environmental sustainability? Is new architectural creativity being stifled by the shift from a zeal for great architectural masterworks towards the appreciation of a historic sense of place and from the monumental to the vernacular under the changing philosophies of cultural heritage preservation? Is the tug-of-war between architectural continuity and architecture as rupture a false debate? Does cultural pluralism have any chance of survival against the growing domination of so-called international style dictated by mass produced building materials?
The second theme concerning urban projects and their dynamics focuses on the city as a human environment. Some cities' historic centres have been taken over by the elite, while the poor have been pushed out towards disadvantaged suburbs. Elsewhere, it is the middle class who monopolise the fashionable suburbs, abandoning the centre to the underprivileged. Property speculation and the resulting ups and downs of the real estate market threaten the city with cultural and social impoverishment. In the urban fringe, power plants, waste-treatment facilities, industrial parks and mega-sized shopping malls are further blighting and enlarging urban sprawls. Highways, railroads, bridges, tunnels and other transportation infrastructure have come to define the "cultural landscapes" of our times. Can such infrastructure and public equipment - clearly essential to our mode of life - be built in harmony with our natural environment to create a more convivial human environment?
The fortuitous invitation extended to me by Sra Rita Barbera, Mayor of Valencia, to organise this conference with a carte blanche regarding the selection of both topics and participants, and the authorisation granted by Dr Federico Mayor, Director-General of UNESCO, for me to devote part of my energies to this endeavour, gave me a rare opportunity to reflect on the issues I treat on a day-to-day basis. As the UNESCO World Heritage Centre exists to protect and conserve cultural and natural properties of "outstanding universal value" by promoting the implementation of the World Heritage Convention, we are called upon to help address a wide range of problems. Considering that nearly 150 of the 418 cultural properties on the World Heritage List are located in living historic cities, it is no surprise that the World Heritage Centre is reminded daily of the clash between heritage preservation and urban development. This need not be the case, of course, but in most cities, compatibility between heritage and development - let alone their inseparability - is no more than an elusive theoretical ideal. In the over-populated cities of the developing South, other than in a few "museum towns", the demolition of entire historic urban sectors, the abandonment of unique historic buildings, and the construction of new buildings that are incongruous, to say the least, with the integrity of the historic urban fabric are combining to transform the cities' very identity. Furthermore, work to upgrade roads and improve mass transport systems, while necessary, may unfortunately be done without due regard to maintaining the integrity of historic centres.
If the essence of heritage protection is to preserve the ingenuity of the past for future generations, as well as to stimulate new creations, heritage must have a meaning in contemporary society. This is a fundamental precept of the World Heritage Convention, contained in Article 5. For heritage preservation that denies modernity, that obstructs development, that attempts to freeze time, would be counter-productive to the ultimate goal of human progress.
Despite globalisation, the reality of each individual city is unique and complex. There are no "urban models" of reference, only case studies. I hope that the architects, urbanists and mayors who have kindly agreed to participate in this conference will demonstrate to us, through such case studies, the ways in which each city's future can be anchored in its individual identity. Let us all strive to protect and build an "urban heritage" as the basis for developing urban policies for the city of the future, the city of the new, democratic age.


text:
'For a compact camera, the Canon PowerShot G7 X can produce alarmingly good photos. '
'Plenty of special effect features to use. '
'Wide aperture zoom lens.'
'Great image quality from 1in sensor.Flexible '
'If you're in the market for a compact superzoom and you're on a budget, the SX600 HS is our recommendation.'
'logical controls'
'Creative Shot mode.'
'Shutter lag with flash is poor.'
'With such an impressive performance it's a shame the SX710 HS's image noise levels let the side down somewhat. '
The 30x optical zoom, inbuilt Wi-Fi and fun features could add up to the perfect holiday compact
Difficult to improve on our favourite 30x compact
42x optical zoom available with Digic 4+ processor
This camera packs a 24-1008mm zoom lens for serious close-ups
This is a camera for someone who finds they've outgrown their basic point-and-shoot and wants to start dipping their toe into manual settings.
Offering a 30x optical zoom in a pocketable package, the SX700HS might just be the perfect compact for travellers
Easily pack 30x worth of optical zoom in your pocket
Pocket-friendly it may not be, but what you get in the Canon PowerShot SX700 HS is a strong compact camera with a terrific long lens that produces great images and videos.
30x travel zoom overflows with features
Canon makes its latest tough compact a waterproof wonder
A reliable 18x zoom travel compact with a range of useful functions
While Canon's PowerShot SX600 HS is an easy-to-use camera with a long 18x zoom, performance and image quality resembles those from a lower-end camera.
Picks up where your phone leaves off without sacrificing easy sharing
Very good photos in bright light, and the fast lens, optical viewfinder
Larger-than-average image sensor, Sharp
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Built-in Wifi and GPS via a smartphone, 1080p60 HD video mode.
Raw support, 1080p60 video, 10fps continuous shooting
One of smallest cameras with RAW & manual control
Good handling, Excellent image quality, Fast and easy to use
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text:
This appendix is informative, not normative.
This appendix summarizes the changes that have been made since the SVG 1.1 Second Edition Recommendation. Changes made since the last SVG 2 Working Draft are highlighted.
A number of stylistic changes have been made to the specification to make it more readable. These include the following:
In additional to the editorial changes listed above, the following substantial additions, changes and removals have been made.
unsuspendRedraw and
unsuspendRedrawAll methods in the SVGSVGElement interface.
text-overflow' processing.
white-space' property and deprecated 'xml:space' attribute.
and '
marker-pattern' properties.
paint-order' property.
buffered-rendering' property.
vector-effect' property to support non-scaling stroke.
and '
solid-opacity', ported over from SVG Tiny 1.2.


text:
15 members4 Comments 1 Like
125 members44 Comments 6 Likes
94 members67 Comments 12 Likes
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230 members8 Likes
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52 members25 Comments 2 Likes
26 members16 Comments 4 Likes
95 members
377 members11 Likes
35 members39 Comments 4 Likes
239 members11 Likes
lol I don't mind let me get my Mic
Thanks for letting me know! I'm not sure what photo you're talking about?
Lol nice one! Maybe one day well actually get the chance to play each other I'm a 4.0 player though with a one-hand backhand but I can hold my own in a rally
Yeaaaaah..... I'll put some thought into that one. Haha you got jokes!
Posted on January 6, 2014 at 12:30pm 26 Comments 1 Like
Hi Everyone this is CoachV Over the last 5 years I have gained about 40lbs I went from a 165lbs to 205lbs. My performance on court wasn't really hampered much outside from an occasional cramping in the legs after a hard…Continue
Posted on December 2, 2013 at 10:48am 0 Comments 2 Likes
Posted on February 8, 2013 at 9:30pm 8 Comments 0 Likes
So i have been studying My Marketing materials again getting ready for this up coming tennis season.
I have a New baby Coming in August 2013 and I will need to get my business straight-er.
In my work book it says to simply ask your clients for a referral.
so Here I am Asking Tennisopolis if you…Continue
Posted on January 9, 2013 at 7:00am 1 Comment 2 Likes
1 year Birthday of Alex playing tennis, pictured from Left to Right
Brandon Gita, CoachV, Alex Smirin, Cade Lautenbacher.…Continue
Posted on December 20, 2012 at 10:30pm 1 Comment 1 Like
Time: March 4, 2013 at 9am to March 8, 2013 at 8pm
Location: Indian Wells CA,
Street: Courtyard Palm Desert…
© 2019 Created by Mark / The Mayor. Powered by


text:
The president's inviting Mitt Romney for lunch is a small thing but a brilliant move. It makes Mr. Obama look big, gracious. It implies the weakened, battered former GOP nominee is the leader of the Republican Party—and if the other party has to have a leader, the weakened, battered one is the one you want.
Mr. Romney is not the leader of the party; he left no footprints in the sand. There is no such thing as Romneyism, no movement of which he's the standard-bearer. Nor is he a Washington figure with followers. Party leaders already view him as a kind of accident, the best of a bad 2012 lot, a hiccup. The bottom-line attitude of Republican political pros: Look, this is a man who's lived a good life and would have been a heck of a lot better than Obama, and I backed him. But to be a successful Republican president now requires a kind of political genius, and he didn't have it and wasn't going to develop it. His flaws as a candidate would have been his flaws as president. We dodged a bullet.
Republicans may be the stupid party, but they're not the sentimental one. Democrats often like their losers. Republicans like winners, and they find reasons to be moved by them after they've won.
To the extent the GOP has an elected face, it is that of Speaker John Boehner. And he is precisely the man with whom Mr. Obama should be having friendly lunches. In fact, the meal with Mitt just may be a clever attempt to obscure the fact that the president isn't really meeting with those with whom he's supposed to be thrashing out the fiscal cliff.
At a news conference Thursday, Mr. Boehner looked frustrated. In fact, he looked exactly the way he looked at the end of the debt-ceiling crisis in the summer of 2011—like someone who wanted a deal, was willing to gamble to get it, and failed. There has been "no substantive progress" toward an agreement, he said. In a meeting with Treasury Secretary Tim Geithner and in a Wednesday night phone call with the president, he saw no willingness to reform or cut entitlement spending. What about an increase in tax rates? "Revenues are on the table."
In fact the Democratic position on entitlements seems to have hardened.
In a way Mr. Boehner's press conference was the usual, but in a way it was sad, because it harkened back to the protracted, harum-scarum and unsatisfying fiscal negotiations of the recent past.
The election is over, a new era begins—and it looks just like the old one. A crisis is declared. Confusion, frustration, and a more embittered process follow. This is . . . the Obama Way. Nothing has changed, even after a yearlong campaign that must, at times, have looked to him like a near-death experience. He still doesn't want to forestall jittery, gloom-laden headlines and make an early deal with the other guy. He wants to beat the other guy.
You watch and wonder: Why does it always have to be cliffs with this president? Why is it always a high-stakes battle? Why doesn't he shrewdly re-enact Ronald Reagan, meeting, arguing and negotiating in good faith with Speaker Tip O'Neill, who respected very little of what the president stood for and yet, at the end of the day and with the country in mind, could shake hands and get it done? Why is there never a sense with Mr. Obama that he understands the other guys' real position?
It's not as if Mr. Boehner and the Republicans wouldn't deal. They've been weakened and they know it. A year ago they hoped winning the Senate and the presidency would break the stasis. They won neither. Mr. Obama not only was re-elected, it wasn't that close, it was a clean win. If the president was clear about anything throughout the campaign, it was that he wanted to raise taxes on those he calls the rich. So you might say that a majority of the American people just endorsed that move.
No one would know this better than Mr. Boehner, who has risen to where he is in part because he's good at seeing the lay of the land and admitting what's there.
The president would only benefit from showing he has the command and capability to meet, argue, press and come to agreement. It would be heartening to the country to see this, and would impress the world. And the Republicans would like to get it done.
In narrow, purely political terms, they need two things quickly. One is that it now looks to everyone—even to them!—like the entire domestic agenda of the Republican Party is tax-cutting, and any party's agenda has to be bigger than that. The other is that when they try to protect people from higher tax rates they always look like Diamond Jim Brady enjoying the company of the wealthy and not noticing anybody else. Republicans need time to work through, within their party, their own larger economic stands.
So they're weakened, they want this particular crisis to end, and they badly need to win entitlement reforms that would, in the end, buttress the president's historical standing—and the president isn't working with them every day and making a deal?
* * *
Here's just one thing they should be discussing. Mr. Obama wants to raise tax rates on those earning $250,000 or more, as we know, on the assumption that they are "the rich." But if you are a man with a wife and two kids making that salary and living in Westfield, N.J., in no way do you experience yourself to be rich, because you're not. You pay federal payroll and income taxes, state income and sales taxes and local property taxes, and after the mortgage, food and commuting costs you don't have much to spare.
Tighten the squeeze on that couple, and they'll change how they live. They'll stop sending the struggling son to a neighborhood tutor, they'll stop going out to dinner once a week, they'll cut off the baby sitter, fire the guy who once a month does yard work, and hold back on new clothes. Also the guy will peruse employment ads in Florida and Texas, potentially removing from blue-state New Jersey his heartening, taxpaying presence.
It really is worth a discussion, isn't it? A closer look at the numbers? Shared thoughts on how Americans really live?
* * *
In an interview last year, shortly after the debt-ceiling debate, Mr. Boehner spoke of how much he'd wanted a deal. He wanted entitlement reforms, cuts in spending, was happy to increase revenues through tax reform. He thought our fiscal realities the great issue of his speakership, said he meant it when he told staffers if it resulted in the end of his speakership then so be it. He'd have walked out of Congress knowing "I did the right thing."
That's who Obama should be negotiating with—in good faith, and with his eye not on ideology but on the country.
Instead, it's going to be a long four weeks. Scratch that, it's going to be a long four years.


text:
Canada & New England
Feel the crispness in the air that heralds a change of seasons among Canada and New England's loveliest towns and picturesque shores. Nostalgia, history, charm and romance are the hallmarks of this brilliantly bedecked rustic Acadia. Rugged shorelines offer visitors a bounty of delicious delights against a backdrop of wistful scenes from fishing harbors to iconic lighthouses. Great cities from Montréal to Québec City offer a French savoir faire, while Savannah and Charleston charm with genuine Southern hospitality.
Contact a Regent Seven Seas Cruises specialist
For detailed information regarding a Regent Seven Seas Cruises itinerary and pricing, please contact our Personal Vacation Planners today!
You may also e-mail us through our online contact form »


text:
These items are available as add-ons to your Invitation order.
These swatches are the available color choices for the designs. If you want a custom color that is not in these swatches, we can do that, using CMYK values for an additional fee of $15. Contact us for this option. Click here to view our Color Swatches.
*Due to the fact that products are printed on different presses and sometimes on different print runs, ink colors may vary slightly
These swatches are the available cardstock and envelope colors we carry. If there is a certain color you are looking for, contact us at firstname.lastname@example.com for this option. Click here to view our Cardstock/Envelope Swatches.
Click here to view Ribbon Color Swatch


text:
Studio Stool
Overall Dimensions: 15.25"W x 15.25"D x 18.5"-23.5"H
Seat Diameter:12.75"
Adjustable Seat Height from 18.5"-23.5" High
Five Star Chrome Base with 2" Covered Casters
Pneumatic Gas Lift
Chrome Foot Ring
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