text:
Sometimes you just get stuck in a rut. Everything in your life seems to stagnate, and nothing you do inspires you anymore. You often feel like time is rushing by, and you're not doing anything meaningful or interesting, you're not making a change. You believe you've missed far too many opportunities, and now it seems so difficult to pull yourself out this way of thinking.
When life starts feeling bleak and slow, it's time to take back the reins and shake off the ennui. But how do you wake up from this stupor and start loving your life again? Well, we've got a few ideas that can help.
Evaluate your life
Begin by pinpointing exactly what's missing from your life. If you're feeling listless and sad, it's important to find the actual cause because you can't work on the problem without knowing what it is first. Do you wish you had a better job? Do you wish you were in a relationship? Do you miss having more free time? Figure out what's holding you back, and then you'll have a better idea of which steps you can take to improve it.
Help someone out
Depression and anxiety can sometimes make us hyper-focused on ourselves, and while you should always put your wellbeing first, it's not a bad idea to actually look around and notice other people and their struggles. It's entirely possible that a little of your time and some kindness could change someone else's life, so doing things like volunteering in a soup kitchen, rescuing a stray from a shelter, or even just giving out compliments could make this world a little brighter. You'll be creating an atmosphere of positivity and generosity around you, and something like this can only make you feel better. It's not about anyone's gratitude either—simply giving without expecting anything in return can be a transformative experience.
Change your surroundings
If you can afford it, travel. Go away somewhere, change your surroundings, and spend time away from drama and problems. Being away will give you some breathing room and allow you to gain a new perspective, so book a room, find a cheap car hire, and drive around as you let your thoughts wander and your stress melt away. Even if you can only get away for the weekend, do it. It can recharge your batteries and make it easier to deal with what's to come.
Realize that it's okay to be still
You don't have to be constantly on the go. It's okay to pause and rest, it's okay to not know what to do, and it's even okay to stagnate. You won't pull out of the rut by blaming yourself and letting anxiety eat you up. It's perfectly alright to be a little lost sometimes because you can still find your way back.
Just because you're not living at a neck-break pace and accomplishing everything you've ever wanted to accomplish doesn't mean you're not successful, and it doesn't mean you're not a lovely, kind person who deserves good things.
Learn your limits
Once you learn and embrace your limits, they are no longer nearly as limiting. Instead of wasting your time and effort on things that you simply don't enjoy and aren't good at, invest your energy into things that appeal to you.
Enjoy the journey itself
If you focus only on the goal, you'll have a hard time reaching it. For example, realizing that you'd need to exercise every day for a year to get the body of your dreams sounds almost like an impossible amount of work, so you're likely to fret and worry and give up before you even begin. In reality, if you'd only spent time exercising instead of stressing over making a commitment to something, you'd probably have already reached all your goals.
Appreciate good things
Don't allow yourself to only appreciate what you have once it's taken away. Your friends, your family, and good things in your life are far too valuable for you to ignore them in your constant pursuit to have more. Learning the value of the things you have and cherishing them is the key to being a lot happier and more satisfied.
Dedicate time to your wellbeing
Self-care is an important part of both mental and physical health. Working out, eating well, taking time off when you need it, and taking care of your skin will remind you that your own wellbeing is important, and spending time focusing on your own needs can make you into a more stable, happier person. Once you've taken care of yourself, you can start taking care of others.
Appreciate what you already have, and work to reach goals you're passionate about. Remember, you're the only one who can determine what it means to be successful, so don't let yourself be guided by what other people want and think is right. Simply do things that make you happy and you'll fall back in love with your life.


text:
While Bitcoin is the Worlds most successful cryptocurrency, many newcomers into this space and the mainstream media talk so much about "crypto" but do you know what they actually mean? As mentioned above Bitcoin is the Worlds most successful and powerful cryptocurrency there's no denying that. But when people mention "Crypto" they don't actually mean bitcoin, they actually mean "Altcoins". The problem with the word "crypto" these days is that it promotes every other shitcoin out there and it doesn't really promote bitcoin in any way shape or form. Many newcomers in the space are mislead into "diversification" and into thinking that bitcoin is boring, they don't realize that without the success of bitcoin most of their favorite shitcoins wouldn't exist. Here are the facts Bitcoin was created, a few years later thanks to its success Charlie Lee aka Satoshi Lite created Litecoin, its success led to Dogecoin, Clams, XCoin re-branded as Darkcoin and now re-branded as Dash, and then in 2014-2016 Etherem based on Ethereum, everyother ERC-20 Token we know today and the future ones to come.
The point is that they don't realize that if Bitcoin fails they all go down the drain. Diversification in this markets is futile, every week we have new top 10-20 coins but the only one that has remained at the top all this time is good ol' BTC. It's pointless to try and get the top 10 coins because they all change except for bitcoin. I could buy something like Dash only to realize it's lost more than 50% of its value in the last 8 months therefore losing me money not only in fiat but losing me bitcoin in the process. Yes, bitcoin will gain and lose value over time but it is much more stable, innovative, and strong than anything else in this space.

subset: commoncrawl


text:
27th March 2019 – Market Abuse: Trade Surveillance Workshop
Time: 1:30pm to 4:30pm
Cost: £399 + VAT
Location: ACA UK offices, 130 Jermyn Street, London, SW1Y 4UR
Workshop Overview:
This workshop will demonstrate how an asset manager or trader might seek to make gains or to reduce losses, either personally, for a portfolio, or for another, by breaking the rules set down in MAD.
The workshop will look at each of the areas covered in MAD and put them in to real life situations, including the use of jargon used in front offices and how they are used.
Course Objectives:
The objectives are to provide delegates with:
- An understanding of how an asset manager/trader could seek to benefit given specific situations.
- Ideas on how trade surveillance and electronic communications can be used in each instance to monitor and control illegal activity.
- An opportunity to benchmark the relevant systems and controls in place at their firm.
- A chance to put questions to an experienced senior executive to enhance your knowledge of what a trader could get up to.
Key Topics
These are the key areas the workshop will seek to cover but flexibility, with topics discussed being driven by the participants is key to value gained from attendance:
- Spoofing and Layering
- Front Running Orders
- Inside Information
- Cartels and Social Media
- Running a Cartel
- Cybercrime
- Trading at off-market prices
- Hide position
- Side by Side Investments
- Fixing the Rate
- Starting Rumours
- System Errors
This workshop can also take place at your office and be tailored to your specific requirements.
Course aimed at: The delegates that will be interested to attend will be those working in Compliance or Internal Audit and the back office (Operations).
If you would like to discuss your training requirements in more detail please contact Graham Dix on 020 7484 3987 or your usual ACA consultant.


text:
Village Green 5553 Pepeekeo St 539a, Honolulu
Introducing FLEX UNITS 3 Bedrooms, 2 bath 2 parking. Uniquely designed flex unit offers an opportunity for multi-generational living. Both unit types come with a master suite with a wet bar and offers lock outs from the entry foyer so that only the washer dryer/entry foyer is shared. Each of these suites have two mail boxes and two suite numbers, allowing for multi-generational families to live together, yet enjoy their separate privacy. Do everything without going anywhere, Hale Ka Lae puts residents comfortably at the hub of everything that matters in Hawaii Kai. Perfect proximity to legendary beaches, parks, waterways and mountain trails. Easy access to schools, shopping malls, restaurants and medical facilities. An even easier stroll to Costco next door.
BBQ, Club House, Concierge, Exercise Room, Meeting Room, Patio/Deck, Pool, Recreation Area, Resident Manager, Trash Chute, Wall/Fence
City, Coastline, Diamond Head, Garden, Marina/Canal, Mountain, Ocean, Sunrise, Sunset
12 - A-2 Medium Density Apartme
No Public Information available.
This condominium is located at 7000 Hawaii Kai Dr 2817, , it is currently priced $791,000 . This Condo/Townhouse has 3 Bedrooms and 2.00 Bathrooms, totaling 1089 Square feet. Built in 2016, this Condo/Townhouse is Active. Represented by June Hj Freundschuh of Avalon Realty LLC, our team of Realtors can represent you at no additional cost.
Based on information from the Multiple Listing Service of the HiCentral MLS®, Ltd. active listings last updated on December 9th, 2019 at 12:32am HST. Information is deemed reliable but not guaranteed. Copyright: 2019 by the HiCentral MLS®, Ltd.
Listing information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.
Some of the active listings appearing on this site may be listed by other REALTORS®. If you are interested in those active listings, our company may represent you as the buyer's agent. If the active listing you are interested in is our company's active listing, you may speak to one of our agents regarding your options for representation.


text:
One of the advantages of contracting is that, every now and then, you get to meet and work with exceptionally talented people. James is one of those individuals and combines an enthusiasm for technology with a passion for quality.
Always on top of emerging languages and libraries he'll quickly become a primary asset on any development effort. His in-depth knowledge across a massive range of technologies both old and new will quickly emerge as a reference point for everyone else in your organisation. Eager to share this knowledge, his work as developer advocate, blogger and a presenter at meetups and conferences is highly respected and always well received.
There are only a few people I'd personally try to tempt onto any new team. Without question James is one of them.
James is a talented and affable software developer and architect, with a knack for appreciating the big picture at the same time as taking care of low level technical details.
James has an excellent grasp on good quality software development and design and communicates this easily and by example to other team members as well as management and customers. James makes qualified and justified technical decisions in order to help deliver the best work possible to meet the customer's needs.
James keeps himself at the forefront of developments in technology and techniques and is a passionate speaker and mentor, willing to share his knowledge for the improvement of the team and the organisation. James acts as a mentor for other less experienced team members, demonstrating professionalism and enthusiasm for his job.
James can be trusted to make the right commercial and engineering decisions for the situation at hand. I would be both excited and reassured to have James on my team in the future.


text:
Tuesday, July 9, 2019
The One
The one in the loft over on Greenwich Street who used to sing Brecht songs in the moonlight. The one on Horatio with the red hair and the broken nose. The one in the balcony of the Palladium. The one from Texas in the Pickwick Arms. The one from New Orleans in clown shoes. The one with the tattoo feather running down her forearm. The one with the boyfriend whose motorcycle was broken down in their bedroom. The one with the ballerina neck from Maine. The one whose mother died the year before. The one who tasted like tapioca and copper. The one whose father was drinking himself to death. The one in the bookshop. The one in the liquor store. The one in the bar. The one in the airport. The one with no window shades on Ludow. The one on her way to Block Island. The one from London. The one who died. The one who moved to Oregon. The one who opened a bookstore in Vermont. The one with gin in her raincoat. The one. The another one. Then no one. The one.
Posted by Ivan Robertson at 1:27 PM
Subscribe to: Post Comments (Atom)


text:
Be Proactive:
We can choose to handle vexing problems by being reactive or becoming proactive. We all experience frustrations in our careers, in our relationships, and in our lives in general. What can we do to handle problems with co-workers, with family, and with friends? Steven R. Covey talks about the magic of being proactive. A coworker may have failed to relay a message effectively. A family member might come across as critical and judgmental. A friend may behave in a way that is defensive, offensive, and rude. Proactivity would involve the ability to look beyond the actions, to refuse to judge, and to find ways to address the situation in a way that is respectful toward the other person and toward self. It's a win-win situation.
Is someone offending you at work? It might help to take a step back and get into that person's reality. Figuring out what that person wants and needs and working to address those needs might make the work situation more endurable and ease the path toward a hope filled employee, employer relationship. It would certainly take time and effort, but the rewards could be enormous.
Is a family member creating problems? Active listening can smooth over many trials and tribulations. Simply saying "I hear you saying that——" or "Can you explain your position so I can understand it more clearly" can be great tools for understanding.
Being proactive involves thinking and acting in ways that involve respect, honor, and direct communication. Work to build bridges, not chasms. Work to construct relationships, not break them down. And work to be a team player, and not hunker down in isolation.
Are you a team player? Do you listen and respond with respect? Do you endeavor to be proactive? Ask yourself those questions. Live in respect for self and others. Your life will be more hope filled as a result.
Barbara altman is the author of Hope Shines Eternal, available on amazon and soon to be released Passages to Your Hope.


text:
The Races:
Half Marathon, 5k and Flannery's Kids Fun Run (1k)
Event Info:
April 13th, 2019 Starting at the John Allison Public House at 8AM.
Kids Race Start Time: 8:15am
5k and Half Marathon Start Time: 9:00am
Packet Pickup:
Friday, April 12th – 6:30-8pm in the John Allison Public House Banquet Room
We will also have race day packet pickup!
The Beneficiaries:
Proceeds from the days races will be spilt 50/50 and benefit the Greencastle-Antrim Education Foundation and the Greencastle Blue Devils Track and Field Program.
Find out more about the Greencastle – Antrim Education Foundation at https://gaefonline.org/
Runner's Benefits:
All runners will receive a Tshirt along with a gift bag full of goodies.
Runner's of the 5k and Half will also receive an entry to a drawing for a week long cabin stay at Raystown Lake!
Other Events:
The Greencastle Craft Beer Festival will follow the Pub Run. All runners will automatically qualify for a $10 discount on their Beer Festival Ticket. Present your runner badge at the Pub Run After Party (John Allison Public House Outdoor Seating area) to receive the discount. To find out more about the craft beer festival please visit https://www.facebook.com/greencastlecraftbeer/


text:
Oseltamivir - Article oseltamivir phosphate; Tamiflu
Article: Oseltamivir
|Systematic (IUPAC) name
1-carboxylic acid ethyl ester
|CAS number
|ATC code
|Chemical data
|Mol. weight
|312.4 g/mol
|Pharmacokinetic data
|hepatic, to GS4071
|Half life
|6–10 hours
|renal (GS4071)
|Therapeutic considerations
|Pregnancy cat.
B1 (Australia), C (U.S.)
|Legal status
Schedule 4 (Australia)
Oseltamivir (INN) (IPA: [ɒsɛlˈtæmɪvir]) is an antiviral drug that is used in the treatment and prophylaxis of both Influenzavirus A and Influenzavirus B. Like zanamivir, oseltamivir is a neuraminidase inhibitor. It acts as a transition-state analogue inhibitor of influenza neuraminidase, preventing new viruses from emerging from infected cells.
Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It is a prodrug, which is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071). It was developed by Gilead Sciences and is currently marketed by Hoffmann-La Roche (Roche) under the trade name Tamiflu. It is generally available by prescription only.
With increasing fears about the potential for a new influenza pandemic, oseltamivir has received substantial media attention. Production capacity is limited, and governments (and even some private individuals) are stockpiling the drug.
Clinical use
Indications and dosage
Oseltamivir is indicated for the treatment of infections due to influenza A and B virus in people at least one year of age, and prevention of influenza in people at least 1 year or older. The usual adult dosage for treatment of influenza is 75 mg twice daily for 5 days, beginning within 2 days of the appearance of symptoms and with decreased doses for children and patients with renal impairment. Oseltamivir may be given as a preventive measure either during a community outbreak or following close contact with an infected individual. Standard prophylactic dosage is 75 mg once daily for patients aged 13 and older, which has been shown to be safe and effective for up to six weeks. (Roche, 2005; Rossi, 2006)
Use in avian influenza
It has also been found that the standard recommended dose incompletely suppresses viral replication in at least some patients with H5N1 influenza, rendering therapy ineffective and increasing the risk of viral resistance (de Jong et al. 2005). Accordingly, it has been suggested that higher doses and longer durations of therapy should be used for treatment of patients with the H5N1 virus (de Jong et al. 2005, Ward et al. 2005). See Resistance section, below.
Chokephaibulkit et al recommend the use of oseltamivir in pediatric patients, based on experience with one patient.
Sir Liam Donaldson, UK chief medical officer states in the British Medical Journal that oseltamivir has "lack of convincing evidence" of benefit in treating avian influenza. After following WHO protocols in treating 41 victims of the H5N1 bird flu virus (19% of the world-wide cases of bird flu reported to date), Nguyen Tuong Van, MD, who runs the intensive care unit of the Center for Tropical Diseases in Hanoi, Vietnam concluded that Tamiflu, the drug most widely stockpiled around the world to combat a potential bird flu pandemic, is "useless." According to this article, the WHO confirmed Van's experience stating that Tamiflu has not been "widely successful in human patients", but speculated the drug has not been administered until late in the disease in many Asian countries.
Co-administration with probenecid
It has been suggested that co-administration of oseltamivir with probenecid could extend the limited supply of oseltamivir. Probenecid reduces renal excretion of the active metabolite of oseltamivir. One study showed that 500 mg of probenicid given every six hours doubled both the peak plasma concentration (Cmax) and the half-life of oseltamivir, increasing overall systemic exposure (AUC) by 2.5-fold. (Hill et al., 2002) Although the evidence for this interaction comes from a study by Roche, it was publicised only in October 2005 by a doctor who had reviewed the data (Butler, 2005). Probenecid was used in similar fashion during World War II to extend limited supplies of penicillin, and is still currently used to increase penicillin concentrations in serious infections.
Dosage forms
Oseltamivir is marketed by Roche under the trade name Tamiflu, as capsules (containing oseltamivir phosphate 98.5 mg equivalent to oseltamivir 75 mg) and as a powder for oral suspension (oseltamivir phosphate equivalent to oseltamivir 12 mg/mL).
Adverse effects
Common adverse drug reactions (ADRs) associated with oseltamivir therapy include: nausea, vomiting, diarrhoea, abdominal pain, and headache. Rare ADRs include: hepatitis and elevated liver enzymes, rash, allergic reactions including anaphylaxis, and Stevens-Johnson syndrome. (Rossi, 2006)
Various other ADRs have been reported in postmarketing surveillance including: toxic epidermal necrolysis, cardiac arrhythmia, seizure, confusion, aggravation of diabetes, and haemorrhagic colitis.
Neurological effects
In May 2004, the safety division of Japan's health ministry ordered changes to the literature accompanying oseltamivir to add neurological and psychological disorders as possible adverse effects, including: impaired consciousness, abnormal behavior, and hallucinations. Various cases of psychological disorders were associated with oseltamivir therapy between 2000–2004, including several deaths.
On 2005-11-18 the United States Food and Drug Administration (FDA) issued a report regarding the paediatric safety of oseltamivir, which stated that there was insufficient evidence to claim a causal link between oseltamivir use and the deaths of 12 Japanese children (only two from neurological problems). However, it was recommended that a warning was added to the Product Information regarding rashes associated with oseltamivir therapy (Pediatric Advisory Committee, 2005).
Mode of action
Oseltamivir is a neuraminidase inhibitor. By blocking the activity of the neuraminidase, Oseltamivir prevents new viral particles from being released by infected cells.
As with other antivirals, resistance to the agent was expected with widespread use of oseltamivir, though the emergence of resistant viruses was expected to be less frequent than with amantadine or rimantadine. The resistance rate reported during clinical trials up to July 2004 was 0.33% in adults, 4.0% in children, and 1.26% overall. Mutations conferring resistance are single amino acid residue substitutions in the neuraminidase enzyme (Ward et al., 2005).
Mutant H3N2 influenza A virus isolates resistant to oseltamivir were found in 18% of a group of 50 Japanese children treated with oseltamivir (Kiso et al., 2004). This rate was similar to another study where resistant isolates of H1N1 influenza virus were found in 16.3% of another cohort of Japanese children (Ward et al., 2005). Several explanations were proposed by the authors of the studies for the higher-than-expected resistance rate detected. First, children typically have a longer infection period, giving a longer time for resistance to develop. Second, Kiso et al. (2004) claim to have used more rigorous detection techniques than previous studies. Third, the dosage regimen in Japan is different from that of other nations, and some children may have been given a suboptimal dosage of oseltamivir.
High-level resistance has been detected in one girl suffering from H5N1 avian influenza in Vietnam. She was being treated with oseltamivir at time of detection (Le et al., 2005; World Health Organization, 2005).
de Jong et al. (2005) describe resistance development in two more Vietnamese patients suffering from H5N1, and compare their cases with six others. They suggest that the emergence of a resistant strain may be associated with a patient's clinical deterioration. They also note that the recommended dosage of oseltamivir does not always completely suppress viral replication, a situation that could favor the emergence of resistant strains. Moscona (2005) gives a good overview of the resistance issue, and says that personal stockpiles of Tamiflu could lead to under-dosage and thus the emergence of resistant strains of H5N1.
Resistance is of concern in the scenario of an influenza pandemic (Wong and Yuen 2005), and may be more likely to develop in avian influenza than seasonal influenza due to the potentially longer duration of infection by novel viruses. Kiso et al. (2004) suggest that "a higher prevalence of resistant viruses should be expected" during a pandemic.
The genetic sequence for the neuraminidase enzyme is highly conserved across virus strains. This means that there are relatively few variations, and there is also evidence that variations that do occur tend to be less "fit." Thus, mutations that convey resistance to oseltamivir may also tend to cripple the virus by giving it an otherwise less-functional enzyme. The lack of variation in neuraminidase gives two advantages to oseltamivir and zanamivir, the drugs that target that enzyme. First, these drugs work on a broader spectrum of influenza strains. Second, the development of a robust, resistant virus strain appears to be less likely (Ward et al., 2005). It is worth noting that the oseltamivir-resistant strains detected by Kiso et al. (2004) all appeared within individual children after treatment with oseltamivir – the children did not catch the resistant strains in human-to-human or bird-to-human transmission.
Pandemic fears
Oseltamivir was widely used during the H5N1 avian influenza epidemic in Southeast Asia in 2005. In response to the epidemic, various governments – including those of the United Kingdom, Canada, United States and Australia – stockpiled quantities of oseltamivir in preparation for a possible pandemic. Though large, the quantities stockpiled would not have been sufficient to protect the entire population of these countries.
In October 2005, the Indian drug company Cipla announced their plan to begin manufacture of generic oseltamivir without license from Roche. Most patent laws allow governments to authorise supply from generic companies, subject to remuneration to patent owners to address public health problems, including emergencies, although Roche has announced its intention to remain the sole supplier of the drug. Cipla argues that it can legally sell oseltamivir to India and 49 other developing countries, possibly as early as January 2006. Also in October, it was announced that Roche was in discussions with four generic drug manufacturers about the possibility of issuing sublicenses to increase production.
In late October 2005, Roche announced that it was suspending shipments to pharmacies in the United States and Canada until the North American seasonal flu outbreak began, to address concerns about private stockpiling and to preserve supplies for seasonal influenza. It said that, when distribution resumes in Canada, the remaining available drug will be saved for use in high-risk settings like long-term care facilities and hospitals. [1][2][3] Sales were suspended in Hong Kong as well, and on November 8, also in China. Roche said it would instead send all supplies to China's health ministry[4].
On November 9, 2005, Vietnam became the first country to be granted permission by Roche to produce a generic version of oseltamivir[5]. The week before, Thai authorities said they would begin producing generic oseltamivir, claiming that Roche had not patented Tamiflu in Thailand[6]. The first Thai generic oseltamivir was produced in February 2006 and are to be available to the public in July 2006[7].
In December 2005, Roche also signed a sublicense for complete oseltamivir production with China's Shanghai Pharmaceuticals, and by March 2006 a sublicense had also been granted to India's Hetero [8][9]. In June 2006, the Chinese government gave Shanghai Pharmaceuticals permission to proceed, based upon tests of the domestic production. The company said it planned to market the drug by the end of the month.[10][11]
In late May 2006, the World Health Organization asked Roche to be ready to ship an emergency stockpile of oseltamivir to Indonesia if needed. The alert was in response to suspected human-to-human transmission within a family and was planned to last for two weeks [12][13].
U.S. Government policy and oseltamivir
In November, 2005, U.S. president George W. Bush requested that Congress fund $7.1 billion in emergency spending for flu pandemic prepardness (the Senate had already passed an $8.1 billion bill)[14]. Bush's plan included $1.4 billion for government purchases of antiviral drugs[15].
Some commentators (e.g., [16]) question the motives of the U.S. government's endorsement and planned purchase of oseltamivir, noting Secretary of Defense Donald Rumsfeld's close ties to Gilead Sciences, rightsholder to the oseltamivir patent. Rumsfeld is a former chairman of Gilead, and federal disclosure forms indicate that he owns between USD$5 million and USD$25 million in Gilead stock (Schwartz 2005 [17]). The rise in Gilead's share prices from USD$35 to USD$57 per share will have added between USD$2.5 million to USD$15.5 million to Rumsfeld's net worth.
On the other hand, at least one Democratic Senator has criticized Bush for not planning to buy enough antiviral drugs [18].
Personal stockpiling of oseltamivir
The short supply of oseltamivir has prompted some individuals to stockpile the drug. Several American states, including Massachusetts and Colorado, have issued advisories strongly discouraging this practice.
One argument against individual stockpiling is that limited drugs should be kept for more strategic or ethical deployment, that is, to hard-hit areas, to people in critical roles (e.g., healthcare and government workers), to people vulnerable to seasonal flu, or to people who actually have come down with avian influenza. Ethical arguments are sometimes made: Why should affluent people (or nations) have preferred access to antiviral medications? Illegal importation may divert the drug from poorer countries where the risk of avian influenza is actually higher.
In the New England Journal of Medicine, Moscona (2005) argues that the use of personal stockpiles of oseltamivir could result in the administration of low dosages, allowing for the development of drug-resistant virus strains. Many stockpilers will only have ten 75 mg pills (the current recommended dosage for oseltamivir), but this may be insufficient for the treatment of H5N1. (de Jong et al., 2005)
Another argument is that it would be difficult for home users to determine whether illegally-imported Tamiflu is counterfeit. This is genuinely a potential problem, but, in the face of a shortage, some individuals may be willing to face such a risk. In December 2005, 53 packages of counterfeit Tamiflu tablets were intercepted by the US Customs Service in South San Francisco. The packages were labeled "Generic Tamiflu". Roche officials know of only one instance of counterfeit Tamiflu appearing outside of the United States: incorrectly-labelled tablets found in Holland, which contained only Vitamin C and lactose. However, sophisticated criminals could produce convincing fake packaging in the future. [19][20]
A fourth purported problem is that the H5N1 virus can be reliably diagnosed only in a small number of labs around the world; therefore, there is no way for home users to know whether flu-like symptoms are the result of avian flu or a more benign ailment. This argument lacks face validity, since treatment must begin before such tests results would be available anyway.
Veterinary use
Oseltamivir appears to be active against canine parvovirus, feline panleukopenia, the canine respiratory complex known as "kennel cough," and the emerging disease dubbed "canine flu", an equine virus that began affecting dogs in 2005. Veterinary investigation of its use for canine parvo [21] and canine flu [22]is ongoing, but many shelters and rescue groups have reported great success employing oseltamivir in the early stages of these illnesses.
Chemical synthesis
Commercial syntheses
The current production method includes two reaction steps with potentially hazardous azides. A reported azide-free Roche synthesis of tamiflu is summarised graphically below:
The synthesis commences from naturally available (−)-shikimic acid. The 3,4-pentylidene acetal mesylate is prepared in three steps: esterification with ethanol and thionyl chloride; ketalization with para-toluenesulfonic acid and 3-pentanone; and mesylation with triethylamine and methanesulfonyl chloride. Reductive opening of the ketal under modified Hunter conditions (JOC 1993, 58, 6756) in dichloromethane yields an inseparable mixture of isomeric mesylates. The corresponding epoxide is formed under basic conditions with potassium bicarbonate. Using the inexpensive Lewis acid magnesium bromide diethyl etherate (commonly prepared fresh by the addition of magnesium turnings to 1,2-dibromoethane in benzene:diethyl ether), the epoxide is opened with allyl amine to yield the corresponding 1,2-amino alcohol. The water-immiscible solvents methyl tert-butyl ether and acetonitrile are used to simplify the workup procedure, which involved stirring with 1 M aqueous ammonium sulfate. Reduction on palladium, promoted by ethanolamine, followed by acidic workup yielded the deprotected 1,2-aminoalcohol. The aminoalcohol was converted directly to the corresponding allyl-diamine in an interesting cascade sequence that commences with the unselective imination of benzaldehyde with azeotropic water removal in methyl tert-butyl ether. Mesylation, followed by removal of the solid byproduct triethylamine hydrochloride, results in an intermediate that was poised to undergo aziridination upon transimination with another equivalent of allylamine. With the librated methanesulfonic acid, the aziridine opens cleanly to yield a diamine that immediately undergoes a second transimination. Acidic hydrolysis then removed the imine. Selective acylation with acetic anhydride (under buffered conditions, the 5-amino group is protonated owing to a considerable difference in pKa, 4.2 vs 7.9, preventing acetylation) yields the desired N-acetylated product in crystalline form upon extractive workup. Finally, deallylation as above, yielded the freebase of oseltamivir, which was converted to the desired oseltamivir phosphate by treatment with phosphoric acid. The final product is obtained in high purity (99.7%) and an overall yield of 17-22% from (−)-shikimic acid. It is noted that the synthesis avoids the use of potentially explosive azide reagents and intermediates; however, the synthesis actually used by Roche uses azides. Roche has other routes to oseltamivir that do not involve the use of (−)-shikimic acid as a chiral pool starting material, such as a Diels-Alder route involving furan and ethyl acrylate or an isophthalic acid route, which involves catalytic hydrogenation and enzymatic desymmetrization.
2006 Corey synthesis
In 2006 the group of E.J. Corey published a novel route also bypassing shikimic acid starting from butadiene and acrylic acid. The inventors choose not to patent this procedure which is described below. Strictly speaking the synthesis is a formal total synthesis, as the final product to be characterized was the BOC-derivative (14 in the scheme below).
Butadiene 1 reacts in an asymmetric Diels-Alder reaction with the esterfication product of acrylic acid and 2,2,2-Trifluoroethanol 2 catalysed by the CBS catalyst. The ester 3 is converted into an amide in 4 by reaction with ammonia and the next step to lactam 5 is an iodolactamization with iodine initiated by trimethylsilyltriflate. The amide group is fitted with a BOC protective group by reaction with Boc anhydride in 6 and the iodine substituent is removed in an elimination reaction with DBU to the alkene 7. Bromine is introduced in 8 by an allylic bromination with NBS and the amide group is cleaved with ethanol and caesium carbonate accompanied by elimination of bromide to the diene ethyl ester 9. The newly formed double bond is functionalized with N-bromoacetamide 10 catalyzed with Tin(IV) bromide with complete control of stereochemistry. In the next step the bromine atom in 11 is displaced by the nitrogen atom in the amide group with the strong base KHMDS to the aziridine 12 which in turn is opened by reaction with 3-pentanol 13 to the ether 14. In the final step the BOC group is removed with phosphoric acid and the oseltamivir phosphate 15 is formed.
Production shortage/shikimic acid
In early 2005, Roche announced a production shortage. (See Pandemic Fears, below). According to Roche, the major bottleneck in oseltamivir production is the availability of shikimic acid, which cannot be synthesised economically and is only effectively isolated from Chinese star anise, an ancient cooking spice. Although most autotrophic organisms produce shikimic acid, the isolation yield is low. A shortage of star anise is one of the key reasons why there is a worldwide shortage of Tamiflu (as at 2005). Star anise is grown in four provinces in China and harvested between March and May. It is also produced in Lang Son province, Vietnam. The shikimic acid is extracted from the seeds in a ten-stage manufacturing process. Thirteen grams of star anise make 1.3 grams of shikimic acid, which can be made into 10 oseltamivir 75 mg capsules. Ninety percent of the harvest is already used by Roche in making oseltamivir.
Some academic experts and other drug companies are disputing the difficulty of producing shikimic acid by means other than star anise extraction. An alternative method for production of the acid involves fermentation of genetically-modified bacteria. Other potential sources of shikimic acid include the ginkgo tree. In addition, quinic acid, derived from the bark of the cinchona tree of the Democratic Republic of the Congo, is a potential alternative base material for the production of oseltamivir.
However, as is clear by the multistep synthesis shown above, although the major bottleneck for Roche may be the availability of shikimic acid, production of oseltamivir is very involved. Increasing production volume (by Roche or others) would require construction of extensive new facilities (which may not be amenable to scaleup and, even if identical on paper, may not necessarily produce acceptable yields), and even if current facilities could handle a larger feedstock quantity, there would be a delay in production as the material makes it down the pipeline (~6 months or so).
In March 2006, Roche announced that it was making utilizing the resources of 15 external contractors in 9 countries, allowing production to expand to "as much as 400 million doses annually by the end of this year" [23].
Canadian generic drug company Apotex is attempting to modify Oseletamivir to use a synthetic alternative to shikimic acid.
- Oseltamivir (Drug Digest)
- Tamiflu (Drug Digest)


text:
Santa Barbara embraces its many personalities
Complex geography, climate create distinctive identities
LOMPOC, Santa Barbara County -- Thanks to an extended charm campaign, Paso Robles has come to dominate many perceptions of Central Coast wine, much the way the Napa Valley lords over the regions north of San Francisco.
But if regional character were a numbers contest, measured not in identity but in identities, Santa Barbara County would take that prize in a heartbeat. With its proximity to the ocean and an idiosyncratic (for California) geography defined by transverse valleys, Santa Barbara comes with multiple personalities built in. It has a far more complex tale to tell than its neighbor to the north.
"We applaud what they've done," says Larry Schaffer of Tercero Vineyards in Los Olivos. "They've created a very cohesive message. But Santa Barbara is a big, varied county with so many nooks and crannies, so many distinct climates and microclimates. We're akin to Sonoma in that respect."
Those comparisons to Sonoma County are hardly accidental. Both regions have a complicated relationship with the daily weather incursions of the Pacific, resulting in mesoclimates of staggering diversity. (With its coastline elbowing into the ocean, Santa Barbara is influenced from two directions, the west and the south.)
Like Sonoma, Santa Barbara is that rare place where cool- and warm-climate varieties coexist. It is home to estimable Pinot Noir and Chardonnay in the Sta. Rita Hills, praiseworthy Syrah in Ballard Canyon, highly regarded white and Italian plantings in Los Olivos, and an emergent reputation for Bordeaux-native varieties in Happy Canyon.
For this reason Santa Barbara, like Sonoma, can seem somewhat unwieldy as a region, hard to categorize. Its identity is not so easily defined.
"It's definitely a moving target," admits Rick Longoria, who has made wine here for more than 30 years, "and it can be seen as a bit of a detriment. But on the flip side, you can pick nearly any variety and find a spot where that variety will do very well. That's true for nearly all the reds, including Italian varieties, and many whites, too, from Albarino to Gruner and Riesling. Name another area that has this sort of quality across so many varieties. You'd be hard-pressed."
Embracing its charms
Regional identity might be one thing, but when it comes to cultural identity, Santa Barbara has forged something idiosyncratic and unique in the last decade, spurred into the spotlight brought by the movie "Sideways," which was one long postcard for the county's quirky charms.
If most wine regions spread out their tasting rooms, Santa Barbara has become a tasting destination with several hubs of wine tourism, nearly all of them separated from a winery setting.
Solvang, Lompoc, Los Olivos, Los Alamos - each town has become a nucleus for tasting rooms, catering to its local vintners. There is even a district in the city of Santa Barbara called the Funk Zone, a melting pot of sorts that features producers from all the county's wine areas.
This trend is the direct result of a rather myopic - but ultimately influential - county ordinance. Pressured by residents in agricultural areas, the legislation restricts the number of tasting rooms on agricultural land - where wineries, naturally, are situated. To compensate, wineries relocated their tasting rooms to town centers; their close proximity became a tourist draw, a boon to local economies and a catalyst for other local businesses, and changed communities for the better in the process.
Take Lompoc, an agricultural town on the western end of the Santa Rita Hills. For years, an industrial park on the east side of town served as a low-rent production center for the area's wineries, housing presses and barrel rooms; it became known as the Wine Ghetto.
With its asphalt lots and corrugated buildings, it was homely, practical and serviceable for winemakers - though hardly a destination. But in 2004, Steve Clifton opened a Wine Ghetto tasting room for his Italian-inspired Palmina label.
"I just wanted a place where I could pour wine for clients or salesmen or the press," Clifton says. "Everybody looked at me like I had three eyes."
The growth potential
Within four months, he was scheduling 15 appointments a week. Within six months, he was getting 300 monthly visitors. Soon every other winery in the ghetto had no choice but to throw together a rudimentary tasting room. Crowds followed.
Lompoc, a small town with few amenities, stands to benefit.
"There are rumblings about restaurants and other things," Clifton says. "That's the way things seem to be going."
A town in need of an identity may end up finding one through its wine community. And that may well be the path upon which Santa Barbara County forges a single identity - one weekend at a time, one carload at a time, as wine lovers discover its range of offerings.
Patrick Comiskey is senior correspondent for Wine & Spirits magazine. E-mail: firstname.lastname@example.com


text:
This is one of my favorite pillow styles.
It's cross between a pillow and a cushion…but more pillow than cushion especially if you use a feather insert.
And even though the "box" part of this pillow may be a bit daunting you can do it!
And here's how…
Though the pieces shown in this post are for a larger pillow, the measurements I'm including are for a finished 20″ pillow using a feather insert.
The breakdown of the pieces you need to make this pillow are…
- Top and Bottom – cut 21″x 21″ each.
- Boxing – 2 widths of 54″ fabric cut at 3″ wide. 2 widths of 54″ fabric cut 2.5″
- Ruffles – 6 widths of 54″ fabric cut at 4″ each.
- 18″ zipper
*Due to the extra width involved with the boxing you'll need a pillow insert larger than the finished size of your pillow cover.
For instance, if you'd like your finished pillow to be 20″ you'll need to choose a 24″ pillow insert. If your pillow insert is quite firm then I'd make the finished pillow cover 3″ smaller than the pillow insert.
illustration photo via Threads Magazine
This illustration helps to show the shape of a boxed pillow. Instead of the optional piping or trim we'll be including a ruffle.
1.5″ Ruffles
Sew 3 of the 54″ x 4″ ruffle pieces right sides together, end to end, connecting all three pieces to form a circle. Repeat with the second set of 3 pieces.
Fold the ruffle pieces in half lengthwise to form a 2″ strip.
Gather the ruffles using this gathering technique or this handy dandy little attachment!
Once your ruffle is gathered…
Sew the ruffle to the top of your pillow cover.
Repeat for the bottom of pillow cover.
Your pillow cover will now look like so.
Sew your zipper to the 2 @ 2.5″ pieces of boxing. Once the zipper in sewn in place, trim piece to 3″ keeping the zipper centered.
Sew remaining 54″ x 3″ pieces of boxing together, end to end, right sides together.
Turn under one end of 3″ boxing forming a small hem.
Pin hemmed boxing over the closed end of your zipper (in order to hide zipper pull when pillow cover is finished). Stitch together along outer seam allowance and at the end of the zipper.
This is what your boxing with zipper will look like from the back side.
Place zippered boxing along lower edge of front pillow top, over ruffle, centering zipper along the width of your pillow top.
Sewing with the boxing piece on top (layers are – top to bottom: boxing, ruffle, pillow top) sew pieces together using a 1/2″ seam allowance, clipping fabric as you sew around corners.
Now you have sewn all the way around your pillow top and are getting close to the zipper again.
This illustration shows how the pillow is coming together at this point.
What we're going to do next is bring the boxing around to cover the end of the zipper. Trim any excess boxing fabric being sure to leave enough fabric to turn under for a hem and to cover the end of the zipper.
Here the boxing has been hemmed.
Pin zippered piece over hemmed piece.
*At this point, after the pieces are pinned in place, your layers will be: top to bottom -zippered boxing, hemmed boxing, ruffle, pillow top.
Stitch together.
This shows how the boxing appears after sewn in place to the pillow top.
The hemmed boxing piece is covering the end of the zipper.
Stitch or baste boxing pieces together along seam allowance.
Next is sewing the pillow bottom to the "boxed" pillow top.
The most important step in this process, as you pin the pillow bottom to the boxing, is to make sure you line up the corners of each top with each bottom piece.
In order for the pillow to stay "square" you need to make sure the corners line up.
How to I know this?
Let's just say lopsided cushions are not pretty. Not to mention being a whole lot of trouble to take apart and remake.
The boxed pillow is a bit more time consuming with a few more details than your average pillow cover. So if you're a beginner, I'd suggest trying a few simple pillows first before tackling this one but don't rule it out! It's really a sweet pillow and worth the effort.
The blue floral was my first attempt at making this style of boxed pillow. I made one for each of my older girls when they shared a room. Somehow Kaleigh ended up with both of them and this is still a point of contention. Courtney is still expecting her's to be shipped to California. 🙂
Kaleigh even took one as a prop for their engagement pictures!
Even if Kaleigh did tell everyone the pillow came from TJ Maxx!
Can you believe that?
Well, here's to setting the record straight.


text:
Bell Road is one of the most congested Valley roads, but with the help of a new streetlight system, the regular flow of traffic may be greatly improved. This could be a major improvement for the locals who routinely drive the 34 mile road which spans between Scottsdale and Surprise.
Traffic Lights Will Feature New Smart Technology
Officials are making use of Adaptive Signal Control Technology in order to allow the timing of traffic lights to be adjusted periodically, depending upon the flow of traffic. Transportation departments throughout Arizona have been experimenting with various traffic flow systems, and Adaptive Signal Control Technology appears to be the most powerful tool. Essentially, what the system does is gauge the traffic demands on busy streets, calculate the quickest algorithms that will allow for the greatest flow of traffic, and then implement those algorithms directly into the timing of each traffic light.
Busy Intersections Will See The System First
Intersections that are most frequently clogged with traffic will be equipped with the system initially. If implementation of the system is successful, it is highly likely that it will be expanded elsewhere in Scottsdale and beyond.
Many commuters who are used to the stop and go, bumper to bumper traffic on Bell Road are waiting in eager anticipation to experience the improved traffic flow system.
The project itself has been made possible due primarily to federal funding which has amounted to 2.7 million. If the system is successful, then officials have the option of using Bell Road as a major transportation detour route when the freeway is closed. Ultimately, the project is expected to be completed by spring. Officials hope that traffic conditions are greatly improved, and that accidents occurring during bumper to bumper commute hour traffic are less frequent.


text: Ultimate Deo Stick with Baldessarinis fragrance from 2015 developed by perfumer Geza Schön. It has base notes of frankincense, amber, leather and patchouli. At the top you can smell Peruvian pink pepper, bergamot and mandarin. In between there are floral notes of magnolia, jasmine and the African freesia plant.Volume75 ml


text:
One of the largest no-kill shelters in Georgia, Athens Area Humane Society sees upwards of 5,000 animals come through its door annually. Their number one initiative is providing neuter and spay services for all animals they serve with their full-time surgical team. This shelter is highly engaged with the community, hosting events year-round like the Santa Bar Crawl, Paint Your Pet, the Brew Classic, and many more! And if you are in desperate need of cheering up, Athens Area Humane Society maintains a live feed of all of their adoptable kittens on their website.
Ten years ago, a group of Georgia locals founded Circle of Friends Animal Society to support the animals that were being neglected by the rescue system because of chronic health conditions or breed. They started out small with a staff of the eight founding members and grew to be a little army. Today, COFAS facilitates rescue and rehabilitation using a vibrant network of foster homes and partnerships with local stores to host adoption events weekly. COFAS also partners with Wooftrax, so participating members can donate to them for every mile they walk with their pup.
This non-profit rescue operates solely from their foster families, usually taking animals that have been surrendered or abandoned by former families. It is for this reason that a majority of their adoptable animals are taken quickly, as they are already well trained and socialized. Despite the lack of formal shelter space, Athens Canine Rescue rehomes hundreds because of the fierce dedication to the dogs of Athens. When they are not developing foster family connections, this shelter hosts several fundraisers like 5Ks and meet & greets.


text:
Kiosk printers are advanced printers which can provide optimal solutions to any printing problems. These kiosk printers can print in any formats and type. From tickets, passport size to printing receipts, everything can be done using kiosks.
The size can be adjusted too. From A4 size printing paper to shrinking in 60 mm width, all size types can be printed. The installation also is not that problematic, so application on different types of fields is applicable. Everyone who is looking for high quality, fast and reliable printing will go for kiosk printers.
The manufacturing of self-service kiosk is also on the run, as they are more reliable and easier to maintain.
3d printing technology has advanced to a high level as of now. The future has excellent opportunities and almost a world of learning lies ahead in front of us. Here we are going to discuss the future of 3d printing kiosk.
When it comes to 3d printing, one may be sure that the future will be highly eventful. The trials and experiments are still going on in full scale, and most of the commercial companies are testing to see what more processes can be applied to make the 3d printing an entire household that will be used for almost all purposes.
The design for the manufacturing process and the real-life application has still a massive gap between them though. To minimize this gap, companies have come up with educational initiatives that are available to every manufacturer and people interested in trying and creating much more helpful practical uses.
Many commercial companies that know how to print and use 3d printing kiosk printers have found applications that are suitable for it and created different parts. However, all of these applications are still in a rudimentary stage.
Various tests are run by companies to see that these machines can operate successfully in the real world without hampering or degrading their performance in any kind. Once these test and experiments reach their completed stage and the doubts or questions about their performances are reduced, the market will be filled with the demand for 3d kiosk printers. By then, every small paper works and related pieces of stuff in an office or even in a house will be done by these printers.
The demand will automatically rise, so the production will also grow in a parallel manner. Also, the need for education which is related to these will increase as well. This will lead to a rising in employment in this sector too. This likely would not happen until the middle part of the 21st century though.
Globally, we see interest in 3d printing kiosks in the automobile industry and medical sector. Automobile parts are also being produced using this technology. It may not be long before an entire automobile can be recreated using 3d printing. In medical, prosthetic limbs and artificial body parts can be created.
This may cause a revolutionary change in the texture of reality, and the young generation may live to see it.
Read more about Additive Manufacturing


text:
Music Villa Recent Vibes
A Look at the Cordoba Mini R & Mini M
CATEGORY: Product News
If you are looking for what could be the ultimate in travel guitars, you need to take a look at the Cordoba Mini M and Cordoba Mini R nylon string travel acoustic guitars. Read On
Electric Guitar Gift Packages for 2017
CATEGORY: Product News
Our electric guitar specialist, Joe Knapp, has put together some great electric guitar packages that include a electric guitar, gig bag, tuner, strap, cable, picks, and a tuner! What a great gift idea!! Read On
2018 Gibson Acoustic Rundown - What's New for 2018
CATEGORY: Product News
With the new year right around the corner, we were excited to get a chance to sit down with Don of Gibson Acoustics to talk about some of the great updates coming to the 2018 Gibson Acoustic Guitar collection. Read On
Best Starter/Kids Guitars (JR1, JR2, APXT2) from Yamaha!
CATEGORY: Product News
We recommend LOTS of starter, junior, and kids guitars to our students. Many guitars in this category can be very cheap, hard to play, and often times hard to keep in tune. For that reason, we picked 3 of our favorite guitars in this category... all of which we'd recommend to any player! They're all quality built, durable, affordable, and stay in tune!! Read On
Did You know? 5 Facts About the Gibson Dove Acoustic Guitar
CATEGORY: Product News
Throughout the years, Gibson has released a number of recognizable acoustic guitars that have found a special place in guitar history. Among those guitars is the Dove Acoustic guitar. Released in 1962, the Dove is still in the Gibson Acoustic Guitar lineup. Read On


text:
Read - Lead - Succeed
(435) 654-0112
Popular Links
The School Community Council (SCC) works to use School Land Trust funds to improve learning for all students. In addition, our council discusses current issues facing our school and acts as an advisory committee for our counselor. The council is composed of parents, teachers, and administrators.
Member Name Phone Role Amanda Porter firstname.lastname@example.com 801-361-6691 Chair (Licensed Parent) Jessica Wagstaff firstname.lastname@example.com 435-671-1424 Vice Chair (Licensed Parent) Piper Riddle email@example.com 435-654-0112 Principal Tessa Wray firstname.lastname@example.com School Employee Peggy Bauer email@example.com School Employee Max Ventura firstname.lastname@example.com Parent Celeni Richins email@example.com Parent Rafaela Mena email@example.com Parent Laura Aguirre email@example.com Parent
2018-19 Meeting Schedule
All meetings are held the 4th Monday of every month at 3:30 pm in the media center (library) at Heber Valley Elementary. The public is invited.
Sept. 24Oct. 22Nov. 26Jan. 28Feb. 25Mar. 25Apr. 22May 27


text:
The wall mounting feature would enable you with the freedom to mount your desktop monitor wherever you like to mount in your home or office. The mounting bracket would enable for easy installation. You should upgrade your workstation and install your monitor at appropriate height for comfort and improving your posture.
It would be pertinent that you should let the computer monitor adapt to your specific height and working style with the desktop monitor mount Singapore. You should be able to mount the monitor with ease with the best in business available at your behest. They would provide you with the right option suitable to your budget.


text:
Monday, October 22, 2012
Spicy Sesame Noodles
This is one of my favorite recipes OF ALL TIME and I've been making it for years. I thought I put it on the blog when I first started it, but I recently realized that I never did. My apologies, because it is so amazing. Well now I'm sharing it. So hopefully you'll forgive me tardiness on this one.
I've included the veggies I like to use, but pick and choose whatever are your favorites. Add a protein in, if you wish (chicken, tofu, etc). Since the whole grain pasta and sesame butter have a lot of protein, I don't bother. If you don't want them to be spicy, you can omit the heat factor and still have a fantastic dish.
Spicy Sesame Sauce
1/2 cup sesame butter (this is not the same as tahini, it's made from roasted sesame seeds)*
2 tbls low sodium soy sauce/tamari/coconut aminos
2 tbls rice vinegar
Juice of 1 lime
1/4 cup natural/sugar-free ketchup (or 1/4 cup tomato paste + 1 tbls coconut sugar)
3-4 tbls finely chopped or minced fresh ginger
3-4 cloves garlic
1/4 tsp Chinese 5-spice powder (optional)
Siracha sauce, birds eye chilis, minced or crushed red chili flakes, to taste (optional)
Salt, to taste
1/2 tsp sesame, peanut or canola oil
1/4 cup water
1/2 lb snow peas, trimmed
2 sweet bell peppers (red, yellow, orange, etc.)
2 lbs mushrooms, halved
1 bunch green onions, sliced
1 lb whole grain spaghetti, broken in half
Whisk together ingredients for sauce in a small bowl. Meanwhile, cook spaghetti to al dente, reserving 1 cup cooking liquid, before you drain it. Saute veggies (excluding green onions) in a large wok or skillet with oil and water, if needed, until tender. Add cooked spaghetti and sauce and toss everything together, adding reserved pasta cooking liquid until desired consistency is acheived. Stir in green onions. Serves 4 as a main.
*If you can't find sesame butter, you can sub tahini + 1 tsp toasted sesame oil.
Posted by Healthy Life Lessons at 5:00 AM
Labels: Asian Noodle Dishes, Dinner, Vegan
Subscribe to: Post Comments (Atom)


text:
This week Facebook reminded me that three years ago I finally finished reading J.R.R. Tolkien's The Fellowship of the Ring. I've always loved the stories and movies but what gripped me the most of that particular book was this quote:
I am not made for perilous quests. I wish I had never seen the Ring! Why did it come to me? Why was I chosen?
'Such questions cannot be answered,' said Gandalf. 'You may be sure that it was not for any merit that others do not posses: not for power or wisdom, at any rate. But you have been chosen, and you must therefore use such strength, and heart and wits as you have.'
As Gandalf encouraged Frodo about the task before him, so too God encourages us in a time such as this. Things come before us that may seem daunting, and to people around us it may indeed appear as if we are unfit for the challenge. However…because of Jesus, because of what he has done for us on the cross and because God calls us his children…with His guidance, the power of the Holy Spirit, and the gifts He's given us, we can pursue what He lays before us despite our feelings of inadequacy! Thank you Lord for this reminder, of how even in our weakness you give us strength!


text:
Thalorien Dawnseeker was a high elf who gained fame for wielding the blade Quel'Delar. He was also a good friend of Lana'thel, who took up Quel'Delar before his death and carried it to Northrend in the service of Prince Kael'thas. During the war against the Scourge, he was part of the defense unit that guarded the Sunwell against the Scourge invasion of Quel'Thalas until he fell in battle against the death knight Morlen Coldgrip. His corpse remains where he fell, on the southern tip of the Dead Scar on the Isle of Quel'Danas.[1]
References Edit
External links Edit
| Preceded by:
Unknown Highborne (earliest known)
| Position:
Wielder of Quel'delar
| Succeeded by:
Community content is available under CC-BY-SA unless otherwise noted.


text:
"A Single Market for the 21st Century": Challenges and Perspectives May 7, 2009Posted by liverpoolchamber in Business.
The Liverpool Law School is organising a conference exploring the Commission's 2007 Single Market Review.
The conference will be held on Thursday 25th June 2009 at the Arena and Convention Centre Liverpool (Monarchs Quay, Liverpool Waterfront).
The conference seeks to deliberate critically upon some of the major issues identified in the Commission Review: for example, how cross border trade can be reconciled with environmental concerns about issues such as "food miles"; how the role of collective labour organisations can be adapted to the demands of the Single Market; how to secure more effective protection for consumers faced with the growing complexity of international trading relationships; the need for reform of banking regulation in the light of the current credit crisis, and indeed the capacity of Single Market to resist protectionist pressures in the face of the global economic downturn; and how to promote the European version of market integration as a "global brand".
Speakers, discussants and chairs include: Jörgen Holmquist (European Commission); Catherine Barnard (University of Cambridge); Niamh Nic Shuibhne (University of Edinburgh); Geert van Calster (University of Leuven); Joanne Scott (University College London); Ioannis Lianos (University College London); Dermot Cahill (University of Bangor); Thomas Ackermann (University of Erlangen-Nürnberg); Anu Arora (University of Liverpool); Marise Cremona (European University Institute); Luigi Daniele (University of Rome "Tor Vergata"); Sacha Prechal (University of Utrecht); Jukka Snell (University of Swansea); Eleanor Spaventa (Durham University).
The conference is generously sponsored by the European Commission Representation in the United Kingdom.
The provisional programme, conference booking form and further information are all available at the online here.
Please note that places are limited and registration will be on a first-come-first-serve basis (further booking requests will be held on stand-by in the event of cancellations). For further information about the conference, please contact Professor Michael Dougan (email@example.com) or Dr Arianna Andreangeli (email@example.com).
No comments yet — be the first.


text:
AN ACT to provide for the establishment of the Zimbabwe Special Economic Zones Authority and to provide for the functions thereof; to provide for the constitution and functions of the Special Economic Zones Board; to provide for the establishment of special economic zones, and the administration, control, regulatory measures and incentives in connection therewith; and to provide for matters incidental to or connected with the foregoing. ENACTED by the Parliament and the President of Zimbabwe.
Note by Veritas: This Act was Gazetted and came into force on 1st November 2016.


text:
You do not truly need to discover almost everything about purchasing or selling properties if you employ a true estate expert does. When a purchaser who has not entered into a Buyer Agency agreement with the broker buys a house, that broker functions as the sub-agent of the seller's broker. The actual estate directory lets you view and evaluate real estate agents, study testimonials, see an agent's current listings and previous sales, and get in touch with agents directly from their profile pages on Zillow.
In Canada, most provinces' laws need the real estate agent to forward all written offers to the seller for consideration or assessment. Its good to have a much better understanding of the genuine estate jargon, like what money held in escrow implies. The property is offered for sale by any genuine estate expert who can promote, show, or negotiate the sale.
A real estate agent will also be capable to save you a lot of time in the approach, because he or she will take the data you give about what you want in a home and find just the proper houses that match the bill. The terms real estate agent and true estate broker are frequently employed interchangeably. You are definitely not alone in employing an agent, and the chances are really great that the party you are purchasing from or promoting to is also employing a real estate agent.
The courses are made to prepare the new licensee mainly for the legal aspects of the practice of real estate and to pass the state licensing exam. Choosing a great home agent is most important for home management who helps you all through the getting process and beyond to completion. If state law allows for the same agent to represent both the buyer and the seller in a single transaction, the brokerage/agent is normally deemed to be a Dual Agent.
A great agent will have a thorough knowledge of the neighborhood markets and will help you in receiving the best worth for your deals. When I was active, although I occasionally listed, I was an exceptional buyer's agent and truly fought for my clients. An estate agent , which is a term utilised in the United Kingdom , is a particular person or company entity whose enterprise is to industry actual estate on behalf of customers.


text:
"The Krystowski Minnow is one of my early original fly designs. I began tying this fly long before I was part of the fly fishing industry and a contract fly designer. It was at a point in my life when I had very limited time to spend behind a vise and, more influentially, when I had very little money to spend on tying material. I needed an all-purpose baitfish streamer that I could use for every occasion. I could not afford to have multiple fly boxes for every species of fish, but I was fishing everywhere and often. I needed a fly for river smallmouth, farm pond largemouth, Spring steelhead, Fall browns, wiper, walleye and northern pike. If I had a handful of Krystowski Minnows in my box I was all set. The fly needed to be cheap to tie, fast to tie and never fall apart...even after being chewed on by northern pike. I have old fishing buddies back in my home town who fish this fly over everything else. The fly is named after a family in northern Ohio who owned a small bass pond and would let me fish and invite me in for dinner. The earliest prototypes of this fly were fished in their pond" -- Jay Zimmerman (Colorado Fly Fishing Reports )
- Category
- Steelheads


text:
We have entered the last quarter of the year. Many IT executives have begun budget plans for the next year, while other organizations have started the new fiscal year already. Either way, Reliant Technology has you covered with these exclusive hardware specials. Whether you are planning IT purchases for the next year, or you are one of the lucky IT departments with surplus budget looking to stock up on some essential data center hardware, save on all your IT equipment needs.
We're bringing you some of the most sought after storage, server, and networking equipment from manufacturers like EMC, Brocade, NetApp, Cisco, HP, and more.
Why Buy Certified Pre-Owned Hardware?
Reliant Technology offers used data storage hardware with warranty. Perks that come with purchasing certified pre-owned equipment include:
Save 30-90% compared to purchasing brand new equipment from the Original Equipment Manufacturer (OEM).
Extend the life of your existing hardware with pre-owned IT upgrades
Add capacity or increase performance without breaking the budget
Skip an unnecessary and potentially expensive hardware refresh
Why Certified Pre-Owned from Reliant Technology?
As the World's #1 Reseller of Certified Pre-Owned Storage & Support, we provide what other resellers and VARs don't. Some of our hardware promises include:
All hardware is thoroughly tested and comes with a 1-year warranty
Dedicated team of experienced engineers and storage specialists can guarantee compatibility
Parts, Upgrades, & Support available for multi-vendor systems
What's Available?
We have a range of storage, server, and networking hardware designed to fit all your data storage needs. Looking to integrate a unified storage system into your NetApp environment? Then a fully configured NetApp FAS6280 might be for you. Want to add capacity and performance to your existing EMC array? Then a V31-DAE-R-15 DAE could be a good fit.
For IT managers looking to enhance their networks, we have specials on Cisco and Brocade switches. Need a few more servers in your environment? Save up to 90% on Dell and HP servers.
For a complete list of our specials check out our hardware specials page.
Ready to Save?
Our equipment list ranges based on availability. If you don't see what you need on our current specials list, our inventory changes daily so don't hesitate to reach out to one of our dedicated storage specialists at 1.877.227.0828, or request a quote.


text:
The art masking fluid works when you apply it direct to the paper and the areas that have been masked are resistant to watercolours. Once dry the section that has the masking fluid on is protected, the latex base fluid can be applied with a brush or a fine nib pen which is ideal when peeling off the section you have covered.
No need to dilute before use, not suitable for soft or damp paper, remove as soon as the painted area is dry and you can removed with an eraser.
For more information on Masking fluid please click here.
A bit about the brand: Founded in 1832, Winsor & Newton are one of the World's leafing brands of fine art materials and has developed a fantastic reputation for reliability, quality and product innovation.
See all the Winsor & Newton range ›
We offer a 100% Money Back Guarantee* on our returns. This however is only available for UK mainland customers.
This may also exclude additional delivery charges that were made to send to you initially.
Saver Delivery - £2.95 on UK orders below £30
In need of your delivery fast?
We offer a 1-2 day service! Once the items have been dispatched through our service provider your item will take 1-2 working days to arrive.
Please see terms and conditions ›


text:
Cooper Interiors
Cooper Interiors recently had the honour of sitting down with world-renowned lighting and furniture designer David Trubridge.
How would you describe your brand?
I don't really like that sort of simplification. I generally see the word brand as a facade built from a marketing spin which is put onto show your public face as a construct. We created a brand from the inside out, that's just our integrity around what I believe in in terms of environmental impact. Making something that is wild and using good products but it's not a sort of construct that's put on to sell the product. They're general expressions of who I am and what we as a company stand for.
How did your time in Antarctica effect the way you work today?
Antarctica really brought out the environmental consciousness in the way we work, although it has always been a large part of who I am. When we renovated our house in Northern England we used second hand slates, made windows out of old ships decking and so on. So, right from the start that's been part of my ethos. But, Antarctica definitely gave it a boost and put things in focus for me. Talking to scientists there in the early 2000's, they knew all about this (global warming) for years but it hadn't really gotten out into the world yet. It was the trip of a lifetime.
What inspired you to start your business?
What is start and when? I started making furniture when I left university and for many years I was designing and making on my own and then I started the company 20 odd years ago. There was no real starting point, one thing grew from another. The original calling to make furniture was a lifestyle choice, living in North England and wanting to get out of the city. The crafting came after that as a sort of a way of making a living in that place.
When did you move to New Zealand?
After establishing my business over 10 years making and crafting my own furniture, we wanted to see the world. We sold the house, the business, the workshop and bought a yacht. We headed off on an adventure and ended up in New Zealand five years later.
What differences have you found in New Zealand's design culture verses England's?
It's hard to say because I left England in 1981, what I remember is not what England is now. They are quite similar really. Here obviously we have a strong infusion of Polynesia which is the biggest difference. I think back to some of the London design festivals and design week and there is a lot of "clever design", design that's coming out of the left brain, it's a novelty it's a gimmick, it's wit, it's irony it's trying to draw attention to itself rather than just being good design. It's trying to perform tricks, which is understandable as it's so hard to make a living out of it. I've seen a little bit of it here but more so in England so that's a big difference.
What do you like most about New Zealand's design culture and history?
Polynesia has been really important to me since we came here, the whole story of the Polynesian migration fascinates me. This culture was crossing oceans before Britain was crossing rivers in a coracle which is amazing. I think it's one of the most unsung feats of human culture, to be able to navigate across the Pacific Ocean without any instruments, purely through their connection to the world around them and understanding it. They are moving, the skies are moving, the seasons are changing, the stars are in different places at different times of the year they knew where they needed to be underneath those stars between those islands. It's that kind of connection to the environment around them and understanding of it that I find the most interesting about this part of the world.
In today's world, what we are realising is that there is a massive resurgence of first nations, indigenous culture asserting themselves, saying we actually are just as important as you, history didn't begin with the West. You might have written the book but we have our own history which is different and in some places longer back than that. Our culture (British) is a rapacious one. It's an inquisitive one, it destroys the environment for its own end it won't last. Those cultures will because they understand the balance, that's why I like living down here.
What is your favourite experience within your design career?
What I enjoy doing most is more installation and storytelling kind of work. The way we do it is to create an installation around a story, which goes onto creating products we still sell today, but the whole thing was a story. The story gave it a reason to be.
What is the best piece of advice you've ever been given?
Launch out into the deep.
Originally published on the Cooper Interiors Blog


text:
International branded products from HEINEMANN Duty Free
1-M- for every euro
Exclusive cosmetics, perfume, spirits and more
Monthly special offers at 30% discount
At HEINEMANN Duty Free Shops at the airport, passengers will find international branded products at great prices: Perfumes and cosmetics, fine wines, a wide range of first-class spirits, lots of regional products, new special offers every month with an additional 30% discount and much more. When you shop you receive 1 award mile per 1 euro you spend. HEINEMANN will also assist you with extensive benefits and excellent service - before, during and after your trip.
This is how easy it is to earn award miles with HEINEMANN
- Please show your Miles & More service card at the check-out.
- You will receive 1-M- per 1 euro you spend.1
- The award miles will be credited to your account automatically within six weeks.
- You can earn miles at HEINEMANN Duty Free, Travel Value & Tax Free Shops at airports in Germany, Austria, Italy and Denmark.
Online shop and delivery service
Passengers can shop with ease at heinemann-shop.com and have everything delivered conveniently to their door - at the usual low prices and with free delivery on orders of 75 euros or more. To get the exclusive benefits, you need a valid EU flight ticket and a delivery address in Germany. You can also place your order as early as three months before your flight. Yoemau also have the option of using the delivery service in the shop at the airport and having your purchases delivered right to your door.2
Browse the HEINEMANN online shop at www.heinemann-shop.com now.
Duty-paid and taxed tobacco products (with a customs/revenue seal), newspapers, magazines and books, deposit articles and shopping bags are excluded from the rewards with miles for legal reasons.
The HEINEMANN delivery service is available for customers who have a valid EU flight with a departure date within the next three months from the date of the order and a valid delivery address in Germany.


text:
US Power and the New Course Towards War
We live, and have been living, in an epoch of capitalist decadence. Notwithstanding longer life expectancy, technological advance, and the claims of its defenders, the capitalist system is incapable of addressing existential questions such as the destruction of the environment via man-made climate change. After all, to do so would get in the way of making profits. Short-term expediency portends long term disaster.
John McCain – War Hero or Racist War Monger?
The publicity surrounding John McCain's recent funeral was excessive to say the least, with wall-to-wall coverage in the United States and Britain, as well as other countries around the world. We were relentlessly informed in a slew of whitewashed obituaries, cringe-worthy plaudits and declarations of love from the bourgeoisie on both sides of the Atlantic for more than a week, in newspapers, online and on television, what a heroic champion of freedom, democracy, civil rights and free speech this man was; as well as being above all a great patriot.
No War But the Class War
Yemen's "Forgotten War" Re-ignited
Against Nationalism and War!
Protest without illusions
Yeryüzü Postası respond to the assault on Afrin
A way ahead for a new peace movement
The first pamphlet published by the Scottish Solidarity group in June 1966 about the anti-war and antinuclear weapons movements.


text:
The ThermoBaby bottle heater will quickly heat both the milk bottle and baby food and help keep it at the right temperature.In addition, you can also thaw the baby food with this handy device. Suitable for all the most popular food bottles.
Even though you could keep your baby's milk bottle or food store hot under hot water, in the microwave or on a hot stove, it's not sensible, time-saving or safe. ThermoBaby makes both the heating of the milk and the melting and heating of the food for you so that you can focus on your child at that time. And if the baby stops slightly longer, the device keeps the food warm for some time.
The ThermoBaby Bottom and Baby Heating Heater is a three-in-one device with many benefits.
1.Insure the milk evenly and quickly.
2. The device has three energy-saving modes.
3. The baby bottle and baby food heater is safe - it has an automatic shut-off mode.
4. The developer of the device is a long-established European manufacturer of medical accessories Ca-Mi, whose hit product is the KIWI inhaler - the favorite of mothers and children in Estonia. Therefore, the product has a lot of emphasis on design and ease of use!
In spite of its efficiency, the ThemroBaby handkerchief and baby food heater are small enough - its dimensions are 16x15x14.5 cm and weighs only 0.5 kg.
The ThermoBaby warranty period is 24 months.
Manufacturer: Ca-Mi, Italy
Delivery Policy:
Orders will be processed and, if applicable, orders will be shipped within 1-3 working days (depends on area). Estimated delivery times after order confirmation by merchant bare displayed below however.
In certain countries, products may not be shipped to PO Box addresses and merchant assumes no liability for failed deliveries caused by incorrect addresses, absence of the recipient, customs issues or force majeure.
Estimated delivery times (after order confirmation):
Estonia: Parcel Terminals 1-2 working days; Courier 1 working day (home or office)
Latvia: Parcel Terminals 2-3 working days; Courier 2 working days(home or office)
Lithuania: Parcel Terminals 2-3 working days; Courier 2 working days (home or office)
Finland: Parcel Terminals in Helsinki 1-3 working days; Parcel Terminals in the rest of Finland 3-5 working days; Courier 2 working days (home or office)
Return Policy:
Unused products can be returned in accordance with the applicable terms and conditions in original packaging within 14 days of receipt. Products returned thereafter can no longer be considered for refund or exchange nor can PINS be refunded unless specified otherwise. In order to return your reward, please contact customer service to declare return and have your PINS or PINS & cash (only if applicable) refunded. In case of physically damaged products shipped via UPS, FedEx, or other courier services, you may refuse delivery. Any damage found after opening your packages and examining the merchandise should be reported to the relevant courier service and the merchant within 48 hours after delivery in order to start the replacement or repair process. If you receive damaged merchandise, always keep the shipping cartons and documents until your claim has been acknowledged and settled. For additional information regarding product specific warranties and replacements please refer to the general terms and conditions.


text:
Jeri Jacquin
In theatres this Friday from director Ron Howard based on the books from author Dan Brown with Imagine Entertainment and Columbia Pictures is INFERNO.
Robert Langdon (Tom Hanks) returns but this time in fog and in Italy. In the hospital he meets Dr. Sienna Brooke (Felicity Jones) who is treating him for a gunshot wound to the head. It doesn't take long before he realizes where he is and that someone is trying to kill him.
Dr. Brooke and Langdon are on the run being chased by a crazed cop but they aren't the only ones chasing. The W.H.O.'s Elizabeth Sinskey (Sidse Babett Knudsen) is on the chase up against Christoph Bouchard (Omary Sy) and these two are not friends.
Starting out with the clues leading to Dante himself, the two are racing against the clock when they discover that Bertrand Zobrist (Ben Foster) is prepared to release a virus. His intention is to clear the globe of overpopulation. Enter Harry Sims (Irrfan Khan), another mysterious chaser who may hold the final piece of the puzzle.
Once again Langdon is out of time!
Hanks as Langdon has solidified his status as this character and there are traits that have popped up from film to film. An example is when he stares at something followed by talking to himself until his eyes are roaming fast like his brain is the actual inferno. This time he has no idea who to trust because even though his historical memory is in tact, who is who in past days – not so much.
Jones as Dr. Brooke goes along for the chase and already knows the famous Dr. Langdon. In this role Jones 'goes along to get along' following Langdon keeping an eye on her patient. Sy as Bouchard wants what he thinks Langdon has and that makes for one gun toting batch of meanness.
Zobrist as Foster is brief but the reason for the entire viral chaos. His story comes in pieces yet every time he is on screen I'm happy about it. Khan as Sims has the opportunity to break away from the pack with his focus on business and mixture of shocking humor.
Knudsen as Elizabeth will always win in my book. If you haven't seen the television series Borgen then you are truly missing the extent of what this actress can do. She has a range that had me hating when Borgen wrapped up but thrilled to see her return on the HBO series Westworld.
Extended cast include Ana Ularu as Vayentha, Ida Darvish as Marta Alvarez, Paolo Simioni as Dr. Marconi, and Fausto Sciarappa as Parker.
TUBS OF POPCORN: I give INFERNO three and a half tubs of popcorn out of five. This is another installment in the Dan Brown series of Da Vinci Code books and I looked forward to seeing it. I don't know whether I'm just turning into Langdon myself (which is very cool) because I did figure out several things and I'm keeping it to myself. This is a complete no-spoiler zone when it comes to anything Hanks!
Foster looked amazing but then again he always does and Khan gets the amazing opportunity to bring humor to a dire situation yet I loved it. Both of these actors are high on my list of must-see in everything they do because they are so diverse. I don't mind being partial as Tom Hanks will win at everything he does because he is has become an icon in a way that is rare and pretty dang cool.
The tour of Europe and its stunning treasures but then again Academy Award winning director Ron Howard wouldn't have it any other way I'm sure. Author Dan Brown has grabbed book lover's attention since the 2006 release of The Da Vinci Code and it's follow up of Angels & Demons in 2009. Now, if anyone is curious, The Lost Symbol is next on the list of books that I'm sure will have us all waiting for screen.
In the end – his greatest challenge and humanity's last hope!


text:
Whether it's smart wearables, connected cars and machines, consumer electronics or smart city deployments, there is no denying the internet of things is growing at an increasingly rapid rate. However, yielding this opportunity in the correct way to create true value for enterprise and consumers while ensuring a safe and secure experience does not come without challenges. Addressing these is not something that device providers, service providers or application developers can ignore in their IoT strategies — but there is a solution.
The technical and commercial success of cloud computing technology made it feasible to evolve the most demanding information and communication technology (ICT) infrastructures, such as communication networks, from specialized hardware and software to new software paradigms, referred to as 'cloud-native'. Internet of Things (IoT) virtualization – IoT built on cloud-native principles – is to IoT platforms what Network Function Virtualization (NFV) is to communication networks.
Smart Cities will be built on a combination of infrastructure from players, including telecoms operators, mobility operators, public safety agencies, and utilities, as well as infrastructure from cities themselves, cities that will run different legacy and platform-based IoT deployments. It is widely acknowledged that no single IoT platform will dominate the market. Here we see the increasing need for IoT platforms to exchange data to address the requirements of cross-application use cases. This will only be achieved by IoT platforms designed and managed for interoperability.
Matching Providers


text:
[lgc_column grid="50″ tablet_grid="50″ mobile_grid="100″ last="false"]
Siggy and Zultroy ,the long estranged founding member of Siggy and Starlites, have come together, and are currently working on new material, Songs for Peace.
In the days leading up to the trial on Ginga, both political factions are taking sides, and it appears Ronkle is preparing for martial law, while Groody continues to be the harbinger of peace that Gorgan preached during his reign on Ginga.
Gorgs are taking sides, and the battle lines are being drawn. Siggy and Zultroy have apparently chosen Groody's side of peaceful resolution, but not all Gorgs are happy with them getting involved in their planetary politics. [/lgc_column]
[lgc_column grid="50″ tablet_grid="50″ mobile_grid="100″ last="true"]
"Siggy and Zultroy should mind their own business. The Sig-Metro Trance Bar is a dump, and they haven't had a hit since Sluglife…go crawl or slime your way back into the decayed log your kind crawled out from under!"
– Anonymous Ronkle Sympathizer
But there is plenty of support for the power musical duo as well.
"I think it is great to see Siggy and Zultroy together, and I'm sure whatever they come up with will be awesome. But, I am a little disappointed that Lordy Blick isn't involved in this project. He's so dreamy!"
– A Gorgling fan of the musicians.
Editors Note: Tour Manager for Lordy Blick told GGP that the former member of the original Starlites band is currently touring in Vidogo with his band the Two Tones, but fully supports Siggy and Zultroy's peace efforts.


text:
Strong performances by ORICA-GreenEDGE at the Boucles Drome ArdecheSun 28 Feb 2016
2015 Classica San Sebastian winner Adam Yates has finished in the top ten for the second time in two days, placing sixth at La Drome Classic after another day of fast and aggressive racing in the Ardeche region of France.
The race was won by Czech champion Petr Vakoc (Etixx-Quickstep), claiming his second victory of the weekend at the Boucles Drome Ardeche.
Sports Director Dave McPartland was pleased with the team's performace over the two races.
"We can be very satisfied with our performances here over the weekend," McPartland said. "We raced solidly as a team and Adam was unfortunate again today not to make it onto the podium."
"It was another fast and quite stressful start to the race on small roads which settled down once the break had gotten away. The peloton sat on for the first 100 kilometres or so and the race really got going for us with about 50 kilometres to go."
In what was almost a carbon copy scenario of the previous day's race, Yates was in an excellent position approaching the finish with a familiar group of riders.
"We set Adam up really well going into the final climb and he was in a strong position, but just got edged out on the slight to descent to the finish line," McPartland continued.
"The team were very controlled throughout and we can build on the positives from these races."
How it happened:
A cold morning in Livron welcomed the riders to the start line for what proved to be a consecutive day of fast racing with average speeds consistently over 43 kph. The early breakaway formed with four riders, quickly gaining a lead of over four minutes on the peloton.
The main group remained calm and the race was relatively uneventful approaching the 50 kilometres to go marker. Etixx-Quickstep started to take control of the race and the gap to the leaders began to fall significantly, standing at one minute and thirty seconds at the start of the last lap.
Once the breakaway had been caught the attacks started to come thick and fast. Romain Bardet (AG2R) and Gianluca Brambilla (Etixx-Quickstep) attempted a move that didn't hold with around 15 kilometres to go. Almost as soon as the duo had been caught Jan Bakelants (AG2R) decided to make a bid for glory in the last five kilometres but the front group came together and reeled him in.
The last climb of the day was right on the doorstep of the finish and the right move here proved to be decisive. ORICA-GreenEDGE were together going into the climb and put Yates into an excellent position amongst the front runners.
Vakoc (Etixx-Quicktep) and Bakelants (AG2R) attacked on the descent and gained a valuable few metres on the rest of the leaders. Vakoc held on to take the win with Bakelants coming in second and Arthur Vichot (FDJ) taking the final podium spot with Yates finishing closely behind in sixth place.
The next race for ORICA-GreenEDGE is Strade Bianche in Italy on Saturday the 5th of March.
La Drome Classic results:
1. Petr Vakoc (Etixx-Quickstep) 5:08:57
2. Jan Bakelants (AG2R) ST
3. Arthur Vichot (FDJ) +6sec
6. Adam Yates (OGE) +6sec


text:
The Black-Greens Have Lost Points in Snowy Khimki
FC Dynamo Moscow 1-1 (0-0) FC Krasnodar
Goals: Markov, 77 (Joãozinho, 1-0), Wanderson, 87 (1-1).
FC Dynamo Moscow: Shunin, Morozov (Holmén, 78), Šunjić, Yevgenyev, Kozlov, Yusupov, Sow, Černych (Grulyov, 60), Joãozinho, Markov, Lutsenko.
FC Krasnodar: Safonov, Stotsky, Spajić, Martynovich, Skopintsev (Ramírez, 76), Kaboré (Utkin, 66), Gazinsky, Pereyra, Wanderson, Suleymanov (Ignatyev, 46), Claesson.
Yellow cards: Markov, 36 (foul play), Lutsenko, 43 (foul play), Sow, 83 (attack breakdown) – Kaboré, 25 (foul play), Wanderson, 41 (foul play).
Referees: Turbin (Moscow), Bolkhovitin (Leningrad Oblast), Kudryavtsev (Saint Petersburg).
14 April 2019. Khimki. Arena Khimki Stadium. Occasional snow. 4 degrees. 5 873 spectators.
The match staged at the Arena Khimki in cold, snowy weather did not display too much praiseworthy action, and scoring chances were not that frequent either. An opener was scored on the 77th minute by the FC Dynamo player Yevgeni Markov, who took an accurate header making good use of a expert serve that ex-Krasnodar Joãozinho had provided him with after a corner kick. The Bulls scored an equalizing goal ten minutes later. Wanderson Maciel finished the ball sending it into the home team's net after Pereyra's shot that had hit a goalpost with a rebound. A few moments to a full-time the black-greens came just short of snatching the win away. Unfortunately for them Shunin saved his team when he parried a header by Claesson at close range. As a result, FC Krasnodar lost both points and the second position in the standings that is now occupied by FC Lokomotiv Moscow.


text:
Honda targets Guinness World Records attempt for fuel efficiency
29/05/2015 06:46
Honda targets Guinness World Records attempt for fuel efficiency
Honda is set to put the real-world fuel economy of its 1.6 i-DTEC engine to the test in an 8,500-mile drive across all 24 contiguous EU countries. In doing so, the carmaker aims to set the benchmark for a new Guinness World Records title in fuel efficiency.
On Monday 1 June, two members of Honda's European Research and Development (R&D) team will set out on an epic journey from Aalst, Belgium in a Honda Civic Tourer. Heading towards the Netherlands and Germany, their trip will see them navigate the Continent in a clockwise direction, with the aim of returning to their starting point some 25 days later, on June 25, having covered a total of 8,459miles.
The title attempt never attempted in Europe follows several independent tests, which have proven Honda's 1.6 i-DTEC engine to consistently out-perform its quoted fuel efficiency in real-world driving conditions.
Under the rules of the Guinness World Records title attempt, the same two drivers colleagues Julian Warren and Fergal McGarth must be in the car for every kilometre of the journey. Based at Honda's European manufacturing facility in Swindon, UK, the pair volunteered to take up the challenge and will be charged with driving an average of 370 miles (7.5 hours) each day.
Fergal McGrath said: "We are very much looking forward to the record attempt, and while we're excited we're both a little nervous about the scale of the task that awaits us. A huge amount of planning has gone into taking on this challenge and we look forward to what we hope will be a successful result when we return to Brussels on June 25th. But we've got more than 170 hours behind the wheel to contend with first!"
The official Guinness World Records title is 'Lowest Fuel Consumption all 24 contiguous EU countries', measured in litres per 100km and miles per gallon calculated over the entire journey. If successful, the new record will apply to all cars, including hybrid and electric models.
Based on strict and rigorous guidelines, the record attempt requires the car to enter each of the 24 countries specified, collecting a range of evidence including a fuel/mileage logbook, GPS readings, video, photographs and independent witness signatures to prove that it has done so.
Philip Crossman, managing director of Honda UK, added: "Since its launch in 2013 we have seen the 1.6 i-DTEC engine consistently over-perform on real-world fuel efficiency in our Civic, Civic Tourer and CR-V models, and this is our opportunity to put it to the ultimate test on a huge scale. We are very confident of a great result and we wish the team all the very best of luck as they take on the challenge."
Supporters will be able to follow the progression of the two drivers live by visiting http://www.tracker.co.uk/RealFuelChallenge.
by: Sophie Williamson-Stothert