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King of Pride Rock The Lion King Poster 61cm x 91.5cm (24" x 36")
Product Description
1994's The Lion King remains one of the biggest and most popular movies ever made. The musical adventures of Simba was a groundbreaking release from Disney. This epic movie poster features a roaring Simba as he stands on Pride Rock with his friends Timon and Pumbaa, while Zazu hovers gracefully above. With his fathers spirit guiding him through his journey, Simba must battle to take back his prides lands against the evil Scar. This amazing poster is perfect for any film critic or Disney lover to hang on their wall. Hakuna Matata.
- Size: 61cm x 91.5cm (24" x 36")
- Stock ID: 336033-FRAME0
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Our beautiful lives
Are you starting to notice that the light is shifting? More light in the day can really elevate our moods. So often over this winter, with storms raging and darkness falling early, I found myself saying, "We're in the bleak midwinter." But I saw my first snowdrops last week!
We're always evolving.
These beautiful lines from Ecclesiastes say it so well:
To every thing there is a season, and a time to every purpose under the heaven:
a time to be born, and a time to die; a time to plant, and a time to pluck up that which is planted...
a time to weep, and a time to laugh; a time to mourn, and a time to dance...
Sometimes in the winter we get more in touch with the sadness. Have you experienced that? As a therapist I hear so much of grief and loss. It's been said, actually, that all therapy is grief work. Clients don't come in thinking they are "grieving." But there may have been a loss of connection, a loss of internal connection or function -- all part of the human experience.
What can we do about grief or sadness?
1. Recognize it. And name it as grief, so we don't have to be blended with it. Acknowledge and release it.
2. Witness it. I witness my clients' grief, but most importantly, I help them witness their own. Grief can be so painful; but while painful, can also be sublime, even transcendent. And our self energy, which is timeless, can hold it all. Expansion happens when we find out that we can hold what we are experiencing, and it doesn't have to take over. And if it does take over for a time, it's kind of like waves -- we don't have to drown.
3. Release it. It's not a banishment; it's a healing.
The experience of being capable, of carrying what we have, and letting go when it's time to let go, and having the courage to step into a new experience of life enriched and deepened by our grief is quite amazing. It's really, really beautiful, our life.
And here come the snowdrops!

subset: commoncrawl


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Packing for Your Honeymoon | We're Headed To Europe!/
For some of you avid travelers these might seem like no brainers but for me learning all of this was GOLD! My friend Sophia travels the world on practically a daily basis and I'll never forget the time she helped me pack for two weeks in a carry on. It was magical. I'm now putting all of these to use AGAIN because we leave for Ireland, Switzerland and Scotland on THURSDAY!! Hopefully these will help you as you plan for your honeymoon!
1. Lay everything out - I dunno about you, but if I see free space in my bag, I think to myself I must be forgetting something and I need to bring more. NO! Lay everything out first and you won't over pack.
2. Roll Away - This seems so simple, but rolling everything saves so much space. I know. I didn't believe it either until I tried it.
3. Get Separator Bags/Cubes - I actually don't have these but I plan to go out to Target today to find them. If you can pack your shirts in one bag, your dresses in another and your pants in another... you basically have DRAWERS when you get to your destination. My dad used to say "Kaboom!" when my luggage hit the bed and practically exploded from me digging for things and now Chris has adopted the same exclamation. I can't wait to prove them wrong on this trip!!
4. Interchangeable layers - Pinterest is amazzzzzing for this. Also Stitch Fix has been sending me guides on this too! See what different kind of outfits you can build with the same pieces. That'll make it look like you brought more outfits than you did!
5. Remember Your Passport - seems like a gimme, but the last thing you need is to show up ready to go and you forgot the most vital piece of the entire trip on your kitchen counter.
6. Leave Free Space - Normally I say leave half of your suitcase empty, but we're sticking to a carry on, so... not likely. If you're anything like me... the second you find Newbury Street's equivalent that bag starts to fill up pretttttty quickly!
This post is also to tell MJP brides and new 2018 MJP bride hopefuls that we MAY be a little delayed in answering emails. Do you see how that passport up there says 2008? Yep that's the last time I went to Europe and I imagine a few things have changed since then, but I'm heading over there remembering the last time when I had to stop at internet cafes to have any contact with the outside world.
Remember to follow along on Instagram to see all our travels! We aren't going for our honeymoon (obviously :-P), but I figured the packing concept was relatable. We are going to see friends living in Switzerland and we are so excited!!


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How Are Dabs Made?
How are dabs made?
By @MedicalAndy
There are 2 general categories of concentrates—those that were produced with a solvent (which either removes the trichomes by dissolving them or through extreme pressure) and those are were producing using solvent-less methods (which generally removes trichomes through a mechanical process).
This week we will be discussing the main types of solvent concentrates, BHO, CO2, and distillate. Next week we'll discuss the types of solvent-less options, dry sift, bubble hash, and rosin.
Solvent-based concentrates, often known as oil, will always melt. They were produced with a solvent process which removes the plant matter by dissolving the trichome heads together. Post-processing also removes the waxes and lipids of the trichome head.
While the term BHO used to be correct when many extractors simply used canned lighter fluid (compressed butane)—with the popularity of closed-loop systems, many extractors now use a mixture of light hydrocarbons (pentane, butane, propane, etc.) to achieve their specific extraction goals (safety profile, terpene preservation, purging time, etc.).
Hydrocarbon extraction has accurate terpene preservation from the original plant matter, so with high quality starting material it can be a revolutionary way to sample the aromatic compounds that are unique to individual cannabis strains.
Cannabis oil can also be processed with CO2 gas, but many connoisseurs do not like the taste of CO2-produced oil. During processing, the terpenes are separated from the cannabinoids and must be recombined. This process has not yet been perfected and as a result, many CO2 extractions have a similar homogenized taste.
CO2 is favored by many high-volume companies for vape pen or edible production because it can be used to make large batches of oil at once. It is becoming outdated however as customers realize a preference for distilled extracts for their vape pens and edibles. Distilled oil, or distillate (aka "Clear") is BHO or CO2 oil put through an additional refining process to remove additional impurities, activate the oil (turn it from THC-A to THC), and add terpenes if desired. (notice how the oil on the right is much lighter in color than that on the left?)
Cannabis oil can also be made with ethyl alcohol, but this type of oil is not generally used for dabbing. Often known as FECO or "Rick Simpson Oil" this oil is activated and ready for oral ingestion. Like BHO, it has excellent replication of what is present in the original plant material, but alcohol breaks the cell walls of the plant so the extract is much darker. To purge the alcohol, heat is also used, raising the temperature to 190 degrees—which changes the terpene content and also activates the oil (changing THC-A to THC).
So we find that each type of oil tends to have specific uses for which it is best suited. BHO is a good all-around concentrate for dabs. CO2 is a low-cost wholesale option. Distillate is the future for manufactured products.
Remember to check back next week for our discussion of solvent-less options, the least processed methods and an increasing popular option!


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Feline host range of Canine parvovirus: recent emergence of new antigenic types in cats.
Human health and animal welfare continue to be challenged by rapidly evolving pathogens. Although many details about specific host-parasite systems have been reported, our understanding of host range alteration and the evolution of virulence remains rudimentary. We reviewed the evolution of carnivore parvoviruses with particular reference to Canine parvovirus (CPV) infection in cats. These parvoviruses' molecular and phenotypic evolutionary pattern provides an exemplary system to study pathogen-host relationships and the evolution of virulence, both essential factors for understanding newly emerging infectious diseases.
Emergence of Mink enteritis virus and CPV Type 2 (CPV-2)
Infection by Feline parvovirus was thought only to occur in cats (Feline panleukopenia virus, FPLV) or raccoons until the mid-1940s, when a similar disease with a mortality of up to 80% was observed in infected mink kits in Canada (1). The disease caused by the mink agent, named Mink enteritis virus (MEV), was thereafter observed throughout many regions of the world (2). Since MEV was indistinguishable from FPLV by conventional methods such as serum-neutralization assay, MEV isolates have been differentiated from FPLV primarily on the basis of the host from which they are isolated. Using a panel of monoclonal antibodies (MAbs), we now classify FPLV and MEV isolates into three antigenic types, FPLV and MEV type 1 (MEV-1) group, MEV type 2 (MEV-2), and MEV type 3 (2,3) (Figure 1). MEV-1 and MEV-2 have repeatedly been isolated from the mink in the United States, Europe, Japan, and China (2,3; Y. Ikeda and M. Mochizuki, unpub, data).
In the late 1970s, another virus emerged in dogs (4,5). The new virus, designated CPV-2 to distinguish it from an unrelated Canine parvovirus (Canine minute virus), spread around the world within a few months (6,7). CPV-2 spread rapidly, killing thousands of dogs. Polyclonal antibody and in vivo cross-protection studies soon showed that CPV and FPLV were closely related antigenically, while CPV-2 and FPLV were distinguishable from each other when examined with a panel of MAbs (Figure 1). Subsequent extensive genetic analysis of numerous CPV-2, FPLV, and MEV isolates showed that the viruses form two distinct clusters represented by FPLV-type viruses from cats (FPLV), raccoons, and mink (MEV), and by CPV-type viruses from dogs and raccoon dogs. At least 11 conserved nucleotide differences (7 nonsynonymous and 4 synonymous changes) were seen between CPV-2 isolates and FPLV-type viruses in the capsid VP2 sequence; in contrast, CPV and FPLV isolates differ in <2% of their genomic DNA sequences (8) (Figure 2; Table).
Hypotheses on the Ancestor of CPV-2
Retrospective investigations to detect CPV antibodies in sera collected from dogs or related canids showed that the first positive titers were present in European dogs around 1975, while the first positive sera in the USA, Japan, and Australia were seen in early 1978. Various hypotheses on the mechanism of virus evolution in this group have been developed. The most widely accepted hypothesis is the emergence of CPV-2 from a variant of FPLV or of a closely related virus infecting another carnivore, such as mink or foxes (9,10).
Several intriguing observations support the latter hypothesis. First, based on the sequence analyses of the capsid VP-2 and the nonstructural NS1 genes, MEV is closer to CPV-2 than FPLV (9,11). More importantly, the virus isolated from an Arctic fox from Finland (blue fox parvovirus, BFPV) in 1983 appeared to be an intermediate between the FPLV- and CPV-type viruses. BFPV had three synonymous nucleotide changes in the VP2 gene that were specific for the canine sequence (12) (Figure 2), while the fox virus was classified antigenically as typical MEV-2-type (13) (Figure 1). These findings indicate that some animals in the family Canidae, such as mink or foxes, which are susceptible to FPLV-like viruses, might play a role as a reservoir for the ancestor of CPV. Recently, Truyen et al. (14) reported that the intermediate parvovirus sequence from a German red fox was CPV-2-like but had one FPLV-specific nonsynonymous substitution. This suggests that German red foxes could harbor the direct ancestor of CPV, although it remains possible that the intermediate red fox parvovirus emerged from conventional CPV-2 by one point natural mutation (Figure 3).
Emergence of CPV Types 2a and 2b (CPV-2a and CPV-2b)
Since the emergence of CPV-2, two new antigenic types of CPV, designated CPV-2a and CPV-2b, have arisen consecutively. These new virus types have now almost completely replaced CPV-2 viruses as the dominant infectious agents (15) (Figure 3). At least four conserved nonsynonymous substitutions have been observed between CPV-2 and CPV-2a isolates in the VP2 gene (Table). CPV-2b isolates have another two nonsynonymous changes from CPV-2a (Table). Although the exact mechanisms of these evolutions are not clear, the emergence of these new antigenic types of CPV can likely be ascribed to the adaptation of CPV-2-type viruses in dogs. Of interest, each new antigenic type has lost at least one neutralizing epitope compared with the former serotype (16).
Clinical Features of FPLV and CPV in Their Original Hosts
Parvoviruses replicate most efficiently in rapidly dividing cells. Replication is generally lytic, and tissue damage at these sites can be observed (17). Infection with FPLV causes two typical syndromes. When infection occurs in fetuses or very young kittens, a distinct cerebellar ataxia is observed when they become actively ambulatory (18,19). When older kittens are infected, illness characterized by loss of appetite, pyrexia, diarrhea, and leukopenia of both lymphocytes and neutrophils appears (20). On the other hand, two typical syndromes observed in CPV-infected dogs are acute myocarditis in young puppies with a high mortality (21) and hemorrhagic enteritis in older puppies (4,22).
Mortality from FPLV infection is likely to depend on the general condition of the animals before infection. Experimental infection of specific pathogen-free (SPF) or germfree cats with FPLV generally leads to mild diseases (23,24). No or slight intestinal lesions can be observed in infected germfree cats (23), which suggests that the intestinal lesions are caused by secondary bacterial, rather than primary viral, infection.
Host Range of FPLV- and CPV-Type Viruses
The host ranges of FPLV- and CPV-type viruses have been extensively studied in vitro. In general, CPV-type viruses replicate efficiently in feline and canine cell lines, while most FPLV and FPLV-like viruses can replicate efficiently only in feline cells (11,25-27). Subsequent recombination mapping and site-directed mutagenesis experiments have clearly shown that the VP2 gene (including the differences of VP2 residues 93, 103, and 323; Table) is important in controlling canine host range, although a part of the nonstructural NS gene of CPV also participates in FPLV replication in canine cells (27,28). Recently, Ikeda et al. (11) reported a unique FPLV isolate from a domestic cat, which could replicate efficiently in a canine cell line. Interestingly, this isolate was antigenically FPLV-type but had a natural mutation of VP2 residue 323 Asp to CPV-specific Asn, supporting previous site-directed mutagenesis studies. Moreover, FPLV-type virus actually has the potential to acquire canine host range by natural mutation, although phylogenetic analyses indicate that the isolate is unlikely to be a direct ancestor of CPV-2 (11).
The in vivo host ranges of FPLV and CPV seem to be more complicated. FPLV can replicate in feline tissues, such as lymph nodes, thymus, spleen, or intestinal epithelial cells, and high titers of virus are shed in feces. In dogs, however, FPLV replication is seen only in the thymus and bone marrow, not in the gut or mesenteric lymph nodes (26), resulting in no virus shedding in feces (29). In terms of viral evolution, the CPV ancestor had only to gain the ability to infect the gut in order to be shed and spread in the dog population (26). Indeed, Mochizuki et al. (30) report the isolation of FPLV-type virus from diarrheic feces of a clinically diseased dog. Although the reason why the antigenically FPLV-type virus could gain canine host range remains to be determined, the virus possibly had some genetic mutation(s) that did not change its antigenic properties yet rendered the virus able to infect canine gut cells.
Until recently, the feline host range of CPV has been controversial. Goto et al. report that CPV replicates in cats in a pattern similar to FPLV (31); other studies find no detectable CPV replication in any feline tissue (26,32). This discrepancy, however, is due to the antigenic differences of the examined viruses. The virus (Kushiro strain) used in the first study (31) was shown to be CPV-2a (27), whereas the other studies used CPV-2 (26,32). Truyen et al. (33) directly compared the feline host ranges among CPV-2, CPV-2a and CPV-2b and showed efficient replication of both CPV-2a and CPV-2b in experimentally infected cats. CPV-2a and CPV-2b isolates replicate to high titers in lymphoid and intestinal tissues, while the CPV-2 isolate used in this study did not replicate in experimentally infected animals (33).
Feline Host Range of CPV in the Wild
In late 1980s, CPV was first recognized in cats in a natural setting (30). Mochizuki et al. (30) examined eight feline isolates collected during 1987 to 1991 in Japan and demonstrated that three were antigenically and genetically identical to CPV-2a viruses. The first isolation of CPV-2a-type virus from a cat was in 1987 (30). All three CPV-2a-type viruses were isolated from the feces of clinically healthy cats, while the isolates from cats with typical feline panleukopenia were all conventional FPLV-type. Subsequently, CPV-2a and CPV-2b viruses were recognized in cats in the USA (2 of 20 isolates) and Germany (3 of 36 isolates) (33).
Recently, Ikeda et al. (11) examined 18 isolates from unvaccinated cat populations and demonstrated that 15 of the isolates could be classified as CPV-2a- or 2b-related viruses (11). Since carnivore parvoviruses are likely to spread freely and rapidly in the environment when few cats and dogs are vaccinated against FPLV or CPV, CPV-2a/2b-type viruses seem to have more advantages over conventional FPLV in cats under natural conditions. It is therefore possible that CPV-2a/ 2b-type viruses will replace FPLV-type viruses as the dominant infectious agents in domestic cats even in developed countries, where FPLV vaccines are commonly used.
Emergence of New Antigenic Types of CPV (CPV-2c) in Cats
Feline parvoviruses continue to evolve. CPV-2a and 2b have been detected not only from domestic cats but also from wild felids worldwide (11,34). Steinel et al. (34) report the detection of CPV-2b-type viral DNA from one fecal sample of a Namibian farm-raised cheetah and the tissue sections of four captive cheetahs in the United States. CPV-2a-type sequence was also found in the fecal sample of the Siberian tiger from a German zoo (34).
During 1996 to 1997, CPV-2a/2b-related viruses were isolated from Asian small wildcats, leopard cats (Felis bengalensis), in Vietnam and Taiwan (11,35). These viruses were designated as leopard cat parvovirus (LCPV). Three of the six isolates were demonstrated to be new antigenic types of CPV; the other three isolates were essentially identical to CPV-2a or 2b. Subsequently, the new antigenic type viruses were shown to have a natural mutation of VP2 in common (11) (residue 300 Gly to an Asp, Table), which results in remarkable changes of their antigenic properties. The new antigenic type, characterized by the loss of the VP2 epitopes recognized by the reference MAbs A3B10, B6D5, and C1D1, is currently designated as CPV-2c (Figure 1) (11). The reactivity against MAb B4A2, which distinguishes CPV-2b from the other serotypes, further classifies the CPV-2c-type isolates into two serotypes, CPV-2c(a) and CPV-2c(b) (Figure 1).
CPV-2c-type viruses have been isolated only from leopard cats but not from domestic cats in the same area. Since the phylogenetic analysis indicated that CPV-2a and CPV-2b-type viruses were likely to evolve to CPV-2c(a) and CPV-2c(b)-type viruses, respectively, the mutation at the residue 300 Gly to Asp is probably ascribed to the adaptation of CPV-2a/2b-type viruses to leopard cats. Similar to the emergence of CPV-2a and CPV-2b, CPV-2c has lost neutralizing epitopes compared with the former serotypes, CPV-2a and 2b.
Virulence of CPV-2a and -2b in Cats
The pathogenicity of CPV-2a and 2b in cats remains debatable. Mochizuki et al. reported the isolation of CPV-2a from a cat manifesting clinical signs of feline panleukopenia (36). The detection of CPV-2ad2b-type DNA sequences from the cheetahs with chronic diarrhea and enteritis or the tiger with anorexia and diarrhea (34) strongly suggests CPV-2a's and CPV-2b's pathogenic potential in large felids. In sharp contrast, recent studies using SPF cats experimentally infected with CPV-2a or CPV-2b showed no or slight illness, such as mild lymphopenia, in the infected animals (31,33,37,38). Moreover, the fact that many CPV-2a- and CPV-2b-type viruses were isolated from clinically healthy cats (11,30,35,39) seems to indicate their relatively low pathogenicity.
At present, this discrepancy remains to be resolved. Note, however, that the experimental infection of SPF cats with FPLV generally leads to mild disease (23,24). In this regard, the study reported by Goto et al. (31) is intriguing. These researchers compared the clinical signs of five SPF and four conventional cats experimentally infected with CPV-2a. The infected five SPF cats showed neither clinical signs nor leukopenia through the observation period, while depression (four cases), vomiting (two), diarrhea (one), and severe leukopenia (four) were observed in the four conventional cats. One cat died 4 days after infection (31). These data indicate that the illness from CPV-2a/2b infection highly depends on the general condition of the cats before infection.
Pathogenic Potential of CPV-2c
Since feline parvoviruses shed in the feces survive in the environment for up to several months, a fecal-oral route is considered to be the predominant means of their transmission. Although CPV-2c-type viruses have been isolated only from leopard cats (13,38), the new serotype viruses will likely spread to domestic cat and dog populations. Nakamura et al. (38) compared the virulence between FPLV, CPV-2a, and CPV-2c in SPF cats. In this experiment, diverse pathogenicity of the CPV-2a for individual cats was observed. One cat had symptoms frequently associated with parvovirus infection, including leukopenia and diarrhea; the other cats remained asymptomatic. One cat showed no evidence of infection. In contrast to the results obtained with CPV-2a-inoculated animals, all cats inoculated with CPV-2c developed diseases, although the symptoms were relatively milder than those observed in FPLV-inoculated cats. These data indicate that CPV-2c and CPV-2a both have the potential to cause diseases in cats, with some variations of symptoms. CPV-2c appears to be more infectious in cats than CPV-2a and to induce a higher frequency of disease than CPV-2a, although the numbers of cats tested in the experiment were small. Since CPV-2a did not produce any clinical symptoms in the infected SPF cats, yet demonstrated strong virulence in the infected conventional cats (31), it is also possible that CPV-2c infection results in severe illness in conventional cats.
The virulence of CPV-2c in dogs remains to be determined. The most probable hypothesis is that the new antigenic viruses can infect dogs and cause some illness, as seen in the emergence of CPV-2a and 2b in 1980s. However, the CPV-2c-type viruses may also have lost their canine host range. The latter hypothesis is based on the fact that CPV-2, which is believed to have emerged from FPLV-related viruses, fails to infect cats. The pathogenic potential of CPV-2c in dogs needs to be addressed (Figure 3).
Persistent Infection of CPV in Cats
Animals that recover from feline parvovirus infection retain high specific neutralization antibodies and show no virus shedding. Although isolation of FPLV from apparently healthy cats has been reported, feline parvoviruses are generally believed to be completely eliminated from recovered animals.
As mentioned, CPV-type viruses have been isolated from the fecal samples of apparently healthy cats (30). Moreover, many CPV-type viruses were isolated from the peripheral blood mononuclear cells (PBMC) of cats with high specific neutralizing antibodies (11,35,39), suggesting that CPV could persistently infect cats irrespective of the presence of the neutralizing antibodies. Although precise mechanisms of the persistent infection of CPV remain to be determined, PBMC probably play a role as a reservoir for the viruses. If one assumes that CPV actually infects cats persistently, examination will be needed to determine whether sporadic shedding of the virus occurs in recovered cats.
The Efficacy of Conventional FPLV Vaccines against CPV
The study of an attenuated live FPLV vaccine for CPV-2b infection has shown that vaccinated SPF cats are protected from challenge with CPV-2b at 2 weeks after vaccination (37). A cross-neutralization study of the antibodies induced by an inactivated FPLV vaccine demonstrated that the vaccinated cats actually develop neutralizing antibodies against CPV-2a, 2b, and 2c as well as FPLV (40). These data indicate that commercially available FPLV vaccines can be used for protection against CPVs, at least in the short term. However, antibody titers induced by a FPLV vaccine are significantly lower against CPVs than FPLV (40). Indeed, CPV infection was observed in the cheetahs vaccinated with a killed FPLV vaccine (34). We therefore suggest that FPLV vaccines are not always sufficient to protect cats from CPV infection in the long term. Steinel et al. (34) have proposed the need for inactivated vaccines that use CPV-2a or 2b for cats. CPV-2a/2b-based vaccines are expected to protect cats more efficiently from CPV infection than conventional FPLV vaccines. Recently, Nakamura et al. reported that cats experimentally infected with CPV-2a develop high titers of neutralizing antibodies against CPV-2a and 2b but show relatively low titers against FPLV (40). Thus, like FPLV vaccines for CPV infection, CPV-2a/2b-based vaccines may be less efficient for FPLV infection, which would be a major concern. Interestingly, CPV-2c-infected cats showed similar neutralization antibody titers against FPLV, CPV-2a, and 2b as well as CPV-2c (40). An inactivated CPV-2c-based vaccine for cats could be a promising vaccine candidate against both CPV and FPLV infection.
Problems with the Current Parvovirus Nomenclature
Finally, we point out problems with the current nomenclature of carnivore paroviruses, including FPLV, MEV, and CPV. As we mentioned, all carnivore parvovirus isolates are known to be genetically closely related to each other; interspecies transmissions readily occur among carnivores. On the other hand, field isolates have been distinguished on the basis of the host from which they are isolated. According to this system, CPV-2a- and 2b-type isolates from cats should be designated as FPLV types 2 and 3, even though they are essentially indistinguishable from CPVs from dogs. To solve this problem, a new nomenclature is needed. Naming any field carnivore isolate as feline parvovirus or carnivore parvovirus, irrespective of their original hosts, and using the names such as FPLV and CPV-2a to distinguish antigenic or genetic properties would be more appropriate.
The evolutionary pattern of FPLV in cats differs from that of CPV in dogs. Since FPLV is in evolutionary stasis in cats, FPLV mainly evolves with random genetic drift (9). In contrast, CPV appears to evolve in dogs under certain positive selection on the VP2 protein (9), which may be because of its short history in dogs. How CPVs are evolving in cats remains relatively obscure. Since CPV-2a and 2b are likely to act as newly emerging parasites in cats, some cat-specific positive selection(s), such as relative in vivo fitness and immune surveillance, could operate as a driving force of CPV evolution. The emergence of CPV-2c in leopard cats is a good example of the evolution of CPV in new hosts. Similarly, since specific antibodies against CPV have been detected in a wide range of wild animals, such as large felids, wildcats, civets, otters, and even bears, such interspecies transmissions probably result in accelerated emergence of other new antigenic types of CPVs because of the new host-specific positive selection.
Elucidating how feline parvoviruses are evolving and [low newly emerging variants behave may help to prevent a possible outbreak of the new variant. Assuming that a new virulent CPV variant emerges in cats in the future, what can we expect? Fortunately, the newly emerging variant will not likely cause rapid outbreaks in cats or dogs, since FPLV and CPV-2a/2b have been actively circulating in carnivore populations. Commercially available FPLV or CPV-2-based vaccines might also protect animals from the new virus infection. However, if the new virus gains wider host ranges, deadly outbreaks could be observed, as when CPV-2 emerged in dogs. In any case, recent isolates need to be investigated to anticipate and assess the risk caused by newly emerging viruses.
Table. Phylogenetically informative amino acid sequences in the VP2 gene Virus 80 87 93 103 232 297 FPLV/MEV-1 Lys Met Lys Val Val Ser MEV-2/BFPV Lys Met Lys Val Val Ser CPV-2 Arg Met Asn Ala Ile Ser CPV-2a Arg Leu Asn Ala Ile Ser/Ala CPV-2b Arg Leu Asn Ala Ile Ser/Ala CPV-2c(a) Arg Leu Asn Ala Ile Ala CPV-2c(b) Arg Leu Asn Ala Ile Ala Virus 300 305 323 426 555 564 568 FPLV/MEV-1 Ala Asp Asp Asn Val Asn Ala MEV-2/BFPV Val Asp Asp Asn Val Asn Ala CPV-2 Ala Asp Asn Asn Val Ser Gly CPV-2a Gly Tyr Asn Asn Ile Ser Gly CPV-2b Gly Tyr Asn Asp Val Ser Gly CPV-2c(a) Asp Tyr Asn Asn Val Ser Gly CPV-2c(b) Asp Tyr Asn Asp Val Ser Gly FPLV = Feline panleukopenia virus; MEV = Mink enteritis virus; BFPV = blue fox parvovirus; CPV = Canine parvovirus.
We thank C. R. Parrish for providing monoclonal antibodies (MAbs) A3B10, B6D5, B2G11, B4E1, A4E3, C1D1, and B4A2; and M. Horiuchi for providing MAb P2-215. We thank Blair L. Strang for extensive comments and suggestions for improving the manuscript.
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(2.) Parrish CR, Gorham JR, Schwartz TM, Carmichael LE. Characterization of antigenic variation among mink enteritis virus isolates. Am J Vet Res 1984;45:2591-9.
(3.) Parrish CR, Carmichael LE. Antigenic structure and variation of canine parvovirus type-2, feline panleukopenia virus, and mink enteritis virus. Virology 1983;129:401-14.
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(5.) Kelly WR. An enteric disease of dogs resembling feline panleucopaenia. Aust Vet J 1978;54:593.
(6.) Gumbrell RC. Parvovirus infection in dogs. N Z Vet J 1979;27:113.
(7.) Kelly WR, Atwell RB. Diffuse subacute myocarditis of possible viral aetiology: a cause of sudden death in pups. Aust Vet J 1979;55:36-7.
(8.) Kariatsumari T, Horiuchi M, Hama E, Yaguchi K, Ishigurio N, Goto H, Shinagawa M. Construction and nucleotide sequence analysis of an infectious DNA clone of the autonomous parvovirus, mink enteritis virus. J Gen Virol 1991;72:867-75.
(9.) Horiuchi M, Yamaguchi Y, Gojobori T, Mochizuki M, Nagasawa H, Toyoda Y, et al. Differences in the evolutionary pattern of feline panleukopenia virus and canine parvovirus. Virology 1998;249:440-52.
(10.) Truyen U, Geissler K, Parrish CR, Hermanns W, Siegl G. No evidence for a role of modified live virus vaccines in the emergence of canine parvovirus. J Gen Virol 1998;79:1153-8.
(11.) Ikeda Y, Mochizuki M, Naito R, Nakamura K, Miyazawa T, Mikami T, Takahashi E. Predominance of canine parvovirus (CPV) in unvaccinated cat populations and emergence of new antigenic types of CPVs in cats. Virology 2000;278:13-9.
(12.) Truyen U, Gruenberg A, Chang SF, Obermaier B, Veijalainen P, Parrish CR. Evolution of the feline-subgroup parvoviruses and the control of canine host range in vivo. J Virol 1995;69:4702-10.
(13.) Veijalainen P. Characterization of biological and antigenic properties of raccoon dog and blue fox parvoviruses: a monoclonal antibody study. Vet Microbiol 1988;16:219-30.
(14.) Truyen U, Muller T, Heidrich R, Tackmann K, Carmichael LE. Survey on viral pathogens in wild red foxes (Vulpes vulpes) in Germany with emphasis on parvoviruses and analysis of a DNA sequence from a red fox parvovirus. Epidemiol Infect 1998;121:433-40.
(15.) Parrish CR, O'Connell PH, Everman JF, Carmichael LE. Natural variation of canine parvovirus. Science 1985;230:1046-8.
(16.) Strassheim ML, Gruenberg A, Veijalainen P, Sgro JY, Parrish CR. Two dominant neutralizing antigenic determinants of canine parvovirus are found on the threefold spike of the virus capsid. Virology 1994;198:175-84.
(17.) Carlson JH, Scott FW. Feline panleukopenia. II. The relationship of intestinal mucosal cell proliferation rates to viral infection and development of lesions. Vet Pathol 1977;14:173-81.
(18.) Johnson RH, Margolis G, Kilham L. Identity of feline ataxia virus with feline panleucopenia virus. Nature 1967;214:175-7.
(19.) Kilham L, Margolis G, Colby ED. Cerebellar ataxia and its congenital transmission in cats by feline panleukopenia virus. J Am Vet Med Assoc 1971;158:888.
(20.) Carpenter JL. Feline panleukopenia: clinical signs and differential diagnosis. J Am Vet Med Assoc 1971;158:857-9.
(21.) Robinson WF, Wilcox GE, Flower RL, Smith JR. Evidence for a parovirus as the aetiologic agent in the myocarditis of puppies. Aust Vet J 1979;55:294-5.
(22.) Robinson WF, Wilcox GE, Flower RL. Canine parvovirus disease: experimental reproduction of the enteric form with a parvovirus isolated from a case of myocarditis. Vet Pathol 1980;17:589-99.
(23.) Carlson JH, Scott FW, Duncan JR. Feline panleukopenia. I. Pathogenesis in germfree and specific pathogen-free cats. Vet Pathol 1977;14:79-88.
(24.) Goto H, Hosokawa S, Ichijo S, Shimizu K, Morohoshi Y, Nakano K. Experimental infection of feline panleukopenia virus in specific pathogen-free cats. Nippon Juigaku Zasshi 1983;45:109-12.
(25.) Ikeda Y, Shinozuka J, Miyazawa T, Kurosawa K, Izumiya Y, Nishimura Y, et al. Apoptosis in feline panleukopenia virus-infected lymphocytes. J Virol 1998;72:6932-6.
(26.) Truyen U, Parrish CR. Canine and feline host ranges of canine parvovirus and feline panleukopenia virus: distinct host cell tropisms of each virus in vitro and in vivo. J Virol 1992;66:5399-408.
(27.) Horiuchi M, Goto H, Ishiguro N, Shinagawa M. Mapping of determinants of the host range for canine cells in the genome of canine parvovirus using canine parvovirus/mink enteritis virus chimeric viruses. J Gen Virol 1994;75:1319-28.
(28.) Chang SF, Sgro JY, Parrish CR. Multiple amino acids in the capsid structure of canine parvovirus co-ordinately determine the canine host range and specific antigenic and hemagglutination properties. J Virol 1992;66:6858-67.
(29.) Pollock RV, Carmichael LE. Use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus. Am J Vet Res 1983;44:169-75.
(30.) Mochizuki M, Harasawa R, Nakatani H. Antigenic and genomic variabilities among recently prevalent parvoviruses of canine and feline origin in Japan. Vet Microbiol 1993;38:1-10.
(31.) Goto H, Hirano T, Uchida E, Watanabe K, Shinagawa M, Ichijo S, et al. Comparative studies of physicochemical and biological properties between canine parvovirus and feline panleukopenia virus. Nippon Juigaku Zasshi 1984;46:519-26.
(32.) Truyen U, Agbandje M, Parrish CR. Characterization of the feline host range and a specific epitope of feline panleukopenia virus. Virology 1994;200:494-503.
(33.) Truyen U, Evermann JF, Vieler E, Parrish CR. Evolution of canine parvovirus involved loss and gain of feline host range. Virology 1996;215:186-9.
(34.) Steinel A, Munson L, van Vuuren M, Truyen U. Genetic characterization of feline parvovirus sequences from various carnivores. J Gen Virol 2000;81:345-50.
(35.) Ikeda Y, Miyazawa T, Nakamura K, Naito R, Inoshima Y, Tung KC, et al. Serosurvey for selected virus infections of wild carnivores in Taiwan and Vietnam. J Wildl Dis 1999;35:578-81.
(36.) Mochizuki M, Horiuchi M, Hiragi H, San Gabriel MC, Yasuda N, Uno T. Isolation of canine parvovirus from a cat manifesting clinical signs of feline panleukopenia. J Clin Microbiol 1996;34:2101-5.
(37.) Chalmers WS, Truyen U, Greenwood NM, Baxendale W. Efficacy of feline panleucopenia vaccine to prevent infection with an isolate of CPV2b obtained from a cat. Vet Microbiol 1999;69:41-5.
(38.) Nakamura K, Sakamoto M, Ikeda Y, Sato E, Kawakami K, Miyazawa T, et al. Pathogenic potential of canine parovirus types 2a and 2c in domestic cats. Clin Diagn Lab Immunol 2001;8:663-8.
(39.) Miyazawa T, Ikeda Y, Nakamura K, Naito R, Mochizuki M, Tohya Y, et al. Isolation of feline parvovirus from peripheral blood mononuclear cells of cats in northern Vietnam. Microbiol Immunol 1999;43:609-12.
(40.) Nakamura K, Ikeda Y, Miyazawa T, Tohya Y, Takahashi E, Mochizuki M. Characterization of cross reactivity of virus neutralizing antibodies induced by feline panleukopenia virus and canine parvovirus. Res Vet Sci 2001 ;71:219-22.
Dr. Ikeda is a postdoctoral fellow in the Department of Immunology, University of London, United Kingdom. He has a research background in veterinary virology and current interests in the application of genetically modified dendritic cells as therapeutic vaccines as well as the host range restriction of infectious diseases.
Address for correspondence: Yasuhiro Ikeda, Department of Immunology and Molecular Pathology, Windeyer Institute of Medical Sciences, University College London, 46 Cleveland Street, London W1T 4JF, UK; fax: 0207-679-9357; e-mail: email@example.com
Yasuhiro Ikeda, * ([dagger]) Kazuya Nakamura, ([dagger]) Takayuki Miyazawa, ([dagger]) Yukinobu Tohya, ([dagger]) Eiji Takahashi, ([dagger]) and Masami Mochizuki ([double dagger])
* University College London, London, United Kingdom; ([dagger]) University of Tokyo, Bunkyo-ku, Tokyo, Japan; and ([double dagger]) Kyoritsu Shoji Corporation, Chiyoda-ku, Tokyo, Japan
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Hunt + Gather is centered in the Highland Park community + features a market full of local artists + designers with delicious eats + drinks! Home goods, clothing, jewelry + crafts will be present. If you're in the hood go check it out + support local!
Time: TBD
Cost: FREE


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Nature's Magic : Cowl Pattern
Nature's Magic : Cowl Pattern
**Contact Jenn Sheelen for custom orders of finished items**
This cowl is a lovely and delicate knit that makes you feel like you're sitting in the woods of a magical land as you knit it. The pattern has subtle traveling leaves that border a hint of pine cones. You can almost smell the pine of the trees and hear the wind whistling through the leaves. It's a whimsical knit that is irresistible to make in fall-like colors or naturals for a softer look. This cowl is perfect to go casual or add to an outfit to dress it up as well as give you a bit of warmth.
Instructions have been written out as well as charted for the knitters preference.
Suggested Yarn : Fingering Weight
Gauge: 26 stitches and 38 rows = 4 inches in stockinette stitch
Needle Size : US 2 - 2.75 mm, US 5 - 3.75 mm
Yardage : 200-220 yards (183-201 m)
Check out the patterns for the matching hat and mitts as well!


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Two performances by Cantori New York. Program features US premiere of Paroles contre l'oubli by Thierry Machuel and includes a rare revival of Jacob Avshalomov's Tom O'Bedlam plus music by Brahms. More at cantorinewyork.com
Back to All Events
Earlier Event: October 30Juilliard Vocal Arts - Benjamin Britten's The Burning Fiery Furnace
Later Event: November 19The Prince Edward Island Symphony - Canada 150


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Opening day is May 9th!
Show your support for local food growers & producers.
In May, we'll have local greens, spring veggies, plant starts, fresh dinner options, baked goods, meat, sweet treats & more!
2 - 7 pm
May 9th - October 24th!
Location update! The market will continue on the parking lot where we've been the past decade. It's true, our lot has a new owner and there are plans for future development, but we'll still be kicking off the season at our current location.
So join us in 2018 at the corner of SE 14th and SE Bybee Blvd.
Calling high school student looking to build skill to check out the PDX Vendorship Program.
Learn more or apply to this free 8 week program!


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Elder law services are in higher demand today with shifting demographics. Some kind of legal help will likely be needed by all of us at some point in our later years.
Professional legal services for older people is an important societal need. Consider some elder law facts. Older people face more issues such as:
- Age discrimination
- Obtaining federal benefits such as Social Security and Supplemental Security Income
- Appeals from denial of Medicare benefits
- Establishing Medicaid eligibility
- Housing problems
- Mental incapacity and guardianship
- Abusive or poor quality home health or nursing home care
Elder Law services encompass many facets of the law including estate planning, property management, health care planning and public benefits. The attorneys at Martin, Lord & Osman who practice Elder Law often go beyond traditional legal issues. By advice, referral, or direct assistance we strive to help our clients address problems in securing health and social services and work closely with other professionals such as health care providers.


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Dear European PDGA members,
Recently, we sent you an invitation via email to participate in a survey.
This survey invitation has been sent to every current (per 31/12/17) PDGA member in Europe, and was sent to everyone's email address known to the PDGA. *
* In case you did not receive the invitation to this survey, check your spam filters and make sure you have whitelisted pdga-europe.com.
If no email was delivered to your mailbox, please send an email to office *at* pdga-europe.com and we will look into it, and edit your email address in the database if need be.
Please take the time to complete this short but important survey. You will find the link to the survey in the email.
PDGA Europe is now becoming its own self governing and self responsible division of PDGA Global, with its own office in Europe. To this end PDGA Europe will be assuming many of the roles and responsibilities previously held by PDGA headquarters in USA. Among the largest of these responsibilities is the fulfilment of memberships, which refers to the mailed package and electronic communications a member receives after joining the PDGA or renewing their PDGA membership.
The aim of this survey is to determine the most cost and labour efficient method(s) in which PDGA Europe can provide fulfilment services including which items you as a member most want to receive, and how PDGA Europe should deliver them to you. Your answers will also enable PDGA Europe to decide whether to use the same system for all countries or to use different systems for the different countries.
Thank you for your time.


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Been awhile since I've blogged. Last week was fall break for Jonathan's school and the beginning of this week I was in Birmingham hosting a couple who are possibly starting a new church there in 2015. If you didn't know this, I'm the regional director for the Acts 29 church planting network, which includes Georgia and Alabama, as well as Mississippi, Arkansas and Tennessee. One reason I bring that up is because through my role in A29, our church has a direct role in starting new churches all over the South. You have been generous in allowing me to take a day a week to help men build out churches like ours from Little Rock to Savannah, from Mobile to Nashville. Speaking of generosity, we've had a great response to the opportunity we put in front of you last Sunday to help us end the year well financially. If you weren't there on Sunday and are part of our church, you should receive an email later today that will catch you up to speed with all the details, but what we all had to wrestle with last week was Jesus' insistence in Luke 12:13-21 that if we're part of his family, then we'll be generous people - giving our money regularly, sacrificially and cheerfully to make Jesus non-ignorable (you can listen to the sermon here).
This Sunday, Jesus is going to keep talking about money in Luke 12:22-34 as we wrestle with the question, 'how do we become generous?' As we listen to Jesus, it shouldn't surprise us if what Jesus is asking us to give feels impossible. It is, after all, a sacrifice. And that doesn't sound like a whole lot of fun. So we have a real dilemma on our hands - do we follow Jesus with our money or do we hold on to it because we think God understands our situation and how impossible it would be if we gave what Jesus is telling us to give.
Inviting you to a Sunday like this feels a smidge weird. For some of you, talking about money makes you very uncomfortable. No doubt some of you are frustrated that the pastor is talking about money again. That's why I want to keep this in front of you: are you following Jesus with your money? That's what matters to me. So show up on Sunday and bring a friend; you and I need to hear the God of the universe show us how much he loves us.
Much Love,
PS - Keep inviting family and friends to our Legacy Weekend on November 3-4. We have details coming about our BBQ and bonfire on Saturday night, November 3rd. And we're looking to pack out the floor of the Classic Center Theater at 10am on Sunday, November 4th. Only way we do that is if you show up and bring folk with you to hear our story as a church and to meet with Jesus!


text: The VCSU Concert Choir is a non-auditioned ensemble of 60-70 members from across the student body. The choir performs two concerts per semester and tours on a regular basis. In addition to concerts in North Dakota and Minnesota, the ensemble has performed internationally in Mexico, England, the Netherlands, Austria, and the Czech Republic. The choir performs a variety of literature, including Renaissance motets, American folk songs and spirituals, contemporary choral works, and large works with orchestra. In addition to concerts and tours, the choir participates in a yearly retreat, fundraising and organizational activities, and represents the campus at special events. For more information, contact Dr. Christopher Redfearn at firstname.lastname@example.com.


text: SAN FRANCISCO (MarketWatch) -- Alderwoods Group Inc. AWGI, +0.00% Wednesday evening said its shareholders have voted to adopt the plan for Service Corporation International's SCI, +1.76% proposed $856 million acquisition of Alderwoods. The deal between the two funeral services providers is contingent on completion of a regulatory antitrust review. Alderwoods sees the deal closing by the end of 2006.


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The band's playlist consists of five decades of dance hits that will get the audience out of their seats and onto the dance floor. Whether it is soul, R&B, pop, classics, or jazz, the band can play it all. Tell us what vibe you want and we'll tailor a playlist just for your special event.
Music Samples


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The new Mondaine SBB evo2 has been subtly refined for contemporary life. Its slightly rounded shape with an almost seamless transition to its case back has been ergonomically designed for ultimate comfort. Refined case lugs and a new functional crown sit in perfect proportion throughout the whole collection for precise balance.
Why does the second hand stop after each minute for two seconds? A unique feature of the Swiss Railway (SBB) Clock to ensure smooth and absolutely precise departures of Swiss trains on the full minute for the last 70 years. An ingenious design by a Swiss engineer employed by SBB, that ensured train punctuality would become a visible concept across the globe. A timepiece that ticks off the minute at 58 seconds continues to charm and intrigue; Swiss watchmaker Mondaine has incorporated this unique motion within its Mondaine - SBB/Official Swiss Railway Watch.
Mondaine asked designer Martin Drechsel, to come up with a design for the new watch. As a tribute to its industrial background he framed the stainless steel case with two matte-brushed stainless steel braces, fading to the horns to fit the strap. The crown has been built as a functional switch for easy time setting of the new and unique movement, which was developed by Mondaine, to ensure clear visibility of the 12 o'clock second stop and iconic dial. The crystal is made from scratch resistant anti-reflective coated sapphire glass.
Model number: MSE.35110.SM
Movement (manufacture. Ref.): RONDA 503
Movement (type): Quartz
Case size/diameter (mm): 35.00
Case material: Stainless steel brushed
Case back: Pressed caseback
Crown: Regular Gasket
Crystal/Glass material: Sapphire crystal
Water resistance (m/ft/atm): 30/100/3
Strap/Bracelet material: Stainless steel brushed
Strap width at lug (mm): 18.00
Origin: Swiss Made


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The US Supreme Court held in Life Techs. Corp. v. Promega Corp., Slip No. 14-1538 (Feb. 22, 2017) that supplying a single component of a multi-component invention manufactured abroad does not give rise to patent infringement liability under section 271(f)(1) because a single component cannot constitute a substantial portion of an invention's components for section 271(f)(1) purposes.
Life Technologies Corporation (Life Tech) manufactures and sells genetic testing kits worldwide. Life Tech manufactured all but one component of its kits in the United Kingdom. The one component not made in the United Kingdom, Taq polymerase, was manufactured in the United States. Life Tech shipped the Taq polymerase to its United Kingdom facility, where it was combined with the other four components of the kits.1
Promega filed a patent infringement action against Life Tech alleging that supplying Taq polymerase from the United States to Life Tech's United Kingdom manufacturing facilities triggered liability under section 271(f)(1), which imposes liability for supplying "all or a substantial portion of the components of a patented invention." The jury returned a verdict for Promega, finding Life Tech liable for manufacturing Taq polymerase in the United States and shipping the Taq polymerase to a Life Tech facility in the United Kingdom where the Taq polymerase was combined with four other components to form the patented invention. The district court, however, overturned the jury verdict. The district court ruled that section 271(f)(1) does not encompass the supply of a single component of a multi-component invention and that Promega's evidence at trial "showed at most that one component of all of the accused products, [the Taq] polymerase, was supplied from the United States."
On appeal, the US Court of Appeals for the Federal Circuit reinstated the jury verdict. The Federal Circuit held that the sale of a single component can be sufficient to meet the 35 U.S.C. § 271(f) threshold requirement of supplying "all or a substantial portion of the components of a patented invention," reasoning that "the ordinary meaning of 'substantial portion' suggests that a single important or essential component can be a 'substantial portion of the components' of a patented invention." The Federal Circuit noted that Taq polymerase is an essential component of a genetic testing kit because the genetic testing kit is inoperable without Taq polymerase (which is required for polymerase chain reaction to occur). Therefore Taq polymerase constitutes a substantial portion of the patented invention under section 271(f)(1).
The Supreme Court granted certiorari on the limited question of:
Whether the Federal Circuit erred in holding that supplying a single, commodity component of a multi-component invention from the United States is an infringing act under 35 U.S.C. § 271(f)(1), exposing the manufacturer to liability for all worldwide sales.
The Statute at Issue
35 U.S.C. § 271(f)(1) reads as follows:
Whoever without authority supplies or causes to be supplied in or from the United States all or a substantial portion of the components of a patented invention, where such components are uncombined in whole or in part, in such manner as to actively induce the combination of such components outside of the United States in a manner that would infringe the patent if such combination occurred within the United States, shall be liable as an infringer.
By way of background, section 271(f)(1) was enacted to close a loophole in patent law uncovered in Deepsouth Packing Co. v. Laitram Corp., 406 U.S. 518 (1972). In that case, the Supreme Court determined that, under patent law as it existed at the time, a manufacturer was not liable for patent infringement when the manufacturer made the components of an infringing product in the United States and then exported the parts to foreign buyers that assembled and used the completed machines abroad. Deepsouth, 406 U.S. at 527; see also Promega Corp. v. Life Techs. Corp., 773 F.3d 1338 (2014).
Supreme Court Decision
The Supreme Court reversed the Federal Circuit, ruling that the supply of a single component of a multi-component invention cannot be an infringing act under section 271(f)(1).
In reaching its decision, the Supreme Court first addressed whether the term "substantial," as used in section 271(f)(1), refers to qualitative importance or to a quantitatively large size. Life Tech argued that the text of section 271(f)(1) establishes a quantitative threshold, and that the threshold must be greater than one. Promega defended the Federal Circuit's reading of the statute, arguing that a "substantial portion" of the components includes a single component if that component is sufficiently important to the invention.
The Court started by acknowledging that "substantial," as it is commonly understood, may refer either to qualitative importance or to a quantitatively large size. However, the context in which "substantial" appears in section 271(f)(1) led the Court to find that "substantial" has a quantitative meaning in the statute. Notably, certain other terms in section 271(f)(1), such as "all" and "portion," convey a quantitative meaning. Additionally, statutory syntax also suggested a quantitative meaning.
After ruling that the term "substantial portion" refers to a quantitative measurement, the Court then addressed whether a single component can ever constitute a "substantial portion" that would trigger liability under section 271(f)(1). In answering no to this question, the Court concluded that the text, context and structure of section 271(f) made clear that when Congress said "components," plural, it meant plural, and when it said "component," singular, it meant singular. The Court explained that reading section 271(f)(1) to impose liability for a single component renders section 271(f)(2) superfluous because this section specifically refers to a single component "especially made or especially adapted for use in the invention." In a concurring opinion, Justice Samuel Alito noted that, while the Court's decision establishes that more than one component is necessary to constitute a substantial portion of an invention's components for section 271(f)(1) purposes, the decision does not address how much more.
Companies that use global manufacturing in which some of the components emanate from the US should consider freedom-to-operate strategies that minimize not only the qualitative nature of the exported components, but also their quantitative contribution toward a patented multi-component product. Exportation of a single important component is insufficient to invoke liability under section 271(f)(1) for offshore manufacturing. 1 The kits contained at least the following additional components: (1) a primer mix; (2) a PCR reaction mix including nucleotides; (3) a buffer solution; and (4) control DNA.


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Like full gyms and snowed-out school days, January brings a slog of "top trends" pieces for content marketers. The obnoxious things is that these predictions tend to not differ year-to-year–and they tend to inform no strategy and provide no insight to the lay-content-writer (or lay-[industry]-person).
Let's break out of that habit.
I've taken the time to scour the most cutting edge research in content marketing. I'm not going to tell you that video is going to be big–it's already big, or that Instagram will help you sell more boat parts (let's keep it to B2B, 'k?). Instead, I'm going to stick with new ideas, cutting-edge technology, and some guesses that are so advanced that they might be wrong for 2017… but right for 2018.
With no further ado, I bring you: the top 5 B2B content marketing trends for 2017.
1. Content marketers will finally get truly predictive analytics
Let's be real: Google Analytics and Google Analytics 360 (formerly Google Analytics Premium) are both exceptional products. They'll tell you exactly the number of people who visited your site and, if they didn't go through search (ugh), exactly how they got there, especially if you're savvy with UTM tags. But chopping up Analytics–or competitors like Gridsum in China or Kissmetrics–is still tough to get predictive insights.
In other words, these tools, up until this year, have been really great at telling you what has happened, but not what's going to happen.
And that's about to change.
Just like there are a bajillion B2B content marketing trends pieces, there are also a ton of business intelligence and machine learning articles coming out. What few are talking about is the intersection of the two.
One guy who's ahead of the game has already coined "content intelligence" to talk about content meets BI. Jordan Koene of Searchmetrics explains:
Fundamentally, content intelligence allows content marketers to get more agile with their data. Sure, everyone wants traffic, but if you're aiming to optimize getting Latinas who are 18- to 34- years-old on mobile before noon on Tuesdays, you're going to need a better tool than what Google provides.
Get ready to upgrade your content analytics platform for more customizable reports and predictive analytics.
2. Machine learning will inform content idea generation
Stemming off "better analytics," 2017 is going to bring a whole host of cool, new ways of developing topics for your readers.
It has always been a B2B content marketing trend to tailor to your audience–at least, that should have always been a trend. But now tools are available to do that better.
Imagine this: there are soon to be tools made available that can
- Tell you your audience's reading level
- Tell you what kind of emotional language they like and dislike
- Tell you when your audience will likely be on what screen
Of course, artificial intelligence will never replace content marketers, but it might replace content data analysts in the next five years. Until then, B2B content marketers can start to pull from their insights this year.
3. Multimedia content will become a lot more common and expected, even in B2B
Check out this gorgeous report from CNN called, "Plastic island: How our trash is destroying paradise."
There are a few trends at play here–CNN has chosen to use creative writing in their reporting, embedded high-quality video, and ditched pagination.
As internet marketers, we still see online text as an extension of books–some sites, like Forbes, even paginate their articles, but others save the margins for adds (like a newspaper), and even more create distinct living places for video, graphics, and words.
This CNN article demonstrates the future of online content–and, B2B marketers take note, it's going to happen fast. Different forms of media are going to begin to interact on the screen experience, and consumers are going to hold on tight.
One reason why this is going to happen sooner rather than later is that it's so darned easy to publish beautiful content, even for non-professionals. That means that advanced content marketers will need to step up to compete–even if it starts in the field of aesthetics.
4. Project management and content marketing will finally formalize
Are you an agile content marketer? A lean content marketer? Do you use online kanban tools to organize your editorial calendar?
I write about project management in my day job, and one trend that I've seen is the evolution of formal project management techniques working their way into the editorial room.
Now, I'm not saying that this B2B content marketing trend is necessarily unique to 2017–I'll admit, I started to see more "agile" content marketing in 2015 and "lean" content marketing became more popular in 2016. For many of you, you're likely already using these techniques and just didn't know what they were called.
Yet, there's still a lot more that content marketing can learn from project management. How can you apply sprints to writers? What processes can be implemented to improve communication between editors and writers? Which writers have the highest productivity? How can you measure quality?
For all of these questions, project management and project management software have answers. In fact, so much so that we might see an equivalent PMP x content marketing certification show up, which brings me to my next B2B content marketing trend for 2017…
5. B2B content marketing certifications and formal courses will reach a higher standard of quality
Most online content marketing courses are garbage. And there aren't a ton of B2B content marketing courses, and those that are are garbage too. Really. You can learn everything they have to teach you by spending time on intro-to-content-marketing blogs for free.
Yet with that said, businesses are seeing real value in content marketing. In fact, it's pretty tough to run an online business competitively without some kind of buyer-focused content.
And business schools are responding. For example, check out these courses: Kellogg School of Management: Understanding the Media and Content and Harvard Business School: Digital Marketing Strategy. You better believe that if top schools are offering specializations into digital marketing and offering courses specific to content marketing, we're going to see a lot more advanced specialization courses and certifications coming through.
Some specifics? I expect there to be an intersection between the PMP and content marketing, big data and content marketing, business intelligence and content marketing, and so on. These predicts aren't for your run-of-the-mill "what's a keyword" course.
I'm talking about courses and certifications that you're glad to have invested in.
More Emerging B2B Content Marketing Trends for 2017?
Let me know in the comments and don't forget to subscribe.


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Exceptional products, outstanding service, guaranteed value. That's our pledge to you and your loved ones. We value the opportunity to ensure your family's safety in the face of tragedy.
Our Mission
It's not easy preparing for the unexpected. That's why the agents at Beacon Financial can help you and your family prepare for the future. No matter what stage of life or situation you face, we offer a variety of life insurance products to offer peace of mind and sound coverage for your family. Our experienced, trusted agents offer an abundance of knowledge and array of options through our vast network of top providers including Mutual of Omaha, American Amicable and United Home Life, to name a few.


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So.. I am going to keep this short and sweet (hard for me as I love to chat!) but this blog really is for you to get to me know a little better, so I am going to be sharing 7 things you may not know about me. Some may come as a surprise.
I think social media is a brilliant tool when used in the right way, so long as we don't obsess and compare as that will cause a silly amount of unhappiness, lack of confidence and generally a less positive outlook on life. I also believe on keeping it real and raw. If you're having a bad day its ok - I mean there is balance in everythingbut also shows you are human y'know.
I am a very upbeat and naturally positive person, you will rarely see me let the hardships of life get to me, I want to live to the fullest everyday. I will always find a positive in every situation and believe every thing happens for a reason. But to keep me, me and real I am trying to show you some of my struggles from daily life to my CF it the hope you can relate in your own little way, we are all in this together. I simply want to inspire, motivate and show you can defy anything you're going through.
Recently, I shared one of my favourite quotes which I turn to when I feel like I have the weight of the world on me as we all have those days.
What I've learnt from life is that for every inch of sadness lies a foot of happiness ahead. I've learnt that the simplest of times bring the grandest pleasures and the hardest goodbyes often lead to the best hellos. I've learnt the crazy chances guide us to unexpected discoveries and tough times unveil sincerity of people. I've learnt that you have to hold onto your smile everyday and free yourself from that frown.
Okay, on to the those 7 things, are you readdddy:
- I was born 10 weeks premature, my birthday is 27 July, I was supposed to be born in October! Clearly eager for life.. I was a little scrap weighting 3lb12oz.
- This may be a shock horror (since my Instagram would definitely say differently) I never used to like eggs… seriously, Mumma Holmes would verify which is why she thinks its funny I am obsessed with them now.
- Before hitting the gym I used to be passionate about sprinting, competing to a high level 100m, 200m & 400m. Until I sadly sprained my ankle badly and so I couldn't run as fast, I was gutted. I still trained though (of course racing the men… to their delight I could beat some of them!) - I mean challenge me and I will push myself but the girls out there are amazing! I miss those days. I am seriously competitive, especially if you get me in the right zone!
- I have to eat a minimum of 3000 kcals a day to maintain my weight. Thats a hell of a lot especially if you are wanting to try and focus on nutrients. (dont get me wrong, I love PNB and Nutella, ice cream, the lot as you know) but due to my poor digestion and not producing digestive enzymes because of my CF (I have to supplement these) I try and eat well or the pain / bloating I suffer is unreal… I even had my appendix out by mistake because it was a misdiagnosed pain (thats a whole new story) If i want to put on weight or lean muscle, well, thats a hell of a lot of eating.
- I have a bucket list of things I want to see, achieve, make, you name it it'll been there of over 250 things - I am slowly working my way through them. Anyone wants to join the journey let me know. My biggest achievement from it is summiting Mount Kilimanjaro October 2015. It was the hardest thing of my life, but, by far the most life changing and incredible. Seriously rewarding. It was also very liberating being cut off from the world (in the nicest possible way) for a week.
- I am a massive adrenaline Junkie! Let me jump out of a plane, gallop or jump a horse at speed, drive a super car, go white water rafting, wake boarding, snow boarding any day.. its these things that give me the bigggg buzz, make me feel alive, the exciting fear you get in your belly. I love it. Most people think I mad, I am, I would rather be insane than boring… I mean I realise they might not be the everyday thing but I will do them as much as I can and even better if I can travel with them too!
- I am actually a qualified legal secretary.. believe it or not. However, it wasn't for me and I love being in the fitness industry. I am not the sort of person who can be sat behind a desk. I love my busy little crazy life running about (literally). Also, that type of lifestyle caused me to be unwell so I wanted to change my life for the better and long term.
So heres a few little facts you may know, if not, you've learnt some new things about me. I am happy to be open and share away so if you have any burning questions drop me a line.


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Building housing is a long, slow affair. It's even slower when developers are building housing for homeless people. Just cobbling together financing from myriad sources can take up to two years, and then there's the permitting, the political haggling, the inevitable negotiations with neighbors. So it's encouraging to see two different attempts to speed up this lumbering process.
The U.S. Department of Veterans Affairs, which has created an ambitious plan for revamping its West L.A. campus and building or renovating 1,200 units of housing for homeless vets, announced that it has hired a principal developer to oversee the rollout. A group of three development firms has formed a company to take charge of the project, work with the community and oversee the other developers who will be hired to build the housing. The principal developer's job is to set a brisk pace and keep the project moving — although in this case, a brisk pace may be wishful thinking. This is a huge task; the VA is essentially building a new town on its grounds. But the principal developer must, at the very least, keep the project from derailing.
Click here to read the full article.


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Today's post is inspired by an "off day" I had last week. Quick backstory: My grandma was one of the greatest sources of unconditional love in my life, and she passed away last year. Although I've done a lot of processing since that time, I still experience waves of sadness, and I found myself overcome with all kinds of emotion last week on her birthday.
It started the second I woke up, when I reached over to turn my phone alarm off, and the first thing I saw was my digital calendar reminder that it was her birthday. My first thought was that I'd forgotten to send a card, and that at the very least I needed to call her! And then my heart sank as I remembered she's no longer with us.
Throughout the morning I experienced a mix of missing her and loving her, sadness and gratitude, and I fluctuated between the two. I consciously sent her soul, wherever it is at this time, as much light and love as possible. But, as you can probably sense, I just felt particularly fragile that day.
It also happened to be the very same day where I'd be meeting 20 new friends at a networking event. We were kicking off the San Diego chapter of a special group I'd applied for called Happsters Squad that's all about bringing positive, like-minded women together to support and uplift one another. I'd signed up for at least a year with this new group of women, and I was so excited to meet all of them. I know how powerful community is and seeing the same people each month provides such a cool container for relationships to develop.
I wanted to make a solid first impression, but the day of the event I just felt...off. While I'm all about being authentic and vulnerable, I also didn't want to unload on or completely break down in front of this new set of people. I wanted to show up as my best self, and channel at least some of my usual, positive energy.
In order to do that, I knew I needed to shift my energy ahead of time. So I utilized the best tools I've got, and I did it! I turned things around by the time the event started that evening.
When I sat down to write today's post, I was reflecting on my experience last week and thought, "I can't be the only one who's ever had an off day and wanted to shift their energy! I'm sure other people experience this too. So why not help them?"
So here we are! I put this list together to help you if/when you ever find yourself feeling funky/emotional before a date, important interview, birthday party, group outing, or just a night in. Because even if other people aren't involved, you don't have to sit in the stickiness if you don't want to.
Ready to feel better? Here are some ways you can get started:
1) Let your emotion up and out. Suppressing it will only make it go away temporarily, and if you truly want to feel lighter, the best way to do so is to actually release the emotion. Find a private space where you can process, and invite whatever feeling is there to come forward. A great way to do so is to play music that makes you emotional anyways (that will always be "Hallelujah" for me...ever since that devastating O.C. episode where a main character was killed off. Those who watched the show -- you know which scene I'm talking about!). Anyways, I can barely handle that song even when I'm feeling great. So when I'm already feeling raw, it makes me tear up almost instantly.
2) Write your feelings out on paper. "Freeform writing" is one of my favorite tools for processing. All you need is a pen, paper, preferably a candle, and a space to process uninterrupted for at least 20 minutes. The process itself involves writing in a stream-of-consciousness manner where you don't filter/edit/even read as you go but rather let it flow on paper. It doesn't even need to be legible, because you're not going to reread it (in fact, I suggest not re-reading it). This is a true emotional purge, and once you're done, you definitely want to discard your paper and get it out of the house. Envision all of your negative feelings leaving with that piece of paper.
3) Share with someone you trust. Sometimes you feel like processing solo, but somethings you need a hug and heartfelt face-to-face support with a loved one. If you feel open to sharing, I suggest doing so with someone who you know can hold space for you and listen without judgment. Feel free to clarify the type of support you're seeking, too. For instance, you might tell a friend that you really just need to express yourself and feel heard vs. receive advice or solutions.
4) Play music that makes you happy. Clearly, I love music! It speaks to me on an emotional level, and if it does for you too, then I highly suggest this step. I personally have (and consistency add to) a "feel good" playlist that's filled with songs that I can't help but enjoy. Pick songs that, even amidst the most stubborn of moments, make you feel even a little better.
5) Take a warm bath/shower and imagine it all rinsing away. I especially love this after doing some emotional processing. Sometimes I'll even suggest it to clients after a particularly deep session together where we've cleared and lifted so much material. Picture any residue of emotions that are no longer serving you in this moment swirling down the drain. Bonus points if you indulge yourself with a bubble bath, oils, or bath product that feels luxurious. Which brings me to my next point...
6) Treat yourself to an easy ritual or pampering experience. For example, I have a face oil that I keep in the shower, and when I'm feeling like I could use a 'lil extra R&R I'll take a few minutes to massage it into my skin, focusing on releasing tension in my temples or jaw. Then, I'll take a warm wash cloth and place it on my face as I imagine the oil sinking in and hydrating my skin before gently exfoliating and rinsing my face off. It's a quick, simple way to make myself feel cared for and treated.
7) Step outside. Spend a few minutes in the sun, breathing in fresh air and coming into the present moment. Try and notice the little details and signs of life all around you -- simple things about your environment that force you into the here and now. It's hard to be so in your head/trapped in your own inner experience when you stop to notice the clouds, the way the light is hitting the trees, the scent in the air, the temperature, a plane up above, a gecko scurrying into a bush, or how the flowers next door are coming into bloom. You get the idea :)
8) Watch a funny YouTube video/movie clip. This can work wonders! Look up whatever kind of content makes you laugh. I personally love random quirky characters on informercials. A few of my personal faves are this camera informercial mixup, this extremely enthusiastic rainbow sponge salesperson, and this cat massage expert.
9) Ask for (and receive) help. Maybe you have a friend who possesses a magical ability to make you laugh, and you know that even a quick phone call with them would brighten your day. Or perhaps you need some time to yourself this afternoon, and it would mean the world to you if your husband would take the kids to the park. Whatever comes to mind, go ahead and make a genuine request without attachment to the outcome. This is just about making your needs known, and seeing if the other person is available. They may or may not be, but if they are, be sure to graciously receive their support. Let it sink in and take full advantage of it. Last week, my fiancé drove me to and from the networking event I mentioned earlier, because we both knew that a car ride spent cracking each other up would fill me with a lightness and allow me to bring my best energy forward when meeting this new set of people. In the past, I might have shrugged off this help because I knew he was going out of his way for me. But I've learned that when we accept the support of others, it's a gift to them too...because it feels good to help someone out, especially someone you love.
10) Focus on one positive potential outcome. Choose at least one aspect from a best-case scenario that generates some positive emotions. Maybe it's getting the job, making a romantic connection, or getting into a headspace where some new creative ideas can flow your way. Whatever it is, go with it -- put energy into it, and allow the feeling to pull you forward. For me, I knew this new group was made up of dynamic, fun, upbeat women who were equally excited to meet people. Therefore, I knew that the odds of making a new friend connection were solid. Focusing on that allowed me to channel more feelings of excitement.
And, if nothing seems to be working...it's also okay to bow out, take it easy, get a good night's sleep, and start anew tomorrow. Everything always seems to feel at least a little better in the morning.
No matter what, you have full permission to feel however you feel. You're a complex, multifaceted, emotionally dynamic human being. Which, if you think of it, is a pretty amazing thing.
My hope is that this guide provides you with some helpful tools to feel better as soon as possible. If you try any of the above, keep me posted! I'd love to celebrate your wins with you!
To more "on" days than "off" days,
P.S. If you find yourself having a bunch of "off" days in a row, it might be time to implement some bigger life changes. If that's the case, feel free to message me. I'm happy to support you in figuring out how we can get you feeling more like yourself again.


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July 11, 2003
By Mary Rohrer
Check out more photos from this outing in our Photo Gallery!
We had a great July outing in Junction at the Morgan Shady Campground along the South Llano River. TWFF members started to arrive mid-day Friday in all sorts of camping facilities….large RV's, fifth wheels, casitas, popups and tents. The campground is beautiful, right on the banks of the South Llano River under large pecan trees.
Lavene Hardin was an excellent campground host, welcoming all of the TWFF fisherwomen to our various campsites. We also had a handful of Austin TOWN members join us to kayak in the morning. All in all, we had about 40 women and invited guests for the weekend.
Saturday morning we loaded our kayaks and supplies onto trailers and into the backs of pickups and other vehicles for a ride upriver to the entrance of the South Llano River State Park. We launched the kayaks just below the low-water crossing to begin our six-mile float to the campground. Nancy Burns, of Alamo City Rivermen fame, joined us to keep our minds on the river, not just fishing. The float had a few challenging spots where leading your kayak and walking through some swift water was definitely the safer way to go. The South Llano River is full of perch and bass. Generally the fish were of good size as compared to the same species of fish on the Llano River near Homer Martin's place. Wooly buggers, poppers (like Miss Prissy, of course), and jigheads were successful flies for the river. We had a great lunch spot on the riverbank under a large pecan tree then proceeded at our own pace back to the campground. Julie Sieh caught her first fish, a good-sized perch on her fly rod using a popper that Ronnie Ray gave her.
Late Saturday afternoon, we had a quick board meeting, and then proceeded to a banquet dinner at Isaack's Restaurant. Isaack's is known throughout this part of Texas for its famous chicken fried steak. It lived up to it's billing. No one went home hungry after our meal. The banquet was an enjoyable way to finish up the day, sharing stories with our friends about the float. At the business meeting, we discussed and voted on several things, the most important one being the beginning of a Friday night Mullet Mixer at each outing to make it easier for outing participants to meet and make fishing plans. The first one will be held at the Redfish Rodeo outing in Port O'Connor. Back at the campground, we watched a very large full moon rise above the cliffs on the far side of the river. Quite a sight at such a pleasant place. Sunday came too soon, with breaking down camp and taking off for home. The Morgan Shady Park campground was a great place for TWFF to spend a hot weekend in July. It was an excellent place to stay. Several people mentioned they would coming back and bringing their families. The small town was very quaint and the fishing was good.


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Argus Interactive Agency
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Also, synchronizing the content you display with the keyword expectations of an individual searcher can play a huge role in click-through rates. Landing on the right page with relevant and compelling messaging with simple, clear action steps increases the potential customers trust that he or she is at the right place and can easily take action.
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Please contact us to discover how Argus Search Marketing can improve business performance and make the search engines talk about you over the other guys.
>> NEXT: What is Link Popularity?


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California's Drought Has Reached a Grave New Milestone
At least 182 of the 1400 households in the town have run out of well water, prompting the county to provide 12 gallons of water for each resident that is facing water scarcity. With the help of the Red Cross, the bottled water was supplied at the cost of 30,000 dollars, and is expected to last 3 weeks. For some residents, the shortage is just too much.
East Porterville resident Angelica Gallegos fought back tears as she described being without water for four months in the home she shares with her husband, three children and two other adults.If you can believe it, the number of properties with dry wells may in fact be higher. Some residents are afraid to report these issues for fear of being evicted by their landlords, or possibly having their kids taken away by CPS.
"It's hard," she told The Bee. "I can't shower the children like I used to."
Farmworker Oliva Sanchez said she still gets a trickle from her tap, but dirt started coming out with the water about a week ago.
"I try to use the least possible. I'll move if I have to," she said.
As insane as that sounds, it may be the least asinine part of this whole situation. Perhaps it's fitting that these folks are receiving their aid in the form of bottled water, because nearly every water bottle company is situated in some of the most drought stricken places in California. Apparently, California is one of the few states that doesn't protect groundwater usage, so corporations are free to bottle it up from the local springs or the municipal water supply.
It's total madness when you really think about it. These companies are still bottling up precious water so it can be sold across the country. And there isn't even anything special about it, since nearly half of all bottled water is nothing more than tap water. In parts of the country where people do have plenty of water, they can buy California's dwindling supplies at a significantly higher price than their tap water, even though it is essentially the same thing. As reported by Mother Jones:
Despite the fact that almost all US tap water is better regulated and monitored than bottled, and despite the hefty environmental footprint of the bottled water industry, perhaps the biggest reason that bottling companies are using water in drought zones is simply because we're still providing a demand for it: In 2012 in the United States alone, the industry produced about 10 billion gallons of bottled water, with sales revenues at $12 billion.Perhaps running out of drinking water isn't the only major milestone of this drought. We have now reached the same situation that countries like India have been dealing with for decades, where the Coca Cola Corporation can build a bottling plant that soaks up all the groundwater from the region, leaving the locals high and dry. The drought is showing Californians what it's like to live in a third world country for the very first time.
Delivered By The Daily Sheeple


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"Hi my name is Steve and I had some high blood pressure issues. My health was generally poor until I ran into Dr.Joe with the PowerPack3. He turned me onto this stuff and now I feel great!
Not only do I feel great, but my blood pressures under control.
It's so easy to take, I take them and put them in my pocket. during the course of my day when I have my meal I take them out of the pack slip them right into my mouth and they're easy to digest. Real fast and easy and keeps me on the run.
My recommendation to you guys is the PowerPack3. Have a great day!"Steve Lemanna, Age 53
Computer Repair Business Owner
Saint George, New York
Read Next


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Follow the Sun Festival announces Adelaide location
Alana Trezise
With the recent announcement of Falls Festival, and Soundwave lineups, there has been a nation-wide excitement brewing for the Summer music festival season to begin. Luckily enough, Adelaideans won't have to wait too much longer - because this year our festival season is starting in Spring thanks to Follow the Sun Festival.
The one day blues and roots music festival aims to celebrate Aussie artists and boast a boutique music festival experience with a comfortable, relaxed and alternative vibe. Founder of the event David Elmes, also aims to support local in the way of food and beverages, which will include delicious food vendors, local wineries and a range of boutique beers. He says, "Some outstanding Aussie music talent and a few drinks with your mates. What could be better, It will almost be like a party in your own backyard" ...and we couldn't agree more!
Some of the festival line-up includes Something For Kate's Paul Dempsey, BONJAH, and home grown talents Ciaram Granger and Alice Haddy.
Held in the iconic beachside suburb of Glenelg, the festival will be happening at Wigley reserve on October 5th, from 12pm until 10pm. Get your tickets at oztix and suss out the Follow the Sun website here.


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On Vegan Barbecues, Celebrations and Vegan Fondue!
Listen on the go!
This week was a fun filled one for sure. We got to do a lot of celebrating and spend time in nature and with friends. We went to our favorite vegan restaurant in Madrid, Rayen Vegano, and I made the most scrumptious vegan cheese fondue and stuffed phyllo triangles which you'll see below.
Fondue was always one of those things I thought I was swearing off when I went vegan, but rest assured that this is not the case at all! It's so easy to make and extremely decadent, creamy and delicious. I'm still tweaking it a bit, but as soon as it's perfect we'll be filming a little video for you!
It's Monday today, which means that although we had to share the exciting news about the launch of our 3 step guide to healthy eating, it's all about the vegan grub today and we definitely ate some amazing food this past week and have some great ideas to help inspire your meals. Let's get to it!
Our favorite breakfasts
I once heard an interview with the amazing creator of the Jivamukti school of yoga and author Sharon Gannon in which she was asked what her favorite thing to eat was, to which she replied: toast! I laughed out loud in my car because I could completely relate to her love of toasted bread with something on top. This one had some almond butter, banana slices, mango and some chia seeds plus a tiny drizzle of agave on top.
You've heard me mention that perfect combination of oats, pineapple and coconut before, and this was what I call our delicious piña colada porridge. If you're subscribed to our newsletter this was our bonus recipe a couple of months back. It's tropical, so refreshing and good for you.
Our favorite lunches
If you thought I'm always making elaborate vegan dishes in my kitchen you're so wrong! I LOVE simple and easy cooking as much as the next person. Recently I've been obsessed with making a simple sauté of peppers, onions, mushrooms and quinoa with a little tamari soy sauce, lemon juice and pepper. This time I served it with some hummus on top and a side salad of mixed greens with a little pumpkin seed oil and balsamic. Pumpkin seed oil is amazing for your hair and skin because of its high zinc content, as well as for men's hormonal and prostate health.
We had an amazing vegan barbecue in our terrace yesterday. The dogs love hanging out outside, we play some tunes and the best thing ever: Carlos does the cooking! The only thing I do is make my famous baked tofu (if you're a member of My Brownble you can find this recipe in your staples section) and the guacamole. We had grilled corn on the cob, crispy baked tofu with barbecue sauce, grilled smoky onions, tamari marinated shiitakes, grilled asparagus and peppers. It was perfect!
Our favorite dinners
On Friday night we went out for amazing vegan grub at Rayen Vegano. Carlos had their trio of burgers on beet bread.
I had their seitan steak with grilled polenta, baked apples and mushroom gravy. So hearty and "stick to your ribs" good. We also had their lemon blackberry cheesecake for dessert.
On Saturday night (I'm just realizing we had a jam packed weekend!), our friends Any and David came over to our house for dinner. I made these stuffed filo triangles with a portobello, onion and cream cheese filling that were unbelievably crispy. These were served with a dipping sauce on the side. I highly encourage you to start experimenting with filo dough. It's so easy to handle and use and it can completely elevate any dish you make to new heights.
The star of the show however was this creamy vegan cheese fondue which I served with some rustic bread, roasted potatoes with truffle oil and vegan chorizo for dipping. I can't even tell you how good it was.
This week's "oh so sweet" treat
After all that naughty goodness we still had dessert, and this one was a total request from our guests who are obsessed with cinnamon rolls! You can watch the video and find the recipe for these here.
Don't forget to share this post with anyone who is wondering about what goodies you can eat as a vegan and I'll see you in our next post!
What delicious plant based meals did you have this week? Leave them in the comments below!


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This Aspen ski resort cam in Colorado is overloking the well know mountain resort and the ski slopes at the skiing area in Aspen
Aspen began life as a silver mining town and has now become one of the world's most famous ski resorts with its lively feel and stunning views of Aspen Mountain. Aspen has attracted the rich, the famous and, of course, many ski enthusiasts to live and stay. Well worth a visit.
This Aspen ski resort webcam in Colorado is provided by Liveaspencam. For more Aspen skiing info visit this website HERE


text: All our vehicle deliveries, Toyota events, functions and launches at the dealership are captured in the albums below. If you have dealt with our dealership and feel you would like to appear in any of our galleries, simply send us your photo and a small note about your dealings with us. Here at Rola Bredasdorp we are proud of our customers and feel the excitement when we are able to put them in the cars of their dreams, and our gallery is our way of sharing this excitement with everyone.


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'Who sees the wren,
sees god.' –it's true.
But first you hear
sweet sounds
of stream, at play,
with stones and sand,
the laughter of the god.
Only then you see
the tiny form,
the bird, the god.
Trill shakes
the angled tail,
song eternal,
leaves shudder to alert
the hawk,
another god, another sound.
Poetry: Sarah Fuhro Photo: Robert Fuhro


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Think and Grow Rich coffee mug, journal, shirt, coin, smartphone cover, and book bag. For details, click HERE
Wisdom From The Hill is a series of quotes from Napoleon Hill to inspire and encourage you to discover and pursue your life purpose and goals.
Would weekly one-on-one video coaching by a Napoleon Hill Foundation Certified Instructor help you stay accountable to, and achieve, your life's purpose and goals faster than what you are currently doing? For details, and to schedule a free 1 hour video meeting, click HERE
Order your smartphone case HERE


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Property Details
691 Centre Road BENTLEIGH EAST, VIC 3165Leased
Retail - BENTLEIGH EAST VIC
Gross Waddell are pleased to present this food retail premises located in busy Bentleigh East.
The premises is located amongst a number of popular local Asian eateries and Pizza Restaurants, as well as service retailers such as Allied Health Providers and Personal Beauty offerings.
The premises would suit a food retailer, that requires a head-start in owning an eatery. Alternatively, another retail use such as an office would also enjoy significant exposure on this corner location.
– Building Size: 100sqm (approx.)
– Grease Trap and Canopy
– Cool room
– Prime Centre Road Shop Front
– Suits a variety of uses (STCA)
Property Features
- Retail
- Floor Area is 100.00 m²
- 2 Car Spaces
Commercial Features
Commercial 1


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Uber-indie director Kelly Reichardt's Old Joy looks at the camaraderie between two best-buds on their isolated weekend camping trip. Mark (Daniel London) and Kurt (Will Oldham, aka Americana troubadour Bonnie Prince Billy), are atypical of many thirtysomething men in American film, in that they are incapable of illustrating their emotions. With so much tension all-too-comfortably bubbling away underneath, and with very little else on display in regards to drama or narrative, Old Joy is a frustrating watch; with very little for even the most Bonniest of lasses and Billy goats.
THE GOOD: A) Yo La Tengo soundtrack, when we get a chance to hear it.
B) Will Oldham is a doobie brother.
THE BAD: Lack of authorship and focus.
THE UGLY: How this seems like a pretty big mis-swing, on all accounts.


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