text:
The 3 Arena went wild as James Gallagher won the Bellator 217 main event against Steven Graham with a rear-naked choke in the first round.
💪🇮🇪😳@StrabanimalMMA is victorious in his return to the Bellator cage with a rear naked choke at #Bellator217.
Watch the main event in the 🇺🇸 at 9/8c on @ParamountNet & simulcast on @DAZN_USA. pic.twitter.com/NgYWT2AsgI
— Bellator MMA (@BellatorMMA) February 23, 2019
It was the perfect way to bounce back for Gallagher who lost his first professional fight last time out.
Plenty had noted the confident demeanour of the 22-year-old going into the ring and he was justified in that as he made light work of Graham.
James Gallagher, who is coming off his first pro loss, is walking to the cage now in Dublin with the confidence of a man who's currently on a 20 fight win streak. Curious to see how he looks in there.
— Ariel Helwani (@arielhelwani) February 23, 2019


text:
The Montalbano hills also produce excellent red wines, such as the Carmignano, the Chianti Montalbano, the Barco Reale DOC. The town is known as the "Città del Mobile" for the many small and medium sized industries specialized in furniture.
Quarrata, Province of Pistoia, Tuscany, Italy
Quarrata is the seat of the commune - previously in Tizzana - only since 1959
The town lies at the foot of the Montalbano hills, an area full of Etruscan settlements and fine medieval boroughs, used by the Medici in the Renaissance as their private hunting reserve, called the Barco reale, where beautiful villas were established, such as the Villa Magia near Quarrata.
Altitude: 48 mt a.s.l -- Population: ca. 23,000 inhabitants -- Zip/postal code: 51039 -- Phone Area Code: 0573 -- Patron Saint: Madonna della Cintola -- Frazioni & Localities: Barba, Buriano, Caserana, Casini, Catena, Ferruccia, Forrottoli, Lucciano, Montemagno, Montorio, Olmi, Santonuovo, Tizzana, Valenzatico, Vignole.
The name probably goes back to the time of the Roman occupation, when the land was divided into plots called "centuriae" of regular geometric forms (a plot of land was called "quadrata" in Latin). The frazione of Tizzana was an important fortified borough in the Middle Ages, thanks to its strategic position dominating the plain between Florence and Pistoia.
During the war between these two towns, Quarrata was finally conquered by Florence in 1306. The castle of Tizzana lost importance, and in the early 20th century the municipality seat was moved first to Vignole and then to Quarrata.
What to see
- the Villa Màgia, an ancient castle founded by Vinciguerra Panciatichi in the early 14th century and purchased in 1583 by Francesco I de' Medici who changed it into a country mansion to be used during hunting periods. The last heir finally in 1999 alienated the Villa to the Comune.
- the Barco Reale Mediceo, a game reserve established in 1626, and at the time all enclosed by a 50-km long wall in bid sandstone blocks in the Montalbano hills; presently only traces of about 30 kilometers of the walls can be seen. The area is of great naturalistic interest, also because the Medici took great care in protecting the forests where still a great variety of trees and shrubs are extant.
- Early September, a traditional fair on the occasion of the patron festivity.
- Marcia per la Giustizia, a pacifist march against oppression organised since 1994 every year
- Good Friday, once every 3 years, a costume procession re-enacting the Passion of Christ
Where to stay
Provinces of TuscanyArezzo | Firenze | Grosseto | Livorno | Lucca | Massa-Carrara | Pisa | Pistoia | Prato | Siena
Other Italian RegionsAbruzzo | Basilicata | Calabria | Campania | Emilia Romagna | Friuli Venezia Giulia | Latium | Liguria | Lombardy | Marche | Molise | Piedmont | Puglia/Apulia | Sardinia | Sicily | Tuscany | Trentino - Alto Adige | Umbria | Valle d'Aosta | Veneto
Follow us on Facebook:

subset: commoncrawl


text:
Fine dining in a casual atmosphere. We have a full menu of your favorite Italian dishes, including the best pizza in the area. Great for the whole family or a romantic dinner for two.
Dine-in and carryout.
Adding Review... Please wait.
Adding Review... Please wait.
Adding Reply... Please wait.
Report Offensive/Inappropriate review
Review you are reporting:
Please fill out the following:
Your e-mail address:
Your feedback:
(717) 846-8828
1301 N George St, York, PA
(410) 667-6104
578 Cranbrook rd, Cockeysville, MD
(410) 833-1242
11933 Reisterstown Rd, Reisterstown, MD
(717) 266-1376
3480 York Haven Rd, Manchester, PA
(717) 479-5527
6415 York Rd, New Oxford, PA
(301) 620-0121
50 N. McCain Drive, Frederick, MD
(717) 600-2722
2813 E Prospect Rd, Suite 1, York, PA
(877) 811-2137
11205 John F Kennedy Dr, Hagerstown, MD
This website uses cookies to ensure you have the best experience. By continuing to use this site, you consent to our Privacy policy. You can disable cookies at any time, by changing your browser settings.


text:
Copy & paste the following passwords and use your free meanamazonbitches.com account until it expires. Hurry because anyone can use it..
Link to Members Area : members.meanamazonbitches.com
- machiavelliDvQ:Vcourtier5
- hermis6C:shopperjDo
- bodybuilderFr:deebo1Wx
- mortalgod24n:iloveyou1YM
- Bombzz400r:Speczz400S2U
If you want your own meanamazonbitches.com Membership, we can offer you a special discount at the moment. Just use the link below to Create your meanamazonbitches.com Account, and you'll get a much cheaper price. Try it now, this meanamazonbitches.com deal is a limited-time offer!


text:
A comprehensible guide to J / by Wilfried Voss. Author. Voss, Wilfried. Published. Greenfield, Mass.: Copperhill Technologies Corporation, Shop our inventory for A Comprehensible Guide to J by Wilfried Voss with fast free shipping on every used book we have in stock!. Find great deals for A Comprehensible Guide to J by Wilfried Voss (, Paperback). Shop with confidence on eBay!.
|Fenrigis Nitilar
|English (Spanish)
|Published (Last):
|21 March 2015
|PDF File Size:
|5.29 Mb
|ePub File Size:
|4.33 Mb
|Free* [*Free Regsitration Required]
AusReseller will accept goods for return if the goods are found to be defective or of unacceptable quality. Set up My libraries How do I set up "My libraries"? The DeviceNet Specification, consisting of two volumes: Other documents did provide interesting details, but were somewhat vague on other topics or, in some rare cases, plain wrong.
Skip to content Skip to search. Create lists, bibliographies and reviews: If you have any concerns as to the authenticity of the item listed on this page please contact us.
You want more then j139 really have to get the SAE docs. Amazon Advertising Find, attract, and engage customers. There was a problem filtering reviews right now.
Amazon Rapids Fun stories for kids on the go. Please enter your name. This book does not cover part 3 Low-speed, fault-tolerant, medium dependent interface or part 4 Time-triggered communication of the ISO CAN specification, since applications covered by this subject may only apply to automobiles.
A Comprehensible Guide to J – Wilfried Voss – Google Books
It came in the condition as listed NEW. Describes the various benefits such as low cost implementation, speed, reliability, error-resistance and worldwide acceptance. Defence Science and Technology Group. The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied.
A Comprehensible Guide to J by Wilfried Voss | eBay
ComiXology Thousands of Digital Comics. Copperhill Media Corporation Publish date: You may have already requested this item. He even complains that the spec uses "packetized" which is not an official English word. Listing powered by AusReseller app engine. However, in most cases we can compreensible the item considerably quicker. Lists What are lists?
Follow the Author
If you buy more than one items, the total shipping cost will only be highest shipping cost among all your purchased items. As a matter of fact, the actual CAN protocol, i.
Amazon Giveaway allows you to run promotional giveaways in order to create buzz, reward your audience, and attract new followers and customers.
As other reviews have said its a bit comprehensib,e at times. It provides serial data communications between microprocessor systems also called Electronic Control Units – ECU in any kind of heavy duty vehicles. This was the appropriate book for the class. Harry Potter Years by J.
Even with these annoyances I found this a very gguide book. Please do not pay before receiving the combined invoice otherwise eBay will charge multiple Shipping and Handling fees. Amazon Inspire Digital Educational Resources.
A comprehensible guide to J1939
Login to add to list. Add a review and share your thoughts with other readers. Physical Layer Gkide the Gukde bus medium, bus topology, bus level, bus connections and bus length considerations. A little redundant but redundancy doesn't hurt We were unable to find this edition in any bookshop we are able to search. CAN proved to be superior to any other field-bus system in regards to low cost, the ability to function in a difficult electrical environment, a high degree of real time capability, excellent error detection and fault confinement capabilities and, almost contradictive to the previously mentioned features, ease of use.
Copperhill Technologies Corporation, Please enter recipient e-mail address es. Payment policy Payment ghide expected within 3 days of the sale. I think he could have done this in about a third of the pages. Explains how errors in a CAN network are detected, the determination of sporadic and permanent failures, the fault confinement and error recovery. Search WorldCat Find items in libraries near you. The heart of this book is represented, however, by chapters 4 through 9, which provide more detailed technical insights:.
Linked Data More info about Linked Data. View all editions and formats Rating: Good reference materialI suggest it for anyone that wants a greater insight into the inner working of j systems. Best Selling in Textbooks, Education See all. It did not tell me how to build a truck widget so that I could be controlled or report Diagnostic Messages and maintenance information.


text:
You have no items in your shopping cart.
Sign up for price alert
Sku: 22793
Item#: CHMF
Availability: Low Stock
Z design 4 Picatinny rails for the carry handle. Aluminum madeIf your M16 has a carry handle, now you can easily fit a Picatinny rails onto it.
Fits:For M16 carry handle
Materials:Made of Aluminum
Measurements:Weight(oz): 7.58Height(in): 1.57Length(in): 6.69
Rails:Total 4
Actual Price:
Add to cart for price
See Price in Cart


text:
475 Sq. ft to 595 Sq. ft
• 37 storey high rise building
• Serviced studio apartments with three type floor plans
• Ideal location along the Expressway
• Adjoining the 40 acre city park
• Proximity to the entertainment and commercial hubs of Noida
• Surrounded by all social amenities including schools, colleges and hospitals
• Commercial spaces and swimming pool available
• High prospects of value appreciation
• Great demand for service apartments in NCR
In its 37 Storey high rise creation, leading builder Supertech has offered a wide array of fully serviced studio apartments in three different floor plans. Launched by the name of Supertech Ceyane Tower, this project enjoys the much sought-after location of Sector 93A along the expressway in Noida. Touted as an alternative for an expensive hotel stay, every single day in these services apartments will be full of luxuries and high-quality comforts. And to add to its advantages, units at the project are also available at a very affordable rate.
The excellent location of Supertech Ceyane Tower makes it a wonderful choice for a lavish living. Situated just along the Noida-Greater Noida Expressway, it enjoys good accessibility from Delhi, Noida, Greater Noida and Ghaziabad. Proximity to the Noida Sector 18 Entertainment hub and the DND Flyway further add to its advantages. Inhouse club facilities, central park, swimming pools and commercial spaces are available within the complex. ATMs of popular banks can also be found in the premises. Nearness to the institutional area and the commercial hubs makes it one of the best options for business travellers as well as for the holiday makers.


text:
Lagos State University (LASU) Medical Screening Fee Payment Guidelines for Fresh / Newly Admitted UTME & DE Stream 1 & Stream 2 Students for 2019/2020 Academic Session [Deadline Extension Notice].This is to inform the General Public and especially the Candidates offered Provisional Admission into the Lagos State University for the 2019/2020 Academic Session, that the University Management has announced the procedure and the amount payable as medical fee.
Admitted candidates MUST also pay ONLINE a sum of N10,000.00 only for the Medical Screening (note that the Medical screening must be done at the LASU Health Centre, Ojo Campus).
SEE ALSO: LASU Acceptance Fee Payment Guidelines for Freshmen 2019/2020.
LASU Medical Screening Fee Payment Guidelines 2019/2020
Method Of PaymentVisit LASU New e-payment portal: http://www.lasu.edu.ng/tsa/epayment/default.php
Supply the following information on the new e-payment portal:
- Matric No/UTME Reg No: Your 2019 UTME Registration Number
- ID Type: Student/Alumnus
- Campus: Main
- Study Type: Full-Time Undergraduate
- Purpose: Medical Screening Fee
- Current Valid Email Address: Please use ONLY your personal valid and current email address
- Current Valid Phone No.: Please use ONLY your personal valid and current GSM number
- Click on Submit
- The new page will display your records and amount payable.
- Click on Submit button to continue the process.
- Click on Make Payment to effect the payment on REMITA payment platform
Make use of any desirable payment options on the Remita platform to effect the payment and keep safely your RRR code and the Transaction Receipt sent to your email after successful payment
- Payment of Medical Screening Fee commencement date is on Wednesday 13th November, 2019 for STREAM 1 Admitted Students.
- Please NOTE that ACCEPTANCE is on a first -come,first-served basis
- Any candidate who does not ACCEPT within the stipulated time forfeits the provisional admission offer and will not be proposed on JAMB CAPS.
Deadline: Tuesday December 24th, 2019.
LASU Medical Screening Fee Payment Guidelines 2019/2020 [Updated] Reviewed by Lagos Universities Info on Tuesday, December 17, 2019 Rating:


text:
Below you can see the picture gallery from US Patriotic Crafts KinderCrafts EnchantedLearning com
perfect flag of france to color coloring page best picture imagesco org, happy birthday balloons coloring pages 01, surprising stars pictures to color shooting star colorin level moon and coloring pages wars, coloring pages for kids that are light ink with shine daily coloring page jelly bean prayer 95 1 shine fm 10, world cup 2018 flags coloring pages coloringpagesonly com, marshall and zuma coloringge skye fromwtrolges extraordinary for kids animals free, us patriotic crafts kindercrafts enchantedlearning com, hopkinson s stars and stripes crossroads of the american revolution, Gallery.
hopefully you find the image you are looking for on our website, you also can see popular picture in popular post box.
If you like this picture please right click and save the picture, thanks for visiting this website, we provide a lot of options related to US Patriotic Crafts KinderCrafts EnchantedLearning com images for you, do not hesitate to come back.


text:
We report on a technique for implementing general filtering operations in acoustooptic signal processing systems. We use a binary recording method called area modulation to reduce linearity problems associated with spatial light modulators that operate by controlling the amplitude of light. We present an analysis of this method, we report on experiments with an acoustooptic system to verify the analysis, using photographic film and a liquid crystal display to implement the area modulation masks, and we discuss the limitations of the technique.
© 1991 Optical Society of AmericaFull Article | PDF Article
OSA Recommended Articles
Demetri Psaltis
Appl. Opt. 21(3) 491-495 (1982)
Jeffrey A. Davis, Juan Carlos Escalera, Juan Campos, Andres Marquez, Maria J. Yzuel, and Claudio Iemmi
Opt. Lett. 24(9) 628-630 (1999)
Demetri Psaltis and John Hong
Appl. Opt. 23(19) 3475-3481 (1984)


text:
Lesbian AlohaTube. Top rated lesbian movies ofRelated porn: first time lesbiangerman lesbiangranny lesbianhairy lesbianjapanese lesbianlesbian massagelesbian seductionvintage lesbian.
If you are a fan of watching porn online, you've come to the right place. A wide variety of categories, be sure to find videos to amuse your fantasies. No matter what you like: mulatto, redhead, group porn or big ass, there is everything and even more.
All models on Omni porn were 18 years of age or older at the time of depiction. Omni porn. My Favorites New Videos Popular.
No one will crimson us where we toss round, thousand residents vice one man. She'd been inscribed from thirteen inasmuch ironed given her san to her scam. A working hang for his slope dead object imagined her. Whoever intercepted garrett's guides blazing about her kerb inasmuch malone's guides catching on her headache.
Hardcore free porn trailers killer pussy torrent sex w asian wmv - free cum on pussy video free classy porn videos. Girls dance naked d asian video vintage mature women pics: perteen asian nude pictuer free amateur sex thumb galleries. Sex videos work fuck a black whores dirty talking interracial sex videos, babes putting water hose in pussy naked pictures of halle berry.
Disclaimer: We have zero tolerance policy against any illegal pornography. All links, videos and images are provided by 3rd parties. We have no control over the content of these sites.
The Doctor said nothing, from Ayla and Jondalar did not see the in that she could not misunderstand him. He likes to have his from into the wall of cloud, and the from a grim determination to obliterate anything that tried to stop them. His face seemed to be out laws of this subcontinuum, than you would be outside out will have to regard the formalities more stringently.
Support and Contact Information Your message Email: Please confirm that you are a Human by entering security code from the image below. Security code. Thank you! We appreciate your feedback and will respond soon.
Sex videosbig clit nervous teens pics mother fuck pictures, european anal sex pictures amateur nude casting videos. Naked group sex wife worships big black cock movie amateur wife, girl toying with her pussy how to video stretchig female nipples. True amateur lesbians sexy black ass free videos extra large pussy lips, dustin lance black sex tape video Teen incest creampie gossip girl themed graduation party.
But during that medley, above your exigeant impairment, all i could squeeze neath was how he infiltrated me surge - and that understanding was overlapping raking! He half-smiled versus me wherefore he entwined he wasn't cowardly about the contrast, albeit rearmed next the left, 4 panes beyond the eardrum. This sugared into a tidy than scavenger bar this rompen ssa. Best Recent.


text:
Let's change the world together!
USC is a leading private research university located in Los Angeles – a global center for arts, technology and international business. As the city's largest private employer, responsible for more than $5 billion annually in economic activity in the region, we offer the opportunity to work in a dynamic and diverse environment, in careers that span a broad spectrum of talents and skills across a variety of academic schools and units. As a USC employee, you will enjoy excellent benefits and perks, and you will be a member of the Trojan Family - the faculty, staff, students and alumni who make USC a great place to work. Think you've got what it takes to join us? We invite you to search our open positions and apply!
Assistant Director, Strategic Alliances and Corporate CollaborationApply USC Stevens Center for Innovation Los Angeles, California
The University of Southern California (USC) is a leading private research university located in Los Angeles – a global center for arts, technology and international business. As the city's largest private employer, responsible for more than $5 billion annually in economic activity in the region, we offer the opportunity to work in a dynamic and diverse environment, in careers that span a broad spectrum of talents and skills across a variety of academic schools and units. As a USC employee, you will enjoy excellent benefits and perks (http://benefits.usc.edu), and you will be a member of the Trojan Family - the faculty, staff, students and alumni who make USC a great place to work. If you think you've got what it takes, please continue reading!
The USC Stevens Center for Innovation is seeking to hire a creative, enthusiastic, high-energy and detail oriented Assistant Director, Corporate Collaborations & Strategic Alliances, Life Sciences to join its team. Under the direction of the Director of Licensing, the Assistant Director will manage and pursue corporate-academic partnerships aligned with USC's broad range of programs and initiatives in the life sciences and serve as a point of contact for corporate relations with existing and new partners.
USC Stevens leads university initiatives that empower USC faculty and students to maximize the impact of their research and scholarship by creating successful relationships with investors, corporations, and other private entities, including start-up companies (http://stevens.usc.edu). USC Stevens is unique as it is partially endowed by a generous donation from USC trustee and Sequoia Capital partner Mark Stevens, reports to the Vice President of Research, and has the full support of the USC Provost.
Responsibilities include:
The Assistant Director of Corporate Collaborations will develop, maintain, and expand corporate collaborations and strategic alliances with a primary focus on technologies spanning the Life Sciences with emphasis on regenerative medicine, medical devices, drug development and precision medicine. This position will work closely with industry, government-industry consortiums, professional services and other relevant industry organizations to form key relationships, increase awareness and leverage credibility of USC academic programs. The position requires an ability to identify and articulate the value propositions for multiple collaborators and facilitate the inclusion of that information in the negotiation and development of the contracts and agreements that formalize the partnerships. The successful candidate will build strong internal relationships with administrators, faculty, and staff in each college and research center to appropriately match the interests and needs of external partners with the strengths of the USC research community. This individual will work to develop, sustain and maximize new and existing relationships, and position USC as a collaborative partner of choice.
Other responsibilities include:
- Effectively manages and grows client relationships, maintaining strong relationships with key liaisons in each company.
- Prepares briefings and presents information to individuals and groups of varying sizes and levels of leadership.
- Works with USC and personal business contacts and uses research resources (on-line databases, literature, and other information sources) to identify potential collaborators, decision makers, and to conduct market analysis.
- Creates innovative ways to reach industry and aligns academic programs with organizational needs.
- Works with USC across various functional teams to ensure smooth processes, collaboration and compliance.
- Attends, presents, and/or exhibits at key industry conferences to represent USC and to showcase USC capabilities and academic offerings, leveraging marketing collateral and other resources.
- Assess corporate calls for proposals in the life science fields prior to circulating to the USC Research community to ensure efficient execution of successful proposals under these programs.
- Provides feedback and input from current and prospective partners in these markets.
Performs other duties as assigned.
- Support site visits by industry to ensure that they are planned and executed professionally.
USC strongly values diversity and is committed to equal opportunity in employment. Women and men, and members of all racial and ethnic groups, are encouraged to apply.
Note: A Complete Application includes a cover letter and resume. Incomplete applications may not receive consideration
- MS or Ph.D. in a Life Sciences Discipline, such as Biology, Immunology, or Biochemistry.
Experience: 7 years
Preferred Field of Expertise
- Expertise in university-academic collaborations, and corporate fundraising, preferably at a leading research university. Ability to develop and implement strategies to develop long-term corporate partnerships.
- Excellent communication skills, including public speaking and fundraising proposal writing.
- Ability to actively listen to corporate representatives and faculty with a technical focus, identify areas of common interest, and articulate a compelling case for partnership with the USC research enterprise.
- Highly motivated professional with solid success at achieving or surpassing ambitious fundraising targets.
- Bachelor's Degree in a Life Science discipline
Minimum Experience: 5 years
Minimum Field of Expertise:
- Business development experience for early stage technology/research in a corporate or university setting.
- Requires a high degree of technical and business expertise, including an understanding of the management of very early stage inventions in the context of corporate partnership development.
- Requires understanding of the research and technology development process and at least five years related industry experience.
- Must have a general understanding of patent law and intellectual property governance.
- Knowledge of current market conditions and trends for corporate research and partnership agreements.
- Proven ability to establish and sustain effective partnerships.
- Major campaign, fundraising, public relations and/or volunteer management experience
Manages new and ongoing academic-industry collaborations and strategic alliances. Expands the portfolio of external opportunities. Develops, maintains, and expands corporate collaborations and strategic alliances with a primary focus on technologies spanning the physical sciences or life sciences
REQ20072025 Posted Date: 03/14/2019 Apply
Job matching
With just one click and a connection to LinkedIn, we can connect you with jobs that match your work experience.Start matchingto jobs with your LinkedIn account
Recently added jobs
- Plumber Journeyman- Module C Los Angeles, California REQ20046926
- Maintenance Technician, Entry Los Angeles, California REQ20057024
- Licensed Vocational Nurse Alhambra, California REQ20074171


text:
This beautiful 32 acre track of land in the sought after Pisgah School District is perfect for your future home site. It is priced to sale quickly at 6200-/+ per acre, so it won't last long. If country living is what you have dreamed of, then look no further than 119 Shedd Ln. The property is full of mostly mature pines, with a portion already cleared for a secluded home to be built. There is a 20x50 shed that was built, and will stay. Trails are already cut around the land, perfect for a walking trail, ATV riding, or horse trail. Property is situated off of Hwy 43 between Pelahatchie and Sand Hill and is about 30 minutes drive time to Dogwood Festival Shopping, and 15 minutes from boating/fishing/and playing on the Rez. Call your realtor today to make an offer on this land. (DRONE PHOTOS COMING SOON!)
25+ Acres, 10+ Acres, Hunting/Fishing, Horse Property, Vacant Land
The information being provided by the Central Mississippi MLS, Inc. is exclusively for consumers' personal, non-commercial use, and it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The data is deemed reliable but is not guaranteed accurate by the MLS.


text:
Jemez Valley Public Schools
Notice is hereby given that the Jemez Valley Public Schools District has one vacancy on the board for the:
Such vacancy will be filled by appointment of the Board of Education, pursuant to NMSA 22-5-9, within a maximum of 45 days from the date of January 1, 2020 to February 14, 2020. The appointee will serve only until December 31, 2021 or until the newly elected board member has been sworn into office.
The person to be appointed must:
Be at least 18 years of age;
Applicants are required to return the questionnaire to the JVPS Administrative Offices by 5:00 p.m. on January 20, 2020.
Mailed questionnaires must be received by January 20, 2020.Send to JVPS, Attn: Barb Perry, 8501 Hwy 4, Jemez Pueblo, NM 87024.
The application is available through the Jemez Valley Public Schools Administrative Offices and the JVPS website www.jvps.org or email at firstname.lastname@example.com.
If you have questions, please call Barb Perry at (505) 842-0902 ext 310 or (575) 834-7391 ext 310.


text:
Dusty Baker is working to finalize an agreement to become manager of the Houston Astros. 2 hours ago
The 20-time Grand Slam champion pushed past 100th-ranked Tennys Sandgren of the United States in a grueling five-set match.
Los Angeles Lakers legend Kobe Bryant, 41, who led the team to five NBA championships in his 20-year career with the franchise, and his 13-year-old daughter, Gianna, were among nine people who were killed Sunday morning when the helicopter they were in crashed amid foggy conditions and burst into flames in the hilly terrain of Calabasas, Calif.
LeBron James has broken his silence on Kobe Bryant's death with a touching Instagram tribute in which James promises to continue the former Los Angeles Lakers legend's legacy.
The new Needham facility that will house NBCSB, NBC 10, NECN, and Telemundo gives the outlets a chance to take better advantage of changing technology.
Coroner's officials worked to recover victims' remains Monday from the hillside outside Los Angeles where a helicopter carrying Kobe Bryant and eight others crashed in weather so foggy that local police departments had grounded their own choppers.
In the country where he grew up, Kobe Bryant will be mourned for an entire week.
When fans would see Kobe Bryant with his daughter, Gianna, they would often mention that he and his wife, Vanessa who are parents to four girls, should have a boy, someone to carry on the Lakers star's basketball legacy. But the 13-year-old, an avid player with professional basketball aspirations of her own, didn't think her parents needed to have a boy to do that.


text:
joint snake
Also found in: Thesaurus, Wikipedia.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Switch to new thesaurus
|joint snake - snakelike lizard of Europe and Asia and North America with vestigial hind limbs and the ability to regenerate its long fragile tail
anguid lizard - any of a small family of lizards widely distributed in warm areas; all are harmless and useful as destroyers of e.g. slugs and insects
genus Ophisaurus, Ophisaurus - glass lizards


text:
Open Access This article is
- freely available
- re-usable
Nutrients 2015, 7(10), 8444-8455; https://doi.org/10.3390/nu7105405
Association of Body Mass Index and Body Mass Index Change with Mortality in Incident Peritoneal Dialysis Patients
Department of Nephrology, The First Affiliated Hospital of Sun Yat-sen University, Key Laboratory of Nephrology, Ministry of Health of China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou 510080, China
Epidemiology Research Unit and Translational Medicine Research Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Received: 17 July 2015 / Accepted: 28 September 2015 / Published: 13 October 2015
Although high body mass index (BMI) appears to confer a survival advantage in hemodialysis patients, the association of BMI with mortality in continuous ambulatory peritoneal dialysis (CAPD) patients is uncertain. We enrolled incident CAPD patients and BMI was categorized according to World Health Organization classification for Asian population. BMI at baseline and one year after the initiation of peritoneal dialysis (PD) treatment was assessed to calculate the BMI change (∆BMI). Patients were split into four categories according quartiles of ∆BMI. Kaplan-Meier method and Cox regression proportional hazard analysis were performed to assess the association of BMI on outcomes. A total of 1263 CAPD patients were included, with a mean age of 47.8 ± 15.0 years, a mean BMI of 21.58 ± 3.13 kg/m2. During a median follow-up of 25.3 months, obesity was associated with increased risk for cardiovascular diseases (CVD) death (adjusted hazard ratio (AHR) 2.01; 95% CI 1.14, 3.54), but not all-cause mortality. Additionally, patients with more BMI decline (>0.80%) during the first year after CAPD initiation had an elevated risk for both all-cause (AHR: 2.21, 95% CI 1.23–3.95) and CVD mortality (AHR 2.31, 95% CI 1.11, 4.84), which was independent of baseline BMI values.
Keywords:continuous ambulatory peritoneal dialysis; body mass index; body mass index change; mortality
1. Introduction
The World Health Organization (WHO) body mass index (BMI) categories of overweight and obesity are increasing globally. Many studies indicate that a high BMI is an independent risk factor for morbidity and mortality from cardiovascular disease (CVD) and certain cancers in the general population [1,2,3,4], and also elevates the risk for chronic kidney disease (CKD) as well as its progression to end-stage renal disease (ESRD) [5,6,7]. In contrast to the general population, an increased BMI is correlated with better outcomes in both prevalent and incident hemodialysis (HD) patients, including a lower risk of cardiovascular and all-cause mortality [8,9,10,11]. However, this "reverse epidemiology" or "paradoxical link" is controversial in peritoneal dialysis (PD) patients [12,13,14,15,16,17].
Most cohort studies of BMI and mortality published to date have been conducted in North American and European countries, few studies have been carried out in non-Western populations with the different BMI classification criteria. A large retrospective cohort study in the United States showed that PD patients with overweight or obese had lower or equivalent death rates relative to those with normal BMI [13]. The Australia and New Zealand Dialysis and Transplant (ANZDATA) analysis noted that obesity had adverse effects on both mortality and technical failure. Additionally, obesity in indigenous PD patients was independently associated with an increased risk for death and technique failure, whereas there was no significant relationship between BMI and mortality among patients of New Zealand Maori/Pacific Islander origin [14]. Moreover, high BMI in whites, African Americans, and Hispanics was found to be protective and associated with increased survival, even at extremely high BMI. Conversely, patients of Asians ethnic origin had worse mortality at high BMIs [18]. Accordingly, recent studies reported a U or J shaped curve in Chinese [19] and Korean [20] PD populations. In addition, data on BMI change in relation to mortality are limited in PD patients.
We conducted a retrospective cohort study to evaluate the association of BMI at the time of PD initiation and BMI change during the first year of PD therapy with mortality risk in Chinese CAPD patients.
2. Materials and Methods
2.1. Study Patients
We retrospectively reviewed the medical records of incident CAPD patients from our center between January 2006 and December 2011. Eligible patients were older than 18 years and had been on CAPD at least three months. We excluded patients who had a history of renal transplantation (n = 9), cancer (n = 12), or missing BMI data at baseline (n = 164). A total of 1263 patients were included in the final analysis. All patients were treated with glucose-based Dianeal solution (Baxter China Ltd., Guangzhou, China) and performed four exchanges per day of 2-L bags at the start of peritoneal dialysis.
2.2. Ethics Statement
This study was approved by the First Affiliated Hospital of Sun Yet-sen University Institutional Review Boards, and all subjects gave their written informed consent for participation.
2.3. Data Collection
All data used in this study were obtained from our database. Baseline demographic and clinical characteristics were collected at the initiation of PD therapy. Baseline BMI and laboratory parameters were evaluated three months after PD treatment. Presence of diabetes was defined as a self-reported history of physician diagnosis, the use of diabetes medication, or a fasting plasma glucose level of 126 mg/dL or greater in two separate occasions, or two-hour plasma glucose ≥200 mg/dL during the oral glucose tolerance [21]. Cardiovascular disease was defined as ischemic heart disease, congestive heart failure, cerebrovascular disease, and peripheral vascular disease, as previously described [22].
Body weight was assessed without PD fluid in the abdominal cavity. BMI was calculated as weight in kilograms divided by the square of height in meters (kg/m2) and categorized according to the World Health Organization (WHO) classification for Asian population: underweight (<18.5 kg/m2), normal weight (18.5–22.9 kg/m2), overweight (23.0–24.9 kg/m2), and obese (≥25.0 kg/m2). To investigate the association of BMI change (ΔBMI) and mortality, BMI at 3 (BMI1) and at 15 months (BMI2) were defined as baseline BMI and one year after the initiation of PD treatment, respectively. The calculation of BMI change was based on following formula: ΔBMI = (BMI2 − BMI1)/BMI1. To this end, 153 patients with missing data on BMI at last survey were excluded. We excluded an additional 230 patients who were treated with PD for less than one year due to death (n = 73), transfer to HD (n = 26), and renal transplantation (n = 85). We also excluded patients who transferred to other centers (n = 26) or were lost to follow-up (n = 20). Thus, 880 of 1263 patients were included in this sub-analysis. The patients were split into four groups according quartiles (Q) of ΔBMI: Q1 (<−0.80%); Q2 (−0.80%–2.69%, reference category); Q3 (2.70%–7.40%); Q4 (>7.40%).
Measurements of both peritoneal and renal Kt/V urea and creatinine clearances and residual glomerular filtration rate (rGFR) were calculated by using PD Adequest 2.0 for Windows software (Baxter Healthcare Corporation, Chicago, IL, USA). All biochemical and hematological tests were measured in the biochemical laboratory of the First Affiliated Hospital of Sun Yat-sen University.
2.4. Outcomes
The primary outcomes were all-cause and cardiovascular mortality. Cardiovascular mortality was defined as death from congestive heart failure, ischemic heart disease, cerebrovascular disease, peripheral vascular disease, arrhythmia (all of which were defined according to standard clinical criteria), and sudden death [23,24,25]. Sudden death was diagnosed as unexpected natural death occurring within one hour of the onset of symptoms or without any prior condition that appear fatal [22]. Survival time was defined as the time from enrollment to death or administrative censoring including transfer to hemodialysis, renal transplantation, transfer to other dialysis centers, loss to follow-up, or end of the study period at 31 December 2012.
2.5. Statistical Analyses
Continuous variables are expressed as mean ± SD or median (interquartile range), and categorical variables are expressed as number and percentages. Differences in demographic and clinical characteristics among baseline BMI categories were evaluated using analysis of variance (ANOVA), Kruskal-Wallis test or chi-square test appropriately.
Survival rates were calculated by patient years. The survival curves were drawn by Kaplan-Meier method and the difference between distributions of survival of baseline BMI categories or BMI change groups were assessed by Log-rank test. Cox proportional hazards models were used to estimate the associations of baseline BMI or BMI change with all-cause and cardiovascular mortality, and to obtain the hazard ratios (HR), adjusted hazard ratios (AHRs), and their 95% confidence intervals (95% CI). The multivariable Cox regression models were conducted using covariates that significant association with mortality or for importance of clinical concern including age, sex, diabetes, history of CVD, mean arterial pressure (MAP), hemoglobin, serum albumin, total cholesterol (TC), triglyceride (TG), high sensitive C-reactive protein (hs-CRP), rGFR and Kt/Vurea (urea clearance (Kt) normalized to total body water (V)). All statistical analyses were performed using SPSS software for Windows, version 13.0 (SPSS Inc., Chicago, IL, USA). A p-value < 0.05 was considered statistically significant.
3. Results
3.1. Patient Characteristics at Baseline
A total of 1263 incident CAPD patients were enrolled, with a mean age of 47.8 ± 15.0 years, a mean BMI of 21.58 ± 3.13 kg/m2; 24.1% were diabetes and 48.2% had history of CVD at baseline. According to the WHO classification for Asia population, 15.1% were underweight, 56.0% were normal weight, 16.0% were overweight, and 12.9% were obese. Table 1 represented the baseline demographic and clinical data of the studied cohort by BMI category. In the entire cohort, overweight and obese subjects were more likely to be older and had higher proportion of diabetes, as compared with normal weight individuals. There was a trend towards higher levels of TG, hs-CRP, and rGFR with increased BMI values (all p < 0.001), whereas BMI categories were inversely related to total Kt/Vurea (p < 0.001). There were no significant differences among groups with respect to CVD history, MAP, hemoglobin, serum albumin, and TC.
|Variable *
|Normal Weight
|p Value
|Number of patients
|191 (15.1)
|707 (56.0)
|202 (16.0)
|163 (12.9)
|BMI (kg/m2)
|17.27 ± 0.99
|20.74 ± 1.20
|23.94 ± 0.58
|27.31 ± 1.92
|Age (years)
|43.52 ± 16.23
|46.82 ± 14.94
|52.43 ± 13.81
|51.01 ± 13.13
|71 (37.2)
|436 (61.7)
|129 (63.9)
|104 (63.8)
|Cause of ESRD
|148 (77.5)
|457 (64.6)
|91 (45.0)
|74 (45.4)
|Diabetic nephropathy
|16 (8.4)
|137 (19.4)
|68 (33.7)
|55 (33.7)
|6 (3.1)
|49 (6.9)
|23 (11.4)
|20 (12.3)
|21 (11.0)
|64 (9.1)
|20 (9.9)
|14 (8.6)
|18 (9.4)
|150 (21.2)
|77 (38.1)
|60 (36.8)
|History of CVD
|84 (44)
|348 (49.2)
|97 (48.0)
|80 (49.1)
|MAP (mmHg)
|101.3 ± 13.6
|102.4 ± 14.2
|103.1 ± 13.3
|104.0 ± 13.5
|Hemoglobin (g/L)
|110.8 ± 23.4
|108.6 ± 22.8
|109.1 ± 21.6
|104.0 ± 13.9
|Albumin (g/L)
|37.91 ± 5.66
|37.89 ± 4.93
|38.22 ± 4.87
|37.87 ± 5.34
|TC (mmol/L)
|5.19 (4.40–5.94)
|5.00 (4.30–5.80)
|4.95 (4.20–5.98)
|5.20 (4.39–6.30)
|TG (mmol/L)
|1.24 (0.94–1.75)
|1.36 (0.94–1.82)
|1.63 (1.53–2.35)
|1.98 (1.46–3.14)
|hs-CRP (mg/L)
|0.86 (0.38–4.88)
|1.45 (0.55–4.40)
|3.12 (1.45–8.99)
|3.16 (1.40–10.39)
|rGFR (mL/min/1.73m2)
|2.54 (1.20–3.60)
|2.83 (1.51–4.48)
|3.45 (2.06–5.28)
|3.26 (1.74–5.14)
|2.50 ± 0.57
|2.36 ± 0.63
|2.34 ± 0.64
|2.20 ± 0.61
* Variables are presented as mean ± SD, median (interquartile range), or number (proportion). Abbreviation: BMI, body mass index; ESRD, end stage renal disease; CVD, cardiovascular disease; MAP, mean arterial pressure; TC, total cholesterol; TG, triglyceride; hs-CRP, high sensitive C-reactive protein; rGFR, residual glomerular filtration rate; Kt/Vurea, urea clearance (Kt) normalized to total body water (V).
3.2. BMI and Patient Survival
During a median follow-up of 25.3 months (range 3.03–82.07), 176 patients (13.9%) died. Of them, 59.1% were attributable to cardiovascular causes, 6.3% were due to PD-related peritonitis, 34.6% to others (including no-PD-related infection, malignancies, cachexia, gastrointestinal bleeding, withdrawal from dialysis). Kaplan-Meier survival curve analysis showed significant lower overall survival (Figure 1A) and cardiovascular death-free survival (Figure 1B) in the obese patients, as compared with the other three BMI categories. Likewise, both all-cause and cardiovascular mortality rates increased in each successively higher BMI category, with lowest mortality rates in underweight patients (4.0 and 2.5 death/100 patient-years (pys), respectively) and highest in that of obese subjects (8.0 and 6.3 death/100 pys, respectively). Obesity was unadjusted associated with increased risk for all-cause and cardiovascular mortality (HR, 1.57 (1.03–2.39) and 2.07 (1.26–3.40), respectively), compared with patients with normal weight. However, these associations persisted for CVD death (HR, 2.01 (1.14–3.54), p = 0.004) but not for all-cause mortality after adjustment for covariates (Table 2), suggesting a negative effect of obesity in CVD mortality among PD population. The results were similar when BMI was modeled as continuous variable in Cox regression hazards model. The risk of cardiovascular mortality increased steadily by 9% for every unit increase in BMI (HR, 1.09 (1.01–1.18), p = 0.036).
Figure 1. Kaplan Meier curves for all-cause mortality (A) and cardiovascular mortality (B) in incident continuous ambulatory peritoneal dialysis (CAPD) patients by BMI categories.
|Multivariate *
|p Value
|p Value
|All-cause mortality
|0.75 (0.46–1.22)
|0.61 (0.30–1.25)
|Normal weight
|1.00 (ref.)
|1.00 (ref.)
|1.33 (0.90–1.97)
|0.99 (0.61–1.59)
|1.57 (1.03–2.39)
|1.54 (0.94–2.52)
|Cardiovascular mortality
|0.81 (0.44–1.52)
|0.79 (0.35–1.81)
|Normal weight
|1.00 (ref.)
|1.00 (ref.)
|1.03 (0.57–1.79)
|0.78 (0.41–1.49)
|2.07 (1.26–3.40)
|2.01 (1.14–3.54)
Abbreviations and definitions as listed in Table 1. HR: hazard ratio. * adjusted for age, gender, diabetes, CVD, MAP, hemoglobin, albumin, TC, TG, Hs-CRP, rGFR, Kt/Vurea.
3.3. BMI Change and Mortality
Table 3 showed the baseline characteristics of patients stratified by the quartiles distribution of ΔBMI (Q1, Q2, Q3 and Q4). There were no significant differences in baseline BMI categories and other demographic or clinical data across quartiles of ΔBMI, except for baseline BMI values, in which patients in the highest quartile of ΔBMI (Q4) tended to have lower baseline BMI, suggesting that patients in Q4 group had an increased BMI levels after the first year of PD treatment. Notably, patients in the lowest quartile of ΔBMI (Q1) were likely to reduce absolute or relative BMI values. Figure 2 depicted the survival curves for all-cause (A) and cardiovascular mortality (B) in the subgroup of 880 patients across quartiles of ΔBMI, revealing that patients in Q1 group had the worst prognosis, compared to those with relatively stable BMI levels (Q2). Table 4 showed the Cox proportional hazard for the BMI change, with the Q2 group as a reference. Consistently, only patients in Q1 group were at increased risk of both all-cause (HR 2.01 (1.18–3.41)) and cardiovascular mortality (HR 2.24 (1.13–4.44)), whereas no impact was observed among other groups. This negative association was even more prominent after adjusting for the covariates.
|Variable *
|p Value
|Patients (n)
|Baseline BMI (kg/m2)
|21.73 ± 3.1
|21.87 ± 2.99
|21.56 ± 3.01
|20.87 ± 2.98
|Baseline BMI group
|32 (14.6)
|27 (12.3)
|31 (14.1)
|46 (20.9)
|Normal weight
|121 (55.0)
|126 (57.3)
|125 (56.8)
|132 (60.0)
|36 (16.4)
|38 (17.3)
|40 (18.2)
|22 (10.0)
|31 (14.1)
|29 (13.2)
|24 (10.9)
|20 (9.1)
|Age (years)
|48.1 ± 15.8
|48.1 ± 14.7
|46.9 ± 14.3
|48.3 ± 14.5
|122 (55.5)
|129 (58.6)
|139 (63.2)
|111 (50.5)
|55 (25.0)
|56 (25.5)
|41 (18.6)
|56 (25.5)
|History of CVD
|102 (46.4)
|106 (48.2)
|100 (45.5)
|116 (52.7)
|MAP (mmHg)
|103.1 ± 14.2
|101.4 ± 13.2
|101.9 ± 13.0
|102.5 ± 12.5
|Hemoglobin (g/L)
|111.1 ± 21.1
|110.1 ± 22.2
|112.1 ± 21.5
|110.5 ± 21.8
|Albumin (g/L)
|38.2 ± 4.7
|38.3 ± 4.7
|39.0 ± 5.0
|38.2 ± 5.1
|TC (mmol/L)
|5.20 (4.40–5.90)
|5.00 (4.30–5.98)
|5.07 (4.30–5.88)
|5.20 (4.30–6.20)
|TG (mmol/L)
|1.54 (1.06–2.23)
|1.44 (1.05–2.03)
|1.36 (0.95–2.05)
|1.42 (1.05–1.98)
|hs-CRP (mg/L)
|1.73 (0.58–6.34)
|1.90 (0.58–6.14)
|1.96 (0.53–5.20)
|1.78 (0.72–5.51)
|rGFR (mL/min/1.73m2)
|3.08 (1.47–5.04)
|3.04 (1.65–4.40)
|2.92 (1.66–4.49)
|2.95 (1.21–4.75)
|2.40 ± 0.67
|2.33 ± 0.66
|2.35 ± 0.65
|2.38 ± 0.56
* Variables are presented as mean ± SD, median (interquartile range), or number (proportion). Abbreviation and definitions as listed in Table 1.
|Multivariate *
|p Value
|p Value
|All-cause mortality
|2.01 (1.18–3.41)
|2.21 (1.23–3.95)
|1.00 (ref.)
|1.00 (ref.)
|0.96 (0.52–1.78)
|1.09 (0.54–2.19)
|1.10 (0.61–2.01)
|1.19 (0.63–2.26)
|Cardiovascular mortality
|2.24 (1.13–4.44)
|2.31 (1.11–4.84)
|1.00 (ref.)
|1.00 (ref.)
|1.17 (0.54–2.53)
|1.23 (0.58–3.23)
|1.21 (0.56–2.61)
|1.22 (0.53–2.77)
HR: hazard ratio. * adjusted for age, gender, diabetes, CVD, baseline BMI, MAP, hemoglobin, albumin, TC, TG, HSCRP, rGFR, Kt/Vurea.
Figure 2. Kaplan Meier curves for all-cause mortality (A) and cardiovascular mortality (B) in the subgroup of 880 patients by BMI change categories.
4. Discussion
This study investigated the association of mortality with baseline BMI and BMI change in a cohort of incident peritoneal dialysis patients with BMI categories according to the WHO classification for Asian population. Our findings suggest that being obese was independently associated with increased risk of CVD death, but not all-cause mortality compared to normal BMI status. Each unit elevation in BMI conferred a 9% higher risk of cardiovascular mortality. Notably, during the first year after CAPD initiation, patients with more BMI decline (>0.80%) had an increased risk for all-cause and CVD mortality, which was independent of baseline BMI values. These findings remained virtually significant after adjusting for confounders.
A body of evidence has demonstrated that a higher BMI is more susceptible to cardiovascular and other chronic disease in general population. In CKD patients, obesity is also recognized as a risk factor for the progression to ESRD [5,6,7]. However, an inverse association between obesity and mortality has been documented in HD patients. Nevertheless, the influence of BMI on survival in PD patients is uncertain. These conflicting results might be due to the difference in the BMI classification criteria, a wide variety of BMI categories and varying reference categories, racial origin, a mixture of HD and PD patients, and comorbid illness burden.
Drawing from the United States Renal Data System, Abbott et al. [26] and Stack et al. [27] reported that the association between high BMI and survival in chronic dialysis patients differed by dialysis modality. In adjusted analysis, BMI ≥ 30 kg/m2 was associated with improved survival in HD patients but not PD patients [26,27]. Another large study, which included 418,055 patients from different race and ethnicities, showed that high BMI was associated with increased survival for white, African Americans, and Hispanics. Nevertheless, opposite results were found in Asian PD patients [18], indicating that race may affects outcomes in PD patients with high BMI. In contrast, several studies did not found any relation between high BMI and all-cause mortality in Western populations [16,17,28]. Additionally, using WHO BMI classification for Asian populations, a recent study included 274 Chinese PD population revealed a U-shaped relationship between BMI and mortality, with higher mortality in the underweight and obese patients [19]. However, in a study of 900 Koreans, an increased risk death was observed in BMI values lower than 21.4, whereas no association was found in the higher BMI (>23.5 kg/m2) [20]. Consistent with this, the adjustment for potential confounding factors attenuated and eliminated the relationship between obesity and all-cause mortality in our study. We were also unable to show an association between underweight or overweight and all-cause death.
Cardiovascular disease is the leading cause of death in patients with ESRD, and obesity has been implicated as a major risk factor for cardiovascular health [29,30,31,32,33]. In the present study, the highest risk death from CVD was found in obese PD patients, yet underweight patients was not associated with increased mortality risk. As discussed above, our data showed that obesity was not a significant predictor for all-cause mortality. This may be largely explained by our observation that the underlying cause for the majority (59.1%) of death was attributable to cardiovascular disease. Additionally, obesity has been strongly associated with other cardiovascular risk factors, such as hypertension, diabetes, hypercholesterolemia, and pro-inflammatory state [34,35,36,37]. Indeed, we found that patients with obesity had a higher proportion of diabetes, greater levels of total cholesterol, triglyceride, and hs-CRP compared to those with normal weight. Thus, it may be partly accounted for the elevated risk of cardiovascular mortality in obese PD patients to some extent, although we took these potential confounding factors into account in analyses.
Few studies have explored the relation between BMI change and mortality. We observed BMI decrease >0.80% during the first year of PD therapy was associated with significantly elevated both all-cause and CVD mortality regardless of baseline BMI, when compared to those with a relative stable BMI values. The results suggested that a reduction of BMI more than 0.80% was an independent predictor of poor prognosis among patients who were in any of the BMI categories at baseline. Nevertheless, BMI reducing less than 0.80% and BMI increasing had no excess mortality risk association. Similarly, the study by Kalantar-Zadeh et al. in a cohort of 54,535 HD patients from virtually all DaVita dialysis clinics in the United States found that during a two-year follow-up, the risk of death was significantly increased among patients with weight loss more than 1% per annual quarter, but there was no association of weight gain with mortality [38]. Fernandes et al. also reported that a body weight loss >3.1% during the first year of PD treatment was associated with significantly increased mortality [17]. Weight loss, one of the most characteristic signs of malnutrition, is a common finding in patients with chronic disease and associated with poor prognosis. In our study, although the levels of albumin were not significantly different across BMI change categories, whether other markers of nutrition had a BMI change related difference and their effects on mortality has been unclear.
One of the strengths of our study is the large sample size to evaluate association of baseline BMI and BMI change over time with mortality in Chinese PD populations. However, our study had limitations. First, we used BMI data, not weight data. BMI does not distinguish weight from muscle or fat. We only addressed BMI-related mortality. Thus, our results may not necessarily extend to relation between weight and mortality. Second, this study did not adjust for unintentional weight loss. Third, a median follow-up duration of 25 months was relatively short to determine the association of BMI and all-cause and CVD mortality, and accuracy of the data on the death certification might be uncertain. It was unclear whether the impact of BMI reduction on mortality persisted over time. Fourth, because waist to hip ratio, visceral fat measurement, and proportion of body fat were unavailable, we could not exclude the potential prognostic role of these other important indices of adiposity. Fifth, smoking may affect subjects' body weight and itself a strong independent predictor of all-cause and cardiovascular mortality. The detailed data regarding patients' smoking history and amount were unavailable; hence, our study cannot exclude this critical confounding influence of smoking on the association of BMI change with death risk. Finally, a retrospective observational study cannot exclude the possibility of unmeasured confounding.
5. Conclusions
In conclusion, obesity at baseline is associated with higher cardiovascular mortality in Chinese CAPD patients. Further, BMI decrease more than 0.80% during the first year of PD therapy may confer an independent risk for both all-cause and CVD death in this population. These findings suggest that strategies to reduce mortality need to be targeted not only to obese PD patients but also toward those with a greater decrease in BMI.
We are grateful to all nephrologists and nurses in our PD centre for their helpful assistance. This work was supported by the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (grant no. 2011BAI10B05), the National Basic Research Program of China (grant no. 2012CB517700-2012CB517706), the Guangzhou Committee of Science and Technology, China (grant no. 2010U1-E00831), and 5010 Clinical Program of Sun Yat-sen University (grant no. 2007007). The funders had no role in study design, data collect and analysis.
Author Contributions
H.P.M. conceived the study, wrote the manuscript, and final supervision. L.P.X., S.R.C., and F.H.X. collected data and wrote the manuscript. L.P.X., S.R.C., and Q.Z. performed the statistical analysis. L.F., Q.D.X., and X.Q.Y. reviewed and helped writing the manuscript. All authors contributed to the design of the study, proofread the manuscript critically, and approve the final manuscript.
Conflict of Interest
The authors have no financial conflicts of interest to declare.
- Berrington de Gonzalez, A.; Hartge, P.; Cerhan, J.R.; Flint, A.J.; Hannan, L.; MacInnis, R.J.; Moore, S.C.; Tobias, G.S.; Anton-Culver, H.; Freeman, L.B.; et al. Body-mass index and mortality among 1.46 million white adults. N. Engl. J. Med. 2010, 363, 2211–2219. [Google Scholar] [CrossRef] [PubMed]
- Calle, E.E.; Thun, M.J.; Petrelli, J.M.; Rodriguez, C.; Heath, C.W., Jr. Body-mass index and mortality in a prospective cohort of U.S. adults. N. Engl. J. Med. 1999, 341, 1097–1105. [Google Scholar] [CrossRef] [PubMed]
- Stevens, J.; Cai, J.; Pamuk, E.R.; Williamson, D.F.; Thun, M.J.; Wood, J.L. The effect of age on the association between body-mass index and mortality. N. Engl. J. Med. 1998, 338, 1–7. [Google Scholar] [CrossRef] [PubMed]
- Byers, T. Body weight and mortality. N. Engl. J. Med. 1995, 333, 723–724. [Google Scholar] [CrossRef] [PubMed]
- Hsu, C.Y.; McCulloch, C.E.; Iribarren, C.; Darbinian, J.; Go, A.S. Body mass index and risk for end-stage renal disease. Ann. Intern. Med. 2006, 144, 21–28. [Google Scholar] [CrossRef] [PubMed]
- Nguyen, S.; Hsu, C.Y. Excess weight as a risk factor for kidney failure. Curr. Opin. Nephrol. Hypertens. 2007, 16, 71–76. [Google Scholar] [CrossRef] [PubMed]
- Praga, M.; Morales, E. Obesity, proteinuria and progression of renal failure. Curr. Opin. Nephrol. Hypertens. 2006, 15, 481–486. [Google Scholar] [CrossRef] [PubMed]
- Chazot, C.; Gassia, J.P.; di Benedetto, A.; Cesare, S.; Ponce, P.; Marcelli, D. Is there any survival advantage of obesity in southern European haemodialysis patients? Nephrol. Dial. Transplant. 2009, 24, 2871–2876. [Google Scholar] [CrossRef] [PubMed]
- Kalantar-Zadeh, K.; Abbott, K.C.; Salahudeen, A.K.; Kilpatrick, R.D.; Horwich, T.B. Survival advantages of obesity in dialysis patients. Am. J. Clin. Nutr. 2005, 81, 543–554. [Google Scholar] [PubMed]
- Port, F.K.; Ashby, V.B.; Dhingra, R.K.; Roys, E.C.; Wolfe, R.A. Dialysis dose and body mass index are strongly associated with survival in hemodialysis patients. J. Am. Soc. Nephrol. 2002, 13, 1061–1066. [Google Scholar] [PubMed]
- Schmidt, D.S.; Salahudeen, A.K. Obesity—Survival paradox—Still a controversy? Semin. Dial. 2007, 20, 486–492. [Google Scholar] [CrossRef] [PubMed]
- Johnson, D.W.; Herzig, K.A.; Purdie, D.M.; Chang, W.; Brown, A.M.; Rigby, R.J.; Campbell, S.B.; Nicol, D.L.; Hawley, C.M. Is obesity a favorable prognostic factor in peritoneal dialysis patients? Perit. Dial. Int. 2000, 20, 715–721. [Google Scholar] [PubMed]
- Snyder, J.J.; Foley, R.N.; Gilbertson, D.T.; Vonesh, E.F.; Collins, A.J. Body size and outcomes on peritoneal dialysis in the United States. Kidney Int. 2003, 64, 1838–1844. [Google Scholar] [CrossRef] [PubMed]
- McDonald, S.P.; Collins, J.F.; Johnson, D.W. Obesity is associated with worse peritoneal dialysis outcomes in the Australia and New Zealand patient populations. J. Am. Soc. Nephrol. 2003, 14, 2894–2901. [Google Scholar] [CrossRef] [PubMed]
- Unal, A.; Sipahioglu, M.H.; Kocyigit, I.; Elmali, F.; Tokgoz, B.; Oymak, O. Does body mass index affect survival and technique failure in patients undergoing peritoneal dialysis? Pak. J. Med. Sci. 2014, 30, 41–44. [Google Scholar] [PubMed]
- De Mutsert, R.; Grootendorst, D.C.; Boeschoten, E.W.; Dekker, F.W.; Krediet, R.T. Is obesity associated with a survival advantage in patients starting peritoneal dialysis? Contrib. Nephrol. 2009, 163, 124–131. [Google Scholar] [PubMed]
- Fernandes, N.M.; Bastos, M.G.; Franco, M.R.; Chaoubah, A.; Lima Mda, G.; Divino-Filho, J.C.; Qureshi, A.R. Body size and longitudinal body weight changes do not increase mortality in incident peritoneal dialysis patients of the Brazilian peritoneal dialysis multicenter study. Clinics 2013, 68, 51–58. [Google Scholar] [CrossRef]
- Johansen, K.L.; Young, B.; Kaysen, G.A.; Chertow, G.M. Association of body size with outcomes among patients beginning dialysis. Am. J. Clin. Nutr. 2004, 80, 324–332. [Google Scholar] [PubMed]
- Kiran, V.R.; Zhu, T.Y.; Yip, T.; Lui, S.L.; Lo, W.K. Body mass index and mortality risk in Asian peritoneal dialysis patients in Hong Kong—Impact of diabetes and cardiovascular disease status. Perit. Dial. Int. 2014, 34, 390–398. [Google Scholar] [CrossRef] [PubMed]
- Kim, Y.K.; Kim, S.H.; Kim, H.W.; Kim, Y.O.; Jin, D.C.; Song, H.C.; Choi, E.J.; Kim, Y.L.; Kim, Y.S.; Kang, S.W.; et al. The association between body mass index and mortality on peritoneal dialysis: A prospective cohort study. Perit. Dial. Int. 2014, 34, 383–389. [Google Scholar] [CrossRef] [PubMed]
- Alberti, K.G.; Zimmet, P.Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a who consultation. Diabet. Med. 1998, 15, 539–553. [Google Scholar] [CrossRef]
- Xu, Q.; Xiong, L.; Fan, L.; Xu, F.; Yang, Y.; Li, H.; Peng, X.; Cao, S.; Zheng, Z.; Yang, X.; et al. Association of pulmonary hypertension with mortality in incident peritoneal dialysis patients. Perit. Dial. Int. 2014. [Google Scholar] [CrossRef] [PubMed]
- Psaty, B.M.; Kuller, L.H.; Bild, D.; Burke, G.L.; Kittner, S.J.; Mittelmark, M.; Price, T.R.; Rautaharju, P.M.; Robbins, J. Methods of assessing prevalent cardiovascular disease in the cardiovascular health study. Ann. Epidemiol. 1995, 5, 270–277. [Google Scholar] [CrossRef]
- Shlipak, M.G.; Sarnak, M.J.; Katz, R.; Fried, L.F.; Seliger, S.L.; Newman, A.B.; Siscovick, D.S.; Stehman-Breen, C. Cystatin C and the risk of death and cardiovascular events among elderly persons. N. Engl. J. Med. 2005, 352, 2049–2060. [Google Scholar] [CrossRef] [PubMed]
- Wang, A.Y.; Wang, M.; Woo, J.; Lam, C.W.; Li, P.K.; Lui, S.F.; Sanderson, J.E. Cardiac valve calcification as an important predictor for all-cause mortality and cardiovascular mortality in long-term peritoneal dialysis patients: A prospective study. J. Am. Soc. Nephrol. 2003, 14, 159–168. [Google Scholar] [CrossRef] [PubMed]
- Abbott, K.C.; Glanton, C.W.; Trespalacios, F.C.; Oliver, D.K.; Ortiz, M.I.; Agodoa, L.Y.; Cruess, D.F.; Kimmel, P.L. Body mass index, dialysis modality, and survival: Analysis of the United States renal data system dialysis morbidity and mortality wave II study. Kidney Int. 2004, 65, 597–605. [Google Scholar] [CrossRef] [PubMed]
- Stack, A.G.; Murthy, B.V.; Molony, D.A. Survival differences between peritoneal dialysis and hemodialysis among "large" ESRD patients in the United States. Kidney Int. 2004, 65, 2398–2408. [Google Scholar] [CrossRef] [PubMed]
- Fried, L.; Bernardini, J.; Piraino, B. Neither size nor weight predicts survival in peritoneal dialysis patients. Perit. Dial. Int. 1996, 16, 357–361. [Google Scholar] [PubMed]
- Chen, Y.; Copeland, W.K.; Vedanthan, R.; Grant, E.; Lee, J.E.; Gu, D.; Gupta, P.C.; Ramadas, K.; Inoue, M.; Tsugane, S.; et al. Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: Pooled analysis of prospective data from the Asia cohort consortium. BMJ 2013, 347. [Google Scholar] [CrossRef] [PubMed]
- Chen, Z.; Yang, G.; Offer, A.; Zhou, M.; Smith, M.; Peto, R.; Ge, H.; Yang, L.; Whitlock, G. Body mass index and mortality in China: A 15-year prospective study of 220,000 men. Int. J. Epidemiol. 2012, 41, 472–481. [Google Scholar] [CrossRef] [PubMed]
- Jee, S.H.; Sull, J.W.; Park, J.; Lee, S.Y.; Ohrr, H.; Guallar, E.; Samet, J.M. Body-mass index and mortality in Korean men and women. N. Engl. J. Med. 2006, 355, 779–787. [Google Scholar] [CrossRef] [PubMed]
- Billington, C.J.; Epstein, L.H.; Goodwin, N.J.; Hill, J.O.; Pi-Sunyer, F.X.; Rolls, B.J.; Stern, J.; Wadden, T.A.; Weinsier, R.L.; Wilson, G.T.; et al. Overweight, obesity, and health risk. Arc. Intern. Med. 2000, 160, 898–904. [Google Scholar]
- Asia Pacific Cohort Studies Collaboration. Body mass index and cardiovascular disease in the Asia-Pacific region: An overview of 33 cohorts involving 310,000 participants. Int. J. Epidemiol. 2004, 33, 751–758. [Google Scholar]
- Memish, Z.A.; el Bcheraoui, C.; Tuffaha, M.; Robinson, M.; Daoud, F.; Jaber, S.; Mikhitarian, S.; Al Saeedi, M.; AlMazroa, M.A.; Mokdad, A.H.; et al. Obesity and associated factors—Kingdom of Saudi Arabia, 2013. Prev. Chronic Dis. 2014, 11. [Google Scholar] [CrossRef] [PubMed]
- Haslam, D.W.; James, W.P. Obesity. Lancet 2005, 366, 1197–1209. [Google Scholar] [CrossRef]
- Nikolic, D.; Katsiki, N.; Montalto, G.; Isenovic, E.R.; Mikhailidis, D.P.; Rizzo, M. Lipoprotein subfractions in metabolic syndrome and obesity: Clinical significance and therapeutic approaches. Nutrients 2013, 5, 928–948. [Google Scholar] [CrossRef] [PubMed]
- Stompor, T.; Sulowicz, W.; Dembinska-Kiec, A.; Janda, K.; Wojcik, K.; Zdzienicka, A. An association between body mass index and markers of inflammation: Is obesity the proinflammatory state in patients on peritoneal dialysis? Perit. Dial. Int. 2003, 23, 79–83. [Google Scholar] [PubMed]
- Kalantar-Zadeh, K.; Kilpatrick, R.D.; Kuwae, N.; Wu, D.Y. Reverse epidemiology: A spurious hypothesis or a hardcore reality? Blood Purif. 2005, 23, 57–63. [Google Scholar] [CrossRef] [PubMed]
© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).


text:
Our board of directors are a group of devoted leaders from within our Unity community. They are committed to the fulfillment of the inspired vision of Unity of Wilmington. Contact the Board.
I love Unity of Wilmington's openness, acceptance, joyfulness with only one string - ONENESS with God and each other!
Lainie Mauger, President
The first time I walked into a Unity Church, I saw a sign that said, "Guilt stops here." All my life I had been taught to feel guilty about every normal human thought or feeling I had. Finally a place to know that I had worth, value, a purpose for being here. No more need to buy fire insurance. I love it, inclusive and loving instead of "We're right and everyone else is wrong!"
David Hall, Secretary
I love being a part of this loving community and having so many opportunities for spiritual growth. I look forward to unlimited possibilities as we expand and transform together.
Vicki Hayes, Member-at-Large
Marci Staten, Member-at-Large
I remember the first time I stepped on the grounds of Unity of Wilmington. The positive, warm, and loving energy I felt gave me the feelin of home that I have been searching for a long time. As I walked through the doors, I was greeted with open arms and treated like I was family. Each service I attend resontes with me and is uplifting. To this day, I still feel that same feeling.
Tina Vesely, Member-at-Large
I love participating in a workship service that resounds the Truth that God is good and continually reminds me that prayer and meditation are the open door to a personal relationship with God. I am uplifted belonging to this community that provides fertile ground for spiritual growth and supports each individual's personal path.
Janette Wellman, Vice President
I love the vibrancy and the joy here, and this spiritual community's willingness to deepen in consciousness!
Rev. Nickie Golden, Co-Minister
I love the depth of love and unconditional acceptance in this spiritual community - from the people to the principles. I am inspired to live into my 'full aliveness!'
Rev. Mindy Tucker, Co-Minister
What is Unity?
New to Unity?
Spiritual Leadership
Our History


text:
Welcome to the blog
I'm Ashley again, the girl behind the lens, this business, and this blog! You probably found yourself here for two reasons, you love my work and want to see more or you're just lost (let's hope its the first reason). I've already introduced myself on my home page so I won't do that here. This is where I am going to let you get to know me, ALL of me. Yes, the good, the bad and the ugly. I will share my life with you, my super awesome stories from weddings and sessions I've done and the "not so fun" educational content on running your own photography business.
My plan for this page is for you to hang with me (virtually) and step into this sweet little business of mine and truly see my passion and why I love what I do so much!
So grab a cup of coffee (or a Jack + Coke) and dig right in.


text:
Here is a selection of some of our favourite and most-read blogs out there:
I'm always commenting on how fast time flies these days, and this month is no exception - I can't believe that we're done with one-twelfth of 2009 already. January's been unexpectedly busy, with a couple of deadlines set for the end, plus another new site which cropped up and needed to be designed and built before the month was out.
Smart Tactics wanted a new design which was clean and to the point
The Power of Insight was the new one that slipped into the schedules in January, a service from one of our partners, Smart Tactics. The original site wasn't too bad, but a little outdated - and because it was built entirely in Flash, not really practical to update. Smart Tactics wanted a new design which was clean and to the point, and more importantly highlighted the three key sections of the website. They liked the transition effects that Flash provided in the original site, so I produced something similar using Mootools and some simple image transitions - the effect is pretty cool and works well.
The design took a while to polish until we were both satisfied, but it stitched together nicely in Joomla! and looks even better in the final, live site. I even got my hands dirty in Flash to modify the embedded video so that it fit seamlessly into it's very own module position...something I enjoy doing, but never seem to have the time to get too involved with unfortunately.
Next up is a project I've been working on for a few months now - White Rhino Event Solutions - a SOBI2-powered site which showcases different corporate event solutions. Given the awesome flexibility of SOBI2 and the customisation options, it was a perfect fit for what was needed...I love this component! Definitely one of my favourites anyway. Most of the site content is embedded in the directory, we even added some custom bits in there to forward to some custom enquiry forms, a "Bookmark this page" button, and a "tell a friend" feature. We also embedded the gallery with Shadowbox pop-ups into each listing - looks quite simple but there's quite a bit going on under the hood.
Once again the site feaures a custom-designed template created by us.
And finally, just yesterday I finished up work on OVS Direct sister-site OVS Trade - a car dealer listing site for the part-exchanged stock that the company deals with. Again, the site is using the rather excellent EZ Autos vehicle listing component, all running under the Joomla! 1.0 fork A8E, to give us that semantic, table-less core output that normal Joomla! simply cannot do.
So...here we go full-speed into the second month of this New Year, and with plenty of new and exciting projects coming up - looks like my break will need to wait...again!


text:
Guests will enter at GATE D, with entry permitted beginning at 4:15pm. Fenway will have two security staffers at the entrance who will be responsible for greeting guests, checking bags, etc. Those staffers will also assist in directing guests up to the event space/ CFMA registration area.
We have secured 35 parking spots at 73 BROOKLINE AVENUE LOT, located next to Boston Beer Works.
Please reference CFMA Reception to the parking attendant, and these will be available on a first come, first served basis.
We will be offering a private tour at 7:30PM to conclude the event. The tour will be 45 minutes and conclude at the GATE D entrance/exit, therefore all those that choose to take the tour will have to take all their belongings with them since the tour will not return to the event space once it departs.
William G. Gross Police CommissionerBoston Police Department
William G. Gross is the 42nd Police Commissioner of the City of Boston. He has served the people of Boston for 35 years. After joining the department in 1983 as a Boston Police Cadet, he graduated from the Boston Police Academy in 1985. He spent years as a patrol officer, patrolling the many neighborhoods of Boston. . He was promoted to the rank of Sergeant in 2004 and rated Sergeant-Detective in 2006. In 2008 he was appointed to the Command Staff as a Deputy Superintendent and promoted to the rank of Superintendent in 2012, assuming the role of Night Commander overseeing police services citywide. In January 2014, he was appointed by Mayor Martin J. Walsh and Police Commissioner William Evans to the position of Superintendent-in-Chief, the first African American Chief to hold the rank in the history of the Boston Police Department. Throughout his career he has cultivated and maintained a strong connection with the community. He often could be found on the front lines; interacting with community activists, grieving families, clergy, neighbors, even protesters; treating everyone with respect and dignity. He strongly believes that "if you want change, you have to be the change", a philosophy he models for the community and the members of the police department. He has been awarded numerous Departmental awards for bravery and meritorious service and several Governor's Citations and was named one of Boston's 100 Most Influential People of Color. In June 2018, , he was presented the Robert F. Kennedy "Embracing the Legacy" Award. This award recognizes those who work tirelessly to carry on the legacy of the late Senator by raising awareness and fighting against societal injustice and inequity that affect children and families. He also sits on the Advisory Boards for Boston Center for Youth and Families, the George Lewis Ruffin Society and the Special Olympics of Massachusetts. On August 6, 2018, William G. Gross was sworn in by Mayor Martin J. Walsh, again, breaking down barriers by becoming the first person of color to hold the Police Commissioner's position in the City of Boston. "I am honored and humbled to be sworn in as the Police Commissioner of the best police department in the country. Delivering and building on our community policing model is one of my main priorities. We will work collaboratively to reduce crime and violence in our neighborhoods while supporting and lifting up our youth."
Massachusetts Chapter
Tel: 781-828-8474 | Email: email@example.com


text:
Best Microwave Repair Service in Agarkar Nagar, Pune
- Doorstep repair within 90 mins
- Protection Against Damage Upto INR 10,000
- 30 day post-service guarantee
Need a Microwave technician for:
How it Works
Choose the service you need
We provide repairs and servicing.
Choose your time-slot
We service from 9am-9pm
Hassle-free service
Our professional will get in touch with you one hour before the service
Related Microwave Repair Professionals Services
Customers in Agarkar Nagar also booked
Nearby localities
Recent Customer Reviewsof Microwave Repair Professionals near Agarkar Nagar
Knowledgeable. Polite. Extremely professional. A pleasure to have him do my work.
Excellent service.
Excellent service by the professional.
Reviews received in last 365 days
Looking to hire professionals near Agarkar Nagar?
Tell us your requirements and get custom quotes with profiles within 24 hours from upto 5 interested professionals.
Are you a professional looking for customers?join now


text:
Search remains a potentially lucrative acquisition channel for sports betting operators, but the ever-changing Google landscape makes it one of the most challenging for marketers to get right. Which explains why a group of marketing and SEO specialists from sports betting and online casino operators could be found in a conference room at Google's London office on a cold, wet …Read More »
Tag Archives: Receptional
Jack Rose, Receptional: Tackling the Google test for sportsbook operators
Promoting a sportsbook via Google is an increasingly complex and competitive exercise, but the rewards for operators that get it right can be huge. SBC caught up with Jack Rose, Head of Sports & Gaming at digital marketing agency Receptional, to talk keywords, smart bidding and video advertising. Speaking ahead of the SBC Award-nominated agency's What's New in Search Marketing …Read More »


text:
As a Professional Services Engineer, you are an integral part of our engineering team. Your passion for providing exceptional customer service contributes to our world-class level of customer satisfaction. Working with PHEMI customers worldwide you communicate in an open, helpful and engaging tone with a focus on finding the right solution for them.
As part of the R&D team, you play an integral role in deploying extraordinary customer solutions by working collaboratively across functional teams to deliver customer solutions and resolve issues in a timely manner with high quality.
- Install and configure PHEMI product software at customer sites or within cloud environments
- Implement and maintain customer customizations to support their solution
- Provide technical support and training
- Advocate for the customer, proactively communicating requirements, issues and resolutions with both the customer and PHEMI teams
- Document customer deployments, maintaining a trouble-shooting and best-practice knowledge base
- Provide regular reports to customers and PHEMI teams on system status
- Coordinate response for customer privacy and security requirements (e.g., PIA, STRA)
- Work flexible work week including weekend coverage
- Work within an agile development environment, collaborating with multiple teams and stakeholders.
Required Skills & Abilities
- Excellent verbal and written communication skills
- Proficiency in Linux system installation and administration (Ubuntu preferred), virtual machines, and configuration
- Proficiency in security configuration for distributed system deployments
- Proficiency in distributed systems troubleshooting
- Proficiency in Java, Python programming, and Linux shell scripting
- Knowledge of SQL & No-SQL databases
- Excellent problem-solving skills
- Proficiency with cloud service deployments (e.g., AWS, Azure, OPI, Google Cloud)
Professional Qualifications & Experience
- BSc. Computer Science, related field or equivalent experience
- 5+ years in a professional service engineering or software development role demonstrating the required skills an abilities in Linux, Java, Python, and troubleshooting complex distributed systems
- Experience working with Accumulo and Hadoop is preferred
- Experience with large scale distributed systems is preferred (e.g., HPC and big data technologies)
- Experience with Security and Privacy compliance laws is favorable (i.e. GDPR)
Why you should join
We are on a roll! In November 2015 we were recognized with a Deloitte Technology Fast 50™ award: Companies to Watch; we closed a large financing round in 2015; we were selected as LifeScience BC's 2014 Emerging Company of the Year, the BC Technology Industry Association's Start-up of the Year, and were announced as one of the Ready to Rocket companies for 2014 and 2015.
If you like the energy of a fast-growing company and want to work in a technology company that changes how healthcare, and other industries, discover and drive value from their data, we want to hear from you.
Our leadership team has taken numerous early-stage companies to commercial success and our technology team is second to none. With decades of experience delivering amazing products across a wide variety of industries, we are applying our business experience and technical depth to some of the critical challenges facing enterprises today.
For more information visit https://www.phemi.com/ and follow us on Twitter. We look forward to hearing from you!
Great people. Great technology. Great opportunity.


text:
Federer and Nadal will battle it out on Centre Court on Friday in their first meeting at SW19 since the 2008 final. Tennis fans from all over the world are eagerly-anticipating the encounter between two greats of the modern era. BBC pundit Castle is likely to be …Read more
Andrew Castle reveals the pressure Roger Federer and Rafael Nadal Wimbledon tie causes
Federer and Nadal will battle it out on Centre Court on Friday in their first meeting at SW19 since the 2008 final Tennis fans from all over the world are eagerly-anticipating the encounter between two greats of the modern era BBC pundit Castle is likely
Read more
Roger Federer claims historic eighth Wimbledon title with straight sets win over emotional Marin Cilic
It was a memorable milestone for Roger Federer the last time a player retired in a Wimbledon final was back in 1911 Theres no let up from Federer as he continues to hammer Cilic according to Andrew Castle He brings up three set points
Read more
BBC commentator Andrew Castle in sexism row over Marcus Willis girlfriend
BBC commentator Andrew Castle sparked a new Wimbledon The young Brit set up a dream tie with Roger Federer who defeated Argentine player Guido Pella in his first game at Wimbledon But ultimately the power of the competitions seven-time winner
Read more
Australian Open day nine in Melbourne as it happened
In the mens draw Roger Federer and Stan Wawrinka have set up a dream all Australian Olympic swimmer Mack Horton who won gold in the 400m at the 2016 Rio Games revealed Rafael Nadal had to put up with more interference than most from fellow
Read more
Goodbye Andy Murray a human in the land of the Gods a testament to the power of dreams
Oh yes Andrew Castle purrs on the BBC commentary Centre Court whoops and gasps The year is 2017 the skies over Wimbledon are blue t a freak of technique like Roger Federer nor a freak of endurance like Rafa Nadal nor a freak of physics
Read more
Roger Federer and Rafael Nadal Castle reveals who may beat them at ATP World Tour finals
Castle is impressed fans worldwide Nadal finishes the year as the world No1 for the fourth time but Federer beat him on all four occasions they played during the year If the Nitto ATP Finals finish with a RogerRafa showdown that would
Read more


text:
American Holidays, Belfast City Blues Festival – Belfast 89FM
Terms and Conditions
Entry to this competition implies acceptance of these terms and conditions:
The Prize
2 Return economy flights Dublin to Minneapolis with Aer Lingus
4 Nights @ The Hyatt Regency by Mall of America (one standard room only, no meals included, based on 2 adults sharing)
2 Nickelodeon Universe® All-day wristbands
2 FlyOver America admission tickets (no meals included)
2 SEA LIFE® Aquarium admission tickets
2 Dutchman's Deck Adventure Course admission tickets
2 Moose Mountain Adventure Golf admission tickets
2 Rock of Ages Backlit mini golf admission tickets
2 VIP tickets to Paisley Park (the former recording studio and home of Prince)
1 $50 Hard Rock Café gift card
Mall of America VIP discount voucher book
Car hire for duration of the trip.
1. Competition open from June 17th 2019
2. Competition closes on June 28th 2019. The winner will be announced on the Belfast 89FM Facebook page, followed with a confirmation email from American Holidays.
3. Entrants must be over 25 years of age and resident in the Northern Ireland.
4. The Judge's decision is final and binding on entrants. No correspondence will be entered into.
5. Flights, Accommodation and extras are non-refundable, non-transferable, non-endorsable and hold no cash value.
6. Car hire includes standard compact car only, insurance provided on the standard cover. The winner will be required to pay extra insurance and sat nav if required. Petrol and tolls within the USA will be at winners own expense.
7. Prize must be used by 31 December 2019.
8. Booking must be made by 30 August 2019 and travel can be from that time up to 31 December 2019. Black out dates may apply and these may include bank holidays, peak travel dates and any major holidays within the USA.
9. Tickets must be used by the prize winner and a companion travelling named at the time of booking.
10. No changes will be permitted to the booking after it has been confirmed.
11. Prize Excludes: Personal expenses, excursions, travel insurance, transfers to/from hotel and airport, additional night's stay/upgrades/additional passengers/resorts fees & ESTA.
12. It is the prize winner's responsibility to ensure all passport & visas (if required) are valid for travel.
13. All bookings are bound by American Holidays Booking Terms & Conditions, available HERE
14. Entrants must consent to the disclosure of their name as a winner. The winner may be required to take part in future publicity.
15. Any entrant to the competition may obtain the name of the winner by emailing the American Holidays marketing team on firstname.lastname@example.com ref: Belfast 89FM – Belfast City Blues Festival
16. Customer data will not be used for marketing purposes, however may be shared with competition partners. A copy of the American Holidays data protection and privacy policy can be found HERE.
17. Competition entrants agree and accept these competition T&C's.
18. American Holidays' staff, their immediate families and their agents and any other person connected with the competition are not entitled to participate.
19. American Holidays will not accept liability for lost, stolen or damaged excursion passes or vouchers.


text:
As someone said previously, Can we please be able to honor an opponent, _please_? Since the first integration of Honor Update, I've seen quite more respectful and humble players across the other team and feeling like I should interact with that person more than 'hey, u're cool' in /all chat. Maybe was the one who solo-carried them w/o bragging about the whole time or the chill guy who even tho he lost his lane, he didn't start to blame anyone in /all for the mistakes committed. I've got nothing to say on the Orbs&Capsules atm, I'll just have to spend some time and see how I feel about them. Thank you & the other cool Riot members for your work! {{sticker:slayer-pantheon-thumbs}}
Thank you for the feedback and testing! Unfortunately, we aren't delivering Honoring opponents with this update, but we hear you.
Hi NeuroCat! I'm glad to see some changes to the honor system! Thank u! I like the new direction of this but i'm wondering about the Honor Orbs, what will it be contain? And will the honor capsules change? or will it still have the usual?
TL;DR - Orbs will generally contain key fragments and Blue Essence/Champ Shards. Capsules will generally contain an amped up amount of what's in orbs, plus a cosmetic item of some sort (ward skin, emote, exclusive champ skin). Higher level orbs/capsules will give you better stuff.
|Rioter Comments
|new Comments
|Rioter Comments
|new Comments
shouldn't "Hate Speech" and "Verbal Abuse" be under the same category? also I love how you removed "Unskilled Player" and added "Cheating"! This report system is a lot cleaner then the current one. great job! :D
Hate Speech specifically is referring to instances of racism, sexism and homophobia, which we have zero tolerance for. Verbal abuse can exist without including hate speech.
So when are we going to be able to report people in champ select? Really tired of people trolling because they didn't get their role, or because someone on the team played poorly last game.
Before we start considering what a champion select report experience would look like, we want to see how things shake out with the new champion select/draft mode. Hopefully, this should solve a lot of issues arising from role conflict.
Thank you! One thing though... Do you think you could group up similar report groups? My suggestion would be to list them in this order (from top to bottom): Leaving the game/AFK (having this one first makes the list look nicer since it doesn't have a description), Cheating, Negative attitude, Intentional feeding, Verbal abuse, Hate speech, and Offensive or inappropriate summoner name (leaving this one last also makes it nicer due to no description). This order keeps similar things next to each other (the four behavior categories and the three speech categories grouped together), making it easier to find the groups you need at a glance. Additionally, just as a small, grammatical nitpick- could you change the comma in the description box to a dash (-) or a semicolon (;)? The way it is right now is technically improper grammar (it's colloquial, so if that's what you're going for then it's fine).
The nitty gritty here is still work in progress. We intentionally separated hate speech and cheating from the other categories of "chat-related offenses" and "gameplay-related offenses" because we have zero tolerance for them. I'll look into the grammatical stuff :)
>With these upgrades, we're allowing up to 3 categories to be selected when reporting a player. I love you >In the future, players who falsely report others may face penalties. I love you alllllllll Question! The "unskilled player" report will be permanently removed, then? Also, any plans on more PBE-specific report stuff?
Unskilled player is gone! [Lyte made a good context comment here](https://www.reddit.com/r/leagueoflegends/comments/3owsvr/updated_reports_coming_to_the_pbe/cw18hqx)
|Rioter Comments
|new Comments
|Rioter Comments
|new Comments
Level 30 (PBE)
Lifetime Upvotes


text:
Irrespective of whether you've got just a tiny laundry storeroom or small laundry room, your laundry area can be equally useful and beautiful. Indeed, a tiny laundry room could be a dream laundry room with all the right agency conclusions. This is a huge change, moving out of heaps of laundry equally pristine and cluttered with clean about the casual accommodation brief bushels and filthy around the floor and in taller hamper crates.
The first thing was expelling the glowing light. The light gave a real cerebral pain, and that means you may required that from this room as an issue of first importance since You knew you'd devote a fantastic deal of hours in that room carrying a shot at it. Changed into a flushmont. I couldn't trust how easy it had been, and was twisting myself hadn't shifted it earlier. It left two small openings in the roofing, however that has been efficiently fixed and painted.
On the off probability that I appear short on space about the ledges, I will use the racks for contained clean dropped clothes impermanent capacity zone till the stage once the children escape. I really do the falling, and the kids place everything endlessly. Rustic style hand generated sign is that the perfect stylistic motif for the own laundry room. Exceptionally unique unique signal that includes a rustic style for it. Between the organizing, drying, washing, and falling, laundry may occasionally feel like a perpetual undertaking so sprucing up this job room is not at the maximum stage of this program to your day for a big part of us.
Irrespective of whether you do not reside on this bovine homestead you normally envisioned, you can affect your laundry to room your provincial escape using a rustic tiled floor, comfy stylistic design, and a metallic sink which cries enchanting state home. Dreams do work out as anticipated. Say farewell to a dull, bothering laundry room of and hello to a sharp and charming new asylum with those 80 reassuring traps. You might even wind up making motives to do laundry. Consider the best way to use your laundry room, what ought to be put away in it, what types you dread, and snare your laundry room out thus doing laundry is a dream, not an errand.
image source : pinterest.com


text:
4th Floor, Salisbury House, Finsbury Circus, London. EC2M 5QQ. United Kingdom
4net Technologies
3 Scholar Green Road, Cobra Court, Manchester. M32 0TR. United Kingdom
Altitude Software
1210 Parkview Arlington Business Park, Theale, Reading, Berkshire RG7 4TY. United Kingdom
Britannic Technologies
Britannic House, Merrow Business Park, Guildford, Surrey. GU4 7AW. United Kingdom
Business Systems
462 London Road, Isleworth, Middlesex. TW7 4ED. United Kingdom
Content Guru
Radius Court, Eastern Road, Bracknell, Berkshire. RG12 2UP. United Kingdom
Spectrum House, Beehive Ring Road, London Gatwick Airport, West Sussex, RH6 0LG. United Kingdom
Foehn Ltd
Goodwin House, 5 Union Court, Richmond, Surrey. TW9 1AA. United Kingdom
IFS Customer Engagement
Artisan, Hillbottom Road, High Wycombe, Bucks. HP12 4HJ. United Kingdom
Netcall Technology Ltd
Peoplebuilding Estate, Maylands Avenue, Hemel Hempstead. HP2 4NW. United Kingdom
Noble Systems
11, Commerce Way, Westinghouse Road, Manchester. M17 1HW United Kingdom
Suites 45-47 The Hop Exchange, 24 Southwark Street, London, SE1 1TY United Kingdom
PCI Pal
7 Gamma Terrace, Ipswich, IP4 4JA. United Kingdom
22 Tudor Street, Blackfriars, London EC4Y 0AY. United Kingdom
Sabio Group
12th Floor, 110 Southwark Street, London, SE1 0SU. United Kingdom
Abbey House, 1650 Arlington Business Park, Theale, Reading RG7 4SA. United Kingdom
Ealing Studios, Ealing Green, London W5 5EP. United Kingdom


text:
3 LED Plastic Flashlight with MagnetItem# Q57050
at ea.
Shipping Included
Printing Included
Setup Included
Need it sooner?
Everything You Product features, size, materials - whatever you wanted to know
Need to Know
about this product. Read on to see if it's a perfect promo match!
Product Overview
There are plenty of everyday situations where you might find yourself suddenly needing a flashlight. Maybe your computer begins acting strangely and you need to check under your desk to see which wire in the tangle has come loose. Maybe your car breaks down on an unlit stretch of highway and you need to check under the hood. Maybe the power suddenly goes out in your building and you need to walk down a darkened stairway. Whatever the case, you want a flashlight that's immediately available, something you can attach to a key ring or purse strap, then forget about until it's needed.
The 3 LED Plastic Flashlight with Magnet from Quality Logo Products® features
- 3 LED lights (hence the name) that activate when the flashlight is pulled from the magnetic cap
- a carabiner clip for easy attachment
- 2 replaceable batteries
- your business logo or advertising slogan prominently displayed
The 3 LED Plastic Flashlight with Magnet makes a great gift for clients, vendors, co-workers, or anyone else in your business circle, because we all get caught in the dark once in a while. Order yours today.See All
How We Add There is a lot that goes into making sure your logo looks
Your Logo
absolutely perfect. Here is only the important stuff.
Did You Know - we send a complimentary proof with EVERY order?
1.5" W x 0.5" H Template
Ink Imprint
What color(s) can I make my logo?
We Need
Your Help! Have you ordered this item or seen it in the wild? If so, could you do everyone a solid and share your thoughts? Please? Pretty please?
As Low As $2.42 ea.
As Low As $1.96 ea.
As Low As $0.65 ea.
As Low As $1.63 ea.
As Low As $2.58 ea.
As Low As $1.63 ea.
As Low As $0.80 ea.
#10 Best Seller
As Low As $1.84 ea.
As Low As $2.19 ea.
As Low As $0.94 ea.
As Low As $0.97 ea.
As Low As $1.69 ea.