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Shoppers Drug Mart Enters Into Agreement to Acquire Paragon Pharmacies
May 22, 2012, 18:08 ET
TORONTO, May 22, 2012 /CNW/ - Shoppers Drug Mart Corporation (TSX:SC) ("Shoppers" or the "Company") today announced that it has entered into a definitive agreement with Paragon Pharmacies Limited (TSXV:PGN.V) ("Paragon") pursuant to which Shoppers has agreed to purchase from Paragon 19 retail pharmacies and three central fill pharmacies located in British Columbia, Alberta and Manitoba for a purchase price of approximately $75 million in cash, subject to certain adjustments. The completion of the transaction is subject to the approval of Paragon's shareholders, acceptance by the TSX Venture Exchange and certain other customary closing conditions. The parties anticipate that the transaction will close in the third quarter of 2012.
The acquisition of the Paragon retail pharmacies, along with the central fill locations that service the long-term care market, represents a meaningful expansion of Shoppers' retail presence in western Canada and provides a platform for the Company's MediSystem Technologies Inc. business to enter the British Columbia and Manitoba markets.
"This acquisition is a very good fit for Shoppers Drug Mart and is consistent with our stated growth objectives in retail pharmacy and long-term care," said Domenic Pilla, President and Chief Executive Officer of Shoppers. "We look forward to welcoming the pharmacists and employees of Paragon to the Shoppers family and together, continuing to meet the needs of the patients and customers they serve."
Summary of the Transaction
On May 22, 2012, Shoppers and Paragon entered into an asset purchase agreement setting out the terms and conditions pursuant to which Shoppers has agreed to purchase from Paragon substantially all of the assets of Paragon which consist of its chain of 19 retail pharmacies and three central fill pharmacies in British Columbia, Alberta and Manitoba. Shoppers has agreed to purchase the assets for approximately $75 million in cash, subject to certain adjustments. Among other things, Paragon has agreed to provide Shoppers with a period of 20 business days to allow Shoppers to conduct its confirmatory due diligence. During that time, Shoppers may propose one or more purchase price adjustments to reflect the results of its due diligence as it affects adjusted store operating income of Paragon, subject to a maximum of $7 million in aggregate reductions.
The transaction must be approved by at least 66⅔% of the votes cast by the shareholders of Paragon in person or by proxy at a special meeting of Paragon shareholders expected to take place in July 2012. The asset purchase agreement has been unanimously approved by both companies' boards of directors and the transaction is expected to be completed in the third quarter of 2012. Concurrent with the entering into of the asset purchase agreement, Shoppers entered into a voting support agreement with Canterbury Park Capital L.P. and Canterbury Park Capital (U.S.) L.P. (together, "Canterbury"), pursuant to which Canterbury has irrevocably agreed to support the proposed transaction and vote all of the common shares of Paragon that Canterbury owns in favour of the transaction. Canterbury beneficially owns and controls 68,271,783 common shares of Paragon representing approximately 77% of the issued and outstanding common shares of Paragon.
About Shoppers Drug Mart Corporation
Shoppers Drug Mart Corporation is one of the most recognized and trusted names in Canadian retailing. The Company is the licensor of full-service retail drug stores operating under the name Shoppers Drug Mart (Pharmaprix in Québec). With more than 1,206 Shoppers Drug Mart and Pharmaprix stores operating in prime locations in each province and two territories, the Company is one of the most convenient retailers in Canada. The Company also licenses or owns 57 medical clinic pharmacies operating under the name Shoppers Simply Pharmacy (Pharmaprix Simplement Santé in Québec) and eight luxury beauty destinations operating as Murale. As well, the Company owns and operates 63 Shoppers Home Health Care stores, making it the largest Canadian retailer of home health care products and services. In addition to its retail store network, the Company owns Shoppers Drug Mart Specialty Health Network Inc., a provider of specialty drug distribution, pharmacy and comprehensive patient support services; and MediSystem Technologies Inc., a provider of pharmaceutical products and services to long-term care facilities.
For more information, visit www.shoppersdrugmart.ca.
Cautionary Statement on Forward-Looking Information
This news release contains forward-looking information and statements which constitute "forward-looking information" under Canadian securities law and which may be material regarding, among other things, Shoppers' beliefs, plans, objectives, strategies, estimates, intentions and expectations. These include, but are not limited to, statements with respect to the completion of the proposed transaction. Forward-looking information and statements are typically identified by words such as "anticipate", "believe", "expect", "estimate", "forecast", "goal", "intend", "plan", "will", "may", "should", "could" and similar expressions.
The forward-looking information and statements contained herein are based on certain factors and assumptions, certain of which appear proximate to the applicable forward-looking information and statements contained herein. Inherent in the forward-looking information and statements are known and unknown risks, uncertainties and other factors beyond Shoppers' ability to control or predict, which give rise to the possibility that Shoppers' predictions, forecasts, expectations or conclusions will not prove to be accurate, that Shoppers' assumptions may not be correct and that Shoppers' plans, objectives and statements will not be achieved. Actual results or developments may differ materially from those contemplated by the forward-looking information and statements.
Certain of these risks, factors, estimates and assumptions are described in more detail in Shoppers' most recently filed Annual Information Form in the section entitled "Risk Factors", and in the "Risks and Risk Management" and "Risks Associated With Financial Instruments" sections of Shoppers' most recently filed annual and quarterly Management's Discussion and Analysis for the 52 week period ended December 31, 2011 and the 12 week period ended March 24, 2012, respectively, to which readers are referred and which are incorporated by reference in this news release. In addition, all forward-looking statements made in this news release are qualified by the full "Caution Regarding Forward-Looking Information and Statements" in such Annual Information Form and the "Forward-Looking Information and Statements" in such Management's Discussion and Analysis. These risks, factors, estimates and assumptions are not exhaustive. Shoppers disclaims any intention or obligation to update or revise any forward-looking statements whether as a result of new information, future events or otherwise, or to explain any material difference between subsequent actual events and such forward-looking statements, except to the extent required by applicable law.
For further information:
Media Contact:
Tammy Smitham
Director, Communications & Corporate Affairs
(416) 490-2892, or
(416) 493-1220, ext. 5500
Investor Relations:
(416) 493-1220, ext. 5678


text:
View RequestRequest a quote for this item and we'll contact you as soon as possible to discuss options, finishes and pricing.
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Bix Tables by Coalesse
Crafted to integrate seamlessly into collaborative offices and work environments, Bix Tables and Side Tables support the many needs of the modern workplace.
A refined, inclusive set of tables designed to complement the Bix range of seats, Bix offers lounge-based work settings perfect for encouraging collaboration and social connection. Crafted for seamless integration with the many changing needs of the modern workplace.
- Upholstery edge detail
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- Optional Power/Voice/Data access and modules
Product Range
For more product details about Bix Tables, please visit coalesse.com

subset: commoncrawl


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Check out this animation by YouTube user RyleyAndFriends. It redoes Adventure Time's intro, but in 3D. It's great.
I should catch up on Adventure Time. Not this weekend though. This weekend is for conventions and crazy adventures that I'll get to write about next week. I'm excited. I'd tell you what those are, but I don't want to spoil it.
What about you, what's waiting for you this weekend? Any plans? Feel free to talk about that, or Adventure Time, or just about anything else here or in the Talk Amongst Yourselves forum.
See you next week!
Adventure Time Theme In 3D Animation!! - Ryley Swan [RyleyAndFriends via Reddit]


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Marilyn Monroe was never on time, which is apt, given that her image has become timeless.
It's been fifty years since her death, yet Marilyn's beauty still prevails. We all know her iconic look too well; platinum hair, sultry eyes, scarlet lips, that beauty spot. Indeed, she's the epitome of old Hollywood glamour, and I sincerely doubt she'll ever go out of fashion.
So, it comes as no great surprise to me that MAC cosmetics' latest collection is dedicated to and inspired by the late actress. Simply named Marilyn Monroe by MAC, the limited-edition collection was released on October 4th and includes a rich variety of beauty products, all of which are in keeping with Marilyn's signature style.
A few products have already caught my eye, in particular the Marilyn Monroe Lipstick which comes in a range of bold shades. Each shade channels Marilyn's red-hot appeal, and serves as a keen reminder of her luscious, megawatt smile. The eye products look rather dreamy too; I bet the False Lashes Extreme Black Mascara and Penultimate Eyeliner both do a fine job of recreating Marilyn's sleepy, feline eyes.
The entire collection looks gorgeous, but what I particularly like about it (aside from the kitsch packaging, of course) is the fact that each shade has been given its own quaint, Marilyn-themed name. My personal favourites are: "Vintage Vamp", "Rich, rich, rich", and "Charmed I'm sure". How very Marilyn!
I'm determined to get my hands on at least one Marilyn Monroe by MAC product before the collection is discontinued. Though this may prove to be a challenge; such is Marilyn's everlasting appeal that half of the products on MAC's website are already sold out!
For more on Marilyn Monroe by Yesterface, have a look at this article and my Marilyn Monroe makeup tutorial.


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Warner Bros. is officially launching their awards season campaign for The Dark Knight Rises, and it is not out of the question that Christopher Nolan's concluding chapter to the Dark Knight Trilogy could be in the race for the biggest award, the Oscar.
The question is: does the movie deserve to win? We look back on the merits (and deficiencies) of Nolan's final Batman opus - but if you've already made up your own mind, feel free to hop on down to our poll at the bottom and cast your vote.
In our own Dark Knight Rises review, we gave the film a 4 out of 5 star score, based on the level of technique in Nolan's directing, as well as cinematographer Wally Pfister's excellent shot composition. Add to that standout performances from franchise star Christian Bale, and strong debuts from franchise newcomers Joseph Gordon-Levitt, Anne Hathaway and Tom Hardy as Bane - perhaps the most parodied film character of 2012.
Then again, time does have a habit of changing things: looking back now, it's clear that while Dark Knight Rises is still a great film, and one of the better Batman stories ever told, compared to the rest of the Nolan Bat-films it is arguably (key word: "arguably") the weakest entry in a very strong trilogy. (As discussed in depth (and infamy) on our Dark Knight Rises podcast.)
Then again, by now a lot of us know how Academy mentality works: Peter Jackson had to wait three years after the release of the first Lord of the Rings film to snag his Oscars, which were piled on in honor of the concluding chapter, Return of the King - which some people will say is arguably (arguably) the weakest film in that trilogy. Could Nolan be due for a simliar late reward after being snubbed (air quotes)for both The Dark Knight and Inception?
Considering the changes to the Best Picture category (which has seen an increase of potential nominees in the last few years), there is plenty of room for Dark Knight Rises to fit into the race; however, the competition is far from a lock. This is year in which awards-magnet director Steven Spielberg unites with awards-magnet leading man Daniel Day-Lewis in the awards-magnet genre of historical drama (Lincoln - read our review), so all this Batman Oscars talk could turn out to be a moot point. Given the level of critical acclaim and public interest, Honest Abe sweeping the Oscars would surprise no one.
[poll id="444"]
The Dark Knight Rises will hit DVD/Blu-ray on December 4, 2012 - just in time for the holidays!
Source: Daily Variety (via /Film)


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Home to the legendary Survivor series amongst others, while away some time playing some of UKMIX's great music games.
An archive for all Survivors and games.
Taylor Swift - Lover -...
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Welcome to Continental Transmission
Continental Transmission is Western New York's largest transmission repair shop and dealer - expertly handling transmission repair work for both domestic and foreign vehicles. Celebrating 45 years of service, Continental Transmission has been locally owned and operated since 1974.
We understand repairing your car's transmission can be a costly undertaking, but we take pride in doing the job right - never using sub-par or cheap transmission materials or cutting corners. Our #1 focus is to provide customers with quality work at a fair price. We won't try to sell you unnecessary repairs - only what you need, when you need it.
We welcome all extended warranties, provide free road tests and visual inspections, offer free towing with service* and will assist you with 0% financing** whenever necessary. These are just a few of the ways we try to live by our motto to "Do The Right Thing".
*free towing up to 25 miles with paid service
**financing subject to credit approval
Free TowingContinental Transmission offers Free Towing up to 25 miles with service.
Free Estimate & DiagnosticWe'll diagnose your transmission problem and prepare an estimate at no charge to you.
Financing AvailableIn need of a transmission but don't have the funds? We offer low or no-cost financing with credit approval.


text:
EXCLUSIVE! A Booth & Brennan Romance On 'Bones'? Emily Deschanel & David Boreanaz Say It's 'Not Worth It'!
You've been waiting for this Bones couple to get together for EVER! But unfortunately, BFFs, the show's stars say it's never going to happen!
We hope this is a joke! We've been waiting for a Booth and Brennan romance to happen for AGES on Bones, but the show's stars say risking their onscreen relationship isn't worth the risk! Are they joking?
Read on to hear what Emily Deschanel (Brennan) and David Boreanaz (Booth) – who showed up at the San Diego event July 22 although he is currently being sued for sexually harassing a Bones extra – had to tell us today at Comic Con, BFFs!
HL – So, based on the information that there is a new love interest on the show for Booth, are Booth and Bones going to start dating or do you think when things are all said and done, it's not worth it?
Emily Deschanel – It's just not worth it…
David Boreanz – It's just not worth it… OK Let's just end the show…BYE!
Hart Hanson (EXECUTIVE PRODUCER) – After 9 seasons we'll go, Oh it was never worth it! I think everything happens eventually.
DB – Yeah, it's a journey, you got to look at it, where the two characters are, how they identify with each other. how they help each other out, they have always been there for each other and they take chances and trust one another, they need to find some space sometimes, as they did going into season six. And I think the unique thing about it is they'll be able to connect on a whole different level and a deeper level, even though they maybe somebody involved, they'll just get closer, they always get there. It's a hard question to answer. People say, will they or won't they? I don't know?
HH – I think what people really want to know is when? And we're not saying!
ED – I think we should do a thing were we see from the audience how many people want to see Booth and Bones together, and then will ask who doesn't want them together.
So, how many people want Booth and Bones to get together
ED – How many people don't want to see them get together?
DB – How many people just don't care? (LAUGHTER)
ED – How many people like cheese?
HH – Eventually everyone wants them to get together.
ED – No, I don't know how I see that question.. But in general…
DB – In general, not this season!


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The Texas House on Tuesday debated tough new abortion restrictions prior to taking part in a planned vote on the measure, as national activists on both sides of the issue descended on the Capitol building.
Republican Rep. Jody Laubenberg, of Parker, outlined the bill that would require doctors to have admitting privileges at nearby hospitals, only allow abortions in surgical centers, dictate when abortion pills are taken and ban abortions after 20 weeks. Exceptions to the ban would only be allowed when the women's life was in imminent danger.
Democrats and women's rights activists have protested the bill for weeks. The measure failed during the regular session when it failed to win enough support, then died in the first special session due to a 13-hour filibuster by state Sen. Wendy Davis, a Fort Worth Democrat.
The latest news from around North Texas.
Now Republican leaders including Gov. Rick Perry and Lt. Gov. David Dewhurst are intent on passing it quickly through the Republican-controlled Legislature in a second special session. Democrats can do little but slow the bill down, attract as much attention as possible and lay the groundwork for a federal lawsuit to block it once if becomes law.
Davis' successful filibuster put Texas' bill in the spotlight of the national abortion debate, and prominent figures from both sides have been coming to Austin and staging rallies. On Monday night, former Arkansas Gov. Mike Huckabee spoke to abortion rights opponents. The Planned Parenthood Federation of America announced a statewide bus tour Tuesday morning, called Stand With Texas Women.
"It seems like every time women looked up from doing their laundry of helping children with their homework, the Texas Legislature is right there taking aim at them again," said Cecile Richards, president of Planned Parenthood Federation of America. "Over the past few years, more than 50 women's health centers have been shut down."
Women from both parties who support abortion rights introduced a series of amendments to water down House Bill 2, hanging coat hangers on the front podium to symbolize illegal abortions, which they say will become more common if the law is passed. Rep. Senfronia Thompson, D-Houston, called for an exception to the 20-week ban in cases of rape and incest, but Laubenberg rejected the proposal.
An anti-abortion voting record is critical to winning Republican primaries in Texas. Texas Alliance for Life, a Christian group that maintains a scorecard on lawmakers, sent Tweets opposing each amendment, signaling how lawmakers should vote for a high score.
Supporters of the restrictions insist that they will improve the health care women receive by placing more stringent conditions on abortions. Laubenberg told the House on Tuesday that her bill would ensure that women get high-quality treatment while protecting "babies" after 20 weeks of gestation.
"What we're talking about today truly is about the health and safety of a woman who would undergo an abortion, but also, I want to point out, we are talking about an unborn child," she said.
Federal courts have ruled that states can regulate abortions, but not to the extent to make them impossible to obtain. That hasn't stopped Republican-led legislatures in Texas and several other states from passing laws in recent years that test the legal limits.
Opponents of the Texas restrictions say they would effectively ban abortion in much of the nation's second most-populous state causing the closure of 37 of its 42 abortion clinics.
Houston Rep. Sarah Davis, the only Republican opposed to the law, warned that the bill as written is unconstitutional and she offered an amendment to make it less stringent.
"I believe the bill as drafted will be a de facto ban on abortion," she said. "No one wants to see abortions, it's a terrible way to end a pregnancy, but it is a constitutionally protected right."
They also say the Texas restrictions and those passed by other states conflict with the U.S. Supreme Court's 1976 Roe v. Wade decision, which established that a woman has the right to get an abortion until her fetus could viably survive outside of the womb, which is generally at 22 to 24 weeks of the pregnancy.
It's unclear if the Texas restrictions could survive a court challenge. Federal courts have suspended aspects of the bill passed by other states. On Monday, a federal judge blocked enforcement of a Wisconsin abortion law requiring admitting privileges.
The Texas Medical Association, the Texas Hospital Association and the American College of Obstetrics and Gynecology oppose the bill, calling it unnecessary.
The Texas Department of Public Safety has more than doubled the number of troopers at the Capitol due to the rallies and marathon hearings, said Sen. Kevin Eltife, a Tyler Republican who oversees the Senate Administration Committee. He declined to reveal the exact number of troopers or how much the boost in security cost.
Lawmakers told the DPS they wanted plenty of troopers on the ground no matter the expense, he added.
NBC 5's Omar Villafranca tweets from Austin follow him on Twitter @OmarVillafranca


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GOP avoids gay marriage issue
When Democrats announced that their 2012 platform would include a historic first — gay marriage written in as a plank — the reaction from mainstream Republicans was near silence.
There were no statements blasted out from Mitt Romney's campaign. The same was true for the Republican National Committee. Romney has yet to address the fact.
Story Continued Below
The pushback came largely from social conservatives and evangelicals, who pledged to make same-sex unions an issue going forward and insisted the stand will hurt Democrats.
( PHOTOS: 20 gay rights milestones)
But the comparative quiet from party leaders would have been unimaginable even four years ago, when public opinion hadn't yet shifted so rapidly on a signature social issue. And it marks a dramatic change among some of the top Republican donors and opinion-makers, who are supporting same-sex marriage in state-based gay legislative and legal fights, even as the official GOP platform will remain centered on traditional marriage.
"Most Republican Party leaders seem to have lost the stomach for this fight," said Dan Schnur of the Jesse M. Unruh Institute of Politics at the University of Southern California. "Some of that results (from) the number of large-scale donors who support same-sex marriage, some of it's a result in an increasing number of party leaders who support same-sex marriage, and a lot of it is public opinion polling which shows a shift in the way voters feel about same-sex marriage," he added.
It is, Schnur said, "still an issue that motivates the party base, but it motivates the Democratic base, too."
It was just eight years ago that Republicans, looking to turn out their base, put gay marriage bans on ballots in key states. The measure in Ohio is widely credited with boosting turnout that benefited President George W. Bush's reelection effort.
And it was just three years ago that a Maine law allowing same-sex marriage was repealed by voters.
But in recent years, polling and ballot initiatives have shown the American public coming closer to a rough consensus on the issue.
In a Pew Poll released last week, the Democratic base has moved significantly on the issue since President Barack Obama announced his support of same-sex marriage, with 65 percent now backing it — making it an easy call for the Democratic convention. Among Republicans, Pew showed less movement, with 70 percent opposed to gay marriage. But equally significant was the figure showing 51 percent of independents supporting gay marriage, along with 48 percent of voters overall, compared to 44 percent against.
"I think that they [the right] know that this issue doesn't have the same potency that it had in 2004," said Christopher Barron, co-founder of the gay group GOProud. "The gay marriage issue for the anti-gay marriage right has always been one of those issues of diminishing returns, and it's gotten to the point now where it's often a loser."
"If you're talking about it, you're not talking about what people care about," he added.
When asked about Romney's view on gay marriage, his campaign reiterated in a statement that he believes marriage is between a man and a woman. But Romney has focused his message almost entirely on the economy and has done everything he can to avoid veering off it on the stump, with the exception of issues that he feels are parallel, such as Obama's health care legislation.


text:
While an end-to-end management approach provides a competitive service advantage, it can carry a substantial additional – and often unforeseen – cost and risk. The challenge is that it's difficult to estimate the costs of all downstream variables and potential problems. It is for this reason most software providers work on a Time & Material basis, whether it's for, say, creating a custom application or the migration of a set of applications onto a new enterprise platform (e.g. porting legacy accounting, inventory and reporting systems into a new ERP solution).
The inevitable – and frequently unforeseen – management and consultancy requirements that typically crop up during a project are usually charged at a day rate, which can become a very risky exercise as costs and timescales creep higher.
What this service provider needed to know was whether offering a full life-cycle management service and incorporating all aspects of service delivery management (including these unforeseen professional services requirements) made sense as a viable business model.
Could it be realistically packaged on a fixed price basis while safeguarding the provider against loss? Finding the answers to this question was what lay at the heart of the study, and involved an in-depth research and drill-down analysis.
Read all about it here


text:
From the mind of Chris Roberts, acclaimed creator of Wing Commander and Freelancer, comes STAR CITIZEN. 100% crowd funded, Star Citizen aims to create a living, breathing science fiction universe with unparalleled immersion… and you're invited to follow every step of development.
More than a space combat sim, more than a first person shooter and more than an MMO: Star Citizen is the First Person Universe that will allow for unlimited gameplay.
Push the limit and avoid g-forces during combat, or switch off IFCS and maneuver with six degrees of freedom like a real spacecraft. Manage your shields, energy signature, thrusters, armaments and dozens of other ship systems.
Navigate treacherous jump points, fly through derelict hulls, dodge massive asteroids, slip undetected through nebulae, face off against unidentified aliens and more. Being the first to chart new regions of the galaxy means being the first to deal with the unknown.
Individual spacecraft components have their performance impacted directly by the cargo you choose to carry. Race at top speed to transport documents or max out your thrusters with a load of scrap. Every player's ship will have its own unique configuration, so there will never be a 'standard' encounter.
Live your own deep space adventure. Star Citizen places you in the middle of a living, breathing science fiction universe populated with friends, enemies and the unknown.
You decide how to make your way in the galaxy, whether you're a simple merchant trader, a fearsome pirate or a badass mercenary… and anything in-between.
In Star Citizen, you control your destiny as you inhabit a world more immersive than ever before.
Choose your ship, choose your profession and choose your allies. Whether you're searching for the perfect thruster upgrade for your Hornet or smuggling ancient alien artifacts across the Xi'An border, every choice impacts how Star Citizen's world reacts to you.
Play the character you've always dreamed of being and build YOUR place in the galaxy.
It's your world: reserve your own corner of Star Citizen by backing to support the game during development. You'll start off with your own Hangar and starship, along with everything you need to begin a career that could change the fate of the galaxy. What's more, you can start playing parts of the game today WHILE we're still constructing the universe.
Star Citizen features a fully realized death mechanic, giving exceptional weight to your choices. It's a world where taking an additional risk might mean a windfall of credits… or your lifeless corpse orbiting an asteroid.
Every Star Citizen trailer features 100% in-engine content using actual game assets. Our aim is to show you the game we're building, not to stun you with pre-rendered cutscenes. With the attention to detail we're putting into Star Citizen's world, you're forgiven if the two seem like one and the same.
Star Citizen's ships don't just look good, they fly in accordance with a detailed Newtonian physics engine. The game offers a full rigid body simulation of all spacecraft; if it flies in Star Citizen, we've figured out exactly how and why.
The game features numerous built-in flight models that will let you treat your ship like a traditional space combat game… or break the mold and pull off maneuvers that should only be possible in zero G.
We've worked hard on making sure Star Citizen's flight model stands apart from everything that has come before. Ship performance is calculated dynamically based on dozens of physical variables and the ability of your maneuvering jets to deliver thrust towards a requested vector.
Every single ship customization impacts how your ship flies.
Every one of Star Citizen's spacecraft features a comprehensive fly-by-wire system that allows even novice pilots the ability to get into the action. While IFCS is active, your ship will respond in a natural manner familiar to most flight sim pilots.
You aren't flying an airplane. Switch to any number of alternate flight modes to maneuver like a true spacecraft: reverse thrusters to stop dead in space, strafe in any direction… even disable IFCS altogether for complete 6DoF control over your ship.
Star Citizen doesn't just simulate the spacecraft, it also simulates the person inside it. It's easy to push your machine to the limit… just make sure your pilot can take the maneuvers. Playing fast and loose with the joystick can get you an advantage in combat… but if you push too hard, you're liable to black out, sustain permanent injury or worse.
Don't rocket into the unknown by yourself: Star Citizen features an array of multi-crew ships that teams of players can operate together. Imagine yelling "fighters inbound, on our six." to your turret gunner, as your chief engineer desperately tries to keep your fusion engine together.
From small freighters to luxury star yachts to military warships, there's a larger ship for every role and a role for every player. Whether you're an aspiring pilot, gunner, engineer, medic, navigator or any of a dozen other optional crew positions, you can join with your friends and take on the universe.
Star Citizen goes beyond the traditional 'man the guns or fly the ship' experience. Star Citizen crews can include everything from navigators to doctors to interceptor pilots, all with a unique and fulfilling role to play.
From the start of the project, Star Citizen has been about building a community… and now that community is becoming a universe. We're giving players ownership of the Star Citizen world now so they'll be invested in the game world when the persistent universe launches.
Lots of guns? Check. Plenty of missiles? Check. But you aren't just picking your weapons in Star Citizen… you're building the ship of your dream with individual components. Overclock your engine to run beyond specifications, install new targeting software or even build a stealth spacecraft by reducing your components' electromagnetic emissions.
There will always be a place for the lone wolf in our universe. Crew a larger ship with NPCs, or choose one of Star Citizen's array of single-seat ships. Options range from the jack-of-all-trades Aurora to the dedicated Herald info-runner hacking ship. There are endless experiences for the solo player.


text:
I'd rather manage in it, but I love being at the WS
ARLINGTON — I want to first start off by saying thank you to all my fans for their support during the hectic 2010 season, easily the longest of my professional career. I wanted to get this blog up and running to serve as an easier way to connect with you fans, in English and Spanish. That's the same reason why I started my Facebook and Twitter pages, and don't think that I don't read everything you guys say. (I do so especially when I'm bored, haha.) I look forward to seeing your comments and questions on here and will do my best to answer as many as I can.
14 Comments
We love you here in Chicago Ozzie. Don't let Kenny bait you into any arguments. You're a bigger person than he is.
Next Year, Ozzie! We keep the rotation healthy, bolster the bullpen and get a left handed bat, then crush the twins all year long!
Have a good winter, Ozzie! You've earned it.
Hi Ozzie..do you see Sale as a starter or reliever in 2011?
Also, I'm concerned that Quinton cannot stay healthy for an entire season..any thoughts? Go Sox!
i think your blog is awesome. I hope you keep it going thru spring training. It's very interesting to hear what you have to say without worrying if the newscasters are only going to show us a sound bite.
You're the best Ozzie!! can't wait for 2011
Well, it is a blog and not twitter so there's no shame on using spell check or having someone writing it for him but I'm sure he's the one saying the words.
Ozzie, give them hell.e manager of the White Sox for another 10 years.
Love me my White Sox. It hurt to see the season end so badly. The guys played their hearts out. Do you think Chris Sale has the capacity next season to log in 200+ innings as a successful major league starter. I am excited about the possibility of a Sox starting staff pitching in the homer happy Cell with a lefty and righty (Edwin Jackson) who throw in the high 90's.
Hi Ozzie,
I'm trying to learn to cook some new foods. What are some good, easy Venezuelan recipes I can make?
Who's writing this for Ozzie? This reads nothing like his tweets….meaning, the posts are grammatically correct (no offense meant – I understand another language but putting together a proper sentence that is structured differently than an English sentence is HARD)
Happy Halloween! Loved seeing lots of kids at my school dressed up at Sox players. Looking forward to Spring training. Q: Where would you recommend visiting in Spain if we only have a week?
Ozzie I think twins fans love you more then whitesox fans. If garden hire ever gets fired you would be the first in line in my books. Love the passion you bring keep it up!
Primero, yo quiero decir que mi espanol no es bueno. Soy de San Francisco y tengo diecisiete anos. Soy un grande fanatico de los Chicago White Sox y fui al Houston en 2005 a ver partido quatro. Yo quiero decir que eres un insparacion a mi y yo creo que tu esta el mejor gerente en el MLB.
-Peter L
Hey Ozzie. Que bueno que decidistes crear una blog. Soy una gran fanatica de Los Dodgers asi que esta Serie Mundial es una pesadilla que los Gigantes esten en la serie pero lo estoy mirando. Como tu, desearia que se fuera hasta los siete juegos.
Buena suerte. Me encanta que vos y Bengie tengan una blog. Yo tambien tengo una que empeze en el 2009.
Good luck in 2011!
Ozzie, you are the greatest! I love your passion and enthusiasm! Keep it up!
So what happened in 2010? Why did the team, especially the pitching, collapse in September? If we had played like we played in July and August, we could have crushed either the Giants or the the Rangers (I believe we did crush the Rangers in July).
We need to do something to be more consistent, especially the pitchers. Floyd, Danks and Buehrle have incredible hot streaks, then seem to fall apart. How can we step up to the next level?
Thanks for all you have done Ozzie. You were great as a player, and you are equally great as a manager. I waited my whole life to see the White Sox win the World Series, and I never thought it would happen. But you did it!


text:
Congenital heart disease is a term that describes a number of different conditions caused by abnormal or disordered heart development before birth. Although congenital heart disease, by definition, is present at birth, its effects may not be obvious nor may present for many years.
A congenital heart defect most often occurs as an isolated incidence and is generally not associated with other diseases, there are a few genetic and chromosomal syndromes that can also cause heart defects, including:
- Down syndrome
- Ellis-van Creveld syndrome
- Marfan syndrome
- Noonan syndrome
- Trisomy 13
- Turner's syndrome
Drugs, chemicals, and infections during pregnancy may also cause congenital heart abnormalities. In infants, fetal rubella, maternal alcohol use (fetal alcohol syndrome), and use of retinoic acid (for acne), may also cause congenital heart disease. In addition, if a pregnant woman has congenital heart disease, she should notify her doctor so her fetus may be checked during the pregnancy.
Surgical treatments and catheter based treatments are tailored to correct the specific congenital abnormality. The most common include closing a patent foramen ovale and/or an atrial septal defect (ASD).
Learn more here about the Washington Adult Congenital Heart Center
Call Us Today
To find a heart specialist, call:


text:
My Dearest Liam,
My heart and mind are simply aching. I cannot get through a morning or an evening without longing for you until the pain is too great to bare. I cannot sleep because tomorrow will come sooner and it will start all over again..... yet another day without you. Tears roll down my cheeks so often that I am often surprised when they are not. I have discovered new ways to breathe and to distract myself when I am in a place where I feel as if tears should not be present. I have found that mornings are very hard for me. Even riding in a cab is trying because looking out of the window at the world around me immediately becomes time to reflect on what is not right in my world. Simply breathing takes determination because it no longer feels involuntary like it should. I try and imagine how for the rest of my life I will feel this bottomless void and unimaginable sorrow, and what it might do to me over time. I contemplate what Ella's life will be like without her brother and how your mom and I will come to terms with this loss we have been dealt. I have always believed I was a survivor; stronger emotionally, physically, and mentally than many. Much of this strength came from insulating and or distancing myself from my feelings. You though my sweet loving son broke through all of my defenses and I loved you like I never imagined possible. So much that it scared me and especially so when I realized that I might lose you to something I could not see or fend off. No matter how much I might have tried to protect myself ....your smile, touch, and the sweet hypnotic sound of "Daddy I love you" was far more powerful than anything I had at my disposal. My armor was stripped from me and now I cannot defend myself from the pain and misery that I am left with in your absence. I feel guilty for not being able to make you better. I vowed as all fathers do to protect my child at all costs and I was not able to. I tried so hard and fought with so much hope and it just was not enough. I am not one who accepts failure and will keep getting up, trying again and again; harder each time. But how I get up from this loss and continue to fight I do not know. What am I fighting for when I have already lost what is unimaginable and immeasurable? Do I continue to fight because I have nothing to lose? Do I stop fighting and just live my life quietly? Can I remain as close to pediatric cancer as I am now? Knowing doing so will invite sad memories back and often.
I was so worried my fear would show on my face as your battle went on because you could always tell if something was bothering someone. When I would look at you and you would stare into my eyes and just nod your head up and down without uttering a word...I wondered sometimes if you knew more than you let on. I wondered if you were telling me "I am ok Daddy...everything is ok" because you could sense my fear. Liam, I m sorry the world has not put enough of a priority on saving kids. I am sorry that bureaucracy and profit are what cover up so many issues and that not enough people choose to stand up for what is right. I am sorry your type of cancer had not had enough attention paid to it over the years, and still to this day cannot be treated effectively. I am sorry most humans cannot see what is right and wrong and when they do they often look the other way because it is easier. Most have lost their will to fight back. Liam, I am sorry your hopes and dreams were cut short and all you desired from this world was not to be had. I am sorry we all failed you. I am sorry we never got to use the woodworking bench and tools you got from Santa. I am sorry I had to go to work when you wanted me with you, and I am sorry that I could not wish a snowstorm, rainbow, beach or the sun whenever your heart desired.
I hope you were not scared to leave us and that you felt no pain. Not knowing is something that brings me the greatest heartache and is often when I find it hardest to breathe. I try and cling to the memory of you reaching past me and smiling like you knew where you were going....you were not afraid but I certainly am. I have so many questions I feel must be answered for me to find any ounce of peace and yet I know they never will be. I know I must compartmentalize all that we as a family have endured and find a way to move ahead; but anyone who knows me at all knows how hard it will be for me to do that. I worry that I am not going to be able to let go and to be able to package this up neatly and trick myself into some false sense of happiness. Most people manage to accept the many ills of our world and to tolerate the lies that surround nearly every topic, but we both know I am not one of those people. I feel it would be wrong not to let the reality of my loss drive my actions, feelings, and beliefs. The weight of this world without you is so heavy it often feels like I might not be able to bare it. It is more difficult than ever to deal with or relate to day to day issues when they all pale in comparison to the tragedy of losing a child to cancer. A couple months have gone by since you earned your wings and each day I miss you more. Nothing could have prepared me for the emptiness I feel inside. I try and find some comfort in knowing you are in a better place than I and free of the burden of your broken body. Your sister Ella is amazing and brings mommy and I sunshine each and every day. It's almost as if she knows she is now the glue that needs to hold us all together and you would be so proud of how much love she gives us and how brave, compassionate, and fun she has been. I am not sure how we would get through each day without her light. Watch over her and keep her safe. You are her angel and we tell her so. She misses you so very much and always will. I thank god for choosing us to bring you into this world, and though my heart now aches for having to give you back, I would not trade our time together for anything.
I want you to know I am proud of you Liam and it is amazing to see those you inspired doing so much to fight for other kids, and in your honor. You were the inspiration for something that is becoming quite remarkable. Know that mommy and I and many others who love you are working very very hard to make sure it lives on and grows into something that will stand the test of time. Your light and spirit will one day be responsible for saving the life of a kid just like you. I hope to know just who that kid is and when he grows up I will be sure to tell him your story. Your friends are baking so many cookies and having bake sale after bake sale, and all for you Liam. Your love and spirit are contagious and you have inspired not just me and mommy, but thousands of others. You have given many wonderful people a purpose and they surprise us each day with their noble and selfless acts.
Liam I am not sure what to do this Friday. It is the day I watched you come into this world 7 years ago and a day that has always been filled with such emotion. I know it is going to be a very hard day and not sure how to make sense of the mix of emotions that are already building. I am not sure yet if writing will help me or if it is simply salt in an open wound. I know I have a desire to capture and preserve the memories that I am so afraid of losing, and while they are fresh and vivid in my minds eye. I miss you my sunshine. Happy Birthday Liam. I love you and miss you to the moon and the stars and back again...
"You are my sun"
by Sun Kil Moon
You are my light
Dark cities, you fill the loss
Of the day
You are my love
Radiant and pretty, over seas
You find ways of bringing hope
The lonely hours, gloom of night
Empty mornings
You are a stem, of wild flowers
Rollin' hills, 'round the bay
You are a gap
In the meadow, soaring low
In this way, you are my friend
In the shadows, there to bring
When I need
You are the suites
Of the cellos
There to mend, if I bleed
You are a swing
Sleepy porches, the warm light
On my face
You are a charge, of wild horses
You are the sun
You are my SON
Sleeping over spilling out
Over the mountains
You are my sun
link to song on itunes
Thank you to all who are doing so much to honor Liam this month and helping to bring awareness to the cause in hopes of inspiring others to join in the fight against pediatric cancer.
Your love and support carry us forward and together we can and will make a difference.


text:
Cornell Green back at Cowboys stadium
ARLINGTON, Texas — I told Cornell Green that I watched him play cornerback for the Dallas Cowboys.
"Well, you must be old then," Green said, laughing.
Yes, Cornell. I'm old enough to have seen you play cornerback in the 1960s and safety in the 1970s. It's a shame he hasn't joined his secondary mate Mel Renfro in the Cowboys' Ring of Fame.
In 1981, former Cowboy halfback Dan Reeves became the Broncos' head coach and he brought Green with him to serve as a scout. Green has been a Broncos scout ever since. Living in the Dallas area, Green attended the Broncos' preseason game against the Cowboys here Thursday night at AT&T Stadium.
"I'm a Bronco," said Green, 74. "I've been working for the Broncos for 35 years.


text:
The weather at the Isle of Man is predictably, unpredictable. One minute it's sunshine, and if you're really lucky, stays that way for a few hours—not for me. I saw but maybe two hours total, the rest was fog and rain for the duration of my stay. Now, this shouldn't be a deterrent when considering that you're in town for the famous Isle of Man TT race, an annual racing event geared for motorcyclists and one that always encounters wet weather. If you're thinking, "What the hell is Super Street doing at a motorcycle race?"—well, I was only partially there for the bikes. I was sent more on a mission of faith, to take Subaru's BRZ and go absolutely apeshit on the IOM's public roads. Add in blinding fog, one lane roads meant for two-way traffic, wet line racing on a former WWII air field and trying to play catch-up with one of the UK's most talented rally drivers (who also happens to be a native of the Isle of Man) and, well, that's what you call "seat time" in a BRZ.
If you're further confused as to why Subaru would even bring a few BRZs out to this part of the world, I must point out that it's because of Subaru's partnership with the Isle of Man TT, serving as the Official Car Partner of the race series. It was on the 37.75-mile stretch of (closed) road that the aforementioned driver, David Higgins, a member of Subaru's Rally Team USA, became the first driver since Tony Pond in 1990 to complete the course, albeit in a lightly-prepped, US-spec 2011 STI. Higgins wound up setting a record time for a production car with 19:00.37 and a top speed of 162mph. Weather permitting, Subaru managed to convince the IOM TT officials to let us have one full run at the course, a rare opportunity for anyone to do—however, if a single drop of water hits the ground (ok, more like light drizzle), they cancel all racing activities for the day, including our run session (yes, we were scheduled to drive in between motorcycle heats). Ha, and they're expecting us to keep up? No problem. All we had to do was pray for no rain.
After long transit times and a very restless night, our group headed out early to survey the IOM TT course in it entirety. While it had been quite dry the day before, that morning saw grey and dark skies with a hint of mist drawing downward. Not ideal conditions for driving but not a total loss either. The interesting thing about the IOM TT course is that it uses the island's public roads, so in order to make your way up to the grandstands (or anywhere to be honest)—and also to accommodate locals—the track goes "cold" at various times and people are allowed to drive normally. We completed our initial demo lap around the island and then stopped off at the IOM TT's main grandstand to take a look at how the event's set up, look at competing teams' pit areas and also to see if the rain would let up or worsen—of course, it started to rain. This called for a slight backup plan, so to keep us entertained, we went to our first ride-along session with Higgins, where we came face to face with his newly-prepped BRZ. By this point, we were far from where we began, much higher up in altitude and with it, torrential downpour—and wind, lots of it. That made for a very fun shotgun experience as things like rain and 'limited traction' don't scare Higgins easily—my quick jaunt up and down the countryside took only a few minutes, but it was evident that this guy has earned his keep as a Subaru rally driver. Fast, very controlled, and this was just the beginning.
Although the weather continued to worsen, by no means did that suggest our day was over; the driving went on—we even sped up. We'd switch between standard public streets and when Higgins felt like it, he'd break off on various back roads where keeping the gas pedal down on the ground was a scary necessity. But this is where one starts to experience the greatness of the BRZ's performance; the power from the FA20 is low but more than enough to take advantage of its superior handling. It's evident that Subaru (and their partners over at Toyota) put a lot of love into it. We made a second stop at Jurby Airfield, located on the northern tip of IOM that was used by the Royal Air Force in WWII as a training base that's since been converted into a motorcycle race track. We used Jurby as our playground for the rest of our afternoon. Once again, we were offered a few hot laps with Higgins, to which he unleashed all hell in his BRZ, sliding the car effortlessly through the course's corners and generating blistering speeds down its straights. My turn at attacking the Jurby circuit wasn't as mind-blowing in comparison, but I still had fun taking as many shots as possible to pretend I was getting close. To close the event out, we played follow the leader one last time through highly questionable downhill sprints where the fog was nearly impenetrable. Apparently it takes a massive set of balls to do what we did, and by no means are we encouraging any of you to do this anywhere at any time.
By the time we left the BRZs to rest, the rain had barely managed to stop, the pavement serving a stern reminder that I had unfinished business with the IOM TT course. It owes me a lap, which I fully intend on cashing in on someday.
Hot Stuff Coming Through!
The Isle of Man course is a playground within an existing community, using public roads as its surface. Signs are everywhere reminding you of the possible dangers, yet people still drive/ride very quickly here. Imagine if your neighborhood was set up like this!


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When you consider it, we're not so nice with our furniture. We plop our heavy selves on top of them and place drinks on them without coasters. We push them around, figuratively and literally. This smart furniture, however, pushes back.
Brooklyn designer Adam Lassy added proximity sensors and motorised wheels to his Ikea furniture, allowing it to rearrange itself based on how many people are in the room and what activities they're engaged in. His work gives a whole new definition to "rolly chair."
But as you can see, smart furniture doesn't necessarily mean cooperative furniture. [Adam Lassy via Make]


text: Sarah Evans Sarah Evans interned at the Diamond Fields Advertiser in Kimberley for three years before completing an internship at the Mail & Guardian Centre for Investigative Journalism (amaBhungane). She went on to work as a Mail & Guardian news reporter with areas of interest including crime, law, governance and the nexus between business and politics. Read more from Sarah Evans @SarahPeace6


text:
Influenza A virus subtype H1N1
Influenza A virus subtype H1N1 is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009, and is associated with the 1918 outbreak known as the Spanish flu. It is an orthomyxovirus that contains the glycoproteins haemagglutinin and neuraminidase. For this reason, they are described as H1N1, H1N2 etc. depending on the type of H or N antigens they express with metabolic synergy. Haemagglutinin causes red blood cells to clump together and binds the virus to the infected cell. Neuraminidase is a type of glycoside hydrolase enzyme which helps to move the virus particles through the infected cell and assist in budding from the host cells.[1]
|Influenza A virus subtype H1N1
|Virus classification
|Influenza A virus
|Influenza A virus subtype H1N1
Some strains of H1N1 are endemic in humans and cause a small fraction of all influenza-like illness and a small fraction of all seasonal influenza. H1N1 strains caused a small percentage of all human flu infections in 2004–2005.[2] Other strains of H1N1 are endemic in pigs (swine influenza) and in birds (avian influenza).
In June 2009, the World Health Organization (WHO) declared the new strain of swine-origin H1N1 as a pandemic. This strain is often called swine flu by the public media. This novel virus spread worldwide and had caused about 17,000 deaths by the start of 2010. On August 10, 2010, the World Health Organization declared the H1N1 influenza pandemic over, saying worldwide flu activity had returned to typical seasonal patterns.[3]
- 1 Swine influenza
- 2 Notable incidents
- 3 In pregnancy
- 4 Additional images
- 5 Notes
- 6 External links
Swine influenzaEdit
Swine influenza (swine flu or pig flu) is a respiratory disease that occurs in pigs that is caused by the Influenza A virus. Influenza viruses that are normally found in swine are known as swine influenza viruses (SIVs). The known SIV strains include influenza C and the subtypes of influenza A known as H1N1, H1N2, H3N1, H3N2 and H2N3. Pigs can also become infected with the H4N6 and H9N2 subtypes.[4]
Swine influenza virus is common throughout pig populations worldwide. Transmission of the virus from pigs to humans is not common and does not always lead to human influenza, often resulting only in the production of antibodies in the blood. If transmission does cause human influenza, it is called zoonotic swine flu or a variant virus. People with regular exposure to pigs are at increased risk of swine flu infection. The meat of an infected animal poses no risk of infection when properly cooked.
Pigs experimentally infected with the strain of swine flu that caused the human pandemic of 2009–10 showed clinical signs of flu within four days, and the virus spread to other uninfected pigs housed with the infected ones.[5]
During the mid-20th century, identification of influenza subtypes became possible, allowing accurate diagnosis of transmission to humans. Since then, only 50 such transmissions have been confirmed. These strains of swine flu rarely pass from human to human. Symptoms of zoonotic swine flu in humans are similar to those of influenza and of influenza-like illness in general, namely chills, fever, sore throat, muscle pains, severe headache, coughing, weakness, and general discomfort. The recommended time of isolation is about five days.
Notable incidentsEdit
Spanish fluEdit
The Spanish flu, also known as la grippe, La Gripe Española, or La Pesadilla, was an unusually severe and deadly strain of avian influenza, a viral infectious disease, that killed some 50 to 100 million people worldwide over about a year in 1918 and 1919. It is thought to be one of the deadliest pandemics in human history.
The 1918 flu caused an unusual number of deaths, possibly due to it causing a cytokine storm in the body.[6][7] (The current H5N1 bird flu, also an Influenza A virus, has a similar effect.)[8] The Spanish flu virus infected lung cells, leading to overstimulation of the immune system via release of cytokines into the lung tissue. This leads to extensive leukocyte migration towards the lungs, causing destruction of lung tissue and secretion of liquid into the organ. This makes it difficult for the patient to breathe. In contrast to other pandemics, which mostly kill the old and the very young, the 1918 pandemic killed unusual numbers of young adults, which may have been due to their healthy immune systems mounting a too-strong and damaging response to the infection.[9]
The term "Spanish" flu was coined because Spain was at the time the only European country where the press were printing reports of the outbreak, which had killed thousands in the armies fighting World War I (1914-1918). Other countries suppressed the news in order to protect morale.[10]
Fort Dix outbreakEdit
In 1976, a novel swine influenza A (H1N1) caused severe respiratory illness in 13 soldiers, with one death at Fort Dix, New Jersey. The virus was detected only from January 19 to February 9 and did not spread beyond Fort Dix.[11] Retrospective serologic testing subsequently demonstrated that up to 230 soldiers had been infected with the novel virus, which was an H1N1 strain. The cause of the outbreak is still unknown and no exposure to pigs was identified.[12]
Russian fluEdit
The 1977–1978 Russian flu epidemic was caused by strain Influenza A/USSR/90/77 (H1N1). It infected mostly children and young adults under 23; because a similar strain was prevalent in 1947–57, most adults had substantial immunity. Because of a striking similarity in the viral RNA of both strains – one which is unlikely to appear in nature due to antigenic drift – it was speculated that the later outbreak was due to a laboratory incident in Russia or Northern China, though this was denied by scientists in those countries.[13][14][15] The virus was included in the 1978–1979 influenza vaccine.[16][17][18][19]
- See also 1889–1890 flu pandemic for the earlier Russian flu pandemic caused either by H3N8 or H2N2
2009 A(H1N1) pandemicEdit
In the 2009 flu pandemic, the virus isolated from patients in the United States was found to be made up of genetic elements from four different flu viruses – North American swine influenza, North American avian influenza, human influenza, and swine influenza virus typically found in Asia and Europe – "an unusually mongrelised mix of genetic sequences."[20] This new strain appears to be a result of reassortment of human influenza and swine influenza viruses, in all four different strains of subtype H1N1.
Preliminary genetic characterization found that the hemagglutinin (HA) gene was similar to that of swine flu viruses present in U.S. pigs since 1999, but the neuraminidase (NA) and matrix protein (M) genes resembled versions present in European swine flu isolates. The six genes from American swine flu are themselves mixtures of swine flu, bird flu, and human flu viruses.[21] While viruses with this genetic makeup had not previously been found to be circulating in humans or pigs, there is no formal national surveillance system to determine what viruses are circulating in pigs in the U.S.[22]
In April 2009, an outbreak of influenza-like illness (ILI) occurred in Mexico and then in the United States; the CDC reported seven cases of novel A/H1N1 influenza and promptly shared the genetic sequences on the GISAID database.[23][24] With similar timely sharing of data for Mexican isolates,[25] by April 24 it became clear that the outbreak of ILI in Mexico and the confirmed cases of novel influenza A in the southwest US were related and WHO issued a health advisory on the outbreak of "influenza-like illness in the United States and Mexico".[26] The disease then spread very rapidly, with the number of confirmed cases rising to 2,099 by May 7, despite aggressive measures taken by the Mexican government to curb the spread of the disease.[27] The outbreak had been predicted a year earlier by noticing the increasing number of replikins, a type of peptide, found in the virus.[28]
On June 11, 2009, the WHO declared an H1N1 pandemic, moving the alert level to phase 6, marking the first global pandemic since the 1968 Hong Kong flu.[29] On October 25, 2009, U.S. President Barack Obama officially declared H1N1 a national emergency[30] Despite President Obama's concern, a Fairleigh Dickinson University PublicMind poll found in October 2009 that an overwhelming majority of New Jerseyans (74%) were not very worried or not at all worried about contracting the H1N1 flu virus.[31] However, the President's declaration caused many U.S. employers to take actions to help stem the spread of the swine flu and to accommodate employees and / or workflow which may be impacted by an outbreak.[32]
A study conducted in coordination with the University of Michigan Health Service — scheduled for publication in the December 2009 American Journal of Roentgenology — warned that H1N1 flu can cause pulmonary embolism, surmised as a leading cause of death in this pandemic. The study authors suggest physician evaluation via contrast enhanced CT scans for the presence of pulmonary emboli when caring for patients diagnosed with respiratory complications from a "severe" case of the H1N1 flu.[33] However pulmonary embolism is not the only embolic manifestation of H1N1 infection. H1N1 may induce a number of embolic events such as myocardial infarction, bilateral massive DVT, arterial thrombus of infrarenal aorta, thrombosis of right external Iliac vein and common femoral vein or cerebral gas embolism. The type of embolic events caused by H1N1 infection are summarized in a recently published review by Dimitroulis Ioannis et al.[34]
The March 21, 2010 worldwide update, by the U.N.'s World Health Organization (WHO), states that "213 countries and overseas territories/communities have reported laboratory confirmed cases of pandemic influenza H1N1 2009, including at least 16,931 deaths."[35] As of May 30, 2010[update], worldwide update by World Health Organization(WHO) more than 214 countries and overseas territories or communities have reported laboratory confirmed cases of pandemic influenza H1N1 2009, including over 18,138 deaths.[36] The research team of Andrew Miller MD showed pregnant patients are at increased risk.[37] It has been suggested that pregnant women and certain populations such as native North Americans have a greater likelihood of developing a T helper type 2 response to H1N1 influenza which may be responsible for the systemic inflammatory response syndrome that causes pulmonary edema and death.[38]
On 26 April 2011, an H1N1 pandemic preparedness alert was issued by the World Health Organization for the Americas.[39] In August 2011, according to the U.S. Geological Survey and the CDC, northern sea otters off the coast of Washington state were infected with the same version of the H1N1 flu virus that caused the 2009 pandemic[when?] and "may be a newly identified animal host of influenza viruses".[40] In May 2013, seventeen people died during an H1N1 outbreak in Venezuela, and a further 250 were infected.[41] As of early January 2014, Texas health officials have confirmed at least thirty-three H1N1 deaths and widespread outbreak during the 2013/2014 flu season,[42] while twenty-one more deaths have been reported across the US. Nine people have been reported dead from an outbreak in several Canadian cities,[43] and Mexico reports outbreaks resulting in at least one death.[44] Spanish health authorities have confirmed 35 H1N1 cases in the Aragon region, 18 of whom are in intensive care.[45] On March 17, 2014, three cases were confirmed with a possible fourth awaiting results occurring at the Centre for Addiction and Mental Health in Toronto, Ontario, Canada.[46][better source needed]
2015 India outbreakEdit
Swine flu was reported in India in early 2015. The disease affected more than 31,000 people and claimed over 1,900 lives.[47][better source needed]
2017 Maldives outbreakEdit
Maldives reported swine flu in early 2017;[48][better source needed] 501 people were tested for the disease and 185 (37%) of those tested were positive for the disease. Four of those who tested positive from these 185 died due to this disease.[49]
The total number of people who have died due to the disease is unknown. Patient Zero was never identified.[50]
Schools were closed for a week due to the disease, but were ordered by the Ministry of Education to open after the holidays even though the disease was not fully under control.[51]
After widespread rumors about Saudi Arabia going to purchase an entire atoll from Maldives, the Saudi Arabian embassy in Maldives issued a statement dismissing the rumors.[52][53] However, the trip of the Saudi monarch was going forward until it was cancelled later due to the H1N1 outbreak in Maldives.[54]
2017 Myanmar outbreakEdit
Myanmar reported H1N1 in late July 2017. As of 27 July, there were 30 confirmed cases and six people had died.[55] The Ministry of Health and Sports of Myanmar sent an official request to WHO to provide help to control the virus; and also mentioned that the government would be seeking international assistance, including from the UN, China and the United States.[56]
2017–2018 Pakistan outbreakEdit
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Pakistan reported H1N1 cases mostly arising from the city of Multan, with deaths resulting from the epidemic reaching 42.[57] There have also been confirmed cases in cities of Gujranwala and Lahore.
2019 Outbreak in MaltaEdit
An outbreak of swine flu in the European Union member state was reported in mid-January 2019, with the island's main state hospital overcrowded within a week, with more than 30 cases being treated.[58]
2019 Outbreak in MoroccoEdit
In January 2019 an outbreak of H1N1 was recorded in Morocco, with nine confirmed fatalities.[59] As of February 4, 11 deaths have been reported in various regions of Morocco.[citation needed]
2019 Outbreak in IranEdit
In November 2019 an outbreak of H1N1 has been recorded in Iran, with 56 fatalities, most of them as a result of Dexamethasone injection, also 4000 people has been hospitalized.[60]
In pregnancyEdit
Pregnant women who contract the H1N1 infection are at a greater risk of developing complications because of hormonal changes, physical changes and changes to their immune system to accommodate the growing fetus.[61] For this reason the Center for Disease Control and Prevention recommends that those who are pregnant to get vaccinated to prevent the influenza virus. The vaccination should not be taken by people who have had a severe allergic reaction to the influenza vaccination. Additionally those who are moderately to severely ill, with or without a fever should wait until they recover before taking the vaccination.[62]
Pregnant women who become infected with the influenza are advised to contact their doctor immediately. Influenza can be treated using antiviral medication, which are available by prescription. Oseltamivir (trade name Tamiflu) and zanamivir (Relenza) are two neuraminidase inhibitors (antiviral medications) currently recommended. It has been shown that they are most effective when taken within two days of becoming sick.[63]
Since October 1, 2008, the CDC has tested 1,146 seasonal influenza A (H1N1) viruses for resistance against oseltamivir and zanamivir. It was found that 99.6% of the samples were resistant to oseltamivir while none were resistant to zanamivir. In 853 samples of 2009 Influenza A (H1N1) virus only 4% showed resistance to oseltamivir, while none of 376 samples showed resistance to zanamivir.[64] A study conducted in Japan during the 2009 H1N1 pandemic concluded that infants exposed to either oseltamivir or zanamivir had no short term adverse effects.[65] Both amantadine and rimantadine have been found to be teratogenic and embryotoxic (malformations and toxic effects on the embryo) when given at high doses in animal studies.[66]
Additional imagesEdit
|Wikimedia Commons has media related to H1N1 influenza.
|Wikimedia Commons has media related to H1N1 influenza subtype influenza A virus.
- ^ Boon, Lim (23 September 2011). "Influenza A H1N1 2009 (Swine Flu) and Pregnancy". Journal of Obstetrics and Gynaecology. 61 (4): 386–393. doi:10.1007/s13224-011-0055-2. PMC 3295877. PMID 22851818.
- ^ "Influenza Summary Update 20, 2004–2005 Season". FluView: A Weekly Influenza Surveillance Report. Centers for Disease Control and Prevention.
- ^ Roos R (10 August 2010). "WHO says H1N1 pandemic is over". CIDRAP. Center for Infectious Disease Research and Policy, University of Minnesota.
- ^ Dhama, Kuldeep (2012). "Swine Flu is back again". Pakistan Journal of Biological Sciences. 15 (21): 1001–1009. doi:10.3923/pjbs.2012.1001.1009. PMID 24163942.
- ^ "Humans May Give Swine Flu To Pigs In New Twist To Pandemic". Sciencedaily.com. 2009-07-10. Retrieved 2010-10-16.
- ^ Kobasa D, Jones SM, Shinya K, et al. (January 2007). "Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus". Nature. 445 (7125): 319–23. Bibcode:2007Natur.445..319K. doi:10.1038/nature05495. PMID 17230189.
- ^ Kash JC, Tumpey TM, Proll SC, et al. (October 2006). "Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus". Nature. 443 (7111): 578–81. Bibcode:2006Natur.443..578K. doi:10.1038/nature05181. PMC 2615558. PMID 17006449.
- ^ Cheung CY, Poon LL, Lau AS, et al. (December 2002). "Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?". Lancet. 360 (9348): 1831–7. doi:10.1016/S0140-6736(02)11772-7. PMID 12480361.
- ^ Palese P (December 2004). "Influenza: old and new threats". Nat. Med. 10 (12 Suppl): S82–7. doi:10.1038/nm1141. PMID 15577936.
- ^ Barry, John M. (2004). The Great Influenza: The Epic Story of the Greatest Plague in History. Viking Penguin. ISBN 978-0-670-89473-4.
- ^ Gaydos JC, Top FH, Hodder RA, Russell PK (January 2006). "Swine influenza a outbreak, Fort Dix, New Jersey, 1976". Emerging Infect. Dis. 12 (1): 23–8. doi:10.3201/eid1201.050965. PMC 3291397. PMID 16494712.
- ^ "Pandemic H1N1 2009 Influenza". CIDRAP. Center for Infectious Disease Research & Policy, University of Minnesota. Retrieved 2011-07-30.
- ^ "1977 Russian Flu Pandemic". GlobalSecurity.org. Retrieved 22 December 2011.
- ^ "Origin of current influenza H1N1 virus". virology blog. 2 March 2009. Retrieved 22 December 2011.
- ^ "New Strain May Edge Out Seasonal Flu Bugs". NPR. 4 May 2009. Retrieved 22 December 2011.
- ^ "Interactive health timeline box 1977: Russian flu scare". CNN. Archived from the original on March 22, 2007.
- ^ "Invasion from the Steppes". Time magazine. February 20, 1978.
- ^ "Pandemic Influenza: Recent Pandemic Flu Scares". Global Security.
- ^ "Russian flu confirmed in Alaska". State of Alaska Epidemiology Bulletin (9). April 21, 1978.
- ^ "Deadly new flu virus in US and Mexico may go pandemic". New Scientist. 2009-04-26. Retrieved 2009-04-26.
- ^ Susan Watts (2009-04-25). "Experts concerned about potential flu pandemic". BBC.
- ^ Centers for Disease Control and Prevention (CDC) (April 2009). "Swine influenza A (H1N1) infection in two children—Southern California, March–April 2009". MMWR Morb. Mortal. Wkly. Rep. 58 (15): 400–2. PMID 19390508.
- ^ "Viral gene sequences to assist update diagnostics for swine influenza A(H1N1)" (PDF). World Health Organization. April 15, 2009. Retrieved August 31, 2017.
- ^ Butler, Declan (2009-04-27). "Swine flu outbreak sweeps the globe". Nature News. doi:10.1038/news.2009.408.
- ^ "Influenza cases by a new sub-type: Regional Update". Pan American Health Organization (PAHO). Epidemiological Alerts Vol. 6, No. 15. 29 April 2009. Retrieved August 31, 2017.
- ^ "Influenza-like illness in the United States and Mexico". Disease Outbreak News. World Health Organization. 2009-04-24. Retrieved 2010-10-16.
- ^ "Influenza A(H1N1) — update 19". Disease Outbreak News. World Health Organization. 2009-05-07. Retrieved 2010-10-16.
- ^ "Efforts To Quickly Develop Swine Flu Vaccine". Science Daily. June 4, 2009. Retrieved December 28, 2016.
One company, Replikins, actually predicted over a year ago that significant outbreaks of the H1N1 flu virus would occur within 6-12 months.
- ^ "H1N1 Pandemic – It's Official". 2009-06-11. Archived from the original on 2009-06-15.
- ^ "Obama declares swine flu a national emergency". The Daily Herald. 2009. Retrieved 2009-10-26.
- ^ "New Jerseyans Not Worried About H1N1" (PDF). Publicmind.fdu.edu. Retrieved 10 February 2019.
- ^ "The Arrival of H1N1 Influenza: Legal Considerations and Practical Suggestions for Employers". The National Law Review. Davis Wright Tremaine, LLP. 2009-11-02. Retrieved 2011-11-03.
- ^ Mollura DJ, Asnis DS, Crupi RS, et al. (December 2009). "Imaging Findings in a Fatal Case of Pandemic Swine-Origin Influenza A (H1N1)". AJR Am J Roentgenol. 193 (6): 1500–3. doi:10.2214/AJR.09.3365. PMC 2788497. PMID 19933640.
- ^ Dimitroulis I, Katsaras M, Toumbis (October 2010). "H1N1 infection and embolic events. A multifaceted disease". Pneumon. 29 (3): 7–13.
- ^ "Situation updates – Pandemic (H1N1) 2009". World Health Organization. Retrieved 2010-10-16.
- ^ "Pandemic (H1N1) 2009 – update 103". Disease Outbreak News. World Health Organization. 2010-06-04. Retrieved 2010-10-16.
- ^ "H1N1 Pandemic Flu Hits Pregnant Women Hard". Businessweek.com. 2010-05-24. Retrieved 2010-10-16.
- ^ McAlister VC (October 2009). "H1N1-related SIRS?". CMAJ. 181 (9): 616–7. doi:10.1503/cmaj.109-2028. PMC 2764762. PMID 19858268. Archived from the original on 2011-05-11.
- ^ "WHO Issues H1N1 Pandemic Alert". Recombinomics.com. April 26, 2011.
- ^ Rogall, Gail Moede (2014-04-08). "Sea Otters Can Get the Flu, Too". U.S. Department of the Interior, U.S. Geological Survey. Retrieved 11 April 2014.
- ^ "H1N1 flu outbreak kills 17 in Venezuela: media". Reuters. 27 May 2013.
- ^ "North Texas confirmed 20 flu deaths - Xinhua". English.news.cn. Archived from the original on 2014-01-12.
- ^ "9 deaths caused by H1N1 flu in Alberta". Cbc.ca. Retrieved 10 February 2019.
- ^ "Un muerto en Coahuila por influenza AH1N1". Vanguardia.com.mx.
- ^ "Aumentan a 35 los hospitalizados por gripe A en Aragón". Cadenaser.com. 12 January 2014.
- ^ "Three cases of H1N1 reported at CAMH - The Star". Thestar.com. Retrieved 10 February 2019.
- ^ "Swine Flu Toll Inches Towards 1,900; Number of Cases Cross 31,000". NDTV.com. 19 March 2015.
- ^ "Makeshift flu clinics swamped as H1N1 cases rise to 82". Maldives Independent.com.
- ^ "Breaking: Swine flu gai Ithuru meehaku maruve, ithuru bayaku positive vejje". Mihaaru.com.
- ^ "H1N1 death toll rises to three". Maldives Independent.com.
- ^ "Schools to open after flu outbreak". Maldives Independent.com.
- ^ Ankit Panda. "Will Saudi Arabia Purchase an Entire Atoll From the Maldives?". Thediplomat.com.
- ^ "Maldives dismisses claims Saudi Arabia buying atoll". Arabnews.com. 11 March 2017.
- ^ "Saudi king cancels Maldives trip, citing swine flu". Presstv.ir.
- ^ Lone, Wa; Lewis, Simon (27 July 2017). "Myanmar tracks spread of H1N1 as outbreak claims sixth victim". Reuters. Retrieved 16 August 2019.
- ^ Htet Naing Zaw (27 July 2017). "Myanmar Asks WHO to Help Fight H1N1 Virus". The Irrawaddy. Retrieved 16 August 2019.
- ^ "Toll rises to 42 as 3 more succumb to swine flu". The Nation. 24 January 2018. Retrieved 25 January 2018.
- ^ Caruana, Claire; Xuereb, Matthew (18 January 2019). "Swine flu outbreak at Mater Dei hospital, St Vincent de Paul". Times of Malta. Retrieved 16 August 2019.
- ^ "Swine flu outbreak kills 9 in Morocco". Al Arabiya. AFP. 2 February 2019. Retrieved 16 August 2019.
- ^ www.yjc.ir https://www.yjc.ir/fa/news/7155842/%D8%A2%D9%86%D9%81%D9%88%D9%84%D8%A7%D9%86%D8%B2%D8%A7-%D9%88-%D8%B1%D8%A7%D9%87%E2%80%8C%D9%87%D8%A7%DB%8C-%D8%AF%D8%B1%D9%85%D8%A7%D9%86-%D8%A2%D9%86-%D8%B1%D8%A7-%D8%A8%D8%B4%D9%86%D8%A7%D8%B3%DB%8C%D8%AF. Retrieved 2019-12-03. Missing or empty
- ^ Boon, Lim (September 23, 2011). "Influenza A H1N1 2009 (Swine Flu) and Pregnancy". Journal of Obstetrics and Gynaecology of India. 61 (4): 389–393. doi:10.1007/s13224-011-0055-2. PMC 3295877. PMID 22851818.
- ^ "Key Facts about Seasonal Flu Vaccine". Centers for Disease Control and Prevention. 2013. Retrieved 31 January 2014.
- ^ "What You Should Know About Flu Antiviral Drugs". Centers for Disease Control and Prevention. Retrieved 31 January 2014.
- ^ "2008-2009 Influenza Season Week 32 ending August 15, 2009". Centers for Disease Control and Prevention. Retrieved 31 January 2014.
- ^ Saito, S; Minakami, H; Nakai, A; Unno, N; Kubo, T; Yoshimura, Y (Aug 2013). "Outcomes of infants exposed to oseltamivir or zanamivir in utero during pandemic (H1N1) 2009". American Journal of Obstetrics and Gynecology. 209 (2): 130.e1–9. doi:10.1016/j.ajog.2013.04.007. PMID 23583838.
- ^ "Pandemic OBGYN". Sarasota Memorial Health Care System. Archived from the original on 2014-02-03. Retrieved 31 January 2014.
External linksEdit
|Wikispecies has information related to H1N1 virus
|Wikinews has related news: Swine flu cases worldwide top 1,000
- European Commission – Public Health EU Coordination on Pandemic (H1N1) 2009.
- Health-EU Portal EU work to prepare a global response to influenza A(H1N1).
- Influenza Research Database Database of influenza genomic sequences and related information.
- Centers For Disease Control and Prevention H1N1 Flu (Swine Flu).
- Consultant Magazine H1N1 (Swine Flu) Center
- Pandemic Influenza: A Guide to Recent Institute of Medicine Studies and Workshops A collection of research papers and summaries of workshops by the Institute of Medicine on major policy issues related to pandemic influenza and other infectious disease threats.
- H1N1 Flu, 2009: Hearings before the Committee on Homeland Security and Governmental Affairs, United States Senate, of the One Hundred Eleventh Congress, First Session: April 29, 2009, Coordinating the Federal Response; September 21, 2009, Protecting Our Community: Field Hearing in Hartford, CT; October 21, 2009, Monitoring the Nation's Response; November 17, 2009, Getting the Vaccine to Where It is Most Needed.
- Shreeve, J. (29 January 2006). "Why Revive a Deadly Flu Virus?". New York Times. Six-page human-interest story on the recreation of the deadly 1918 H1N1 flu virus
- "1918 flu virus's secrets revealed". BBC News. 28 September 2006. Results from analyzing a recreated strain.
- Noymer, A. (September 2005). "Some information on TB and the 1918 flu". Data from Noymer A, Garenne M (2000). "The 1918 influenza epidemic's effects on sex differentials in mortality in the United States". Popul Dev Rev. 26 (3): 565–81. doi:10.1111/j.1728-4457.2000.00565.x. PMC 2740912. PMID 19530360.
- Oral history by 1918 pandemic survivor
- Ludwig S, Haustein A, Kaleta EF, Scholtissek C (July 1994). "Recent influenza A (H1N1) infections of pigs and turkeys in northern Europe". Virology. 202 (1): 281–6. doi:10.1006/viro.1994.1344. PMID 8009840.
- Centers for Disease Control (CDC) (February 1987). "Influenza A(H1N1) associated with mild illness in a nursing home–Maine". MMWR Morb. Mortal. Wkly. Rep. 36 (4): 57–9. PMID 3100930.
- Lederberg J (February 2001). "H1N1-influenza as Lazarus: Genomic resurrection from the tomb of an unknown". Proc. Natl. Acad. Sci. U.S.A. 98 (5): 2115–6. Bibcode:2001PNAS...98.2115L. doi:10.1073/pnas.051000798. PMC 33382. PMID 11226198.
- H1N1 Registry (ESICM – European Society of Intensive Care Medicine)


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|Advanced Ceramics.
|Three semester hours.
A continuation of ARTS 3324, this course will address the interaction of ceramics, materials, and conceptualization. In-class critiques, out-of-class assignments, and independent self-motivated projects are the most important components of this course. May be repeated once for credit. Prerequisite: ARTS 3324. Course fee: $65.
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Can Blockbuster compete with the new Netflix Player? Their first attempt at a box of their own (seen here) looks like it might fall a little short when it comes to streaming movies and TV shows on demand. But it absolutely dominates the competition in the areas of fast food pizza delivery. Different strokes, I guess. [Silicon Alley Insider]
Blockbuster's Box Is Hot Competition for Netflix


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Upcoming RTF Meeting Dates
2016: April 19, May 17, June 21, July 19, August 16, September 20, October 18, November 9, December 6
2016: April 19, May 17, June 21, July 19, August 16, September 20, October 18, November 9, December 6
Regional energy efficiency accomplishments surpassed the Sixth Plan's five year target set by the Council. See results for 2014.
December 2015: At its December meeting, the RTF adopted updates to the consolidated volume series of its Guidelines for estimating Savings, Costs, Non-Energy Benefits and Lifetime. This update to the Roadmap and Savings volumes incorporated significant changes to language and content from the previous operative version of the Guidelines. These Guidelines describe how the RTF will judge whether the quality of the data and analytical methods are sufficient to produce reliable savings estimates. As of December 2015, these are the operative guidelines the RTF will use to judge the quality and reliability of its savings estimates, costs, benefits, and life for measures and protocols.
As part of its 2012 work plan, the RTF enlisted the services of a competitively bid contractor (The Cadmus Group) to assemble the various written and digital elements of the End Use Load and Consumer Assessment Program (ELCAP) and convert the data into a modern searchable database that can be used by regional utilities and the RTF to evaluate 8,760 end use load shapes. As of March 2013, this project has been completed and the final database and associated reports have been made accessible to the public, and can be accessed at this database location online. A username and password are required for security purposes to access the content, however the registration is free. More information can be found on the RTF's ELCAP page.
Use this form to submit required information and files regarding proposed new energy efficiency measures, or to propose modifications to existing RTF-approved measures or specifications.