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Sizzling Colt for Riverina
This stunning colt was the highest priced lot at the recent Magic Millions 2017 Gold Coast March Yearling Sale.
Sold by Riverina customer, Gleeson Thoroughbred Connections, the colt was fed on Riverina FEED & BREED PELLETS. Congratulations Wally, Jill and team. We look forward to being involved with more cracking yearlings like this one!

subset: commoncrawl


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Sunday, July 22, 2007
TV Knitting MarathonsPosted by Virtuous at 7/22/2007
I believe I officially O.D. on blogging the other week. :op I blogged 6 out of the 7 days and didn't feel like posting much after that! Haha!
Also, let me just say Traveling Teddy was very popular on my blog! LOL He was a big hit! :oD
If you want Traveling Teddy to come visit you, there is now a nice website link that Anna set up on "How to Get Traveling Teddy" to come visit you!
The knitting world has decided to take him over! :oD Haha! So click on the link and sign up!
By the way, Teddy has safely made it to Alabama and you can continue to track his travels by clicking on the link above as well. So thanks everyone for commenting on his farewell! :o)
In other blog worthy news, mid-last week I finally received THIS!
YAH!!!! I am a die hard fan of the Golden Girls (GG)! WHOA!
I waited patiently for all the seasons to come out on DVD, because I just knew they were going to bundle them all up in one package. And I got it! E.bay is a wonderful shopping center! :op
So GG has been playing over here non-stop. It is the BEST knitting T.V. ever!!! :oD
Aside from my #1 choice S.ex and the City (SATC) as my TV knitting marathon. :op YAH!
Now let me just say I also have all of the SATC seasons (unfortunately not the bundle pack - I couldn't wait back then!) and I LOVE those too!! (Not to mention I also own the SATC complete episode guide book :op)
I had grown tired of running my SATC DVDs to the status of "hot" and decided to give them a rest by changing things up a bit with GG!
Have y'all noticed the similar parallels of GG and SATC?
I realized why I was head over heels for both of them so much!
BOTH - are 4 women who are friends
BOTH - have the theme of living single and of course "s.ex" in them :op
BOTH - sit around at a table to recognize and discuss the ups & downs of life
BOTH - have the "crack up & laugh out loud" trigger :oD
BOTH - ran for at least 6 seasons! (GG at 7)
Of course one group is young in their flirty 30s and the other group are over their nifty 50s.
I really like both of these shows because these are women who evolve to be close knit like family thru the experiences and journey of life - the good and the bad. That is what attaches me to them!
I really enjoy both of these T.V. shows because I can have a good ole time knitting along with them! Before I know it 2 hours has slipped by and I have made lots of progress on my knitting! So there is progress to show soon :op
So tell me! What can you just sit down and "go-to-town" as your TV Knitting Marathons?
Labels: Randomness
9 Comments:
- anna said...July 22, 2007 at 12:12 PMLOL, it looks like Traveling Teddy was lovin' Charlotte! Can't wait to see all the fun he has at Adrienne's place!
I know a lot of folks that LOOOVEEE them some Golden Girls and Sex in the City. For whatever reason, I could never get into either one of 'em. I am; however, a HUGE fan of Girlfriends off of UPN. Due to me working hours, I missed a whole lot of the season this past year, might buy some of 'em off of iTunes to knit to.
Aside from Girlfriends, I'd have to say that reality shows like the Real World are my favorite to knit along to!!!
- KimT said...July 22, 2007 at 10:09 PMi tivo knitty gritty and uncommon threads, general hospital and all my children. I think i can sit and knit to just about anything!
- Channon said...July 22, 2007 at 11:47 PMCurrent TV? Not much, but my stepson got me hooked on Charmed a couple of summers ago!
- Adrienne said...July 23, 2007 at 7:19 AMI can knit to almost anything.....but yesterday it was My life on the D List!!! LOL
- Anonymous said...July 23, 2007 at 10:04 AMStar Trek or Twilight Zone (I'm such a friggin' nerd, LOL).
- Stacey said...July 23, 2007 at 10:32 AMI keep TiVoing SATC even after seeing each episode probably 50 times. Hubby thinks I'm crazy....
- Sheila said...July 23, 2007 at 11:10 AMGG is definitely funny especially Mama Duke. I never got into SATC.. but my daughter is a fan. As for my favorite show almost anything on Life Time.
- Robin said...July 23, 2007 at 12:18 PMI never thought about the comparisons between SATC and GG, but now that you mention it!! I had a great time catching up on ER from the beginning - I knitted and did the treadmill all the way from the beginning through now, on DVD. Netflix is great for marathons like this. I am a reality TV girl for the most part though, and loved Project Runway (of course), America's Next Top Model, etc. They need new seasons for both of those!
- Ms. Lee said...July 25, 2007 at 3:40 PMI just popped in to say hi. But I love Golden Girls! My sis always teases me and says my shoes look like Blanche Devereaux's! LMAO! My sis don't know a damn thing about nothing!


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Triple Threat Foilayage - Sunday, June 30th, Spokane, WA (50% deposit per person)
Triple Threat Foilayage - Sunday, June 30th, Spokane, WA (50% deposit per person)
Advanced haircolor class designed to teach the art of blending classic hair painting with foil work. This class demonstrates how to create pops of extra brightness inside traditional soft lift balayage, with a combination of Open Air Balayage, "Baby Lights" (fine foil highlighting), Foilayage (balayage "V" or "W" placements inside a foil). The result of blending open air balayage with sections previously processed inside of a foil creates multi-dimensional lift in one process. Base breaking and shadow toning are incorporated to create perfect transitions and graduation of color.
Salon Capello
23505 E Appleway Ave #105, Liberty Lake, WA 99019
9:30am -6pm
Doll head, doll head tripod stand, balayage paddle, tint brush, weaving comb,10-15 clips, a couple color bowls, pre-cut foils (regular and extra long), blow dryer, brush, and notebook, pen/pencil


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Deeper Learning
In a previous post, we discussed what it means to be less student-centered and, instead, to hold the teacher, the student, and the subject in proper balance. This week, we're going to dive deeper into the student side of this triangle.
As a refresher, you can read the full post here, but this is what we said about the student side:
What does it look like when the student node is in proper balance?The student is in an environment that affords them a level of ownership over their learning, as well as opportunity to apply their knowledge, and develop intra- and inter-personal skills.
It turns out that what we are describing here is essentially the components of Deeper Learning.
Whoa, that sounds good. What is Deeper Learning?
If you've never heard of Deeper Learning (or at least never heard of it as a specific, formal concept), you can probably take a guess at its meaning. It sounds pretty good, right? I definitely want my students to learn concepts deeply — I'm not too thrilled about them learning things superficially and then just forgetting it all!
Deeper Learning, as defined by the National Research Council Panel in 2012, is:
"…the process through which an individual becomes capable of taking what was learned in one situation and applying it to new situations."
Ok, that makes sense. If you really learn something deeply, you should be able to apply that learning in a variety of situations.
It also turns out that there are some specific strategies for promoting Deep Learning. However, many of these strategies aren't easy to implement overnight. In some cases, they will require changes in curriculum and school culture. That's a lot to cover in one blog post and a lot for you to take on at the end of the school year.
Practical Takeaways
Since you can't just snap your fingers and achieve Deeper Learning, here are three key practical takeaways to remember in your own classroom:
- Communication and Collaboration
Learning to communicate ideas and work with peers is an important component of deeper learning. You can promote these skills with group projects, and assessments wherein students have to show and defend their work, like a portfolio review.
You can also support these skills by creating a classroom environment that feels very personal. When students feel connected to one another and feel a sense of trust, they will more easily develop these skills.
- Critical Thinking
Being able to think critically and figure things out is an important component of deeper learning as well. You can help promote this by giving students space to approach a problem and figure it out, letting them teach learned concepts to someone else, or giving students bigger, longer-term projects to tackle.
- Reflection
Finally, students are more easily able to transfer knowledge from one situation to another when they are aware of their own learning process. Try providing students the opportunity to reflect on their own learning or give them a chance to set their own goals and persist in reaching them.
As we continue to advocate for learning environments that honor the teacher, the student, and the subject in equal measure, these deeper learning takeaways help maintain the balance.
To learn more about the NRC's findings and read the full study written by American Institutes for Research and funded by the William and Flora Hewlett Foundation, go here.


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Ethereum's Geth Client Finds Vulnerability Less Than Two Days Before Fork
The hard fork software on ethereum's most popular client Geth has been retracted due to a denial-of-service (DoS) attack vulnerability.
Ethereum's Byzantium hard fork is expected to happen in less than two days.
On finding the bug, ethereum developers pushed a new software release, but data from blockchain analytics site Ether Nodes shows a relatively low rate – only 1.9 percent of Geth nodes – of adoption.
With Geth responsible for about 75 percent of ethereum nodes, this could mean a large portion of the ethereum blockchain will be vulnerable to DoS attacks after the hard fork.
Explained by ethereum developer Casey Detrio on Reddit, the vulnerability stems from an oversight in one of the new Byzantium features. The risk is that this vulnerability could be exploited by a malicious agent fixed on taking down ethereum nodes – the kind of attack to which ethereum is well familiar.
Both Parity and Geth faults are being discovered via some last minute "fuzz testing" – a thorough testing process that can reveal even the tiniest weaknesses in code.
Hard forks are hard
The surprises unearthed by the tests have been of unexpected severity, leading ethereum developers to question their approach to the hard fork release process.
Internal discussions are also underway about the possibility of postponing Byzantium, but this also causes issues. Doing that would require all nodes update their software with a later block time, and there's no assuring this can happen with such little time before the fork.
In spite of these concerns, the Parity developer team tweeted that the fork should be delayed.
Speaking to CoinDesk, Detrio explained that "updating is not necessarily a quick and easy process for users with extensive infrastructure," such as exchanges or mining pools, and requires ample time to be done correctly.
He added:
"The second concern is that there may be more undiscovered consensus bugs that could be found after the activation block, which would then result in needing to perform emergency client updates."
This article was first published by Rachel Rose O'Leary at Coindesk


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{PatronTotalPoints} PTS
Whether he's a foodie, fun-loving, loves to be pampered or likes to relax, there's something for every Dad at Crown Melbourne. Explore our top Father's Day ideas or shop online at Crown Gifts and let him design his own Crown experience.
Enjoy a two course bottomless lunch this weekend at Merrywell Bar and Dining between 12 and 3pm. Available every Saturday & Sunday. T&Cs apply.


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Raspberry-Peach-Mango Smoothie Bowl
This healthy smoothie recipe is a gateway to the smoothie-bowl craze. Use whatever fruit, nuts and seeds you like best to make it your own. Be sure to use frozen fruit in Step 1 to yield a creamy, frosty base for the toppings. Download a Free Quick Breakfast Cookbook!


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My gorgeous boy having cuddles after a feed…
The other reason it's taken me so long to get round to a post is because I've been having major trouble with my phone and computer…..I upgraded the software on my phone and now it won't let me transfer pictures to the computer…all the settings have changed and after getting so frustrated trying to sort it out the other day I was ready to throw both computer and phone out the window, so I stayed off both for a while with the exception of instagram…..I'm seriously thinking I'll have to take my phone into the telstra shop and ask them to fix it…..sometimes technology really sucks….
Lots of cuddles to be had….
And the other reason I've been a little lax in getting a post done is I just want to spend as much time with my new baby boy as possible…..he's so amazing to watch and he's just started smiling this week…and it's all these little things I don't want to miss because I'm on the computer….Things this time round are very different….I find I'm more relaxed looking after bub, I'm enjoying it more and while I'm totally engrossed in watching Francis get bigger and loving smooching him at every opportunity I get (pretty much all day hehe)….I have to admit I'm looking forward to him getting bigger so I can teach him things like gardening, refurbishing furniture, painting, swimming and basically showing him there's a lot more to life than t.v and computer games…..I want him to be an out door kid who loves being active and uses his imagination and inquisitiveness to enjoy different activities. Already Francis is very alert to what's going on around him, very, very strong in his neck and tries to climb up you when having a cuddle…..I have a feeling he's going to do everything early like his big sister Lauren did….
So yes while I'm still finding time to blog and report on life I'm enjoying all that's happening at the moment and looking forward to more to come…..well I'm off for now but I will be back soon so take care and Au revoir….xo


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Cigna CI, +1.08% provided a 2003 earnings forecast, excluding investment results, that was well below consensus analyst expectations. The employee-benefits company expects to earn $6.25 to $6.50 for the year, below the average analyst estimate as compiled by Thomson First Call of $8.84. Late Thursday, the company had slashed its third-quarter and full-year earnings outlook for 2002. The stock is currently halted for news dissemination. It last traded down $26.79, or 42 percent, at $36.81.
Cigna's 2003 earns to fall well short of expectations
Quote References
+1.74 +1.08%


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In Stock
The 'Ernesto' bag is a small elegant tote which can be used as a tote or as a cross-body bag using the fine textured material strap. It has gold accessories, a luggage tag bag bearing our brand's name and a gold hardware styling our bag.
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The Neeses | Family Session, Santa Rosa
Let me tell you a little something about this family. I have known Jill, the beautiful mama, since I was in 7th grade. I remember playing volleyball with her for 6 years! I also remember when she started dating Clay and when they became pregnant with Lexi. I hold such a special place in my heart for this family. I have seen them grow over the past many years and I feel grateful that they picked me to photograph their family for them. They really are a family full of love and laughs.


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If your disability claim is set for a hearing before the Social Security judge, it's a good idea to prepare for the types of questions that you will be asked. Here are the categories of questions that the administrative law judge may ask you.
If your case is based on a physical condition, you will be asked:
- The amount of time that you can sit without having to take a break?
- The amount of time you can stand without having to take a break?
- How long you can sit throughout the day?
- The number of breaks that you would have to take throughout the day?
- How much can you lift and what can you lift?
- How many times you can lift the object?
- Your activities of daily living including you ability to dress and bathe yourself?
- Can you do your own grocery shopping?
- What kind of tasks can you perform around the house?
- You may also hear a question that asks you to do a sedentary job, like if you were required to sit or stand at a table and put pencils in a box?
- Why couldn't you perform that job or task?
The benefit of preparing for these types of questions is that you are not thrown for a loop when you hear them from the judge. If you have any questions about a Social Security disability claim, you could always give me a call.


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Tuesday, April 27, 2010
21 comments:
How on earth did you get them to retain their shape without staining the peel or having to carve off lots of excess?ReplyDeleteReplies
Leave the limes in half....fill....and then cut into wedgesDelete
beautiful! you guys are so impressive.ReplyDelete
Cool idea! They would make such great party treats!ReplyDelete
simple way to produce these fyi. cut lime in half and remove the inside of the lime. fill the lime up and then slice after the jello has set.ReplyDelete
I want actual recipes, please!ReplyDelete
- AnonymousJanuary 10, 2012 at 8:02 PM
Question: How do you get the jello to maintain it's form in the lime when it's liquid?ReplyDelete
Cut the limes in half, and hollow out the insides. place them cup side up, so you fill up each half of a lime, and you'll cut them into wedges after they are set.ReplyDelete
Wow! So cute! I feel sweet now.ReplyDelete
Thanks for the recipe.
Rumah Dijual
- AmandaJuly 11, 2012 at 7:46 AM
Does anyone know how many limes To a package of jello?ReplyDelete
Sure! No problem! You've got a great blog and I've added it to my favorites for any time I'm looking for a new jello shot recipe!ReplyDelete
How much jello did you use?ReplyDelete
Wowww so nice..ReplyDelete
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The Internet is transforming the way we exchange value and ownership, manage risk and perform transactions. While this transformation is taking place across all segments of the industry, the security and safeguarding for ownership of assets and data is becoming increasingly important. In today's environment, cybersecurity is a priority at board level.
ZEBIOMETRICS, enabling technologies that deliver a better and more secure identification experience.
ZEBIOMETRICS, with its Swiss roots, whose mission is to spearhead the development of biometric interaction that facilitates the convenience and integrity of the individual. Enabling the highest level of biometric security – quite simply, by leveraging decades of human identification processes.
PoB® (Proof of Body) is a disruptive multi-layer biometric authentication technology that consists of identification mechanisms combined with a unique encryption algorithm that enables your physical body to become your most secure digital wallet.
We aim at securing the new disruptive class of human identification processes. PoB® allows government and commercial enterprises to establish trust that someone is who they claim to be. With its strong core team, unique technology platform and emerging global partnerships, ZEBIOMETRICS is well-positioned to immediately impact the biometrics market, being the only player in the market to provide such technologies.
PoB® (Proof of Body), Cold and Hot Wallet based on Body Biometrics for the Blockchain Era.
By combining the power of the Blockchain and several layers of biometric scans we have created what is the most deliberate evolution of personal identification.
The "Proof of Body" comes before your ID. Your ID is only a piece of the puzzle. Since we all have different ID's but only one physical body. Without any ID (i.e. Passport, National ID Card, Driver License) citizens will be able to prove whom they are by simply going through a simple and non-intrusive scan of their biometric assets.
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The benefits of the biometric PoB® solution include:
Strong Security:
The biometric data is part of your body and matched with a proprietary algorithm in certified devices to ensure that a person's data and privacy are protected. Since biometric data is unique to each individual, the combination of multiple biometric data is significantly increasing the security of the individual´s biometrical assets and aligned data.
Alternative to conventional ID:
A simple authentication using your Biometric assets can be performed directly on a certified device, offering an alternative to old fashion and insecure identification assets like Passports and National ID Cards.
Your body acting has your cold & hot Wallet:
Hardware wallets and USB drives are subject to loss, damage or being stolen. Do not to entrust any longer third-party services to secure your accounts. PoB® provides an excellent solution for those who require a high level of account security. Particularly for large or sensitive accounts, implementing a PoB® and PoP® cold storage Wallet is one way to eradicate the risk of unauthorised access and maximise personal privacy.
Combining PoB® cold & hot storage with additional layers of security, such as device encryption, can further contribute to creating a well-protected cryptocurrency reserve.


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Changes to Transfers (2-Hour Passes) & All-Day Passes Issued On-Board Buses
Tue Apr 04, 2017
Starting in May 2017, fare boxes onboard CTtransit local, express, and CTfastrak buses will issue Transfers (2-Hour Passes) and All-Day passes using bar-code reading technology rather than magnetically encoded stripe technology.
The bar code is printed on the front of the pass. Scan the bar code on the window with the red light on the fare box—a tone will sound indicating acceptance.
Free transfers issued on local buses are valid for unlimited rides on local CTtransit buses, going in any direction, for two hours from time issued, until printed time and date of expiration. All-Day passes must be purchased at the time the fare is paid upon boarding.


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For Google Adsense (GA) publisher, Page Level Ads is the latest ads features. Google has introduced this ads type in 2018. This ads make it easier for you to set up the ads code without any hassle. Before there is an Auto Ads menu on the Adsense dashboard there is a special Page Level Ads menu appear on the Smartphone (Mobile phone). And this time, iweblogsite will teach you How to Set Your New Page Level Ads Through Auto Ads. Please read below.
More visitor has habit to visiting your site using their smartphone. Therefore, you need to set up Mobile Ads that appear below or above the Phone screen. The ads are floating even though we're reading the article. Additionally when one of the other articles clicks will show a full ad of a Mobile screen with a Close Ad button
Also read : Add Link Adsense Unit for 5 Rows 2 Coloums in Your Blog
There are some experts who advise to enable Auto Adsense Ads to increase income. But in my opinion, sometimes posts in articles become messy. If you set up the ads manually more neatly and we can place the expected position in every position we want.
Here are some Ads include Auto Ads, Responsive Text ]Display Ads, In feed AdS, In-article Ads Ads, Matched Content, Anchor Ads (mobile only) and Vignette ads (mobile only).
So, How to Set Up Your New Page Level Ads?
Log in to your Adsense Account and Go to your Adsense Dashboard
Select My Ads and Auto Ads (Before taking the Ad Code you must choose any Ad Type that appears)
Choose Ads type that you want. My suggestion is better to select the bottom two ads are anchor and vignette. In addition it is better to install manually (text and display, in feed, in article and matched content ads)
Save and to get the Ad Code. please go back and look in the top right corner (Prepare Automatic Ads). Click and get the code
Set up the Ads Code, go to your Blogger Dashboard, Theme option, Edit HTML, CTRL + F, type
and then paste the code under the
code. Finally, Save theme.
You have successfully installed the latest auto advertisement. If you want to check the ads, open your blog through the smartphone browser.
Also read : How To Get Matched Content Ads and Myth About it
That's all about How to Set up Your New Page Level Ads Through Auto Ads (Google Adsense). Hope this article help your problem to set up adsense code. If you have most traffic from smartphone, than it will useful for you. Please share it if you think helpfull. Thanks for visit.


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Thursday, July 2, 2015
Understanding the Separation of Powers
Many ordinary folks, and sometimes even lawyers and political theorists, find the idea of the separation of powers confusing. People tend to be unsure what it actually entails – and those that know what it means can wonder why on earth we would want it.
This blogpost aims to offer a plain language explanation of the separation of powers and its attractions.
(Readers interested in learning more will find more detailed exploration of these themes in: Breakey, H. (2014). Dividing to conquer: Employing the separation of powers to structure institutional inter-relations. Research in Ethical Issues in Organizations, 12, 29-58. Special offer!! During July 2015, courtesy of this article being a winner in Emerald's 'Outstanding Author Contribution in the 2015 Emerald Literati Network Awards for Excellence', the article's full-text can be downloaded free.)
Many readers would be familiar with a simplistic notion of the separation of powers, sometimes called a 'tripartite' separation because it divides the institution of government into three distinct institutions based on their separate functions. On this footing, the separation of powers equates to a constitutional principle saying that: (a) different institutions peopled by different personnel, (b) should perform the separate tasks of government, and that there are, (c) three such tasks: rule making, rule judging, and rule enforcing (in technical terms: legislating, judging and executing).
Some writers trace this tripartite principle to Montesquieu's (1748/1989) The Spirit of the Laws, and Montesquieu was certainly one of the first political theorists to consider the reasons why dividing a system of government along these lines might carry surprising benefits. But in Montesquieu's work the principle turned out to be anything but simple. In fact, I doubt anyone attributing such a notion to Montesquieu has never even opened his insightful but complex work, riddled as it is with historical curiosities and delighting in happenstance political arrangements that produce unexpectedly good results. Whatever one might say about Montesquieu's thought, it is anything but simple. (My copy of The Spirit of the Laws runs to a lazy 722 pages!)
On this tripartite principle, a good political system aims to have a legislature (e.g., parliament) to create laws, an executive to police those laws, and a judiciary to judge them. The system will also make sure that each institution keeps to its own devices – the executive and the judiciary aren't allowed to dabble in law-making, and the parliament leaves the business of judging laws to the judiciary, and so on.
This notion of the separation of powers suffers from several problems. Perhaps the most obvious worry is that tripartite system, as described above, has never actually existed. All effective political systems actually possess myriad inter-connections between their institutions, allowing each institution to 'interfere' in certain ways with the other bodies' workings.
Consider the notion of 'checks and balances'. Checks and balances involve one institution being able, under certain conditions, to block or resist another institution's activities. Such checks effectively scramble the very divisions created by (and apparently recommended by) the tripartite separation of powers. To allow the executive to veto legislation, or to allow the judiciary to strike down legislation through judicial review, amount to letting non-legislative powers interfere with the legislature's business of creating new law.
Another problem bedeviling the tripartite notion is that it is hard to see why we would want it. Sometimes enthusiasts for the separation of powers speak as if the idea is to have three opposing institutions running the country in order to keep them busy jostling for power among themselves. But why (you might ask) is that meant to be a good idea? The thinking is that the internal jockeying for power will keep the institutions distracted from doing what people with political power normally do – namely, to enrich themselves by oppressing everyone else. They're too busy dealing with the in-fighting to achieve the type of full-throttle exploitation and extortion that despots usually manage to achieve.
That's the theory, anyway. And maybe there is something to it. But, if so, we're going to take a lot of convincing. Creating internal divisions in an institution, after all, is not normally a good policy for ensuring that institution runs well. Usually the reverse is true.
A better way of thinking of the separation of powers is to see it as a grab-bag of clever strategies for structuring political institutions so as to stymie their capacity to behave badly. If we go back to the major political theorists developing the separation of powers – figures such as Montesquieu, Locke, Madison, Kant and Machiavelli – we do not find a clean tripartite division. We find a series of insights about how attending to the inter-relations between institutions can help ensure those institutions perform their intended roles.
Sometimes these strategies include creating sharp divisions between organizations, so as to make sure that specific tasks are performed by those best-suited to perform them, or to avoid an obvious conflict of interest.
More often, though, creating sharp divisions is not good policy. Instead, dividing the institutions is only half the story – the first half of the story. The real purpose of separating institutions is to create new inter-connections between them, or to share a larger task across them, in order to secure a better outcome.
In a nutshell, we separate only to re-connect.
Perhaps the single most powerful way a government can injure a citizen is by arbitrary arrest and prosecution, and perhaps its single most dangerous occurrence happens when such arrests are politically motivated, such as the arrest of opposition figures and dissidents.
Consider how the separation of powers quells such dangers. An individual judge cannot physically arrest a citizen and gather evidence against her—nor can the judge create a law targeting that citizen. For that the judge needs the police (a part of the executive). Equally though, the police can arrest the citizen, but cannot judge and punish her. For that they need the judge.
This means that the state can only deliberately target particular persons when the bodies conspire in their persecution, for then the police can make a fabricated arrest, sure in the knowledge that the judge will sentence their victim. So too, if the reigning faction in the legislature wants to imprison members of the opposition, then they must conspire with both the executive and the judiciary to do so.
Having separate institutions performing these roles does not prevent conspiracies from happening. Of course, members of the legislature can collude with members of the executive and the judiciary. But the real trick of the separation of powers is that it requires such a conspiracy to occur. Such nefarious schemes are much easier to manage when one small clique, in a single institution, controls all these levers of power. Conspiracies, on the other hand, are notoriously fraught enterprises when they begin to span over many different people at different institutions.
In such ways as these, the separation of powers doesn't seek to make political repression and the abuse of power impossible. It just makes it much harder, and much riskier, than it would otherwise be. (This is why the first thing that despots like Hitler do when they come to power is to sweep aside such separations, and gather all the levers of power under their own direct control.)
But why – you might ask – is it helpful to have multiple institutions with different roles in various processes? If it is sensible to distrust one institution acting alone, why shouldn't we harbor the same distrust (twice the distrust!) for two institutions, each potentially abusing their power as they vote and veto?
Theorists like Montesquieu, Locke and Madison actually provide an array of sophisticated answers to such questions. I've summarized some of these into a little set of theorems:
In what we might call the 'one good apple' theorem, if we spread the performance of a given activity across multiple actors, then if just one actor in the chain acts in good faith (or if her self-interest tends to align with the public interest), then she can thwart all manner of evil enterprises.
On another approach, 'the non-aligned interests' theorem points out that even if various people want to abuse their power by enriching themselves and persecuting their enemies, if they are not part of the same group in the same institution, they probably will not share the same ideas on who should get rich and who should get persecuted. Because there is a separation between the groups, each has self-interested reason not to be complicit in the others' schemes. Why should they help someone else get power and wealth? On this footing, the separation of powers takes advantage of the natural resistance of selfish people to do anything outside their narrow self-interest.
Next, the 'aligned legitimate interests' theorem points out that even completely self-interested agents will always have at least some interest in doing the jobs they are supposed to do. By effectively performing her role, an agent increases the legitimacy of her institution, and cements her own authority within it. Also, as a member herself of the general citizenry, the institutional agent benefits from the existence of social peace and liberty created by a functioning political regime. As such, if all the self-interested, biased ways of performing her role are vetoed by checking powers (in line with the non-aligned interests theorem above), then the agent is left only with her remaining non-partisan interest, which is to enhance her status and the status of her institution by actually performing her role well.
All proceeding according to plan, the separation of powers might therefore pull off a quite remarkable feat: through its strategic separations and re-connections, it might entice a myriad of mostly self-interested actors to act in the public interest.
Summing up, the separation of powers (as we find it in Montesquieu, Locke, Madison etc) gathers together a host of insights for structuring institutions so as to make those institutions more likely to be productive and honest. It is based on a realistic assessment of human nature, accepting that bad people will sometimes get into power, and that power will sometimes tempt good people to do bad things.
Separating supreme political power across institutions does not stop bad people getting into power. But, in drawing on an array of insights about human nature, the separation of powers makes it harder for bad people to do bad things. It is for this reason that so many early Enlightenment political theorists seized upon the separation of powers as a weapon against despotic and absolutist governments. Faced with supreme monarchies, the Enlightenment philosophers realized the wisdom of dividing and conquering. They aimed to separate the powers, but only in order to reconnect them in subtle and ingenious ways – ways that tended to make corruption, despotism and the abuse of power harder and riskier.
(In this blogpost I have expressed all these insights in a very summary fashion, and of course more argument and defence would be required to show how they can combine in fruitful ways, and the conditions under which they will tend to work. Again, for those interested in knowing more, the issues raised here are dealt with in detail in Hugh Breakey (2014). Dividing to conquer: Employing the separation of powers to structure institutional inter-relations. Research in Ethical Issues in Organizations, 12, 29-58). (During July 2015, the Article may be downloaded for free.))
2 comments:
- William Ferguson said...
So this leads to an interesting thought. Is separation of concerns the solution to ensuring that AIs remain mankind's helpers and not overlords?
William Gibson proposed a similar mechanism in Neuromancer.
- July 2, 2015 at 8:29 PM
- Hugh Breakey said...
That is an interesting thought. Maybe instead of creating just one AI, we need to make sure we create multiple AI, and divide power among them!
Still, the separation of powers works, at least in part, because differently situated human beings struggle to join together in nefarious schemes. This is what makes large-scale conspiracies so difficult to pull off. If the AIs can assimilate and communicate better with each other, then it might not work as effectively. (So we need to make sure they are each built on incompatible platforms?!)
- July 2, 2015 at 9:03 PM
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Contact and Support
Grab Some Help!
The fastest way to get help is to visit our GiggleBot Support Page here.
You can also click the "Help" button towards the bottom of the screen!
You can also contact us on our company website, Dexter Industries.
You can learn more about Dexter Industries and our other robots such as the GoPiGo, the BrickPi, and the GrovePi here.


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Crosby: Sullivan helped me improve this season
Penguins center says struggles turned around with new coachby Tom Gulitti @TomGulittiNHL / NHL.com Staff Writer
CRANBERRY, Pa. -- After Mike Sullivan was hired to coach the Pittsburgh Penguins on Dec. 12, one of the first things he did was sit down individually with the players in the team's leadership group.
That, of course, included captain Sidney Crosby, who had gotten off to a slow start with six goals and 13 assists in the first 28 games of the season under fired coach Mike Johnston. Although the speculation Crosby's days as dominant player might be over at age 28 was off base, there definitely was something missing from his play.
From having coached against Crosby often during his five seasons as an assistant with the New York Rangers, Sullivan thought he knew what it was.
"This game, it's an emotional game and it's hard to be good in the absence of it," Sullivan said Tuesday. "We have to have controlled emotion, we have to channel it the right way, but emotion is a necessary part of competitive advantage and excelling in this game. And, from my experience of coaching against Sid, that's when he's at his best, and some of the early conversations that I had with Sid when I first took the team over was to try to light that fire in his belly that makes him so great."
Video: Crosby scores first career OT goal to even ECF
Fast forward to Game 2 of the Eastern Conference Final against the Tampa Bay Lightning on Monday, and it's clear Crosby's fire is burning brightly now. Having been held without a goal for the eight previous games, Crosby appeared determined to end his drought; he had six shots on goaltender Andrei Vasilevskiy and delivered five hits.
Crosby finally was rewarded when he scored 40 seconds into overtime to give the Penguins a 3-2 victory that evened the series 1-1 as it shifts to Amalie Arena for Game 3 on Wednesday (8 p.m. ET; NBCSN, CBC, TVA Sports).
Sullivan pushed a lot of the right buttons Monday, as he has often since he took over the Penguins, including shuffling his line combinations to put Chris Kunitz on Crosby's left wing in place of the struggling Conor Sheary to begin the third period. Sullivan's decision to sit defenseman Olli Maatta also paid off, because Justin Schultz played a solid game in his place and the coach's faith in Matt Murray was rewarded with the rookie goaltender rebounding after a rough first period to hold the Lightning off the board the rest of the way.
Sullivan didn't deny he considered replacing Murray with veteran Marc-Andre Fleury after the first period, but Murray was grateful his coach stuck with him.
"It was only two goals, so I don't think I deserved to be pulled or anything like that, but I definitely appreciate him giving me that chance," Murray said. "You never want to come out of a game. You always want to be in there whether you're struggling or not and battle through it, and that's what I did [Monday]."
Crosby does not underplay the impact Sullivan has had on his play, saying, "He definitely helped me." The proof is in his performance.
Video: Crosby's OT winner gives Penguins 3-2 win in Game 2
In 50 regular season games after the coaching change, Crosby had 66 points (30 goals, 36 assists). Although Crosby went through a scoring lull in the second round against the Washington Capitals, he still ranks second on the Penguins with 12 points (four goals, eight assists) in 13 games in the Stanley Cup Playoffs and is heating up with points in four of the past five games (one goal, three assists).
"When there's a coaching change, especially as a captain you take a lot of responsibility on your shoulders and you expect more," Crosby said. "I wasn't happy with the way I started, and I think he just put me in situations and gave me opportunities to try to work my way back into things. He was just good holding everyone accountable, myself included, and making sure that I got better."
Crosby recalled how Sullivan set the tone in their relationship in that initial meeting.
"He coached with the Rangers and I've seen him a bunch, so he told me what he expected out of me as far as a player individually and as a leader and things like that," Crosby said. "It was pretty clear and he was very honest, and that's all you can ask for is for him to be straightforward like that and tell me what he thinks. … And it wasn't just me. I think he was very clear with everyone what he expected from each individual guy and, at that point, it was just a matter of us going out and doing that."
Crosby and the Penguins responded by going 33-16-5 under Sullivan in the regular season and rolled into the playoffs as the NHL's hottest team. After getting past the Rangers and the Capitals in the first two rounds, they need three more wins against the Lightning to reach the Stanley Cup Final for the first time since 2009.
"I thought it was important for me as a coach to establish a relationship with our leadership guys, so I tried to extend myself to all of those guys, but Sid in particular," Sullivan said. "The message that I tried to bring to the whole group was that the foundation of our team identity has to be our competitive spirit. It has to come from our passion to play, and so I tried to challenge these guys and Sid in particular to play with that necessary emotion. … And I think [with] our group certainly, the message resonated and we have a team right now that plays with competitive fire."


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Risk Management for Property Managers
Live seminar or downloadable video.
Manage, reduce or eliminate common risks encountered by Alabama landlords and property managers. Open to public, also earns 3 hours of Level 2 Risk Management for Alabama real estate licensee, AREC course #710CE credit for live classes only. Video does not earn CE credit.
See Cities and Dates, just above the "Add to Cart" button.
Click Topics tab for details, and Handouts tab for materials you will be able to download as soon as you register.
- Choice of business entity
- Animals - including pets, dangerous animals & emotional support animals
- Sex offenders
- Mold, bedbugs, meth production
- Problem tenants
- The Feds--Fair Housing, Fair Credit, Fair Debt Collection, DEA forfeitures
- Premises liability to 3rd parties
- Protecting premises from tenants and others
- Sexual harassment
- Conflicts of interest
- Employee dishonesty
- Lawyers, accountants and other contractors
- Property management contracts as risk management tools
- Lease as risk management tool
- Insurance
- Software
- Disaster risks
Immediately after registering, you will receive an email with links for all downloadable class handouts. All materials copyright protected. If you purchased the streaming video, the email will also contain a link for the video course.
- Class slides
- Slide show regarding animals and tenants
- Instructions for free online maintenance/repair request management
- Sample Adverse Action Letter
- Handling the Reasonable Accommodation Request
- Federal lead-based paint pamphlet (English)
- Federal lead-based paint pamphlet (Spanish)
- Lead based paint disclosure form (English only)
Customer Reviews
Great class, Instructor is very knowledgable on all topics related to risk and Landlord Tenant law.
Risk Management for Property Managers Seminar
In the world of property management, I have realized that there is no world like it! I feel like I am lost on a planet of disgruntled tenants and people that I will never be able to satisfy- no matter what I do! But the key is to have the answers. To know what you are doing. Denise helps with that. She is a world of knowledge and every time I take her classes, I feel equipped and confident in what I am doing.
Property Management is a tough business. There are so many risks and so many different circumstances that can lead us possibly to court! After taking Denise's class, and learning about what I can and cannot do as a property manager, has allowed me to assist my owners in a more professional and confident way. Our owners look to us for advice and it is so important to have accurate information to give them. I would recommend taking this class at least twice a year to just make sure you are up to date on all the Risk Management procedures. I recommend taking this class with Denise! Her experience, and knowledge is just mind blowing. You will definitely walk out of class feeling as though you are equipped and knowledgeable to take on anything that comes your way. She makes learning so fun and easy. She allows you opportunities to ask questions that she always has the answers to. Whether you are managing 10 or 100 properties, the information that you will learn while taking her class will benefit you and take your business to the next level!
Yesterday I attended Denise Evans' Landlord/Tenant classes that were held in Mobile Al. They were both full of valuable information that I could use in the day to day operations and management of our rental properties. I took pages of notes! We had just the right amount of breaks, and there was never a lull. The class instructor was very knowledgeable, and was very helpful in answering the many questions the class asked. Joanne Anderson, Broker, Mobile
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tag:blogger.com,1999:blog-6637204571906679962019-07-13T02:24:50.650-07:00Statistical programming in medical researchPaul M Brown, Scientist, email@example.com:blogger.com,1999:blog-663720457190667996.post-54467693400185324972018-06-19T20:40:00.002-07:002018-07-22T02:41:14.925-07:00Unexpected results and defensive coding19 June2018

 Defensive coding is an important part of Good Programming Practice (GPP) and has been defined as "an approach to programming intended to anticipate future changes of the data that might influence the coding algorithms. Ideally programs should be written in such a way that they will continue to work correctly in case of new or unexpected data values which did not exist at the time the code was developed" [ref]. This is especially important if we develop the code on a subset of data, so the analyses can be generated as soon as the final data become available.

 For example, when when selecting a lab parameter we may write the code as "if upcase(param)=RBC" (RBC=red blood cells). We expect the text variable param to be in uppercase, but if the text is in lower case, mixed case or upper case, this code will work because of the use of the upcase function. Or, if we want to select patients who experience adverse events we may write "if upcase(AE)=:'Y'". The use of "=:" ensures that we catch 'Y', 'y', 'yes', 'Yes' and 'YES'. Another very common mistake made by programmers new to SAS is to write e.g. "if age lt 20 then agecat='<20'". This ought to be "if age ne . and age lt 20 then agecat='<20'" because SAS treats missings as negative infinity and we should always allow for the possibility of missing data, even if it is not expected.

 Defensive coding requires us to anticipate unexpected results (an oxymoron perhaps). Consider the following code and resulting output:

 The code has not worked and the result is unexpected. We should instead merge the data sets first and then in a second data step add the asterisk to sex. Consider another example:

 Again, the result is not what we desire. If the variable being amended (in this case var2) exists on the first data set, then we do not have this erroneous result.

 Finally, it is important to search the log for the right terms when confirming the program has run without a hitch. I guess most programmers maintain a list of such terms. Personally I search for: error, warning, repeat ("merge statement has more than one data set with repeats of by values"), multiple ("multiple lengths were specified for the variable"), gener ("missing values were generated as a result of performing an operation on missing values"), initial (variable is "unitialized"; note the American spelling).

email@example.com:blogger.com,1999:blog-663720457190667996.post-62878834185233622712018-06-17T20:58:00.003-07:002018-07-22T02:39:18.341-07:00Last-observation-carried-forward17 June 2018

 Last-observation-carried-forward is no longer a preferred method of imputation. It is considered quite crude and susceptible to bias, especially in e.g. Alzheimer's disease (EMA points to consider on missing data), and more sophisticated methods are favoured such as multiple imputation and mixed modelling when there are repeated measures over time. However, the code once used routinely to carry the last observation forward may be useful in analogous situations. Barbalau has described different ways of coding LOCF [ref]. I prefer to use the retain statement as follows:

 Incidentally, the retain statement can also be used to order variables in a dataset, but care must be taken (see SAS help).

email@example.com


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Travel Special: Land of the Sheep part 2
We're excited to say that we managed to get a great response to the first part of this series, as it was featured on one of DC's hottest morning shows: Kane in the Morning on Hot 99.5! So back by popular demand is our Travel Special: Land of the Sheep.
The investigation into the backers of GodTube is not yet completed, but we do expect to bring new and exclusive information to you soon, so "don't touch that dial" as they say in radio land.
Today I'd like to invite my followers into the Church of the iPod. Our pastor is teaching the theology of the iPod and Apple. Specific topics include creating trendy trinkets, wasting countless dollars on materialistic consumer goods, and listening to Christian Rap. This guy has a winner. Apparently this is a 30 second spot for an actual sermon series that took place last year in Houston. Rock on GodTube!


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Company Introduction, Market Segmentation, and Product Positioning
Question Description
In this assignment you will describe your fictitious company and
provided its background. Then, you are ready to start building the
marketing plan with a focus on segmenting and positioning your product
and service.
Write a five to seven (5-7) page paper in which you:
A. Write about your company.
1. Write a detailed company background. Address the following items at a minimum for full credit:
2. Create a strategic mission statement.
3. Determine and decide upon at least one (1) foreign market for the product and service. Provide your rationale for this market.
B. Write about your marketing plan.4. Discuss the potential audiences for a marketing plan and the needs of those potential audiences.
5. Identify the marketing segment for the product and provide a rationale for this segment.
6. Discuss the target market and provide a rationale for this target market.
7. Perform a SWOT analysis (strengths, weakness, opportunities, and threats) for the company.
8. Create the market position for your product and service. Explain your rationale.
9. Support your marketing plan with at least two (2) reference sources that discuss the nature of the product.
Your assignment must follow these formatting requirements:
- Be typed, double spaced, using Times New Roman font (size 12), with one-inch margins on all sides; citations and references must follow APA or school-specific format. Check with your professor for any additional instructions.
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- ValuePad Touch-U stand for silicone substrates / support for iPhone 5, 4, iPod Touch / Nano, iPad Mini, Samsung Galaxy, Dell Streak / Venue, Nexus, Acer Iconia, mobile phones, smartphones and 7-inch or smaller tablets.
- High-quality silicone materials. Attached to the rear side of the devices with the supplied double-sided adhesive tape. When removing, there are no leftovers.
- Stylish and compact design. Click to activate the rebound band and conveniently maintain your devices. When not in use, press it against. Works better on 7-inch or smaller devices.
- Economical OEM packaging
- Contact our center in Houston, TX to expedite sales, returns, refunds and any other services.
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Horse Girl by Akina Cox
"Horse Girl," a new artist book by Akina Cox. A love letter to horses and the women who love them, "Horse Girl" explores not only Cox's longtime infatuation with horses, but also the symbiotic relationship developed between horses and women throughout history.
4.25" x 5" Risograph Zine
Akina Cox graduated from CalArts with an MFA in 2012. Her work has been included in exhibitions at Commonwealth and Council, Monte Vista Projects, and LACE. Her collaborative projects have been exhibited at the Center for the Arts Eagle Rock, as well as ForYourArt and the Santa Monica Museum of Art. Her artist books have been published by New Byzantium Press and Golden Spike Press, and can be purchased at Otherwild, and the MOCA Bookstore in Los Angeles, Art Metropole in Toronto, and Printed Matter in New York City. She lives and works in Los Angeles.


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The first 74 pages of this book were a bit ho-hum and I wasn't quite sure where it was headed. Then on page 75, the author serves up the most delicious looking carrot that keeps you chasing for answers right up until the end.
The three main characters are Mikael Blomkvist, Henrik Vanger, and Lisbeth Salander. Blomkvist is an investigative reporter who suffers a major blow to his writing career and magazine company. Vanger is the elderly head of a centuries-old family corporation. Despite his age, he's still as sharp as a tack and is eager to have the biggest mystery of his life examined by the unemployed Blomkvist in hopes of securing some answers before he dies. Forty years prior, Vanger's niece, Harriet, vanished from the family estate without a trace, and Vanger suspected foul play within the family.
Salander's character deserves a paragraph all her own. She's a teeny, tiny, anorexic looking 25 year-old in the body of a 14 year-old boy. She also sports a punker look, with jet black hair, oodles of tattoos, and a fair number of piercings. You can tell right off the bat that she's a deeply scarred and extremely guarded individual. While we never get too much information about the experiences she went through as a child, we do learn that she has been declared mentally incompetent by the state, a verdict handed down not because of her lack of mental aptitude, but because she refused to cooperate with any psychiatric evaluations. In fact, she's the most gifted computer hacker in Sweden, has a photographic memory, and can process an insane amount of information in a very short amount of time in her job as a free-lance private investigator. As Blomkvist's investigation begins to intensify, he and Salander team up to nail both the Vanger family fiend and the business mogul who trashed Blomkvist's reputation. They are quite the dynamic duo.
At the beginning of each section, Larsson offers a statistic on sexual abuse against women in Sweden. It wasn't until I got 3/4 of the way through the book that I realized the significance of those statistics. Not only is Salander attacked, but Blomkvist's investigation of the Vanger family leads to some seriously, seriously, disturbing secrets that have been perpetuated for 40+ years.
What threw me for a loop, though, was the double-message the author seemed to give. On one hand, he seemed to glorify–if not deify–sex and promiscuity among the characters in the story; yet, on the other hand, makes a huge statement about abuse against women. I challenging to explain why it bugged me, but it did.
Off to read the next book in the series…I'm hoping it'll shed some more light on Salander's past!


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Epigenetic study of early childhood
Due to the rapid development of scientific disciplines that arose at the intersection of biology and psychology (psychophysiology, neuropsychology, psychogenetics), the use of biological methods in psychological studies is increasingly actual.
One of the promising interdisciplinary areas in terms of research of deprivation impact on human development is behavioral epigenetics. This new psychogenetic branch studies the role of epigenetic mechanisms in the formation of behavioral phenotype under the influence of environmental factors. Currently a special research interest is focused on the transformations of the epigenome (changes in gene expression regulation mechanisms) associated with early adverse external conditions. These transformations are supposed to result in long-term consequences for the physical and mental development and health of the child.
One of the major epigenetic mechanisms of regulation of gene activity is DNA methylation – a process consisting in attachment of a methyl group (CH3) to cytosine, which eventually leads to suppression of expression of the corresponding gene. The set of methylated regions of the genome constitutes structures specific to different types of cells – DNA methylation patterns (Strathdee and Brown, 2002).
The studies of SD Suomi, HF Harlow, SD Kimball, D. Liu, DK Day, carried out on animals, revealed that the early separation from mother has negative effects on the offspring`s behavior and health (Suomi et al., 1971; Liu et al., 2000). Researchers D. Chiccetti, MR Gunnar, M. Dozier, KO Ladd received data confirming the negative impact of early adverse experience on human development (Cicchetti, 2002; Ladd et al., 2000). Furthermore, the study of mental and physical health of children from social institutions conducted by TG O `Conner, MR Gunnar H. Fox, C. Nelson, Ch Zeanah allowed to draw conclusions about the difficulties in the development of emotional, cognitive, motor and communicative spheres of these children (O'Connor et al., 2000; Zeanah et al., 2003).
Negative childhood experience is associated with the risk of a wide range of diseases and behavioral problems in later adulthood (Felliti et al., 1998; Shonkoff et al., 2009). Epidemiological studies show that a range of diseases, such as cardiovascular disease, diabetes, obesity, depression, substance abuse, premature aging and others have their determinants in the early stages of development (Harkonmaki, 2007; Shonkoff et al., 2009; Felliti et al., 1998; Coelho et al., 2014), and a number of them is associated with early deprivation (Kreppner et al., 2007).
Despite the relative "youth" of behavioral epigenetics in general, and studies of epigenetic response to the conditions of early deprivation, in particular, this area is actively being developed by foreign scientists during the last decade. It is reflected in numerous foreign literature reviews in the area (Hoffmann & Spengler, 2014; Lutz & Turecki, 2013; Szyf, 2013). In Russia this area of research remains largely unexplored.
Evidence provided both by animal and human studies support the hypothesis that maternal care has a huge impact on the phenotype of progeny, and that this effect is probably mediated by changes in gene expression and epigenetic regulation of its systems. Consequently, the understanding of the mechanisms involved in the occurrence of the phenomena discussed above, requires the study of "epigenetic response" on a factor of deprivation and its role in shaping the phenotype, in the context of the features of the child's development and long-term effects of deprivation conditions on mental and physical health.
Epigenetics is the science that deals with the study of gene expression changes caused by mechanisms that do not affect the DNA sequence. Epigenetic mechanisms are numerous and complex, with basic one represented by RNA interference, chromatin reconstruction, histone modification and DNA methylation (Turner, 2001). However, we will focus on discussing the DNA methylation. DNA sequence has some specific sites where the methyl group can attach to cytosine using enzymatic reactions. Such sites are usually located within the regulatory regions of gene, near the promoter preceding the initial transcription site. Thus, methylation is a covalent modification of DNA by attachment of a methyl group (CH3) to cytosine contained in the dinucleotide sequence cytosine-guanine (CpG), which leads to suppression of gene activity. At the functional level methylation restricts access of transcription factors and RNA polymerase to the DNA. The link between cytosine and methyl group is very strong, which results in stable, although potentially reversible changes in expression. Patterns of DNA methylation are saved during cell division and are transferred, thus, to the daughter cells, and it is through this mechanism that cell differentiation occurs (Turner, 2001). An important direction is behavioral epigenetics – young psychogenetic area, which aim is to study the patterns of environmental influence on the epigenome and the phenotypic manifestations of such interaction, which include, in particular, the emergence of various diseases, certain forms of behavior and trajectories of mental development.
The molecular basis of long-term effects of maternal deprivation on progeny phenotype was first demonstrated in a series of experiments with rats conducted by Moshe Zif and Michael Meaney. The researchers observed the behavior of rats exhibiting high and low level of care to their offspring, and then examined the differences in mRNA hippocampal glucocorticoid receptors in the latter (Weaver et al., 2004). At the phenotypic level rats reared by caring mother, showed blunted reaction to a stressful situation from the hypothalamic-pituitary-adrenal axis, and also showed a lower incidence of anxious behavior (Meaney et al., 1996; Liu et al., 1997). It was noted that a high level of caring behavior in mothers changed epigenome of progeny rats at promoters of genes encoding the glucocorticoid receptors of the hippocampus. The researchers found differences in DNA methylation in pups reared by caring mothers, compared with the offspring of inattentive mothers. The level of glucocorticoid receptors in the hippocampus regulates HPA axis response to stress on the feedback principle: a high level of activity of mRNA glucocorticoid receptor corresponds with poor response to stress (Jacobson and Sapolsky, 1991).
There are also studies concerning the possibility of transferring the effects of early experience through the generations. For example, T. Franklin on the basis of observations over mice, subjected to prolonged and unexpected separation from the mother during 14 days after birth, succeeded to show that prolonged separation entails manifestation of behavior peculiar to depression at an older age and changes their behavioral reactions towards negative and dangerous environmental factors. Such behavioral changes appeared later in progeny of mice who had experienced maternal separation, in spite of the fact that they grew under normal conditions. Long and unpredictable separation from the mother has also changed the profile of DNA methylation in promoters of several candidate genes of germline in separated males. Similar changes in DNA methylation associated with altered expression of genes have been identified in the brains of their offspring. Described data illustrate the vast deleterious effects of stress on early development and behavioral responses, transmitted across generations through the regulation of DNA methylation. Mouse model presented here reproduces the multiple effects of early stress on behavior and reflects the unique and unprecedented model of inherited behavioral disorders due to early stress. (Franklin et al., 2010).
There are also attempts to study the applicability to human of the thesis, developed on the basis of studies in animal models. Recently there were described studies on genome-wide changes in DNA methylation in peripheral tissues after the experience of interaction with adverse early environment. In the first study, an attempt was made to trace the link between DNA methylation in blood and evidence of early abuse, post-traumatic stress disorder and exposure to stress (Smith et al., 2011). While differential methylation in gene 1 and 5 associated with PTSD and stress, there were found no statistically significant results on the experience of early violence. In another study in the saliva of children who have experienced abuse at early age there were found 2600 CpG sites, which methylation level was different from the level of methylation in children, who have never faced with violence and had no mental illness (Yang et al., 2013). Along with the previous findings, these studies suggest that the violence faced in early childhood, and the related stressor experience have profound genome-wide epigenetic consequences for peripheral tissues.
Of particular interest to us is the study conducted recently by O. Naumova and colleagues, which checks for a connection between the experience of deprivation conditions in early childhood and changes in gene expression (Naumova et al., 2012). The aim of this study was to compare the genome methylation patterns in children-orphans and children from biological families. Comparative analysis of methylation of two groups of children identified about 800 differently methylated gene and showed that the most important intergroup difference was the increased level of methylation of the genomes of children in orphanages, as compared with children living in biological families. Thus, there were many high-methylated genes in children from these institutions, which play an important role in controlling the immune response and cell signaling systems as well as in the development and functioning of the brain.
Our interdisciplinary research project called «Impact of early deprivation on bio-behavioral indicators of child development» represents another attempt to study change of the epigenome in early childhood, in the context of various and dynamic social environments – institutional care (IC), foster care (FC) and typical family environment (typically developing, TD). The research is a cross-sectional study of the complex of behavioral, neurophysiological and epigenetic indicators of children.
Our hypothesis is that institutional care may cause systematic changes in the DNA-methylation profiles of children, that in turn may exert an impact on biological and behavioral levels of the children`s development. These alterations may be neutralized or reversed with changes in care, such as the children's placement into foster families.
The study involves a sample of children with Down syndrome, which gives an opportunity to examine the character of epigenetic perversions in their genomes. We hypothesize that analysis of data collected will provide new evidence on global alterations in the epigenome related to trisomy, and will allow to identify some features of epigenetic patterns associated with cognitive impairments in DS children.
We suggest that our unique data will provide significant results of epigenome-wide association with behavioral phenotypes on early stages of the development.
1 Cicchetti, D. The impact of social experience on neurobiological systems: Illustration from a constructivist view of child maltreatment // Cognitive Development. 2002. Vol. 17. pp. 1407-1428.
2 Coelho, R., Viola, T.W., Walss-Bass, C., Brietzke, E., & Grassi-Oliveira, R. Childhood maltreatment and inflammatory markers: a systematic review // Acta Psychiatrica Scandianvia. 2014. Vol. 129. pp. 180-192.
3 Felliti, V.J., Anda, R.F., Nordenberg, D., Williamson, D.F., Spitz, A.M., Edwards, V., & Koss, M.P. The relationship of adult health status to childhood abuse and household dysfunction // American Journal of Preventitive Medicine. 1998. Vol. 14. pp. 245-258.
4 Franklin T.B., Russig H., Weiss I.C., Gräff J., Linder N., Michalon A., Vizi S., Mansuy I.M. Epigenetic Transmission of the Impact of Early Stress Across Generations // Biological Psychiatry. 2010. Vol. 68. pp. 408-415.
5 Harkonmaki, K., Korkeila, K., Vahtera, J., Kivimaki, M., Suominen, S., Sillanmaki, L., Koskenvuo, M. Childhood adversities as a predictor of disability retirement // Epidemiol Community Health. 2007. Vol. 61(6). pp. 479-484.
6 Hoffmann, A., Spengler, D. DNA memories of early social life // Neuroscience. 2014. Vol. 264. pp. 64-75.
7 Jacobson, L., Sapolsky, R. The role of the hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis // Endocrine Reviews. 1991. Vol. 12. pp. 118-134.
8 Kreppner, J.M., Rutter M., Beckett C., Castle J., Colvert E., Groothues C., and Hawkins A. Normality and impairment following profound early institutional deprivation: A longitudinal follow-up into early adolescence // Developmental Psychology. 2007. Vol. 43. pp. 931-946.
9 Ladd, C.O., Huot, R.L., Thrivikraman, K.V., Nemeroff, C.B., Meaney, M.J., & Plotsky, P.M. Long-term behavioral and neuroendocrine adaptations to adverse early experience // Progress in Brain Research. 2000. Vol. 122. pp. 81-103.Liu et al., 1997
10 Liu, D., Diorio, J., Day, J.C., Francis, D.D., & Meaney, M.J. Maternal care, hippocampal synaptogenesis and cognitive development in rats // Nature Neuroscience. 2000. Vol. 3. pp. 799-806.
11 Lutz, P., Turecki, G. DNA methylation and childhood maltreatment: From animal models to human studies // Neuroscience. 2013. In press.
12 Meaney, M.J., Diorio, J., Francis, D., Widdowson, J., LaPlante, P., Caldji, C., Sharma, S., Seckl, J.R., Plotsky, P.M. Early environmental regulation of forebrain glucocorticoid receptor gene expression: implications for adrenocortical responses to stress // International Journal of Developmental Neuroscience. 1996. Vol. 18. pp. 49-72.
13 Naumova, O.Yu., Lee, M., Koposov, R., Szyf, M., Dozier, M., Grigorenko, E.L. Differential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents // Development and psychopathology. 2012. Vol. 24. pp. 1.
14 O'Connor, T.G., Rutter, M., Beckett, C., Keaveney, L., Kreppner, J.M., & the English and Romanian Adoptees Study Team. The effects of global severe privation on cognitive competence: Extension and longitudinal follow-up // Child Development. 2000. Vol. 71. pp. 376-390.
15 Shonkoff, J., Boyce, W.T., & McEwen, B.S. Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention // Journal of the American Medical Association. 2009. Vol. 301. pp. 2252-2259.
16 Smith, A.K., Conneely, K.N., Kilaru, V., Mercer, K.B., Weiss, T.E., Bradley, B., Tang, Y., Gillespie, C.F., Cubells, J.F., Ressler, K.J. Differential immune DNA methylation and cytokine regulation in post traumatic stress disorder // American Journal of Medical Genetics Part B-neuropsychiatric Genetics. 2011. Vol. 156B. pp. 700-708.
17 Strathdee, G., Brown, R. Aberrant DNA methylation in cancer: potential clinical interventions. Expert // Expert Reviews In Molecular Medicine. 2002. Vol. 2002. pp. 1-17.
18 Suomi, S.J., Harlow, H.F., Kimball, S.D. Behavioral effects of prolonged partial social isolation in the rhesus monkey // Psychological Reports. 1971. Vol. 29. pp. 1171-1177.
19 Szyf, M. DNA Methylation, Behavior and Early Life Adversity // Journal of Genetics and Genomics. 2013. Vol. 40. pp. 331-338.
20 Turner, B. Chromatin and Gene Regulation / Blackwell Science Ltd., Oxford: 2001.
21 Yang, B.Z., Zhang, H., Ge, W., Weder, N., Douglas-Palumberi, H., Perepletchikova, F., Gelernter, J., Kaufman, J. Child abuse and epigenetic mechanisms of disease risk // American Journal of Preventive Medicine. 2013. Vol. 44. pp. 101-107.
22 Zeanah, C.H., Nelson, C.A., Fox, N.A., Smyke, A.T., Marshall, P., Parker, S.W., & Koga, S. Designing research to study the effects of institutionalization on brain and behavioral development: The Bucharest Early Intervention Project // Development and Psychopathology. 2003. Vol. 15. pp. 885-907.


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Azelis Construction Solutions
In 2004, our company noticed that there was a major hole in the construction industry so we began using our current warehouses to offer technical services and support to this segment. We quickly realized that, while this was a good start, it wasn't nearly enough to satisfy this very important niche, so we set out to offer customized, expert technical consultation and services to all of our construction customers, no matter where your location. By 2007, we built three dedicated state-of-the-art construction labs throughout the United States: one in City of Industry, CA, one in Covington, GA and one in Oak Creek, WI. And in July 2013, we officially expanded our business into Canada by opening our very own distribution warehouse in Toronto.
Today, we're proud to provide the highest level of technical support and customized solutions available today. Since we've got the resources and know-how right at our fingertips, you can count on us to deliver your solutions quickly and efficiently time and time again. No one else offers the value-added services that we can – and it's at no additional cost to our customers…it's just what we do.
Please take a moment and discover what makes Azelis in Americas so unique. We're sure that together, we can formulate solutions that will take your company to the next level.
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We recently announced that Vision Australia Radio is partnering with The Australian Podcast Awards 2019 in Sydney, The Other Film Festival in Melbourne this November and of course again supporting Vision Australia carols by Candlelight this December by providing an audio described version of the event across our nationwide network, now we announce the arrival of an exciting new partnership with Link Disability Magazine.
The partnership that 'links' Vision Australia Radio listeners to the hugely popular and informative disability magazine on radio, is also linking the magazine's readers to the great content we have on offer across our radio network in the way of a 30 minute weekly reading program that is currently undergoing a trial on Vision Australia Radio Adelaide and soon will air across our network in Western Australia, South Australia and Victoria.
As well as reading articles from the magazine so that the blind and low-vision community can also enjoy their great content the program will gradually include more interviews with those featured in the publication to continue the conversation from a VAR perspective.
Through the partnership, Link Disability Magazine is more accessible to people who are blind, have low vision or a print disability, standing true to its charter of being "accessible to all". Link Disability Magazine continues to break down stereotypes, explore taboo topics, generate conversation and support change. As Australia's only cross sector disability magazine, Link Disability Magazine is in its 34th year of providing support, encouragement, connections to services and industry and entertainment.
Keep listening to your local Vision Australia Radio station for more developments around the roll out of the radio program and in the meanwhile, head to our podcast feed to hear what's gone to air in South Australia thus far. You can listen to the first episode by going to this link: https://varadio.podbean.com/e/link-on-air-2-nov-2018/and episode two by heading to this link: https://varadio.podbean.com/e/link-on-air-09-nov-2018/
Vision Australia Radio appreciate the support of Link Disability Magazine and the team at Blend Creative the socially inclusive design firm, for helping us get the program off the ground.


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The Riddle of Monkey Kingdom
From DocuWiki
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Nature Documentary published by NHK in 2009 - English narration
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Manu National Park, Peru, which holds 13 species of monkeys among the various types of Amazonian fauna, is praised as a monkey kingdom. Deep in its jungles is a strange open spot about 20 meters in diameter where a peculiar behavior of monkeys can be observed. The monkeys spend a majority of their time up in the canopies of the rainforest, but come down to the ground to consume gluttonously the soil of the spot. The program looks at how this strange behavior most likely developed in the competition for survival in the Manu's rainforests during the ice age.
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[edit] Technical Specs
Video Codec: h264 ,AVC-1
Video Bitrate: 4000 kbps
Video Resolution: 1280x720
Video Aspect Ratio: 16:9
Audio Codec: AC3
Audio BitRate: 384 kbps
Audio Streams: 2.0
Audio Languages: English
RunTime Per Part: 46 min
Number Of Parts: 1
Part Size: 1.4 GB
Ripped by Hukumuzuku
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[edit] Related Documentaries
- Monkey Kingdom
- Uakari: Secrets of the Red Monkey
- Mystery Monkeys of Shangri-La
- Orangutans: The Great Ape Escape
- Meet The Monkeys
- Capuchins, the Monkey Puzzle
- The Monkey Prince
- Clever Monkeys
[edit] ed2k Links
NHK.The.Riddle.of.Monkey.Kingdom.HDTV.x264.720p.AC3.MVGroup.org.mkv (1435.35 Mb)


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Due to personal reasons Kinfolk have cancelled Thursdays (15th June) performance in the Cellar Bar at South Hill Park Arts Centre , Bracknell and will be replaced by John Cee Stannard & Blues Horizon who are currently promoting their latest album ' to the river'. Support on the night comes from G & T featuring Gillian McCoy & Michael Tuffery. Starting at 8pm, tickets £8.00 in advance and £10.00 on the door. To book tel 01344 484123.
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Earlier Event: June 13Showcase Sessions
Later Event: June 15Richard Digance


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Open Access
MATEC Web of Conferences
Volume 34, 20152015 2nd International Conference on Mechatronics and Mechanical Engineering (ICMME 2015)
|Article Number
|Number of page(s)
|Control theory and technology
|Published online
|11 December 2015
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- Y. Li and S. Song, "A survey of control algorithms for Quadrotor Unmanned Helicopter," in Advanced Computational Intelligence (ICACI), 2012 IEEE Fifth International Conference on, (2012), pp. 365–369. [Google Scholar]
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The Enchantment of Flowers1:33 PM
2 comments
Great story!ReplyDelete
- AnonymousMay 1, 2011 at 12:12 PM
Hi Ellen, well I watched the wedding and was surprised to see, that the bouquet wasn't that big. Most of the time they have large hanging bouquets. Maybe that isn't in fashion anymore. It was a simple bouquet and the dress wasn't over the top too. I believe they didn't want to repeat the wedding of his father and mother, which was a bit over the top. I watched it when I was 16 and I thought it was a living fairytale. The dark end came later and then I realized that it hadn't been a fairytale at all. For neither of the parents.ReplyDelete
I think Kate and William are very smart, trying not to make the same mistakes. I hope for them they will have a long and happy marriage.
I hope your Beltane celebration was great ? Have a fantastic day and Happy Beltane !!


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What's that? You say you've been getting antsy for a brand spankin' new episode of Cyborgs: A Bionic Podcast?
Hosts John S. Drew and Paul K. Bisson continue their bi-weekly retrospective of The Six Million Dollar Man's second season, and for this latest installment, they're joined by Matt Hanksinson, bionic fan extraordinaire who served as a consultant on Time-Life's massive (and frappin' gorgeous) DVD set for The Six Million Dollar Man – The Complete Collection. Matt hops into the third chair to help John and Paul revisit the season's seventeenth episode, "Look Alike."
From John's write-up:
"A doppelganger of Steve has been placed within the OSI, but when he is accidentally killed, Steve decides to take his place and find out who arranged for the duplicate."
Tune in to see what John, Paul, and Matt thought of this latest episode: Cyborgs: A Bionic Podcast – "Look Alike."


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Join Joyce Murray and the Vancouver Quadra team for an afternoon of fun, food, and refreshments as we celebrate our past efforts and gear up for […] More »
The Vancouver Quadra Federal Liberal Association is holding its 4th Annual Spring Celebration with our MP, Joyce Murray and our special guest, the Hon. Carla Qualtrough, MP […] More »
This summer, we have a fantastic opportunity to help lay the groundwork for success in the 2019 election. This starts with us fulfilling the requirements to […] More »
Come join us at Dentry's to celebrate BC's success at the recent Halifax Convention in getting all 3 resolutions into the top 20, 2 in the […] More »
Click here to volunteer at Vancouver Quadra


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The Kebbi Government has registered over 26,000 livestock farmers that would benefit from the Central Bank of Nigeria (CBN) accelerated agricultural development loan scheme.
The Kebbi Commissioner for Animal and Husbandry, Alhaji Adamu Ngaski, told newsmen in Birnin Kebbi on Thursday that the ministry was working out modalities for the disbursement of the loan to the livestock farmers.
The commissioner did not give details of the package and facility to be issued to the beneficiaries.
According to him, the ministry is working out modalities for the provision of loans to the registered livestock farmers through cooperative in the state.
"A comprehensive list of the applicants has been taken, presented to the Central Bank of Nigeria for verification pending the release of the funds to the beneficiaries by the bank."
He urged the applicants to remain patient as the loan would soon be verified and disbursed.
The commissioner denied that the first batch of the farmers had been granted the loan and cautioned people against rumour mongering over the issue.


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Hi! My name is Sophronia Church. You can call me Sophie. Welcome to my blog about Myalgic Encephalomyelitis / Chronic Fatigue Syndrome. I have had CFS/ME for over 20 years. I live in the USA. I am writing this blog to clear up some common misconceptions about ME/CFS and to provide updates to family and friends regarding my condition. This blog will focus on my Ampligen treatments which should begin in May 2011. Thanks for reading!
5 comments
Have you read Kelvin Lord's journal of his year on Ampligen in 2010? http://ampligen-treatment.blogspot.com
Might encourage you.
Hi Sophie,
I was reading some of your blog about how it is easy for you to get infections. I have had CFS since 1982. Last November I developed pneumonia and three courses of antibiotics later I'm still not over it.
Infections are a huge problem for me–they keep popping up all over my body. But the source is clear. I am wifi sensitive. Please get rid of any wireless sources you have such as cordless phones. Try not to use a cell phone and keep it turned off. Use a corded landline. Have your computer hardwired (i.e. hardware any routers, printers, and modems) and disable the wireless feature on all these things.
I haven't figured out how the various frequencies affect me. But I do know that using my computer in wireless mode cases my face to have deep sores. The strong wireless from my neighbor is causing the pneumonia.
Wireless makes body tissues weak and vulnerable to infection.
Thank you for sharing your experiences with us!
I wanted to recommend a very resourceful doctor who specializes in fibromyalgia and CFS–Jacob Teitelbaum, MD–and he knows these conditions as an insider. He contracted CFS while attending medical school and had to drop out for a year to recover. In the ensuing 30 years, he's dedicated his career to finding effective treatment. He's written several books on the topic, including his latest, "The Fatigue and Fibromyalgia Solution" (Avery Penguin, August 6). For more info, check out his website, http://www.vitality101.com and to preorder, http://www.vitality101.com/the-fibromyalgia-and-fatigue-solution.


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Yes-you matter mini-poster
Yes-you matter mini-poster
Wisdom from "an open letter to the next generation of artists" by jazz musicians, Wayne Shorter and Herbie Hancock:
- Each of us has a unique mission. We are all pieces in a giant, fluid puzzle, where the smallest of actions by one puzzle piece profoundly affects each of the others. You matter, your actions matter, your art matters.
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