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This week, one of subscribers, which we shall nickname Tim, sent us a rather interesting email about his close shave with falling prey to an online fraud scheme.
Tim is based in Singapore, and was engaged in an online transaction through the popular online marketplace, Carousell. His account of what happened next makes for a pretty intriguing story, and is something Tim wants "the general public to be wary" and cognizant about.
His close encounter with a "cleverly planned" fraud across multiple mediums shows just how far people will go just to rip others off. Thankfully, Tim's quick-wittedness saved him from loosing a beautiful timepiece to a shameless invertebrate who was apparently inept in even crafting an email.
With material evidence courtesy of Tim, we delightfully expose a dumb fraudster's attempt at daylight robbery. The sensitive details of all persons (excluding the fraudster's) have been concealed to protect their identities.
Most of us reading this would have probably made an online purchase or sale before. In today's highly globalized world, a good portion of financial transactions occur online between buyers and sellers who have and will never meet each other in person. The advent of technology has only fastened the stranglehold e-commerce has on traditional brick and mortar businesses.
As with all things on Earth, there are downsides to every upside innovation brings. In the case of information technology, inter-connectivity brings with it the esoterica associated with instant gratification - a syndrome which most if not all of modern society has.
That addictive feel-good sensation of being replied and being able to reply to instant messages, or receiving instant notifications on updates to our social media shenanigans, or the ability to share stuff with our friends with a few key strokes has led to the gravitation of human activity in cyberspace.
More and more of our daily lives are now spent online. We make "friends" with people whom we may never meet because we still feel safe behind the anonymity our social avatars gives us. However, we sometimes unknowingly expose ourselves to the uncanny and treacherous nuances which can cause real and material detriment to ourselves and people around us.
Online marketplaces are one of such examples where countless cases of fraud occur each day. In most cases, buyers are the usually the victims of these crimes. It was the opposite in Tim's case as you will read.
Caveat emptor literally applies here, "let the buyer beware".
A sprawling global app development industry means that there are always new avenues for buyers, sellers, customers, and merchants to casually do business; and for online fraud to occur.
Most of these online marketplaces are loosely regulated if at all, making it inherently unsafe to transact through online payments.
Based on the information Tim provided us, we will now walk readers through his experience and ultimate realization that all could actually have gone pear shaped.
It started on the 27th May, this past Wednesday, when Tim decided to list one of his watches, a particular chronograph which he previously purchased for more than S$1,000, on the popular online peer-to-peer marketplace called Carousell.
Carousell is a Singapore-based startup founded a few years ago; it has user bases across multiple countries including Malaysia, the UK, and America, but its primary market is Singapore and Malaysia. Carousell is primarily available through mobile applications which allows sellers to list items they wish to sell, and allows shoppers to communicate with sellers.
The application does not support integrated payment systems; buyers and sellers have to transact through a mutually agreeable medium - cash, bank transfer et al. The market place is generally unregulated with both buyers and sellers encouraged to conduct due diligence before transacting.
A day after listing his watch, a prospective buyer going by the user name "american_puppet" engaged Tim in a private chat through the application.
Tim provided us with the entire chat history which readers can view throughout this article. Tim told us that his only correspondence with that prospective buyer was exclusively through the application's private chat function.
"american_puppet" contacted Tim slightly after 3am (SGT) on Thursday (28th May). The conversation had a seemingly ordinary beginning with the prospective buyer asking if the timepiece was still on sale. The chat progress on as the prospective buyer asks Tim if he has any other gadgets on sale.
Tim made known to us that he had multiple listings of the same watch, a common tactic used on Carousell for sellers to reach a large audience.
Similar pictures of the watch were used in each listing, but the prospective buyer was unable to recognize that they were actually of the same watch - a crude giveaway that the buyer does not have an inkling about what 'she' was wanted to purchase.
During the wee hours of Friday morning, the prospective buyer messages Tim, saying that 'she' was interested in buying the watch for 'her' son who was "schooling in malaysia".
'She' makes an unusual request for Tim to ship the watch to 'her' son in Malaysia. Tim told us that he did was not yet suspicious at that moment.
Assuming that the prospective buyer was in Singapore, Tim invited 'her' to view the timepiece. He was the told that the prospective buyer was not in Singapore but in America on a vacation.
'She' claims that America is 'her' homeland. Another giveaway - Americans do not typically speak or type in the manner "american_puppet" did; the dots just do not connect. Tim was still not suspicions at this stage.
Tim implied that he was willing to ship the watch to Malaysia by offering to use a courier service. Things began to change notable after Tim's implied willingness to secure a deal.
We noticed that the prospective buyer then began to steer the conversation; suggestive behavior like recommending which courier service to use, asking if they could take the chat to a direct messaging service, and acting impatient - telltale signs that the prospective buyer was well organized.
The conversation resumes on Friday afternoon when the prospective buyer pesters Tim to hasten the deal, claiming that 'her' son's birthday was on Saturday and that 'she' needed the watch to be shipped out on Friday. Another red flag for us - using the pressure of time to influence the outcome of a deal.
Tim proceeds to request for a PayPal payment to his account before he can arrange for a shipment to be made. The prospective buyer strongly recommends Tim used Fedex and a particular shipping methods. 'She' even knows the approximate cost of the shipment - another reason to be suspicious. Tim admits that up till then, he has still not smelt a rat.
"american_puppet" then asks Tim for his email address registered under his PayPal account. Tim provides 'her' with his email address and then confirms what he will be including in the package that he will ship out once his PayPal account has been credited with the funds.
We note that there were absolutely no price bargaining on the part of the prospective buyer. In our knowledge, users of Carousell usually make concessions and haggle over the initial offers of listed items, especially so for higher prices items such as the watch Tim had listed. This should have raised an eyebrow or two.
At 304pm Friday afternoon"american_puppet" messaged Tim with an image of the alleged PayPal-generated receipt for the online payment of US$560 to Tim's account.
Tim notes that the image was in a low resolution and suffered from severe color degradation.
"There were reddish and bluish outlines around the black wordings. It was like the image was screen captured many times and then compressed into a format to save space, and then uploaded onto social media and then only sent to me." A pretty incredible description, and definitely not something we would associate with legitimacy.
Shortly after, Tim proceeds to check both his email inbox and monitored his PayPal account for notifications if a payment had been made to his account. In the next couple of hours, he had received no notifications from PayPal that money was credited to his account. Tim ensured us that his PayPal account was verified and he was able to receive payments without restrictions.
Despite repeated interrogations by the buyer, Tim maintained his composure and cross checked with PayPal's support forum and its FAQ section for advice regarding payments. He told us that if a payment was made through a person's PayPal balance or an approved credit card that was linked to a payor's PayPal account, the payee's account would be credited instantly without delays.
Referring to the chat history, and in particular the buyer's reply that it "might take a few hours" for the funds to reach Tim's account, Tim told us that he started to become apprehensive about the entire legitimacy of the alleged transaction.
Note also that the buyer's tone had taken on the impression of fluster, regularly sending Tim messages insisting that he had been notified by PayPal when there was apparently no new messages in his inbox.
The buyer even prompted Tim to check his "mail folders", implying that PayPal's email might have been shuffled into spam or junk boxes - something that almost never happens because all legitimate emails from PayPal bear a unique hidden signature which Google (Gmail) recognizes as secure; secure emails will never automatically be moved to junk or spam boxes.
Tim told us that when the buyer said "why are you behaving this way", he really started to take the "entire thing as a joke", but "never made it obvious" to the buyer.
Our analysis of the snafu thus far tells us that the buyer was trying hard to put on a genuine show of urgency and confusion, something that backfired almost immediately.
Tim displayed professionalism when he reiterated that he would not send out the package until he received direct confirmation of the payment from PayPal themselves. When he made that hardlined statement, the buyer retorted rudely with "hey" and "paypal notified you". Tim then asked the buyer if 'her' bank had sent 'her' a notification, the reply to which was "yes".
If we were in Tim's shoes, we would have requested to visually see that notification from the bank in question, something that never happened at all; and that would have ended it all for the "american_puppet".
What ensued was nothing short of comical. Readers can see for themselves in the chat history. Tim took a screenshot of his PayPal account, in which no payments had been made. He also went on to point out the blatantly rubbish emails that were in his junk box.
Speaking of emails, those fake receipts were so poorly fabricated that we reckon a first grader could have done better. We have included two of those emails towards the end of this article.
The most ludicrous of all? Those emails were from the address "firstname.lastname@example.com". Obviously it was meant to be read as "service" instead of "serivice"; and the fraudster actually believed it stood a chance of fooling others.
Tim also forwarded us screenshots of another email from the same address which was apparently intended for a separate victim by the first name of "Eddie", whom we assume was ready to ship this fraudster a laptop and a pair of jeans in return for a faux 'payment' of some US$1,650.
We hope that never happened! Eddie, if you were indeed preyed on and are reading this, do not hesitate to contact us.
Tim told us that in the 15 minutes he realized that the entire episode was a staged attempt at defrauding him, he had forwarded those phishing emails to PayPal, reported the account to the relevant administrators of Carousell and wrote in to the Malaysian Police and furnished them with the address the fraudster provided in those emails.
After which, Tim simply told the "american_puppet" that 'her' strings has been pulled by 'her' own stupidity, and wished him the best of luck in suave fashion.
Tim told us that he was almost certain that the fraudster was a male masquerading as a female, which helped to "add a motherly touch" to the entire play - a smart device that worked well until it did not.
Tim notes that the attempt by the buyer was an "ambitious" one and he has never seen anything quite like it. Ultimately, he notes that its failure was the product of "poor execution, too many unnatural signs and over complication". We have to concur.
Sadly, this fraudster will probably never be apprehended and will continue his pillage on other less suspecting victims on such online marketplaces where sellers are overly eager to close a deal, even at the mercy of uncertainty. We urge our readers to remain vigilant and err on the side of conservatism.
Tim tells is that "I'm thankful that I didn't ship the watch out to that idiot," and that he was "happy" overall although he "did miss some market moves on Friday" while he was reeling from the realization of what happened.
For those that wish to pay the fraudster a visit, here is a potential address you might want to visit: "Block A 01-14/15, Cyberjaya, Selangor, Malaysia 63000". May the vigilantes of justice prevail!
If you are part of any news or media outlet and would wish to speak to Tim directly, please contact us.


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By Dyanna Ballou: Dyanna is a first-chair trial attorney who has practiced law for over thirty years, primarily representing defendants in the areas of product liability, toxic torts, medical malpractice, personal injury, and premises liability. She has tried numerous cases to verdict in courts across the country.
The ravages of the nation's opioid crisis are regular topics in the news today. The costs in damaged lives, health-care expenses, lost productivity, and criminal activity are ever-growing. Now a new avenue for recouping those costs is opening: the plaintiffs' bar is actively recruiting state and local governments to sue opioid manufacturers to recover the costs of combating the use of opioids. States, cities, and counties are signing up in record numbers, seeking reimbursement for the costs of battling opioid addiction.
The first lawsuit was filed in 2015 by Mississippi's Attorney General. Now these lawsuits are filed almost weekly. And that certainly will continue, considering the enormous problem of opioid dependency. In 2016, almost 63 million Americans received a prescription for an opioid drug. According to the Centers for Disease Control and Prevention, almost 50 Americans die from an opioid overdose every day. We all are familiar with famous names such as Prince, Heath Ledger, and Tom Petty. They represent thousands of other citizens who have had the same sad fate. In addition to death, drug abuse can result in criminal activity and broken lives as addicts who cannot get the painkillers through legal prescriptions turn to illegal drugs such as heroin and the synthetic opioids fentanyl and carfentanil. Synthetic opioids are a frightening development. Fentanyl is 10,000 times stronger than morphine, and carfentanil is 100 times stronger than an equal dose of fentanyl. Misusing these powerful drugs even once can result in death.
Managing this tidal wave has devastated city, county, and state budgets because of the high costs of police, courts, incarceration, medical care, and addiction treatment. As one example, every day over 1,000 people are treated in emergency rooms for misusing prescription opioids—not to mention the hidden costs of child welfare needs for families torn apart by opioid abuse, babies born to addicted mothers, and even seemingly minor costs such as using city employees to clean up used syringes left in parks. In November 2017, the President's Council of Economic Advisors calculated the cost of the opioid crisis at $504 billion in 2015 alone. Despite this, when President Donald Trump declared the opioid epidemic a public health emergency in October 2017, neither he nor Congress allocated any extra money to state or local authorities to combat the issue.

subset: commoncrawl


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We asked retailers across the country to share their best-selling necklaces this week.
Frasca Jewelers, Palm Desert, Calif. Cherie Chantecler white gold necklace with 163 grams of freshwater pearls, 2.86 cts. t.w. diamonds and tridacna, $19,000. "It's amazing! It's a bigger-than-life kind of piece," says store owner Maria Frasca. "It's fun and chic."
La Mine d'Or, Moncton, New Brunswick, Canada. Custom multicolored sapphire necklace mounted on 18k white gold, $1,800. "It's different—people come here looking for something that is somewhat unique that they don't see in every chain store," says owner and president Andre Cormier.
Lucky Jewelers, St Thomas, U.S. Virgin Islands. Private label diamonds by the yard, $1,500–$3,500. "They're different and very causal," says store president Pash Daswani. "Most people don't want something too fancy-shmancy."
Ford, Gittings & Kane, Rome, Ga. Simon G. platinum, emerald and diamond necklace, price on request. "It's probably the most beautiful necklace we've sold this year!" raves store co-owner Jan Fergerson.
Stucki Jewelers, Grass Valley, Calif. Custom 14k yellow gold necklace with 0.16 ct. t.w. diamonds and 6.7 cts. t.w. opals, $2,650. "Opals have been selling really well," says store co-owner James Arbaugh.
(All photos courtesy of retailers)Follow JCK on Instagram: @jckmagazine
Follow JCK on Twitter: @jckmagazine
Follow JCK on Facebook: @jckmagazine


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It has been long reported by Casino Watch Focus that Internet gambling was made illegal by the Unlawful Internet Gambling Enforcement Act and that countless groups have tried and failed to overturn its ban. The Kansas City Star has outlined the details of the latest attempt to overturn the ban on Internet gambling:
A U.S. appeals court upheld an Internet gambling ban Tuesday, rejecting a challenge from an association of off-shore bookies that the federal prohibition was too vague and violated privacy rights.
The 3rd U.S. Circuit Court of Appeals in Philadelphia rejected arguments from Interactive Media Entertainment & Gaming Association in New Jersey, which had filed the lawsuit hoping to legalize online betting in that state.
Congress passed the Unlawful Internet Gambling Enforcement Act in 2006 to ban online gambling that would be illegal in the state where the individual or gambling business conducts the transaction.
An appeal is still possible, but this is just one more clear victory on the side of keeping gambling on the internet illegal and keeping children and families safe from online predators a priority.
For more information on the dangers of gambling, please visit CASINO WATCH, & CASINO WATCH FOUNDATION


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TV/radio: 7:30 p.m., ABC-7, WMVP-AM 1000.
Storylines: The start of the Tyronn Lue era after Friday's stunning news that the Cavaliers fired coach David Blatt. The Bulls won the first meeting between the teams on opening night in Chicago.
Trending: The Bulls are 2-4 in the second of back-to-back games and their scoring average has dropped 14 points from the first to second game. Kevin Love has posted double-doubles in six of his last seven games.


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Fluida round necklace, silver
Fluida round necklace, silver
Fluida round necklace
Material: Sterling silver, rhinestone
Size: one size (ø 40 cm)
N.B. As every necklace is made as a unique item, each one has its own shapes and might differ slightly from the picture on our e-shop, although the main features of each design will be maintained (i.e. metal, plating, stone). If the item selected is out of stock, it will be made to order and it might take 2 weeks for it to be ready for shipping.
Add To Cart
Price in GBP: 270£
If you would like to pay by GBP please get in touch at firstname.lastname@example.com


text: Dadun Collection: http://hdl.handle.net/10171/52121 2019-08-26T06:48:30Z 2019-08-26T06:48:30Z IL12-mediated liver inflammation reduces the formation of AAV transcriptionally active forms but has no effect over preexisting AAV transgene expression http://hdl.handle.net/10171/36156 2018-03-22T16:17:25Z 2013-01-01T00:00:00Z Title: IL12-mediated liver inflammation reduces the formation of AAV transcriptionally active forms but has no effect over preexisting AAV transgene expression Abstract: Recombinant adenoassociated viral vectors (rAAV) have proven to be excellent candidates for gene therapy clinical applications. Recent results showed that cellular immunity to AAV represents a major challenge facing the clinical use of systemic administration of these vectors. Interestingly, no preclinical animal model has previously fully reproduced the clinical findings. The aim of the present work was to enhance the T cell immune response against AAV capsid in mice by the administration of a rAAV expressing the immunostimulatory cytokine IL-12. Our results indicate that although IL-12 expression enhanced the AAV capsid-specific immune response it failed to eliminate transduced hepatocytes and long-term expression was achieved. We found that AAV-mediated transgene expression is altered by IL-12-induced liver inflammation. However, IL-12 expression has no effect over preexisting AAV-mediated transgene expression. IL-12 down-regulates AAV mediated transgene expression via induction of IFN-γ production by NK and T cells, but without altering the transduction efficiency measured by viral genomes. Our results indicate that liver inflammation affects the formation of transcriptionally active AAV vector genomes through an unknown mechanism that can be avoided by the use of DNA-demethylating or anti-inflammatory agents. 2013-01-01T00:00:00Z Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer http://hdl.handle.net/10171/36151 2018-03-26T10:07:52Z 2011-01-01T00:00:00Z Title: Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer Abstract: Recombinant adeno-associated virus (rAAV) are effective gene delivery vehicles that can mediate long-lasting transgene expression. However, tight regulation and tissue-specific transgene expression is required for certain therapeutic applications. For regulatable expression from the liver we designed a hepatospecific bidirectional and autoregulatory tetracycline (Tet)-On system (Tet(bidir)Alb) flanked by AAV inverted terminal repeats (ITRs). We characterized the inducible hepatospecific system in comparison with an inducible ubiquitous expression system (Tet(bidir)CMV) using luciferase (luc). Although the ubiquitous system led to luc expression throughout the mouse, luc expression derived from the hepatospecific system was restricted to the liver. Interestingly, the induction rate of the Tet(bidir)Alb was significantly higher than that of Tet(bidir)CMV, whereas leakage of Tet(bidir)Alb was significantly lower. To evaluate the therapeutic potential of this vector, an AAV-Tet(bidir)-Alb-expressing interleukin-12 (IL-12) was tested in a murine model for hepatic colorectal metastasis. The vector induced dose-dependent levels of IL-12 and interferon-γ (IFN-γ), showing no significant toxicity. AAV-Tet(bidir)-Alb-IL-12 was highly efficient in preventing establishment of metastasis in the liver and induced an efficient T-cell memory response to tumor cells. Thus, we have demonstrated persistent, and inducible in vivo expression of a gene from a liver-specific Tet-On inducible construct delivered via an AAV vector and proved to be an efficient tool for treating liver cancer. 2011-01-01T00:00:00Z Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse http://hdl.handle.net/10171/35816 2017-05-13T23:33:23Z 2012-01-01T00:00:00Z Title: Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse Abstract: Chronic kidney disease is a long-term complication in acute intermittent porphyria (AIP). The pathophysiological significance of hepatic overproduction of the porphyrin precursors aminolevulinate acid (ALA) and porphobilinogen (PBG) in chronic kidney disease is unclear. We have investigated the effect of repetitive acute attacks on renal function and the effect of total or five-sixth nephrectomy causing renal insufficiency on hepatic heme synthesis in the porphobilinogen deaminase (PBGD)-deficient (AIP) mouse. Phenobarbital challenge in the AIP-mice increased urinary porphyrin precursor excretion. Successive attacks throughout 14 weeks led to minor renal lesions with no impact on renal function. In the liver of wild type and AIP mice, 5/6 nephrectomy enhanced transcription of the first and rate-limiting ALA synthase. As a consequence, urinary PBG excretion increased in AIP mice. The PBG/ALA ratio increased from 1 in sham operated AIP animals to over 5 (males) and over 13 (females) in the 5/6 nephrectomized mice. Total nephrectomy caused a rapid decrease in PBGD activity without changes in enzyme protein level in the AIP mice but not in the wild type animals. In conclusion, high concentration of porphyrin precursors had little impact on renal function. However, progressive renal insufficiency aggravates porphyria attacks and increases the PBG/ALA ratio, which should be considered a warning sign for potentially life-threatening impairment in AIP patients with signs of renal failure. 2012-01-01T00:00:00Z Immunology and gene therapy: shoulder to shoulder into the fray http://hdl.handle.net/10171/21805 2017-05-14T19:59:44Z 2010-01-01T00:00:00Z Title: Immunology and gene therapy: shoulder to shoulder into the fray 2010-01-01T00:00:00Z Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells http://hdl.handle.net/10171/21804 2017-05-15T02:22:17Z 2005-01-01T00:00:00Z Title: Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells Abstract: Cancer immunotherapy has been extensively attempted by gene transfer of cytokines with viral vectors. In this work, we compared the therapeutic effects of interleukin 12 and 15 (IL-12 and IL-15) genes transferred to tumor cells or to dendritic cells (DCs), which were subsequently injected into established tumors. For this purpose, we used viral vectors based on simian virus 40 (rSV40). Importantly, we observed that nonmatured DCs infected with rSV40 vectors remained phenotypically immature. Infection of CT-26 tumor cells with rSV40 expressing IL-12 (rSVIL-12) or IL-15 (rSVIL-15) failed to inhibit tumor development. In contrast, the intratumoral administration of syngeneic DCs transduced with rSVIL-12 or rSVIL-15 was associated with a strong antitumor response; up to 40% tumor remissions were achieved with DCs transduced by rSVIL-12 and 73% with DCs expressing IL-15. This antitumor effect correlated with the in vivo priming of tumor-specific CD8+ T lymphocytes. Depletion studies showed that rSVIL-15-mediated antitumor efficacy was mediated mainly by CD8+ T lymphocytes and NK cells. We conclude that (i) SV40-derived vectors are an advantageous alternative to transduce genes into DCs and (ii) DCs transferred with IL-15 have an enhanced capability to induce curative antitumor immunity when injected into malignant lesions. 2005-01-01T00:00:00Z Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria http://hdl.handle.net/10171/21803 2017-05-14T14:50:13Z 2010-01-01T00:00:00Z Title: Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria Abstract: BACKGROUND & AIMS: Acute intermittent porphyria (AIP) is characterized by hepatic porphobilinogen deaminase (PBGD) deficiency resulting in a marked overproduction of presumably toxic porphyrin precursors. Our study aimed to assess the protective effects of bone marrow transplantation or PBGD gene transfer into the liver against phenotypic manifestations of acute porphyria attack induced in an AIP murine model. METHODS: Lethally irradiated AIP mice were intravenously injected with 5x10(6) nucleated bone marrow cells from wild type or AIP donor mice. To achieve liver gene transfer, AIP mice received via hydrodynamic injection plasmids expressing human PBGD or luciferase, driven by a liver-specific promoter. RESULTS: Erythrocyte PBGD activity increased 2.4-fold in AIP mice receiving bone marrow cells from normal animals. Nevertheless, phenobarbital administration in these mice reproduced key features of acute attacks, such as massively increased urinary porphyrin precursor excretion and decreased motor coordination. Hepatic PBGD activity increased 2.2-fold after hydrodynamic injection of therapeutic plasmid. Mice injected with the luciferase control plasmid showed a high excretion of porphyrin precursors after phenobarbital administration whereas just a small increase was observed in AIP mice injected with the PBGD plasmid. Furthermore, motor disturbance was almost completely abolished in AIP mice treated with the therapeutic plasmid. CONCLUSIONS: PBGD deficiency in erythroid tissue is not associated with phenotypic manifestations of acute porphyria. In contrast, PBGD over-expression in hepatocytes, albeit in a low proportion, reduced precursor accumulation, which is the hallmark of acute porphyric attacks. Liver-directed gene therapy might offer an alternative to liver transplantation applicable in patients with severe and recurrent manifestations. 2010-01-01T00:00:00Z Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex http://hdl.handle.net/10171/20432 2017-05-13T06:29:33Z 2005-01-01T00:00:00Z Title: Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex Abstract: The induction of IFN-gamma-secreting CD8+ T cells and neutralizing antibodies to HIV-1 are both key requirements for prevention of viral transmission and clearance of pathogenic HIV. Although DNA vaccination has been shown to induce both humoral and cellular immune responses against HIV antigens, the magnitude of the immune responses has always been disappointing. In this report, we analyze the ability of polyethylenimine (PEI)-DNA complex expressing an HIV-glycoprotein 120 (gp120) antigen (PEI-pgp120) to induce systemic CD8+ T cell and humoral responses to the gp120 antigen. The administration of PEI-plasmid complex resulted in rapid elevation of serum levels of IL-12 and IFN-gamma. Furthermore, a single administration of PEI-pgp120 complex elicits a number of gp120-specific CD8+ T cells 20 times higher than that elicited by three intramuscular injections of naked DNA. Interestingly, we found that systemic vaccination with PEI-pgp120 induced protective immune responses against both systemic and mucosal challenges with a recombinant vaccinia virus expressing a gp120 antigen. The data also demonstrated that the depletion of macrophages with liposome-encapsulated clodronate completely abolished gp120-specific cellular response. Overall, our results showed that a single administration of PEI-pgp120 complexes, eliciting strong immune responses, is an effective vaccination approach to generate protection against systemic and mucosal viral infections. 2005-01-01T00:00:00Z The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma http://hdl.handle.net/10171/20371 2017-05-13T01:56:41Z 2007-01-01T00:00:00Z Title: The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma Abstract: Better understanding of the mechanisms that mediate spontaneous immune rejections ought to be important in the quest for improvements in immunotherapy of cancer. A set of intraperitoneal tumors of mesenchymal origin that had been chemically induced in ubiquitously expressing EGFP transgenic mice provided a model in which both T and NK cells were absolutely required for tumor rejection. Tumor cells were traceable because of being fluorescent and readily grafted in RAG1(-/-) immunodeficient mice, whereas they were rejected in a majority of syngeneic C57BL/6 and EGFP-transgenic mice. Tumor-cell clones with the highest EGFP expression tended to be rejected, but a direct involvement of EGFP as the antigen recognized for the immune rejections was ruled out. Rejections were absolutely dependent on NK cells as well as on CD4(+) and CD8(+) T lymphocytes according to selective depletion studies. Furthermore, CD8(+) and CD4(+) T lymphocytes as well as NK cells were detected in the inflammatory infiltrate that mediates tumor rejection along with some DC. The effects of IFN gamma, produced at the tumor site by T and NK lymphocytes, were only required at the malignant cell level and were necessary for tumor eradication. NK recognition of tumor cells was mediated by the NKG2D-activating receptor and blocking its function in vivo partially interfered with rejection. Therefore, complete rejection of these mesenchymal tumors requires a concerted set of activities including direct tumor-cell destruction and IFN gamma production that are mediated by both NK and T cells. 2007-01-01T00:00:00Z


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Lately I've had something strange happen and I'm wondering if there's a way around it.
I join a battle and it starts loading. For whatever reason I get "waiting on players" for a very long time. I think it's always when there's just one human opponent. The game times out and loads the hanger but my plane remains "in battle" until the next day. I've tried disconnecting from the server and getting out and back into the game with no luck. Any suggestions? I'd really like to fly my IL-2(t) to kill some AA for a mission but it's flying in some alternate dimension at the moment.


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Tag: health research regulation
Governing Health Research from Within: Empowering the Actors Who Occupy Regulatory Spaces – 26‐27 January 2017: Wellcome, London
In January, Liminal Spaces colleagues held a workshop 'Governing Health Research from Within: Empowering the Actors Who Occupy Regulatory Spaces'.
Workshop description:
The architecture of health research has vastly expanded over the past two decades. Today,research involves and crosses between genomic data, tissue, health and lifestyle data, metadata and social media, reaching far into the private spheres and interests of patients, research participants and the wider population. This creates many new regulatory objects requiring attention, and also blurs distinctions between traditional roles such as clinician/researcher, and patient/participant. These developments often result in a burgeoning of silo‐based regulatory spaces – focusing respectively
data/tissue/cells/trials/databases/internet – which are being occupied with an ever‐expanding population of new actors, far beyond the classic actors such as regulators and self‐selecting patient groups. This workshop sought to identify the dynamics affecting this expanding range of actors and the challenges that they face in navigating and influencing health research through regulation. It also sought to examine deep questions about how these actors can be empowered, together with traditional regulators, to co‐produce optimal governance and practices across the entire spectrum of human health research. In short, we aimed to begin reimagining health research regulation in terms of the human practices experiences that drive it, while developing methods to evaluate those
influences and their role in determining what counts as good governance.
The workshop report can be found here.
AllegraLab Article: Liminality, Biomedicine, and the Law – A Symposium Supported by the Wellcome Trust
The Liminal Spaces team discuss their recent symposium on liminality and health research regulation in the United Kingdom with AllegraLab.
Liminality, Biomedicine, and the Law – A Symposium Supported by the Wellcome Trust
Biomedicine and the life sciences continue to rearrange the relationship between culture and biology, problematizing what it means to be a person, and introducing uncertainty and instability to individual and public life. When this occurs, law is often called upon in response. Is this the best option? Why do we always turn to law to deal with ethical tensions or uncertainty in technoscience?
Liminal Spaces Team Holds Symposium on Health Research Regulation and Liminality
In May 2015, the Liminal Spaces Project team held a one-day workshop to discuss health research regulation in the United Kingdom.
Biomedicine and the life sciences continue to rearrange the relationship between culture and biology, problematising what it means to be a person, and introducing uncertainty and instability to individual and public life. When this occurs in regulation, law is often called upon in response. Is this the best option? Could an anthropological concept developed to make sense of ritual, structure and agency help us to better understand the profound sociotechnical challenges that continue to redefine life in the age of biobanks, gene and stem cell therapy, and other novel medico-scientific domains? Liminality refers to a threshold state characterised by possibility, marginality and transformation. Early research into liminal states helped to better understand the relationship between structure and agency, drawing attention to the connection between transformation and a given society's underlying organisation and values. As temporal and spatial spaces of change, liminal states are also the sites of and for reflection.
Dangerous Spaces
Dangerous Spaces engage regulatory hindrances that contribute to the notorious Valley of Death in commercial innovations.
» Read more
Clogged Spaces
Liminal Spaces
The key goal of this research is to provide the first-ever integrated, interdisciplinary and cross- cutting analysis of health research regulation (HRR). The research confronts the gaps between documented law and research practice – i.e liminal regulatory spaces – and promotes an holistic approach thus far absent in HRR.
The liminal spaces framework suggests opportunity to move within and between spaces, but also exposes uncertainty and instability. When this occurs in regulation, law is often called upon. Crucially, this research challenges that response.
Four research strands will engage stakeholders to ask: what is happening in the liminal spaces of HRR; what lessons can be learned across sectors and jurisdictions; and how can we better exploit liminal regulatory spaces?
The four strands are:


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Thats a ship i coded for, look for _mk2 in the _bonus files... i think...
Its been a decade since i worked on it so i could be wrong
This member has provided no bio about themself...
Thats a ship i coded for, look for _mk2 in the _bonus files... i think...
Its been a decade since i worked on it so i could be wrong
AS someone whos gone over the actual screen used models, I can confirm that they are not hangars, they are meant to be storage bays. But they do also have the same texture, and door layer as the main hangars, so you can take from what what ever you want hahaha
Theres more details in my gallery images.
wth are you talking about?
The two bottom images are the set design overlaying the bridge location, to scale
Sorry CKYRules, Im not allowed to share it. Im officially archiving as many as I can get on behalf of the old production team. And in the process im doing up specs like this for the fans.
Does it say a specific line thats causing it? Because the more detials the easier it is to fix
looks like your using something similar to the stargate peg chron guys
does what? ctd?
sorry for the late reply, i dont drop y here often
Program for 3d models is 3dsmax with the .alo plugin
Xml editing is notepad
Lua was done by someone else, in a program i dont know
Anyway hope that helps
While im not part of the team, i did do some digging into this a long time ago, its not something thats easy to do, so i put it in the far to hard column.
Instead this engine just uses the age old unit upgrade system
Heads up guys, humble bundle has the steam EAW gold pack again, might be worth spreading the word :D
Trust me, stargate is my first love, not trek or wars, one of the other battle pages is Apollo vs Ent-E lol
Really? I posted a blog about my new project up the other day O.o
Just checked and it was set to delay post, its live now
Check ya facebook page for people who have tagged you, was talking to Rainbow Sun Franks about it earlier, he took a look, and he had one word to describe it... and ill leave that for you to find :D
I jsut dont have the time, and im converting it into a TV show... check out deadliest fandom on facebook
Check out the details here
Go here to check out the details :D
I have BSG stuff in scifi at war, as long as u link to it, u can use it
if you want to see the concept art
Download the installer - Moddb.com
And it should auto detect the steam version in the options. This will give you the FOC version
For the older EAW version, you should look at this to install it - Forums.steampowered.com
Open invite to the creators of this mod to come on my podcast in a few weeks. Its recorded at 7pm monday night GMT +10 (Brisbane Time)
If you want to join us message me either here, or on Skype at savescifipodcast
We do it live every week at the same time. If you want to join us and have a chat your welcome to
Heres some of our other podcasts
this is a patch for the graphics xml file that should fix it on some systems but may not fix it on others, thats what ive been told
this is the graphics fix isnt it?
its mainly used because its our point of origin and something they can copyright to make the name/brand unique
EAW Gold pack but only for a few days...
The Dialing this is something I added, ages ago, and since im not in the mod anymore, they are doing something different
one of the reasons they didnt use it in the show
I knew from the start, i promised not to tell :D
I know what it is, but I promised I wouldn't say, so instead I will only drop a hint
"fragile balance"
Thats the best I can do, if you are curious beyond that, well you will just have to wait :D


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Get an overview of this hotel Luxury London hotel in London City Centre, walk to Tate Modern
VIP Access™ Hotel
Our customers receive consistently exceptional service at these hotels.
Expedia Rewards members get double value for their points when booking any VIP Access hotel.See details
Popular highlights
Located in London City Centre, this luxury hotel is within a 15-minute walk of Tate Modern and Coca-Cola London Eye. The Shard and Big Ben are also within 1 mi (2 km). Southwark Underground Station is 8 minutes by foot and Blackfriars Underground Station is 8 minutes.
Hotel features
A restaurant, 2 bars/lounges and a 24-hour fitness centre are available at this smoke-free hotel. WiFi in public areas is free. Additionally, valet parking, 24-hour room service and a meeting room are on-site.
Room amenities
All 359 individually decorated rooms feature free WiFi and 24-hour room service. For a bit of entertainment, LED TVs come with satellite channels, and guests will also appreciate thoughtful touches such as bathrobes and slippers.Information missing or incorrect? Tell us!Opens in a new window
Sea Containers London
Hotel Amenities
Hotel Amenities
The hotel offers a restaurant. Guests can unwind with a drink at one of the hotel's 2 bars/lounges. Wireless Internet access is complimentary. This luxury hotel also offers a 24-hour fitness centre, multilingual staff and concierge services. Limited on-site parking is available on a first-come, first-served basis (surcharge).
Sea Containers London is a smoke-free property.
- Luggage storage
- Lift
- ATM/banking
- Number of bars/lounges - 2
- Breakfast available (surcharge)
- Concierge services
- 24-hour front desk
- Banquet hall
- Parking (limited spaces)
- Porter
- Express check-out
- Restaurant
- Total number of rooms - 359
- 24-hour fitness facilities
- One meeting room
- Number of floors - 14
- Dry cleaning/laundry service
- Free WiFi
- Valet parking (surcharge)
- Smoke-free property
- Multilingual staff
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Valet parking (surcharge), Parking (limited spaces)
Room Amenities
- Towels provided
- Linens provided
- Hypo-allergenic bedding available
- In-room climate control (air conditioning)
- Phone
- Free bottled water
- Daily housekeeping
- Turndown service
- Private bathroom
- Bathrobes
- Free toiletries
- Hair dryer
- Slippers
- Desk
- Iron/ironing board
- In-room safe
- Blackout drapes/curtains
- Satellite TV service
- Free WiFi
- Room service (24 hours)
- Individually furnished
- Individually decorated
- Connecting/adjoining rooms available
Where to Eat
Buffet breakfasts are available for a surcharge on weekdays between 6:30 AM and 11:00 AM and at the weekend between 7:00 AM and 11:30 AM.
Sea Containers – This restaurant specialises in British cuisine and serves breakfast, brunch, lunch and dinner. Guests can enjoy al fresco dining (weather permitting).
12th Knot – On-site rooftop bar. Open selected days.
Lyaness – On-site cocktail bar. Open daily.
24-hour room service is available.
Start your day with a buffet breakfast, available for a surcharge on weekdays from 6:30 AM to 11:00 AM and on weekends from 7:00 AM to 11:30 AM. You can order up room service around the clock.
Nearby Things to Do
Recreational amenities at the hotel include a 24-hour fitness centre.
The recreational activities listed below are available either on-site or nearby; fees may apply.
- Fitness classes on site
- Yoga classes/instruction on site
Spa Services
- Prenatal massage
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- Accessible bathroom
- Roll-in shower
Hotel Policies
Check-in time starts at 3:00 PM
Check-in time ends at 5:30 AM
Minimum check-in age is 18
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Kids stay free! One child stays free when using existing bedding.
- Rollaway/extra beds are available for GBP 50.
- Cribs (infant beds) are not available.
- Pets stay for free
- 1 per room (up to 20 lb)
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card, debit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
Only service animals are allowed
No cots (infant beds) available
Pets allowed (no fees)
- Deposit: GBP 100 per night
Optional extras
- Fee for buffet breakfast: GBP 22.50 per person (approximately)
- Valet parking fee: GBP 45 per day
- Pet deposit: GBP 100.00 per stay
- Late check-out is available for a fee (subject to availability, amount varies)
Hotel Name
- Mondrian London Hotel
- Mondrian Hotel
- Mondrian London
- Mondrian
- Mondrian London At Sea Containers England
- Sea Containers London
- Sea Containers London Hotel
- Sea Containers London London
- Sea Containers London Hotel London
We should mention
Reservations are required for massage services and spa treatments. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation. Only registered guests are allowed in the guest rooms. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


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OWL named as Innovation Award Finalist
In March 2016, Organic Waste Logistics (OWL) had the privilege of being named a finalist at the 2016 World Food Innovation Awards in the category, Best Environmental Sustainability/CSR Initiative. The award, which was presented during the Hotelympia Conference in London on 5-8 March, was judged by a panel of experts, who considered 240 entries from 25 countries in 25 categories.
Both OWL Co-Founders, William Heller and Mat Stewart attended the ceremony to receive the honour and were extremely pleased to be selected as one of three finalists in this category.
"As OWL had just launched at the Hotelympia show, we were thrilled to be notified that we had been named as finalists for the best environmental sustainability award" said William Heller, OWLs Chief Executive. "This was a surprise and honour for such a new and young company."
"Since we received this accolade, we have been working across the UK and overseas to spread the word about OWL which provides a state-of-the-art solution for the management of unavoidable food waste."
"We're pleased that interest in OWL has increased substantially and that we're now beginning to install our BioWhale in sites across the UK."
The World Food Innovation Awards is the international food industry's leading awards scheme, celebrating innovation and excellence across every product category, as well as seeking out the best in packaging, marketing, technology and sustainability.
Written by
Beth Heller


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My beautiful and talented fiancee Carrie came up with this while sampling the Prime Rib Rub. It's actually better than my mom's and easy as pie to make (though good pie is actually quite difficult.)
Try it, you'll love it.
spread English Prime Rib Rub Liberally on the roast.
sear on both sides, place in slow cooker/crock pot.
Make onion soup mix according to package instructions, use to deglaze pan that you seared roast in. pour all liquid and little bits in crock pot with roast.
Add carrots, celery, potatoes and onions
Slow cook for 6+ hours.
Meat will fall apart on its own, saves you from having to set out knives or cleaning them.
The more onions the better, in my opinion.
Do you have a recipe you'd like to share with The Spice House community? We are currently gathering recipes to include in our collection and we would love to share yours online.Submit Yours


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Cupping Methods
Cupping Massage- Massage Cupping is a modern adaptation of the ancient art of cupping therapy. While massage performed by applying pressure, cupping instead uses negative pressure to pull, lift, open and expand the body's soft tissues.
Biomagnetic Cupping- Biomagnetic Therapy is a modern adaptation of the ancient art of cupping therapy. Biomagnetic Therapy assists the body to regain it's own self-healing electromagnetic balance naturally. Lack of magnetism may cause stress mental disorders, headaches, arthritis, muscle pain, osteoporosis, chronic fatigue, allergies, insomnia, inflammation, bowel disorders, and many other degenerative problems.
Facial Rejuvenation Cupping- Facial cupping is an all-natural alternative to a surgical facelift or chemical treatments. It will tone your facial muscles, fill and tighten your skin, and reduce the amount of puffiness you may have under your eyes. Cupping can literally give you a face lift by improving the blood circulation to your facial muscles. You will soften and even lose wrinkles.
Facial cupping is also very effective in draining sinuses,and dredging infection and inflammation.
Abdominal Cupping-Abdominal massage cupping externally manipulates the digestive and reproductive systems. It works small and large intestines, stomach, colon, and reproductive organs. Many illnesses come from a toxic colon.Cupping is an excellent therapy for the belly. It stretches the walls of the organs, thus sloughing off stagnant waste and mucus and overall promote the activity of digestion.People consistently report expelling an excess amount of waste immedietely follwing treatments and an increase of eliminations througout the day.Cupping is regularly, and with great success, being used to help in conception, handle IBS, constipation, diarhea, distention and acidity.
Fire Cupping-
An Eastern acupuncture therapy called fire cupping may sound like medieval alchemy, but it is actually quick…painless…and extraordinarily effective for a range of health conditions, including severe muscle stiffness and arthritis.
What Is Fire Cupping?
Cupping is a traditional Chinese therapy used to treat illnesses and imbalances for over 2,500 years. Originally, the "cups" were made from animal horns, and practitioners used their own lips to create suction.
According to Michael Gaeta, president of the Acupuncture Society of New York, there are two predominant forms of modern cupping therapy. In both, a practitioner creates suction in a cup, applies the cup to the patient's body, and in response to the suction, blood rushes to the area and the skin at the contact site is "sucked up" into the cup.
Newer methods of cupping use mechanical devices to create the suction. The more traditional method, however, creates suction by applying heat to the cup—such as from a lighted candle—hence the name "fire cupping".
Usually, a number of suctioning cups are applied to the patient's skin for several minutes and then removed. While cupping is not considered painful, it may leave round red marks on the skin for a day or more. One way to think of cupping is to compare it to a massage, but in reverse: the cups pull your muscles up, rather than pushing them down.
Ultimately, fire cupping brings the same relief from body aches and pains that a deep massage would offer. However, cupping takes less than half the time—just 5 to 15 minutes!
Cellulite Cupping Treatment- Cellulite is a term for the dermal, lumpy and dimpling appearance caused by the deposits of underlying adipose tissue and stuck connective fascia.It occurs due to poor blood circulation, capillary and lymphatic clogs, and buildup of toxins in the body.As a result, body tissue becomes weak and under nourished, and toxins trap themselves in and around fat cells, particularly in the subcutaneous layer.Cellulite can affect any person, of any size or weight, generally showing up in the abdominal, thigh, hip, and buttocks area. Almost all women show some degree of cellulite on their bodies.Though there are many theories out there in regards to the reduction or elimination of cellulite, we know that diet, exercise and water aren't enough. The cupping works very effectively for removing swelling, local fat elimination, accelerating healing of scar tissue and stretch marks and restoring skin compactness in problem areas of the body.
Cupping increases blood circulation and stimulates lymph flow. It removes the swelling and eliminates toxins, clearing away any stagnation.It also breaks up the fatty tissues or cellulite deposit, which in turn make the skin firm and smooth. During cupping , the skin develops collagen and elastin, which improves skin texture and tone.


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The website is under going a bit of renovation at the moment. The new site will be set up in sort of 3 different areas... -one section focusing on weddings with pricing & fantastic pictures
-the main site with my galleries and contact info
-and of course the blog here with my usual news, announcements, blabbering and fun pictures
So stay tuned as I tweak the site a bit and you will soon see a revamped weddings section as well! For now, a little picture fun from my favorite coffee shop in Chicago. The Noble Tree located in Lincoln Park. Cheers!


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The 17th Century Farmhouse That Became a Greek Hotel
Eat. Stay. Love. | Presented by Edward Jones Metohi Kindelis, a hotel on the Greek Isle of Crete, also serves as an organic farm and features a building that dates back to before 1650. Guests can relax on the beautiful Greek beaches while enjoying yoga, detoxes and the original indigenous food of Crete.


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Diggin' Downtown Napanee - Phase 3
Diggin' Downtown Napanee - PHASE 3
Diggin' Downtown Napanee - PHASE 3
Please be advised that due to unforeseen circumstances the Forest Mills Bridge closure scheduled to start today had been delayed. This bridge remains open and will not be closed until Monday June 3, 2019.
Please be advised that National Structures has been contracted by the County of Lennox & Addington to rehabilitate the Forest Mills Bridge on County Rd 12 in Greater Napanee.
Please be advised that Coco Paving has been contracted by the County of Lennox & Addington to rehabilitate County Rd 2 in Loyalist Township, from Morven Creek Bridge (just west of Fralick Road), easterly to County Rd 4 (Roundabout). The rehabilitation generally consists of drainage improvements (ditching & culverts), removal of existing asphalt, and re-paving including paved shoulders.
Effective Monday, May 1st, the intersection of Dundas Street and Centre Street and the intersection of Dundas Street and Robert Street will be closed to traffic. This is required to facilitate the set-up and operation of the required pumping equipment so crews can install the new sanitary, storm, and watermains within the block. The underground work is scheduled to be completed mid-June. The surface restoration work will follow immediately afterwards with the intent to re-open the intersections prior to the July 1st (Canada Day) weekend.
The County of Lennox & Addington and the Town of Greater Napanee are pleased to announce that Len Corcoran Excavating (LCE) has been chosen as the contractor for Phase 1 of the Dundas Street Reconstruction Project, otherwise known as "Diggin' Downtown Napanee".


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Published on September 4th, 2017 | by Rima J Pundir
The Truth Behind Mineral Oil
Many cosmetic agents proudly proclaim 'mineral oil' as an ingredient, while organic-beauty fanatics denigrate it as a petroleum derivative. What is the truth behind mineral oil then?
Mineral oil is a petroleum derivative, yes. It's also as natural as any other nature-derived substance. Again, yes – it is derived from crude oil but how does that make it any worse than say bat droppings or bull semen – commonly used as exotic and effective skin care ingredient in today's search for youth's elixir! Let's dispel some myths about mineral oil…
Myth: Mineral oil "suffocates" skin
Truth: Mineral oil does form a barrier between the skin and the environment – but that is what any good moisturizer does. Mineral oil forms a thin layer on your skin, keeping in the hydration and being what a good emollient does – act as an occlusive agent – keeping moisture in where it belongs.
Myth: Mineral oil strips skin of vitamins
Baseless, fact-less and definitely research-less. Propagated by brands that do not have mineral oil as an ingredient – this is just a beauty claim that is unsubstantiated but since the beauty industry is not regulated so much when it comes to claims, it has become a successful negative propaganda.
Myth: Mineral oil causes allergies
If you are proven to be allergic to petroleum-derivatives, yes, you can have an allergy to mineral oil. Else, mineral oil in fact is used in many rash and burn creams to soothe and treat damaged skin.
Myth: Mineral oil prevents collagen absorption
Let's face it, most collagen molecules in creams are too big for them to be absorbed by the skin in first place. Even if they are small enough, they do not bond with the skin's natural collagen. But it has no effect on collagen absorption, in any case.
Myth: Mineral oil is unsafe
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Shayna Maidel, A
At the TimeLine Theatre
By Dan Zeff
Chicago—When Barbara Lebow's drama "A Shayna Maidel" opened in 1985, the Holocaust was still largely a living memory. Now, a third of a century later, the play inevitably has lost some of its historical immediacy, but it remains a superb family drama, enhanced by a spot-on revival at the TimeLine Theatre.
The play is set in Brooklyn in 1946. It basically recounts what happens when the two Weiss sisters reunite after years of separation because of the Holocaust. Rose Weiss and her father Mordecai left Poland in the 1930's when Rose was four years old and settled in New York City. Left behind were older sister Lusia and her mother. The mother died in the Holocaust but Lusia survived and now has been brought to the United States by her father. The play traces the relationship between Rose and Lusia as it advances from initial wariness and uncertainty.
The sisters have lived in different worlds since childhood, Lusia enduring the horrors of the Holocaust while Rose has become Americanized, her Jewish roots submerged by her assimilation into the New World with virtually no memory of her European Jewish childhood. The story unfolds in a series of scenes that shift from postwar Brooklyn to flashback scenes of family life back in Poland. The play recounts how Lusia and Rose gradually close the personal gap that had separated them for most of their lifetimes.
In an understated high-risk scene dramatically, the father and Lusia compare names they have accumulated in notebooks trying to trace the fates of family and friends caught up in the destruction of the Holocaust. The father reads off one name after another from his little book and Lusia responds with the results of her investigations. Nearly the entire list died in concentration camps or simply disappeared, including close members of the Weiss family. The almost matter-of-fact exchange of names between father and daughter only underscores their pain and sense of loss.
The Holocaust casts its dark shadow over the family but there are no grim descriptive scenes in the death camps. Lusia hints at the abominations of the camps but the playwright does not delve into the environment of violence and death that marked the camps. The story may be set against a horrific background, but it triumphs as an intimate and absorbing family drama mostly acted within the walls of Rose's Brooklyn apartment.
Perhaps the most striking image in the play is Lusia's first entrance, framed in Rose's apartment door for the first time as she is about to launch a new life built on the ashes of the old one. Emily Berman steps through the doorway, slender, pale, and severe looking, in striking physical contrast to Bri Sudia's pure Americanized Rose. A first look at Berman's Lusia says everything the audience needs to know about the character's past suffering and present uncertainty. Berman, honest and credible. doesn't act Lusia, she inhabits the woman's heart and soul.
Bri Sudia never disappoints a Chicagoland audience, whether she stars in a musical, Shakespeare, or Jane Austen. Her Rose mostly reacts to Lusia but every change of facial expression or body language helps build her character. In one high risk scene late in the play, Rose breaks down in a burst of emotionalism that with some performers might be a bit over the top. Sudia nails the scene. Those tears glistening in her eyes are genuine (Sudia leaves the production October 21 to be replaced by Emily Glick).
The supporting cast is without flaw. Charles Stransky is superb as the father, a tyrannical Old World patriarch who internally carries his own burdens dating back to the 1930's when he left his wife and Lusia behind in Poland, taking only Rose with him to America. Carin Schapiro Silkaitis exudes warmth and humor as the selfless mother. Sarah Wisterman has some fine cameo appearances as Lusia's delightful high-energy but doomed friend Hanna. Alex Stein is excellent as Duvid, Lusia's young husband who has his own dramatic story to tell.
Whenever there is a production this sensitive and moving, the audience can look to the director for commendation. Vanessa Stalling gets the props for orchestrating a staging that clearly presents a narrative that switches back and forth in time and place. There is no emotional manipulation in Stallings' staging but plenty of truth and honesty. The second act does lurch a bit in reaching repeated emotional climaxes, but that's on the author and not the director.
The production profits from Collette Pollard's highly detailed three-room Brooklyn apartment, comfortable enough to rent out after the show ends its run. Samantha Jones sets the period tone with her 1940's costume styles. Rachel Levy designed the lighting and Jeffrey Levin the sound. Elise Kauzlaric, credited as "dialect designer," guides Berman through her dual broken English and unaccented English, depending on the language Lusia is speaking. And Bri Sudia's Brooklyn accent seemed spot on.
"A Shayna Maidel" has its historical resonances, but above all it is a story of a family coming together to overcome chilling obstacles that would defeat less resilient characters. The play has had a long life in regional theaters as well as a long run off Broadway. Its success is easily understood. It connects with audiences of all ethnic and religious persuasions with its humanity. The play's title is Yiddish for "Beautiful girl," a term used a couple of times as a fitting grace note to a stirring drama.
The show gets a rating of
"A Shayna Maidel" runs through November 4 at the TimeLine Theatre, 615 West Wellington Avenue. Performances are Wednesday through Friday at 7:30 p.m., Saturday at 4 and 8 p.m., and Sunday at 2 p.m. Tickets are $40 to $54. Call 773 281 8463 ext. 6 or visit timelinetheatre.com.
Contact Dan at email@example.com. August 2018
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Checkmate, My Lord
- $6.99
- $6.99
Publisher Description
Praise for A Lady's Revenge:
"Devlyn makes a unique mark on the genre with her powerful prose and gripping theme."—RT Book Reviews, 4 Stars
The Stakes Are High, The Players in Position...
Catherine Ashcroft leads a quiet life caring for her precocious seven-year-old daughter, until a late-night visitor delivers a startling ultimatum. She will match wits with the enigmatic Earl of Somerton, and it's not just her heart that's in danger.
Let the Games Begin...
Spymaster Sebastian Danvers, Earl of Somerton, is famous for his cunning. Few can outwit him and even fewer dare challenge him-until now. After returning to his country estate, his no-nonsense neighbor turns her seductive wiles on him- but why would a respectable widow like Catherine risk scandal for a few passionate nights in his bed?
"Devlyn reveals the darkness of the spy game and entices readers with a talented and determined heroine."—Publishers Weekly
"Wildly romantic, quick paced, and entertaining from beginning to end."—The Book Girl
"Dark and sexy...full of adventure and mystery but also a powerful love story...a must read."—My Book Addition Reviews
The second book in Devlyn s Nexus series (after A Lady s Revenge) craftily combines espionage in Regency England with a healthy dose of sizzling romance. Widow Catherine Ashcroft has asked Sebastian Danvers, Lord Somerton, to examine her husband s last letters to her, believing they hold the clues to Ashcroft s murder. Sebastian, a spy for the Crown, agrees to assist her; he has little else to do, having been banished from London while his ties to a double agent are investigated. As Sebastian resumes his neglected duties as lord of Bellamere Park, Catherine helps him to regain the trust of his tenants. Her willingness to embark on a love affair with him baffles Sebastian, who clearly wants no long-term relationship and wonders whether her persistence masks hidden motives. Catherine s struggles as a widow and the mother of a young daughter reveal a hidden strength not often present in Regency-era heroines, and Sebastian s dark, emotionally guarded demeanor is laced with complexity that only the most stalwart heroine can unravel. Devlyn s seamless writing will entice readers and keep them eager for the next installment.


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I liked your last post. I use the phrase "guilty pleasure" many times but I've never really thought about what it meant. I used to be embarrassed by things like that but since I turned old and have no time for this shit I proudly declare my love for K$sha and Taylor Swift for the world to see. I'll attempt to strike it from my vocabulary.
As a really clumsy segue: do you know who I would love to strike from my vocabulary? Staunch republicans. I feel like whenever something dumb is happening in politics I don't even need to ask what happened; I feel safe with my guess of "the republicans got so rich they're sick of the populous and are proposing a bill to have us all rounded up into camps."
Seriously. The recent law in North Carolina about barring transgender people from using the bathroom they identify their gender with is so frustrating to hear about.
You don't know what I'm talking about? Well the governor of North Carolina (R) signed into effect a bill that prevented local governments from enacting individual discrimination laws. Sounds great! Until that same law also said that people must legally use the bathroom that corresponds with their biological sex.
I.E. A woman born a man must use the men's bathroom.
The law does say that if you have gender reassignment surgery you have your birth certificate changed! Whoo! Thank god gender reassignment surgery isn't complicated, dangerous, or hard to get!
The people in N.C. say this is to prevent sexual predators from entering the bathrooms under the guise of being transgender. Are you fucking kidding me. There have been very few instances where this has ever happened, and even when it does it wasn't a transgender person committing the crime. It was some sicko committing a crime.
Thank god we changed this law. It'll stop those people who have been breaking laws in the first place from breaking laws! Laws stop criminals all the time! Do you think this'll stop any predators? If a person wants to enter the bathroom to commit a heinous crime this isn't going to stop them. In fact: there is already a case of a dude following a woman into a bathroom to confirm her gender! So your fucking law just caused the thing you wanted to prevent! 'MERICA GODDAMNIT.
You know what? To protect our men, women, and children- just to be safe- we should build separate water fountains and schools!
Out of fear and short sighted ignorance, North Carolina took an incredulous step backwards for civil rights. Transgender people have a hard enough time just being alive, and you want them to feel incredibly unsafe entering a bathroom they don't identify with? So a transgender woman who's been taking estrogen and works hard to have a convincingly female body now has to walk into a men's bathroom? I mean, your right, they have nothing to fear: hate crimes are illegal, too. The law will protect them like its protecting all the men and women its protecting.
Why not just post soldiers at the doors? Oh wait. You're right though, we'll deal with that later. After we're done alienating some of our citizens.
Guh. I see these headlines and its always a republican.
Proudly demanding that people have no choices in their own lives.
They are so terrified of their own shriveled micro-dicks that they can't handle anything vaguely related to sexuality or genitalia. Planned Parenthood?! Providing free help and health care to young teens and people who can't afford this shit? NOT ON MY WATCH! THIS IS AMERICA! THE ONLY PERSON WHO CAN MAKE DECISIONS ABOUT YOUR GENITALS ARE OLD, OUT OF TOUCH WHITE MEN.
I'm convinced that Texas republicans are trying to harm their female populous. They are always on the war path to shut down Planned Parenthood and abortion clinics. One famous instance a Texas woman filibustered an anti-abortion bill for 11 goddamn hours to protect the right to choose for women. She (with the help of the supporting crowd) successfully filibustered it so they couldn't vote it in and close almost all clinics that provide abortion services.
But these are republicans were talking about. They don't know how to be politicians except changing the rules like that fucking twat kid on the playground who changes them when he's losing.
So they held another special meeting to vote upon it. And since its a super duper special no girls allowed meeting, they can bypass certain parts of legislation and just vote it in. And then they smugly proclaim victory over what is essentially just them masturbating in a room together.
You fucking idiots. You were surrounded by hundreds of screaming people that were all opposing you. When that many people show up to stop you, why don't you take any time and try and rationalize why they are doing it? Maybe… wait…maybe, um, MAYBE PEOPLE DON'T WANT THIS.
No, no! You are right! I'm so sorry! I forgot that your personal opinion matters so much more than the opinions of hundreds of people.
Why the fuck do they care about a choice that they don't have to make? I'm pro-choice, but mostly that's because I believe women should have the right over their own bodies. I'm for abortion because I believe there are people who can't or shouldn't have kids.
I'll vote for them to have the choice, every time. Also- I don't have a fucking vagina. So why am I having a say? Men in congress and men in local governments shouldn't have a say unless they are a trained professionals. Doctors and gynecologists. Its an decision that should only really be decided by women who have the appropriate equipment.
If I don't have a race car I do not belong in the Indy 500.
You would have rape victims find it nearly impossible to get abortions. You would have them give birth to evidence of one of the most horrific moments of their lives. You would have them look their rapists in the eyes everyday.
I acknowledge that some women might see it as a new chance to not be defined as a survivor, but a mother.
Until the rapist demands rights over their kids.
The fuck is wrong with you. Republican monsters.
You have to change the rules every time someone follows them. Every time they jump through every stupid hoop you put in front of them you demand more arbitrary things. One you can hear about on Last Week Tonight with John Oliver is that clinics that provide services for women's health need 8 foot hallways. Republicans loudly state that this is for the health and safety of women.
We all know what you are doing. Its the same tactic that small children use to try and get what they want.
What the hell do 8 foot hallways have to do with sexual health? Well its so that two gurneys can pass each other in the hallway! Duh! It's only coincidental that most buildings are retrofitted to be clinics and really have no need for gurneys. A standard hallway is only like 4 feet across. Unless you are at a hospital, most buildings aren't running people around on wheeled beds.
So when they change these rules are arbitrary times, most clinics have a serious issue- the building they set up in doesn't follow these rules and then must shut down. So dozens of clinics have to close their doors. Fewer clinics mean that women all have to use the same one. With that much traffic it becomes difficult for women to get appointments when then they need. Some women and even young girls have had to give up and have a baby, even if it means ruining their lives forever.
Don't worry girls, when you are upset at your situation, just take solace in the fact that the republicans in your government whined and pleaded to have these facilities shut down for your safety and well-being. They denied you affordable healthcare.
Its not just women they seem to hate. Obama passed the Affordable Care Act which- in a nutshell- requires employers to provide healthcare for their employees and sets up a network of healthcare providers that people can choose from.
Essentially Obama is just trying to make having healthcare more accessible for the public.
And the republicans are having none of that shit.
They've opted to shut down the government instead of voting for budgets that provide healthcare for people who have trouble paying the ridiculous premiums. So when GOP budget bills come through they refuse to vote them through, which causes the government to shut down. Hundreds of people out of work. Livelihoods damaged. People dipping into savings. This is what the republicans wanted instead of just working to be an effective government. I mean- they don't care- they get paid regardless.
Of course they claim it has good reason. Its faulty! The website doesn't work! It'll drive up prices! Ever better they argue against GOP budgets because our national debt is so high already we can't borrow against it.
They could've banded together to work towards perfecting this system, but since being a sore loser is much more important to them the reject that notion. Instead of providing us a functional and effective government they'd rather play a devious game of "Fuck you I'm taking my ball and going home!"
I'm not saying democrats or independents are perfect. But it annoys me that it always seems like republicans can't handle the fact that they aren't politically as relevant so they have to continually yell and scream at stuff that is new and confusing. We could work together to find happy mediums but they are playing a stupid game with our lives. Governments should serve and protect the people, not draw lines in the sand and fuck with peoples lives.
I feel better.


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Counselling Online
Counselling Online
Are you interested in undertaking counselling from the comfort of your own home? Perhaps you have a busy life and wonder how you might find the time to attend regular sessions, or your circumstances may make it difficult for you to travel. Does the idea of accessing counselling through your home computer appeal to you?
The good news is that modern technology allows for a much wider range of choice and accessibility to counselling than ever before.
What is Online Counselling?
Online counselling, also called online therapy, differs to traditional counselling in that instead of meeting at the counsellor's rooms, the therapy sessions take place 'online' through a face-to-face video-call (similar to Skype). I use Telebond, a private and secure video-call platform that is easy to use and is designed specifically for clients to meet with professionals online.
How do I start Online Counselling?
- If you are interested in undertaking online therapy with me, or are curious and would like to know more, you can contact me via phone or email using the details given on this website. Simply introduce yourself, giving a few basic details, and I will get back to you as soon as I can.
- Once we have established contact and have agreed between us to move forward to the next stage, I will privately email you two important documents. The first of these is the 'Assessment Form'. This questionnaire allows you to provide me with some of your details and basic information, and will help me understand a bit more about you so I will be prepared for our first session. The second document is the 'Informed Consent'. This contains important information about confidentiality, what to do in case of technological breakdown during a session, and how to ensure good boundary keeping and safe ways of working online. As a data handler registered with the Information Commissioners Office (ICO), I store client records and any other information shared between us in a way that is fully compliant with the General Data Protection Regulation (GDPR). This means your personal details are stored safely, are fully encrypted, and never shared with any third parties.
- Once you have completed and returned these documents to me via email, we can begin to arrange our first session. The system I use for online video sessions is called Telebond. This system is specifically designed for clients to meet professionals by video online in a confidential and easy-to-use way. In plenty of time before the session starts, I will use Telebond to send you an email containing a link inviting you to the session. To access your video-call with me, just click on the link at the beginning of the session time we have agreed on. The email from Telebond will also include a request for payment for the session using Stripe, a secure system for making card payments online (please discuss with me if you would like to arrange an alternate payment system).
It's that easy!
Find out more in Frequently Asked QuestionsLearn more
About my online practice
Counselling online isn't simply a matter of using traditional counselling models on the Internet. Therapists require specific training to be able to work safely and competently online. I am fully certified as an online counsellor through the Online Therapy Institute (OTI), and am a member of the Association for Counselling and Therapy Online (ACTO). I also adhere to the BACP ethical framework for online practice, attend regular supervisory meetings with an online supervisor, and am committed to a program of continuing professional development.
Find out more about me and my counselling styleLearn more