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SHENYANG, China, June 18, 2014 /PRNewswire/ -- 3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive license with Selecta Biosciences for pegsiticase (Uricase PEG-20), a pegylated recombinant uricase from candida utilis. Pegsiticase has shown the ability to efficiently reduce plasma uric acid levels in gout patients in successful U.S. Phase 1 clinical tests. The exclusive license enables Selecta to develop pegsiticase in patients with refractory and tophaceous gout and apply its immunomodulatory Synthetic Vaccine Particle (SVP) platform to optimize the safety and efficacy profile for patients at risk of immunogenicity. SEL-212 is a novel product that combines Selecta's proprietary SVP with 3SBio's pegsiticase and is designed to be the first non-immunogenic version of uricase.
"Pegsiticase has already shown significant efficacy signals in gout patients and we have the opportunity to develop a novel therapeutic approach with the goal of preventing the inhibitory antibodies and other complications of immunogenicity that have been a significant barrier to the widespread use of uricase-based drugs. With the combination of SVP and pegsiticase, we believe we can dramatically improve treatment for patients with refractory and tophaceous gout," said Werner Cautreels, PhD, President and Chief Executive Officer of Selecta. "Working with 3SBio, we have the potential to fulfill a key medical need expressed by physicians - the first non-immunogenic uricase. 3SBio's strength of enzyme manufacturing combined with Selecta's proprietary antigen-specific tolerance platform will ensure fast progress towards human proof of concept. If successful, Selecta's SVP platform may unlock the full therapeutic potential of many other biologic therapies adversely affected by immunogenicity."
Selecta will work with 3SBio to advance pegsiticase-based therapeutics as potential treatments for refractory and tophaceous gout as well as tumor lysis syndrome, with the ultimate goal of expeditiously moving toward regulatory approvals. Selecta and 3SBio have agreed to work together to achieve clinical proof of concept for SEL-212 and pegsiticase in human clinical trials in their territories; Selecta's territory includes US and all of Europe. Proof-of-concept clinical studies are expected to be initiated in 2015. Additional terms of the exclusive license granted by 3SBio to Selecta are not being disclosed.
"Patients with refractory and tophaceous gout have currently very limited treatment options. Indeed, these patients generally cannot be successfully treated by conventional oral gout drugs," said Dr. Jing Lou, MD, PhD, and CEO of 3SBio. "We are impressed with SVP's potential to greatly expand the safe and effective use of biological therapeutics. Our proven capabilities in manufacturing and development of biological therapeutics combined with Selecta's strong development capabilities and unique SVP platform, promise to be an effective partnership for expanding the use of pegsiticase. Together, we are committed to meeting the significant unmet needs of refractory and tophaceous gout patients."
About Refractory, Tophaceous Gout and Tumor Lysis Syndrome
A painful inflammatory disease caused by elevated plasma uric acid levels, gout affects 2-3 million patients in the United States and more than 10 million patients worldwide. Chronic refractory gout represents approximately 2% of patients, who cannot be effectively treated with available oral therapies. Tophaceous gout is a debilitating condition resulting from painful deposits of uric acid crystals in joints, tendons and surrounding tissue that affects 7-10% of gout patients. Tumor Lysis Syndrome (TLS) appears in approximately 20,000 cancer patients in the United States who have elevated uric acid levels as a result of chemotherapy. For all three indications, oral therapies are not indicated because the mechanism of these oral therapies interferes with the synthesis of uric acid but is ineffective in the breakdown of existing uric acid deposits. Approved uricase enzymes are highly effective for a short course of treatment, but can rapidly lose efficacy due to the formation of anti-drug antibodies. Their clinical use is further restricted due to high risks of allergic reactions.
About SEL-212 and Pegsiticase
Pegsiticase is a pegylated urate oxidase or uricase, an enzyme not present in humans that is highly effective in catalyzing the oxidation of uric acid. Phase 1 studies completed in the United States with a single dose of pegsiticase confirmed safety and efficacy in reducing plasma uric acid levels in refractory gout patients.
SEL-212 applies Selecta's Synthetic Vaccine Particle (SVP) products for immune tolerance to pegsiticase. The product is designed to durably and specifically prevent undesired immune responses that can appear after multiple dosages of uricase.
Currently two versions of uricases are approved for use in the United States. Both products induce anti-drug antibodies in more than 50% of patients that can reduce efficacy and cause severe allergic reactions.
About 3SBio Inc.
3SBio is a fully integrated, profitable biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products primarily in China. Since its founding in 1993, 3SBio's R&D efforts have resulted in four NDAs for biological medicines, including TPIAO, the first rhTPO approved worldwide. Pipeline candidates include Uricase PEG-20, a modified pegylated recombinant uricase from Candida utilis for the treatment of refractory gout and tumor lysis syndrome which has completed US Phase 1 trials; NuPIAO, a long-lasting rhEPO for anemia associated with renal failure or chemotherapy and peri-operative blood cell mobilization which has received SFDA approval to initiate clinical trials; and SSS07, an anti-TNF monoclonal antibody for treating rheumatoid arthritis, psoriasis, and potentially other inflammatory diseases. A new state-of-the-art mammalian biological manufacturing facility in Shenyang is the first and only rhEPO facility in China that conforms to both Chinese and European pharmacopeia standards. Planning is underway to develop monoclonal antibody manufacturing capabilities. 3SBio is China's leading specialist in nephrology and oncology supportive care with 580 sales professionals covering over 3,000 hospitals in key cities supported by a nationwide network of 120 distributors and logistics providers. EPIAO has been the top selling rhEPO product in China since 2002 with a market share over 40%. Please see www.3sbio.com for additional information.
About Selecta Biosciences
Selecta Biosciences, Inc. is a clinical-stage biotechnology company developing novel drugs that use immune modulating nanomedicines to generate targeted antigen-specific immune responses to prevent and treat disease. Selecta's proprietary Synthetic Vaccine Particle (SVP™) platform creates a novel paradigm in immunotherapeutics and vaccines, enabling completely new applications while offering the potential of improved efficacy and safety profiles.
Selecta's immunomodulatory SVPs can induce antigen-specific immune tolerance, enabling them to be applied in a variety of therapeutic areas with large unmet medical need. The company is focused on three key near-term applications: inhibition of immunogenicity for biologic therapies, treatment of allergies, and treatment of autoimmune diseases. Immunogenicity adversely affects the safety and efficacy profile for many biological therapies, and has caused the termination of a number of promising biological therapies in clinical development. Selecta's SVP is a product engine that has the potential to unlock the full therapeutic value of biological therapies.
Through proprietary products and collaborations with leading pharmaceutical companies and research organizations, Selecta is building a pipeline of product candidates to address unmet medical needs in serious and chronic diseases. Selecta Biosciences, Inc. is based in Watertown, Massachusetts, USA. For more information, please visit www.selectabio.com.
Investor / Media Enquiries
Tan Bo
Tom Folinsbee


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Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Creutzfeldt - Jakob disease pathophysiology
Classic CJD is a human prion disease. It is a neurodegenerative disorder with characteristic clinical and diagnostic features. This disease is rapidly progressive and always fatal. Infection with this disease leads to death usually within 1 year of onset of illness. Creutzfeldt-Jakob (KROITS-felt YAH-kobe) disease is a degenerative brain disorder that leads to dementia and, ultimately, death. Symptoms of Creutzfeldt-Jakob disease (CJD) can resemble those of other dementia-like brain disorders, such as Alzheimer's. But Creutzfeldt-Jakob disease usually progresses much more rapidly. There are different types of CJD: variant (vCJD), sporadic (sCJD), familial (fCJD), iatrogenic. Symptoms of CJD are rapidly progressive dementia, leading to memory loss, personality changes, and hallucinations, anxiety, depression, paranoia, obsessive-compulsive symptoms, and psychosis. Various causes of CJD are: Transmission, Blood donor restrictions, Sperm donor restrictions. Diagnosis of CJD includes: Electroencephalography, Cerebrospinal fluid analysis for 14-3-3 protein, MRI of the brain.
Creutzfeldt - Jakob disease Statistics
These statistics are calculated extrapolations of various prevalence or incidence rates against the populations of country. The approximate number of patients encountered with Creutzfeldt - Jakob disease in Russia is 143.
Creutzfeldt - Jakob disease Treatment
Currently, there is no cure for Creutzfeldt-Jakob disease. Treatment is aimed at alleviating symptoms and making the patient as comfortable as possible. Drugs can help relieve pain if it occurs. The drugs clonazepam and sodium valproate may help relieve myoclonus or irregular, jerking movements.
Creutzfeldt - Jakob disease ongoing research
Some ongoing research studies on Creutzfeldt - Jakob disease in Russia are Role of zinc and copper ions in the pathogenetic mechanisms of Alzheimer's and Parkinson's diseases, Creutzfeldt-Jakob disease: a new view on an old problem (clinics, diagnosis, prognosis, treatment.

subset: commoncrawl


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You are looking at 1-1 of 1 chapters for:
- 8 Punctuation x
- 8.7.6 Units of Time and Money as Possessive Adjectives. x
Units of Time and Money as Possessive Adjectives
Cheryl Iverson
in AMA Manual of Style: A Guide for Authors and Editors (10th edition)
With units of time (minute, hour, day, month, year, etc) used as possessive adjectives, an 's is added. The same holds true for monetary terms:


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Domain names include one-page websites, e-mail accounts, and Google webmaster tools; added storage and intuitive site builders available
Customer Reviews
What You'll Get
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Promotional value expires Feb 27, 2013. Amount paid never expires. Limit 1 per person. Limit 1 per visit. Limit 1 code per GoDaddy.com account. Valid only for option purchased. Valid online only. Online registration required. Offer valid to U.S. and Canada residents only. Must be 18 or older. Gift cards, Paypal, Alipay and CCavenue may not be used to redeem offer. Goods sold by GoDaddy.com. Paid value will be applied to first purchase. Must be an existing GoDaddy.com customer or create a new customer account to redeem. Merchant is solely responsible to purchasers for the care and quality of the advertised goods and services.
About GoDaddy.com™
GoDaddy powers the world's largest cloud platform dedicated to small, independent ventures. With nearly 17 million customers worldwide and over 71 million domain names under management, GoDaddy is the place people come to name their idea, build a professional website, attract customers and manage their work. The company's mission is to give customers the tools, insights and the people to transform their ideas and personal initiative into success.


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Not sure if this is the right place to report it to (not an in game issue so probably this is not ticket-able).
I checked and I show zero warning points as well (just to be sure). Now my notifications have stopped working. I do not see the notification icon show up with a red callout as it did in the past when new posts were made to threads I subscribed. Nothing after Nov 10. I tried clearing cookies as well as from a different PC. Windows 8 as well as Win10. Same issue.


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It's that time of year when you walk outside and your car is covered by yellow dust. Also that time of year when you're outside for 30 seconds and you start sneezing (not fun, is it?)
Pollen negatively affects human health in a variety of ways. When the pollen count is high, many experience:
- Runny and/or stuffy nose
- Itchy eyes
- Sneezing
- Respiratory problems such as asthma.
These symptoms could be contributed to a pollen allergy, typically referred to as hay fever.
Weeds, grasses, trees, and some shrubs are the common culprits for pollen. Weeds have commonly been determined to be the most productive of pollen producers and are identified as the plant that causes the most allergies.
How does pollen cause my symptoms?
When pollen is inhaled through the nose and throat, the body experiences an immune response that results in hay fever, because it attaches to the cells and creates histamine. It is this releasing of histamine that causes the symptoms of pollen allergy.
How can I avoid pollen?
The most overlooked way to avoid pollen is a simple change of your home air filter. Air filters are proven to reduce many of the common airborne contaminants, such as pollen, from the air you breathe. In addition to changing your air filter on a regular basis, here are some other things you can do to avoid pollen this spring:
- Stay indoors, being sure to keep windows closed during high pollen counts
- Wash hair before going to bed at night to avoid sleeping in pollen that accumulated in the air during the day
- Make sure outdoor pets are bathed before coming inside. This can prohibit the distribution of pollen on furniture and carpets
- Consider the use of an air filter and possibly even an air purifier in your home for more protection from pollen and other contaminants such as dust mites and viruses
*Tips taken from ehow.com*
This spring, you don't have to let pollen get the best of you. By regularly replacing the air filters around the home and being more mindful of local pollen counts, you can find yourself winning the battle against pollen.


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|Mfg Part Number: KS83C206EQ
|Manufacturer: Samsung
|Description: Ic
ASAP Purchasing is leading supplier for Samsung obsolete computer hardware parts and networking components with fastest RFQ response time. Get Immediate Quote for Samsung part number KS83C206EQ Part Description Ic .. Send quote along with desired order quantity, targeted price and order-fulfillment date. Our sales team will contact you shortly with a response. We are open for business 7 days a week, 24 hours a day to assist with all parts requirements. If you have a Spreadsheet/BOM can be sent via email to email@example.com in an excel format.


text: Seller: goran0702 (3,909) 100%, Location: Riga, Ships to: Worldwide, Item: 371649000045 Seal-Ring signet pseudo heraldry image. XVII-XVIII century. Bronze alloy. Size 21,0 mm (11,0 USA) Weight 3,38 gr. Normal 0 false false false LV X-NONE X-NONE All items listed are genuine artifacts. 100% authentic. No fakes, nor copies, nor reproductions. Own a piece of ancient history! Bid now! Before bidding. Please see my feedback to check my prior performance and to see what other buyers have said about my auctions. Please take a close look at the picture. You will receive exactly what you see on the picture, nothing more, nothing less. Please feel free to contact me if you have any questions before you place your bid.Please view the pictures for your own estimation of the item. The item on the picture is the one you will receive. If you require any further details or scans of the item please contact with me and I will be happy to provide you with more comprehensive details where available. Payment I accept Paypal only. Please pay in 3 days time or contact me if you need more time. Shipping Your item will be shipped in 3 days (or sooner) after payment. You will also always be informed exactly when your item ships. The quicker you pay, the quicker your item is mailed. Shipping WORLDWIDE from Latvia, member of EU. I ship almost all my items using Standard Air Mail services. However, I will purchase a different shipping service for your item at your request. Shipping charges for international shipping depend on package weight : Items with package up to 001 – 100 gr. (0,00-0,22Lb) 6,00 USD 101 - 249 gr. (0,22-0,55 lb) 8,00 USD 250 - 499 gr. (0,55-1,1 lb) 14,00 USD 501 - 999 gr. ( 1,1-2,18 lb) 22,00 USD 1000 – 1999 gr. (2,18-2,41 lb) 40,00 USD Combined Shipping Combined shipping will depend on weight of the package and I will calculate it depends on actual shipping rates of Latvian Post Office. Please wait before paying and I will invoice next day or sooner. Multiple purchases one shipment one invoice saves you and me money. Feedback: If you are satisfied with your items and my service --I await you positive feedback and 5 star rating. I advise you to contact me first if you are not satisfied with my service!!I am free to contact!! You will receive your feedback after leaving feedback for me. Be sure to add me to your favorites list ! Thank's for looking & happy bidding! Material: Bronze


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Motivation to Exercise
Posted by Coach Kim Collins on July 20, 2012
I didn't want to do it! Although my mind and mood were telling me that I didn't want to exercise today- I knew I needed to. I tried to talk myself out of it, I even created excuses in my head. I mean it was raining out, who feels like exercising when it's raining out?
So, here are 3 things I did to motivate myself to get moving even on a rainy day:
I put on my shoes
I found a good movie (that would take my mind off the fact that I was exercising) to watch on Netflix
I stepped on the treadmill with my iPad and hit the start button!


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No Hugh Jackman at the Oscars? What are we supposed to do? Our own over-the-top Precious dance parodies?
Sadly, the prevailing rumor is that Hugh Jackman has turned down an offer to return as next year's Oscar host. So instead they're looking for two hosts, with opposite generational appeal, like Steve Martin and Tina Fey. That particular duo would be weird for many reasons, and while having multiple hosts usually also ends up being awkward (Hi, 2008 Emmys!), I say why not try it, if the casting's right. Like Zac Efron and... I dunno, Wilford Brimley or somebody.
Simon Cowell told Gordon Ramsay to get plastic surgery to repair his crease-y face, and he actually did it. And though he doesn't look all that different post-surgery, Gordon Ramsay should know that only donkeys and donuts let Simon Cowell boss their faces around.
Cougartown is going to Friends it up even more in an upcoming episode, in which Lisa Kudrow will guest as Courteney Cox's mean dermatologist. You know who else that show needs from that other show? Selleck!
While watching last week's Yankee games, I noticed a horribly distasteful DirecTV commercial running a lot, in which current David Spade is edited into Tommy Boy's "Fat Guy in a Little Coat" scene to tell the singing (and dead) Chris Farley about the merits of satellite television. And while I'm sure you found it to be in poor taste as well, the good news is we were all apparently wrong. It's really a beautiful and appropriate tribute to a beloved fallen star. David Spade's publicist told a misogynistic website so. That is such a relief!
Oh, and speaking of awful things in poor taste, after Microsoft finally actually watched an episode of The Family Guy, they pulled their sponsorship. If only they'd asked us months ago and saved everybody the trouble.
For more from Television Without Pity:


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Grunge flyers/posters Ready for print 300 dpi cmyk, rgb Sizes: 4×6 Include bleeds, trims and guidelines Quick Photo Replacement Easy to modify
Used font: Arial
Instruction included!
NOTE : The photos used in the preview are not included. They're only for illustration purpose. You can quickly replace the default image with the photo you want!


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This is so much fun: If you enter your height and weight into the amazing gizmo at the BBC's website, you can find out how you measure up in comparison to Olympic athletes. Here on staff at the HQ, we've got a hammer-thrower, a ping-pong champ, a boxer, a diver, and a 100M runner.
[BBC News]


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Tommy Lee Gossip
Tommy Lee gossip, latest news, photos, and video.
Brad Pitt: back to work
W Blanco /BACKGRID
It's been weeks, maybe more, since we've seen Brad Pitt. Here he is in Baker, California on the set of James Gray's Ad Astra, a film about space travel. Which I think explains what he's wearing, if there's any CGI involved. Full Story
Star-crossed Skank Love
Two skanky scabs who can't stay apart – Tommy Lee has revealed exclusively to Rolling Stone that he and Pamela Anderson are back together. She's moved into the house with their sons and they're trying to make it work… again. Full Story
Meeting Motley Crue
Had no idea it would be like what it was. All they said was that Motley Crue was making an announcement – the inaugural Crue Fest this summer and a new album – and we were invited to the press conference and interviews with the band afterwards. Full Story
Pam: Family Day and Fraud
Pam and Tommy took their boys out for a movie yesterday in Malibu, apparently narrowly avoiding a run-in with Rick Salomon who has filed fraud claims of his own against Pam (she did the same) as they both move to annul their 2 month marriage. Annulment. Not divorce. Curious. You will note – Rick is considerably wealthier than Pam. Full Story
Trash Not Spawning…
Breathe easy. Xenu is not torturing us with any more Pam progeny. In an interview tonight with E! Canada's bimbo denies the recent reports: No more kids. No more kids. Of her pending divorce from Rick Salomon, she goes on to say: "I wish him the best. It"s a can of worms. Big, fat juicy worms, but worms. Full Story
Pam's Proud Moment
Pam's romantic resumé is all class. Her two ex-husbands, seated a few tables apart, apparently could not stop taunting each other. Needless to say, because all white trash confrontations end in a scrap, they ended up coming to blows, with Kid decking Tommy hard before security stepped in to drag them out. Full Story
Old School Runway
Galliano for Dior Haute Couture Fall Winter 07/08 – always over the top, always exquisite, always completely impractical…but it's couture, right? Why be sensible if you can afford a 50 thousand dollar dress? This year however marked the House of Dior's 60th anniversary and on the heels of the sudden death of Galliano's stalwart best friend Steven Robinson, anticipation for the show was particularly heightened with many wondering if John could possibly pull it off without his right hand. Full Story
No Wonder
Coincidence or conspiracy? Janice Min declares a ban on Paris Hilton, People Magazine whips out its new cover: an exclusive with Hollywood Ebola complete with photo shoot and interview. So now People Magazine is the prophet for the new Paris Hilton? If you are a subscriber to the magazine, you probably aren't too impressed, are you? And how changed can one person be if the first priority post-prison is to fix her weave and pose for a photo? Bitch… please. Full Story
Sympathy Skank – CAUTION LEWD!
"Stable" condition? Oh please. So Hollywood Ebola has ADD and is claustrophobic. The way they're talking it's like none of the other inmates have suffered any worse. But still it warrants VIP treatment and coddling, conveniently from some power player who may or may not have received financial favours from her grandfather… And still the sympathy train continues: Poor Paris is deteriorating, poor Paris is on the verge of a nervous breakdown…who the hell is buying this sh-t??? How about Poor Paris just needs a double bump? A line of coke and a c*ck come next week, when she gets out, and all will be right again. Full Story
Vanity Fair: The Africa Covers
"These are incredible people of our time, involved in this effort to make Africa better, to get Africa self-sufficient, and to try to get rid of aids on the continent." Shot by Annie Leibovitz on 20 different covers – 21 major names posing for Africa like a "visual chain letter" promoting awareness and discussion about the future of Africa. Full Story
Edward Norton: Is He Poor?
I suppose I can understand the decision on the part of Marvel Studios – Edward Norton plays dark and conflicted and morose and depressed better than almost anyone else. And what better adjectives to describe The Hulk? But according to early reports, the sequel to Ang Lee's 2003 box office disaster will be "less serious" with a much more comic-book feel… like smash, wham, bam, no relevant dialogue, just visual hypnosis. Full Story


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Picture Perfect Digital Designs
5.5 x 8.5 Invite & Envelope
Hot tamales! It's an awesome time of year to eat some authentic ethnic food! Why not have a Mexican fiesta for your next dinner party? Especially when Polka Dot designs offers these fiesta invitations by Picture Perfect Designs. These cute cards are sure to convey to invitees that the fiesta won't be mild, but hot and spicy! These cards depict a pair of hot chili peppers in the background of the customizable text you can create for your fiesta. Include when you want to have the party, (probably best after a mid-day siesta) and what kind of food you will be serving. A fiesta should be nothing but the "besta", and no fiesta will be complete without these festive invites. Break out the chips and salsa, play some mariachi music, and get in the mood to write out some of these invitations today. It will be a party your guests won't want to miss.


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Samsung Propel Pro SGH-i627
Info Photos News Forum 5 Reviews
Average Ratings
First Day With Propel Pro
I was a crackberry user looking for a little change. I went from the Pearl to the Samsung Eternity. After 3 weeks with the Eternity I called it quits. I needed something with real keys. This is my first WinMo phone. So far, so good.
- Easy to use
- Home screen has everything you need for everyday use
- Keyboard is surprisingly easy to use
- "joystick" makes for easy navigation
- great camera
- External microSD slot(hated the internal slot of the Eternity)
- Mobi TV
- Wi-fi
- The finish makes it hard to see the screen in daylight
- it's a slider phone(not a big fan of sliders)
- missing 3.5mm jack
- $30 data plan(Eternity was only $15)
- Insurance is $20 more(standard for smart phones vs. regular phones)
Overall I am very happy with this phone and would recommend this phone to anyone who is looking for a user friendly smart phone.
Had phone over 30 days, One major problem
If you like Windows Mobile this phone is great.
The slide is sturdy
The keyboard is easy to use
Everything from the rings to voice volume is nice and loud
Screen is nice
Even the camera is good!
The soft keys stick out from the face of the phone and are sensitive.
This is my one major issue with this phone. On incoming calls the soft answer key is active no matter what mode you are in. When I remove the phone from the holster or slide it out of my pocket I always hit the soft answer key and the phone answers before I am ready. I contacted Samsung tech support and they said that this is the way it is. I now have the phone upside down in the holster so the buttons are at the top and have to be very careful when ever I take it out to answer a call. I still hit the key every once in a while! Very frustrating!
Besides that it is a great.
I gave the phone a 3 because I think having the soft keys stick out is a major design flaw!
Excellent Business Phone
I upgraded to the Propel Pro from a Blackjack II (WM 6.1) a couple weeks ago (three days after the device was released at AT&T). I have been a Windows Mobile Standard user for a few years have tried Mobile Pro and wasn't thrilled with it, particularly the way it handles mail. I have tried touch screen devices and didn't really like those either. And I'm not a fan of Blackberry devices. All these things considered, I was drawn to the Propel Pro.
At first I was hesitant about this device, since on paper it is heavier than others and it didn't offer much improvement over my Blackjack II. However, when I got it I was pleasantly surprised. The size and weight aren't an issue at all, and I am really enjoying the size of the screen and speed of the processor. And the way it processes my email is great. I have three email accounts on the device, with a long list of rules that put my mail into different folders. I sync with Exchange with no problems at all, and the device itself is pretty darn classy looking.
The media applications work as well as I need them to. I don't listen to a lot of music on my phone, but I certainly could, and the fact that the Propel Pro can accommodate a 16GB micro SD card (although some places claim 32GB) means that I can carry around a bunch of albums. The speakers are decent for a cell phone, but not super. Get yourself some headphones and the problem is solved.
My only real complaint about this phone is the battery life. When compared to the Blackjack II, the Propel Pro gets about 75% of the battery longevity, but I have chargers at home, at work, and the car, so no biggie.
I have read that others complain about the fact that the phone is a fingerprint magnet, or that the screen is hard to read in sunlight, and those are valid, but if these are not major stressers in your life, this is a great device.


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Published at Saturday, July 27th, 2019 - 03:54:04 AM. Wedding Venue. By Adal Keller.
Size is an issue. Whoever says size doesn't matter is wrong. If you have 60 people attended your wedding reception, you want to find a wedding venue that accommodates around 60-80 people. Why get a great venue that holds 150 people then not even half fill it, your wedding guests will be rattling around inside, and all atmosphere will be lost. Assuming you're planning a DJ or Band for the evening's entertainment for your wedding guests, then ensure they have enough space to set up their equipment, consider where you can visualise the wedding party dancing and see if there is room for the entertainment to set up.
A memorable and mesmerising reception is the result of sensible, responsive and careful planning of the wedding day. All it takes is to be comfortable, have patience and choose the finest and the most amazing wedding venue in order to arrange the complete wedding reception, dance, lunch, dinner and wedding games in an impeccable manner. However, choosing a venue requires lots of knowledge; this is why it is crucial task. Indeed, the complete wedding reception program is dependent upon the choice of the wedding venue. In fact, other wedding reception arrangements are also dependent upon the venue and its location. Therefore, deciding an ideal venue is the very first step of the wedding planning process.
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For the entering class of 2016, admission to Ivy League universities will be more competitive than ever. Top schools will likely reject 80-90% of all candidates, including many with perfect grade point averages and test scores. How do they decide who gets in? Many applicants would kill to know the admissions "secret," the competitive edge that can help them gain acceptance.
In such a talented pool of applicants, exceptional writing (in a persuasive, well-conceived essay), augmented by credible third-party reference letters, often makes the difference between acceptance and rejection. Surprisingly, few applicants realize the importance of these factors in the evaluation process. Rather than write a compellling personal statement, they simply rehash their achievements in a boring, laundry-list style, leaving the impression that they are dull academic machines. Others don't know what the committee is seeking, so they decide to "play it safe" by submitting a generic essay that could have been written by anyone. Sadly, these half-hearted efforts rarely open the coveted Ivy League doors.
Fortunately, we can help. IvyLeagueAdmission.com was created by a team of Ivy League graduates who have served on more than seventy admission committees for law school, medical school, business school, and undergraduate programs. Through this experience, we have acquired a thorough understanding of the selection process and the challenges that candidates face to compete in such an exceptional pool of applicants.
Our mission is to offer specific guidance to medical school, business school, law school, and undergraduate candidates on all aspects of the admissions process. We understand the factors that influence the critical acceptance/rejection decision, including the importance of the admissions essays and reference letters. We also know the most common (and preventable) mistakes that will ruin an applicant's chances.
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11th Disaster Relief Fund - From the Heart
Brothers Truck Parts Hosts a Benefit Show for the September 11th Disaster Relief Fund
With the terrible events of 9/11 still extremely fresh in the minds of all Americans, this past November the folks from Brothers Chevy/GMC parts took it upon themselves to put together and host a benefit car/truck show in Chino Hills, California. And as was done by countless businesses, clubs, and individuals across the country, these fine folks stepped up to the plate to collect funds for the American Red Cross September 11th Disaster Relief Fund.
Anyone who's ever been involved in the planning and execution of an undertaking as complex as putting together a show of this kind knows that it's not an easy chore. And to do so with the express intention of donating the proceeds to a worthy cause is admirable. Though we couldn't attend all the benefit events held around the country, we at CLASSIC TRUCKS did want to show our support by covering an event which we're sure mirrored many throughout the land.
As most are aware, Brothers annually hosts one of the best Chevy/GMC truck shows in the West, so it was a pleasant change for all those involved to produce a show open to all years and makes of both cars and trucks. And judging by the number and enthusiasm of those gathered on the grounds of Ayala High School for the show, everyone agreed.
In addition of a huge contingent of some of SoCal's coolest cars 'n' trucks there were live performances by bands like the Hot Rod Trio and Interstate (a bitchin' alternative rock band made up of some Ayala H.S. seniors) playing throughout the day. There were also numerous auto and truck-based vendors, non-automotive vendors, and a plethora of great food and drink, as well. And as if that wasn't enough to guaranty a good time, there was even a gaggle of Lakers Cheerleaders circling the grounds (much the delight of every red-blooded male in attendance) saying hello and posing for snapshots.
So, enjoy the event photos as much as we enjoyed takin' 'em, and join with us in thanking the folks from Brothers Truck Parts for a great benefit show and those around the country who've done the same out of the kindness of their hearts. God bless them all, and God bless America.


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Fall is in the air. This is the perfect place, Outdoor Wednesday, to see some of the best fall colors nature has provided. Please join me with Susan at http:// asoutherndaydreamer.blogspot.com.
Tuesday, October 5, 2010
Outdoor Wednesday
Posted by LV at 6:00 PM
Labels: outdoor Wed.
28 comments:
- teresa said...
Isn't fall wonderful? Those trees are so gorgeous.
- October 5, 2010 at 6:42 PM
- High Heeled Life said...
Gorgeous!!! Autumn is my fav season!! HHL
- October 5, 2010 at 7:01 PM
- farmlady said...
These photos remind me of why I love Autumn.
- October 5, 2010 at 7:34 PM
- ♥ Calamity Anne ♥ said...
Gorgeous colors...and great photos!!! In my part of Texas we're still a long way off from getting any colors!
- October 5, 2010 at 7:37 PM
- Janis said...
Beautiful..don't you just love fall!!
- October 5, 2010 at 8:27 PM
- Betsy from Tennessee said...
Beautiful Fall colors, LV.... That is a perfect picture for Outdoor Wednesday.
- October 5, 2010 at 8:44 PM
- Genie said...
Well, from the looks of this picture, fall is knocking on your door, too. It is pretty chilly here, but I am ready. Bring it on. No more hot weather for me for a while.
- October 5, 2010 at 8:50 PM
- Marites said...
gorgeous fall colors! the photo looks like a beautiful painting!
- October 5, 2010 at 8:55 PM
- JEANNE said...
Your fall photos are so pretty. Our fall is late but will be here soon. To night we will have frost and that will bring out the color. I love fall very much.
Hugs, Jeanne
- October 5, 2010 at 9:28 PM
- Happy Cottage Quilter said...
Love the fall colors. Great pictures.
- October 5, 2010 at 9:50 PM
- George said...
It's good to see the beginnings of autumn colors. This is a great October picture for 'Outdoor Wednesday'.
- October 5, 2010 at 9:55 PM
- Light and Voices said...
I can almost smell the clean air. I can hear the crunch of fall leaves on the ground. Love fall, don't you?
Joyce M
- October 6, 2010 at 12:14 AM
- Red Nomad OZ said...
Over here on the other side of the world, we're gearing up for summer! So it's nice to get a reminder of what's in store in 6 months or so ...
Happy travels!
- October 6, 2010 at 2:33 AM
- Jan said...
Beautiful pics, LV.
Love, Jan
- October 6, 2010 at 4:36 AM
- Donnie said...
Lovely Fall colors. Not as many trees are changing in my area yet but the news keeps saying we'll have great color.
- October 6, 2010 at 9:11 AM
- Sherry said...
Don't you love fall? Beautiful photos.
- October 6, 2010 at 9:59 AM
- LindyLouMac said...
I am blog hopping from Italy for Outdoor Wednesday and am delighted to meet you. Thanks for calling by News From Italy and commenting, I have now answered there.
Thankyou for sharing your glorious fall for me to enjoy virtually. I just love being able to travel the world via the blogsphere.
- October 6, 2010 at 12:23 PM
- Nora Johnson said...
Gorgeous colours and a gorgeous blog!
Have a lovely weekend,
XOXO Lola & Nora:)
- October 6, 2010 at 12:36 PM
- EG Wow said...
It's very beautiful there!
- October 6, 2010 at 1:39 PM
- email@example.com said...
Just want to lay under those trees with a blanket and a good book! Beautiful shots.
Tks for stopping by!
- October 6, 2010 at 1:59 PM
- Linda said...
It looks like Fall is beautiful where you live!
- October 6, 2010 at 2:43 PM
- Rita said...
LV, thanks for stopping by to see my posting of the spider girl and her surprised friend.
Love your blog and your slant on life. My 85 yr old mother is living by your same principle and I hope that I will live long enough to do the same at your age.
- October 6, 2010 at 3:16 PM
- JEANNE said...
That is funny LV. Great minds... My friends sends me a lot of good stuff about animals. She knows I love them. The black deer is just so odd. Someone captured some great photos.
Hope you had a great day.
Hugs, Jeanne
- October 6, 2010 at 4:21 PM
- HollyC said...
Beautiful Fall trees! It's my favorite time of year. Thanks for sharing.
- October 6, 2010 at 7:35 PM
- Vintagesouthernlife said...
Gorgeous fall colors. My favorite time of the year.
- October 6, 2010 at 10:25 PM
- Rose said...
fall is bright and beautiful. thanks for the pictures rose
- October 7, 2010 at 12:11 AM
- Incipient Wings said...
this is beautiful...we're still a bit warm here, but I love looking at the amazing photos.
- October 7, 2010 at 2:55 AM
- daylily777 said...
Beautiful Fall color ! Great Pic !
- October 10, 2010 at 7:15 AM


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Maximises protection against cuts, scrapes, and rashes.
Keeps your body dry and muscles warm, for maximum performance.


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Top SongsSee All
heavy metal (feat. Rahzel)Bring Me The Horizon 2019
Cold Blooded (feat. Rahzel the Godfather of Noize & Roy Hargrove)Common 2000
Mojo (feat. Rahzel & Dan the Automator)Peeping Tom 2006
AlbumsSee All
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About Rahzel
Probably best known in the semi-mainstream world as a member of the Roots, Rahzel is an MC that specializes in the "fifth element" of hip-hop culture -- beatboxing (which comes after graffiti spraying, DJing, MCing, and breakdancing). He actively discourages classification of his sound, attempting to remain on the eclectic edge of the commercial music. According to the artist, his influences include Biz Markie, Doug E Fresh, Buffy of the Fat Boys, Bobby McFerrin, and Al Jarreau. His goal is to gain respect for beatboxing as a true art form on its own merits. Growing up, Rahzel looked up to his cousin Rahim of the Furious Five, and went to Grandmaster Flash's shows regularly. He later became a roadie for the Ultramagnetic MCs. Rahzel has in fact mastered the art of beatboxing, able to recreate full songs, with accompaniment by himself without instrumentation, able to sing a chorus and provide a backing beat simultaneously, able to invoke impressions of singers and rappers on a whim. Any fan of hip-hop should definitely invest in his Make the Music 2000 album. ~ Adam Greenberg
Similar ArtistsSee All


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May 27, 2009
Wednesday Type: Things made from things
- "Clock Clock" turns 24 analog clocks into one big "digital" display.
- This Rubik's Cube stamp promises to print the entire alphabet.
- Thomas Broome builds worlds out of subtle lettering. [Via]
- In a similar vein, H5's video for Alex Gopher constructs a city of words (screenshots).
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Blake Lively stars as Serena van der Woodsen.
Over the last couple years, the actress has become one of the most sought-after young stars in Tinseltown. In the summer of 2006, Lively starred in Universal's summer comedy "Accepted." Years before that, Blake made her big-screen debut in "The Sisterhood of the Traveling Pants," for which she earned a "Breakthrough Performance" nomination at the "2005 Teen Choice Awards."
She was also honored at the December 2006 Hollywood Life Breakthrough Awards. Lively graduated from high school in the spring of 2006 and lives in Los Angeles.


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Nearest Town: CataldoSite Size: 3.6 road miles
Highlights: Raptors, Shorebirds, Songbirds, Upland Birds, Waterbirds, Waterfowl
Access: Year-round. Access free of charge.
Directions: I-90 Exit #39 (Cataldo Mission); N on Dredge Rd 1.3 mi; L (W) on E Canyon Rd for 0.2 mi; R (N) on Hayden Ck Rd for 0.1 mi; L (W) onto Hayden Loop for 0.7 mi; rd meets Canyon Rd again; W on Canyon Rd; R (N) on Hardy Loop Rd 1 mi loop back to Canyon Rd; W on Canyon Rd 0.7 mi; S onto River Rd and cross over I-90, continue straight S on Tamarack
Ridge Rd 1.8 mi to intersection with River Rd; R (N) on River Rd 1.5 mi; backtrack to Coeur d'Alene River; W on S River Rd 2.5 mi to town of Rose Lake and ID 3.
Description: Please respect private property and bird from the road only. Near Dredge Rd look for Pied-billed Grebe, Wood Duck, American Wigeon, and Ruddy Duck. Tundra Swan and Canada Goose feed in this area in the spring. At the west end of Hayden Loop Rd, bird the ponds near the intersection with Canyon Rd. During spring and summer, look for blackbirds, Wood Duck, Hooded Merganser, Sora, Belted Kingfisher, and House Wren. Along Hardy Loop Rd look for migrating shorebirds such as Semipalmated Plover, Solitary and Spotted Sandpipers, Marbled Godwit, and Long-billed Dowitcher.
More Information: Kootenai County (208) 446-1000North Idaho Tourism Alliance (208) 263-1413
General Services:
Handicapped Services:What do these icons mean?
Select a species from the list to view other sites on the Idaho Birding Trail Sites this species may be observed.


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|EPM Scientific
US-NJ, Principal Biostatistician for a rapidly growing independent CRO 452431257283-MZ
|Principal Biostatistician
Location: New Jersey
Salary: $150k - $165k + Excellent benefits
A rapidly growing CRO is looking to expand its Biostatistics department. This firm is looking for a Principal Biostatistician to help build their Biostatistics department. Due to a significant investment this intercontinental CRO has plans to expand North America offices in Toronto and New Jersey.
This Principal Biostatistician will have a leadership role within the company and a chance to quickly progress through the company. This Senior Biostatistician will have an opportunity to make a large and immediate impact in the company.
The responsibilities of the Principal Biostatistician include:
Please visit our website at www.epmscientific.com


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(Aspidites ramsayi)
Growing to lengths of 3 metres, the Woma Python has an orange head and a light tan coloured body with darker bands.
The Woma Python inhabits South Western Queensland, Central Australia and parts of Western Australia. They will normally be seen residing in grasslands, shrubland and woodlands. They often take shelter in animal burrows where they will create a depression in the sand in which to shelter.
Primarily a reptile and mammal eater, the Woma Python on the left is hunting in a rock ledge for lizards or snakes. The Woma Python eats many species of Australia's most venomous snakes and is actually immune to venomous snake bites.
Australia Zoo has always had a great reputation for breeding endangered reptiles and once again we have had the good fortune to have one of Australia's most endangered species of python lay eggs and not just one snake but two. In 2004 we had our first taste of success in breeding the elusive Woma python when we hatched out one snake, in 2005 we had no eggs but in 2006 the formula must have been right because not only did we get 11 eggs from one snake we also got a second clutch of eggs from another female. Steve and Terri are committed to saving this species of snake they have even purchased huge tracts of land on the Brigalow Belt in central Queensland which is prime woma habitat. Hopefully with the Zoo's breeding efforts along with the protected habitat that has been set up hopefully we can save this wonderful and unique species of python.
The Brigalow form of Woma Python is in a lot of trouble! Land clearing and burning are the two major factors that are threatening the numbers of this snake in the wild. Australia Zoo is now the only facility in Australia to hold this form and we are extremely determined to breed and later release these snakes back into protected habitats. It would be absolutely devastating to lose this snake forever.


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IBM scales down PureApplication cloudy boxes
Fewer nodes and less storage, and presumably at a lower price
If you are looking for a low-end pre-configured, automated, application-ready cloud in a box but you don't need a big behemoth of a machine, then IBM finally has a configuration of its PureApplication systems that might be appealing to you.
Everybody wants to peddle pre-configured, automated, application-ready systems. At Oracle these are Exa boxes and, if you want to be generous, Sparc SuperClusters. At Hewlett-Packard they are CloudSystems. At Dell they were vStarts and now they are Active System 800s. And at Big Blue, they are PureSystems.
None of these are appropriately named, of course. They are trying to be Application Systems, of course, and the only problem is that IBM already took that name in 1988 with its venerable Application System/400, a preconfigured app box with an integrated relational database that eventually had 275,000 customers and generated well over $5bn in revenues a year at its peak.
It is not entirely clear what makes any IBM system "pure," that part of the naming convention was never explained, as if things didn't have to make sense. I don't think IBM's top brass get it, either.
The IBM PureApplication platform cloud
The System/360 was so named because it spanned a range from small to large systems and ran various operating systems and types of workloads, a 360 degree view of everything in your data center. (In theory, at least.) Good names are supposed to mean something, and it is not simply as matter of people not making sense anymore and they did in the past.
Netflix tells you exactly what it does, Google tells you exactly how much data it covers, and so on. I don't understand what PureSystems, the raw infrastructure cloud setup, means, and I don't know what PureApplication, which is akin to an AS/400 as reconstituted from x86 servers and integrated switches and storage to run Windows and Linux applications, means. (I guess everyone else is selling impure systems to Big Blue's way of thinking, er, marketing.)
I do understand that Flex System, the underlying hardware chassis for the Pure boxes, was meant to convey that the machine was integrated and flexible at the same time, allowing multiple kinds and sizes of server nodes and switching to be slid in.
So much for the philosophy. In a tersely worded announcement this week, IBM is offering two new configurations of the PureApplication W1500 system that was launched in April 2012. The original PureApplication W1500 machines, which started shipping at the end of July last year, were pretty heavily configured:
- W1500-96: 96 cores, 1.5TB of main memory, 6.4TB of solid state storage, 48TB of hard disk storage
- W1500-192: 192 cores, 3.0TB of memory, 6.4TB of SSD, 48TB of disk storage
- W1500-384: 384 cores, 6.1TB of memory, 6.4TB of SSD, 48TB of disk storage
- W1500-608: 608 cores, 9.7TB of memory, 6.4TB of SSD, 48TB of disk storage
It is hard to see what kind of value these PureApplication machines offer compared to alternatives, since IBM has not published pricing for them.
What IBM does say is that its DB2 database and WebSphere application server are pre-installed on these clusters, which run Red Hat Enterprise Linux, and its "patterns of expertise" automation for installing software can be used to automagically deploy hundreds of other systems and application software packages on the cluster.
With this week's announcement, IBM is offering two more smaller PureApplication configurations:
- W1500-32: 32 cores, 512GB of main memory, 2.4TB of solid state storage, 24TB of hard disk storage
- W1500-64: 64 cores, 1TB of memory, 2.4TB of SSD, 24TB of disk storage
Say what you will about Oracle, but the system configuration and list prices are out there. You know where to start on the bargaining. ®
Sponsored: Detecting cyber attacks as a small to medium business


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Opening Hours
|High season:
23 March - 31 Oktober
|Low season:
1 November – 22 March
|Monday - Friday
|9.00 - 16.30
|Monday - Friday
|9.00 - 16.30
|Saturday - Sunday
and public holidays
|9.00 - 16.30
|Saturday - Sunday
and public holidays
|11.00 - 13.00
Showroom and shop
In our showroom and shop you will find a wide range of authentic Delftware, everything entirely hand-painted. Our prices are factory prices. So a visit is not only a free guided but the opportunity to purchase authentic Delft for attractive prices as well. Items can be mailed all over the world.
Guided Tours
Our pottery can be visited by means of a personal guided tour. The tour is free of charge and starts every 10 minutes. A professional guide will show you around the pottery and will explain everything on how Delftware is produced. Our guides speak Dutch, English, Spanish, French, German, Italian and Swedish.
Travelling by car and parking
Highway A13 - Den Haag – Rotterdam
→ exit Delft Noord →direction Delft →follow signs "DELFT POTTERY de Delftse Pauw GPS/navigation: zipcode/postal code 2289 BD – Delftweg 133, Rijswijk (ZH) – Delftweg 133. Free parking
Travelling by public transport
Tram no. 1 or no. 19 → stop "Brasserskade"
You can follow the signs or take the route as indicated on the map in the slider below.


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OCEAN CITY – Ocean City will be garnering the opinions and thoughts of local residents, voters and property owners through the town's participation this year in a National Citizen Survey.
Kathy Mathias, assistant to the City Manager, came before the Mayor and Council Tuesday to update them on the progress of the survey that they approved earlier this year.
According to Mathias, the surveys were initially to be sent out to 1200 people.
"We ran into some issues because of property owners not living in the 21842 zip code," Mathias said.
As a result of some property owners not living in town year-round, two categories have been created; year round and property owners. About 3,000 surveys will now be sent out to property owners and year-round residents at random.
Mathias explained that the five-page long national survey will be customized for Ocean City and will also include a cover letter and the mayor's signature.
Because the survey is a national survey, a few changes needed to be made to fit Ocean City. For example, questions regarding subways and railways were not pertinent to the town.
Mathias explained that the survey would include a variety of questions, including three policy questions and one open-ended question. Four policy questions and two open-ended questions were presented to the City Council at Tuesday's work session for review.
The four potential policy questions touched on five-story building limitations; the amount of street space dedicated to vehicles as opposed to bikers and alternative forms of transportation; the Mayor and Council's support of the tourism industry; and the tax differential.
After reviewing the four potential questions, the council chose the first three questions. It was agreed the tax differential would hopefully be well underway before the surveys were sent out, making it not as pertinent.
While the policy questions provide a support/oppose scale for answering, the open-ended questions provide people a chance to give more elaborate thoughts and opinions.
The open-ended question chosen at the meeting was, "What do you think is the single biggest issue facing Ocean City over the next several years?" This question was chosen over, "Name any services that the town provides that could be improved."
Mathias explained that the answers provided in the open-ended questions would be collected and compiled into a list for the council to review.
The survey results should be returned by Thanksgiving.


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Low and behold I do not have a tutorial on something so basic that should have been created for the kids that come to Dragoart.com. I can't believe I never made a lesson on "how to draw a teddy bear for kids", step by step. How could I forget to do something so basic when it is kids that buy and snuggle with teddy bears? I myself used to have a teddy bear, but after having it so long he eventually became broken and torn. I tried fixing him several times before I said good-bye to my dear friend that had been with me since I was three. Anyways, this is what he looked like, but not in such a pristine version. I do think that you will enjoy drawing a teddy bear for kids because he is such a cute little guy to draw. If you want to change this boy bear into a girl bear, all you have to do is add a cute pink ribbon around the neck. Thanks guys and I hope you enjoy this tutorial.
DragoArt members upload artwork and drawing tutorials! They are also allowed to leave comments on tutorials, profiles, etc. Many more features, as well; it's way better than just being a boring guest! Register Now!


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by an anonymous friend…
From Kol HaTor Ch. 2/ Part 2:2
The general duty of the two messiahs, Mashiach ben Yosef and Mashiach ben David, together throughout the generations, is defense and war against the three chiefs of impurity - Esau, Ishmael and the erev rav, the "mixed multitude." Mashiach ben Yosef's special duty is confronting Esau, the impurity of the left. That of Mashiach ben David is confronting Ishmael, the impurity on the right. And together they work against Esau and Ishmael, the ox and donkey of impurity.
The mating of Esau and Ishmael comes through Armelius, angelic prince of the erev rav, and it can destroy Israel and the whole world, Heaven help us! The main striving of the erev rav is to mate Esau and Ishmael and separate the two Messiahs, and our own main battle is to shatter and rout the power of the erev rav, the impurity of evil Armelius, from (klal) Israel.
The erev rav is our greatest enemy. It is what separates between the two Messiahs. Its impurity operates only via indirect deception. Hence, the war against the erev rav is the hardest and most bitter, and we must gird ourselves with our last strength toward this end. Whoever does not actively take part in the war against the erev rav automatically becomes a partner to its impurity, and whoever he is, he is better off not having been born. The main strength of the erev rav is in the gates of Jerusalem, especially at the entrance to the city on the western dividing line.
The erev rav is that part of the Jewish People intent on war against G-d and against the truth and credibility of His Torah. With them we face an uncompromising battle to the finish, and the Gra (the Vilna Gaon, zt"l) emphasized this in his call to holy war against them. When he says that whoever does not actively fight the erev rav becomes their partner and is better off never having been born, he means to warn against the distorted tolerance and groundless love which are the main impediments in this war. Rather, says the Gra, our task is to assist our Messiahs in their task, and the task of Mashiach ben Yosef is once more emphasized there:
(Chapter I:6): "The general purpose of Mashiach ben Yosef is in three things: uncovering the Torah's secrets, the ingathering of the exiles, and eradicating the spirit of impurity from the Land." Whoever does not take part in this, strengthens the hand of those who block the way to redemption "in haste," thereby bringing upon us tragedies, grief and destruction, Heaven help us! Whoever refuses to fight them sheds blood.
It thus emerges from the study of Mashiach ben Yosef, the Inaugural Messiah and Messiah of War: I. Already at Creation, G-d prepared the Messiah (in other words, two Messiahs), as our sages said (Pesikta Rabbati, 36): What is meant by "In Your light we see light" (Ps. 36:10)? Whatever light the Congregation of Israel sees is the light of the Messiah, as it says, "G-d saw that the light was good" (Gen. I:4).
This teaches that G-d foresaw the Messiah and his deeds before the world was created, and stored him away under His throne to be Messiah to his generation.
The Soton said, "Master of the Universe! To whom does the light stored under Your throne belong?" G-d responded, "To the one who in the future will counter and humiliate you." The Soton then said, "Master of the Universe! Show him to me! G-d replied, "Come and see him." Once he saw him, he was shocked, fell on his face and said, "This is surely the Messiah who is going to push me and all the angelic princes of the nations into Hell."
I brought the rest of this Midrash previously: At that moment the nations became excited and said, "Master of the Universe! Who is this into whose hands we shall fall? What is his name? What is his nature?" G-d replied, "He is the Messiah and his name is Ephraim, My righteous Messiah."
** NO ONE should mistakenly interpret the above as some type of license for violent action within klal Yisroel – it is NOT. As written in Kol HaTor, "he means to warn against distorted tolerance and groundless love". Though terms such as "war" and "battle" are used, hakol kol Yaakov, the power of Yaakov is in his voice. Prayer, and maybe protest and politics. Building and growing and refusing to accept the unacceptable. THIS is a spiritual and intellectual war and is fought with the neshama and moach (soul and intellect), and by mobilizing for good deeds and steadfast stances.


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A great 10 mile loop with a variety of terrain, including some great trails along the Charles River and the surrounding wetlands and views from the top of Noon Hill. Covers several sections of the Bay Circuit Trail system.
Go here for course trail map: http://trailanimals.com/wp-content/uploads/2014/06/Shattuck-Reservation-Map.pdfStart time for both races distances is 7:00 am. There will be a mandatory 6:45 am pre-race briefing. . Two choices: 50K or 40M. The course starts/finishes at Holt Pond parking lot on Noon Hill Road in Medfield, MA, winding through Noon Hill Reservation. A beautiful but challenging 10 mile circuit consisting of mostly single track trail with varied terrain. With a dirt road into the starting area, one road crossing, and very few house sightings during the run, you will truly feel like you're running in the wilderness, not in a suburb about 15 miles from Boston! This race is an oasis in a month that is a virtual desert with respect to trail race options in New England and is perfectly positioned for those training for a late summer or fall trail ultra. The number of runners will be limited to 100 for both races combined so act fast if you want to take part. A sizable portion of your entry fee will be donated to the Trustees of the Reservation, the not-for-profit organization that owns and maintains the reservation. The total contribution from all runners will be matched by a personal donation to the Trustees from the race director! THERE ARE NO REFUNDS, NO TRANSFERS AND NO RACE DAY REGISTRATION FOR THIS EVENT.


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Foundation / Corporation
Epilepsy Foundation
Grants and awards to USA, Canada, and International researchers with an advanced degree (i.e., MD, PhD, MS, or PharmD), for scientific research projects that may result in new treatments for people with epilepsy. To start the application process, applicants must submit a letter of intent. Funding is intended to accelerate therapies onto the market in a timeframe that will make a difference.
ETP provides new therapy commercialization grants (NTCG) to support later-stage development projects past proof of concept stages. For projects that are beyond the resources of the Epilepsy Foundation, applicants can also apply for an Epilepsy Innovation Seal of Excellence award (SEAL). The SEAL is not a grant program but an official housekeeping seal of approval that a team can use to generate further venture capital interest. The SEAL awards undergo the same application and review process as the NTCG.
Areas of interest for the Foundation include:
- Novel approaches to treatment.
- Platform technology to advance screening techniques that can be utilized by multiple laboratories, including utility of techniques for early proof-of-concept trials.
- Adaptation of treatment in development for another therapeutic area to assess utility for epilepsy (while maintaining patent protection).
These grants support the development of more effective therapies by serving as a catalyst for moving innovative therapies from the laboratory to the patient. Note that preference will be given to proposals that already have a commercial partner engaged to assist with development and to proposals that have committed or matched funding from the sponsoring institution, commercial partner or other third-party source. For the New Therapy Commercialization Grants, applicants must demonstrate background work beyond the proof of concept / basic science discovery stage.
The Foundation supports projects spanning diagnostics and devices to small molecules and biologics. For programs that seek to develop diagnostics and/or devices, projects must be in later stage feasibility testing or in the proof of value stage (i.e. there should be a minimal viable product (MVP) prototype with a product IFU (instructions for use) to be competitive. For programs that seek to develop potential drugs through small molecules and biologics, there must be at least one lead compound identified, which may be at the pre-IND (Investigational New Drug application) to be competitive for a New Therapy Commercialization Grant. Investigators of drugs are strongly advised to have their compounds screened, as appropriate, by the NINDS ETSP Program prior to applying.
Priorities Will Be Given To:
- Research programs that might not otherwise be funded through traditional sources.
- Projects that encourage collaboration among scientists and industry.
- Projects with full intellectual property (IP) rights (composition of matter) are preferred over method of use IP.
GrantWatch ID#: 180289
New Therapy Commercialization grants are up to $200,000 for a maximum of 2 years.
The Epilepsy Innovation Seal of Excellence Award comes with no award dollars but an official housekeeping seal of approval that can be used to generate further venture capital funds.
New Therapy Commercialization funding is for a period of up to two years.
Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.
Apply online:
Dr. Sonya Dumanis, Senior Director of Innovation
For help with electronic application process, please contact the help desk for proposalCENTRAL: email@example.com or 1-800-875-2562.
USA: Alabama; Alaska; Arizona; Arkansas; California; Colorado; Connecticut; Delaware; Florida; Georgia; Hawaii; Idaho; Illinois; Indiana; Iowa; Kansas; Kentucky; Louisiana; Maine; Maryland; Massachusetts; Michigan; Minnesota; Mississippi; Missouri; Montana; Nebraska; Nevada; New Hampshire; New Jersey; New Mexico; New York City; New York; North Carolina; North Dakota; Ohio; Oklahoma; Oregon; Pennsylvania; Rhode Island; South Carolina; South Dakota; Tennessee; Texas; Utah; Vermont; Virginia; Washington, DC; Washington; West Virginia; Wisconsin; Wyoming
USA Territories: American Samoa (USA) Guam (USA) Puerto Rico (USA) Virgin Islands (USA) Northern Mariana Islands (USA)
USA Compact Free Associations: The Federated States of Micronesia (USA) Marshall Islands (USA) Republic of Palau (USA)
Canada: Alberta British Columbia Manitoba New Brunswick Newfoundland and Labrador Northwest Territories Nova Scotia Nunavut Ontario Prince Edward Island Quebec Saskatchewan Yukon
International country outside of the USA, Israel and Canada.


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Classic sock height at 7 inches above the ankle.
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We've created a baseball sock that not only looks great but exceeds everything else on the market when it comes to durability, technology, and design. Using our FEEL360 technology, the Dodgers Twist Crew eliminates over 99% of bacteria, quickly adapts to body temperature, and is proven to be two times more durable. This MLB on field sock has a built in cushion at the ankle which provides additional padding and protection against grounders as well as targeted lateral compression and seamless toe closures.
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Smart BalanceTM
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You try to be good to your heart. But sometimes it's hard to know where to start.
It means taking that extra flight of stairs. It means cutting down on stress. And it means taking time to think about what you eat.
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Against astronomical odds, next year California may play a decisive role in the Presidential nominating process.
It's been important before.
In 1964 conservative Senator Barry Goldwater sealed the GOP nomination when he dispatched the Establishment candidate, New York Governor Nelson Rockefeller, here.
U.S. & World
News from around the country and around the globe
In 1972 Senator George McGovern clinched the Democratic nomination with his California win. But for nearly four decades, the Golden State has been a by-stander.
In 1996 , frustrated with California's continuing irrelevance—despite being home to the nation's largest delegate trove, the legislature moved the state's primary up from June to March.
Other states jumped the line ahead of California—including nine contests on early March's "Super Tuesday."
So, in 2007, with the backing of then-Governor Arnold Schwarzenegger, the 2008 Presidential Primary was pushed up to February. And the state found itself swamped in a Super Tuesday tsunami of two dozen state primaries.
The cost to the cash-strapped state? Somewhere around $100 million.
This year, fed up with California's inability to gain political clout and scratching for easy spending cuts to help plug the state's burgeoning budget hole, the legislature passed AB 30, which once again consolidated the state's presidential primary with the June state ballot.
The move will have little impact on Democrats.
The incumbent President, Barack Obama, is likely to be easily renominated. But the GOP race has been fluid—even if the media have already anointed former Mass. Governor Mitt Romney and current Texas Governor Rick Perry the only contenders in a two-man race.
If the GOP race remains competitive and--given the tenacity of various "message" candidates-- it likely will, might California finally have the opportunity to make a difference?
Well, there's an outside chance, but it's a chance.
In the spin room at the MSNBC/Politico Republican presidentail candidate debate in Simi Valley on Wednesday, the buzz centered around Florida as The Decider.
Odds are that a social conservative—once thought to be Congresswoman Michele Bachmann, now Perry—will take the Iowa caucuses and an "Establishment" Republican—say, Mitt Romney, (although Jon Huntsman fits the description, too) will win the New Hampshire primary. The rubber match could take place in South Carolina, which looks like Perry turf, or Florida, where many of the so-called "viable" candidates are fighting fiercely, but where Perry appears to be the favorite--today. (His Social Security "Ponzi scheme" riff not withstanding.)
A decisive win in Florida could shut down the GOP nomination fight; a muddled result could portend a long trek through the primary calendar—perhaps all the way to June.
Remember the early run-up to California's 1998 Democratic gubernatorial primary? The race was positioned by the media as a big-money, brutal battle between two multimillionaires, while the eventual winner, Gray Davis, languished in a money-strapped, distant third-place.
Early Election 2008 surveys showed former-NYC Mayor Rudy Giuliani riding high in the polls. Then there was the premature coronation of Hillary Clinton on the Democratic side.
"It's important to remember that the first contest is five months away and anything can happen," GOP strategist Mike Dennehy recently told the Associated Press. "We shouldn't write anyone off until the first votes are cast."
At least.
The reality is that California will never be irrelevant in the Presidential nominating process—not as long as it maintains its status as the ATM of American politics.
Let us know what you think. Comment below, send us your thoughts via Twitter @PropZero or add your comment to our Facebook page.


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Welcome to Payless Car Sales . Be sure to visit our virtual showroom of inventory available for purchase. There you will see detailed information about each vehicle, a picture gallery, as well as convenient ways to contact us for more information about that vehicle. We are located at 14255 South Western Avenue and are available by phone at 708-385-1012 . You can also get driving directions and hours of service from our user friendly website.
At Payless Car Sales we are proud of the quality used cars we sell and our dedication to serve the needs of our customers. This is reflected in the amount of repeat business we receive. Whether this is your first purchase with us or one of many that you've had, you can count on our dedicated sales staff to make it the best buying experience possible.
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