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Have you been enjoying the resurgence of roguelikes and roguelike-likes? Hopefully so, as The Nightmare Cooperative is the latest on the scene and looks to take things in a different direction.
In Lucky Frame's latest game, your goal is to control a team of adventurers as they search dungeons for treasure. Each teammate has their own powers, as well. What really distinguishes this game from others is that when you move one character the rest of the group moves too. The group movement mechanic is a strange strategic twist that might be very fun or frustrating.
The Nightmare Cooperative arrived on Steam with a 10% discount to start. If you buy before July 23 then the game will cost you $8.99.


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Sure we've all studied Geography and could probably name and point to European countries, or find New York, but do you think that's all maps tell us? You will soon realize, that you were never taught the most interesting things…..things that put things into perspective. Each and every one of these maps reveals different fun and interesting facts.
What makes these maps so exceptional is how easy it becomes to conceive graphically presented information. These maps are way better than the ones they taught you in school.

subset: commoncrawl


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Sportsgirl are breaking all the style "rules" this season with a range which they describe as Eclectic Minx. You can show your individualism and mix and match however you like. Now that is fashion I can relate to! Take a look at some ideas, all pieces are currently available in store or online: What do you think? Would you wear any of these styles? Let … [Read more...]
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Spinners by Shane Warne Clothing
If you are after a witty cricket introduction to this story, I'm afraid you are out of luck. I find cricket indredibly boring and the debate in my house usually ends with my screaming "cricket is not a sport, if you can wear a jumper it is more leisure than competition." Maybe un-Australian of me, but cricket is a man's "cough" sport, but that being said if they took a few … [Read more...]
The T-shirt
From Comfortable Undergarment to Pop Culture Status Symbol T-shirts adorn the bodies of everyone from babies to pensioners and never has there been a fashion craze that has influenced so many people. Whilst wearing a t-shirt as an undergarment has been around for centuries, it wasn't brought to the mainstream until WWI when American soldiers noticed that their European … [Read more...]


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Welcome to the Manhunt: The Search for America's Most Gorgeous Male Model guide at TV Tome. Bravo turns the world of modeling on its high-heels by focusing the camera on the ever-neglected world of male fashion models with the first-ever search for the hottest male model. Watch as unsuspecting men are plucked from the streets and invited to participate in a series of challenges to determine who has the looks, style, stamina and charisma to be a male supermodel. Manhunt: The Search for America's Most Gorgeous Male Model will break fashion industry stereotypes as a group of young newcomers compete for the ultimate prize: a $100,000 contract with top international modeling agency, IMG. Changes are coming soon!


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Bighorn River Mid- July Fishing ReportJuly 11, 2014 1:49 pm Leave your thoughts
The river has leveled off at 7,000 cfs and as of now there are no plans to either raise or lower the river in the immediate future. At this flow once again wade fishing opportunity starts to become limited. The good news is that the river is fishing very well. This most recent bump has flushed almost all of the algae down river. The first 10 miles of the river below Afterbay Dam are now moss/algae free.
The nymph fishing has been stellar with worms, sowbugs, caddis pupa and midge larvae. The wire worm, atomic worm, soft hackle ray charles in grey, soft hackle killerbug, black zebra midge and the poodle sniffer have all been taking fish routinely.
With the warmer than normal water temperatures, the Black Caddis hatch has started and has been consistent in the evening on the upper 3. Cdc caddis, bubbleback emerger, palmered caddis and hemingway caddis have all been good. Fishing a size 14 0r 16 hi vis ant is a great point fly when fishing this emergence. The trout will frequently taking the ant also. Quite a few fish last night were chasing pupa to the surface. Trailing a soft hackle pupa behind an adult also works very well. Expect to see this hatch build.
I floated Afterbay to Mallard's yesterday and saw very few PMD's or Yellow Sallies. With water flows being what they are this year, who knows what these emergences will bring to the Bighorn if anything this year. The river below Bighorn Access looks like pea soup – the water is green and there is A LOT floating moss.
Streamer fishing continues to be really good from top to bottom. Olive, white and black streamers all had their moment in the sun yesterday. The morning and the evening continues to produce the best bite, but midday can still be productive when you find the right pattern. Streamers with a slender profile worked best for us. Squiddly, lil kim, t and a bunkers, peanut envy's and meat whistle's have been getting it done. Sinking leaders or sink tip lines are good to have.
Categorised in: Fishing Reports
This post was written by Bighornangler


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Waves of epileptiform activity in neocortex have three phenomenological stages: initiation, propagation, and termination. We use a well studied model of epileptiform activity in vitro to investigate directly the hypothesis that each stage is governed by an independent mechanism within the underlying cortical circuit. Using the partially disinhibited neocortical slice preparation, activity is induced and modulated using neurotransmitter receptor antagonists and is measured using both intracellular recordings and a linear array of extracellular electrodes. We find that initiation depends on both synaptic excitation and inhibition and entails a slow process of recruitment at discrete spatial locations within cortical layer 5 but not layer 2/3. Propagation depends on synaptic excitation but not inhibition and is a fast process that involves neurons across the spatial extent of the slice and in all cortical layers. Termination is modulated by synaptic excitation and inhibition. In space, termination occurs reliably at discrete locations. In time, termination is characterized by a strong depolarizing shift (block) and recovery of neurons in all cortical layers. These results suggest that the phenomenological stages of epileptiform events correspond to distinct mechanistic stages.
- electrical stimulation
- epileptiform
- picrotoxin
- slice
- somatosensory cortex
- synaptic transmission
- activity waves
Epileptiform activity in the disinhibited neocortical slice can be divided into at least three phenomenological stages. Initiation is characterized by the transition from neuronal activity that is sparse, asynchronous, and local, to activity that is dense, synchronous, and outwardly spreading (Traub and Wong, 1982, 1983a). Propagation can be described roughly as a pulse of synchronous activity transmitted from one neuronal population to the next (Chervin et al., 1988; Chagnac-Amitai and Connors, 1989a; Golomb and Amitai, 1997). Termination can be understood, in space, in terms of propagation failure (Bressloff, 2001) and, in time, in terms of secondary activity patterns following in the wake of an initial wave front and ultimately a return to rest (Miles et al., 1984; Traub et al., 1993). A similar progression is observed in activity waves recorded in vivo [e.g., interictal to ictal transitions (Le Van Quyen et al., 2003)] and in vitro using other experimental models (Traub et al., 1993; Gulyas-Kovacs et al., 2002; Dzhala and Staley, 2003).
In a recent theoretical study, Pinto and Ermentrout (2001) applied singular perturbation analysis to investigate a set of equations that describe waves of epileptiform activity in spatially extended synaptic circuits. Inherent to the theoretical method is an implicit assumption that the mechanisms governing each stage of a wave are independent from each of the others so that, at least to a first approximation, they can be analyzed separately (Tyson and Keener, 1988; Jones, 1994; Kevorkian and Cole, 1996). In the laboratory, this assumption leads to a novel perspective for understanding epileptiform activity. Specifically, the phenomena of initiation, propagation, and termination of epileptiform activity involve distinct and independent mechanisms within the underlying cortical circuit.
Motivated by the theoretical strategy, we examined directly the initiation, propagation, and termination of epileptiform activity evoked in disinhibited neocortical slices. Using a linear array of extracellular electrodes, we investigated the transitions from wave initiation, to wave propagation, to wave termination. In addition, we examined the role of excitation and inhibition on the three stages using neurotransmitter receptor antagonists. Finally, we examined the responses of individual neurons during each stage of the wave using intracellular recordings. Our goals were to test the hypothesis that independent processes within the cortical circuit govern each stage and to further elucidate some of the mechanisms underlying each process individually.
Materials and Methods
Cortical slices 400 μm thick were taken from Sprague Dawley rats [postnatal day 25 (P25) to P35] using a mechanical vibratome (World Precision Instruments, Sarasota, FL). Both thalamocortical (TC) (Agmon and Connors, 1991) and across barrel row (BA) (Finnerty et al., 1999) slice angles were used; results from the two slice angles were similar and so the data were combined. Similar to standard coronal slices, both TC and BA slice angles transect all layers of rodent somatosensory cortex but are approximately perpendicular to each other in the tangential plane. Figure 1a shows a schematic of the TC slice. In TC slices, severing the thalamic afferent pathway had no observable effect on activity propagation (data not shown) and so the slice was left intact during subsequent experiments. Slices were maintained in a liquid-gas interface chamber at room temperature for 1 h and then transferred to an interface recording chamber. In both chambers, slices were bathed in artificial CSF (ACSF) containing the following (in mm): 124 NaCl, 3.5 KCl, 1 Na2PO4, 26 NaHCO3, 10 dextrose, 2 CaCl2, and 2 MgSO4 (saturated with 95% O2/5% CO2). All recordings were obtained at 34°C. The ACSF flow rate in the recording chamber was 1 ml/min.
Before data collection, slice viability was tested by recording field potential responses in cortical layer 2/3 in the region of somatosensory cortex with glass micropipettes (0.5–1.0 MΩ) filled with ACSF. Responses were evoked using a bipolar stimulating electrode (Frederick Haer Company, Bowdoinham, ME) positioned in layer 4 vertical to the recording site. Slices were retained for data collection if a square pulse stimulus of 30 μA lasting 200 μs evoked responses of at least 0.8 mV in TC slices or 0.5 mV in BA slices.
The micropipette was then replaced by a linear extracellular recording array constructed specifically for these experiments. The array consisted of 16 Formvar-coated stainless steel microwires (25 μm diameter, <5 MΩ; California Fine Wire, Grover Beach, CA) embedded in an epoxy holding base and spaced 100 μm apart, for a total recording distance of 1.5 mm along cortical layer 2/3; no attempt was made to bend the array to match precisely the curve of the cortex. Signals were alternating current coupled and amplified (50×; MultiChannel Concepts, Scottsdale, AZ) before being digitized at 10 kHz and digitally low-pass filtered at 1 kHz. In later experiments, a bank of 10× secondary amplifiers was also used (World Precision Instruments). Data acquisition and signal analyses were performed using Labview (National Instruments, Austin, TX) with routines written specifically for the task. Figure 1a presents a schematic of the cortical region studied and the position of the recording array.
Intracellular recordings were obtained using sharp glass microelectrodes (70–100 MΩ) filled with 3 m potassium acetate. Neurons were retained for data collection if they had resting potentials more negative than –65 mV, threshold potentials at least 20 mV above rest, and action potential peaks above 0 mV. Recordings were allowed to stabilize for 10 min before data acquisition. All recordings were made in current-clamp mode (Axoclamp 2B; Axon Instruments, Union City, CA). Intracellular recordings were low-pass filtered and digitized at 10 kHz.
Epileptiform activity was elicited by adding 10 μm of the GABAA receptor antagonist picrotoxin (PTX) (Sigma, St. Louis, MO) to the ACSF bathing solution; other concentrations were used as indicated. In some experiments, 6,7-dinitroquinoxaline-2,3-diome (DNQX) (Sigma) was used to block AMPA receptors. All drugs were titrated into the bathing solution at concentrations as indicated. Initial concentrations were washed in for at least 1 h and changes in concentration for at least 0.5 h before data collection. Low initial concentrations (e.g., picrotoxin) were allowed to wash in for at least 2 h or longer as indicated. Drug washouts lasted for 2 h or until evoked responses demonstrated convincingly that slices remained viable.
Epileptiform activity was evoked using a bipolar stimulating electrode positioned typically in layer 4 either vertical to one end of the recording array to examine initiation or at a horizontal distance of several millimeters to examine propagation and termination. In the latter case, the activity profile remained constant regardless of the laminar stimulus position or above-threshold amplitude, consistent with previous studies (Hablitz, 1987; Chervin et al., 1988). Stimuli consisted of a square current pulse, 200 μs long, with amplitudes ranging from 10 to 100 μA, as indicated. Interstimulus intervals were at least 30 s except when indicated.
Measurements of evoked responses were quantified using field potential data from the recording array. Response velocity was quantified in meters per second by dividing the spatial distance between two recording channels by their difference in onset time. The two channels were selected arbitrarily but were at least 0.5 mm apart, were such that changes in onset time were fairly linear between them, and were fixed for a given recording session. Response duration was quantified in milliseconds as the width at half-height of the field potential at one recording channel. The channel was selected arbitrarily but was between the channels used to measure wave speed and was fixed for a given recording session. Response amplitude was quantified in millivolts as the minimum response below baseline at the same channel used to measure duration. The onset time for a given channel was defined as the time when the response first reached 30% of the minimum value for that channel; measurements of onset time taken anywhere from 10 to 90% were approximately the same because of the sharp onset of epileptiform activity compared with the absolute latency (Fig. 1b). A threshold of 30% was chosen arbitrarily to automate the measurement procedure while minimizing interference from background activity during low-amplitude events. Response latency was quantified as the time between the applied stimulus and the earliest onset time in any of the recording channels.
In most cases, the relationship between each measure and changes in drug concentration were assessed using linear regression analysis with repeated measure; p values were used to test the null hypothesis that the slope of the regression line was significantly different from zero. In the few cases when the relationship did not meet the criteria for linearity, ANOVAs were applied to the data grouped by concentration. Post hoc pairwise analyses (Tukey-Kramer) were used to assess the source of any differences between groups. The same results were obtained using either parametric or nonparametric (Kruskal-Wallis) ANOVAs. All statistical analyses were performed on the original data (i.e., not normalized) unless indicated otherwise.
Data display and analyses were performed using routines specifically written for the task in Labview (National Instruments) and Origin 5.0 (Microcal Software, Northampton, MA). Statistical analyses were conducted using Instat 3.06 (GraphPad Software, San Diego, CA). Figures were assembled using Canvas 8.0 (ACD Systems, Victoria, British Columbia, Canada). Field potential data were linearly interpolated between channels to generate pseudocolor graphs. Figure 1, b and c, shows the same field potential data in raw form (Fig. 1b) and as a pseudocolor graph (Fig. 1c), respectively. In some cases, data were cropped to maximum and/or minimum values as indicated to focus the color scale on important features of the response. Data are reported as mean ± SEM except when indicated.
Data were collected from 140 slices obtained from 96 Sprague Dawley rats aged P25–P35.
Wave initiation is an all-or-none event with a sharp threshold. Waves were evoked by applying a brief stimulus near one end of the recording array. Threshold was defined as the stimulus intensity at which waves were evoked on 50% of the trials. In every slice examined, the stimulus window near threshold was narrow in that small changes in intensity (<1 μA) separated stimuli that evoked waves from those that did not. Figure 2a presents data from a typical example; an increase in stimulus intensity of 4 μA was sufficient to increase the probability of evoking a wave from 0.0 to 0.8. Consistent with previous studies (Traub and Wong, 1983a; Chagnac-Amitai and Connors, 1989a; Lee and Hablitz, 1991), waves evoked by both near-threshold (panel 2) and above-threshold (panel 3) stimuli had nearly identical spatial profiles and velocities, but waves evoked using near-threshold stimuli often emerged only after a substantial temporal delay (panel 2). Both of these phenomena are discussed more fully below.
Initiation threshold depends on the strength of both excitatory and inhibitory synaptic transmission. Figure 2b presents summary data averaged from 10 slices in which increasing concentrations of PTX were titrated into the bathing solution; stimulus intensity threshold decreased significantly as GABAA-mediated inhibition was blocked (p = 0.0125). Consistent with previous studies (Chagnac-Amitai and Connors, 1989a), a minimum PTX concentration of 2–3 μm was required before any stimulus intensity could evoke waves; waves could not be induced at lower PTX concentrations (0–2 μm) regardless of stimulus intensity, even when slices were bathed in PTX for up to 4 h (data not shown). Figure 2c presents summary data averaged from seven slices in which increasing concentrations of DNQX were titrated into a bathing solution containing 10 μm PTX; threshold stimulus intensity increased significantly as AMPA-mediated excitation was blocked (p = 0.0001).
At near-threshold intensities, the delay between the time of the applied stimulus and the time of wave onset was variable from trial to trial. Figure 3a presents data from a typical example in which the latency to wave onset varied from <10 ms to more than 100 ms when evoked with a near-threshold stimulus [mean, 39.9 ms; coefficient of variation (CV), 0.43]. When stimulus strength was doubled, the mean latency decreased to 3.9 ms and became much less variable (CV, 0.18). Figure 3b presents data overlaid from five trials taken from the same example; the profile of field potential responses remained the same regardless of latency (Figs. 2a, 4). Figure 3c presents summary data from 12 slices; four slices were bathed in increasing concentrations of PTX, and eight slices were bathed in 10 μm PTX and increasing concentrations of DNQX. There was no change in mean latency with increasing concentrations of PTX or DNQX (PTX, p = 0.4120; DNQX, p = 0.585). The variability (CV) increased slightly with increasing concentrations of DNQX but not with increasing concentrations of PTX (p = 0.1717). The increase in variability with DNQX was not quite significant when the regression analysis was applied to the original data (p = 0.0756) but was significant when the analysis was applied to the transformed (i.e., normalized) data (p = 0.0129).
Approximately one-third of all slices examined displayed reflected waves or other complex activity patterns after the initial wave, consistent with previous studies (Chagnac-Amitai and Connors, 1989a). A handful of those slices also exhibited variable delays or failures from trial to trial at the point of reflection similar to responses evoked using near-threshold stimuli. Figure 3d presents three trials obtained from one such slice illustrating the phenomenon. In the first panel, the wave propagated only part of the way across the slice. In the second and third panels, activity reemerged after a variable delay from the point of failure and propagated in both directions.
Transition from initiation to propagation
In most cases, the velocity and amplitude of evoked waves were independent of the delay to wave onset. Figure 4, a and b, presents velocity and amplitude data, respectively, from 120 waves evoked using near-threshold stimuli in a slice bathed in 10 μm PTX. In this case, wave amplitude did not vary with latency, but wave velocity increased slightly at longer latencies. Figure 4, c and d, presents R2 values and regression line slopes obtained as in Figure 4, a and b, from seven slices each bathed in 10 μm PTX. Measures from at least 100 waves contributed to the line of best fit for each slice. In every case, wave amplitude did not depend on onset latency. Wave velocity changed slightly, increasing with latency in four slices and decreasing in two slices.
The increase in velocity with onset latency in some slices may result from interactions between multiple initiation zones along the extent of the recording array (Tsau et al., 1998; Ma et al., 2004). In a few cases, the existence of such zones was readily apparent. Figure 4, e and f, presents two examples of the phenomenon. In Figure 4e, the earliest time of wave onset occurred either near the point of stimulation or at a point nearly 1 mm distant. The last panel in Figure 4e presents wave onset profiles from multiple trials. The earliest and latest profiles correspond to the waves shown in the first and second panels, respectively. Figure 4, a and b, also presents data from this experiment. In Figure 4f, the earliest time of wave onset occurred with equal regularity at either the point of stimulation or a point 0.8 mm distant. The last panel in Figure 4f presents onset profiles from multiple trials as in Figure 4e. As shown in Figure 4g, the point of initiation depended on the onset delay: waves emerging with short latency initiated near the stimulating electrode; waves emerging with long latency initiated far from the stimulating electrode; and waves emerging with medium latency initiated nearly simultaneously from both locations and resulted in a high-velocity wave. The outlying point in Figure 4c represents data from this example.
Wave velocity and wave amplitude were independent of stimulus intensity so long as the stimulus was above threshold and was applied at some distance from the recording array. Figure 5, a and b, presents data averaged from 70 waves (7 slices, 10 trials each) examining the effect of stimulus intensity on wave velocity and wave amplitude. Changes in intensity resulted in identical waves when the stimulus was applied at least 1 mm away from the end of the recording array (Far). Near the site of initiation, however (Near), stronger stimuli resulted in larger and faster waves. This is most likely attributable to an increase in the breadth and number of neurons, axons, and synapses activated directly by the applied stimulus. As illustrated in Figure 5c, a strong stimulus evoked broader and larger field potentials than a weak stimulus in a slice with normal inhibition. Correspondingly, a strong stimulus evoked larger and faster waves than a weak stimulus when the same slice was disinhibited.
Once a wave is initiated, the velocity and amplitude of wave propagation depends on the strength of synaptic excitation but not inhibition. Figure 6a–c present data averaged from 180 waves taken from 11 slices measuring the velocity, amplitude, and duration of evoked waves as a function of PTX and/or DNQX concentration; 10 trials were taken from each wave, and, in seven slices, leftward and rightward waves were considered separately and the data were combined. PTX was titrated into the bathing solution up to 10 μm, and then DNQX was titrated until propagation was blocked. In a few slices, only DNQX was titrated into a bathing solution initially containing 10 μm PTX. Results were the same using either protocol and so the data were combined. With slices bathed in 10 μm PTX, the average velocity was 0.074 ± .006 m/s, the average amplitude was 0.52 ± 0.08 mV, and the average duration was 36.8 ± 6.92 ms (mean ± SE). Data were normalized to values at 10 μm PTX to facilitate comparisons between slices.
Consistent with previous studies (Golomb and Amitai, 1997), increasing concentrations of DNQX resulted in significant decrease in wave velocity and wave amplitude (velocity, p < 0.0001; amplitude, p = 0.0003). Increasing concentrations of PTX, however, did not significantly change either wave velocity or wave amplitude once threshold levels of disinhibition were achieved (2–3 μm PTX) (velocity, p = 0.7011; amplitude, p = 0.3543) (Fig. 6a,b). Concentrations of PTX up to 50 μm yielded similar results (data not shown).
Wave duration varied nonlinearly with changes in either PTX or DNQX concentration. ANOVAs applied to the original data grouped by concentration suggest no significant difference in wave duration between groups (PTX, p = 0.2732; DNQX, p = 0.7065). Applied to the transformed (i.e., normalized) data, however, the difference between groups was significant (PTX, p = 0.0004; DNQX, p < 0.0001). For the PTX concentrations, post hoc pairwise analysis (Tukey-Kramer) suggests that the difference arises from a significant increase in wave duration from 2.0 to 5.0 μm PTX (p < 0.05) and from 5.0 to 10.0 μm PTX (p < 0.01). For the DNQX concentrations, post hoc analysis suggests that the difference arises from a significant increase in wave duration from 0 to 0.5 μm DNQX (p < 0.01) and from a significant decrease from 0.5 to 1.0 μm DNQX (p < 0.001).
Figure 6d presents a typical example in which increasing concentrations of PTX had little effect on the profile of the initial wave but facilitated secondary activity that followed in the wake of the initial wave; increasing concentrations of DNQX affected both the initial wave and secondary activity.
Single-cell responses during initiation and propagation
Previous studies have suggested that neurons in the deep cortical layers may be responsible for the onset and propagation of synchronous epileptiform events (Gutnick et al., 1982; Connors, 1984; Chagnac-Amitai and Connors, 1989b; Silva et al., 1991) (for review, see Connors and Telfeian, 2000). Here, we examine this hypothesis directly by recording from individual neurons in cortical layers 2/3 and in layer 5 near the zone of wave initiation. We find that neurons in layer 5 but not layer 2/3 are active during the delay preceding wave initiation and that neurons in both layers are active during wave propagation.
During the delay to wave onset (Fig. 2), activity among individual neurons is presumably circulating within the circuit, with additional activity being recruited until the ensemble response reaches a level sufficient to support a propagating wave (Traub and Wong, 1982, 1983). We recorded intracellularly from individual neurons at one end of the electrode array near the point of initiation in slices bathed in 10 μm PTX. Neurons were located in either layer 2/3 or layer 5. A near-threshold stimulus was applied to layer 4 within the same vertical column as schematized in Figure 7. Figure 7b presents example traces from three neurons each from layers 2/3 and five taken from six different experiments; traces are aligned to the time of wave onset in each case. Of the neurons recorded, only neurons in layer 5 generated action potentials during the delay to wave onset (7 of 18; 39%); layer 2/3 neurons exhibited synaptic events (Fig. 7b) but no action potentials (0 of 20; 0%). Figure 7a presents a table summarizing the results. There were no differences in firing properties, input resistance, or the strength of voltage sags between neurons that were active during the delay and those that were not (data not shown). One of the active neurons was also the only intrinsically bursting neuron recorded in the study; the remaining neurons were regular spiking (McCormick et al., 1985). All of the neurons recorded in both layers were active at wave onset. The variable latency to wave onset corresponds to the variable firing patterns of neurons active during the delay. Figure 7c presents overlaid responses from multiple trials of a single layer 5 neuron during the delay to wave onset.
Like initiation, wave termination in space occurs at discrete locations that remain consistent from trial to trial. Figure 8a presents two trials from the same slice in which the wave terminated within the extent of the recording array. On some trials, activity reemerged from the point of failure after a delay and propagated in both directions. Both the location of the discontinuity and the profile of the secondary wave were consistent from trial to trial (data not shown). Additional examples from different experiments are presented in Figures 8b and 3d.
Wave termination, in time, coincided with the end of the initial wave of depolarization in most cases. In approximately one-third of the slices, however, secondary waves or other complex activity patterns followed in the wake of the initial wave. In contrast to the disinhibited hippocampal slice (Miles et al., 1988; Traub et al., 1993), secondary waves were much less robust and more variable from trial to trial than the initial wave. Figure 8, c and d, presents data gathered from two slices that exhibited complex secondary activity patterns. Overlaid field potential data from multiple trials on one electrode illustrates the trial-to-trial variability of secondary activity. An additional example is presented in Figure 9b.
Single-cell responses: termination
Consistent with previous studies (Prince, 1967; Dichter and Spencer, 1969a,b; Matsumoto et al., 1969; Ayala et al., 1970; Gutnick et al., 1982; Hablitz, 1987), termination of the initial wave coincided with neurons entering a state of prolonged depolarization (i.e., depolarization block). Figure 9a presents a typical example from a neuron located in layer 2/3. Activity in individual neurons also reflected secondary activity patterns following in the wake of the initial wave. Figure 9b presents an example from a slice in which both field potential and intracellular recordings from a layer 2/3 neuron displayed complex secondary activity patterns. Neurons in both layers 2/3 and 5 were active during secondary activity.
Three neurons from three different experiments exhibited responses that changed progressively when waves were evoked repetitively. Figure 9, c and d, shows sequential responses from two such neurons during wave propagation evoked at a frequency of 1 Hz. In Figure 9c, the neuron remained in a depolarized state for the extent of the initial wave and then generated a longer series of recovery spikes on successive trials. The field potential response did not reflect the recovery spikes. In Figure 9d, the neuron remained in a depolarized state longer on successive trials and generated approximately the same number of recovery spikes. The field potential displayed low-amplitude, high-frequency activity that lasted for the duration of the blocked state in the neuron on each trial.
Our results support the hypothesis that distinct and independent mechanisms govern the phenomena of initiation, propagation, and termination of epileptiform activity in disinhibited cortical slices. Initiation depends on both synaptic excitation and inhibition. It is a relatively slow and variable process that takes place among the neurons of cortical layer 5 at discrete spatial locations. In contrast, propagation velocity and amplitude depend on synaptic excitation but not inhibition (above a threshold level). Propagation is a relatively fast and reliable process involving neurons throughout the spatial extent of the slice. Termination is modulated by both synaptic excitation and inhibition and is characterized by depolarization block and recovery among neurons in all cortical layers. Like initiation, termination can be a variable process and occurs in space at discrete spatial locations. Termination can also involve secondary activity patterns that propagate in space in a manner similar to the initial wave.
In addition to testing our central hypothesis, our results confirm a number of previously observed phenomena and also present several results not reported previously. Among our more striking novel findings include the subthreshold drift of the point of initiation away from the location of the applied stimulus (Fig. 4), the independence of propagation velocity on the strength of above-threshold disinhibition (Fig. 6), the spiking activity in layer 5 but not 2/3 during wave initiation (Fig. 7), and the variability of ongoing activity relative to the initial wave (Fig. 8).
Data presented in Figures 2 and 7 suggest that wave initiation is an all-or-none event with a narrow stimulus threshold window. During initiation, spiking activity circulates among the neurons of layer 5, but not layer 2/3, until the system either returns to rest or reaches a level of activity sufficient to support a propagating wave. The process is best observed in the slice using a near-threshold stimulus; a strong stimulus will activate a large population of neurons directly, bypassing the subtle recruitment process. A similar process explains the delay preceding wave reflections (Fig. 3) and secondary waves (Fig. 8). We detected no common response features to distinguish neurons that were active during the initiation process from those that were not.
The variable delay to wave onset shown in Figure 2 is consistent with previous results (Miles and Traub, 1987; Chagnac-Amitai and Connors, 1989a; Lee and Hablitz, 1991) and is typical of a dynamic system lingering momentarily near an unstable manifold between two stable states. Here, the stable states are rest and stable propagation (Pinto and Ermentrout, 2001). Van Vreeswijk and Hansel (2001) analyzed theoretically the transition of network activity from dispersed and uncorrelated to synchronous and bursting as the level of inhibition decreases.
The persistent activity among layer 5 neurons observed during the recruitment process (Fig. 7c) is reminiscent of activity "bumps" characteristic of some models of working memory (Wang XJ, 2003). Laing and Chow (2001) analyzed conditions under which such activity can either stabilize to a local activity bump or destabilize into a pair of propagating waves. For the conditions used here, activity always destabilized into a pair of propagating waves. It may be possible, however, to adjust the protocol (by modifying the bathing solution or using a different slice angle, for instance) to facilitate and study stable activity bumps in brain slices.
Similar patterns of recruitment leading to initiation have been observed in both hippocampal slices (Wong and Traub, 1983; Knowles et al., 1987), in the developing retina (Feller et al., 1996), and in computational models of both systems (Traub and Wong, 1983b; Traub et al., 1993; Feller et al., 1997; Butts et al., 1999). Waves in disinhibited hippocampal slices initiate exclusively from the CA2 region (Knowles et al., 1987). Waves in the developing retina initiate from randomly distributed sites (Feller et al., 1997). In all three systems, the process is one of recruitment leading to threshold.
Rather than a series of sequential initiations, wave propagation may be better understood as the transmission of activity along a continuum of neuronal populations (Ermentrout, 1998). Data presented in Figure 6, a and b, suggests that, once threshold is reached, increasing levels of disinhibition have little effect on either wave velocity or amplitude. Similar results have been reported in a study of hippocampal/entorhinal cortical slices (Menendez de la Prida and Pozo, 2002).
There are at least two explanations for this nonintuitive result. First, the level of disinhibition in the slice may be near-maximal at low concentrations of PTX. This seems unlikely, however, because in a study of hypothalamic slices taken from young rats (P1–P14), Huang and Dillon (2002) report the IC50 value for PTX inhibition of GABAA currents as 2.6 ± 0.4 μm. The value decreases linearly to ∼75% block at 10 μm PTX (Huang and Dillon, 2002). Second, the insensitivity of the wave to inhibition might be explained by the same mechanism that accounts for the processing of transient inputs during sensory processing (Pinto et al., 2003). In this scenario, a propagating wave activates local circuitry in the same manner as a synchronous barrage of input arriving from the thalamus. The incoming signal activates both excitatory and inhibitory neurons, with the response of the excitatory neurons increasing exponentially attributable to locally recurrent excitatory connections. The exponential increase in excitation is relayed to the inhibitory neurons, and, as a result, their activity also increases exponentially. In the context of thalamocortical processing, the delay between the arrival of an input signal and the buildup of network inhibition provides a window of opportunity during which thalamic input can evoke a strong excitatory response (Pinto et al., 2003). In the context of epileptiform activity, the same delay allows an activity wave to escape from the local circuit unimpeded by inhibition; given a delay of 5 ms, a wave propagating at 0.1 m/s will have traveled 0.5 mm. One prediction from this scenario is that increased levels of disinhibition should result in waves having longer duration, which, as shown in Figure 5c, is precisely what happens.
Conceivably, termination of the initial wave may simply be attributable to the entry of the neurons into depolarization block, resulting in cessation of synaptic transmission; secondary waves would emerge during the recovery from block and the resumption of firing (Bragin et al., 1997). However, even when the soma is in a blocked state, axon terminals might still be active (Gutnick and Prince, 1972; Noebels and Prince, 1978). Moreover, data presented here and previously in studies by others suggest that wave termination involves intrinsic properties of individual neurons, synaptic interactions, glial cell processes, and other factors influencing neuronal activity. For instance, the dependence of wave duration on inhibition (Fig. 6c) argues for a role of synaptic interactions on wave termination. In a model of the hippocampal network, secondary waves could be simulated only with the inclusion of specific intrinsic properties, such as extended dendrites and voltage-activated calcium currents (Traub et al., 1993). Secondary waves also depend on synaptic interactions because they can be suppressed using NMDA receptor antagonists (Miles et al., 1984; Lee and Hablitz, 1991; Traub et al., 1993; Lopantsev and Avoli, 1998; Telfeian and Connors, 1998; Castro-Alamancas and Rigas, 2002). Using a low [Ca2+] protocol to induce waves in hippocampal slices, Bikson et al. (2003) demonstrated that the duration of epileptiform events does not depend on continued somatic neuronal firing. Interestingly, periods of high activity lead to increased intracellular acidification, and manipulation of intracellular pH can shorten the duration of epileptiform discharges in the hippocampal slice (Xiong et al., 2000), possibly attributable to the closing of gap junctions (Rorig et al., 1996; Jahromi et al., 2002). Glial cells are also partly responsible for the clearance and maintenance of excitatory and inhibitory neurotransmitters from the extracellular space, placing them in a position to influence all stages of wave generation (Duffy and MacVicar, 1999; Kettenmann, 1999; Schousboe, 2003). Clearly, wave termination is a complex process that will require additional study to understand completely.
Our study has focused intentionally on the well studied phenomenon of waves evoked in the disinhibited cortical slice. Clinically, such waves are most comparable with interictal events that precede ictal epileptic activity (Prince and Connors, 1986; Dzhala and Staley, 2003; Le Van Quyen et al., 2003). Additional study is required to determine whether other models of epileptiform activity can be divided similarly into distinct mechanistic phases. We propose, however, that epileptiform activity induced by different protocols, both in vitro and in vivo, can be understood and compared in terms of initiation, propagation, and termination. Although the details may differ, the biophysical mechanisms underlying each stage may be similar and hence comparable across protocols.
The mathematical tool of singular perturbation analysis proceeds by dissecting a dynamic process and analyzing separately its constituent components while still acknowledging the complexity of the whole. Our experimental results suggest that a similar strategy may be useful for understanding epileptiform activity in neocortex. Recognizing and elucidating the specific mechanisms underlying each individual stage could form the basis for both comparing epileptiform activity across protocols and more targeted and focused approaches to controlling or curtailing epilepsy in a clinical setting.
This work supported by National Institutes of Health Grants NS25983 and DA125000 and a fellowship from the Burroughs-Wellcome Foundation. We thank Ed Mullen for his assistance in the design and construction of the electrode recording array.
Correspondence should be addressed to David J. Pinto at his present address: Department of Neurobiology and Anatomy and Department of Biomedical Engineering, University of Rochester School of Medicine, Box 603, 601 Elmwood Avenue, Rochester, NY 14625. E-mail: david_pinto{at}urmc.rochester.edu.
Copyright © 2005 Society for Neuroscience 0270-6474/05/258131-10$15.00/0


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A unique plaster that relieves pain by removing corns and calluses on your feet. Simply apply this product as instructed and feel the world of difference.
This product relieves pain by removing corns and calluses.
Manufactured byGuangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd.Baiyunshan Hejigong Pharmaceutical Factory
Product ofChina
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$5.95 $4.16 $1.79
Did you get stamped at Congaree National Park? The Passport To Your National Parks encourages visitors to explore the more than 400 National Park Service sites across the country and find out what makes each one special. Remember every step on the trails of Congaree with a hiking medallion from the Passport Collection!
Product Details
Average rating:
Congaree Hiking pins., 27th Dec 2018
Reviewer: Gerlinde Higginbotham
I really like this medallion, hiking pins are hard to find sometimes. This is nice because its shape fits my hiking stick perfectly. National Parks are the best and its nice to have something as a memory of the beauty and also to show off where you have been. Especially when the parks are off the well travelled path, like Congaree.


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Humungous boobs encased in a taut, milky most sensible. A brief, ebony miniskirt. Beautiful tights. Now that is what legislation enforcement is all about! Crime charges cross down and shafts cross up when Arianna is ambling the hammer.
"Who has been ultra-kinky?" nursling requests. "You! You sight like a kinky stud! Take your trousers off and embark kneading your spear for me!"
Sure, Officer Arianna. Earlier than we understand it, Arianna has our total consideration and is turning her boobs out of her most sensible, then romping her vagina with a ebony fake penis that would dual for a nightstick. Teenager's were given a gun on her holster and meaty weapons coming out of her torso.
"You might be beneath arrest!"
Thanks, Officer!


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Grade level: 3-8
Equipment: Pinnies, dodgeballs
Game Description: In Fitness Dodgeball, the 'Personal Trainers' (the taggers) will go around trying to throw the ball at the players running around. When hit, the players must perform some action such as pushups, situps, jumping jacks, before getting back into the game. Dodging, running, throwing, rolling, and a variety of exercises makes for an active PE game.
Fitness Dodgeball
Grade level: 3-8


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Project Of The Month November - Twilight Storybox Digi Paper Kit
Create a beautiful project with a difference. The papers used for this project are available on the Twilight Queen Story Boxes cd or there is a Digi Paper Kit available too.
MaterialsMaterals :
Template from CD
3 x A4 Card
Backing Papers
Pyramid Magic Sheet
Basic Equipment
Foam Pads
Knife, ruler, pencil
Score board
Trimmer/Craft Knife
Double sided tape
Sticky pads/Silicone
Score board
Bone folder
What You Need to Do
To start this project go to our Digi Paper Kits section of the website and download your Twilight Storybox for only £1.50!. If your printer will take it print directly onto card, otherwise back onto card now to give support.
Cut along the solid lines and score on the broken.
We will work on the base first.
Make up the base box, making sure the design is on the base.
Next make the top which is a gatefold card with an aperture in the middle. Cut using a craft knife and ruler.
Make up the tray as shown below in fig 4. Attach this inside your base. Make up your pyramid magic, position and attach to the inside of your box. (Top Tip: remember to add your glitter and gems to your topper before attaching to the inside of the box)
Position the gatefold card onto the box making sure you can see your pyramid magic through the aperture attaching with glue.Attach a decorative frame around the aperture from the Embellishments page.
Decorate the front of your card. Finish with gems, glitter and a wrap from the Embellishments page.
Top Tip: As an alternative you could make the front an A5 card instead of a gatefold, then use the page strips and book spine to make it look more like a book.
Reasons to Shop at Debbi Moore?
- Safe Ordering through Sagepay
- Secure Delivery with our trusted couriers
- Guaranteed Quality art and craft products


text: Belgrade Follow30 Favorite0 Trendy!2 1 Coat Zara 2 Sweatshirt Skrabac 3 Jeans Massimo Dutti 4 Handbag Mexx 5 Scarf Terranova Branislava Antović Look: Spa day - Great for casual - 9 March 2016 When you travel you want to be comfortable. Why not feel good and look good at the same time :) Share Tweet Pin it Whatsapp Comments Want to comment on this? Login or Sign Up on Trendtation. Reply


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Cage Fitness Highlight Video
Cardio Kickboxing Highlight Video
Cage Fitness and Cardio Kickboxing in Jackson, New Jersey- "Kick. Punch. Sweat…Fitness for Women and Men."
Cage Fitness is perfect for people who want to tone up, lose weight and get into shape. The class is designed to get maximum results in only 30 minutes, so it is perfect for people who don't have an hour or two to spend in the gym. The workouts are always challenging and therefore never gets boring. Try a Cage Fitness class today and see what all the hype is about. Fill out the form below so we can be in touch,
What is Cage Fitness?
It is a complete workout program that is designed to cater to people at all levels of fitness. Cage Fitness is based on the structure of a championship MMA bout. What this means is that Cage Fitness will give you a total body workout in just 5 – 5 Minutes rounds. There are four key elements that are focused on: Endurance, strength, power and core. This is accomplished through our 5 round fitness system which is broken up into the following categories: Warm Up, Upper Body, Lower Body, Cage Combo round and Core/Cool Down.
The best part about cage Fitness is that an individual can customize their workout by adjusting their intensity level to best suit their personal fitness goals. Each 5 minute round incorporates both aerobic and anaerobic exercises that will help maximize burning fat while also gaining muscle. This system of training allows the participant to burn more calories while increasing ones metabolism.
Who is involved?
Cage Fitness is endorsed and tested by 9 time Welterweight Champion Matt Hughes. The exercises have been created from a mixed martial artist Matt Hughes and Kai Fusser M.S. Kai Fusser has trained elite level athletes such as 10 x LPGA major winner Annika Sorrenstam, NBA Allstar Grant Hill, 3 time X Games gold medal winner Darin Shapiro, Formula One and Indy racing league driver Eddie Cheever and many more.
Do you offer Cardio Kickboxing?
Yes we do and it's INCLUDED with your Cage Fitness membership. In order to add variety and additional training to your workout, we offer cardio kickboxing every other Monday and every Wednesday. Our kickboxing class is taught by certified martial arts instructors so all technique is taught with proper technique and execution. This will allow for safe and realistic training (without a partner) while providing you an amazing full body workout.
Shout Out from Matt Hughes, 9x UFC Welterweight Champ and creator for Cage Fitness!
Frequently Asked Questions
Is there any contact Cage Fitness?
No. There is no contact in Cage Fitness or working with partners. Cage Fitness is a fitness program designed for individuals to work at their own pace. The exercises are safe for women and men.
Is Cage Fitness Martial Arts?
No. Cage Fitness is based on the training methods used by Mixed Martial Arts (MMA) athletes. MMA participants are considered by most to be accomplished athletes who have obtained the highest levels of fitness. We have modified some of their training techniques to create this fitness program. Cage Fitness will get people into the best shape without having to train in MMA. This makes Cage Ftiness not only one of the best workouts one can get, but also challenging and fun.
I have never worked out before…is Cage Fitness for me?
Yes. Unlike an aerobic class or other fitness classes where an instructor is leading a group of people through various exercises at a certain pace, Cage Fitness is broken up into 5 -5 Minute rounds that are made up of times segments within those rounds. An individual can compete with themselves to see how many repetitions of each exercise he/she can do within those segments.
What should I wear to class?
Participants should wear comfortable and loose fitting work out clothes. When signing up one should also purchase bag gloves for hitting the grappling dummy.
How long are the classes?
Cage Fitness was designed to get maximum results in a short amount of time. The class is 30 minutes which consists of 5 – 5 minute rounds with a 1 minute rest in between. This is the same format used in a championship MMA match. This allows an individual to complete a great workout without taking up too much of their day.
Cage Fitness Testimonials
"I really liked it, it was intense and it made me feel good about myself."
- Abigail Lee
"Intense, I worked my cardio hard!"
– Bill Simmons.
"The class was really good. I enjoyed it a lot. It wasn't too long and I got a great workout in. I feel much more tired and sweaty then I did with Cardio Kickboxing."
– Jen Sobin.
"I thought it was awesome."
– Carrieann Domanico
"Incredible! I feel like I worked out every part of my body! I like how intense each round is."
– Suzanne Carbone
"Excellent! I love the intensity and the move at your own pace layout. It's great that you can make the class as intense as you want. I love the Ground and Pound section and lifting and tossing the Cage Bag around, it was an empowering feeling."
– Dan Chandler
"Great workout, the combinations were intense."
– Donna Langel
I am loving cage fitness. Not only am I physically improving, my stress level has declined. This is by fa
r the best gift I have ever given myself. I wish you much success and growth in your path asyou help change lives. Thank you.
Tiffany Stewart
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Killing Life: "Hungry Hearts" deceptively unnerves and hard to shake
Hungry Hearts (2015)
118 min., not rated (equivalent of an R).
Child-rearing drives the horror in "Hungry Hearts," writer-director Saverio Costanzo's deceptively unnerving drama that will keep new mothers on tenterhooks and put vegans on the defensive. It follows in a list of maternity nightmares—1968's "Rosemary's Baby," 2007's "Inside," 2009's "Grace," 2013's "Proxy," 2014's "The Babadook" and a very impressive short film with Gaby Hoffmann called "Lyle"—but the film is absorbing and provocative all on its own with varied performances. A grounded, unconventional horror drama about a parent's love, control and trust, based on Marco Franzoso's novel, "Hungry Hearts" treats motherhood (and fatherhood, too) as not only a gift but a poison. Beginning with an odd meet-cute and celebratory use of Irene Cara's "What a Feeling" at the characters' wedding reception, there is no way of knowing how it will all end up.
Before having a relationship and getting married, New York City engineer Jude (Adam Driver) and Italian embassy worker Mina (Alba Rohrwacher) meet cute as strangers when they both stuck in a Chinese restaurant bathroom. When Mina gets pregnant, the small-framed vegan appears underweight to the doctor. Mina then takes a psychic reading to heart when she is told that her child is an "indigo child." At first, Jude respects his wife's wishes for a natural water birth and her decision to not feed their son meat, until the boy comes down with a fever for two weeks. Having grown overprotective to the point that she doesn't trust medical professionals, Mina has kept their son inside for seven months without anyone monitoring the child's development or consulting their son's meat-free diet. Jude thinks his own wife is being unreasonable and unconsciously starving their son, so he begins taking the child out for walks and entering a church to secretly feed him ham in order to make him grow. From there, Mina's delusions worsen once Jude's estranged mother Anne (Roberta Maxwell) gets involved.
Writer-director Saverio Costanzo values the psychology of his two characters, aiming in on a grey area with equal measures of ambiguity and clarity. In what is essentially a two-characer piece before grandmother Anne enters the picture, Adam Driver and Alba Rohrwacher (2009's "I Am Love") do stunningly exceptional work as Jude and Mina, a married couple who don't see eye to eye with what their child needs. As he has shown outbursts of anger in both HBO's "Girls" and even a little in 2014's "This Is Where I Leave You," Driver holds in his rage for quite a while, walking on egg shells around his wife but still taking charge and doing what he sees as healthy and advantageous for his son. If that means losing Mina's trust in the process, then so be it. If Driver continues to ride the wave of indie cinema, he can fully tap into the gravitas he clearly has in him. Mina isn't exactly sympathetic from the viewer's eye, but Rohrwacher does not make her an evil villain, either. She is a mother bound by her beliefs, or perhaps delusions, clinging to her son to whom she's given life and never letting him out of her sight. Mina keeps having a dream about a deer being shot on the boardwalk of Coney Island, later turning into a counterpoint to Jude's mother's house with a deer head in the living room. Comparisons to Roman Polanski are welcome, but "Hungry Hearts" is chilling without seeming too heightened. There is a subtle use of orchestral strings that never allows Nicola Piovani's score to go hog-wild, "Psycho"-style, and Fabio Cianchetti's grainy digital cinematography uses a fish-eye lens to claustrophobic effect in Jude and Mina's apartment. In being not so easy to shake with plenty to ponder, "Hungry Hearts" is one of the best examples of telling a horror story without sensationalizing it. It's troubling and downright effective.
Grade: B +


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Ex. 1:1 These are the names of the sons of Israel who came to Egypt with Jacob
Names are very useful, they define objects and subjects. They tell us what things are or what they are not. Exodus is the greek name for this book. The Hebrew title of this book is "Names."
These are the names….
Shiprah, Puah, Jocheved, Miriam, Aaron, Moses, Pharaoh, Jethro, Zipporah, and YHWH, the LORD. One by one the writer of Exodus introduces us to each succeeding character. In majestic fashion he unfolds the cast, character by character. The remarkable thing about all these names is that Pharaoh alone is the one name that is not personal. It could roughly be translated as "king" (literally "the great house"). He is only his title his very identity is only what he does.
By introducing all the characters the writer wants to immortalize their deeds and identities. The Pharaoh remains unknown, to this day commentators debate as to whether he was Seti I or Ramses II. We will never know, but we know the bravery of Shiprah and Puah.
Shiprah and Puah were two midwives—not the most particularly most glorious profession in the ancient near east. Nearly 3,300 years later we still tell their story and have no idea who Pharaoh is.
Pharaoah, who struggles to build great treasure cities for himself, remains incognito for eternity, whilst the Shiprah and Puah are sung through the ages.
Tucked into this passage is the secret of these faceless and nameless midwives, "because the midwives feared God, he gave them families."(Ex 1:21) What a telling story. Women who had no name and no future are forever remembered by God and granted families. To not have children was considered the end of your family name. Women who did not have names were relegated to helping other women have children but never have their own.
God miraculously rescues both the children of Israel and the midwives. They get to see their offspring in the land of the living and rejoice. It is the fear of the Lord that assures their name forever. Paul speaks of this fear, "Therefore God has highly exalted him and bestowed on him the name that is above every name,"(Phil 2:9) when he speaks of Jesus choosing to fear God and obey. It is Christ's obedience that guarantees we will never be forgotten.
The Psalmist speaks of this One, True Hero:
Psa. 22:22
I will tell of your name to my brothers;
in the midst of the congregation I will praise you:
23 You who fear the LORD, praise him!
All you offspring of Jacob, glorify him,
and stand in awe of him, all you offspring of Israel!
This post is also available in: Spanish


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Lawyers for the family of a soldier killed when a troop carrier rolled have questioned the driver's account of the crash.
Former soldier Alexander Gall was asked on Friday how he could have been shocked by a sharp bend on the army training course when he'd driven on the same road the day before.
Mr Gall has told a commission of inquiry into the October 2012 incident that killed Sapper Jordan Penpraze, 22, he wasn't speeding at the time.


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Official Positions
Santa Barbara County Republican Central Committee
Position Statements
California Prosperity Agenda
The Santa Barbara County Republican Central Committee has endorsed the California Prosperity Agenda proposed by the Pacific Research Institute for Public Policy (PRI), a California-based organization which champions freedom, opportunity, and personal responsibility for all individuals by advancing free-market policy solutions. The California Prosperity Agenda is a 12-point, multi-year plan that reflects the best thinking of PRI researchers and think tanks nationwide on how to restore freedom and opportunity to Californians.
To read the California Prosperity Agenda, please click here.
Repeal The Gas Tax
The Santa Barbara County Republican Central Committee unanimously endorsed Repeal of the Gas Tax, implemented under Senate Bill 1 which became effective November 1, 2017.
The gasoline excise tax will rise 43 percent, or by 12 cents per gallon, generating an estimated $24.4 billion in revenue. The diesel tax will climb 125 percent, by 20 cents per gallon. This increase would add another $7.3 billion.
The diesel sales tax will rise 5.75 percent and raise $3.5 billion.
A vehicle fee, similar to what owners currently pay the Department of Motor Vehicles annually, will raise $16.3 billion.
Zero-emission vehicles will have to pay a $100 annual fee for road maintenance beginning in 2020.
To read the entire Senate Bill 1 please click here: leginfo.legislature.ca.gov/faces/billNavClient.xhtml?bill_id=201720180SB1
The worsening crisis at the southern border shows that the construction of a physical barrier is necessary.
WHEREAS, the absence of a physical barrier along the southern border enables the widespread trafficking of narcotics, weaponry, enslaved women and children, and other contraband by transnational criminal gangs.
WHEREAS, coyotes (contract smugglers) sexually assault more than one-third of all female migrants on the dangerous journey from Central and South America across the southern border. WHEREAS, illegal aliens have caused grievous bodily harm to American citizens of California residence, including the 2015 home-invasion murder of Santa Barbara County resident Marilyn Pharis (an Air Force Veteran), and the 2018 line-of-duty murder of Cpl. Ronil Singh (a seven-year veteran of the Newman Police Department and naturalized American citizen of Indian origin). WHEREAS, the entry of illegal aliens into the American labor force suppresses wages for low-skilled American workers who cannot compete with the de facto tax-exempt status of undocumented laborers; Bureau of Labor Statistics data indicate that wages for African Americans and Hispanic Americans have proven to be most disaffected.
WHEREAS, border security is not only an imperative feature of any sovereign nation, but also unequivocally required by Article IV, Section 4 of the U.S. Constitution, as follows. "The United States shall guarantee to every State in this Union a Republican Form of Government, and shall protect each of them against invasion…"
NOW, THEREFORE, BE IT RESOLVED that the Santa Barbara County Republican Party reaffirms its definitive support for the construction of a border wall amid the ongoing government shutdown. The National Border Patrol Council has determined that the absence of a physical barrier on the southern border has resulted in the aforementioned concerns. If Democratic Party leadership refuses to negotiate in good faith, President Trump must weigh these exigent circumstances with his executive authority to declare a National Emergency and, if necessary, allocate defense funds for the construction of a physical barrier as part of a comprehensive border security strategy.


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About National Aluminium Company Limited – NALCO Recruitment
NALCO Recruitment – National Aluminium Company Limited, well known as NALCO, started in 1981. It has units at places like Angul and Damanjodi in Odisha. It was started as a public sector enterprise of the Ministry of Mines, Government of India in 1981. It is Asia's largest, and the 6th largest, integrated aluminium complex, encompassing bauxite mining, alumina refining, aluminium smelting and casting, power generation, rail and port operations.
NALCO Junior Manager Recruitment 2018 – (01 Vacancies) – (11 October 2018)
|Vacancy Name:
Junior Manager
|No. of Vacancies:
01 Vacancies
|Pay Scale:
|60000 – 180000/-
|Eligibility / Qualification:
|Degree in any discipline.
Click here for NALCO Junior Manager Recruitment 2018 Details.
NALCO Assistant General Manager Recruitment 2018 – (01 Vacancies) – (11 October 2018)
|Vacancy Name:
Assistant General Manager
|No. of Vacancies:
01 Vacancies
|Pay Scale:
|120000 – 280000/-
|Eligibility / Qualification:
|Degree in Engg or any discipline and Should have work experience in the relevant field.
Click here for NALCO Assistant General Manager Recruitment 2018 Details.
What will you get on India Exam Result about NALCO Recruitment?
We provide latest NALCO Vacancy updates. With our updates, you will get recruitment notice, admit cards, result updates, answer key, exam syllabus and exam date reminder of "National Aluminium Company Limited". On our website www.indiaexamresult.in, we provide you the possibility for looking NALCO Recruitment by your academic qualification. You can search NALCO Employments by cities and states wise.
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In order to allow you on perfect time and perfect job announcements about all National Aluminium Company Limited admit card download, NALCO Result, recruitment updates, NALCO answer key. We have a best practice to keep eye on all prime most newspapers in India for NALCO Recruitment as well as employment news & Rojgar Samachar for recent updates of National Aluminium Company Limited Recruitment. Before posting any vacancy details to our website we have a best practice to should verify the NALCO Recruitment from National Aluminium Company Limited official website nalcoindia.com.
How to Get all National Aluminium Company Limited Recruitment detail?
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Daily News Archive
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Lady Eli To Be Sold at Keeneland November Sale
Champion US mare Lady Eli is set to be offered at this year's Keeneland November Breeding Stock Sale, reports Blood Horse. The 5YO, who posted the fifth Gr1 win of her brilliant career when landing the Diana Stakes at Saratoga three weeks ago, will be consigned as part of the Hill 'n' Dale Sales Agency draft. "It is an honor and a privilege to consign a mare of the caliber of Lady Eli," said Hill 'n' Dale president John Sikura in a media statement. "Not only is she uniquely accomplished, winning grade 1 races at 2, 3, 4, and 5, but her courage exemplifies what we love about thoroughbreds. She is class personified and the best of the best. I hope she can win another Breeders' Cup, as well as the Eclipse award she richly deserves." Lady Eli (Divine Park-Sacre Coeur, by Saint Ballado) boasts the outstanding record of 9 wins (including the Gr1 Diana Stakes, Gr1 Gamely Stakes, Gr1 Flower Bowl Stakes, Gr1 Breeders' Cup Juvenile Fillies Turf & Gr1 Belmont Oaks) and 3 placings (including the Gr1 Breeders' Cup Filly & Mare Turf & Gr1 Jenny Wiley Stakes) from 12 starts for US$2,719,800 in earnings. Her record is all the more remarkable given she suffered a potentially career-ending bout of laminitis in July, 2015.


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School uniform is made to keep you in discipline and equality among each student. You can buy your School uniform as a full set of uniform, or you can buy different items separately. You can buy also a different and comfortable socks that you want right here the highest standard product.
Boys school uniforms include
Students studying in primary do not interfere in buying the uniform, but the secondary students buy the uniform of their choice. The dress code is fixed; you have to buy according to that only.
The boys of primary classes can wear both shorts and trousers of their choice but as they grew up and went to secondary classes trousers become compulsory for them. Some schools change their dress code from trouser to shorts during summer. Many students didn't like this. There is a normal dress code for secondary students a white shirt with dark colored pants.
Tie and Blazers:
Tie provides a professional look to the students. Blazers are used during winter to keep them warm. Wearing both tie and blazers students look like a disciplined gentleman. Many schools take advantage of blazers in promoting their school name. They attach a logo on the blazer to be viewed by the others.
Promoting the school brand does not mean that they do not see students comfort. They allow students not to wear blazers and tie during summer time.
Sports Wear:
Sports are the favorite subject of every student in the school. And many schools have physical education as a subject. Since it is a subject regarding sports education, you have to follow its rule. You need a sports uniform in this class. The uniform includes T-shirt and shorts in summer and Tracksuits, jackets, and long track pants in winter season.
Shoes and socks:
According to the uniform of the school, you have to confirm with the school, which type and color of shoes to wear. The Mostly school requires brown or black lace up shoes.
Ladies socks are also pre-decided which color to wear. The color of socks may change at different days of the week. Like some schools want their students to wear a white shoe with white socks on Wednesday or Friday.
From where to buy school uniform
Your school uniform is not a casual clothes that are available in every garment store. There are few fixed shops present in the area of your school which sell their school uniform. The shopkeepers have already consulted with the school and bought the uniforms and accessories required. You can buy a full set of uniform from the store, or you have an option to buy individual things. If you need only shirt or trouser or any other item, then you need not buy the full uniform set. This will save your money, and it will be in your budget.
What To Buy In A School Uniform
School uniform is made to keep you in discipline and equality among each student. You can buy your School uniform as a full set of uniform, or you can buy different items separately. You can buy also a different and comfortable socks that you want right here the highest standard product.


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January 5th 2017
How was your break and what did you do?
During my break all I did was stay home and play games all night. My break was okay except when GTA stopped working and i had to buy the game again. I also spent so time at an uncles house playing with my cousins and celebrating Christmas and New Years at there house.
January 6th 2017
What is the most trouble you have ever given your parents? What is the most enjoyment you have ever given them?
The most trouble that i have given my parents was when I broke the motor in my dads truck for forgetting to put oil in it. The enjoyment that i have given my parents is not getting in trouble a lot.
January 10th 2017
Does writing help you express your feelings?
Writing doesn't help me express my feeling because i hate writing and i am bad at it. I also don't talk about my feelings so i just express them vocally.
January 12th 2017
What dream can you conceive? Can you believe it? Can you achieve it?
A dream that i want to achieve is to own my own truck and I think that I can achieve that goal buy nest year because all I need is to work in the summer to buy it. I also dream that I can go to college and graduate in finance. Finally I want to able to support my family in the future.
January 13th 2017
What are you doing this weekend
This weekend im going to stay at home and play games or sleep all day long.Or i might work if my dad wants to take me to work.
January 17th 2017
How do you decide if you like someone? How do you show interest in them?
I decide if i like some one if they are nice to me and care.I show interest by saying hi.
January 19th 2017
Have you ever "passed on a kindness"?
Yes i have passed on kindness when a friend bought me tacos in the morning sop the next morning i went and bought tacos and gave them to another friend.I also try and to help others when i am doing something good in class and they need help.
January 24th 2017
Who is your biggest fan?
My biggest fan is my mother because she supports ,me in everything and stands by my side when i need it. She helps me out in life and how to be a good person and why. My mother is also my biggest fan because when i do something good she cheers for me and when i fail she is also there for me.
January 26th 2017
What do you love most about yourself? What do others love about you?
What i love the most about myself is that i can get along with most people that i meet. I think that what others like about me is that im funny or something else and that i always give people rides home.
January 31 2017
Which of your senses is the most important to you? What would you do without it?
The sense that is more important to me would be my sight because with out it i could not enjoy the beauty in this world. With out it i could not see. I also think that i could live without the others but not sight because its to important
February 2nd 2017
How do you see yourself? How do you think others see you?
I see my self as a funny person that likes to yang out with people. I think or hope they see me as i see myself and not something else. I think they see me as a a friend and someone funny.
February 3rd 2017
Do you treat people as they are, or as they ought to be?
I do treat people as they are, because some people are nice so I treat them nice as well. I would like to treat everyone the same but some people are mean and dont deserve to be treated the same.
February 7th 2017
How were you taught to tell the truth?
I was taught to tell the truth by being told that if i didn't bad things would happen or i would be in trouble.
February 9th 2017
Have your parents ever practiced "long division" on you and your friends?
No my parents have never practiced long division because i dont take friends home. SO my parents dont know my friends. Also they trust me that i hang out with friends that they approve of
February 16th 2017
What was the stupidest thing you have ever done? Did someone persuade you to do it?
The stupidest thing i have done is steal my dads truck to go to a friends house. I didn't get caught but i almost crashed. I have done other things but i dont remember.
February 17th 2017
Any topic of choice.
I just want to know why we have tp do this. I dont mind doing it but i dont like it i wished we could just do a quick write on Friday every week
February 21st 2017
What do you wish you knew then that you know now?
I wish that i knew that you need to do your work in high school because im doing very bad grade wise. I also wished i new that i new i would not do so good with homework
February 28th 2017
What is the most frightening thing that has happened to you? How did you live through it?
The most frightening thing that has happened to me was when i crashed with my dad. I got over it by thinking that everything was alrigh.
March 2nd 2017
Have you ever received an anonymous gift? Have your ever given one? How did it feel?
Yes i have received an anonymous gift and it felt good. I how ever have not given noone an anonymous gift.
March 3rd 2017
What do you try to do "perfectly"? What happens?
I try to play soccer perfectly but i just got frustrated and stooped playing soccer completely. What happens is that you focus to much on it that if you do something wrong you stay mad at that error for a long time.
March 7th 2017
What is the best thing you have seen teenagers do lately?
I think that what teenagers are best at is hare information about them self and others. This is due to thew fact that we use social media almost all days.
March 9th 2017
Has a smile ever changed your day?
Yes a smile has changed my day.
March 21st 2017
What did you do over spring break
I slept all of spring break and played gta on my xbox all nigh long every day.
April 11th 2017
What is the secret of your success? What is the one thing you do that makes you successful?
The secret to my success is to do everything relaxed and not stress over anything. I think that something that makes me successful is being able to stay calm during difficult times.
April 13th 2017
For whom can you make life less difficult today?
I made my band director life less difficult today because i was listening to everything he said and i did what ever he wanted. He was also mad at the band because we were not counting the music right and had to replay the same spot for 20 min.
April 20th 2017
How are you unlike any other person? What makes you unique and different from everyone else?
I have different DNA and thats how im different form everyone else.
April 24th 2017
Are you carrying around "barnacles" in the form of mistakes, regrets, and pain from the past? How could you let go of these burdens.
I do carry them because theres something that i have done that i regret. I let go of them by forgetting about them
april 27th 2017
Have you ever been "burned" by a bad experience? Has a bad experience ever transformed you and turned you into a new person?
I have been burned from a bad experience because i didn't make a select team on 5th grade and i felt that i sucked at soccer. I has because i started to practice a lot.
May 4th 2017
Is there anything you hate doing, but you do it anyway because it makes you a better person? What is it?
I do have something but i still do it for example school because its the law and my parents want me to go to college.
May 12th 2017
What situation in your life requires win-win thinking?
I have to win when i argue even if i am wrong i still have to be right....
Created with images by galiciadeportiva - "real madrid champion copa del rey"


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Gujarat HC Bar waits in anticipation as Yatin Oza decides to attend Justice MR Shah's farewellAugust 9 2018
Gujarat High Court Bar is gearing up for a very interesting day tomorrow. Justice MR Shah of Gujarat High Court, who has been transferred to Patna High Court as Chief Justice, will be given a Full Court farewell at 4 pm tomorrow.
This might sound like a routine convention but there is more to it.
The convention across most Bar Associations requires the President of the Bar Association to speak on the occasion.
And the . . .
This content is restricted to subscribers


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by Dwight "Ike" Reighard 5.0 out of 5 stars (2 customer reviews)
(Love Comes Softly Series, Book 1) by Janette Oke 4.8 out of 5 stars (104 customer reviews)
Also, if you are a fan of Kindle Store bargains, don't miss this weekend post:
Also, if you are a fan of Kindle Store bargains, don't miss this weekend post:
Kindle Nation Daily Bargain Book Alert: 15 Great Reads from 79 Cents to $1.99!
- "Free" in the Kindle Store refers, for now, to the price for download to US-based Kindles. Amazon adds charges for Kindles based beyond US borders.
- Originally posted to Planet iPad 6.14.2010.
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text: Our Store We will carry a variety of candies, nuts & popcorn along with coffee, tea and ice cream. Yes, We Have Ice Cream! Your everyday favorites as well as seasonal flavors. 5 Kidz Kandy offers a variety of candies, nuts & popcorn along with coffee, tea and ice cream from our location on High Street in Waynesburg, PA. Our Menu Mother's Day Tea Party Come join us for our Mother's Day Tea Party on Sunday, May 12! In addition to the tea party, we also have Mother's Day Fruit Bouquets and Chocolate Covered Strawberries available! These are the perfect gifts to show just how special your mother is! See our gallery below Candy - Gifts - Gift Baskets Check out the Photo Galleries Get In Touch Get In Touch If you are human, leave this field blank. Name Email Subject Message reCAPTCHA Submit


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About this book
Despite the increasing necessity for information on allocating dwindling resources, resource-allocation behavior is not nearly so well understood as choice behavior (selection from two or more already defined alternatives, events, or lotteries.)
Although there have been scores of books devoted to the optimal model for making resource-allocation decisions there has never been a book discussing the cognitive aspects of this behavior.
This book answers the question of how people make such decisions while explaining how Linear Programming can be applied within the context of resource-allocation. It also takes the reader step-by-step into several types of problems under varying conditions, including harsh and benign environments, maximization and minimization, multi-dimensional, and cyclical problems.
Bibliographic information
- DOI https://doi.org/10.1007/978-1-4615-1131-1
- Copyright Information Kluwer Academic Publishers 2003
- Publisher Name Springer, Boston, MA
- eBook Packages Springer Book Archive
- Print ISBN 978-1-4613-5408-6
- Online ISBN 978-1-4615-1131-1
- Buy this book on publisher's site


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Confusing food labels explained
January 25, 2019, 11:03 a.m. by Robin Shreeves
There are lots of labels designed to make you think you're buying better food. Are they reliable?
What food expiration dates really mean
May 27, 2017, 11:59 a.m. by Robin Shreeves
In case you're still confused about those 'sell by' and 'best by' dates on food, this infographic spells it out.
How to pair craft beer with vegetarian fare
December 9, 2016, 12:22 p.m. by Robin Shreeves
Beer goes great with meatless and vegan foods, and this thorough infographic offers suggestions for tasty pairings.
What are the hardest languages to learn?
September 6, 2016, 2:03 p.m. by Laura Moss
Some languages would require more than a year of study for a native English speaker, while others would take just weeks.
The care and maintenance of a cast iron skillet
June 11, 2016, 12:15 p.m. by Robin Shreeves
As I learned the hard way, it's easy to ruin the seasoning.
Your perception of food is altered by environmental factors
February 20, 2016, 1 p.m. by Robin Shreeves
A fascinating infographic explains how science says the way a room looks, sounds or feels can affect the way your meal tastes.
How to pair Girl Scout cookies with wine
January 29, 2016, 3:08 p.m. by Robin Shreeves
What's the best wine to pair your Thin Mints and Do-si-dos? We've got the answer.
'Tis the season for superior oysters
December 3, 2015, 9:30 a.m. by Robin Shreeves
This handy infographic explains the 'R' rule and several other pearls of wisdom.
5 pumpkin treat recipes for your dog
November 24, 2015, 1:18 p.m. by Laura Moss
We have some simple ways to feed your pet this popular, tasty fruit.
How do I ripen produce? Never wonder again
November 5, 2015, 6:40 a.m. by Robin Shreeves
This handy guide helps you figure out how to handle certain fruits and vegetables.
33 things your brain doesn't know about itself
October 6, 2015, 11:15 a.m. by Russell McLendon
From the speed of thoughts to the sense of free will, here's a crash course on what's going on in your cranium that your brain is unaware of.
What does a Big Mac do to your body?
September 24, 2015, 3:48 p.m. by Mary Jo DiLonardo
Viral infographic explains the process, but nutritionists say it goes too far.
7 things you never knew about dragonflies
How safe is cured, smoked or salted fish?
13 odd facts about Edgar Allan Poe
Parallel worlds exist and interact with our world, say physicists
10 strange and beautiful horse breeds
The truth about the tree that grows 'brains' and scares small children
Your 2019 fall foliage guide
Now you know the best time to be a 'leaf peeper' in any part of the U.S.
Why do leaves change color in autumn?
Learn about the natural mechanisms that produce breathtaking fall foliage each year.
Test your fall knowledge
The days are getting shorter and pumpkin spice seems to be everywhere: It must be fall.
10 best places outside the U.S. for fall color
These places around the world that equal U.S. locales when it comes to colorful scenery.
5 classic fall recipes
Roasted veggies and soups of all kinds are what we're talking about.


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NBA Draft Up Slightly for ESPN
ESPN's coverage of Thursday's NBA Draft averaged just fewer
than three million viewers (2.99), a slight 1% increase over last year,
according to Nielsen.
The 4.5-hour telecast -- which featured a surprise pick at
No. 1, numerous trades and a testy on-air exchange between ESPN's Bill Simmons
and newly-minted Los Angeles Clippers coach Doc Rivers -- ranks as the net's
second biggest audience for the annual event since it began televising it in
Only the 2011 Draft had more viewers with 3.2 million.
It was the final draft headed by commissioner
David Stern, who
will step down next February.


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The large snowman on the right is on my ironing board. I had an ironing board in the kitchen wall but when I redid the kitchen it had to go. I loved it so much I had a small one put in this entry.
I change this little table often. I have a tin jelly cupboard that is in the other entry and a bench that I move around . I have so much furniture that the big stuff has to stay where it is and I have to change something when I get the urge.
This snowman gets to tell you "Bye, thanks for stopping! I hope you have enjoyed your tour. Have a Merry Christmas!"


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[On Sundays this blog explores life and work in "Sabbath."]
One City – Three Americas
About a week ago I took my first trip to Las Vegas. Friends said it would be like nothing I had seen before, and they were right.
The strip, especially at night, is Disneyland for adults. People flow from casino to casino. Some are going to shows, and some are going to restaurants. The heart of the city, however, beats with the slot machines and gaming tables. This aspect of Las Vegas reflects post-Reagan America, a country that welcomes risks and says losers be damned. We know the house wins, but we play the game anyway. The person playing next to you is not your problem. Win or lose – you are alone.
My friends and I visited another aspect of the country when we went to Hoover Dam. We took a tour of the facility, which was interesting in several ways. The Dam is an engineering wonder, which was completed during the Great Depression. It represents the opposite of the strip: control, security, and shared resources. The water that the Dam holds in Lake Mead is not only used by Las Vegas. Its primary function is irrigation for farms in Southern California that are essential to the nation's food supply. Before the Dam was built, the Colorado River would often flood and ruin crops. For me the Dam represents a country that builds for the future, a shared future.
We also took a tour to see the Grand Canyon. This version of America puts everything in perspective: man is small and pitiful in the face of nature. We can build skyscrapers and rockets that go to the moon. We could never do what nature has done in carving this wonder. This is the America that is too often being lost to our need to build and grow. In Kentucky and West Virginia, smaller wonders have been spoiled in the process called mountain top removal. In Alaska and the Gulf of Mexico, we have fouled the oceans with oil spills. Thank god developers have found nothing of value in the Grand Canyon. . . yet.
I came away from Las Vegas with both fear and hope. My fear is that we are becoming a nation of risk takers who care little about our fellow citizens or the future. Gambling, which was once legal only in a few places, is now a national growth industry. Governors and mayors cry poor and look to casinos as alternatives to increased taxes. I see people who are obviously not wealthy buy $10 or $20 of lottery tickets, their hope for the future. This is the America where risk rules and the winners run the game. Still, I also came away from my trip to Las Vegas with some hope. If we can build Hoover Dam during the greatest financial crisis in the country's history, we can wake up again and work together for the common good. We still have the Grand Canyon to inspire us to protect the planet and its wonders. We still have a chance – if we don't gamble it away.
Some photos
The Dream Machines Beckon
A mural of a worker building Hoover Dam
Wages of workers at the Dam.
Hoover Dam. Photo taken from the Pat Tillman Memorial Bridge
A truly Grand Canyon


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Danny Rose is set to return to action for Tottenham, while his manager says there is no feud between the two.
Tottenham full-back Danny Rose is set to start for Mauricio Pochettino's side against Borussia Dortmund on Tuesday.
The English defender was left out of the 2-0 defeat to Arsenal on Saturday, but his manager is happy to bring him back into the fold to replace the German giants.
Rose criticized Spurs' transfer and wage policy in an interview with The Sun in August, but after being left out last weekend, Pochettino was forced to deny any feud between the two.
The England international has had a tough time dislodging Ben Davies from the side since he returned from injury, and has such been linked with a move away from the club with Manchester United being reportedly interested.
But Pochettino says there are no problems between him and Rose, and is happy to include him in the Champions League clash if the player can prove his fitness.
"He's doing well," he said during a news conference. "The training session on Saturday was tough for him. He will now train with the group and we'll decide if he will play.
"I cannot speak about rumors. If you were to ask me if Danny Rose is here and do we have problems, I say no. No issues."
Spurs confirmed their place in the Champions League last 16 with their memorable 3-1 win over Real Madrid and will guarantee finishing top of the group if they beat Dortmund at Signal Iduna Park.
Mauricio Pochettino insists the defeat to Arsenal will not put a stopper in their momentum going forward, and even suggested the criticism of their performance at the Emirates could help the side going forward.
He also pointed out the performance of referee Mike Dean as a key factor that went in Arsenal's favor on Saturday, picking out the decision not to send of Granit Xhaka and the offside nature of Shkodran Mustafi's goal.
"Our project is a medium to long-term one," he said. "Our project is to win. I am happy that people criticize us sometimes because it means people expect more from us. That is important to put the pressure on, more than we do.
"We are so calm. We know very well that, from two years and a half ago, we improve in every single aspect. Every team in the top six struggles against each other.
"When you lose, always you try to analyze and then try to improve what was wrong. It's true that there were many decisions in the game that were decisive. When you watch again, some actions like Xhaka on [Moussa] Sissoko and Dele Alli it should be Arsenal with 10 men. Sometimes you need luck to win.
"A year ago, we were in Monaco and we were out of the Champions League. In the Premier League, we've made the second-best start since 1992. We're very disappointed because [in] the last game, the expectation was different. But we need to move on."
Spurs face Borussia Dortmund on Tuesday before returning to Premier League action on Saturday when they host struggling and managerless West Brom.


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Check out this beautiful renovated 3 bedroom home located in the amazing community of McKenzie Lake completed with Lake Access. Walking in you are greeted by beautiful laminate floors throughout the main floor, with spacious front office/formal dining room. Open concept kitchen with refreshed cabinets, new stainless steel appliances, huge windows for lots of natural light & large living area with stunning fireplace. Upstairs boasts 2 spacious kids rooms, beautiful master bedroom with 3 pcs ensuite and additional loft area. Great backyard with over-sized deck, perfect for entertaining and a growing family…even space for RV parking. Basement has a great layout just waiting for your design. Great Home, Great Lake Community and seconds from all amenities…This could be the ONE!
Fenced, Golf Nearby, Landscaped, Playground Nearby, Schools, Shopping Nearby, Back Lane, Lake Access Property
Disclaimer: Information herein deemed reliable but not guaranteed by CREB®.
Listing information last updated on December 14th, 2019 at 11:15pm MST.