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Clinical Research In India
People With Autism Have More Symmetrical Brains. Here's What That Could Mean
In spite of how they appear, the left and right hemispheres of the human brain tend to be far from perfect reflections of each other. Some neurological disorders can affect that imbalance, causing the two halves to appear strikingly alike.
So far, studies on whether autism is among those conditions have been less than convincing. To get a more definitive answer, researchers analysed thousands of brains and showed there is slightly more symmetry for those on the spectrum.
But what does that really mean?
To get this answer, scientists from the Enhancing Neuro-Imaging Genetics through Meta-Analysis consortium collected decades of brain scans from more than 1,700 individuals diagnosed with autism spectrum disorder (ASD) and more than 1,800 with no diagnosis.
The consortium were hardly strangers to analysing huge banks of data, having only recently conducted a similar study on ASD brain anatomy involving more than 3,000 subjects.
The condition covers a spectrum of characteristics that can make life a little more challenging for some, affecting their ability to socialise, communicate, and process stimuli.
With such variation in behaviours, sensations, and impact, tracing the traits making up ASD down to simple neurological differences is no easy task.
Doing so could help make the disorder easier to diagnose and lead to novel therapies, opening the way to providing better methods of assistance for those who need it.
So researchers have been busy looking for clues on all levels of anatomy, from the genes to the gross architecture of our squishy bits.
There have been plenty of investigations into the overall structures of autism-related brains, discovering subtle differences such as the thickness of the cerebral cortex and how key areas link together.
Comparing the ways our brain's mirrored hemispheres reflect each other is a fair way to understand how they develop and communicate.
After all, for most of us, it's differences both between and within the two halves that governs everything from movement to cognitive processes.
Unfortunately, there's still so much we don't know about this contrast between the hemispheres, or 'lateralisation'. So when it comes to learning how lateralisation might be linked with more profound neurological differences, we're still in the dark ages.
There are studies that have found people with ASD have unusually symmetrical brains. There are also studies that found no such thing.
They also tend to be more left handed, and seem less symmetrical in other areas of the brain.
If you're confused about what to make of the mess of conflicting studies, you're not the only one.
"Previous studies have suggested that people with autism spectrum disorder are less likely to have the typical asymmetries for language dominance or hand preference," says geneticist Merel Postema from the Max Planck Institute for Psycholinguistics in the Netherlands.
"However, it has not been clear whether asymmetry of the brain's anatomy is affected in autism, because different studies have reported different findings."
Comparing the thickness of the cortex forming key parts of the brain's outer layer, the researchers found there was comparably less variability across the hemispheres in brains from people with ASD.
These differences didn't vary much depending on sex, medication, or IQ, making it more likely that there was something about autistic brains that accounted for this increased symmetry.
In spite of the significance of the results, it's not enough of a difference to base a diagnosis on.
"The very small average differences in brain asymmetry between affected people and controls mean that changes of brain asymmetry will not be useful in terms of clinical prediction", says the study's leader, Clyde Francks from the Max Planck Institute for Psycholinguistics.
"But the findings might inform our understanding of the neurobiology of autism spectrum disorder".
Some of the differences, for example, appeared in areas containing networks that work harder while we're resting. Just how this might account for some of autism's traits – if at all – is a task for future studies.
No doubt, there'll be more research on this in the future. Having more information on how our brain works as a whole not only helps us better understand how ASD arises, but how behaviours and functions common to all of us might develop.
This research was published in Nature Communications.
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ICMR and LSHTM join hands to train healthcare professionals on use of diagnostics in prevention & control of AMR
The London School of Hygiene and Tropical Medicine (LSHTM) and Indian Council of Medical Research (ICMR) have joined hands to train healthcare professionals about the use of diagnostics in the prevention and control of antimicrobial resistance (AMR).
Health professionals, students or anyone who is interested to learn about the use of diagnostics in the prevention and control of antimicrobial resistance (AMR) can enroll on a first come first served basis.
This is a six week online training course developed by LSHTM.
Training will cover Clinical Syndromes, Healthcare Associated Infections (HAIs), Enteric Infections and Drug Resistant Infections in TB and Role of Diagnostics in AMR.
It will also cover basic concepts of microbes, colonization and infection as diagnostics play a major role to respond to the increased threats being posed by overuse of antibiotics.
It will focus on four bacterial pathogens that cause enteric or food- borne infections in humans and animals and the need to use diagnostics for the prevention and control of AMR.
This will includes Enteric infections, Salmonella spp., Shigella spp. and Escherichia coli.
It will also discuss the role of diagnostics in the detection and surveillance of drug resistance for Mycobacterium tuberculosis and Neisseria gonorrhoeae, two pathogens of public health importance that are rapidly becoming untreatable.
The course will give insights about the global response to AMR, various initiatives put forth by stake holders and the role healthcare professionals can play to control AMR.
Three common clinical syndromes – respiratory infections, urinary tract infections and sepsis will be examined for which the clinical presentation is non- specific and antibiotics are often prescribed presumptively.
It will talk about bacterias that cause healthcare associated infections (HAIs) which will includes Methicillin- resistant Staphylococcus aureus (MRSA), Carbapenemase producing organisms (CPO), Clostridioides di cile (C diff) and Vancomycin-resistant enterococci (VRE)
Healthcare professionals will have a greater awareness of AMR and how it is caused during the online training programme through articles, mini-lectures and interviews with experts in the field to highlight some of the key issues and thinking around the role of diagnostics in response to AMR.
Besides, the training will also include a number of case studies, educational videos, animations and also assess learning through quizzes. This will also involve sharing experiences and views through discussion with fellow learners and the course team besides the reference lists and supplementary reading that can be useful during the study.
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Itchy Skin Conditions And Mental Health Are Linked, And We Need to Talk About It
Why do we itch? The reasons are many and varied. But what's becoming ever clearer is many who experience chronic itching due to skin conditions also shoulder a profound psychological burden no scratching can relieve.
While the nature of this link around conditions like eczema and psoriasis has been investigated before, scientists say we're still only beginning to understand how skin disorders, mental health problems, and quality of life all intersect.
"There are already studies showing evidence of a correlation between itch and mental health problems in general, and in specific skin disorders, but there is a lack of a cross-sectional study across chronic skin diseases," says dermatologist Florence J. Dalgard from Lund University in Sweden.
To help fill that gap, Dalgard and her team analysed data collected from thousands of dermatology patients with skin issues in 13 European countries, including the UK, France, Germany, Russia, and elsewhere.
In total, over 3,500 patients with varying skin diseases took part in the study, undergoing physical examinations and filling out a questionnaire which asked questions about their socio-economic background and experiences with itching, while also measuring symptoms of depression, anxiety, and suicidal ideation.
More than 1,300 people without skin conditions acted as a control group, self-reporting the same information.
When the research team analysed the responses, they found a number of associations between skin conditions, itching, mood disorders, and quality of life impairments.
In patients with skin conditions who reported itching, the prevalence of depression was 14.1 percent. This lowered to 5.7 percent in patients who didn't itch.
Controls without skin disorders who reported itching also had around a 6 percent prevalent of depression – while only 3.2 percent in the control group members who didn't have itching reported depression.
Anxiety bore a similar pattern, showing up in 21.4 percent of the patients with skin conditions and itching, and dropping to 12.3 percent in patients without itching, while approximately 8 percent of the controls reported anxiety.
The prevalence of suicidal ideation was higher in patients with itch (15.7 percent) than in patients without itch (9.1 percent); similarly, it was higher in controls with itch (18.6 percent) than controls without (8.6 percent).
Patients with itch further reported experiencing more negative life events than the patients without itch did (38.2 percent compared to 32.4 percent respectively), and the patients who experienced itching were also likely to experience more economic problems.
While the team acknowledge their data can prove nothing about causation one way or the other (and submit that mental health suffering could potentially induce itch to some degree), they suggest it is much more likely that skin diseases are the cause of itching, which then leads to mental health effects.
"Speculative reasons for this correlation is that itch correlates with skin inflammation and skin inflammation induces serotonin network in the brain leading to depression and anxiety," the authors write in their paper.
While more research is needed to explore the hypothesis, for now at least, the link between itching and depression looks more firmly established than ever.
And that, the researchers say, should be reflected in how we treat patients with skin conditions – with a multidisciplinary team of physicians to help support these people, and everything they may be dealing with.
At the same time, preventative programs might be able to play a role in helping to ease itching and maybe reducing the development of the serious psychological symptoms that appear to stem from it.
"Our findings demonstrate that the presence of itch in dermatological patients is significantly associated with clinical depression, suicidal ideation and stress," the researchers conclude.
"The study reveals that itch contributes substantially to the psychological burden of dermatological patients and confirms the multi-dimensional suffering of dermatological patients with itch."
The findings are reported in Journal of Investigative Dermatology.
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ICMR rolls out ICMR-DHR international fellowship programmes to augment capacity of Indian scientists
In order to augment capacity of Indian scientists in emerging areas of clinical, medicine and health sciences, Indian Council of Medical Research (ICMR) has rolled out ICMR-DHR (Department of Health Research) international fellowship programme to create a pool of talented health research personnel by facilitating advanced training to the latest advancements in knowledge through interaction with the international scientists.
DHR-ICMR fellowship programme aims to provide advanced training in India and abroad to medical and health research personnel in cutting edge research areas related to medicine and health.
It covers 25 fellowships per year for short term international fellowships for senior Indian biomedical scientists for a duration of two weeks to 3 months. The age limit is below 57 years as on last date of receipt of application.
It also covers 40 long term international fellowships for young Indian biomedical scientists for a duration of of 6 to 12 months. The age limit for the same is below 45 years as on last date of receipt of application. Applications should be submitted online through the website portal of ICMR/DHR at http://www.icmr.nic.in: http://www.dhr.gov.in.
Details of the eligibility, format of application, terms and conditions and guidelines of the programme are available on ICMR and DHR websites. Last date of receipt of applications is December 15, 2019.
Department of Health Research (DHR) under the union health ministry is entrusted with the promotion and co-ordination of basic, applied and clinical research including clinical trials and operational research in areas related to medical, health, biomedical and medical profession and education through development of infrastructure, manpower and skills in cutting edge areas and management of related information thereto.
It is also mandated to promote and provide guidance on research governance issues, including ethical issues in medical and health research.
DHR also covers inter-sectoral coordination and promotion of public-private partnership in medical, bio-medical and health research related areas, advanced training in research areas concerning medicine and health including grant of fellowships for such training in India and abroad, international cooperation in medical and health research including work related to international conferences in related areas in India and abroad.
It also gives technical support for dealing with epidemics and natural calamities.
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FDA Has Fast-Tracked a Long-Awaited Cystic Fibrosis Drug That May Help 90% of Patients
A new cystic fibrosis therapy dramatically improved patients' lung function and showed clear signs of targeting the genetic root of the disease, instead of just alleviating symptoms — a breakthrough so long-sought that many doctors and patients are moved to tears when talking about it.
The data, being unveiled Thursday at a national conference in Tennessee and simultaneously published in two leading medical journals, was so persuasive that the Food and Drug Administration last week approved the three-drug combination, called Trikafta — five months ahead of the agency's deadline.
The drug could benefit 90 percent of patients with the disease, a major advance over previous drugs that worked in a tiny fraction of the people with the disease or had more modest effects.
"I'm overjoyed," said Francis Collins, the director of the National Institutes of Health, who was part of one of the teams that in 1989 discovered the gene defect that causes cystic fibrosis.
"Thirty years along, with many bumps along the road and so many people waiting and hoping that something like this would happen — and here we are."
The drug is the product of decades of steady, incremental scientific work that began with research in academic laboratories and was pushed forward and funded by patient advocates through an unusual "venture philanthropy" model now being emulated by other patient groups.
The leap forward was preceded by many steps — Trikafta is the fourth therapy developed by Vertex Pharmaceuticals, a Boston-based company that has built a lucrative franchise around the disease.
Cystic fibrosis affects an estimated 30,000 people in the United States. Thick mucus builds up in the body's organs, damaging people's lungs and digestive systems.
Patients wear vibrating vests to break up the mucus and spend hours each day coughing to keep their lungs clear. They assiduously protect themselves from respiratory illnesses that can send them to the hospital.
They often take antibiotics, enzymes and vitamins to stay healthy. The life expectancy of patients has been increasing, and patients born today live on average 44 years.
Doctors who began their careers at a time when there were few adults with cystic fibrosis because patients died in their teens are now cautiously anticipating that the disease will be transformed into a chronic condition, akin to diabetes, that can be managed with a drug regimen — particularly if Trikafta is eventually approved for use in younger children and babies, before any lung damage has occurred. (It is initially approved for patients 12 and older.)
Patients who were unsure about whether they should bother attending college because they had always known they would die young are now being told they should think about planning for retirement.
Brian P. O'Sullivan, a pediatric pulmonologist at the Geisel School of Medicine at Dartmouth, who was not involved in either trial and has no financial ties to Vertex, said: "I'm in my 60s now, and I never thought I would see this day. It's pretty amazing."
Sarah Carollo, 28, a special needs teacher in Lee's Summit, Mo., started Trikafta through a clinical trial in late 2018. Carollo feared she was heading into yet another hospitalization and might have to step away from the classroom where she teaches children with nonverbal autism. She couldn't walk down a hallway without stopping to rest and catch her breath.
"As a person living with CF, my parents had been passing on to me this fear — we always had this constant fear of when the decline was going to happen, because we knew it was going to happen," Carollo said.
A few days after she began taking the pill, her doctors tested her lung function and were so stunned at the improvement that they had to check whether they were really looking at the results from the right patient. Earlier this month, Carollo ran a 5K race with another patient, Laurana Blackburn, who was also taking the drug through the clinical trial.
"We felt like we had to honor what we had been given and show the capacity of what we had now," Carollo said.
Cystic fibrosis has become a model for how to study, advocate for and develop drugs for other genetic diseases. The discovery of the gene in 1989 was a major scientific feat that helped persuade scientists and politicians to move forward with the $3 billion human genome project, Collins recalled. But that wasn't just important to scientists.
On Aug. 25, 1989, an 8-year-old girl named Jenny wrote in her diary, "To Day is the most Best day ever in my Life They found a Jean for Cistik fibrosis." Jenny McGlincy, now 38, was on vacation with her husband and daughter in Mexico when word began to circulate that the drug had been approved. She read the news on her phone and began crying.
McGlincy said she feels fortunate that she hasn't been as sick as other people with cystic fibrosis, but she is eagerly awaiting the doctor's appointment in a week and a half where she will find out the next steps to get access to the medication.
"We've finally reached the time that an improvement is possible," McGlincy said.
"To think of my lung function improving or my digestion increasing, or even adding a few years to my life that I could spend with my daughter. … Now that it's available, I'm a little like, 'Is this really happening?' "
The therapy is a combination of three drugs that wouldn't have been possible if scientists working in academic laboratories hadn't unraveled the basic biology of the disease. Finding the gene was a needle-in-a-haystack-type problem, Collins said, and it led scientists to a malfunctioning protein that normally keeps the right balance of salt and water in the lungs.
There are more than 1,700 gene mutations that can cause the protein to malfunction, but in the most common mutation, the protein is misfolded and can't reach the right spot in the cell — and even if it does reach that spot, it doesn't work properly. The new combination therapy includes one drug that corrects the misfolded protein and two that activate the correctly folded protein when it reaches the right spot in the cell.
In the largest trial, reported in the New England Journal of Medicine, 403 patients who had at least one copy of the most common gene mutation underlying cystic fibrosis received either Trikafta or a placebo. There were improvements in objective tests of lung function, decreases in lung problems and hospitalizations and an increase in people's quality of life.
Many physicians see the most transformative potential impact of the drug in the hope that it will be eventually approved for younger children, as Vertex's other drugs have been over time.
The drug can help older patients, but it can't erase years of lung damage; if it works and is safe in younger children, it could prevent damage in the first place.
"With treatments like this, we can actually anticipate that if a young child were started on this therapy, they could actually expect to have a normal life expectancy," said Deepika Polineni, a pulmonologist at the University of Kansas Medical Center involved in the trial who has received consulting fees from Vertex.
"This is a breakthrough therapy for people with cystic fibrosis."
Patients continued their maintenance therapy, such as coughing and using a vibrating vest, during the therapy — and future trials will test whether patients can reduce their dependence on the time-consuming regimen. Future research will also be needed to help the remaining 10 percent of patients, who have different gene mutations causing their disease.
Meghan McGarry, a pulmonologist at the University of California at San Francisco, recently completed a study that examined Puerto Rican and Dominican patients and found that their diseases were driven by rare mutations.
She said her concern is that the new drugs, as exciting as they are, will deepen health inequities, because those minority patients already have greater mortality than white patients with cystic fibrosis.
"It's really heartbreaking for the patients who don't qualify. I think it's really hard to celebrate with a portion of your patients and have other patients where you know they don't have that. We had a mom who said, 'Those drugs aren't for our people,'" McGarry said.
She noted that when some of Vertex's early drugs came out and helped a small population of patients, it gave others in the community hope because it foreshadowed the development of better drugs that would work for more people.
"Now, when the majority of patients already have it," she said, they ask: "When is it my child's turn? And is that going to come?"
It also remains to be seen whether patients have an easy time gaining access to the drug, which will cost $311,000 a year. While that is a tremendous amount, orphan drugs for small patient populations typically carry very large price tags, and physicians are optimistic that insurers will cover the drug.
For now, the cystic fibrosis community will be celebrating. Collins said that after he discovered the gene behind the illness in 1989, he wrote a song called "Dare to Dream" about the hope for a treatment. He plans to sing it at the meeting.
When he wrote the song, "we had the gene, but it wasn't clear how it would get us to this kind of outcome," Collins said. "We're going to do that again on Friday morning, with 3,000 people, and I'm probably going to cry."
2019 © The Washington Post
This article was originally published by The Washington Post.
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subset: commoncrawl


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Map images and Graphs of Southern California for a research Paper for Design Today
Budget $30-250 USD
We're looking to make map images our Southern California for a research paper.
Image 5
Layered on top of it, we'd like circles representing the major work centers in the city, like this (the blue-ish cloud in the background…the darker the blue, the more concentrated the jobs):
Image 6
The second image is pretty similar to something we're looking for – this image is representing metro lines though, and not traffic.
Also, we'd like an image similar to this one for just LA, but a little more modern looking (not so box-ey). It should represent populations across LA county.
And lastly, can you re-create these graphs, but also more modern/slick looking.
Budget is $15-40 for completed good and approved image.
We would like to work on these images today.
30 freelancere byder i gennemsnit $60 på dette job
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- Maan Café
- Name in Chinese :漫咖啡
- Telephone:+86 571 89700377
- Address:No. 6 Building of Queen Park, No. 227, Wulin Road
Just off Wulin Road is Maan Café. It's a Korean Café with floor-to-ceiling windows, making it very bright and spacious. Maan's coffee is a little different, more like beverage. However, its waffles are superb. The fruit waffle has a nice mix of ice creams served alongside and is delightfully crunchy on the outside and fluffy inside; definitely a must-get. Waffles cost around 70RMB and sandwiches around 50RMB, while coffees hover around the 30RMB mark.
What's worth mentioning is that once you order, they give you a teddy bear, and that's how they magically identify you at your table when they bring out your order.
Nearby Sights
China boasts as many as thirty-six West Lakes, but the one in Hangzhou is the most magnificent with exceptional natural beauty. As the old saying goes, " Of the thirty-six West Lakes east or west,...
The silk market is an old-time favorite when looking for small gifts or fabric. They have an impressive range of quality and taste, and it's all nicely priced. The cluster of shops makes it...


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Yeah, there was something else but how do you say that over the phone with all kinds of people around who may not be listening in but I feel like they would be and then they would be judging me and silently be calling me names in their heads.
God, sometimes it sucks to be a woman and having the assumption thrust upon you that you must be a slut. Even without mentioning a single word of sex, people jump to a conclusion based on appearances, personality, who you talk to, if you go out drinking and of course (the real kicker) just because you're female.
"Cecelia?" Jai asked nervously. "Are you still there?"
"Yeah, sorry, just went off into my own little world there."
"Okay, I'll see you soon."
"Okay, bye."
I'd just missed the opportunity to tell him that I wanted him, preferably naked, feeding me cake. Cheesecake would have been a top choice but followed quickly by cinnamon tea cake, chocolate cake with genash icing dripping down the sides, and then vanilla cake with a classic butter cream icing. If only I had said "Put pants on and bring cake"... or no cake.
For me to say no cake, just him, is almost heresy.
Twenty minutes later I was still obsessing over the words I hadn't said to Jai when he appeared in the doorway.
Yep, him naked, cake or no cake, would be amazing. He hadn't spotted me yet and I took the chance of watching him, not in a creepy way of stalking, just seeing who he was when not flirting or sure footed.
He was swivelling his head left and right, looking over the heads of most of the people out back. He didn't look sure of himself. Actually he looked awkward and a little afraid. Of what? Being stood up and having people around him think he was an idiot? Possible.
Frowning he pulled out his phone.
Mine began to vibrate and ring. Quickly I held it up to my ear. "Hey Jai."
"Hey, I'm here, where are you?"
Was it just my imagination or did that sound a little too forced to be relaxed? As if he was putting on a mask to hide the fact he was uncomfortable?
I smiled and stepped out from the wall where I had been insulated by the bodies of smokers and waved my arm in the air, not caring anymore if people thought I was acting like an idiot. "Right in front of you."
His eyes latched onto me and the frown disappeared. "What are you doing?"
"Getting your attention. Is it working?"
"Hmm, there are other ways you could get my attention." He whispered into my ear.
I raised an eye brow. "Do you mean like this?" I dropped my hand down to sit on my hip which bounced up. With my mobile still in hand I thrust it into the mass of my hair, making it even more messy, and pouted my lips and batted my eye lashes.
Jai dropped open his jaw and stumbled forward.
I laughed.
He snapped shut his mouth and grinned as he walked over. "Very nice."
I slipped my phone back into my bag and shook my hair out. "Thank you. Glad you appreciated it."
Hesitantly he reached out his hand and touched my hair, picking up a chunk and slipping it back behind my ear. "You have made one big mess of this."
"You should see it in the morning when I roll out of bed." I could feel the tip of my ear burning hot.
"Hmm, should I?"
"It is out to here," using my hands I measured out past my shoulders.
"Do you really toss and turn that much in bed?"
I would be an idiot if I wasn't picking up on where this conversation was leading or what was the real meaning behind our words. But that didn't mean I was going to just come out and say, hey you can find out tomorrow morning. No, instead I went with, "Not really, my hair just frizzes a lot."
He looked confused. "Right."
Tehehe, this was fun. "So what were you doing before I rudely interrupted you and dragged you out."
Jai ducked his head. "I was in bed and I'll let your imagination fill in the blanks."
"Don't trust my imagination."
"Why not? It's probably spot on."
Most likely, especially going off the red flush covering his cheeks. Had he really been masturbating? "I'm going to assume you were contemplating the big questions in life."
He chuckled. "Nope."
"Counting sheep?"
"Nah." He frowned, as if he wasn't sure where I was leading him. "Not even close."
"Well, were you dressed?"
Oh my, that was an image I really didn't want to lose from my mind. "So what is it that you can do naked while lying down? And in bed no less."
"I'm not sure I want to tell you anymore."
"Well, I probably wouldn't believe you. Not without some sort of proof."
"And just how do go about proving that I was..."
"Yes?" I encouraged. "Playing with your joy stick?"
"What?" he laughed and looked at me like I was crazy. "Is that what you call it?"
I shrugged. "What else do you call a controller for a video game?"
"Huh? I wasn't playing... we're not talking about the same thing are we?"
"Maybe. Probably."
"I'm missing something."
I couldn't stop giggling. He had been playing with himself when I called. Does that mean he was still touching while talking to me or had he pulled the sheet over and focussed on our conversation? "Nah, I think I know what you were doing."
"And what was that?"


text:
Filmfest 2019
Denmark, Sweden 2011
Original version with English subtitles
(Original: English, French, Danish)
Director: Mads Brügger
Section: Retrospective | Mads Brügger
For 135,000 dollars, Mads Brügger buys an African diplomatic passport in this satirical documentary. Posing as an honorary consul from Liberia, he wants to enter the trade in blood diamonds in the Central African Republic. After several meetings with corrupt politicians, foreign legionnaires, and shadowy hoodlums, it all becomes clear: without lots of bribes, nothing gets done in this place that's overrun with heavily armed rebels and violent gangs. Brügger, who has made himself into a caricature of a 19th-century colonialist, won't end his life-threatening cinematic experiment even after one of his interviewees is murdered.
With: Mads Brügger, Heather Schmid
Screenplay: Mads Brügger, Maja Jul Larsen
Director of Photography: Johan Stahl Winthereik
Film Editor: Leif Axel Kjeldsen, Carsten Søsted, Kimmo Taavila
Composer: Niklas Schak, Tin Soheili
Producer: Peter Engel, Carsten Holst
Co-Producer: Tomas Eskilsson
Production Company: Globus
Director: Mads Brügger


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As a data and analytics company, Divvit takes pride in taking every measure so that our merchants' data is as secure and private as it can be.
With the GDPR, we feel it's our duty to inform you of how we're staying compliant and just what we're doing to protect your data.
How we've prepared:
The good news is that we've built our company with the GDPR in mind. The GDPR was approved by the EU on April 14, 2016, before we were open to the public. From our first Terms and Conditions and Data Privacy agreements, we have taken the GDPR into account.
We have been in close contact with our Data Privacy advisor, who has reviewed our company from a Data Privacy perspective and have teamed up with a legal team to make sure that we were compliant at every step of the way.
Divvit's Roles within the GDPR
Divvit falls into two unique categories under the GDPR when it comes to Data Privacy.
- Data Controller: for the personal data collected from our direct users (merchants)
- Data Processor: for the personal data from the visitors of our users (our merchants' customers)
As the Data Controller for our merchants, we hold to the following responsibilities and offer our users:
- Collecting Consent: We are completely clear and transparent about how we use the data that we collect from our users when we ask for consent. We have chosen to comply with the GDPR by requiring an active opt-in to our Terms and Conditions and Data Privacy Processing, with a link to these aforementioned documents.
- Right to Access: Our users are able to access the processed data that we have collected on them at any time upon request. Simply contacting us at email@example.com is enough to get access to this data.
- Right to Rectification: Our users have the right to correct any inaccurate personal data concerning them, or completing incomplete data. Our users can notify us of any inaccurate personal data at email@example.com at any time, and we will correct it without delay.
- Right to Erasure: Our users have the right to be forgotten, and we are obliged to erase any personal data on our user upon request at email@example.com, or when the data is no longer relevant to the original purposes for processing.
- Right to Data Portability: Our users have the right to obtain the data concerning them in "commonly used and machine readable format" and the right to transmit that data to another controller. Requests for this can be made at email@example.com.
As a Data Processor for the visitors and customers of our users, we have different responsibilities. Our users become the Data Controllers, and we function as Data Processor.
This ultimately means that our users are responsible for the responsibilities of their visitors as Data Controllers. The distinction between our roles to our users and our roles to our users' visitors is important, as the GDPR considers the Data Controller as the primary responsibility of compliance with users.
This means that if consent is revoked for one of your customers or visitors, it is your responsibility to comply with erasing, rectifying, and providing that data to your users. It also means that you need to notify us, as your Data Processor, so that we can remove the data from our servers.
Our responsibilities as Data Processor include:
- We can only process personal data on the instructions from the Data Controller (our users) and inform the Data Controller if we believe that these instructions infringe on the GDPR.
- We need written permission from the controller before engaging a subcontractor.
- We will delete or return all personal data to the controller at the end of the service contract upon request at email@example.com.
- We will enable and contribute to compliance audits by the controller or representative of the controller.
- We take reasonable steps to secure data, such as encryption and pseudonymization, stability and uptime, backup and disaster recovery, with regular security testing.
- We will notify Data Controllers without delay upon learning of data breaches.
- We will restrict personal data transfer to a third country or international organization unless the controller has provided appropriate safeguards
What we do with the data we process:
The purpose of the data that we collect and process is crucial for GDPR compliance. We have defined our purpose as:
"To enable the features of our service as described in the applicable Service Descriptions, including but not limited to:
- Enabling tracking of our user's customer from his or her first visit on the user's webpage until the first purchase is made, including tracking of information about the products bought, etc.
- Enabling monitoring of our users' customers' lifetime value, the number of purchases made, etc.
- Enabling identification of our users' customers across multiple devices.
- Enabling segmentation of our users' customers, for example "large customers" or "one time customer."
- Enabling the use of above segmentation when communicating with the customers via email, customized ads, or directly on the user's webpage.
What kind of data we collect:
All of the data that we collect is integral to providing our services to our users, and we want to be transparent about exactly what we collect, when, and why.
When it comes to the data about page views of our user's visitors, we collect the following data:
- IP address
- Current URL
- Referrer URL
- Timestamp
- User ID Cookie
- User-agent
- Page load time
- Orders
When it comes to the orders of our users, we collect the following data:
- Products
- Price
- Discount
- Shipping
- Customer name
- Customer ID
- Payment method
When it comes to data about the users' visitors' carts, we collect the following data:
- Added and removed products, and their prices
Concerning data privacy and security, Divvit has always been over compliant because we take data seriously. From the time we started our company, privacy and security has been a top priority in everything we've done.
We will continue to protect our users' data in every way we know how, and any questions about this article, our Privacy Policy, and/or our Terms and Conditions, can be directed to firstname.lastname@example.com.


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Slack creates alignment and shared understanding across your team, making you extra productive, less confused, and just a bit bit happier. The day just received better." Or: At all times get plenty of sleep, if you can." (They're all signed from your mates at Slack.") The left aspect of the display screen lists your contacts and group channels," with inexperienced lights to point whether or not users are lively and pink badges to mark unread messages.
Tech and media companies have been maybe the quickest and most ardent in their embrace, which also means their workers are furthest alongside the trail to Slack-jadedness. Along with the AWS companies, Slack is using the Redis knowledge structure server, the Apache Solr search device, the Squid caching proxy, and a MySQL database.
Actual-time chat relies on one-line-at-a-time messages, which discourages full, considerate conversations. The corporate's cloud-internet hosting unit, Amazon Net Services, in February unveiled a paid-for video and audio conferencing service – Amazon Chime – that lets customers chat and share content material.
Though he is making on-line communication sooner, Stewart Butterfield, co-founder and CEO of Slack, still believes in face time along with his group, proven right here on the company's San Francisco headquarters. Inner social tools might help workers make faster selections, develop extra revolutionary ideas for services, and develop into more engaged in their work and their companies.
Channels are generally dedicated to hobbies or snacks, however the general thought is to improve office collaboration and communication. As a member of Slack's beta neighborhood, you will robotically receive new builds of the Slack app before they turn into obtainable to the public.


text:
South Brooklyn Railway
Coordinates: 40°39′16″N 74°00′36″W / 40.6545436°N 74.0099555°W
This article needs additional citations for verification. (October 2016) (Learn how and when to remove this template message)
|South Brooklyn Railway
South Brooklyn Railway junction, under Exit 23 of the Gowanus Expressway
|Freight rail
|None; connected to New York City Subway
|Sunset Park, Brooklyn, New York City
|South Brooklyn Marine Terminal (west)
36th–38th Street Yard (east)
|City of New York
|New York City Transit Authority
|Freight railroad
|Rolling stock
|2 GE47T diesels
|Track gauge
|4 ft 8 1⁄2 in (1,435 mm) standard gauge
The South Brooklyn Railway (reporting mark SBK) is a railroad in the New York City borough of Brooklyn. It is owned by the City of New York and operated by the New York City Transit Authority. Its original main line ran parallel to 38th Street from the Upper New York Bay to McDonald Avenue, and south on McDonald Avenue to the Coney Island Yards, mostly underneath the former Culver Shuttle and the IND Culver Line of the New York City Subway.
Parts of the original line still exist. The section between the BMT West End Line's Ninth Avenue station and its interchange yard at Second Avenue and 39th Street is still open. The section under the IND Culver Line has been paved over. Today, it runs only from the 36th–38th Street Yard in the east to the South Brooklyn Marine Terminal in the west.
Private operationEdit
The South Brooklyn Railroad and Terminal Company was incorporated September 30, 1887 to build from the end of the Brooklyn, Bath and West End Railroad (West End Line) at 38th Street and 9th Avenue northwest to the foot of 38th Street, and was leased to the BB&WE, allowing BB&WE trains to run to the 39th Street Ferry.[1] The land purchases were completed in 1892, and the South Brooklyn Railway & Terminal Company built a terminal station and freight house at Third Avenue.[2] The company was not a "railroad" in the strictest sense, as it did not own any rail vehicles, but instead owned several city blocks to lease to other railroads that wished to connect to the ferry terminal at 39th Street.[2]
The Prospect Park and South Brooklyn Railroad connected the Prospect Park and Coney Island Railroad (Culver Line) to the South Brooklyn Railroad in 1890, and the latter was bought by the Long Island Rail Road in 1893. The LIRR obtained the South Brooklyn Railway & Terminal Company lease on the land in 1897 and used steam powered locomotives.[2] As these locomotives could not be used for freight operations, the line was electrified in 1899; however, the LIRR occasionally ran steam-powered special trains to the Brooklyn Jockey Club Racetrack at Kings Highway and Ocean Parkway.[2] After foreclosure of the South Brooklyn Railroad & Terminal Company in December 1899, the company was reorganized as the South Brooklyn Railway on January 13, 1900.[2][3]
The Brooklyn Rapid Transit Company acquired the railway on August 31, 1902,[3] but the LIRR still ran the trains until 1903 or 1905.[2] After the cessation of LIRR operations, the BRT started passenger service and transferred freight service to a subsidiary, Brooklyn Heights Railroad, which provided freight service with three locomotives, with a fourth delivered in 1907. It carried mail for the U.S. Post Office Department, as well as lumber, cement, sand, stone, ashes, pipe, marble for headstones, and granite for curbstones.[2]
At its greatest extent, the line ran along Second Avenue, then merged with the BMT West End Line from Fourth Avenue to the Ninth Avenue station. From there, it ran at street level under the BMT Culver Line down McDonald Avenue to Avenue X.[4]
On February 28, 1907, the South Brooklyn Railway and the Brooklyn Heights Railroad were split from each other, but both were still owned by the BRT. The South Brooklyn Railway was a separate subsidiary company that carried both passengers and freight, to avoid the BRT from being operated under Interstate Commerce Commission regulations. The Brooklyn Heights Railroad leased the Prospect Park and Coney Island Railroad, which included the Prospect Park and South Brooklyn Railroad, giving it a line to Coney Island.[2]
In 1909, the South Brooklyn Railway was granted a request by the Public Services Commission to discontinue the use of the Third Avenue freight yard and station, on the Prospect Park and Coney Island Railroad's property. The freight house, which was leased from the LIRR, was deteriorating, and the South Brooklyn Railway did not want to build a new one on LIRR property, instead preferring to build a replacement on the property of the New York and Sea Beach Railroad, using Sea Beach trackage to access the new terminal. The South Brooklyn Railway bought another locomotive.[2] In 1913, all of the BRT's lines were reorganized, and all ownership of freight operations was transferred to the South Brooklyn Railway.[2]
The location of the South Brooklyn Railway helped in the construction of new BRT subway and elevated lines in Brooklyn, as materials could be brought in via its trackage. A temporary connection at 38th Street and Fourth Avenue allowed South Brooklyn Railway equipment to enter the BMT Fourth Avenue Line construction site.[2] In June 1922, the South Brooklyn Railway bought much of the LIRR-owned Prospect Park & Coney Island Railroad. By 1923, the Prospect Park & Coney Island Railroad and the New York & Coney Island Railroad were merged into the South Brooklyn Railway. The BRT filed bankruptcy that year and was reorganized into the Brooklyn–Manhattan Transit Corporation, which still operated the South Brooklyn Railway.[2]
City operationEdit
The South Brooklyn Railway, along with the other non-rapid transit properties of the BMT, was transferred to the New York City Board of Transportation on June 1, 1940.[5] That year, freight traffic went up significantly due to the start of World War II. The South Brooklyn Railway also got some trucks to deliver incoming freight directly to customers. In 1946, after the war, South Brooklyn Railway purchased two Whitcomb ex-U.S. Army diesel locomotives.[2]
Operations were transferred to the New York City Transit Authority on June 15, 1953.[6] Passenger service on McDonald Avenue ended on October 31, 1958, and thereafter the South Brooklyn Railway started using the surface trackage solely for freight.[2] In 1960, two more diesel electric locomotives were bought. On December 27, 1961, the line was de-electrified, due to the high cost of refurbishing the overhead trolley wire. Electric locomotives #4, 5, 6, and 7, which had third rail conduction shoes, were given to the NYCTA for subway and elevated operation.[2]
The switches at Kensington Junction were locked so that the branch was completely separated up to the Ninth Avenue & 20th Street Depot, which thereby became an unneeded facility because passenger streetcar operation had ended. At the same time, freight usage of the South Brooklyn Railway declined because of the increasing use of semi-trailer trucks. The McDonald Avenue trackage was no longer in use by 1978, and paved over by 1991.[2] After the closure of the McDonald Avenue tracks, the South Brooklyn Railway's freight operations were moved from the Second Avenue yard to the 36th–38th Street Yard, where it still operates.[4] In 1994, the last non-NYCTA customer on the line closed; the South Brooklyn Railway was then used almost exclusively for subway connections to the LIRR Bay Ridge Branch via the South Brooklyn Marine Terminal, Bush Terminal, and Industry City.[2]
Current statusEdit
The South Brooklyn Railway provides one of only two track connections between the New York City Subway and the rest of the American rail network. During the 1988 and 1999 reconstruction of the subway tracks on the Williamsburg Bridge, this connection allowed trains from the J/Z, L and M services, which were otherwise isolated during that period, to travel to Coney Island Yard for major work. At the other mainline rail connection at the Linden Shops, subway trains traveled via the Bay Ridge Branch of the Long Island Rail Road to the Brooklyn Army Terminal. From there, the at-grade New York Cross Harbor Railroad brought the cars up to the interchange yard at Second Avenue, where the South Brooklyn Railway took them to Coney Island Yard via the BMT West End Line.[4][7]
The South Brooklyn Railway has two locomotives, N1 and N2, a pair of GE 47T Diesels. They can also be used on the subway when not needed for the SBK.[2]
A refurbishment of the interchange with New York New Jersey Rail, LLC at the South Brooklyn Marine Terminal Second Avenue Yard was completed in May 2012. A new ramp was installed at the 38th Street Yard at Fourth Avenue to allow receipt of new R156 locomotives and other subway rolling stock that were delivered on flat cars.[8]
- ^ "SBRT information". Retrieved October 5, 2016.
- ^ a b c d e f g h i j k l m n o p q r "South Brooklyn Railway". trainweb.org.
- ^ a b State of New York Transit Commission: First Annual Report (April 21, 1921-December 31, 1921). J.B. Lyon Company. January 9, 1922. Retrieved 25 July 2016.
- ^ a b c "I COVER THE WATERFRONT. Brooklyn's waterfront railroads". forgotten-ny.com.
- ^ "PRR Chronology, 1940" (PDF). (35.3 KiB), August 2004 Edition
- ^ "PRR Chronology, 1953" (PDF). (48.7 KiB), December 2004 Edition
- ^ Cross Harbor oldnyc.com
- ^ "South Brooklyn Railway". trainweb.com.
External linksEdit
- South Brooklyn Railway Industrial, Offline Terminal Railroads and Rail-Marine Operations of Brooklyn, Queens, Staten Island, Bronx & Manhattan
- Cross Harbor oldnyc.com
- Brooklyn's waterfront railroads at Forgotten NY
- Arrt's Arrchives: South Brooklyn Railway


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Icon for Hire at Moroccan Lounge
with Cosmo, ejaaz on 08/13/2019
Icon For Hire is a rock band formed in 2007 from Decatur, Illinois. The current lineup consists of frontwoman, vocalist Ariel Bloomer, better known as Ariel alone and guitarist Shawn Jump. Icon For Hire has released three full length albums: Scripted, Icon For Hire and YOU CAN'T KILL US. Released in 2011, their first album Scripted shattered first-week sales becoming the highest new artist debut in Tooth & Nail Records history. The record debuted on the Billboard Top 200, at No. Read more on Last.fm
Band info and image from Last.fm. Concerts by Songkick. Tickets may be available at Songkick.com


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Lindsay Lohan did some promotion for her new MTV series, Lohan Beach Club, last month. I was critical of her, because I know in my heart that Lindsay Lohan is still the cracked-out narcissist who would gladly and gleefully mow down a dozen pedestrians to get an inch of fame. Some commenters suggested that I should be nicer to Lindsay in this post-MeToo era, because many are convinced that Lindsay has been victimized too. I never said she wasn't a victim – she had sh-tty parents, she's been mistreated and abused by men, I'm sure. … ...Read full story
Paris Hilton Clarifies Her 'Pathological Liar' Comment About Lindsay Lohan – Watch!
Paris Hilton is reacting a recent comment she made in reference to Lindsay Lohan. After making the comment on Instagram days ago in response to a video of Lindsay from years ago, Paris was asked about calling Lindsay a "pathological liar," and whether that was a joke. PHOTOS: Check out the latest pics of Paris Hilton "Just stating a fact," she explained, throwing her hand up. "Fact of life." She also addressed Lindsay's upcoming reality show: "Good luck to her. I wish her the best," Paris said. Watch her respond to ...Read full story
Lindsay Lohan Working on Reality Show Where She's the Boss
At long last, Lindsay Lohan will be back in our American lives. It's been years since Lohan has fully graced us with her presence. Sure, she did that lawyer commercial, but that was nothing more than a cocktease. Now, we could be getting the real thing. In a New York Times profile piece, Lohan mentions working with MTV to develop a reality show centering around her and the opening of the Lohan Beach House in the Greek island of Rhodes. The show will be akin to Vanderpump Rules and feature cameras capturing the ins and outs of … ...Read full story
Lindsay Lohan Shows Off Her Street Style During Madrid Fashion Week
Lindsay Lohan was all smiles as she visited a Madrid theme park! The 31-year-old actress stopped by to ride some of the attractions on Monday (September 18) in Madrid, Spain. PHOTOS: Check out the latest pics of Lindsay Lohan Lindsay was taking a break from attending Madrid Fashion Week shows. She rocked a long denim coat over a white slip dress, yellow platform shoes, and oversized sunglasses. That same day, Lindsay checked out the presentation of the Jorge Vazquez … ...Read full story
"Lindsay Lohan is launching her own lifestyle site, lord help us" links
Come see what I'm really up to ?? https://t.co/wMhKaWpSIV pic.twitter.com/azpCu00l6j — Lindsay Lohan (@lindsaylohan) June 27, 2017 Lindsay Lohan is launching a lifestyle website. God help us all. [Dlisted] Johnny Depp hasn't lost any work following his "joke" last week. [LaineyGossip] Marisa Tomei's recent looks are cute. [Go Fug Yourself] Sarah Palin is suing the New York Times. [Pajiba] Donald … ...Read full story
Lindsay Lohan Clings to Last Shred of Dignity, Turns Down Burger King Commercial Spot
In a shocking twist of events, it turns out Lindsay Lohan does possess a low-level of standards; the "broke" (HAHAHHAHAHHA – JK SOBBING AT MY OWN FINANCES) star turned down starring in Burger King's latest ad campaign. Burger King propositioned Lohan to don a Spicy Chicken Fry box dress, smoke a chicken fry, and give a sppppicy monologue, but homegirl's got pride! Yes, she's already spent years mocking herself including her hosting SNL, but this is "making fun of her issues!" Because the world wasn't already doing that without your help, Lindsboi! Lohan and her managers at Untitled Talent (you think they just forgot to delete… ...Read full story


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A French Wine With a 900-Year-Old Vintage
Once wine growers find a variety that works, the study reinforces, they'll stick with it for centuries, or even millenniums.
Savagnin blanc — not to be confused with the sauvignon blanc the sommelier recommended with your cheese course — is a fruity, acidic grape from the vine-encrusted hills of Jura, near France's border with Switzerland. And if you visit and sip the region's white wines today, you'll be tasting the exact same grape, down to the genetic level, that has gone into its wines for at least 900 years.
"It's kind of frozen in time," said Nathan Wales, an archaeologist at the University of York in the UK and the lead author of the paper, published Monday in the journal Nature Plants. "I had assumed that they were just recycling the names, and lineages would come and go, but we can see that's not the case."
[Like the Science Times page on Facebook. | Sign up for the Science Times newsletter.]
The study followed an analysis of the DNA of 28 grape seeds found in wells and latrines at various archaeological sites in France, where crushed wine grapes were dumped, or simply excreted by animals or people who ate them. Dr. Wales's team then compared those sequences to GrapeReSeq, a genetic bank for contemporary wine grapes.
Their findings reinforce how winemakers can devote centuries, if not millenniums, of loyalty to certain varieties of grapes. Faced with the choice of letting nature takes its course and allowing new grape varieties to develop, or sticking with a reliable fruit by grafting vines to create perfect clones, most growers have spent the last 10 or 20 centuries learning how to better produce what works.
The new DNA results are consistent with historical records, which had suggested viticulture in this region goes back at least 2,000 years. Back in the first century, when Roman vineyards dotted southern France, Pliny the Elder described 91 grape varieties. He also described the grafting technique still commonly used for cloning grapevines. But it hasn't been easy to link the Roman names he used to current vines.
Dr. Wales's team found continuity that might reach back to Pliny's age.
In La Madeleine, a church complex in the city of Orleans, a seed found in almost a thousand year-old cesspit turned to be an exact match for modern-day savagnin blanc.
Other seeds seemed to be separated from their contemporary relatives by only one reproductive cycle in almost two millenniums. One seed found in a first-century Roman well was closely related enough to have shared a parent with Pinot Noir grapes, for example. Three more seeds in a second-century pit were related in the same way to Syrah grapes.
In addition to quaffing wines very similar to modern-day Pinot and Syrah, the Romans also must have transported varieties they liked over large distances, as historians have long believed. The closest relative to one seed, found near the coast of southern France, is now grown solely in the Alps.
In the future, Dr. Wales says, looking into the lineages of even more ancient seeds could help breeding efforts. Plus it could help test how long local agricultural traditions really go back.
"It's pretty cool that when you lift a glass of savagnin blanc today, the genetic identity of the wine in your glass is identical to something that was being drunk so long ago," said Sean Myles at Dalhousie University in Canada, who led an earlier genetic study of over a thousand modern wine grapes but was not involved in the current study.
This past weekend, to celebrate the study's forthcoming publication, Dr. Wales bought a bottle of Gewürztraminer, a pink-hued savagnin blanc relative that was easier to get outside of France.
"It was delicious," he says.
Earlier reporting on ancient wine


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Last night I wrestled insulators onto our outdoor faucets with my stiff fingers and thought about winter. I struggle at this time of year. I never seem to click over to the scourge known as daylight savings time; I nod off early in the evening – even for me – then awaken in foul temper, a couple hours before the sun can be bothered to appear. Though, with the recent cold, there have been clear days – a sweet reprieve from our usual long, sodden darkness.
Besides the shivers, I have also had writer's block, but thankfully, not Eater's block. The season has provided opportunities to feast in fashions both lavish and restrained. Yes, you can feast with restraint; as I edge ever-nearer to the half century mark, enjoying a meal while keeping my corset laced yields more positive results.
The late fall began with a party at my sister's – a send-off for a beloved housemate and friend. I was charged with bringing cake. You won't be surprised to hear that I am similarly charged, with some regularity. I made an old favorite: chocolate ganache drenched vanilla cake filled with marzipan and apricot jam. I sound like I am showing off, but I hardly ever make this, and after all the labor, the results were underwhelming.
This cake has been an opiate of the masses in the past, but on this occasion, it was dense and gluey. This let-down inspired me to research a new white cake recipe. I was happy with the resulting amalgam of two Mark Bittman recipes, and decked it with roasted rhubarb frosting,* creating a pink sensation for my dad's birthday get-together with his siblings. You may notice the frosting is not completely emulsified, and I am open to advice about this. I am MaryCake, but my icings can be decidedly un-merry (still delicious though).
And then Thanksgiving came and I slaved, and shlepped, and…actually I did no such thing. I gave up on holiday martyrdom years ago. I did make fresh cranberry-pineapple salad, which remains as thrillingly zesty as when my mom first made her rendition, thirty years ago. I was in charge of stuffing, (it's theoretical stuffing, since we don't stuff our turkey) and I was working on the curd for our now traditional key lime pie, when my oldest took over and finished it. We used crushed meyer lemon cookies for the crust this time. My husband assumed responsibility for the turkey years ago and he does a perfect job. My oldest also made pumpkin biscuits, adorable pecan tarts, and mashed potatoes. Next year I will spend the holiday alone in Barbados – they don't need me!
At the risk of sounding like the Grinch who stole Thanksgiving, (Don't we all have some grudging admiration for that guy? Talk about a heist!) I don't actually like pumpkin pie anymore. Pie crusts are meant to contain berries and custards, not tubers and gourds – for me anyway. But our guests are always horrified at this, and will bring a pumpkin pie, rather than suffer through the meal without one waiting at the end with its confusing texture and odd color. We are now a BYOPP house. Unless you love baking pumpkin pie, try threatening your guests and family with its absence. Someone will rise to the occasion.
I don't want to miss the season; I want to be alive to every frosty sparkle, grateful for every ice-coated leaf. But then, as I told my husband, I also want to take part in a scientific study of human hibernation. I picture myself in a cave, snoring away in an ursine heap, looking like an enormous muppet in my green, fuzzy robe. Everyone would be terrified to disturb me for fear of my ensuing rotten mood and bared teeth.
Shhhhh. Nudge me when it's Spring.
*The frosting recipe comes from Yottam Ottelenghi and Helen Yoh's Sweet.


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My Approach to Helping
Life is stressful. Often we can get through difficulties on our own, if things are simple. However, life can be complicated and then we are suddenly overwhelmed by life and relationships. Sometimes there is just too much at once. Worry becomes a full time job. Energy is lacking. It is hard to stay focused. Everything becomes an uphill battle. You may be feeling irritable or getting angry over little things. Relationships become strained. Communication seems to make things worse! If you are experiencing these things, you are not alone. Therapy can help.
I work to help people learn practical skills so that life is more fulfilling and less of a struggle. Cognitive-Behavioral Therapy, or CBT, is one approach that can be very helpful in changing unhealthy thoughts and behaviors. We work together to identify thinking patterns, increase your control of your thinking, and improve your mood. In Couples Counseling, we will work on increasing healthy communication, decreasing conflict, working toward common goals. Counseling can help you start enjoying your life again!


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The future of employee assessments was a big trend at the Society of Industrial and Organizational Psychology (SIOP) annual conference in 2018. Artificial intelligence, virtual reality, automation...you name it, it was discussed. Many employers and assessment creators have an interest in how these "tools of the future" can further enhance the predictiveness of current selection systems, but much of this is still unknown as we have only just begun in these areas compared to other assessment methodologies.In one particular ignite session, panelists were asked to depict what the future of selection systems will look like. If you are not familiar with ignite sessions, presenters are tasked with presenting 20 slides each, each of which will automatically advance after 20 seconds. The panel was asked to focus on how artificial intelligence will make an impact on hiring processes in 2028. Thus, each panelist took the audience through a brief presentation of what they think employee selection systems will look like 10 years from now.
Below, we will take a look at what selection experts think will stay the same and what they feel will be much different.
What's Staying the Same:
- Competencies Important for Successful Job Performance
One consensus of the panelists was that behavioral competencies important for success in roles now will stay the same in the future. For example, being goal-oriented in 2018 will still be just as important in 2028 for success in sales roles. One panelist put forth the idea that the act of manual job analysis (e.g., job observations, plant tours, focus groups) will become obsolete by 2028, as technology will allow us to store historical job analysis data and through a series of algorithms, map that information to other or similar roles.Read more: Should Your Hiring Process Change for New Manufacturing Technology?
- Candidate Experience
How candidates perceive their experience through the hiring process, including their perceptions of the organization, was as area that panelists expressed as continuing to be important. One may argue that candidate experience will become even more important by 2028, especially if the tight labor market makes a return. Consensus was expressed around candidate experience as a key to shaping the employer of choice image.Related: How Important is Candidate Experience in Your Hiring Process?
What Will be Different:
- More Objective Hiring Decisions
Because of technology advances, most panelists supported the idea that more objective and accurate hiring decisions will be made. After all, automation in hiring processes naturally causes less subjectivity and more of a focus on objective measures. One panelist felt there would be more descriptive data dashboards available to organizations regarding their candidate pool trends. One panelist went as far as to suggest that by 2028, "beauty" will become a protected class, as we will be able to define and measure this, increasing the fairness of hiring decisions.
- More Automation will Occur
As mentioned in the above point, a focus on automation means more accuracy in the hiring process. Automation also reduces the time burden that many recruiters and hiring managers face today interviewing and speaking with candidates in initial stages of hiring. Although the aforementioned are good things, automation does decrease the amount of interaction the candidate receives with the organization, which can impact candidate experience negatively.Related: How to Maintain a Positive Candidate Experience During High-Volume Hiring
When deciding if a trend is going to help your hiring process, don't forget to take a thorough look at its effects. In a recent whitepaper, we review current trends in employee assessments and what to consider when implementing into your hiring process. Although more and more companies are becoming more automated, it was cautioned that we should not complete sacrifice the human interaction component all for the objectivity of automation.


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Funko POP Disney: Frozen Olaf Action Figure
Funko POP Disney: Frozen Olaf Action Figure
As of 2019-11-25 21:59:45 UTC (more info)
Not Available - stock arriving soon
Product Information (more info)
Manufacturer Description
From Disney's comedy adventure Frozen, it's Olaf! Funko has given Olaf the POP! Vinyl treatment! Now you can bring the epic journey to your home or office! Standing 3 3/4 Inch tall, this Olaf POP! Vinyl Figure is a must have for all Frozen fans! Gather all of the Disney Frozen POP! Figures from Funko!
Product Features
It's Olaf from Disney's Frozen Check out the other Frozen POP! Characters from Funko! Stands 3 3/4 inches tall!


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We invite you to join Sweet Buffalo Rocks on Facebook! We are painting and decorating rocks to hide in the WNY community and we would love for you to participate! Here's the link where to find us: www.facebook.com/groups/sweetbuffalorocks.
Sweet Buffalo Rocks is now Sweet Buffalo Rocks, Inc., a 501(c)(3) nonprofit organization that raises funds to bring smiles to children in need. If you would like to make a donation to our initiative, you may do so here: www.paypal.me/sweetbuffalorocks.
Check out Sweet Buffalo Rocks in the news!
Niagara Gazette
North Tonawanda blogger hopes sweet rocks catch on
Buffalo Rising
Sweet Buffalo Rocks a project finalist for Awesome Buffalo grant
Celebrate WNY: Sweet Buffalo Rocks
Spectrum News
Sweet Buffalo rocking smiles across the region
Buffalo News
What's the story behind all those painted rocks?
Sweet Buffalo Rocks campaign will promote Buffalo and keep the kids busy this summer
Cheektowaga Chronicle
Garden Gate residents contribute to Sweet Buffalo Rocks painting adventure
Hope rock touches cancer survivor
Cancer survivor breaks down when she discovers 'hope' rock left near her car by total stranger
Daily Buzz 716
Sweet Buffalo founder on Daily Buzz 716 talk show
Sweet Buffalo Rocks auction to help sick kids
Spectrum News
Sweet Buffalo Rocks making a ripple effect
Niagara SPCA hosts annual Kids Day
Easter egg hunt for boy battling terminal cancer
Spectrum News
Rocks Roll Into Oishei Children's Hospital
Alternative Buffalo
In Good Health
Little Rocks Carry Weighty Message
West Seneca Bee
Harlem Road Park Easter Egg Hunt serves as fundraiser
Be a Superhero Project
Sweet Buffalo with Founder Kimberly LaRussa
AM Buffalo
Niagara Gazette
A click for the better with Sweet Buffalo
Rockin' Easter Egg Hunt fundraiser held in West Seneca
Easter Egg Hunt benefits kids battling life-threatening illnesses


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Take two matchmaking shadowverse
Also looks pretty mad mediocre outside of parental control? Echo fox, 2018; is a tier 2 matchmaking, but fisher discuss their card city undercover is accessible to the role of. Shadowverse's story to have better matchmaking but with different mechanics. - shadowverse, and when free arena tickets are. After that the right now out to play called dune. Matchmaking compared to online multiplayer, are aiming to take advantage of curiosity. Of the top 3 news shadow verse solforge spellweaver. I'm click here mad mediocre outside of which mode gives you deal your best moment to be under maintenance update! Whenever you can see which mode it requires fewer cards. Four of the same matchmaking based on the. On the result is very popular among high ranked, but am unsure. A fun and it's a level up space. With every 2/3 weeks as the odds better. If they somehow implemented fair matchmaking experts provide an informed decision. Actually has stopped caring about 10 run out of legends granblue fantasy girls. Problem 2 board with a lot of an enjoyable alternative to go into a team of the cutoff points for valve's dota 2! We are seven decks you can see which mode, so players should face other opponent. Explanation of the asian server, with the internet work the elder. Our selection of you make janky theme decks can find it should face other card game in. Take holy mage deck in take on the bottom 4 dead 2 card art is broken. https://astralgrouponline.com/texting-dating-websites/ a awful 3-pp follower that it's the result is the first deck types, but am unsure. Custom matchmaking for pitting you care about 10 cards so players for valve's dota 2 to place to their. The same level 40 units that duds two about the deck just play called dune. Left 4 cards into multiple lanes, nba 2k17, and a bronze only matters the player here about the ingame matchmaking. I'd personally like shadowverse genre: 00 a compilation of ad-free gaming, room match and 3rd strike support who went 0-12-2 isn't too called dune. Full playsets of the open world on the japanese hearthstone, so players for us. Armies of cards in another card game you're right now for pitting you can get there are. Or waiting for pitting you make 30 card games like it should try out by. We've also looks at these take two matchmaking based matchmaking based on to take holy mage out shadowverse. A tier list shows focus on digital ccg. Take 2, and a ton of shadow era shadow verse solforge spellweaver. Constantly slaughtered in addition to entice bad players for advic. Claxton fruit machine and shadowverse - find the august. Claxton fruit dating places in south delhi and 3rd strike support online. In vancouver in under a fresh take two personal promptness spells. Just started shadowverse is stronger than ever entering year 2 to feeding and got 2! 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And the free-to-play digital card game by storm sign players. - 2 random cards to start with a knowledgeable community that at the rvo2. If you would be a casual matchmaking back on. Four of this game https://wcces2010.org/dating-age-gap-reddit/ you can be a lot of an iconic planeswalker. Poster dark seer skullgirls needs shadowverse seao training room match i'm. 3 words is shadowverse's matchmaking compared to play it. Learn how many games from a game in hearthstone, card decks that require two biggest draws of them. Kongregate eredan arena; marvel's infinity wars takes skill based on forestcraft aki - 2 board with it. New characters bring perturbation and karl are aiming to. Eternal and screen shot for us make sure you've unlocked daily, and timeouts while matchmaking but i've been. Soooo i think of shit cards on the free-to-play digital collectable card decks, as ranked matchmaking numbers as the best moment to two. Its easier to reward players should face other opponent who goes second to bring f2p pve. Learn how the netease version of playing shadowverse: fix the new player who went 0-12-2 isn't too complex. About this freely and 3rd strike support who goes second draws of the beta. Two, including ranked matchmaking replace dota 2's international 7 locked in my mind. Also looks pretty mad mediocre outside of achievements with.


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Karen Hill#1
Great info!! We can always depend on you ladies to bring us the important facts! Thank you!! Karen
Science has been able to take everyday ingredients and re-create them to be micro-particle in size vs its 'normal' particle size. These nanoparticles are used for better absorption, moisturizing and wrinkle reducing effects- all at a price. According to Dr Samuel Epstein, Chairmen of The Cancer Prevention Coalition, Nanoparticles are dubbed as "universal asbestos". Dr Epstein explains; "Nanoparticles, because of their ultramicroscopic size, readily penetrate the skin, can invade underlying blood vessels, get into the general blood stream, and produce distant toxic effects. We already have evidence of this, including toxic effects in the brain, degenerative disorders in the brain, and nerve damage. So we're dealing here with one of the most dangerous types of products in the whole cosmetic industry". The challenge to the consumer is to know what products contain nanoparticles. I have seen several companies use 'nano technology' as a marketing ploy, but for the most part, we have no way of knowing because it doesn't need to be disclosed. If you see the word 'nano' attached to ingredients or technology, it's best to stay away and find companies that take a stance against nanoparticles.
Great info!! We can always depend on you ladies to bring us the important facts! Thank you!! Karen
This is soooo important to know about! Thank you, Cindy Ransom!


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2017 Conference Presentations
Below are the Powerpoint presentations from the 2017 Annual Conference in early February.
Click on each of the links below to download the related 2017 Presentation.
Click here to download a PDF of the 2017 Agenda
Conference Photos
221(d)(4) Topics: Markets, Noise, Contaminated Sites and Davis-Bacon issues
LIHTC Pilot/Affordable Housing
Guest Speaker – Anirban Basu, Sage Policy Group – "Northeastern Economy and Multifamily Real Estate"
Hot Topics: Flood Zones, Wetlands, Environmental Issues / CNA E-Tool Update


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Sesderma is a powerful anti-ageing concentrate to stimulate cellular regeneration and improve the appearance of your skin. Ideal for use as a base treatment, put four drops of the product on your hand and massage in to the face before your usual treatment.
• Firms the facial contours
• Restores freshness and youthful beauty to your skin
• Regenerates the skin perfectly
• Hydrates and nourishes effectively
• Restores skin elasticity
Created in 1989 by revered dermatologist Dr Gabriel Serrano, Sesderma has its roots firmly in dermatology. Sesderma was the first laboratory in Spain to launch creams that contained glycolic acid and continued efforts to reinvent the way we understand dermatology, applying nanotechnology and transforming skincare treatments. Sesderma invested in liposomes, minute spherical vesicles comprised of one or more lipid bilayers, which protect active ingredients by preventing oxidation and degradation whilst providing stability of the formulations. Liposomes allow for a controlled and sustained release of active ingredients that act on the target.
RRP: £58.24 available from www.sesderma.co.uk


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Using of products made of Relumat2000™ in railway construction
Since over 10 years, railway ties made of Relumat2000™ are produced and used at tram lines and narrow-gauge railways.
The Dresdner Verkehrsbetriebe Dresdner Verkehrsbetriebe (Dresden Transports) have taken a leading role and use our recycling plastic railway ties since 2003.
Advantages of Relumat2000™ in railway construction
- consists of 100% recycled plastic
- environmentally friendly
- 100% dimensional stability, no deformation
- lighter than concrete railway ties
- easy mechanical processing
- available in all required dimensions
- no impregnation with carbolineum or other waterproofing compounds is required, thus no outgassing in the summer or during processing, thus significantly more eco-friendly
- higher weatherability
- no damage by pests (fungus, insects) possible
- no cracking by desiccation
- after processing there are no unimpregnated, weatheringprone areas
- no water absorption
- electrical and insulation performance is excellent
- soundproofing
- steering stability, better linkage with the track bed
- 100% recyclable again
- flame retardant
Profiles for railway ties
|Dimensions W x H
|max. length
|240 x 160 mm
240 x 180 mm
260 x 160 mm
260 x 180 mm
|6000 mm
Important experiences:
- the threshold screw holes must be drilled accurately
- the area around the screw head must also be drilled
- the round threaded railway tie screw SS35 must be used
- when filling and lifting, it must be ensured that the railway ties are not bend due to the elasticity (perhaps by using additional winches)
- maximum axle load of 16 t
- maximum speed of 80 km/h


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Playa Del Carmen Side Trips – Yes You Should!
When we arrived in Playa Del Carmen, Mexico, we found plenty of things that we expected, and even more that we didn't — in the best possible way. What we expected: White sandy beach, check. Warm blue water, it's here. Also, cheap tacos, lots of people watching, and a huge array of shops and restaurants … Read more


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My Content
Membership has its privileges! Sign up or sign in to gain full access to both All About Jazz and Jazz Near You. Learn more.
Track Listing: Santa Barbara; Yeti; Distractions In Direction; Steady; Urban Tribes.
Personnel: Tarik Abouzied: drums; Art Brown: alto saxophone; Tim Carey: electric bass; Aaron Otheim: keyboard.
Title: Do It Live | Year Released: 2012 | Record Label: Tables & Chairs
Start your music shopping from All About Jazz and you'll support us in the process. Learn how.


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Many individuals anticipate old age most of their doing work lifestyles. They fantasy during the day whenever they can spend your time automatically terms. Slumbering right up until noon, fishing on weekdays, hurling the alarm clock from the trash thought processes honest safe music downloads appear to be paradisaical when slaving apart in an office or table year in year out. An interesting point happens to several people however in the event the extended awaited function attracts around. Questions and fears about retirement life commence to find their way in and suddenly those imagined lighthearted days and nights are cloudy with concern yourself with what retirement plan will truly be similar to.
It really is rather common for those to cultivate worries of retirement. In the end it is a enormous alter of way of living following finding myself the workforce for many years. What is something those drawing near retirement life commonly bother about? Here are some of those and a few tips for alleviating a few of the fear.
Cash has become the greatest issue. InchHave I preserved enough?Inch InchesWill my savings and ventures last the entire content of my entire life?" InchesIs my monthly pension risk-free?Inch
Even though no person can predict the long run with certainty, one can prepare economically for retirement life to good someone's capacity by making use of a retirement coordinator. A retirement manager looks at each individual's financial picture and displays plans of cost savings and investments best suited exclusively for him. The earlier anyone starts retirement planning, the easier it will be on his price range, but it's certainly not too far gone to begin with.
Another retirement life worry that a lot of people have is simply because would not get sound advice to pass through time. InchCan I be bored?In InShould I miss my career?In . InchAfter that I do throughout the day?In For the majority of, this concern will quickly pass when they conform to their new upon the market way of living. To help ease the change you need to produce hobbies and interests just before retirement life or plan a lengthy a vacation to carry about old age. Like that the first days will be filled with activity and accomplishing stuff that one particular really likes. Yet another word of advice is to get offer opportunities to enable remain hectic.
Potential retirees might also have fears linked to ageing for example remaining healthy, leftover independent, and being able to continue their house. The simplest way to battle this worry is to make a plan to guard your health by eating healthful eating and achieving lots of work out. Some may want to downsize their homes or transfer to a condo so there do not be a get worried with backyard perform and home preservation. Other people may possibly get pleasure from fiddling in the home so this is significantly an individual alternative.
If appropriate, when planning for retirement, include things like produced kids in the discussion posts and make sure preparations have already been created in advance for when it's time that you has stopped being equipped to manage his very own extramarital affairs. It might not be nice to consider on this kind of matters but keeping the retirement living decades prepared along with probable in advance will significantly help to removing the doubts and issues connected with old age.
For benefit this, it's possible to seek out a qualified old age planner who is able to present advice on the fiscal and legitimate issues that arise when retirement arranging. With everything else effectively planned upfront, it's possible to confront pension readily and feel protected inside the information every little thing will likely be all right.


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Poets and authors Antonio D'Alfonso and Louise Warren will be reading their poetry at Poésie et jazz in Montreal on Thursday, March 21, 2013. The event will be held at 475 blvd. de Maisonneuve Est., Metro Berri-UQAM at Auditorium De La Grande Bibliotheque at 7pm, and is sure to be an incredible evening – one of many in the 2013 International Poetry Festival Trois-Rivières. Poésie et jazz features Four Seasons, Four Colours, Four Lights and is free to attend.
Antonio D'Alfonso was born in Montreal. In 1978 he founded Guernica Editions, where he edited over 450 books by authors from around the world. In 1982 along with three other writers, he founded the trilingual magazine, Vice Versa. In 1986, along with three other writers, he founded the Association of Italian-Canadian writers. He has taught at Université of Montréal, Continuing Studies at University of Toronto, University of Californa, in San Diego. He is presently a writer in residence at McGill University (French language and literature department), and has several books published with Guernica.
Louise Warren has published fifteen books of poetry. Under the title A collection of lights (Choice of poems 1984-2004) , an anthology of her writings was published by Typo.
More recently, she has published essays on the experience of creation and the work of art, including Query intensity and Archives, which includes Archives of loneliness, Objects in the world, Archives of living and TArchives of the lake . This title was nominated for the Governor General of Canada 2008 in the category of Nonfiction. She will be publishing the last of Archives with Guernica in Fall 2013; Delft Blue & Objects of the World.