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HIV/AIDS News
NIAID-Supported Researchers Illuminate 3-D Structure of HIV Protein
Researchers supported by the National Institute of Allergy and Infectious Diseases (NIAID) have determined the three-dimensional structure of a key section of the protein that forms the core of the human immunodeficiency virus (HIV).
The protein, called the p24 capsid protein, assembles with identical proteins to form the cone-shaped structure that encloses the genetic material of HIV in a mature virus particle. In addition to its structural function, scientists speculate that the p24 capsid protein plays other important roles in the HIV life cycle.
Michael F. Summers, Ph.D., professor of biochemistry at the University of Maryland Baltimore County (UMBC), and his colleagues at UMBC and the University of Utah report their findings in the July 12 Science. Dr. Summers also will participate in a press conference on the UMBC campus on Thursday, July 11 at 2:00 p.m.
This important new information on the structure of the HIV p24 capsid protein suggests potential new targets for drug development, and provides new insights into the process of HIV replication," says Jack Killen, M.D., director of the NIAID Division of AIDS. "This work is especially impressive because Dr. Summers' students -- undergraduates as well as graduate students and post-doctoral fellows -- have played pivotal roles in his cutting-edge research."
Previously, Dr. Summers and his team solved the structure of two other HIV structural proteins: the p7 nucleocapsid, a protein found inside the viral core; and the p17 matrix protein, found between the core and the viral membrane.
The record of the UMBC group has been extraordinary," says Opendra Sharma, Ph.D., health scientist administrator in NIAID's Division of AIDS and the NIAID program officer for the UMBC grant. "Over the course of five years, they have provided three pieces of a remarkably difficult puzzle."
In their research, Dr. Summers and his colleagues used a technique called nuclear magnetic resonance (NMR) spectroscopy to determine in fine detail the structure of two-thirds of the p24 capsid protein. Using NMR, researchers can map the positions of hydrogen atoms in a molecule and the kinds of atoms that surround them.
Scientists have used NMR for the past decade to study proteins that do not form crystals, and therefore are not amenable to x-ray crystallography. NMR allows researchers to observe proteins in their natural state: in solution, where they are free to move.
However, the procedure is useful for only small molecules, and the p24 capsid protein is a large molecule that aggregates with other similar molecules. Therefore, the UMBC researchers initially were unsuccessful in their attempts to study the protein's structure with NMR.
"Picture the core of HIV as an eggshell composed of 2000 identical copies of the p24 capsid protein," says Dr. Summers. "Each piece of the eggshell is designed to aggregate with the others, and when we put these proteins in solution, they stuck together, becoming too large for us to study by our methods."
"Our big breakthrough came about a year ago when we figured out how to use enzymes to cut off the third of the molecule responsible for aggregation, which left us with a section of the molecule, called the amino-terminal core domain, that we could study."
Dr. Summers' collaborator at the University of Utah, Wesley I. Sundquist, Ph.D., had initially provided the UMBC group with large quantities of native p24 capsid protein, which he produced in E. coli bacteria using a special genetic engineering technique. For the current study, Dr. Sundquist and his group adapted their technique to produce large quantities of the amino-terminal core domain of the p24 capsid protein, without the part of the molecule responsible for aggregation.
The UMBC researchers found the structure of the p24 capsid protein to be unlike any other protein previously described. The amino-terminal domain has seven corkscrew-shaped "alpha-helices", two regions called "beta-hairpins," and a single, exposed loop.
The exposed loop may be of particular importance, says Dr. Summers, because it contains an amino acid -- Pro90 -- that binds a protein called cyclophilin A that HIV takes with it when it buds from a cell. The binding of cyclophilin A by Pro90 appears necessary for a viral particle to be infectious. If Pro90 is present in an abnormal form, HIV particles are not infectious, even though they appear normal. Researchers have previously hypothesized that the binding of cyclophilin A to the p24 capsid protein changes the conformation of the protein, thereby enabling the virus to release its genetic contents into a target cell.
In their experiments, Dr. Summers and his group observed that Pro90 exists in two separate conformations.
"One of these conformations may be necessary for the p24 capsid proteins to assemble to form the viral core, and the other conformation is necessary for the core to disassemble," he says. "Pro90 may serve as a molecular switch for capsid assembly or disassembly, with cyclophilin A either "flipping the switch" or locking it into a particular position."
"We now have a detailed picture of what the cyclophilin A binding site of the HIV p24 capsid protein looks like," Dr. Summers adds. "It may now be possible for experts in drug design to take this structure and develop a drug that would bind to the site and thereby block cyclophilin A binding, and perhaps HIV infectivity."
"The capsid proteins of other viruses have been successfully targeted in drug design," he notes.
Dr. Summers' collaborators include Rossitza K. Gitti, Ph.D., Brian M. Lee and Jill Walker, of UMBC; and Sanghee Yoo and Wesley I. Sundquist, Ph.D., of the University of Utah.
In addition to funding from NIAID, Dr. Summers and his team received support from the National Institute of General Medical Sciences (NIGMS) and the Howard Hughes Medical Institute, where Dr. Summers is an associate investigator.
NIAID and NIGMS are components of the National Institutes of Health (NIH). NIAID conducts and supports research to prevent, diagnose and treat illnesses such as AIDS and other sexually transmitted diseases, tuberculosis, asthma and allergies. NIH is an agency of the U.S. Public Health Service, U.S. Department of Health and Human Services.
NIAID press releases, fact sheets and other materials are available on the internet via the NIAID home page. The address is http://www.niaid.nih.gov.


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$19.00 NZD $30.00 NZD You Save 36% ($11.00 NZD)
Simply sophisticated – Look naturally chic with this glossy dark blonde. Be confident with healthier-looking hair that feels soft and smooth thanks to our ultra-conditioning, long-lasting colour.
Tints of Nature is a range of permanent hair colours, which condition while they colour. Free from many of the aggressive chemicals found in other hair colours, such as ammonia, resorcinol and parabens. Tints of Nature has been formulated with specially selected natural and certified organic ingredients and offers a gentler alternative, which will leave your hair looking gorgeous.
The colours are supported by a range of shampoos and conditioners, designed to maintain your locks in tip top form. These are packed full of natural and certified organic ingredients for a highly effective result every time.
Tints of Nature Permanent Hair Colours contain the lowest possible percentage of PPDs. Using certified organic extracts, it is one of the kindest ways to colour hair effectively, including grey.
1x Clarifying Shampoo 10ml
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1x Developing Cap
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1x Colour Gel 50ml
1x Colourfix 50ml
1x Shampoo 10ml
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"ICC" stands for "International Colour Code" and is a system of describing hair colour using a number and letter in an effort to ensure hair colours are consistent around the world. The numbers range from 1 (darkest) to 10 (lightest) followed by letters that describe the character of the colour. The colour images below are an indication of colour only and may appear differently on other computer monitors, and on your hair. For maximum grey coverage use the "Natural" colours 1N – 8N.
Because of the more natural method used by Tints of Nature, the colour of the hair can only be lifted by one shade (meaning you can only lighten your hair by one level). You may wish to use our Lightening and Highlighting Kits.
The Tints of Nature colours can be mixed together to create your own shades. Always consider your skin tone, the colour of your eyes, as well as the predominant colours in your wardrobe before choosing your new hair colour. Here are a few handy hints to get you started:1. If you are mixing two colours with different base numbers together, you will usually end up with a base shade somewhere in the middle, for example, if you mix together 3N and 5N, you will achieve a 4N.
2. The ash shades (4C, 6C and 8C) are ideal for counteracting red tones in red.
3. Remember to measure colours accurately for the best result.
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-Is a cleaner, less harmful alternative when compared to the more highly chemical bases used by many other hair colour products
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-Covers all grey hair - gently
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-Advanced, professionally tested formula for accurate results
-Likely colour result indicator incorporated on sleeve.
This product contains ingredients which may cause skin irritation to certain individuals. It contains phenylene diamines. A preliminary test according to the accompanying directions should be made before use. This product must not be used for dyeing eyelashes or eyebrows; to do so may be injurious to the eye. KEEP OUT OF REACH OF CHILDREN.


text: Snacks Snacks Snacks:Tuna in the "fresh pouch". Doesn't require draining Beef Sticks such as Slim Jims Crackers and a Cheese spread. CAUTION: Spray-cans may explode! Potted meat and crackers Single servings of bagged chips. Cookies. Tuna with crackers. Triscuits and Ritz crackers Lunchables. Many varieties that don't have to be refridgerated. Candy, of course. Snack Cakes M & M's Graham crackers. Chocolate-dipped pretzels Pre-packaed brownies. Licorice Bubble gum Snack mixes like Chex Mix Nuts - Cashews, peanuts, etc. Pretzels Rice Krispie Treats! Applesauce, pudding or fruit cups with the pop-off lids. Trail mix Prev Next


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Frequent Links
Basketball court
Basketball courts come in different shapes, sizes, and colors. In the NBA, the court is 94 feet by 50 feet (28.65m by 15.24m). Under International Basketball Federation (FIBA) rules,[1] the court is minutely smaller, measuring exactly 28 m by 15 m (91'10.4" by 49'2.6"). A high school court is slightly smaller, at 84' by 50' and some elementary schools have courts measuring 74' x 42'. In amateur basketball, court sizes vary widely. The baskets are always 10' (3.05m) above the floor (except possibly in youth competition). Basketball courts have a three-point arc at both baskets. A basket made from behind this arc is worth three points; a basket made from within this line, or with a player's foot touching the line is worth two points. The free-throw line, where one stands while taking a foul shot, is located within the three-point arc.[2]
The height of the underside of the roof structure, or the ceiling if there is one, above the floor is specified by each sport's governing body, and this is a critical design factor. Badminton, tennis and trampolining require an unrestricted height of 9.1m for international competition, while 7.6m is necessary at C level in all sports except those for which height is not critical. In general a basketball court should have a minimum clearance of 25 feet (7.7m), although a ceiling height of at least 27 feet (8.23m) is recommended.
Diagram of basketball court and backboard
- Basketball court fiba.svg
A diagram of an FIBA basketball court
- Basketball backboard and basket.svg
The backboard and basket
- 2008 NCAA Basketball backboard dimensions.svg
NCAA backboard and basket (2008)
Layout prescribed by the rules of the International Basketball Federation (FIBA), the National Basketball Association (NBA), and a National Collegiate Athletic Association (NCAA).
Dimensions table
|U.S. Junior H.S.
|Court length
|94 ft
|28.65 m
|91.86 ft
|28 m
|Same as NBA
|84 ft
|25.60 m
|74 ft
|22.56 m
|Court width
|50 ft
|15.24 m
|49.21 ft
|15 m
|Same as NBA
|42 ft
|12.80 m
|Rim height
|10 ft
|Same as NBA
|Restricted arc radius
|4 ft
|1.22 m
|4.10 ft
|1.25 m
|Same as NBA
|3 ft
|0.91 m
|Center circle diameter
|12 ft
|3.66 m
|11.81 ft
|3.6 m
|Same as NBA
|3-point line distance from the basket
| 23.75 ft
22 ft in corner*
| 7.24 m
6.70 m in corner*
| 22.15 ft
21.65 ft in corner†
| 6.75 m
6.60 m in corner†
|Same as FIBA
|20.75 ft
|6.32 m
|19.75 ft
|6.01 m
|Same as high school
|Key (shaded lane or
restricted area) width
|16 ft
|4.88 m
|16.08 ft
|4.9 m
|Same as NBA
|12 ft
|3.66 m
|Same as NCAA
|Free-throw line distance from point on the floor directly below the backboard
|15 ft
|4.57 m
|15.09 ft
|4.6 m
|Same as NBA
† The FIBA three-point line is 2.95 ft (0.90 m) from the sideline in a zone starting at the baseline and ending when it crosses the 22.1 ft (6.75 m) arc. The 21.65 ft (6.60 m) measurement applies only at a point where a line parallel to the baseline intersects the long axis of the court and the center of the basket.
Sections of the basketball court
Center circle
The only two players permitted to enter this area prior to the tipoff are the players contesting the jump ball (usually but not always centers). Both players jump when the referee throws the ball in the air, each attempting to tap the ball into the hands of a player of their own team.
Three-point line
The three-point line is the line that separates the two-point area from the three-point area; any shot converted beyond this line counts as three points. If the shooting player steps on the line, it is counted as two points only. Any foul made in the act of shooting beyond the three-point line would give the player three free throws if the shot doesn't go in, and one if it does.
The distance to the three-point line from the center of the basket varies depending on the level or league, and has changed several times. These are the current distances, with the league or level using each distance:
19.75 ft (6.01 m): High School
20.75 ft (6.32 m): NCAA
21.65 ft (6.60 m) to 22.15 ft (6.75 m): WNBA and FIBA
22 ft (6.71 m) to 23.75 ft (7.24 m): NBA
The NBA adopted the three-point line at the start of the 1979–80 season. This is of variable distance, ranging from Script error: No such module "convert". in the corners to Script error: No such module "convert". behind the top of the key. During the 1994–95, 1995–96 and 1996–97 seasons, the NBA attempted to address decreased scoring by shortening the overall distance of the line to a uniform Script error: No such module "convert". around the basket. It was moved back to its original distance after the 1996–97 season. FIBA and the NCAA both adopted the three-point line in 1985.
In college basketball as well as in most high school associations in the United States, the distance is 19.75 feet. On May 26, 2007, the NCAA playing rules committee agreed to move the three-point line back one foot to 20.75 feet for the men. This rule went into effect for the 2008–2009 season. The three-point line for women (NCAA) moved back one foot to 20.75 feet at the start of the 2011–2012 season.
The international distance, used in most countries outside the United States and in FIBA and WNBA competition, is currently 6.6 m (21.65 ft) to 6.75 m (22.15 ft).
The perimeter is defined as the areas outside the free throw lane and inside the three-point line. Shots converted (successfully made) from this area are called "perimeter shots" or "medium-range shots." If a player's foot is on the three-point line, the shot is considered a perimeter shot.
Low post area
The low post is defined as the areas that are closest to the basket but outside of the free throw lane.[4] This area is fundamental to strategy in basketball. Skilled low post players can score many points per game without ever taking a jump shot.
The key, free throw lane or shaded lane refers to the usually painted area beneath the basket; for the NBA it is Script error: No such module "convert". wide, for the NCAA it is Script error: No such module "convert". wide; for both instances it extends Script error: No such module "convert". from the backboard. At the top of the rectangle is the free-throw line, behind which players shoot uncontested shots when they're fouled. A circle is drawn around the free-throw line with a Script error: No such module "convert". radius; this is used for jump ball instances, as is done at the center circle. Two 6-inch hash lines, 3 ft from the free throw lane line and 5 ft 8 in from the free throw line, show the lower defensive box linked to the restricted area.
For FIBA tournaments, since October 2010 the key has been a rectangle 4.9 m wide and 5.8 m long. Previously it was a trapezoid 3.7 meters (12 ft) wide at the free-throw line and 6 meters (19 feet and 6.25 inches) at the end line.
The key is primarily used to prevent players from staying beneath the basket of the opponents' team for long periods (maximum three seconds).
Restricted area arc
The restricted area arc is a semi-circular arc drawn around the area directly underneath the basket. With some exceptions, members of the defending team cannot draw charging fouls in this area. The restricted arc in NBA and WNBA competition has a radius 4 feet (1.22 m) from below the center of the basket. The restricted arc in NCAA competition (both men's and women's) is of radius 3 feet (0.91 m) from below the center of the basket.
Other lines
On NBA floors, two hash marks are drawn at the end lines near the key to mark the area known as the lower defensive box. A defensive player is allowed to draw a charging foul within the restricted arc if the offensive player receives the ball and/or starts his drive within this area.[5]
Also, two lines are drawn on each of the sidelines, 28 feet from each of the endlines, which designates the extent of the coaching box and bench. This line marks the farthest extent a coach (aside from the sidelines) can stand. Directly behind this area is the team bench.
On the half-court line of NBA floors two lines extend outside the playing court, designating the place where substitutes wait before they can enter the playing court; directly behind this area are the various off-court officials such as the timekeeper and reserve referee.
FIBA changes
On April 26, 2008, FIBA announced several major rules changes involving the court markings. These changes took effect for major international competitions on October 1, 2010, after that year's World Championships for men and women, and became mandatory for other competitions on October 1, 2012 (although national federations could adopt the new markings before 2012). The changes were as follows.[6]
- The shape of the key changed from a trapezoid to a rectangle as it is in the NBA, with NBA dimensions.
- The three-point line moved back to 6.75 metres (22 ft 1.7 in) from 6.25 metres (20 ft 6.1 in), compared to Script error: No such module "convert". for the NBA at the top of the arc.
- The FIBA adopted the NBA's restricted area arc with a marginally wider radius of 1.25 metres (4 ft 1.2 in).
See also
- ^ "Official Basketball Rules 2006" (PDF). International Basketball Federation. 2006. Archived from the original on 6 April 2007. Retrieved 2007-04-14.
- ^ Wissel, Hal (1994). Basketball: steps to success. United States: Human Kinetics Publishers, Inc. pp. ix. ISBN 0-7360-5500-2.
- ^ "NCAA Court and Equipment Rules" (PDF). 2012. Retrieved 2012-06-17.
- ^ Basketball Glossary Terms, Definition, Lane violation, Low post
- ^ http://www.nba.com/nba101/misunderstood_0708.html
- ^ "The FIBA Central Board approves historic rule changes" (Press release). FIBA. 2008-04-26. Archived from the original on 30 April 2008. Retrieved 2008-04-28.
External links
|Wikimedia Commons has media related to Basketball courts.
- Information on Building, Choosing, Maintaining a Basketball Court
- Free Basketball Court Layout Template
- FIBA Central Board (2010-04-17). "Official Basketball Rules 2010: Basketball Equipment" (PDF). International Basketball Federation. Retrieved 2010-07-15.


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Mortgage lending will not return until firms figure out how to better automate an underwriting process overloaded with new rules but still being done by hand, according to entrepreneur Bill Dallas.
Dallas founded First Franklin, a large mortgage operation, and his newest venture is Skyline Mortgage located on the West Coast. Dallas is building out a system that will allow his network of brokers to underwrite mortgages by checking off various compliance issues from new Dodd-Frank provisions to Real Estate Settlement Procedures Act requirements.
"Mortgage lending is not hard any more. There's one product. Here's your 30-year fixed. Here's your rate. When do you want to lock?" Dallas said at the HousingWire REthink Symposium Thursday.
The difference now is the compliance. Regulators are no longer satisfied with examining a completed loan, Dallas said. They want to look at every step of the process. Large banks, such as Bank of America (BAC) and Ally Financial are on their way out. And smaller lenders, usually those most adverse to investing in the technology needed to comply, will have to take their place.
"Whoever has a 70% market share dies," Dallas said. Nervous laughter ensued in the audience.
There will be plenty of opportunity for growth, he expects. In 2012, he expects $531 billion in purchase mortgages with $400 billion more in refinances. Next year, as interest rates are expected to increase, purchase mortgages could rise to $859 billion with roughly $287 billion in refis, according to his models.
Compliance is key. For him, the housing bottom is right now, and he said he is getting back into the space. Convincing borrowers that a mortgage isn't a terrible thing will be the main turning point.
"We're like the airlines," he said about the mortgage baking industry. "We just don't want to die, and we're happy if our luggage comes out at the end."


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What to does chiropractic treatment entail?
Chiropractic therapy is a form of therapy that is used to diagnose and treat health problems that affects the nerves, muscles, bones, and joints of the body. A chiropractor is the person who provides chiropractic therapy. When you visit a chiropractor for the first time to receive therapy some of the questions they will ask you about are; the past injuries or illnesses, your current health problems and the medicines that you are taking, your lifestyle, the diet, sleep habits etc. It is very important to inform your chiropractor about any physical problems you may be experiencing. If you have a feeling of weakness or any other nerve related problems feel free to say it. This kind of treatment offers a sure remedy to back pain that has lasted for three months or less. You could also find relief with this kind of therapy if you are experiencing neck pain. You should however avoid this kind of therapy if you have bone fractures or tumors.
After you have been cross examined by the health expert they will then proceed to conduct a physical examination on you. Things like checking how your spine is moving called spinal mobility test will be carried out on you. The expert will also carry out some specialized test on you; checking your blood pressure and x-rays. These tests are often conducted on you in order to find out what could be causing your backache. Sometimes after these tests have been conducted on you, treatment can be administered to you immediately or on your second visit.
During treatment the health expert may ask you to lie down on a special type of table where he/she will do to you what is called the spinal manipulations. This is often done by hand where a joint is moved in your spine to the end of its range accompanied by a soft shove. This will help in the realignment of the bones of your spine in order for them to be straighter. The other treatments that the expert may conduct on you are massage on your soft tissues. Some people often experience little pain and fatigue for some few days after receiving this kind of treatment. This is always due to their body's reaction in adjusting to the new alignment. It is however not good that you feel pain from the manipulation.
For people with back or spinal problems opting for chiropractic care should go for more than one session for them to be able to alleviate their problem. In some instances this therapy lasts several weeks. During your first stages of therapy your chiropractor may suggest for you more than two weekly short sessions at first lasting between 10 and 20 minutes each. If you are responding well to treatment then you may only be required only once weekly. If you see that you are feeling much better then you can talk with your physician about how you are feeling based on the goals you set out in your first session.


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Thursday, November 30, 2006
Thursday Thoughts
May I just comment on the cost of a nice suit, shirt, silk tie, belt, and lace up dress shoes for a 17 year old young man? Holy cow. I hope he enjoys the Winter Dance, that's all I can say. Plus the tickets and wrist corsage for his date. And dinner before the dance at a nice Italian restaurant. You'd think it was prom.
I used the heater in my new car today for the first time. Works great. Did I mention I have a new vehicle? For the first time in over 20 years I have a new, used car. Yeah, that's right. It is a 2006 so with the 2007 models out now, my car becomes used. It had 96 miles on it at delivery. But most importantly, it has the new car smell. What a luxury for this girl. When I married the husband, we became perennial used car buyers. We have had some great ones, at great deals. My first real adult working experience was at a automobile dealership so I am well aware of the instant depreciation of autos once they leave the dealership's lot.
This car is a Chevy Impala with the bigger engine in it. Maroon with biege cloth seats. I christened the cd player yesterday with my Il Divo Christmas album. I love my Il Divo boys. They're so pretty and have glorious voices.
The car I drove the longest period of time was a Mercedes 300D. It was a great car. Lasted forever. I've had good luck with Mazda's, too. I have had two different models of them. Both of those I bought new as a single woman. I worked for the dealership.
Anyway, I guess the old adage of everything comes in three's is true in Hollywood, huh. First Mel Gibson, then Michael Richards and now Danny DeVito having a meltdown. DeVito was on the View yesterday and according to the clips I saw, was drunk and obnoxious. He fell into the standard cheap laughs with the Bush is stupid crowd. Too bad. I liked him. No more. He was on Fox and Friends earlier and I saw him on that before starting the day and he appeared sober and was fine. Of course I wasn't terribly alert myself at that hour. Doesn't say much for his comedic skills when he does the same pap that Letterman and Jon Stewart do. Not to mention it is just not true. Bush isn't a great speaker but his intelligence is greater than his critics. I guess they still prefer a haughty French looking Boston accent to a Texas twang. It's one of the last accepted prejudices, isn't it, that a slower accent means you lack intelligence.
Bless his heart.
6 comments:
- aka_Meritt said...
I know! Isn't it awful how a simple dance (Winter Dance, Homecoming, Spring dance) has turned into another PROM? OMG.
Memories of two prom nights and two winter formals still haunt my pocketbook and by comparison we got by cheaply.
There was an article in the local paper a couple months ago about a sweet 16 party thrown by a teen's mom in which the birthday girl was carried in on a litter by 6 brawny boys, had a supposedly famous DJ there in person and was presented with a new BMW. Sheesh, some people, some people's kids and the news media.
Today's paper had some incredible photos from Houston of people in the wind! Hope you are grounded.
That should read - by comparison with some of J's schoolmates - we got by cheaply. I am tossing the many college ring/diploma fancy framing ads she receives immediately.
An irony and I'm sure an unintended coincidence was that the same day we received her college tuition/dorm/fees bill the college sent me a solicitation for Alumni Giving. Ha!
- srp said...
We lucked out on the formal wear thing. For her birthday we went to Birmingham Galleria Mall and Dillards was having one of their MEGA sales. Apparently, in Alabama, prom is in the beginning of April. All the dresses were 75 - 80% off. We made like bandits.... she found four formal dresses and we got them for around $100 .... TOTAL!! I love Dillards in April and September.
I didn't see the View as I think it has withered. They made a big mistake with Rosie O'Donnell on there. She is the most obnoxious person I've ever seen; obnoxious, loud, uncouth, disrespectful, hateful, and every other nasty adjective I can think of. I wouldn't waste my viewing time on her. Whoever thought she would make a good mother and let her adopt must also be insane, or star struck. Those kids don't stand a chance.
- Beverly said...
I saw DeVito on Fox as well, and he seemed o.k. to me, and then I saw the news of The View (which I have never watched.) He didn't seem like the same person. Too bad.
Congratulations on the new car. I got a new car in 2005. I had driven a Toyota Avalon for 9 years...wonderful car, but I wanted something newer, and since I have problems with my eyes, I knew that I should get one now, while I can still see well enough to drive. So I took the plunge. Yes, the new car smell is wonderful.
They're wonderful until someone puts a ding in it...then it feels just a bit damaged. Enjoy. you deserve it.
- colleenR said...
Nobody minded Clinton's twang. Many questioned his intergrity but I don't think anyone thought he was stupid.


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Ultra-creamy Fontina cheese and a layer of black-olive tapenade give this an unctuous, satisfying quality that is usually missing from other veggie pizzas. What to drink: Dry rosé or a spicy Rhône-style red.
- Yield
- Makes 3 medium pizzas
- Dough
- 1 1/4 cups warm water (105°F to 115°F)
- 1 envelope (1/4 ounce) active dry yeast
- Generous pinch of sugar
- 3 1/4 to 3 3/4 cups all purpose flour, divided
- 1 tablespoon extra-virgin olive oil
- 2 1/2 teaspoons coarse kosher salt
- Topping
- 3 medium zucchini (about 1 pound total), trimmed, cut lengthwise into 1/4-inch-thick slices
- 2 small eggplants (about 1 1/2 pounds total), cut lengthwise into 1/4-inch-thick slices
- 3/4 cup (about) extra-virgin olive oil, divided
- 3/4 cup purchased black-olive tapenade* (about 5 1/2 ounces)
- 3 tablespoons minced fresh marjoram or fresh oregano
- 3/4 teaspoon dried crushed red pepper
- 1 1/2 cups (packed) coarsely grated Fontina cheese
- 1 cup freshly grated Pecorino Romano cheese
- 1/2 cup chopped fresh Italian parsley
- For dough:
- Stir 1 1/4 cups warm water, yeast, and sugar in large bowl to blend. Let stand until yeast dissolves, about 10 minutes. Whisk in 1 cup flour; let stand in warm draft-free area until bubbling, about 30 minutes.
- Stir oil and salt, then 2 cups flour into yeast mixture. Knead dough in bowl until almost smooth and beginning to pull away from sides, adding 1/4 cup more flour to prevent sticking. Turn dough out onto floured surface; knead until smooth and elastic, adding more flour by tablespoonfuls as needed (dough should be slightly sticky), about 7 minutes. Place dough in lightly oiled large bowl; cover with plastic wrap. Let dough rise in warm draft-free area until doubled in volume, about 1 1/2 hours.
- Meanwhile, for topping:
- Prepare barbecue (medium heat). Arrange zucchini and eggplant slices on 2 large baking sheets. Brush vegetables with oil; sprinkle with salt and pepper. Grill until tender and golden brown, about 4 minutes per side. Transfer to platter.
- If using charcoal barbecue, remove grate and arrange coals so that 1 side of grill is hot and 1 side is cooler (for gas barbecue, adjust burners accordingly).
- Sprinkle 3 baking sheets with flour. Punch down dough. Divide dough into 3 equal pieces; roll out each piece on floured surface to 12x8-inch oval. Transfer to prepared baking sheets. Brush dough tops with oil. Place ovals, oiled side down, on hot side of grill rack and grill until bottoms are firm (watch closely to avoid burning), about 3 minutes. Turn crusts over; grill until dough is set, about 2 minutes. Transfer to baking sheets, grill mark side up.
- Spread 1/4 cup tapenade over each pizza; arrange grilled zucchini and eggplant slices over. Sprinkle each with 1 tablespoon marjoram and 1/4 teaspoon crushed red pepper. Drizzle lightly with oil. Sprinkle each with 1/2 cup Fontina and 1/3 cup Pecorino Romano. Return pizzas to cooler side of grill. Cover and grill until cheese melts, about 5 minutes. Sprinkle pizzas with parsley; slice and serve.
- *A thick paste or spread made from brine-cured olives, capers, anchovies, and seasonings; available at some supermarkets, specialty foods stores, and Italian markets.
Related Video
Nutritional Info
- Calories1670
- Carbohydrates141 g(47%)
- Fat102 g(157%)
- Protein53 g(106%)
- Saturated Fat30 g(149%)
- Sodium2208 mg(92%)
- Polyunsaturated Fat9 g
- Fiber18 g(70%)
- Monounsaturated Fat58 g
- Cholesterol122 mg(41%)


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The gathering of friends... and of enemies. Where, what and when will the next meeting be and what experience will it hold?
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The Free Software Foundation Europe is a non-profit non-governmental organisation. Our work is made possible by a community of volunteers, supporters and donors. Your donations are critical to our strength and autonomy. They enable us to continue working for Free Software wherever necessary, and to be an independent voice.
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In some countries, donations to us can be deducted from income tax. Currently, this is the case in Germany, the Netherlands, Luxembourg, and Switzerland. A donation receipt is generally sent in the beginning of the year for donations received the previous year.


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Coloradan Guy Short serves as Michele Bachmann's national director
Guy Short apparently has a thing for tough, driven, controversial and conservative women.
The Erie resident served as U.S. Rep. Marilyn Musgrave's chief of staff until she lost her re-election bid in 2008. Now Short is serving as national director for Michele Bachmann's presidential bid.
Short served as the Minnesota Republican's general consultant on her last congressional campaign, helping her raise a record $13 million, and has been on her presidential campaign from the start, first as a senior adviser.
"I also started and direct her leaderhip pac — Michele's PAC Michelepac (Many Individual Conservatives Helping Elect Leaders Everywhere)," he said. "I still live in Colorado but I've been traveling nationally for Michele Bachmann and, as you can imagine, spending most of my time in Iowa, New Hampshire and South Carolina."


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|Assistant Coach (Vol)
|(617) 495-4853
|Previous College:
|Connecticut College 2006
|Second Season
Former Boston Celtics video coordinator Brian Adams was named an assistant coach with the Harvard men's basketball team on June 15, 2011.
In his first year in Cambridge, Adams and the Crimson established a school record with 26 victories, and Harvard won its second straight Ivy League title, earning a berth in the NCAA tournament for the first time since 1946. The Crimson swept the Battle 4 Atlantis tournament and reached as high as No. 21 in the ESPN/USA Today poll and No. 22 in the AP poll.
During the 2012-13 season, Harvard went 20-10 overall and posted an 11-3 mark in conference play en route to the Crimson's third consecutive Ivy League crown. While making its second straight NCAA tournament appearance, the Crimson upset third-seeded New Mexico in the second round, earning the program's first postseason victory. Siyani Chambers was tabbed the Ivy League Rookie of the Year, and he, along with Wesley Saunders, received All-Ivy first team honors.
Adams, who spent the five years with the Celtics, was a member of the organization when Boston won the NBA title in 2008. After serving as a video intern for the Celtics in 2005-06, Adams was promoted to video coordinator and spent four seasons in that capacity with the franchise.
With the Celtics, Adams was responsible for recording and editing all of the Celtics' and upcoming opponents' games, as well as providing scouting video used in pre and postgame viewings with the Celtics and the team's coaching staff.
A native of Pine Plains, N.Y., Adams began his career as a basketball operations intern for the New York Knicks. He ran track & field and was the men's basketball team manager as an undergraduate at Connecticut College, where he earned a bachelor's degree in psychology in 2006.


text: Welcome to "Chat-up lines"! A South Park Doujinshi from CraigTucker and me. Pairing: Craig x Stan Story: Stan hates Craig and his friends are fags! They haven't time for him.. Bad friends.. But in a chatroom.. he meet a guy.. and he is cool. ..and they will be friends... !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! PART 2 !!!! http://www.smackjeeves.com/comicprofile.php?id=121933 !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! WE LOVE YOU!


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FREE DOWNLOAD: "FILTER Magazine Presents: Milo Turns 50" Full Descendents Covers Album
By Staff on January 17, 2013
Getting old sucks. We all know it, we all feel it and it helps if you have some great friends to get you through. To help Descendents frontman Milo Aukerman celebrate the big 5-0 this January, we asked some radical musicians to pay tribute to the Manhattan Beach punk band for an exclusive covers album.
We are proud to announce the release of FILTER Magazine Presents: Milo Turns 50.
The 13-song compilation features reinventions of quintessential Descendents tracks by artists like FIDLAR, Mike Watt, YACHT, Tijuana Panthers, Milo Greene and The Bronx.
Download the entire album HERE and check out all of the details below. We'd like to give a huge thanks to Bill Stevenson and the Descendents, all the artists, Jason Powell, Chris Shary and Vanessa Burt.
Happy Birthday Milo!
FILTER Magazine Presents: Milo Turns 50 track listing
1. FIDLAR (featuring Brian Rodriguez)
"Suburban Home"
2. Mike Watt + The Secondmissingmen
"Kabuki Girl"
3. The Henry Clay People
"Clean Sheets"
4. The Bronx
5. Edsel
"Good Good Things"
6. Good Riddance
"Sour Grapes"
7. Tijuana Panthers
"Can't Go Back"
8. Milo Greene
"Ride the Wild"
10. Bobby Birdman
"I Don't Want To Grow Up"
11. Thrillionaire
12. Ben Bridwell of Band of Horses
Curated by FILTER Magazine, 2013.
Songs recorded November 2012-January 2013.
Mastered by Jason Powell.
Art by Chris Shary.


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Office of the Attorney GeneralJohn J. Farmer, Jr., Attorney GeneralJerry Fischer, Director
Kickoff of Summer '01 Initiatives to Combat Underage Drinking
Division of Alcoholic Beverage Control (ABC) Director Jerry Fischer;Division of Highway Traffic Safety Director Colonel Peter J. O'Hagan;Ocean County Prosecutor E. David Millard;New Jersey State Police Major Frank Simonetta;Partnership for a Drug-Free New Jersey Chairman Joseph P. Miele;Century Council Director of Programs Gary Decker;Law enforcement officials from the State Police ABC Enforcement Unit, Pt. Pleasant Beach Police Department and shore towns participating in the Cops in Shops program;Representatives from the licensed beverage industry, as well as local, county, and state government officials.
Additionally, the Division of Alcoholic Beverage Control, in cooperation with the Partnership for a Drug-Free New Jersey, will play a 30-second television public service announcement (PSA) and a 60-second radio PSA designed to inform young people both about the potential dangers of underage drinking, as well as the serious penalties youth can face if they drink. Copies of the TV PSA will be available.
Continuing efforts to deter drunk driving and drug use in shore towns will also be discussed.
Tuesday, June 19, beginning at 1:30 p.m.
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Last Updated:
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Guru (Gangstarr) & Solo Says Southern Rap Is Not Hip Hop!
Istatus reports "New Album GURU 8.0 in stores 5.19.09: Guru & Solar consider Southern Rap "NOT" Hip Hop (2min mark), talks about Rap Beefs, offers counseling to Chris Brown and Rihanna (6:50 mark), and taking a jab at Ice-T for beefing with Soulja Boy (5:35 mark)?? "
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Top Downloads
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English Thai Online Dictionary
Homepage Download Link broken?
License: Freeware
Version: 1.0
Company: Bede Products
Language: English
Size: 163 K
Category: Dictionaries
OS support: Symbian, PocketPC, Android, BlackBerry
The English Thai Online Translator is a tiny and absolutely FREE language software solution. It can be used to translate from English to Thai and from Thai to English using the internet connection on your device. Running on cell phones (mobile phone) and mobile devices compatible with the J2ME specifications CLDP 1.0 and MIDP 2.0 or later including Blackberry, Palm, Windows Mobile (PocketPCand Smartphone), Android and games consoles (PSP Nintendo DS) installed with a compatiable JVM and linked to the internet via a wireless connection. Instructions and offline English Thai dictionaries are available from http://www.mobiledictionary.co.uk.
File Distribution Notice of English Thai Online Dictionary Freeware -
English Thai Online Dictionary Free Download - 2000 Shareware periodically updates software information of English Thai Online Dictionary from the publisher, so some information may be slightly out-of-date. You should confirm all information before relying on it. Software piracy is theft, Using English Thai Online Dictionary crack, password, registration codes, key generators, serial numbers is illegal.
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by infinite_resolution
Multiple Artboards Roundup–Tutorials, Resources and More
Contributed by Terry Hemphill, Illustrator Product Marketing Manager
Since there's been a lot of discussion here on multiple artboards in Illustrator CS4, I want to round out that focus with links to resources for customers who are just becoming familiar with this new feature or customers who have downloaded the free 30-day trial and are looking to experiment.
First, if you're using an older version of Illustrator and would like to experience multiple artboards in Illustrator CS4, you can download the Illustrator CS4 free trial here.
AdobeTV has a number of free video tutorials on multiple artboards in Illustrator CS4:
Some other great tutorials:
I'm sure I've missed many other great resources, so if you've one you'd like to share with others, please let me know.


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The weight is finally right for the "Price is Right" host.
"I was sick of being fat on camera. Really I just got sick of it," newly slimmed down game-show host Drew Carey told People magazine at the "CBS, Showtime and The CW TCA Party" in Beverly Hills on Wednesday.
The diabetic former star of "The Drew Carey Show" detailed the skinny on his weight loss regime, which he credited with helping him lose 80 pounds since January.
"I have cheated a couple of times, but basically no carbs, not even a cracker," Carey, 52, told People.
Carey said that his old diet -- which consisted of pizza, corn, beans and starches -- has been replaced by heathier choices including grilled chicken and steamed vegetables. As far as drinks go, no more coffee, tea or soda. Water is his sole beverage of choice, he said.
Besides the healthier eating habits, Carey dished that he has employed "lots of cardio" on daily workouts.
"About 45 minutes of cardio, at least 45 minutes of cardio," Carey said of the routine.
Carey's pant size has shrunk from a size 44 in January to a 33-34 now, he said. He is aiming to lose an additional 10lbs and become a size 32.
"Once I started losing weight, again, like once I started dropping a couple of pant sizes, then it was easy 'cause once you see the results, then you don't wanna stop," he said.


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George Lopez is known for being a funnyman, but he got very serious about the issue of bullying on Tuesday's Access Hollywood Live.
"We all were bullied. Here's what we have to understand: We cannot live in the past. We were all bullied as kids. I had the biggest hair and the darkest skin," George told Access Hollywood Live's Billy Bush and Kit Hoover. "What we have to do now is save the kids who are being bullied on computers and bullied in school and bullied by friends and bullied on Facebook."
VIEW THE PHOTOS: Conan O'Brien Returns To Late Night With 'Conan'
The "Lopez Tonight" host, who has a young daughter – Mayan — said he protects her by keeping her away from a host of websites.
"I am a parent. I do not allow my daughter to have a Facebook page or a MySpace page or Twitter," George continued. "If you're looking for positive, don't look to Twitter, and for us who are older, let's not go into the past and talk about our bullying, but help kids now."
VIEW THE PHOTOS: Hottest Hollywood Dads!
When Billy asked what people can do help stop bullying, George said parents need to get involved with their kids.
"We focus our attention on computers and parents being parents in their own home, not allowing their child to dress provocatively, to not allow Facebook and MySpace and to have text messages," he said. "You have to eliminate the electronics because it's almost like a weapon that kids aren't supposed to have."
In related George news, the funnyman celebrated his Season 2 premiere last night on TBS, and he told Billy and Kit he had no problem following Conan O'Brien for the first time.
VIEW THE PHOTOS: Photo Fun With Hollywood's Hottest Comedians!
"I'm happy that Conan is on the air and we're both partners and looking to the future," George said.
George, whose show was moved to midnight to accommodate "Conan," said he and the redheaded star are reaching a whole new audience.
VIEW THE PHOTOS: The Latest Star Sightings
"He and I to go into the future of late night TV – if you look at David Letterman and if you look at Jay Leno — they're in their 60s and the audience reflects that," George said. "We're not. We're still in our 40s and it's a much younger, much more diverse show and it's important. I'm not sure if anybody's aware, but diversity is on the rise."
"Lopez Tonight" airs at midnight on Mondays-Thursdays on TBS.
Copyright 2010 by NBC Universal, Inc. All rights reserved.
This material may not be published, broadcast, rewritten or redistributed.
Related Content from AccessHollywood.com:
PLAY IT NOW: George Lopez On Arizona's 'Unconstitutional' New Immigration Law & Sandra Bullock's Adopted Baby
PLAY IT NOW: T.G.I.F. - Does David Beckham Want To Become A U.S. Citizen? (November 5, 2010)
More from Access: [ George LopezLatinoTV One ]


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"Operation ID: Woodhaven" will take place this Saturday, April 27, from 10 a.m. until 2 p.m. at the office of the Woodhaven Residents' Block Association, 84-20 Jamaica Avenue.
The program involves engraving a serial number on your portable valuables such as bicycles, cell phones, laptops, iPads, and iPhones, and registering the information with the NYPD. And as a bonus, you will be able to sign up your automobile in your choice of free anti-theft programs.
There are a few really good, simple reasons you should take a few moments this Saturday to take part in Operation ID: Woodhaven, including the fact that marked property is more difficult for a thief to sell, and recovered property can easily be identified and returned to the rightful owner.
In recent years, portable valuables such as cell phones and laptops have become popular targets of thieves. At the WRBA we've heard tales of the NYPD busting thieves only to find a cache of stolen items that, because they are unidentifiable, will probably sit in a storage room.
We have also heard many stories from parents whose children have had these items stolen and, unfortunately, we rarely (if ever) hear tales of those items being returned.
Operation ID: Woodhaven adjusts the odds in your favor and increases the chances that your stolen goods may be returned to you. And with warmer weather coming and more people out and about on their bicycles, thieves will be salivating at the chance to ride away with a free bike.
If you are out riding your bike this Saturday, stop by and get your bicycle registered. It takes just a few minutes.
Here is one thing that I can guarantee you. If you read this article and do not take advantage of this free program, if you are victimized by a thief you will be kicking yourself and asking why you didn't take just a few moments to take part in Operation ID: Woodhaven.
As a bonus, you will also be able to register your autos in the HEAT and CAT programs. When you register for these programs you will get a decal which will be affixed to your vehicle's rear window.
Combat Auto Theft (CAT) is a yellow decal that means your car is generally not used between the overnight hours of 1 to 5 a.m. If the NYPD sees a car with that sticker on the road between those hours, they have permission to question the driver to ensure ownership.
There is a CAT Program for Commuters which operates under the same principle, except that the yellow sticker has a black border which means that the car is generally parked during the daytime hours of 10 a.m. and 4 p.m.
I know what you are thinking: What if you are off or on vacation and you are driving around and get stopped by the NYPD? You show them your ID and carry on, secure in the knowledge that had your car been stolen it would now be in the process of being returned to you.
Help End Auto Theft (HEAT) is a program predicated on the sad statistic that the majority of persons arrested for auto theft are less than 25 years of age. To register in the HEAT program, you must be over 40 years old, and you will sign a waiver that no persons under 25 will be driving your vehicle and you will get a bright red decal.
If a young person is driving a car with that sticker, it will indicate to the NYPD that it may be a stolen vehicle and that they should pull it over and question the driver.
In addition to these anti-theft measures, you will also be able to make an appointment to get your vehicle etched. It's a fast and easy process and the 102nd Precinct will make an appointment to come to your house and etch your VIN (vehicle identification number) on all of your automobile's windows.
This is a highly successful program that not only helps the NYPD return stolen cars and parts to their rightful owners, it also serves to deter car thieves. These thieves are smart enough to look for a VIN etching and, once they spot it, are very likely to move on to a vehicle which hasn't been marked.
If you have any questions, feel free to drop us a line at firstname.lastname@example.com or call (718) 296-3735 and leave a message.


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More foods can affect your health or your baby's than you might realize. Find out what foods to avoid during pregnancy.
You want what's best for your baby. That's why you add sliced fruit to your fortified breakfast cereal, top your salads with chickpeas and snack on almonds. But do you know what foods to avoid during pregnancy? Here's help understanding pregnancy nutrition basics.
Seafood can be a great source of protein, and the omega-3 fatty acids in many fish can promote your baby's brain and eye development. However, some fish and shellfish contain potentially dangerous levels of mercury. Too much mercury could harm your baby's developing nervous system.
The bigger and older the fish is, the more mercury it's likely to contain. The Food and Drug Administration (FDA) encourages pregnant women to avoid:
So what's safe? Some types of seafood contain little mercury. The 2015-2020 Dietary Guidelines for Americans recommend 8 to 12 ounces — two or three servings — of seafood a week for pregnant women. Consider:
However, limit white (albacore) tuna to 6 ounces (170 grams) a week.
To avoid harmful bacteria or viruses in seafood:
During pregnancy, you're at increased risk of bacterial food poisoning. Your reaction might be more severe than if you weren't pregnant. Rarely, food poisoning affects the baby, too.
To prevent foodborne illness:
Many low-fat dairy products — such as skim milk, mozzarella cheese and cottage cheese — can be a healthy part of your diet. Anything containing unpasteurized milk, however, is a no-no. These products could lead to foodborne illness. Avoid soft cheeses, such as Brie, feta and blue cheese, unless they are clearly labeled as being pasteurized or made with pasteurized milk. Also, avoid drinking unpasteurized juice.
To eliminate any harmful bacteria, thoroughly wash all raw fruits and vegetables. Avoid raw sprouts of any kind — including alfalfa, clover, radish and mung bean — which also might contain disease-causing bacteria. Be sure to cook sprouts thoroughly.
While caffeine can cross the placenta, the effects on your baby aren't clear. To be safe, your health care provider might recommend limiting the amount of caffeine in your diet to less than 200 milligrams a day during pregnancy. For perspective, an 8-ounce (237-milliliter) cup of brewed coffee contains about 95 milligrams of caffeine, an 8-ounce (237-milliliter) cup of brewed tea contains about 47 milligrams and a 12-ounce (355-milliliter) caffeinated cola contains about 33 milligrams.
There's little data on the effects of specific herbs on developing babies. As a result, avoid drinking herbal tea unless your health care provider says it's OK — even the types of herbal tea marketed specifically to pregnant women.
No level of alcohol has been proved safe during pregnancy. The safest bet is to avoid alcohol entirely.
Consider the risks. Mothers who drink alcohol have a higher risk of miscarriage and stillbirth. Too much alcohol during pregnancy can result in fetal alcohol syndrome, which can cause facial deformities and intellectual disability.
If you're concerned about alcohol you drank before you knew you were pregnant or you think you need help to stop drinking, consult your health care provider.
Original article: https://www.mayoclinic.org/healthy-lifestyle/pregnancy-week-by-week/in-depth/pregnancy-nutrition/art-20043844
Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.
Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.


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My Facebook newsfeed is alight with lively celebration of Marissa Mayer, both because she is a young, talented woman and because she announced her pregnancy on the same day as the Yahoo CEO news.
As the post below notes, she is giving YAHOO a whole new meaning for women looking for relatable, or at least inspiring, role models.
Out of these public and private media Marissa celebrations, it seems a new zeitgeist is developing around the importance of women with topics as diverse as the obvious- Influential Women in Silicon Valley - to the should be obvious- Why Women Matter Online
She joins the ranks of the all too limited women running Fortune 500 companies. According to Catalyst, a NYC nonprofit that researches women's issues, Marissa becomes the record 20th female CEO of fortune 500 companies.
Whether Marissa likes it or not, the pregnancy news was truly the icing on an already great success story.
Women are still digesting how to have an impact after the recent Anne-Marie Slaughter article. Many were depressed by the inertia of the industries in which they work or hope to work. I for one was inspired, because as a thirtysomething woman in an executive position, I felt I could start making a difference. I was left asking questions such as- What if every woman moved by this article came up with structural improvements for the world they influence? Are there small changes to norms and scheduling that could go a long way in each of my talented friends' professions?
Whether Marissa realizes it or not, the way she treats maternity leave will serve as an example or an anti-example for all woman looking for a path, for those women who do not want "to gap" their ambition, but also want to enjoy being a parent.
To be sure, Marissa is not a typical woman and her dilemma is not an easy one. But, I am a big believer that macro change is most likely to have an impact by starting at the top, with the most visible examples, however unusual the circumstances. The good news is that gender diversity is tied to economic results.
McKinsey recently put out a 2010 study called Women Matter that suggests companies that have women most strongly represented on the board or senior positions perform the best. See the data below in which McKinsey looked at European companies across 6 countries, comparing the performance of companies that fell into the top-quartile in terms of share of women in executive committee roles to all male executive committees. Companies with the highest share of women outperform companies with no women when looking at both return on equity and operating margin.
I have personally taken two maternity leaves, one while co-heading the Mergers & Acquisitions group for IAC and one while running Urbanspoon, Citysearch and Insider Pages, a collection of consumer internet businesses that serve 50 million unique users a month and employ ~100 people.
Figuring out how to strike a balance was a struggle for each. While I was out, there were mistakes made, but it also gave my direct reports a chance to execute against a plan we put in place prior. Maternity leave creates opportunity for senior leaders to manage their business through time-lapse photography. After a limited time of light management it is much easier to tell who moved through walls to execute and who did not.
As I was struggling to determine the best course for me, my family and my businesses, I received unsolicited advice from many women who appreciated or regretted the way they took their leave. Much of the regret advice came with warnings such as "She was a hard worker" never graces anyone's gravestone.
With the benefit of time and distance, my unsolicited advice to Marissa:
Take a real maternity leave of some variety! Or at the very least, do not downplay its importance. Celebrate your role as the first ever pregnant CEO of a Fortune 500 company. While Yahoo may end up as the greatest Internet turnaround of all time or it may limp along, 90 days will not ultimately determine its outcome. It will change you and may even make you better with the rare opportunity to gain perspective from the side of a crib.
Specifically, put together 12 week plans with clear defined metrics for each of your teams while you are on leave. Create rules by which your team should reach out to you and you will respond to emails. For example, "timely" goes for topics such as a decision around a critical partnership that may lock you up in exclusivity for a year. Generally speaking, any major decision (define major by a metric like level of revenue or traffic) that cannot be changed when you return should run by you. Focus your time and attention on the big needle movers- key hires and key strategy decisions. If your brain has to work well early in the morning, meet your friend the coffee pot or ask your husband to take the nighttime feedings.
Marissa, you have an opportunity to create an even greater legacy to women and men everywhere by building a culture that finds the balance between business achievement and emotional satisfaction. Yahoo is your company. You are a rock star. Do not be afraid to be different and change the world. I look forward to reading your story to my grandkids someday.
Don't Miss: The Truth About Marissa Mayer: She Has Two Contrasting Reputations
See also: The Impressive Career Of Yahoo's New CEO, Marissa Mayer >
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The name changes now coming into effect in Taiwan reflect an increasing approval of "Taiwan identity" rather than "Taiwan independence," despite the suggestions made in the disapproving rhetoric of the US, political analysts have said.
Last week, President Chen Shui-bian (陳水扁) pledged to change the names of state-owned enterprises, the nation's embassies and overseas representative offices and other laws and regulations.
As a result, Chunghwa Post Co (
After the pan-blue camp voiced its opposition to the name changes, on Saturday US Department of State spokesman Sean McCormack said: "We do not support administrative steps by the Taiwan authorities that would appear to change Taiwan's status unilaterally or move toward independence. The United States does not, for instance, support changes in terminology for entities administered by the Taiwan authorities."
US comments
The US comments on changing the names reflected remarks made by Chinese Nationalist Party (KMT) Chairman Ma Ying-jeou (
But political analysts said Ma overreacted and over-interpreted the name change issue.
"The US' reaction might be a little bit disturbing to the name-change bid but it did not oppose it directly because it does not violate President Chen's guarantees in his 2000 inaugural address," said Lo Chih-cheng (羅致政), the chairman of Soochow University's political science department.
The Democratic Progressive Party (DPP) and Chen's administration have prepared for the name changes for a long period of time and did not suddenly bring the issue up, Lo said.
"You will find the name-change campaign is actually linked with other issues of transitional justice and it does not necessarily relate to the concept of `Taiwan independence,'" Lo said.
"Taiwan identity" and "Taiwan independence" are two different matters, Lo said.
"For the people of Taiwan, pursing the recognition of `Taiwan identity' has been brought about by Taiwan's democratic development and the name change issue is emerging in this circumstance," he said.
Polls conducted by the government and by outside pollsters over the past decade show that a steadily increasing number of people recognize themselves as "Taiwanese" instead of "Chinese."
"I do not think the US can deny the increase of `Taiwan identity' because it is upheld by public opinion," Lo said. "The concept of independence is political, but the concept of having a clear identity is a natural process of democracy."
With the rise of "Taiwan identity," changing the names is an irresistible trend and will not go backwards, he said.
Bilateral negotiations and communication will be required to change the names of the nation's overseas embassies and representative offices, and the government will not seek to make immediate, unilateral changes.
The signs in Taiwan's embassies now display the word "Taiwan" in parenthesis under "Republic of China," Taiwan's official national title.
Hsu Yung-ming (


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Bush Fuel Economy Plan Rejected By The Courts
The Bush administrations fuel economy plan was rejected by 9th U.S. Circuit Court of Appeals, Thursday. The court ruled that National Highway Traffic Safety Administration "failed to address why the so-called light trucks are allowed to pollute more than passenger cars and didn't properly assess greenhouse gas emissions when it set new minimum miles-per-gallon requirements for models in 2008 to 2011," according to the Associated Press.
The court ordered the White House to examine why it continues to consider light trucks differently than cars. Regulators made a distinction between cars and light trucks decades ago when most trucks were used for commercial purposes.
NHTSA had argued that it considered the intent of the manufacturer in making light trucks, rather than their actual highway use, in developing the new fuel standards.
"But this overlooks the fact that many light trucks today are manufactured primarily for transporting passengers," Fletcher wrote for the three-judge panel.
Fletcher also wrote that the administration failed to consider the benefit to reducing greenhouse gas emissions.
"It did, however, include an analysis of the employment and sales impacts of more stringent standards on manufacturers," Fletcher wrote.
The court also took the administration to task for refusing to include in the new standards trucks weighing more than 8,500 pounds, a class that includes the Hummer H2, Ford F250 and other popular large vehicles.
The court ordered NHTSA to develop fuel standards for these large trucks or give a better reason than the agency's argument that it has never regulated those large trucks and that more testing needs to be done.
"This historic ruling vindicates our fight against fuel economy standards that are a complete sham and a gift to the auto industry," said Connecticut Attorney General Richard Blumenthal, who also joined the lawsuit.
Oh no, someone has irritated Richard Blumenthal. Now their destruction is assured.
Court Rebukes Bush Fuel Economy Plan [AP]
(Photo:George E. Norkus)
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A-Z of LECTURES and CATEGORIES
Cambridge Science Festival
Listing Details
'Gives the public the opportunity to explore Cambridge Science ... Each year, the Festival welcomes visitors to hundreds of events and receives extensive national and local media coverage. Over 170 event coordinators organise talks, interactive demonstrations, hands-on activities, film showings and debates with the assistance of around 1,000 staff and students from departments and organisations across the University and research institutions, charities and industry in the eastern region.'
University of Cambridge, The Old Schools, Trinity Lane
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Capesante Risotte ai Funghi
A spectacular Summer dish, creamy risotto made with diced onions, sauteed portabello mushrooms and scallops drenched in butter and garlic. The risotto was cooked perfectly which takes at least 20 minutes and the mushrooms had such a meaty flavor. I then heated up a small pan, melted butter added a few garlic cloves and sauteed the scallops. The smells were like we were at the Sea.
Scallop Mushroom Risotto
8 large scallops
1 large portobello mushroom
2 cups Arborio rice
4 cups vegetable broth
1/2 onion, diced
1/2 cup parmigiano cheese, grated
4 tablespoons butter
olive oil
4 garlic cloves
1 tablespoon fresh parsley, chopped
salt and pepper
In a large pan heat 2 tablespoons butter and 1 tablespoon olive oil, saute onions for a few minutes add rice and coat with butter and onions. Toast the rice 3 or 4 minutes, add broth one ladle at a time. Let the broth absorb into the rice before adding more. This should take about 20 minutes it wil be al dente, add parmigiano.
In a frying pan heat butter, slice mushrooms and saute on each side add salt and pepper, set aside. In a small frying pan add 2 tablespoons butter and 3 or 4 garlic cloves get it hot add scallops and don't move for 2 minutes flip over and cook another minute or so.
Arrange rice on plate top with sliced mushrooms and a scallop or two. Sprinkle fresh parsley and serve, serves four.
Ricette by Chef Chuck's Cucina


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GPSC PDF Module 6 Geography
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GPSC Module 6 Geography
Medium of All Notes and Tests furnished by PSCNOTES.COM is English Only
Further all individual modules are in PDF Format, ie digital files only. Product untill specifically mention as printed/hardcopy are PDF or digital format only.
For any doubt kindly contact us


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Apologies if this is really obvious but I have tried a google search for an answer but can't seem to find one.
What I essentially want to do is define a class say MainApp, which would control the program execution with a set of methods such as MainApp::draw(), MainApp::update() and MainApp::resize() which would draw and handle mouse and keyboard input and changes to the window. I've only ever set up OpenGL using the glutDisplayFunc(display), glutKeyboardFunc(keyboard), and glutReshapeFunc(reshape) functions in main() and don't know how to move these into class methods?
I did find some frameworks available but they seemed to be more functions to control OpenGL and not a class in their own right.
Any help would be much appreciated.


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Italian Easter Pie
Every Easter my mom, grandma and aunts would make two easter pies, one a meat and ricotta filled pie and a second one, sweet ricotta and rice pie. In the book, In Nonna's Kitchen by Carol Field there is a recipe for Pizza Rustica Neopolitan. It is very much like the meat filled Easter pie of my childhood. I tried the recipe today for the first time. The pastry crust was a bit strange for me as it was made with olive oil, flour, salt and water, I'd never made a crust from those ingredients before. For the filling, I first made some whole milk ricotta and then added eggs, mortadella, salami, homemade romano cheese and parmesan along with fresh ground nutmeg and black pepper. Baked in a spring form pan, this Easter pie came out well. I can't wait to taste it tomorrow as part of our lunch.


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Figure Out Facebook Live Workbook & Video Lessons
Don't know what to go live about?
Organic reach on Facebook is pathetic – right?!
Take it from me, a former Facebook employee: the best chance you have at making organic reach work for you is to build in a consistent Facebook Live strategy – but it can be easy to feel overwhelmed and think that you don't have anything to talk about… I'm here to tell you, you have a LOT of value to offer and your followers WANT to hear from you!
Get my free workbook and then grab the super-affordable Figure Out Facebook Live video lessons, which walk you page-by-page through the workbook so that you can create a steady flow of content ideas for your Facebook Live video strategy AND the building blocks for some ah-mazing Video View Ads (which are the perfect first step when building out your Paid Facebook Marketing strategy)!
1 review for Figure Out Facebook Live Workbook & Video Lessons
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Abi –
I got this a while ago and went back to the workbook many times to figure out my plan for doing a live. I wanted to be sure that I don't ramble on live Fb, and this really helped me.
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Google and Square be forewarned: Wal-Mart wants to open in your virtual neighborhood.
The nation's largest retailer is amongst two dozen retailers reportedly looking to get into the mobile payment race, according to The Wall Street Journal.
The growing multi-billion dollar market, that allows shoppers to use their phones to make payments, is currently dominated by the likes of Google, Square and PayPal.
The newspaper reports that the likes of Wal-Mart and Target are looking to expand into the arena to attract younger customers and to increase customer loyalty.
It is also a way to get better analytics on customers and their shopping habits, as products like Square are already offering its users.


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Laboratory pressure reactor system
Reactor volume: 0.25 - 20 liter
Pressure: 60 bar
Temperature: 250°C
Material: Borosilicate glass, stainless steel, Hastelloy
- This system was replaced with the following products:
- ecoclave
- polyclave
- versoclave
- kiloclave
- Spare parts for the BEP 280 are still available
This multipurpose pressure reactor system is designed for the use of interchangeable glass - and steel pressure vessels. Safety features guarantee safe reactions under pressure.
The glass reactors ensure high resistance against acids, while allowing visual process control and monitoring. This is also possible under high pressure by using steel pressure vessels with sight glasses. Various low to high torque magnetic drives ensure efficient mixing and stirring low to high viscosity process media as well as excellent heat transfer.
The modular setup of the BEP280 system allows changing or upgrading for new tasks at any time.
A wide range of accessories for feeding of liquids / solids / gas and others like catalyst baskets, etc. are available – talk to us to define the right setup for your specific need.


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Trauma in peace and war
Toys used for Margaret Lowenfled's 'World Technique' therapy, England, 1920-1970
Not just for soldiers
Post-traumatic stress disorder (PTSD) has attracted much popular and medical attention in recent decades. It is most often associated with soldiers returned from combat. PTSD is however also found in survivors of sexual abuse, torture and genocide. It can often lead to depression, aggression or suicide.
Trauma, defined as a emotionally scarring experience, is at the heart of PTSD. Until the early 1900s, trauma was the domain of surgeons, not psychotherapists. It meant a violent physical blow to the body, such as a gunshot or a fall from a horse. The subsequent shift in emphasis from the body to the mind involved combat veterans, people caught in the crossfire, women diagnosed with hysteria, and people hurt in railway or industrial accidents.
Spinal trauma or nerve disease?
Victims of railway accidents in Victorian Britain often reported flashbacks and debilitating anxiety or nerves. They were diagnosed with 'railway spine', physical trauma to the nerves in the spine. French neurologist Jean-Martin Charcot rejected the idea. He argued the physical jolt disrupted the nervous system, exposing an inherited neurological disease that the body had previously masked. This underlying disease, Charcot argued, was hysteria. Charcot's theory explained why some victims of railway accidents survived with their nerves intact while others displayed symptoms typical of hysteria including fatigue, trembling, shortness of breath, anxiety and paralysis. It also explained why symptoms of railway spine, like symptoms of hysteria, often disappeared under hypnosis.
Though Charcot's theory was disputed and soon abandoned, the medical debate had economic and social consequences. Nervous trauma from industrial accidents figured alongside neurasthenia and hysteria in German political debates about degeneration. Germany pioneered workers' compensation in the 1880s, but critics of this welfare system alleged that increased nerve-related compensation claims proved the working classes were degenerating. German insurance boards consequently rejected the pension claims of trauma survivors. Some survivors argued they had been traumatised twice: by the accident and then by years spent appealing.
Shell shock and related diagnoses
The term 'shell shock' was coined by a British physician during the First World War and has come to be almost synonymous with PTSD. The diagnosis, however, originally applied only to those cases where soldiers survived an explosion apparently unharmed, yet soon after showed symptoms of spinal or nerve damage. This idea was modelled on railway spine.
Soldiers with symptoms not linked to physical nerve trauma received other diagnoses. These often depended on the severity of their symptoms and sometimes on the soldier's socioeconomic class. The 'walking wounded' and officers tended to be diagnosed with neurasthenia or nervous breakdown. More severe cases were often labelled hysteria. Many German military physicians interpreted soldiers' debilitating nervous symptoms as a consequence of degeneration rather than trauma. The soldier was blamed, not the situation.
Psychiatrists and neurologists in the First World War used a range of therapies to return traumatized men to the front. These included medical methods such as hypnosis, reflecting Charcot's influence, and electrotherapy. Non-medical methods included persuasion, electric shock and psychological coercion. However, many men were too scarred to respond, and often languished in asylums.
The road to PTSD
British physician William Rivers pioneered an experimental psychotherapy during the First World War. It was inspired by Sigmund Freud's work in Vienna with women diagnosed with hysteria. Freud observed certain symptoms of nervous illness were caused by memories too difficult to bear. Rivers encouraged emotionally wounded soldiers to share their memories, nightmares and fears - they should 'talk through' emotional traumas to move beyond them.
Emotional understanding of trauma pioneered by Freud dominated military and civilian medicine during the Second World War. Military psychiatrists developed the slogan 'every man has his breaking point'. This attitude reduced the stigma surrounding battlefield breakdowns and helped traumatised soldiers adapt to peacetime life. The focus was on traumatic combat rather than weakness or disease within the soldier's nervous system.
Post-war developments in the psychotherapy of trauma resulted from work with people traumatized in Nazi death camps and child abuse survivors. London paediatrician Margaret Lowenfeld developed several influential non-verbal therapies. She used coloured tiles and small toys to help children express emotions they did not have the words to describe. Other developments came through work with soldiers in later wars and civilians uprooted by such conflicts. The 1980 revision of the American Diagnostic and Statistical Manual (DSM), published soon after the Vietnam War, codified the diagnosis today called PTSD. Both soldiers and civilians played important roles in its history.
Related Themes and Topics
Related Objects
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Related links
Techniques and Technologies:
M Lowenfeld, The World Technique (George Allen & Unwin, 1979)
B Shephard, A War of Nerves - Soldiers and Psychiatrists 1914-1994 (Pimlico, 2002)
A Young, The Harmony of Illusions: Inventing Post-Traumatic Stress Disorder (Princeton, NJ: Princeton University Press, 1997)
M S Micale and P Lerner, Traumatic Pasts: History, Psychiatry, and Trauma in the Modern Age, 1870-1930 (Cambridge: CUP, 2001)


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Indianapolis: Paul George scored 12 of his 20 points in the third quarter, Evan Turner had 13 points in his Pacers debut, and Indiana beat the Los Angeles Lakers 118-98 on Tuesday night. Indiana improved its league-leading record to 43-13.
Kent Bazemore finished with a career-high 23 points and Jodie Meeks added 15 for the Lakers (19-38), who have the worst record in the West. The loss also ended Los Angeles' three-game winning streak at Bankers Life Fieldhouse.
The Lakers stayed closer than expected through the first quarters and trailed just 59-58 early in the third.
But George then scored 10 points in a decisive 14-5 spurt that gave Indiana an 80-68 lead with 2:58 to go in the period. The Pacers finished the quarter on an 11-2 run to make it 91-70, and the Lakers couldn't get closer than 19 the rest of the way.
It was a huge night for George and Indiana's continually evolving bench.
George had seven rebounds and six assists despite spending the entire fourth quarter on the bench with most of Indiana's starters. David West had 11 points and 12 rebounds, Roy Hibbert finished with 10 points, six rebounds and four blocks, and the Pacers got 50 points from the bench with their newest player, Turner, leading the way.
Lavoy Allen, who came with Turner from Philadelphia last Thursday in a trade deadline deal, played the final four minutes. Andrew Bynum, who signed with Indiana on Feb. 1, did not play against one of his former teams and still has not suited up for Indiana.
It didn't matter on Tuesday, even on a night that Bazemore produced a career-high total for the third straight game. He's had career bests in all three games since being traded to Los Angeles from Golden State.
He was one of the big reasons Indiana struggled to pull away early.
After trailing 57-54 at the half, the Lakers got as close as 59-58 when Pau Gasol hit a 15-foot jumper early in the third.
Then George and Co reasserted themselves and never gave the Lakers another chance.
West's tip-in and five straight points from George Hill made it 66-61. George followed that with 10 points in the big run that finally gave Indiana an 80-66 lead.
They weren't even close to being finished. Indiana closed the quarter on an 11-2 spurt and when C.J. Watson made a 3-pointer with 2 seconds left, the Pacers led 91-70.
Indiana fell one point short of matching a season-best point total and is now 27-3 at home this season.
Indiana 118, L.A. Lakers 98
Washington 115, Orlando 106
Toronto 99, Cleveland 93
Chicago 107, Atlanta 103
Minnesota 110, Phoenix 101
Portland 100, Denver 95
Houston 129, Sacramento 103


text: Yasemin Kaçkar-Demirel captures the emotional aspects of architecture through chaotic, fragmented cityscapes. Using inks, watercolors, pastels, resins, and paints, Kaçkar-Demirel reveals the essence of a scene through color, shape, and pattern. She removes cityscapes from their original contexts and reconstructs them to build a narrative, enhancing and embodying the memories associated with such places. In warping and destroying the physicality of specific locations, she reimagines and enhances their emotional and psychological associations and crafts new identities. Her scenes achieve harmony and equilibrium through a balance of opposites; she finds comfort amid insecurity, order amid chaos, and representation amid abstraction. In doing so, she aims to create a fluid and spontaneous viewing experience that allows for personal engagement and subjective associations.


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Remember, you heard it first here. The next new food fad? My money's on muscadines. Pretty soon you'll see muscadine tablets, juices, extracts, and more. Why? Perhaps you've heard of the so-called French Paradox -- the conundrum that the French have a much lower incidence of heart disease than would be expected considering their rich cuisine? (How can they eat those delicious cream sauces and decadent pastries and still be healthy?) It's all about the wine, or at least that's the current thinking. More specifically, it's about resveratrol, a potent antioxidant found in red wine. And although some of us are happy sipping an occasional merlot -- for its health benefits, of course -- researchers have been looking for other, non-alcoholic sources of resveratrol, and they've found it in our own backyard: the muscadine grape.
Muscadines (Vitis rotundifolia) are native to the southeastern U.S., where they've been cultivated for hundreds of years. Unlike other Vitis species, muscadines thrive in the heat and humidity. They don't like the cold though, and suffer in regions where winter temperatures linger below 10 degrees F. The vines are vigorous, reaching 100 feet in length in the wild, so growing muscadines isn't for the faint of heart, or the faint of trellis. The fruits are round and 1 to 1-1/2 inches in diameter -- "about the size of a hog's eye" according to locals.
Muscadine fruit is borne in loose clusters. Unlike table grapes, muscadines have a thick, tough skin and contain hard seeds. When I first moved here a farmer's market vendor gave me one to try, and, trying to be polite, I ate the whole thing. Now I know that most people nip a hole in the skin, then suck out the pulp and spit out the seeds.
The fruits range in color from light greenish bronze to purple to almost black. Light-colored muscadines are often called scuppernongs. The origin of this name is sketchy. One account states that a vine bearing light-colored fruits was discovered and propagated by cuttings. (The vine was probably a sport -- a unique plant arising from a spontaneous mutation -- of a dark-fruited plant.) During the 17th and 18th centuries, additional cuttings were placed into production around a small town named Scuppernong in Washington County, North Carolina, hence the common name.
Today, the light-colored muscadines grown commercially are cultivated varieties, rather than cuttings from this original plant, but most people still call them scuppernongs to distinguish them from their dark-fruited cousins.
Growing Challenges
Although those of you in the warmer parts of our region can grow muscadines in your backyard, that doesn't necessarily mean you should. Left unchecked, the vines will get frighteningly big (think Little Shop of Horrors), so you'll need to follow a rigorous pruning regimen to keep them manageable.
Vines should be set about 20 feet apart in rows; spacing between rows is up to you. The vines can then be trained to a very sturdy single wire trellis system set at a height of 5 or 6 feet to facilitate pruning and harvesting. Some types of muscadines are perfect-flowered, meaning the flowers have both male and female parts, and are self-fertile. However, some of the more commonly available varieties bear flowers with only female parts, so a perfect-flowered variety must be planted nearby if you want fruit. Fortunately, the plants are generally pest-free, with the exception of Japanese beetles, which can defoliate the vines.
Those of you unable or unwilling to grow your own muscadines, take heart. The fruit is readily available in September and October in grocery stores and some farmer's markets. You can eat it fresh or make jams, jellies, and pies. Or wine. In a recent study, funded in part by the National Institutes of Health, researchers found that muscadine wines can contain up to seven times more resveratrol than regular wines. Even more impressive, they found that the fruits themselves have up to 40 times the amount of resveratrol as regular table grapes. Plus they contain the highest levels of antioxidants and ellagic acid of any other fruit tested, far more than blueberries, a nutritional powerhouse. (Ellagic acid is thought to help prevent abnormal cell growth.) And the levels of antioxidants weren't just a little higher, they were much higher.
I'm quite sure that you'll soon see muscadine juice next to pomegranate, blueberry, and cranberry juices -- all marketed as antioxidant-rich. In the meantime, I'm going to look for a muscadine vineyard to invest in.