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Serious morbidity may be linked to sleep disordered breathing (SDB) among children with sickle cell disease (SCD). We investigated the stability of polysomnography (PSG) results among children not having acute complications of SCD.
Two PSGs were performed on a subsample of 63 children 4 to 18 years of age from the Sleep and Asthma Cohort Study. All had Hb SS or HbSβ0 disease. Two PSGs were compared for 45 subjects. Excluded from comparison were 18 children who had begun transfusions or hydroxyurea, had an adenotonsillectomy between the PSGs, or had a pain crisis or the acute chest syndrome within 3 months of the second PSG. Sleep disordered breathing was identified using 2 thresholds for the apnea hypopnea index (AHI): ≥ 2 or ≥ 5 respiratory events per hour.
Ages were 12.3 yrs ± 4.0, BMI, 18.2 ± 3.2. Interval between PSGs was 581 ± 119 days (19.1 ± 3.9 months). Ten of 45 changed from ≥ 2 events per hour to < 2; 3 of 45 from < 2 to ≥ 2; 7 of 45 had ≥ 2 on both nights. Six of 45 changed from ≥ 5 to < 5, 2 of 45 from < 5 to ≥ 5, and 1 had ≥ 5 on both nights (McNemar χ2, p = 0.09, and p = 0.29).
In the absence of acute SCD complications, overnight PSG usually remains stable or improves over a 12- to 30-month period. Only 6.7% subjects, or fewer, had AHI on a subsequent PSG that would re-classify the child as having SDB not identified in the earlier PSG.
Mullin JE; Cooper BP; Kirkham FJ; Rosen CL; Strunk RC; DeBaun MR; Redline S; Kemp JS. Stability of polysomnography for one year and longer in children with sickle cell disease. J Clin Sleep Med 2012;8(5):535-539.
Obstructive sleep apnea (OSA) is more prevalent in children with sickle cell disease than in children without SCD.1,2 SDB has been linked to serious SCD-associated morbidity, including vaso-occlusive crises, pulmonary hypertension, and strokes.3–10 There are several possible causes for the high prevalence of OSA and other types of sleep disordered breathing among children with SCD—stroke, adenotonsillar hypertrophy, airway narrowing due to bone marrow hyperplasia,6 and the increased rate of OSA among African American children in general.11
Among children with SCD, symptoms of sleep disordered breathing may be particularly unreliable—daytime sleepiness or behavioral problems may be due to sleep disruption by pain, pain treatment, or stroke. In addition, preliminary results suggest that more than 20% of SCD patients with sleep disordered breathing do not have habitual snoring.12
PSG is considered the "gold standard" test for evaluating SDB. However, it can be burdensome and its clinical value over a symptom-based classification for children with SCD has been debatable, because of a lack of data on the stability and interpretability of the findings. We investigated whether classification of SDB status changes 1 year or more after an initial PSG in a group of SCD patients who were clinically stable at both the first and second study. To our knowledge, no studies have compared the stability of PSG results over long intervals in children, although short-term variability, or reproducibility, has been addressed.
Current Knowledge/Study Rationale: Particularly serious morbidity is associated with sleep-disordered breathing among patients with sickle cell disease. We investigated whether polysomnography results would change in otherwise stable patients.
Study Impact: Over an 18 month interval, in the absence of worsening of symptoms due to sleep-disordered breathing or sickle cell disease, polysomnography results were stable among patients 4 to 18 years old.
We examined PSG from participants in the prospective, multicenter Sleep and Asthma Cohort (SAC) Study. In this report we evaluated the stability of the respiratory PSG parameters measured after a 12- to 30-month interval. Specifically, among children with SCD who were not selected for any respiratory signs or complaints, we tested the hypothesis that there would be no significant difference in selected respiratory parameters between two sleep studies, done one year or more apart.
Institutional review board approval was obtained at Washington University in St. Louis, Missouri, and Case Medical Center, Cleveland, Ohio.
Participants were excluded from this study if they met any of the following criteria: chronic blood transfusion at time of enrollment, comorbidities such as Pierre-Robin sequence, craniosynostosis, neuromuscular disease, serious preexisting lung disease, or use of continuous positive airway pressure therapy. Patients were not excluded if they had adenotonsillar hypertrophy or prior adenoid or tonsil surgery. A PSG was performed upon enrollment for all patients, provided they were free of pain or symptoms of a respiratory infection. A second PSG was performed later on a convenience sample of 63 patients willing to undergo a second study enrolled at 2 of the 3 SAC sites (St. Louis and Cleveland), when they were free of pain or symptoms of a respiratory infection.
Participants were ≥ 4 and ≤ 18 years old with sickle cell disease: Hemoglobin SS or Hemoglobin HbSβ0 Thalassemia (Hb SS or HbSβ0). Participants who were prescribed hydroxyurea, or had an adenoidectomy, tonsillectomy, or adenotonsillectomy between studies underwent the second PSG but were excluded from this analysis. Any participant requiring supplemental oxygen during a PSG, as determined by clinician's judgment, was excluded from the analysis. Medical records were reviewed to determine which participants were hospitalized for vaso-occlusive pain events or acute chest syndrome within 3 months of a PSG, which participants were hospitalized for respiratory symptoms within 2 weeks of a PSG, and which participants were started on chronic blood transfusion between PSGs. These participants were also excluded from the analysis. None were excluded because of worsening symptoms of OSA between PSGs—snoring, behavioral disturbances, daytime sleepiness, etc. Analgesic drugs were routinely prescribed for as needed use. Frequencies of narcotic use or prescription refills were not analyzed.
Each patient underwent 2 nocturnal PSGs in the sleep laboratories at St. Louis Children's Hospital/Washington University in St. Louis or the clinical research unit at University Hospital–Case Medical Center, Cleveland, Ohio. The PSGs were performed using a standardized protocol and centrally scored at a reading center by research polysomnologists who were blinded to any clinical data, per the SAC protocol as described in detail elsewhere.13 Inter- and intra-scorer reliability were monitored across the study and demonstrated to be excellent for all PSG parameters. Any clinical management decisions made based on the initial study were according to the standards of care at each site.
Obstructive apneas were identified when there was absent nasal-oral airflow by thermistor with continued respiratory effort lasting ≥ 5 sec and 2 missed breaths, regardless of associated desaturation. Hypopneas were scored when there was a 50% reduction in airflow by nasal pressure or 50% reduction in volume by the sum signal from thoracic and abdominal inductance plethysmography and ≥ 3% desaturation continuing for ≥ 5 sec and 2 missed breaths. The obstructive apnea hypopnea index with 3% desaturation (AHI) was defined as the number of obstructive apneas with or without desaturations plus hypopnea events associated with 3% desaturation per hour of sleep.
The prevalence of SDB was assessed using 2 different frequency thresholds of the AHI: ≥ 2 events/h, and ≥ 5 events/h. These thresholds were chosen to approximate conservative thresholds for SDB proposed for children younger than or older than 12 years of age.
Continuous measures of hemoglobin oxygen saturation levels (SpO2 %) were further described for each subject in terms of percent total sleep time levels of oxyhemoglobin saturation of < 95% and < 90%.
Other PSG indices analyzed included total sleep time (TST), percent of TST in REM sleep, percent of TST in the supine position, AHI, and average SpO2% during sleep. Study 1 and Study 2 group-mean differences were compared using unpaired t tests or the Mann-Whitney rank-sum test. The within-subject differences of key variables were compared between nights using paired t tests for normally distributed variables and Wilcoxon signed-rank test for variables that were not distributed normally. Difference values were calculated subtracting Study 1 values from Study 2. All point estimates are presented with 95% confidence intervals unless otherwise indicated.
Further analysis was conducted for the primary metric of AHI. Participants were classified as having SDB using both thresholds (≥ 2 and ≥ 5 events/h) and were classified into 4 groups based on congruency of classification from Study 1 to Study 2: no SDB on both nights, SDB on study 1 only, SDB on study 2 only, and SDB on both nights. Analysis of variance (ANOVA) was conducted on all 4 groups to compare the groups on the basis of age at date of first study, number of days between studies, BMI, time spent in REM sleep, time spent supine, and difference in time spent in REM sleep and in time spent supine. Chi-square analyses were used to compare all 4 groups on the basis of site and gender, using Fisher exact test when appropriate. McNemar test for changes was used to quantify the significance of changes in category (SDB vs. no SDB) from night 1 to night 2, using both ≥ 2 and ≥ 5 event thresholds.
Sixty-three children had 2 PSGs performed an average of 581 [544.7, 616.4] days apart (range: 322-987 days or 10.6 to 32.4 months). Forty-five participants met the inclusion criteria for analysis of both PSGs in this study. Eighteen were excluded because they had begun transfusions (8), hydroxyurea (4), or nighttime supplemental oxygen (1), had an adenotonsillectomy between PSGs (1), or had a pain crisis or acute chest syndrome (4) within 3 months before the second PSG. Five participants were taking hydroxyurea at the time of both PSGs, and were included in the final analysis. Mean age at time of first study was 12.3 [11.1, 13.5] years (range: 4.6-18.7), and 49% were male. Mean BMI on night of study 1 was 18.2 [17.3, 19.2] kg/m2 (range: 14.1-27.7) and 19.1 [18.2, 20.1] (14.7-27.8) on night 2. The change in BMI was not significant, (0.9 [-0.4, 1.3])
(Table 1) Mean difference of AHI between study 2 and study 1 was 1.45 [-0.3, 3.2] and mean difference of average SpO2 between study 2 and study 1 was −0.4 [-1.3, 0.5]. Mean difference of total sleep time between night 2 and 1 was 45.4 [22.4, 68.4] minutes. Mean difference of time in REM sleep and time in the supine position (as a percent of total sleep time) between night 2 and 1 was, respectively, 1.4 [-1.0, 3.7] and 3.0 [-5.1, 11.2]. Except for total sleep time, there were no significant group mean differences between first and second PSG.
Group mean results for sleep and respiratory parameters for PSG nights 1 and 2
(more ...)
The relationship between difference in AHI (night 2 – night 1) and mean AHI (for night 1 plus night 2) for each subject is depicted in Figure 1. One participant with a mean AHI of 7 had 7 more events on night 2 than on night 1. All other participants with large differences had fewer events on night 2 (Figure 1).
One subject had an AHI of 35 on the first PSG, but only 1 event/h on the second. His results are not shown in the plot.
Relationship between mean AHI index for both PSGs and difference in AHI (Study 2 – Study 1) is depicted in the Bland-Altman PlotOne subject had an AHI of 35 on the first PSG, but only 1 event/h on the second. His results are not shown in the plot.
(Table 2) Using AHI with a threshold of 2 events/h, 28.8% (13/45) of the participants changed categories between the 2 studies. A total of 22.2% (10/45) went from ≥ 2 events/h on study night 1 to < 2 events/h on study night 2, and 6.7% (3/45) went from < 2 events/h on study 1 to ≥ 2 events/h on study 2; 15.6% (7/45) had ≥ 2 events/hour on both nights. There was no difference between any of the 4 of these groups (neg-neg, neg-pos, pos-neg, pos-pos) with respect to age, gender, BMI, site, or days between PSG.
AHI threshold of 2 events/hour
(Table 3) Using AHI with a threshold of 5 events/h, 17.8% (8/45) of the participants changed categories between the 2 studies: 13.3% (6/45) went from ≥ 5 events/h on night of study 1 to < 5 events/h on night of study 2, and 4.4% (2/45) went from < 5 events/h on night of study 1 to ≥ 5 events/h on study 2. Only 1/45 (2.2%) had ≥ 5 events/h on both nights. Again, there was no difference between any of the 4 of these groups (neg-neg, neg-pos, pos-neg, pos-pos) with respect to age, gender, BMI, site, or days between PSG.
AHI threshold of 5 events/hour
Changes in classification from night 1 to night 2, for both thresholds, were not significant (McNemar test for changes, McNemar χ2, 3.77 and 2.00, p = 0.09, and p = 0.29, respectively.)
For all subjects, regardless of SDB classification, the average total sleep time with SpO2% < 90% was 8.9% on study night 1 and 4.7% on study night 2; the average sleep time with SpO2% < 95% was 47.3% on study night 1 and 50.0% on study night 2. Individuals did not differ significantly on paired t-tests in percent of total sleep time for oxyhemoglobin saturations < 90% on study night 1 vs. study night 2 (p = 0.3560) or in percent of total sleep time < 95% (p = 0.5319).
Among the 18 subjects who had 2 PSGs but whose results were excluded from the group comparisons, 6 of 18 (33%) had AHI ≥ 2 on study night 1, and 2 of 18 (11%) had AHI ≥ 5. On study night 2, 1 of 18 (6%) had AHI ≥ 2 and none had AHI ≥ 5. Though not explored in detail, this reduction in SDB severity on the second exam is consistent with the more aggressive treatment for SCD these children received.
Because of severe morbidity associated with SDB, an argument could be made to do routine second PSGs as screening tests on children with SCD, even in the absence of progression of symptoms of SDB or abnormalities on the first PSG. Our study showed that among children studied when free of acute illness and not receiving specific treatment for SDB or more aggressive SCD therapy, classification of SDB changed little over an average of 1.5 years. Specifically, using either of two alternative definitions of SDB, most children who were not classified with SDB on the first PSG also were free of SDB later. In contrast, despite an insignificant increase in BMI and without surgical intervention, when the PSG was abnormal on night of study 1, 59% to 86% subsequently had results below the threshold on night of study 2 (< 2 or < 5 events/h, 10 of 17, or 6 of 7, respectively).
The question of which children with SCD to study with PSG, and the frequency of study, is unsettled. In any child with a chronic health condition, changes in overall health, medication use, lung function, nasal congestion, and body weight and other factors all may influence the measured severity of SDB at any given point in time. Furthermore, interpreting PSG in children with SCD can be challenging due to underlying abnormalities in lung function and in oxyhemoglobin saturation, which can obscure the identification of hypopneas among subjects whose hemoglobin has less affinity for oxygen than Hgb A. The results of the current study suggest that a PSG performed when children with SCD were free of acute illness provided an estimate of SDB severity that changes little over 1.5 years. In particular, very few children whose first PSG results were below recognized thresholds for SDB developed new SDB over this period of time. On the other hand, some children with AHI above SDB threshold values were measured to have lower AHIs at a later point. This may be due to a reduction in SDB severity with growth in children (reflecting a relative increase in airway size over tonsillar mass) or could reflect a "regression to the mean." However, even with the latter reclassification, the overall mean change in AHI as well as other PSG parameters were modest, suggesting that for research purposes, a single PSG performed under the appropriate conditions may provide reliable estimates of SDB in children not undergoing interventions that could alter SDB severity.
How less inconvenient or labor-intensive proxies for full PSG might be used in children with SCD deserves attention. However, as noted above, particular caution must be taken when applying methods to assess hypopnea primarily based on SpO2% in patients whose hemoglobin may have unpredictable affinity for oxygen.
Other caveats seem important to the prudent use of our findings. Although less frequently than in children without SCD, habitual snoring, labored breathing, and apnea are associated with SDB among children with SCD,12 and thus a worsening in these symptoms should prompt consideration to repeat the PSG. Even though our findings showed little progression of disease within subjects who did not undergo adenotonsillectomy, these findings should not alter current approaches that demand that progression of symptoms of SDB warrants reevaluation of SDB.
There are several other limitations. First the subjects were a convenience sample from the Sleep and Asthma Cohort. Second, we excluded from analysis patients receiving chronic transfusion therapy and those begun on hydroxyurea between the PSG. Our results are thus most pertinent to patients with less severe SCD and to those who may be using hydroxyurea but not recently begun on this agent. Finally, we did not compare symptoms of SDB before Study 1 to the appearance or progression of symptoms before Study 2. However, of 18 children excluded from comparison, only 1 was excluded because of an adenotonsillectomy between PSGs. Furthermore, only 4.4% to 6.7% of those with a normal PSG on Study 1 surpassed either threshold for SDB on Study 2. This suggests that even if more subjects were snoring or sleepy or had behavioral disturbances that a new classification as SDB would be unlikely.
Most studies on the reproducibility of PSG results in diagnosing OSA have focused on short-term variability. Studies in healthy adults have shown some modest night-to-night variability when the PSGs were performed at intervals < 28 days.14 Reproducibility of PSG results in children has been assessed in a small number of studies.15–17 In one study of children who snored, subjects had PSGs performed 7 to 28 days apart. The classification of OSA or primary snoring remained the same for all 30 participants.16
We did not examine the short-term variability, or reproducibility, of PSG in children with SCD. Rather, we have shown the longer-term stability of PSG in children with SCD who were free of vaso-occlusive crises or the acute chest syndrome for 3 months. In the absence of progression of pulmonary hypertension or new stroke, among children with SCD who are otherwise clinically stable, our results indicate that a second PSG 1 to 3 years after one that is normal is unlikely to show worsening sleep disordered breathing.
This was not an industry supported study. Dr. Redline has received equipment and a grant from ResMed Inc. for use in research. She also received equipment for use in research from Philips Respironics. The other authors have indicated no financial conflicts of interest.
Support for this study provided by the National Heart, Lung, Blood Institute, HL079937.
Sidman JD, Fry TL, authors. Exacerbation of sickle cell disease by obstructive sleep apnea. Arch Otolaryngol Head Neck Surg. 1998;114:916–7
Kaleyias J, Mostofi N, Grant M, et al., authors. Severity of obstructive sleep apnea in children with sickle cell disease. J Pediatr Hematol Oncol. 2008;30:659–65. [PubMed]
Maddern BR, Reed HT, Ohene-Frempong K, et al., authors. Obstructive sleep apnea syndrome in sickle cell disease. Ann Otol Rhinol Laryngol. 1989;98:174–8. [PubMed]
Robertson PL, Aldrich MS, Hanash SM, et al., authors. Stroke associated with obstructive sleep apnea in a child with sickle cell anemia. Ann Neurol. 1988;23:614–6. [PubMed]
Wittig RM, Roth T, Keenum AJ, et al., authors. Snoring, daytime sleepiness, and sickle cell anemia. Am J Dis Child. 1988;142:589
Samuels MP, Stebbens VA, Davies SC, et al., authors. Sleep related upper airway obstruction and hypoxaemia in sickle cell disease. Arch Dis Child. 1992;67:925–9. [PubMed Central][PubMed]
Davies SC, Stebbens VA, Samuels MP, et al., authors. Upper airways obstruction and cerebrovascular accident in children with sickle cell anaemia. Lancet. 1989;2:283–4. [PubMed]
Hargrave DR, Wade A, Evans JP, et al., authors. Nocturnal oxygen saturation and painful sickle cell crises in children. Blood. 2003;101:846–8. [PubMed]
Kirkham FJ, Hewes DK, Prengler M, et al., authors. Nocturnal hypoxaemia and central-nervous-system events in sickle-cell Disease. Lancet. 2001;357:1656–9. [PubMed]
Needleman JP, Franco ME, Varlotta L, et al., authors. Mechanisms of nocturnal oxyhemoglobin desaturation in children and adolescents with sickle cell disease. Pediatr Pulmonol. 1999;28:418–22. [PubMed]
Rosen CL, Larkin EK, Kirchner L, et al., authors. Prevalence and risk factors for sleep-disordered breathing in 8- to 11-year-old children: association with race and prematurity. J Pediatr. 2003;142:383[PubMed]
Rosen CL, Seicean S, Redline S, et al., authors. High prevalence of obstructive sleep apnea in children with sickle cell anemia. Sleep. 2009;32:Abstract 0198.
Johnson MC, Kirkham FJ, Redline S, et al., authors. Left ventricular hypertrophy and diastolic dysfunction in children with sickle cell disease are related to asleep and waking oxygen desaturation. Blood. 2010;116:16–21. [PubMed Central][PubMed]
Lord S, Sawyer B, O'Connell D, et al., authors. Night-to-night variability of disturbed breathing during sleep in an elderly community sample. Sleep. 1991;14:252–8. [PubMed]
Standards and indications for cardiopulmonary sleep studies in children. American Thoracic Society. Am J Respir Crit Care Med. 1996;153:866–78. [PubMed]
Katz ES, Greene MG, Carson KA, et al., authors. Night-to-night variability of polysomnography in children with suspected obstructive sleep apnea. J Pediatr. 2002;140:589–94. [PubMed]
Verhulst SL, Schrauwen N, DeBacker WA, Desager KN, authors. First night effect for polysomnographic data in children and adolescents with suspected sleep-disordered breathing. Arch Dis Child. 2006;91:233–7. [PubMed Central][PubMed]


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subset: commoncrawl


text:
Tuesday, February 24, 2009
Is it time for Wells and Rios to trade places in the field?
We think we may have heard that song and hobbling dance from Wells before. (How sad is it that we can vividly picture the facial expressions that Wells made when he pulled up?)
When and if Vernon Wells is healthy, he's still the Jays best offensive player by a fair margin. Last year, he produced at a 30 homer and 100 RsBI pace when he was in the lineup, although he spent the better part of two months on the shelf with a variety of ailments.
In Wells' time in the infirmary, Alex Rios acquitted himself very well as the Jays everyday centerfielder, showing the range, instincts, arm and speed necessary to play the position. We don't know nuthin' 'bout no defensive metrics in baseball - it all just looks like a jumble of numbers and acronyms to us, but from what we hear, Rios' performance in center was quantifiably better than Vernon's, in spite of the latter's Gold Glove bona fides.
So our question (as the title of this post vaguely suggests) is: Isn't it about time that Vernon and Lexi allemand left and allemand right and dos-si-do and trade spots in the outfield?
Obviously, playing center is a point of pride for a player, and Vernon would be unlikely to just cede the position without some amount of consternation. And if you recall, Wells pretty much had to pry the spot out of José Cruz Jr.'s talons when he first got to the major league level.
At the same time, the move to the right corner of the outfield would save Wells' gimpy legs a certain amount of strain and pounding over the run of the year, which may help him stay healthy and fresh, thus improving his offensive output.
We'd be surprised to see Cito upset the applecart to make such a move. Then again, looking into the future of the franchise, we don't see how Vernon can keep his spot up the middle for the duration of his contract unless he demonstrates that he can keep his legs in proper working order.
23 comments:
- D. Ling said...
Vernon Wells is the worst contract in baseball. Sure his so-called 30HR-100RBI pace was present last year although the last season surge in production when the Jays were way out of the playoff picture exposed VW for being un-clutch.
I would argue all day for Rios being the Jays best offensive player. Hits for power and can steal bases.
In a sad statement, it would probably be safest if VW was the DH and they let the Great White Hope play in RF with Lind in left and Rios in CF.
- February 24, 2009 at 10:56 AM
- Tao of Stieb said...
Clutch schmutch.
- February 24, 2009 at 10:59 AM
- Joanna said...
yeah, clutch schmutch.
the other thing is that Rios is an oblivious gazelle. I can't remember Wells making a bad play due to a brain malfunction.
- February 24, 2009 at 11:31 AM
I heard he was running to get his cheque when it happened.
- February 24, 2009 at 11:38 AM
- Lloyd the Barber said...
Clutch smutch, especially when Alex Rios is much much worse in high leverage situations.
I like my idea about moving Vernon to left, where he could provide excellent defense ala Johnny Damon. The GBPWH could play right cause he's got a cannon.
- February 24, 2009 at 11:43 AM
Vernon Wells is stealing money form the Rogers. It's so sad what he's doing. Some idiot on Drunk Jays Fans claimed that Wells will opt out!!WTF! NO one who never plays will opt out when they are guaranteed 23 mill a year and is always injured. Rios might as well play center becasue Wells will be mostly a DH from the looks of things.....
- February 24, 2009 at 11:53 AM
Vman just needs a few weeks taking it easy and he will come back at 110%. I suggest he rest easy in the DR...since it is so close to FL and all.
- February 24, 2009 at 11:56 AM
- Ian H. said...
I'm all for it, Tao. Rios has the speed to play CF, and the cannon-like arm to quickly get the ball back into the infield.
- February 24, 2009 at 12:30 PM
- Tao of Stieb said...
@Hum and Chuck
Rios is definitely a "blissfully oblivious gazelle" sometimes.
We'd like to work that moniker into our posts a little more often, although we'd really like it if Rios doesn't give us reason to use it.
- February 24, 2009 at 12:45 PM
- dave said...
B-b-b-ut he won a couple of Gold Gloves!!!
- February 24, 2009 at 2:53 PM
- Colin said...
To start the year I'd leave Wells at CF but have him take a turn at DH every few days. I do think Wells has earned the chance to go into the season as the regular CF and then if they feel his defense is costing the team they could re-evaluate.
I also think that while Wells is the team's best offensive player today, by the end of the season I would not be surprised if it was generally accepted that Rios had supplanted him, he has all the potential to be a superstar if he could just put it together.
- February 24, 2009 at 2:59 PM
- The Ack said...
With Wells set to start the season at DH (barring setbacks....), the question becomes, what's the bench makeup to open? Is this the nail in the coffin for Bautista? Come on, Cito's not seriously entertaining him in the OF, is he?
And wouldn't we all rather see Inglett making the club as Rolen's primary backup?
- February 24, 2009 at 3:28 PM
- dave said...
Ack, Bastian talked to Cito today and Cito really wants Bautista in the lineup come opening day so he's going to play him at 3rd, 1st, CF and SHOTSTOP in these exhibition games.
Like I get that he wants to give him at-bats but come on....
- February 24, 2009 at 4:32 PM
- The Ack said...
I saw that after posting my comment, and on that - I have no comment.....wait, yes I do:
Jose Bautista in Center and at Short? WHAT? I feel bad for whoever's on the hill that day (and it won't be Doc, that's a guarantee....)
- February 24, 2009 at 4:47 PM
- Colin said...
To be fair I can see them wanting to get Bautista out in CF in spring training if they're worried Wells won't be ready and they don't have a natural replacement to Rios. Personally I'd rather see Inglett, but I have no idea how to evaluate baseball talent, and Inglett might be starting in the minors anyways.
- February 24, 2009 at 7:23 PM
Free Joe Inglett!
- February 24, 2009 at 8:32 PM
If Inglett learned how to play SS that would resolve one issue
- February 24, 2009 at 8:35 PM
I really don't want to have the Jays SS "learning" in the Majors. That would be what A ball is for.
The Jays have some "interesting" players and I really hope Cito plays them the right time. But he's always struck me as a hunch type of Manager. Remember what he did did to Olerud at the end of his time here. At least we got Robert Person for him. Oh, wait...
- February 24, 2009 at 8:54 PM
- Wiffleballs said...
I get the feeling that J Mac's days in a Jays uniform are numbered...
- February 24, 2009 at 9:32 PM
So send him down if he wants, it's better for him than sitting his ass on the bench
I really don't want to have the Jays SS "learning" in the Majors. That would be what A ball is for.
- February 25, 2009 at 12:31 AM
J Mac is a great defender but can't hit worth a damn! Maybe the Yankees need a defensive replacement for Jeter, the Jays can get back/ extort a pitching prospect from that dope, Cash Man.
Otherwise, he could get a bag of ball for him!
Bruno Van Rottweiller
- February 25, 2009 at 10:31 AM
- eyebleaf said...
I hope Vernon has a monster fucking season. That is all. I'm tired of all the hating and negativity.
We're winning the mother fucking pennant.
- February 26, 2009 at 12:27 AM
- SP said...
Was Vernon really that bad last season in CF? I also don't know WTF those defensive metrics mean, but he wasn't THAT bad. They had him among the worst in the league. I'm betting a lot of his points off came because of that jittery start he had to the season, notably against Boston in early May. He still gets great jumps and reads. We still rarely see him dive, and we he did that one time he gets injured.
I'm still not ready to shut the door on Vernon as a CF. Rios has a great arm and all but it's like he has Outfielder's Autism out there. I don't trust him.
As for Bautista. CF and SS? WTF, is he BJ Upton? Didn't Joe Inglett prove that he could play last season? He should be our primary guy off the bench. I don't know why JP didn't just sign Moises Alou or Garrett Anderson instead of Bautista.
- February 26, 2009 at 12:10 PM


text:
Click below to filter your search results
Committee Opinion Number 678, November 2016
(Reaffirmed 2018)
ABSTRACT: Current sexuality education programs vary widely in the accuracy of content, emphasis, and effectiveness. Data have shown that not all programs are equally effective for all ages, races and ethnicities, socioeconomic groups, and geographic areas. Studies have demonstrated that comprehensive sexuality education programs reduce the rates of sexual activity, sexual risk behaviors (eg, number of partners and unprotected intercourse), sexually transmitted infections, and adolescent pregnancy. One key component of an effective program is encouraging community-centered efforts. In addition...
Committee Opinion Number 590, March 2014
(Replaces Committee Opinion Number 487, April 2011) (Reaffirmed 2018)
ABSTRACT: Patient care emergencies may occur at any time in any setting, particularly the inpatient setting. It is important that obstetrician–gynecologists prepare themselves by assessing potential emergencies, establishing early warning systems, designating specialized first responders, conducting emergency drills, and debriefing staff after actual events to identify strengths and opportunities for improvement. Having such systems in place may reduce or prevent the severity of medical emergencies.
American College of Obstetricians and Gynecologists
409 12th Street SW, Washington, DC 20024-2188
Mailing Address: PO Box 96920, Washington, DC 20024-9998


text:
North America
Many of our units, in the US in particular, partner with local charitable organisations to raise money or to collect necessities for the less-privileged people; whereas other units host events at SKF for the communities.
North America
SKF USA lends a helping hand
SKF USA supports the non-profit organization Habitat for humanity to build a new home for an underprivileged family in the local community.
Mexico: EHS Month
Sharing SKF's focus in environment, health and safety with the community
Mano Amiga - Computer classroom
SKF supports computer classroom construction with the local community development foundation...


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Thunderbolt Ski Museum in Adams tells 'significant' local story
Sunday December 9, 2012
The story of the Thunderbolt Ski Trail is a lively one, filled with Nazis, Olympians and world-class athletes -- both local and international -- skiing down a precipitous slope at hair-raising speeds.
And that story was mostly local lore until a group of historians, skiers and town officials made it accessible to the public by opening the Thunderbolt Ski Museum on Hoosac Street.
"This is one of the most significant local stories, and probably one of the most significant pieces of town history, that hasn't been told very well," said Adams Town Administrator Jonathan Butler.
Blair Mahar -- an educator, skier, filmmaker and local history aficionado -- came up with the idea for the museum in 2009, and he started it this past October with the help of friends.
About $12,000 in funds for the museum -- located in the former Berkshire Visitors Bureau building in Adams -- were provided by the town, the Adams Historical Society and private donations.
"It illustrates a pretty significant part of the town's history and the ski history of New England," said Eugene Michalenko, president of the Adams Historical Society.
The trail was built in 1934 on Massachusetts' highest peak -- 3,491-foot Mount Greylock -- by a unit of the federal Civilian Conservation Corps in response to the growing popularity of Alpine skiing in the United States. That's according to the archives of the Thunderbolt Ski Runners, the local entity that has maintained and promoted the trail.
The 1.6-mile trail, with steep grades of 35 percent in some spots, was named after the famous roller coaster at Revere Beach, also known for its thrilling, abrupt drops. Quickly, the Thunderbolt became known regionally, then nationally, and even internationally, as a first-class trail.
It was the site of the Massachusetts State Skiing Championships, several collegiate competitions, and the Eastern Championships from 1935-59. The latter was an open amateur race that attracted international competitors.
Olympians -- including two members of the 1936 U.S. team -- skied the trail, and two years later, a cadre of skiers from the University of Munich arrived in Adams to test the Thunderbolt at the Eastern event.
"They were German students, and they wore sweaters with swastikas on them," Mahar said. "And they kicked some butt."
It wasn't unusual for the Eastern Championships to attract 5,000 or 6,000 spectators, according to Eagle files. Special "ski trains" from New York City running directly to Adams were scheduled, according to Butler.
At one point, he said, Adams was known as "Little Switzerland'' because of the trail and the somewhat Swiss-style village at the foot of the mountain.
Several Thunderbolt skiers from the 1930s even became members of the U.S. Army's highly elite 10th Mountain Division that served in Italy during World War II.
"They were farm boys and factory workers from Adams," Mahar said. "According to the U.S. Army, there were 22 of them in the 10th, by far the largest number of skiers in the unit per capita."
The skiing craze waned in the post-war era, and by the 1960s and '70s, the mountain began to take back the trail as larger ski resorts, including Jiminy Peak, blossomed elsewhere in the Berkshires.
The Thunderbolt became a hiking trail, albeit a formidable one, but Mahar almost single-handedly revived interest in the mountain. He was intrigued by Mount Greylock's history, and in 1999 he produced a Greylock/Thunderbolt documentary titled "Purple Mountain Majesty."
"When I started looking into the history, I had no idea of its significance," Mahar said.
Mahar and the Thunderbolt Runners, along with other local ski clubs and individuals, rebuilt the trail and revived the Thunderbolt Ski Race in 2010. It was intended as a one-shot celebration of the renovation, but the event went so well -- attracting participants and observers totaling about 1,000 -- that it has become an annual race.
The next event will take place Feb. 9.
To reach Derek Gentile:
or (413) 496-6251.
On Twitter: @DerekGentile
Thunderbolt Ski Museum
Where: 3 Hoosac St., Adams.
Hours: 9 a.m. to 3 p.m., Monday through Friday, except holidays.
Admission: Free.
What you'll see: Exhibits honoring the "legends" of the trail, as well as ones featuring clothing, equipment and other memorabilia. Also, a documentary and films are shown on a regular basis.
If you'd like to leave a comment (or a tip or a question) about this story with the editors, please email us. We also welcome letters to the editor for publication; you can do that by filling out our letters form and submitting it to the newsroom.


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Branson is known for golf and is home to 12 of the finest championship golf courses! It is also one of the most beautiful settings you will ever see, with rolling hills and beautiful foliage. Hotels in the area are often more expansive than renting a vacation condo or home and you get extra space with a vacation rental! You can also cook all of your meals in your fully equipped kitchen-or go out if you would like to one of the many dining spots in Branson!
Here are some of Branson, MO vacation rental properties on golf courses:
Summersong Villa-A private 2 bedroom and 2 bathroom home located on the Payne Stewart Golf Course. This home is beautiful and includes a private deck, grill and is just minutes from downtown Branson. Included in this Branson, MO golf course vacation rental is a swimming pool, fitness room and wi-fi!
Firefly Haven- This 2 bedroom and 2 bathroom condo is located on the Thousand Hills Fairways Golf Resort. Relax in the screened in porch that overlooks the golf course, or take a dip in the resort's swimming pool! This is a highly recommended Branson, MO vacation rental condo!
Ozark Charm- Large 2 bedroom and 2 bathroom condo with private balcony facing the golf course! This condo is beautifully decorated and is sure to make your stay in Branson extra nice! This condo includes a private 2 person jacuzzi tub as well as access to a swimming pool, hot tub, tennis court, basketball court and a playground! Another top rated Branson vacation home!
This is just a few of the very nice vacation rental homes and condos in Branson, MO. If golf isn't on everyone's top priority list, there are a ton of other things to do in the great town of Branson! Music is another major attraction in Branson, MO as it is known as the "live music capitol of the world"! Shopping, boating, museums, theme parks, wineries, ziplines and more! Find out more at the Branson Chamber of Commerce.
PerfectPlaces.com has over 60,000 vacation rental properties in over 79 countries. Perfect Places is dedicated to helping travelers find and rent vacation rental properties worldwide. Vacation Rental properties offer a compelling alternative to Hotels for travelers seeking additional space, amenities and value that Hotels are often unable to match. Perfect Places is a privately owned company headquartered in Mountain View, California


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Studying for the LSAT / struggling with the LSAT« on: September 30, 2010, 12:32:41 AM »
Okay guys I'm writing my LSAT in December and I`ve been studying like crazy but im not getting the marks that i want (Average 145-150. I use Kaplan books, i have practice tests and I'm actually planning to get a one on one tutor to help me.
Do you guys have any suggestions as to how i should study or what books i should use?
Examples: Amount you study? How you study? Books? Courses? Strategies?
Thanks alot you guys and good luck with law school


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Pakistani Taliban claim responsibility for MQM MPA's killing
[Dawn] The Tehrik-e-Taliban Pakistain (TTP) has
grabbed credit
for the killing of a provincial
belonging to the
Muttahida Qaumi Movement
...English: United National Movement, generally known as MQM, is the 3rd largest political party and the largest secular political party in Pakistain with particular strength in Sindh. From 1992 to 1999, the MQM was the target of the Pak Army's Operation Cleanup leaving thousands of urdu speaking civilians dead...
(MQM), a
front man
for the banned outfit told Dawn.com on Thursday.
Gunmen on Thursday had
rubbed out
four people, including the MQM's provincial
Manzar Imam in
Bloody Karachi's
...formerly the capital of Pakistain, now merely its most important port and financial center. It is among the largest cities in the world, with a population of 18 million, most of whom hate each other and many of whom are armed and dangerous...
Orangi town area.
"A member of the Sindh provincial assembly was killed with three of his guards when
on two
cycle of violence
s intercepted his car in Orangi neighbourhood and shot them with automatic weapons," police
front man
Imran Shaukat said.
Police said the
expeditiously departed at a goodly pace
following the shooting.
In a telephone call to a Dawn.com correspondent from
Qazi's guesthouse
an undisclosed location
front man
for the TTP, Ehsanullah Ehsan,
grabbed credit
for the killing, saying it was the second targeted attack in
Bloody Karachi
that they had carried out on the political party.
According to an eyewitness, the MPA, along with his police guards was passing by Orangi town's Hyderi Chowk area when four
cycle of violence
s opened fire on the vehicle, reported APP.
Imam and one of his guards
bit the dust
on the spot, while the other two injured died while being treated for their wounds in the hospital, said the eyewitness report.
Imam was elected from the PS-95
Bloody Karachi
VII seat, and served as member on the Sindh Assembly's Standing Committee on Cooperation , Standing Committee on Environment and Alternate Energy and the Standing Committee on Prisons.
Posted by: Fred 2013-01-18


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|Authored By: Polly Pitchford, Full Spectrum Health
|Good for breakfast, dessert or snack.
|Diet Types: Dairy Free, Vegan, Vegetarian
|Serves: 4
|Cooking Time: Under 30 minutes
|Preheat oven to 400°. Place rice in a mixing bowl. Using a wooden spoon, break up any clumps of rice. In a blender or food processor blend together rice milk, cinnamon, flour, vanilla, and almond butter. Pour wet mixture into the rice and mix well. Transfer to a baking dish and bake for 45 minutes. Remove from the oven and allow to cool for a few minutes. Serve with almonds.
|Printable Version
|E-mail a Friend


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by Katie Parker, sports information graduate assistant
MILLEDGEVILLE, Ga. - The No. 31 Georgia College & State University women's tennis team (3-4, 1-3 PBC) fell 6-3 Friday afternoon to No. 4 Francis Marion University (6-0, 3-0 PBC) at the Centennial Center Tennis Facility.
The Bobcats started off strong in doubles action as the fierce French duo of Diane Danna (Paris) and Bertille Lion (Lyon, France) downed the No. 2 ranked pair of Tereza Sykorova and Sabina Baberadova 9-7. This was the first ranked duo for Danna and Lion to have beaten this season. Georgia College's first doubles team improved to 5-2 for the season, evening out their conference record at 2-2.
At second doubles, Bobcat freshmen Kayla Barksdale (Martinez, Ga.) and Michelle Lingner (Dunwoody, Ga.) surrendered 8-4 to Jitka Gavdunova and Mona Blauen. Giving the 'Cats a 2-1 advantage after doubles, Ariana Acuna (Peachtree City, Ga.) and Linda Mosa (Stockholm, Sweden) overwhelmed Kerry Hall and Karine Augur 8-2. This was the first doubles win for Acuna and Mosa for the 2010 campaign.
In singles action, Georgia College struggled as No. 6 Sykorova swept Danna 6-4 and 6-4 in the first slot. Despite splitting the first two sets with 6-3 scores, No. 26 Gavdunova blanked Barksdale 6-0 in the third set. At third singles, Lion lost 7-5 and 6-0 against No. 8 Baberadova. Lingner fell 6-2 and 6-3 to Blauen, while Mosa suffered the same fate against Hall in the No. 5 spot. Acuna continued her day of firsts, picking up her first singles victory for the season, shutting out Augur in two 6-0 sets.
The 'Cats are back in action this weekend, traveling to Savannah, Ga. Saturday, March 6 to take on No. 2 Lynn University and then on to No. 23 Flagler College Sunday, March 7.
The GCSU Department of Athletics, winners of the 2008-09 PBC Commissioner's Cup, sponsors 10 varsity athletic programs at the NCAA Division II level. As a Division II program, GCSU prides itself on balancing the life of the student-athlete, evidenced by the Bobcats' multiple appearances in post-season competition as well as documented academic success and community-service involvement. Sign up at Twitter.com username GCSUSID for up-to-the-minute reports, and visit www.GCSUBobcats.com to nominate your favorite former Bobcats and Colonials to the GCSU Athletics Hall of Fame.


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2019 Honda WRV. Though it is based on the Jazz, it gets multiple changes to create its own identity. It gets a high ground clearance, Larger wheels, sunroof and new audio system.It also gets a lot of cladding around that makes it look muscular and intimidating. It also comes with LED daytime running lights, keyless entry and cruise control. Thus it make for a very good choice. Honda's latest entrant in the subcompact SUV space, WRV has been enjoying popularity in the Indian market.
The proof of this lies in the fact that the compact SUV has crossed 16,000 sales mark with over 23,000 bookings within four months of its launch. Considering the high demand for the Honda WRV, the Japanese carmaker is planning to ramp up its production to 5,000 units from 3,400 units on the monthly basis. The current demand and production ratio has resulted into a waiting period of up to 2 months. The company aims to cut it down before coming festive season. With a total sales of 4,243 units in June 2018, the Honda WRV marked its entry into the top five best-selling utility vehicles of the month. The company has sold a total of 14,156 units (8,253 petrol and 5,903 diesel) of the compact SUV so far.
There are two engines available. One is a 1.2-litre i-VTEC petrol engine that produces about 88bhp of power and 115Nm of maximum torque. The gearbox has undergone some changes to deliver better performance this engine. The second id the 1.5-litre i-DTEC diesel engine that produces close to 98bhp of power and 200Nm of torque. This comes with a six-speed transmission. Read further to know more about the Honda WRV Price in India, Features, Specifications, Automatic, Mileage etc. There are only 2 variants and the Honda WRV comes up an exciting crossover to buy.
The number of features available are more than the Jazz, so it is an attractive product. So, the 2019 Honda WRV Price in India is higher as it comes with multiple changes over the hatchback. The base variant comes with dual airbags and ABS as a standard feature on them. This makes it a very good option to buy over some other competitors. The engines remain the same as the Honda Jazz. However, they are tuned differently to take the additional weight and deliver better performance. The petrol has better drivability and the diesel engine has got an oxygen sensor for the first time in any Honda car for India.
Unfortunately, there is no automatic variant available on the 2019 Honda WRV as of now. A good mileage is one of the high points about the 2019 Honda WRV. This crossover claims very good mileage figures. The 1.2-litre petrol mill returns close to 12-13 km/l in the city, while on the highway it is close to 16 km/l. On the other hand, the diesel engine should return close to 17 km/l in the city and about 22 km/l on the highway. The ARAI claimed mileage for the petrol engine is 17km/l, while for the diesel it is 26km/l. There is no petrol automatic on offering at the moment, but the company should soon be offering one with a 1.5-litre petrol engine.
Designed on the Jazz, the new 2019 Honda WRV gets a host of new elements that save it from being mistaken as Jazz's spin off. Featuring bold chrome band that runs between the pulled back headlamps, the upfront of the car looks similar to the BR-V. In addition, it gets a newly designed bumper that infuses aggression to the front profile. Unlike the front end, the side profile gets some Jazz resembling elements. It has borrowed the side panels, character lines, doors and window shape from its donor hatchback sibling. Though, Honda has added new bits such as new roof rails atop, plastic cladding on the lower body, new diamond cut alloy wheels and flared wheel arches. Round the back, Honda has used new design cues that give it a new identity. What enhance its sporty appearance are the L-shaped taillamps, new tail-gate and the dual tone bumper.
In addition, the license plate has been repositioned a tad that sets it apart from its donor hatchback. Honda has altered the dimensions in a bid to provide more space on the inside. The overall length of the car measures 3,999mm, while its width and height stand at 1734mm and 1601mm respectively. The wheelbase at 2,555mm makes for a spacious cabin to accommodate five adults. Ground clearance is around 188mm and the luggage compartment is 363-litres large. Unlike the exterior styling, the SUV carries almost same elements as Jazz save for some new bits. It not only gets similar styling but it also sports same layout.The quality of material used on the rear seats is neither too hard nor too soft that makes it very comfortable to use.
Changes made to the dimensions make the interior more comfortable in terms of space. The cabin with increased proportions allows space for five adults. The driver's seat in front, is well-cushioned and offer great thigh support, back support and gets a height adjuster. While there is enough headroom in front, the rear side offers better leg room and knee-room. Comfort goodies such as automatic climate control with touch control panel, one push start/stop button, smart key with keyless remote, keyless entry & central door lock, driver side power door lock master switch, all power windows with key-off time lag, cruise control, power operated ORVM with power folding function, front centre armrest with storage console, accessory charging ports with li etc are packed in the SUV. Utility space on the inside includes bottle holders on front and rear doors, cubby holes, front seat back pocket, glovebox etc.
The front armrest in front also comes with storage space and there are two cup holders in the front console box. Connectivity features such as the integrated 8.9cm audio with AUX-in port, 7.0-inch DIGIPAS touchscreen infotainment system, in-built satellite linked turn-by-turn navigation, My storage internal media memory (1.5GB), Mirror Link, internet access for browsing etc, voice commands for media navigation and calling are available with the SUV. Along with these, it also comes with smart phone voice assistance activation, Bluetooth for handsfree telephone and audio streaming support, USB-In ports, HDMI-In ports, micro SD card slots, AM/FM, digital tuner, MP3WAV, i-Pad/i-Phone, steering mounted controls for audio & voice are also a part of the pack.
On the outside, it gets pulled back headlamps with integrated DRLs, electric sunroof, 16-inch alloy wheels, rear washer & wiper, fog lamps etc among others. While on the inside, it gets tilt & telescopic adjust for steering wheel, multi-information combination meter with LCD display etc. Compared to the Jazz, the subcompact SUV is 44mm longer, 40mm wider and 57mm taller. In addition, the wheelbase has been increased by 25mm and the ground clearance has also been raised by 23mm. With these changes, the SUV offers decent room inside the boot that stands at 363-litres.
With the implementation of the GST tax regime, the 2019 Honda WRV received a price cut of around Rs 10,000. The revised pricing for WRV falls between Rs 7.66 lakh to Rs 9.91 lakh compared to the previous prices that ranged between Rs 7.75 lakh to Rs 9.99 lakh (all prices ex-showroom, Delhi). Based on Honda's premium hatchback Jazz, the sub four-meter SUV carries crossover like styling bits. The vehicle not only shares most of its design features and underpinnings with the Jazz, but it also uses the same set of engines that power the premium hatchback. The 2019 Honda WRV line-up comes with the 1.2-litre, i-VTEC petrol and 1.5-litre i-DTEC diesel engine with a choice between two manual transmissions.
You are viewing 2019 Honda Wrv video mileage vs brv, picture size 800x408 posted by Administrator at August 17, 2017. Don't forget to browse another digital imagery in the related category or you can browse our other interesting digital imagery that we have. Please also read our Privacy Policy and DCMA for the copyright of the images.Back to 2019 Honda WRV Specs Update And Price


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THE UBIQUITY OF PASSPORT covers in South Korean shops speaks volumes to this society's new internationalism. Spending a month in the outskirts of Newcastle to do an MBA program or jetting off to Vancouver, B.C., for an English-language course have become commonplace adventures — necessary to reach a level of relative success. Coming across a cover that communicates a matching sense of class to customs agents, however, is less frequent.
I picked up this hand-sewn, goat leather passport cover by designer Park Jin Ok (or "Janey," as is stitched on the detail tag) in the homewares section of A Land in Seoul's Myeongdong district on a recent shopping trip. The way the corners don't exactly match up gives it a rough-edged DIY feel that contrasts nicely against the material's baby-softness; the small inner pockets are handy for keeping track of train, ferry and plane tickets. The truffle brown color of the leather is classic, and will show the nicks, stains and wear from the years' travels.


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**** in Zebegeny max. 4 Persons
Holiday Rentals for rent
per week from 3,977.29HRK (534.00 EUR)
hu- Zebegény
Available according to agreement
|Firma Bungalow.Net BV
NL 8011 Zwolle
|All offers of the estate supplier
per week:
from 3,977.29
Zebegény is situated on the most beautiful part of the Danube Belt, 60km from Budapest. With its unique beauty and atmosphere, it has become a popular holiday resort. Here each season offers a unique ambiance. Zebegény has two parts: the village, which lies in the valley, and the chalets, which are nestled among the mountains. This accommodation is located on top of a mountain, in the most tranquil and beautiful part of Zebegény. The house is accessible in both summer and winter. Due to its unique location, the whole Danube Belt `lies in front of its base`. The house itself was built in 2006, in Mediterranean style. It contains 5 apartments, each designed to provide a beautiful panoramic view, which can be enjoyed almost from your bed. The furnishings guarantee total comfort.
Next to the house there is a parking place for your car as well as a beautiful well-looked-after garden. The garden comes with outdoor furniture and a barbecue.
Suburban traffic
Zebegény is situated between Visegrád and Esztergom, in the middle of the Danube Belt. Its magic casts a spell over everyone who visits it. This is due partly to the beautiful layout of the tiny village, but its cultural traditions and approachability are also key factors in its charm.
Designed by the famous Renaissance man Károly Kós, the Roman Catholic Church in the village is well worth seeing. It is also a unique example of 20th century Hungarian church construction. The Maritime Museum is also quite interesting.
Here each season of the year provides a different atmosphere. In the warmer seasons there is the opportunity for water sports, angling, horseback excursions, tennis, football, volleyball, etc. In winter ski aficionados will find a slope with ski-lift in Zebegény–Újvölgy. From Zebegény there are cruises to Esztergom and Visegrád every day.
Zebegény is an ideal place from where you can take excursions to the capital of Budapest (60km) or Esztergom (25km), which used to be the capital of the country during the reign of Arpad. Its famous dome-topped cathedral as well as neighboring Visegrad (10km), which is one of the oldest towns in Hungary, are a must see. In Visegrad you will find the ruins of the renaissance Royal Palace. On top of the mountain above the palace there is a spectacular medieval fortress and a toboggan run. Visit Szentendre (30km) where the local gallery and the Margit Kovács Museum are worth seeing.
This a modern, completely-furnished Mediterranean-style apartment suitable for four persons. The apartment has well-arranged bedrooms, a kitchen and a living room. Each bedroom is furnished with a double bed. There is a well-equipped American-style kitchen and a living room containing a satellite TV and CD player. The beautiful bathroom has a wash basin, toilet and bathtub.
Possibility nearby / Möglichkeiten in der Nähe: Horseriding, Fishing


text:
Wednesday, June 29, 2011
My Harry Potter Rant
It's tough for me to objectively judge that experience in retrospect as I was already fairly bound and determined to dislike whatever came on the screen and recalling the company I kept for those two and a half hours does the memory no favors. I decided then and there I would have nothing to do with the little wizard boy and his adventures moving forward.
This was a vow I stuck by with vigor despite the turns my life took over the past decade. New friends who want to make an evening of seeing the new Harry Potter? Have fun, nerds, I'll stay home and read comics. Date and marry a girl who loves the books and movies? I'll practically pay Jim McCann to drive over and see the latest with you while I go to Transformers—lesser of two evils? History will decide—darling. Kevin comes to work in full glasses, school boy and drawn-on scar costume for no reason? Well, that anecdote really doesn't match up with the others, but it totally happened and I'd be remiss if I didn't bring it up every chance I get.
But with time and love, I suppose we all grow a bit softer and put aside our childish wars. It was with this maturity and boundless generosity that I made the following deal with my wife: I would watch all the Harry Potter movies with her before the last one came out so I could go see it with her and her friends.
And I did it. Yes, I am that awesome a husband. There was a second part of the deal that stipulated she was to watch all the Rocky movies with me, but that seems to have fallen to the wayside…
Anyhow, what do you know, those movies aren't too bad. Hey, I'm not saying they're masterpieces and I don't think I'll be re-watching them any time soon—the last one was crazy dull—but the stories are wildly creative, the acting is pretty uniformly strong and the visual world brought to life is remarkable. I have to commend everybody from the lady who wrote the books to the cast to every crew member for entertaining me for more than a few hours and not losing my focus. I really do have tremendous respect for the folks responsible for this franchise.
However, there is no question much of my enjoyment has also come from the ability to point out huge, gaping holes in logic that my lack of emotional attachment to this material has gifted me with.
I give you now, as best I can remember it, the inspired tirade I went on directed at the aforementioned Kevin in a public New York City park across the street from Marvel as we lunched that addressed the central flaw in the world of Harry Potter and drew the attention of more than a few concerned onlookers…
Say you run a school and you've got a profiler—maybe a person, maybe a hat—that is able to ascertain whether a young person is innately good or evil with beyond scientific accuracy. Let's further suppose that your profiler identifies a solid quarter of your student body as having the propensity for wrongdoing, across the board from troublemaking bullies to potential serial killers. Do you, say, expel the kids who are going to turn out bad so as to not have them reflect poorly on your institution/train them in skills that will aid them on their dark path? Barring that—maybe it's too harsh—do you at least spread them out, apart from one another, where hopefully they can receive good influences from kinder associations? Do you have your staff pay special care to watching out and making sure they don't tend toward the wrong side? Or do you PUT THEM ALL TOGETHER IN ONE PLACE AND LET THEM ENCOURAGE EACH OTHER TOWARDS BEING BAD GUYS WHILE DOING NOTHING TO STOP IT?
If you answered the third option, congratulations, you're the new headmaster at Hogwarts.
I can't hammer home the point emphatically enough and will once again resort to CAPS lock in order to at least try: HOGWARTS HAS A FRATERNITY THAT ONLY PRODUCES EVIL WIZARDS AND IS RESPONSIBLE FOR EVERY BAD PERSON WHO HAS EVER MENACED THE WORLD AND YET THEY KEEP IT OPEN AND ADD IMPRESSIONABLE YOUNG PEOPLE TO IT EVERY YEAR.
Also, the school should have been shut down years ago for endangering students and the time travel sequence in the third movie has massive functional problems.
For the most part though, fun movies! We'll see if I still feel that way after I have to go to the theme park in August…
11 comments:
- Zach said...
Completely wrong.
Slytherin doesn't produce only evil Wizards. Professor Slughorn is not evil in the slightest. Andromeda Tonks, mother to the Tonks we see as a member of the Order, is also a Slytherin and helped hide Harry from Death Eaters. Regulus Black turned on Voldemort and tried to destroy one of his horcruxes.
Slytherin isn't completely evil, it's just home to cunning, ambitious and sneaky wizards and witches. The reason so many of the Death Eaters come from Slytherin is that A) Voldemort came from that house, so he knew other members and recruited from there and B) They are big on racial purity, and Slytherins tends to have fewer muggleborns.
You also state that they are responsible for every bad wizard that ever menaced the world. Not at all true. Grindlewald, the most feared dark wizard of all time until Voldy shows up 50 years later, wasn't a member of Slytherin. He wasn't even a student at Hogwarts! Igor Karkaroff, another foreign wizard, was evil and not from Slytherin.
Also, why would you shut down the school for endangering children? The Potterverse is full of actual goddamn monsters. Losing a kid or two to a basilisk is pretty minimal in a world where actual giants roam the earth and frigging vampires hang out in taverns.
This is a super-flawed article, Ben.
- June 29, 2011 at 8:27 PM
- Ben Morse said...
You're a super flawed article.
- June 29, 2011 at 8:29 PM
- Zach said...
So no chance you're gonna change the article to reflect actual facts instead of just posting incorrect assertions?
- June 30, 2011 at 10:37 AM
haha fucking muggle nerds
- June 30, 2011 at 1:30 PM
- JimmyGlenn711 said...
That line is hysterical. I very literally laughed out loud! This is a very good point about Slytherin.
In response to the commenter above, its a fair point that all of the evil in the Harry Potterverse doesn't come from Slytherin, but regardless they still do encourage impiety.
- June 30, 2011 at 6:49 PM
- Zach said...
Jimmy, it's in fact a very bad point, for the reasons I stated above.
- June 30, 2011 at 9:02 PM
- Ben Morse said...
Zach, I thought the tone of the article made it fairly clear, but I do not know much about Harry Potter and did not pay a lot of attention when I was watching the movies. I can't understand half the words in your response. I apologize if you thought you were reading a serious critique here, but my tongue was firmly in cheek while writing this.
- July 1, 2011 at 7:05 PM
- Megan Morse said...
Dear Zach,
Lighten up.
- July 1, 2011 at 7:06 PM
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- April 21, 2017 at 3:52 AM
- Deepak Yadav said...
Really a nice post and opinion you shared with us. Well When I saw Harry potter first movie than I think this movie is story of common boy. At that time I did not know about much more about the movie. But later I impressed with all of the series of Harry potter movies.I enjoy all of them with my friends. Usually I watch online movies at home.
- December 16, 2017 at 12:21 AM


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The cover story of the January 2013 issue of ASBMB Today reports on the results of a recent ASBMB survey of young biochemists and molecular biologists. In a sidebar, Fred Maxfield of Weill Cornell Medical College, who leads the ASBMB committee focused on mentoring, writes about what the respondents had to say regarding the advice they receive. Also in this issue are preview articles about the 2013 ASBMB Special Symposia lineup. And, for those of you uncertain about how using certain social media tools can benefit you personally and professionally, Rajini Rao of the Johns Hopkins University School of Medicine offers a testimonial on the value of Google Plus.
In the February 2013 issue of ASBMB Today, our personal essay series "Derailed but Undeterred" launches with a piece by Wendy Knapp Pogozelski called "The uses of metabolic adversity." For the cover story, "The other malaria parasite," we talked to researchers studying the ill-understood parasite that causes most malaria cases outside of Africa. Meanwhile, in the mentoring column, Jim Keen offers some advice for those just embarking upon a life of academic research. And contributor Cristy Gelling interviews artist and science student Maja Klevanski, who sees structures in the Protein Data Bank in very unique ways.
In the March 2013 issue of ASBMB Today, the second installment of our personal essay series, "Derailed but Undeterred," is by Martha Lewis, who fled Sierra Leone as a child and now is pursuing a career as a physician–scientist. You'll also find the first part in our two-part coverage of the society's annual award winners. Look for others in the April issue. In the minority affairs column, Squire J. Booker writes about making careers in science accessible for those with disabilities. And we have news items from the ASBMB journals.
In the April 2013 issue of ASBMB Today, the third installment of our personal essay series, "Derailed But Undeterred," is by Aditi S. Iyengar, who writes candidly about the highs and lows of graduate school. You'll also find the second part in our two-part coverage of the society's annual award winners. Our cover story reviews what is known about the molecular underpinnings of Alzheimer's disease and offers perspectives from two women caring for their declining mothers. In an online exclusive article, contributor Connor Bamford talks to scientists studying triple-negative breast cancer, an area of research that will be given special attention at the ASBMB annual meeting later this month.
In the May 2013 issue of ASBMB Today, we explore what we know — and what we need to know — about sperm and how it relates to male infertility. The fourth and fifth installments of our personal essay series, "Derailed but Undeterred," are by Christine Guthrie, who candidly tells how she prevailed through a particularly dark period when she was a young investigator, and by Jonathan Gitlin, who recalls the challenges he experienced as a noncitizen forging a career in U.S. science policy. You'll also find a Retrospective article about the late Wm Wallace "Mo" Cleland and a feature by contributor Diedre Ribbens about the uptake of digital PCR by some researchers seeking to solve certain types of problems. And don't miss our Journal News highlighting two new minireviews in The Journal of Biological Chemistry, a thematic series on microRNAs in the Journal of Lipid Research and a special issue of Molecular & Celullar Proteomics focused on glycoscience.
In the summer issue of ASBMB Today, we explore the mysteries of spider pheromones with a Q&A with Stefan Schulz. ASBMB President Jeremy Berg reviews the National Institutes of Health's BRAIN initiative. And contributor Lola Olufemi offers ideas for reducing laboratory expenses. Meanwhile, in this month's installment of the special essay series "Derailed but Undeterred," Bethany Brookshire, a blogger for Scientific American more commonly known by the moniker Scicurious, writes about her experience with imposter syndrome. As a reminder, ASBMB Today will resume monthly publication in August.
The August 2013 issue of ASBMB Today is more jam-packed than usual, and it promises to have a little something for everyone. In our Brown Bag special section, we offer news, advice and perspectives about various aspects of work and school. This month's captivating contribution to our ongoing personal essay series is by Harvey "Jim" Armbrecht, who writes about his wife's diagnosis of Lewy body disease and about the SAMP8 mouse, a model for early memory loss. We also offer a profile of the University of Pennsylvania's Virginia Lee and launch our new Point/Counterpoint column with Eleftherios P. Diamandis and Peter J. Kennelly providing their perspectives about paying peer reviewers. In the President's Message, Jeremy Berg explores what a sustainable biomedical enterprise might entail.
The cover story in the September 2013 issue of ASBMB Today is about investigators who are juggling the demands of laboratories in two places at once. We have two Career Insights articles: one about how to compete with those lab diva-types and one about how to conduct salary negotiations skillfully. Contributor Lauren Amable profiles artist Lynn Fellman, who has embraced her new role as a biological science illustrator, and contributor Kamalika Saha interviews ASBMB member Ritankar Das, who graduated from the Universtiy of California, Berkeley, at the top of his class — at age 18. In addition, David J. Kroll, a columnist for Forbes magazine, writes about the work environment and science-outreach efforts at the North Carolina Museum of Natural Sciences, where scientists do their research in full public view. Last, but not least, we hope you'll consider submitting an open letter for our forthcoming series.
The cover story of the October 2013 issue delves into what we know about protein evolution and explores the debate over whether function or structure first arose in primitive peptides. This month's Derailed but Undeterred contribution by F. Peter Guengerich marks the end of the personal essay series. For job-seekers and new (or struggling) managers, we have two Career Insights articles: In the first one, seasoned lab managers offer their advice on how to run a research group; in the second, Bill Sullivan provides do's and don'ts for postdoctoral application cover letters. Lastly, don't forget to submit an open letter for our forthcoming series, Open Letters. The deadline is Dec. 31.
The cover story of the November 2013 issue offers a big helping of food for thought. Intrigued by a message on her favorite pizza chain's packaging, science writer Rajendrani Mukhopadhyay dared to ask the experts, "Is the glycemic index a useful measure of carbohydrate metabolism?" The answer, it seems, depends upon whom you ask. In the education column, members of the ASBMB Research Coordination Network steering committee introduce a forthcoming toolkit for BMB educators. And contributor Mark Stewart writes about the rewards and perils of using crowdfunding to finance research projects.
The cover story of the December 2013 issue features Hudson Freeze, a winner of the 2013 Golden Goose award for the discovery of Thermus aquaticus. Contributor Thomas E. Schindler offer a heartfelt essay about how his family dealt with a devastating diagnosis for their daughter: stage IV neuroblastoma. (Spoiler alert: His story has a happy ending!) And, just for fun, we collected tweets from biochemistry and molecular biology students about their favorite and zany professors. (Profs, don't be scared!)
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Beach HP Athletes Competing at Championships
B.J. Hoeptner Evans, Manager, Communications, Phone: (719) 228-6800, E-Mail: email@example.com
USAV Facebook - @USA_Volleyball - @USAV Beach
COLORADO SPRINGS, Colo. (May 3, 2013) – Sand volleyball teams from colleges around the country have converged on Gulf Shores, Ala., for the AVCA Collegiate Sand Volleyball National Championships, which run May 3-5.
| Kirby Burnham receives the ball as partner Jace Pardon watches
at the 2012 FIVB Beach Volleyball U21 World Championships.
The Gulf Coast Region of USA Volleyball is one of the hosts of the event. USA Volleyball is also sending staff members to help at the event and providing top beach volleyball event director Matt Gage to help keep the competition running smoothly.
Pepperdine University, Long Beach State University, University of Southern California, University of North Florida, Florida State University and the University of Louisiana-Monroe are the schools that have been selected to compete in the team championship.
The 16-team pairs field includes the top duos from the schools in the team competition as well as 10 doubles teams from schools not in the team competition. Pairs were selected from Georgia State University, University of California/Los Angeles, Florida International University, the University of Alabama/Birmingham, the University of the Pacific, Jacksonville University, Loyola Marymount University and Saint Mary's College of California. All participants in the championships were selected based on results from the collegiate sand volleyball season that began in March.
Many of the athletes competing in Gulf Shores have USA Volleyball connections as well.
From top-seeded Pepperdine: Lara Dykstra (Redondo Beach, Calif.) competed at the FIVB Beach Volleyball U19 World Championships in 2008 and 2010 with UCLA's Rebecca Strehlow (Long Beach, Calif.), who is also competing in Gulf Shores. In 2010 the pair became the first U.S. girls' team to make it to the U19 World Championships main draw. They also won the U19 division of the 2010 USAV Beach High Performance Championships. Both are current members of the U.S. U23 Beach National Team, as is Caitlin Racich (Santa Barbara, Calif.), who competed at the 2011 FIVB U21 World Championships. Other Pepperdine athletes currently training with the U.S. Beach National Teams are Taylor Racich (Santa Barbara, Calif.), Kim Hill (Portland, Ore.) and Lilla Frederick (Huntington Beach, Calif.).
From No. 2 seeded Long Beach State University: Tara Roenicke (Alta Loma, Calif.) won the 2010 FIVB U21 World Championship with Summer Ross (San Diego, Calif.), with whom Roenicke also won the 2008 Australian Youth Olympics Games. Roenicke has competed in a total of four U19 and U21 FIVB World Championships and finished fourth at an FIVB exhibition tournament in Pusan, Korea. Caitlin Ledoux (Phelan, Calif.) finished fifth at the 2008 FIVB U19 World Championships with Roenicke and finished fourth with her in Pusan, Korea. She also competed at the 2010 and 2012 World University Championships, finishing fifth in 2012 with graduated University of Southern California sand player Geena Urango. Ledoux and Urango won the gold medal at the 2012 USAV Beach HP Championships. Long Beach State's Jocelyn Neely (La Habra, Calif.) competed at the 2008 FIVB U19 World Championships with Dykstra and has trained with the U.S. Beach Volleyball Team along with Beach teammate Chelsea Carbajac (Downey, Calif.).
From No. 3 seeded Florida State: Jace Pardon (Manhattan Beach, Calif.) played at the 2012 FIVB U21 World Championships with Kirby Burnham (Newport Beach, Calif.) of USC. Pardon won at the 2012 USAV Beach HP Championships with Litara Keil (Long Beach, Calif.) of Loyola Marymount. Aurora Davis (Groveland, Fla.), Stephanie Pellitteri (Deerfield Beach, Fla.) and Kristina Pellitteri (Deerfield Beach, Fla.) have all participated in USAV Beach High Performance Programs.
From No. 4 USC: Along with Burnham and Pardon, Alexa Stonish (Stony Brook, N.Y.), Eve Ettinger (Santa Barbara, Calif.), Cinnamon Sary (Newport Beach, Calif.), Stevi Robinson (Hermosa Beach, Calif.), Sydney Seau (Dal Mar, Calif.) and Kati Duddridge (Santa Ana, Calif.) have all participated in USAV Beach HP events and programs.
Lane Carico (Manhattan Beach, Calif.) of Georgia State and Dalas Dodd (Manhattan Beach, Calif.) of St. Mary's have both competed at the FIVB U19 World Championships for the United States.


text: On July 2nd 2009 at the ICN congress in Durban, South Africa, members of the Rural and Remote Nursing Network's core steering group met with and listened to hundreds of nurses that expressed concerns related to rural and remote nursing. This meeting provided a wonderful opportunity for nurses across the globe to voice their concerns to the core steering group. The group took notes and spoke briefly about how they hope to make the network more active, increase communication venues, and increase list serve membership. The core steering group inform the ICN of problems that need to be addressed in rural and remote areas, ultimately providing the framework for some of ICN's initiatives.


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A Suitor for Time Warner Cable?
Charter Communications is nearing an agreement with banks to borrow money for a bid for Time Warner Cable. WSJ's Dana Cimilluca joins MoneyBeat with details. (Photo: Getty)
This transcript has been automatically generated and may not be 100% accurate.
... ay ay mm mm mm mm ... welcome to MoneyBeat It's from and Paul vignette Charter Communications is nearing an agreement with banks ... to borrow money for a bid for Time Warner Cable ... Wall Street Journal get the MNA Editor Jamison Deluca reported this betrays ... Wall Street Journal an e joins us now to talk about it ... Dana I ... this is kind of interesting the number for going after number two ... they're interesting and I'm ... you know Charter is his answer is this cable company ... was not an ordinary cable companies have the backing of John Malone who was a pioneer ... in in the telecommunications industry and in an unnamed particular in the cable sector so ... that charters got his backing so the summit house be taken seriously but it but you rightly point out ... Charter's considerably smaller than time once the staff when aggressive move on their part no getting it done while in making this aggressive ... like to this day they there is that there's a very strong belief among Malone people around him and others in the industry did did did did in the cable industry given the challenges that these companies are facing scales very important right now ... particularly ... on scaled enables you to negotiate better deals with the programmers to buy content from ... right ... that said I understand it changing fire in all these things you still can open number for buying into how the income of the money or the will to come up with enough money to satisfy shareholders ... even if the sheep that is similar to ... how far is the can it be for another four to digest the number two on the keys to wear what gamble on is that is is nothing if not a deal maker so they certainly have plans for how they can put those two nominees together at the bigger question is how they find it and I were the crux of our story today it appears to getting close to lining up the debt package newbie knows how big the analysts speculated maybe need fifteen billion in debt ... the other factor keeping mines they have a number of other potential sources of funding have charter shares ... giving other possible in the race in the story today which is equity from outsiders like sovereign wealth funds and in you have cash on Liberty Media's balance sheet which probably they would take an ... honest heart be also ... and I'd I'd I'd I wonder leaving one else AOL time Warner's him playing time Warner Cable ... maybe we wanna get involve this you know it's a great question one one one point we brought upon our story is should this happen you could buy costly kick off a wave of consolidation the sector for some other reasons I discussed before ... and and this morning it's there for saying that aam Comcast might be eyeing the situation ... it's certain ... that if they did try to do something with Time Warner you be putting number one and Number two together and in this environment you gotta believe and trust cops to take it very hard look at her right so bottom line is ... on Friday to see some action in the sector ... near future that is decent ... what the actual am ET PT we all know what killed the action ... looks like a news report but so be it takes a lot ... of all


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Four Iraqi children were killed on Wednesday as they walked to school in central Baghdad. The children were killed by a roadside bomb which targeted a liquor shop in Baghdad, according to sources at Iraq's Ministry of Interior. The liquor shop was reportedly destroyed and several surrounding buildings badly damaged, according to the AP. Similar attacks on liquor stores by religious groups have been frequent in Iraq. The dead included two sisters and their brother.
At least 14 other people, including six policemen, died in car bombings and shootings across the Iraqi capital.
At least three car bombs went off across the capital Wednesday, targeting police but also killing two Iraqi civilians and injuring several others. A parked car bomb went off as a police patrol passed by, killing four policemen and injuring two civilians in northern Baghdad, Lt. Nadhim Nasser said.
Another car bomb killed two civilians near Baghdad's University of Technology. That attack also injured five people, including three policemen.
A third explosives-rigged car blasted near a gas station as an Iraqi police patrol passed in downtown Baghdad's Karradah area, injuring five policemen and three civilians.
Gunmen firing from two cars shot and killed a police captain and his driver, also a policeman, in Baghdad's Sadiyah neighborhood, said police Lt. Aqil Fadil, according to the AP.
Police also said they found the bodies of five men shot in the head and dumped near a Shiite neighborhood of western Baghdad.
Another civilian was shot dead in a drive-by shooting in western Baghdad's Ghazaliyah district, police said.
Meanwhile, Iraqi police reported that a five-year old boy was among the eleven family members killed on Tuesday by gunmen in the town of Balad, north of the capital.
The family was reportedly rounded up and then shot dead by gunmen on a farm in the Shiite town, according to Reuters. The gunmen then escaped in the family's truck.
15-year-old Gazwan Hussein, whose father, Sheikh Hussein Sarhan al-Hiyali, had been killed in the attack, was wounded but not killed.
He told reporters from his hospital bed, "When we arrived at the farm at about 8 a.m., we were ambushed by nine gunmen who were covering their faces. They told us to sit down. When my father tried to pull the pistol from the pickup truck, they opened fire immediately."
Also on Tuesday, US military sources reported that gunmen killed an Iraqi army major and his son near A-Taji, north of Baghdad. An Iraqi contractor working with the Iraqi army was also killed by gunmen in the town of Tikrit.
Elsewhere on Tuesday, a police colonel was wounded in a failed assassination attempt on his life by gunmen. The men reportedly opened fire on his car in the central Iraqi town of Baquba.
© 2006 Al Bawaba (www.albawaba.com)


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Facebook safe-sex campaigns help prevent sexually transmitted diseases, at least for a while, according to a new report.
Scientists at the University of Colorado recruited 1,578 young African-American and Latino adults between 18 and 24 a project on condom use, one of the mainstays of preventing sexually-transmitted diseases, the Toronto Sun reported. Some of the participants signed up on a Facebook page called Just/Us which focused on condom use, sexually transmitted diseases and how to discuss sexual history with one's partner. (Other participants signed up for a Facebook page called 18-24 News, which shared news items of aimed at their age group and served as a control group.) The original article appeared in the American Journal of Preventative Medicine.
After two months 68 percent of those signed up for Just/Us said they used condoms in their last sexual encounter, while only 56 percent of the control group reported condom use.


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Nutrition Facts
Ingredients and Preparation
- Cook the pasta according to package directions, omitting salt and fat.
- Heat oil in a large deep skillet over medium heat. Add garlic and sauté about 1 minute, until fragrant. Stir in tomatoes and continue cooking another minute.
- Add pasta to skillet, and toss to coat with tomatoes and garlic. Stir in basil and remove from heat.
- Toss pasta mixture with mozzarella and serve immediately.