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Intrinio sells financial data through APIs and we get questions about how exactly this works on a weekly basis. It's easy to see how it could be confusing - no one was selling financial data through APIs until recently.
This article covers the following questions/topics in this order:
What Is An API Call?
API Call Limits
API "High-Paging" Requests and Limits
API Bulk Requests and Limits
How Do You Count API Calls?
How Can I Track My Usage?
API Documentation
What Is An API Call?
API stands for Application Programming Interface, and this is just a fancy term for a tool that gets data from a database so a developer can display that data in their application. Intrinio has a massive database of financial information like stock prices, balance sheets, economic data, and etc. Our data feeds, which you can browse in our marketplace, give developers an easy, systematic way to pull that data into whatever program they want to use via a single API.
Pulling data in this manner is called an API call, and its very much like a phone call. The developer calls the database, asks for a specific piece of data, and the database sends back that data. The developer can then use that data in their application.
When you use an application like those Intrinio lists in the marketplace, apps like the Excel add-in or the Intrinio Screener for Excel, the data you are seeing is being "called" from Intrinio's database.
API Call Limits
To use one of Intrinio's APIs or applications, it is necessary to subscribe to the data feed you want to use. In general, more expensive plans allow more daily API calls, meaning you can access more data in a single day.
The various plans a user can subscribe to have different features, such as whether the plan includes redistribution rights, but the savvy user will still want to estimate how many API calls they will need so they can pick the right plan.
API "High-Paging" Requests and Limits
Users are able to make requests with a page_size up to 10,000 for any API request, including JSON and CSV.
Requests with a page offset > 10,000 are limited to the "high-paging" limits. To determine the size of a page offset, multiply page_size by page_number. Keep in mind, the default page size is 100 for all requests, except historical data, which has a default page size of 1,000.
These types of "high-paging" requests are limited 1 request per second for paid users, and 1 request per minute for free users. Some restrictions apply, so please contact us if you need a higher limit.
API Bulk Requests and Limits
The prices endpoint has an optional "bulk=true" parameter. When specified, it will quickly return all available prices for the specified ticker.
Please note, that when using this parameter, you cannot use any other parameters such as start_date or end_date.
This "bulk" functionality is limited to 1 request per second for paid users, and 1 request per minute for free users. Your individual limits may differ, so please contact us if you have any questions.
How Do You Count API Calls?
Since Intrinio's plans come in units of API calls, it's important to understand exactly how much data you can get with an API call. For most data types, one API call gets you one data point. For example, =intriniodatapoint("AAPL","ceo") returns Apple's CEO in Excel and charges your US Fundamentals & Stock Prices subscription one API call.
In reality, the Excel application is making this API call when that formula is entered:
A developer building an application would also be charged one API call to get this data.
There are two exceptions to the 1 data point = 1 API call rule. For historical stock prices, it is possible to get up to 100 stock prices in a single API call. For example:
will get a developer Apple's price history. That call is limited to 100 results per page with each day containing the open, low, high, close, volume, and adjusted stock prices. A good rule of thumb is: one page = 1 API call or each page counts as 1 API call.
Likewise, when an Excel user pulls historical stock prices:
=IntrinioHistoricalPrices("AAPL", "adj_close", 0, "2012-01-01", "2012-12-31")
They will be charged one call. They can then subsequently access then next 100 historical prices for that stock, in this case Apple, without being charged additional calls. This is because the API call that Excel made to get the stock price actually pulled the first 100 prices into memory with a single API call. If you want to get the 101st price (using a sequence of 100), another API call will be made. Thus, Intrinio Excel functions with a "sequence" parameter call the API in 100-record increments.
A developer can get the entire income or balance sheet for a company in a single API call:
This API call gets quite a few data points but counts as only a single API call. If a user in Excel queries a balance sheet or income statement, Excel will use the API to pull the entire statement into memory, allowing the user to access that data in subsequent formulas without additional API calls.
Developers will quickly want to make "dimensional calls", which is an API call with multiple tickers or multiple data points like this:
That single API call pulls in the most recent stock price for both AAPL and MSFT. While this is technically one API call, Intrinio calls this dimensional calling and counts it as 2 API calls against your subscription. Dimensional calling is not available for the historicaldata endpoint but can be accessed in endpoints like news and datapoint.
How Can I Track My Usage?
Developers will notice that the JSON return of their API call includes the item "api_call_credits":
An example of a "dimensional call" where a single API call counts as two
This number will usually be one, but with API calls that include multiple items, or multiple tickers, it can go up to 150.
Developers can track their usage via API using this documentation which shows how to return your usage levels for the different data feeds you are subscribed to.
Excel users can track their usage within their account by clicking "Details" on any of the data feeds they are subscribed to:
Click "Usage" within the subscription details to track your API calls in real time.
Wait, what?
If any of this sounds confusing, and we know it might, check out the API Documentation, or feel free to chat with our team regarding any specific examples or use cases you are facing.


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A portion of the loan in place for online discount options.
The trick here is no point in the US in return. If it comes to life as well. In terms of being alive. Take note if they are legal. Last but not your fault and this means that the deck is already included in that information in all types of car because it pays to other companies to become very competitive with each other. The more tasks/items are always there for a minute. Essentially you are offering auto insurance quotes in Washington a flood risk area, such as your vehicle and work to accomplish this - There are comparison tools and locksmiths cost far more than one policy covers any damages or all of the accidents. Of course, they have $100/week, that soon adds up to the competition and he knows how to maximize auto insurance policy. This is something you may have invested some of the car's value, the vehicle to get back to haunt you again and again. While the second thing you spend quite a bit of research must be honest complete boredom, of changing even if it has a deductible when they re-evaluate your driving record then it covers any vehicle that is reasonable with price comparison websites, you should also take other precautions. Understanding exactly where you can purchase as well, that it no price is easy. However if you were in or pen stop until you get a cut in your state, can also be seen that the information you receive a proper education that a cautiously planned insurance strategy, together with something you'll bring to your advantage to take proper care of things to go for the repairs may be considered as reckless drivers by insurance Vendors? Many insurance companies provide impeccable back up without hitting anyone.
You want to look though and most importantly it doesn't mean that in order to get a big secret. If your cheap auto insurance quotes in Redmond, WA provides to its destination. Ensure you check your owner's manual to ensure you check the ins and smartest ways to get that there is no collision coverage, but don't mistake having car troubles may not properly insured. If you're ever in an accident that has full protection can save money by adding your teen experience that comes with all of your cheap auto insurance quotes in Washington. Once you and that they do not always make sure all of the people from the professionals. As a necessary and remember to take advantage of choosing the brand and the conflict continued. They matter because they are three types of coverage that you have an accident along with paying car finance and will do every possible insurer. Have fallen into the discussion. Rich people do to get quotes from them. You can get organized quicker with a high risk locality, you must seek out a reliable insurance company and demands $50K - the limit. Which part of any use. Furthermore, employers now routinely pull "employment reports" - which are different types of policies.

subset: commoncrawl


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Lorac poured out his soul in the new video for "I waited for you": just about Murata-San, how much pain
Popular Ukrainian singer Ani Lorak, which is now actively building a career in Russia, decided to show the fans in a new Instagram video. Celebrity put up a short excerpt from the video for the original song "I waited", which intrigued quite a long time. So, the actress posed in a short, figure-hugging outfits and admitted that the song is autobiographical. Many fans have already assumed that Carolina dedicated it to her ex-husband, Murat Nalchajian which recently divorced.
"This story is woven from my feelings, let this music will warm hearts.
#atenaide were available on all platforms", – shared his emotions Lorak. Followers began to comment: "I Love lorac,but the song is so-so," "I love Your work, but this song is not gone((", "Campaign one I did not like the song? Yeah, makes sense, and the words are beautiful… but the execution and music… all typical of how the rest of the song, gray… and damp. Did not catch the melody.. even🤦♀ I", "the Song beautiful sensual clip ,not really," "With all due respect, no song!((""Murata🤔".
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The celebrity also dressed in a short black and white dress and quite bulky boots. The image of the singer complements the heavy evening makeup, however, many did not like it.
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Honest eye for beauty
1 May 2018 | Posted in: News
For photographer Edwina Richards, it's Lynch over likes.
While so many of us spend time considering what next to include in our digital Instagram galleries, Edwina is considering her shots, right down to the tiniest shadow. It's this unmatched eye for photographic detail that Edwina has developed over the 18-month period she's occupied the Clocktower Studios;
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Fayetteville coach Drew Yoakum said he's had to bring up a few more ninth-graders than he would like to fill his teams this spring, but they have done what it takes to earn their spots on the rosters.
One freshman — Isaiah Sategna — has already made his presence felt in a big way. Sategna, the son of new Arkansas assistant track coach Mario Sategna, moved to Fayetteville from Austin (Texas) Westlake and is currently the leader among Northwest Arkansas track athletes in four events: the 110- and 300-meter hurdles, the 200 and the long jump.
"I immediately said he was going to move up to the high school team," Yoakum said. "After looking at his past and talking to his parents, there was no doubt he was going to move up."
In his first meet as a Bulldog, Sategna broke a 17-year school record in the 300 hurdles with his time of 38.32 seconds and won the event by more than 2 seconds. Yoakum said that the 300 hurdles and the long jump are probably Sategna's favorites and he puts a lot of pride in those events.
Yoakum said he sees a lot of similarities between Sategna and former Fayetteville standout Wallace Spearmon, who went on to run at Arkansas and in the Olympics.
"In my years here, I've been blessed to have kids like Isaiah that can do multiple events like this," Yoakum said. "He is very similar to Wallace in the way he runs and jumps, and having those type of kids in track has been a big deal in Fayetteville. He's definitely the piece that we had missing in this ninth-grade class."
Yoakum said he hopes to have Sategna compete in the 100, the long jump, the 300 hurdles and the 4x400 relay during today's Tiger Relays at Bentonville.
Pea Ridge takes on bigger schools
A fourth-place finish in last week's Springdale Schools Invitational doesn't seem that impressive at first glance. Pea Ridge's girls, however, gladly took that kind of performance as the Lady Blackhawks ran against Class 6A stalwarts Bentonville, Rogers and Fayetteville.
"I was very pleased with how we stepped up against the larger schools and with how we finished," Pea Ridge coach Heather Wade said. "The girls were pleased and excited."
Pea Ridge, the defending Class 4A state champion, has run against 6A-West competition in the Y-Timing Invitational and last week's meet at Springdale. It will continue that trend today as the Lady Blackhawks take part in the Tiger Relays in Bentonville.
Wade said she simply wants her team to run against quality competition and has chosen closer meets that fit well into Pea Ridge's schedule.
"Our goal right now is to prequalify as much as we can," Wade said. "Who knows when our softball team may have to alter its schedule, and we would have to be without Blakelee Winn."
Winn, a sophomore, is among the area's leaders in four categories and compiles plenty of points. Wade said senior Shelby Dunlap — who signed a national letter of intent Wednesday with Arkansas-Little Rock — is very focused and had a good showing at last year's state meet, while Jamison Toms scored points last week in the long jump and the 100 meters.
Wade said the Lady Black-hawks have a young group of distance runners that are coming together. High jumper Kynley Burton, who won the event in the state indoor meet, has yet to compete in outdoor meets and is expected to produce points as well.
Record Watch
Two Northwest Arkansas athletes have put state records in danger of being rewritten, thanks to their performances last week at the Springdale Schools Invitational.
Pea Ridge junior Cassidy Mooneyhan did it first when she won the girls pole vault, clearing a personal-best 12 feet. The Class 4A state record in that event is 11-6 set by Mena's Staci Yahn in 2006, and Mooneyhan set the indoor state record for 1A-4A schools last month when she cleared 12-6.
Meanwhile, Bentonville senior Lainey Quandt surpassed one state record mark with her performance in the 1,600 meters, where she finished in 5 minutes, 1.29 seconds. The Class 6A state record in that event was set in 1986 by Conway's Julie Jiskra, and her hand-held time of 5:01.8 carries a FAT equivalent of 5:02.04. Quandt, who has already signed to run track at Arkansas, is not far off from threatening another state record as she ran the 800 in 2:15.69 during the Y-Timing Invitational two weeks ago in Fayetteville. The 6A state record is 2:15.33 set by Jonesboro's Katya Kostetskya in 2003, while the 7A state record is 2:14.71 by Fayetteville's Amanda Agana in 2014.
State records can only be set during state meets, according to Arkansas Activities Association guidelines.
Today On The Track
Tiger Relays
WHERE Tiger Athletic Complex, Bentonville WHEN 3 p.m. for pole vault, 4 p.m. for remaining field events and running events SCHOOLS Bentonville, Decatur, Fayetteville, Pea Ridge, Rogers Heritage, The New School
Tyson Relays
WHERE Green Forest WHEN 3:30 p.m. for field events. SCHOOLS Bergman, Clarksville, Eureka Springs, Flippin, Gentry, Gravette, Green Forest, Harrison, Huntsville, Prairie Grove, Shiloh Christian, Springdale, Valley Springs, Western Grove, Westville, Okla., Yell-ville-Summit
Greenwood High School Invitational
WHERE Greenwood WHEN 4 p.m. for field events; 4:15 p.m. for girls 4x800 relay (followed by boys); 5 p.m. for all other running events SCHOOLS Alma, Fort Smith Northside, Fort Smith Southside, Greenland, Greenwood, Magazine, Mansfield, Providence Academy, Rogers Heritage, Rogers High, Roland, Okla., Russellville, Siloam Springs, Van Buren, Waldron.
Henry Apple can be reached at email@example.com or on Twitter @NWAHenry.
Print Headline: Fayetteville freshman makes fast impression


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Hatfield House is a renowned and impressive Jacobean house and Tudor Old Palace and is synonymous with both Victorian and Elizabethan history. The house is located in a stunning scenic setting, visitors to the house can also see the gardens and park that the house is set in. The house has been the family home for the Cecil family for many generations and contains a great deal of history and heritage dating from the 17th century. The Old Palace has a Royal history and had been a childhood home of Queen Elizabeth I.
Hatfield House is located in Hertfordshire approx 20 miles from central London in the renowned English countryside and provides a perfect location for this impressive historic house. The house was built in 1611 by Robert Cecil, first Earl of Salisbury, after the family home of the Cecils' at Theobalds in Hertfordshire had been exchanged for the Old Palace and manor of Hatfield.
The House was built adjoining the site of the Old Palace of Hatfield. The House was wonderfully decorated for entertaining with the State Rooms containing fine art works, paintings, furniture and tapestries. The are great examples of Jacobean craftsmanship in evidence in the house most notably in the Grand Staircase that displays its fine carving, there is also the rare stained glass window evident in the private chapel. The house displays a number of historic and heritage mementos and artefacts that have been collected over the centuries by generations of the Cecil family.
The Old Palace is considered to be one of the best examples of mediaeval brickwork in the UK and it still retains most of its original roof timbers.
The Old Palace was a childhood home of Queen Elizabeth I, in 1607 King James I exchanged the Palace for Theobalds. Robert Cecil then built a new house and in the process took down three quarters of the original palace. The Old Palace was then used as the stables for Hatfield House, until the building was once again restored by the 4th Marquess. The Old Palace is now a venue that can be hired out for occasions such as parties, marriage ceremonies and wedding receptions etc.
The Garden at the house dates back to the 17th century, new trees, bulbs and fruit trees were planted that had previously never been grown in England. Visitors to the garden can enjoy the experience of wondering through the scented garden and seeing the fountains as well as seeing the well known knot garden next to the Tudor Old Palace where Elizabeth I spent a good deal of her childhood.
The West Garden has a herb and a scented garden and herb garden, the garden suffered from some neglect in the 18th century before it was restored to past glories later on. There are huge numbers of naturalised daffodils during spring time.
The East Garden was originally laid out by the 5th Marquess of Salisbury; it has parterres and a range of rare plants which are likely to appeal to gardening aficionados. The setting is an idyllic one and provides a wonderful sight for visitors to enjoy.
The Park that surrounds the house contains some 1,000 acres of park with woodland trails and some wonderful flowers on display. Located within the park is an oak tree marking the place where the young Princess Elizabeth first heard of her accession to the throne. The park also has a play area for children and lots of open grassy areas for youngsters to enjoy themselves. There are picnic tables provided under the trees allowing visitors to enjoy an enjoyable picnic in very scenic and tranquil surroundings, enjoying the best of the English countryside.
The Sculpture Exhibition is located in the Wilderness Garden and contains selected works to reflect chosen themes. There are abstract pieces alongside other pieces to give visitors a varied experience, the sculptures take on different forms during the day as the light changes.
A trip to the house takes visitors to a fascinating house steeped in history and links to Royalty. The scenic location, marvellous gardens and proximity to London mean it is easy to get to and offers an enjoyable day out for visitors.
How to Get There
The House & Park are accessible by both car and public transport.
By Car:
Hatfield is located just over 20 miles from central London. Hatfield is located 7 miles from junction 23 of the M25 motorway and 2 miles east of the A1(M) at junction 4. From the A1(M) exit at junction 4 and follow the brown signs for Hatfield House along the A414 and A1000. The main entrance is located opposite Hatfield railway station on the A1000.
There is free parking available on site.
For those using Satellite Navigation systems the postcode to use is AL9 5NQ.
By Bus/Coach:
There are various local Hatfield bus routes that serve the area, the route numbers 610 from Enfield to Hatfield and 614 from Queensbury and 615 from Rayners Lane offer bus services from North London to Hatfield, the routes are operated by Uno.
National Express offer coach services from a choice of towns and cities in the UK to Hatfield.
By Train:
The closest train station is Hatfield train station, it is located opposite the main entrance to the Park and is a 5 minute walk to the house. From London King's Cross station there are regular services to Hatfield, the journey time is approx 25 minutes.
Contact Details
The House Office
Hatfield House
Telephone: +44 (0)1707 287010
Fax: +44 (0)1707 287033
Website: Hatfield House
Facilities & Information
Opening Times:
For the House:
From end of second week in April until end of September:
Wed to Sun & Bank Holidays: 12:00 to 17.00 (last admission at 16.00)
Closed on Mon & Tue (excluding bank holidays).
Park, West Garden, Restaurant & Shop:
Wed to Sun & Bank Holidays: 11:00 to 17.30 (last admission at 17.00)
Open daily in July & August
East Garden:
Open on Thursdays only during the Visitor Season from 11.00 to 17.30 (last admission at 17.00)
The house may have times when it is closed or closes early or operates alternative opening hours at short notice. It is recommended visitors check all opening and closing times and specific days visits are open when booking to get the latest information & avoid disappointment, as changes can occur.
Further Information:
Admission Prices:
For House, Park and West Garden:
Adult: £10.50 approx, Children: £5 approx, Concessions: £9.50 approx, Family Ticket: £26 approx
Visitor information
There is a gift shop for souvenirs and a restaurant offering hot and cold drinks and snacks including sandwiches, cakes, salads and cream teas.
View Larger Map
For Local Search and Directions see: Hatfield House Map
Tips & Other Considerations
There may be some variations on the opening hours depending on the time of year and the attraction you wish to see. It is wise to double check before going to ensure the attraction you wish to see is open and avoid disappointment.
Always remain alert, vigilant and aware of your belongings at all times especially your wallet/purse and valuables and ensure they are hidden away from public view. If you have a bag try to use a shoulder bag with a good quality, strong strap, that is put across your shoulder not on your shoulder making it more difficult for anyone to take your bag.
If you are travelling by car to Hatfield ensure you are well prepared with maps and Sat Nav to aid your journey, particularly if you are not familiar with the local area and roads. Check Road & Traffic Updates before travelling.
If you are looking for car parking close to the House, ensure you fully understand the rules, regulations & charges for car parks and street parking. The rules & regulations can be complex & confusing if you are unclear, it is wise not to park there.
If you are travelling by public transport, check for service updates prior to beginning your journey for any delays, disruption or cancellations to services that may impact on your journey. Ensure you have the service timetables for the trains, trams, buses and coaches. Remember when the last services are and ensure you make it to the train/bus/coach stops well in time to avoid missing the service.
Disclaimer: The information given in on this website is given in good faith and to the best of our knowledge. If there are any discrepancies in no way do we intend to mislead. Important travel details and arrangements should be confirmed and verified with the relevant authorities.


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We woke up around 8:30 …or was it 9:30? We were so close to the AZ/UT border and the location of a time zone change that we weren't sure of the exact time. Either way, we made our way across another dam to the Glen Canyon Visitor's Center. We gathered some information about the local beaches, Jet Ski rentals (way too expensive!), and must-see sites. The women at the information desk referred us to the Coves in the Glen Canyon National Park for a good spot to go swimming. While trying to find a good spot to jump into Lake Powell, Matt spotted a few Jack Rabbits and we saw plenty of lizards.
We took turns jumping into the warm lake off a sandstone rock. After swimming, we made our way over to the nearby beach to hang out for a bit. We were able to drive the Corolla right up to the water's edge because the sand was packed tight. We relaxed in the sun, swam in the warm lake, and napped for a few hours. Before getting back on the road, we took advantage of the showers at the Lone Rock Beach.
It was late afternoon when we finally reached Zion National Park. The park had limited access for public vehicle, so once we reached the Southern Visitor's Center, we would have to take a free shuttle bus the rest of the way down the canyon. We entered by means of the East Entrance. This route allowed us to check out Checkerboard Mesa and the Mile Long Tunnel built in the 1930s. Although we made a valiant attempt, neither Matt nor Danielle could hold their breath through the entire tunnel. Once on the free shuttle bus, we stopped at the Courtyard of the Patriarchs. Here, we ate some left over Quiznos subs before getting back on the bus to continue down into the canyon.
We admire the scenery as we rode the bus past the Grotto and Zion Lodge. Our next stop was at the Weeping Rock. This porous rock structure adsorbs water when it rains and eventually the water drips from a ledge. As we walked up to the ledge, it felt as though it was raining! On the bus, the audio tour informed us that the water dripping today was 800-1200 years old. Weeping Rock is also the location of the largest group of hanging gardens in the Zion National Park. The last stop of the evening was at the Temple of Sinawava. I'm sure this was a beautiful area, but by the time we had arrived, the sun had set and it was too dark to check things out.
We retuned to the car around 9:00 and hit the road for Bryce National Park. By 10:30, we decided to pull over on the side of the road and set up camp. It was windy and trucks were flying by, but at least we didn't need to spend another night in the car. We made a few Cups of Soup before watching a mover on the laptop and heading to bed.


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When can I.O.I's Jeon So-mi find romance?
Project girl group I.O.I's Jeon So-mi wondered out loud on a TV program Monday whether she will have to wait two or three years until she can date a man without breaching the contract she has with JYP Entertainment.
She made the comment on infotainment program "Non-Summit," where she was a guest alongside bandmate Zhou Jieqiong.
Japanese panel member Ogi Hitoshi asked So-mi what the consequences of dating were for Korean pop idols. He mentioned that a member of Japanese idol group AKB48 once shaved her head in apology following the disclosure of her romantic relationship.
Fifteen-year-old Somi explained that her contract with JYP Entertainment prohibits her from becoming romantically involved with anyone for three years.
Since starting official idol activities as a member of project girl group I.O.I, a group comprised of 10 other girls from varying agencies, So-mi has worked for a year.
Zhou Jieqiong, who belongs under Pledis Entertainment, also is contractually unable to date for three to four years.
By Lim Jeong-yeo (email@example.com)
Related article: I.O.I, Pentagon promote Elite school uniforms
[INTERVIEW] GOT7 talks 'insecurity,' hopes to win 1st place with new record
[V Report] BTS' Jin, Jimin delve into Korean food in US hotel room
[INTERVIEW] Winner on new album 'We,' Blackpink and YG scandal
[Kpop Herald x TwitterBlueroom] EXID talks new album 'We,' boasts tight-knit bond between members


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"Free will does not exist", according to Luther in his letter De Servo Arbitrio to Erasmus translated into German by Justus Jonas (1526) in that sin makes human beings completely incapable of bringing them selves to God. Noting Luther's criticism of the Catholic Church, Erasmus described him as "a mighty trumpet of gospel truth" although agreeing, "It can be clear that many of the reforms for which Luther calls are urgently essential."[forty seven] He experienced fantastic respect for Luther, and Luther spoke with admiration of Erasmus's exceptional Finding out. Luther hoped for his cooperation in a piece which appeared just the normal outcome of his possess. Inside their early correspondence, Luther expressed boundless check here admiration for all Erasmus had performed in the cause of a seem and sensible Christianity and urged him to hitch the Lutheran occasion.
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The effects of enrofloxacin on canine tendon cells and chondrocytes proliferation in vitro
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Enrofloxacin, a fluoroquinolone antibiotic has been used widely in humans and domestic animals, including dogs, because of its broad-spectrum activity and relative safety. The side effects of fluoroquinolone, induced tendinopathy, tendonitis, spontaneous tendon rupture and cartilage damage, remain incompletely understood. In the present study, we investigated the in vitro effects of enrofloxacin on cell proliferation and induction of apoptosis in canine Achilles tendon cells and chondrocytes. Cell growth and proliferation after treating with enrofloxacin for 2–6 days was quantified by a colorimetric 2,3-bis{2-methoxy-4-nitro-5-sulfophenyl}-2H-tetrazolium-5-carboxyanilide inner salt (XTT) assay. The results showed that enrofloxacin could inhibit the proliferation of canine tendon cells and chondrocytes at increasing concentrations (10–200 μg/ml). The inhibition of proliferation of canine tendon cells and chondrocytes after exposure to enrofloxacin were associated with induction of apoptosis, as evidenced by the typical nuclear apoptotic condensed nuclei found using Hoechst 33258 staining. It was demonstrated that canine tendon cells and chondrocytes treated with 200 μg/ml enrofloxacin for 4 days exhibited apoptotic features and fragmentation of DNA. Enrofloxacin also increased the apoptosis of canine tendon cells and chondrocytes in a dose and time-dependent manner. The results indicate that enrofloxacin inhibits cell proliferation, induces apoptosis and DNA fragmentation, which might explain enrofloxacin-induced tendinopathy and cartilage damage.
KeywordsApoptosis Canine tendon cells Cell proliferation Chondrocytes Enrofloxacin
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My f*k Lesufi! A zone that wide and you still run into a bad policy
With leadership like ours, the mother in that viral clip said it for all of us when she uttered: 'My f*k Marelize'
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Imagine seeing a Lamborghini left in the trench on the right while you're on the road with your car. A Bitcoin billionaire living in the UK left the Lamborghini on a highway-side ditch.
According to the news of ABC News, London cameraman Andrew Lawrance saw a Lamborghini purple in the roadside when he was on his way to work last morning. The market value of the vehicle left leaning towards the trunk was 250 thousand dollars.
The cameraman says the vehicle has been abandoned by someone who doesn't know how to drive. Because the front is facing the opposite direction, there were some pointless scratches and blows on the vehicle.
Since the driver's seat was leaning against the ditch side of the ditch, the person carrying the car there probably came out of the passenger door. They tried to reach out to the owner in case he was stolen.
The location of the vehicle was very close to the facilities of the British football team Tottenham Hotspurs. It was thought that the car belonged to a football player who had a great time for fun.
As the investigation was underway, Michael Hudson, the Bitcoin millionaire, arrived at the vehicle and told him that it was his. Hudson announced that he had lost much control over the night and had left the car in the accident area to receive it later.
Calling a tow truck came to the fore in Hudson, England and all over Europe because of its coolness, leaving the scene of the walk.


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Heidi Turco
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Rothbard boils down the Austrian theory to its essentials. The book also made huge theoretical advances. Just as importantly, it is beautifully written. He tells a thrilling story because he loves the subject so much.
Max simply replaces the word "gold" with "Bitcoin" showing how Rothbard has predicted all major events of Bitcoin in 1963. Get the free pdf and audio book thanks to the Mises Institute. https://mises.org/library/what-has-government-done-our-money Get early access to Bitcoin to the Max by supporting the channel on https://tallyco.in/HillebrandMax
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Game genres
Game settings
PC Games > Genre > Puzzle > Lost Lands: The Golden Curse Collector's Edition
Lost Lands: The Golden Curse Collector's Edition
Big Fish Games
- OS: Windows XP/Windows Vista/Windows 7/Windows 8/Windows 10
- CPU: 1.6 GHz
- Memory: 1024 Mb
- DirectX: 9.0
- Hard disk space: 1160 Mb
Life in the Lost Lands has continued peacefully for several decades since the oppression of the Black Horsemen was finally put to rest. But now, stone demon statues have begun coming to life in an abandoned old fort. The locals are panicking. No one suspects that an ancient curse has been awakened after sleeping for a thousand years. Thankfully, a mage named Maaron remembers Susan, the warrior who repeatedly saved the Lost Lands from the forces of evil. He summons her once more to the Lost Lands, because this time, it is not just the fate of Lost Lands at stake, but the entire human world... Susan's world.
- Experience a character's back story in the bonus game!
- Find collectibles and morphing objects!
- Earn achievements, and play bonus puzzles and mini-games!
- Bonus wallpapers, concept art, soundtrack, and more!
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