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Interview: Marisa Emma Smith and Nyla Carpentier/
"At Alley Theatre, we tend to do things that are unconventional in their staging, and we like to tell stories that aren't often told—socially relevant things that don't often get exposed through social media," says Marisa Emma Smith, co-director of Alley Theatre's adaptation of the award winning German radio play, The Ridiculous Darkness, by Wolfram Lotz.
As Marisa says, this piece will be nothing but unconventional. Lotz's script is a comedic modern mash up of the classic novel Heart of Darkness and the film Apocalypse Now, engaging with how the cultural and racial 'other' is viewed and treated both within and separate from the context of war. The adaptation that Marisa Smith and Nyla Carpentier have co-directed is much more than your average theatre experience; the production has participation from various organizations and groups within Vancouver, such as Tetsu Taiko, Street Vendors Society and the East Van Powwow Crew, making for an interdisciplinary, multi-faceted, collaborative performance, at times featuring more than 40 people onstage, some from various non-theatrical backgrounds.
"What was it in your directing practice that brought you to this piece?" I ask Marisa and Nyla. Marisa and her husband Daniel Arnold, who adapted The Ridiculous Darkness from a radio to stage play, experienced a show by Public Theatre in New York a few years ago.
"It incorporated outreach and participation from all of five boroughs in New York," says Marisa. "Pop-and-lock kids, drag queens, flamenco dancers, and it was just this great feeling of being part of this beautiful circle of humanity. We walked out of that with tears in our eyes." Shortly after, Marisa and Daniel were introduced to Lotz's play. "The script itself has all of these relevances to relationships around colonialism and imperialism in a very current context. It felt relevant on a larger world scale. Whereas Alley theatre's work is more locally minded."
However, despite the worldly status of the play, an exciting part of the adaptation process was Lotz's personal support; he articulated in his playwright notes that anyone who adapts this to the stage is strongly encouraged to make any changes in order to keep the piece relevant to what they envision. Therefore, Daniel and Marisa were able to ask of the piece: "Why is it necessary to bring The Ridiculous Darkness to Vancouver? That's usually what we start thinking about in our work," says Marisa. "What makes it relevant to our specific local audience?"
Marisa comments: "We live in this very multicultural place that has so many different people, and yet we are kind of cut off from each other. There are some invisible lines that we don't talk about, but they're there—and it's not even a cultural thing, its economic, and something to do with the way that we relate to each other in Vancouver, and how we are kind of unfriendly."
As a collaborate journey, The Ridiculous Darkness seems to challenge the familiar notion of local theatre. With this piece, the theatre production isn't isolated to the stage; rather, is heavily reliant on the different connections within the community of Vancouver as it creates a dialogue about how we as a Vancouver community view and communicate with those labelled as 'other'. It was this collaborative approach to the this production that formed Marisa and Nyla's directorial partnership. Nyla had always been interested in directing, but had never had the opportunity to do so on such a large scale. She initially auditioned as an actor, bringing with her so many rich ideas, and Marisa and Daniel realized there was no other role for her but co-director.
When asked about the communication aspect so integral to the conception of this piece, Nyla responds: "Being Indigenous and mixed heritage myself, I have a very strange relationship with colonialism and I am still trying to figure that out within myself. But one of the things that I said to Daniel and Marisa is, don't be afraid to ask questions and in terms of Indigenous people, don't be precious with us. We have a sense of humour for a reason, that's how we survived genocide."
As an Indigenous artist and performer, Nyla feels that not only has this opened up dialogue between communities, but within the Indigenous community as well.
"It makes us realize when we talk to different communities, that it isn't simple; it is complex, but you can come to an understanding if you take the time to listen and have those conversations."
This is a piece meant to probe the audience with questions, and not the easy kind. Nyla says, "There are times when we go into the absurd with this piece, and people may be very challenged by what they see, but the next moment they may be laughing their heads off." This satirical play engages with challenging content not to illustrate what is right and wrong within our cultural conversations but rather, as Nyla puts it, "to get past all of the complex spiderwebs of emotion, the heart, and of communication and finding that understanding and acceptance between people who are different."
When I ask Marisa what kind of dialogue she hopes will emerge from this production, she says it could be the smallest, or most subtle. "We've gone too far with our politeness in Canada, we've gone too far without even being interested in other people's culture, or culture in general. It's like we are afraid of it or something. So really, I hope for a letting go of those funny little fears that we have."
The Ridiculous Darkness runs from November 11 to 19, at The Annex. Tickets/more information can be found here.


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Every week I like to feature an Australian writer and illustrator in PASS IT ON.
The illustrators' interviews, once they have been featured in the ezine, are uploaded onto this blog.
The writers that I've interviewed don't have a blog of their own so I thought I might upload their interviews here. I won't be able to go back to the beginning but I hope to fill this space with interesting insights into some of our wonderful writers.
So here we go, please meet….
Elizabeth Kasmer
This interview first appeared in PASS IN ON on Tuesday 21st March 2016 – issue 578
Tell us a bit about yourself
I was born and raised in Brisbane but have also been fortunate enough to live in Denmark, Bendigo and PindiPindi, a tiny town in North Queensland. I currently live on the Sunshine Coast with my husband, three children, a dog and a snake. I have a B.A. in Humanities and a Graduate Diploma in Education.
When did you know that you were a writer?
For me, being a writer has less to do with words on paper and more to do with paying attention. The wonderful children's writer Kate Di Camillo says on her website:It is the sacred duty of the writer to pay attention, to see the world
When did you first read your writing aloud or give it to someone to read and what was their reaction? How did it impact on you?
Sharing your work can be a daunting prospect for an aspiring writer but it is so important to get feedback from a trusted source. When I first picked up on the idea that I wanted to write I undertook two online courses followed by a three month mentorship with Nike Sulway. Nike'sresponses and feedback to my early work was always positive and constructive.There is no way I would have had the confidence to attempt a novel without it.
Did/do you have any writing heroes?
Anyone with the courage andtenacity to follow a writing project through to completion is a hero in my eyes.
What and when was your first acceptance? How did you feel?
My first acceptance was when I won the 2015 Emerging Queensland Writer — Manuscript Award. Part of the prizeincluded a contract with UQP. To say I was excited when I found out I had won this award would be an understatement.
What is your favourite genre to write? Why?
I didn't set out to write YA but I find myself loving it more and more.
How long have you been writing? And what have you written?
My very first steps to becoming a published author started in 2012. I have written two picture books, a handful of short stories and one and a half novels.
Of your own work – do you have a favourite? Why is it your favourite?
My favourite would have to beBecoming Aurora.I cannot articulate how wonderful it feels to actually complete a project as huge and daunting asa novel.
What is your favourite genre to read? Why?
I love picture books and fantasy novels, literary fiction and everything in between.
But, if pushed, I would have to say that Australian YA is a particular favourite of mine.
Do you have a favourite author?
That's a tough one! For children, I particularly love David Almond, Kate DiCamillo, Roald Dahl, E.B. White, Anna Fienberg, and heaps more!
Some excellent Australian YA writers to check out: Karen Foxlee, Claire Zorne, Margo Lanagan, Melina Marchetta, Marlee Jane Ward,Rebecca Lim and Nova Weetman.
Do you write full time?
It depends what you mean by full time. I help my husband run a home based business and run around after my three children. Somewhere in between, the writing happens.
Have you ever won an award/s or been shortlisted? What was it for?
Through the CYA competition I have placed second for Picture Books and first for YA.
Last year I was awarded Emerging Queensland Writer – Manuscript Award.
Do you participate in writing workshops as a student? Which ones were memorable?
The annual CYA Conference is always interesting and worthwhile. If you are an aspiring writer it is also a great place to network and make new friends.
I would also recommend The Novelists Boot Camp at the Queensland Writers Centre. This weekend course waspresented by the funny and informative Dr Kim Wilkins. If you are interested in learning how to plot and plan out your next novel, this is the course to take!
We all know that would be writers should read and write as much as possible – do you have any other advice?
Be patient, everything takes longer than you think.
Join or start your own critique group. Critique groups are a fantastic way to gain support, give and receive constructive feedback and share ideas. Learning how to critique is a fantastic skill that not onlyimproves your own writing/editing skills but is also a great way to help others.
How might people find you? Website, Blog, Facebook etc.
My webpage is: www.elizabethkasmer.com
Facebook — Elizabeth Kasmer

subset: commoncrawl


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Are you seeking to create a beautiful Fall wedding?
As a bride to-be, you have a lot of tasks to complete! Planning a wedding is incredibly time consuming, and there are so many different ways in which you can create your dream big day. The best tools a bride can have as she plans her wedding are quality sources of inspiration. Seeing how other weddings were developed is the best way to gather insight for your own big day.
Here at Rose Petal Events, we have had the honor to assist in planning many weddings. We enjoy sharing these weddings as a way to inspire other brides to-be.
If you are planning your own wedding day, and are in need of a little inspiration, you are in luck! We recently had the opportunity to plan a beautiful Fall wedding which took place at The Castaway Burbank. To discover all of the lovely details which were captured by Photography with Heart & Video, be sure to continue reading:
- The Ceremony. From the moment this wedding began, there was plenty to buzz about. The happy couple welcomed guests with a unique wedding guest book and a towering floral centerpiece to add the beauty of blooms, which were created by Van Nuys Flowers. The stage was set for the beautiful bride to make her way down the aisle. Rose petals lined the aisle, and the entry to every row of seats was adorned with a darling display of roses. The adorable ring bearer and flower girl lead the way to the altar. The bride then met her groom at a lush altar, overflowing with stunning greenery and blooms. They then joined each other in marriage, which a gorgeous display of true love!
- The Cake. With a lovely color palette of orange hues, blush and gold, the wedding cake, which was created by Jaqki's Cake Creations, certainly looked spectacular. The newlywed couple presented a four-tiered cake with differing textures and a rich display of their color palette. Better yet, the cake featured fresh blooming roses with a sprig of greenery. To top it all off, the couple featured a customized wedding cake topper to add a dash of personalization. The couple also chose to showcase scrumptious desserts in addition to the wedding cake, provided by Simply Cupcakes of Pasadena & Porto's Bakery & Cafe.
- The Reception. After such a romantic ceremony, the guests made their way to the reception. Each guest was greeted with a custom place card and another stunning display of blooms. Flowers weren't the only sight that greeted guests. A fabulous display of pumpkins and a custom-made sign as well as gorgeous lighting and monograms, created by Coastal Event Lighting and Productions - Michael Gardner. In addition, the couple provided some great entertainment with a festive DJ, Professional Disc Jockeys Inc., and even Lobsta Truck, for a midnight snack!
It was certainly an unforgettable Fall wedding, and we were so pleased to help plan it! The newlyweds were able to begin their marriage in a beautiful setting, and here at Rose Petal Events, as a wedding planner in Los Angeles, California, we were so honored to help create such a magical day for a beautiful couple. To begin working with your own Los Angeles wedding planner, please feel free to contact us today.


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Product Description
You will receive 6pc of porcelain beads
Handmade porcelain beads add color and zest to jewelry. These beads are great for countless design possibilities. They are smooth and warm and quiet when worn. Due to the handmade nature of the beads, size, shape and colors may vary slightly.
Quantity: 6
Material: Porcelain
Color: Green
Size: about 16.5mm in diameter, 6mm thick, hole: 1.5mm
US residents, for imported goods from Canada up to 200$ there are no duties or taxes.
Please note that colours may appear differently depending on your computer monitor.
The coin in the picture is the same size as a US quarter.
Thank you for looking, please contact me with any questions.
Jewelry supplies, glass beads, metal beads, lucite beads, beads, cabochon, headpins, hooks and all the findings you will need.
~ Subscribe to our newsletter: http://eepurl.com/i-whD
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~ Twitter: @Thebeadsofdreams
Je parle français alors n'hésitez pas si vous avez des questions.


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Crisis Interventionist
Job Description
Behavioral Health Technician
Crisis Interventionist
AZ-Kingman-Kingman Outpatient Clinic (O)
Southwest Behavioral & Health Services is a large and growing, non-profit community-based provider of behavioral health services with locations throughout the Phoenix metropolitan area, rural Maricopa County, Gila, Pinal, Mohave, Coconino, and Yavapai Counties. We are a well-established voice in the community with more than 115 sites, over one thousand employees, and 40 years' experience.
Join Southwest Behavioral & Health for exceptional growth opportunities driven by our promote-from-within philosophy. We provide an EXCELLENT compensation and benefits package, including immediate participation in our 403(b) program with 20% company match after 1 year of service. Generous Paid Time Off (PTO) includes 3 weeks of time-off your 1st year (available after 6 months) and increased vacation accruals after 2, 5 and 10 years of service! We offer low cost medical insurance and offer 100% company-paid dental, Short Term Disability, Long Term Disability, and Life coverage for employees. Other great benefits include 10 paid holidays, vision, licensure/certification reimbursement, tuition reimbursement, prescription drug discounts, chiropractic services, 100% paid Employee Assistance Program, and much more!
Kingman is looking for a crisis interventionist to join our Kingman outpatient team! This position will work Monday-Friday (40hrs) 3 weeks out 4. On the fourth week, employee to be on call only, for after hours and weekends.
In this position you will provide crisis intervention, screening, assessment, and treatment planning, to adults and/or children/adolescents. As an integral member of our interdisciplinary team you will develop and implement treatment or case plans, assessment criteria, and programmatic goals, objectives, and activities. Your primary role will be to respond to the crisis needs in the community and clinic setting for immediate assessment and/or de-escalation. Other duties include:
- Regular and ongoing assessments of individuals that present in crisis to the emergency room, clinical staff, law enforcement/first responders, and community or family members.
- Provide continuous 48 hour weekend crisis coverage.
- Coordinate or provide transportation when needed in order to ensure that clients are safe and have access to necessary services.
- Works closely with other agencies in order to maintain knowledge and process for completion of involuntary commitments.
- Works closely with law enforcement, hospital staff, and first responders in order to educate the community
- Attends and participates in in-service training sessions and related training opportunities as made available, as well as appropriate staff meetings.
- Documents client services provided according to the approved SBH clinical standards, rules, regulations, and procedures.
- Educates law enforcement, hospital staff, first responders, other providers, and stakeholders regarding SBH services and services available as requested. Provides consultation and education to community agencies, schools, and neighborhood groups.
- Coordinates closely with case managers, clinicians, and medical in order to ensure continuity of care.
- Assist clinicians and case managers in providing therapy, clinical case management, and outreach for families and/or individuals
- Performs intakes and psychosocial assessments of families and their individual members.
- Conducts home visits as needed and case consultations with other agencies and organizations.
- Maintains required number of client contact hours per week.
- Works with others professionals to plan, market and implement new programs.
- Minimum qualifications consist of 21 years of age, Master's Degree (Psychology, Counseling or Social Work), plus one year of full-time BH experience and Motor Vehicle clearance.
- Must have fingerprint clearance issued by the Arizona Department of Public Safety or be eligible to receive within eight (8) weeks of hire
Application Instructions
Please click on the link below to apply for this position. A new window will open and direct you to apply at our corporate careers page. We look forward to hearing from you!Apply Online
Posted: 8/15/2019
Job Reference #: 4822


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The Gianna stud earrings with princess cut sapphire is a delicate choice perfect for everyday wear. We love to pair this stud with larger earrings by placing it in the first or second ear piercing. A great choice to add a pop of color on your ear.
This piece is made to order, please allow 10-14 business days for is to ship!
- 14K yellow, white, or rose gold
- Diamonds, round brilliant, 0.20ct, G-H color, SI1 clarity
- Sapphire, 0.06c. princess cut, pink, blue or green
- Post backs
- Made in New York with the finest craftsmanship!


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Steps to make Welcome+To+Lolicit+Loli+And+Shota+Forums
Making an anime is not any simple activity. It's an entire procedure for building and illustrating a global, finding motivations, weaving tales – this is a significant undertaking! However, it's also a great exercise in imagination. If you're interested in anime you will most probably really enjoy making your own.
Method 1 : Outlining a global
Figure out where you want your history to be establish. Is it going to be on an alien entire world? Is it going to be on a location that is relatively very much like places on earth? You don't have to figure out everything about the whole world, nevertheless, you do need to figure out where you want your storyline to occur.
For example, maybe you want the major action of your history that occurs in a world where most people live in caves because beyond caves there are always a ton of dangerous slime pits that you could fall into.
Find the interesting reasons for having your world. Like slime pits! Animes frequently have parts of their world that are somewhat magical or peculiar in some way. Maybe pianos talk and present people lots of advice. Maybe there are flying beasts that individuals use to get from location to place. It generally does not need to be something extremely fantastical or something out of an science fiction book – just choose something that works with your world and your story.
For instance, the magic of the world is actually a simple folk tale that could or may well not be true. Maybe on the slime pit world there's a tale that if you fall into a slime pit and survive you will be granted special forces but no person has learned if this holds true or not.
Decide the technological advancement of this world. Will be the residents of your world surviving in apartment complexes or in real wood huts? Are they hunting for their food, or can they go out to evening meal are restaurants? Definitely there are a lot of other choices among and beyond these instances. The technological position of your world will inform a lot of the techniques your characters connect to the issues that face them.
For instance if someone comes into a slime pit in a scientific advanced world, maybe it's no big offer because everyone would wear anti-slime suits.
Method 2 : Creating Characters
Choose what they look like and their personalities. You should try to choose what they appear to be at the same time that you select their personalities. Try sketching the heroes and then jotting down beside them what their personality features would be. Perhaps you have one figure that is absolutely sensible and perceptive but susceptible to dropping their temper. Perhaps you have another character that is very loyal but very unkind to strangers. Sketch drafts of your individuals.
The way the character types look is important because it can play to their personality. For instance, maybe the muscular figure is the hero. Conversely, maybe the very muscular character is a complete coward. Either way, his body informs his personality in an interesting way.
Decide on a protagonist. You don't need to have just one main persona, but it's nice to provide the reader a person to root for. Most anime have a protagonist.
Consider giving them special ability. Anime often feature character types with special talents accomplishing incredible things. It might be a good idea to give your main character some kind of power that will assist her or him offer with whatever the challenge in your anime is going to be. Your character doesn't have to have the ability to fly or have ultra durability – find something small and interesting that helps the type deal with original challenges.
For example, maybe your persona is incredibly brave! That's a special capacity, but it isn't magic.
Create relationships between the characters. Family, love hobbies and friends of your protagonist should all play a major role in your report. They are the strongest contacts that individuals have with others plus they help motivate, motivate, and create issue. All of those things are positive qualities in a fun story.
Find out each characters inspiration. The other characters can play into your characters desire, but find a distinctive thing that drives them. It can be getting educated or getting the lady, it just has to be something that the protagonist is very interested in.
Method 3 : Beginning to Animate Your Anime
Start by sketching your world within an animation program. You'll find many free web animation programs online that allow you to easily create a world and figure. You've already made a decision what you want the world the appearance like, so now you merely need to take it to life. Invest some time and don't be anxious if it changes from your original plan.
Draw your personas. Make your personas in the same computer animation program. Refer to the drawings and sketches that you have already done to be able to inform your final product.
Draw your heroes interacting with the planet. Now all you need to do is incorporate the people and the earth. This will likely immediately begin to give you ideas for tales and potential story lines to follow. Maybe your individuals want to explore those significant cliffs out in the length that they have never gone to before. Maybe sunlight gets dimmer and dimmer each day plus they have to determine what is going on. The surroundings can be a huge impetus in virtually any history, and anime is not any different.
For example, maybe your world has huge slime pits everywhere. Maybe your main characters little sibling comes into one of the slime pits and the other character types have to determine a way to save him. Now you have the beginning of a plot!
Related posts to Welcome+To+Lolicit+Loli+And+Shota+Forums
Lolicit Loli And Shota Forums
Also known as "we re running out of disk space". We ve managed to hit a whopping GB of attachments on the forums, which is running pretty close to the total amount of space available to us. Me the rest of the staff will have to come up with a plan to free some space, most likely this will involve pruning old attachments..
Method 4 : Incorporating Plot and Dialogue
Combine dialogue that fits the drive and personalities of the individuals. Once you've characters and a global you can begin turning the personas interacting with the earth into a tale. This involves creating dialogue. Use dialogue that fits the situation and the character. Try to make the dialogue as genuine as possible. Think about the way you speak and create interactions like that. Interactions are seldom 100 % directed. They sway and change subject constantly. Figure out a way to add authenticity, and humor to your dialogue.
Make sure that you have a newbie, middle, and end. The beginning, midsection, and end does not have to be amazingly distinctive, but keeping this organization in mind will help you plan out your plot. Have a look at other classic literature and commence to figure out what the beginning middle and end of those stories are.
For instance, maybe the beginning of your anime gets the protagonist's little sibling slipping in a slime pit. The center could be when your protagonist deciding to travel alone in to the slime pit using an anti-slime suit to try to find his little brother. The end could be the thrilling conclusion where the slime demons living in the slime pit allow only 1 of the brothers to leave, as well as your protagonist continues behind so that his little brother can go back home.
Include a personality arc. Persona arcs don't need to be really simplistic and flat. Not every story has to begin with a miserable persona and end with a happy persona. Rather, a personality arc should allow the primary character to endure some sort of minor change or come to a realization. Even when that realization is the fact nothing improved from when the storyline began, that still contributes a dimensions to the story. What you don't want is your identity just running around doing assorted activities with no chain of reasoning.
For instance, maybe your protagonist is selfish at the start of the storyline but after aiding save his sibling he starts to realize that he really does care about other people but that he was shutting himself off to the entire world. Now you can treat why he was shutting himself off to the globe within the next episode.
Method 5 : Completing Your Anime
Think of a good name. The title is exactly what catches people's attention. Make sure the name has something regarding the plot.
Decide if you need your anime to be one report or a string. This may regulate how your storyline ends, or if it ends in any way. If you want your stories to be a series then you have to determine a way to keep people interested. If everyone is satisfied with the way the first story ended, then there is no reason for them to view your next occurrence. Create cliffhangers.
Add a thrilling climax and realization. This is a big part of fabricating a cliffhanger. If you're making multiple shows you want to balance the lines between concluding the prior episode and establishing the next tv show up. They shouldn't feel like they watched the first tv show for nothing, however the viewer should also be fired up to see what goes on next. Find this balance.
Link the knots in your history. If there is a love interest at the start of the storyplot, there must be some acknowledgement of this at the end of the storyline. Not everything must tie up properly, but you want your anime to look well planned and professional. When you have a bunch of untied account lines it seems messy.


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This time Warp car has only covered 18,000 miles since new. The first owner, an elderly gentleman, had the car for 40 years and only covered 11,500 miles. Finished in Graphite.....
Volvo 122 Amazon Rally car with
double carburetor - lock differential - advanced instruments - rally lamps - sports steering wheel - bucket seats - roll bar
Used for ice speed races in Sweden
The Volvo Amazon was first introduced to the public in 1956 and hit the roads in early 1957. It was ten years later that the 123 GT version was added to the series. It was the most luxurious an sporty.....
Price: € 18.900,-
New at Classic Park, this Volvo Amazon P1300. The car was produced in 1969 in Volvo's new plant in Gent (BE) and then delivered to its first owner in Norway. Why deliver.....
SOLD! find our current stock at - details above
Very reliable classic Volvo Amazon with powerful B18 engine. For consequent use and long trips the Volvo Amazon might be the perfect vintage car!.....
Very nice Volvo Amazon B18 from year 1961 in the rare black color.
The Volvo is in perfect condition and is well maintained.
Car came from Sweden to the Netherlands in April 2005 and has since.....
For sale Volvo Amazon 121 , original , used . The engine is working , the body and the interiors are to restore . This is a good base for a restoration project . The car is located in South Italy.....
1966 volvo amazon, 1800 twin carbs, 2 owners from new, good allround condition, all electrics work, so does the heater, original jack, also original service book,stamped from 1966 to 2000,engine rebuild,.....
Hi ,
I have ForSale my Red Volvo Amazon (D-Reg) 1966 121
B18 engine with Twin sus's fitted to it also a overdrive fully working I recently restored the car from the ground up and m.o.t.ed it.....
1966 Volvo 122S Amazon 4DR Sedan
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Mythbuster: Are Carbohydrates Really Bad For You?
Watch: https://youtu.be/XO92NAtxGNU
Let's discuss distinguishing between complex carbohydrates and simple carbohydrates. For example, there is a profound difference between 50g of sugar and 50g of oats. They both weigh the same, but how nutritionally dense they are and how they affect your body's metabolism is dramatically different.
Complex carbohydrates are chains of simple carbs strung together in long, complex chains. Complex carbs are better because (a) they contain vitamins, minerals, and fiber that are important to your health and (b) they generally do not have as dramatic of an influence on your blood sugar. Complex carbs are generally called starches and healthy sources include green vegetables, whole grains (oatmeal, pasta), starch-heavy vegetables (potatoes, sweet potatoes, corn), beans, lentils and peas.
In contrast, simple carbohydrates are simple carbs that are not strung together in long, complex chains. Examples include glucose, fructose, dextrose. The significance of this is (a) they do not contain the same vitamins, minerals, and fiber that you find in complex carbs and (b) they generally have more dramatic influence on your blood sugar. Examples would include sugars, syrups, jams, fruit drinks, soda and candy and these contain what are often termed refined carbs.. You may hear them referred to as FODMAPs, which stands for "Fermentable Oligo-, Di-, Mono-saccharides And Polyols."
The lack of nutritional content in refined carbs is somewhat obvious and I won't dive into an explanation. It goes without saying, the lack of vitamins, minerals and fibers in any food compared to an alternative is a bad thing.
On the other hand, the influence on blood sugar is significant and requires explanation. Simple carbs are more easily absorbed in the gut and readily available for use. In small amounts or during exercise, this is helpful, but in excess and over an extended period of time, this causes multiple metabolic problems. The first is that it will eventually become stored as fat, leading to weight gain. The second and perhaps more important, is that your cells develop resistance to insulin, a hormone responsible for getting sugar into the cells, as a result of being overly saturated with these simple carbs. The consequence of this is that you eventually can develop type 2 diabetes from this and all the issues related to that (kidney, eye and foot disease, among others)
So now that you understand the difference between simple and complex carbs, there are a few more important points to make.
The first is that carbs are one of three macronutrients, which also includes fat and protein. You need all 3 macronutrients for survival. Your body is smart and capable of converting fats and proteins to carbohydrates, namely glucose (sugar), but this is not an efficient use of resources. So in order to be metabolically efficient, you do need some carbohydrates at baseline.
The trick is (a) how many and (b) what type of carbs. In general, for the average person, 20% of your dietary intake should be carbs, and the other 80% should be a mix of fat and protein. This varies somewhat depending on your level of physical activity and any medical problems you may have.
20% of what you may be asking? 20% of your total daily calorie intake. According to the NIH, the average adult male needs 2,500 calories per day and the average female needs 2,000 calories per day. Again, this will fluctuate based on your height, weight, level of physical activity and goals. But this is a rough estimate. I would encourage you to look into total daily energy expenditure and a calorie counter if you want to know more.
The second thing you need to understand is the type of carbs you are consuming. There are simple carbs in some healthy foods such as certain vegetables, fruit and milk. These should be your source of simple carbs. If you're eating table sugar, brown sugar, corn syrup, honey, maple syrup, molasses, jams and jellies, fruit drinks, soft drinks like soda, candy, baked goods or chips you're doing it wrong. Remember, these are going to significantly increase your risk of gaining weight and developing diabetes. They also have virtually no vitamins, minerals or fiber.
Health sources of of carbs are complex carbs. These should come from green vegetables, Whole grains (oatmeal, pasta, and whole-grain breads), Starchy vegetables (potatoes, sweet potatoes, corn, and pumpkin), and Beans, lentils, and peas.
So in summary, to get back to the initial point, carbohydrates are not inherently bad. They are an important and efficient source of energy for our body and brain. Your goals with carbohydrates will be to not overindulge, i.e. do not consume them in excess. As discussed, limit your intake to 20% of your total daily calories and do not consume them and exclude other important foods. When choosing carbs, choose complex carbohydrates over simple, refined carbs for their nutritional value and because they are better for your body's metabolic profile.


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We Sometimes Dreamabout the Perfect Roof. Honest.
Since 1988, our family owned roofing business has been serving Grayslake, Libertyville, Mundelein, Vernon Hills, Lake Zurich and Wauconda.
We are a local company with a dedication not just to our business, but to the community itself. We guess that is why when we drive past a home or business where we have done a roof replacement or repair, that there is just a little bit more pride. We love what we do, and we like to make our friends and neighbors happy.
Advanced Roofing Technologies believes that your roof should be a work of A.R.T. We think that every roof our company replaces or repairs is beautiful. While we don't expect our customers to host parties on their new roof (that could get a little dangerous), we have no doubt your guests would be impressed.
To us, a new roof is sort of like a beautiful piece of hand-built furniture. The really great carpenters carefully finish even those surfaces you don't see. The same with an honest and trustworthy roofer. Advanced Roofing Technologies goes out of its way on a residential or commercial roof replacement or repair, to take the time to make sure your roof is perfect.
We are proud of our many endorsements, testimonials and satisfied customers. Advanced Roofing Technologies is a member of the BNI network. However, our greatest satisfaction is when one of our satisfied customers refers a new customer to us. It is far and away the highest form of flattery. We believe that what sets us apart is that we strive to be professional, friendly and honest.
As a family-owned and run company you have our guarantee that we treat each customer as if you were members of our family. And by the way, we like our family very much!


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Ethan Hawke puts Matters of Food Waste in Perspective #BAD11 #WorldFoodDay
By the end of this month I will have thrown away an unopened package of bacon, one-quarter pound of cheese, one-quarter pound of turkey breast, a half-full box of granola cereal, one and a half containers of cream cheese and one half bag of Cheerios in the trash. Don't even get me started on the banana pudding that my Grandmother made weeks ago that I still didn't finish eating.
These items are either old, past their expiration date or stale and questionable to consume after being stored for too long. Yet, I woke up this morning hungry and disappointed that all I had to eat for breakfast was a peanut butter and jelly sandwich because toast did not seem very filling. It is an absolutely wasteful habit that does not help the environment and seems quite ungrateful considering the shortage of nutritious food that people are facing here and abroad.
You know that movie scene in "Alive" where a group of rugby team players who survived a plane crash eat the flesh of dead passengers while stranded on cold mountains? If not, don't worry. I didn't watch it yet either but will, along with the Martin Sheen narrated documentary "Alive: 20 Years Later" as soon as Netflix or Blockbuster ships them my way.
It is not easy to imagine eating human flesh in any capacity. It is also probably not easy for the average person to imagine eating old, smelly, expired or stale food either because we don't have to do so. We can just get new food but an even better alternative is to buy only the amount of food that is needed and no more.
No matter how bad the food I listed earlier in this post seems to me, chances are that the people munching on their friends in "Alive" (which is based on a trued story) would prefer my stale Cheerios or old cheese over human flesh any day of the week if they had a choice. Today, more than 50 million household have insufficient food supply according to a NY Times article. The piece also mentions a study by the Department of Agriculture reporting that just one fifth of the food waste could feed 10 million people each year.
A singer named Michael Jackson once said that he's going to chance the world by starting with the man in the mirror. I'm taking note from Jackson and starting with the woman in the mirror on a quest to reduce food waste. Who dares to join me?
by the way....
How much food have YOU wasted this year?
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EF's mission is simple
Opening the world through education.
In the past five decades, our educational programs have helped people of all ages and nationalities become citizens of the world.
What we do
At EF, our work changes lives for the better – our products give confidence and freedom to people across the globe. This "for profit, for good" ethos is what motivates our teams to do better work every day and drives our business to grow year on year.
A career with EF combines the support and opportunity of a large organization with the spirit and energy of a small company. We look for thinkers and doers – creative, collaborative and motivated people who are excited by education, communication and travel.
Key Facts
612School and offices
3Average languages
spoken by employees
20Business Units
52,000 +Employees
2000 +Staff relocations
per year
What we're like
We transform dreams into international opportunities.
With 580 schools and offices in 52 countries, and language at the heart of our business, EF is a truly international company.
You'll see culture and diversity celebrated at all of our locations, and, with such a global reach, you'll have access to opportunities worldwide.
At EF, we have an entrepreneurial culture where new ideas are heard, creative risks are taken and ownership is encouraged.
Dare to make something happen and you'll find a supportive team behind you.
As the world leader in international education, we're paving new roads for learning – using technology, research and design. Here's just a few examples of how we're doing it:
EF publishes the world's largest ranking of English Proficiency Index by country and is hailed as the world's most comprehensive benchmark of English proficiency.
From animation and architecture to mobile apps and film – our creative teams examine design from every angle to ensure the perfect balance between form and function.
Our Learning Labs develop technology to create fundamentally better ways to learn.
EF Research Network
In collaboration with Harvard, Cambridge and Peking Universities, we're conducting ground-breaking research into the way language is learned.
Outreach and impact
At EF, you'll find philanthropy and a passion for education.
We're committed to making a positive contribution to the global community – from our support for good causes and social change, to our efforts to drive progress in the way people learn.
EF Global Classroom Foundation
Aiding disaster relief efforts around the world and improving education for underprivileged children.Visit website
Culturalcare Kids First Foundation
Assisting organizations that provide direct services to underprivileged children around the globe.
Mentor Foundation
Founding and supporting research and initiatives in drug prevention.Visit website
Hult Prize
EF Founder Bertil Hult funds this student movement for social change in partnership with the annual Clinton Global Initiative.
EF and the Olympic Games
We have been appointed a remarkable six times as an Official Supplier and Sponsor to the Olympic Games, including Seoul 1988, Beijing 2008, Sochi 2014, Rio 2016, PyeongChang 2018, and Tokyo 2020.
Currently we are training students, teachers, and the public across South Korea about Olympic and Paralympic sports, concepts, and values as well as raising the English level of Tokyo 2020 staff as they prepare for the Games ahead.
EF Pro Cycling
Our international team is racing around the globe on the UCI WorldTour and popular amateur races, exploring the world.
Our structure
We're one company, but we're organised into a number of divisions that focus on different areas of our business.
We're also associated with Hult International Business School, an independent, not-for-profit business school as well as an independent not-for-profit exchange program – EF Foundation – and an insurance company, Erika Insurance.
EF Language and Schools
- EF English Live
- EF Local English Language Centers
- EF Local English Language Centers for Kids
- EF International Language Campuses
- EF Corporate Solutions
- EF Academy – International Boarding Schools
- EF EdTech
EF Cultural Exchange
- EF High School Exchange Year
- Cultural Care Au Pair
EF Educational Travel
- EF Explore America
- EF Educational Tours
- EF College Study Tours
- EF Ultimate Break
- EF Go Ahead Tours
EF Real Estate Holdings
- EF Campus and School Properties
- EF Office Properties
- EF Hotel and Residential Properties
Associated organizations
- Hult International Business School, Graduate School
- Hult International Business School, Undergraduate School
- Hult International Business School, Ashridge Executive Education
What EF people say
The main thing EF has done to support my development is to allow me to try out my own ideas and provide me with the resources to realize them - creating a pretty special "learn by doing" environment.
Eric Van DeldenSales Manager
EF looks like a large multinational company from the outside but operates like a startup on the inside. Fast paced, constantly evolving, ambitious.
Greg KeeganCreative
There are less rules and structures than the places I worked in before. It's more entrepreneurial - meaning you are encouraged to break new grounds, develop your business ideas further.
Guan WangProject Manager
Decisions are taken fast. There is an urgency to change and to achieve new targets. If you come up with a great idea I believe it will simply be realised faster in EF than in most other companies.
Jacob TorenPresident, EF English First
A friend who works for EF told me that to work for EF is like doing an exchange, but as an adult.
Linda KarlssonManager, US Allocations
In a way you are first thrown in the pool and then you are asked whether you know how to swim! But it's a challenging and fun working environment.
Marc LayolaSales & Marketing
I joined EF because of the opportunity to work on strategy and implementation across multiple projects, whilst being super hands-on. It's all about 'getting things done'.
Sophie DaunaisDirector of Accommodation
Want to go places?
If traveling the world, paving your own way, and making an impact is the kind of career you want, you're the type of person we're looking for.
Recently graduated?
Accelerate your career alongside some of the best and brightest minds.


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About Fitness Evolved
canada Misoprostol
After nearly a decade in fitness and rehabilitation, it became clear to us that there was an opportunity to deliver significantly better results than the variety of training approaches currently employed. First, generic training programs not only don't work for many people, but are actually damaging to some. Even facilities who claim to offer customized programs often do not know how or do not take the time to do an accurate assessment of what the client actually needs. A custom program only makes sense if it is what you really need. Second, for some reason, almost the entire industry has been ignoring leading edge research that can dramatically improve results We have spent years rehabilitating "strains" and "overuse injuries" resulting from poorly designed, inappropriate "fitness programs." We knew there was a better way.
As a result, we made a major investment of both time and money to identify and work with world leaders in fitness, performance and rehabilitation. We formed close mentoring relationships with these people to maximize our effectiveness in helping you achieve your goals as fast as possible. We formed Fitness Evolved to bring our education, skill and dedication to you
Fitness Evolved is the only gym in the Bay Area to be aligned with the world-class, brain-based training system of Z Health and the business and fitness programming system of Results Fitness– recognized world wide for their cutting edge business model and unmatched program design for fat loss.
http://tangentcarcare.ca/services-pricing/passenger-vehicles We've created the most evolved training system available, allowing for instant feedback and results assuring an injury and pain free experience while providing on-going breakthroughs for you. We believe the foundation for any fitness endeavor is a solid, custom-designed fitness program that addresses each individual's needs and goals. We provide each of our members long-term programs for guaranteed success — road maps that take you from where you are to where you want to go. We use proven scientific principles to design programs that pinpoint each individual's desired effects and goals, streamlining the process and getting you better results faster.
Andy Clower, ATC received his Bachelor of Arts Degree in Athletic Training from Anderson University. He has been a Certified Athletic Trainer (ATC) since 2001. During his time at Anderson, he worked with collegiate and high school athletes of all sports. After graduation, he took a job as a main clinical assistant for Anderson's team orthopedic surgeon, and was also Head Athletic Trainer at a local high school.
Upon moving to the Bay Area, he switched his focus to rehab and functional training. He spent five years working at one of the Bay Area's top Physical Therapy clinics as Head Athletic Trainer.
He has an extensive knowledge of how the body functions and moves, and has worked with many patients and athletes of all levels to not only restore function, but to reach levels beyond their previous abilities. He is an expert in movement assessment and firmly believes that our bodies are amazing machines, well designed, and capable of doing tremendous things. His approach is detailed, and he works closely with each client, teaching them safe and efficient ways to use their bodies and ensuring carryover to daily life or athletics.
Through his experiences in training and rehab he developed a passion for helping clients reach new levels. Hundreds of hours of research, attending seminars, and working directly with some of the best trainers, coaches, and therapists in the world enabled him to create Fitness Evolved's ground-breaking training system. He is currently a Z-Health Master Trainer and Instructor, teaching students and trainers from around the world how to help themselves and their clients achieve unthinkable results and change their lives.
He has become determined to change the standards of the fitness industry. Our mission is to change the way fitness is done around the world.
Jesse received his B.A. in English from U.C. Berkeley. He is a Z-Health Level 4 R, I, S and T-Phase Certified Coach and certified NASM (National Academy of Sports Medicine) personal trainer. He has also completed Z-Health's 9S: Structure, and 9S: Strength and Suppleness certifications for advanced neuro and strength training. Jesse's sports related experience includes 2 World Championships and 1 National Championship in Ultimate Frisbee, road racing bicycles, and competing in triathlons up to the half-ironman distance. He currently plays pick up basketball as his main exercise.
Jesse enjoys helping clients with all types of health and fitness goals, especially getting them out of pain so they can live more active, comfortable, and unlimited lives. This interest is heavily shaped by his personal experience using movement and Z-Health to recover from chronic and stubborn pain.
He grew up in Berkeley, graduated from Berkeley High and U.C. Berkeley, and has two teenage sons.
Catherine Chenoweth-Smith received her Bachelor's of Arts in Neuroscience from Oberlin College in Oberlin, OH. She has a lifelong love of learning, people, dance, and circus skills. Having taught dance and object manipulation to all ages as well as studying anatomy and physiology in college she is in a unique position to appreciate the work done at Fitness Evolved. It is truly inspiring to see so much change effected every day.
After working as a teacher, dancer, circus organizer and instructor, outdoor educator, and in various offices she is delighted to join the team at Fitness Evolved. Catherine is excited to get to know you. She has completed the foundation Z-Health courses (R, I, S, and T Phase).
Regan Wareham graduated from Ball State University with a Bachelor's degree in Exercise Science. He was fortunate enough durning his education to observe elite level trainer's that use a neurological lens when working with clients. This lens, shaped by Z-Health is not an unfamiliar to Regan as he has taken R, I, S and 9S Structure.
Regan is an ambitious trainer who loves working with people and walking away from a client knowing that he in some way made a positive impact on that person's day – whether it was getting them to feel the target area in a mobility drill, or with encouraging words through a tough workout. Regan feels more excited than ever to officially be part of the team. He is looking forward to a wonderful, empowering future here at Fitness Evolved!


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Cheap travel insurance isn't hard to find online, but be wary of suppliers who reduce costs by cutting out meaningful benefits. At Worldcare, our objective is to provide you with the best priced insurance, whilst maintaining the highest standard in travel insurance cover. We don't need to heavily discount our policies because we get the price right in the first place – no gimmicks to get you to quote and then add some policy extras later, our comprehensive policy covers your medical, cancellation and luggage cover needs, plus so much more.
When spending those precious holiday dollars, it may never seem cheap - travel insurance is an invisible product after all, but you need to make sure that when you really need the benefit, you have the best level of cover available to you. Compare Worldcare's Comprehensive cover and you'll see we've considered all your travel cover needs.
Worldcare travel insurance is issued and managed by AWP Services New Zealand Limited trading as Allianz Partners and underwritten by Allianz Australia Insurance Limited ABN 15 000 122 850 (Incorporated in Australia) trading as Allianz New Zealand. You should consider the Policy Wording before making any decisions about this travel insurance policy.
For further information on Allianz Australia Insurance Limited's financial strength rating, please refer to the following Financial Strength Rating and Overseas Policy Holder Preference Disclosure Notice found at https://www.worldcare.co.nz/.
Allianz Partners website |
Terms and Conditions
Privacy Policy.


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So pleased to say this is out on 21st September…
There are several updates to my schedule page.
Site update
Happy Easter!
One or two updates for you all.
Yeomen of the Guard
Schedule Update
Some more dates added to my schedule…….roll up, roll up 🙂
Schedule Update
Greetings! Several new dates now added to my schedule.
Schedule Update
A couple of new late dates this June..please come along if you can!


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Exciting Event Tonight! As part of ICF Coaching Month, MARCIA WIEDER, America's Dream Coach, is being interviewed on KtC Radio!
I am deeply honored, and very excited to have Marcia Wieder, America's Dream Coach, and founder of Dream University, appearing as a guest on KtC Radio this evening at 6.30pm EST! Marcia is well known for her speaking, coaching, seminars, and as an author – she has even been a guest on Oprah's show!
Join us as we celebrate ICF Coaching Month, and talk about what is happening in the world of coaching.
Marcia will also share her wisdom and experiences, and talk about her new movie Beyond The Secret. Come armed with questions, which you are welcome to email to me ahead of time at firstname.lastname@example.com To participate in the chat room during the show, make you register with Blogtalkradio first. (Very easy! 😉
If you aren't able to make the show live, feel free to access the archived podcast which will be available at the same link!
http://www.blogtalkradio.com/KeystoClarity-coach (cut and paste into browser)
Make the show a favorite to get email reminders of upcoming shows!
Go to www.keystoclarity.com to subscribe to upcoming events and Louise's Newsletter!
Look forward to 'seeing' you on the air!!
Coach Louise


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About Our Teamthose that make it all happen
Matt Barnard
Director, Partner, Entrepreneur, Tour Guide, Water man, Musician
Matt lives and breathes the outdoors. He has represented NZ for white water rafting and loves to surf in his spare time. He has lot's of tourism experience and is very passionate about conservation. Matt is also a Musician and if you ask him nicely he might just sing you a song.
- Tour Guide 75%
- Director 50%
- Relationships and Managment 50%
Nev Wilson
Director, Partner, Entrepreneur, Tour Guide, Water man, Engineer
Nev is a water sports Guru! From white water kayaking to surfing this man know's it like the back of his hand.Nev joined the crew to create the perfect work/life balance to spend more time with his young family. Nev is passionate about giving you nothing but the best experience.
- Tour Guide 25%
- Director 50%
- Relationships and Management 50%
If your going to do something, do it well. We strive to create the best within ourselves and others.
It is experiences that we remember, experiences that bring us together and experiences that shape us but we all need a friend to share those experiences with. We know how to have fun together and we foster a culture of friendliness in what we do.
We genuinely want you to have a great time and we genuinely want you to enjoy our amazingly lakes, learn their story and be impacted by their natural beauty. We value humility.
To remain safe, where possible, you must avoid doing unsafe acts that could otherwise be carried out safely. We foster a culture of safety within all that we do.
Don't Be Shy. Get In Touch.
If you are interested in working together, send us an inquiry and we will get back to you as soon as we can!


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Nextinnos Support
Email Support :email@example.com
Tele Support :+914714014698
United Kingdom
Email Support :email@example.com
Tele Support :+44 7846 402604
Quick Quote/Live demo Click Here!
Live Support
Quick Contact
Sales : email@example.com
HR : email@example.com
General : firstname.lastname@example.com
We are just a clik away!
We are moving ahead to the fourth year
Our timeline..
2015 Jan 01
We commenced our operations. Initially started as a hub of innovations, technology and creativity. We offered Web, branding and promotional services.
2015 Feb
Started a creative brand, DreamsLiveMedia for creative services like Animation explainer videos, Graphic designing, VFX, etc.
2015 Jun
We started our operations in UK.
2016 Jan
We incubated inside ICFOSS, Technopark, Trivandrum.
2017 Feb
Moved to own space inside Technopark Campus, Trivandrum, India.
2017 Nov
Started office and operations in UK.
2018 June
For future growth and better establishment, we rebranded ourself to Nextinnos Technologies Pvt. Ltd. with development center in India and presence in UK, Australia, Japan and Middle East.


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Peter Loukianoff was a co-founder of Almaz I. He led Almaz investments in nScaled and Qik (acquired by Skype).
Prior to establishing Almaz, he was a partner at Alloy Ventures from 2001-2008. Before joining Alloy, he was on the founding teams of Autonomy, Inc. (US), a pioneer in Internet search, and Ubiquinet, Inc., a location-based services and software company.
He earned an MBA and BS Engineering from the University of California, Berkeley.


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This post may contain compensated links. Please read our disclaimer for additional information.
I love train travel and it is always my preferred method of transportation for many reasons.
The ability to sit back, relax and enjoy the scenery in a comfortable seat in a railway carriage has got to be the best way to travel.
I have been on some of the great rail journeys around the world although still have quite a few on my bucket list. I also love sleeper trains though admit they are not always the most comfortable method of travelling.
This list of top 10 amazing train journeys around the world includes some of the most luxurious trains but are also scenic shorter trips that can be more affordable for most travellers.
Here are the my first 5 choices for the best 10 railway journeys around the world?
To take a trip on the Ghan is at the top of my bucket list. This epic journey across Australia takes you 2979 kms from coast to coast (Adelaide to Darwin and vice versa) and across the red centre of this amazing continent. There are a number of options to take on Southern Railway's Ghan train service including the epic Ghan Expedition which takes 4 days and 3 nights to cross the continent. Imagine that? Well yes I can and I cannot wait to take this train.
The Ghan's symbol is the camel and its name comes from the epic camel riders who blazed a trail into the red centre of Australia over 150 years ago.
To find out more about The Ghan check out their website – I look forward to the day when I can write up my experience of taking this epic train.
Mention beautiful train journeys and countries that spring to mind always include Switzerland. For good reason – the scenery in this beautiful Alpine country is breathtaking. I have taken many train journeys in Switzerland and have quite a few favourites including catching the train from Geneva to Zurich (Lake Geneva is gorgeous), the cog railway up Mt Pilatus and taking the train from Zurich to Milan.
However famous train journeys include the Glacier Express, the train journey to the Top of Europe and of course the Bernina Express.
A few years ago I took the Bernina Express from Tirano in northern Italy to Chur in Switzerland with my niece. The journey takes about 4 hours and is one trip where sitting back sipping a glass of prosecco whilst passing through some of the most beautiful scenery in the world is a must.
To find out more about the Bernina Express and other panoramic rail trips available in Switzerland read my post all about our experience as well as the Rhaetian Railway website!
Why not include a trip on the Bernina Express into your Europe train trip itinerary?
There are many different routes to choose from with this luxury train company based in South Africa. One of their routes runs 1,600 km from Pretoria to Cape Town and this is the route I have chosen for this list (though their 15 day Cape Town to Dar es Salaam route is a close second!)
Stops along the route Pretoria to Cape town include a visit to Kimberly where you can peer into the Big Hole and visit the Diamond Museum! If you are in Cape Town read my insider's guide for the best things to do and see when you are there.
Check out the Rovos Rail site to book this amazing experience.
Another classic journey is the Eastern and Oriental Express train service which runs between Bangkok and Singapore. Crossing from Thailand through Malaysia before finally entering Singapore (or vice versa) this trip is synonymous with luxury where the train itself is as much a part of the experience as the journey!
Stop off at the River Kwai and also in Georgetown Penang on the trip of a lifetime. Read more about this trip here!
FLåM RAILWAY TO MYRDAL – NORWAY
I make no secret of my love for Norway! One trip that should be on any train lover's bucket list is the stunning journey between Flåm and Myrdal.
Make sure to experience the beautiful boat journey from Gudvangen to Flam along the magnificent Sognefjord and Aurlandsfjord before catching the train from Flåm up to Myrdal. The return train journey takes about 2 hours and you will see magnificent waterfalls, mountains and the fjord landscapes on your trip.
To find out more about the Flamsbana check out their website.
For my 5th choice in my top 10 railway journeys around the world I have chosen the Caledonian Sleeper. We took this sleeper service a few years ago but since then the stock has been updated and therefore this journey remains high on my re-do list.
The Caledonian Sleeper offers a number of routes from England to Scotland ending in Aberdeen, Inverness or Fort William on the Highland route or Glasgow or Edinburgh on the Lowland route. (And vice versa obviously!)
We wanted to go to Fort William but unfortunately the line had been damaged following a massive storm so we travelled from Euston to Inverness but what a trip it was! Waking up to stunning Scottish scenery will be an abiding memory. If Fort William is your destination depart Euston at 9:15 pm and arrive in Fort William at 9:55 the following morning.
First Class (your own room and single bed), Standard Class sleeper room with twin beds (we took this) and a standard sleeper seat are options on this service.
Check out the Caledonian Sleeper website here!
Those are my first 5 choices of top 10 railway journeys around the world! Have you traveled on any of these services? Do you have a favourite that is not on my list? Maybe it made it onto my final 5 choices – CLICK HERE to find out which train trips I picked for the final 5!
Author: Tracy
Over the last 50 years I have lived and worked in 7 countries on 4 continents and travelled to many more. I enjoy exploring and learning about new places and meeting people on my travels. History, reading, photography, nature and wildlife are my interests and I am ALWAYS researching and planning my next trip (preferably by train)
With a lifetime of travel experience, and a network of friends all over the world, I share genuine insider guides, recommended best book lists and train journey inspiration to help YOU travel authentically to some of the most beautiful places on earth.
Come and join me as I travel the world one country (and train journey) at a time!
This post may contain compensated links. Please read our disclaimer for additional information.


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Latin America and the Caribbean Capacity Development Project
In 2006, the UNCTAD TrainForTrade Programme and the Latin American Integration Association (ALADI) signed a Memorandum of Understanding to secure collaboration on a capacity development project in Latin America and the Caribbean. The Latin American and Caribbean Economic System (SELA) joined the cooperation in 2008 and provided new dynamics to the implementation of the activities in the region.
The project aims to further develop and strengthen human resources and institutional capacities involved in international commerce, trade related services and investment in Latin America and the Caribbean. This is done by implementing different training courses and activities, by supporting institutional frameworks for trade related issues at national and international level, and by promoting trade and investment policies for a dynamic, equitable and sustainable development.
Over 1200 participants have been trained through the organisation and dissemination of the following courses and seminars in the region:
- Legal Aspects of Electronic Commerce
- Regional Workshop on Cyber Legislation
- Training of Trainers Workshop – Modern Port Management
- Technical Tutor Training for Distance Learning
- Negotiators of International Investment Agreements
Several technical assistance missions have been carried out in the following areas: Sustainable Tourism, Port Development, Investment and Trade -Development.
Training and development activities
The TrainForTrade Programme organises distance learning courses, face-to-face training courses and regional workshops. Training material is constantly updated and adapted to the requirements of countries and organisations.
The participants are from governmental institutions and private sector (professional associations, chambers of commerce, consumer centres, training centres, etc.), and are responsible for decision making and policy formulation related to trade, development and investment.
Technical assistance activities
The project carries out assistance and support for the identifying of needs for capacity building, policy development, the establishment of networks for sharing knowledge and information, and the dissemination and publication of research and reports, etc.
Study on Prospects for Latin America in Harmonizing Cyber-legislationn (UNCTAD/DTL/STICT/2009/1):
Study on Prospects for Harmonizing Cyberlegislation in Central America and the Caribbean (UNCTAD/DTL/STICT/2009/3):
Budget and financial contribution
The Ministry of Industry, Tourism and Trade (MITC) and the Ministry of Foreign Affairs and Cooperation of Spain are financing the above-mentioned activities, except for the Port Training Component, which is financed by the contribution of the Port Authorities of Gijon and Valencia.
The total contribution from 2006 to December 2011 amounts to USD 1,050,000. Countries in the region also provide in-kind contributions to the development of activities.
Beneficiary countries


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21 February 2014
Bascomb, Neal. The Nazi Hunters: How a Team of Spies and Survivors Captured the World's Most Notorious Nazi. Arthur A. Levine Books, 2013.
This book details the search for and arrest of Adolf Eichmann, the man who was responsible for creating the Nazi's "final solution" and sending millions to extermination camps. The narrative follows Eichmann as he escapes to Argentina under an assumed name and as Mossad officers form a team, capture him, and bring him to justice.
I enjoy reading about WWII, but I was not as interested in the details about chasing down Eichmann. I don't remember hearing anything about him in history class, so it may have been different if I had grown up knowing him as one of the big names of WWII. But this book has lots of good details and includes photographs of Eichmann as well as the men who eventually caught him, and I believe this book would be very popular among teens who enjoy reading about WWII.
Recommended for: teens, adults
Red Flags: brief discussion of the Holocaust
Overall Rating: 4/5 stars
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I was invited to spend a half-day in Borders General Hospital where I had the opportunity to see much of the excellent work staff are doing for patients.
I attended patient safety meetings, visited a number of wards and got to chat to senior members of staff, as well as doctors and nurses. It was a very informative visit and I was struck by how much good work is being done to improve patient flow and reduce what is called "bed blocking".
This is an ongoing problem across the NHS and NHS Borders is already doing better than most to ensure patients are receiving treatment in the right location, but staff want to improve things further.
Any time a patient is left in a hospital bed when they are ready to go to a different ward, to the community or to be cared for at home is a waste of resources – and it isn't in the patient's best interest either.
The problem is that often getting the ongoing care arranged is difficult and sometimes out-with the control of clinicians. Nevertheless, staff are doing all they can to ensure that within the hospital things are run as smoothly as possible and that they work with GPs and care providers to move patients on, when appropriate.
I also had a frank discussion about issues you might have read about in this paper recently, such as the ongoing review of clinical services, the issues NHS Borders have had around cancelled operations and how the health board is dealing with patient complaints.
I am always impressed with the level of commitment all staff show for patient safety and improving patient care. Any comments I make about our health service are never a criticism of doctors, nurses or other healthcare professionals who do a fantastic job.
But I realise their already difficult jobs are being made any harder by the Scottish Government which is failing to invest in our health service in the Borders and has failed to reform our NHS.
I also asked if I could see the Margaret Kerr Unit, the new palliative care facility opened in 2013.
By the grace of God, I have not had to visit a relative here, but I had heard so much about it from patients and families who are impressed with the level of care provided.
The whole of the Borders got behind the fundraising effort to build the unit and it is a fantastic facility, providing a peaceful and supportive environment for patients and their families in difficult times. It is designed with patients' dignity and care in mind and staffed by some of the most hard-working and highly-skilled clinicians around.
My weekly surgeries throughout my constituency of Ettrick, Roxburgh and Berwickshire take place on Wednesday mornings.
I will be in Jedburgh and Kelso on Wednesday, October 28. More details and further dates can be found on my website – www.johnlamont.org.
No appointment is necessary, so please feel free to come along if you have a problem which you think that I might be able to help with. Alternatively, please call my constituency office on 01450 375 948 and I will do my best to assist.
For tours of the Scottish Parliament, please contact my parliamentary office on 0131 348 6533.


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Out of all the places we've visited, I still think this is one of my favorite places: Istanbul, Turkey. I love the beauty of the water with the city in the backdrop. The mixtures of sounds and smells from the water, street food, boats, and traffic make it very fun place to just sit and take it all in. There is a lot to see and do--you could never do it in one or even two trips. If you ever get a chance, go and visit this place. You'll not be disappointed!
The last week was very busy for me with a conference and visiting friends, so I got a little behind in my photo of the day's and portrait project. I resolved within myself when I started these projects that I wouldn't be obsessive about it, so I am just going to pick up where I left off! :) I have some very fun photos to post soon though--some portraits from people I've randomly met and some new places for me that I've never been to. It's fun visiting new places! Have a great day!


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inkl. MwSt. zzgl. Versandkosten
The newly developed Ass Savers Extended has been designed specifically for the needs of roadies. Road cyclists, the pro peloton (Lotto-Belisol, Belkin), continental teams, and development teams have all adopted and used Ass Saverss in recent years for training and racing (most notably in Milan-San Remo, 2013/2014). It adds 30mm (1.2 in) of length over the Ass Savers Original in order to reduce more road spray, especially at high speeds. The new Ass Savers Extended utilizes the same patent pending attachment system as the Ass Savers Original and Ass Savers Wide. That means it snaps into place on the saddle?s front rails in seconds and requires no tools. It also fits almost all saddles with standard rails, including carbon rails. Please note: Ass Savers Extended does not fold to store under the saddle. Specification: ? Compatible with just about every rail saddle ? Easier to attach ? More stable once in position ? Easier to detach ? More resilient to wear and tear


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Join me at Allison Sprock Fine Art this morning May 21th from 10:30am to 12:30 for coffee and treats. Georgia artist Yasharel will be at the gallery joined by gallery favorites Marcy Gregg and Cher Cosper.
Cher Cosper
Marcy Gregg
You know I love a good giveaway, so now is your chance to enter a drawing to win a $100 gift card toward any painting. First time at the gallery, there is a whole other drawing just for you!
Hope to see you soon!!


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A landlord with an insufficient insurance policy has been left out of pocket by £100,000, an event insurers say shows the importance of checking policy amounts.
The incident involved a fire at a block of flats started by accident when a tenant cleaned car parts in a kitchen using petrol. That led the insurer to make a claim of almost £400,000 only to discover his cover level was insufficient and had been so for many years.
Total Landlord Insurance, which settled the claim, warned landlords to double-check their Landlords insurance policies: firstly to check they've kept up to date with increasing property values, and secondly to make sure they've had a professional valuation on the worst case scenario of a total property rebuild.
Getting the cover level right isn't just a case of preparing for the worst. Landlords who make smaller claims that are well below their cover level might not get the full amount if the property is underinsured: most insurers reserve the right to reduce payouts proportionally in these situations.
Insurers also warned that although meeting electrical safety checks is vital to mitigate risk, more than a third of claims result largely or solely from tenant behavior such as kitchen fires, smoking or burning candles.
Home Insurance News Feed
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Hello Everyone!!! Hope you had a wonderful week. I worked pretty hard this week at my "real" job. Not much time for scrapping lately. However, I did finish up this sweet layout using the wonderful Scraps of Darkness February kit "Our Story". I chose this week to feature my sweet grandson Cameron asleep on his Daddy's chest. I just love these sweet, quiet moments, which with this little guy are very few LOLO!
The kit is intermingled with the gorgeous Blue Fern Studies (BFS) "Memoires" and Prima "Love Clippings" collections. I chose the BFS paper for the background and inked and stamped it using the Bella Clear Stamp (Main Kit) and added a little gesso splatters. I matted my photo with various papers from both collections and tucked in some journaling notecards included in the Main Kit. I also fussy cut the little embellishment that runs down the vertical strip on the left side of the photo that comes in the Prima notecards (Main Kit).
I had the adorable heart chipboard from my stash that I painted with the Art Alchemy acrylic paint "Metallique Royal Red" that came in a previous kit. It gives a really nice shine. Perfect for the chipboard!!
On the left side of the photo at the bottom I created a sweet flower cluster which has a little bird image that I fussy cut from one of the BFS papers "Calling Cards" in the center. I used the flowers from Prima "Vintage Emporium" collection which are included in the Floral Add On. I also added some Finnebar Art Stones around the cluster and in other areas of the layout that came in a previous kit.
On the top right side I added a fussy cut butterfly from a VERY old Scraps of Elegance kit, and tucked in a little flower from a previous kit.
The little title was fussy cut from one of the Prima 6x6 "Love Clippings" paper pad that comes in the Creativity Add On. I used another phrase at the top of the photo from the same paper.
I hope you enjoyed my layout and how I created it. It was so much fun, as it always is using the Scraps of Darkness monthly kits. I encourage you to consider joining us. You cannot believe all the fabulous goodies that come with the kit and all of the Add Ons that help you to create your own "Love Story".
Till next time.......


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The 'Casual Gown' Is a Totally Thing
Is it possible for a gown to feel casual? This lavender baby from Tobi certainly does - it would be equally at home at a summer wedding or a rooftop cocktail party alike. It's soft, pleated and extra flowy - cue the dramatic twirling. I loved the soft purple one, especially for Spring/Summer, but it's also available in dove gray and slate. And, call me cray-cray but I think I may try to work a sweater over this and rock it as a maxi skirt during colder months.
I recently booked an Airbnb in Boston, a penthouse apartment with gorgeous views of the harbor and an amazing rooftop, so I got to test-drive the dress al fresco with wine for two before heading out to dinner.


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1. Leslie Jones is the biggest star the show has had in the last few years. She has the most **sparkle** since Will Ferrell.
2. Kyle Mooney's sense of humor is the most "millennial," and was played up a lot last year. He's also a surprisingly good character actor.
3. The show was playing a lot with absurdism in 2016, possibly to cater to millennials raised on Tim & Eric, but has now returned to satire, cuz Trump.
4. Overall, the show has been a lot better in the last year, relying less on repeated skits and taking more chances.
5. Monologues that involve half the cast are corny. I wish they would push more celebrities to do a mini-standup routine. Kristen Stewart was doing surprisingly well and then the cast members joined her and it went south.
6. Related: My favorite hosts are usually standup comedians (Louis C.K., Aziz Ansari, Dave Chappelle).
7. Larry David was a surprisingly awesome character actor when he was on last year. His Kevin Roberts "Can a bitch get a donut?" skit was so funny it made me wish they had cast him way back in the day. But my favorite skit in recent memory was this bizarre Michael Keaton ad agency skit.
8. The show underuses Bobby Moynihan, and overuses Cecily Strong.
9. I see why they've made Weekend Update so long—they are trying to compete with The Daily Show, et. al. That said, comparing it to those shows makes it seem extra bad. Colin Jost and Michael Che just aren't funny or charismatic enough to compete with Stephen Colbert, John Stewart, Trevor Noah, Samantha Bee or John Oliver.
10. Letting cast members like Pete Davidson do standup during Weekend Update does help us get to know them, but it feels out of context and odd. I want more Drunk Uncle, but also less repeat characters I don't think are that compelling. I'm difficult.
11. Cast members who just left the show hosting it the next season is obnoxious. That's way too soon for a victory lap.
12. Related: The Kristin Wiig/ Bill Hayder era was the most obsessed with repeating skits and inside jokes. That said, I do enjoy them as post-SNL actors, outside of SNL. Can they stop returning to host for awhile?
13. This season of SNL has been the best in a long time, thanks to Alec Baldwin and Melissa McCarthy, and also our president giving them endless amounts of material. Playing Putin will cement Beck Bennett's place on the show for a long time.
14. New cast member Mikey Day is super funny, although he seems to be used in place of Kyle Mooney now, which is sad.
15. There's a lot of cast turnover lately, which makes it hard to get attached to new members. That said, I prefer that to keeping mediocre people on the show for years. New cast members bring new POVs and styles of comedy to the show, which it needs to stay relevant.


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The day after 9/11, I sat stunned and disbelieving by my fish pond. The air so dense with grief it was difficult to breathe yet the fish and birds seemed oblivious to my lamentations. A blue jay swooped in and chased a cardinal away despite the fact that the feeder was full. It reminded me of the senseless destruction of the World Trade Towers. God created a universe full of abundance yet his creatures were destroying each other in greed and violence.
Someone asked, "Where is your God now, Dr. Burns?"
Here is my answer.
9/12/01 10:47am Psalm Twenty-three Revisited or Where was God?
The Lord is my shepherd as a man holds a box cutter
I shall not want and a woman phones her husband.
He maketh me to lie down as a jet crashes in green pastures.
He leadeth me beside the fiery gates of steel and the still waters.
He restoreth my soul as a priest administers the last rites
He leadeth me in the paths of righteousness to a fireman.
They die in each other's arms for his name's sake.
Yea, though I walk by two hundred and twenty crumbling stories
through the valley of the shadow
a cardinal sings of death.
And a blue jay chases the red one away,
I will fear, he is hungrier,
no evil. He is bigger.
Thy rod and thy staff, they comfort as a cardinal sings on me.
Water circles a pond as thou preparest a table
where one hundred fish swim before me in the presence
and this flowing creates the breath of my enemies.
As fish breath under water and my cup runneth over.
Once there were three fish, he annointeth my head with oil,
Now there are one hundred.
Surely goodness and mercy will follow
Fish swim, fish breathe and a cardinal sings to me, all the days of my life.
And I will dwell, now the thousands search in the house of the Lord
for loved ones to say goodbye, I'll miss you forever.
Julia W. Burns, MD


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Property Details
JACK'S Lake, Arnstein, Ontario
Sales Representative
RE/MAX North Country Realty Inc., Brokerage* - Port Loring
Tel: (705) 757-1421
$128,900 - For Sale
Are you looking for a location to enjoy the many beautiful lakes, excellent snowmobile trails and popular hunting areas that Northern Ontario has to offer? Well, look no further! This '6.9' acre property is situated on Jack's Lake, part of a five lake-chain, offering approximately 8 kilometres of boating, fishing and exploration. Enjoy privacy and '706' feet of water frontage! The property is accessed by water; parking is available at the public boat launch. Easily install a dock and clear part of the property to build your dream cottage, or pitch a tent and enjoy the surrounding nature. Don't be surprised by passing deer, and an abundance of nature and wildlife at your feet. The Port Loring and surrounding area is home to a large population of White-Tailed Deer, Moose and many other types of wildlife. OFSC snowmobile trails are close by. Wildlife Management Unit #47. Don't forget to ask about the details and advantages of building/owning in an Un-Organized Township.
- Property Address:JACK'S Lake, Arnstein, Ontario
- Property Type:Vacant Land
- Lot Size:Irregular shape
- Acreage:6.9510 / 3.0 - 5.0 Acres
- Sewage Type:None
- Water Type:None
- Waterfront:Jack's Lake
Sales Representative
RE/MAX North Country Realty Inc., Brokerage* - Port Loring
Tel: (705) 757-1421


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Engineering internships are a core part of any professional engineer's career. The field of engineering is extremely diverse, and there are many different types of internships available. For the purposes of this article, we'll be focusing on entry level engineering internships for engineering students.
Engineering internships are usually defined by specialty. At entry level, you need to search for internships which are directly relevant to your career goals and academic qualifications requirements.
You can also search for internships related to your intended career path to improve your portfolio of skill sets. For example, if you're an electrical engineer, you may be able to do internships of electrical systems or power systems, et cetera.
Engineering internships should be viewed as extremely useful career assets, whether you're a generalist or a specialist. They are also a very good way of upgrading your skills to meet new market and employer demands. Moreover, it's worth visiting our site where you may get additional information about internship graphic design or internship web design.
Searching for an engineering internship
Engineering internship search basics:
- When doing a search for engineering internships, do not use generic terms. There are so many types of engineering and so many advertisements, that you need to focus on specific search terms. A combination of search terms like "electrical systems internship" will narrow down your search very effectively.
- Use reputable corporate entry level engineering internship programs as a basis for comparison with other internships. The top of the range internships are good benchmarks for training content and quality. Internships which are deficient in areas of training won't be as useful for employment purposes.
- You can use professional advice as a very good source of information regarding internships. Professional engineers are always happy to help, and they can usually provide you with more useful information in a few minutes than other people can provide a lifetime.
- Create a list of internship choices, based on your preferences. It's a good idea to contact internship providers directly, if at all possible. The providers can give you all the information you need about your application, and useful insights into specific requirements.
Applying for engineering internships
- Make absolutely sure when you make your application that you have fully addressed all candidacy requirements. This is absolutely critical. Internship applications, like job applications, are often computer-screened, and leaving out required information must be avoided at all costs.
- Don't guess about application requirements. If you're not sure about specific requirements for an internship, ask the provider. They'll be able to give you all the guidance you need, and straighten out any unclear points for you.
Engineering scholarships and internships
Many engineering scholarships also include internships as part of their basic curriculum. These scholarships are particularly useful for those who may otherwise find themselves floundering around looking for internships in their particular discipline. An internship for mechanical engineering students, for example, will be part of the scholarship package.
These scholarships are available throughout the United States, and it's well worth your while to investigate your options. You'll also find that local colleges can direct you to scholarship opportunities and give you useful advice.


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11 Comments
John Simonetti
We share a lot of the same philosophies.We tried to work together years ago. But nothing came of it. Maybe it's time to reconnect. We both have extensive years in the automotive advertising business and have a relentless drive to be the best at what we do. Maybe there's a bigger calling. Maybe we should explore the possibilities of some how teaming up? What do you think?
Open Your Jaws and Howl
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Always Be Closing
[…] say that 1 in every 23 people is a salesperson. If every salesperson only made three mistakes a year that would result in 136 million mistakes a […]
Small But Big
[…] I tend to fail when I try. So now my life experiences have taught me to just try and make small changes. They have much more of a chance of actually happening. We all face the same dilemma. Our energy […]
Putting Lipstick On A Pig
[…] truth is, we are human and sometimes greed, pride, laziness, fear, or ineptitude gets in the way of the goal and where we should be. We believe that we can get there […]
[…] Decide now. […]
Gumballs Cost A Quarter
[…] Leave a Comment Too many people in the automotive industry get stuck trying to find that elusive sales idea as if it's the holy grail and the solution to all their problems. They feel someone has the idea […]
Being Different or Creating Difference?
[…] something pretty common in our industry, and probably in most industries, and that is we constantly strive to be different from or to outdo our […]
ADS Direct Mail Marketing Success Potion
[…] "employees." So different from "personnel." So different from "marketing professional." Talent! Just saying the word makes you pull up your chin and puff out your chest. It makes you feel good […]
Opportunity Doesn't Knock
[…] Opportunity is everywhere, but you won't hear it knocking at your door. Today opportunity hollers behind the closed doors of fear, confusion, and business as usual. What I've learned for sure in the automotive direct mail marketing business is that the future belongs to those unwilling to accept the stifling status quo, to those who are not afraid of new ideas, who stay focused, puzzled, excited, and execute those ideas. These are the geniuses. […]


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Xiaomi Mi Home Gateway explained
Firstly, we need to have installed the Xiaomi Mi Home app. In addition, we need to install a gateway to control all our other devices easily. So in this article, I will try to get the Xiaomi Mi Home Gateway explained.
The Gateway functions as a central hub to connect devices. Let's look at what this gateway does and why you would need one. This small unit has a ring of multicolored LED lights and a built-in speaker. Both serving various functions, there's a small button on top of the device. The Gateway can be plugged in directly into a wall socket.
It works as a nightlight or it could play internet radio.
But this gateway also functions as a central hub for all these wireless sensors and switches in the Mi home ecosystem.
The gateway connects to your router over Wi-Fi, and it connects with all these sensors.
Xiaomi Mi Home Gateway can pair up to 30 devices and control them.
Many automation rules can be set up as "local rules". This means these rules will still run even when the internet is down.
The Xiaomi Gateway can be added to the Xiaomi Mi Home app, with a simple "add device" task.
After you have installed it to the Mi Home app. You will see the Gateway device page. This page will have 4 tabs.
In the Home view of the gateway's device page, you will see an overview of the connected devices to that gateway.
In the Control Panel row, you can find quick toggles to turn on or off some connected devices.
Another tab is the Gateway Auto tab, where you will find all the common automation functions of the gateway.
In the Devices tab, you will find a list of all the connected devices to this gateway. While in the bottom, you can find a button to pair new subdevices with the gateway.
While with only one gateway you can control all devices in your home. Therefore My advice, depending on the space of your house, is to get one 10 meters far away from the router. Also add another one 10 meters away from the first gateway. While this will be a perfect solution to not overcrowd only one gateway.
Xiaomi Mi Home Gateway explained
In conclusion, I hope this article helped you know a little better what you can do with a Xiaomi Mi Home Gateway. Finally, a Xiaomi Gateway is the Heart of a smart home.
Finally, here you can follow all price history for the Xiaomi Mi Home Gateway and buy it at a small price and with big discount.
Price History for Original Xiaomi Mi Smart WiFi Remote Control Multi-functional Gateway Upgrade
|Current Price
|Highest Price
|Lowest Price
Last price changes
- All prices mentioned above are in United States dollar.
- This product is available in Gearbest, AliExpress.
- At gearbest.com you can purchase Original Xiaomi Mi Smart WiFi Remote Control Multi-functional Gateway Upgrade for only $11.99, which is 59% less than the cost in AliExpress ($29.50).
- The lowest price of new Version Original Xiaomi Mijia Gateway Multifunctional Gateway Alarm System Control Mi Door Sensor Bell Temperature was obtained on 25/08/2019 15:31.
Article based on this video by Xiaomify


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Am J Physiol Lung Cell Mol Physiol. 2016 Apr 8:ajplung.00220.2015. doi: 10.1152/ajplung.00220.2015. [Epub ahead of print]
Increased Lethality and Defective Pulmonary Clearance of Streptococcus Pneumoniae in Microsomal Prostaglandin E Synthase-1 Knockout Mice.
Dolan JM1, Weinberg JB2, O'Brien E2, Abashian A1, Procario MC3, Aronoff DM4, Crofford LJ4, Peters-Golden M5, Ward L1, Mancuso P6.
The production of prostaglandin E2(PGE2) increases dramatically during pneumococcal pneumonia, and this lipid mediator impairs alveolar macrophage (AM)-mediated innate immune responses. Microsomal prostaglandin E synthase-1 (mPGES-1) is a key enzyme involved in the synthesis of PGE2and its expression is enhanced during bacterial infections. Genetic deletion of mPGES-1 in mice results in diminished PGE2production and elevated levels of other prostaglandins following infection. Since PGE2plays an important immunoregulatory role during bacterial pneumonia we assessed the impact of mPGES-1 deletion in the host defense against pneumococcal pneumonia in vivo and in AMs in vitro. Wild type and mPGES-1 KO mice were challenged with S. pneumoniae via the intratracheal route. Compared with WT animals, we observed reduced survival and increased lung and spleen bacterial burdens in mPGES-1 KO mice 24 and 48 h following S. pneumoniae infection. While we found modest differences between WT and mPGES-1 KO mice in pulmonary cytokines, AMs from mPGES-1 KO mice exhibited defective killing of ingested bacteria in vitro that was associated with diminished inducible nitric oxide synthase expression and reduced nitric oxide (NO) synthesis. Treatment of AMs from mPGES-1 KO mice with an NO donor restored bacterial killing in vitro. These results suggest that mPGES-1 plays a critical role in bacterial pneumonia and genetic ablation of this enzyme results in diminished pulmonary host defense in vivo and in vitro. These results suggest that specific inhibition of PGE2synthesis by targeting mPGES-1 may weaken host defense against bacterial infections.
Copyright © 2015, American Journal of Physiology - Lung Cellular and Molecular Physiology.
bacterial pneumonia; host defense; lung; prostaglandins; streptococcus pneumoniae
PMID: 27059285 [PubMed - as supplied by publisher]


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Wednesday, May 3rd: 6pm to 8pm
Thursday, May 4th to Saturday, May 6th: 10am to 6pm
Saturday, May, 6th: 10am to 1pm
Saturday, May, 6th: 4pm to 7pm
(BD30 for 1 workshop or BD50 for both, payable in advance to Words)
Now accepting Anime/ Manga/ Comic Illustration submissions for an art show at More Words! Deadline to enter is Wednesday, April 26th by 12 midnight!
We are interested in artworks inspired by Undertale, FNAF, Pokemon, Attack on Titan, RWBY, Vocaloids, various anime, video games and any other fandoms. Crossover art is also welcome. All Mediums accepted: oil, acrylic, inks, pens, crayon, charcoal, chalk. Mixed media also accepted. Two dimensional ORIGINAL art will be accepted. Each artist may submit to three entries.
There will be also be two workshops run by graphic novelist Anna Thackray, author of The Awakening of Shamal.
Saturday, May, 6th, 10am to 1pm: Design Your Own Character - this will be an introductory course using "Manga Studio"
Saturday, May, 6th, 4pm to 7pm: Create Your Own Character - students will learn how to create their original characters - using their own choice of medium: clay or through drawing.
(BD30 for 1 workshop or BD50 for both, payable in advance to Words)
For all questions and submissions contact Christy Burton at firstname.lastname@example.com or WhatsApp at 32299793
All are welcome!