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Strawberry, rhubarb and custard hand pies
"A cheat's creme patissiere is the perfect foil for tart rhubarb and sweet jammy strawberries" - Phoebe Wood.
Perfect for dessert or afternoon tea, these 30 recipes are easy, creamy and heavenly.
"A cheat's creme patissiere is the perfect foil for tart rhubarb and sweet jammy strawberries" - Phoebe Wood.
I love serving this rich, custard pie with caramelised apples and creme fraiche, says Andy.
As the nights start to cool down, this baked custard will keep you nice and warm.
"During the day, as you wander the maze of little streets that make up the Marrakesh medina, you will wind up in Jemaa El Fna square, and when you do, you'll need a coffee and a pastry. Head around the back of Café de France to Al Jawda, on Rue de la Liberté. It's a sophisticated patisserie, filled with a fabulous array of sweet treats: coconut cookies, macaroons, date-filled makroots and stunning mille-feuille. My version is slightly more modern, flavoured with pomegranate and rosewater, and made with a mascarpone cream instead of custard. This really is a stunning centrepiece for afternoon tea or a swanky dinner party," says John. This recipe is an edited extract from Orange Blossom & Honey by John Gregory-Smith (Simon & Schuster, RRP $39.99). Available in stores now.
There's nothing better than a classic Christmas pudding, and Matt Moran's really takes the cake.
These cookies are the perfect treat to leave for Santa and his reindeer on Christmas Eve.
This aromatic Moroccan pudding is full of flavour and is guaranteed to bring the wow-factor to any meal.
A wonderfully sweet crumble for when you need a little bit of comfort. Remember, don't skimp on the custard.
One of my signature flavour combos is coffee, banana and passionfruit – delish. This is a French-toast-style dish, with the soaking custard flavoured with coffee. I use a decent instant coffee, opting for Prontissimo! from Lavazza, says Darren. This is an edited recipe from Chefs Eat Toasties Too by Darren Purchese (Hardie Grant, RRP $29.99). Available in stores nationally now.
This is my Italian version of 'impossible pie'. The rice falls through the custard while cooking, creating layers of sweetened rice and custard. It's delicious served warm or cold, says our Assistant Food Editor, Sam Coutts.


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CRISPRa and CRISPRi Human Genome-Wide Libraries
The original CRISPR-Cas9 complex enables highly targeted knockout of essentially any gene but variations of the CRISPR system use engineered versions of the deactivated Cas9 (dCas9) protein to either interfere (i.e., repress) or activate gene expression without modifying genomic DNA. These gene-regulating variations of CRISPR use the same basic sgRNA design but target gene promoter regions rather than the coding sequence. The promoter-targeting sgRNA, then, recruits a modified dCas9 protein which either activates or represses gene expression—depending on the dCas9 modification. Cellecta's CRISPRa and CRISPRi Human Genome-Wide sgRNA Libraries have been designed and optimized for pooled activator and repressor genetic screens.
Pooled screens can be run with both the CRISPR-activation (CRISPRa) and CRISPR-interference (CRISPRi) systems. Cellecta's CRISPRa and CRISPRi human genome-wide sgRNA libraries have been designed with the following features to facilitate these screens:
- Single-Module libraries–each expressing ~106,000 sgRNA
- Each library targets almost 19,000 human protein-coding genes
- Each gene is targeted by 5 sgRNAs designed against the promoter region (designs based on Horbeck, et al., eLife 2016;5:e19760 DOI: 10.7554)
- 3,700 non-targeting sgRNA controls
- Convenient quantities provided: 200 ug plasmid; 2 x 10^8 TU and 1 x 10^9 TU packaged viral libraries
- Dual-guide CRISPRa and CRISPRi libraries are also available
Human Genome-Wide CRISPRa sgRNA Library
Selective activation of targeted genes when used in cells expressing dCas9-VPH (or other dCas9-activator variations compatible with spCas9 sgRNA designs)
Human Genome-Wide CRISPRi sgRNA Library
Selective expression inhibition of targeted genes when used in cells expressing dCas9-KRAB (or other deactivated Cas9 repressors compatible with spCas9 sgRNA designs)
Mouse Genome-Wide CRISPRa and CRISPRi libraries are also available.
Ordering information
NOTE: Cellecta offers academic discounts on many of our plasmid and pre-packaged libraries to qualifying academic institutions. Please email email@example.com using your institutional email account, and ask for a quote with the discounted pricing.
Quantity provided in each library: 200 ug plasmid; 2 x 10^8 TU or 1 x 10^9 TU packaged
Human Genome-Wide CRISPRa sgRNA Library (single-guide)
Human Genome-Wide CRISPRa Dual-sgRNA Library (dual-guide)
Human Genome-Wide CRISPRi sgRNA Library (single-guide)
Human Genome-Wide CRISPRi Dual-sgRNA Library (dual-guide)
If you are interested in a custom library, Cellecta can help. Visit our Order page for specific instructions.
User Manual
- CRISPR Pooled Lentiviral sgRNA Libraries (Online Manual or PDF)
Gene Lists
sgRNA Sequences
- Sequences are provided upon shipment of library.
Vector Information
|Single sgRNA Library Vector
|NGS Cassette
|.txt | .gb | .dna
|Dual-sgRNA Library Vector
|NGS Cassette
|.txt | .gb | .dna
Product Certificates
|Lot Number
|Catalog Number
|Product Certificate
|Human Genome-Wide CRISPRi sgRNA Library (virus)
|2 x 108 TU
|Human Genome-Wide CRISPRi sgRNA Library (plasmid)
|200 µg
|Human Genome-Wide CRISPRa sgRNA Library (virus)
|2 x 108 TU
|Human Genome-Wide CRISPRi sgRNA Library (virus)
|2 x 108 TU
|Human Genome-Wide CRISPRa sgRNA Library (plasmid)
|200 µg
Safety Data Sheets (SDS)
Next-Gen Sequencing and Analysis
Cellecta CRISPR sgRNA Libraries are provided with a complete protocol and all sequencing information to enable researchers to perform experiments and extract the data. However, we also provide Next-Gen Sequencing and analysis services for researchers running their own screens with our libraries. Just provide harvested cells or tissue for each time point or treatment condition (one sample), and we'll extract DNA, amplify the sgRNA sequences, perform NGS, and assemble the data with some basic analysis.
You provide Cellecta with frozen cell pellets or tissue after screening…
…and Cellecta does the rest:
- Extracts genomic DNA
- Amplifies sgRNA
- Performs NGS on the Illumina NextSeq or HiSeq
- Enumerates sgRNA counts from raw sequencing data
Please see the Next-Gen Sequencing and Analysis web page for additional information and instructions on how to order.
dCas9 Expression Plasmids
We can also provide other configurations of dCas9 expression plasmids on a custom basis. Please inquire if you require something different than the items described above.

subset: commoncrawl


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Domestic water activator (electricactivator) AP-1 version 3 is an easy, compact device that allows everyone in the home in just 10 minutes to get about 2 liters of activated (with negative ORP "live" ionized and "dead") water. The device is electrically safe, certified. Power consumption is 70W, 220V.
ATTENTION: for US, Canada & Australia networks, need converter adapter 110v to 220v & with plug EU/US or EU/AU - (Not supplied with the device).
Two ceramic glasses are supplied with the device. Cylindrical - volume of 700 ml. And the standard is 300 ml.
The electrodes of the device are made of food grade stainless steel and titanium VT1-0. To protect against the interaction of the anolyte with the electrode material, the anode is further coated with a layer of platinum group metal oxide. The instructions to the instrument warn of the inadmissibility of cleaning the anode mechanically.
Delivery set:
Living water (alkaline, ionized) - pH = 8.0-10.5 units, ORP = - 250 - 400 mV (redox potential, Redox).
Excellent stimulant, tonizer, energy source. It sets the whole organism in motion, gives energy, cheerfulness, stimulates the regeneration of cells, gently raises blood pressure, improves metabolism.
Perfectly heals wounds, ulcers, incl. Stomach and duodenum, bedsores, burns.
Helps in the treatment of prostate adenoma, in the treatment and prevention of atherosclerosis, polyarthritis, osteochondrosis.
Domestic use of living water: accelerates the germination of grain and seeds for planting, stimulates the flowering of domestic flowers, revitalizes green vegetables and wilted flowers, improves the taste of baked goods (when kneading the test on live water), the quality of the syrup for bees feeding (bees become more energetic), stimulates Growth and resistance to diseases of poultry and livestock (the mortality of young animals decreases), watering the beds with live water stimulates the maturation of the crop.
Dead water (acid) - pH = 2.5-5.5 units, ORP = + 500 and more.
Perfect bactericide, disinfector. It is used in the prevention and treatment of colds, flu, angina.
Reduces blood pressure, calms the nervous system, improves sleep.
Helps in the treatment of paradantosis, stops bleeding gums, dissolves the stones on the teeth.
Reduces pain in the joints. Quickly helps with intestinal disorders. Dermatomycosis (fungal diseases of the skin) take place in a few days.
Domestic use of dead water: disinfection of residential and non-residential premises, drinking water, soil, containers, clothing, shoes, removing scale from the walls of dishes, increasing the shelf life of vegetables and fruits, and much more. Normalizes the digestive tract in domestic animals and poultry.
Joint application of live and dead water contributes to the treatment of such diseases as allergy, hepatitis, psoriasis, female diseases (colpitis, cervical erosion) and many others, since the general principle of recovery is the maintenance of the hydrogen index of all body fluids and exhaled air pH 7.1- 7.4, and ORP - in the negative range to reduce the activity of free radicals (Read more in Dina Ashbakh's book "Living and dead water - the newest medicine of our time")
Activated water is used in the household, at home, in the garden and in the garden, for hygienic purposes, in animal husbandry and poultry farming, etc. The effectiveness of the activated water produced by the domestic water activator (electroactivator) AP-1 increases also because during electrolysis "Dead" water acquires a positive, and "live" - a negative electrical potential. It becomes like a weak electrolyte, which quickly interacts with body fluids (gastric juice, blood, lymph, intercellular fluid, etc.).
The human body is an energy system. Long-term practice of using activated water prepared by domestic activator water (electroactivator) AP-1 confirmed the conclusions of scientists that it is the positive and negative charges of this water that are very conducive to maintaining the energy balance of cells.
Worldwide shipping with tracking number - free.
Shipping to the United States & Europe up to 7-9 days, other countries - 10-30 days
+ time of customs clearance and delivery within the country.
Accept only PayPal.


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I will be in San Francisco this Christmas with my family and I need boarding for my little dog from Dec 22 (morning) and December 29. Ranger is a neutered male mini schnauzer, sweet as pie and very needy – he will stick to you like Velcro. He is a house pet and needs to be kept indoors the majority of the time. He needs a loving environment and lots of attention. He does not shed and he is flea-free and up to date on his shots. If anyone would like to take care of him, I will pay $200.00. Must love dogs and have a fenced-in area where he can do his business. Please contact me at 404-488-9882 asap if you are interested.
God bless,
Becky Parton


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Welsh EfW facility underway; Deal for innovative plastic technology; Tyre recycler in UK's top 100 SME exporters; Yorkshire plant blaze
Welsh EfW facility underway
Work has started on the £100m Enviroparks Wales energy-from-waste facility (pictured).
Enviroparks is a Welsh company that has received UK government backing via a £150m, 15-year subsidy to produce green electricity from the advanced thermal treatment of waste.
Dawnus Construction has been contracted to build the facility which will create 200 construction jobs and approximately 200 longer term positions.
Welsh economy Minister Edwina Hart said "I am very pleased to see this project go ahead with Welsh Government support, as it will contribute to our objective for Wales to become a world leader in green energy."
Press release
Deal for innovative plastic technology
Environmental Recycling Technologies (ERT), which holds patent rights for its powder impression moulding (PIM) process, has signed heads of terms with international metals recycler Metallis Recycling to incorporate a joint venture company for the manufacture and sale of PIM flat sheet for the UK market.
The joint venture will initially be owned on a 50% basis by both parties.
Lee Clayton, managing director of ERT, said: "We have been looking for a partner who could take on the manufacture and supply of this sought after product and have actively decided upon a closer participation with our new flagship UK manufacturer so that we can contribute more actively to the business."
Press release
Tyre recycler in UK's top 100 SME exporters
A UK tyre recycling company ranked in the UK's top 100 small and medium enterprises (SMEs) which have grown their exports the fastest over the last two years.
Murfitts Industries been recognised in the 'Sunday Times SME Export Track 100'.
The company manufactures rubber granules for use in artificial sports pitches, children's playgrounds, carpet underlay and modified road asphalt.
It produces the granules from recycled vehicle tyres at its plant in Lakenheath, Suffolk, processing around 11 million car tyres each year.
Press release
Yorkshire recycling plant blaze
Firefighters were called to a recycling plant in Selby, North Yorkshire, after 500 tonnes of shredded material caught fire.
They arrived at the scene at 1.30am and extinguished the blaze with help from another crew sent from Snaith in Humberside.
North Yorkshire Fire & Rescue Service said the cause was believed to be spontaneous combustion.
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Cody and Molly planned their engagement session where they fell in love... Michigan State University. They have deep roots in Spartan football and you can feel their affection for their school immediately. I've done loads of wedding and engagement photography sessions on campus and know the grounds well- I could work blindfolded there. However... since Cody works for football, he had a few awesome ideas that I've never captured and a secret spot with the BEST stadium vantage point. Out of all the sessions I've done there, I've never captured the view of the stadium quite like that! In the end, we were able to pull off a fresh and fun session that felt very distinctly Cody and Molly.
Thanks again to this dynamic duo for the tour of campus... can't wait for next May!! xoxo
Looking Glass Photography is a wedding photography studio offering a blend of photojournalism and styled portraiture. Serving Lansing, Howell, Brighton & willing to travel for Grand Rapids, Detroit & throughout central Michigan.
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XTP Racquet and Paddle Products Presents the XTP Butt Caps
The Newest in racquet customization has arrived.The XTP Xtended Tennis Product lets you easily Xtend the length of ANY racquet or paddle by simply adding our patent design butt cap to your racquet.
Most standard length rackets are 27 inches in length, but MANY manufacturers make what are called Stretch versions and many players prefer these stretch models. Greats that use stretched models include Rafael Nadal, Serena Williams, Juan Martin del Potro, Michael Chang Prince precision 28 inch and Andy Roddick Babolat pure air drive 27.5 inch.
Many racquet manufacturers offer many models in stretch version like Wilson 6.1 pro staff stretch plus and Team 105 XL and Hyper 5.3 27.5 inch. Also Yonnex Pro RD long 27.5 and 28 inch. Prince Graphite Long body racquets are very popular. Babolat makes a full line of Max drive and Aero 112 27.5 long versions. Dunlop iDapt 27.5 Head tennis also makes various lengths longer than standard.XTP can also take a Jr. 26 inch racquet to 26.5
XTP patented butt cap design with pat."HeatFit"Technology allows a very simple way of Xtending ANY racquet.By removing factory butt cap and installing the XTP. You can add normal .5-half inch or by inserting a spacer slightly more. Most players we find only want .5 inch Xtension.
EXtended models increase power and reach of a racquet. So if you have ever wondered what your game would be like playing with a stretch racquet or paddle try the XTP cap. No need to purchase new racquets; simply change the cap and swing away.
These can be purchased online at www.paddles4less.com in most popular sizes. In stock are sizes L0/1, L2, L3, & L4, so please check your racquet size before ordering. We now ship WORLDWIDE with distributors in Australia/New Zealand the U.K. and have bulk pricing for distributers and tennis shops.
For MORE Dealer locations, Click Here
Tested by USRSA.Dealers wanted xtp
Call 8186253634 John R.Keller for more info.


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A Certification Practice Exams Boot camp & Braindump
A certification training is experiencing a great demand within the IT industry. In recent years, the A Certification has become a global standard for many successful IT companies. There has been an increase in the importance of achieving your A Certification today!
Using the virtual A Certification Bootcamp or A Certification Braindumps at Pass4lead.com, no need to purchase anything else or attend expensive training, we promise that you can pass the A Certification exam at the first try , or else give you a FULL REFUND. In addition, Pass4lead.com offers free A Certification practice tests with real questions.
All of our content is custom written and kept current with several monthly updates on most of our products. As a Pass4lead.com A Certification candidate, you will have access to our updates for 90 days after the purchase date.
With our complete A resources , you will minimize your A cost and be ready to pass your A tests on Your First Try, 100% Money Back Guarantee included!
List of Network Appliance NACA Certification Certification Exams
NS0-101 NetApp Accredited Sales Professional Exam 98 Q&As Detail
NS0-102 NetApp(ASAP) Accredited Storage Architect Professional 176 Q&As Detail
NS0-111 Network Appliance Storage Associate Exam 165 Q&As Detail
NS0-120 Data ONTAP Advanced Exam 95 Q&As Detail
NS0-121 Network Appliance Data ONTAP Advanced Exam 7G 128 Q&As Detail
NS0-130 Storage Professional Data Protection Practice Test 48 Q&As Detail
NS0-131 Network Appliance Data Protection Exam 7G 133 Q&As Detail
NS0-141 Network Appliance High Availability Exam 7G 127 Q&As Detail
NS0-145 NetApp Certified Storage Associate 153 Q&As Detail
NS0-151 Network Appliance SAN Exam 7G 127 Q&As Detail
NS0-153 Network Appliance Storege Networking 184 Q&As Detail
NS0-154 Data ONTAP 8.0 7-Mode Administrator 153 Q&As Detail
NS0-163 Network Appliance Data Protection Solutions 183 Q&As Detail
NS0-210 Network Appliance FAS900 Pre-Sales Engineer Exam 125 Q&As Detail
NS0-301 Network Appliance Certified Solution Architect-SAN 80 Q&As Detail
NS0-310 Network Appliance Solution Architect-Backup and Restore 104 Q&As Detail
NS0-320 Network Appliance Solution Architect-Business Continuity 100 Q&As Detail
NS0-AS3 NetApp Accredited Service Engineer Level 3 105 Q&As Detail
NS0-ASE NetApp Accredited Service Engineer Level 2 105 Q&As Detail


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Arkansas Business Entity Name Reservation & Naming Requirements Guide
Suppose 'Andy' wants to start a business in Arkansas. Out of excitement, he starts searching for the perfect business name for his business. And after lots of ideation, he finally selects the perfect name for his business.
He visits the Secretary of State website and starts the business formation process. But his excitement is short lived. Do you know WHY!!!
Because for forming a business, there are a number of documents required to be filled like filing articles of organization, operating agreement etc. And poor 'Andy' does not have the documents ready.
So now what?
Will 'Andy' lose his chosen business name? No! For such scenarios business name reservation comes in handy. All 'Andy' needs to do is file for business name reservation and pay a small amount of $25 to reserve the name.
This protects the business name from being registered by someone for a period of 120 days and by that time 'Andy' can prepare for business formation. Also, the business name reservation can be further renewed and transferred to someone else.
Arkansas Business Entity Naming Requirement for LLCs and Corporations
Arkansas Secretary of State has mandated certain business naming rules and regulations, which every business adhere to. So while choosing the business name, you've to account for these rules.
The business name must be unique and distinguishable from any existing business entity name registered with Secretary of State. Also any difference in grammar, similarly sounding business name, or using stop words does not make the business name unique and it will lead to the name being rejected.
For example, the following names are not distinguishable:
- Justin Plumber LLC vs The Justin Plumber LLC
- Mango Farm LLC vs Mango Farms LLC
- Jake & Mary Corporation vs Jake and Mary Corporation
Required suffix in the business name:
- Language stating or implying the entity is formed for an impermissible purpose.
- Certain words such as college, bank, insurance etc are restricted to use without approval from the concerned board.
How to Check for Business Name Availability in Arkansas
Now that you're aware of the rules and regulations that you must follow while naming the business, let's proceed with the actual name selection.
Arkansas SOS provides an online tool to check for business name availability. You can use this tool to find and research name for your business. We have written an in-depth tutorial on how to use the business name search tool here.
How to File for Business Name Reservation in Arkansas
Business name reservation can be done over Mail or Online. We recommend filing it online as the process is instant.
- Open Arkansas SOS online name reservation page – Link.
- Select filing act as 1003 of 1993.
- Enter the business name you would like to reserve.
- Fill in the contact information and accept the agreement.
- Complete the payment of $22.50.
- The business name you have chosen is successfully reserved.
By Mail
|Download Form
|Secretary of State's Business and Commercial Services Division,
1401 W. Capitol, Suite 250, Little
Rock, Arkansas 72201
|Processing Time
|Around 5 days after the receipt
- Download the name reservation form – Link.
- Fill the form with the requested details.
- Include the money order or check drawn in favor of "Arkansas Secretary of State".
- Send the filled form to:
Secretary of State's Business and Commercial Services Division,
1401 W. Capitol, Suite 250, Little
Rock, Arkansas 72201
For any queries, you can contact the SOS at 501-682-3409 during business hours.
Last Updated: 15/01/2019


text: Recent developments in penile cancer imagingde Vries, Hielke M.a; Brouwer, Oscar R.a; Heijmink, Stijnb; Horenblas, Simona; Vegt, ErikcCurrent Opinion in Urology: March 2019 - Volume 29 - Issue 2 - p 150–155 doi: 10.1097/MOU.0000000000000585 PENILE CANCER: Edited by Philippe E. Spiess and Maarten Albersen Buy Abstract Author InformationAuthors Article MetricsMetrics Purpose of review This review discusses new findings in penile cancer imaging in relation to the European Association of Urology and National Comprehensive Cancer Network guidelines. Recent findings For imaging in penile cancer patients who are candidates for organ-sparing primary treatment, ultrasound with Doppler seems to be the method of choice in addition to physical examination. The sentinel node biopsy (SNB) procedure is used to detect small nodal metastases in clinically node-negative patients. In recent years, this procedure has been enhanced by 3D imaging using single photon emission computed tomography (SPECT) with computed tomography (CT) to improve preoperative localization and interpretation of sentinel nodes, as well as hybrid fluorescent and radioactive tracers to increase intraoperative localization of sentinel nodes. 18F-fluorodeoxyglucose PET (FDG-PET) with CT appears to be mainly useful for pelvic and distant staging in clinically node-positive patients. Other modalities with a potential future role in penile cancer are ultrasound with shear wave elastography, FDG-PET with MRI and ultrasmall paramagnetic iron oxide-enhanced MRI. Summary Imaging modalities in penile cancer have advanced throughout the years, assisting in treatment decision-making and during invasive procedures. aDepartment of Urology bDepartment of Radiology cDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands Correspondence to Erik Vegt, Department of Nuclear Medicine, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands. E-mail: email@example.com Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.


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|credit: google
Arik Air published a new campaign in some national dailies today.
Read the wordings as published:
Arik Air,Naira's biggest fan
At some point in Nigeria's history, the Naira was stronger than the Dollar.
We believe those days can still return, but it can only return when You buy
When you fly Arik Air to London Heathrow, New York JFK orJohannesburg, you pay in Naira and help Nigeria's money stay in Nigeria.
You contribute to making the Naira stronger and a stronger Naira means abetter country for all of us.
• 10 years of Safe and Reliable flying.
• New, state-of-the-art aircraft.
• Fleet maintenance by world renowned Lufthansa Technik, Iberia & SAMCO.
• Only West and Central African airline with a triple IOSA certification.
• Employ over 3,000 Nigerians.
• Unbeatable value and fares to a network of 19 domestic destinations,
10 West and Central Africa destinations and 3 international destinations.
Fly Arik Air. Help rebuild our economy.


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SportsEvents is edited for those who plan tournaments or other sports events.
Issue link: https://sportsevents.epubxp.com/i/1012694
www.sportseventsmagazine.com August 2018 47 t playing fields and beaches. Contact: Cape Cod Chamber of Commerce, www.capecodchamber.org Marlborough With the most concentrated arrange- ment of hotels west of Boston and with Marlborough's restaurants represent- ing the cultural mix of the city, it's geographic location and unrivalled hospitality options make the city a natu- ral magnet for sports enthusiasts from across New England. Hotel rooms: 1,898 Hotel tax rate: 11.7 percent Major facilities: New England Sports Center boasts eight full-size ice rinks and two studio rinks. Fore- Kicks has seven indoor sports fields, two pro basketball courts, two futsal courts, four volleyball courts and two outdoor lighted fields. William Street Baseball Fields is home to three fields. Navin Arena has a full-size hockey rink. Ghiloni Park offers multipurpose space for soccer, baseball, softball, sand volleyball, basketball, skateboarding and track. Convention center: The Royal Plaza Trade Center has 47,500 square feet of space and is attached to a 431-room Best Western. Contact: Visit Marlborough, visit-marlborough.com Merrimack Valley The Greater Merrimack Valley is just a half-hour drive northwest of Boston. The area is known for sports such as skiing, biking and fishing. Hotel rooms: 7,500 Major facilities: Tsongas Center at UMass Lowell is a multipurpose venue with a seating capacity of up to 8,000, depending on event. Lowell Memorial Auditorium can seat 3,000. UMass Lowell Bellegarde Boathouse has ac- cess to the Merrimack River for rowing events. Edward A. Lelacheur Park is located on the banks of the Merrimack River and is home to the New York- Penn League Lowell Spinners, an affiliate of the Boston Red Sox. It is ► M A S S A C H U S E T T S New England Sports Center in Marlborough GAME ON h u n d r e d s o f ve n u e s ye a r - ro u n d eve n t s Find the perfect venue for your next sporting event in Massachusetts. Start planning now at MASportsOffice.com skiing f o ot b a l l ka y a k i n g go l f r u n n i ng ba s e ba l l b m x v ol le y b a l l l ac r o s se c yc l i n g s a i l i ng h o c k ey a r c h e r y y o u n a m e i t. LET'S GO New England Sports Center


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Campers get 'epic' experience at The Ark
The kids camp at The Ark Church in Conroe focused this week on mixing fun with life-changing stories.
With 755 campers and more than 375 volunteers and staff, three daily assemblies, 32 venues, and four water parks, organizers say this week has been truly "epic," falling in line with the name of this year's camp.
"Epic: a story that will change yours" has a classic storybook theme and is based on John 15:5, which the bible's New International Reader's Version states "I am the vine. You are the branches. If you remain joined to me, and I to you, you will bear a lot of fruit. You can't do anything without me."
Campers spent Monday through Thursday jumping in inflatable's, rock wall climbing, zip lining — all mixed with praise and worship.
The children are divided into 32 groups and spend 45 minutes on each activity. The various themes range some of the popular children's tales, like Robin Hood, Aladdin, Sleeping Beauty and Snow White.
Today, the campers will see the final scene of the morning drama they have been watching all week, and even parents get to witness what their children's week has entailed.
"Kids have experienced an amazing week of fun and making new friends while being encouraged to connect to the real God who has good plans for their lives and helps them to grow strong in heart when they stay connected to him," Children's Pastor Dr. Ellen Moore said. "It is truly a life changing week for the kids and the amazing volunteers who so generously give of their time and energy."
Brooklyn Huseman, an 8-year-old student at Wilkinson Elementary, said she enjoys how the camp always provides fun activities for small children.
"They always try to make it fun, like the rides and inflatable's and they act out (drama scenes) on stage," Huseman said. "My favorite venue was the life-size 'Sorry!' board game. We didn't go on this, but there was a coconut tree and you had to try climb it. And I enjoyed the rock wall."
Nathan Riner, an 8-year-old student at Meador Elementary in Willis, said his favorite "true story" from the chapel was Daniel in the lions' den.
He also enjoyed "yard battle," where campers shot rubber balls through a sling shot, and BB gun target shots.
But Riner learned a valuable lesson aside from all the fun and games.
"I learned this week to follow the right path," Riner said.
The camp was funded by a $130 fee for each camper. The church also provided what they called "a wee camp" for the smaller children of volunteers.
The children were also able to win awards for attributes such as character, spirit and the ability to cite bible verses.
In addition, campers raised about $6,500 in four days to provide bibles to children in Ukraine.


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The National FFA Organization, Georgia Association, Jackson Chapter
Hello to all current and future FFA Members!
I am very excited to be at Jackson High School and cannot wait to get the ball rolling on FFA planning for this year!
Your FFA Officers are as followed:
Jillian Rubenstein
Vice President
Reece Rubenstein
Our FFA Meetings will be held on October 2nd in room 311 after school until 4:30pm
Next meeting = November 6th
Looking for students to sign up for the next CDE's. FFA Quiz and Farm Business Management
Looking forward to meeting with you, Your FFA Advisor:
Ms. Brandy Austin
717 Harkness Street, Jackson, GA 30233 |
Phone: (770) 504-2340 | Fax: (770) 504-2341
Copyright © 2019 Jackson High


text: Calculus Early Transcendentals Single Variable Author: Howard Anton Publisher: John Wiley & Sons ISBN: 047064768X Release Date: 2012-06-13 Genre: Mathematics Download Anton, Bivens & Davis latest issue of Calculus Early Transcendentals Single Variable continues to build upon previous editions to fulfill the needs of a changing market by providing flexible solutions to teaching and learning needs of all kinds. The text continues to focus on and incorporate new ideas that have withstood the objective scrutiny of many skilled and thoughtful instructors and their students. This 10th edition retains Anton′s trademark clarity of exposition, sound mathematics, excellent exercises and examples, and appropriate level.


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- Address: 1409 Glenneyre St
- City: Laguna Beach
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Comic book legend Stan Lee has finally been reunited with his mini Pomeranian, Charles. Lee and his friends canvased the neighborhood with "Lost Dog" flyers after the pooch went missing last week but had no luck. It wasn't until NFL great Jim Brown and his wife, who live a mile away from Lee, were out walking that hope was found. After some superhero detective work Brown was finally able to reunite Lee with his Pooch. And it just goes to show that not all superheroes wear capes. Thor ain't got nothing on Jim Brown!
I'm a huge Burt Reynolds fan but Burt is not making it easy to like him these days. Whether he's slapping the press or calling out HIV positive Charlie Sheen for "getting what he deserves", that charming smile and glorious 'stache has seemed to have worn thin over the past few decades. Reynolds was promoting his new movie "The Last Movie Star" when the 82-year old veteran actor took the creep factor to a whole new level. Today's Hoda Kotb asked Reynolds to identify the love of his life to which he responded, with a little hesitation, "Well she was 7 when I met her. She stayed 7 for 11 years… it was Sally Field". Absolutely frightening. He went on to congratulate Hoda for not "making her lips larger" as he kissed her hand, most likely an expression of dislike for plastic surgery even though these days Burt looks like a Ken doll chew toy that a pack of wild dogs share. In his defense he had a very busy schedule that day and the stress probably got the best of him. Hoda at 9am, water aerobics at 10, bingo at 11, lunch and 3 hour nap of course and dinner at 4.
Thought this little tidbit of entertainment news was cool. Remember the TV-loving Mike from Willy Wonka and the Chocolate Factory? Well, nearly 50 years after, Mike's dream finally came true when he appeared as a contestant on Jeopardy recently. 59-year old actor Paris Themmen hid his true identity and credited himself rather as an entrepreneur and avid backpacker, claiming that he has visited over 60 countries. It didn't take fans long to recognize him and the word got out on social media. Themmen came in second with $8,600 in winnings.
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if it does convey to me how to make it happen due to the fact i didn't comprehend nearly anything of those i workout suitable i consider relaxation while you said
Some from admiring admirers who would like to possess a physique as large as Brock's, to those dissing him as a warm-tempered PED consumer.
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Using these achievements and his monster-like built and strength, no wonder individuals have been speculating about his utilization of anabolic steroids. Get lawful steroids online here.
Even Alistair Overeem from the MMA fame has uncertainties regarding how natural his overall body is, stating "I don't see or listen to any of most of these accusations in the direction of Brock Lesnar, nonetheless he is even larger than I am."
Reply Chris Davis Jul 31, 2013 at three:34 pm The main element to carbohydrates about the Rock diet regime is to work with sluggish-burning intricate carbohydrates. George Farah, The Rock's trainer, states that the most effective sluggish-burning sophisticated carbohydrates are sweet or red potatoes, brown rice, and oatmeal. This diet plan has been formulated for what a bodybuilder would do twelve months out from the contest. So, when you wish to be in the top condition of your daily life, persist with People carbohydrates. While in the more time phrase, positive it's okay to take in fruits. You merely don't choose to try to eat them When your aim is To maximise definition for an approaching contest, movie, etcetera.
There are actually pictures of him circulating The web, showing the distinction between how he weighed while he was nevertheless at school in comparison to when he started off wrestling.
Because rep ranges in the 1-5 (where you can't do any more after 5) zone are ideal for energy, doesn't signify it received't assist with dimension, both. You'll get even bigger With this rep vary, and it will be muscle. Just don't overlook to perform cardio.
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A large Portion of why this Motion picture... succeeds... will be the Solid. Owing to Dwayne Johnson, Kevin Hart, Jack Black and Karen Gillan, no matter what reservations there may have been for a film so questionably conceived, are swatted away and roundhouse kicked into your bramble.
Reply Chris Davis Jul twelve, 2013 at eight:00 pm The Rock's coach cautions the Rock exercise routine and eating plan is a thing it is best to get the job done your way as many as. Recall The Rock has actually been teaching really hard for more than 25 a long time at a collegiate/Skilled degree. Current research display that the for a longer period you have got labored out, the more challenging it truly is to overtrain. But, in case you haven't worked out as extended, you'll have to determine according to demo/mistake wherever your Restrict is. Overtraining is quite simple on this work out in the event you're a novice, your variety/respiratory is off, or your not feeding on 7 meals a day (moreover hydrolyzed whey shake).
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Oct 12, 2018
Truck-Trailer Maker Sinks After Warning Tariffs, Labor Costs Will Pound Earnings
Bloomberg News,
(Bloomberg) -- Wabash National Corp., a producer of semi-trailers and truck bodies, plummeted the most since 2010 after saying higher raw-material and labor costs will put third-quarter earnings well below analysts' estimates.
U.S. tariffs on aluminum and steel are driving up the price for many U.S. manufacturers, and Wabash cited "labor instability" that resulted in "higher levels of overtime and lower productivity." A tight freight market has also made it hard for the company's customers to find trucks to pick up Wabash products.
Shares tumbled 22 percent to $13.04 at 11:46 a.m. in New York, after dropping as much as 26 percent, the biggest intraday decline since May 2010. The stock had dropped 23 percent this year before Friday's trading.
Adjusted earning per share for the third quarter are expected to be 27 cents to 30 cents, Wabash said in a statement. Analysts had predicted 52 cents, according to the average of estimates compiled by Bloomberg. Sales are expected to be as much as $555 million, Wabash said, lower than analysts' expectations of $597 million. Wabash said it continues to see "strong overall market demand for our products."
To contact the reporter on this story: Thomas Black in Dallas at email@example.com
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©2018 Bloomberg L.P.


text:
Round second chased still a full
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They appeared to be Cover-3 zone.I appreciate everybody the whole town for backing us and helping us prove others wrong.Carlisle's long-time mantra has been that Phelps could earn $100 million from endorsements during his lifetime – a lofty number for Olympic-based athletes.Republic of Ireland internationals Noel and Stephen Hunt were both ruled out through injury for the hosts, while midfielder Harper was on the bench after a move to Wolves fell through this week.If he loses his job, it would be flat wrongLikely won't run a blazing 40 yard dash.
There are some regions that are weaker general – like Africa or right now, for example – and some teams within stronger regions that 't measure up to the strongest of teams.from the crowd.Hopefully, I'll make the shots." Put a hold on any talk of trying to get to Kidd's level as he again was outclassed their matchup.Nottingham easily beat 3 to make it 14 unbeaten the Championship and move level on points with second-placed West Brom.Statement from : During the closing laps of the NASCAR Sprint Unlimited race, the pace car experienced a fire the trunk area, which contains a purpose-built auxiliary electrical kit to operate the numerous caution lights during the race.
The Bulls impressed from the off front of a vociferous home crowd and deservedly raced into a 10 lead.


text:
A Day Not Forgotten, the Attack on Pearl Harbor
Instructor Amy Ware
October 23, 2010
The attack on Pearl Harbor by the Japanese on December 7, 1941 remains a clear memory for both nations. Everything seemed to have played in favor of the Empire of Japan; from planning, to gathering the necessary resources, the silent 3,300 nautical mile journey of the task force and ultimately the attack itself. From a tactical standpoint the attack was one of the most ingenious naval operations in history. With the loss of four U.S. battleships, 180 Aircraft, and 2,400 sailors the attack can be chalked up as a "win" for Japan. But since the surprise attack was conducted without a formal declaration of war, it may have been …show more content…


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Aldo thousand oaks mall
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Each 2 ounce pack is good for about 2-3 gallons of cider or bottles of wine. Heat on stove top or great to use in a slow cooker—it will make the whole house
smell wonderful!
Hand blended from cinnamon chips, cloves, allspice and star anise.
You'll receive two ounces in a reclosable pack.


text:
Printed: 2019-05-24
View archival description
2010.3.43 - Photograph Negative - Michigan Central passenger train at Niagra Falls
Title and statement of responsibility area
Title proper
Photograph Negative - Michigan Central passenger train at Niagra Falls
General material designation
- Graphic material
Parallel title
Other title information
Title statements of responsibility
Title notes
Level of description
Reference code
Edition area
Edition statement
Edition statement of responsibility
Class of material specific details area
Statement of scale (cartographic)
Statement of projection (cartographic)
Statement of coordinates (cartographic)
Statement of scale (architectural)
Issuing jurisdiction and denomination (philatelic)
Dates of creation area
1965 - 1975 (Creation)
Physical description area
Physical description
Photograph negative showing a Michigan Central passenger train at Niagra Falls. Stored in a small orange envelope.
Photograph measures 5.5 inches width by 4.6 inches length.
Publisher's series area
Title proper of publisher's series
Parallel titles of publisher's series
Other title information of publisher's series
Statement of responsibility relating to publisher's series
Numbering within publisher's series
Note on publisher's series
Archival description area
Custodial history
Copy photograph negative from Palmer's Camera in St. Thomas, which was located at 687 Talbot Street between 1965-1975.
Scope and content
Part of a collection of photographs from the Scott Studio, which purchased Palmer's Camera in 1973 after the death of Mrs. Palmer. This camera shop also had an Aylmer location.
Notes area
Physical condition
In good condition, with a few spots of fading in the top right quadrant of the negative.
Immediate source of acquisition
Donation by Marguerite Sefton
Language of material
Script of material
Location of originals
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Restrictions on access
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Finding aids
Located in archival storage in the men's waiting room of the Canada Southern Railway Station.
Associated / related material
Other notes
Standard number area
Standard number
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Name access points
- Michigan Central Railroad (Subject)
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Catalogued June 17, 2014 by Emileigh van der Maarel.
Language of description
Script of description
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162.9 KiB
July 28, 2014 12:33 PM


text:
- NYT used images of bodies in a story reporting on the 14 Riverside terrorist attack
- The report left Kenyans disappointed who attacked NYT's East Africa incoming boss Kimiko
- Kimiko apologised for the reporting but said she was not involved in selecting pictures for the story
- In a statement NYT said the reporting was within its operating guidelines
- Correspondents in East Africa have condemned the Kenyans' social media attacks
Journalists working for international broadcasters in East Africa have strongly condemned a bruising social media attack unleashed on New York Times's (NYT) incoming East Africa Bureau Chief Kimiko de Freytas-Tamura.
In a separate story, TUKO.co.ke, reported that Kenyans among other nationals took to social media to protest gory images that were published by NYT on Tuesday, January 15.
Send 'NEWS' to 40227 to receive all the important breaking news as it happens
READ ALSO: DusitD2 attack in pictures: The acts of valor and patriotism that helped Kenyans conquer DusitD2 terrorists
READ ALSO: The three special GSU, KDF and DCI forces involved in DusitD2 operation
The article reporting on the 14 Riverside terrorist attack was punctuated by pictures showing bodies of the dead riddled with bullets at the DusitD2 hotel
In a statement Foreign Correspondents Association of East Africa (FCAEA) said criticism against Kimiko was uncalled for as she was not directly involed in selecting and publishing the images.
READ ALSO: DusitD2 attack: Kenyans identify, congratulate GSU officer for his bravery during rescue operations
"The FCAEA condemns the extremely aggressive and personal attacks through social media against Kimiko de Freytas-Tamura of the New York Times for photographs selected not by her, but by her editors in New York, and used alongside her reporting," the statement read.
The scribes insisted that selecting images to use while reporting on terrorism was a very tedious process and citizens need not to turn their rage on them for 'understandable anger and frustrations'.
"The choice of images used in a time of tragedy is a difficult balance and something editors in newspapers, television and on line media constantly battle to get right. Different publications follow different guidelines.
We absolutely defend the rights of readers anywhere to protest what they see as offensive editorial decisions. That is part of an essential conversation. But we are disturbed by the personal attacks on Kimiko and a general stoking of anger against foreign journalists working in Kenya," the scribes stated.
READ ALSO: DusitD2 attack: Death toll rises to 21 as more bodies are recovered
In a viral Twitter trend dubbed #deportkimiko and #SomeoneTellNewYorkTimes, those who reacted demanded Kimiko be barred from working in Kenya.
They also pressed upon the NYT to pull down the photos claiming their reporting seemed to glorify terror attack that claimed lives of at least 21 people.
Tweeps also maintained NYT was aimed at painting Kenya in bad light insisting that they would have never run similar images if the incident happened in US.
READ ALSO: CJ Maraga's condolence message to families of dusitD2 attack victims sets Twitter ablaze Read more:
During the 19-hour siege, a suicide bomber, blew himself up at the premise as his accomplices went on a gun and grenade rampage.
The al-Shabaab militants were later neutralised by a multi-agency security team on the morning of Wednesday, January, 16.
Investigations into the incident were launched and police have since netted at least six suspects, among them a girlfriend to one of the gunmen.
Do you have a hot story or scandal you would like us to publish, please reach us through email@example.com or WhatsApp: 0732482690 and Telegram: Tuko news.
Kenyans Angered by New York Times Coverage of 14 Riverside Attack | Tuko TV.


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By: Mady Dahlstrom, Content Editor for Porch.com
Whether you live in a farmhouse or modern home, decorating for fall means adding cozy blankets, festive wreaths and garlands, and plenty of pumpkins. For those of you who find the fall season frantic and busy with kids heading back to school and the holidays fast approaching, decorating your home may be the last thing on your list.
Get inspired to decorate your home for the fall season by touring these fall homes that go above and beyond to celebrate the season. These fall homes from the Blogger Community at Porch.com show different ways to add some fall spirit to each room, no matter what your budget!
1. Elegant Entrance
From the moment you step into this charming home you're greeted by a rustic fall display. Fill a side table with pumpkins, a plaid scarf, and greenery for a simple, yet elegant entrance.
Check out the rest of this fall home, here.
Image Credit: Maison de Pax
2. Farmhouse Mudroom
This fall farmhouse mudroom is picture perfect with wicker baskets, plush pillows, and piles of pumpkins, apples, and chopped wood. Mixing in natural elements to a room will not only add a fresh look, but make the space feel authentic and warm.
See more of this fresh farmhouse, here.
Image Credit: Everyday Enchanting
3. Simple Shelving
Add a bit of fall to your home by grouping decorative elements onto a shelving unit. This lovely fall display focuses on simplicity and combining unlike objects. Don't be afraid to mix and match shapes, textures, and prints in your fall décor!
Take a look at the rest of this cheerful fall home, here.
Image Credit: The Blissful Bee
4. Colorful Living Room
Soft blues and warm reds are a great color scheme for your fall home. This cottage home's living room is brightened up with pops of blue, gold accents, and fall foliage.
See what other items this cottage used to decorate for fall, here.
Image Credit: The Happy Housie
5. Vintage Breakfast Nook
This fresh and simple breakfast nook proves that sometimes less can be more. A pretty Russian Olive wreath hangs overtop of a large chalkboard for a sophisticated hint of fall.
Tour part one and two of this fall home, here.
Image Credit: The Wood Grain Cottage
6. Framed Fireplace
From mini pumpkins to burlap bunting, there are so many ways to decorate a fireplace for fall. This home takes a unique twist on decorating the fireplace mantel by using golden frames, wreaths, and faux taxidermy for an enchanting, natural display.
See what else this festive fall home has to offer, here.
Image Credit: Craftberry Bush
7. Modern Farmhouse Dining Room
With the fall season comes dinner parties, Thanksgiving, and a lot of entertaining! This fall farmhouse features all items you can DIY for your next event, like pinecone place cards and painted shutters.
Get the full look at this fall modern farmhouse, here.
Image Credit: Bless'er House


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- This event has passed.
St. Patrick's Day Bash!
March 16 @ 11:00 AM - 11:30 PM
It's our favorite holiday of the year, and we can't wait to celebrate with you!
Doors open at 11a.
Live Music starts at Noon!
Abbots Cross from Noon-2p
RichPatrick Trio from 3p-7p
Verdict from 8p-12a
$12 cover gets you in for the whole day!
Enjoy green beer and shot specials!
Special Irish Pub Menu, plus great Crafthouse favorites!
FREE Valet Parking all day!
Get in the spirit with green beads at the door!


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Is it possible with Bonitasoft to let the user define the process step when initiating the process?
1 answer
Processes are by nature deterministic.
I understand from your description that you want the end-user to specify what step to go next during a process execution. If there is a limited number of pre-defined options, it is possible because the process can gather input from the end-user (usually from a form).
An example of your use case would help to provide you with more complete answer.


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Family Cooking Workshops
April 7 - May 27
We are kicking off healthy eating classes again with Chef NagI, again! Come join us on certain Mondays for Family Cooking Workshops. Please see dates below or on the website for exact class dates. Come learn from a trained Chef on how you and your family can increase your healthy eating profile. Each class is limited in size, but no worries if one class fills up, sign up for the next!


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IBC CEO Adam Zarth calls for support of region's economic centre
Within the next six months we will have seen a state election run in March and a federal election likely held sometime around mid-May. Current polling shows tight and unpredictable contests for the helm at both levels of government, and so as a region we need make our priorities clear and consistent.
Investment in infrastructure to better connect the Wollongong local government area is imperative, as we know too well that the city has been left behind while other parts of our region and the state enjoy an unprecedented investment boom.
While the Illawarra is dotted with busy and productive central business districts like Shellharbour, Nowra, Kiama, Bowral and Moss Vale, the infrastructure and capacity of Wollongong supports our entire region.
Continued efforts to revitalise the Wollongong city centre are essential in attracting businesses from outside our region to relocate here, as well as in allowing new start-ups to flourish. Our highly skilled workforce, diverse economy and lower cost base are the other factors that play in our favour.
Advantage Wollongong is a commendable initiative that works to promote these strengths and attract businesses from beyond our regional borders.
The Wollongong CBD is a key business hub for the state, employing over 25,000 people and experiencing 20 percent growth in jobs over the last seven years.
The ongoing revitalisation of Crown Street is important, and we applaud initiatives like Renew Wollongong, which utilises empty office space and encourages creative enterprises to move in, rent free. The resulting increase in activity will benefit existing retailers and businesses, bringing more foot traffic to the area, thereby breathing life into parts of the city centre.
The commercial core has been completely rejuvenated by the development of Wollongong Central, which just this year has welcomed Critinis and mini-golf cocktail bar Holey Moley to an existing mix of thriving outlets.
The Australian Retailers Association and Roy Morgan are predicting Australians to spend more than $51 billion over the Christmas trading period from November 9 to December 24, 2018 – a predicted 3.1 percent growth over 2017 in pre-Christmas sales across NSW.
The Wollongong CBD is a key business hub for the state, employing over 25,000 people and experiencing 20 percent growth in jobs over the last seven years.
We'll be monitoring holiday trading closely, but already see the signs of record Christmas season for our retail sector as we know that consumers still prefer face-to-face service and the ability to see, touch, feel and try.
A lack of quality commercial office space is a challenge for Wollongong. We see a lot of commercial property being retrofitted, but new developments need to be encouraged to provide a greater incentive for the relocation of white collar jobs to our city.
Further afield, the Wollongong local government area is also in need of more commercial and light industrial precincts, and underutilised land owned by BlueScope is viewed as being part of a solution to this. Undoubtedly this area will be of economic benefit into the future.
Similarly the port of Port Kembla will soon become Western Sydney's port and the state's next container terminal. Growth of the port is key to our economic future, and we look forward to exploring how it can support the Aerotropolis at Badgerys Creek through better connectivity in more detail next year.
Wollongong does not receive an appropriate share of the proceeds of the state's commendable asset recycling program, which total $32.9 billion, and the sale of our share in Snowy River Hydro Scheme, which totals $5.754 billion.
We recently outlined our transport priority list for the Illawarra, which contains five key projects that are needed to keep our economy open for business.
Disinclined to make asks of government without a solid evidence base, we can point to the economic benefits in dollars to justify each project.
Other than the Mt Ousley interchange, the F6 Extension is the only other one of the five that has been committed to by the government, and a welcome project so long as stages one, two and three from Arncliffe to Loftus are constructed. The other four projects all begin or end in the Wollongong local government area, and are yet to receive a complete commitment from government, so there is a huge opportunity there.
Regional and rural areas across NSW rely on the road, rail and port infrastructure of Wollongong in order to do business.
Clearly there is much to do in 2019.
Adam Zarth is the Executive Director of the Illawarra Business Chamber
Discuss "OPINION: Support the growth of Wollongong as a regional economic centre"
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Androgen Excess and PCOS Society
Strengthening care for women with Androgen Excess Disorders
About Us
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Ebook Trattato Di Antropologia Del Sacro. Culture E Religioni Indigene In America Centrale E Meridionale 1997
Keep up-to-date with the latest advancements in AMH and Developmental Origins of PCOS.
Attend our Update Meeting during ENDO2018 in Chicago, IL.
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The Androgen Excess and Polycystic Ovary Syndrome Society
is an international organization dedicated to promoting the generation and dissemination of knowledge related to
all aspects of Androgen Excess Disorders.
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Resources for Healthcare Professionals
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Resources for Patients
Polycystic Ovary Syndrome
Learn More
PCOS is the most common androgen-excess disorder, and affects between 5% and 10% of all women. PCOS typically involves the prescence of irregular or absent menstrual periods in combination with excess androgens (male hormones) and possilby polycystic ovaries. Increased production or sensitivity to androgens commonly leads to hirsutism (male-patterned hair growth), acne, or alopecia (thinning or loss of scalp hair).
Congenital Adrenal Hyperplasia
Learn More
Congenital adrenal hyperplasia, also known as CAH, is an inherited disorder affecting the hormones produced and released by the adrenal glands. Approximately 1 in 12,000 infants is affected by CAH. The most common type of CAH is called 21-hydroxylase deficiency which is due to changes in the gene (DNA) that codes for the protein, 21-hydroxylase (CYP21A2).
Premature Adrenarche
Learn More
Premature pubarche is the untimely development of pubic hair and/or axillary (armpit) hair prior to 8 years of age in girls and prior to 9 years of age in boys. The most common cause of premature pubarche is early maturation of the adrenal glands (adrenarche) which results in earlier than normal production and release of androgens, such as dehydroepiandrosterone sulfate (DHEAS).


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If you had to pick one property of a program that makes it easier to maintain, what would it be? Good documentation is certainly a candidate, but if the code itself is bad enough, that probably won't help you. How about encapsulation? It can be liberating to know that the changes you're making to a piece of code will only have local effects. However, what if there are other versions of that same code encapsulated elsewhere? Oops. To my mind, the most important property is lack of redundancy. The more places in the code that perform the same function or embody the same implied understanding, the harder it is to maintain without breaking something. This has been well-understood in the database world for decades; normalization is nearly a religious practice in relational database circles. The principle is important enough that it has a well-known acronym: DRY (Don't Repeat Yourself). How might we apply this principle to Kubernetes manifests?
Kubernetes Redundancy
First of all, is this even a problem for Kubernetes manifests? For a single application, maybe not. The services, deployments, and other Kubernetes constructs will likely all be unique since any common behavior will be supported by replicated pods at runtime, not by replicated controllers in manifests. However… the ease of container-based deployment has made it common practice to run an application in a variety of environments. At Yipee.io, we run our own application in production, staging, and development environments, from public clouds to developer laptops. This ability to easily replicate a significant application is extremely powerful but brings with it the problem of maintaining several closely related but non-identical application configurations.
Existing Approaches
There have already been several attempts to address this problem within the industry. Here are some of the most prominent:
docker-composeprovides the option to use multiple configuration files (for Swarm applications). Each additional configuration file overrides any previous ones for singular values and merges sets of values with those from earlier files.
Helmsupports manifest templates that can be used to parameterize deployments. Sections of a YAML manifest can be marked as variables which are instantiated via separately specified values.
Ksonnetsupports programmatic configuration of Kubernetes apps via code in the extended JSON dialect Jsonnet.
Kustomizehas overlays that can be applied to base YAML manifests to produce specific configurations.
All of these work (with varying levels of convenience and power) but have issues:
docker-compose's multiple configuration files only allow certain values to be changed and only in specific ways.
Helm templates require the base configuration to anticipate what parts might be changed by later overrides so that template variables can be inserted. Also, they require the user to learn an additional templating language in order to construct shared configurations.
Ksonnet uses a unique configuration language based on JSON. This forces users to learn a new formalism and makes configurations opaque for new users.
Kustomize's overlays are just YAML which means users don't have to learn a new language. However, the division of a model into many separate related files makes it hard to figure out just what a model contains and the overlays themselves cannot be read in isolation since they are updates to existing files.
The Yipee Approach
Yipee.io started out as a SaaS-based graphical modeling tool for building Kubernetes manifests and Docker Compose files. It was clear from the start that YAML, though capable of expressing complex configurations, left something to be desired as the sole representation of an application. In particular, though it's relatively easy to modify an existing configuration for someone who knows how the application works, it's difficult to see the big picture when looking at a large configuration in YAML. Yipee.io models, which represent Kubernetes objects graphically, make it far easier to understand the structure of an application. We believe the same holds true for managing multiple related configurations. We're currently building an on-premise version of Yipee.io that runs in a user's own Kubernetes cluster. Models in the on-premise Yipee.io can be derived from "parent" models and inherit their configurations. The derived models can then be modified but maintain their connections to their parents so that parent-level changes can be automatically propagated. The advantages of this approach include:
The model you're working on is always complete. You don't have to piece it together from chunks spread around the filesystem.
Graphical diffs between models (and versions of a single model) make it easy to see how a configuration has changed, even if large-scale changes have been made.
Upstream changes can be accepted/rejected in bulk or they can be addressed on a per-change basis. The system remembers when you change or remove a parent model object and won't ask you to reprocess a change if you compare the same two models again.
Changes to ancestor models don't accidentally break descendant models. Unless a user explicitly accepts upstream changes, the descendant models remain unchanged. If a user does want the changes, though, it's trivial to accept them.
Subsystems can be included or embedded. If the subsystem is best viewed as a black box, it can be treated as if it were itself a Kubernetes object. If it's more naturally seen as a set of top-level parts, it can be unpacked directly into the descendant model.
Contrast two representations of the same application. First, the Kubernetes manifests:
# Generated 2018-08-15T21:33:09.964Z by Yipee.io
# Application: Parse-MongoDB
# Last Modified: 2018-08-15T21:33:09.964Z
apiVersion: v1
kind: Service
name: parse-server
yipee.io.modelId: 7adf4c72-4ca6-11e8-b87b-87cec0af93b2
yipee.io.modelURL: https://staging2.yipee.io/editor/7adf4c72-4ca6-11e8-b87b-87cec0af93b2/fc55cc2c-4251-11e8-b067-4f2de2893da6
yipee.io.contextId: fc55cc2c-4251-11e8-b067-4f2de2893da6
yipee.io.lastModelUpdate: '2018-04-30T18:46:32.106Z'
run: parse-server
- port: 1337
targetPort: 1337
name: parse-server-1337
protocol: TCP
nodePort: 31337
type: NodePort
apiVersion: v1
kind: Service
name: mongo
yipee.io.modelId: 7adf4c72-4ca6-11e8-b87b-87cec0af93b2
yipee.io.modelURL: https://staging2.yipee.io/editor/7adf4c72-4ca6-11e8-b87b-87cec0af93b2/fc55cc2c-4251-11e8-b067-4f2de2893da6
yipee.io.contextId: fc55cc2c-4251-11e8-b067-4f2de2893da6
yipee.io.lastModelUpdate: '2018-04-30T18:46:32.106Z'
app: mongo
- port: 27017
targetPort: 27017
name: peer
protocol: TCP
type: ClusterIP
apiVersion: apps/v1beta1
kind: StatefulSet
name: mongo
yipee.io.lastModelUpdate: '2018-08-15T21:33:09.920Z'
yipee.io.modelId: edb88f9e-641e-11e8-8a4d-f3d7597e94c6
yipee.io.contextId: 89a94702-1558-11e7-a147-df26953bf272
yipee.io.modelURL: https://app.yipee.io/editor/edb88f9e-641e-11e8-8a4d-f3d7597e94c6/89a94702-1558-11e7-a147-df26953bf272
type: RollingUpdate
partition: 0
name: MongoDB
component: mongo
app: mongo
imagePullSecrets: []
- name: init-mongo
image: mongo:3.4.1
- bash
- /config/init.sh
- name: config
mountPath: /config
- name: mongodb
- containerPort: 27017
protocol: TCP
name: web
image: mongo:3.4.1
- mongod
- --replSet
- rs0
- name: config
name: mongo-init
terminationGracePeriodSeconds: 10
name: MongoDB
component: mongo
app: mongo
podManagementPolicy: OrderedReady
replicas: 3
serviceName: mongo
apiVersion: extensions/v1beta1
kind: Deployment
name: parse-server
yipee.io.lastModelUpdate: '2018-08-15T21:33:09.920Z'
yipee.io.modelId: edb88f9e-641e-11e8-8a4d-f3d7597e94c6
yipee.io.contextId: 89a94702-1558-11e7-a147-df26953bf272
yipee.io.modelURL: https://app.yipee.io/editor/edb88f9e-641e-11e8-8a4d-f3d7597e94c6/89a94702-1558-11e7-a147-df26953bf272
name: MongoDB
component: parse-server
run: parse-server
revision: 0
- name: parse-server
- containerPort: 1337
protocol: TCP
name: parse-server
image: parseplatform/parse-server
- name: PARSE_SERVER_APPLICATION_ID
value: my-app-id
- name: PARSE_SERVER_DATABASE_URI
value: mongodb://mongo-0.mongo:27017,mongo-1.mongo:27017,mongo-2.mongo:27017/dev?replicaSet=rs0
- name: PARSE_SERVER_MASTER_KEY
value: my-master-key
restartPolicy: Always
imagePullSecrets: []
name: MongoDB
component: parse-server
run: parse-server
type: RollingUpdate
maxSurge: 1
maxUnavailable: 1
replicas: 1
revisionHistoryLimit: 2
Here's the Yipee.io version:
I think it's clear that the graphical view helps make the big picture evident. You can see instantly that the application is built from three container types, one deployment, one stateful set, and two services. You can also see how they're related. If the structure of the application in an ancestor model changes, a graphical diff will make it obvious what changed and what depends on the change.
The rise of container-based deployment has led many companies to construct multiple variants of their application configurations. These variants have significant commonality and generate the same issues around redundancy that software developers and database administrators have dealt with for decades. The issues are serious enough that, even though Kubernetes is a relatively young technology, multiple players in the industry have attempted to address them with varying levels of success. Yipee.io is developing a graphical approach to managing Kubernetes models that supports embedded models, model inheritance, and model versioning with an intuitive visual editor and graphical diff capability. The graphical diff makes it easy to manage derived models and propagate changes from ancestors to descendants.
If anything you've read here sounds interesting to you, please visit our DRY Kubernetes page and fill out the form to let us know. We're looking for early adopters to help ensure that we're solving everyone's problems and not just our own. Also, if you're a fan of GraphQL, you might want to check out our Kubernetes GraphQL interface that we're building in support of our on-premise product: Kubeiql.
Thanks for reading!


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Discover more informations and stories about this franchise :Boston Market
Macaroni and CheeseFranchise : Boston MarketCategory : Main Dish
3 c Dry spiral shaped pastaCook al dente, drain 2/3 c Milk (2% or regular)1 lb Velveeta cheese, light or- cubed small1/4 ts Dry mustard powder1/2 ts Ground turmericSalt and pepper to tastePlace into top of double boiler over gently simmering water milk, cheese, mustard powderm turmeric, salt and pepper in that order. Stir with whisk occasionally until melted and smooth. Stir pasta into hot cheese mixture and keep hot until serving time over hot water, up to an hour. (If it begins to thicken up too much, dilute with a little milk). Neverput into oven or over direct heat as it will scorch and change the texture to a sticky mess. 6-8 side servings or 4 main-dish servings.Yield: 6 Servings


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He may have been retired, but Stanley Hough still had a few business interests in the Thoroughbred industry. So when his golf game started to slip, and then long-time mentee Hunter Rankin called with a new opportunity, Hough decided to wade back in.
For the past several years, Hough and Sagamore president Rankin have been carefully rebuilding the farm's breeding and racing program, and when it came time for their first 2-year-olds to hit the track last fall, the 71-year-old Hough started to get "the itch" once again.
"I just wanted to see the process through," he explained. "I had gotten pretty good at doing nothing, but then, being around the horses isn't really a job for me."
One of those special young horses was Global Campaign, a half-brother to Grade 1 winner Bolt d'Oro sired by Curlin. A few niggling issues kept him from making his debut until this January, but the colt won both of his first two outings with ease.
Unfortunately, Global Campaign grabbed a quarter in the G2 Fountain of Youth last Saturday but still managed to finish fifth. He is off the Kentucky Derby trail, but Hough is excited for what the rest of the sophomore season will hold for the talented colt.
Also on Saturday, Hough saddled his first graded stakes winner since 2011 when 5-year-old Recruiting Ready won the G3 Gulfstream Park Sprint Stakes by 3 1/4 lengths.
"He's such a neat horse, we just truly love him," said Hough. "We've always felt that he had a lot of ability, and he showed signs of being able to lay off the pace, so he could be ready for a big year."
Talking to Hough about his success is a bit of a challenge because the veteran conditioner of 2,175 winners doesn't like to "toot his own horn," according to Rankin.
"He's been like a second father to me, so it's really special to do this with someone I'm so close to," Rankin said. "He's such a good horseman, so he deserves every bit of the success."
Hough recalls his favorite horses in his first run of training were Proud Appeal and Irish Tower, the former a $37,000 purchase who would go on to win the G1 Blue Grass; Hough sold the colt before he ran in the Kentucky Derby. Irish Tower, meanwhile, won several graded stakes and finished second in the G1 Met Mile.
Other talented horses conditioned by Hough included G1 winning millionaire Request for Parole, G1 winner Spectacular Tide, and multiple graded stakes winners Tar Heel Mom and Meter Maid.
He might not be galloping or even riding the pony anymore, but with 20-year assistant Laz Cruz in the barn Hough is finding his way back to the winner's circle on a regular basis. From just nine starters in 2019, Hough has saddled four winners and three additional on-the-board finishers.
"I'm not really up on the new ideas, but the stuff with the horses, that hasn't really changed," said Hough. "There's no secret – with good care and the right spot, horses tend to run good.
"The horses aren't spread out like they used to be, but there is still room for a good horse. You still can't just buy your way to success."
As for his personal future, Hough isn't sure how long he'll be back in the training game, only that he's enjoying every moment of the Sagamore experience.
"I'd like to finish out this year, and then of course there's always the next crop coming up," he said, trailing off. "Hopefully I'll be training at least another year or two."
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