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One of my strategies to eating around New York on an indispensible budget is to do lunch well – especially if the dinner entrees of a desired restaurant tend to hit a higher price point. Lincoln, however, was not to fall under that game plan. Sam Kim said, "It's THE opening of Fall [2010]." So I secured a reservation three weeks prior to opening and four before I boarded for JFK. It is a special place that, upon approach and even closer look, was designed to seamlessly blend into Lincoln Center. It is successful, indeed – etymologically and aesthetically, inside and out. It's a masterpiece complete with a sloped, grass-covered roof that doubles as a lawn.
I had two dinner companions, and we all agreed that the feel of the space was uniquely pleasant. Beautiful. "It's like how an airport is supposed to feel," my friend Robbie said. The pristine, glass-encased kitchen highlighted the excellent service we received all night in an impeccably casual, yet elegant, ambiance. Through the glass walls, I admired Jonathan Benno – previously Chef de Cuisine at Per Se for 6 years – as he sent out each dish. The servers' pace was expedient but never hurried.
We were artfully presented with thin crisps – seasoned with things delightful and elusive to my memory – before a perfect selection of three varieties of bread. The butter, made with 83% Vermont buttercream, was some of the best I have ever had. Our appetizer, a perfectly seared sea scallop with almonds and sunchoke smear, was a delicious departure and made me excited for more.


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A.W. Hastings Field Marketing Manager Beth Gendron shares highlights from Hastings' first all female marketing trip to Marvin headquarters in Warroad, MN.
Many of my Hastings colleagues have been to the Marvin factory in Warroad, MN numerous times, and they always come back with great stories to tell. So I was excited recently to have my first opportunity to co–host (along with Hastings' Cindy Breheny) a retailer trip to the Marvin factory in Warroad, MN. This trip was even more special because it was Hastings' first ever all female marketing trip.
Many of our attendees had never had the opportunity to visit the Marvin factory, and our goal was to leave them with the "wow" factor that everyone has when visiting Marvin for the first time! We accomplished that and more, because even better, we were able to share so many great ideas and conversations on a professional and personal level during the trip.
Our trip started with a stop in Minneapolis, where we toured the Walker Sculpture Park and experienced the iconic cherry and spoon and the heart of the park system in Minneapolis. Then, it was on to a private tour of the Purcell-Cutts House. The next day, we visited the corporate marketing office in Eagan to get a behind the scenes look at their marketing operations, and then it was off to Warroad on Marvin's private plane. When we arrived in Warroad, we met up with our tour guide, Elena, and started our factory tour of wood processing before finishing up with the museum tour. The highlight of the tour for many was the Marvin museum, and it was touching in so many ways as several of these women are part of a family owned business and are owners themselves.
I know that our attendees on this unique trip to Marvin were left with a new appreciation of Marvin and the craftsmanship and values that the Marvin family is committed to. Many of the marketing managers/owners could also relate to the Marvin family and were inspired by their story, which was so great to see.
Here are just a few of the comments I received in post-trip thank you notes. "Our trip was rewarding in the people and places we met, especially learning about and understanding the care and attention Marvin gives to its brands, products, services, its employees, its community and its customers." – Joan Brooks, Harbrook Fine Windows, Doors & Hardware
"The trip to Minneapolis and Warroad was terrific and so well organized. I am so glad I decided to go. Thanks to all the Hastings and Marvin people who made the trip interesting and comfortable. I have returned with greater enthusiasm for Marvin products, a renewed appreciation for American ingenuity and the importance of community." – Allison Neumann, Ed Herrington, Inc.
"As always, the trip was well planned and you all did a fantastic job catering to the group. It was a good 'reMarvinization' for me to spend some time in Warroad and I also really enjoyed visiting the Guthrie, which I've heard so much about." – April Bolin, Windows & Doors By Brownell
During the trip, we shared a lot of laughs and all of us connected on a more personal level. Our first night at dinner, the waitress at the restaurant asked us if we were a sorority that was reuniting …. That just goes to show the connections that were being formed a few short hours into the trip!
All of the attendees left with a renewed appreciation for American made products, family business values, the importance of their community, and most importantly the care and attention Marvin gives to their customers. Thanks to everyone who attended and to Cindy for all her help and guidance in planning this trip – an experience I will never forget!

subset: commoncrawl


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ICMP presents: The Artist's Journey: Songs and sonic identities
Senior A&R, Imagem Music
Ed is the Senior A&R for Imagem Music, a modern music publisher that represent artists and writers such as Daft Punk, Mark Ronson, Bombay Bicycle Club, Oh Wonder and Cathy Dennis. He has 15 years experience in music, developing artists and songwriters.
Previously he headed up A&R at Glassnote UK working with artists such as Aurora, James Hersey and Tor Miller, as well as songwriters such as Jonny Wright and O. Martin. Before joining Glassnote, Ed worked at BMI as Executive, Writer-Publisher Relations for UK and Europe, bringing in Ed Sheeran, Gotye, Avicii, Ellie Goulding, Example and Nero to the company. His previous experience also includes working for Kobalt Music Group and founding the widely used A&R tipping site TheLiveList.
Follow Ed Poston - Imagem Music on:
Site design & build by View Creative Agency


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Simulator Sickness
I feel like my tolerance for becoming nauseated while gaming has been going downhill to the point where I should try to do something about it. Background information:
- I primarily play on my living room HTPC with an 85" front projector ~15 ft away at eye level. I usually sit offset from center by about 4 ft.
- I have no problem with TF2, Portal, KSP, Dust, EVE, Unreal 2k4, Overwatch, Skyrim, Battlefield (any), or MechWarrior (any).
- I have never been able to play the original Half Life for more than 15 minutes at a time on any computer/setup I've ever owned. Unreal Alpha, Fallout 4, Obduction, and the PC version of Beyond Good and Evil all make me sick in less than an hour.
- I don't ordinarily get sick while playing console games but recently felt ill after watching friends play Twilight Princess on their TV.
- Handhelds don't give me any trouble.
I've been thinking about getting a SHIELD or some sort of handheld streaming device since I don't own another TV/monitor and don't have a desk. I'm also worried that VR is going to suck for me.
Do any of y'all have similar responses and what are good solutions for you? Any other suggestions?
@drasnor I got an HTC VIVE and tried War Thunder the flight sim on it... I cant do flight sims in vr and its a whole you're moving or tilting in game and your body isnt but it should, and it just... it made almost puke. its probably something on that level of why with simulators might throw you off.
there's also something to be said for watching and not playing, theres a disconnect and a level of not being in control that might throw you or anyone off.
you could also adjust fov/motion blur/occlusion to try and help with other games and game types to see if that helps. a steady refresh/frame rate would also cut it down0
drasnor Starship Operator Hawthorne, CA
@DontCallMeKelso said:
you could also adjust fov/motion blur/occlusion to try and help with other games and game types to see if that helps. a steady refresh/frame rate would also cut it down
I try lots of different FOVs but haven't really found one that works for me in the ones that make me sick. I always turn off motion blur and view bob; I'll have to look into occlusion as that's a new one for me. I have VSync turned on as well; not sure if that addresses the framerate.0
Massalinie _k's Waifu Texas
I'm generally not sensitive to this sort of thing myself but I know others who are sensitive to motion sickness from things like 3D movies also find VR to be nauseating. I have experienced nausea from VR, it's usually because of sensory mismatch. For example in a 360 degree image, you can turn your head and look around but if you try to tilt or lean nothing happens so when you do those things most senses are telling your brain one thing and your vision is getting something else which causes the nausea; it's the same reason I got motion sickness in boats. Low framerates can have the same effect. If you move your head and the image doesn't keep up, so to speak, it can make you nauseous, especially if you're sensitive to that sort of thing to begin with. I also don't like it if the image isn't crisp and clear, my eyes keep trying to focus but can't and that can be bad. Then I've heard there can be problems any time the game takes control of the camera for you too, so you might want to stay away from things like roller coaster simulators at first. I have also only tried the Oculus though which is pretty clunky for adjusting the focus through the lenses so I wonder if maybe the Vive or Sony one are better in that regard.
Basically if the game is handling the VR well, you might be fine, but I also suspect that some people are just too sensitive to it. It's difficult to get people who have been nauseous from VR before to keep trying it though, especially at work (because who wants to be nauseous at work?). One of my VR-nausea people at work tried the AR in the HoloLens and didn't report any nausea, even when it was obscuring their vision as fully as it could so I wonder if having that little bit of peripheral vision makes a difference.0


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Today is Opening Day in Milwaukee. Here is my photograph of Opening Day, 1999 at Milwaukee County Stadium. Don't forget (shameless plug) this 18 x 24 print is available for only28.00 shipping included. A great Fathers Day gift !
Friday, April 4, 2008
2 comments:
- Jason said...
Hey David I love this picture and i tried ordering it from inside wisconsin sports gifts with no response. Do you sell prints of your pictures?
- July 29, 2010 at 11:17 AM
- Alexandra Fedie said...
David - Do you still have this print for sale? I would love to purchase one, possibly two from you. Please contact me at firstname.lastname@example.com. Thank you!
- July 17, 2012 at 8:25 PM
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BOSTON (MarketWatch) -- Barclays Global Investors, a unit of British bank Barclays PLC BCS, +7.27%, has filed an initial prospectus with the SEC for an exchange-traded fund tracking the Russell Microcap Index. The Russell index is set to be launched on June 24. If approved, the fund would track about 3% of the market capitalization of the U.S. stock market, and would be the first micro-cap ETF.
Barclays files for micro-cap ETF on new Russell index
Quote References
+0.66 +7.27%


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8th March 2017
Written on 6th March 2017
TAG Global Touring goes behind the scenes on the Justin Bieber Purpose World Tour
For those who have been living under a rock for the last 12 month, Justin Bieber sailed through 2016 hitting record after record and selling a countless number of albums. Even his usual detractors could not deny the album "Purpose" was a stroke of genius and unsurprisingly, took the world by storm.
Announced on 11th November 2015 on the Ellen DeGeneres show, the Purpose World Tour was to be the third worldwide tour by the Canadian singer, in support of his fourth studio album of the same name, released that same month.
The Tour started on the 9th March 2016 in Seattle and is scheduled to end on the 6th September 2017 in Toronto. Over the 18 month period, the show will have be performed in six continents, with a total of 164 dates: 73 in North America, 64 in Europe, 15 in Latin America, five in Oceania and two in Africa.
Chris Gratton, Production Manager of the tour, was the brains behind this huge operation. It was Chris who initially approached The Appointment Group (TAG) Los Angeles to arrange all of the travel logistics for the North American leg of the tour. Having collaborated previously on the Ariana Grande tour he was overseeing, it seemed a natural progression that we were entrusted to handle the logistics of this incredibly challenging project. In February last year, our UK operation was also contacted, this time to commence work on the European leg of the tour. We were charged with looking after several travelling parties including the band, dancers and production crews.
Work began immediately to source the European hotel requirements, which required a great amount of work and attention, due to the scale of the tour.
Rachel Gosling, Operations Manager of TAG Global Touring comments: "One of the main challenges we face with tours of this scale is availability. Many of the cities can already have large scale events in place that have a huge impact on the availability of accommodation. This is where our relations with our preferred suppliers are of paramount importance. Due to our trusted, long-standing relationships with these suppliers we are capable of sourcing the right types of accommodation, meeting the pre-defined criteria of star rating, location and budget"
With a total of 64 different hotel bookings throughout the European leg of the tour and with a travelling party totalling 104 people, this was a very tricky project to manage. Furthermore, both scheduled and private air charters were sourced to accommodate the groups for the entire length of the tour. Considering the degree of complexity and length of the tour, TAG Global Touring offered Chris Gratton and his Production Coordinator, Jessica Sheehan the use of the TAG Global Touring App.
Rachel Gosling adds: "Our ground-breaking Global Touring App software was made available to Chris Gratton and Jessica Sheehan offering them an accessible, round the clock high-tech solution whilst travelling out on the road. This is particularly crucial for a tour of this size given that the App is able to display up-to-date information at all hours of the day at the click of a button, making it much easier to keep a close eye over all of the travel arrangements. TAG Global Touring also implemented an experienced team member, Tiffany Cathcart, to travel with the group. During the tour Tiffany provided full, dedicated support to the party whilst out on the road. Tiffany travelled ahead of the group and liaised with all hotels to ensure they were fully prepared for their arrival to enable all check ins to be a smooth, seamless process. Furthermore, her duties included handling any late changes, being onsite to supervise the group check in process in all cities and generally ensuring that everything was in place to relieve Chris and Jessica of any unwanted travel challenges that may arise. This was all backed-up by our dedicated 24/7 emergency team who are always on hand for all of our clientele."
On the 29th November the final concert of the 2016 European tour was held at the O2 Arena in London. However, with the unstoppable Purpose tour back out on the road for 2017, we continue to work with Chris and his team on this fantastic, marathon-like production. Rachel adds: "Being so heavily involved in such an incredible tour was a tremendous opportunity. It is a privilege to continue to work with Chris and Jessica and we have loved being a key part of such a fantastic tour and production."
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WOW!!! This post marks my 100th blog post! Thanks to everyone that visits, reads and shares my blog. I hope that I can inspire and help you to create beautiful projects too!
Right from my early crafting days (around age 17) I remember taking photos and well back then (1996) you just had your photos actually printed! I still have all those photos in an album. So in a way I was blogging/pinteresting even then! The old way at least.
Blogging is such a great way for me to share with you all my crafty projects. I can pretty much blog anywhere I go! While I'm on the train, in the car waiting for kinder to finish, during my lunch breaks - anywhere its really cool.
To help celebrate this milestone here's a quick 'Congrats' card I recently made for my Bestie who has just moved into her own home.
Stampin' Up! Supplies


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2019 Board Leadership Providence Portland Medical Foundation
F. Michael Nugent
Gayland Looney
Kristi Richards
Tayo T. Akanni
Members Providence Portland Medical Foundation
Shaghayegh Aliabadi-Wahle, M.D.
Arlene Austinson
Arleen Barnett
R. Bryan Bell, M.D., D.D.S.
Mary Chen
Katie B. Foehl
Dan Ford
Andy Gibson
Ellen S. Gyllstrom
Bradley Jenkins
Art Johnson
Nick Kassab
William Kennedy
Paul Labby
Nancy C. Lematta
Jack R. Loacker
Erin Miller
Ernie Platt
Bruce Schoen
Sarah Slaughter, M.D.
Ex-Officio Members Providence Portland Medical Foundation
Krista Farnham
Chief Executive, Providence Portland Medical Center and Eastern Oregon Region
Dan T. Floyd
Leadership Cabinet Liaison
Walter J. Urba, M.D., Ph.D.
Director, Earle A. Chiles Research Institute, Providence Cancer Center


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Why teach mathematics?
"Mathematics is a creative and highly interconnected discipline that has been developed over centuries, providing the solution to some of history's most intriguing problems. It is essential to everyday life, critical to science, technology and engineering, and necessary for financial literacy and all forms of employment. A high-quality education in maths therefore provides a foundation for understanding the world, the ability to reason mathematically, an appreciation of the beauty and power of mathematics, and a sense of enjoyment and curiosity about the subject."
National Curriculum in England, 2014
Fluency, Reasoning and Problem Solving
We follow the National Curriculum aims for mathematics, which are to ensure that all pupils:
- become fluent in the fundamentals of mathematics, including through varied and frequent practise with increasingly complex problems over time, so that pupils develop conceptual understanding and the ability to recall and apply knowledge rapidly and accurately;
- reason mathematically by following a line of enquiry, conjecturing relationships and generalisations, and developing an argument, justification or proof using mathematical language;
- can solve problems by applying their mathematics to a variety of routine and non-routine problems with increasing sophistication, including breaking down problems into a series of simpler steps and persevering in seeking solutions.
Fluency development is developing pupil's understanding of mathematical concepts and skills, how they link and how they 'work', in order for pupils to be competent and confident in using a variety of mathematical strategies and approaches independently. It is developed through regular discussion about strategies and methods, a recognition and understanding that there is not one right way of solving a calculation or problem, and regular arithmetic practice (Maths of the Day, arithmetic sessions in Key Stage Two, Times Table practice particularly in lower Key Stage Two).
Reasoning development is developing pupil's language and ability to discuss and explain their strategies, solutions and approaches to mathematical activities. It is developed through regular opportunities to reason verbally and in writing, the use and modelling of high quality mathematical language, the use of diagrams, manipulatives and calculations to support and structure pupil's reasoning, and the use of a variety of questions, such as Why? Why not? What if? How?
Pupils across the school use APE as a strategy to structure their verbal and written reasoning. This strategy is adapted to suit the age of the pupils, and the detail and complexity of the reasoning increases through the year groups.
A= Answer. What is the answer to the question, problem or discussion prompt?
P= Prove. How do you know that the answer is correct? Explain with pictures, diagrams, calculations, manipulatives, sentences or in another way.
E= Explain. Explain their approach, strategies and thinking.
Problem Solving:
Problem Solving within mathematics refers to activities and experiences where maths is used and applied, where there is more than a simple, straightforward calculation, and where mathematical thinking is required. A variety of skills need to be developed in order for pupils to be successful in solving problems, such as:
- selecting appropriate resources, posing and answering questions,
- representing problems using symbols, words, diagrams or pictures, developing and choosing ways to record,
- predicting,
- making connections,
- concluding and explaining,
- identifying patterns,
- forming generalisations in words, pictures or with resources,
- justifying answers, solutions, methods and conclusions and supporting with examples,
- organising work, working systematically and checking results.
Foundation Stage
All pupils are given ample opportunity to develop their understanding of mathematics through varied activities that allow pupils to use, enjoy, explore, practice and talk confidently about mathematics. Mathematics teaching and learning in Foundation Stage involves providing pupils with opportunities to develop and improve their skills in counting, understanding and using numbers, calculating simple addition and subtraction problems; and describing shape, spaces and measures.
Key Stage One
The principal focus of mathematics teaching in Key Stage 1 is to ensure that pupils develop confidence and mental fluency with whole numbers, counting and place value. This should involve working with numerals, words and the four operations, including with practical resources (e.g. concrete objects and measuring tools). At this stage, pupils should develop their ability to recognise, describe, draw, compare and sort different shapes and use the related vocabulary. Teaching should also involve using a range of measures to describe and compare different quantities such as length, mass, capacity/volume, time and money. By the end of Year 2, pupils should know the number bonds to 20 and be precise in using and understanding place value. An emphasis on practice at this early stage will aid fluency. Pupils should read and spell mathematical vocabulary, at a level consistent with their increasing word reading and spelling knowledge at Key Stage 1.
National Curriculum in England, 2014
Lower Key Stage Two
The principal focus of mathematics teaching in lower Key Stage 2 is to ensure that pupils become increasingly fluent with whole numbers and the four operations, including number facts and the concept of place value. This should ensure that pupils develop efficient written and mental methods and perform calculations accurately with increasingly large whole numbers. At this stage, pupils should develop their ability to solve a range of problems, including with simple fractions and decimal place value. Teaching should also ensure that pupils draw with increasing accuracy and develop mathematical reasoning so they can analyse shapes and their properties, and confidently describe the relationships between them. It should ensure that they can use measuring instruments with accuracy and make connections between measure and number. By the end of Year 4, pupils should have memorised their multiplication tables up to and including the 12 multiplication table and show precision and fluency in their work. Pupils should read and spell mathematical vocabulary correctly and confidently, using their growing word reading knowledge and their knowledge of spelling.
National Curriculum in England, 2014
Upper Key Stage Two
The principal focus of mathematics teaching in upper Key Stage 2 is to ensure that pupils extend their understanding of the number system and place value to include larger integers. This should develop the connections that pupils make between multiplication and division with fractions, decimals, percentages and ratio. At this stage, pupils should develop their ability to solve a wider range of problems, including increasingly complex properties of numbers and arithmetic, and problems demanding efficient written and mental methods of calculation. With this foundation in arithmetic, pupils are introduced to the language of algebra as a means for solving a variety of problems. Teaching in geometry and measures should consolidate and extend knowledge developed in number. Teaching should also ensure that pupils classify shapes with increasingly complex geometric properties and that they learn the vocabulary they need to describe them. By the end of Year 6, pupils should be fluent in written methods for all four operations, including long multiplication and division, and in working with fractions, decimals and percentages. Pupils should read, spell and pronounce mathematical vocabulary correctly.
National Curriculum in England, 2014
Calculation Strategies
Pupils are encouraged to develop and use a variety of formal and informal methods for recording their mathematical learning, appropriate to their age. Pupils are encouraged to compare and discuss different methods, and are supported in choosing an appropriate and effective strategy for the activity. Mental mathematics and arithmetic are incorporated throughout all lessons and mental calculation strategies are discussed and developed continuously. A secure foundation in mental calculation, mental strategies and recall of number facts is established, before written strategies and methods are introduced.
In order for pupils to understand and reason why concepts, approaches and strategies are true and effective, pupil's conceptual understanding is developed alongside their understanding of how strategies and concepts work. Pupils are taught new strategies using CPA approach (concrete, pictorial, abstract). This means that pupils will first use a strategy or method with concrete resources and manipulatives (such as dienes, counters or cubes), then pictorially (such as diagrams, bar model or pictures of manipulatives), and finally in their head or on paper.
Our calculation policy is currently being updated and a parent's guide will be available here soon.
Resources and Manipulatives
A wide range of resources and manipulatives are used throughout the school to develop understanding. All pupils are encouraged to use these to support their learning, and each class has similar resources to ensure progression, consistency and continuity.
Multilink Cubes
Place Value Counters
Dienes or Base Ten
Bead Strings
Tens frame
Hundred Square
Multiplication Square
Number Line
Cuisenaire Rods
Mathematics at Home
Each child in years 2-6 has an individual login to Times Tables Rockstars, a website designed to support the development of multiplication facts.
Other useful websites may be:
Useful documents for ways in which you can help your child at home:
Equal Opportunities
Positive attitudes towards mathematics are encouraged so that all pupils, regardless of race, gender, cultural background, ability, SEN or disability, including those for whom English is an additional language, develop an enjoyment and confidence within mathematics. All pupils receive high quality inclusive teaching, and high expectations are set for all.
A mastery approach is used within mathematics teaching and learning at St. Michael's. A mindset that all are able to achieve is adopted by all adults and continually developed within pupils through the use of mixed ability flexible groupings and collaboration; the careful planning of tasks and activities; opportunities for pupils to reflect on their learning and understanding and choose their task, approach or resource; and the use of manipulatives for all pupils and abilities.
"The expectation is that the majority of pupils will move through the programmes of study at broadly the same pace. However, decisions about when to progress should always be based on the security of pupils' understanding and their readiness to progress to the next stage. Pupils who grasp concepts rapidly should be challenged through being offered rich and sophisticated problems before any acceleration through new content. Those who are not sufficiently fluent with earlier material should consolidate their understanding, including through additional practice, before moving on."
National Curriculum in England, 2014
Class teachers provide appropriately differentiated activities to ensure all pupils are challenged at an appropriate level for their current learning. Teachers use a variety of differentiation strategies, including different content of activities, different approaches to completing activities, and different use of resources. Pupils are encouraged to be reflective about their own understanding, and are given opportunities to choose the level of activity they complete, through the use of chilli challenges.


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Perkin Elmer delivers a comprehensive portfolio of reagents and detection technologies, imaging systems, sample preparation workstations, informatics applications, and contract research services to support everything from drug, therapy, and disease research to the development and analysis of exciting new drugs and treatments. In addition, Perkin Elmer's translational imaging solutions enable scientists to image everything from a cell to a well to a tissue or whole animal.
Multimode Detection
Key Features:
- Best for research labs with multi-users, and relatively low-throughput assays
- Compact, lightweight and versatile for multi-user labs
- High performance for biochemical and cell-based assays
- All major detection modes: Abs, Lum, FI, FP and TRF
- Intuitive browser-based software for convenient remote control operation
- Internal dynamic filter wheel system, with space for up to 32 filters, provides ready access to filters for a large number of dyes
- For absorbance, choice of filter-based detection for best sensitivity or spectrometer for wavelength flexibility
Key Features:
- For research and assay development labs performing cell-based assays, at medium throughput
- Well-imaging, label-free technology, Alpha technology and conventional multimode detection technologies all on a single benchtop system
- Easily configurable and field upgradable
- Base unit with filter-based absorbance technology and temperature control unit (up to 65°C)
- Eight barcode identified filter positions
- Integrated barcode reading from all four sides of a microplate
- Kaleido™ Data Acquisition and Analysis Software
Genomic Analysis
Nucleic Acid Isolation
- Chemagic Prepito Instrument– based on PerkinElmer's proven technology for magnetic bead based DNA/RNA isolation and represents a top quality sample preparation system available as a compact benchtop instrument
- Chemagic Prime Instrument– Fully automated solution offering hands-free sample transfer, DNA and RNA isolation, normalization (optional), and PCR setup for research applications. This validated, single supplier solution offers high quality DNA and RNA which can be extracted from a variety of matrices
- Chemagic 360 Instrument– Nucleic Acid Extractor for Medium to High Throughput, represents the ideal solution for nucleic acid isolation in a huge variety of research market segments.
Nucleic Acid Analysis & Protein Characterization
Key Features:
- Accurate analysis of protein samples to accelerate Quality of Design Experiments
- Quantitate molecular weight, concentration and purity
- Optimal for high throughput needs with 96 and 384 well compatibility
- Intuitive touch screen interface with comprehensive analysis using LabChip GXII Touch software
- Data visualization with TIBCO® SpotFire® software
Key Features:
- Accurate analysis of protein samples to accelerate Quality of Design Experiments
- Quantitate molecular weight, concentration and purity
- Optimal for medium to low throughput needs–ideal for 12 to 48 samples per day sampled directly from 96 or 384 well plate
- Intuitive touch screen interface with comprehensive analysis using LabChip GXII Touch software
- Data visualization with TIBCO® SpotFire® software
Automated Liquid Handling Workstations
From benchtop application-specific workstations to complex customized integrated solutions our liquid handling portfolio automates your science.
- JANUS Liquid Handler Workstation– JANUS G3 portfolio invludes both dedicated, application-specific workstations and personalized automated solutions. It can be configured based on the size of the instrument, pipetting armtechnology, labware movement options, and a number of other accessories to fully automate your application.
- Sciclone G3 Liquid Handling Workstations– Can be configured to automate applications including genomics, proteomics, immunoassays, and cell-based assays. It offers high-throughput microplate sample preparation
- Zephyr G3 Liquid Handler Workstations– Zephyr G3 Workstation's small footprint makes it ideal for workbench operation. It provides ready access from all four sides to consumables and accessories. The Zephyr G3 workstation offer flexibility such as: partial tips loading, row wise and column wise serial dilutions, ability to hold lids while dispensing, seamless integration capabilities and barcode identification.
Imaging System
Quantitative Pathology
- NEW Vectra® Polaris™ integrates multispectral analysis, brightfield and fluorescence whole slide scanning, and automated slide loading for higher throughput
- Vectra® 3.0 provides multispectral and automated multi-slide imaging of up to 6 slides
- Mantra™ is a compact workstation ideal for getting started with multispectral imaging and for assay development, allowing you to free up higher throughput systems
High Content Screening
- Operetta CLS High-Content Analysis System– Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details.
- Opera Phenix High-Content Screening System– designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
In vivo Imaging
It's simple- for today's researchers there's an increasing need for in vivo imaging that enables you to visualize multiple events simultaneously and to extract the maximum amount of information. Whatever disease area you're researching, we have an in vivo imaging solution designed to meet your needs. Our portfolio includes optical imaging, PET imaging, and microCT, used globally by researchers in a variety of preclinical Imaging applications.
Our in vivo imaging solutions include
- 2D & 3D bio-luminescence imaging and fluorescence imaging
- PET imaging with integrated microCT
- High-resolution, high-speed, low-dose, microCT imaging
- Bioluminescence and fluorescent imaging reagents and radioimaging nuclides
Compare IVIS Imaging System HERE


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In 1968 the Rolling Stones debuted a song about Satan, Sympathy for the Devil. While I do not endorse the song in any way, and the title is simply ridiculous (the devil deserves no sympathy) the song does convey the evil one's deceptive and destructive motives and raises two very important questions: Do we know the evil one's name? And do we understand his game?
Pleased to meet you, Hope you guess my name.
But what's puzzling you, Is the nature of my game.
"The Nature of His Game"
Yes, Satan does attack us. He schemes to do harm and to cause us to sin. However, we know from the life of Job, and we must always remember, that Satan is restrained by God. Satan can't do anything without God knowing about it and even controlling it (either by stopping it or allowing it). God providentially protects His children from the evil one. While God also permissively allows trials, tribulations, pain, and suffering to enter our lives and to afflict us, it is always with a good reason and for a purpose that will be for our good and His glory. Often, when we find ourselves in the midst of a storm, it's difficult to believe that it's for our good, however, in such times, we must always return to that which we know:
- Our God is loving, faithful, and all powerful.
- Nothing happens to us that is not first "filtered" through His strong hands, His loving will, His faithful mercy, His amazing grace, and His all-powerful control.
- In all things, He gives us His faithful mercy, His amazing grace, and His mighty strength to endure.
With assurance, of God's presence, provision, and protection in all things, let's address the schemes of the devil. His goal is to diminish our witness and steal our joy. And always, he is determined to accomplish his will. The list is unending because the evil one is ruthless, so let's look at three "big" schemes and how they can be summed up in one subtle, but destructive, tactic.
The Big Three Schemes of Satan
- LIES: Satan schemes by using lies. He is the father of lies (John 8:44) and he attempts to deceive us by twisting or completely changing God's Word with the purpose of confusion leading to sin.
- TEMPTATION: Satan schemes by using temptation. He works to set before us sinful things that will tempt us to sin. While Satan cannot inhabit us and make us sin, he can certainly mess with us and tempt us to sin.
- MANIPULATION: Satan schemes by using manipulation. While Satan is not all-powerful, he is very clever and skillful at manipulating situations and people—always to achieve his purpose of provoking us to sin.
All of Satan's attacks are done with covert tactics. He is subtle and skillful in his ways. He uses deception to confuse and blind us, hoping we will fail to see the harm that lies before us and be unable to hear and heed God's Spirit's direction in our lives.
Satan's desire is to provoke us to walk in the flesh and not live in the Spirit. He schemes to turn us from Jesus to false gods, from God's ways to the ways of the world, from God's will to our own selfish desires, from hope to despair, from belief to doubt, from faith to fear, from peace to anger, from satisfaction to neediness…and the list goes on and on. Satan's hope is to shake our faith and do us harm.
Satan's Schemes in One Word
All three of Satan's schemes, lies, temptations, and manipulations—can be summed up in one word—DISTRACTION. From the Garden to our present day, Satan's way has been to turn our heads, to redirect our eyes, and to divert our attention away from God and put it on anything else. He wants to distract us and cause us to focus on worldly and fleshly desires. In the Garden, and with every one of us, he attacks using the lust of the eyes, the lust of the flesh, and the pride of life (Read Are there only three sins? What are they?).
C.S. Lewis illustrated this clearly in his book The Screwtape Letters, which tells of a senior demon, Screwtape, who instructs his apprentice nephew, Wormwood, on ways he can make Christians forget their beliefs, distance themselves from God, and ultimately sin. All of this, he taught, can be accomplished with distraction:
"What we want, if men become Christians at all, is to keep them in the state of mind I call 'Christianity And'. You know—Christianity and the Crisis, Christianity and the New Psychology, Christianity and the New Order, Christianity and Faith Healing, Christianity and Psychical Research, Christianity and Vegetarianism, Christianity and Spelling Reform."¹
Beware of the Distractions of Satan
When Satan distracts us with "Christianity and", we become prey for his schemes: his lies, temptations, and manipulations. But always remember, his three weapons cannot stand against the power that we have. "For greater is He that is in you, than he that is in the world" (1 John 4:4).
Just as Satan has the Big Three to cause us to sin, our God tells us the Big Three to avoid sin and live righteously. These three are the foundation of Christian faith:
- Love the Lord your God with all your heart,
- Love the Lord your God with all your soul, and
- Love the Lord your God with all your mind.
The foundation of everything is love (heart) which is the "fuel" of the soul (emotions and desire), and the "food" for our mind (knowledge and wisdom). Reasons for Hope* Jesus is a ministry of apologetics (the mind, knowing) and discipleship (the soul, living) and is dedicated to the glory of God (the heart, loving). Our homepage proclaims our mission statement of knowing, living, and loving with:
- Knowing: RENEW YOUR MIND IN THE WORD: Be transformed by the renewing of your mind. (Ro 12:2)
- Living: ANCHOR YOUR SOUL IN HOPE: This hope we have as an anchor of the soul, both sure and steadfast. (Heb 6:19)
- Loving: ESTABLISH YOUR HEART IN GRACE: It is good that the heart be established by grace. (Heb 13:9)
Don't Be Distracted
The Apostle James summed this up well, when he said "…every man is tempted, when he is drawn away [distracted] of his own lust, and enticed." (James 1:14)
Do not let Satan and his minions distract you. Stay focused on Jesus. The Apostle Matthew wrote that "the light of the body is the eye: if therefore your eye is single, your whole body shall be full of light" and Proverbs confirms, "the light of the eyes rejoices the heart" (Prov 15:30). Therefore, keep "looking unto Jesus, the Author and Finisher of our faith…" (Heb 12:2).
About Focusing Your Eyes on Jesus
Eph 1:18 [May] the eyes of your understanding being enlightened; that you may know what is the hope of His calling, what are the riches of the glory of His inheritance in the saints,
- Turn Your Eyes Upon Jesus
- Are you glad to see Jesus?
- Close Your Eyes and SEE Jesus!
- Pause to See Jesus
- Day by Day: Three Things to Pray
- See Jesus on every page of the Bible!
- We Wish To See Jesus
Read/watch more about Satan and his tactics:
- Why Did Satan Rebel Against God?
- Where did the sin of Lucifer come from?
- How Does Satan Attach Christians? What are His Big Three Schemes?
- How Much Should I Fear Satan?
- Is Satan's Real Name Lucifer? Or Should We Call Him Satan?
- Does Satan have a stronger influence on Halloween?
- Was Jesus a sacrifice to Satan?
- The "I Will" Statements of God and Satan and the "I Am" Statements of Jesus
- What Though The Vile Accuser Roar (song video)
The Top Ten Power of Hope Articles from 2018
- JESUS WEPT. Why? And…it's not the shortest verse in the Bible!
- The GATE OF THE YEAR: A Message to a Troubled Nation
- TWO WOMEN—Two Stories—Two Songs
- "LAUGHTER is the Best Medicine" Who Said That?
- The WIZARD OF OZ and God
- Following the Good, Great, and Chief SHEPHERD
- The best EULOGY to remember a father!
- ISRAEL Celebrates 70 YEARS As A Nation & the Significance for Christians
- HELLO DARKNESS, My Old Friend: The Sounds of Silence
Our Ministry's Two Favorite Articles from 2018:
Facing Terminal Cancer with Hope & Joy
When the Battle is Lost but the Victory is Won — Saying Goodbye to a Friend
The Top Ten Got Questions? Articles from 2018
- The Meaning of NUMBERS in the Bible?
- The Meaning of COLORS in the Bible?
- Is my TATTOO a sin?
- What do the 12 stones UNDER the JORDAN River mean? (Joshua 4)
- What Does It Mean to TASTE & SEE That God Is Good? (Psalm 34)
- Where did OT Saints go at death?ABRAHAM'S BOSOM? Where was that?
- Why Does the LGBT Use God's Rainbow For Its Flag?
- Should we call HIS NAME Jesus? Or Yahweh?Or Yeshua?
- Jesus said, I NEVER KNEW YOU. Why?
- Can JEWS go to HEAVEN without knowing Jesus?
Other Popular Questions:
- Something ALL Christians must know: IVDARR
- Is Satan's Real Name LUCIFER? Or Should We Call Him Satan?
- If BAPTIZED as an Infant, Do I Need to Be Baptized Again?
- Was Jesus CRUCIFIED on Wednesday, Thursday, or Friday?
- Why Is PRAYER Important?
- Is There a Hidden Message in Revelation 7?
- What is the Significance of the Wise Men's THREE GIFTS?
- Is It a Sin to Drink ALCOHOL?
- What Did Jesus Say About HEAVEN (and HELL)?
- Is SUICIDE an Unforgivable Sin?
Top Three Videos from Reasons for Hope* Jesus
- Christian Version of Leonard Cohen's Hallelujah
- Memorial Day Bagpipes Tribute: Amazing Grace
- Psalm 34 – Taste and See That the Lord is Good
Reasons for Hope* Jesus is a non-profit, donor-supported ministry.
A donation of any amount is helpful and greatly appreciated.
You Can Make a Difference: ~ CLICK TO DONATE ~
Use PayPal or a Credit Card for safe, secure giving.
Visit our Store
¹ Lewis, C.S. The Screwtape Letters, New York: Collier Books, 1982, pp. 115–116.


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Hello Kitty is having an identity crisis.
The pink-adorned Japanese import has been a favorite of cat lovers for more than 40 years, but one Hello Kitty scholar (yes, that is a real thing) has revealed that the character is not really a cat at all.
Christine R. Yano has studied the Hello Kitty phenomenon for years and was even tapped by the Japanese American National Museum in Los Angeles to help curate a Hello Kitty retrospective. After Yano had gone through her collection, she sent notes to Hello Kitty creator Sanrio for approval and learned a startling detail, the Los Angeles Times reported.
Hello Kitty was never a cat.
"I was corrected – very firmly," Yano said. "That's one correction Sanrio made for my script for the show. Hello Kitty is not a cat. She's a cartoon character. She is a little girl. She is a friend. But she is not a cat. She's never depicted on all fours. She walks and sits like a two-legged creature. She does have a pet cat of her own, however, and it's called Charmmy Kitty."
Yano then found even more details about the Hello Kitty character. She has a full name — Kitty White — and actually hails from the U.K.
"She has a twin sister," Yano shared. "She's a perpetual third-grader. She lives outside of London. I could go on. A lot of people don't know the story and a lot don't care. But it's interesting because Hello Kitty emerged in the 1970s, when the Japanese and Japanese women were into Britain."
Not everyone is on board with the idea that Hello Kitty is an adolescent British girl and not a cat.
poor hello kitty has been going thru her life for 40yrs convinced she was a Japanese cat but no she's an English HUMAN
— postillionage (@ALEXTVRNR) August 28, 2014
Wait I just read that Hello Kitty is actually a little girl, not a cat. You can go right to hell if you think I'm believing that @hellokitty
— John Feitelberg (@JFeitelberg) August 28, 2014
There was no explanation of how the human Hello Kitty somehow ended up with cat ears and whiskers, however.


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These kind of businesses are: (1) Sole Proprietorship, (2) Company, and (3) Limited Legal responsibility Firm. That is very true if the Kaizen course of adjustments add paperwork, knowledge recording and extra operational steps whereas administration is expecting the identical cycle time from employees.
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News >> Oncopsychologist's role in oncological clinics
A lecture was held at University after Ilya Chavchavadze, Georgia, Tbilisy on October 11, 2013. The topic was «Oncopsychologist's role in oncological clinics», where as a speaker took part The Master's program second year student of «Urartu» University Karine Sahakyan. The lecture consisted of theoretical and practical parts. In practical part art-therapeutic techniques applied both during preoperative and postoperative periods were presented.


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Research theme
Our research activities encompass the development and optimization of new therapeutic nucleic acids. Overall, their formulations, delivery, targeting according to routes of administration constitute our main research activity and challenge. This is a multidisciplinary research field requiring chemistry, molecular and cell biology as well as animal models.
Our long-lasting expertise in plasmid DNA transfer by synthetic vectors is exploited to the delivery of other types of nucleic acids including oligonucleotides, DNA decoy, siRNA, microRNA and mRNA. Our formulation called Lipopolyplexes, a ternary complex between Liposomes, a Polymer and a Nucleic acid is used in the frame of pre-clinical experiments for therapeutic applications.
This is the case of mRNA-based vaccines against cancer. We wish to strengthen this axis by improving in vivo delivery for pre-clinical trials and hopefully clinical trials. The access to large quantities of therapeutic mRNA thanks to the RNA cell factories project will open new potent mRNA-based applications such as gene editing using CRISPR/Cas9 mRNA for gene therapy. For this purpose, more potent mRNA delivery vehicles are designed.
Regarding gene transfer, we have now identified several devices for designing a DNA Integrative Artificial virus that could be an alternative of recombinant virus. This is tackled by optimization of each known devices, their packaging as well as the co-assembly of DNA and mRNA for gene integration by transposon/transposase or gene editing. For this, bioengineering of plasmid DNA is developed by coupling specific intracellular signals as peptide mediated cytosolic transport and DNA sequence for nuclear import.
We also explore the co-delivery approach of siRNAs, anti-miRNAs and/or DNA decoys against oncogenic genes. DNA decoys are based on bioengineered small nucleic acids for cell and intracellular targeting.
Sonoporation based on ultrasound (US) and microbubbles (MB) provides significant results to deliver nucleic acids and drugs in vitro and in vivo on tendon repair and tumor regression. Current developments of cationic MB with smaller size and high capacity of encapsulation as well as applications are going-on.
US waves delivering physical forces on cells can lead to cell death, drug delivery or tissue regeneration depending on parameters and cell types. Thus potential mechanical sensors involved in mechanotransduction, Early Growth response-1, Adenosine monophosphate kinase and Yes-associated Protein /Transcriptional coactivator with PDZ motifs is currently under investigation. Since those molecules are involved in pathways related to either proliferation or apoptosis, getting a clear knowledge of activated process will allow to fine tune the use of US.
RNA Therapeutics
These last years, we are witnessing the emergence of RNA based biopharmaceuticals as a new class of treatment and prophylactic for chronic and rare diseases, including cancer. RNA based-therapeutics are more promising than DNA therapeutics. It is now admitted that for RNA therapeutics clinical translation, a special care must be taken to improve their production, stability and cellular delivery.
In the project "Biomédicaments" we intend to set up a new technology to produce large amounts of vaccine-grade mRNAs in yeast. We search to improve the biological activity of mRNA based-therapeutics by studying the intracellular fate of exogenous RNA.
Skills / expertise
- Synthèse et chimie fine de l'ADN
- Vectorisation d'acides nucléiques
- Endocytose et trafic intracellulaire
- Microscopie confocale
- Cytométrie en flux
- Transfection
- Expérimentation animale
- Imagerie fonctionnelle in vivo
Our partners:
Significant publications:
Thibault T., Degrouard J., Baril P., Pichon C., Midoux P. and Malinge J.-M. (2016) Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-ĸB inhibition activity. Nucleic Acids Research - accepted 21 octobre 2016 - doi : 10.1093/nar/gkw1034
Pigeon L., Gonçalves C., Pichon C., Midoux P. (2016) Evidence for plasmid DNA exchange after polyplex mixing. Soft Matter 12 (33) 7012-7019.
Delalande A., Gosselin M.-P., Suwalski A., Guilmain W., Leduc C., Berchel M., Jaffrès P. A., Baril P., Midoux P., Pichon C. (2015) Enhanced Achilles tendon healing by fibromodulin gene transfer. Nanomedicine 11 (7) 1735-1744.
Midoux P. and Pichon C. (2015) Lipid-based mRNA vaccine delivery systems. Expert Review of Vaccines 14, 221-234
Pigeon L., Gonçalves C., Gosset D., Pichon C. and Midoux P. (2013) An E3-14.7K peptide that promotes microtubules-mediated transport of plasmid DNA increases polyplexes transfection efficiency. Small 9, 3845-3851.
Billiet L., Gomez J.-P., Berchel M., Jaffrès P. A., Le Gall T., Montier T., Bertrand E., Cheradame H., Guégan P., Mével M., Pitard B., Benvegnu T., Lehn P., Pichon C. and Midoux P. (2012) Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line. Biomaterials 33, 2980-2990.


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Blog Archives
Inside The Game – General Game Structure
This article is third part of the series called as Inside The Game. For those, who are not familiar with Inside The Game series, this series will provide the articles and tutorials related to mechanisms and architectures of the game. Also, in this series, you will learn to think like a game developer. Now, if you have not read the last part of this series, please click here to read it. I am summarizing the last part here for those who have not read. In the last part, it was discussed about animations, simulations, and games. In simple words, game is a controlled animation, which takes the input from user unlike animation and simulate the world like interaction. This part is more technical than last two parts but it is also sort of general as compared to the implementation or programming in any computer language. But, this article will be very important to know when it comes to game development.
Okay!!! Let's start our article today. Today, we will discuss about the general structure of any game. You might know that there are many different types of the games such as platform games, First Person Shooter (FPS) or Third Person Shooter (TPS) games, strategy games, board games, and so on. So, it is very important to know about the structure of these games. The structure keyword means how the game is designed and what components together make a game. I am not explaining here about any specific type like how platform games are developed, Today, I am explaining about how any type of game is structured. Software include lot of coding, and sort of graphics as well for User Interface. But, normally, all software contain same Operating System's User Interface Components like Buttons, Combo Boxes, Radio Buttons etc. So, it doesn't become a problem to focus on User Interface more than the functionality of the software. However, in games, story takes turn to other side. Games includes many disciplines and field other than just coding. Following figure shows some of the disciplines involved in any game. It is not necessary that all the disciplines can be used in the game, but it is also possible that some of the disciplines are used in the game.
As in the figure, it is clearly shown that game contains very different disciplines to work on at the same time. For example, let's take graphics here. Graphics is a very important part in any game, because it is the first impression of the game. The most first thing user observes in any game is the graphics. So, the more good are graphics, the more users are likely to play the game. But, let's say that your game has got amazing graphics, but the game is slow and not good in interaction and gameplay, then users will not play the game. Because, they already observed the graphics, and they liked it so they gave a chance to your game, but when they played it, they didn't find it enjoyable and interactive, so they just left your game. Interestingly, you can see Game Effects & Gameplay in above figure as part of the game. These all parts play almost equal role in making of any game. Let's take Artificial Intelligence shortly AI here. You can say AI like it is the brain of the game. How computer will react and respond to the user input is the AI of the game. The enemies in the game, called as game bots or game agents, use AI to make decision. We will come to AI in details soon. Another important part of the game is Game Logic & Game Flow. Now, this is completely coding work, and in this part, all other disciplines like graphics, resources like images, sounds from Game Music part, databases, networking, etc. are assembled. You can say it the most important part of any game, but this part becomes zero, if no other part is available to you. So, all the components are tightly dependent on each other.
Well! I hope that you have known about different disciplines of the game, so let's talk about the structure now. Behind each game, there is an engine running called as Game Engine. In the business world of games, game engine is like gold mine. You can make many games with game engine. Game engine's objective is to manage all the data involved in any game. Following figure shows the role of the game engine.
As you are seeing the figure, game engine is managing and controlling other sub-engines like Graphics engine, AI engine, Physics engine, Sound engine, and so on. Game Engine manages all the game data and makes any game come to life. The way of game engine is to keep connected all the engines through one medium, and that medium is game engine itself. It basically takes game data, sends it to the AI for decision making, then sends it to Sound for playing, then sends it to Physics for real-life interaction, and finally sends it to the Graphics for rendering and displaying on the screen. This process keep to be repeated as long as the game is running. This is how a game engine gives birth to a game. On completing this article, I would like to ask you a simple question here:
Thanks for reading this article and series. I hope you liked it. Any suggestions, comments, or feedback is open. Thanks…. In the next part, I will discuss about some basic concepts used in game development like Graphics Engine, Game Engine, and so on. To read the next part, Inside The Game – Graphics Engine, Game Engine, and The Game, please click here.
Related articles
- Inside The Game – Animation, Simulation, and Game (gamyguru.wordpress.com)
- The Game Engine Dating Guide: How to Pick up an Engine for Single Developers (learn-cocos2d.com)
- Unity 4 game engine allows publishing to Linux platforms (linuxuser.co.uk)


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Campus Collaborative is our overarching network of campus bookstores, campus fitness centers, our new college fundraising platform, Campus Causes and more which allows us to connect your brand directly to the college market at the right place and right time. Interested in learning more about Campus Collaborative? Click here.
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Jo Broadbent
GOOD LUCK to all the students in theior future careers, whether scientific or not. And thanks for all the great questions! it's been really good fun.
Curriculum Vitae
EducationHulme Grammar School, Oldham 1983-1990
QualificationsEdinburgh (BSc Molecular Biology) 1990-1994 / King's College London (PhD Developmental Biology) 1995-1999 / London School of Hygiene & Tropical Medicine (MSc Public Health) 2004-2005
Work HistoryRestaurant / Newsagent / Centre for Genome Research / Human Fertilisation & Embryology Authority / Various NHS – Primary Care Trusts, Hospital, Strategic Health Authority / University of East Anglia
Current JobConsultant in Public Health
NHS North East Essex
Favourite thing to do in my job: the van der graaf generator that makes your hair stand up in physics lessons
My Work: I make sure the health services in my area are as good quality as they can be. I also make sure they treat all the illnesses that people in my area have.
Read more
I use research about the illnesses people have in my area to make sure that the health services we have are the right ones. Its no use our hospital being able to do 500 hip replacements if we only need 50. But not treating any broken legs!
We only have a fixed amount of money to spend on all the NHS services in my area, so sometimes we have to decide which services to spend money on, and which ones not to spend money on. Do we need more midwives to deliver babies, more x-ray machines, or more help for people to stop smoking? Or more IVF treatment?? Which is more important?
To do make decisions about which health services to spend money on, we look at science research about how well the different services work.
We also think about how serious an illness is (is it a heart attack, or a stubbed toe?)
We ask people what services they want (do you want to see doctor once a week, or look after yourself if you can?)
We also think about how much money different services cost (if one heart medicine costs £2 a day, and one costs £20 a day, but both work just as well, which one should doctors choose to give patients?)
One other thing to think about – I work in part of Essex that includes Colchester, Clacton-on-Sea and Harwich. A baby born into a family living near Clacton is likely to die 13 years before than a baby born 20 miles down the road. 13 years less life!! Is that FAIR? An important part of my job is trying to make that 13 year life difference smaller. The NHS helps people all live longer and healthier lives. But it also tries to make how healthy people are more equal.
My Typical Day: Busy. Talk to a lot of people. Send a lot of email!
Read more
I do lots of calculations using information from science research. I go to lots of meetings where we talk about how to make health services better. I talk to doctors and nurses and health managers, but also local people, and people who work for local councils and charities. I get a LOT of emails. LOTS.
What I'd do with the prize money: Raise awareness of how to know when someone has had a stroke – the sooner someone phones 999 and they get to hospital, the less likely they are to die or suffer a major disability
Read more
I would put the money towards a campaign to increase people's awareness of the symptoms of stroke.
A stroke is a 'brain attack'. A stroke is what happens when the blood supply to part of the brain is cut off. Blood carries essential nutrients and oxygen to the brain. Without a blood supply, brain cells can be damaged or destroyed and won't be able to do their job. This can affect lots of different parts of the body. If the part of the brain that controls how you move your legs is damaged, you might not be able to walk. If it damages the part that controls speech, you might not be able to talk.
The faster someone gets to hospital after a stroke, the sooner they get treated and the less the damage to the brain will be. So its really important that people know how to recognise when someone's had a stroke so they can call 999 straight away.
There is a really simple campaign called ACT FAST – FAST stands for how recognise when someone has had a stroke –
F – Facial weakness – can the person smile? Has their mouth or eye drooped?
A – Arm weakness – can the person raise both arms?
S – Speech problems – can the person speak clearly and understand what you say?
T – Time to call 999.
Here's weblink to the campaign –
My Interview
How would you describe yourself in 3 words?
small, excitable, a mum
Were you ever in trouble at school?
No, too much of a geek!
Who is your favourite singer or band?
Stone Roses, Kings of Leon, Pixies….. Am I allowed more than one?
What is the most fun thing you've done?
jumped out of a plane
Tell us a joke.
What do you call a fairy that needs a bath? Stinkerbell.
My profile link:


text: How do you get 'open world' right? Feb 11, 2019 13:09:46 GMT cloud9 and XCPTNL like this Quote Select PostDeselect PostLink to PostMemberGive GiftBack to Top Post by link2twenty on Feb 11, 2019 13:09:46 GMT What does BioWare need to do to get open world's right? Recently I watched noclip's documentary about HZD and some of the points I took away wereThey made the map smaller, and denser, over timeStory impacted everything first and foremostNon-story quests were given a lot of time to make them feel connectedFetch quests were sprinkled in near the end as they didn't want many.I think, looking at ME:A and DA:I, BioWare have had a bigger is better mentality and I'm not sure that's what open worlds should be about.Do you have any thoughts?


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How to get rid of this?.
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Therefore, it is necessary to take the proper steps to protect your homes from termites and get rid of them. Our team will prevent this by taking some effective treatments with least impact on the environment.


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This tiny fey resembles a 1-foot tall elf with small bee-like wings, silver hair, milk white skin, and icy blue eyes. It is dressed in colorful garments of blue, silver, or green and carries a tiny short sword in a scabbard slung across its backs, resting between its wings.
Mimi CR 1
N(G) Tiny fey (cold)
Init +4; Senses low-light vision; Perception +5
AC 19, touch 17, flat-footed 14 (+4 Dex, +1 dodge, +2 natural, +2 size)
hp 4 (1d6+1)
Fort +2, Ref +6, Will +3
DR 5/cold iron; Immune cold, SR 15
Weaknesses vulnerability to fire
Speed 20 ft., fly 50 ft. (average)
Melee short sword +6 (1d3-3),
Space 2 1/2 ft.; Reach 0 ft.
Special Attacks group casting, lower temperature
Spell-like Abilities (CL 8th):
At will—invisibility
2/day—frost fingers (as burning hands, but cold damage, DC 13)
1/day—cone of cold (DC 17)
Str 4, Dex 19, Con 14, Int 15, Wis 13, Cha 14
Base Atk +0 CMB +2; CMD 10
Feats DodgeB, Weapon Finesse
Skills Bluff +6, Craft (any one) +6, Escape Artist +8, Perception +5, Perform (limericks) +6, Perform (sing) +6, Sense Motive +5, Stealth +16, Survival +2, Racial Modifiers +4 Perception
Languages Common, Elven, Sylvan
Group Casting (Sp)
A group of three or more mimis together can use freezing sphere (DC 18 half), once per day. Caster level 12th. The save DCs are Charisma-based.
Lower Temperature (Su)
A mimi can, as a free action, lower the temperature in a 10- foot radius around its body by 20-80 degrees. Creatures in the area that are not immune or resistant to cold may take damage.
Environment cold forest and plains
Organization gang (2-4), band (6-11), or tribe (20-80)
Treasure no coins; 50% goods; 50% items
Mimis are 1-foot tall mischievous creatures that inhabit cold forests and fields and derive pleasure from playing tricks on creatures that wander into their icy realm. Mimi tricks are always harmless and include such things as throwing snowballs at a creature, creating a patch of ice on the ground and watching a creature slip and fall, or turning invisible and sneaking into a sleeping creature's camp wherein they put snow or ice in the creature's boots, clothes, or backpack.
While frolicsome, mimis are generally good-natured and friendly towards those they encounter. They often lend aid to creatures in need, especially those that have helped a mimi in the past. Mimis will not lend aid or assistance to creatures of a malign nature and tend to avoid such creatures if possible. They are on good terms with most other fey creatures, though they find brownies to be a little too "stiff" for their liking and buckawns to be a bit too gruff.
Druids and rangers can detect the presence of a mimi or group of mimis with a successful DC Survival check.
Mimis are non-aggressive creatures and rarely attack, unless potential adversaries are inherently evil. They prefer to avoid combat if at all possible but if drawn in, they open using their frost fingers. Against more powerful opponents, mimis begin combat by blasting their foes with a cone of cold.
A persistent foe that wishes to continue the battle against a mimi (after being hit with its frost fingers or cone of cold) is subjected to a rapid decrease in the surrounding temperature. A mimi lowers the temperature just enough to possibly damage an adversary and maybe force it away; its goal is not to kill it.
Mimis usually turn invisible and flee if they cannot drive their opponents away.
Mimi from the Tome of Horrors Complete, Copyright 2011, Necromancer Games, Inc., published and distributed by Frog God Games; Author Scott Greene.


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Listen To BBC Radio's In-Depth Primer On Russian Experimental Music
Nick Luscombe talks to Moscow musician Ivan Zoloto about the artists who shaped the region's underground scene.
BBC Radio 3's latest installment on Russian music proves that there's a far-reaching appetite for the region's underground and experimental sounds. In this 25-minute interview, Nick Luscombe talks to the Moscow-based DIY artist and New New World Radio boss Ivan Zoloto about the bands that helped to define the region's experimental sound, like the rock band Kino (pictured above) and the Novosibirsk composer Eduard Artemyev.
Zoloto goes on to discuss his current projects which aim to showcase some of Russia's brightest musicians and music curators as well as to share some song suggestions from his personal collection. Listen to the full BBC Radio 3 piece below. Then, read a more extensive interview with the Russian artist and his musical roots on Calvert Journal here.
Read more: 9 synth artists who defined Eastern Europe's post-Soviet sound


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The Liberal Democrats today proposed the building of a £12 billion new high speed rail link from London to Newcastle and Edinburgh slashing the journey times between the two capitals and Tyneside.
Leader Charles Kennedy believes the new line is needed to benefit the economy and to free up existing routes for more local trains.
Under the plan, outlined by Liberal Democrats transport spokesman John Thurso, work would begin in 2013 and the line would be operational by 2017.
The new link would go from London through Birmingham, Leeds and Newcastle to Edinburgh.
The plan follows the £9 billion upgrade of the West Coast mainline from London to Glasgow and would be partially financed by not proceeding with plans to improve the existing East Coast main line between King's Cross, Newcastle and Edinburgh.
With trains operating at 225 kilometres per hour, (more than 140 mph), the journey times from London to Edinburgh would be less than three hours which should persuade many passengers away from flying thus reducing the pressure for new runways.
The route could pay for itself in 15 years.
Mr Thurso said: "Every passenger knows that Britain's railways are fit to burst.
"The endemic short-term approach that successive governments have inflicted on British transport has become a serious barrier to economic growth.
"It is vital that we commit to this project before congestion brings Britain to a standstill."
The Liberal Democrat Conference in Bournemouth also backed calls for a major modernisation of the railways and support for the waterways as part of a 30-year strategy for transport.


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This is lovely!This is just...so great!I love it!+fave
Artist Comment
This is a vector I made for the contest at Vector
Wallers. Hopefully, I will win something!
It took quite some while to finish, mainly because I didn't have the patience to work on it until a few days ago. It looked horrible simple as it was back then, and I felt the urge to send it to the Recycle Bin at first. However, I needed a vector for the contest, and I found this suitable for the idea I had in mind. As soon as I upload the wallpaper I used the vector on, I'll post a link to it so you can see what I mean.
I hate those ribbon things. I don't know why they're there. Probably just to bug me. I didn't enjoy vectoring them, since I was almost done, and I noticed I had forgotten to work on those OX
Guess this vector was pretty much self torture. And to think that I actually wanted to add more stuff on her outfit for the wallpaper T_T...
Layers: 38
Scan: here. Thank you for submitting it! :D
Timeline: about 2 months
Title: no, it's not supposed to be "Swan Princess". Too clique.
Original size: 2200 x 5145 (why did I have to shrink it? why? T_T due to MT standards...)
PNG file: here
Wallpaper: here
IF YOU USE THIS VECTOR, PLEASE CREDIT ME! I'd love to see if you used it on anything, by the way :)
Dark Wallies | Vectory | Vector Wallers | User Page Skin Designs | Sola Fans
More Princess Tutu Indy Art
Browse Princess Tutu Gallery: Recent | Popular.
FutatsuNoNegai Jul 11, 2007
IzumiChan Jul 12, 2007
The link for "scan" leds us to a clover scan~ >u<''
Really well done~ :D
I just feel the outlines of her eye'ness should have a darker blue tone, it looks a bit phantasmagoric~ >u<''
I love Tutu too!~ XD XD
Zoekin Aug 01, 2008
Oh wow!
Looks terrific!
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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License
Snuffop Web Blitching comment guidelines Keep it civil aka don't be a jerk We're going to get into the thick of a lot of heated discussions and that's okay. These discussions often entail topics that we all personally care a lot about and will passionately defend. But in order for discussions to thrive here, we need to remember to criticize ideas, not people. So, remember to avoid:* name-calling ad homonym attacks Responding to a post's tone instead of its actual content.
Resume Marty's Man Page Resume Music Projects: (slappin da bass of course) Back In the Chicago Area 2017 Dragonlore NW Indiana Original Metal Official Website Screamking NW Indiana Original Metal Trainwreck Arena Rock Covers SoSub Chicago San Antonio Maiden Killers Tribute to the Di'anno years Zero the Hero San Antonio Original Metal Gun Slingers San Antonio Country/Americana Victory or Death San Antonio Original Metal NN Indiana 2011 Stone Magnum Michigan City Original Metal Links of Reference and Note Government Congressional Bills past and current Pay attention to what our Representatives are doing or NOT!
Heading to San Antonio for a Corp visit So I'm headed to San Antonio the last week of September to visit corp HQ for Rackspace and visit friends that I haven't see in a year, since moving back to Chicago Marty
Info Moving the Blog over to Jekyll for Blogging. I can keep up with Emacs (Spacemacs) to do most everything. ## Emacs (Spacemacs) I've been using vi/vim for years and I was introduced to Spacemacs, the bridge between Emacs and vim (evil) I've found the Emacs ecosystem to be very alive and busy. Where has this been all my time on computers? Well right in front of my face! I had missed this Huge advantageous system of editor, IDE, mail, news reader, PIM, etc.
Jammin! My cousin "=Robert"= was able to get a few Tickets for the Korn Slipknot show here in San Antonio on Sun. Nov 2, 2014 7:00 PM Looking forward to the show. Update November 3, 2014, I Went to the show last night, The bands seemed to do a great job. Where we were sitting the sound for Korn was good. The bass drum was a bit over bearing the bass.
Mom Mom had come down for the holidays and to visit, as well as soak up the good weather of winter in south Texas. We Just took her to the airport and she's not looking forward to the cold weather of the northwest Indiana Chicago Area. Work Work is good. Rackspace is a really good place to work.. they don't just say that. Forbes says it, and so do I. I have never worked for a place where I have no interest in keeping my options open.
Victory or Death a group of Bastages In San Antonio who are ready to Rock your ass off.. Has Released our First Recording Victory or Death. Facebook
New gig at Rackspace For those who haven't heard Rackspace offered me a position as a Linux engineer II. Located at their San Antonio Tx Location. They made a great offer and paid to relocate us to Texas. Pack and Ship, as well as ship one of the Vehicles. We made it down to Texas Tuesday the 17th, I would recommend Flying, 1200 Miles in an explorer with my Wife, Samara (tabby), Jazziril and Sydney (peanut) our Australian shepherds.


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The San Diego Mesa College softball team (25-10, 11-4 PCAC) is in a tight race for the PCAC title. With three games remaining in the regular season, and currently one game behind Palomar College, the Olympians must play perfect softball.
With strong pitching performances from Christiana Fejeran (4-2) and Karli Ramsey (8-4), the Olympians were able to shutout both College of the Desert and Grossmont College 9-0.
Kaleigh Lane continues her strong 2019 campaign leading the team in four categories. She currently leads in batting average (.471), RBI's (47), home runs (8), and stolen bases (13). During the win against College of the Desert, Lane turned in an amazing performance with a triple, a home run, stolen base, and 4 RBI's.
Current PCAC Softball Standings
Palomar College 12-1
SD Mesa College 11-3
Southwestern College 10-3
SD City College 9-5
College of the Desert 6-6
Imperial Valley College 4-9
Grossmont College 3-9
San Bernardino Valley College 1-10
Mt. San Jacinto College 1-11
Remaining Regular Season Games
Wednesday, April 17 @ Imperial Valley College 1:00 p.m.
Thursday, April 18 @. Rio Hondo College 2:30 p.m.
Tuesday, April 23 vs. Mt. San Jacinto College 3:00 p.m. @ Mesa College


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Amh Garanjy is a non-player character from Final Fantasy XIV. She appears during the Starlight Celebration seasonal event.
Profile Edit
Appearance Edit
Amh Garanjy is a keeper of the moon Miqo'te with pink hair and blue eyes, she is seen wearing the Starlight robe, though she has appeared in different starlight outfits over the years.
Personality Edit
Amh is a joyous person happy to host the festivities of the starlight festival and come up with new ideas to make everyone happy. She has a soft spot for children and will help them if they are unhappy during the festivities.
Story Edit
This article or section is a stub. You can help the Final Fantasy Wiki by expanding it.
Retrieved from "https://finalfantasy.fandom.com/wiki/Amh_Garanjy?oldid=3035807"
Community content is available under CC-BY-SA unless otherwise noted.


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10 in. Chicago Black Floating Shelf (Price Varies by Length)
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This floating wall shelf is perfect for any room of your home. Easy as hanging a picture this shelf shows no visible supports and actually appears to be floating. Just perfect for displaying pictures and family artifacts, this piece is sure to make a splash in your home.
35.4 in. L x 9.84 in. W Lighted White Floating Shelf
The lighted floating wall shelf adds ambience to room and accent special accessories artwork at the same time. An added dimming light feature helps you control reading light, illuminating the room with just the right touch. You can install this lighted shelf over your bed, in the kitchen under cabinets or over a work desk. Add creative storage to your home to reduce clutter and brighten up a room at the same time.
Curvo 8 in. x 40 in. Black Glass Shelf with 2 Pelican Brackets
The Vincenza Curvo 8 in. x 40 in. Black Glass Shelf with 2 Pelican Brackets offers a unique slightly bent rectangular shelf, resulting in a wave design and providing 2 levels. You can create an interesting wall decoration by pairing this shelf with other glass shelving. Kit contains 2 Pelican Brackets.
$24 to $102


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Today is the last day of June and I can't wait to end it very soon.
See, this month is a little catastrophe to me; Why?
I will be moving to a new room with five strangers around. The rent is cheaper to compare, but oddly, I feel like lost. Maybe because I used to live with persons I knew for years and this is really something new to me. I don't know until when it finds me comforting about the sight of strangers at home.
I'm in the state of "hibernate friendship". A friend was wrathful at me, believing that I bullied her for something which I don't consider of. Whatever comes in my mind, I express it bluntly, if someone sees it as hounding then what shall I do? Do I have to always say sorry? To shut up? To choose my words? To bite my tongue?
I am most grateful if someone can tell me right into my face that they don't like me anymore, or I have hurt them so I can apologize. It's irritating to be ignored and to take silence because this is not the way I graft my life for.
This is so exhausting when issues stands unresolved , more wearing when I have no strength to protect the relationship, when promises are made to be broken. I might end up making a wrong decision, but this is how I take my way.
I am anxious this time to whether be myself or someone else. To be myself, then they will hate me, or to pretend someone else, but feeling sorry for the not being real.
I maybe lost control over everything in my head now, but I know exactly who I am.
Take me as I am or watch me as I go.


text:
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MITZI GEORGETTEMonday, January 21, 2019 3:48:43 AM
If you were on the Internet in the "Best reaction gifs ebaumsworld sexual harassment" aughts, you probably already know exactly where the above sentence comes from. The nasally voiceover is unmistakable, as are the crude and colorful sketches. Mic recently spoke to Windsor, now 31, about the animation's origins, the consequences for his own career and the evolution of viral videos on the Internet.
Could talk a little bit about the process of the creation — how you got the idea for it, who you worked with, and how you put it into motion? It was circa or so, and I had just graduated high school, and some friends and I were hanging out late at night and talking about the state of the world.
We were at a park, and we started drawing pictures of missiles flying from one side to another with tanbark on the sidewalk. It was that period in time when really crappy flash videos were the thing.
I just basically laid down the voiceover myself. The process wasn't much more than just like, recording the voiceover and then sort of going through and making crude flash drawings. So after you created the video, how did you get it out there? Was it on albinoblacksheep.
Best reaction gifs ebaumsworld sexual harassment it was on that site and, I feel like, eBaum's World.
This was pre-YouTube, so places like that were starting to curate Flash videos and stuff. It doesn't even really have my name on it or anything. I sent it internally — I didn't actually post it anywhere. I sent it to some of the same friends — this was back in the days of, like, pirating and Napster — and one of my friends had all of his channels overseas for getting pirated music and stuff. He sent this to some of his people, his hacker people overseas, and somebody somewhere eventually posted it.
It made its way online somehow, but I'm Best reaction gifs ebaumsworld sexual harassment exactly sure how. What was the timeline from when it initially came onto the scene to when it totally blew up?
What was the response like? Did you gain any sort of notoriety from this video, from the audience?
And that was basically because of the animation. The creative director who was working on those Nike spots called me and was basically wanted to do the same type of thing. And this was when, like, a lot of marketers and ad agencies were like, "Oh, viral videos! We need to figure out what to do with viral videos!
Some people will occasionally quote it and be like, "Oh, I remember that video! The widespread-ness of it is kind of cool.
It's kind of weird how it became Internet-popular. I was heading in the direction of animation and filmmaking, live action, that sort of thing. And so to get connected, especially with Wieden, early on, was huge. But I felt like I had a little bit of a tug-of-war early on, because I was getting gigs that wanted that sort of style of animation, and I was like, no, I want to make something cool and flashy and design-y!
Were there any negative consequences in terms of your career and the path you ended up going down? As soon as my mom saw it, she was horrified at all the foul language.
But I think she's gotten over that. If you go on the YouTube comments, there's a good mix of people who love it and people who think it's the worst thing that's ever been created.
YouTube comments are a good place to humble you a little bit. I feel like the world got over the crudely animated Flash video. It had its heyday and then we naturally got "Best reaction gifs ebaumsworld sexual harassment" of it. Did that influence the content you put into the video? I think we were already in Iraq.
The invasion occurred from March to May Some things have changed since then, and some things haven't, but I think it was just that sort of Some of the actions we were taking as a country were questionable in our minds, and just seemed like we were doing what we've done a lot of in the past, which is to go somewhere and create more enemies for future generations. And I probably wouldn't have wanted any YouTube money, so I wouldn't have put my name on it.
But, you know, maybe I would have if I had known it would have gotten quite the traction that it did. But, no, it was just sort of like, oh, damn, there's 1, hits on this thing already, and I didn't realize it!
I don't know exactly. The dude who tracked me down from Wieden, he used Internet magic or something.
I had a personal portfolio website at the time that it somehow got linked to. There was also a website that someone put up, like, endoftheworld. The website that sits at that URL is slightly different now. But no, I'm not exactly sure. The Internet is a pretty amazing place. It certainly is for things like that. Do people still refer to you as the "End of the World" guy?
I work for a shop that does Web explainer videos, and there are a couple of other designers that work there that knew of [the video] when I started working there, "Best reaction gifs ebaumsworld sexual harassment" they would say, "I need to take a picture of you to send to my college friends because we used to watch this video.
I made a bunch of money — at least a bunch of money for a year-old, for an entry-level animator. I made the most money off the voiceover. I had to join the Voice Actors Guild and was getting residual checks. Total, between those two: From "The End of the World" itself, I got nothing. Yeah, that [profit] would have been from jobs after.
If I had known it would get several million hits on YouTube, and that I could have monetized that, then maybe I would have put my name on it. Do you think that there's a formula for a viral video? If there were to be a recipe for it, what would be involved? It would be two parts popular culture, two parts political climate, two parts nostalgia reference, and then — no, I don't know.
Something really "Best reaction gifs ebaumsworld sexual harassment," something really funny, that people want to share. That's been the question of advertisers since around — what makes a viral video? Viral content has become more commercialized, whereas back when your video came out, it was this new thing that people weren't as accustomed to. Without being too reductive, it was a bit more of Best reaction gifs ebaumsworld sexual harassment innocent time — it wasn't about making money, and it wasn't about selling things.
And even with the Nike spots that I did [after], they were trying to reference that same style. I feel like the response in general was basically that, uh, we can tell what's going on here — this is a Nike ad that's trying to look like this other thing. That sort of thing. What do you make of the timing of the video's release? Do you think it played a role in ushering in a new age for the things that are popular on the Internet?
I like to think that it helped the progression of funny Flash videos and animated Internet videos. As far as ushering in a new age, I don't know. I hope that it progressed that medium, anyway. But that's sort of how things are on the Internet — it's so exponential, a bunch of people see one thing, and then it just — it is so explosive. What happened after "The End of the World"? What are you working on now?


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White Sage Resin Incense
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The White Sage ( Salvia apiana) is an evergreen perennial shrub native to the southwestern United States and northwest Mexico. White Sage is widely used by Pacific Coast Native American groups, its leaves are smudge in many smoke-based purification rituals. A study performed at the University of Arizona in 1991 demonstrated that White Sage possesses antibacterial properties. Ingredients: Pulverized White Sage leaves, pulverized Breu Resin and Vegetable Charcoal. Place it on an incense holder or fire-resistant surface.