text:
BMW 535d Drive Axle Assembly Drain & Refill Cost
Know what price you should pay to get your vehicle fixed.
How does a differential work?
As the transmission turns the drive shaft, the drive shaft turns the pinion gear inside the differential. When the pinion gear is turned, it drives the ring gear. That gear combination transfers rotational force from the drive shaft to the drive axles.
Can I drive with a differential fluid problem?
Never drive a vehicle that is very low on gear oil in the differential. There is a strong possibility of damage to the differential, drive shaft, U-joints, and drive axles. If there is only a small leak, and it is caught early, driving the vehicle should not cause any issues.
How often does the differential fluid need to be replaced?
The front differential contains gears and bearings that are lubricated by oil. Like all oils and fluids in a vehicle, the oil in the differential should be changed at the vehicle manufacturer specified interval or more frequently if you use your vehicle to tow or carry heavy loads, or there is a leak in the differential.
What are the symptoms related to a differential fluid problem?
Differentials tend to make excessive noise when they are low on gear oil. The clattering of gears while driving will be a sure sign there is a problem. Also, the traction control light may illuminate in some vehicles, and there may be a loud slapping noise when "D" or "R" is selected.
What is a differential?
The purpose of the differential is to distribute engine energy to the axles so the axles spin the wheels the right way at the right speed. The differential also allows the front wheels to spin at different rates as a vehicle rounds a corner. The inside wheel spins slower than the outside wheel when turning; this "difference" is how the differential gets its name.
How are differential fluid issues diagnosed?
If the gears in the differential are making noise while driving, or a slapping noise when going into gear, but no leak is present, the fluid may need to be changed due to age, or incorrect type.
How is differential fluid replaced?
Replacing gear oil is quick and straightforward. The gear oil is drained from the lower drain plug, or by removal of the differential cover. The differential cover, if not already, is removed, and the differential housing will be cleaned and inspected. If no further repairs are needed, the differential cover is installed, and the differential will be filled with the appropriate type and grade of gear oil.
RepairPal Recommendations for differential fluid changes
There are many brands and types of gear oil available to consumers. Many manufacturers supply a proprietary type that is designed to meet the specifications of that vehicle. They may also indicate optional recommended brands. These recommendations should be followed to help ensure the longevity of the differential.
What to look out for when dealing with differential fluid changes
If vehicles are used in a method consistent with severe duty, as described by the owner's manual, the severe duty service schedule should be followed. This will include a shorter interval for changing differential oil.
Some FWD and AWD vehicles have front differentials that share the differential fluid with the transmission fluid and these two services are essentially one service.
Can I replace the differential fluid myself?
The experienced DIY'er can handle this job with a set of jack stands and a few basic tools and a small torque wrench. This job requires working underneath a raised vehicle, and extreme caution should be exercised. If the individual completing the repair is not experienced with safely lifting and supporting a vehicle, this job should be left to a professional technician.
- Repair shops in Sterling, VA
- Repair shops in Dulles, VA
- Repair shops in Leesburg, VA
- Repair shops in Herndon, VA


text:
GM-CT-01 Plus 5-Fluorouracil as Third- or Fourth-Line Therapy for Metastatic Colorectal Cancer
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00110721
Recruitment Status : Terminated (Study protocol amended to a new treatment regimen: study DAVFU-006.)
First Posted : May 13, 2005
Last Update Posted : March 6, 2012
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Colorectal Cancer
|Drug: GM-CT-01 plus 5-Fluorouracil
|Phase 2
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|20 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase II, Multi-Center, Open-Label Trial to Evaluate the Efficacy and Safety of Intravenous GM-CT-01 in Combination With 5-Fluorouracil When Administered in Monthly Cycles as Third- or Fourth-Line Therapy for Metastatic Colorectal Cancer
|Study Start Date :
|May 2005
|Actual Primary Completion Date :
|June 2007
|Actual Study Completion Date :
|February 2008
- Drug: GM-CT-01 plus 5-Fluorouracil
Single use vials, combined regimen of GM-CT-01 / 5-Fluorouracil (280 mg/m2 /500 mg/m2) given for 4 consecutive days in a 28 day cycle until disease progression.Other Name: DAVANAT
- frequency of objective complete or partial tumor response [ Time Frame: 20 patients completed treatment ]Tumor response as characterized by Response Evaluation Criteria in Solid Tumors (RECIST) criteria
- frequency of stable disease [ Time Frame: 20 patients completed treatment ]Stable disease as measured by CT imaging or carcinoembryonic antigen (CEA) levels
- safety of GM-CT-01 plus 5-FU [ Time Frame: 20 patients completed treatment ]Frequency and type of AE/SAE and ancillary clinical indicators including Eastern Cooperative Oncology Group (ECOG) performance and quality of life.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- 18 years of age or older
- Has a histologically-proven adenocarcinoma of the colon or rectum
- Has documentation of locally advanced or metastatic colorectal cancer not amenable to curative surgery or radiotherapy
- Eligible subjects are those whose unresectable, locally advanced and/or metastatic colorectal cancer has progressed during or after receiving treatment with at least two, but not more than three, lines of therapy that collectively must have included at a minimum all of the following agents: 5-fluorouracil or capecitabine, irinotecan, and oxaliplatin (unless, in the opinion of the investigator, the subject is not able to receive irinotecan and/or oxaliplatin due to medical contraindications, in which case irinotecan and/or oxaliplatin are not required to have been included in the prior lines of therapy). Adjuvant chemotherapy following definitive management of the primary lesion in the colon or rectum is allowed and will not be counted as a line of therapy.
- Has 1 or more measurable lesion(s) ("target lesion[s]") according to RECIST (Response Evaluation Criteria in Solid Tumors) criteria.
The same diagnostic imaging method must be used throughout the study to evaluate the lesions; and clinically detected lesions will only be considered measurable when they are superficial (e.g., skin nodules and palpable lymph nodes).
- Has an ECOG performance status of 0-2
- Has a life expectancy greater than 3 months
- Has the ability to understand the nature of the study and any hazards of participating in it; to communicate satisfactorily with the Investigator; and to participate in, and comply with, the requirements of the entire study
- A female of childbearing potential must have a negative serum screening test for pregnancy and agree to practice abstinence or use an effective method of contraception
- Has had all aspects of the protocol explained and written informed consent obtained
Exclusion Criteria:
- Has central nervous system metastasis
- Has bony metastasis as the sole metastasis
Has other concomitant or previous malignancy in the past 3 years, except:
- adequately treated in situ carcinoma of the uterine cervix;
- basal or squamous cell carcinoma of the skin; and/or
- melanoma in situ.
- Is receiving concomitant anti-neoplastic treatment; has received radiation therapy in the past 3 weeks; has been treated with anti-angiogenesis agents, including bevacizumab, in the past 4 weeks; or has been treated with any other chemotherapeutic agents in the past 4 weeks (6 weeks for mitomycin C and nitrosoureas).
- Has an active infection
- Has congestive heart failure (Class III or IV in the New York Heart Association functional classification system)
- Has a hemoglobin level of < 8.5 gm/dL
- Has a platelet count of < 100,000/mm3
- Has a neutrophil count of < 1,500/mm3
- Has a serum creatinine level of > 2.0 mg/dL
- Has liver aminotransferase and alkaline phosphatase levels that are > 2.5 times the laboratory's upper limit of normal (ULN) in a subject with no liver metastases, and levels that are > 5 times the laboratory's ULN in a subject with liver metastases
- Has a total bilirubin level that is > 2 times the laboratory's ULN
- Has pulmonary DLCO < 60% of predicted
- Has known or clinically suspected infection with human immunodeficiency virus (HIV)
- Has participated within 30 days, or will participate concurrently, in another investigational drug or vaccine study
- Has a history of drug or alcohol dependence in the past 3 years
- Has other serious, non-malignant, significant, acute or chronic medical or psychiatric illness that, in the judgment of the Investigator, could compromise subject safety, limit the subject's ability to complete the study, and/or compromise the objectives of the study
- Has known intolerance to 5- FU
- Has previously participated in a GM-CT-01 clinical trial
- Has known hypersensitivity to GM-CT-01 or any of its components
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00110721
|United States, Connecticut
|Medical Oncology and Hematology
|Waterbury, Connecticut, United States, 06708
|United States, Florida
|Hematology-Oncology Associates of the Treasure Coast
|Port St. Lucie, Florida, United States, 34952
|United States, Louisiana
|Ochsner Clinic Foundation
|New Orleans, Louisiana, United States, 70121
|United States, Michigan
|University of Michigan Comprehensive Cancer Center
|Ann Arbor,, Michigan, United States
|Soroka University Medical Center
|Beer-Sheva, Israel, 84101
|Shaare Zedek Medical Center, Oncology
|Jerusalem, Israel, 91031
Additional Information:
|Responsible Party:
|Galectin Therapeutics Inc.
|ClinicalTrials.gov Identifier:
|NCT00110721 History of Changes
|Other Study ID Numbers:
|First Posted:
|May 13, 2005 Key Record Dates
|Last Update Posted:
|March 6, 2012
|Last Verified:
|March 2012
colorectal cancer
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Colonic Diseases
Digestive System Diseases
Gastrointestinal Diseases
Intestinal Diseases
Rectal Diseases
Molecular Mechanisms of Pharmacological Action
Antimetabolites, Antineoplastic
Antineoplastic Agents
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs

subset: commoncrawl


text:
Crime Can't Win #9, February 1952
Paul Cooper worked as a comic book artist during the 1940s and 1950s. In the second half of the 1940s he was working through Jerry Iger's studio. He has done crime features for D.S. Publishing's 'Underworld', horror stories for Fox Comics and Superior Publishers and contributions to 'Beware', published by Youthful Magazines. In the 1950s, he pencilled romance, crime and mystery stories for Atlas comic books like 'Adventures into Weird Worlds', 'Crime Can't Win', 'Justice Comics' and 'Love Adventures'. From 1954 until about 1956, he was mainly active as an inker, presumably over pencils by Jay Scott Pike.


text:
Crack of dawn, chilly tile floor, staring at yourself in the bathroom mirror, and you're waiting, wondering when the water will get hot. If the fixture is directly over the heater it's a short delay. In a bathroom at the other end of the house you may have a long, water-wasting wait.
A recirculating hot water pipe loop would solve the problem, but most homeowners don't install one because it requires a pump, an electrical line and can be tricky to plumb. Instead, many people turn up the water heater thermostat. It doesn't cost much. The Dept. of Energy says annual operating costs of 50-gallon, gas-fired water heaters is $375. Because a 10-degree rise represents only about four percent of the bill, the thermostat increase costs just $15 to $20.
Two problems. First, the water will be hotter when it gets to the tap but it won't get there any faster. Second, at 130 degrees you can be seriously burned in 30 seconds and at 140 degrees in 5 seconds. Young children can receive scalding burns in half the time at those temperatures. At a sink people may be able to react quickly and pull their hands away. It's more difficult and dangerous in a shower.
Scalding temperatures
Scalding risk is why the Environmental Protection Agency (EPA) and most water heater manufacturers recommend a setting no higher than 120 degrees. There are two exceptions. One is the hot water supply for dishwashers. In most modern units it's boosted by a heater in the appliance to 140 degrees to improve sanitation. In models with stainless steel interiors it can be boosted higher. But in standard models the plastic tub walls can start to deform at about 150 degrees.
The other exception is a misleading number that pops up on many plumbing Web sites: a setting of 140 degrees recommended by the Occupational Safety & Health Administration (OSHA). It's misleading, first, because OSHA regulates the workplace, not private homes. Second, the 140-degree setting is intended mainly to guard against Legionnaires' disease bacteria in commercial heating and cooling plants. But the clincher is just common sense. Yes, 140 degrees might better guard against breeding an unusual disease in your hot water system, but cause many scalding burns in the process. It's not a reasonable tradeoff.
Temperature settings
Unlike furnace and air conditioning thermostats marked in degrees, water heater thermostats typically are marked warm to one side and hot to the other. Actual temps vary, but warm is usually 90 to 110 degrees, and hot is 140 to 150 degrees. Temperature also varies from the thermostat setting up to 20 degrees in the tank — plus 10 as the burner finishes heating and turns off, and minus 10 when the tank has cooled and the burner relights. Instead of guessing, let hot water run a minute or so at a fixture, use a candy or cooking thermometer to measure the temperature, and then adjust the thermostat as needed according to instructions in the owner's manual. On the warm-hot scale it may take a few tries until you find the setting that delivers 120 degree water at the tap.
On electric water heaters the thermostat is buried beneath a removable plate. Many units have two thermostats, one for the top heating element and another for the bottom. Following the owner's manual, shut off the power, remove the panel, and push away any insulation to reveal the thermostat. Most adjust with a flathead screwdriver, right to increase the temperature and left to decrease it. Whatever the calibration (you may see hash marks and no numbers), you'll want to check the water temperature at a faucet once you've changed the setting and let the system resettle for about three hours.
Crack of dawn, chilly tile floor, staring at yourself in the bathroom mirror, and you're waiting, wondering when the water will get hot. If the fixture is directly over the heater it's a short delay. In a bathroom at the other end of the house you may have a long, water-wasting wait.


text:
The photographs of the week from our 5-star hotel in the Tyrol
Memories, emotions and experiences
With great pleasure we are sharing the best snapshots of our 5-star hotel in the Tyrol with you. It was and is lovely to experience time together with you and your family. We are naturally pleased if you also post your best holiday pictures from the Zillertal on your Facebook profile. Many thanks and enjoy yourself when browsing.
Send your photos to: email@example.com


text:
That's what school is, you know. It's a systematized dumping of information upon unwilling students. It's a mass coercion that leads kids - and worse, parents - to believe kids will never know their multiplication tables unless they learn it right now. That they'll never learn how to be quiet unless they start to cooperate right now. That they'll never be able to form a coherent thought unless they practice right now. Which is, naturally, quite ludicrous. And I have the kids to prove it.
In the beginning, it was a paradigm shift of great magnitude to reject this nationally-treasured pedagogical dogma. And that bit of new and profound perspective alone was enough cud for this here grrrl to ruminate on for quite some time. But the decision had been made. I could dwell all I wanted on how and why, but then... something a little more sinister appeared on my radar - how to tell my parents, who'd shelled out tens of thousands of dollars for my out-of-state degree at the #1 School of Education in the nation. And how to tell my husband, who'd been blithely satisfied with a teacher wife, a kindergarten child, and a daycare babe. And how to tell my colleagues I rejected everything about what they spent their life's energy doing. And how to reconcile this new philosophy with everything we'd built our life upon so far.
Yikeys. This wasn't going to be pretty.
But I really had no choice. By the time I quit teaching it had gone far beyond any cerebral level. This was gut feeling, folks. Raw intuition. And it compelled me to change. It compelled me to slam hard on the brakes, step out of the car, slam my head several times on the nearest guardrail, and ask, "Now where in the h*ll did I think I was going?"
And even though I didn't know where, exactly, to go from there, I still knew I had to go. I had to go. Something had turned on inside of me. Some place deep inside had gotten a taste and I craved more. I had always lived in my head, often analyzing and weighing and considering things far beyond what was necessary, to the point of obsession on certain occasions, but for once I felt I'd gotten an answer to a longing. A longing I knew I had, but didn't understand. Up until then I couldn't put a name to it. Up until then I didn't know what would sate it. Until then I didn't know why I couldn't just be content to stay on the mainstream, well-worn path, head up, eyes forward, shoulders back, and keep on going like I was supposed to. >.
I was going with my heart for a change. I always knew there was something lurking just over my shoulder, just out of view. If only I could get a glimpse..
Unschooling has, all along, been as much - if not more - about me as about the children. Of course I dwelled for a long, long time on whether or not it was truly the right path for the children, and would've decided against it had any overwhelming evidence disproving its efficacy presented itself. (Efficacy? Egad, eduspeak!) But it quickly became, simply, 'how things were' for them. It became their normal. It became the only life they knew, their little exposure to school a quickly fading memory. It was for me that it was such a powerful, mind-blowing, planetary-alignment-altering shift.
I felt like I'd been freed. And oh, it was so, so nice.
The paradigm shifts didn't stop there, but it was a very long time before I truly found my footing with unschooling. In the early days it was mostly about learning without a curriculum. And that alone, when you consider how tightly the educational institution is woven within the fabric of our society, is quite radical.
Re-establishing myself within the context of community was enough of a challenge to last me a few solid years. I practiced my defense of unschooling. I wrote and refined my elevator speech. I fidgeted about misrepresenting ourselves as I fussed over what looked like learning and what didn't, and tried to soothe the naysayer that lived within my own head. I read as much as I could. I went on the prowl for other homeschoolers and unschoolers. I carefully micromanaged every interface with mainstream people and only let my guard down when in like-minded company.
And all the while, the kids played. And learned. And questioned. And stretched. And became fascinatingly complex people in their own right. Without school.
For then, it was enough. It was the beginning of a mass self-overhaul; a journey into the joyous unknown. Curiously, I was never scared. I didn't worry about the powers-that-be finding out and reporting us. I didn't worry that my kids would 'turn out' badly. I didn't worry that I'd perhaps chosen something too risky. I knew I was on the right path, even if it meant a few acrobatic feats were required along the way.
When you're truly home, you feel it in the deepest part of you.
Coming soon - When it became clear that unschooling was about far, FAR more than "no curriculum"
Next post - How Did We Get Here? Pt II --->


text:
NEW YORK (Reuters) - T-Mobile US Inc, the No. 4 U.S. wireless service provider, plans to stop carrying BlackBerry Ltd smartphones in its stores and instead ship the devices directly, according to an executive for the company.
David Carey, executive vice president for corporate services told Reuters about the plan on Wednesday, a few days after BlackBerry said it would no longer market to consumers because of drastically weakening smartphone sales.
Carey said that "keeping stock in the retail distribution system was inefficient" because BlackBerry phones have not been high demand devices for consumers.
He said BlackBerry smartphones are mostly purchased by businesses who do not make buying decisions in stores.
"Therefore we will display and sell it in the store for those consumers who would like to see one," he added.
Reporting by Sinead Carew. Editing by Andre Grenon


text:
If the rapper T.I. ever gets tired of the fame and popularity created by his nimble wordplay and smooth flow, he may have a second career already lined up: crisis negotiator.
The hip-hop star is being credited with saving a suicidal man's life after hearing a radio report about a person threatening to jump off a building, reports the Atlanta Journal Constitution.
Upon hearing the news, T.I. drove to the office building in downtown Atlanta and offered his assistance to the police.
"Something in me just said, 'Man, you gotta try and help. You gotta do whatever you can," T.I. said.
An officer on the scene shot a quick video of the rap star, which was then sent to the man on the roof.
"He came to the scene and offered to talk to him, we told the young man that, and he came down," said Officer James Polite of the Atlanta police.
In the clip, the rapper, whose real name is Clifford Harris, pleaded with the jumper to reconsider his decision.
"Nothing is that bad," the self-proclaimed King of the South said. "Nothing in life is worth taking your life. I'm here to help you. Please come down and talk to me."
The man, whose name was not released, eventually climbed down, spoke with the rapper, and was then transported to a hospital for treatment. He will not face changes.
Polite said that the police were thankful for T.I.'s assistance.
"He didn't have to stop. He couldn't kept on going about his business," he said. "We're happy it ended the way it did, and we thank him."
T.I. has had his own problems with the law, including a jail stint on a gun possession charge, but he may have earned himself some good will with his heroic act.


text:
While catching up on reading blogs I came across this blog by Amy Johnson Crow's: No Story Too Small
She's set a challenge: 52 Ancestors in 52 Weeks.
challenge: have one blog post each week devoted to a specific ancestor.
It could be a story, a biography, a photograph, an outline of a
research problem — anything that focuses on one ancestor.
So, I signed up. What better way to meet a couple of my goals including writing blogs consistently and writing mini-bios of my ancestors?
Now the decisions: What day of the week am I going to post? Which ancestor and/or family do I start with? Should I include my husband's family also? Will I need to include collateral lines to find 52?


text:
Donald Sterling's apology to CNN's Anderson Cooper backfired. But he could have learned a lesson from these corporate leaders.
Investing in the next big thing? Saving every cent? People in Times Square sound off on their best strategies to get rich.
He makes millions on and off the court. But his early Mother's Day gift? Priceless. Why sponsors are flocking to Kevin Durant.
From getting financing to negotiating, New Yorkers give their two cents on the tricky world of buying a home.
Financial planners say that you should put your money in the market to save for the future?but many people would rather keep it under their mattress.
People on the streets of New York offer their best advice for shedding some of those pre-job interview jitters.
These days, a used car can be a real bargain. According to Kelly Blue Book, used Kia Optimas, Nissan Jutes and plug-ins like the Chevy Volt are winners.
Your own personal island? A whirlpool? A safe haven for your children? New Yorkers describe their 'dream home.'
You either love them or hate them, but employee performance reviews are common in most companies. We accidently ran into football star Leonard Marshall and he described for us his own performance review.
Figure out how much money you need to retire and then plan your investments accordingly. It's not exactly that simple, but that's the key to building your nest egg.
- Not your kids' tree house(01:54)
- Mets fan's T-shirts bring in six-figures(3:22)
- China's growth hits 3-year low(2:48)
- French buy up NYC real estate(2:50)
- JPMorgan cleans up 'London whale' mess(2:04)
- Why unemployment is worse than it looks(2:25)
- $1.6 million RV with two bedrooms(2:28)
- DuPont CEO: Farm jobs are stable(4:22)
- How the Avanti redefined auto design(2:38)
- Airlines: 1M jobs in next 20 years(1:55)
- Scion iQ: Lousy car, but cute(1:57)
- $3.5M water tower home in the sky(1:55)
- Pawn your Picasso, fund your biz(2:19)
- $199 Nexus 7 costs Google $184 to make(2:12)
- Olympians struggle to pay their bills(2:29)
- Business News
- Markets
- Personal Finance
- Technology
- Luxury
- Small Business
- Fortune
- Money


text:
Smile Makeover before and after, frontal
Patient Info
Procedure: Smile Makeover
Procedure Description:
Smile Makeover involving a combination of veneers, implants, crowns and bridge work.
* All patients are unique and individual results may vary.
Cosmetic, General & Biomimetic Dentist
- Dr. Marc E. Lazare, DDS
- Physician
- View profile page
- 115 East 61st Street #14A, New York, NY, 10065
- 646-846-2465


text:
Athletes worldwide have agreed to the standards set forth in the World Anti-Doping Code. The Code defines the rights and responsibilities of all stakeholders in anti-doping.
As a signatory to the WADA Code, IRONMAN is responsible for the results management and adjudication for athletes and athlete support personnel participating in IRONMAN events and all athletes tested under its jurisdiction.
IRONMAN offers all athletes a right to appeal any charge under the IRONMAN Anti-Doping Rules through an independent arbitration process administered by McLaren Global Sports Solutions (MGSS). MGSS established and maintains a list of Arbitrators selected by MGSS for the IRONMAN Arbitration Panel. Members of the international panel are or have been Court of Arbitration for Sport arbitrators and have expertise in anti-doping; Richard McLaren serves as the panel's Chief Arbitrator. All decisions are solely at the discretion of the hearing panel and will be published and binding to IRONMAN.
Following the conclusion of results management proceedings conducted under IRONMAN's jurisdiction and in accordance with the IRONMAN Anti-Doping Rules and WADA Code, IRONMAN will publish the outcome, making public the name(s) of any individual sanctioned.


text:
- Communications and Marketing Campaigns
- Cultural Competence in the health sector
- Language Services
- NSW Multicultural Health Communication Service Website Information
- Services and Multicultural Organisations
- Translations
Communications and Marketing Campaigns
- Are there services that offer help in developing campaigns/strategies to target culturally and linguistically diverse communities in NSW?
Cultural Competence in the health sector
- What are the key components of a culturally competent health service?
The following frameworks and plans may be of help:
National Health and Medical Research Council
- Queensland Health
- Victoria Health
- South Australia Health
Language Services
- Where can I find an Interpreter in NSW?
If you are accessing a NSW Health service there are health care interpreter services available in Local Health Districts. Their contact numbers are available in the following publication: Multicultural Health Directory
Alternatively you may contact the Translating & Interpreting Service (TIS) on 131 450. The Australian Government, through the Department of Immigration and Citizenship, provides TIS for people who do not speak English and for English speakers needing to communicate with them.
TIS is Australia's only national service, and is available to any person or organisation in Australia requiring interpreting services. TIS is available 24 hours a day, 7 days a week, and is accessible from anywhere in Australia for the cost of a local call.
- Can I ask for an Interpreter in hospital?
Yes. According to the 'NSW Health Circular Standard Procedures for the Use of Health Care Interpreters' (94/10) all clients of non-English speaking background should be informed about the Health Care Interpreter Service (HCIS) and their ability to access a professional health care interpreter.
NSW Multicultural Health Communication Service Website Information
- Can I reproduce resources/publications on the website?
Permission is required in order to reproduce any resources/publications on the website. Please contact the service for further information: firstname.lastname@example.com
Services and Multicultural Organisations
- What health services are available for culturally diverse communities in NSW?
The Multicultural Health Directory provides details of services and programs for culturally diverse communities in NSW.
- What are the peak organisations for multicultural communities in NSW?
A listing of peak organisations for multicultural communities in NSW is provided by the Community Relations Commission.
- Is there a directory of multicultural health services?
Yes. The Multicultural Health Directory provides details of services and programs for culturally diverse communities in NSW.
- Where can I get information on issues to do with immigration and visas?
Contact the Department of Immigration and Citizenship.
- Where can I get information about Medicare eligibility?
Call Translating and Interpreting Service National on 131 450 about Medicare. You can also visit one of their Service Centres that offer free interpreters and document translations for Human Services business.
- Where can I get information about government financial assistance and help finding work?
Visit the Centrelink website
- Where can I go to have resources translated?
Please contact our Translations Manager for more information: 9816 0309
- Is there a guide to help me with translations? What makes a good translation?
The NSW Multicultural Health Communication Service has developed Translation Guidelines to assist with developing and checking translations.
- Where can I find free translated information?
For translated health information by subject category browse our site.
- Where can I find links to other websites containing translated information?
- which Chinese language should I select?
Mandarin and Cantonese are spoken languages, while Simplified and Traditional Chinese Characters are written languages.
Mandarin is the official language of the People's Republic of China (PRC) and the Republic of China (ROC, also known as Taiwan), as well as one of four official languages of Singapore. Cantonese is one of the official languages of Hong Kong (together with English) and of Macau (together with Portuguese) and also widely used by people from Southern China (mainly from Guang Dong Province).
There are currently two systems for Chinese characters: Traditional Chinese character system and Simplified Chinese character system. The Traditional Chinese character is used in Hong Kong, Taiwan, Macau and Chinese speaking communities (except Singapore and Malaysia) outside mainland China. The Simplified Chinese character is used in Mainland China and Singapore and Malaysia.
Here are some examples:
Spoken Language
Written Language
Mainland China
Mandarin or Cantonese
Simplified Chinese
Hong Kong and Macau
Traditional Chinese
Traditional Chinese
Simplified Chinese


text:
A common misconception among people who know very little about golf is that golfers are, by and large, kind of soft. They don't run around at high speeds, they don't tackle one another, they don't dive for line drives, they don't drive to the hoop. They walk around in the sunshine — and occasionally in the rain — and smack a little white ball for a few hours. Right?
In light of that fairly significant misapprehension, it's worth recalling that one of the sport's genuine legends, Ben "The Hawk" Hogan, is remembered not only for the jaw-dropping beauty of his game, but for a toughness that would have done Chuck Bednarik proud.
In early 1949, when he was 36 years old and already firmly established as one of the true greats, Hogan and his wife, Valerie, were involved in a hellish head-on collision with a Greyhound bus in Texas. Hogan reportedly hurled himself sideways before impact in order to protect his wife — and likely saved his own life, as well: the steering column was driven through the driver's seat.
The damage Hogan suffered was awful: a fractured pelvis, collar bone and ankle; a chipped rib; life-threatening blood clots. He was in the hospital for months, and doctors feared he might never walk again. A return to competitive golf, meanwhile, was not even an option.
Or rather, it wouldn't have been an option for most people.
But less than a year later, Hogan not only returned to golf, playing the Los Angeles Open to start the PGA Tour in January 1950, but tied fellow legend San Snead over 72 holes, finally losing in a playoff. Six months later, Hogan won the U.S. Open at Merion in Pennsylvania, marking one of the most extraordinary, inspiring and downright tough comebacks in the history of American sport.
Here, as the 2013 U.S. Open gets underway — once again at Merion in Ardmore, Pa. — LIFE.com pays tribute to Hogan's astonishing return to the links with a series of photos, most of which never ran in LIFE, made by Peter Stackpole at the Riviera Country Club in January 1950.
Below: Exhausted but unbowed, Ben Hogan faces reporters during his return to the PGA Tour in the Los Angeles Open, January 1950.


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Stone Creek Ranch in Delray Beach offers a majestic lifestyle of comfort and tranquility just steps from it all. This private gated community hosts multi-million dollar properties in a beautiful setting, making it one of the most desirable places to call home in all of South Florida.
Real Estate: At Stone Creek Ranch, mega mansions reside on acreage estate size lots, most providing panoramic lake views. Stone Creek Ranch luxury real estate features spellbinding estates situated on expansive lots, some of which are located along the water. Residents and guests of Stone Creek Ranch enter through 24-hour manned gates to find striking custom-built estate homes surrounded by expansive blue lakes, grand landscaping and lush green vistas. Stone Creek Ranch was constructed on 187 acres of tropical landscaping by some of the finest builders in Florida. The square-footage of the opulent estate properties in Stone Creek Ranch range from 6,500 to over 14,000 square feet while offering water views from all vantage points.
Lifestyle: Stone Creek Ranch is situated between Palm Beach and Boca Raton, providing easy access to some of the area's best shopping, superior restaurants, nightlife, cultural attractions and more. Pristine golf courses and country clubs are scattered all around Stone Creek Ranch, including Saint Andrews Country Club, Mizner Country Club, Royal Palm Yacht & Country Club, Boca Resort and Beach Club, and more. This is an ideal residence for the golfer, socialite and those who maintain a luxurious lifestyle.
Education: Stone Creek Ranch is located near several area public schools, including Sunrise Park Elementary School, Eagles Landing Middle School and Olympic Heights Community High School. Nearby private schools include Spanish River Christian School and St. Andrews School.
Water Access: While Stone Creek Ranch is considered a more inland community, residents may access the white sand beaches of the Atlantic with a short drive. However, their private pools and spas provide a peaceful setting for sunbathing and swimming at home.


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-AltairAnyway, I've found that some of the objections in the 'flat earth' videos are quite real
Several explanations have been offered for the fact that the wires supposed to hang parallel to each other were farther apart 4,250 feet below the surface than they were at the surface, but no one has suggested anything that seems to cover the question. It seems to be the general opinion that attraction or repulsion somewhere accounts for the phenomenon, but where it is, and why it should be no one knows. Were there no disturbing forces at work there should be a slight convergence
Atmospheric refraction is the deviation of light or other electromagnetic wave from a straight line as it passes through the atmosphere due to the variation in air density as a function of height.[1] This refraction is due to the velocity of light through air, decreasing (the refractive index increases) with increased density. Atmospheric refraction near the ground produces mirages. Such refraction can also raise or lower, or stretch or shorten, the images of distant objects without involving mirages.
Return to Apollo, and more space hoaxes
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BA2107 Mixed Color Tiger's Eye Natural Crystal Stretch Bracelet
Tigers eye is a favourite when it comes to protective stones. Much like with the Tibetan dzi beads, the watchful eye energy of the tigers stone has long been used in various forms of jewelry and protective home decor. Tigers eye can also help balance and clear emotions, thus contributing to a calm mind and peaceful disposition.


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Friday, August 8, 2014
The Playsuit
Welcome back everyone! I hope you're all enjoying your summer holidays in the best possible way: going to the beach, hanging out with all your friends, partying, catching up with the TV shows you couldn't keep up with during the school year and also just doing nothing, enjoying the freedom!
I'm now back from my 3 week stay in the beautiful city of Chicago!! This trip could not have been more amazing! The city had the perfect combination between an urban up-beat lifestyle, but also a more relaxed one because only 2 minutes away from the busy Michigan Ave. (kind of like the 5th Ave. of Chicago) you had lake side beaches and calmer neighbourhoods.
All in all, it was for sure one of the best holidays of my life. Having family there also made it that much more enjoyable and fun! I hope you all liked this easy, laid-back look with a little Givenchy treasure stolen from the Mother's wardrobe :)
Friday, July 25, 2014
Chicago Streets
Hello hello from beautiful Chicago! As promised here is my first outfit post while I'm here. My days have been spent in the best way possible; exploring a new amazing city, spending time with family and friends, trying new restaurants... basically some essential ingredients to a great summer holiday!
I couldn't be happier with my stay here, its just too bad that time flies by so quickly, the trick really is to just make the most of it.
I hope you liked the first look and do leave me your suggestions below of places I definitely have to visit!
Monday, July 14, 2014
Festival Attire
NOS ALIVE 2014! As you're reading this post, I'm already in the beautiful city of Chicago!! I'm so thrilled to be here but I wanted to quickly share with you one of the looks I wore to 'Nos Alive'- an amazing musical festival that took place for three consecutive days in Lisbon. Check out their website HERE to see how great the lineup was!
For festival occasions its always important to be comfortable and wear appropriate footwear so you're free to jump, run around and enjoy every moment possible! This day I chose my new Adidas trainers from HOODBOYZ store because I love the casual and sporty style that they add to this outfit.
Keep checking in for some Chicago looks, I can't wait to explore this city!
Saturday, July 12, 2014
Palais Royal
PALAIS ROYAL. A place I've always wanted to shoot in! Unfortunately there was construction working happening around but that didn't stop us from snapping some pictures. You may now be wondering what this little blue statue is... By chance the artist who made these was there with his photographer to shoot a his brand new campaign. We got to talking and he showed interest in having me pose with his pieces to use as part of his new campaign! The result was an improvised photoshoot right in the heart of Paris! It was so much fun, specially because it was so unexpected!
Following on in the list of surprises, here is my first look with one of my new big purchases; the Givenchy Antigona bag!! As you must know by now bags and sunglasses are my favorite accessories, I'm absolutely crazy about them. This one came because of a special reason, my 18th birthday present. My birthday was all the way back in April but as I knew I was going to Paris in June I told my parents I would rather wait and get something I really wanted while I was there.
Lastly, I had to share the news that I'm off to Chicago tomorrow morning... as you may be able to guess, excitement levels are high! I'll be staying there for 3 weeks so expect many posts and pictures coming your way. Remember to always keep updated through my instagram @luizagrinberg where I'll be posting my daily adventures.
Shirt: ZARA
Shorts: ZARA
Blazer: ZARA
Shoes: LE LIS BLANC
Bag: GIVENCHY
Watch: MARC JACOBS
Wednesday, July 9, 2014
Pont des Arts
PONT DES ARTS. Beautiful and romantic as ever! As I was traveling with my best friend, we just had to give in and put our names on a lock and dramatically throw away the key into the river Seine (very movie-like I have to admit!) For sure a moment to treasure forever!
Keep updated for the last Paris look that is still to come with a special surprise in it!
Sunday, June 29, 2014
From Paris With Love
JARDIN DES TUILERIES. What a beautiful, magical place. If I lived in Paris this one definitely be one of the places I would be spending a great portion of my time in. Its amazing how in Paris everywhere you look is almost like a living painting... beauty everywhere!
Hope you liked these pictures, they're some of my favorites!
Also, don't forget to check out and like some of my most recent looks on the Teen Vogue Fashion Click! Links to it HERE and HERE :)
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Everton have had their noses bloodied by lesser mortals in recent weeks so were grateful for the arrival of the Premier League's worst travellers to maintain their pursuit of Champions League football. A routine victory kept them within six points of the top four but a deep cut to their captain Phil Jagielka's ankle left them fretting after the final whistle.
Two minutes had passed in what turned out to be Everton's second league win since 2 January, when Reading striker Adam Le Fondre's over-zealous challenge felled the England defender. Jagielka was unable to continue and, according to David Moyes departed the ground in need of a hospital visit. "Jags is going to get surgery on his ankle to stitch it up. It's a bad, bad gash," the Everton manager said. "I don't mind robust challenges but I do mind one that puts out one of my best players. He might be out for a couple of weeks."
Brian McDermott absolved his player of blame. "Adam is not that type of player, he's a very honest player," the Reading manager said. "There is no way that Adam is a player that would 'do' anybody."
Having relinquished a winning position in the dying embers of the previous week's match at Norwich and also unexpectedly dropped points at home to relegation-threatened Aston Villa this year, it appeared the latest in a catalogue of setbacks might further disrupt Everton. They were already without the goalkeeper Tim Howard, whose jarred back in the FA Cup replay victory over Oldham terminated a sequence of 210 consecutive league appearances, three shy of Neville Southall's club record.
It meant a league debut for the Slovakia international Jan Mucha almost three years since his arrival from Legia Warsaw. But aAfter shaking off their early lethargy, Everton ensured it was Reading's Stuart Taylor who was the busier of the two goalkeepers. An ankle sprain in training on Friday ruled out Adam Federici and presented the perennial No2 Taylor with his 69th appearance in league football since signing professional forms with Arsenal in the summer of 1997. The 32-year-old's previous one had come in April 2009 for Cardiff at Preston. Ominously, he had been on the wrong end of a 6-0 scoreline.
However, Taylor acquitted himself admirably until the returning Belgian midfielder Marouane Fellaini's unruly barnet brought order to the contest by connecting with Seamus Coleman's inviting right-wing cross three minutes before the break. Only Taylor's fingertips kept out Fellaini's audacious volley from the most acute of angles in first-half injury time.
"He has got a lot of really good attributes, he can get better but he has an awful lot going for him and on his day he can be a handful," Moyes said.
Perhaps preoccupied with Fellaini's burst forward, Reading backed off Steven Pienaar on the hour with calamitous consequences, as a searing drive left Taylor helpless. By the midpoint of the second period it was game over as another Belgian, Kevin Mirallas, seized on Pienaar's pass, flashed his eyes one way and sent the ball the other to beat Taylor at his near post.
To their credit, Reading, who had struck the upright through Le Fondre with the scoreline goalless, refused to throw in the towel, and were rewarded when the substitute Hal Robson-Kanu nodded in an Ian Harte centre slung in from the left six minutes from time.
Even harder away fixtures are on the horizon for the Premier League new boys, with trips to Manchester United and Arsenal up next, but McDermott believes memories of last year's promotion campaign allied to their togetherness can inspire a successful survival fight. "We have finished the last three seasons very strongly and if we can do the same again it will give us a real chance. There's nothing in it if you look at it," he said.


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If banks such as Barclays had not tried to manipulate lending rates during the 2008 financial crisis, the panic around the financial system might have been worse.
That, at least, is the thinking behind those who believe the scandal behind crisis-era rates for Libor — the London Interbank Offered Rate—probably won't produce criminal prosecutions.
Those on the other side of the argument, though, say the Libor scandal is a big deal and the factors that led to it still haven't been addressed.
Dick Bove, the widely followed banking analyst at Rochdale Securities, is one who believes that while there is plenty of evidence to suggest that Barclaysand others lied about rates, and that regulators even were aware that it was going on, the regulators probably acted properly in not making more of it at the time.
Bove acknowledged holding what "may be a contradictory stance," but he is sticking to it.
"It will be recalled that the regulators were dealing with a significant financial crisis. To stem the panic, they lowered interest rates, invested in banks, loaned trillions of dollars to these institutions and guaranteed trillions more in bank liabilities," he said in an analysis for clients.
"If the dollar Libor rate had risen sharply in this period all of this activity would not have succeeded."
Setting Libor is a complicated process, and the role it played in the financial crisis is no less so.
Libor is set each night when leading banks estimate the rates they would be charged when borrowing from each other. The concept is important because it reflects the risk that each institution applies to its financial position. Overnight borrowing is a key part of the large banks' business models to fund operations.
Barclays admitted to fudging its Libor numbers during the crisis because, according to transcripts the Federal Reserve released last week, it feared that a true rate reflecting its credit risk might cause concern among investors and impact its stock price.
Bove said an artificially low Libor also may have helped prevent further global tumult "because it is the dollar Libor rate, and not the Federal Funds rate, that is used to determine the interest rates charged on the bulk of the loans in the United States, and financial securities around the globe.
"If this rate had jumped precipitously in late 2008, the 'tax' on the United States economy would have been enormous. Households and businesses would have been forced to increase their payments on virtually all of their debt by very sizable amounts."
But was it really a case of no harm-no foul?
Kevin Ferry, who runs Cronus Futures Management in Chicago, doesn't think so.
"They'll sat it's counterfactual, but it's the core of the argument. They're trying to get PR language out there saying the rates were down, so who was hurt by it?," Ferry says. Answering the question, he offers: "Anyone who was anticipating higher rates."
That's no small consideration, with hundreds of trillions, notionally, in derivatives floating around the marketplace and dependent on accurate rate-setting.
From traders in the futures pits to governments hedging against their credit exposure, there were plenty of victims of Libor cheatingwho no doubt would like to see someone get some comeuppance. (For the record, Ferry had taken out futures contracts anticipating lower rates, so he was not individually harmed.)
Lots of traders try to make money off the rate differences, particularly the "Ted Spread," which is the difference between three-month Treasury yields and eurodollar contracts of the same expiration. Wider spreads indicate greater financial stress.
"The Fed harmed you because their facilities, policies and public statements were designed to drive that spread in on you," Ferry says. "You're materially harmed if you're long the Ted."
Like many others, Ferry says Libor manipulation was an open secret at the time, and talk of investigations has been around the markets for years. Regulators at the New York Federal Reserve, headed then by current Treasury Secretary Timothy Geithner, have said they were on top of the matter during the crisis.
Geithner reiterated as much during the "Delivering Alpha" conference presented Wednesday by CNBC and Institutional Investor magazine.
"I know they were on top of it because I was talking to people during the crisis. 'We know this, Kevin,' is what they said," Ferry says. He adds: "As those spreads move out, the ability of the system to fund itself becomes more expensive. It seizes up. So there's no conspiracy in the Treasury Department or the Fed to do what they did. They wanted that to happen."
The one point that both sides in the discussion agree on is that the system needs to be changed, which may be the one great result of the scandal.
"They wonder why the economy doesn't come back, they wonder why the financial system isn't doing anything," Ferry says. "It's the Karen Ann Quinlan of financial systems. It's being kept alive while they develop the processes that will constitute the new financial system. They don't want banks to fund themselves this way anymore."
Bove objects to the near-exclusion of U.S. banks in setting the lending rate, with only three American institutions among the 18 surveyed.
"It should be controlled by Americans, and it should be flexible enough to allow central bankers to intervene in times of crisis," he says. "These are the issues that should be under discussion now, not baiting the banks one more time. It is time that this society realizes that it must understand the banking industry and how it interacts with the economy rather than dissolving into meaningless hyperbole again."
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FORT VALLEY – Kevin Burnell hit three three-pointers in overtime as Georgia Southwestern improved to 3-0 on the season with a 79-77 win at Fort Valley State on Tuesday. The Hurricanes got 33 points from their bench players in the game and held the Wildcats to 36 percent shooting on the night.
The game was tied at 58 with 5:59 to play following a layup from Alan Arnett. GSW then took the lead on a Daryl Davis layup but lost it as FVSU went on a 7-2 run capped by a Brandon Davey layup with 3:33 to play.
Davis led all players with 26 points for the Wildcats while Davey added a monster line of 23 points and 17 rebounds in the loss.
The Hurricanes look to keep their season-opening unbeaten streak alive on Thursday when they host West Florida in the Storm Dome at 7:30 p.m.


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This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.
Note: Separate PDQ summaries on Oral Cancer Prevention and Lip and Oral Cavity Cancer Treatment are also available.
There is inadequate evidence to establish whether screening would result in a decrease in mortality from oral cancer.
Magnitude of Effect: No evidence of benefit or harm.
Harms have not been systematically studied and cannot be quantified based upon the literature. However, there are some unavoidable harms that would be associated with routine screening, including:
Magnitude of Effect: Unknown.
Incidence and mortality
An estimated 40, 250 new cases of oral cancer will be diagnosed in the United States in 2012, and an estimated 7,850 people will die of the disease.[1] This form of cancer accounts for about 3% of cancers in men[1] and 1.5% of cancers in women.[2] Oral cancer occurs more frequently in blacks than in whites.[3,4] The overall annual incidence in the United States is about 10.4 per 100,000 men and women; the median age at diagnosis of oral cavity or pharyngeal cancer was 62 years from 2003 to 2007.[4]
Incidence has been falling in men since 1975 and in women since 1980. However, incidence has recently been increasing for oral cancers related to human papillomavirus (HPV) infection.[1] About 60% of oral/pharyngeal cancers are moderately advanced (regional stage) or metastatic at the time of diagnosis.[4]
The estimated annual worldwide number of incident oral cancers is about 275,000, with an approximately 20-fold variation geographically.[5] South and Southeast Asia (India, Sri Lanka, Pakistan, and Bangladesh), France, and Brazil have particularly high rates. In most countries, men have higher rates of oral cancer than women (due to tobacco use) and higher rates of lip cancer (due to sunlight exposure from outdoor occupations).[5]
Risk factors
The primary risk factors for oral cancer in American men and women are tobacco (including smokeless tobacco) and alcohol use. Infection with HPV-16 has been associated with an excess risk of developing squamous cell carcinoma of the oropharynx.[6]
Evidence of Benefit Associated With Screening
No population-based screening programs for oral cancers have been implemented in developed countries, although opportunistic screening or screening as part of a periodic health examination has been advocated.[7,8] There are different methods of screening for oral cancers. Oral cancer occurs in a region of the body that is generally accessible to physical examination by the patient, the dentist, and the physician; and visual examination is the most common method used to detect visible lesions. Other methods have been used to augment clinical detection of oral lesions and include toluidine blue, brush biopsy, and fluorescence staining.
An inspection of the oral cavity is often part of a physical examination in a dentist's or physician's office. It has been pointed out that high-risk individuals visit their medical doctors more frequently than they visit their dentists. Although physicians are more likely to provide risk-factor counseling (such as tobacco cessation), they are less likely than dentists to perform an oral cancer examination.[9] Overall, only a fraction (~20%) of Americans receive an oral cancer examination. Black patients, Hispanic patients, and those who have a lower level of education are less likely to have such an examination, perhaps because they lack access to medical care.[9] An oral examination often includes looking for leukoplakia and erythroplakia lesions, which can progress to cancer.[10,11] One study has shown that direct fluorescence visualization (using a simple hand-held device in the operating room) could identify subclinical high-risk fields with cancerous or precancerous changes extending up to 25 mm beyond the primary tumor in 19 of 20 patients undergoing oral surgery for invasive or in situ squamous cell tumors.[12] However, this finding has not yet been tested in a screening setting. Data suggest that molecular markers may be useful in the prognosis of these premalignant oral lesions.[13]
The routine examination of asymptomatic and symptomatic patients can lead to detection of earlier stage cancers and premalignant lesions. There is no definitive evidence, however, to show that this screening can reduce oral cancer mortality, and there are no randomized controlled trials (RCT) in any Western or other low-risk populations.[11,14,15,16,17]
In a single RCT of screening versus usual care, 13 geographic clusters in the Trivandrum district of Kerala, India, were randomly assigned to receive systematic oral visual screening by trained health workers (seven screened clusters, six control clusters) every 3 years for three screening rounds during the period of 1996 to 2004.[18,19,20] Cluster size varied from 5,177 to 12,147 (mean 8,815) participants. The number of interviewed (and analyzed) participants in the screening and control clusters were 87,829 and 80,086, respectively. During the 9-year period of the clinical trial, there were 77 deaths from oral cancer in the screening arm and 87 in the control arm. The cause-specific mortality rates were 16.4 versus 20.7 per 100,000 person-years (relative risk [RR] = 0.79; 95% confidence interval [CI], 0.51–1.22). In a subset analysis restricted to tobacco or alcohol users, the cause-specific mortality rates were 29.9 versus 45.4 per 100,000 person-years (RR = 0.66; 95% CI, 0.45–0.95). In male tobacco or alcohol users, the RR was 0.57 (95% CI, 0.35–0.93) and in female users, the RR was 0.78 (95% CI, 0.43–1.42). There was a qualitative difference in screening effect for nonusers: 3.0 versus 0.9 per 100,000 person-years in the screened and control arms (RR = 3.47; 95% CI, 0.12–96.51). Although there was a higher number of early-stage (I and II) cases in the screened arm versus the control arm (85 vs. 37), the number of late-stage (III and IV) cancers was similar (104 vs. 105). Therefore, there was not a clear, true stage shift, even though the proportion of cases with early-stage disease was higher in the screened arm.
Aside from the issue of generalizability to other populations and from the overall lack of a statistically significant result in cause-specific mortality, serious methodologic problems make interpretation of the results difficult, including lack of detail about the randomization process, lack of allocation concealment, and lack of adjustment for clustering effect. The total number of clusters randomized was small, and there were different distributions of income and household possessions between the two study arms. Withdrawals and dropouts were not clearly described. In summary, the sole randomized trial does not provide solid evidence of a cause-specific mortality benefit associated with systematic oral cavity visual examination.
Adjunctive techniques to visual examination
Techniques such as toluidine blue staining, brush biopsy/cytology, or fluorescence imaging as the primary screening tool or as an adjunct for screening have not been shown to have superior sensitivity and specificity for visual examination alone or to yield better health outcomes.[11,21] In a RCT conducted in Keelung County, Taiwan, 7,975 individuals at high risk of oral cancer due to cigarette smoking or betel quid chewing were randomly assigned to receive a one-time oral cancer examination after gargling with toluidine blue or a blue placebo dye.[22] The positive test rates were 9.5% versus 8.3%, respectively, (P = .047). The detection of premalignant lesions was not statistically different (rate ratio = 1.05; 95% CI, 0.74–1.41). The number of overall oral cancers diagnosed within the short follow-up period of 5 years was too small for valid comparison (six in each group).
The operating characteristics of the various techniques used as an adjunct to oral visual examination are not well established. A systematic literature review of toluidine blue, a variety of other visualization adjuncts, and cytopathology in the screening setting revealed a very broad range of reported sensitivities, specificities, and positive predictive values when using biopsy confirmation as the gold standard outcome.[23] In part, this was due to varying study populations, sample size and settings, as well as criteria for positive-clinical examinations and for scoring a biopsy as positive.
Evidence of Harm Associated With Screening
Harms associated with screening for oral cancer are poorly studied in any quantifiable way.[17] However, there are some unavoidable harms that would be associated with routine screening, including:
An additional potential harm is misdiagnosis and resulting under- or over-treatment, given the subjective pathology judgments in reading biopsies of oral lesions. When 87 biopsy diagnoses of oral lesions were compared between 21 local pathologists and double-reading by two of three central pathologists in a multicenter study of patients with prior upper aerodigestive tract cancers, agreement was only fair-to-good (kappa weighted-statistic = 0.59; 95% CI, 0.45–0.72).[25] In a bivariate categorization of carcinoma in situ plus carcinoma versus less serious lesions, the agreement was poor, but with very wide CIs (kappa-statistic = 0.39; 95% CI, -0.12–0.97). The investigators in the same study analyzed an agreement between the local and central pathologists on clinically normal tissue adjacent to 67 biopsied clinically-suspicious lesions. The agreement on clinically normal tissue was better than for visibly abnormal lesions, but still not in the excellent range (kappa weighted-statistic = 0.75; 95% CI, 0.64–0.86).[26]
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Description of the Evidence
Updated statistics with estimated new cases and deaths for 2012 (cited American Cancer Society as reference 1).
If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.
Purpose of This Summary
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about oral cancer screening. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.
Reviewers and Updates
This summary is reviewed regularly and updated as necessary by the PDQ Screening and Prevention Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH).
Board members review recently published articles each month to determine whether an article should:
Changes to the summaries are made through a consensus process in which Board members evaluate the strength of the evidence in the published articles and determine how the article should be included in the summary.
Any comments or questions about the summary content should be submitted to Cancer.gov through the Web site's Contact Form. Do not contact the individual Board Members with questions or comments about the summaries. Board members will not respond to individual inquiries.
Levels of Evidence
Some of the reference citations in this summary are accompanied by a level-of-evidence designation. These designations are intended to help readers assess the strength of the evidence supporting the use of specific interventions or approaches. The PDQ Screening and Prevention Editorial Board uses a formal evidence ranking system in developing its level-of-evidence designations.
Permission to Use This Summary
PDQ is a registered trademark. Although the content of PDQ documents can be used freely as text, it cannot be identified as an NCI PDQ cancer information summary unless it is presented in its entirety and is regularly updated. However, an author would be permitted to write a sentence such as "NCI's PDQ cancer information summary about breast cancer prevention states the risks succinctly: [include excerpt from the summary]."
The preferred citation for this PDQ summary is:
National Cancer Institute: PDQ® Oral Cancer Screening. Bethesda, MD: National Cancer Institute. Date last modified <MM/DD/YYYY>. Available at: http://cancer.gov/cancertopics/pdq/screening/oral/HealthProfessional. Accessed <MM/DD/YYYY>.
Images in this summary are used with permission of the author(s), artist, and/or publisher for use within the PDQ summaries only. Permission to use images outside the context of PDQ information must be obtained from the owner(s) and cannot be granted by the National Cancer Institute. Information about using the illustrations in this summary, along with many other cancer-related images, is available in Visuals Online, a collection of over 2,000 scientific images.
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A 26 year-old British software developer has been ranked as the best civilian in the 2012 DC3 Digital Forensics Challenge, an unusually demanding round of the Cyber Security Challenge hosted by the US Department of Defense Cyber Crime Centre (DC3).
Chris Doman from Essex came second to a team of professionals from Northrop Grumman in the December event, but beat competition from 2,000 other competitors from 53 countries, making him the best non-pro in the world.
Doing well in the event meant conquering a series of scenario-based challenges, including communication and information recovery, data hiding, metadata hashing and file signatures.
"I looked through all 34 challenges and wrote a plan of how to do them all and how long it would take. It's all certainly possible to solve but it's not easy and you have to think carefully about the time required for each challenge," said Doman.
The Cyber Security Challenge has certainly reignited my love for cyber security and problem solving. I did better than I expected, and it's given me a boost to start applying for work in this field," he added.
Doman set up his own company, Ignite Research, in 2009, but had turned away from his interest in security after leaving school, he said.
His prize from the DC3 Digital Forensics Challenge is free admittance to one of training firm 7Safe's university-accredited ethical hacking courses.
He plans to take part in the next UK Cyber Security Challenge this month, the Sophos Malware Hunt, which will pit contestants against "the nastiest creations of both cyber-criminal gangs and nation states."
Two other UK non-security amateurs also finished in the top 12, IT professional Matt Bartlett and Durham University student Chris Moore. Both will participate in the Sophos Malware Hunt.
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Stephen Colbert wants you to do your part in preparing the Republican presidential candidates for the general election: Talk trash about them.
On "The Colbert Report" Wednesday night, the would-be conservative talk show host reacted to Mitt Romney's victory in Florida a day earlier — and his decisive margin.
"14 percent! That is higher than Mitt's tax rate," Colbert joked. "Romney kicked Newt to the curb like a plant manager whose job he just moved to another country."
He noted, though, that part of what helped secure Romney his Florida win was the nasty turn toward negativity his campaign has taken — with many pundits calling this race the most vicious in presidential history.
And mocking Romney's claim that the onslaught of negativity was helping to prepare Republicans for their fight against Obama, Colbert unveiled a new hashtag he wants his fans to use in mean-spirited tweets aimed at the frontrunners: #preparethem.
"Do the right thing, nation, and really tear these guys a new one to, you know, help," he said.
Check out the clip below.
The Colbert Report
Get More: Colbert Report Full Episodes,Political Humor & Satire Blog,Video Archive


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FaceTime Features on Your iPhone 4S
FaceTime, Apple's video calling feature, puts your iPhone 4S in a whole different class when it comes to making phone calls. Plus, FaceTime comes with at least two major benefits, besides the video (which is typically pretty good):
FaceTime calls don't count against your regular minutes.
The audio quality on FaceTime calls is superior to a regular cell phone connection.
When you're FaceTiming, you see the person you're chatting with, but you also see your own face in a small picture-in-picture (PiP) window, which you can drag to a corner of the screen:
The PiP image represents what the other person sees, so it's a good way of knowing, short of the other person telling you, if your face has dropped out of the frame. You can use FaceTime in portrait or landscape mode. You might find it easier to bring another person into a scene in landscape mode.
Although many FaceTime calls start with a regular AT&T, Sprint, Verizon, or C Spire call, you can't go from FaceTime to an audio-only call without hanging up and redialing. Similarly, if you drop a FaceTime call because of a Wi-Fi hiccup or some other problem, you'll have to redial via FaceTime or your provider, depending on whether you want the call to be video or only audio.
You have choices in how (and whether) to handle a FaceTime call and what you can do while on a call:
Block all FaceTime calls: If you just don't feel up to being seen while talking, tap Settings from the Home screen, tap Phone, and make sure FaceTime is off. If you can't find the FaceTime button or wonder why you're not getting FaceTime calls, go back into Settings and make sure this option is turned on. Although you are in FaceTime Settings, you'll notice that you can list one or more e-mail addresses by which a caller can reach you for a video call, along with your iPhone's phone number.
Decline FaceTime: Cool as it can be to see and be seen, ask yourself if you really want to be seen, say, when you just got out of bed. If you don't, just decline the FaceTime aspect of the call.
Mute the audio: Tap the microphone icon with the slash running through it. The caller can continue to see you but not hear you.
Check out another iPhone app while on a FaceTime call: Simply press the Home button and then tap the icon for the app you have in mind. At this point, you can still talk over FaceTime, but you'll no longer see the person. Tap the green bar at the top of the screen to bring the person back in front of you.
Toggle between the front and rear cameras on your iPhone 4S: Apple says the front camera has been fine-tuned for FaceTime usage, which in photography-speak means the camera has the proper field of view and focal length. But at times, you'll want to use the iPhone's main camera on the rear to best show off your surroundings and give the caller an idea of where you are. To toggle between the front and main cameras, tap the icon at the bottom-right corner of the screen.


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Compilation and Review of Financial Statements
1. This statement defines the compilation of financial statements and the review of financial statements of a nonpublic entity and pro-vides guidance to accountants concerning the standards and pro-cedures applicable to such engagements.1 The accountant is required to issue a report whenever he completes a compilation or review of the financial statements of a nonpublic entity in com-pliance with the provisions of this statement. The accountant should not issue any report on the unaudited financial statements of a nonpublic entity or submit such financial statements to his client or others unless he complies with the provisions of this statement.
2. The statement recognizes that accountants may perform other accounting services either in connection with the compilation or review of financial statements or as a separate service. The state-ment distinguishes such services from a compilation and from a review. The statement does not establish standards or procedures for such other accounting services, examples of which follow:
a. Preparing a working trial balance.
b. Assisting in adjusting the books of account.
c. Consulting on accounting, tax, and similar matters.
d. Preparing tax returns.
e. Providing various manual or automated bookkeeping or data processing services unless the output is in the form of financial statements.
f. Processing financial data for clients of other accounting firms.
1. Statements on auditing standards provide guidance to the accountant who performs services in connection with the unaudited financial statements of a public entity.
Copyright © 1979 by the
American Institute of Certified Public Accountants, Inc. 1211 Avenue of the Americas, New York, N.Y. 10036
Statement on Standards for Accounting and Review Services
Issued by the Accounting and Review Sen/ices Committee
American Institute of Certified Public Accountants
December 1978


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Mobile BankingLearn more ▶
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When it comes to commercial banking, more and more Texans are turning to First Financial. Since 1890, we've been meeting the financial needs of both large and small businesses. Whether you're doing business around the corner or around the globe, we can provide the customized solutions and services your business needs to prosper.
Today's business environment is constantly changing. To thrive means not only tackling today's challenges, but also planning for the future. From business checking accounts, to loans, to investment options, we have the products and services to help you meet those needs.
At First Financial, we're committed to putting you and your business first with personal attention each and every day. Of course, we're also highly committed to the community. After all, we live here too. We believe growing the community starts with growing businesses.
Discover for yourself how our expertise can help your business succeed and grow. Whether you're building a business from the ground up or have one that's already established, we're here to help you make better banking decisions.
Start your business relationship with First Financial today and discover how we put You First.
There's a lot to know about running a business. We've been helping businesses for over 124 years, so we know how to get one started and keep it growing.Click here to learn more about starting and growing your business.
A checking account is an integral part of every business. First Financial has a variety of accounts that are just right for your needs.Click here to learn about checking and savings.
The success of your business depends on having the right financial resources. With a full line of business loan products, we can provide the capital needed to run your business smoothly.Click here to learn about business lending.
Managing cash flow is critical to maintaining the financial health of your company. We can help you with everything from receivables to payments and payroll.Click here to learn about business banking services.
The website terms, privacy, and security policies for First Financial Bank N.A. do not apply to the site you are about to visit:
Please review the website terms, privacy, and security policies for the aforementioned site to see how they apply to you.


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MuscleTech Nitrotech Performance Series - 907g
Fast and free delivery from €200
Recommended: combine it with...
Characteristics MuscleTech Nitrotech Performance Series - 907g
- Whey isolate & peptides as primary source
- Builds 70% more lean muscle than regular whey
- Superior whey protein formula
- Amplifies recovery, performance & strength
Nitro-Tech Fuels The Pros
Very few proteins completely change the game, and for years bodybuilders were given very few options for protein sources that were scientifically formulated to help build more muscle. As a result, for years you could basically change protein brands every month and see no difference in gains at all.
This changed with the launch of Nitro-Tech®. MuscleTech® researchers invested countless hours working to create a protein formula that packs on more muscle and builds more strength than regular whey protein. With the powerful Nitro-Tech® formula, they succeeded and now bodybuilders and other athletes have an advanced whey protein supplement that actually delivers superior musclebuilding results!
Nitro-Tech® is a scientifically engineered, enhanced whey protein formula designed for all athletes who are looking for more muscle, more strength and better performance. Nitro-Tech® contains protein sourced primarily from whey protein isolate and whey peptides – two of the cleanest and purest protein sources available. Other whey protein supplements might have only a few grams of these highly bioavailable and easily digested proteins. Nitro-Tech® is also enhanced with the most studied form of creatine for even better gains in muscle and strength.
Each scoop of Nitro-Tech® contains 30 grams of protein, primarily from whey protein isolate and whey peptides. These have several advantages over other forms of protein.
- Delivers Ultraclean Whey Isolate and Peptides
Supplying 30 full grams of the most quickly absorbable and highest biological value proteins available. These are two of the cleanest sources of protein available to athletes.
- Contains a Clinically Proven Dose of Pure Creatine Monohydrate
Each scoop supplies a full 3-gram dose of the most researched form of creatine available – creatine monohydrate. Creatine in combination with whey protein has been clinically shown in a published study to be more effective for building muscle than whey protein on its own.
- Provides All Essential Amino Acids
The protein in Nitro-Tech® provides a complete amino acid profile, which means that every serving of Nitro-Tech® provides you with all the essential amino acids, including the 6.9 grams of BCAAs critical for building muscle. Plus you get the conditionally essential and dispensable amino acids, including 5.3 grams of glutamine and it's precursor.
Nitro-Tech® contains a research-proven 3-gram dose of creatine monohydrate, which combined with whey protein, helps to build more strength than regular whey protein. In a breakthrough study, subjects using the core ingredient combination in Nitro-Tech® increased their one-rep max bench press by 34 lbs., compared to only 14 lbs. for subjects using regular whey protein.
Take a look at other protein powders and you might be shocked by what you find! Some of these proteins are loaded with fat and some have over 10 grams of carbs per scoop! Nitro-Tech® doesn't fill your shaker cup with carbs – there are other supplements designed to do that. Instead, each scoop of Nitro-Tech® contains 30 grams of protein, primarily from whey protein isolate and whey peptides, with only 4 grams of carbs, depending on the flavor and no more than 2.5 grams of fat!
Enjoying a clean formula doesn't mean you have to deal with excess carbs and fat. For some companies, the taste of their protein is the only thing they have going for them, so they load up their protein formulas with cheap proteins that are easy to flavor, and then chase that with a load of flavoring in the form of sugar, carbs and fat. At MuscleTech we believe that you shouldn't have to sacrifice macronutrients for results. That's why our research team works closely with some of the top protein-flavoring professionals in the world, and each flavor of Nitro-Tech® is tested in internal taste tests.
The result is a great-tasting formula that doesn't pack the extra sugar and carbs you'll see in other protein powders. This gives you more protein per scoop and a better overall macronutrient profile.
Isolate Protein & Peptide Blend (Whey Protein Isolate, Whey Peptides, Whey Protein Isolate 97%), Whey Protein Concentrate , Natural and Artificial Flavors, Chocolate Cookie Crumbs (Rice Starch, Sugar, Cocoa (Processed With Alkali), Tapioca Starch, Palm Oil, Corn Starch, Natural Flavors, Salt, Sodium Bicarbonate, Soy Lecithin), Calcium Carbonate, Soy or Sunflower Lecithin, Gum Blend (Cellulose , Xanthan, Carrageenan), Enzyplex (Papain, Amylase), Salt, Sucralose, Acesulfame-Potassium, Creatine Monohydrate, Taurine, L-Leucine, L-Isoleucine, L-Valine, L-Glutamine.
|Amount Per Serving (44 g)
|100 g
|141 kcl / 598kL
|391 kcl / 660 kJ
|30 g
|86 g
|Total Carbohydrates
|3 g
|8 g
|· of which sugars
|1 g
|3 g
|Total Fat
|1 g
|3 g
|· Of which saturates
|1 g
|3 g
|· Of which cholesterol
|30 mg
|86 mg
|· Of which trans
|0 g
|0 g
|1 g
|3 g
|70 mg
|194 mg
|Super-Amino Matrix
|Creatine Monohydrate
|3000 mg
|8571 mg
|1000 mg
|2875 mg
|355 mg
|1014 mg
|25 mg
|71 mg
|71 mg
|71 mg
|100 mg
|286 mg
* Recomended Daily Allowance
† Recomended Daily Allowance not established
Comparative MuscleTech Nitrotech Performance Series - 907g
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MuscleTech Nitrotech Performance Series - 907g
Shipping MuscleTech Nitrotech Performance Series - 907g
- Delivery feeFree delivery on orders over €200
- Estimated deliveryDelivery 1 working day
- stock informationOnly 1 unit left!Stock information is continuously updated unless we have a problem with our system.
- Delivered at
The orders placed before 13:30 from Monday to Friday will be shipped on the same day. Orders placed by bank transfer will be carried out upon receipt of the full amount.
At fitnessdigital we seek complete satisfaction for our clients and we know that delivery charges are an inconvenience and therefore fitnessdigital offers free delivery for orders over €200. On orders up to €100 delivery costs are €9.99 and between €100 and €200 the delivery costs are €6.99. The shopping basket automatically updates the delivery costs. At fitnessdigital we also take great care over the delivery and always do everything possible to ensure that the delivery times are respected. For this reason we work with transport leaders such as TNT, DHL, DACHSER, DPD or UPS.
- Please note that if you order more than one product, you might receive them on different days and/or with different transport companies; in this case too we do our very best to respect delivery time of all the products ordered.
- The transport carriers will only deliver to the ground floor entrance of the building or property. Delivery does not include taking the merchandise up to a first floor nor does it include installment.
Not at home for the delivery? If an attempt at delivery is made and there is no one at home, the transport company will leave you a note instructing you to contact them so that you can confirm a new delivery date. When the transport company delivers the goods, before signing the delivery note, please check the following:
- That the number of packages coincides with the number indicated on the delivery note. If the number of packages does not coincide, please note this on the delivery note before signing for the delivery.
- That the packages do not show any signs of being deformed or damaged. If there is damage, please indicate "damaged package" on the delivery note.
If there is damage, it is very important that this is indicated on the delivery note as stated above and communicated to us within 24 hours from receiving the order, in order to process the necessary damage claim. We strongly advise you to send us photos of the damage to the package and/or products in order to give you a solution as quickly as possible.
Important: Damage claims on the content must be reported within 7 days of receipt. Otherwise, they cannot be accepted.
Payment methods MuscleTech Nitrotech Performance Series - 907g
Cash On DeliveryNo surcharge
You will receive the order at the registered address and the payment is made on delivery in cash. The cash on delivery option is only available for orders of 150 € or more.
Credit cardNo surcharge
Pay securely with the following credit cards: VISA, VISA Electron, 4B, or Mastercard
or with an authenticated credit card (Verified by Visa / Mastercard SecureCode).
If you have a credit card that allows you to purchase in internet, and you have a code or password that allows you to pay on-line, this is a good and comfortbale way to pay for you. Payment on-line means that your order will be paid for right after checkout, and is therefore very fast. fitnessdigital.cz is 100% secure. We guarantee the safety of your credit card information. All credit card information is handled with the utmost security and will never be released to any other organisation under any circumstance.
PayPalNo surcharge
Your order will be sent upon receipt of the PayPal confirmation of payment of the full amount. What is PayPal?
fitnessdigital could sometimes ask a customer to use a certain payment methods ( for instance if the information given to us is not complete or seems to include false information). This could be the case when we are not able to properly identify who the customer is. We could sometimes ask for specially added documents as well, in order to prove payment
Delivery costs, delivery time and terms and conditions for free delivery are the same for all payment methods
Cash On Delivery payments can be made in the local currency (€).
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text:
Huilin Wang Cornell is an associate in the firm's Project Finance and Development Group.
Before joining the firm, Ms. Cornell worked as an investment banking analyst and was a judicial extern for the Honorable Chief Judge Alex Kozinski of the U.S. Court of Appeals for the Ninth Circuit. She was previously a summer associate at Morrison & Foerster.
Ms. Cornell received her A.B. cum laude in economics from Harvard University and her J.D. cum laude from the University of Michigan Law School. While in law school, Ms. Cornell was an articles editor for the Michigan Journal of Private Equity and Venture Capital Law.
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