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I set out on this trip with a pretty lofty goal, to catch a steelhead trout by fly rod in Washington, Oregon and California, all while pedaling down the cost. While finishing the ride was also part of that goal, it was always secondary to the fish. I guess that is indicative to life in general. My riding buddies are constantly giving me grief when I go fishing rather than hitting the trails.
Washington provided ample opportunities on the Peninsula, but it wasn't to be. Eight days on the five rivers without even a tug (except for one beauty of a bull trout). Oregon was even less productive as the rains picked back up and blew out nearly every river I pedaled past. I spent four days on three rivers, finding a couple nice sea run cutthroat trout, but no steelhead. By the time I arrived in northern California, I had almost given up hope. Just about everything I wanted to fish was brown and high, unfishable.
Continuing south, there were only a handful of steelhead rivers in front of me. I consulted a friend, and he confirmed that conditions were "perfect!" on a river that I would soon pedal past. I called the local bait shop, and a gravelly voiced woman proclaimed the river was "as good as gold!" Things were starting to look up.
There was not a soul to be seen despite the fact it was of the best looking fly fishing runs of the trip. I set up camp on the banks of the river, wadered up and fished all afternoon, meticulously covering the water two steps at a time. Despite high hopes, and a feeling that this was my best chance, nothing happened.
I decided to give the same run a second chance, but started higher up this time. Studying this new water, I was sure it was going to happen here or not at all. I made four or five casts, pulling out more line after each cast. On the sixth cast, as the line was tightly swinging across the current, I felt the sharp tug...tug.tug of a fish. Having fished so long without even a bite, it would have been easy to react with too much enthusiasm and set the hook prematurely, pulling the fly out of the fish's mouth. Surprising myself with the calm of a seasoned steelheader, I let the fish pull a foot of line out of my hand, until the fly was solidly seated in the side of the fish's mouth. Only then did I set the hook, and realize I had the first steelhead of the trip on my line. Within a few minutes, I was holding the hardest earned, most rewarding fish of my life. It wasn't the biggest I've caught, nor did it put up a particularly memorable fight. It was a native female steelhead, chrome bright, not even a mile from the ocean. It showed the scars of a challenging life, but was beating the odds. Only 5% of her sisters and brothers will likely survive from egg to mature adult and return to their natal stream.
With her tail in my hand, I gently removed the barbless hook and cradled her body under the water. After snapping a photo, she kicked her tail strongly and continued on the journey upstream where the next generation of steelhead will be born.
When you prepare for something for so long, it's hard to know how you'll feel when the thing actually happens. In this case it was as good as I've dreamed. I couldn't believe what had just happened. I simply sat down on the gravel bar, smiled and basked in the sun and the feeling of success. I had all but given up hope on finding steelhead.


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My second beta was at 9am yesterday. As I sat down in the chair and rolled back my sleeve, I fought back the tears. So much was riding on these results. "How are you doing?" the young nurse asked.
"I'm terrified," I replied.
"Of the needle or the results?"
"The results."
"You just have to stay positive," she declared.
I wanted to scream. To ask her if she had any idea what this really feels like. Ask her if she'd even bothered to read my chart and realize this was my one and only chance at a successful pregnancy. That all nine of my other embryos had arrested development due to what the doctor thought were issues with our sperm. Of course, I didn't say any of those things. I just sat there as I watched her poke into my vein; already bruised and sore from the test two days prior.
The nurse told me we'd get a call to report the results sometime after noon. I muttered my thank you's, and stumbled out of the office.
We anxiously awaited the results all day long. I wanted to get the news with Chris, and left work a little early so we could be together when we got the call. By 5:30pm we still hadn't heard anything. Chris was antsy as hell, and I kept telling him, "I know they'll call before they leave at six. If not, we'll do a home pregnancy test."
He finally broke down and called our RE on his cell phone. The one "for emergencies only." Heck, it felt pretty urgent at 5:40pm on a Friday before a three day holiday weekend. Our doctor said perhaps we wouldn't receive the results until Tuesday. As luck would have it, our nurse began calling us while Chris was wrapping up the conversation with our doc.
Chris missed her call, so we dialed her back on speakerphone. She sounded cheerful. "Oh, hi Chris! I was just leaving you a message on the other line. We got your results back, and they are negative." I felt numb. "Please tell Heather to stop taking her medication. If you'd like to schedule a follow-up meeting to go over your cycle with the doctor, that can be done either in person or over the phone. Just call us next week to schedule when you're ready."
Before hanging up the phone, Chris managed to ask her, "What exactly were Heather's beta numbers?"
"Less than two," she informed us, "we consider anything over five to be pregnant."
We sat in silence for a few minutes. I slowly got up, and began gathering all my medicine from around the house. The Crinone, the bottles of Estradiol I had in my purses, and by my bed. I put them all in a bag, and shoved them into our guest room closet. I went to the kitchen, and gingerly pulled the magnets off the fridge that surrounded the little pictures of our precious embryo and my uterus-post-transfer. I carefully found an envelope and filed it away in the filing cabinet.
I went back to the bedroom and began to sob. Chris was crying, too. We sat on the floor and held each other for what felt like hours. We managed to feed ourselves dinner and put on a movie. All events throughout the evening were punctuated with tears by one or both of us. It felt, and still feels, surreal.
To add insult to injury, we received a bill from the pre-IVF genetic counseling. Nearly $8,000. We had no idea a bill of that magnitude was still coming. It felt like a sick joke.
Today, both of us are processing. We could do IVF again as soon as July. We both have so many questions. Do we want to use the same clinic again? Will we have different results next time? When will we know it's time to give up? Should we consider adoption?
It feels like we have a lot of healing ahead of us. I'm really grateful to have such a strong teammate by my side through this process. We'll get through it together. For now, we just need to grieve.

subset: commoncrawl


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January 18-27, 2019
Grow Op is a four-day festival that will transform the Gladstone Hotel with 30+ immersive installations that celebrate innovative ideas and conceptual responses to urbanism, environmental sustainability, landscape design, and contemporary art. Think Allan Gardens meets Come Up to My Room!
What lies beyond once the floodwaters recede? What emerges once the smoke clears? As cataclysmic climate events multiply in tandem with our species' continuously expanding footprint, we are re-conceiving our relationships with the organic and inorganic world around us in unprecedented ways! Grow Op 2018 employs the tools of art, craft, and design to question our conceptions of urban and wild curated by Christine Leu and Alan Webb of LeuWebb Projects with Lukus Toane.
Click here for tickets!
Photography: Gabby Frank
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Thanksgiving Day is around the corner. This day comes a day to Black Friday a day which people go mad shopping for the best tech and toys on offer. Everyone scramble for an opportunity to walk to the store and get out with on-trend electronic or tech products or even buy a toy for their toddlers as part of celebrating the Thanksgiving holiday.
But is it true that the Black Friday deals are the best offers that every shopper should die for? Is Black Friday a good time to prepare for the December holidays? Here are the three misconceptions about Black Friday deals:
Retailers with black Friday sales advertise them beforehand
One of the misconceptions held by shoppers is that all deals for the Black Friday will appear on ads before the dawn of this day. As such, if a retailer does not put an advert on the same, they are not taking part in this massive shopping event.
What you do not know is that all stores have different ways of reaching their customers without having to advertise their offers through the mainstream media. Hence, even if you do not see a black Friday ad for your favorite brand, it is not an indication that they will not be giving out a discount. In fact, this might be a strategy to beat their competitors by offering higher discounts on that day.
Black Friday deals are Amazing
Another misconception you will hear from shoppers is that missing out the deals on offer on Black Friday; it is the worst mistake you can ever make in your entire year. Also, shoppers think that you will always get the best tech and other items at an affordable price. This might be untrue. Some stores may just be disposing of excess products that may not meet your specifications. However, you cannot miss a fantastic offer all the same.
Superbrands are reluctant to take part in Black Friday deals
Most shoppers hold a view that Black Friday is a day for upcoming and small brands to maximize their profits through offering wooing discounts. They think that superbrands do not need to go for these deals as they already have sold enough items and have firm offers. In practical, the brands may not directly be offering the Black Friday deals. Instead, they do it through third-party stores such as Walmart. Hence, you can find your high-end brands on offer from the mainstream stores.
Now you know what is not true about Black Friday deals.
New post (2015 Black Friday / Cyber Monday Equipment Sales…) has been published on Black Friday Deals – https://t.co/9bb9TPNkmw pic.twitter.com/oxoiMt6JUW
— Black Friday Deals (@Thefirdaydeals) 12 de octubre de 2017
7 Helpful Black Friday Sales and Marketing Tips for Small Businesses


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You see a bucket filled with toys...
I see my creativity being stifled...
Hey! Don't judge until you try it.
You see a bucket filled with toys...
I see my creativity being stifled...
Hey! Don't judge until you try it.
Nice collection of toys there! I have my favorites too...
My mom/person says...AWWW what a cutie!!!
I thought I was looking in the mirror! hee hee
Paws UP!
Hey, it worked for Mary Poppins ...
I completely understand your problem, Calvert - my human stifles my creativity all the time. It takes me a whole week to get the house just right, and then she comes along and ruins it!
Humans just don't understand us artistic types.
Puppy kisses
So very, very wise oh great Calvert.
They just don't understand us. Sigh.
Wags and kisses, Dinah and Bridget xx
humm I would like to be there to play with you my sweet friend, I specially love that cute green frog, maybe if I could give him a CATKISS he would become a Prince! ;)
Beautiful pictures!You look so comfortable in that spot!Enjoy it!
purrs and love
your friend
Luna :)
Ugh, as soon as I get things just right, my people come along and "tidy" them up. If I wanted them like that I would have done it in the first place.
Stick to your guns, Calvert! People can evenutally be trained.
Hi Calvert - we feel your pain. Luckily, we live with some pretty lazy humans (he he he!) so our creativity only seems to get stifled whenever guests are due - ha! By the way - we ADORE that last photo of you, female human nearly pierced our eardrums with her squeals! Schnauzer snuggles - JD and Max.
Thunder Dunder so understands your problem, Calvert. He takes great pleasure in scattering his toys from one end of the house to the other but some humans here are always putting them back in the toy box - what are toys for anyway???
Woos, the OP Pack
Do you know that you're so photogenic, boy the last pic will take many girls' breaths away.
And Savvy, Princess Savannah, you took Riley, my friend's breath away!
Love y'all
You have so many toys,
i wish I could play with you :)
Lovely shots all .....
HUGS love
Kareltje =^.^=


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Solar Thermal Energy
The solar thermal energy consists of the use of the energy coming from the Sun to transfer it to a medium that carries heat, generally water or air.
Among the different applications of solar thermal energy there is the possibility of generating electrical energy. The current technology allows heating water with solar radiation to produce steam and then obtain electrical energy.
Although the principle of operation is very similar there are two main applications of solar thermal energy:
- Use of solar thermal energy in homes and small installations
- Large thermal solar power plants. In these plants the heat is concentrated in a point to generate steam, with the steam a turbine is driven to generate electric power. Once the heat is generated, the operation of a solar thermal power plant is very similar to that of a thermal power plant or a nuclear power plant. The difference lies in the fact that a thermal power plant the heat to generate the steam comes from the combustion of fossil fuels, normally coal, and in a nuclear power plant, heat is obtained by fissuring the nucleus of uranium atoms.
The collectors of solar thermal energy are responsible for capturing the thermal energy of solar radiation. These solar collectors are classified as low, medium and high temperature collectors depending on the way they work.
- Low temperature collectors . They provide useful heat at temperatures below 65 ° C.
- Medium temperature collectors . They are the devices that concentrate solar radiation to deliver useful heat at a higher temperature, usually between 100 and 300 ° C.
- High temperature collectors . They work at temperatures above 500ºC. They are used for the generation of electrical energy.
Systems that form a solar thermal installation
The basic scheme of a solar thermal installation is the following:
A solar thermal installation consists of several systems:
Solar radiation collection system
The solar radiation collection system consists of solar collectors connected to each other. Its mission is to capture solar energy to transform it into thermal energy, increasing the temperature of fluid circulating through the installation.
There are a lot of systems for capturing solar radiation. The choice of one system or another will depend mainly on whether it is solar thermal installations of low, medium or high temperature.
Among the different solar collection systems we highlight:
- Flat solar collector. It is the most widespread solar collector, you can get temperature increases of 60 ° C at a reduced cost. It is used in low temperature thermal solar plants.
- Solar thermal collectors not glazed. It is common, for example, to heat the water in swimming pools. The temperature increase is low, around 30 ° C. They are more economical than flat solar collectors.
- Vacuum solar collectors. They consist of metal tubes that cover the metallic tube that contains the working fluid, leaving between them a chamber that acts as an insulator. They have a very high yield, but their cost is also high.
- Solar collectors with radiation concentration systems. They are used for installations that require higher temperatures. Parabolic or semi-cylindrical panels are used.
- Solar thermal collectors with tracking systems of the position of the Sun. Its position varies throughout the day to maintain a position perpendicular to the received solar radiation.
Thermal solar energy accumulation system
It consists in storing the heat energy in an accumulation tank for its later use. The hot water obtained through the collection system is conducted to the place where it will be used.
The stored hot water can be used directly, as is the case of heating the water of a pool, in hot water or heating applications the demand.
Because the moment of need for hot water does not always coincide with the moment when there is enough radiation it will be necessary to make the most of the hours of Sun to accumulate the thermal energy in the form of hot water.
The thermal energy storage system consists of one or more hot water tanks. The size of the storage tanks must be proportional to the estimated consumption and must cover the hot water demand of one or two days.
Distribution system of solar thermal energy
Once the solar collectors have heated the heat carrier medium (water or air) increasing its thermal energy, we can transfer this thermal energy to other colder sources.
In this system all the elements destined to the distribution of the medium carrying heat and conditioning to consumption are included: control, pipes and conduits, expansion vessels, pumps, purgers, valves, etc. Also part of this system is the support system based on conventional energies (electric, gas boiler or gas oil), necessary to prevent possible faults derived from the absence of solar radiation and deal with peak demand.
Conventional energy support systems
The solar thermal installations need conventional support systems in anticipation of the lack of solar radiation or consumption exceeding the dimensioning. In most cases, both in installations in single-family homes and in residential buildings, solar installations are designed to provide homes with 60-80% of the hot water demanded, although in areas with high sunshine throughout the year. year, the contribution percentage is usually higher.
These energy support systems can be from various sources. If the installation is connected to the network, it can take advantage of the electricity supply of the electric company itself. In other cases you can use other sources of renewable energy (wind energy or hydroelectric power if conditions permit) or non-renewable energy sources. Non-renewable energy sources can be from fossil fuel derivatives (oil, coal or natural gas), in some installations pellet or biomass boilers are used.
In the months of lowest solar radiation, it does not reach 60% of the energy needs. On the contrary, in the summer months almost 100% of them are reached. Thus, the objective with which solar thermal installations are designed is to cover a minimum of 60% of the annual energy needs depending on the geographical area.
Trying to cover over 60% or 70% per year of solar thermal energy would require placing a very large solar field, which would result in an extremely high cost that would never be amortized. In addition, such a large solar thermal installation would cause in the months of increased solar radiation a production surplus that could not be used and would cause overheating problems throughout the installation.
For this reason the facilities that work best and are profitable before are those that need sanitary hot water for the whole year, heating for winter and have a pool for summer or even all year.
Economic and social aspects of a solar thermal installation in a house
The initial investment of a solar thermal system will be greater compared to a conventional energy supply system. On the other hand, the operating cost during the more than 25 years of life of the solar thermal installation will be irrelevant compared to the purchase of fuel or electric power, repairs, maintenance, etc. associated with the conventional energy system.
The installation of solar thermal energy is economically more economically advantageous, since all the energy that we obtain from the Sun with the solar thermal sensors, will be energy that we will save it from producing (burning fuel in a boiler) or consuming (from the electric network of distribution). A solar thermal installation ends up being profitable throughout the years, since the energy saving that it produces materializes in economic savings, which allows to end up amortizing the cost of the installation. This amortization can vary between 5 and 12 years depending on the size of the installation, the aids obtained in the form of a lost fund, the place where it is installed (more or less solar radiation) and the greater or lesser needs of the user.
In the case of placing these solar thermal installations in new construction or rehabilitation houses, the amortization can be considered instantaneous, since the increase that represents in the total price of the house is very small; the amount paid for that higher cost in a mortgage loan each year is less than the amount in euros that involves the lower cost of gas or diesel.
We highlight the main advantages of a solar thermal system:
- Economic advantages For the same needs, the conventional system will need to consume less fuel (derived from fossil fuels or biomass), which will represent a lower annual expense for the user. In addition, solar energy is independent of conventional fuel and its supply, since it is compatible with any conventional system and independent of the variation in the purchase price of fuel.
- Environmental advantages, since the generation of energy with conventional systems has very significant environmental costs (CO2 emissions , climate change, greenhouse effect, discharges, nuclear waste, acid rain, etc.) in relation to solar systems. On average, one m2 of solar thermal collector is able to prevent the emission into the atmosphere of one ton of CO2 each year .
- Easy maintenance. The useful life of thermal solar installations is greater than 25 years and the maintenance required, although it is necessary to do, is much less important than in the case of conventional systems.
However, the installation of thermal systems presents a drawback: it requires the installation of the same conventional system that would result if the solar collectors were not installed. Sometimes it is problematic to assemble them in existing buildings as a consequence of their lack of foresight at the project level.
- Aplicaciones Domésticas con Energía Solar
- Solar Thermal vs. Photovoltaic
- Solar Process Heat
- ORNL's liquid fluoride proposal
Last review: April 17, 2018


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When I was a baby my parents had me baptized. I of course have no recollection of this event. I do, however have a charming, very '70s photo of our family outside the church on the day of the event. I'm not sure why it didn't occur to me to get baptized as a believer until I was halfway through college. But by that time I had experienced a different kind of baptism.
I was raised in the Nazarene church, which is a holiness church. Now all Christian churches should be holy and should value holiness intrinsically, but there are certain denominations whose core identity is the pursuit of holiness before God, and which were born during a move of God that especially emphasized holiness. Such is the case for the church of the Nazarene, which, along with a handful of other denominations, grew out of the holiness revivals that swept the U.S. in the second half of the 19th century.
Let me define holiness as I understand it. It is closely related to the words consecrate, sanctify, sanctity, and sacred. All of these words contain the idea of something being set apart from ordinary, everyday use for a special purpose: one that relates to God. When I was a teenager, I remember once my father asking our church what "holy" meant, and the answer that occurred to me was "close to God." The question then is, how does one get close to God? The first answer to this is that we can only come to God through Jesus, his son. As we trust in him and his sacrifice for us, he makes us holy, and gives us the right and privilege to come close to God. But the holiness churches also highlight the need for believers to set themselves apart from the world by devoting themselves to godly action and avoiding sinful and corrupting activities and attitudes.
There is a doctrine in the Nazarene church and other holiness churches that comes from the Methodist and Wesleyan tradition, of sanctification. The idea is that as we separate ourselves from the destructive practices and values of the world, God will do a special work in our hearts that truly changes our attitudes and desires. This has been likened at times to the baptism of fire spoken of by John the Baptist, who said, I baptize you with water for repentance, but he who is coming after me is mightier than I, whose sandals I am not worthy to carry. He will baptize you with the Holy Spirit and fire. (Matthew 3:11) It seems that many of the early Nazarenes and others from that movement had dramatic experiences with the presence of God and even fire, as recalled by old hymns like How the Fire Fell. Here is verse three and the chorus from that hymn:
To the world no more my heart is turning since the Lord sanctified me; For on me His Spirit fell with burning when the Lord sanctified me. O I never shall forget how the fire fell, how the fire fell, how the fire fell.O I never shall forget how the fire fell when the Lord sanctified me.
I must have only been ten or eleven years old when I heard this message preached powerfully and clearly at Temple City Church of the Nazarene in southern California. I came up at the end and knelt at the "altar" which was something like a long bench that ran along the front of the platform of the church. Altars in the Jewish tradition were structures of stone or bronze where priests would offer animals as sacrifices to the Lord. There were various types of sacrifices, but one was the burnt offering. Other sacrifices were partly used for food, but as described in the first chapter of Leviticus in the law of Moses, a burnt offering was completely burnt up "with a pleasing aroma to the Lord." In the same way, a person seeking sanctification was instructed to put everything on the altar (figuratively speaking). So every area of my life is to be devoted to his purposes, to be holy. This was the call I responded to, and as I poured out my ten or eleven-year-old heart and accepted this challenge to completely devote myself to the Lord, he changed something inside of me. He received my sacrifice and then he himself set me apart for his purposes. We can only live a godly life, pleasing to him when he has poured out his Spirit and fire upon us, consuming the sacrifice of our lives! This is available for every believer in Jesus, not only those in certain denominations.
I definitely did not live a flawless life from then on, but there was a change in perspective and in my desires—I no longer only lived to please myself, but to know and please the Lord. I believe that I experienced a baptism of fire that burned away my foolish, sinful desires so that I could devote myself to serving the Lord in a new way. I still had a lot to learn about how to live out that commitment, but this experience was a foundation for godly living that I could look to and build on from that time on.


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Throughout the summer we want to take some time to introduce you to all of our vendors! Today's Spotlight is on Anastasia Marino with Gypsy Cart Arts!
Anastasia is a self-taught artist who has been dabbling in different mediums for eight years. Her products are one of a kind jewelry pieces and accessories made from repurposed gems and wire. "For now," Anastasia says, "I work with reclaimed copper, lampwork beads handmade by PJ Beads from CT, Swarovski crystals, vintage beads, sea glass and tumbled stones from the beach... until I find my next fascination of another item that can be reclaimed into jewelry." Recently Anastasia has also created some unique earrings made from recycled aluminum cans!
Probably the most fascinating thing about Anastasia's creative process is that she actually uses reclaimed copper wire from electrical projects for her wire wrapped creations! She strips the electrical wiring, removes the copper, cleans it up & turns it into a beautiful piece of jewelry!
Anastasia has been a huge asset to the vendor team at Vintage Warehouse! You will find her helping out with Door Prizes during our seasonal markets and carrying items in the store for customers most Second Saturdays.
Be sure to follow her on social media and stop in the shop to see what all she has to offer!


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Kelly Reilly is rumored to be naked on next week's episode of Yellowstone. Kelly supposedly strips naked and bathes in a water trough. Then Kelly gets out and walks naked to the house in front of a bunch of people. Wendy Moniz might also have a nude scene of some sort in this episode.
In casting news, hearing Taylor Russell from Netflix's Lost in Space has been cast in Waves. There's supposed to be several nude scenes in the movie. There's another female role that might have some sex scenes and that's rumored to goto Alexa Demie from HBO's Euphoria.


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White Sox -vs- Blue Jays 07-28-2007
A much better effort by the Sox. They won 2-0 over the Toronto Blue Jays. Highlights include the MLB debut of 2nd basemen Danny Richar, his first two hits and the game winning home run by rookie Jerry Owens. It was Owens' first career MLB home run.Read More


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Winning Matte Painting for cgchannel.com matte painting challenge
see more of the process here
Tony Stark's Mt. Pilatus mansion, CGChannel May matte painting FINAL, originally uploaded by gordontarpley.
see more of the process here
Tony Stark's Mt. Pilatus mansion, CGChannel May matte painting FINAL, originally uploaded by gordontarpley.
Camera Move UPdated WIP from Gordon Tarpley on Vimeo.
Original sketch for the architectural layout of the house.
Since this image was to be based on an actual location I did a little research online and found a spot that would fit the description.
This matte painting was actually 2 separate matte paintings, one for the foreground cliff
and one for the background mountains.Which were based on a combination of a panoramic photo from Mt.Pilatus and google earth terrain data that I imported into sketchup then exported to 3ds max which is accurate to all the elevations of the background mountains. (but not recommended, the time to cleanup the geometry was substantial!)
and the house model
color coded wireframe to show the 3 main elements...
All of the elements, along with velocity, zdepth passes and some extra atmosphere, were composed in Nuke.
Other stuff that went along with this project...
a video made with debut while modeling one of the helicopters used in this scene...
Modeling the AW139 from Gordon Tarpley on Vimeo.
and an quick photoshop doodle based on the location for this piece
View From Mount Pilatus speed paint from Gordon Tarpley on Vimeo.


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It is very exciting to share that Filming Part One: Bristol Bay Preseason, a preview of Tails from Bristol Bay, is now available on the Preview page of the film's website!
When Randall Peck, Director of Photography, got back from two weeks of filming with Elijah Lawson in Alaska he put together a one minute clip to give us a feel for what it is like to get a fishing boat ready for the coming Bristol Bay fishing season. Filming Part One: Bristol Bay Preseason captures the faces and places shoreside before the fleet takes to the water. Check it out on the website and let us know what you think!


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HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins
Apoptosis, Cancer and Development Laboratory, Lyon Cancer Research Center, INSERM U1052-CNRS UMR5286, Claude Bernard University Lyon 1, Lyon 69008, France
Author to whom correspondence should be addressed.
Cancers 2014, 6(1), 333-365; https://doi.org/10.3390/cancers6010333
Received: 11 November 2013 / Revised: 3 January 2014 / Accepted: 17 January 2014 / Published: 7 February 2014
(This article belongs to the Special Issue Heat Shock Proteins in Cancer: Chaperones of Tumorigenesis)
AbstractHuman small heat shock proteins are molecular chaperones that regulate fundamental cellular processes in normal unstressed cells as well as in many cancer cells where they are over-expressed. These proteins are characterized by cell physiology dependent changes in their oligomerization and phosphorylation status. These structural changes allow them to interact with many different client proteins that subsequently display modified activity and/or half-life. Nowdays, the protein interactomes of small Hsps are under intense investigations and will represent, when completed, key parameters to elaborate therapeutic strategies aimed at modulating the functions of these chaperones. Here, we have analyzed the potential pro-cancerous roles of several client proteins that have been described so far to interact with HspB1 (Hsp27) and its close members HspB5 (αB-crystallin) and HspB4 (αA-crystallin). View Full-Text
Keywords: human small Hsps; HspB1; HspB5; HspB4; Hsp27; alphaA-crystallin; alphaB-crystallin; clients; cancer►▼ Figures
Graphical abstract
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
Share & Cite This Article
MDPI and ACS Style
Arrigo, A.-P.; Gibert, B. HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins. Cancers 2014, 6, 333-365.
AMA Style
Arrigo A-P, Gibert B. HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins. Cancers. 2014; 6(1):333-365.Chicago/Turabian Style
Arrigo, André-Patrick; Gibert, Benjamin. 2014. "HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins." Cancers 6, no. 1: 333-365.
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Washburn's Comfort Series Acoustic Electric guitars combine looks and ergonomics to deliver the ultimate player-friendly instruments. With their unique belly and top carves, these guitars hug the body rather than digging into it and provide a comfortable playing experience whether you're sitting or standing.
The Washburn Comfort Series WCG700WEK-D is the first all solid wood model in the Comfort Series, pairing a Torrefied Sitka Spruce soundboard with solid African Ovangkol sides and back on a Grand Auditorium body. The result is an instrument that benefits from the immediacy and volume of the vintage aged Torrefied top balanced by the warmth and body of Ovangkol, a tonewood with characteristics somewhat between that of Indian Rosewood and Black Walnut. The ergonomic armrest bevel and the body binding are mahogany and contribute to the instrument's instant comfort as well as classy looks.
With its neutral "C" shaped neck, 1-3/4" bone nut, and Graphtech Ratio-Tuned tuning machines, the all-solid Comfort is recognizable and a joy to play. Plugged in, the Comfort shines with its Fishman Prefix Blend system that includes an onboard tuner and allows the use of both the under-saddle pickup and onboard microphone to create warm acoustic vibes.
A hardshell case is also included.CALIFORNIA PROPOSITION 65 WARNING WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov.
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SHAWINIGAN, Que. – The Alex MacFadyen rink from the Silver Fox in Summerside completed play in the 2018 New Holland Canadian junior curling championships on a winning note.
MacFadyen, third stone James Dalton, second stone Leslie Noye and lead Parker MacFadyen outlasted New Brunswick's Liam Marin 12-9 in a seeding round game on Friday afternoon.
Dalton was named one of the recipients of the Performance Brooms Fair Play Awards as selected by the officials.
The Dave MacFadyen-coached MacFadyen rink completed play with an overall record of 4-5 (won-lost).
Two big ends proved to be key for MacFadyen against New Brunswick. The P.E.I. representative scored five in the third end to open up a 7-1 lead, and scored four in the seventh end for an 11-6 advantage.
New Brunswick also finished with a record of 4-5.
In women's play, the Lauren Lenentine rink from the Cornwall Curling Club gave up a pair of three-enders in a 7-1 loss to Quebec's Laurie St-Georges (8-2).
After going 5-1 in round-robin play, Team Lenentine qualified to play in the championship round.
Lenentine, third stone Kristie Rogers, second stone Breanne Burgoyne and lead Rachel O'Connor completed play with an overall mark of 5-5. Pat Quilty coaches the rink.


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Tuesday - Sunday 11am - 5pm Wednesday 11am - 8pm Monday closed
The administration is open:
Monday to Friday 10am - 4pm
Note: Due to the installation of the exhibition 'Leonard Cohen: A Crack in Everything' the museum is closed for visitors 16 September to 23 October 2019.
GL STRAND offers guided tours for groups, companies, school classes, and other interested groups both during and after opening hours.
The guided tours are presented by art-historians.
The prices below are exclusive entry fee. During some exhibitions a custodian fee is added to the price of the tour.
Private tour in English or other foreign language, 50-60 minutes: 750 kr.
Tours for school classes in English or other foreign language,50-60 minutes, weekdays 11-17: 550 kr.
Possible custodian fee: 200 kr.
For further information and booking please contact us; P / 3336 0260 or E / email@example.com


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Joe Marcinek is anything but conventional. He is an artist with a vision. A musician who not only embraces challenge but thrives on it. Like most Jazz composers, he firmly believes in the concept of improvisation. So much so that he uses a revolving cast of players for each and every one of his performances. An approach that has awarded him much critical praise and notoriety. So much so that he and his band recently performed for former president Bill Clinton's Clinton Global Initiative at the Field Museum in Chicago. It takes a very brave, self-assured musician to welcome the unknown the way he does. Playing shows with new musicians on a nightly basis could be viewed as a terrifying, daunting task for most, but not for him. He does so because he openly states that he loves being kept on his toes. He views it as a tool of precision.
Shockingly, his band's latest release, Slink does not reflect any of this ideology. This is a direct affair, a straight up Jazz-Funk album. It is melodic and honed in from the get go. Opener "George Washington" features an insanely memorable guitar line and equally notable bass break downs. "Bernie" a tribute to the late, Bernie Worrell of P-Funk fame, is a steady synth driven gallop which will have you incessantly tapping your foot. Oddly enough, Bernie is the man himself behind the keys. The track was recorded shortly before his passing. "Everyone Has Their Days" uses the saxophone and more importantly its playing by Nicholas Gerlach to guide the ship deeper into the melodic waters. Here the band sounds like a well balanced mixture of smooth jazz and freaky funk fusion. At times they sound like what I imagine a jam session between Miles Davis 70's electric band and the Joshua Redman Band would sound like. Many tracks feature the latent funk of the former and the melodic directness of the latter.
I find it very exciting that a musician who prides himself on improv and the unknown in a live session can go into the studio and make such a decisive, literal album. The best stories always have two sides. This one will have you dancing in your head and with your feet.
Author: Colin Seymour


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Rethymno – Roustika - Bale
Active 56 klm. / Road Bicycle
This is a large circular route in western Rethymno. It passes through many traditional villages and passes through some of the most beautiful areas of the prefecture. After Atsipopoulo, Prines, Gonia and Agios Andreas, the beautiful provincial road leads southwards to Kalonychti, Roustika and Moundros, finally reaching Kali Sykia, having first crossed a beautiful valley. It then passes through Agios Ioannis westwards, Palioloutra, Agouseliana and Agio Vasilio, reaching the crossroad of Bale and the main road that leads to Rethymnos.


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I have received several inquiries about purchasing my paintings. YES I am selling the original paintings. If there are any that you are interested in, please do contact me at firstname.lastname@example.com.
I am hoping to use the sales of my paintings to offset bills accumulated from health issues over the years.


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Last weekend the Northwest had a preview of summer with some unusually warm temperatures. So we invited some friends, packed our gear and headed through the farmlands of central Washington, to Steamboat Rock State Park. Michael and Micah (Park Ranger & Marine Biologist) joined us on this 4 hour drive to the fringe of the desert.
While hiking, my eyes are usually on the lookout for natures treasures. I have a small collection of rocks and feathers at home. While we were hiking around, Micah found me a beautiful peach crystallized Agate. Thanks Micah!
ScenicBoys: Steamboat Rock State Park 09 from scenicboys on Vimeo.
Next weekend is our Beltane camping adventure and also Garet's 28th birthday. We're so glad that the camping season is finally here!


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A lot of folks build nice wood projects only to struggle when applying a finish. The trouble is that the instructions on the back of the can are pretty sketchy. Here's what they don't tell you, and don't worry, it's no big deal. Follow these steps and you'll leave the wood glowing and the surface buttery to the touch.
First a bit of context. Basically there are two types of finishes: thin oil finishes that make the wood pretty but don't build up much protection, and film finishes like polyurethane and shellac that also beautify the wood but also build up a protective layer. Choose a film finish for any project that will see some wear and tear, like the coffee table in this blog.
Polyurethane is the easiest film finish to use. First of all, choose the quick-drying, oil-based kind. The only reason to use water-based poly is if you want the wood to end up whiter looking (water-based dries very clear, but isn't as durable; oil-based is tougher but has a slight yellowing effect, which is nice on most woods.) Secondly, choose the satin type. It won't end up shiny and sticky looking like gloss poly does.
After that, the main keys to success with any finish are all about sanding–before you apply it, and between coats. Get that right, and watch for drips along the way, and you'll be amazed at how good your new project looks. Here's the path to happiness.


text: DigitalLinkedIn Tweaks Privacy PolicyOnline privacy has been a hot-button issue of late, and LinkedIn is doing its part to address users' concerns, announcing two changes to its privacy policy.By David Cohen|June 13, 2011 ShareBy David Cohen|June 13, 2011 Share Online privacy has been a hot-button issue of late, and LinkedIn is doing its part to address users' concerns, announcing two changes to its privacy policy.The professional networking site will now allow users to opt out of being mentioned in ads generated by their recommendations of products or services on company pages, and LinkedIn said user names and images will not be provided to advertisers.And starting in August, users who share content with their networks using LinkedIn's professional plug-ins will be able to opt out of sharing any information with LinkedIn when those plug-ins load.A full revision to LinkedIn's user agreement and privacy policy will be available later this week.Director of legal, product Eric Heath posted on the LinkedIn Blog:One of the key ways social media helps businesses grow is through word of mouth. On LinkedIn, one of the ways we facilitate that process is by letting you recommend products and services you use on company pages. The effectiveness of these recommendations is related to the people in a trusted network that it is shared with, and one of the upcoming privacy policy changes lets us share your public actions, like recommendations, following companies, etc. on the site with your business network in a commercial context such as an ad.Moving forward, you'll be able to opt-out of being mentioned in any of these ads. Most important, we do not provide your name or image back to any advertiser when that ad is served.Additionally, we recently launched updated versions of our professional plug-ins for publishers on the Web. Now you can share articles and information with your LinkedIn network directly from any site you are viewing. To provide transparency and added control, starting in August 2011, we will be giving you the ability to opt out of any information (e.g. impression data) that may be sent to LinkedIn when those pages load in your browser.Of course, there are other changes to the documents that we urge you to read through, and we will shortly provide you a summary of changes to help you find where the changes are. We know these documents are detailed, but we want to encourage you to look at them once they become available (we'll update this blog post) so you better understand our evolving privacy policy changes, as well as how LinkedIn treats your data.We've always worked hard to earn our members' trust, and we'll continue to provide you with clear controls around your LinkedIn information. Sharehttp://adweek.it/2kAPL56 copy Adweek Adweek


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3 Ways to Become the Thought Leader in Your Market
One of the biggest challenges of building a following and an exceptional online reputation is attracting an audience: first, how to develop content that people want to read, and second, how to automate this material's distribution to influencers in your network.
Article Highlights:
- You are in the information and expertise business, not in the selling business.
- Develop content that is valuable to your audience.
- Use papercheck.com to proof your content.
- Push marketing by email and social media really works.
- Don't write about you: write about what your audience wants.
1. Content is king!
The web has fundamentally changed the way businesses grow and interact with their clients and prospects. Search engines crawl your website and other websites looking for content that they can use when their users search for specific key words. If you are creating content that they think is valuable, you will rank higher in their results. The more satisfied Google's searchers are with a certain search result, the more likely Google is to drive ad revenue to that user. Google, Yahoo, and Bing also watch what content is being read and shared on social media sites. The more popular your content, the higher your "social relevance" ranking.
Okay, so what does that mean to tax and accounting professionals?
Develop content that is valuable to your audience. You are in the information and expertise business, not in the selling business. So don't try to game the system by sharing articles that are promotional rather than educational. Content that builds your online authority will build your brand as well. Cover issues people have questions about: healthcare changes, DOMA, and strategies for minimizing tax liability. These will get read and shared the most on social media. If you find articles on the web that you can add your expertise to, comment on them. Sometimes you can even add a link back to a blog article you have written, which can drive traffic. Bottom line: get out there to get noticed.
And please get your articles proofed. I use papercheck.com. You would be shocked how many professionals add articles with obvious typos.
2. How will they know if you don't tell them?
One of the biggest issues I find when consulting with clients is their use of email and social media to engage with their audience. These are both forms of push marketing, as opposed to pull marketing. If you are not engaging your clients directly, they will be missing out on tips that could save them tens of thousands of dollars. This means lower satisfaction and missed referral opportunities. The stronger your relationship with clients, the higher your fees, and the better your chances of increasing your army of influencers.
One of the biggest misconceptions about the web is that, once you've published new content, Google automatically picks it up and indexes it. This is true if you are a highly ranked and trafficked site, like cnn.com. But your site most likely does not fit that category. This is why it helps to share your content on other sites, so Google can follow the links back to you.
3. Know your audience!
One of my favorite websites is copyhackers.com. Joanna and her team are very good about describing what works in writing copy. One of her first tips is to write to your audience, not to write about you. This seems obvious, but I still need to remind myself that readers are reading my content only because they want to improve something or solve a problem. This applies when you are writing to become the thought leader on a subject. Think the way your client does. What problems do they need to be solved? They may react to a number of approaches: fear, reward, or the word free. Whatever the approach, though, make sure you stop writing about yourself and more about them.
If you develop great content that people want to read, write it in a voice that talks to your reader rather than talking about you, and you push that content out to your audience via email, social media, and blogs, then you are well on your way to becoming the thought leader in your field.
Lee Reams II
I am a marketing junkie who has spent the last 20 years developing and executing "best in class" word-of-mouth marketing campaigns. With over 10,000 happy clients I think we are on to something. The explosion in web marketing and social media have redefined the way independent professionals market their practices. Follow my blog to see if you can take some of our actionable ideas to market your own practice.


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Scheduling Your Appointment
Our goal is to be an affordable option for all people across Texas and Pennsylvania. At this time, we do not accept insurance. For those who qualify, a sliding scale is available.
Free Consultation
A free consultation is the first step for everyone. You'll have the opportunity to connect with the SLP, have any questions answered, and make sure that this is the right fit for you! This will be our time to discuss the overall outline of services, expectations, and what transformations you're wanting in your life.
The comprehensive assessment covers all areas of speech, language, and voice, as well as learning about you and your personal goals. This process aims to be as exhaustive as possible, and will take about an hour to complete. All factors will be taken into consideration when developing your own, unique plan for services. After the assessment, the SLP will analyze the data collected, and then reach out once your personal plan is ready for review. And then, get ready to transform your life!
Sessions are generally 45 minutes, and are 1:1 practice sessions focusing on your specific goals and targets. Frequency of sessions and the total duration of your treatment plan will vary depending on every client's specific needs and preferences. Sessions incorporate evidence-based techniques and clinical knowledge and skills to work with you to help transform your life.
Business Communication
Business communication sessions are sold in bundles. Depending on your specific needs, whether as an individual or company, the amount of sessions will vary. Bundles cover a variety of topics including: effective communication in the work place, interviewing skills, public speaking, non-verbal communication, report writing, and many other various ways we communicate in the workplace. Schedule your consultation today for a free estimate on how to improve your business communication.


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Status & DNS Servers
|ns1.register-this-domain-name.com ((DOES NOT EXIST))
ns2.register-this-domain-name.com ((DOES NOT EXIST))
|Paul Robinson
|Paul Robinson
|Uber Creative Ltd, 7-15 Rosebery Avenue, London, London, EC1R 4SP, GB
More Info
Domain Name: NUDGING.ME Registry Domain ID: D108500000002063944-AGRS Registrar WHOIS Server: Registrar URL: http://www.meshdigital.com Updated Date: 2016-06-20T12:43:16Z Creation Date: 2011-07-04T12:26:36Z Registry Expiry Date: 2017-07-04T12:26:36Z Registrar: Mesh Digital Limited Registrar IANA ID: 1390 Registrar Abuse Contact Email: Registrar Abuse Contact Phone: Domain Status: clientDeleteProhibited https://icann.org/epp#clientDeleteProhibited Domain Status: clientTransferProhibited https://icann.org/epp#clientTransferProhibited Domain Status: clientUpdateProhibited https://icann.org/epp#clientUpdateProhibited Registry Registrant ID: MNT7B120683084 Registrant Name: Paul Robinson Registrant Organization: Paul Robinson Registrant Street: Uber Creative Ltd Registrant Street: 7-15 Rosebery Avenue Registrant City: London Registrant State/Province: London Registrant Postal Code: EC1R 4SP Registrant Country: GB Registrant Phone: +44.7967271826 Registrant Phone Ext: Registrant Fax: Registrant Fax Ext: Registrant Email: email@example.com Registry Admin ID: MNT7B120683084 Admin Name: Paul Robinson Admin Organization: Paul Robinson Admin Street: Uber Creative Ltd Admin Street: 7-15 Rosebery Avenue Admin City: London Admin State/Province: London Admin Postal Code: EC1R 4SP Admin Country: GB Admin Phone: +44.7967271826 Admin Phone Ext: Admin Fax: Admin Fax Ext: Admin Email: firstname.lastname@example.com Registry Tech ID: MNT7B120683084 Tech Name: Paul Robinson Tech Organization: Paul Robinson Tech Street: Uber Creative Ltd Tech Street: 7-15 Rosebery Avenue Tech City: London Tech State/Province: London Tech Postal Code: EC1R 4SP Tech Country: GB Tech Phone: +44.7967271826 Tech Phone Ext: Tech Fax: Tech Fax Ext: Tech Email: email@example.com Name Server: NS1.REGISTER-THIS-DOMAIN-NAME.COM Name Server: NS2.REGISTER-THIS-DOMAIN-NAME.COM DNSSEC: unsigned URL of the ICANN Whois Inaccuracy Complaint Form: https://www.icann.org/wicf/ >>> Last update of WHOIS database: 2017-02-07T10:57:04Z <<< For more information on Whois status codes, please visit https://icann.org/epp Access to WHOIS information is provided to assist persons in determining the contents of a domain name registration record in the registry database. The data in this record is provided by The Registry Operator for informational purposes only, and accuracy is not guaranteed. This service is intended only for query-based access. You agree that you will use this data only for lawful purposes and that, under no circumstances will you use this data to(a) allow, enable, or otherwise support the transmission by e-mail, telephone, or facsimile of mass unsolicited, commercial advertising or solicitations to entities other than the data recipient's own existing customers; or (b) enable high volume, automated, electronic processes that send queries or data to the systems of Registry Operator, a Registrar, or Afilias except as reasonably necessary to register domain names or modify existing registrations. All rights reserved. Registry Operator reserves the right to modify these terms at any time. By submitting this query, you agree to abide by this policy.
Data updated: 2017-02-07 10:58:12


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That's the title of Wieden + Kennedy London's new pan-European campaign for Honda, which uses spaceflight as a visual metaphor for bold innovation.
Actually, the metaphors are mightily mixed in the campaign's launch film, which packs plenty of imagery and action into its 90-second run time, referencing Honda's heritage across consumer automobiles, Formula 1 racing, aviation, robotics and more.
Read more on AdWeek.


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"Modern" and "Sleek" are two words you wouldn't normally associate with dim sum joints in Chinatown. But, that is what you get when you enter Full House Cafe, a Chinatown restaurant specializing in Hong Kong dim sum and Shanghai cuisine. This restaurant caters more towards Americans, and if you are seeking an introductory into dim sum, this could be the spot for you. There are no carts wheeling around here, instead, you can order from an extensive menu of delectable bites. I did a little tasting two weeks ago, and was pleasantly surprised with the tasty fare coming out of the kitchen here.
My favorite dish of the night was the Dong Po Pork ($13). Glistening and delicious pork belly served over greens, and accompanied with some buns, so you can make your own little pork bun sandwiches. Order this dish.
The pork soup dumplings ($6.25) here aren't the best I've had, but still a must order. They are definitely satisfying.
A dish of chicken flavored with black pepper and jalapeño was fabulous. Great flavor, with a great kick.
Beef with black pepper sauce ($18.95) was also delicious.
So if you are seeking some dim sum and Shanghai cuisine in a modern setting, check out Full House Cafe. You might not see the Olsen twins, but you'll definitely find some delectable bites.
Full House Cafe
97 Bowery (bet. Hester and Grand)
New York, NY 10002


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... from Lorraine:
I created my first dwelling at age 8 using table cloths quickly snatched from my mother's linen closet, a broom handle for the "teepee mast", string, electrician's tape, and cabinets made from some cardboard boxes from our basement, with the intent of hosting elaborate tea parties there with my sister. In my middle school years, I often made 'rounds' after school with my father visiting his residential construction sites, loving all the sensory experiences of fresh cut lumber, and saws and hammers creating a couple's, or families', new dwelling. Entering college I set on a course to pursue holistic design at Auburn University with a dual major in architecture and interior design. I wanted to help people create personal environments from the outside to the inside, that reflected the way they wanted to live and play. With this focus on the personal environment, I formed my thesis on the psychology of design and color to demonstrate how we can create a built environment, drawing from the elements in nature that speak to us, and help us feel healthier and "right".
And so after over 22 years of helping people create places and spaces that FEEL RIGHT to them, shaping their environment to fit their personalities and lifestyle, I 've come to believe that deep within us is a desire to thrive where we dwell. Ultimately, we are seeking that sense of place that feels right to us, where we can live, play and enhance our personal relationships seamlessly. In this pursuit, our intuition, or 'gut' gives us a thumbs-up or thumbs-down in response to the world around us. However, it is through discovering our unique intuitive nature -- the composite of our heart's intentions – that we begin to understand WHY some things feel right to us and other things don't.
This is what I call HEART CENTERED DESIGN and is the heart of INTUITIVE dwellings.
It's a new type of custom.
So, whether you seek to create a modern farmhouse with clean lines, a historically inspired home with a family focus, a summer retreat that immerses you into nature, a one of a kind artful structure or interior, renovate a suburban home with good bones or update an urban townhouse with a hip vibe, it is about YOU in every way. Together we will help you discover and foster a deeper connection with your personal environment, bringing together those elements in life and nature that define YOU in your world, creating that unique dwelling that helps you FEEL RIGHT WHERE YOU LIVE.
Let's begin together.


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1,000 signatures reached
To: Trustees for South Yorkshire Women's Aid
Stand Up for Louise Harrison South Yorkshire Women's Aid
We the undersigned call upon the Trustees of South Yorkshire Women's Aid to drop the proposed threat not to renew the contract for Louise Harrison. Instead we call upon the Trustees to work with Louise and the campaign in order that her hard work to secure funding for the service are successful and enable the service to continue.
Why is this important?
****BREAKING NEWS: Grassroots activist for the 'Save South Yorkshire Women's Aid' campaign, Louise Harrison, is facing dismissal from her role at South Yorkshire Women's Aid ****
The shocking news was sent by post to Louise just before Christmas. Louise is on a fixed term contract which would need to be renewed at the end of the year, the trustees make allegations in the letter which put Louise's renewal at risk.
Louise has been organising to try and save South Yorkshire Women's Aid since Doncaster Metropolitan Council said they will not renew funds to SYWA when they run out in December 2017, as the council has made cut backs from the voluntary sector.
South Yorkshire Women's Aid was initially set up on a grant of £30,000 in January 2017 from the council after the previous Doncaster Women's Aid was closed due to lack of funding in March 2016. The small grant of £30,000 was hard fought for by Louise and others in 2016.
The service currently runs on two part time staff, a third part time staff member is on maternity leave. The service has around 40 hours of staffing provision per week. Whilst the service has few resources and staff, it does lifesaving work for women and girls in Doncaster. The services runs two therapeutic courses, a free phone line, 1 to 1 advice and advocacy. Louise had been trying to raise money for the already struggling service.
Louise was off sick with exhaustion, stress and a recent family bereavement when she received the letter from the Trustees. The letter insinuates that some of the Trustees are unhappy with the service she has been providing women.
Louise was not only instrumental in setting up the service but also brought in the majority of new funds to stop the service from closure. However, we are not surprised that this has come at a key point in the campaign to save the service. Since the campaign to save the service began, Louise and volunteers of the services have vocally opposed the council's decision to not fund the service past December 2017.
The trustees however have opted to attempt to water down the campaign and work to silence Louise and others attached to the service, by putting pressure on Louise and others to stay positive about the council.
The trustees who are members of the labour party have clearly been put under pressure from the council and have bought the right wing labour line of the council - that Louise and other campaigners are what is scuppering the chances of SYWA funding.
A witness working on a big lotto bid for SYWA was present at a meeting with a Labour affiliated SYWA trustee and MP Rosie Winterton where Rosie alluded to volunteers and staff militantly leading a campaign to save the service and that this could make the service unattractive for funders and clients.
However Louise has received huge support from clients who were kept up to date by Louise about the funding status of their service. Clients asked to write letters to Ed Miliband, one ex-client in particular has been central to the campaign to save the service.
The trustees are working to distance SYWA's image from campaigners. We think that it is a mistaken belief of the trustees that they and campaigners should placate the council. If all it took to save women's specialised domestic violence services was difficult discussions with the council then we wouldn't see VAW services disappearing from our towns and cities. This weak position could lead to SYWA trustees now in charge of negotiations with the council, folding to the position of the council that their 'is no funds'.
The argument of lack of council funding has been at the heart of the fall out between campaigners fighting to save SYWA and the council. From the start Louise and other campaigners refused to accept that council had no money to renew the £30,000 SYWA grant. The campaign highlighted the 91 million in 'usable' council reserves and the inflated pay of the council senior officials (the pay of the top ten senior council officials equates to over £1 million – all of which can be found online).
Louise said "I am deeply shocked about the inference in the letter that I have let women down. For the past 7 months I have worked largely unpaid to try to secure funding for our service with little or no support from some of the Trustees. It is deeply upsetting to read that I would do anything that would harm the women who desperately need our services."
Only a week ago Labour Shadow Chancellor, John McDonnell, came out in public support for the campaign to save the service (see quote below). The three Doncaster labour MP's and the labour council should now put that support into action and back Louise as a staff member at SYWA and all the community campaigners in fighting for their service.
A Stand Up For Louise Harrison Campaign Group are mobilising quickly mobilising amongst supporters.
1. For further information please contact Amy Cousens: firstname.lastname@example.com 07517207061
2. Details for the petition are as follows: https://you.38degrees.org.uk/petitions/stand-up-for-louise-harrison-south-yorkshire-women-s-aid
3. "I want to pass on a solidarity message to South Yorkshire Women's Aid campaign. Your campaign is an inspiration. I will liaise with the three local Labour MPs and Doncaster Council to seek to save this much needed service. I give this pledge that a Labour Government will ensure funding for these vital women's services will be provided because "Women's lives matter solidarity - John McDonnell Shadow Chancellor"


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Which way to the Booker?
With his Reluctant Fundamentalist being short-listed for the Booker, Mohsin Hamid speaks his mind to Shaikh Ayaz.books Updated: Sep 23, 2007 08:32 IST
Seven years ago, he was big with Moth Smoke. Now with his second novel, The Reluctant Fundamentalist, he has
been shsort-listed for the Man Booker Prize. Born in Lahore, he was in New York for a while and now lives in London with his wife. A brand consultant by vocation, here's Mohsin Hamid in an online talkathon with Shaikh Ayaz.
How hopeful are you of The Reluctant Fundamentalist romping home with the Booker Prize?
Ah, it would be nice if I get the Booker. But I'm not particularly hopeful. I'm just one of the six authors.. it makes sense to keep one's expectations low.. that's the way I'm looking at it.
Ian McEwan's On Chesil Beach and especially Lloyd Jones' Mister Pip are top favourites. Do you think you'll give them a tough fight?
It's not a sport.. it's not like cricket where I can bowl a really fast one and dismiss Mister Pip. Booker is not about the best book alone, it's about what the judges like too. I'd be lying that I wouldn't feel good if Iwon.
On the day of the 9/11 tragedy in New York, you were in the U K. How did your novel invest authenticity in the subject of the disaster?
I've lived in New York for four years. I've been to Princeton University. I wrote the manuscript of The Reluctant Fundamentalist seven times over. As a writer, I connect to both Lahore and New York. The novel has been described by some as an anti-American harangue. It's not. The principal protagonist, Changez, loves Pakistan as much as he does New York, where he has worked. He is also in love with an American girl. The narrative is much too complicated to be anti-American.
How was it received in the US?
Well, it was a bestseller there. Changez seems to have a constant fear about a reprisal by India against Pakistan after the Parliament attack in 2001.
In away, isn't the novel anti-Indian because of this paranoia?
Look, I want to be absolutely clear on this.. it's not anti-India at all. As a Pakistani, when I look back to those days, India's position was certainly aggressive towards the government of my country. Anyway, this doesn't form a major
portion of the novel. Through my writings, I have constantly suggested there should be peace between the countries,
because the bottom line is that Indians are like Pakistanis.. and vice versa.
You travel on a Pakistani passport.. has the behaviour towards you changed in anyway after the success of The Reluctant Fundamentalist?
That's an interesting point. I travel mostly with a British passport nowadays.Once I was in Delhi with a Pakistani passport. So I had to visit the police station every morning. Consequently, I could work.. write.. meet people only in the evenings. I call this the passport caste system. Such problems arise mostly for citizens of poor countries. And then of course, there's been this all-pervasive suspicion of Muslims lately.
Although Indian authors are experiencing their big moments in literary circles, does it bother you that Pakistan hasn't thrown up literary geniuses in recent decades?
Yes, that does bother me. In the 1980s, there was a sudden burst of Indian writers on the literary scene. But things are changing in Pakistan. I get many manuscripts from budding Pakistani writers every day. There will be a literary
boom among writers of my country sooner than later.
You're 36 now. How difficult has it been to straddle the east and west?
I don't think it's easy living anywhere in the world. A guy from Delhi goes toMumbai and settles down.. a girl leaves her parents' home to live with her husband and in-laws. There's always this period of transition.. some are easy, some aren't.
Don't you feel a sense of belonging to Lahore?
(Laughs) I belong to Planet Earth. If you insist, I'd say it's like asking which of your friends do you belong to.. you belong to each one of them equally. Right?
Living in London, with the well-paid job of a brand consultant, does Pakistan's politics bother you really?
Oh, of course it does. As a writer, I'm part of the debate on Pakistan's politics. I hope and pray that Pakistan re-establishes its democracy. The question is—how we can get there. It's really hard to predict what will happen next in Pakistan, whether General Pervez Musharraf will step down or martial law will be imposed.. my dream is to see a stable Pakistan.
Ever felt like joining politics instead of theorising?
I don't think I can run the house by doing that. Politics is about cutting power deals.. horse trading, to be precise. Maintaining one's ideals would be difficult in politics.
Right now, there's a leadership crisis in your country. Musharraf's government hasn't done any good for the people. On the other hand, Nawaz Sharif and Benazir Bhutto face charges of corruption. Who should lead the country anyway?
There are leadership issues.. the choices are unattractive. I wish I had a clear answer.. except that let the people of Pakistan take on the initiative and produce new leaders. In any case, paradoxically the dictatorship in Pakistan has
allowed considerable freedom of expression. Pakistan newspapers and television are much more critical of our government than Indian media is of yours.
Which Indian authors do you like?
I don't think I can take the liberty of making general statements on Indian writing.. it's enormous. There are hundreds of writers in India, some of whom I've loved, some I haven't even read. Among the new generation writers, I like Pankaj Mishra, Suketu Mehta and Kiran Desai. They are fabulous writers.
Pakistan loves Bombay movies.What about you?
Frankly, I'm not much into them.. my sister and wife are kind of more clued in. I have seen Sholay, Qurbani and Qayamat Se Qayamat Tak. I watch maybe one or two Hindi film in one or two years.
First Published: Sep 22, 2007 13:10 IST


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How the world has progressed from mailing lists and bulletin board systems. Where is Compuserve?
I continue to find "social networking" fascinating. I put the term between quotes; it is not as if humans weren't socially networking before the founding of MySpace or Facebook. All these nodes in the world wide web do underwrite that humans are social animals first. The success of the telephone a century ago, the ringtone explosion, Japanese teenagers sending each other grainy photographs on their mobile phones and so on.
Social networking intrigues me both personally and professionally. I live in Rochester, NY but most of my family and many of my friends are elsewhere – personal web sites, Facebook friends, twitter updates all help staying in touch with each other and so over a distance of thousands of miles and six time zones I still know that Gero is stuck in a 3 1/2 hour traffic jam due to a truck accident. I have to say though that much of my family is disappointedly cyberspace-inactive. Professionally it helps maintaining connections with peers in the industry while we all move positions, change jobs – and it adds to a manager's ability to stay aware of the professional well-being of remote colleagues (Facebook status updates can give interesting hints on a colleague's gearing up for a job change). In my usage I try to separate LinkedIn contacts and Facebook friends between professional, work-related and personal respectively although the line is rather blurry.
Facebook, MySpace, Twitter are all so successful also because they feed into the narcissistic tendencies of many of us allowing us, encouraging us to twirl our experiences, our virtues onto the world. I happily do. Yesterday I went on a bike ride. Before the ride I twitter that I am about to do this and I twitter upon return. The pictures from the ride need to be uploaded to my .Mac gallery, to Flickr, to Facebook and I need to write about the ride on this blog. The stats recorded by my bicycle computer are uploaded to BikeJournal. If I read something interesting on cycling or social networking then I need to bookmark that to del.icio.us. And in between I need to worry about my Technorati authority (only 2, what's up with that?). All this easily takes much more time than the bike ride itself.
Am I profiling myself enough? How much would my personal brand gain if I also joined Friendster, Friendfeed, Plaxo, Livejournal? Heard the other day that World of Warcraft is becoming Golf of this millennium – the place where business deals get done. I never played golf so maybe I have a shortcut here?
At the same time email is still a key communication tool. With the 11066 unread emails I have as of this writing, keeping up with all the twitter messages, facebook status updates, flickr discussions etc etc how do you stay abreast of that deluge of information? How do you know what to pay attention to and when? How to avoid being interrupted by each incoming email during writing a paper or software? Last week I unfollowed someone because he was just twittering too much.
An MIT project now implemented at MovableType, Action Streams, can be useful. Action Streams allow you to aggregate and share your actions and profiles around the web in one place. Maybe that can optimize my "post ride"-workflow?Ambient information devices then help you assess the state of information waiting for you. There is the Chumby – love to get a few of those. There's the glowing orb. The cute rabbit by Nabaztag.
For now I am starting in a cheap and simple way. Our Mac Mini is supposed to be our media server but actually spends a lot of its time on my desk. By keeping it in Dashboard mode I can have occasional glances at stock quotes, the weather, San Francisco web cams, IP addresses on our home network, Dutch headlines, Facebook and twitter updates, and a world clock.


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Last Meet and Greet 2018
We are having a Meet and Greet on November 11.
This is a great opportunity to meet our leaders, learn more about our ministry and vision, or find out how you can take your next steps in our church.
We will have some light refreshments and plenty of conversations after the service.
All are welcome to join us!


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Contact us Today: 1-800-951-0777
Product News
Condenser Panels Provide Stable Efficient Operation All Year Round.
Purestream is pleased to offer the "Made for Canada" Winter Condenser Panel for our CWT Process cooling chillers. The Panel restricts airflow to the Condenser Coils and reduces wind effect under Winter Cooling Conditions. The system works in conjunction with the Condenser Fan Motors to control fan speed and thus Head Pressure.
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Elastos | STK Token | Iungo Network
Social: Facebook, Twitter, Telegram
Team: https://www.elastos.org/team
Exchanges: Huobi
Total Supply: 33,000,000 ELA
Elastos is a project which aims to develop a blockchain based operating system with support for decentralized apps. The major advantage of a decentralized operating system will be the ability to stop apps from directly accessing a network. Plus, a peer to peer infrastructure reduces the need for having human intervention especially when the operating system is deployed across a large organization.
Elastos also make acquiring rights for digital products immensely secure and easy. Rights and contracts will be transferred using the blockchain as its backbone. Essentially turning digital information into an asset. Since the operating system and blockchain does away with the need for intermediaries, it will become nearly impossible to forge credentials hence blocking if not completely eliminating efforts to pirate genuine licensed software and information.
Team: https://stktoken.com/
Exchanges: Huobi, CobinHood, IDEX
Total Supply: 500,000,000 STK
The STK token is a project which aims to facilitate real-time point of sales transactions in the real world but using cryptocurrency wallets. The ability to make in-store purchases will speed up the adoption of cryptocurrencies. The company sees itself as being part of a global solution to further the adoption of cryptocurrency commerce in the real world with true borderless transactions.
Currently making purchases via your cryptocurrency wallet requires that the currency is converted into fiat currency based on prevailing rates. However, when the STK token is used it works as an intermediary by first making sure that there is enough cryptocurrency in the wallet like bitcoin, Ethereum, etc. Then the STK token opens a direct line between itself and the point of sales merchant via the STK wallet. So, in essence, the transaction is funded by STK tokens similar to how Ethereum transactions are funded by gas.
Social: Facebook, Twitter, Telegram
Team: https://iungo.network/#team
Exchanges: Kucoin
Total Supply: 62,553,604 ING
Iungo is a project that's working on developing an open source platform which will allow anyone to become an ISP (Local Internet Service Provider) as part of a global WiFi network system. The benefit of this global WiFi network will be the ability to connect seamlessly from anywhere around the world. The service will be secure and provide VPN services too. The project apart from making connecting to the internet easy will also bring the internet to developing parts of the world. ISPs will get paid for their services via cryptocurrency. It can be considered as the Airbnb of the internet service provider world.
As part of the global Wifi network project, Iugo has signed a partnership agreement with Ligowave, which has been offering WiFi internet services in Europe since 2006. It is the fastest growing WiFi equipment manufacturer too. The deal will further the goals of the company's global WiFi initiative.


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The following songs were inspired by the millions of less fortunate people in the world who suffer from "curable blindness". This music is the glue that holds the One World Sight Project together.
Music Files
|One Spirit* – by: Richard Weiss
…the song that inspired the project
Tommy's World – by: Derek Welsh
|* Arranged and sung by Jimmy Hopper


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Natural Remedies for Children Dental Caries The treatment of dental caries consists of the removal of decayed regions of the tooth and filling the cavities.
According to Dr. Lad in the Complete Book of Ayurvedic Home Remedies, yeast infections are a result of a mixed pitta and kapha disorder. It's essential to follow the proper diet, Padove, Page 7 and not increase pitta or kapha.
Useful At-Home Remedies . Colds, Flu, Allergies and Seasonal Immune Support. Yin Qiao: Best taken at first feeling of sore or scratchy throat achiness or fever.
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Medicated cosmetics and other topical acne remedies which contain sloughing agent e.g. benzoyl peroxide, tretinoin, sulphur or resorcinol. Caution should be applied in pregnancy since it may be potentially harmful to the baby. It
Other big name brand to even the home remedies as well. few of my siblings had small acne breakouts once in a while and I would share with them the best acne remedies that were making a little difference in my skin and when they would use them their skin
Promote good digestion and relieve stomach. TakeBesides taking some home remedies, remember that the practicalYou want to know the best treatment of the natural
10 Minute Home Remedies www.NoMoreItchyScalp.com NATURAL OILS TO ASSIST HEALING, DETOX AND STIMULATE
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Above aids in digestion and thus produce less gas readily available at home. One should not take allat once. Instead try the remedy which works the best for you.
Garlic cloves daily is your best defense, but if you must cook it that can stillthis water. It is also very effective home remedy to treat gastritis. . Add a tablespoon of flax
2012 7:02 AM A list of my favorite home remedies: Moistened tobacco for insect and aiding in digestion of food – Mint is a natural
Rebuild cells. (Pricey though) They have the best minerals known. When fibrous foods both will slow they body's digestion down. This will aid in not be so hungry before


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6 Valentine's Day activities for couples
Flowers wither, chocolates are soon forgotten, and presents — no matter how appropriate — won't spark the same joy as the years go by. Shared experiences, however, may well be the most romantic Valentine's Day gift of all.
"Experiences have been shown, through research, to increase in satisfaction as time goes by, whereas a physical gift has the opposite effect of losing its satisfaction," says British expatriate Anne Jackson, a relationship coach with One Life Coaching.
But if you haven't been able to book a romantic trip away for next weekend, there are still several ways to show your love with some wonderful experiences right here in the UAE. Take your pick from our curated selection — we've covered all relationship types.
The thrill seekers
This Valentine's Day enjoy non-stop fun with your loved one at Motiongate Dubai. For just Dh 275, you get a park ticket, a Q-Fast pass so for you to skip the queues, a sumptuous three-course meal, an unforgettable meet-and-greet with Shrek and Fiona, a special gift and unlimited access to rides throughout the park. Offer is valid from Feb 14-16. Visit Motiongatedubai.com for more details
The rollercoaster riders
If your relationship is a lot of ups and downs, you'll enjoy the breathtaking rollercoaster that is La Perle by Dragone at Al Habtoor City. With stunning aerial and aquatic feats, the Middle East's first permanent resident show combines performance art, imagery and technology in an immersive experience. The La Perle Valentine package runs from February 14-16 and includes two Gold tickets, dinner for two with two glasses of bubbly at a choice of four restaurants — all for Dh1,400. Shows are held at 7pm or 9.30pm. Book at Laperle.com
The high-flyers
Take your affair to a new pinnacle with a helicopter tour of the UAE's most futuristic city. HeliDubai allows you to reflect on how far you've come and where you're headed with an aerial tour of the city's progress from Old Dubai to the heights of Dubai Marina and beyond. Flights take off from the HeliDubai Jumeirah Heliport and are available for 12, 17, 22 or 40 minutes. Prices begin at Dh646 per head. Can be booked at 800 FLY (359)
The duellers
Some relationships are a combat sport — and no wonder, since adrenalin reputedly raises attraction levels. Let biochemistry help you along by heading over to the JA Shooting Club for a round of archery, indoor shooting or clay pigeon shooting. So no matter who wins, you can celebrate afterwards with a three-course menu and a glass of bubbly at Shooters Tex Mex Restaurant. It'll only set you back Dh595 per couple. Call 04 814 5555
The altruists
Love doing things for your partner but can't find the time? Or maybe you want to woo someone? Get a professional chef to help you out. Dubai-based Epicure Catering will cook and deliver a three-course meal for two at Dh249 per person this Valentine's, so you can dine in and chill. The firm offers a variety of menus, with dishes such as porcini mushroom risotto, lamb rack and a dark chocolate tart with caramel sauce. Email [email protected] or call 04 347 3808
The Instaromantics
Can't do without advertising your love on social media? You'll want to hurry down (via Google Maps) to the Love Lake at Al Qudra, where you can marvel at Dubai's newest attraction: two manmade lakes in the shape of two interlocking hearts. Take a romantic walk around the water, and stop for a moment in the trees, which spell out the word Love. Further afield you might find Arabian wildlife in their natural habitat. Just please don't play Two Become One on the ride over.


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Hello, I am Miss Young. I received the following email. It is a socalled
"Advance Fee Fraud" letter, where I am promised millions for
my assistance. These stories are all lies, and if I respond, sooner
or later I will be asked to pay a fee. If I pay, another fee will quickly
come up, and it will continue that way until I give up or run out of
money. I will never see the millions, because they never existed.
If you received a similar email, you should go to the homepage to read more about 419 fraud.
Betreff: NOTIFICATION OF CREDIT FROM FEDERAL RESERVE BOARD NEW YORK( Code: (ATM Visa Card-Y2K15)
Datum: Sun, 13 Sep 2015 15:22:11 +0200
Von: "Ms. Janet Yellen" < email@example.com >
An: undisclosed-recipients:;
If you received a similar letter, please ignore it. Do not answer it.
If you do, you will end up on more of the mailing lists used by the
criminals behind this fraud. Read more....
Copyright © 2004-2015 419.bittenus.com. All rights reserved. Updated


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Welcome to Impressions Dental Spa. From the moment you arrive, you'll realize Impressions is like no other. Impressions Dental Spa was created to give you the ultimate experience of escape and indulgence, all while getting your smile enhanced. We invite you to try this unique dental spa for yourself.
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About Guitar lessons
Gus Sinaro owner/founder , has been teaching in fairfield county for over 12 years. His straight forward approach in teaching has made playing guitar fun while covering all the basics and fundamentals of music. Guitar requires discipline, practice and patience such as any other instruments. Gus is a great coach for Rockbands as well sharing his experiences with live performance, stage presence, television performance, songwriting and appropriate usage of amplifiers, pedals and music equipment. Gus and his band Symphony of Malice have played internationally and has opened for the following national acts- Trivium, Korzus, Drowning Pool, Eye Empire After the Burial. His Band has also been featured on the Hit Brazilian television show- Show Livre. Gus is also endorsed by Hughes and Kettner amplifiers and BBE sound pedals. Lessons are available 7 days a week in Greenwich, Stamford, Rye, Old Greenwich, Darien, New Canaan, Norwalk .