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Car Detailing Tips - Detail Your Car
Maintaining your paint job is easier than you think with these tips on how to detail your car.
'It's not that bad, really. Some people balk at the notion of spending half a day cleaning and detailing their cars. We're here to reassure you there is no black magic involved in detailing. You just need to be able to recognize which products to use for each surface and condition. Combine that with some manual labor and a few hours, and your car will be looking like new. Plus, the more often you do it, the easier it will be, and the longer your paint job will last.
Now, we are fully aware that photos of a bunch of dudes washing a car might cause more than a few of our readers to fast-forward through these next five pages. Our more impassioned readers might even send hate mail, so we thought we'd mix things up a bit. Feast your eyes on the beautiful Paige Peterson as she tackles detailing duties on Greg Nicholl's Nova. You can thank us later.
Wheel/Tire CleanerThey say you should wash the car from the top down, but we're not ones to always follow convention-we actually like to clean the tires first. It's been our experience that tire cleaners work best when applied to dry tires. It seems to break up old tire dressing better that way. So we clean both the tires and wheels first before a drop of water even touches the car.
Those "no touch" hose-off tire cleaners work OK, but the best products still require scrubbing, so spray liberally and use a scrub brush to get rid of all the road grime and brake dust. To clean the wheels, it's best to use one of the newer, all-metal wheel cleaners to avoid damaging the finish. They're formulated to work on bare aluminum, magnesium, or painted wheels. Soak the wheels with the cleaner and scrub lightly with a soft-bristle brush or an old terry-cloth towel. Rinse both the wheel and tire thoroughly. Do one wheel at a time to prevent the cleaners from drying before you rinse them off. If you have unpainted wheels, they can then be cleaned with mag and aluminum polish. Use a terry-cloth towel to wipe the polish on, and wipe the residue away with a clean towel. Be sure to use old towels, though-the polish turns black as it cleans the metal.
WashIt's not rocket science-the foundation for any detailing job begins with a thorough washing. For best results, wash your car in the shade, and use car-wash soap rather than dish soap or another type of cleaner. Mix in enough soap so that the water feels a little slippery between your fingers. Rinse the entire car first to remove larger particles of dirt, then use a thick wash mitt or high-nap terry-cloth sponge to apply the soapy water. These dense applicators will trap any dirt and particles and prevent them from scratching the paint surface. It's best to work a section at a time, rinsing after each to keep soap residue from drying on the paint. Once done, dry the car with a soft terry-cloth towel, a water blade, or our favorite, The Absorber synthetic chamois.
PolishPaint gets its gloss by reflecting light-the more it reflects, the glossier it looks. But the paint's surface must be as smooth as possible in order to reflect the greatest amount of light. Conversely, scratched and damaged paint looks dull because its rough surface does not cast back as much light. Think of suede or a primer job-it's not glossy because the surface is not smooth. The surface of your topcoat will wear out in time too. Freeway driving acts like a sandblaster, bombarding the paint with grit and particles. Combine that with excessive sunlight, hard water, bird droppings, and careless people brushing up against your car, and eventually your paint appears faded because of tiny scratches that have developed with time and use.
One option is the clay bar, which works by picking up small particles of dirt and minerals left behind in water spots. The paint needs to be wet so the clay will glide smoothly over it, so spray the area with quick detailer first. Rub the clay lightly across the paint until it feels smooth. Dry with a soft towel and move on to the next section.
Clay bars only remove contaminants embedded in the paint, however, so what do you do about scratches? Sometimes, a coat of wax will fill light scratches and revive the shine. Try a light coat on a small area to test. If it doesn't work, you'll need to break out the big guns.
Polish is a very general term referring to a range of products that remove or fill in scratches, usually by means of abrasives. Other names you'll see on parts stores' "wall of wax" are cleaners, cleaner wax, swirl remover, and glazing compound-clever terms, but they are all types of polish. Most brands market their polishes in steps from mild to heavy, so you'll probably have to buy all three and experiment-be sure to start with the mildest formula first, though. Polishes can be applied by hand using a foam applicator or by machine. Apply the polish and buff until the scratches fade; it should take less than a minute. Then wipe the residue off with a microfiber towel. If the scratches are still there, move up to the next higher formula. Keep moving up until the scratches are gone. Smooth out any areas where you used the rough stuff with a final coat of the mild formula prior to waxing, and your paint will look a mile deep.
WaxSomeone described wax to us awhile ago as a coating that keeps the paint from drying out. Paint, like most other materials in your car, will oxidize, fade, and break down over time. Wax is like a moisturizer for your paint. More than that, it provides a layer of protection against the sun's UV rays, dirt, and grime-all the crap you want to keep off your car. The best waxes are made from carnauba, an oily substance that comes from the leaves of a palm tree native to Brazil. Did you ever notice the way water beads up on some plant leaves as if they were waterproof? Some brilliant guy decided to put this stuff on his paint, and it worked.
Paste wax requires more effort to apply, but the finish lasts longer than liquid wax. However, we prefer the liquid stuff. It goes on quickly, and we don't mind waxing our car more than twice a year. Apply wax with a soft sponge applicator, wait for it to dry to a light haze, and wipe the residue with a microfiber towel.
Tire DressingMake no mistake, we're not advocating bling in Car Craft, but tire shine is good stuff. Like paint, the rubber used to make tires also oxidizes and breaks down over time. When that starts to happen, your once-black tires start to turn an unappealing shade of brownish grey. Not cool. Tire dressing shields the rubber from the environment and slows the aging process. We like the stuff made with silicone that you wipe on rather than spray on; that way you avoid coating the wheels with it as well. Pour a few drops on an old cloth or rag and wipe it on the tires.
TrimYou wouldn't want a glossy paint job taking up space next to dull-looking trim, would you? The same polish you use to clean your wheels can often put a shine back into your chrome and stainless trim. Put a small amount on an old towel and wipe until the shine comes back. Oftentimes the towel will be jet black by the time you're done-it's amazing how dirty these parts can get. Some newer cars have rubber and vinyl trim in addition to or instead of chrome trim. We like to use tire dressing on those parts that are more susceptible to environmental damage, especially from sunlight. While you're at it, you can wipe your weatherstripping with tire dressing, too. That will help keep it from drying out and cracking.
MaintenanceThough we've heard of some people who wash their cars every day (not a good idea, by the way), the more realistic method of keeping your car shiny in between washings is to use quick detailer. If the car is dusty, wipe it first with a car duster, spray on the quick detailer, and wipe it dry with a microfiber towel. It's fast and easy. Be sure to use the softest towels possible, though, in order to avoid scratching the paint.
InteriorIt does not take a lot of effort to keep your interior in top shape. But a neglected interior will draw angry looks at cruise night. California Car Duster makes cool, dashboard-sized dusters that you can hide under the seat. Once a month, wipe the dash with a vinyl protectant. It helps keep the dashpad from cracking over time. We prefer the low-gloss products. Metal dashboards and trim also benefit from polish and a coat of wax.
Deep scratches and Machine PolishUnless you keep your car in a bubble, it's only matter of time until the paint gets scratched. No need to panic, though, when that happens. Here's how we took dog toenail scratches out of one of our commuters. (Greg's Nova was too nice to demonstrate on.)
Think of rubbing compound like sanding body filler or primer. You start with a heavy grit and work down to finer grits. The same holds true with rubbing compound, which really is like liquid sandpaper. After applying the compound, you now need to smooth out the area with a less abrasive polish and follow up with a coat of wax. Victory Wax is a new company that is marketing a line of products specially designed to be applied by a random-orbiting polisher. The kit Victory sent us included the polisher, pads, and several bottles of polish, wax, and quick detailer, and we were impressed with the ease of use and quality of the finish when we were done.
'No water has touched Greg's Nova since it was painted. He keeps it garaged and maintains its shine with quick detailer. Here's us mocking up the car wash scene for the photo shoot.
Blown Nova Tech NotesWho: Greg Nicholl, rental manager for John Deere (but this ain't no tractor)What: '72 Chevrolet NovaWhere: Camarillo, California, where he takes the car to to get groceries
Short-block: The car had a 396ci big-block when Greg bought it in 2005, but he quickly swapped in a Chevrolet ZZ502 crate engine with extensive work by Larry Kraszewski of Camarillo Auto Service. At the center spins a forged-steel crankshaft that swings 9.6:1 forged-aluminum pistons and rings on forged-steel connecting rods. A Chevrolet hydraulic roller cam provides 224/234 duration at 0.050 and 0.527/ 0.544-inch intake lift.
Heads: The Edelbrock aluminum heads have 110cc chambers. The stainless-steel Chevrolet valves are 2.25 inches on the intake and 1.88 inches on the exhaust, all actuated with aluminum rocker arms.
Induction and exhaust: A pair of Holley 750-cfm carbs gets high-volume air from an 8-71 supercharger built by The Blower Shop in Santa Clara, California. (Greg's wife went on vacation, and the huffer was in place when she got back. Stuff happens.) But the blower wasn't enough, so Greg had Jim Bassett of Bones Fab in Camarillo add a 200hp NOS Cheater setup that is fed by its own Barry Grant fuel system in addition to the BG 250 fuel system for the carbs, which siphon gas from a Jaz 15-gallon fuel cell. All of the lines are aluminum or braided steel. The exhaust exits through 2 1/4-inch Hooker headers with 4-inch collectors into 3-inch stainless tubing and Hooker mufflers.
Electrical and cooling: Cooling comes from an Edelbrock aluminum water pump that circulates through a Griffin aluminum radiator with twin electric fans. Spark comes from an MSD 7AL box through an MSD billet distributor and coil, MSD wires, and a Powermaster 140-amp alternator that charges an Optima battery. A Moroso 7-quart oil pan is serviced by a Moroso oil pump and pickup.
Paint and body:
Interior: The interior is also set up for racing, with custom seats by Superior Interiors Upholstery in Camarillo, California, Crow five-point harnesses, and an eight-point rollcage. The custom upholstery and door panels were also stitched by Superior Interiors Upholstery, and the gauge package is all Auto Meter, including Pro Comp oil, water, voltage, and fuel monitors as well as a Pro Comp tach. The steering wheel is from Billet Specialties, and the shifter is a Hurst quarter-stick. With the Sony CD/XM radio stereo pounding out sound from an 800-watt amp through speakers in the headrests, Greg can probably even listen to tunes with the big-block running.
Performance: The combination works. The Nova has turned a 10.13 quarter at 130 mph in street attire with no bottle, and the dyno squealed under 870 hp and 850 lb-ft of torque.


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Getting a Teen to Cook
Wouldn't it be great to come home from work and discover that the kids had cooked a wonderful dinner and all I had to do was gush praise and eat? (And maybe do some dishes.) They have a bit more time in the afternoons several days a week than I do. But they prefer to spend their free time playing video games. And when I get home, I have to throw dinner together and pull them away from games. I'm trying to make things more equitable. But I'm not having a lot of luck.
But what if the video game they were playing encouraged them to cook their favorite foods—and taught them how? I recently met with the folks behind GirlsGoGames.com, a casual gaming site that offers free games just for girls, and that's exactly what they told me the idea is behind their game Sarah's Cooking Class.
My daughter already enjoys the quick, casual games at GirlsGoGames.com. So I asked her if she had played Sarah's Cooking Class. Being a teenager, she rolled her eyes and told me that sounded "lame." But then she realized that I was actually suggesting she take a few minutes to play video games. So she quickly changed her tune and volunteered to play it and let me know what she thought.
"That was fun," she told me 20 minutes later. "Can I make sushi for dinner?" California rolls are one of her favorite foods. So, naturally, she had played that recipe. And while playing, she had learned what ingredients she needed to make her favorite meal, how to prep the sushi rice, how to cut the ingredients, and some technique for rolling and serving the rolls.
She gave me a list of ingredients. (The game provides a recipe.) And we are planning to make them together tonight. My hope is that, once she has the ingredients in house and we've been through it once or twice together, she will be willing to do it by herself when I'm too busy.
I know what you are thinking. But I can hope, can't I?
Christina Tynan-Wood writes the Family Tech column for Family Circle, and is the author of "How to Be a Geek Goddess." You can find her at GeekGirlfriends.com. Follow her on Twitter: @xtinatynanwood.


text: Radioactive iodine uptake test is a type of nuclear test performed to evaluate thyroid function. The patient ingests radioactive iodine (I-123 or I-131) capsules or liquid. After a time (usually 6 and 24-hours later), a gamma probe is placed over the thyroid gland to measure the amount of radioiodine uptake in the thyroid gland. The values are then compared.


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- Original Title : The Ridiculous 6
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Talk to your child about the dangers of tobacco, alcohol, and drugs. Knowing the facts will help your child make healthy choices.
Review Date: Tuesday, December 01, 2015
National Health Information Center - NHICU.S. Department of Health and Human Services
This Q&A booklet answers teens' most frequently asked questions about drugs and drug abuse.
Review Date: Wednesday, May 18, 2011
NIH National Institute on Drug Abuse - NIDA
Learn about inhalant abuse, products used as inhalants, common signs and characteristics of an inhalant user, damage and long-term health effects, and more.
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This Web site teaches adolescents ages 11 through 15 (as well as their parents and teachers) on the science behind drug abuse. Find facts on drugs, interactive games, blogs, videos, and real stories of what teens face when turning their lives around.
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The more aware you are of the influences around you, the better prepared you will be to face them, including the pressure to use drugs, pills, and alcohol.
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This page provides a brief look at some prescription medications and other drugs that have the potential for abuse and addiction.
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This contract is designed to facilitate communication between young people and their parents about potentially destructive decisions related to alcohol, drugs, peer pressure and behavior.
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Get the facts about drugs. Learn the effects of common drugs, why people use them, their health risks, and the risks of criminal penalties. Honest drug facts can prevent teen drug use and establish trust between young people and educators.
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Drug Policy Alliance
Learn about 13 categories of drugs, why they are dangerous, how kids and teens use and abuse them, and physical signs of use that kids typically exhibit.
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Find the current list of United States Department of Health and Human Services certified laboratories.
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Learn about some of the most commonly abused drugs.
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Drug and alcohol use can lead to risky behaviors that can increase your exposure to HIV/AIDS. This brochure for African Americans discusses the issue of substance abuse and HIV.
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Find the real facts on how different drugs affect the brain and body.
Abusing prescription drugs can have negative short- and long-term health consequences. Read about the dangers of abusing prescription drugs.
Many college students mistakenly believe prescription medications are safe because they are FDA approved and prescribed by a doctor. But all medications have risks. Recognize the symptoms of prescription misuse and abuse, and get help, if necessary.
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This document explains to parents the dangers of teenagers abusing prescription drugs and over-the-counter (OTC) drugs. Includes warning signs that your child may be using prescription or OTC drugs to get high.
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This guide aims to provide students with a firm foundation to reach out for the help they need, including plenty of facts about what really constitutes a substance use disorder, how they can find the proper resources to get back on a healthy track and expert advice on what to do if addiction becomes a looming prospect.
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This online self-test can help teens decide if they are at risk for developing alcoholism and/or dependence on another drug.
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Presented in question-and-answer format and targeted to teens, this document provides facts about marijuana and its potential harmful effects.
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This booklet offers parents scientific facts about the dangers of marijuana and tips on talking to their children about drug use.
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This series is designed to encourage children in grades five through nine to learn about the effects of drug abuse on the body and the brain.
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Test your knowledge on drugs and drug abuse by taking the interactive National Drug IQ Challenge quiz!
Repeated abuse of opioids can lead to addiction—compulsive drug seeking and abuse despite its known harmful consequences. Learn more about opioids.
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Learn about prescription drug abuse and dangerous health consequences when used incorrectly or by someone other than for whom they were intended.
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Take the time to learn about the potential benefits, the health risks and the many unknowns regarding so-called performance-enhancing drugs such as anabolic steroids, human growth hormone, diuretics, and stimulants.
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More than 30% of prescription painkiller deaths involve methadone, even though only 2% of painkiller prescriptions are for this drug. Find out what you can do to prevent the misuse of Methadone.
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Prescription drug abuse by teens and young adults is a serious problem in the United States. The Partnership for a Drug-Free America is making sure that parents, young adults and teens know the very real risks of misusing medicine.
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This webcast explores alcohol and drug addiction among veterans, post-traumatic stress disorder and other contributing stressors, and the effect of addiction on families. Addiction treatment issues, and the service options available to vets and their families, are discussed too.
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These six practices include: being a good role model, knowing your child's friends, setting boundaries, having ongoing conversations with your child about drugs and alcohol, and more.
It's important to understand the facts about steroids, their side effects, and what can drive kids to try them. Being aware of the kinds of pressures kids deal with in sports can help you make sure that your child isn't at risk.
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The Nemours Foundation
Find publications offering information on substance abuse and mental health issues, treatment, prevention, and recovery. Ordering information provided.
Review Date: Thursday, February 21, 2013
This site motivates and equips parents to prevent their children from using drugs and alcohol, and to find help and treatment for family and friends in trouble. Get expert advice and support.
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Learn about the dangers of using hallucinogens.
Steroids are used to treat certain diseases, but some people use them to enhance muscle mass and athletic performance. This fact sheet focuses on teens and steroids, summarizing the side effects and risks associated with steroid use.
Learn about drug addiction and how you can get help.
If you're worried that your son or daughter might be abusing alcohol or drugs, learn the warning signs and how to find help and support for yourself.
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Judgment and decision-making skills are still developing in teens, so their ability to assess risks accurately and make sound decisions about using drugs may be limited. Preventing early use of drugs or alcohol may reduce the risk of progressing to later abuse and addiction.
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Phoenix House Center on Addiction and the Family
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Here is a pony that I had so much fun drawing today. It's on a sweet innocent Pegasus type of pony and I call this tut "how to draw an angel pony", step by step. This pony concept was so incredibly fun to create and instead of the Skrillex being one of my fav, this one definitely takes the cake. I just know that all you pony lovers will fall head over heels for this angel even though it is of an animal instead of an actual human. The colors, the facial expression and even the body pose all comes together fantastically in this drawing. Even my seventeen year old brother said she was a pretty pony. I didn't add a cutie mark because she is an angel. To me angels are pure, innocent and full of life even though though they are no longer from our world. I think I captured how beautiful angels really are with this lesson so I do hope you enjoy drawing an angel pony too. I will be back later with some more drawing fun that has everything to do with some new superheroes that you will be seeing soon in theaters. Adios people and have a peaceful day!
DragoArt members upload artwork and drawing tutorials! They are also allowed to leave comments on tutorials, profiles, etc. Many more features, as well; it's way better than just being a boring guest! Register Now!


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MailChimp has been around since 2001. With millions of users sending campaigns to hundreds of millions of recipients, we're bound to get abuse reports every now and then. We take abuse reports seriously, and we go to great lengths to prevent abuse within our system.
How MailChimp prevents and combats abuse
We have a team of human reviewers, who approve new MailChimp accounts and detect abuse within our system. Our staff uses a variety of criteria to evaluate accounts, ranging from the obvious WHOIS and IP information, to some not–so–obvious behavioral patterns.
We require all users to agree to our Terms of Use before setting up a MailChimp account, and again before importing any existing customer lists into their accounts.
Our abuse-prevention initiative, Omnivore, keeps our system clean by predicting bad behavior in campaigns before they even get out the door.
We offer customizable signup forms for customers who are starting from scratch with MailChimp and don't have a list of customers to import. These signup forms only use the double opt–in method, which keeps prank signups out and stores opt–in proof for every subscriber (like IP address and date/time stamps).
We automatically insert a one–click unsubscribe link in every campaign sent from our system.
We'll allow seven soft bounces for an email address with no subscriber activity and up to 15 soft bounces for subscribers with previous subscriber activity before converting a soft bounce into a hard bounce.
How we educate customers
We keep our users updated on the latest best practices, tips, and email etiquette with our blog and customer newsletters.
Our guides help users learn their way around MailChimp and email marketing in general.
Throughout MailChimp's user interface (when sending campaigns, setting up lists, and designing templates), we provide customers with links and background information to help them understand email etiquette and spam laws.
How we deal with issues
We embed every email campaign sent from our servers with a Campaign ID, so recipients can easily report abuse to MailChimp. When we receive complaints through our abuse form, we investigate immediately. If the campaign or user account appears suspicious in any way, we'll suspend the account during the investigation.
We're registered with major ISPs and anti-spam authorities to receive automated feedback loop alerts when any of our users' recipients report abuse. When we're able to parse those alerts, we remove the recipient from the user's list. If the reports exceed a certain threshold, we send a warning to the user. If the warnings exceed a reasonable threshold, we suspend the user's account and investigate. Most ESPs and ISPs say a reasonable threshold for abuse complaints is 0.1 percent, which means 1 out of every 1,000 people reported your campaign as junk. Because of the sheer volume of emails sent from our IPs, and because most of our IPs are shared across multiple users, our threshold is stricter than that.
Report Email Abuse
If you'd like to report an abusive campaign, please use the form below, including full headers. The full header information can be found using instructions in this article. Since every email application is different, you might have to refer to your help files. Usually, if you do a search for "full email headers" or "full message headers," you'll find the instructions you need.
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text: ShareAbout AdministrationPresident | Past Presidents | Governing Boards The administration of Rivier University's various academic, service, and business operations is overseen by a close-knit network of professionals dedicated to the spirit and mission of the Catholic university. Their goal is, first and foremost, to serve students, and provide a caring atmosphere of academic excellence, spiritual guidance, and professional preparation. They also recognize the University's role as a cultural and intellectual resource for the city, the state, and the region. President Sr. Paula Marie Buley, IHMPresidentMolloy Hall(603) 897-8202 Sr. Paula Marie Buley, IHM President Molloy Hall (603) 897-8202 A member of the Sisters, Servants of the Immaculate Heart of Mary, Immaculata, PA, Sister Paula brings to Rivier more than twenty-five years of experience in higher education administration. View biography President's Cabinet Karen CooperVice President for University AdvancementMadeleine Hall(603) email@example.com View biography Karen SchedinVice President for Enrollment ManagementMadeleine Hall(603) firstname.lastname@example.com View biography Kurt StimelingVice President for Student AffairsDion Center(603) firstname.lastname@example.com View biography Douglas W. Howard, Ph.D.Vice President for Academic AffairsAdrienne Hall(603) email@example.com View biography Brent WinigerVice President for Finance and AdministrationMolloy Hall(603) email@example.com View biography


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Biennial's hard hat launch
It's been 50 years since the McNichols Building has been open to the public, and last week several hundred civic leaders were treated to a mid-project look at the handsome Greek Revival structure that will be the principal venue for Biennial of the Americas, a month-long "World's Fair of art and ideas" expected to once again put Denver in the international spotlight.
Biennial of the Americas opens July 1, and the 28,000-square-foot McNichols Building will host "The Nature of Things," central exhibit in the comprehensive showcase of what lead curator Paola Santoscoy describes as "never before seen contemporary arts and cultural programming from countries thoughout the Americas."
Mayor John Hickenlooper told guests that the Biennial will be "The most important international event held here since the Summit of the Eight. The best way to build bridges of understanding is through culture, and the Biennial will deepen our connection to our neighbors and work to build a shared vision for the hemisphere."
But beyond all of that, Hickenlooper said, the celebration will "Put this magnificent building back into public use. It will breathe life back into Civic Center Park, and that is very important for Denver."
The McNichols Building began as a Carnegie Library and then was used for municipal office space.
"The empty interior shell of the McNichols Building will be the hub of the Biennial of the Americas, demonstrating, in the short-term, the kind of cultural programming and energy this building could inspire," adds Lindy Eichenbaum-Lent, who heads the Civic Center Conservancy.
Blake Skinner, Chris Frampton, Christy Owen, Jill Dines and Marcela de la Mar chaired the Hard Hat Gala; honorary chairmen were Mexican Consul Eduardo Arnal, Canadian Consul Dale Eisler and Hickenlooper.
Working with a bare-bones budget, Bradley Joseph of Silver Spur Productions enlisted a cadre of volunteers to make the empty interior more party-friendly. The Museum of Outdoor Arts, members of the Book Babes book club and artist Lonnie Hanzon all pitched in. "Putting this together was like one of those design-on-a-dime reality shows," Joseph confided. "But you've got to admit it looks pretty good."
Mezcal, Great Northern Tavern, Famous Dave's and Three Tomatoes all supplied food, and the entertainment included music by DJ RIPM and DJ Shake One — plus a surprise appearance by the guerilla concert band Boba Fete.
Comfortable clothing was encouraged and several of the 494 guests were costumed according to the theme. Lois Paul, for example, wore an orange reflective vest, rhinestone-studded safety goggles and a feather boa ("For good measure," she said). Her purse: A hard hat carried upside down.
Air Force Academy physics professor Mark Mayer secured an oversize pinwheel to the top of his hard hat.
Renovation architect Mike Moore was there, along with several members of the Denver City Council, City Auditor Dennis Gallagher, state Sen. Chris Romer and such civic figures as Kevin Patterson, James Mejia, Jim Polsfut, Elbra Wedgeworth, Fabby Hillyard, Jayne Buck, Donna Good, Erin Trapp, Jill Crow, Tom Botelho, Zee Ferrufino, Jose Mercado, Lonnie Hanzon, Tom Gougeon, Cynthia Madden Leitner, Doug Jackson, Lee McIntyre, Luella Chavez D'Angelo, Elaine Asarch, Dr. Dean Prina and Myles Mendoza.
Also, Paul Esserman, Dave McKlveen, Deidre Toltz, Matt Keeney, Amy Harmon, Felicia Diamond, BJ Dyer, Guenther Vogt, Peggy Beck, Jonathan Alpert, Will LaBahn, Chris Meza, Brian Jacobson, Tim Connors, Bobbi Walker, Tracy Shaffer and Veronica Montoya.
Joanne Davidson: 303-809-1314 or firstname.lastname@example.com; also, GetItWrite on Twitter


text:
What I mean by not that intelligent is that, even the most "intelligent" christian is less intelligent than an atheist who knows what he/she doesn't believe.
Am I being wrong, or silly?
Views: 700
There are at least two types of christians familiar to me;
1. The mass of mentally inferior people who believe in a God and eternal life, the Bible, the supernatural and the church.
2. Intelligent people who understand science, atheism and nature but nonetheless see the Christian church as providing a moral code and social order to the masses, without which society, law and order would fall apart.
Napoleon Bonaparte, an Atheist, fell into the second category.
Nulle société ne peut exister sans morale. Il n'y a pas de bonne morale sans religion. Il n'y a donc que la religion qui donne à l'Etat un appui ferme et durable.
Napoleon Bonaparte
Following Napoleon's lead (the avatar, not the historical figure), there certainly are mentally inferior people for whom religion is attractive, though there are those in our midst as well. It's the second type that i find the most infuriating, otherwise intelligent people who believe in science and don't take the Bible or their religious holy texts literally and yet remain religious. i think this is done mainly out of convenience, and it demonstrates a real laziness on their parts and a lack of intellectual honesty, but it doesn't make them stupid by any means. Actually i think there might be something to be said for the argument that such people have to be exceedingly smart to figure out ways to retain their obviously-false beliefs in the face of overwhelming evidence. I look at Obama as a prime example. He's clearly brilliant, he's got a powerful mind capable of doing specific sorts of tasks, but when it comes to his entire philosophical worldview, he just hasn't applied his massive intellect to the task. There seem to be a great many such people in politics and many other professions as well, people who I recognize have probably got it over me in pure smarts, but just don't feel like bothering when it comes to the deepest questions. I think most people just don't see the practical uses of philosophy.
There is a difference I think between kinds of intelligence, I know people who are considered highly intelligent and accomplished who are believers. It seems to me one can be academically inclined without being intellectually inclined. Give it some thought, look about you at the people in your life. It is also the path of least resistance, all you have to do is believe, you don't have to read all them hard books--in fact, why don't you get rid of your books---come to Jesus--lol!!
I had a boss when I worked for the Department of the Navy in engineering that was a devout xtian. He would be the first to tell you about his intelectual superiority. I knew several of us brother Atheists, (how can you be an engineer and not be an Atheist?), who thought otherwise. When your boss tells you that Noah was not a legend, (yes exact words), how can you see any credibility in anything else he says?
The point I am trying to make is that I firmly believe that there is some sort of brain deficite in educated religious people. As Carl Sagan said, "once you see the logic and reason of science, you can't go back unless you have a brian injury". That means to me that xtians have some sort of inherant brain damage.
You did ask for my opinion.
I'm just having fun here, just joking around, but I couldn't resist:
You aren't exactly helping your case when you misspell "intelectual", "defecite", "brian", and "inherant". ;-)
That is most definitely the answer, its all in the spelling--lol!!
OK, that's why engineers love spell-check! Next time I'll write it in something else, then cut-and-paste.
Not this engineer. I'm a spelling and grammar nazi!
I would point out that spell check routines are knot proofreading.
I find myself making a split-second assumption that someone who makes it known to me that he is a Christian, believes in god, goes to church, prays, or subscribes to any of the nonsense, that that person is somehow suffering from a mental and psychological defect. Right or wrong, I find myself judging them immediately. Like I said, this is usually a split-second reaction when the topic is first presented. Most of the time, I'm able to continue my interaction with such a person in a civil and respectful way.
The most offensive and clearest evidence for intellectual inferiority of most believers is their tendency to be completely ignorant of the fact that not everyone is one of them. Further, I find that they fail to recognize that most (and I do mean "most") atheists are very well-informed, intelligent people who have come to their world view in a rational and realistic way. Instead, the assumption is often made that people are only atheists because they haven't yet experienced god or read the Bible.
I think there is a case to be made that those who choose favor religious belief over rational thought are either (a) mentally incapable of complex thought and deep contemplation, (b) mentally lazy and ignorant of the potential of the brain (and combined brains of thinking people) to make this world a better place, or (c) as Phoenix-Wanderer said in the earlier post, "exceedingly smart to figure out ways to retain their obviously-false beliefs in the face of overwhelming evidence."
While I don't consider xtians to be 'less intelligent', I do see it as a 'brain blockage'. It seems that some kind of sponge has blocked the open paths of their mind. Though, I do see atheists as being superior in the sense that we do not have this 'blockage' and we see reality and life for what it really is.
Hi, I think even if one were to grant that otherwise smart people still are believers, it begs the question as to why they would choose to do so. I think the idea of an eternal life, and some higher power watching out after you and rewarding you for good deeds-is just too iresistable for even some of the most intelligent people-they simply choose to "suspend their beliefs" in more rational things.Every time I start to argue with my very Christian wife about my lack of belief, I always bring up the age of the earth and how long mankind has been here. I always use that one, as it is so clear cut that the bible is so dead wrong about these things, and yet she refuses to take the bait-she accuses me of "playing games" and she just won't get into that kind of argument.I try to tell her these are not games-these are real serious issues, and if her beliefs are so right, they should stand up to these sorts of challenges. At that point, she usually just gives me a condescending wave of the hand, signaling she is "done".So there you have it, in a nutshell- she, and most like her, simply don't want to accept anything that might destroy the wonderful world they have created for themselves. And nothing, I am afraid, will ever change that, at least for her.
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How to make Crochet Baby Dress - Solomon's Knot
There are a couple of ways to make the dress larger or smaller.
2. You can add a couple more stitches to the under arm of the yoke. You could use 6 or 7 chains or chainless foundations stitch if you wanted to make the chest larger.
The chain can be used instead of the chainless foundation.
Pattern by Teresa Richardson
Video Tutorial:
Crochet Baby Dress - Solomon's Knot
Chainless Half Double Crochet Foundation
40 Chainless HDC or 42 Chains, HDC in each chain.
The foundation row was not counted as a row in the video. It is a row, however I am leaving the instructions so they match the video.
Row 1: CH 2, *HDC in next ST, 2 HDC in next ST, continue across from *, turn (60 half double crochet)
Row 2: CH 2, HDC in ea ST across, turn (60 half double crochet)
Row 3: CH 2, *Hdc in next ST, 2 HDC in next ST, continue across from *, turn (90 half double crochet)
Row 4-5: CH 2, HDC in ea ST across, turn
Row 6: CH 2, *HDC in next 2 STs, 2 HDC in next st, continue across from *, turn (120 half double crochet)
Row 7: Add a marker to the 40th stitch from each edge. CH 1, HDC across next 16 Sts(Back Right),5 Chainless HDC ,SK 24 HDC(Right Arm Hole), HDC Across Front leaving the remaining 40 Sts for the left arm hole and back,5 Chainless HDC ,SK 24(Left Arm Hole), HDC across 16 Sts(Left Back). NOTE*- You can use a chain 5 if you are not familiar with the chainless foundation stitches.
Row 8: 2 Solomon's Knot, SK 2 HDC, SC in next, continue across, turn
Row 9: 3 Knots, *sc on each side of the center of previous knot. 2 Knots, SC on each side of previous knot. Work in a continual round for length of project.
Arm Edging: Attach yarn to armhole. Single Crochet evenly around the armhole opening, slip stitch in beginning SC. Cut yarn, secure, and sew in tail.
Right Back Opening Edging: Attach Yarn, *SC, CH 2, SK 2, SC in next(Button Hole Opening) SC in next 4 Sts, Repeat from * for the next button hole. SC in Rem Sts. CH 1 Turn, SC in ea SC and CH SP. Cut yarn and sew in.
Left Back Opening: Evenly SC 2 rows along edge. Cut yarn and sew in tail. Align buttons with holes and sew on.
Neck Edging:Attach yarn to neck edge. Single Crochet evenly around the neck opening. Once you get to the other edge, cut yarn, secure, and sew in tail.
How to Crochet Baby Dress - Solomon's Knot
How to Crochet Tips


text:
sarbru on Family Tree Circles
view: full | list
Journals and Posts
Mcloughlin, McLaughlin, Brown, Henderson, Stewart .All from Ireland
Searching for William McLoughlin /McLaughlin and Susan Brown. Not sure if they married in Ireland and emigrated to Philadelphia or met and married in USA. Children returned to Ireland early 1900's, at a very young age ,ito be reared in Northern Ireland, possibly Londonderry. Unknown whether Susan and possbly Willam as well, died in US.
My grandfather William, was one of the children. He fought in WW1 and then came to Scotland and married my gran in 1920 and never returned to Ireland. I know there was one other brother. There may have been more siblings but I am not sure.
Anyone out there recognise these names?
- Displaying 1-1 of 1 Journals
- 1
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Meet the Peregrine Team
The recovery of the Peregrine can be credited to the countless individuals and organizations that have supported Peregrines throughout the years. Most important are the people that work in buildings where Peregrines nest or the neighbors in the high-rise next door that have a view of the eyrie. These folks spend hours keeping track of the birds and recording their progress.
For the Chicago Peregrine Program, the list of invaluable contributors is too numerous to name, but we'd like to express our deep appreciation to everyone for your continued support of the Peregrines. Because of you, we can celebrate the Peregrine's recovery.
Mary Hennen is the Collections Assistant in the Bird Division at the Field Museum. In addition to her regular duties of caring for the ornithological collections, she directs the Chicago Peregrine Program. Mary has been involved with Peregrines since 1989 and took over as director in 1990. Work with Peregrines involves banding young, retrieving injured birds, and monitoring wild breeding pairs in Illinois. In addition, because of her interest in raptors, Mary has obtained two live, permanently disabled birds she uses for educational programs. One is a Peregrine, the other is a Red-tailed Hawk. Always a critical part in the recovery of any species is public educational programming that focuses on the importance of the species, as well as its biology and role in the environment. Check out the Illinois Peregrine Facebook page.
Stephanie Ware is a research assistant at the Field Museum. She has worked for Birds, Insects and Botany. She began working with the Chicago Peregrine Program in 2006. Initially, she monitored the Metropolitan Correctional Center nest in downtown Chicago. Over time, her duties have expanded to include other nests in the metro region, emphasizing the identification of nesting adults. In March of 2007, Stephanie created a group called Midwest Peregrine Falcons on the photo sharing website Flickr with the goal of providing a place for photographers across the country to submit their photographs of peregrine sightings in the Midwestern United States. She also has many of her own Peregrine photos on Flickr as well.
Josh Engel is a research assistant in the Field Museum's Bird Division. One of his earliest Peregrine memories is finding the winter roost of the Evanston falcons during a Christmas Bird Count in 1997. He first banded a Peregrine as a Field Museum intern in 2002. His research focuses on genetics and conservation of tropical birds and he is active in the Chicago area birding community.


text: People have been trying to say, for years, that there is something wrong with the church; members in this ring included. This ring not only includes such articles, but for unity of faith, also provides scriptural evidence that the modern day religion of Christianity is not the Christian faith of the Bible. And even if we only know in part and prophesy in part (1 Cor. 13:9); come, consider whatever part you can receive and how you can use that to help in getting your church back on track.


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Jump to navigation Jump to search
The "Papers" page is a library of up to date research papers on subjects which you may find useful when creating articles for us, or doing your own studies.
In addition, there is also some helpful instructions on several ways to gain access to any papers you may need.
- If you have any questions about our library you should contact our lead research librarian LilianaUmbra, who is responsible for managing research requests and this pages content.
- 1 Finding papers
- 2 Getting access
- 3 Transition related healthcare
- 3.1 Bone Density
- 3.2 Reproductive Health
- 3.3 Hormone Replacement Therapy
- 3.4 Risk Analysis
- 3.5 Evaluation and Assessment
- 3.6 Body Contouring
- 3.7 Facial Modification- General
- 3.8 Interpersonal Relationships & Sexuality
- 3.9 Masculinization
- 3.10 Feminization
- 4 Standards Of Care & Practice Guidelines
- 5 History
- 6 Neuroscience
- 7 Drugs
- 8 Biological Mechanisms
- 9 Methods
Finding papers
- Google Scholar indexes articles, shows citations and "cited bys", impact factor etc.
- Pubmed offers more granular search options.
Getting access
Journal articles are frequently paywalled, requiring an obscene ~$40 per article to see anything besides their abstracts. Here's some ways around:
- If you're a student, your university should have journal access for all IPs on its network. If you make friends with a student, you could ask to borrow their login.
- Even if you're not a student, you can often get a library card at a university library. University library computers will have journal access, so if the library is open to the public you can surf there and save articles to a USB stick.
- Sci-Hub is a proxy that circumvents paywalls for journal access. You can tack .sci-hub.mn on the end of the domain name for a URL you want to access. For instance, if you wanted to go to http://nature.com/some/article.html, change it to http://nature.com.sci-hub.cc/some/article.html. Note that sci-hub is frequently under attack and the legality of using it varies by region, ymmv.
- Library Genesis has a repository of scientific papers. Unlike Sci-Hub, it does not let you access papers that don't already exist in the LibGen repository. However, it is a useful backup if Sci-Hub is down, as Sci-Hub stores a copy of every paper it downloads to LibGen.
- Using Sci-Hub Links extension for Chrome and Firefox can be used to automatically translate DOI to sci-hub links
- The Scholar subreddit lets you post requests for articles. Volunteers will find and upload articles for you, bypassing the paywall.
- Arxiv hosts free pre-publication articles, but very few in the biology realm.
- Due to the volatile nature of which domains are working for sci-hub currently, if any links are broken simply replace the domain of the link with a working one. .tw works as of 12/07/2018.
Bone Density
- Effect of Sex Steroids on the Bone Health of Transgender Individuals: A Systematic Review and Meta-Analysis (November 2017)
- Bone Mineral Density Increases in Trans Persons After 1 Year of Hormonal Treatment: A Multiscenter Prospective Observational Study (May 2017)
- Effect of pubertal suppression and cross-sex hormone therapy on bone turnover markers and bone mineral apparent density (BMAD) in transgender adolescents (February 2017)
Reproductive Health
Hormone Replacement Therapy
- Proandrogenic and Antiandrogenic Progestins in Transgender Youth: Differential Effects on Body Composition and Bone Metabolism (June 2018)
- Gender-Affirming Pharmacological Interventions for Youth With Gender Dysphoria: When Treatment Guidelines Are Not Enough(November 2017)
- Changes in hormonal and metabolic parameters in transgender subjects on cross-sex hormone therapy: A cohort study (October 2017)
- Efficacy and Safety of Gonadotropin-Releasing Hormone Agonist Treatment to Suppress Puberty in Gender Dysphoric Adolescents (July 2016)
- Mad men, women and steroid cocktails: A review of the impact of sex and other factors on anabolic androgenic steroids effects on affective behaviors (February 2016)
- A Systematic Review of the Effects of Hormone Therapy on Psychological Functioning and Quality of Life in Transgender Individuals (January 2016)
- Hormone therapy in transgender adults is safe with provider supervision; A review of hormone therapy sequelae for transgender individuals (June 2015)
Risk Analysis
- Gender-affirming hormone therapy and the risk of sex hormone-dependent tumours in transgender individuals-A systematic review. (August 2018)
- Sex Steroids and Cardiovascular Outcomes in Transgender Individuals: A Systematic Review and Meta-Analysis (November 2017)
- Is Type 1 Diabetes Mellitus More Prevalent Than Expected in Transgender Persons? A Local Observation (September 2017)
- Cardiovascular Disease Among Transgender Adults Receiving Hormone Therapy: A Narrative Review (August 2017)
- Gender Dysphoria and Co-Existing Psychosis: Review and Four Case Examples of Successful Gender Affirmative Treatment (April 2017)
Evaluation and Assessment
- Evaluation and Treatment of Gender Dysphoria to Prepare for Gender Confirmation Surgery. (June 2018)
Body Contouring
Facial Modification- General
Interpersonal Relationships & Sexuality
- An Exploratory Study of Predictors of Relationship Commitment for Cisgender Female Partners of Transgender Individuals. (October 2018)
Hormone Replacement Therapy
- Testosterone undecanoate and testosterone enanthate injections are both effective and safe in transmen over 5 years of administration. (July 2018)*
- Exogenous Testosterone Does Not Induce Or Exacerbate The Metabolic Features Associated With PCOS Among Transgender Men (June 2018)
- Pharmacokinetics, safety, and patient acceptability of subcutaneous versus intramuscular testosterone injection for gender-affirming therapy: A pilot study (March 2018)
- Severe Secondary Polycythemia in a Female-to-Male Transgender Patient While Using Lifelong Hormonal Therapy: A Patient's Perspective (February 2018)
- Cross-sex testosterone therapy in ovariectomized mice: addition of low-dose estrogen preserves bone architecture (November 2017)
- Relationship between testosterone in serum, saliva and urine during treatment with intramuscular testosterone undecanoate in gender dysphoria and male hypogonadism (November 2017)
- The Response of the Menstrual Cycle to Initiation of Hormonal Therapy in Transgender Men (October 2017)
- Effects of testosterone therapy on BMI, blood pressure, and laboratory profile of transgender men: a systematic review (September 2017)
- Subcutaneous Injection of Testosterone Is an Effective and Preferred Alternative to Intramuscular Injection: Demonstration in Female-to-Male Transgender Patients (July 2017)
- Consecutive lynestrenol and cross-sex hormone treatment in biological female adolescents with gender dysphoria: a retrospective analysis (February 2016)
- High-Dose Testosterone Treatment Increases Serotonin Transporter Binding in Transgender People (October 2015)
- Antimüllerian hormone levels decrease in female-to-male transsexuals using testosterone as cross-sex therapy (May 2015)
- Testosterone treatment and MMPI-2 improvement in transgender men: a prospective controlled study (February 2015)
- Testosterone replacement elevates the serum uric acid levels in patients with female to male gender identity disorder (September 2013)
- Dose-response analysis of testosterone replacement therapy in patients with female to male gender identity disorder (October 2012)
- Associations between transition-specific stress experience, nocturnal decline in ambulatory blood pressure, and C-reactive protein levels among transgender men (January 2012)
- Safety aspects of 36 months of administration of long-acting intramuscular testosterone undecanoate for treatment of female-to-male transgender individuals (September 2009)
Genital Reassignment Surgery
- Total Phalloplasty With Latissimus Dorsi Musculocutaneous Flap in Female-to-male Transgender Surgery. (October 2018)
- Outcomes of inflatable penile prosthesis insertion in 247 patients completing female to male gender reassignment surgery (January 2018)
- Total vaginectomy and urethral lengthening at time of neourethral prelamination in transgender men(November 2017)
- Double flap phalloplasty in transgender men: Surgical technique and outcome of pedicled anterolateral thigh flap phalloplasty combined with radial forearm free flap urethral reconstruction (November 2017)
- How Big is Too Big? The Girth of Bestselling Insertive Sex Toys to Guide Maximal Neophallus Dimensions (November 2017)
- A Longitudinal Study of Motivations Before and Psychosexual Outcomes After Genital Gender-Confirming Surgery in Transmen (November 2017)
- Phalloplasty with Urethral Lengthening: Addition of a Vascularized Bulbospongiosus Flap from Vaginectomy Reduces Postoperative Urethral Complications (October 2017)
- MatriDerm Decreases Donor Site Morbidity After Radial Forearm Free Flap Harvest in Transgender Surgery (October 2017)
- Outcomes After Phalloplasty: Do Transgender Patients and Multiple Urethral Procedures Carry a Higher Rate of Complication? (October 2017)
- Combined hysterectomy and mastectomy surgery for transgender patients in an integrated health care setting (August 2017)
- Effects of long-term exogenous testosterone administration on ovarian morphology, determined by transvaginal (3D) ultrasound in female-to-male transsexuals (July 2017)
- An Update on Genital Reconstruction Options for the Female-to-Male Transgender Patient: A Review of the Literature (March 2017)
- Robot-assisted laparoscopic colpectomy in female-to-male transgender patients; technique and outcomes of a prospective cohort study (November 2016)
- The 2011 WPATH Standards of Care and Penile Reconstruction in Female-to-Male Transsexual Individuals (May 2012)
- Clinical applications of the pedicled anterolateral thigh flap in penile reconstruction (January 2011)
Reproductive Health
- Could the female-to-male transgender population be donor candidates for uterus transplantation? (December 2017)
- From erasure to opportunity: a qualitative study of the experiences of transgender men around pregnancy and recommendations for providers (November 2017)
- Hysterectomy for the Transgendered Male: Review of Perioperative Considerations and Surgical Techniques with Description of a Novel 2-Port Laparoscopic Approach (September 2017)
- Uterine and ovarian changes during testosterone administration in young female-to-male transsexuals (October 2016)
Vocal Therapy
- First Female-to-Male Facial Confirmation Surgery with Description of a New Procedure for Masculinization of the Thyroid Cartilage (April 2017)
- Voice deepening under testosterone treatment in female-to-male gender dysphoric individuals (April 2016)
Top surgery and binding
- Chest Reconstruction and Chest Dysphoria in Transmasculine Minors and Young Adults: Comparisons of Nonsurgical and Postsurgical Cohorts (May 2018)
- Modified Nipple Flap with Free Areolar Graft for Component Nipple-Areola Complex Construction: Outcomes with A Novel Technique for Chest Wall Reconstruction in Transgender Men (May 2018)
- Subcutaneous mastectomy in female-to-male transsexuals: Optimizing perioperative and operative management in 8 years clinical experience (September 2017)
- Chest reconstructive surgeries in transmasculine youth: Experience from one pediatric center (July 2017)
- A Review of 101 Consecutive Subcutaneous Mastectomies and Male Chest Contouring Using the Concentric Circular and Free Nipple Graft Techniques in Female-to-Male Transgender Patients (June 2017)
- Health impact of chest binding among transgender adults: a community-engaged, cross-sectional study (October 2015)
Hormone Replacement Therapy
- Low estrogen doses normalize testosterone and estradiol levels to the female range in transgender women (April 2018)
- Spectrum of findings in orchiectomy specimens of persons undergoing gender confirmation surgery(March 2018)
- Predictive markers for mammoplasty and a comparison of side effect profiles in transwomen taking various hormonal regimens (December 2012)
Risk Analysis
- Presentation of a meningioma in a transwoman after nine years of cyproterone acetate and estradiol intake: case report and literature review. (June 2018)
- Impact of cross-sex hormone therapy on bone mineral density and body composition in transwomen (June 2018)
- A case of first-onset psychosis and repeated relapses secondary to discontinuation of non-prescription estrogen replacement therapy in a transgendered female (April 2016)
- Bilateral non-arteritic ischemic optic neuropathy in a transsexual woman using excessive estrogen dosage (February 2014)
- Development of systemic lupus erythematosus in a male-to-female transsexual: the role of sex hormones revisited.(November 2013)
Genital Reassignment Surgery
- Postoperative complications of male to female sex reassignment surgery: A 10-year French retrospective study.(September 2018)
- Davydov Procedure for Augmenting Vaginal Length in a Postsurgical Male-to-Female Transgender Patient(July 2018)
- Sexual Function After Shallow and Full-Depth Vaginoplasty: Challenges, Clinical Findings, and Treatment Strategies- Urologic Perspectives (July 2018)
- Does Depth Matter? Factors Affecting Choice of Vulvoplasty Over Vaginoplasty as Gender-Affirming Genital Surgery for Transgender Women (June 2018)
- Predictors of Patient Satisfaction and Postoperative Complications in Penile Inversion Vaginoplasty (June 2018)
- Vaginal reconstruction with the modified rectosigmoid colon: surgical technique, long-term results and sexual outcomes (March 2018)
- Complications of the neovagina in male-to-female transgender surgery: A systematic review and meta-analysis with discussion of management(March 2018)
- Surgical Satisfaction, Quality of Life, and Their Association After Gender-Affirming Surgery: A Follow-up Study (February 2018)
- Autologous Buccal Micro-Mucosa Free Graft combined with Posterior Scrotal Flap Transfer for Vaginoplasty in Male-To-Female Transsexuals: A Pilot Study (February 2018)
- Neovaginal Construction with Pelvic Peritoneum: Reviewing an Old Approach for a New Application (November 2017)
- Male-to-Female Sex Reassignment Surgery using the Combined Vaginoplasty Technique: Satisfaction of Transgender Patients with Aesthetic, Functional, and Sexual Outcomes (November 2017)
- Gender Confirmation Surgery Using the Pedicle Transverse Colon Flap for Vaginal Reconstruction: A Clinical Outcome and Sexual Function Evaluation Study (November 2017)
- Penile Inversion Vaginoplasty with or without Additional Full-Thickness Skin Graft: To Graft or Not to Graft? (March 2017)
- MR imaging in patients with male-to-female sex reassignment surgery: postoperative anatomy and complications (April 2017)
- Age Is Just a Number: WPATH-Affiliated Surgeons' Experiences and Attitudes Toward Vaginoplasty in Transgender Females Under 18 Years of Age in the United States (April 2017)
- Patient-Reported Esthetic and Functional Outcomes of Primary Total Laparoscopic Intestinal Vaginoplasty in Transgender Women With Penoscrotal Hypoplasia (September 2016)
- Clinical Characteristics and Management of Neovaginal Fistulas After Vaginoplasty in Transgender Women (June 2016)
- Testicular Functions and Clinical Characterization of Patients with Gender Dysphoria (GD) Undergoing Sex Reassignment Surgery (SRS)(November 2015)
Reproductive Health
- Andrology of male-to-female transsexuals: Influence of cross-sex hormone therapy on testicular function(September 2017)
- Effects of Elevated β-Estradiol Levels on the Functional Morphology of the Testis - New Insights(January 2017)
Facial Feminization Therapy
- Thyroid chondroplasty: Smoothing the thyroid cartilage— A retrospective study of thyroid chondroplasty for feminine neck appearance (August 2017)
Vocal Therapy
- Effects of Gender-confirming Pitch-raising Surgery in Transgender Women a Long-term Follow-up Study of Acoustic and Patient-reported Data. (August 2018)
Standards Of Care & Practice Guidelines
- Australian standards of care and treatment guidelines for transgender and gender diverse children and adolescents (June 2018)
- Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline (November 2017)
- Taking Charge: A Handbook For Health Care & Social Service Providers Working With Trans People (2011)
Professional Resources & Patient Care
- ENDOCRINOLOGY FELLOWS' PERCEPTION OF THEIR CONFIDENCE AND SKILL LEVEL IN PROVIDING TRANSGENDER HEALTHCARE. (October 2018)
- Female Pelvic Medicine and Reconstructive Surgery Fellows' Exposure to Transgender Healthcare.(September 2018)
- Ministry to Transgender Teenagers (Part One): Pursuing Awareness and Understanding about Trans Youth.(September 2018)
- Gender dysphoria assessment and action for youth: Review of health care services and experiences of trans youth in Manitoba (May 2018)
- The current status of transgender health education in doctor of pharmacy curricula in North America (March 2018)
- Transgender and Gender-Nonconforming Patients in the Emergency Department: What Physicians Know, Think, and Do (February 2018)
- Supporting and caring for transgender and gender nonconforming youth in the urology practice (June 2017)
- From William's Doll to Jacob's New Dress: The Depiction of Gender Non-Conforming Boys in Children's Picture Books From 1972 to 2014(June 2018)
- A Historical Review of Gender-Affirming Medicine: Focus on Genital Reconstruction Surgery. (August 2017)
- Brain sexual differentiation and effects of cross-sex hormone therapy in transpeople: A resting-state functional magnetic resonance study (October 2017)
- Effects of testosterone treatment on hypothalamic neuroplasticity in female-to-male transgender individuals (August 2017)
- Serum concentrations of brain-derived neurotrophic factor in patients diagnosed with gender dysphoria undergoing sex reassignment surgery. (March 2017)
- Subcortical gray matter changes in transgender subjects after long-term cross-sex hormone administration (December 2016)
- Gender transition affects neural correlates of empathy: A resting state functional connectivity study with ultra high-field 7T MR imaging (September 2016)
- A Structural Magnetic Resonance Imaging Study in Transgender Persons on Cross-Sex Hormone Therapy(August 2016)
- Regional volumes and spatial volumetric distribution of gray matter in the gender dysphoric brain. (May 2015)
- Biorelevant Media Slows the Solution-Mediated Phase Transformation of Amorphous Spironolactone (January 2018)
- Testosterone levels achieved by medically treated transgender women in a united states endocrinology clinic cohort (November 2017)
- Metabolomics for informing adverse outcome pathways: Androgen receptor activation and the pharmaceutical spironolactone (March 2017)
- Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives (February 2017)
- Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disorders(December 2006)
- Transient Elevated Serum Prolactin in Trans Women Is Caused by Cyproterone Acetate Treatment(October 2017)
- Consecutive Cyproterone Acetate and Estradiol Treatment in Late-Pubertal Transgender Female Adolescents (May 2017)
- Is a lower dose of cyproterone acetate as effective at testosterone suppression in transgender women as higher doses? (March 2017)
- Differential Effects of Cyproterone Acetate vs Spironolactone on Serum High-Density Lipoprotein and Prolactin Concentrations in the Hormonal Treatment of Transgender Women. (November 2016)
- Cyproterone acetate vs leuprolide acetate in combination with transdermal oestradiol in transwomen: a comparison of safety and effectiveness (August 2016)
- Preparation and evaluation of a phospholipid-based injectable gel for the long term delivery of leuprolide acetaterrh (June 2016)
- Extended release, 6-month formulations of leuprolide acetate for the treatment of advanced prostate cancer: achieving testosterone levels below 20 ng/dl (November 2015)
- Leuprolide Acetate Inhibits Spinal Cord Inflammatory Response in Experimental Autoimmune Encephalomyelitis by Suppressing NF-κB Activation (October 2015)
- Aqueous stability of leuprolide acetate: effect of temperature, dissolved oxygen, pH and complexation with β-cyclodextrin (October 2014)
- A 6-month depot formulation of leuprolide acetate is safe and effective in daily clinical practice: a non-interventional prospective study in 1273 patients (July 2011)
- Leuprolide Acetate 1-Month Depot for Central Precocious Puberty: Hormonal Suppression and Recovery (March 2011)
- Effectiveness, pharmacokinetics, and safety of a new sustained-release leuprolide acetate 3.75-mg depot formulation for testosterone suppression in patients with prostate cancer: a Phase III, open-label, international multicenter study (April 2010)
- Tibolone reverses the cognitive effects caused by leuprolide acetate administration, improving mood and quality of life in patients with symptomatic uterine leiomyomas (July 2008)
- Equivalent and sufficient effects of leuprolide acetate and goserelin acetate to suppress serum testosterone levels in patients with prostate cancer (May 2008)
- Patterns of hormonal response to the GnRH agonist leuprolide in brothers of women with polycystic ovary syndrome: a pilot study (December 2004)
- Treatment with leuprolide acetate decreases the threshold of the ventilatory response to carbon dioxide in healthy males (December 2004)
- Comparison Between a Single Dose of Goserelin (Depot) and Multiple Daily Doses of Leuprolide Acetate for Pituitary Suppression in IVF Treatment: A Clinical Endocrinological Study of the Ovarian Response(July 2002)
- Serum luteinizing hormone rises within minutes after depot leuprolide injection: implications for monitoring therapy (February 2002)
- Testosterone/bicalutamide antagonism at the predicted extracellular androgen binding site of ZIP9 (December 2017)
- Efficacy of Immediate Switching from Bicalutamide to Flutamide as Second-Line Combined Androgen Blockade (July 2016)
- Interaction mechanism exploration of R-bicalutamide/S-1 with WT/W741L AR using molecular dynamics simulations (December 2015)
- A Randomized Control Trial Comparing the Efficacy of Antiandrogen Monotherapy: Flutamide vs. Bicalutamide (August 2015
- Effects of the ABCG2 and ABCB1 drug transporter polymorphisms on the pharmacokinetics of bicalutamide in humans (January 2015)
- Species-dependent binding of new synthesized bicalutamide analogues to albumin by optical biosensor analysis(February 2015)
- Optical biosensor analysis in studying new synthesized bicalutamide analogs binding to androgen receptor (July 2014)
- The relative bioavailability study and fasting and fed states pharmacokinetics of bicalutamide 50-mg tablets in healthy Chinese volunteers (January 2012)
- Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity (May 2010)
- Activity of Androgen Receptor Antagonist Bicalutamide in Prostate Cancer Cells Is Independent of NCoR and SMRT Corepressors (September 2007
- Bicalutamide Functions as an Androgen Receptor Antagonist by Assembly of a Transcriptionally Inactive Receptor (May 2002)
- Impact of enzalutamide and its main metabolite N-desmethyl enzalutamide on pharmacokinetically important drug metabolizing enzymes and drug transporters (December 2017)
- Absorption, Distribution, Metabolism, and Excretion of the Androgen Receptor Inhibitor Enzalutamide in Rats and Dogs (August 2017)
- Effects of tamoxifen on neuronal morphology, connectivity and biochemistry of hypothalamic ventromedial neurons: Impact on the modulators of sexual behavior (January 2018)
- Tamoxifen a pioneering drug: An update on the therapeutic potential of tamoxifen derivatives (January 2018)
- A Molecular Combination of Zinc(II) Phthalocyanine and Tamoxifen Derivative for Dual Targeting Photodynamic Therapy and Hormone Therapy(August 2017)
- The Effects of Tamoxifen on Plasma Lipoprotein(a) Concentrations: Systematic Review and Meta-Analysis (June 2017)
- Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development (December 2016)
- Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system (August 2016)
- Tamoxifen: an FDA approved drug with neuroprotective effects for spinal cord injury recovery (August 2016)
- Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity (May 2016)
- Tamoxifen for the management of breast events induced by non-steroidal antiandrogens in patients with prostate cancer: a systematic review (August 2012)
- Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study (July 2007)
- Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status (September 2015)
- Synthesis and Characterizaton of Fluorescent 4-Hydroxytamoxifen Conjugates with Unique Antiestrogenic Properties (May 2010)
- Comparative metabolic study between two selective estrogen receptor modulators, toremifene and tamoxifen, in human liver microsomes (October 2015)
- Nano-Targeted Delivery of Toremifene, an Estrogen Receptor-α Blocker in Prostate Cancer (August 2015)
- Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics (June 2012)
- Relevance of the selective oestrogen receptor modulators tamoxifen, toremifene and clomiphene in doping field: endogenous steroids urinary profile after multiple oral doses (November 2011)
- Clinical usefulness of high-dose toremifene in patients relapsed on treatment with an aromatase inhibitor (August 2009)
- Endoxifen, a New Treatment Option for Mania: A Double‐Blind, Active‐Controlled Trial Demonstrates the Antimanic Efficacy of Endoxifen (October 2016)
- Design, Synthesis and Biochemical Evaluation of Novel Selective Estrogen Receptor Ligand Conjugates Incorporating an Endoxifen-Combretastatin Hybrid Scaffold (September 2016)
- Pharmacokinetics of endoxifen and tamoxifen in female mice: implications for comparative in vivo activity studies (October 2014)
- Influence of the Length and Positioning of the Antiestrogenic Side Chain of Endoxifen and 4-Hydroxytamoxifen on Gene Activation and Growth of Estrogen Receptor Positive Cancer Cells (May 2014)
- Structure Function Relationships of Estrogenic Triphenylethylenes Related to Endoxifen and 4-Hydroxytamoxifen (April 2010)
Fulvestrant-3-boronic acid
- Metabolism, pharmacokinetics, and bioavailability of ZB716, a Steroidal Selective Estrogen Receptor Downregulator (SERD)(October 2017)
- Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD) (September 2016)
- Oral bioavailability enhancement of raloxifene by developing microemulsion using D-optimal mixture design: optimization and in-vivo pharmacokinetic study (December 2017)
- Nanostructured lipid carriers for oral bioavailability enhancement of raloxifene: Design and in vivo study (May 2016)
- Effects of raloxifene, hormone therapy, and soy isoflavone on serum high-sensitive C-reactive protein in postmenopausal women (January 2005)
- Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men (December 2017)
- Therapeutic experience with oral finasteride for androgenetic alopecia in female-to-male transgender patients (October 2017)
- Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients (July 2017)
- Opposite effects of dihydrotestosterone and estradiol on apoptosis in the anterior pituitary gland from male rats (March 2016)
Biological Mechanisms
DMRT1/SOX9 + FOXL2/WNT-4/β-catenin
- Antagonistic roles of Dmrt1 and Foxl2 in sex differentiation via estrogen production in tilapia as demonstrated by TALENs (December 2013)
- Sex and the singular DM domain: insights into sexual regulation, evolution and plasticity (February 2012)
- Failure of SOX9 Regulation in 46XY Disorders of Sex Development with SRY, SOX9 and SF1 Mutations (March 2011)
- Aromatase Is a Direct Target of FOXL2: C134W in Granulosa Cell Tumors via a Single Highly Conserved Binding Site in the Ovarian Specific Promoter (December 2010)
- Doublesex- and Mab-3-Related Transcription Factor-1 Repression of Aromatase Transcription, a Possible Mechanism Favoring the Male Pathway in Tilapia (March 2010)
- The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation (June 2009)
- Activation of b-catenin signaling by Rspo1 controls differentiation of the mammalian ovary (February 2008)
- Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells (July 2005)
- SRY, SOX9, and DAX1 expression patterns during human sex determination and gonadal development (March 2000)
Androgen Receptors
- Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer (September 2014)
- Identification of novel androgen receptor antagonists using structure- and ligand-based methods (January 2013)
- Structure-based Virtual Screening and Identification of a Novel Androgen Receptor Antagonist (June 2012)
- Alternative inhibition of androgen receptor signaling: Peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors (June 2010)
- The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells (June 2007)
- The Corepressors Silencing Mediator of Retinoid and Thyroid Hormone Receptor and Nuclear Receptor Corepressor Are Involved in Agonist- and Antagonist-Regulated Transcription by Androgen Receptor (May 2006)
- LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription (July 2005)
- The Androgen Receptor Recruits Nuclear Receptor CoRepressor (N-CoR) in the Presence of Mifepristone via Its N and C Termini Revealing a Novel Molecular Mechanism for Androgen Receptor Antagonists (December 2004)
- Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes (March 2004)
- Antiandrogen Effects of Mifepristone on Coactivator and Corepressor Interactions with the Androgen Receptor (January 2004)
Estrogen Receptors
- Chlorinated biphenyls effect on estrogen-related receptor expression, steroid secretion, mitochondria ultrastructure but not on mitochondrial membrane potential in Leydig cells (March 2017)
- Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity (December 2016)
- A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β (August 2016)
- The Molecular, Cellular and Clinical Consequences of Targeting the Estrogen Receptor Following Estrogen Deprivation Therapy (June 2015)
- Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element (May 2015)
- Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway (July 2014)
- In Vitro and in Vivo Molecular Imaging of Estrogen Receptor α and β Homo- and Heterodimerization: Exploration of New Modes of Receptor Regulation (November 2011)
- High content imaging-based assay to classify estrogen receptor-α ligands based on defined mechanistic outcomes (May 2011)
- A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer (May 2011)
- Unique Ligand Binding Patterns Between Estrogen Receptor α and β Revealed by Hydrogen/Deuterium Exchange (October 2009)
- Selective Estrogen Receptor Modulators 4-Hydroxytamoxifen and Raloxifene Impact the Stability and Function of SRC-1 and SRC-3 Coactivator Proteins (January 2004)
- Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β (March 1999)
- Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase (November 2017)
- Sulfonanilide Derivatives in Identifying Novel Aromatase Inhibitors by Applying Docking, Virtual Screening, and MD Simulations Studies (October 2017)
- High-Throughput Analysis of Ovarian Cycle Disruption by Mixtures of Aromatase Inhibitors (July 2017)
- Six new ergostane-type steroids from king trumpet mushroom (Pleurotus eryngii) and their inhibitory effects on nitric oxide production (November 2016)
- Relationship Between Breast Density and Selective Estrogen-Receptor Modulators, Aromatase Inhibitors, Physical Activity, and Diet (April 2016)
- Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure–Function Perspective (January 2016)
- Synthesis of Triphenylethylene Bisphenols as Aromatase Inhibitors that Also Modulate Estrogen Receptors (December 2015)
- Comparative study on individual aromatase inhibitors on cardiovascular safety profile: a network meta-analysis (September 2015)
- Local Transformations of Androgens into Estradiol by Aromatase P450 Is Involved in the Regulation of Prolactin and the Proliferation of Pituitary Prolactin-Positive Cells (June 2014)
- Dynamics and Flexibility of Human Aromatase Probed by FTIR and Time Resolved Fluorescence Spectroscopy (December 2013)
- Molecular Simulations of Aromatase Reveal New Insights Into the Mechanism of Ligand Binding (August 2013)
- Testosterone-derived estradiol production by male endothelium is robust and dependent on p450 aromatase via estrogen receptor alpha (May 2013)
- Synthesis and Structure–Activity Relationship Studies of Derivatives of the Dual Aromatase–Sulfatase Inhibitor 4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)aminomethyl}phenyl sulfamate (March 2013)
- Development of a new class of aromatase inhibitors: Design, synthesis and inhibitory activity of 3-phenylchroman-4-one (isoflavanone) derivatives (February 2012)
- Aromatase, Estrone Sulfatase, and 17β-Hydroxysteroid Dehydrogenase: Structure-Function Studies and Inhibitor Development (October 2010)
- Diversity of mechanisms involved in aromatase regulation and estrogen action in the brain (January 2010)
- Structural basis for androgen specificity and oestrogen synthesis in human aromatase (February 2010)
- Xanthones from the Botanical Dietary Supplement Mangosteen (Garcinia mangostana) with Aromatase Inhibitory Activity (June 2008)