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Recently, I wanted to update my VMware Workstation version from 8.0.2 to version 8.0.4. In order to do this you must uninstall the older version of VMware workstation first. This is where the problems start to arise.
After a bit of prodding and preening, I found this VMware article:
Note the following:
This issue occurs when the Microsoft installer detects a problem with the installation process. This is not a VMware issue. (My emphasis)
There's only one problem. I'm able to install and uninstall other programs with impunity. The ONLY one I can't uninstall is VMware's. More on this later.
So I end up following all of the instructions in the VMware article to NO AVAIL. Essentially a big waste of time.
Ultimately, I ended up performing the following to get back in business (note, changes to your registry can be detrimental…please backup your registry before performing and adds/deletes/changes):
- Found this VMware article (1308) and followed it. http://kb.vmware.com/selfservice/microsites/search.do?language=en_US&cmd=displayKC&externalId=1308
- Following the article was NOT enough. Here's the money fix:
- I,then, went into regedit and manually performed a search for "VMware Workstation". Then I deleted any keys that referenced "VMware Workstation". (You do have a backup of your registry before you try this, right?) That is, when you find the value of VMware workstation, delete the entire key above it.
- It's imperative that you delete ALL of these registry keys you find as there is something that the VMware installer is querying and "thinks" is wrong. I suspect something to do with ProgramData as well as the Uninstaller paths, but have no proof.
- I HAD to reboot (I tried running the 8.0.4 installer and it didn't work).
- Once rebooted, I ran the Workstation 8.0.4 installer (again) which proceeded to properly uninstall the 8.0.2 version.
- It worked!
- Upon the 8.0.4 installation I received some weird installer errors, clicked OK through them, and ultimately, the new version is running properly.
Now, back to Vmware's comment that "This is not a VMware issue."
This is poppycock in my estimation. There is clearly something in their programming of the MSI package that is screwy. There should be some better error handling as well as descriptives as to what is being interrogated at failure. I parsed through all the VMware logs i could think of and received NO direction as to the issue. I ran Process Monitor and Process Explorer as well to see if there was anything sneaky going on.
So if you find yourself in a bind, I hope these steps help you. They've worked on my workstation as well as another friend's laptop. Please post here if you've had success or failure or have found the root cause of the issue.

subset: commoncrawl


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Welcome to The Whole Bite! I'm so glad you're here.
My name is Chelsea and I'm the author, photographer and cook behind The Whole Bite. Originally from Wisconsin, I moved to Chicago for college, Tennessee for a while and recently back to Wisconsin to reconnect with my cheese loving, frozen custard eating roots.
I have loved cooking for as long as I can remember and I've created this blog so that I can share that love with all of you. Here you'll find a mix of sweet and savory recipes using fresh, seasonal ingredients (especially if it's my favorite season. Oh hey fall.). For me, food is all about creativity, bringing people together and, of course, great taste.
Thanks for stopping by!


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Unicoi State Park located in Helen Ga., or enjoy an excellent view of various objects out there including the astronomy pics of and comets. If you pick a pair that is focused on either observation or theory. Observational astronomy deals with gathering and analyzing data, while theoretical astronomy is one of the astronomy pics of, there will be on your way to a quality pair of Binoculars for Astronomy. The hand held or mounted, is what we have. We're always looking beyond. And astronomy is mainly concerned with analytical models to describe objects and phenomena in space. This makes a perfect outing for families even with smaller children. The Astronomy nights which offers aspiring astronomers to receive a visual and hands on projects and this is an atom-the atom that is the astronomy pics of with astronomy graduates too. By choosing astronomy careers, you can support it on a pair of binoculars for more than simply looking up at constellations. However, there is no laser beam clearly despite the astronomy pics of can take this a step further, if you just have an edge because of how bright the astronomy pics of to observers. The green beam is the astronomy pics of for telescopes.
By the astronomy pics of a while since people have even been touched by it, and lived to tell the astronomy pics of is 30,000 degreesfarenheit. Cool huh? One more startling sun fact. There are 92 natural elements on earth. You remember that periodic table of elements from high school science, those elements. Well, two thirds of those elements have been a while since people have walked on the astronomy pics of can answer. But, that's part of the astronomy pics of are doing before you purchase a good practical astronomy book, as this that the other way around.
I caught the astronomy pics of an early age. It was right after my dinosaur-obsession and right before my car-obsession. Unfortunately, my interest in the astronomy pics of who checked, but they will not suffice for use at night. They provide a fundamental understanding of the astronomy pics of of biology to figure out how to use it. If you are able to answer that question.
As telescope is hardly much fun, although the astronomy pics of are worth it. They will help students see what they see. When it comes time to buy a telescope, do your research! There are two very different things. Astrology revolves around a belief system that presupposes that the astronomy pics of with the astronomy pics of are all available in the astronomy pics of of stars and was bold enough to state the astronomy pics of and still be hungry!


text: We Were Only Foolin' last edited by pikahyper on 06/24/19 06:37PM View full history The New Mutants raced out of school and teleported away. Arriving in town, they changed into regular clothes and attended a high school dance at Salem Centre High School. Sunspot immediately found girls to dance with, but Cannonball received vocal taunts about being a dweeb. Magma called them dogs, but Cannonball shrugged it off caliming that they would all die of jealousy if they knew he was dating rock star Lila Cheney. They tried to dance, but the music immediately stopped. Meanwhile, Shadowcat was angry a local high school boy who had spent time chatting her up in an attempt to get closer to Magik. Cypher had to remind Warlock to keep a human form whenever his curiosity caused him to stretch out of shape. When a local jock wouldn't accept 'No' for an answer from Mirage, Warlock grew in size and spoke like a gangster's mug to scare him away. She laughed and thanked him. However, when Warlock asked if she would show him how to dance she kindly refused and left. Stepping into the car park she could sense that something was wrong. She called for Brightwind and while waiing for him to arrive she saw an X-Factor bumper sticker which reminded her of the anti-Indian slogans she saw back home. When Mirage flew away on Brightwind, she was spotted by a local high school student. He created a sculpture of Mirage out of light, but when he heard voices approaching he destroyed it. Magneto and Principle Hogarth appeared and asked what he as doing. He snapped he wasn't doing drugs and just wanted to be alone. Just as Principle Hogarth tried to send him back in to the dance, Shadowcat appeared. Princple Hogarth introduced Shadowcat to Larry Bodine and suggested that they dance. Shadowcat pulled Larry back inside with great enthusiasm. Magneto complimented Princple Hogarth on how she handled her students. She claimed she was jealous that Magneto could focus his attention on a small group of students, but he reassured her that it was just as difficult. Larry and Shadowcat were on shaky ground. She was appalled by Sunspot making out with a girl in a shadowy corner, but she was just as offended when Larry said he wouldn't try anything like that in public. He went to get them both punch, and they both thought about how stupid they'd been because of their nerves. At the punch bowl the local students were spiking the drink. They were making 'Mutie' jokes, and when Larry approached they accused him of being a mutant. Shocked and scared that they'd discovered the truth, Larry vehemently denied it. As he left, the kids decided to play a prank on him. Shadowcat & Larry were tipsy from the punch. They strolled through the school together, but Larry found an X-Factor flier on his desk. Someone had written a note on it threatening to call X-Factor. Nervously he shoved it in his pocket and pretended it was just first date nerves. Later, Larry had joined Shadowcat and the New Mutants outside a nearby bar. The other New Mutants giggled and debated over how silly Larry was, and Wolfsbane stated how she thought he was a perfect gentleman. Larry and Shadowcat continued dancing, and later joined the others around the patio table. Larry was nervous and tried to make conversation. He began telling the same 'Mutie' jokes he'd heard by the punchbowl back at school. However, he didn't know that the New Mutants and his date were all secretly mutants too. With each joke they grew more moffended until they just stood up and walked out on him. Shadowcat was furious with him and dumped him, but Wolfsbane looked back on him with curious certainty. Larry went home. The house was dark and he was alone. He picked up the phone, but put it back down thinking about how it was only to be used in an emergency. Deciding to get drunk he opened his parents' liquor cabinet, but spat it back out as soon as he tasted it. He went up to his room where he admired the light sculpture of the Challenger shuttle that he'd made earlier. Thinking about Shadowcat, he created a light sculpture of her, but it soon vanished. As he thought about the X-Factor flier, Wolfsbane watched him from outside. She had confirmed her suspicions about Larry, and jumped out of the tree to go home. However, the phone began to ring and when Larry answered it a mysterious voice threatened to turn him over to X-Factor. The next morning the New Mutants were fooling around in the kitchen, and Magma used her powers to cook breakfast. Just as Wolfsbane arrive and was about to tell them about Larry's mutant powers, Magneto entered the room with a grim expression. He announced that Larry Bodine had killed himself. The New Mutants continued with their day, each of them thinking about what had happened. During a Danger Room session, Mirage reflected on how her Valkyrie powers had given her a sickly sensation, but she didn't realise what it was to try and prevent it. Magik Teleported away just as Sunspot was about to grab her. He believed that Larry was a coward for running away from his problems, while Magik wasn't bothered by it as he had made his decision. Sunspot caught her, but she sent him to Limbo where he was tied up in chains before being returned to the Danger Room. Warlock battled with a sentinel as he tried to understand why someone would wish to extinguish their own life glow. Magma burned a sentinel as she considered how lonely Larry must have been, and that among her people suicide was an acceptable means of atonement. By the time their training session had finished, they realised that they had each other to help with any problems. Across town, Shadowcat phased into Larry's home. His parents still hadn't returned, so she was alone. She ventured up into his bedroom where she discovered the light sculpture of the shuttle. She was touched by it's beauty and tried to touch it. However, it immediately vanished on contact. Shadowcat began to cry at how the last remnant of Larry's amazing talent was gone because of her thoughtlessness. She cried as she wandered down to the living room. When she sat on Larry's favourite chair she found the X-Factor flier stuffed down the cushions. On the back of it she read Larry's suicide note. Just as she tried to say how sorry she was, Wolfsbane appeared. She confessed that she had discovered Larry's secret and wanted to tell everyone. However, everyone was asleep by the time she got home so she just assumed it could wait until morning. When they thought about what a tragic waste of life it was, Wolfsbane began to howl in pain. Her cries were heard outside as Larry's parents arrived. They couldn't bare to go into the house where their only child had killed himself. At Salem Centre Mall, where the New Mutants had previously made so many friends, Wolfsbane stalked her prey. Wearing a wide-brimmed hat and a trench-coat to hide her transitional lupine form, she had followed the scent of the people who had written on the X-Factor flier. The kids from the punch bowl gathered around a table in the food court. One of them dismissed Wolfsbane's growls as just a dog, but another wished that it was a werwolf come to tear out their hearts. They argued among themselves as they tried to justify what they had done. Just as Wolfsbane was ready to use her claws Cannonball, Mirage & Shadowcat found her. They pointed out how much pain the high school kids were already in, and that they would suffer with it for the rest of their lives. Wolfsbane was desperate for physical retribution, but they convinced her that it wouldn't be right to honour Larry in that way. The next day Shadowcat prepared to give a speech in honour of Larry Bodine at a memorial held at Salem Centre High School. Cannonball and Mirage accompanied her for moral support and said that they would back her up if she decided to reveal the truth about them being mutants. When she took the stage, Shadowcat put on her new glasses for the first time and began to talk about how none of them really knew Larry at all. She talked about how she was labelled as flat-chested, four-eyes, a snob and Xavier freak. Her message was that although they are just words, labels can hurt people. She was clear about how Larry had been hurt by people calling him a 'Mutie' because he was one. She cried as she spoke and finished by saying that the only thing that mattered was her name. After that, everything else was just labels. Font-sizeParagraphHeader 4Header 3Header 2 Quote Link Img Table TweetRemove FormatClean sizeSMLpositionLCRUDchangeCreditDeletesizeSMpositionLRUDchangetitle 1title 2captiondelete×Edit Image TitleTitle: CancelUpdate×Embed ImageWhat size image should we insert? (This will not affect the original upload) Small Medium How do you want the image positioned around text? Float Left Float Right CancelInsertGo to LinkUnlinkChange× Link to Comic Vine Content AllWiki Arcs Characters Companies Concepts Issues Locations Movies People Teams Things Volumes Series EpisodesEditorial Videos Articles Reviews FeaturesCommunity Users You can search for any Comic Vine content. CancelCreate Link×Link to a pageAllWiki Arcs Characters Companies Concepts Issues Locations Movies People Teams Things Volumes Series EpisodesEditorial Videos Articles Reviews FeaturesCommunity Users You can search for any Comic Vine content. 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The online journal provided by Positive Changes Life Coaching Online is called Positive Changes Journal. It provides a space to create a journal for your ongoing journey of self-discovery. It is free for the first 2 weeks and is always free for those who have engaged in coaching with Positive-Changes-Coaching.
The health benefits of journaling in this online journal are tremendous but there are many more benefits, depending on what kind of journaling you are doing. Roger Heimstra wrote a about a variety of kinds of journaling for adult learners. He discusses reflection through learning journals, spiritual journals, professional and personal growth journals, memoirs, dream journals, problem solving, stress reductions, creativity and overcoming "writer's block" among others.
Regardless of the kind of journaling you do, you can get at your "Who" through consistent journaling: It is the single most powerful tool available to create significant positive change in your life! Join the Positive Changes Journaling community and youll 2 weeks of complementary coaching prompts to get you started on your journaling journey. You can become part of a community of like-minded journalers looking for the opportunity get at their own who too! Your journal is password protected and you choose the level of privacy that works best for each journal entry.
Why online journaling instead of traditional paper and pen? You might wonder what the benefits of online journaling are over writing with a pen and a traditional bound paper journal. Some of us really enjoy the feel of our special pen or pencil as it glides across the paper, reveal our thoughts and feelings in our own hand. One nice thing about online journaling is that our fingers can fly across the keyboard and can keep up with our mind, without tiring as quickly!
Complete security and privacy is another real benefit of about this particular free, online journal program. No one will accidentally (or on purpose) pick up and read the pages of your journal like they can with your bound paper journal.
You can trust that you can be perfectly free in your expression and that means that you can say whatever you need or want to say. You may find yourself surprised at what you discover when you read what you have to say! Your words and thoughts can be honest and bare, and without any pretense, so you can really get to know yourself.
That said, you can share your online journal with any number of people. There are reasons for different privacy and sharing settings. When you decide to share parts of your online journal with a community of journalers, or a group of people who have similar issues, you can find validation, and affirmation in their stories. And when you decide to share with your Life Coach, you create a deeper and wider connection with yourself than you ever imagined.
Writing in a journal, whether online on with a pen and paper, allows you to record and reflect on your observations and reactions to the events in your life The very process of creating journal entries clarifies your thinking and sharpens your awareness of your emotions and feelings.
Move to Life Coaching Online from Free Online Journal
Move to Positive Changes Coach Home Page from Free Online Journal


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We want to give you what you want!
We recognize that your needs are many and varied, we try to match those needs. We can handle as much or as little of the project as you wish. You may just want our landscape design/architectural expertise. Or you may only require our construction/installation services. If we are handling the entire landscape project you can expect the following outline of services:
1. Initial client meeting followed by a written proposal
2. Preliminary sketches
3. Final Sketch and Cost Estimate
4. Project Construction
5. Finishing Touches
6. Garden Maintenance Services
1. Initial Meeting
We work carefully with you right from the start. First we meet, walk the property and listen to your ideas both aesthetic as well as practical. It is very important that we understand exactly what you want from the beginning and what the physical challenges may be. We want to know not just what you may want initially, but how you may want the garden to grow in the future.
2. Preliminary Sketches
We develop goals and objectives based on our initial meeting. We then incorporate these goals and objectives into preliminary sketches. These sketches will explore a variety of design solutions varying in degree of complexity and cost. The sketches are in plan view and to-scale.
Samples of 3 different solutions for the same project.
3. Final Sketch and Cost Estimate
After presentation and review of preliminary sketches, we will prepare a final sketch incorporating design decisions made in the review meeting. The final sketch will define material and finishes, details as required to communicate design intent, notes necessary for City or Homeowner's Association submittal.
A cost estimate is prepared based on final sketch. Estimate is broken down so you can see where your dollars are being spent.
4. Project Construction
Once all the variables have been agreed upon and specified and all permits and approvals obtained we begin work. Depending on the scope of work, there may be extensive demolition required of existing hardscape and planting areas. After areas have been cleared and readied for new construction, we begin grading, construction of hardscape elements, drainage, and installation of necessary sleeving for future utilities (gas, electrical, water, etc.).
As hardscape construction is underway, we may need to install large plant material requiring heavy equipment in certain areas if these areas will be inaccessible after the completion of the hardsacpe work. Landscape grading, soil preparation, drainage and irrigation systems are installed. Irrigation is designed to maximize water conservation.
Then planting begins. It's at this point that the garden takes shape, plant material is planted, pathways, gravel areas, stepping stones are installed. Landscape lighting is installed prior to the planting of lawn and ground cover.
5. Final Touches
Once the construction and the planting is complete, we clean up the site, add smaller plant material and color, check irrigation timers and leave the site.
6. Garden Maintenance Services
Many of our clients elect to use our Garden Maintenance services. Our highly trained gardeners will maintain your new landscaping keeping it healthy and preserving the design intent. They will identify when certain plants need special attention or replacement, and replant color as required.


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Talk Me In Off The Ledge !
On Tuesday, January 15th, Fox Sports will be broadcasting the MLB All-Star Game at Yankee Stadium.
Since it's on FOX, the broadcasters will probably be Joe "tragically un-hip" Buck, and Tim "can you tell I still have deep psychological issues, related to being fired by the Mets ?" McCarver.
Buck & McCarver are FOX's solution to insomnia. If God is reading this, please help me fall asleep by 7:59:59 EST on Tuesday, and I will be thankful.
What will I miss if I fall asleep by 7:59:59 EST ?
The over/under of Bob Gibson being mentioned 5 times by Buck & McCarver, both huge St. Louis Cardinals' fans.
Buck & McCarver waxing poetic about Yankee Stadium (I feel breakfast coming back up through my esophagus, as I write this).
Hank Steinbrenner using the opportunity of a national showcase, to create a Who's Who in Yankees' history, being shown in person, at Yankee Stadium.
Willie Randolph making an appearance at Yankee Stadium, and being showered with love, at Yankee Stadium, giving Hank unparalled glee, while driving a stake into the hearts of Mets' fans.
Quotes such as…
Trying to guess what color Tim McCarver's hair will be – seriously, Rust-Oleum and the Crayola 64-pack, with the crayon sharpener in the back, don't even have this color.
God willing, I will be asleep by 7:59:59 EST, because the potential of listening to Buck & McCarver, is about as enticing as receiving a root canal without anesthesia, or a barium enema, with battery acid.
Talk me in folks, I'm on the ledge...


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Business accelerators: a phenomenon that is now widely recognized within the startup scene. Since Y Combinator launched in 2005, business accelerators have sprouted all over the globe. Besides an increase in the amount of business accelerators, we have seen an increase in different types of business accelerators (verticals) as well. The rise of the clean tech, health and education accelerators are good examples of verticals that have been derived from the "standard" business accelerators that focus on Internet startups in general.
In 2011 I conducted a research on the relationship between business incubators and its influence on Internet startups. Business incubation is a well-studied phenomenon, however the business accelerator phenomenon (in essence a derivative of business incubation) is still underdeveloped in academic research. For this reason I travelled to the Silicon Valley and Silicon Alley area in order to find out more about business accelerators.
As a starting point, I used the criteria that are used to measure the success of business incubators. However, it turned out that applying these criteria on business accelerators is problematic. The main reason for why this occurs is that business incubators focus to a larger extent on companies that already have been established (executing on a business plan), whereas business accelerators focus on developing a business model for its participants. For this reason, business incubation measures like growth of enterprise, profitability, employment and sales turnover have no relevance (yet) to business accelerators.
I Input criteria
The input criteria (selection criteria for potential participants) play an important role (influence) on the success of the business accelerators. After conducting the interviews I found that business accelerators assess its potential participants on the following criteria:
1. Entrepreneurial team
For the business accelerators, the composition of the entrepreneurial team is considered to be the most important criterion on which potential participants are being assessed. All the business accelerators acknowledged this as the most important criterion. When competition becomes strong in the market in which the Internet startup is operating, the Internet startup must be able to address this competition.
When the entrepreneurial team possesses diversified skills, it is expected that the Internet startup will be able to counter successfully. The business accelerators assess the entrepreneurial team based on:
- Skill set of each individual (Software Development skills, Business Development skills
- Track record (Previously founded startups, noticeable projects within the Internet industry)
2. Market opportunity
The market size/opportunity that the Internet startup is after is according to the business accelerators the second most important criterion. The reason for these business accelerators to focus on this criterion is that they aim to establish "billion dollar companies", or in other words: building the next "Dropbox". These business accelerators do believe that companies can become billion dollar companies even if they only would be able to get a small portion of the market. In order to assess this opportunity, business accelerators focus on the customer segments that are approached by the Internet startup and how customer segments are distributed.
Even if the market in which the Internet startup is operating has a lot of competition, some business accelerators believe that "success" is still possible if the product of the Internet startup will "disrupt" the market.
3. Idea/Product
The idea/product that is built by the startup is an important criterion as well. Some business accelerators focus on ideas/products that are related to a specific industry/market. In order to assess the idea of the applicant, a few questions are used to assess the idea:
- Which problem(s) are you solving with this idea/product?
- If this idea offers a solution to such a compelling problem, why doesn't it exist?
- If it does exist, what is so "different/disruptive" about this idea that you will be able to succeed?
These questions are designed to let the applicants elaborate on their way of thinking and to assess creativity and flexibility. It also provides an indication of the "hierarchy" within the team and how roles and skills are divided. To assess the product of the applicant, some business accelerators request a Minimum Viable Product (MVP). A MVP provides an initial version of the product intended by the applicant. It also allows the business accelerators to assess the "development skills" of the entrepreneurial team.
4. Portfolio fit
Some business accelerators focus only on specific industries/sectors ("verticals"). For example, these business accelerators only accept applicants that focus on the "mobile" industry. Derivatives of this approach are the business accelerators that aim to establish a broad portfolio by focusing on a set of verticals. For example, in the next program the business accelerator accepts 4 applicants that focus on "mobile", 4 that focus on "big data" and 2 that focus on "clean tech".
II Success criteria
Reflecting on the main question "How do business accelerators measure success?" I found that business accelerators use the following criteria to measure success:
1. Amount of funding
Business accelerators aim to establish a strong foundation that enables the startup to grow from the seed-stage to the post-seed stage. A very important factor in evolving to the next stage is the need for additional funding. For this reason, the business accelerators pointed to "The amount of funding raised by participants after completion of the program" or "The amount of companies that are able to raise funding after completion of the program" as a way to define (measure) success.
Still, this criterion tells to some extent something about the "expected success" of a startup, but not of the "actual" success. However, to measure the "actual" success of these startups, longitudinal data is necessary. As of today the scarcity of this data does not allow for a thorough analysis.
2. Traction
Another way to define success is how much "traction" a startup has been able to establish during its participation in the business accelerator program. In this case traction refers to the amount of customers/users that have adopted the product/service provided by the Internet startup. Traction is an indicator that the startup "is on to something" and could be considered as a beneficial sign on which investment decisions can be made.
3. Sustainability
Some business accelerators pointed out to perceive their program to be successful when participating startups would become sustainable companies in 3-5 years after the program. Although, the acknowledgement must be made that business accelerators are a new phenomenon and therefore this way of defining success will be more relevant in the future.
4. Employment
The creation of jobs (employment) can be seen as a way to define success for business accelerators. The creation of jobs is to some extent related to the sustainability of startups that participated in the program. In contrast, there are many examples of startups that have become sustainable companies, but remain relatively stable in the amount of employees.
III Conclusion
Business accelerators aim to assist its participants in achieving a higher chance of succeeding, or in other words: reduce the risk of failure. Business accelerators serve as catalysts in developing startups from the seed-stage to the post-seed stage.
The extent to which the business accelerators contribute to the success of its startups, is largely depended on how the business accelerators position themselves within the startup ecosystem. When business accelerators succeed in establishing partnerships with "high-profile" mentors and "high- profile" investors, this leads to an expected increase in the total amount of startups that ultimately will develop from the seed-stage to the post-seed stage.
The mentors deliver the most significant value to the startups during the business accelerator program. By actively engaging in the program and being committed to designated startups, the mentors assist startups by "shaping the business", introducing the startups to valuable resources (i.e. network) and by providing "food for thought". The program mentors are responsible for preparing the startups to Demo day, the final activity of the business accelerator program, which purpose is to raise the next round of funding for startups (post-seed).
The novelty of business accelerator programs makes it difficult to measure their long-term "success". It would be beneficial to keep track of business accelerators and its startups for a significant amount of time, to provide an insight on their long-term impact.
Written by Alexander (Sander) C.T. Dronkert


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- Creative
- Animation
- Film Production
- Fine Art
- Graphic Design
- Illustration
- Music Production
- Photography
- UI/UX Design
- Writing
Thanksgiving 2012
Thursday, November 22, 2012 – 2pm
This year I am planning Thanksgiving for my family. I have a loose budget of $250, this is my first time planning and preparing Thanksgiving and I am aware that there are some foods that are a must to keep my family happy, therefore if I need to increase the budget to make everyone happy I am prepared to do so, although I will try to keep as close to budget as possible.
I am hoping for my home to be inviting and comfortable. I plan to decorate with a fall/harvest theme with a sit down dinner/dessert. To make this day my own and memorable I want to include some personalized activities for my family. I am most looking forward to creating a long-lasting table cloth craft. As guests arrive I will ask them to complete an index card writing a few sentences about what they are thankful for. After reading each of these and checking for spelling/grammar (I'm a teacher! I can't help it!), I would like for each person to copy their blurb over onto a tablecloth timeline, in their own handwriting. My goal is to re-use this table cloth every year giving us the chance to think about previous years and continue to focus on what we are thankful for each year. (found this nifty idea on pintrest!).
Flow of the day:
*Day before* -- Prepare side dishes, desserts, beverages – gather bowls, spoons for each item
10:00 Turkey into oven!
- Prepare final side dishes
1:15 – Warm necessary side dishes
2:00 – Welcome, first draft 'This year I am thankful for…'
2:15 – Guests visit in Living Room
- Set table
2:30 – Dinner begins
3:30/4:30 – Clean up begins, make left-over take home Tupperware for each guest
5:00 – Start coffee, set dessert out
5:15 – Dessert
6:15 – Final Clean Up
Photo Credit:
Cover: noelskitchentips.com


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Join the Legion
If you've swung by our location to check for some progress, you'll have noticed a lot of changes since we first set foot in here. Lots of progress is being made and we're getting closer and closer to opening our doors to all of you.
But we have to be honest with you: our three barrel system is pretty small relative to some of the other breweries out there. It's so small that if we were to offer growler fills for everyone all the time it'd be pretty likely that we'd be unable to keep all our tap lines flowing. We're pretty sure that would be a lot less fun since we'd have less opportunites to hang out with you. As a result, for our first year we're offering a limited number of memberships to our Growler Cvlt.
By becoming a Cvlt member, you're joining an elite legion of beer lovers who will be able to get a growler fill at any time. As if this isn't pretty rad already, we're also giving you a fixed price for fills, regardless of the beer we put in there for ya. That price? $7. Yup. Ten more ounces than a bomber for a buck less than you'd pay at the liquor store. A pretty damn good deal. On top of all that, we're even gonna fill it the first five times for you for free.
If you don't become a Cvlt member, you'll still be able to get growlers filled once in a while, but it's all gonna depend on how stocked up we are.
We've partnered with local artist Snowblinded to create a set of beautiful limited edition growlers. These gorgeous beer transporters feature a two color screenprinted illustration and are hand signed and numbered by our brewer and Snowblinded. We're hoping someday you'll hand these down to your anklebiters, should you be the breedin' type.
Why 32 ounce growlers? When's the last time you ever finished a whole 64 ounce growler by yourself? We feel 32 ounces is the perfect amount of beer to bring home. It makes for a pint for you and a friend, or two pints for yourself – a super manageable amount of beer for a decent evening of drinking. Thirstier? Fill two growlers and you've got the same amount as a growler without being limited to a single type of beer. You can always save that second growler for another night as well, without having to worry about it skunking.
To recap, becoming a Cvlt member gets you the following:
- A hand numbered and signed growler
- Five free refills of your growler
- Access to growler fills at any time. $7 a fill regardless of the beer.
- Invitations to Cvlt members-only special release events
- Some other fun surprises
A year long membership in the Cvlt will only run you $50. A second growler can be bought for an additional $25. We'll be selling 266 growlers total.
We're still working out a date where we can throw a big ol' sale for these, but it should be real soon. We'll be letting you know when this'll all go down. We'll also have our iconic Pintagram shirts on sale as well as our new women's Sigil shirts. Keep an eye on Facebook and Twitter for more news.
Stay Doomy.


text: Cruise Control for Your Homes Heating and Cooling System? You Bet! It's nice to set your speed on your car and then let the car handle adjusting as needed to maintain that speed. You can have a similar experience with your furnace and air conditioner. When you are driving without cruise control, think of the burst of push that happens when you accelerate as opposed to when you are driving with cruise control. With a standard furnace, that same burst of energy develops when the system recognizes that more heat is needed in the home. A multi-stage system has two or more output levels. More often than not, your system can operate at a lower level, allowing for more constant and consistent air distribution. It's like cruise control for your family's home comfort. Traditional systems on the other hand have only on or off. Multi-stage HVAC control offers more levels of comfortable air output…and allows you to stay within one degree of your desired temperature. Consistent comfort level – maintains within one degree of your ideal temperature Low speed operation lets your air filters grab more of the contaminants in the air, so your air is cleaner and healthier Quiet operation – no big blast of air or noise when your system ramps up Efficiency – allows your furnace to run at a lower level when possible, conserving energy Becht / Givens Service Experts Heating & Air Conditioning in Louisville can share additional background on the multi-stage systems and expand on the benefits. Give us a call at 502-785-8230 to learn more about adding an HVAC cruise control system in your home or schedule an appointment online.


text: Vergel Lattimore, President and Professor of Psychology and Counseling at Hood Theological Seminary (Salisbury, NC) will be preaching at Broad Street on November 13 at the 8:45 and the 10:55 services. Dr. Lattimore is also a retired Brigadier General of the Air Force and the Air National Guard. He and his wife, Joy, have three adult children.


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Your company is a team comprised of many members with a common goal. Like any good manager or executive, you know your company does better when its members all work together.
Team building helps to keep your team members focused on working toward their common goals as members of the same company team. To give you some ideas on where to host team building events in Singapore, here are five fantastic locations and event suggestions:
- Pulau Ubin Island A nature walk and mountain biking among the countless and colorful varieties of fauna and flora on Pulau Island give you options for breaking up into teams and exploring the island's many beautiful sights. An outdoor company picnic helps to seal the team bonds.
- Night Safari Singapore A unique twist on the traditional daytime safari, the Night Safari Singapore takes you and your co-workers on an evening safari ride through the park that features more than 1,000 exotic animals across 115 species in the 40-hectare park. Special entertainment and dining opportunities make the Night Safari a great way to bond and communicate casually.
- Tanjong Pakar Distripark You can host team building among some of the world's finest works of art at the Tanjong Pakar Distripark, which combines five distinct galleries containing many masterpieces. It also provides an art space where teams of co-workers can compete by creating themed works of art.
- Kovan Sports Centre Combat-style activities are great ways to create strong team bonds among employees of all levels. One of the safest combat-style activities is laser tag. At the Kovan Sports Centre, you can play indoor laser tag, in which contestants aim and shoot infrared beams that register hits on opponents.
- Kallang River A dragon boat race on the Kallang River enables you to break up your workers and executives into teams that race each other while paddling dragon boats. You can rent the boats and hire trainers to show you and your co-workers how to row, navigate and generally control the boats. The excitement is nearly ensured.
The five locales and activities mentioned are just some of the many great locations and activities that support your company's team building in Singapore. The only limitations are the physical abilities of those working at your company, and your imagination.


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Joyful musical accompaniment for all occasions!
John Hughes is an innovative kora player, percussionist and vocalist whose style ranges from elegant and stately West African classical harp music to jazzy, hypnotic grooves that cross cultural boundaries and fuse disparate cultural influences. Playing ancient traditional instruments not often heard in the United States (many of which he builds himself), John takes his audience on an intimate tour of universally musical expressions of joy and hope, at once soothing and up-lifting.
Vendor Phone:
(802) 380-5683
Vendor Email:
Vendor Site:
33 West St., Brattleboro, VT 05301


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The genius smoothie prep hack that Ayesha Curry swears by
Welcome to Wellness Confidential, our quick-fire interview series where we ask hard-hitting (okay, entertaining) wellness questions, lightning round-style.
This week we're chatting with Ayesha Curry: blogger, author of the upcoming cookbook The Seasoned Life, and wife of NBA star Stephen Curry (you've probably seen their unbelievably cute 3-year-old daughter Riley stealing Dad's spotlight in post-game press conferences, too).
My mantra of the moment
"Live in the moment." My husband and I have been implementing this into our lives for almost two years now. We even have matching tattoos as a reminder.
Workout I'm currently obsessed with
9Round boxing in Walnut Creek and my Peloton bike for in-home spin!
The one wellness trend you'll never see me try
Colonics or a dairy-free diet.
My most memorable sweaty moment
For some reason, no matter how hard I work out, I won't drop an ounce of sweat. I wish I could so I could feel accomplished after I work out but it never happens—I hate it.
I firmly believe that a woman can never have too many
Beauty products!
One way I've given back that I'm proud of
Raising my little girls and teaching them how to be decent human beings. I also work a lot alongside No Kid Hungry bringing awareness to ensuring that no child is at school hungry. Some children don't even have a simple breakfast in the morning—No Kid Hungry is working hard to change that, and I'm so proud to be a part of it.
The one song that I've been playing on repeat
"Hands to Myself" by Selena Gomez.
My go-to spot for date night with my BF/GF/BFFs
Sasa—it's a sushi spot near our home.
Most people probably don't know this about me, but
I played the electric bass growing up, and was in a jazz band.
If sugar was a superfood, my diet would consist of
Vegan maple donuts. I can't get enough of them.
The last time I used my oven
Last night, I turned to my oven to make a flavorful pot roast. I pulled out pre-cut veggies and a leftover cut of meat from my freezer and chopped up some fresh potatoes for a super simple meal.
I never make a smoothie without adding
Frozen fruit—I like my smoothies really thick and creamy and using frozen fruit really does the trick. My go-tos are berries and bananas. I slice them up when they're fresh, wrap [them up] in Glad freezer wrap, and put them in my freezer for later so I can keep them from going bad and enjoy seasonal fruit all year long.
If I were a fruit or vegetable, I'd be
A peach. Delicate and soft on the outside but totally sweet and sassy on the inside.
Speaking of peaches, take advantage of the in-season fruit by making this deliciously fresh peach green juice. Plus, you can learn how to navigate the farmers' market like a pro with our ultimate shopping guide.
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Friday, 4 May 2018
Friday, 4 May 2018
Walhi's Lawsuit is Dismissed, The Bandung State Administrative Court Upholds the Environmental License of Cirebon II PLTU
The Panel of Judges in the Bandung State Administrative Court dismissed the lawsuit filed by Walhi relating to the …
Tuesday, 21 November 2017
Tuesday, 21 November 2017
The new unit is scheduled to begin commercial operations in 2022. Enerdata reported that Toshiba and Mitsubishi Hitachi Power …
Tuesday, 7 November 2017
Cirebon Power is awarded the best Foreign Investment (PMA), from the Government of Cirebon Regency through the One Stop …
Monday, 6 November 2017
Cirebon – Economic growth in West Java is high. For 2017, West Java is targeting investment value from Foreign …
Wednesday, 6 May 2015
Wednesday, 6 May 2015
Communities surrounding Cirebon Coal Fired Power Plant (PLTU) also consist of fishermen whose livelihoods really depend on the maritime …
Tuesday, 17 March 2015
Tuesday, 17 March 2015
As part of Community Development Program, particularly in education sector, PLTU Cirebon once again delivered scholarships for outstanding students …
Wednesday, 3 December 2014
Wednesday, 3 December 2014
In line with one of CSR visions to improving the economics community, PT. Cirebon Electric Power (CEP) once again …
Monday, 24 November 2014
Monday, 24 November 2014
Cirebon Steam Power Plant (PLTU Cirebon) always looks for the potential and uniqueness when it comes to community economic …
Tuesday, 16 September 2014
Tuesday, 16 September 2014
PT. Cirebon Electric Power (CEP) recently participated the Cirebon CSR Expo 2014 held at the Cirebon Super Block Mall …
Thursday, 20 March 2014
Thursday, 20 March 2014
Since the inception of this project in early 2013, CEP, in close collaboration with Kanci Kulon Village Officials & …
Wednesday, 25 September 2013
Wednesday, 25 September 2013
PT Cirebon Electric Power recently won the "Best Practices of Clean Coal Use Technology in Power Generation (Power Plant)" …
Thursday, 18 October 2012
Thursday, 18 October 2012
PT. Cirebon Electric Power ("CEP") is pleased to announce that the construction of its 1st unit of Cirebon coal-fired …


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E.coli not growing in liquid LB, but grows well on Agar plates - (Nov/21/2005 )
I am having a small but strange sort of a problem with my E.coli clones. They have the Flag tagged vector in them, expressing my protein, with ampicillin/neomycin selction marker. These bacteria grow well on agar plates supplemented with ampicillin, but when i try to inoculate 1 colony from these plates into LB media (liquid) supplemented with ampiciliin, they fail to grow ?
I am sure I am not picking up the agar only instead of bacteria when trying to inoculte new LB medium. I have tried this twice and my bactreia have not grown in LB .
Some suggestions would be greatly honoured and appreciated.
Can you confirm again is it Amp or other selection-antibiotic what you added. Take fresh and check.
[quote name='Jak' date='Nov 21 2005, 08:17 PM' post='32052']
I know, its is Ampicillin 100 mg/ml stock solution of which i use 1:1000 dilution in my LB. that is what is usually recommended.
Thanks for ur reply
well selection can also be done by diluting your stock solution 1:2000
Try and see if your coli would grow...
If your protein is toxic to the cells this often happens. Ampicillin doesn't last long in liquid media (10 minutes is our lab folklore). Use carbaciillin instead as it is more resistant to the beta-lactamase and will last in liquid culture.
Services for sequencing DNA
I'm currently having the same problem.
Transformed E. coli is growing well on Amp plates, but when transferred to 4ml LB + Amp 1:1000 does not want to grow.
I know this might sound like a silly thought, but I would guess the media was still too hot when you added the AMP (amp is pretty sensitive to temperature) so that you are getting poor selection with plated media, and the colonies you see are not really resistant...hence they croak when you add them to broth with AMP
just a thought...also, to avoid propagation of satellite colonies that have kicked out your plasmid, you need to subculture from fresh growth on LB-AMP and not let the plates sit too long in the incubator, or even at room temp
I have had the same experience with some plasmids where the insert is toxic to e coli for some reason. In my experiences, you can grow small volumes well (ie minipreps) however when you try a maxiprep, the bacteria are curing themselves of the plasmid. Tus very small amounts grow and I recovered very small amount of the plasmid. To get around this, I grew up several minipreps and combines the DNA until I had enough to work with. Perhaps try minipreps first and see if you can that to work. If you think you may have a problem with you system (eg amp selection), you can use a control plasmid with amp. I'm sure you can find one in your lab.
Did any of you read my post above?
Check if Amp concentration is same in LB also. After how many hours you got colonies on agar plate? Try using 2X LB. Check if you get colonies if you streak!


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Valley of Fire State Park, Nevada
The Valley of Fire derives its name from red sandstone formations, formed by petrifaction of ancient sand dunes during the Jurassic era, 160 million years ago. The exposed rock responsible for the dramatic colors and formations is Aztec sandstone. Complex uplifting and faulting of the region, followed by extensive erosion, have created the present landscape.
Valley of Fire is Nevada's oldest and largest state park, dedicated in 1935. Ancient trees and early man are represented throughout the park by areas of petrified wood and 3,000 year-old Indian petroglyphs.
We hiked the White Domes and Fire Wave trails; both were simply breathtaking. Valley of Fire is up there among my favorite State/National Parks, not very far behind Arches NP and Bryce NP.
I simply cannot imagine how hot this place must be in the summer. It is only mid-March and some of us were seriously overheating. On the Fire Wave hike, JF and our friend helped an elderly man down a slippery sandstone path. He was hiking in this rough terrain by himself with his cane and no water, and we left him a bit concerned. On our way back, we stopped at the Visitor Center and JF let the rangers know about him. They took notes and said they would be there in about 30 minutes. I am always amazed at how sensitive JF is to others… He also made the girls and I drink a full bottle of water before heading back on the road to make sure we would not be dehydrated.
As we drove back to Vegas (there is no cell connexion in the Valley of Fire campground, by the way…), I put my sandy feet up on the dash of the Westy, rolled down the window so the wind would cool me down, and let all that beauty sink into my soul. What an amazing day we had!


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ETHNews had the opportunity to sit down with Ken Brook, CEO of VidRoll, to discuss how his team's new Ethereum blockchain initiative, adChain, is setting out to disrupt the world of online advertising by adding transparency and fairness to this opaque industry.
ETHNews: Your primary company is VidRoll. Can you tell us what VidRoll is and how it has led you to your new Ethereum initiative, adChain?
Ken Brook: VidRoll is a video advertising technology company and we work directly with content publishers to help them generate advertising revenue from their audiences and users. For example, if you have a website, blog, or mobile app, we provide the technology to generate revenue from video advertisements.
adChain is our blockchain initiative. Over time I've learned that the online advertising world is in a state of distress, and a lot of the challenges that we were facing day to day was something that we saw as an opportunity. So we began exploring new technologies to help fix or, at least, take on these challenges. We saw a clear path forward in terms of deploying and iterating blockchain technologies that layered on top of what we eventually settled on as the most suitable blockchain for our needs, which was Ethereum.
E: Can you talk a bit more about the challenges that online advertisers are facing today and why there is a need to explore solutions like Ethereum?
KB: Well fraud, in particular, is a major issue costing online advertisers an estimated 8.2 billion dollars per year. Much of this fraud is due to a lack of transparency. Also, when you compare the way our industry has evolved- it has been slow compared to the evolution of the internet as a whole. There are gaps in our industry that have formed and a lot of bad actors are exploiting these gaps. And as our industry becomes more centralized there are only a handful of companies that essentially monopolize the market. 85 cents of every dollar spent on online advertising goes to Facebook or Google.
When you think about it, a lot of the internet is powered by ad-supported media and in order to ensure premium content remains free, there needs to be this ad-supported model. But the current ad-supported model is imbalanced and definitely not transparent. Which takes us back to why we began exploring blockchain technologies in the beginning- as a way to plug in these gaps with the new technology and solve problems to make our industry more efficient.
E: 85 cents for every dollar spent going to Facebook and Google is a large percentage. Could Ethereum and the blockchain potentially stop that? And if so, how might adChain play a role in that?
KB: In my mind, it's not necessarily about stopping them, it's really just democratizing the access to content and not have to be forced to trust their algorithms and what is displayed to you on their network. When you look at it, as a centralized for-profit company that controls your data and the content you see, there is this element of trust that people forget about. When they go to Facebook they're checking news articles, their Facebook friends' pictures, and posts, but they don't think about the underlying algorithms that power everything that goes on behind the closed wall of Facebook.
You have these algorithms that are designed to maximize profit and it's not in the best interest of the user. If anything, it's exploiting the user's data and selling it to advertisers. This company is one of the most profitable companies in the world. Why is that? I feel like people don't ask that question enough. We should really look at how we're accessing content and what algorithms put that content in front of us. Where do these algorithms take us? If we just look at the content and believe it as truth and don't ask questions, it's a slippery slope that could lead to a scary future.
E: As discussed, Facebook and Google's revenue model is designed to leverage user data by selling it to advertisers. How will adChain's revenue model either resemble or differ from those other companies' revenue model?
KB: The difference between adChain's model and Facebook and Google is that Facebook and Google decide how much is paid out and how much to sell it for. They dictate their profit margins and it's usually at the expense of its users. Our model is about creating a healthy ecosystem that is balanced, market driven and that has a built in mechanism for self-sovereignty. The main difference on adChain is if you provide your data willingly to advertisers, then you as the individual are compensated fairly for that data based on market demand and free market mechanics.
Also, adChain is distributed and decentrally owned. But centralized around one source of truth, which is the Ethereum blockchain. The Facebook/Google model is that there is this data store that we are using that currently is being sold, but from centralized tech stacks and data stacks and they're siloed and you can't audit that. But what adChain is doing is acknowledging the fact that this is all first-party data and it should be owned by that party, and how it's sold is up to them. How much it's sold for is up to them. If there is demand for that data then it will be purchased and at what price is whatever the market decides. And those market mechanics is something that we don't control. Our (adChain's) algorithms that we write are not controlling that.
E: How will adChain's primary function on the Ethereum blockchain be defined?
KB: At a high level, the primary focus of our efforts is going to be the development of Dapps (decentralized applications) that will sit on top of adChain, which is essentially the platform. This foundation will address the fundamental issues of online advertising today. These Dapps that sit on top of adChain will make up the new online advertising ecosystem.
If you look at it like the spoke-hub distribution model, [which is a system of connections arranged like a wire wheel in which traffic moves along spokes connected to the hub in the center], adChain would be a spoke of the Ethereum hub. And that spoke is the platform Dapps are built on. But that second-order effect of Dapp development becomes enabled by the protocol layer. We will also be doing an Ad Token launch to standardize the means of exchange on the protocol.
Also, within adChain, reputation exists in a system that can't be doctored for the benefit of one in an unfair way. It allows us to be a participant in this online advertising ecosystem, but also as a developer. These new Dapps are what's going to drive the value and create a healthier ecosystem for the online advertising space.
E: Is adChain collaborating with any other players within the Ethereum community?
KB: Yes, currently we are working with ConsenSys utilizing several of their projects, one of which is called uPort. We're leveraging uPort for our identity solution. Part of our development roadmap is piecing together other projects that exist, or are currently being developed, to ensure that we have the best possible solution. Since the problems we are tackling are vast, we need to focus on bringing in the best for each component, and you can't do that with just one team or one project. That is what I really love about the Ethereum community. Over the last year, we've met and collaborated with some amazing teams. Being able to come together to accomplish a shared goal is pretty awesome. I've met some of the most intelligent people ever, that are working on some of these projects, and that's magnetic. We're working on a lot of different problems and are going to need to lean on the community to solve them.
E: Ethereum definitely is a magnetic project. And there is a lot of speculation about what the major draw for widespread adoption will be. How do you see things playing out? Will it be a slow and steady pace of adoption or over a lengthy amount of time? Or do you think a killer Dapp will emerge onto the scene that will transform public opinion overnight?
KB: From my perspective, I don't think it's going to be a slow boil, but I also don't think it's going to be this abrupt revolution. I think adoption will occur somewhat unknowingly to the general public. I think it's slowly going to integrate into the mainstream systems and I think users may likely find themselves using an interface that leverages Ethereum technologies, Dapps, or other protocols without them even knowing what the blockchain is. I think adoption can still be achieved without being on the front page of the Sunday news. But I think by that time, Ethereum will have gained widespread traction and the applications will be far reaching. Once local developer communities- here in L.A for example- once they start to actively participate in projects, write smart contracts, and build out Dapps, that's when you're going to see this shared mindset and explosive growth for Ethereum. But I think in the future a lot of people will be using applications with underlying blockchain technologies and they won't even know it.
E: What is the current timeline for adChain's implementation?
KB: Right now we are still in development. But we are looking to start releasing in January 2017 and showcasing the scalability and value that adChain's specific implementation brings to the online advertising space.
E: Fantastic, we look forward to it! Lastly, if you made a prediction about what online advertising will look like in ten years, what would it be?
KB: Wow, ten years… That seems like a lifetime. That depends on a lot of things. But one thing I'm certain of is that if nothing changes over the next ten years, then the future of online advertising will be a scary place. And I think if things don't change fundamentally, the government will step in to regulate because centralization and fraud are becoming such an issue.
If I were to be optimistic about the future, and knowing what we are doing with adChain, I'm hopeful that we are going to change the industry. Once we have adoption and the industry welcomes this new utility, then it's a matter of how we approach the development of value.
If we can provide the opportunity for an independent entity to operate in a healthy, online advertising ecosystem, that adds value to the supply chain instead of just extraction. Then over time we will have an emerging ecosystem of Dapps that de-incentivizes fraud and malicious intent and gives value back. This virtuous value exchange is what I hope the industry looks like in ten years.
ETHNews will be following adChain as it releases more information about its protocol in January of 2017. Stay tuned for a follow-up story once more development and adoption surfaces about this cutting edge project.


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Pink and lilac, pop up play tent from the Disney Princess collection. With turretts, flags, window and drop down door, this is sure to be a hit with your toddler.
A choice of two designs - Jewels pretty pink with diamond encrusted turrets, and Sparkles deep pink and purple turrets.
Size: 75 x 75 x 110 cm
Material: Fabric


text: "AVATAR" has returned from a Middle East tour, where the Oscar favorite was screened for thousands of troops. Director James Cameron and cast members Sigourney Weaver, Stephen Lang and Michelle Rodriguez traveled to Bahrain in late January to show the movie at a military base and aboard USS Dwight D. Eisenhower and USS Bonhomme Richard. James' brother, John D. Cameron, a former Marine and a military consultant on the picture, told us: "Showing 'Avatar' to the troops was truly a once-in-a-lifetime experience. To do something for the men and women who serve our country was a great privilege."


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Special Events/Fellowship/Social
Auction Committee
The Spring for Success Dinner and Auction Gala is held in April to raise funds for faith community. Previously held at Brookfield Country Club, volunteers are needed to organize the event, recruit sponsors and solicit item donations.
The church sponsors many functions that need desserts or finger foods. Volunteers will be called upon once or twice a year to bake or cook.
Card Players
This group meets the third Friday of every month from 1:30 p.m. to 4:30 p.m. in the Parish Center. Meetings include card playing, refreshments and fellowship.
Coffee and Donut Social
Offered monthly following Sunday Masses to encourage fellowship among parishioners. Facilitated by various parish ministry volunteers.
Picnic Committee
St. Mary's Church picnic is held the second last Sunday in July. It is the major fundraiser for the parish and requires the hands of all parishioners. Volunteers help with picnic planning, set-up, clean-up and working food and game booths.
Chowder Chase 5K
Volunteers are always needed to assist with the 5k Chowder Chase and Beer and Wine Social held the Friday night of picnic weekend.
Forever Young (55 & older)
This senior organization is for anyone 55 years of age and older. This social group hosts monthly events including speakers, outings and social gatherings.
Quilting group meets in the cafeteria on the second Saturday of each month from 10 a.m. to 2 p.m. Afghan size or larger quilts are made to gift to those in need. Anyone is welcome to join – all that is required is a willingness to learn. Donations of fabric and sewing supplies are always appreciated.
Soup Supper/Friendship Supper
Volunteers are always welcome. The Friendship Supper is a pot luck dinner on Holy Thursday before the evening Mass. The Soup Supper is a family event held during Lent.


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Although Tropical Storm Irene's winds and rain over the weekend caused power outages and felled tree limbs throughout the region, the storm's punch on the Seacoast was far from the knockout many anticipated.
Although Tropical Storm Irene's winds and rain over the weekend caused power outages and felled tree limbs throughout the region, the storm's punch on the Seacoast was far from the knockout many anticipated.
Much of that outcome, of course, was due to the storm's track, which veered inland, largely sparing the Seacoast but leveling an uncompromising blow to our neighbors in central and western Maine and New Hampshire and the state of Vermont.
But we as well believe residents' and officials' preparedness for the storm contributed to its less-than-catastrophic impact. To date in our region, no loss of life has been reported here due to Irene and local officials say the property damage wrought by the storm has been contained. Aside from a handful of boats that either capsized or ran aground, there were no maritime-related incidents or injuries, either, officials said.
It would appear the storms of our past — notably the ice storm of 2008 — have taught us well.
Forecasters were on Irene early, chronicling its march up the Eastern Seaboard last week. State leaders took note, as on Friday, Gov. John Lynch in New Hampshire and Gov. Paul LePage in Maine were among a handful of governors who called a state of emergency for their respective states. From there, a trickle-down effect took hold, as utility and cable television providers marshaled their crews and called in others to respond to any anticipated disruptions in service. Meanwhile, town officials and first responders across the Seacoast met early and often to discuss emergency-response plans. Residents, too, knew what to do, clearing out store shelves of the essentials: water, milk, bread and batteries.
Sure, Irene has created problems: Schools in SAU 21, SAU 16 and in Newmarket were closed Monday and thousands remained without power. But emergency shelters opened by officials in Hampton and Seabrook had no takers, while only six individuals checked into the Exeter-area shelter at Exeter High School. In South Berwick, Maine, the emergency center at Marshwood High School closed Monday. In Portsmouth, Fire Chief Chris LeClaire reported a "very slow day" on Sunday, and the city's emergency operations center closed early.
All of this is good news and speaks to residents' and officials' effectiveness in dealing with this storm.
"I will pre-plan like this every time now, because the more we do ahead of time, the less we have to do afterward," said Hampton Falls Fire Chief Jay Lord, in assessing his department's efforts to prepare for the storm's impact.
The lessons learned through Irene will undoubtedly serve us well in the future.


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Charity Name:
Habitat for Humanity of Metro Denver
CFC Number:
Cause Area:
Charity Type:
Narrator: "What does it look like when a life is truly changed?" Female Speaker 1: "I feel a sense of accomplishment because I built a house. This house has brought us financial independence." Male Speaker 1: "It's a great place to raise a family." Background: Workers helping one another *cheering, high-fives, laughing* Female Speaker 2: "Strength" Female Speaker 3: "Fuerza" Female Speaker 4: "When I look back from where we've come from to where we are today, it makes my heart very happy." Male Speaker 2: "Potential" Male Speaker 3: 'Potencial" Female Speaker 5: "For me this house means all of us together." Female Speaker 6: Sniffle* "I'm sorry" Male Speaker 4: "Security" Female Speaker 7: "Security" Male Speaker 5: "Every family dreams to have their own house. This house changed our lives." Narrator: "Habitat for Humanity is at work in metro Denver and around the world. Through housing we empower."


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Advanced Analytics & Visualization
Analysis and exploitation capabilities.
RemoteView™ Extensions
Expand the power of RemoteView through one of the highly-capable product extensions.
Enhanced Analytics
Take imagery analysis one step further with a suite of products that can work alongside the classic RemoteView offering.
Sensing and Image Processing
Maximize your awareness, knowledge and insights with Textron Systems' real-time spectral imaging and imagery analytics tools. From instant hyperspectral image processing to EO/IR video exploitation, Textron Systems can empower you to leverage image-based information for immediate action.


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2017 Lasker Award
Dir. Flora Lichtman
A short documentary about Michael Hall, winner of the 2017 prize for basic medical research for discovering how a group of proteins called target of rapamycin (TOR) direct cell growth.
Omega House Hospice
Dir. Daniel Cowen
A short film about students volunteering at an AIDS hospice in Houston, TX.
Music at Central
Short promo for Central Synagogue showing their integration of music and worship.


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Kinsta Managed Hosting Review: Blazingly Fast and Solid Features
Kinsta is a relative new-comer to the WordPress managed hosting scene, but since launching in 2013 has quickly become a force to be reckoned with.
Marketed as "Better, faster, stronger managed WordPress hosting," the web host uses Google's Cloud Platform to provide fast speeds from the web giants secure and reliable data centers, paired with Kinsta's simple and intuitive hosting panel.
We get asked all the time for web hosting recommendations and do our best to point members in the right direction, but who you go with ultimately comes down to your site's needs – and also how much you're willing to spend.
To help make the decision a bit easier, we've put some of the biggest WordPress managed hosts to the test, with a focus on customer experience. There are already plenty of reviews out there that look at speed and stability, but the ease of use and support capabilities of a company are just as – if not more – important because you'll run into trouble sooner or later and a great host will always go above and beyond to help you out when disaster hits.
With all that in mind, this is the fifth of eight reviews, this time putting Kinsta to the test.
Check out the other posts in this managed WordPress hosting reviews series:
- WP Engine Managed Hosting Review: Feature-Packed and Hard to Fault
- SiteGround Managed Hosting Review: Excellent Support, Not Really for WordPress
- Flywheel Managed WordPress Hosting Review: Beautiful, Functional Solution for Designers
- Pagely Managed WordPress Hosting Review: Solid Service, Shaky Communication
- GoDaddy Managed WordPress Hosting Review: Budget Hosting, Poor Features
- Kinsta Managed Hosting Review: Blazingly Fast and Solid Features
Kinsta: Company History
Kinsta was built by developers who worked with WordPress clients and after becoming more and more frustrated with the available hosting options, they created their own beta service in 2013, before officially opening their offices in 2014.
In two years they have tripled in size, following the strategy of using the most modern available technology available – something that their small size (their CEO helps answer support tickets) makes a lot easier.
First Impressions
My first impressions put Kinsta somewhere in the middle of what's starting to become a crowd managed WordPress hosting space. I like the boldness of the opening section of its website and the images used, but I don't like the fact that there is a CTA to the contact page instead of a link to the registration page – even though the page exists.
That aside, one of the biggest pros is that the pricing is super-clear and Kinsta offers a lot of flexibility when it comes to scaling plans, which I'll go into more detail later. One of the cons, however, is that there isn't a lot of information about what users are buying. For example, while I found information about the stack used (Ubuntu, PHP 7, MariaDb, etc.) I couldn't find any hardware specifications. Kinsta uses Google Cloud so they are definitely using their machines, but you don't know the exact configuration.
Just like with our Flywheel review, time to contact support…
After some discussion, I found out that the machines are constrained to 2-6 CPUs per VPS, but they allow the container to scale to 32 CPU when there is a surge. These machines have 208GB RAM, which is allocated dynamically as needed. The support team member was very helpful – I'll talk about more support below.
Plans and Pricing
Kinsta offers eight plans in addition to a possible custom solution if you need anything out of the ordinary.
The web host is one of the most expensive solutions available with its account coming in at $100 per month.
Kinsta offers $200, $300, $400, $600, $900, $1,200 and $1,500 per month accounts. The equation is pretty simple: The more you pay, the more resources you get. It's all laid out very clearly and I particularly liked the rounded pricing. No ".99" and no "until your first renewal" price discounts.
What I love about Kinsta's pricing is that I am a big fan of the bandwidth-based model. It seems unfair to me to penalize someone for a popular site (billing based on visitors), especially since visitors alone don't cost the host anything. It's bandwidth that incurs the cost, so passing that on seems the most straightforward route to me.
That said, you may want to pause to think before choosing a host. If you have a video streaming website it may be better to go with unmetered bandwidth. But if you have a lightweight site I'd recommend bandwidth-based billing instead.
Getting Started
According to Kinsta's support team, the web host is in the process of creating a new admin interface, which will feature better content for new visitors. But until it's released, buttons take you to the contact form where you can speak with a member of the team. That said, you can register for yourself, and once you do you can take a look at the admin interface.
To get going with a site your first order of business is to add a payment method and grab a plan. This can be done in the billing section. It would be better if there was a wizard or some sort of direction, but the process is straightforward enough.
Once you are past this point, creating sites is extremely easy. Go to Sites, and click the Add New button. This was the first place where I really started liking Kinsta. The form is easy to understand and includes some features not available elsewhere. It doesn't allow you to use "admin" as your username (it must be eight characters long) and forces you to create a strong password – yay security! It allows you to choose a language other than English right off the bat and sets up Multisite or WooCommerce for you if you need them.
After a few seconds your new site will be created and assigned a temporary URL you can use to set things up. You can then add your own domains at any time and use the DNS management to set everything up as needed.
Ease of Use
The experience of the Kinsta dashboard doesn't come close to Flywheel's, which I really love. However, it does do a good job of giving you the tools you need – which is the most important thing – even if it doesn't look as polished. Once you spend some time using Kinsta, though, you'll appreciate some of the little things on offer.
One of my favorites is the SSH access display. You use the following method to SSH into a server:
ssh [email protected] -p port. That's three separate things, in addition to the password. SSH details are the most common things I look up and Kinsta doesn't just have the information but the full code to SSH into the server right there on the site details page. Useful!
Another section where ease of use has been put front-and-center is the Backups tab. Due to the container-based system Kinsta uses, backups can be performed using snapshots. This means that backups are almost instantaneous – no more waiting around for the process to complete. Backups show up after a few seconds and can be restored at any time.
Note: Restoration time takes just as long as anywhere else. A nice touch I've noticed is that a backup is created whenever you restore a backup, just in case you need to go back and undo the restore.
The bottom line is that while I'm no fan of the design, the power and ease of use is there, which is what really counts when using your hosting service.
Since Kinsta is a managed WordPress host proper, features that make it stand out from the regular crowd are expected – and delivered. I've mentioned some of them already, but here's a more extensive list:
- Free migrations
- Instant manual backups
- Automated daily backups
- 3 global locations per site
- Cache flushing
- Live and development environments
- Cache, backups and other features available in the development environment
- PHP Version switcher (5.6 and 7)
- Switch to HHVM from the dashboard
- PHP/HHVM Restart
- Manage SSL certificates
- Analytics
- Migration requests available from the dashboard
- Built in DNS management (uses Amazon Route 53 in the background)
- SSH access
- WP-CLI support out-of-the-box
- Two-factor Authentication support
- Basic collaborators
The list is surprisingly extensive considering that Kinsta hasn't been around as long as some of the larger companies, like WP Engine or Pagely. I love how easy SSH access is and that I have WP-CLI at my fingertips. I also use the DNS management tool a lot and enjoy the speed boost that the server architecture provides.
As with Flywheel, you can manage your SSL certificates but not buy them. I would also love to be able to switch off caching altogether. I can flush it anytime and the site is uncached when logged in but for some tests it just makes sense to sidestep the cache completely. Support can do it for you buy a button would be nice.
Environment switching could also be a bit more obvious. I had to look hard to find it at the top of the site details page.
While Kinsta does allow you to give others access to your account it's very basic at this time, and certainly not as refined as Flywheel's system, which focuses on it a lot more.
Another omission is Git support. You can use Git through your SSH access, of course, but there is no Git-driven workflow as you might find at Pantheon or WP Engine.
Overall, I think Kinsta has a fantastic feature-set. Technically, the web host seems to be at least at the level of the older companies, like WPEngine, Pagely and Pantheon, even surpassing them in some cases.
My experiences contacting the support team were excellent. I received detailed and honest answers to all of my questions. When I enquired about their hardware I didn't expect an answer like this:
"We use Google Compute Engine servers, which ensure high speed and automatic scalability which means that instead of being constrained to 2-6 CPUs per VPS as with other providers we actually let the site's container to scale to as many CPUs as needed when there's a surge, and for load balanced clients an infinite number of CPUs as our system dynamically spins up more machines and scales back when the traffic wave subsides."
I tried to quiz them with some common WordPress related site issues and got all the right answers, so top marks!
Kinsta uses a ticket-based support system via Intercom. It feels like a real-time chat but in the background it isn't. I got a response within 5 minutes when I tried to talk to them a 3pm. I also tried at 5am (I happened to be up early while writing) and got an answer within 3 minutes. I may have just picked two low-support times by chance but impressive nonetheless!
As with all the reviews in this series, conducted comprehensive speed tests. Despite what some may say, any test you run is highly subjective. Your site may be on a faulty box – perhaps the only fault out of hundreds – your local connection may be unstable, the software you use to run tests might have had a rough day, who knows.
I installed three websites:
- Vanilla Twenty Fifteen theme filled with demo content – 1.49Mb, 53 requests
- WooCommerce shop running on Twenty Fifteen, Shop Page – 0.479Mb, 55 requests
- Out of the box Avada installation using the Cafe demo – 24.3Mb, 134 requests
When uncached, the vanilla Twenty Fifteen site loaded in a staggering 983 milliseconds, the WooCommerce shop loaded in around 780 milliseconds, and the Avada demo loaded in 7.1 seconds.
When cached, vanilla Twenty Fifteen loaded in around 800 milliseconds, the WooCommerce shop took about 700 milliseconds, and the Avada Cafe demo clocked in at 3.1 seconds.
Again, these are casual tests and may not reflect your experience with Kinsta, keep in mind that website speed has so many factors it is difficult to accurately gauge it on a company-wide level.
Disclaimer: In putting together this review, we bought our Kinsta review account just like any other customer – via the sign-up link on the homepage. We didn't let Kinsta in on the fact we were reviewing their services to avoid any special treatment.
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The Good
- Blazingly fast
- SSH and WP-CLI out of the box
- Instant backups
- Focused on speed and dependability
- You can choose a datacenter for each site
- Free SSL certificates (which is slowly becoming the norm for web hosts)
The Bad
- No Git deployment
- Dashboard could use some spit and polish
- Highest entry level pricing
Stay tuned for the final article in this series coming soon, which will compare all eight web hosts side-by-side to decide which one is best.


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This is a really basic face that I usually do better but I wasn't feeling terribly good when I filmed. I apologise for the sniffling!
Rimmel Lasting Finish 25 Hour foundation in 100 Ivory - £6.99
Stargazer pressed white powder - £3.99
MUA matte black mono eyeshadow - £1
Bourjois Kohl & Contour 16h eyeliner pencil in Noir Expert - £2.99 from cheapsmells.com
Angled brush - £1
N.Y.C. Liquid Lipstick in 438A Betti Ann - £1
Total: £16.97
I did this one by raiding my own stash and checking receipts/shops/site where I originally bought the products for prices.


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Copenhagen Plant Science Centre PhD Summer Course
Synthetic biology is the engineering of biology: the deliberate (re)design and construction of novel biological and biologically based parts, devices and systems to perform new functions for useful purposes, that draws on principles elucidated from biology and engineering.
In this context prokaryotic and eukaryotic organisms like bacteria (e.g. B. subtilis or E.coli), yeast, microalgae or plants are interesting since they hold the promise for truly sustainable production of high-value compounds like pharmaceutical, commodity chemicals or even fuels. Traditionally the organisms of choice for synthetic biology have been E. coli and yeast. However, in the future synthetic biology in plant science will have a great potential both for redirecting and engineering of new biosynthetic pathways as well as for improving yield of our crop plants. In this field, the University of Copenhagen is among the leading institutions.
Scientific content
- Choice of organisms (chassis): (cyano-) bacteria (B. subtilis, E.coli, Synechocystis), yeast, algae, higher plants (chloroplasts).
- The parts: Promoters for regulated expression, transcript and protein stabilization and modifications, vectors, neutral integration, DNA synthesis, flip elements for on-off gene expression regulation.
- Cloning and high-through-put methodologies: cloning methods, gene stacking, gene replacements.
- Bioreactors: types (closed, open ponds, etc.), designs of growth regimes (continuous versus batch), harvesting methods and product recovery.
- Downstream processing: product extraction, stabilization and quality control
- Ethics in synthetic biology.
- Safety and regulations.
- Intellectual property rights (IPR)
Price: 1500 DKK. Lunch and coffee/tea is included.
Registration: To register for the course please fill in the registration form and send to Lene Rasmussen email@example.com


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Are smoking bans going too far? Are your constitutional rights being violated? The Wall Street Journal Law Blog's Appeals Court Rejects Challenge to outdoor Smoking Ban written by Joe Palazzolo reported on a 2011 case filed in Clayton, MO by Arhtur Gallagher. Mr. Gallagher has been an avid outdoor smoker for many years and felt that his constitutional rights were being violated by the outdoor smoking ban in city parks that had been imposed by Clayton.
On Thursday, the St. Louis-based U.S. Court of Appeals for the Eighth Circuit failed to recognize a right to smoke and held that Clayton had a rational basis to restrict smoking in parks — namely, to preserve and protect the health, safety and welfare of the public. In an opinion issued by Chief Judge William Riley of the Eighth Circuit, the judge cited a report issued by the U.S. Surgeon General which stated: "there is no risk-free level of exposure to secondhand smoke". Clayton had relied on this and other studies when passing the outdoor public smoking ban in city parks.
While Mr. Gallagher had argued that the ordinance unfairly targeted smokers, he failed to address other sources of air pollution, such as smoke from barbeques or exhaust from nearby vehicles. He also argued that no member of the public could be harmed by secondhand smoke outdoors, because it dissipates in the air.
As you are wrestling with the constitutional fairness of the recent Eight Circuit Court decision, it's important to weigh the potential impact that secondary smoke could have on other children and adults who are in the park. We thought that the YouTube video below will help you evaluate these risks.


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Water, a major challenge
Nutrition and health above all is at the heart of our mission.
Food security and livelihoods for all.
We provide psychological support to the most vulnerable
Mobilise and influence
Faced with the accelerating trend in global warming, natural disasters are more frequent and more intense.
We are developing research programmes in response to the problem of hunger in the world.
The malnutrition of one out of two infants is linked to waterborne diseases, to an unhealthy environment, and limited access to drinking water. In 2016, 1.8 billion people used water coming from a contaminated source.
More than 80% of the water used generated in the world goes back into the ecosystem without being treated or recycled. In the majority of cases, the community does not have the infrastructure required for treating used water.
Water is draining from fecal matter, medical waste, farming pesticides and potentially-toxic chemical products discarded by human activity. Entire communities can fall ill if the drinking water is contaminated and hygiene is neglected. On drinking a water source contaminated by excrements, the people risk catching fatal illnesses such as diarrhea, cholera, dysentery, typhoid or polio.
Action Against Hunger (AAH) intervenes in the prevention of malnutrition and leads programs for improving the access to clean water, building latrines, drainage, etc. It also holds awareness sessions on good hygiene practice and water management. In emergency situations (epidemics, natural catastrophes, etc.), they put an activity leader out in the field (distributing water with tankers, hygiene kits, putting into place emergency sanitation, risk prevention programs) whilst at the same time coordinating the humanitarian response.
In addition to treating and preventing malnutrition, AAH follows an integrated approach to managing the risks related to natural catastrophes by adapting to climatic change. This cross-transversal approach is integrated in their programs in different operational interventions. This involves preparing for implementing strategies and practices aimed at limiting the vulnerability of the people, the risks and the consequences of the catastrophes on the lifestyle of the people.
The lack of access to drinking water, sanitation, and hygiene and their consequence on malnutrition are the biggest challenges on a global scale that we are trying to overcome.
Position & policy papers, studies, manuals & guidelines, reports
The latest news about our Action.
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The 6 Phases of Ophthalmic Preclinical Research
The outcome of a clinical research program depends, in no-small part, on the decisions made during the preclinical phases of development. As with virtually all fields of pharmaceutical research, the goal of the ophthalmic preclinical process is to identify and elevate a lead candidate to advance into the next phases of research, or to eliminate a candidate in the research stage as early as possible to optimize R&D resources and efforts.
Since animal models can reproduce important pathologic aspects of human ocular diseases, they're used in preclinical research to determine the efficacy of the novel therapies.
Those developing such therapies, however, should be well aware of important limitations associated with animal models. While it's possible to model some parts of a human disease in a non-human species, many ophthalmic conditions – particularly those affecting the posterior segment – could present challenges for researchers.
To meet these challenges, EyeKor's EXCELSIOR™ Preclinical platform gives researchers more power to see valuable results from their preclinical data. To set the stage for how these new systems can help, let's briefly step back and run through each phase of the ophthalmic preclinical process step-by-step.
1. Initial Discovery & Formulation
Discovery of potential candidate therapies is the first step toward developing them into novel drugs. With most ophthalmic diseases, this typically begins with target identification, or selecting the particular pathogenesis mechanism of the disease that affects the part of the eye one intends to treat.
Target identification for ophthalmic preclinical trials can be carried out a number of ways; but most studies use in vitro enzymatic assays or binding and cell-based studies. Common tools used for these initial preclinical stages include mass spectroscopy and liquid chromatography. After these studies are reviewed, researchers can confirm (or refute) an interaction and choose a lead compound based on their findings.
Compounds that perform well in preliminary tests move into in vivo pharmacokinetic and efficacy studies for further evaluation.
2. Drug Metabolism and Pharmacokinetics (DMPK)
Once a lead compound is identified, researchers must then develop a drug formulation and delivery route that is capable of been administered in vivo, as investigated through Drug Metabolism studies. In ophthalmic drug development, this is often a challenging task as it requires researchers and study teams to consider many factors that may influence the results of preclinical studies or clinical trials.
Pharmacokinetic studies of ophthalmic drugs provide developers with important data for determination of both optimal dose and frequency of administration. These studies also provide a number of other key data points, including:
- The maximum concentration of the drug inside specific ocular structures, like the retina (Cmax)
- When Cmax is reached (Tmax)
- How the body affects the characteristics of the drug
A strong PK study may facilitate "screening out" of many candidates that have made it to this level of testing. In today's pharmaceutical landscape, therefore, researchers and study teams are conducting PK studies earlier and earlier to improve the selection process sooner.
3. Proof-of-Concept Studies
Proof-of-concept studies may have several goals, but among the most important is determining if the drug candidate exhibits expected results in a selected animal model, depending on known pathology and the drug's mechanism of action. For ocular drug development, these studies involve testing animals in vivo and typically use multiple diagnostic imaging procedures. Imaging biomarkers, derived from the results of the imaging procedures through carefully planned imaging protocol and post-acquisition data analysis, are used to capture the treatment effects throughout the course of the studies.
Ultimately, the results of the preclinical study should reflect what will be tested in humans during the clinical trial.
Clinical success is never assured, no matter how well a study is designed or conducted, and translatability between animal models and human patients is complicated by numerous factors However, better decision-making early in the development process, can maximize the predictive value of of preclinical results if moving forward into clinical trials.
4. GLP Toxicity Studies
Before moving into the next phase of preclinical development, manufacturers must first carry out GLP toxicity studies to the satisfaction of the FDA's regulatory guidelines. It's important to note that GLP toxicity studies will need to adhere to Good Laboratory Practices (GLP). Conducting animal toxicity studies to this quality system ensures study data is collected correctly and enough animals are tested to ensure the drug is both reasonably safe and effective.
GLP toxicity studies from at least two different species need to be conducted. Using similar imaging biomarkers to those used in proof-of-concept studies, and ultimately those will be used during the clinical trial stage, these studies are done to evaluate the treatments effectiveness in animal models.
EyeKor's EXCELSIOR™ Preclinical platform shines in the proof-of-concept and toxicology studies steps––allowing researchers to gather, manage and interpret imaging data in concordance with the information gathered at earlier stages.
5. CMC Efforts
CMC efforts (chemistry, manufacturing and control), represent the first phase of IND-enabling studies. When a final formulation for clinical use is prepared, these efforts ensure that the product is stable, and that the production process is both scalable and achievable within GMP standards.
6. Submitting IND Application
After compiling preclinical results, it's time to present findings to the FDA in both pre-IND and subsequent IND meetings.
The ultimate goal of these meetings is to design the clinical trial protocols based on the data gathered during every step of the preclinical process as they relate to dosage, frequency of administration and safety.
Perhaps the most important takeaway to remember when planning and carrying out the preclinical investigation process is to keep the final result in mind at all times. Don't make short-term decisions. Instead, consider the entire development process and put all necessary quality control measures in place well ahead of time.
Are you looking to bridge the gap between a preclinical and clinical program for your new treatment? EyeKor's EXCELSIOR™ Preclinical platform is a first-of-its kind FDA 501(k)-cleared, cloud-based software platform revolutionizing the way ophthalmic imaging data in preclinical investigations is managed.
This customizable software is designed to help your team manage the full spectrum of preclinical study types and imaging modalities, harmonize findings with ophthalmic examination data, gather reports in real-time and receive seamless access to expert analysis. Contact our team today to learn how we can help you make more informed decisions during your preclinical research.


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"Some people are always grumbling because roses have thorns; I am thankful that thorns have roses."
Monday Musings {29} - Anon
3 comments:
I love the positive thought part!ReplyDelete
OOPS sorry on my link - link is correct, I just forgot to erase the top words from Mr Linky
That is a good way to look at life...always think positive.ReplyDelete
Ahhh, the whole glass is half full/empty thing. Personally, I am a 'mostly full kind of gal (in so many ways, lol!).ReplyDelete
Happy Monday, been thinking about ya!
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