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ICSE Result 2019
Indian School Certificate Examinations Board, Delhi (ICSE) will publish ICSE Result 2019 on the official web site. The students who appeared in ICSE 10th class Exam 2019 were waiting for their result at last one month. The examination was done in the Month of February and March, 2019. All passed candidates will able to take the admission in 11th class. All the students can now check their roll number wise, district wise and name wise from here. We have provided ICSE Result 2019 only on the official web site. We are also providing a direct link for ICSE 10th Result 2019 download. The direct link will help the candidates to checking their results online and easily. You can check all further necessary details on the website.
ICSE 10th Result 2019
The board had provided date for the result declaration on the official web site at 2 week ago. You can check their examination result by entering correct required information and it is best method to get their examination result. We as know the ICSE X exam is a central level examination. Indian School Certificate Examinations Board, Delhi every year organizes examinations 10th and 12th board examinations. According to official news a large number of students have appeared in this written exam. Now all students who have appeared in this examination they can check their ICSE Result 2019 on this page. Normally a huge number of students first time gave Board examination in this year so they were excited for to check their ICSE X Result 2019.
ICSE 10th Class Results 2019
|Name of the Board
|Council for the Indian School Certificate Examinations
|Name of Exam
|12th Examination
|Date of Exam
|26th February to 28th March 2019
|Declaration About
|ISC 12th Result 2019
|Status of Result
|Not Declared
|Availability of Result
|Last Week of May
|Official Website
You will able to check their ICSE Result 2019 after the deceleration. The board will be given a second chance to all of those students who are not passing in the board examination of ICSE 10th class. They can apply application form to next session year exam. According to local newspaper, last year (2016-17) 95% candidates have passed in the examination. Mostly ICSE 10th Results 2019 are very important for all students (Boys and Girls). All regular students will able to check their CISCE 10th Result 2019 on official website. Your passing is depend on yours preparation. We are suggested all present students that touch with me for lasted update. A large number of candidates across the country have appeared for the 10th class examination at different centers in India.
दोस्तों सीआईएससीई बोर्ड दसवीं परीक्षा २०१८ में इसबार लगभग २लाख अभ्यार्थी उपस्थित हुए हैं। अभी तक बोर्ड ने रिजल्ट की डेट घोषित नहीं की है, लेकिन ताजा जानकारी के अनुसार आईसीएसई का परिणाम जल्द ही ऑफिसियल वेबसाइट पर घोषित कर दिया जायेगा। आप अपना रिजल्ट निचे दी गयी लिंक पर जाकर चेक कर सकते है।
cisce.org 10th Result 2019
The Council for he Indian School Certificate Examinations shortly name as CISCE. It was established in 1958 by the central govt. The major headquarter of this is located in Delhi. Private candidates are not permitted to appear for this examination. The list of toppers will be displayed by the board in the official website. The written exam was organized in the two parts (half yearly and yearly. The Half yearly exam was done in the Dec month 2017. Many students are doing wait for ICSE Result 2019 release's date. It is expected that results in the year 2019 will touch the mark of almost 88%. Mostly examination result is very important point in the student's life. The original marks sheet will have to collect from the office.
The CISCE has successfully conducted the 10th Examination from 26th February to 28th March to 2019. Now all appeared Students are start to search ICSE Result 2019 online. The Board did not yet declared the exact date of 10th Class Result. But it announce soon on the official website. So all Students need to follow the official website or our this page regularly and get all latest updates of 10th Exam Results. When the Board has announced the Results, we will update here. So all Students can able to check your Exam Result after official announcement.
Steps to check ICSE 10th Results 2019
- First of all log on to official website of CISCE
- On home page you will see the link for ICSE Result 2019.
- Click on that link and you will be able transferred to another window.
- Enter you roll number or seat number.
- You can see your result on your device.
- You can also save this file or can make Pdf of it on your computer by clicking on right click button.
- Take mark sheet and certificates from your respective schools within couple of days.
Click here to Check ICSE 10th Result 2019
Also Check:-


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Many investors aren't aware of the fact that stock markets don't do a good job reflecting the real economies. For instance, the markets usually contain too many high-risk industries such as pharma or banks and not enough service providers.
The Swiss SMI (Swiss Market Index) for example has seven times more pharma companies and twice as many banks as Switzerland itself. In other words: SMI investors are speculating on pharma and banks when they're buying the SMI as an index fund.
That's not what most investors want, but many of them still buy index funds without thinking about it.
Why is the index fund not the same as the market? It's very easy: Nobody makes sure that companies are added to the stock market in ratios that are representative. That's why there are many more companies from industries that need the stock market and fewer from industries that are less dependent on the public capital markets. You can find more information about this in our free (Investing Handbook). Service providers are less dependent on the capital markets. IKEA, for example, is still family-owned, and Migros and Coop aren't on the stock market either.
So when I saw Adecco in the top 10 list of the SMI, I decided to buy the stock; despite the fact that I was on holiday and was only looking at the SMI top 10 for fun.
It wasn't too much work though: I bought 70 Adecco shares at market on the Swiss stock exchange with my online broker Strateo.

subset: commoncrawl


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2016 Conference Highlight: Genetic Testing
2016 Conference Highlight: Genetic TestingJuly 27, 2016 No Comments on 2016 Conference Highlight: Genetic Testing
For the very first time, a patient organization was able to offer genetic testing to individuals with neuromuscular diseases. Prior to this weekend, a doctor would bring in groups for this type of testing and, this weekend, we were able to genetically test through saliva for over 30 different rare genetic diseases without insurance or a doctor.
Thank you to the LGMD consortium for allowing us to be a test-taking location and to be the first patient group to offer such an amazing gift to our NMD community at our Speak Conference. Thank you to Genzyme for partnering with us this conference and sharing your information with our group!


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HyPix-3000 is a next-generation two-dimensional semiconductor hybrid pixel array detector (HPAD), pixel size of 100 um², designed specifically to meet the needs of the home lab diffractionist.
>> See more
Small angle X-ray scattering (SAXS) Kratky camera system
Ultima IV
Hochleistungs- und Mehrzweck-Röntgensystem für Forschung&Entwicklung bis hin zur Qualitätskontrolle
Hochentwickeltes und hochauflösendes Röntgensystem, betrieben von Guidance Expert System Software
Small-angle X-ray scattering (SAXS) is a small-angle scattering (SAS) technique where the elastic scattering of X-rays by a sample which has inhomogeneities in the nanometer range, is recorded at very low angles (typically 0.1 - 10°). This angular range contains information about the shape and size of macromolecules, characteristic distances of partially ordered materials, pore sizes, and other data. SAXS is capable of delivering structural information of macromolecules between 5 and 25 nm, of repeat distances in partially ordered systems of up to 150 nm.*
*Glatter O, Kratky O, ed (1982). Small Angle X-ray Scattering. Academic Press. ISBN 0-12-286280-5.


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Future B2B US Industry Innovator Awards Ebook Now Available
ALEXANDRIA, VA.—The first ever iteration of NewBay's Industry Innovator Awards have been unveiled, and interested parties can find all the nominees and winners available via a new ebook.
Presented by six NewBay publications—TV Technology, Digital Video, Video Edge, Radio magazine, Radio World and Government Video—the Industry Innovator awards are designed to spotlight the people behind the companies and technologies that drive these industries. Winners were selected for their professional achievements, technical and business innovations and continuing influence within their industries.
The "Industry Innovator Awards 2017" ebook showcases the nominees and winners, as well as their contributions and continuing success.


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Have you signed up to be a part of my mailing list yet. If you want to know before anybody else about the release date of DART Book 3- A Lifetime with Mercuria, get yourself over to http://eepurl.com/oE5Y1 and get signed up.
All the most up to date info on all of my books is available her and at the end of May, one lucky subscriber will receive a free voucher for one of my books on Amazon.
M. W. Rowe


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Falling Off the Skincare Wagon
In the interest of full disclosure, I've fallen off the skincare wagon. Hard. Toppled right off the backside of it and have laid in the mud for far too long. My skincare routine and I haven't seen each other in an alarming amount of time and this post more or less serves as a slap on the wrist to myself and an encouragement to you to not be like me.
I'm blessed with very good skin. Minimal blemishes, fairly normal to slightly dry skin that doesn't make a fuss or fight with me. I definitely take it for granted and this good skin is probably why I don't pay as much attention to a regular skincare routine as I used to and should. I went through a phase at the start of the year when I went skincare crazy. I filled a bin full of wonderful products and enjoyed my evening and brief morning visits to the bin to pamper my skin. But I honestly can't see a difference between my skin then and my skin now. I know that regularly washing my face and taking care of my skin is important, but there has never been obvious changes to my skin to encourage me to keep going.
I think the only way I pull myself out of the mud and back onto the skincare wagon is by creating a very simple, easy to do no matter what routine that only uses a couple of products. My excessive skincare excitement was my demise. Now I have to rekindle my relationship with this beautiful bin of products and get my skin back to where it needs to be, regardless of if I see any obvious improvements. Here's hoping that this post written with my head hung low will be a wake up call to myself and my bad skincare ways.
What's your skincare routine like? Do you sometimes find yourself falling off the skincare wagon?
xoxo Kayla


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iPhone 7, Ear Pods with Lightning Connector, Lightning to 3.5mm Headphone Jack Adapter, Lightning to USB cable, USB Power Adapter, and documentation.
iOS 11
Retina HD, 4.7-inch LED backlit widescreen with next generation Multi-Touch display
12MP wide-angle and telephoto camera
A10 chip with 64-bit architecture Embedded M10 motion coprocessor
Built-in rechargeable lithium-ion battery. Talk time up to 14 hours on 3G.
Weight - 138 grams. Height - 138.3mm. Width - 67.1mm. Depth - 7.1mm.
Nano-SIM, not compatible with existing micro-SIM cards.
LTE Advanced (Up to 450 Mbps)
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Mary Katharine Ham has made this observation astutely again and again: The "savings" in the debt ceiling deal are simply cuts to projected future spending. But she's never made the point more funnily than in this video. It's less than 30 seconds, but it packs a punch!
Vodpod videos no longer available.


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Click here to get the answers to the most commonly asked RBL questions.
Review of Biblical Literature Blog
The One Who Is to ComeFitzmyer, Joseph�A.Grand Rapids: Eerdmans, 2007 pp. xvi + 205. $18.00
Description: "Messiah" is one of the most contested terms in Christian reflection, with many people reading the concept back into early Old Testament texts. In The One Who Is to Come Joseph Fitzmyer contradicts that misreading, carefully tracing the emergence of messianism in Judaism to a much later date � the second century B.C. The One Who Is to Come begins with a linguistic discussion of the term "messiah," then demonstrates the gradual emergence of the idea of a future, dynasty-continuing David, before finally examining the �anointed one� language in the latest biblical text, Daniel 9. It also examines the use of the term in the Septuagint and extrabiblical Jewish writings, as well as the New Testament, Targums, and the Mishnah. Fitzmyer�s masterful study presents a novel, biblical thesis that will appeal to scholars, students, and all who wish to investigate the complex history of messianism.
Subjects: Methods, Historical Approaches, History, Form, Tradition and Redaction Criticism
Login to Read the Review(s)
You must be a member of SBL to read the review(s). In May 2019, SBL improved security of its main site with a new login procedure that requires an email address and a password, instead of an SBL member number. RBL�s login procedure is now synched to SBL�s. Please use your email address and SBL password to log in to RBL. Your use of this site indicates your acceptance of RBL�s Terms of Use.
I don�t remember my SBL password.
Join SBL or renew your membership to read the review(s).


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joe kubert
CBR SUNDAY CONVERSATION: David Marquez
David Marquez studied the greats to develop the eye-popping visuals for "The Joyners in 3D," and he spoke to CBR about its 3-year journey & the art of storytelling.
CBR TV @ NYCC 2012: Andy and Adam Kubert on Their Father's Legacy, School & More
Adam and Andy Kubert make their CBR TV debut, discussing their careers and their recently-departed father, comic book legend Joe Kubert, sharing advice for aspiring artists and more.
NYCC: Adam Kubert Discusses The Kubert School
Adam Kubert and Anthony Marquez spoke about the Kubert School, its curriculum and the pursuit and rewards of an artistic profession during a panel at New York Comic Con 2012.


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I have a big ol' Mom buzz on. My bigger boy called me from his grown-up life in Denver for feedback on something he experienced. He did this about a month ago too. We had another great talk and at the end he told me he thought I was awesome, he's proud of me, that talking to me is helpful these days, and he wants to come have Christmas with me. (!!!!!!!!)
It's as good a time as any to launch ASK A CRONE, for those seeking advice from mature persons and who would rather be shot dead than talk about a particular thing with their actual parents.
I promise to provide thoughtful feedback based on personal experience. (Live a while, shit goes down.) If I don't think I have anything useful to offer I will say so. Anyone wanting to chime in is welcome, especially others of an interesting age.
So, who needs another cookie? More milk? let me get you a quilt, you look a bit chilly. Is there anything we want to talk about?


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BOSTON (MarketWatch) -- Bank of America Corp. BAC, -0.69% on Friday moved to offer 1.25 billion shares of common stock. The government has told Bank of America it needs to raise about $34 billion to make up for a capital shortfall. The company plans to periodically sell shares, rather than a single offering. Bank of America shares were up about 5% to $14.19 in midday trading Friday. (An earlier version of this story incorrectly reported that Bank of America had priced the offering at $8.79 a share. Instead, the 1.25 billion shares of common stock will be sold over time at market prices.)
B. of A . to sell 1.25 bln shares of common stock
Quote References
-0.24 -0.69%


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Lots of parts, need to get rid of the car one way or another in 6 months.
Lots of parts, need to get rid of the car one way or another in 6 months.
I'd like to buy the rear buttresses and associated parts.
Also, if you have brown or tan interior parts, I'm interested.
Check your PMs
I am up the road a few miles in Eatonville. I can come by in 4 days when I get back from work and probably take most of it off your hands. PM me
If the light stalk is the same as the coupe I am interested
1978 Lancia Beta Coupe
2001 BMW 325ci
FWIW Beta/Beta stalks go '75 - '79 then '81 - '82. IIRC Scorp - X 1/9 stalks are diff,
i.e. blinkers.
Last edited by davidb; 18th August 2019 at 12:33 PM.
do you have rear calipers? I just sheared the bleed nipples off both rears on my scorpion! thanks!
Is the motor available?
Why not get rid of the whole car? Is it severely rusted? Any pictures of it?
I really need a $500 rusty Beta to turn into an italian track car.
Current Lancias:
1981 Beta Zagato
1979 Beta Zagato
There are currently 1 users browsing this thread. (0 members and 1 guests)


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the presence of
your employees.
Emprez lets you create and publish schedules easily and efficiently. We offer several tools for you to choose from to help tailor the process to fit your needs.
As soon as schedules are complete, you can make them available in real time for your employees via the Emprez mobile application, the Emprez employee portal or directly on the physical punch.
The Emprez schedule verification system flags any scheduling conflicts, errors or omissions.
Time and Attendance
Employees can punch using the platform of your choice: a dedicated touch screen, the Emprez mobile application or the Emprez employee portal on a tablet or computer. Emprez compares the actual punched times with the planned schedules and highlights any discrepancies making the approval process fast and efficient. Time and attendance data is electronically archived for your future reference and reporting needs.
Emprez manages breaks, meals and job changes in addition to vacation, authorized and unauthorized absences, statutory holidays, time banks and more.
Exporting Payroll Data
The data is formatted for export to your current payroll system. Get an accurate calculation of hours worked, overtime, vacation, training, hours banked, shift or job specific bonuses and much more. Avoid manual transcription errors and unnecessary paperwork.
Emprez is compatible with the majority of payroll systems including: Desjardins, Nethris, Sages, Acomba, ACCEO, Hopem and Azur.
More than 30,000 people are managed daily by Emprez.
How much will you save?
Talk to one of our payroll experts and find out how much businesses like yours are saving with Emprez.
It's the best way to find out what Emprez can do for you.
Save management time!
Regardless of the number of employees they have, our customers report saving 50% of the time previously devoted to management of scheduling, timesheets and payroll.
(Survey conducted September 2016 with 680 clients)
Companies with more than 300 employees


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Each section has a varying number of rows and seats per row. If you already have tickets, find your seats for row and seat numbers.
The home sideline is located near sections 16, 117, 119, 14 and 15.
The chairback seating chart and list of sections and rows can be found here.
A list of visitor fan sections and a seating chart are available here.


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Campsite in Brittany
Campsite by the sea
Are you looking for a campsite beside the sea? Our campsite in Brittany sports 4 stars and is situated in southern Finistère in Plobannalec-Lesconil. Our mobile homes and pitches are set up along the Steir river where its waters meet those of the Atlantic ocean at the heart of the bay of Lesconil. Our campsite by the sea in Brittany is located 5 minutes from Sables Blancs beach, a beach of fine sand accessible by foot or by bike by following a safe bike path. From the Breton Ocean campsite, you have an unbeatable view of the sea and also the Kerlut manor, a stone building from the 19th century that is now hosting marriages and receptions.
Campsite in Finistère
By choosing our campsite in Finistère, an undetectable universe opens itself up to you. Enter the inspiring atmosphere of Pont-Aven, a village where Gauguin and other painters from the school of Pont-Aven used to stay. Lovers of old stone and of typical villages must meet Locronan, one of the most beautiful villages in France. It hosts several craftsmen and women – glass-makers, textile workers or painters – and the theatre holds, each summer, an market for arts and crafts. For hiking or mountain-biking, thousands of kilometres of paths await you. Head in the direction of Lesconil, Loctudy or Guilvinec by stopping in front of the menhir of Lehan, a megalith dating back to the Neolithic period (3000 BC).
We suggest you a selection of our favorite places not to be missed when discovering our beautiful Brittany region.
Thanks to Haliotika, in the port of Guilvinec, discover the life of a fish market, with the return to port of the trawlers at 4-30pm. Also on offer are a number of guided, themed visits as well as entertainment for children. Then go on to the Comptoir de la Mer shop to buy your Breton souvenirs and visit the market in Guilvinec every Tuesday and Sunday.
The Eckmuhl lighthouse in Penmarc'h takes you up to the top from where you have a magnificent view of the Breton coast from the top of its 307 steps. Then visit the port of Saint Guenole and take the "feet in the water" trail to Kerity.
La Torche is among the great names in "surfing sports" in France. Just 15 minutes from Yelloh Village l'Ocean Breton, you can discover the beauty of this wild coastline. Not far from there drop in and see the Chapelle de Tronoen, the oldest wayside cross in Brittany but also a prehistoric site, well worth the detour!
Impossible to come to Brittany without visiting one of its numerous, unspoilt, charming islands. Discover Benodet then take the boat to out along the river Odet and out to the Iles Glenan.
Finally we encourage you to visit the beautiful towns of Concarneau, Quimper, Locronan and Pont Aven, true jewels in our history and immersion into a time gone by.
Tourist map of Cornouaille Ouest
Pointe du Raz / Cap Sizun / Baie de Douarnenez / Pays Bigouden


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SAN FRANCISCO--Since I was one of the first people to arrive Friday night for a preview of this weekend's cocktail robots exhibition here, I was going to get the first drink.
David Calkins, one of the organizers of the San Francisco version of Roboexotica--an event that has been taking place in Vienna, Austria, for a decade--had set up his robot, Chapek, and, determining it was ready, asked me to tell the machine what I wanted to drink.
This was after, of course, Calkins had finished getting Chapek ready to go.
"Let's see if it turns on and explodes," he said, "which it has in the past."
He flicked a switch and Chapek was ready.
"Hey," he said, pleased. "It didn't."
Chapek, which is named after Karel Capek, who coined the term "robot," is a small robot with a mischievous face, wiry metal arms, and an attached control box where you tell it what kind of cocktail you want it to mix up and serve you. The choices? Gin and orange juice, a gin martini, a vodka martini, and a screwdriver.
I'm not much of a martini man, and not wanting any gin, I switched the controller over to screwdriver, and pressed the button that would set Chapek in motion.
Sure enough, it came alive and slowly, its arm began to swing in the direction of four bottles that were suspended and awaiting martini glasses. Chapek swung the glass in front of the vodka, paused while some of the liquor poured in, and then continued on toward the O.J.
Finished, it reversed directions and headed back toward the beginning, where my hand was eagerly awaiting my beverage.
But just as it reached that point, the arm sped up, and instead of stopping and serving my drink, Chapek slammed the glass against its body, spilling my screwdriver all over itself and its interior electronics.
"I suppose I should look at the (computer) code," a chagrined Calkins said, before explaining to someone who had just wandered by that, "Chapek is being greedy again. He made the drink and then he stole it."
Indeed, while the spilling of the screwdriver had seemingly fried Chapek's microcontroller, rendering the cocktail robot useless for the moment, Calkins wasn't all that perturbed. It was clearly nothing that he or his colleagues hadn't seen before.
"Chapek, he's an alcoholic," said Simone Davalos, Calkins' co-organizer. "We can't take him anywhere."
For a decade, Roboexotica has been a growing hit in Vienna. Now, it has come to San Francisco, where it will be open to the public on Saturday from 8 p.m. to 2 a.m. at Space, 354 5th St.
On Friday night, there were only a few cocktail robots set up for the invited guests to see. So I was not able to see some of the machines that will be on display on Saturday, such as one that can test your blood alcohol content, or another that I believe is intended to blend a fruity drink while shooting out big fire.
But one that was on hand was Davalos' creation, which she called El Espanol Borracho.
This small robot is a cylinder that, if you weren't paying close attention, you might mistake for a kettle. But it's attached to a small container of high-pressure fuel and has spigots coming out of it that serve up the booze.
Davalos had the robot serving Spanish Coffee, a particularly strong mix of several alcohols, but at first she couldn't get it to do just what it was supposed to.
Clearly, fire was supposed to be involved, because she began to tell a funny story.
"Last year, I did this and set my arm on fire," she said. "And I didn't notice at first because the floor was also on fire."
She tried to get it running properly again, but still, no fire erupted. Instead, we all began to smell a very strong odor of fuel.
"David, unplug me please," Davalos urged Calkins. "Quickly."
By now, the robot had squirted out a full cup of alcohol. And for a moment, a small halo of flame shot out of the side of the robot, illuminating the cup.
Someone asked, "What does it taste like?"
"Probably fuel," Davalos joked.
She tinkered with it a little more and then tried again. And this time, it worked: Huge jets of flame shot out the side of the little robot, blasting the drink.
We all cheered. And then someone noticed that the floor had caught fire a little bit.
"Yeah, that happens," Davalos said matter of factly, before stamping out the little flames with her foot.
Over on the other side of the room, Magnus Wurzer, a founder of the Austrian Roboexotica, was setting up Chris Veigl's Mind Reading Martini Maker.
This looked a little bit more like a science experiment than a robot, but Wurzer explained that the key to this robot is software that is "customized for martini mixage."
He explained that the robot measures how many alpha waves on average are being detected by an electroencephalogram (EEG), and that the more alpha waves it finds, the drier the martini it makes.
Back in Vienna, Wurzer said, Roboexotica has grown to include dozens of cocktail robots, as well as others that people bring just because they're cool.
For example, he said, someone had recently brought a robot that was capable of flipping a cigarette into peoples' mouths.
Meanwhile, Calkins was trying to get Chapek up and running again, but he was frustrated by the effects of the robot's drinking problem.
"Orange juice and microcontrollers do not mix," Calkins said, exasperated.
A few minutes later, though, he offered, hopefully, "(the microcontroller) might be drying out."
To which Davalos deadpanned, "Every robot bartender needs to dry out once in a while."
On June 10, Geek Gestalt hits the highways for Road Trip 2008. I'll start in Orlando, Fla., and visit many of the South's most interesting destinations. Stay tuned, and be sure to keep up, both now and during the trip, with what I'm doing on Twitter.


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Hellooooooo everyone....!!! Here I am back with a cup of Indian Architecture .. just to refresh the memories of past posts... and poke into the world of beauty and royalty again.
Few pictures ...of intricate work on stones..marbles ... etc. with great looks.. perfect measurements and most importantly...scientifically meant and build up. Lots to learn from such great work and amazing world of design..and architecture.
Home »Unlabelled » Beauty of Indian Architecture.
Beauty of Indian Architecture.
1:06 AM Unknown


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From The Blog
Kryptid at Biggs Harley Davidson May Ride 2019
Kryptid takes the mainstage at Biggs HD May Ride 2019
Kryptid rocked the house at the Biggs Harley Davidson May Ride 2019 event, hosted by Clint August of 101.5 KGB radio in San Diego! Clint broadcasted his show from the event during his daily timeslot. The event included a Lucha Libre wrestling ring, onstage musical performances, local vendors, and many other family friendly activities.
Kryptid sits down with "The Dusty Futon" podcast
Prior to and following their performance, Kryptid was invited to sit down with hosts Tyler and Big Jon from "The Dusty Futon" podcast. Links to the podcast will be posted here when available but until then, check out a preview of the video podcast from their sit-down prior to their performance here.
Kryptid Happenings April 2019
Keona celebrates the big 1-8 with Nita Strauss!
Keona officially entered adulthood and celebrated in style in Hollywood with none other than legendary guitarist Nita Strauss of Iron Maidens and Alice Cooper fame!
Keona also took the opportunity to get a custom fit over at the PRS Artist Studio in Burbank.
Squiggy loves Kryptid!
Loudwire Gear Editor Carmen Mark DiGiacomo, better known as "Squiggy", wanted to let us know how much he loves Kryptid in typical Squiggy fashion:
Keona included in San Diego Reader's profile of young guitar heroes


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Even the most resistant of us have to concede that summer is now over. There are positives to this, as there's now an excuse for some warming comfort food.
This vegetable casserole uses seasonal ingredients. There are lots of glorious root vegetables, plus seasonal colour with pumpkin (carving leftovers maybe?) and butternut squash. The recipe is stuffed with vitamins, minerals and fibre. Carnivores can always add a few rashers of fried bacon for a different flavour.
This recipe can be left unattended in a slow cooker for up to six hours. If (like most of us) you are out of the house for longer than that during the week, either attach a timer to the cooker or make this at the weekend. Alternatively cook this in a conventional oven for a couple of hours.
Make as much as you like, because it will freeze for future home-made ready meals.
There's no need for precise quantities, use as much as will fit into your casserole dish. Feel free to vary the vegetables. All veg except the carrot should be peeled and chopped, carrot just needs slicing.
Butternut squash – remove seeds
Sweet potato
Garlic – peeled and crushed. 2 or 3 cloves are usually plenty.
Pumpkin flesh
1 tin chickpeas, drained
Salt and pepper
Fresh parsley and fresh coriander – chopped finely
Vegetable stock – from a cube or sauce pot
Cooking oil
yum - bring on the random veg! Also good to have a slow cooker recipe with a workaround for a real working day length.
This was very easy and is versatile for whatever vegetables you have in. I added some chilli and crème fraiche, makes it much tastier.
I never waste pumpkin - just peel and cut up the flesh into cubes, then freeze. You can use it in soups, stews like this recipe, curries and even cakes. Don't waste your pumpkins!!
chuck it in and see what happens - my kind of cooking too! I hope all those carved pumpkins get used in this, otherwise the waste must be shocking.
This sounds incredibly easy and idiot-proof -perfect for me! Personally, I would exchange the chickpeas for red lentils in order to thicken the stew, and add a bit of curry powder.


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Sewing it all together
Wednesday, 30 September 2009
Home again
Home again and I've very busy with all sorts of domestic things, catching up with post, washing my fabrics etc etc. I have sewn in the evenings, the binding on one quilt and quilting the border on another. More anon. Meanwhile here are pictures of "our" house in Portland and the view across the street through our lovely flowers to the beautiful garden of my fellow quilter opposite. I've also included the quintessential Douglas firs against an Oregonian bluest of skies taken in Hoyt arboretum.
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The World AIDS Day
Tuesday, November 28, 2017
The World Aids Day is an international event held on 1st December every year. To promote care and support for people living with HIV / AIDS, our Red Cross Youth Unit organized the Red Ribbon Day on 28th November, 2017. Activities including a display board exhibition, putting on red ribbons and writing caring cards were held. We hope our schoolmates can accept and show care for people living with HIV / AIDS.


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The Characteristic Function from a Family of Truncated Normal Distributions
9 Pages Posted: 15 Jan 2012
Date Written: 2002
The Characteristic Function from a Family of Truncated Normal Distributions -- Solution proposed by Karim Abadir and Tassos Magdalinos. The posers of the problem have raised an important question. We can offer a solution to a more general problem, which covers characteristic functions of continuous distributions. We then use these results to obtain formulae for the moments, whose existence is guaranteed because of double truncation. We give alternative formulae for the characteristic function (and also for the moments) because some are easier to apply than others in different circumstances. We illustrate some of the general formulae with two common distributions.
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In coordination with the Federal Government of Somalia, U.S. forces conducted an airstrike targeting al-Shabaab militants in the vicinity of Haradere, Somalia, on October 12, 2018.
We are currently assessing the results of this airstrike, which targeted only al-Shabaab militants.
U.S. forces will continue to use all authorized and appropriate measures to protect U.S. citizens and to disable terrorist threats. This includes partnering with AMISOM and Somali National Security Forces (SNSF) in combined counterterrorism operations and targeting terrorists, their training camps, and their safe havens throughout Somalia and the region.


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In light of a previous post on Somalia and Somaliland, I recommend a new paper by Nicholas Eubank, a PhD student at Stanford's Graduate School of Business. He notes the parallels between theories of the role of taxation and political accountability in state formation in early modern Europe –
In these historic cases, government dependency on local sources of revenue provided those in control of economic assets with significant leverage over the government which they were able to use to demand the development of more accountable and representative political institutions though a process often referred to as 'revenue bargaining.'
– with the experience of Somaliland over the past two decades. Much depends, Eubank suggests, on whether a country has abundant point-source natural resources that can be seized by a powerful state with relative ease or if its productive resources are more diffuse and mobile:
In these contexts, offering political concessions in exchange for voluntary taxation may be a far more efficient means of collecting revenues, which is particularly important during periods when a government is under financial stress.
This connection between taxation and political accountability also has potential implications forcurrent debates over appropriate levels of foreign assistance and concerns about consistently highlevel of foreign aid provided to countries in sub-Saharan Africa. Given the levels of foreign assistance provided to many developing countries today — assistance which reduces government dependency on tax revenues — this is more than an academic question. There are 16 sub-Saharan countries in which the ratio of foreign assistance to government expenditures is greater than 50%. In ten of those countries, foreign assistance is equal to at least 75% of government expenditures. Indeed, Brautigam and Knack (2004) find that high aid intensity is associated with deteriorating scores on the International Country Risk Guide index of expropriation risk,corruption, and bureaucratic quality as well as lower tax collection efforts.
Moreover, these ideas about tax dependency and political accountability are consistent with studies that find easy-to-control natural resource endowments (which reduce governmentdependency on taxation and thus decrease the bargaining power of citizens) — are associated with more autocratic governments and poor governance (Jensen and Wantchekon 2004, among others)
Because Somaliland has never received foreign assistance, its government has had to coax tax revenues from a population that is not easily dominated through force. Pastoral farming and animal husbandry, and not point-source natural resources, have long formed the backbone of the Somaliland economy. "Revenue bargaining" has thus been central to state formation in Somaliland, and the emergence of inclusive, represenative institutions.
The most provocative takeaway from Eubank's paper is perhaps the following:
[T]his analysis does suggest that the volume of foreign aid that Somaliland would likely receive with international recognition could harm the relationships that have helped shape Somaliland'spolitical success to date. The time may come when Somaliland's political institutions are strongenough to absorb some amount of foreign assistance, but for the time being, resisting the urge toreward Somaliland's government with regular flows of foreign assistance is its best hope ofencouraging the country's continued success.
This doesn't mean that foreign assistance is always a bad idea, but it certainly suggests that it can disrupt a constructive process of "revenue bargaining" that can yield a more accountable and effective government.


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Antibiotics are drugs that are used to kill the infection causing bacteria. This is done by killing the bacteria or by preventing them to replicate or reproduce further. Literally, antibiotics mean "against life". Any medicine that results in destroying the germ cells in the body are known as antibiotics. The first antibiotics were discovered in around the year 1920. Moreover, they became easily available to the public around the time period of 1940s. As a result, life expectancy took a rise, surgeries got less riskier and infectious diseases were not seen as deadly diseases anymore.
1.How do antibiotics work
There are many different types of antibiotics, but they perform their task in two different ways:
- A bactericidal antibiotic, for instance penicillin, kills the bacteria present in the human body. These medicines are designed in a way that they will interfere with the production of the cell wall of the bacteria or even the contents of the cell. There is a molecule named peptidoglycan present in the cell wall of a bacteria that strengthens it and also helps the bacterial cell in opposing the osmotic pressure of the cytoplasm.
- On the contrary, bacteriostatic antibiotics are designed in such a way that they will stop the bacteria from any further multiplication in the body. Basically, in this process, the DNA replication of the bacteria is prevented. For example, ciprofloxacin. This method may not be effective in curing the disease but these drugs are beneficial in means of preventing the bacteria to spread in the entire body.
2.What happens when an antibiotic enters the human body
Antibiotics start their function as soon as you start to use them. But this does not mean that they will work immediately, it might take two to three days to make an infectious person feel better. This usually depends on the type of infectious disease the patient is suffering from. Antibiotics are taken orally and reach the stomach. From the stomach, the antibiotic is partially absorbed and then reaches the small intestine where main absorption occurs into the bloodstream. Now that the drug has entered the blood, it will sense the bacteria nearby it and attach to it. Now further actions depend on the type of antibiotic taken as per the infection, as mentioned above.
3.Antibiotic resistance
Antibiotic resistance is usually experienced due to misuse of the drug. The patient might feel a lot better in a few days of taking antibiotics but that definitely does not mean that they can quit the course of medicine prescribed by their doctor. This is a huge mistake done by many patients. This can result in antibiotic resistance. This means that the next time this patient gets ill with the same infectious disease, the same antibiotic may not effect them this time as it did before. This is because, leaving the prescribed medicine before time had given the remaining bacterial cells to generate resistance to the drug in the body.


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Growing up the daughter of Chinese immigrants to the U.S., a core part of my identity was as a "second generation" Chinese American. I was therefore more than surprised one day, while conversing with a fellow daughter of Chinese immigrants, to learn that she saw herself as "first generation" Chinese American. Wha? "No," I said, our parents are "first generation," therefore we are "second." "No," she countered," we are the first generation born here, therefore we are "first." "Then what are our parents," I asked, "P0?" (We were in high school genetics class at the time, hence the genetics terminology.) Since then I've learned that there is a lot of confusion/disagreement around the labels, so nowadays when people ask, I just say "I am the daughter of Chinese immigrants."
The reason why I'm now thinking about such labels again is because of "generation 1.5." I had described to a friend the challenges in my quest to find my spiritual roots. The Buddhist and Taoist temples that cater to Chinese immigrants are baffling in that I don't speak Chinese fluently in the first place and often times they don't speak my family's dialect anyway. In contrast, the Western Buddhist groups are unsatisfying, often stripped of any of the cultural practices that I'm seeking to rediscover. I'm hoping that there are other Asian Americans who are similarly seeking, but afraid that maybe they don't exist. Immigrants like my parents do not need their cultural practices explained like I do, whereas often times American-born Chinese aren't interested in what Grandma used to do, looking more to assimilate into Euro-dominated U.S. culture. (That used to be me.) My friend, known for her ability to cut to the heart of the matter, said, "You're looking for a very specific group of people; you're looking for generation 1.5."
Generation 1.5. I'd never heard the term before but immediately it sounded right - the generation that is "too American" to be fully Asian and "too Asian" to be fully American. So I googled "generation 1.5" and found that 1) I was right about being "second generation;" but 2) wrong about what "generation 1.5" meant. It actually refers specifically to immigrants who come over at a young age. But in spirit, generation 1.5 is exactly what I'm looking for:
"Many 1.5 generation individuals are bi-cultural, combining both cultures - culture from the country of origin with the culture of the new country."
To varying extents, this applies to generations 1.0 and 2.0 as well. My dad, having lived now many more years in the U.S. than in China, is more "American" than even he realizes. And I, despite having tried to reject the culture of my ancestors as a kid, nonetheless picked up Chinese ways whether I wanted to or not. We are all, to varying extents, combining both cultures to make something that encompasses all of our experiences, without having to choose/reject one of the two. Generation 1.5.
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Percutaneous Left Atrial Appendage Transcatheter Occlusion (PLAATO System) to Prevent Stroke in High-Risk Patients With Non-Rheumatic Atrial FibrillationResults From the International Multi-Center Feasibility Trials
Author + information
- Received October 5, 2004
- Revision received March 11, 2005
- Accepted March 15, 2005
- Published online July 5, 2005.
Author Information
- Stefan H. Ostermayer, MD⁎,
- Mark Reisman, MD, FACC†,
- Paul H. Kramer, MD, FACC‡,
- Ray V. Matthews, MD, FACC§,
- William A. Gray, MD, FACC†,
- Peter C. Block, MD, FACC∥,
- Heyder Omran, MD¶,
- Antonio L. Bartorelli, MD, FACC#,
- Paolo Della Bella, MD#,
- Carlo Di Mario, MD, FACC⁎⁎,
- Carlo Pappone, MD††,
- Paul N. Casale, MD, FACC‡‡,
- Jeffrey W. Moses, MD, FACC§§,
- Athena Poppas, MD, FACC∥∥,
- David O. Williams, MD, FACC∥∥,
- Bernhard Meier, MD, FACC¶¶,
- Allan Skanes, MD##,
- Paul S. Teirstein, MD, FACC⁎⁎⁎,
- Michael D. Lesh, MD†††,
- Toshiko Nakai, MD†††,
- Yves Bayard⁎,
- Kai Billinger, MD⁎,
- Thomas Trepels, MD⁎,
- Ulrike Krumsdorf, MD⁎ and
- Horst Sievert, MD, FACC⁎,⁎ (horstsievertmd{at}aol.com)
- ↵⁎Reprint requests and correspondence:
Dr. Horst Sievert, CardioVascular Center Frankfurt, Seckbacher Landstrasse 65, 60389 Frankfurt, Germany
Objectives These studies were conducted to evaluate the feasibility of percutaneous left atrial appendage (LAA) occlusion using the PLAATO system (ev3 Inc., Plymouth, Minnesota).
Background Patients with atrial fibrillation (AF) have a five-fold increased risk for stroke. Other studies have shown that more than 90% of atrial thrombi in patients with non-rheumatic AF originate in the LAA. Transvenous closure of the LAA is a new approach in preventing embolism in these patients.
Methods Within two prospective, multi-center trials, LAA occlusion was attempted in 111 patients (age 71 ± 9 years). All patients had a contraindication for anticoagulation therapy and at least one additional risk factor for stroke. The primary end point was incidence of major adverse events (MAEs), a composite of stroke, cardiac or neurological death, myocardial infarction, and requirement for procedure-related cardiovascular surgery within the first month.
Results Implantation was successful in 108 of 111 patients (97.3%, 95% confidence interval [CI] 92.3% to 99.4%) who underwent 113 procedures. One patient (0.9%, 95% CI 0.02% to 4.9%) experienced two MAEs within the first 30 days: need for cardiovascular surgery and in-hospital neurological death. Three other patients underwent in-hospital pericardiocentesis due to a hemopericardium. Average follow-up was 9.8 months. Two patients experienced stroke. No migration or mobile thrombus was noted on transesophageal echocardiogram at one and six months after device implantation.
Conclusions Closing the LAA using the PLAATO system is feasible and can be performed at acceptable risk. It may become an alternative in patients with AF and a contraindication for lifelong anticoagulation treatment.
Atrial fibrillation (AF) is responsible for more than 15% of all strokes (1–3). Besides irregular heart rate and possible lowered endurance, AF leads to insufficient contraction of the left atrium. Stagnation of blood flow within the left atrium leads to hypercoagulability and thus to an increased risk for thrombus formation (4). Several surgical, echocardiographic, and autopsy studies have shown that more than 90% of all thrombi in patients with non-rheumatic AF forming in the left atrium originate in the left atrial appendage (LAA) (5–7). Therefore, occluding the LAA would seem to be a logical approach to preventing thrombus formation and subsequent cardioembolic events in these patients.
A new device has been designed and developed that allows percutaneous LAA transcatheter occlusion (PLAATO System, ev3 Inc., Plymouth, Minnesota) via a trans-septal approach. It has been shown to be safe and effective in occluding the LAA in animal experiments (8).
Two concurrent feasibility studies were conducted, one in Europe and the other in North America. The purpose of these studies was to evaluate the feasibility, safety, and performance of the PLAATO system for LAA occlusion in patients with non-rheumatic AF who were at high risk for ischemic stroke and not candidates for long-term anticoagulation with warfarin.
A small subset of this patient population has been previously reported (9,10).
Study design
These were prospective, non-randomized, multi-center studies. Enrollment started in August 2001 and finished in November 2003.
The primary study end point was the occurrence of major adverse events (MAEs) within one month of the index procedure; MAEs were defined as new major or minor stroke, cardiac or neurological death, myocardial infarction, or requirement for cardiovascular surgery related to the PLAATO procedure.
The secondary end points were to assess the ability of the PLAATO system to occlude the LAA and avoid MAEs during the initial hospitalization as well as MAEs and formation of mobile left atrial thrombus within six months of the procedure.
There also were two device performance end points, including: 1) implantation success, defined as successful delivery and deployment of the PLAATO implant into the LAA and the absence of MAEs within one month of the index procedure; and 2) treatment success, defined as successful delivery and deployment of the PLAATO implant into the LAA and LAA occlusion, as visualized by the investigator with angiography, immediately after placement of the implant.
Serious adverse events (SAEs) were defined as any events that were fatal or life threatening, resulted in persistent or significant disability, required surgical intervention or intensive care unit treatment to prevent permanent impairment or damage, or resulted in re-admission or prolongation of hospitalization.
The LAA occlusion was attempted in 111 patients with non-rheumatic AF of at least three months' duration.
None of them were candidates for anticoagulation therapy, defined as having a contraindication to warfarin on the basis of the warfarin product label.
To be eligible, the patients were required to have a history of transient ischemic attack (TIA) or stroke or at least one (in Europe) or two (in North America) of the following risk factors that put them at high risk for thromboembolic events: presence of congestive heart failure or a left ventricular ejection fraction (LVEF) <40%; a history of systolic hypertension >160 mm Hg; diabetes; age ≥65 years; history of myocardial infarction or known coronary stenosis ≥50%; and moderate or dense spontaneous echocardiographic contrast or blood flow velocity ≤20 cm/s within the LAA.
Key criteria for exclusion were thrombus formation in the left atrium or LAA as well as complex aortic plaque, mitral or aortic stenosis or regurgitation, left atrial diameter >6.5 cm, acute myocardial infarction or unstable angina, and recent stroke (<2 months) as well as symptomatic carotid disease. Patient characteristics at baseline are summarized in Tables 1and 2.
Device and implantation technique
The PLAATO device consists of a self-expanding nitinol cage (range of diameter 15 to 32 mm) covered with expanded polytetrafluoroethylene in order to close off blood flow into the remaining part of the LAA. Three rows of anchors along the struts help stabilize the occluder in the appendage.
All patients received aspirin (300 to 325 mg) twice a day and clopidogrel (75 mg) twice a day 48 h before the procedure as well as antibiotic therapy 1 h before the intervention. After venous and trans-septal puncture, the device was delivered under transesophageal echocardiogram (TEE) and fluoroscopic guidance through a specially designed 12-F trans-septal sheath into the LAA. Heparin was administered in order to keep the activated clotting time above 250 s. The initial device chosen was 20% to 50% larger than the ostium of the LAA measured by angiography and TEE. Both distal (through a special lumen in the device) and proximal (through the distal sheath in the left atrium) dye injections as well as TEE imaging assessed the adequacy of occlusion of the LAA. If an inadequate seal or sub-optimal position of the device was identified, the device was collapsed and re-positioned or exchanged for a device of different size while trans-septal access was maintained.
The degree of sealing after device release was assessed by proximal dye flow and subdivided into four categories: well-defined flow of dye completely filling the appendage (grade 1, "severe leak"); filling two-thirds (grade 2, "moderate leak"); filling one-third (grade 3, "mild leak"); and barely detectable or no detectable blush of dye flowing into the appendage (grade 4, "trace leak" to "absent leak"). The LAA occlusion was defined as a leak of grade 3 or 4. The present study was the first to use the aforementioned angiographic grading to evaluate LAA occlusion. Additionally, transesophageal Doppler color flow was assessed and graded on a five-point scale: multiple jets of free flow (grade 1, "severe leak"); >3 mm diameter jet (grade 2, "moderate leak"); 1 to 3 mm diameter jet (grade 3, "mild leak"); <1 mm diameter jet (grade 4, "trace leak"); no jet (grade 5, "absent leak"). Successful LAA occlusion was defined as a grade of 3 or higher.
After LAA closure, patients were placed on aspirin (300 to 325 mg/day) indefinitely. In North America, clopidogrel (75 mg/day) was prescribed for four to six weeks as well as sub-acute endocarditis prophylaxis for the following six months because of a possible increased risk for infective endocarditis (11). In the European protocol, clopidogrel and prophylactic antibiotic therapy were left to the investigators' discretion. Patients were followed with chest X-ray, transthoracic echocardiography, and clinical examinations after procedure, at 1 week (in Europe), 1 month, 3 months (in North America), 6 months, and 12 months.
In Europe, a TEE was obtained in all patients at one month. The first 20 patients enrolled in North America received a TEE after one month and after six months as well. Transesophageal echocardiogram also was performed at other times at the discretion of the investigator, if clinically indicated. All echocardiograms were evaluated by a core-laboratory.
Statistical analysis
Analyses were conducted on an intent-to-treat basis. Continuous variables are summarized by mean, standard deviation, and minimum and maximum values. Estimates for frequency of occurrence of events are expressed as percentages or rates with 95% confidence intervals (CIs).
Subjects' written informed consent was obtained, and the procedures were performed in accordance with the ethical standards of the responsible committee and with the Helsinki Declaration of 1975, revised in 1983.
Percutaneous LAA occlusion was successful in 108 of 111 patients (97.3%, 95% CI 92.3% to 99.4%). Three patients did not receive a PLAATO device because of the presence of a left atrial thrombus at the time of procedure (n = 1), because of vessel perforation of the right femoral artery during the attempt to access the right femoral vein (n = 1), and because of a cardiac tamponade after trans-septal puncture (n = 1). The last-mentioned patient underwent pericardiocentesis, median sternotomy, and ligation of the LAA 4 h after the index procedure. During hospitalization the patient developed right leg deep vein thrombosis and died at 27 days after the procedure owing to probable cerebral hemorrhage after anticoagulation had been instituted.
The average LAA orifice diameter was 22 ± 4 mm, and the median implant size was 29 mm. Two patients received an 18-mm device; 1 received a 20-mm; 7 received a 23-mm; 15 received a 26-mm; 33 received a 29-mm; and 50 received a 32-mm occluder.
Fifty-five procedures (48.7%) were performed with local anesthesia, and 58 (51.3%) were performed under general anesthesia. The average procedure time was 68 ± 28 min. The average fluoroscopy time was 18 ± 9 min.
Of the 108 patients in which device implantation was successful, 100 (92.6%) received aspirin and 82 (75.9%) received clopidogrel after the procedure.
Duration of follow-up
All of the 108 patients completed their one-month follow-up; 97 (89.8%), their six-month follow-up; and 74 (68.5%), their one-year visit. One patient was lost to follow-up. The average follow-up was 9.8 months, a total of 90.7 documented implant years.
Primary study end points
Of the 111 enrolled patients, 1 patient (0.9%, 95% CI 0.02% to 4.9%) experienced two MAEs within the first 30 days after procedure: need for emergent cardiovascular surgery owing to cardiac tamponade, and neurological death in-hospital as previously described.
Secondary study end points
By six months after the procedure, the rate of patients that experienced no MAEs and/or mobile left atrial thrombus was 97.9% (95% CI 92.2% to 99.8%) on the basis of 95 of 97 patients with six-month follow-up. Two patients did not meet this end point: again, the aforementioned patient with two MAEs during the index hospitalization, and one patient who experienced an ischemic stroke 173 days after procedure.
Device performance end points
Implantation and treatment success were achieved in 108 of 113 procedures (95.6%, 95% CI 90.0% to 98.6%) performed in 111 patients (97.3%, 95% CI 92.3% to 99.4%). Complete recapture and retrieval was successful whenever necessary. Of the 108 implanted devices, 94 (87.0%) showed "trace leak" to "absent leak" after LAA occlusion; 14 patients (13.0%) showed "mild leak."
Echocardiographic results
Immediately after the procedure, 86 of 88 patients (97.7%, 95% CI 92.0% to 99.7%) with assessable TEE showed successful occlusion of their appendage. At one month, 60 of 60 patients (100%) met this criterion (grade 3: 8 patients [13.3%]; grade 4: 31 patients [51.7%]; grade 5: 21 patients [35.0%]). At six months, 49 of 50 patients (98.0%, 95% CI 89.4% to 100%) showed successful LAA occlusion (grade 2: 1 patient [2.0%]; grade 3: 5 patients [10.0%]; grade 4: 27 patients [54.0%]; grade 5: 17 patients [34.0%]). In one patient, TEE revealed a laminar layer along the superior edge of the occluder at the six-month follow-up. With continuing administration of aspirin and clopidogrel this laminar growth resolved over the following six months, showing no remaining material in the 12-month TEE. Echocardiographic examinations showed no mobile thrombus and no disruption of mitral valve function or pulmonary vein inflow in any patient. The echocardiographic results matched the outcome of chest X-ray in excluding device migration or dislodgement from the LAA. The concurrence of transesophageal Doppler color flow and angiography regarding evaluation of LAA occlusion is presented in Table 3.
Adverse events
There were seven MAEs in five patients (Table 4).A total of nine procedure-related SAEs occurred in seven patients. None of the SAEs were adjudicated to be device-related. Procedure-related SAEs included pleural effusion (n = 1) and dyspnea requiring reintubation (n = 1) in one patient, pericardial effusion in two patients (n = 2), and cardiac tamponade in two patients (n = 2). In three of them, pericardiocentesis was performed. One patient also developed a left-sided hemothorax (n = 1) that was noted on the first day after the procedure and was treated by thoracocentesis. One patient experienced right leg deep vein thrombosis (n = 1), and another patient developed brachial plexus palsy (n = 1).
Incidence of stroke and TIA
Of the 111 enrolled patients, 2 (1.8%, 95% CI 0.2% to 6.4%) experienced a stroke 173 and 215 days after the implant procedure. In both patients, TEE performed at the one- and six-month follow-up showed the device in stable position with no thrombogenic layer on the device surface. Doppler color flow at six months showed "trace leak" and "absent leak" in these two patients. Three TIAs occurred in two patients. The observed annual stroke rate was 2.2% (two events during 90.7 documented implant years).
There were six deaths in 111 patients (5.4%). None were adjudicated as device- or procedure-related. The causes of death included cardiac or neurological death (n = 4), secondary complications after gastrointestinal bleeding (n = 1), and an incarcerated hernia (n = 1).
Atrial fibrillation, whether intermittent or sustained, increases the risk for cardioembolic events leading to an overall annual stroke rate of 4.5%/year (12–14). Anticoagulation is highly effective in preventing embolic events in these patients. With a risk reduction of almost 70%, it is superior to aspirin and aspirin plus low-intensity, fixed-dose warfarin treatment (13,15,16). Moreover, the use of warfarin has a narrow therapeutic range. Restrictions in everyday life, pharmacological interactions, and the potential risk of major hemorrhage limit this method of treatment (15,17). These concerns lead to an extensive anticoagulation under-use in general clinical practice (18,19). Furthermore, the benefit of anticoagulation as compared with aspirin treatment is more substantial in patients who are at higher risk for stroke (15,16). Yet these patients are more likely to have relative or absolute contraindications to warfarin treatment.
Percutaneous LAA occlusion is an improved method of a known approach (7,20,21), excluding the LAA from blood flow and thus preventing thrombus formation and subsequent thromboembolic complications. The advantages of this technique include a less invasive procedure, a faster recovery as compared with surgical ligation, and the reduced risk of potential bleeding owing to the absence of long-term anticoagulation therapy.
In our cohort of 111 patients, device implantation was successful in all but 3 patients. Five patients (4.5%) experienced pericardial effusions or hemopericardia that were without sequelae in four patients. In two of the four patients that required pericardiocentesis, however, this incidence occurred due to catheter manipulation during the attempt to access the LAA after trans-septal puncture. They were the first treated patients at a new site. It can be assumed that this number will decrease with increased experience with this new technique.
Five patients experienced MAEs during follow-up (5.5%/year). In the Second Copenhagen Atrial Fibrillation, Aspirin and Anticoagulation Study (22), the risk of stroke, myocardial infarction, and vascular death in patients with AF receiving only aspirin therapy was 4.7%/year (intention-to-treat analysis).
Although the intention of closing the LAA is stroke prevention, the primary aim of this study was to show that LAA occlusion using the new PLAATO device is feasible and can be performed at acceptable risk. In order to make a more definitive statement on reduction of stroke, longer follow-up is needed. As of December 2003, the annual stroke rate of the 108 patients that underwent successful occlusion of their LAA was 2.2%. The cause of stroke in these patients remained uncertain. Transesophageal echocardiogram performed shortly before and after these events showed sufficient occlusion of the LAA with no thrombus formation on the device surface. This would seem to suggest a non-cardioembolic origin and, more importantly, shows that LAA occlusion cannot protect from all ischemic events. On the basis of the patients' CHADS2score (an acronym for congestive heart failure, hypertension, age >75 years, diabetes mellitus, and stroke or transient ischemic attack) (2.5 points) (23), the estimated annual stroke rate for this patient population was 6.3%, assuming they were taking aspirin; this means the relative stroke reduction was 65%. The expected stroke rate may be even higher, since the CHADS2index does not take echocardiographic results such as dense spontaneous echo contrast, a powerful stroke predictor (24), into its calculation.
Study limitations
This was a non-randomized study with a relatively selected patient population. Calculating their stroke risk by using the CHADS2score may only give an idea of what the expected risk for stroke in these patients may be. Furthermore, the follow-up period of the present study was limited to a maximum of 17 months after device implantation. Further studies are necessary to evaluate the performance of the PLAATO device regarding stroke prevention and the long-term tolerance of the device. Further limitations include the limited numbers of assessable TEEs during follow-up.
The results of the present study show that percutaneous LAA occlusion using the new PLAATO system can be performed at acceptable risk. Because it is less invasive, this technique is more practical for a large number of patients compared with surgical closure. Longer-term studies are needed to confirm long-term safety of the device and a reduction in thromboembolic events. This technique may become an alternative therapeutic strategy for patients with AF who are at increased risk for ischemic stroke and, therefore, should receive anticoagulation therapy, but have a contraindication for long-term warfarin treatment.
The authors greatly appreciate the assistance of Franziska Buescheck and Madlen Reschke of the CardioVascular Center Frankfurt, as well as Becky Rorke, Kristine Zurowski, MA, and Linda Johnson, PhD, of ev3.
Investigators (number of patients).Germany: H. Omran (n = 9), H. Sievert (n = 27); Italy: A. Bartorelli/Paolo Della Bella (n = 6), C. Di Mario/C. Pappone (n = 4); Switzerland: B. Meier (n = 1); Canada: A. Skanes (n = 1); United States: P. Block (n = 12), P. Casale (n = 2), W. Gray/M. Reisman (n = 14), P. Kramer (n = 15), R. Matthews (n = 15), J. Moses (n = 2), P. Teirstein (n = 1), D. Williams (n = 2).
This research was supported by ev3 Inc., Plymouth, Minnesota. Dr Lesh is the inventor of the PLAATO device; he was founder, CEO, and a shareholder of APPRIVA Medical, the company that was taken over by ev3.
- Abbreviations and Acronyms
- atrial fibrillation
- confidence interval
- left atrial appendage
- left ventricular ejection fraction
- major adverse event
- serious adverse event
- transesophageal echocardiogram
- transient ischemic attack
- Received October 5, 2004.
- Revision received March 11, 2005.
- Accepted March 15, 2005.
- American College of Cardiology Foundation
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Songbird Rose Liu has announced that she will be releasing her debut album in October this year.
Coming from an untrained background, she rose up the ranks to clinch second place in Taiwanese televised singing reality show "Super Star Avenue" , and further rose in the public eye when she came third runner-up from Na Ying's team on the Chinese reality singing competition "Voice of China".
It has been seven years since her debut, with Rose going through many periods of uncertainty in her journey, such as working as an independent artist without a record label for several years, before finally re-signing and going through seven levels of gruelling auditions to make it onto "The Voice Of China".
Expressing her excitement at finally being able to release her own album, Liu took to Facebook to share her experience doing her first photo shoot for the album, saying that after she had gone through all the preparations for the shoot, she burst into tears upon standing in front of the camera, as she was so moved by the effort all her team had put into allowing this dream of hers to come true!
Boss and artiste Matilda Tao also surprised Liu by livestreaming her recording session, giving fans a sneak peek into her latest song "Yet I still think of you". Listen to it below! Oh, and once again, congratulations Rose!
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December 2019


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I asked one of my past clients to share her love story and tell us a little bit about why she did a boudoir session with me.
Here's what Chelsea had to say…
My Love Story
Tim and I had been friends for years. I started following the band that he was in about five years ago. One night, after a show, we sat around a campfire drinking and talking all night, and after that, we were very good friends.
We were the "text every day, banter and send movie quotes to each other" type of friends. He was very easy to talk to and I knew I could tell him anything.
A few years later he got engaged. I had previously had feelings for Tim, but decided that it was best I moved on and about six months later, I was also engaged.
Three weeks before Tim's wedding he called it off. I met him down at the park some time after, and we sat with our feet in the water, talked, and drank wine.
A few nights later he sent me lyrics and music to a song he had been working on. It was called "Barefoot Love Song."
As I listened to him sing about drinking wine while having your feet in the water, and how he didn't want to say goodbye… I realized that he was talking about us.
At that moment, I realized that he was in love with me. A short time later, my engagement was also called off due to various reasons.
A month or so later, Tim and I decided to start dating. We decided we would take it slow. Four months later we were living together, and two months after that we were engaged.
We will be married in October of this year, 2017. Tim tells me he knew the whole time that I was the one he was supposed to be with, and I think I knew that too, but we were both ready to settle. Settle for what wasn't meant to be.
Now, almost a year to the day that we got engaged, I couldn't be happier. Our relationship is so easy, and there is so much love between the two of us. We disagree and argue like all couples, but there is no doubt in my mind that he's the reason all my other relationships didn't work. He is my road to forever.
Why I Did A Boudoir Session
I had thought about this many times, and had also talked myself out of it many times. I didn't have the money, or the time, or I wanted to lose weight, or a variety of other reasons.
After about six months, I decided I was going to do it. I wanted to surprise Tim with the pictures. I'm not very confident about my body, and I can be very insecure.
But Tim makes me feel beautiful and sexy. So, I decided that if I hated the pictures, I would never show Tim and just count it as a loss.
I had a blast shooting with Molly and would recommend this experience to any woman. I couldn't believe how comfortable I felt half naked in front of someone I just met, much less in front of a camera half naked!
It was fun, and I loved every minute of it. Then, Molly showed me the pictures (before being edited), and I couldn't believe how good they were!
It wasn't that I didn't think Molly was a great photographer, but I couldn't believe how much I loved myself in those pictures. We couldn't decide which ones to choose! Here I am, thinking I'm going to hate all of them, and now I can't decide which ones to delete!
We finally worked it down to 23, and I left feeling great. I had confidence and felt beautiful.
So, I would tell anyone that has thought about doing a shoot, or even ones who haven't thought about it… try it. It's almost like an adrenaline rush when you see those pictures of yourself. I can't wait to show Tim!


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Sign up for email updates from McLeod County Agricultural Association
Up to $2,000 CASH and a GRAND PRIZE OF $5,000 CASH will be given away at the 2019 McLeod County Fair!
Drawing Details:
With each paid gate admission, you receive a double ticket. That ticket will be your entry for the nightly cash awards and qualifier drawing for the grand prize cash drawing for $5,000. To be a winner, you must place half of the ticket into the ticket wheel located near the large east door of the commercial exhibit building.
How the Drawing Works:
Best of luck to all!


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Our Work >
The Homesteader's Finest
The Homesteader's Finest Logo
This startup brand had been selling with DIY labels that weren't performing well, but the product is simply amazing. They needed a logo and packaging design that represented the quality and taste of the product inside. We developed this brand logo mark for them that embodies their homegrown roots yet with the sophistication of their tantalizing gourmet and innovative products. View all The Homesteader's Finest>


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20th April 2018
In 1984 Sir Stelios Haji-Ioannou graduated from Doukas High School in Athens, Greece before moving to study at the London School of Economics. Now the easyJet founder has given back €500k to fund three scholarships at the Doukas school over five years - (starting from 2015) in order to help underprivileged children from Athens (Stelios' birthplace) to get a better education.
As at 15 February 2018Sir Stelios attended today the International Philanthropy Summit in Monaco which took place at the Auditorium Rainier III. Sir Stelios participated in the panel discussion "How Celebrities & Luxury Brands Work to Save Natural Resources and Improve the Livelihoods and Education of the Most Vulnerable and Unprotected People? ".At the end he was awarded for his contribution to philanthropy.
as on 30th January 2018easyJet founder and philanthropist, Sir Stelios Haji-Ioannou, has been captured in oil with a specially commissioned painting in London's National Portrait Gallery. Artist Mary Jane Ansell used oil on an aluminium panel to portray Sir Stelios after a short sitting with extensive photographic preparation. This portrait was commissioned by the Gallery's trustees in 2015 in recognition of his contribution to British business and entrepreneurship.
Stelios Haji-Ioannou with the "Food from the heart" proceeds to a direct donation of 100,000 cookie bites to the Mandra - Idylia Municipality in order to support the victims of the recent catastrophic floods in Mandra and Western Attica. The donation will be done through the "Oloi mazi boroume" which has undertaken the initiative of collecting essentials for the region. Distribution has already begun and will take place over a period of 2 months.
Photo Credits: Zoe NorfolkA South London app developer has won the prestigious £30,000 Stelios Award for Disabled Entrepreneurs, run in conjunction with Leonard Cheshire Disability, after creating a video diary app that supports people managing their mental health.
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Issue details
Determination of Co-ordinated Admission Arrangements 2020/21
This report concerns the determination of the statutory scheme and the mandatory timetable for co-ordinating admissions for Lancashire's primary and secondary schools and academies for 2020/21.
This is deemed to be a Key Decision and the provisions of Standing Order C19 have been complied with.
Decision type: Key
Reason Key: Significant effect in 2 or more electoral divisions;
Decision status: Recommendations Approved
Divisions affected: (All Divisions);
Notice of proposed decision first published: 09/01/2019
Anticipated restriction: Part I -
Decision due: 7 Feb 2019 by Cabinet
Lead member: Cabinet Member for Children, Young People and Schools
Contact: Nan Hogg Email: firstname.lastname@example.com Tel: 01772 531540, Debbie Ormerod Email: firstname.lastname@example.com.
Agenda items


text: Cholesterol affects your hearing Levels of cholesterol in the membranes of locks cells in the inner ear can affect your hearing, said a consortium of researchers from Baylor University of Medicine, Rice University and Purdue University in a written report in the print edition of The Journal of Biological Chemistry. Dr. William Brownell, professor of otolaryngology at BCM and his co-workers, said that the quantity of cholesterol in the external hair cell membrane found in the inner ear can affect hearing. Hobbs called recipient of Breakthrough Prize in Life SciencesDeaths from avoidable risk elements: an interview with Dr Ali Mokdad, IHMEResearch identifies liver pathway that contributes to negative effects of high-unwanted fat, high-cholesterol processed foods dietDr.Approaches for Bone Grafting Onlay Graft – This bone grafting method identifies the keeping the grafting material at the top, or on the relative part of the prevailing bone structure. This is generally utilized when the jawbone provides thinned because of long-term tooth reduction. The dental implants could be placed following the graft area has sufficiently healed, with the graft material totally integrated with the jawbone cells. Block Graft – As the true name suggests, a block grafting technique entails the usage of blocks of bone as grafting materials. This block is carefully measured to precisely fit the positioning of the jawbone where implants shall eventually be placed.


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Gamification is exploding onto the scene in many different industries, and we at WunderTRE think it can benefit business owners when it comes to...read more
Gamification is exploding onto the scene in many different industries, and we at WunderTRE think it can benefit business owners when it comes to digital marketing too! Gamification, as I've mentioned in other posts, is the act of applying a video game like experience to real world tasks. In this post, I'm going to talk about 3 facts that support why gamifying digital marketing is a good idea.
An Enjoyable Experience
There's no doubt that a well-designed game can be very enjoyable. Remember when you were a kid and you'd be playing Super Mario 3 and loving every second of it?
We know that Digital Marketing can be a very stressful and grindy situation. One of the main purposes of gamifying something is to bring in the element of excitement and remove the stress of the task. By applying gamification techniques, we at WunderTRE believe the act of digital marketing can be made fun for all involved!
A Sense Of Direction
Every good game has a clearly defined goal. Players know they have to take certain actions in order to reach the goal, and that there are challenges along the way.
When it comes to digital marketing, it can often be difficult to determine what actions to take and what can progress your business forward. It's often that I talk with business owners that feel like the time and money they are spending on digital marketing is leading to nowhere. This is usually because of a lack of direction and understanding of what it takes.
By gamifying digital marketing, we can layout a clear journey with goals and actions to reach those goals. Tying a value to real-world actions and integrating that with a leveling system allows us to know what moves us forward and at what rate. This gives clarity to the process and makes it easy to understand, leading to less frustration and more reaching goals!
Purpose And Meaning
When you play a great game, you feel like your character has a sense of purpose. Maybe it's saving the princess, or maybe it's being the healer on a squad. Whatever the case, great games make you feel a purpose for being there.
Digital marketing can feel like a lot of work with no return (especially at first), which is one reason so many people give up to soon and don't know how to correctly identify the ROI (Return On Investment).
Using gamification, WunderTRE seeks to add purpose behind every digital marketing action. Knowing what you want to accomplish and what the actions values are to get you there are just one extra way we think gamifying is important.
I hope you've enjoyed today's read, while these three points are great, we've seen so many other positive reasons to bring gamification to digital marketing. We feel like we're just scratching the surface!
Do you have any points for or against the gamification of digital marketing? Tell us in the comments below!
Other Posts You Might Like
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Jan 9, 2019
Getting Your Business Ready for 2019
Dec 17, 2018
The Idea Distillery
Oct 15, 2018


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A 20-year-old woman faces criminal charges following her involvement in a serious crash that left a North Carolina motorcyclist dead. The North Carolina Highway Patrol confirmed that the suspect does not appear to have been intoxicated at the time of the fatal motorcycle crash, adding that speed was not a factor in the crash. However, the woman was ultimately found to be responsible for the fatal accident.
North Carolina traffic wrecks can leave motorcyclists with severe and life-threatening injuries, including bone fractures, soft-tissue damage, brain damage and paralysis. These accidents can even lead to death. In many cases, motorcycle crashes are caused by the negligent, aggressive or otherwise wrongful behavior, or other motorists. The families of those who have been killed in traffic accidents may be able to recover damages compensating them their pain and suffering by filing a wrongful death lawsuit. Individuals interested in such a course of action should contact an experienced North Carolina attorney for more information.
Sources with the North Carolina State Highway Patrol say the accident occurred as the victim was traveling northbound on a county road on his motorcycle. As he approached an intersection with NC 43, the suspect reportedly pulled her sedan in front of him in order to continue south on the highway, causing the two vehicles to slam into each other. The impact caused the victim to fly off his motorcycle and onto the roadway. Emergency medical personnel arrived and transported the man to a nearby medical center to receive treatment. He died from his injuries after being admitted. It is not clear whether the victim was wearing a helmet or other protective gear at the time of the accident.
The suspect was not hurt in the crash. Authorities arrested her several days later on charges of misdemeanor death by motor vehicle. She was released from police custody after submitting a written promise to appear at an upcoming hearing.
Source: New Bern Sun Journal, "Woman charged in connection with Sunday's fatal crash on N.C. 43," Jan. 16, 2013