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|Exam Code
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Accueil du site > Congrès-Séminaires > Archives > Séminaires 2017-2018 > Séminaire du Jeudi 5 avril 2018
Anne-Lise Maire (MPIA Heidelberg)
Thursday April 5th - 11am
IPAG Seminar Room - IPAG
Astrometric monitoring of directly imaged exoplanets and brown dwarfs allows the study of their orbital parameters and system architectures. Because of the long orbital periods and/or faintness of these objects, accurate astrometry is challenging when based on data acquired on timescales of a few years. The new high-contrast imaging instrument VLT/SPHERE provides exquisite contrasts and astrometric accuracies down to about 1 mas thanks to its dedicated design and the use of optimized observational strategy. We will present the results of the astrometric monitorings of the brown dwarf HR2562 B and giant exoplanet 51 Eridani b monitored as part of the SPHERE consortium exoplanet imaging survey.
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How to Answer Awkward Questions About Your Autism
Explore this Article Handling Questions Well Scripting Useful Responses Questions & Answers Related Articles References
wikiHow is a "wiki," similar to Wikipedia, which means that many of our articles are co-written by multiple authors. To create this article, volunteer authors worked to edit and improve it over time. This article has also been viewed 15,341 times. Learn more...
Autism can be a confusing subject for non-autistic people, and when you decide to share the news, they may put their feet squarely into their mouths. It's rarely personal, but it can be frustrating, perplexing, or even insulting. Here is how to respond with grace.
Handling Questions Well
1Take a deep breath. It is normal to pause in conversation, especially if you need a moment to collect your thoughts. There is no pressure to answer right away.
2Assume the best. Most people who ask awkward questions do not mean to confuse or upset you: they genuinely do not understand autism, manners, or both. If what they said was insulting, they may not have realized it.
- A well-meaning person will use a casual or inquisitive tone, and wait patiently for a response. They will act normal because they don't know it's awkward.
- Sometimes it takes a moment for them to realize this is awkward. If this is the case, they might blush, grimace, smile, fidget, or avoid eye contact. (Many non-autistic people show embarrassment this way.)
- A mean person will use a patronizing or sarcastic-sounding tone of voice. They might tilt their head back to look down at you. You might feel belittled.
3Decide what sort of response you want to give. This depends on both your own preferences and the type of question it was.
- An honest answer always works (whether it's an infodump or an "I don't want to talk about it.")
- A joke might work for a loved one you like to joke with. It can also defuse serious rudeness.
- A sarcastic response can work for people who are being rude on purpose, or who don't care if they're rude. (Be aware that some people don't understand sarcasm.)
4Decline to answer any question if you don't know how to answer, or if you plain don't want to answer the question at that particular time. State that you'd rather not say, and refocus the conversation. Most people will realize their comment was unwanted, and will move on.
- "I'm not sure how to answer that."
- "That's an odd question. Anyhow, a corner seat would help me focus."
- "I'd rather not talk about that. Did you see the Packer game?"
5Don't worry too much about it. You are not burdened with the responsibility of teaching everyone about autism. If someone is mean, or you fumble, or they just don't get it, it's okay.
- If you worry a lot about it, consider getting screened for anxiety or telling a therapist. Many autistic people experience heightened anxiety levels ranging from mild to severe.
Scripting Useful Responses
Answering awkward questions is always difficult. When you're autistic and may have trouble with processing speech, generating spontaneous speech, or being put on the spot, it can be even more difficult. These scripts may help you.
1Handle assumptions about functioning labels with grace. Despite the negative implications, most people who use functioning labels truly don't understand that they can hurt.
- "Yes, some days I am high-functioning. And you?"
- "Actually, I don't like to label myself like that."
2Handle comments that you "don't look very autistic" with care. Sometimes this is said because the person is confused. If it is intended as a compliment, then it comes at the expense of other autistic people, so you might feel insulted on behalf of your peers. Keep in mind that even though it is very rude, the person probably doesn't mean any harm, so a calm dismissal or redirection is usually best.
- "Well, I'm an autistic person, so this is what an autistic person looks like."
- "Yes, I like to confuse my prey that way." (joke)
- "Actually, science shows that autistic people tend to have bigger eyes, shorter noses, bigger foreheads, and basically super cute faces![1] I like to think that I look very autistic." (lighthearted)
3Challenge or refute pitying questions or remarks. Some people do not know how to respond to your autism, and may think that they are supposed to feel sorry for you. You can gently remind them that you're an ordinary human being, or directly challenge their assumptions if you think they can handle it.
- "What do you mean? Why do you feel the need to be sorry?"
- "It's really not that bad. I get up, eat cereal for breakfast, and drive to work just like everyone else."
- "Everyone has challenges. Other people have bad parents, low incomes, or difficult relationships. I have sensory issues and executive dysfunction."
- "Well, the social difficulties can be rough. But I do have a good mind for patterns and computer code, and that's pretty cool."
4Be patient with mentions of brothers, nieces, best-friend's-cousin's-nephews, and other autistic children. When they hear that someone is autistic, non-autistic people frequently like to mention their autistic relatives. Usually they are just trying to establish common ground. You might acknowledge it and move on, or talk with them about their relative.
- "Oh, good for you."
- "Oh, really? I have a non-autistic nephew." (lighthearted)
- "Sixteen? That can be a difficult age. Has she found the autistic community yet?"
5Laugh off comparisons to other autistic people, whether they are famous adults or random children. If a person uses this, they are simply showing that they don't know much about autism, and this is their only frame of reference.
- "Like Temple Grandin? Well, I can't say I like the smell of cows..." (lighthearted)
- "Autistic people are very diverse. Some of us are like Rain Man, and many of us are not."
- "Yeah, I've seen the Big Bang Theory. Amy is the absolute best! She's so clever and funny and... (etc.)"
- "Well, of course I don't seem like those autistic children. I'm an autistic adult."
6Put yourself in their shoes to help you challenge their misconceptions about cures. If they talk about a cure, and how they support it, consider the fact that they don't fully understand how it impacts autistic people. They may be misinformed by Autism Speaks or groups similar to it.
- "Why would I need a cure? I would be a completely different person!"
- "A cure would be like resetting a robot back to factory mode!" (lighthearted)
- "(If they insist.)" "Please do your research on the topic, and understand what the cure actually is. I feel very upset with the conversation."
7Keep your cool if Autism Speaks is mentioned. If you (like many people) disagree with how it's run, it may be very upsetting to you, but it is unlikely that the person has deeply considered what the group actually supports. You may not want to ruin your day thinking about it, so you can give a quick answer and change the subject.
- "Actually, Autism Speaks is really mean to autistic people, so I'm not a fan."
- "Please don't light it up blue; that's run by a group many autistic people don't feel supports them. Would you like to participate in #RedInstead?"
- "Ugh, that organization is really gross. So tell me about your new puppy!"
- If they try to turn the conversation back to Autism Speaks, you can suggest they look it up, or change the topic again. They will get the message.
8Assume ignorance before malice if they use the r-word. Some people genuinely do not realize how much that word can hurt disabled people. A quick, one-sentence explanation is enough to make most people realize that this word is not appropriate, and they will stop using it.
- "That's actually a really hurtful word. Please don't say that."
- "Please don't use the r word. It's very derogatory towards disabled people."
- (if they press harder) "Wait, I'm confused. You want to use a word that is derogatory towards people with disabilities?"
- "(If they call you one)" "Excuse me? Why would you "want" to call me a derogatory word?"
- If someone insists upon using the word after you explain it, then they are probably not a nice person. You are well within your rights to avoid them.
9Reassure someone who is getting embarrassed. Non-disabled people may feel uncomfortable around the idea of disability, so it can be helpful to make them more at ease.
- "It's okay. It's not a big deal."
- "Autism isn't as bad as a lot of people think it is. There's no need to tiptoe around the subject."
- "Don't worry about it."
- "For me, autism is just a fact of life. I'm used to it."
Community Q&A
QuestionWhat will I do if they don't believe me?Community AnswerShrug it off and use a script similar to the responses for "you don't look autistic." For example, "Well, this is what an autistic person looks like." If they refuse to believe you, it means that they value their preconceptions over your real-life experiences, so don't share your secrets or deep feelings with them. Their reaction says a lot about how closely you can trust them. If they are in charge of getting you accommodations, ask what sort of documentation they need to prove that you are indeed disabled.
QuestionWhat should I do when people comment about how autistic I seem?Community AnswerIf you're curious about why they think that, you can ask, "Why do you say that?" Or for an easy response, just smile and say, "Thanks!"
QuestionMy brother refuses to stop saying the r-word. I've told him several times that it's rude, but he just laughs it off and jokes about me getting offended. How do I get it to sink in?AdelaideCommunity AnswerTell your brother that saying the "r-word" is not something to joke about. If you haven't already, tell him why it's rude - it's an offensive slur that people use to make fun of differently-abled people. Make sure you stress the seriousness of this situation, and tell him that it's dismissive and insensitive of him to laugh at you. If all else fails, get your parents involved.
QuestionWhat kind of questions about being autistic would be considered "awkward"?Community AnswerIt's hard to say, because no two people with autism are alike. As a general rule, don't ask someone a question you would not feel comfortable answering yourself, and if all else fails, ask them if they feel awkward or uncomfortable about the conversation you're having.
QuestionWhat is the "r-word" mentioned?Community AnswerThe "r-word" mentioned is "retard" or "retarded" and it is an offensive slang term for someone with intellectual disabilities/differences.
QuestionAny tips on how to tell people if I'm self-diagnosed? I'm afraid of people not believing me for this reason.Community AnswerTry phrasing it in indefinite terms, like "I'm most likely autistic" or "I'm pretty sure I'm on the autism spectrum." Most people will take your word for it, and consider it likely that you're autistic. Unfortunately, despite the fact that many autistic people don't have access to diagnostic resources, many people don't understand why someone might self-diagnose. Seek a professional diagnosis if you can. If you can't, then just stick with telling people that you're "probably" autistic (even if it's pretty obvious that you are). And remember that you're welcome in the Autistic community, diagnosis or not.
QuestionI'm openly autistic, but I keep getting asked if there is a cure, which I find offensive. How do I cope with this?SharkGurrrlCommunity AnswerYou should kindly tell them no and explain the treatment process. If they ask, they probably are clueless about Autism and just care about you and want to know more about it to understand you better. The best way to cope would be to accept this fact. Not everyone is going to understand every problem, and there will be people who ask this now and then. Just tell yourself not to take it so harshly.
QuestionHow do I chew on the chewy without being weird?Yasmine OzhatayCommunity AnswerDon't worry about it being weird! It's completely okay to stim in public, and if someone asks you about it, just explain.
QuestionWhat is Autism Speaks?Community AnswerAutism Speaks is an extremely controversial anti-autism organization that focuses on prevention. Its ads often demonize and dehumanize autistic children, claiming that they ruin the lives of their families. This isn't true, and is deeply hurtful to autistics and their loved ones. It has also come under fire for spending very little money on helping families, working to exclude autistic adults from the conversation on autism, supporting dangerous ideas (like the myth that vaccines cause autism) and therapies, and having ties to white supremacist organizations.
QuestionI'm autistic, and I said I'm r*tarded because I think it's a funny word. Is there something wrong with me if I do that?Luna RoseTop AnswererSometimes, making self-deprecating jokes can be a sign that you don't like yourself, or that you're afraid of the people around you. Could that be true of you? Take some time to examine why you said that, and how things make you feel. Do you feel like you have to demean yourself around other people or feel insecure about being autistic? This may take some time to unpack, and it could be an uncomfortable process (so don't rush it). If you won't be kind to yourself for your own sake, consider this: people with disabilities could hear you, and you don't want to make them feel isolated or bad about themselves. Be the type of person you wish you had supporting you.
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- When in doubt, assume that they mean well, and choose an honest answer over a more sarcastic one.
- If someone is dismissive, cruel, or continuously rude, you might want to consider whether you want to be friends with them. You do not have to hang out with someone who doesn't treat you well or respect your disability.
- If someone hurts your feelings use "I" language to explain why.
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Categories: Autism Spectrum | Answering Questions
Thanks to all authors for creating a page that has been read 15,341 times.
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Plan A Perfect Halloween Hangout With No Financial Stress
What is your plan for the All Hallows' Day?
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Funding Beyond Employment Status
Life should not stop because someone has no job. It is the case with the festivals too. You are unemployed, no worries, sooner or later a job is destined to come, and how long one can stay like this. Everyone try hard for that, but by the time you get a job, nothing should stop you from celebrating life. The guaranteed loans for unemployed can make you feel privileged even in your bad days. But, just make sure that your most recent financial status is good enough to prove you creditworthy. The salary slips from the last employer plays a key role here. Make sure you mention it, or attach it with the basic financial details the lender asks when you apply for a loan online.
Why to wait more? Hurry up and get the loan, when it is about happy moments of life, you should not be a latecomer. Enjoy and drown in the Halloween celebration…


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Friday, November 18, 2016
5 Things That Keep Me Sane At The Airport
8 comments:
Great idea for a post, I love finding a little nook in the airport if I can and curling up with my headphones in and browsing the Internet or reading a good book! I hope you have a spectacular weekend!ReplyDelete
6 times a YEAR? I would consider that a lot too! I fly about twice a year- roundtrip vacation. But I agree- these are my go-to's as well!ReplyDelete
Charging stations are definitely a life saver at airports! I usually don't bother with headphones because I like to people watch as I read a magazine. I never buy magazines except for airports!ReplyDelete
Yes to all of these things! Books are a big one for sure. :)ReplyDelete
Good post. Here are a couple of ideas: instead of using a charging station, buy a rechargeable power bank like the ones by EasyAcc for charging your phone and all your electronics except your laptop. For that, they sell batteries that will power the box for four hours or more. After seeing an episode of CSI: Cyber where charging stations were used to infect phones with viruses, I'm leery of them. Not sure if you have a Kindle, but it cuts down the weight you have to carry, although it doesn't do much good if you have a lot of books or borrow them from the library (unless your library has a way to lend e-books). And, your smartphone (assuming you have one, which I'm certain you do) probably can be turned into a wi-fi hotspot for those times when the airport either doesn't have wi-fi or it costs an arm and a leg to use. Noise-canceling headphones are nice, too... Enjoy your trip and be safe!ReplyDeleteReplies
Thank you! I don't have a Kindle. I am very pro-real books. I've never been a fan of e-reading. Even in college I printed multi-page articles out because I didn't like reading them online. I do have a portable charger for my phone that I also bring along.Delete
As long as I have my kindle and an outlet for my phone, I'm good to go!!! Great post!ReplyDelete


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|July 19th, 2005
Topic: 2nd largest armor battle........
|July 21st, 2005
I believe I found what I was looking for, the battle for the golan heights, at the onset of the syrian advance, they had 1500 tanks...2 tank divisions and 3 tank brigades, the defending israeli's had 170 tanks between 2 tank bridages. In one action, 100 tanks of the Israeli 7th armored brigade was able to hold off and eventually destroy over 500 syrian tanks, here's the lazy mans copy and paste.......
In the northern sector, the 7th Brigade, under the command of Col. Avigdor Ben-Gal, was holding the attack between Masada and Kuneitra, starting off with a force of some 100 tanks. They faced the Syrian 7th Infantry Division with support from parts of the 3rd Armored Division, a force numbering approximately 500 tanks in addition to other armored vehicles. By the afternoon of Tuesday, October 9, Syrian tanks had broken through the Israeli lines and each Israeli tank was desperately defending itself. Things were completely disorganized; the 7th Brigade was separated in the midst of the oncoming Syrian forces. In the meantime, battalion commander Lieut.-Col. Yossi was rushing back to Israel from his honeymoon. On the same Tuesday afternoon, he organized a battalion of his own from 13 damaged tanks and moved up to the 7th Brigade's northern sector. The remaining forces of the 7th Brigade were about to withdraw. When Yossi's makeshift battalion arrived, the seven remaining tanks of the 7th Brigade joined his force and moved immediately to a counterattack against the Syrians. They counterattacked in the region near Tel Ahmar that became known as the "Valley of Tears," so named for the amount of destruction that occurred there. The Syrians, who had lost approximately 500 tanks and armored vehicles, withdrew at the attack of Yossi's force. They retreated before the 7th Brigade, which followed the Syrian forces all the way back to the "Purple Line."
Quite an anchievment in my opinion, outnumbered 5-1 and had the courage to launch a counter attack with 20 tanks.
|July 26th, 2005
When Britain attacked at El Alamein there were huge tank assaults on the German lines, some units lost up to 80% of their tanks. Many of them were later recovered as the battle passed them by. Germany at this time lost nearly all of it's tanks, from what I can remember they had just 50 left.


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A Regency so called 'bugbear' coconut cup
Inscribed 'JOHN POLSON SERJANT, 21 ROYAL SCOTCH FUSILIERS', further decorated with various symbols including a mermaid, a hunter, a figure on horseback, fish, a goose, a beehive, Noah's Ark, and sun and moon motifs -- 5in. (12.5 cm) high; 4.1/4in. (11 cm) diameter.
Comparative literature: Edward H. Pinto, Treen and Other Wooden BygonesG. Bell & Sons Ltd 1969. Comparables illustrated, pp. 194, see pl. 203 & 204,
Condition: Excellent condition.


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Out of it's initial statement throughout 1972 some people possess prevailed making use of their reactions to excess fat plus cardiovascular health problems a result of Atkins Diet regime. When unveiled by way of Medical professional. Atkins, the particular strategy can be just as powerful throughout taking care of numerous ailments like cephalalgia, diabetes, apathetic fat burning capacity, trouble that will put up with a number of ingredients, hypersensitivity, plus extra problems. While the reason exactly why individuals decide on Atkins Diet regime is merely who's delivers quick fat loss, some people using huge cholesterol, hypertension, diabetes plus polycystic ovarian symptoms noted make sensed much more dynamic as compared with these people acquired throughout ages right after 7 days about the Atkins Diet regime.
While health and fitness specialists was counseling ingredients very low throughout fats plus huge throughout sugar, the particular Atkins diet regime claims this purchasing need to realize fat loss ought of do the particular opposite. The particular process belonging to the Atkins diet regime would be to receive concerning sixty-six % of this intake of food out of fatty acids and take in various meats plus cheese rather then bakery, pasta, profits, plus vegetables and fruits. Rather then carb plus sweets, the particular Atkins Diet regime very advises fats plus protein. This course evidently contributes to pet proteins; consequently as a result, this will never be quite simple pertaining to vegans.
Lots of nutritionists plus professional medical specialists possess coldly objected Atkins' viewpoint in shedding pounds, seeing that these people reckon that eating limitless amounts with fats, particularly condensed fats throughout various meats goods, might magnify the possibilities of having heart problems.
It is claimed which a diet regime this limits sugar plus brings about our body that will count on it's retail store with fats or maybe lean muscle pertaining to electricity is often most likely risky. While your body stops working stashed fats to produce electricity, your by-product known as ketones can be made. Ketones hold back desire for food, however additionally induce exhaustion, nausea or vomiting, including a most likely risky h2o impairment. Anyone who's body sweets, cardiovascular, or maybe kidney problems need to seek advice from the medical professional prior to commencing every diet regime that is definitely very low throughout sugar.
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Install Oracle Database on a server by using Oracle Database Installation Guide for Linux x86-64.
Use Oracle Database Client Installation Guide for Linux x86-64 to install Oracle Database Client on each client node.
If you have many client nodes, consider staging the software centrally, mapping the drive, and running Oracle Universal Installer in noninteractive mode.
If the client nodes only require a default installation into a new Oracle home directory, consider using Oracle Database Quick Installation Guide for Linux x86-64.
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I have this
var num:Number; in Scene 1. I want to use it in the Scene 2 but I have no idea how to do it.
Sorry I am a newb and I have no idea how to look at the documentation corrrectly.
Please help.
One of the possible solutions would be to declare a class that would contain a static variable.
public class StaticVars {
public static var num:Number=0;
public function StaticVars() {}
Then you address it from anywhere using
StaticVars.num. You can fit as many variables in a single class like this as you need to.


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The Revolution in Radiography
Today, digital radiography is becoming more and more prevalent. With digital radiography the x-ray images (radiographs) are available in digital form to aid diagnostics just a few seconds after the images are made. Repeated image taking, and thus additional exposure to x-rays can be avoided as the images may be reworked using digital techniques. Furthermore, the radiographs no longer get lost. Depending on the digital radiography equipment, it is often the case that less radiation is necessary to produce an image. In this way the patient is subject to a much reduced dosage.
With the assistance of digital volume tomography (DVT) the mouth, jaw and facial region can be realistically modeled. This procedure is the basis for rapid and gentle diagnostics in modern dentistry. In this way, the necessary diagnostic security for a complete and successful treatment can be assured.
For example, all the different x-rays necessary for orthodontic corrections can be produced in our practice. Inconvenient referrals are not required.
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These paintings and the accompanying essay come from three years of thinking, three years of thought. Over three years I have noticed how much thinking is a part of my painting. Often I have spent more time sitting and looking and thinking than making marks. I began investigating the angst that I saw entering into the work; failure, weakness, a disquiet, but also a sense of power and playfulness in the failing. I related this to the disintegration I was seeing around me in many of our social structures and I made my focus the questioning of the causes and effects of those failures. I found three constants in my patterns of thought. Those constants are voices of contemporary society such as Hip-hop culture, the legacy of myth, and the power of the act of storytelling. This questioning lead me to wonder if there was a loss of our soul as a society and how as a people we can work to find ourselves again. So I looked back to my own history and memories of where I came from to help guide me.
The paintings focus on what it means to lose the soul. The jump into the unknown. The sadness, the intensity of that loss, the fear of not knowing where we are or how to go on, but also the curiosity in not knowing what is to come and the power in the knowledge that we can determine that; we can forge our own futures.


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The results were boosted by the release of 33 new handsets from a variety of Symbian licenses including the Motorola Z8, Nokia 6110 Navigator and Nokia 5700 XpressMusic.
Symbian also revealed that it has now sold 145 million cumulative smartphone units worldwide.
Symbian CEO Nigel Clifford said: We feel that the rise in popularity of smartphones, the proliferation of affordable high-speed data networks, and the innovation which companies are showing on open mobile platforms should see us extending our 14 quarters of growth into the future.
'We are in the right market at the right time with the right product.


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Having your vehicle get towed without your insight can be unfathomably enraging. Regardless of whether it was a direct result of a misstep you made, as not seeing a sign that says: "No Vehicles After 7:00 PM" or in light of the fact that you deliberately left wrongfully or without paying. By following these tips, you can ensure that you abstain from getting your vehicle towed.
- Check the signs around where you park.
Ensure that wherever you park, you can legitimately do as such. A few regions have certain limitations on things like to what extent you can be stopped there, or at what times you can be stopped. It is likewise vital to be attentive about the kinds of controls that you are stopping by. For example, never park alongside a red control. Different less regular controls that you can't stop at incorporate white checks, which you can just remain at for five minutes to stack and empty travelers. Green checks demonstrate transient stopping, which will mean 10 minutes or less, except if generally expressed. Yellow methods business stacking/emptying as it were. Blue checks are for individuals with handicaps.
- Make sure to pay the meter if there is one.
This is so imperative, don't attempt to dump paying the meters, they are there for a reason: Stopping individuals from stopping without paying. Keep in mind that the fine you will pay for getting your vehicle out of a tow yard or having a boot evacuated will be substantially more costly than simply topping off the meter, regardless of whether you are leaving for a couple of minutes. Nothing is more regrettable than returning to your vehicle to find that it is either gone, or can't be headed out.
- Set a caution on your telephone a couple of minutes before the meter time closes.
It is inconceivably imperative to have a type of alert set with the goal that when it draws near to the time that you need to either leave or refill the meter, you can be there. Set a caution for ten minutes previously, or significantly more in the event that you are a far leave. That way, you will never unintentionally overlook that you must be back at your vehicle, and you won't need to stress over getting your vehicle towed or having a boot be put on it.
- In the event that your vehicle stalls, call your tow organization before another person finds the opportunity.
At the point when your vehicle stalls, make sure that you illuminate your roadside help organization so they can come and tow your vehicle for nothing instead of having it be towed by another person and paying to have it be discharged. Why pay for roadside help and towing in the event that you never use it? A roadside help tow truck can likewise convey you and your vehicle to an auto fix shop rather than just to the tow yard where you may at present be trapped.
While a portion of these tips may appear to be excessively straightforward, they are things that we overlook frequently. Treat stopping simply like experiencing a crossing point, being extremely caution and ensuring that you are free. Make sure to check, and potentially even twofold check to ensure that everything is lawful before you leave your vehicle.


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ISLAMABAD: The voice against conventional politics of Khyber Pakhtunkhwa Chief Minister Pervaiz Khattak is gaining momentum as five rebel Members of National Assembly (MNAs) of Pakistan Tehreek-i-Insaf (PTI) are now joined by eight members of Provincial Assembly.
On Monday evening, these eight MPAs joined hands with rebel MNAs in Islamabad Club in an Iftar party. They discussed various aspects of their movement against conventional politics of KP CM Pervaiz Khattak and future line of action.
Talking to The News, MNA Col (R) Amirullah Marwat said that Pervaiz Khattak is an old politician who is doing conventional politics while PTI is the name of change. "He is serving only four districts of the province, what about other 21 districts?" asked Col (R) Amirullah Marwat.
MNA Engineer Dawar Khan Kundi said, "You see we have been joined by eight MPAs today and many other MNAs and MPAs are in line to join us. All these respectable MPs have rejected the conventional politics of Pervaiz Khattak."
He requested this scribe not to mention the name of these MPAs who have joined them, as this is very preliminary stage and they want to gain more and more momentum. "We discussed various aspects of governance in Khyber Pakhtunkhwa and no one is happy with conventional politics of the chief minister, as all have joined PTI to bring change in the country, but still we see no change in KP," said MNA from Tank Engineer Dawar Khan Kundi.
Col (R) Amirullah Marwat said, "Human beings and animals drink water from same pond of rain water in dozens villages in my district. Keep aside basic health or education facilities, clean drinking water is not available to hundreds and thousands of villages in my constituency, but no one is taking notice of it."
Jobs and posts in different government office are being sold and good positions are being handed over to favourite people. Mentioning story published in daily The News, Col (R) Amirullah Marwat said, "Your newspaper published story a few days back, in which it was clear that appointments made in Ayub Medical Complex Abbottabad were not on merit, and nepotism and corruption was clear in those appointments. So where is the change, which is PTI's slogan?"
MNA Engineer Dawar Khan Kundi said we met Imran Khan and apprised him of what is going on in Khyber Pakhtunkhwa. He appreciated us for keeping up the slogans of the PTI. "We are doing politics not for posts or making money. We just want to serve the masses through PTI's platform which is the only party one can expect change from it, as its leader is selfless and true leader."
He said, "We shall make clear our line of action in coming few days but one thing is crystal clear; we will not allow conventional politics in our province and strive hard to bring change in the province and country.


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Designed by Riccardo Blumer for Alias
Series of stacking wooden chairs and wooden armchairs; available in natural maple, ash-stained ebony, wenge, whitened oak, walnut veneer or matte lacquer. As an alternative, an oak version is available in a variety of colored stains.
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1003 W. Cannon Fort Worth, TX 76104
See the event photo gallery!
Market Day is our Entrepreneurship major's first-semester major project. The students developed a business plan that introduced a problem and a solution that will hopefully end up in a profit for their pop-up shop. Students applied and were given a small business loan for this project. Among the items for sale were:
-Homemade Tamales -Custom designed T-shirts -Chocolate covered strawberry boxes-Festive Chocolate dipped pretzel rods-Chocolate dipped pretzel rods with caramel -Nachos-Pizza-Fuzzy Socks -Spice flavored Gummies-Chimoy Apples-Dessert Shish-Ka-Bobs (Strawberry, Marshmallow, and Brownie)
Thanks to Entrepreneurship teachers O.J. Abanishe and Jayme Rodriguez for such an excellent project!


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Purpose: Zinc metallochaperones (ZMCs) are a new class of anti-cancer drugs that reactivate zinc deficient mutant p53 by raising and buffering intracellular zinc levels sufficiently to restore zinc binding. In vitro pharmacodynamics of ZMCs indicate that p53 mutant activity is ON by 4-6 hours and is OFF by 24. We sought to understand the mechanism of this regulation and to translate these findings pre-clinically. We further sought to innovate the formulation of ZMCs to improve efficacy. Experimental Design: We performed in vitro mechanistic studies to determine the role of cellular zinc homeostatic mechanisms in the transient pharmacodynamics of ZMCs. We conducted pre-clinical pharmacokinetic (PK), pharmacodymanic (PD) and efficacy studies using a genetically engineered murine pancreatic cancer model (KPC) to translate these mechanistic findings and investigate a novel ZMC formulation. Results: In vitro, cellular zinc homeostatic mechanisms that restore zinc to its physiologic levels function as the OFF switch in ZMC pharmacodynamics. In vivo PK studies indicate that ZMCs have a short half life (<30 minutes), which is sufficient to significantly improve survival in mice expressing a zinc deficient allele (p53R172H) while having no effect in mice expressing a non-zinc deficient allele (p53R270H). We synthesized a novel formulation of the drug in complex with zinc and demonstrate this significantly improves survival over ZMC1. Conclusions: Cellular zinc homeostatic mechanisms function as an OFF switch in ZMC pharmacodynamics indicating that a brief period of p53 mutant reactivation is sufficient for on-target efficacy. ZMCs synthesized in complex with zinc are an improved formulation.
- Received March 12, 2018.
- Revision received May 17, 2018.
- Accepted June 4, 2018.
- Copyright ©2018, American Association for Cancer Research.
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First, wearable devices
Studies have shown that the number of people wearing smart watches is growing. Gartner recently reported that global wearable device sales increased by 17% in 2017. The agency predicts that 2020 will be a watershed in the development of the global technology industry. Wearables revenue will surpass the smartphone market, with a scale of $61.7 billion and sales of 477.75 million.
As the name suggests, IoT devices are smart and interconnected. They come in a variety of form factors with optimized connection options and power consumption for specific applications. For healthcare applications, sensors on the wearable device provide information to the cloud platform at predetermined time intervals to analyze and search for anomalous events (eg, hypertension, hypoxia, low/high heart rate, high glucose, etc.). In addition, if a drug is effective, it can provide feedback if the quality of sleep is related to poor vital signs in a region or even signs of an infectious disease.
Although blood testing is always required, as wearable technology becomes more advanced and accurate, more healthcare measurements can be made through this technique and will shift from invasive to non-invasive.
Second, the external sensor
Technology has come a long way. Small wearable devices―such as smart watches, rings, and patches―can be used in low-power modes, and batteries can be used for many years. Many people transmit data over Bluetooth, Wi-Fi, and even cellular mobile networking. This is critical for patients with chronic conditions and poor health, which largely eliminates their potential to return to the hospital. They can now wear sensors at home to monitor their vital signs, even in the presence of abnormal data or Remind the doctor when it causes concern.
Today, wireless sensor systems can collect medical data that has never been acquired before. Sensor data, sensors, microcontrollers, microprocessors, and gateways are further analyzed and sent to the cloud center before being sent to the caregiver. IoT device networks can be directly connected to each other to capture and share important data.
Third, active preventive care
Wearables and sensors allow people to manage their health care and well-being. For patients who are ill or who try to prevent a worsening condition, wearable devices and general external sensors can provide a degree of autonomy while still allowing the doctor to control the actions that need to be taken. Particularly suitable for elderly or demented patients, it also has a GPS that can be pre-set to a safe area and can notify the appropriate party to let them know that the person is at risk.
In addition, data collected from these IoT devices can be used not only by medical service providers, but also by insurance companies, hospitals, fitness centers, etc., to arrive at various conclusions. All of this can be achieved at millions of people in a relatively short period of time at very low cost. But so far, we have to rely on the resulting patient library for research, most of which are done manually.
Traditionally, when people think of family care, they consider blood pressure measurement and diabetes testing. But with the new IoT technology, more and more things can be done at home. Although there are still challenges to overcome (for example, sensors need to transmit data and need nearby hotspots; or if the device is Bluetooth connected, it will need another device, such as a cell phone), but the Internet of Things will still improve the healthcare system. And completely change the way we look at health.


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My heart yearns towards you, and will indulge itself a little, because we are both in the same low place—feeling our vileness, and mourning after our Beloved. Surely there never was such a one as I, so weak and wicked; so willful, not full of His will—but of my own. How I need the emptying from vessel to vessel. I need to have my purposes and enterprises broken that I may learn that His purposes shall stand fast and that He will do all His pleasure. I can say, as the repenting thief did, I am "in the same condemnation," and "indeed justly," receiving but the due reward of my deeds. I have been walking after the sight of my eyes. "The legs of the lame are not equal;" so when we act from sight and sense, our walk is not consistent; it is only when walking by faith that it is so. Vile, ungrateful worm that I am, what has it cost me in bitter anguish; yet the sorrow is nothing to the sin. And, as I said to you, the ill savor will come up continually, until the blessed Comforter brings the savor of rest, even the fragrant sacrifice for sin which was once offered, and which is now pleaded by Him who is the sinner's surety and the sinner's friend. Well, I can only lie at His feet and continue confessing all. I dare not promise to do better; I am in self-despair; but to Him will I look for pardon of the sin, and power against it.
All posts by The Narrator
Ruth Bryan – Letters – 1850-1851 – (1)
The great enemy would suggest that you are too filthy for the fountain, too cold for the fire, too much diseased to appear in the presence of the great Physician. He does this in a wily way, bringing to mind, when you would approach the mercy-seat, some shortcoming or misdoing, in order to turn your eye away from that sprinkled blood which is the sinner's all-prevailing plea. May the Comforter reveal Christ, as He convinces of sin, and take of His precious things–and set them against your vile ones, giving you heavenly skill and understanding to plead–His precious blood against your sin–His perfect obedience against your constant disobedience–His power to heal against your desperate disease.
Robert Murray M'Cheyne – Conversion and Diary 1834
"June 27.— Reading Life of David Brainerd. Most wonderful man! What conflicts, what depressions, desertions, strength, advancement, victories, within thy torn bosom! I cannot express what I think when I think of thee. To-night, more set upon missionary enterprise than ever." "June 28.—Oh for Brainerd's humility and sin-loathing dispositions!" "June 30.—Much carelessness, sin, and sorrow. 'Oh wretched man than I am, who shall deliver me from this body of sin and death?' Enter thou, my soul, into the rock, and hide thee in the dust for fear of the Lord and the glory of his majesty."
B F Morris – CHRISTIAN EDUCATION—ITS IMPORTANCE TO THE CIVIL STATE – 1864
The Christian Life and Character of the Civil Institutions of the United States, Chapter 7
Christian education, from the very beginning of the New England colonies, engaged the attention of the Puritans, and ample provisions were made for the instruction of all the children and youth in every branch of human and divine knowledge. This, indeed, was one object they had in coming to the New World. Cotton Mather, in presenting the considerations for the plantation of the colonies, says :— "The schools of learning and religion are so corrupted as (besides the unsupportable charge of education) most children, even the best and wittiest, and of the fairest hopes, are perverted, corrupted, and utterly overthrown by the multitude of evil examples and licentious behavior in these seminaries."
" The ends," says Cotton Mather, "for which our fathers chiefly erected a college were that scholars might there be educated for the service of Christ and his churches, in the work of the ministry, and that the youth might be seasoned in their tender years with such principles as brought their blessed progenitors into this wilderness. There is no one thing of greater concernment to these churches, in present and after times, then the prosperity of that society. We cannot subsist without a college."
B F Morris – The Mayflower Compact.
The Christian Life and Character of the Civil Institutions of the United States, 1864
"Of the Puritans, it may be said," remarks Judge Story, "with as much truth as of any men that have ever lived, that they acted up to their principles, and followed them out with an unfaltering firmness. They displayed at all times a downright honesty of heart and purpose. In the simplicity of life, in godly sincerity, in temperance, in humility, and in patience, as well as in zeal, they seemed to belong to the apostolical age. Their wisdom, while it looked on this world, reached far beyond it in its aim and objects. They valued earthly pursuits no farther than they were consistent with religion. Amidst the temptations of human grandeur, they stood unmoved, unshaken, unseduced. Their scruples of conscience, if they sometimes betrayed them into difficulties, never betrayed them into voluntary sin.
Ministerial Confessions Oct. 1651 Scotland
Some General Heads of the Causes why the LORD contends with the Land, agreed upon (after seeking of the LORD) by the Commission of the GENERAL ASSEMBLY 1650, with the advice of divers Ministers from several parts of the Kingdom, met at Edinburgh, October 1651, so far as for the present they could attain light therein, which they offer and advise to be made use of by all the LORD's People in the Land, leaving place to add, as the Lord shall make further discoveries hereafter of the guiltiness of the Land, and intending more fully and particularly to enlarge this Paper.
We have not been men of prayer. The spirit of prayer has slumbered among us. The closet has been too little frequented and delighted in. We have allowed business, study or active labor to interfere with our closet hours. A feverish atmosphere has found its way into our closet, disturbing the sweet calm of its blessed solitude. Sleep, company, idle visiting, foolish talking and jesting, idle reading, unprofitable occupations, engross time that might have been redeemed for prayer. Why is there so little concern to get time to pray? Why is there so much speaking, yet so little prayer? Why is there so much running to and fro, yet so little prayer? Why so much bustle and business, yet so little prayer?
B F Morris – The Puritan Settlement in America
Chapter 3 of The Christian Life and Character of the Civil Institutions of the U. S. 1864
The Puritan settlement on the American continent dates from the 22nd of December 1620, one hundred and twenty-eight years after a Christian navigator had greeted the New World with a song of praise, and consecrated it to Christ in prayer.
The Puritan was made of two different men: the one all self-abasement, penitence, gratitude, passion; the other, stern, calm, inflexible, sagacious. He prostrated himself in the dust before his Maker but set his foot on the neck of his king. In his devotional retirement, he prayed with groans and tears; but when he took his seat in the council, or girt on his sword for war, these workings of the soul had left no perceptible trace behind them. The intensity of their feelings on one subject made them tranquil on all others."
This description, in substance, corresponds with what the New England Puritans say of themselves. " We give ourselves," say they, " to the Lord Jesus Christ, and the word of his grace, for the teaching, ruling, and sanctifying of us, in matters of worship and conversation; resolving to cleave unto him alone for life and glory, and to reject all contrary ways,
canons, and constitutions of men in his worship."
B. F. Morris – Christian Life and Character of the Civil Institutions of the U.S. – 1864
Introduction by Byron Sunderland, Chaplain to the United States Senate During the Civil War.
It is sadly true that a very large proportion of the population are strangers to the genuine spirit of the Christian religion, and almost, if not altogether, unacquainted even with the history of its facts and the extent of its influence in the land of our inheritance. The standing complaint of human degeneracy remains against us. Causes have been operating—and of late years with fearful rapidity and strength—to produce a state of moral obliquity and practical atheism among us, appalling in magnitude and of alarming consequence. It has become of late quite customary to sneer at the puritanism of our fathers and to speak with contempt of the severity of their manners and the bigotry of their faith. This impious treatment, by the present corruptors of society, of a generation of men whose lofty principles and illustrious virtues they seem utterly unable to comprehend, is well adapted not only to arouse the deepest indignation but also to excite the most lively concern.
No man can observe the conditions of society in our country, and, the obvious impulses of human conduct, without feeling that the perils against which the fathers warned us, and which have been so faithfully and constantly pointed out by the ministers of religion, have, notwithstanding, increased at a fearful rate, without seeing that the most alarming departures from the standard of individual rectitude and social integrity have occurred among us within the century that is past.
Robert Hawker – A Prop Against All Despair – 1831
"I even I (saith God) am He, which blotteth out thy transgressions for mine own sake, and will not remember thy sins." (Isa. xliii. 25.) " For mine own sake, even for mine own sake will I do it, saith Jehovah. For my name's sake will I defer mine anger, and for my praise will I refrain for thee, that I cut thee not off." (Isa. 48:11, 9.) Do you feel astonished at this? The Lord appears to have expected you should…while we were yet sinners," rebels, and enemies to God by wicked works, " Christ died for us." (Rom. v. 8.) And if the mind stands astonished, as well it may, in the view of such unparalleled mercy, the whole terminates in this reply, "I am God and not man." (Hosea xi. 9.) This answers all objections, and stops every argument, and proves what an apostle hath observed, " That no flesh shall glory in his presence." (1 Cor. i. 29.)
Robert Hawker – 5 Minutes Advise to Prayerless Persons – 1800
It is the aim of this site, Puritan Audiobooks, to give you unique material, not to duplicate other people's work and post it here without their permission. It takes more effort that way, but it is a better contribution to the Christian community.
The almost Christians, like Agrippa, who were just now mentioned, and the half-believers, like Nicodemus, both need nothing more than the frequent recollection of the unpardonable duplicity of an unsettled and wavering conduct; and of the increased condemnation which must finally fall on such in the great day of account. Reader, art thou ashamed of prayer?— ashamed of that which is the distinguishing character of man, and the noblest privilege with which he is furnished? Anticipate, I beseech thee, that hour when the shame will be on the opposite side of the question ; when it will not be the shame of man; of a poor fleeting creature of a day, like thyself; but the shame of an offended God, an injured Redeemer, and the presence of the whole world of congregated beings, at the judgment-seat of Christ!


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Submitted by Kevin Sean Chen on
There are mainly two parts in my presentation this time, results and analysis for the omitted stimulus response (OSR) experiment with spatial stimuli and some preliminary tests for photon counting in retina.
Last time, I talked about a hypothesized simple columnar organization that produces OSR in the retina. We may investigate the circuits by providing light stimuli with spatial patterns. Uniform, checkerboard, and random distributed pixels were used as the periodic stimulus. Fixing the number of flashes, period, and the average brightness, we see that OSR can only be generated under uniform, checkerboard or fixed random pixels (that are unchanged within a trial), but not in the anti-checkerboard or random pixel stimuli (that changes in every flashes). This implies that there may be specific spatial units to produce OSR. Further investigation is needed to identify the size and properties of these units.
In addition, I calculated spatial correlation and temporal information from the spike trains in previous experiments. For spatial correlation, we find that the correlated distance is longer under uniform stimuli than random flickers or checkerboard. Interestingly, those producing OSR seem to also have shorter correlation distance than those that simply response to each light flashes. For temporal information, my extrapolation results seem to provide less entropy rate comparing to the previous researches. I might find another method that fits our experiment better to calculate temporal information. Lastly, I've been reading articles focusing on the strong inhibitions in the retina. The inhibitory signal may not only play an important role in the anti-Hebbian model but also help encoding information through silencing neighbor neurons. Since we've been recently discussing the strong inhibition right after OSR, I'm also interested in how OSR affects the synergitic codes in retina.
For photon counting on the retina, I briefly went through some classic experiments showing the single photon sensitivity and detection of photon statistics in photoreceptor cells. Most researches focus on the gain control and regulation of threshold in the retina under dim light. In the future, we hope to calculate the correlation between spikes from ganglion cells, which really send information to the brain, to investigate whether photon information could still preserve after processing through the retinal circuits.
cjj replied on Permalink
unit of checker board and random pattern
Thanks for the interesting results. In your OSR for patterned stimulus, how does the size of checker board cells compare with the "pixels" of random pattern? Also, to the size of receptive field or the pitch of MEA?
Kevin Sean Chen replied on Permalink
The diameter of receptive
The diameter of receptive fields in retina are 200-300 micrometers in average according to the references, and the distance between electrodes of our 8X8 MEA is 200 micormeters. For the 'pixels' I mentioned in the slides, their size are identical to the checkerboard cells, which is around 60 microumeters. I'll try to change the size of these pixels in the following experimetns.


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These factors were developed based on an examination of previous cases and rulings that specifically considered whether an individual was an employee or independent contractor. The degree of importance of each factor varies depending on the occupation and environment in which the services were performed. The 20 factors are:
1. Instructions. A worker who must comply with another's instructions about when, where and how to work is ordinarily an employee.
2. Training. If the worker is required to receive training to learn how to do the work, an employment relationship is likely.
3. Integration. The more the worker is integrated into business operations, the more likely the worker is to be an employee.
4. Services rendered personally. If the business requires the worker to provide services personally, an employment relationship is suggested.
5. Hiring, supervising and paying assistants. If the worker is responsible for his or her assistants, this is indicative of independent contractor status.
6. Continuing relationship. A continuing or recurring nature of work suggests employment.
7. Set hours of work. If hours are established by the business, this tends to indicate employment.
8. Full-time required. An independent contractor has more freedom as to when and for whom he or she shall work.
9. Doing work on business premises. If the employer requires this, it suggests control by the employer.
10. Order or sequence set. The more this is controlled for, instead of by, the worker, the more employment is suggested.
11. Reporting. The more the worker must report, the greater the control of those supervising him or her, thus indicating employment.
12. Payment by time, not job. Independent contractors are more often paid by the job.
13. Payment of travel expenses. An employer generally retains the right to regulate the employee's business activities.
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18. Making services available to the public. This indicates the status of an independent contractor who will often perform services for more than one business at a time.
19. Right to discharge. An independent contractor cannot be fired as long as he or she produces a result that meets contract specifications.
20. Right to terminate. If the worker can terminate services without liability, this indicates an employment relationship.
To avoid future problems with the authorities, employers should periodically review the nature of their working relationship with all contractors. These 20 factors should be incorporated in this review in order to ensure that the proper employment status is determined.
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