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The Black Creek Village Library Board of Trustees is a board made up of citizens of the Village of Black Creek and the Town of Black Creek and is primarily appointed by the Village President with one School District Representative appointed by the Superintendent of Schools.
The Library Board's standing meeting date is the first Tuesday of the month at 6:00pm.
Current Library Board Trustees:
- Jenni Court
- Brandi Schomisch
- Susan Anschutz
- Sandy Heiden
- Carolyn Grunwaldt
Library Board Meeting Agendas:
Library Board Meeting Minutes:

subset: commoncrawl


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For forums, blogs and more please visit our
Developer Tools Community.
By: Tim DelChiaro
Abstract: Learn about language control structures including begin, end, if, case, boolean expressions, and loops
This information comes from The Oxygene Language Wiki. See the links at the bottom of the article to navigate to additional content on the wiki and view any updates to this information.
Control structures are a very important part of every programming language. They control the flow of your program and make it possible to execute one part of code more than once or "decide" between different parts of code.
Before we can talk about such structures, it has to be clear what "parts of code" are. How does one define a part? Well, that's relatively simple: You define its beginning using the begin keyword and its end with the end keyword. You've already seen both, e.g. in the code that's executed when the button is clicked. Everything that is executed is one "block", which is the correct word for "part of code".
Why is there no semicolon after begin? Because begin isn't a command, but marks the start of a command! The end of the command is the endkeyword and there's your semicolon then ;-) That's important: The begin-end-block is one command in Delphi Prism!
We want to extend the mini calculator by adding another feature: dividing numbers. Add a new button "btDivide" with the text "Divide" to the form. Double click on it to get to the event handler. The code is almost the same as for the addition. Copy it into the new event handler and replace the "+" by "/". This is the division operator. This is an integer division, so 4 / 3 is 1 and not 1.33.
Run the program, input "5" as first number and "0" as second number. When clicking "Divide" the program will throw an exception. Those are thrown every time the program does something that shouldn't be done and the program can't continue without handling this exception. Most of these "An unexpected error occured" messages you get by some programs are unhandled exceptions. This time you tried to divide by zero which isn't defined.
The best way to deal with exceptions is to make sure they don't occur. So we have to check if the second number is zero and if it is, we'll show a "nice" error messgae in the result textbox.
This looks (for the moment) like this:
var firstNumber := Integer.Parse(tbFirstNumber.Text);
var secondNumber := Integer.Parse(tbSecondNumber.Text);
if secondNumber = 0 then
tbResult.Text := 'Division by Zero';
if secondNumber <> 0 then
var resultNumber := firstNumber / secondNumber;
tbResult.Text := resultNumber.ToString;
You know the first two lines, but the next line is something new, it contains the 'if' statement. Its structure is:
if {condition} then
So, in the first 'if' statement, the condition is that secondNumber equals zero. The command is to display "Divide by Zero" in the result textbox. By the way, this is one of defining strings in your source code: Start it with an apostrophe, end it the same way and put your text in between.
The second 'if' statement is similar. The condition is that the second number is not zero. The command is a begin-end-block which, as we learned earlier, is one command.
In the next section we'll take a look at what conditions can look like.
In this section there's another keyword to introduce: else. We can write the previous code a little bit shorter and much better to read using this keyword:
if secondNumber = 0 then
tbResult.Text := 'Division by Zero'
else begin
var resultNumber := firstNumber / secondNumber;
tbResult.Text := resultNumber.ToString;
This source code does exactly the same thing as the previous source code, because the first condition is the exact negation of the second condition. The first branch ("if-branch") is only executed if the condition is true, otherwise the second branch ("else-branch") is executed.
Perhaps you'll notice that there's no semicolon behind the line in the if-branch. That's no mistake and it's no exception to the rule that every command has to be separated by a semicolon. The command we're dealing with here is the if-command and this is not finished there: the else-branch is part of the if-command, too, so the semicolon has to be placed after the else-branch.
Of course you can nest if-commands into each other:
if {condition} then
if {condition} then
There's no problem here, but it can get unclear if you add an else-branch:
if {condition} then
if {condition} then
That's wrong! The indentation suggests that the else-branch belongs to the first if-statement, but in fact it does belong to the second if-statement. The else-branch always belongs the next inner if-branch. Therefore, the correct indentation is:
if {condition} then
if {condition} then
If you want to have an else-branch for the first if-statement, you have to put the second if-statement into an begin-else-block.
if {condition} then
if {condition} then
Note that the position of the semicolons has changed now, too.
The condition of an if-statement is a boolean value. A boolean value can be true or false. .NET offers the variable type Boolean for that.
The check for equality of two numbers has a boolean result and therefore can be used as condition in an if-statement. Other comparisons could be "greater than" (>) or "less than" (<). The statement "I have more money in my purse than you" can be only true or false. I can define the amount of money in my purse as "number1" and the amount of money in your purse as "number2". The statement can be then written as number1 > number2.
Boolean expression (also called boolean operations, named after George Boole) are the composition of boolean values and have a boolean value as result. You can use them to define more complex conditions:
newBoolean := boolean1 and boolean2;
newBoolean := boolean1 or boolean2;
newBoolean := not boolean1;
newBoolean := boolean1 xor boolean2;
The first two expressions should be self-explanatory. In the first expression newBoolean is only true if boolean1 is true and boolean2 is true. In the second expression newBoolean is only true if boolean1 is true or boolean2 is true or both are true.
The third one is the negation, newBoolean is true if boolean1 is and vice versa.
The fourth expression is called "exclusive or". In colloquial language you'd call it "either ... or". newBoolean is true if either boolean1 or boolean2 is true, but not both!
Because every of these expressions results in a boolean, you can create new compositions with them:
boolean1 and boolean2 or boolean3
This source code is valid and can be evaluated unambiguously, but it's not good to read. You have to think about which part of the expression will be evaluated first. I recommend using braces even if they are not needed:
(boolean1 and boolean2) or boolean3
Delphi Prism would've evaluated the expression like that in the first place. It uses something called operator precedence, which you can imagine as the "strength of binding" of an operator. Or a little bit easier: How "important" the operator is ;-). You've learned in school that multiplication and division have a higher precedence than addition and subtraction.
The precedence of boolean operators is:
* not
* and
* or
* xor
Operators of same precedence are evaluated from the left to the right.
You can make use of this fact: Delphi Prism evaluates a boolean expression only until its value is known. The rest of the expression won't be evaluated if it can't change the value of the expression anymore. For example if you have an expression A and B and A is already false, B won't be taken into account, because the complete expression must be false! This is called short-circuit evaluation.
So, how can you make use of this? Write the expressions that can be evaluated fastest to the left. If A and B are both functions, then you would choose Ato be the one that is evaluated fast and B the slow one. If the "fast" method is false, the "slow" method won't be evaluated and the whole expression is evaluated faster.
But you have to make sure that the method potentially not evaluated doesn't have side effects. If this method must be evaluated, because it does more than only return a boolean value, you shouldn't use it directly in a boolean expression but evaluate it seperately and store its result in a variable which you then use in the expression.
In some cases, there's a better way to bring branches into your program than using an if expression. Let's take a look at this source code:
if number1 = 0 then
if number1 = 1 then
if number1 = 2 then
That doesn't look very nice. The case command will make it look much better:
case number1 of
0: command1;
1: command2;
2: command1;
I think it's clear how this works. It's like a table of values and command: you look up the value of number1 in the table to find the appropriate command and then execute it.
The above code can be written even shorter:
case number1 of
0,2 : command1;
1: command2;
If there's a default command you want to have executed if none of the values match, the case command offers an else branch:
case number1 of
0,2 : command1;
1: command2;
The case command works with every type you like, for example strings.
Loops allow the programmer to repeatedly execute parts of code. The number of times the code is executed needn't be known when the program is written, but can vary during runtime. There are several ways to terminate a loop, like giving a specific number of iterations or a boolean "termination condition". There's more to know about loops in Delphi Prism than we will see in this chapter, but it's enough for the start.
To demonstrate the 'for' loop, we will extend the mini calculator with a new feature: Calculation of a number's factorial. For example the factorial of 5 is written as 5! and can be calculated as 5*4*3*2*1. It's often used in probability calculations.
Please add a button "btFactorial" to the mini calculator and then switch to its click event by double-clicking on it. This time we'll only need firstNumber, because we only want the factorial of the first number in the textbox. In addition the resultNumber has to be initialized with the value 1:
var firstNumber := Integer.Parse(tbFirstNumber.Text);
var resultNumber := 1;
Now we want to build the loop that calculates the factorial, which means that resultNumber has to be multiplied first by 2, then by 3 and so on until we reach firstNumber. That looks like this:
for i : Integer := 2 to firstNumber do
resultNumber := resultNumber * i;
Let's analyze what we see here. First thing is the i : Integer. This is the loop counter or loop variable. A for loop in Delphi Prism always defines an own variable for this and never uses a variable declared outside the loop.
Its value will change from itertation to iteration. The range of values is defined by the second part of the for loop's header: 2 to firstNumber. For each number the body (resultNumber := ...) of the loop will be executed with i having the according value.
What's happing in the loop gets much clearer, if we "step through it". Before the body is executed the first time, the resultNumber is 1. Then a new value is assigned to resultNumber: the product of resultNumber's old value (= 1) and the first value of i (= 2). Therefore the new value of resultNumber is 2.
You can write down the steps of the loop like this:
resultNumber := 1 * 2; //resultNumber is 1, i is 2
resultNumber := 2 * 3; //resultNumber is 1*2 = 2, i is 3
resultNumber := 6 * 4; //resultNumber is 2*3 = 6, i is 4
resultNumber := 24 * 5; //resultNumber is 6*4 = 24, i is 5
By the way: The gray parts in the source code are comments, which will be ignored by the Delphi Prism compiler and are only notes for the programmer.
The loop in this sample does only count up and only by one per iteration. You can modify both. By replacing the to with downto the loop will count down. Of course the loop variable's initial value has to be greater than the end value, otherwise the loop wouldn't ever execute its body.
To change the value by which the loop variable is incremented or decremented per iteration, you can specify a step size:
for i : Integer := 10 downto 2 step 2 do
In this case i will have the values 10,8,6,4,2.
(To complete the extension of the calculator, you'll have to add an additional line to the method to display the result. You should know how that has to look. ;-))
In many cases you can't predetermine how often the loop body has to be executed and therefore you can't use a 'for' loop. In that case you can use a loop with a boolean termination condition. For example a 'repeat-until' loop.
The name of the loop explains pretty well what it does. It repeats executing the body until a condition (a boolean expression) becomes true. The calculation of the factorial can be written like this:
var firstNumber := Integer.Parse(tbFirstNumber.Text);
var resultNumber := 1;
var i := 2;
resultNumber := resultNumber * i;
i := i + 1;
until i > firstNumber;
As you can see, we introduced a variable that we use as loop variable and increment manually in every iteration. You are not bound to a loop variable in repeat-until loops, it's just in this sample. The body is executed until i is greater than firstNumber.
An important thing about the repeat-until loop is that the body is executed at least once, because the condition is checked after the body was executed the first time ("post-test loop"). Also note, that you don't need begin and end to have a body with more than one line, the body is delimited by repeatand until.
The 'while-do' loop is very similar to the repeat-until loop. The previous source code looks like this when using a while-do loop:
var firstNumber := Integer.Parse(tbFirstNumber.Text);
var resultNumber := 1;
var i := 2;
while i <= firstNumber do
resultNumber := resultNumber * i;
i := i + 1;
The differences between while-do and repeat-until are:
It happens that you want to completely cancel a loop or just skip the current step of a loop and directly continue with the next one. In the first case, this can be done with the break command, in the second case with the continue command.
For example:
for i : Integer := 0 to 10 do
if i = 5 then
if i = 8 then
The first if-command will make the loop skip the rest of the method body and directly continue with i = 6, if i equals five. The second if-command will cancel the loop completely, if i equals eight. The loop will therefore display: 0,1,2,3,4,6,7.
Delphi Prism offers another kind of loop: A loop command, which in fact is an infinite loop which only stops if you call break. You can use it like this:
var i := -1;
loop begin
i := i + 1;
if i = 5 then
if i = 8 then
if i = 10 then
Of course the third if-statement is useless, but needed for this loop to be equivalent to the for-loop above.
The Prism Primer: Part 1 – Part 2 – Part 3 – Part 4 – Part 5 – Part 6 – Part 7 – Part 8 – Part 9
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text:
No chemical substance, mixture or article containing a chemical substance or mixture may be imported into the customs territory of the United States if it fails to comply with any TSCA rule or otherwise violates TSCA, a requirement under Section 13 of TSCA and 19 CFR 12.118 through 12.127.
Where are the Regulations for importing Chemical Substances?
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text:
Corbett plan for Philly schools falls short of $180 million, relies mostly on city dollars
by Dale Mezzacappa and Holly Otterbein for the Notebook and NewsWorks
Hours before the deadline for passing the state budget, Gov. Corbett announced a plan to help the Philadelphia School District out of its fiscal crisis that relies mostly on dollars from the city, will require more borrowing, and contributes an additional $45 million of one-time state money.
The budget passed the Pennsylvania House and Senate, and Corbett signed it Sunday night. A portion of the funds also come with strings attached.
With the fiscal year ending and more than 3,800 District layoffs scheduled to take effect Monday, Corbett outlined a plan Sunday afternoon that he said would raise an additional $140 million for the city schools, short of the $180 million the District asked for from the city and the state. And one chunk of Corbett's $140 million package was money that was in his original spending plan and already factored into the District's budget.
It was unclear Sunday how many layoffs or other cuts would be averted under the plan.
Sales tax to hang around
Corbett proposed to let Philadelphia extend its 1 percent sales tax past its scheduled expiration in 2014 and dedicate that revenue for schools. Because that money is used by the city for this fiscal year, the governor's plan would let the School District borrow $50 million against the expected increase to close its 2013 budget gap. The sales tax extension was approved by the Senate on Sunday night, and a GOP House spokesman said members were on board and would approve it Monday.
The governor's plan also would give Philadelphia $45 million from a pot of money that the federal government had wanted, but has now apparently forgiven, from the state for past Health and Human Services overpayments. The Senate authorized this one-shot infusion of dollars Sunday night, and the House will vote on it Monday. House GOP members also support that, according to a spokesman.
The Senate attached conditions to the $45 million and the sales tax extension, requiring that the state secretary of education determine that the District has enacted "reforms that will provide for the district's fiscal stability, education improvement and operational control." The Senate approved that language, but some Philadelphia House Democrats are against it, concerned that it is anti-union.
Philadelphia Senate Democrats, though, did not oppose it.
"Right now, we feel comfortable with it," said Sen. Vincent Hughes (D-Philadelphia). "Everything we have in place allows for free and fair bargaining."
Hunt for back taxes stressed
Corbett's plan counts on Philadelphia doing a better job of collecting its taxes to raise $30 million more. The legislature is considering several bills to help do that, including one that would allow Philadelphia to put liens on properties in other counties owned by delinquent city taxpayers. Those bills were not voted on and do not appear to be on the immediate agenda. Mayor Nutter and City Council were projecting the slightly lower figure of $28 million in new revenue from cracking down on tax delinquency.
The final chunk of Corbett's package comes from a $122.5 million increase in state basic education funding, which for Philadelphia will rise 1.6 percent to $984 million. While Corbett said the increase amounted to $15 million in new dollars, it is only a $2 million increase over his February budget proposal, on which the District's budget is based. Local officials confirmed that the increase was mostly money already counted on by the District.
The total increase for Philadelphia in state education aid is about $30 million, but that includes appropriations for special education, transportation, accountability block grants and other funds the District was counting on.
The bitter taste of half a loaf
Philadelphia officials and some education advocates were clearly disappointed after their months of lobbying and following the playbook of adopting an austerity budget, closing schools, and declaring they had to "live within our means."
"The plan puts only $45 million of one-time state money into the schools," said one person close to the talks. "That's it. The other money is our sales tax and our delinquent tax collection."
School District officials did not return messages seeking a reaction.
The package would add up to $127 million in additional revenue — $53 million short of what the District said it needed from the city and state to avert a "doomsday" budget that would see schools open in September with little beyond a minimal number of teachers and a principal.
As District and city officials lobbied frantically over the last several weeks for a deal, Harrisburg was decidedly cool to most ideas. A plan that would have allowed Philadelphia to raise some $45 million this year through a $2-a-pack-cigarette tax — already passed by City Council — fell off the table at the last minute due to opposition from anti-tax Republicans in the House.
"I think it's terrible," said Susan Gobreski of EdVotersPA, which advocates for stable, recurring education funding. "What the state should be doing is enacting a fair funding formula instead of hamstringing districts. They're going out of their way to avoid providing adequate funding. It's blatant."
Democratic lawmakers also said the budget did not include enough state funding for Philly's schools.
"These are not new dollars in any significant fashion, new recurring dollars, that are coming from the state," Hughes said. "That is the big problem in this whole conversation."
Pennsylvania is one of only a handful of states that does not drive out new school aid each year according to a predictable formula based on the needs of districts, measuring such factors as tax base, tax effort, poverty rate, enrollment and student needs.
Gobreski pointed out that requiring the District to borrow against the sales tax to plug this year's $304 million shortfall will incur additional debt service payments. The District borrowed $300 million to make ends meet last year and now spends more than 10 percent of its operating budget, some $280 million, on debt service. Members of the School Reform Commission said they could not afford any more borrowing.
"That's money that should go into classrooms," she said.
Impact on teachers vague
The contingencies on the money do not specify any changes in the teachers' contract, particularly in seniority rules, that some education groups had urged as conditions for more funding. On the other hand, the language is vague enough to give the secretary of education power to judge what is reform and what isn't, putting pressure on the negotiations.
The District is seeking $133 million in labor concessions, most of it from the Philadelphia Federation of Teachers, to plug the balance of the $304 million shortfall. The PFT contract expires in August.
"This budget once again places education as our highest priority, accounting for 41 cents of every state dollar," Corbett said.


text:
Course Details
|8.5 hours
|License Options:
|Single Seat (90 days access)
Multi-seat (1 year access)
Consignors ship dangerous goods while consignees receive the dangerous goods. The Transportation of Dangerous Goods (TDG) Act and Regulations require both the consignor and consignee to be adequately trained and hold a TDG Certificate of Training for their work. The six modules of this course provide a detailed description of the parts of the TDG Act and Regulations that consignors and consignees must know. This includes classification, documentation, safety marks, means of containment, and emergency response.
Examples and quizzes reinforce learning and each module has a self-assessment to test understanding of the material.
A record of completion is provided by CCOHS upon successful completion of the final exam. A formal TDG Certificate of Training is issued by the employer when they determine their employee has a sound knowledge of all the topics and has received workplace specific training that directly relate to their duties with dangerous goods. The course was developed by CCOHS.
Topics include six modules:
- Overview: Provides an introduction and overview of the Transportation of Dangerous Goods (TDG) Act and Regulations. Includes information on training, classification, documentation, safety marks, means of containment, and emergencies.
- Classification of Dangerous Goods: Describes how dangerous goods are classified under the TDG Act and Regulations. Provides information on the nine hazard classes, and the relationship of TDG classes to shipping requirements and safety marks.
- Documentation of Dangerous Goods: Explains the purpose of documentation, the required information elements for shipping documents, and the requirements for consignors, carriers and consignees. The information is based on the requirements in the Transportation of Dangerous Goods (TDG) Act and Regulations.
- Safety Marks: Explains the types of safety marks, their purpose, and their requirements under the TDG Act and Regulations. Includes information on when and how the safety marks must be displayed, and when they can be removed or replaced.
- Means of Containment: Describes the various kinds of means of containment (such as drums and tanks) for dangerous goods under the TDG Act and Regulations. Includes information on the UN Packaging system and other standards for means of containment, certification safety marks, and other requirements such as handling and storage of the means of containment.
- Emergency Response: Describes the various types of dangerous occurrences and the requirements for reporting and responding to leaks and spills under the TDG Act and Regulations. Includes information on the use of the Emergency Response Guidebook, and the Emergency Response Assistance Plans (ERAPs).
Upon completion of this course you will be able to:
- Apply and understand the purpose of the TDG Act and Regulations
- List and understand your responsibilities as a consignor and consignee under the TDG Act and Regulations
- Describe the requirements and process for classifying dangerous goods and applying the appropriate labels and other safety marks to means of containment
- Know the requirements for shipping documents as they apply to consignors and consignees
- Know how to use standards and technical specifications to select appropriate means of containment for dangerous goods
- Describe the requirements for preparing, receiving, handling and storing means of containment
- Understand and fulfill your obligations in the event of an emergency, including reporting
Average time to complete this course is about 8.5 hours.
This course includes the SOR/2017-253 TDG regulatory amendment.
The course reflects Amendment 6 (February 2008) to the TDG Regulations, as well as Amendment 8 (June 2009) to the Transportation of Dangerous Goods Act, 1992.
Target Audience
This course is recommended for employees who work for shippers and receivers and perform duties relating to TDG and/or will be handling dangerous goods.
Guidelines for Training Criteria:
Transport Canada has prepared guidelines to help understand the training requirements in Part 6 of the Transportation of Dangerous Goods Regulations. For further information on the guidelines, see https://www.tc.gc.ca/eng/tdg/publications-cladvisory-advol1enew-267.htm.
This comprehensive e-course covers the topics listed in paragraphs (a) to (k) of the Section 6.2 of the TDG regulations.
The course does not cover the 6.2(l) ICAO and 6.2(m) IMDG training requirements.
Note: In addition to taking this course, workplace specific training for the type of substance handled and type of equipment used must be provided by the employer.
CCOHS offers three other TDG courses to meet your specific needs:
- Transportation of Dangerous Goods: A complete 8-module course designed for managers, supervisors, TDG co-ordinators, and those who have responsibilities for determining the training requirements for employees who will be handling dangerous goods. This 8 module course is optional for workers, employees and others who need to know about and perform duties relating to TDG.
- TDG: An Overview: Designed for managers and supervisors, employees and others who need to know about TDG, but are not responsible for TDG activities.
- TDG for Carriers: Intended for employees who transport dangerous goods, which may include loading and unloading shipments.
Prior technical knowledge of the transportation of dangerous goods system is not a requirement. However, familiarity with warehousing, shipping and receiving are helpful.
This course is delivered as an on-line e-learning course. All you need is a computer, access to the Internet - and you are ready to go! This e-learning course is designed to help you learn at your own pace and in your own environment at your own convenience.
Review Process
CCOHS courses are unique in that they are developed by subject specialists in the field, and reviewed by representatives from labour, employers and government to ensure the content and approach are unbiased and credible.
VuBiz Partnership
We partnered with Vubiz - an international leader in e-learning development - to create this e-course.
Vubiz offers other related e-learning courses that may also be of interest to you. Read about them in the Vubiz Catalogue of e-learning courses.


text: bumblebee 4 Posted April 14, 2013 (edited) Make : HONDA CBR900RR (FIREBLADE)Kilometres : 93947Price : $3,500Condition : UsedRegretful sale. This bike has been serviced every 5000kms since i purchased it 5years ago has been used as a daily ride with the occasional weekend ride. It will be supplied with a rear wheel stand. A new battery has just been fitted. Will be sold with rwc and rego. All reasonable offers considered. Edited November 12, 2013 by bumblebee Share this post Link to post Share on other sites


text: Hey guys. So, yeah, apparently my vow to write a blog post every week went out the window this month. We've just been SO busy lately with boat projects and planning a potential move to the Puget Sound, on top of our normal jobs, that I haven't taken the time to sit down and update … Continue reading Should We Take the Leap?


text:
By Tim Graham | July 29, 2009 11:36 AM EDT
To see how public radio talk-show hosts in every college town pick up Bill Moyers talking points off PBS like manna falling from Manhattan, there's this paragraph that appeared on ProfNet, a radio-booking service for political experts, from a Jim Lynch of WUSB 90.1 in Stony Brook, New York:
I'm seeking interviews with individuals with expertise on the increasing call of hate radio and television programs to "kill liberals" -- from the Kansas killing of a physician performing legal women's health services, to the church killings at liberal UU congregation in Tennessee, to the threats against Michael Moore and others. This is for "Everything is Broken," which airs Tuesdays at 1 p.m. This will be conversational and non-confrontational; no call-ins from listeners. Must be available for 30+ minutes. Contact: Jim Lynch [e-mail.]Notice the taxpayer-subsidized broadcasting modus operandi: we'll be charging conservatives with killing liberals, but it will be "non-confrontational; no call-ins from listeners." That's also just like Moyers. How much does the Jim-Lynching of conservatives match the Moyers talking points of Friday night? Let's count the ways. 1. Conservatives Killing "Women's Health" Providers.
MOYERS: In demonizing George Tiller, Randall Terry had help from the star of Fox News, Bill O'Reilly. For years, O'Reilly denounced the doctor as someone who would "kill a baby...for no reason whatsoever other than the mother has a pain in her foot." That wasn't true, of course, but 24 times altogether, O'Reilly denounced Tiller as a 'baby killer.'2. Conservatives Killing Unitarians in Tennessee.
MOYERS: As news spread of Dr. Tiller's assassination, and more details emerged, I thought back to what happened in Knoxville, Tennessee, on July 27, 2008, one year ago this coming Monday.3. Talk of Killing Michael Moore.
GLENN BECK, soundbite used by Moyers:I'm thinking about killing Michael Moore and I'm wondering if I could kill him myself, or if I would need to hire somebody to do it. No, I think I could. I think he could be looking me in the eye, you know, and I could just be choking the life out of him. Is this wrong?As he borrowed this 2005 soundbite from Hillary Incorporated, Moyers left out what Beck said next, which drained some of the "kill liberals" vibe:
I stopped wearing my What Would Jesus -- band -- Do, and I've lost all sense of right and wrong now. I used to be able to say, "Yeah, I'd kill Michael Moore," and then I'd see the little band: What Would Jesus Do? And then I'd realize, "Oh, you wouldn't kill Michael Moore. Or at least you wouldn't choke him to death." And you know, well, I'm not sure.
Radio hosts shouldn't even joke about killing liberals, since it risks them being compared to serious policy analysts like Alec Baldwin ("I gather up the body of the world's most notorious terrorist and hurl it over the balcony. Then, in the final stroke of luck, bin Laden lands on Dick Cheney." ).


text:
It's not that the upcoming title from Sidhe production studio is just like Geometry Wars or its sequel, but it shares many of the same qualities that that make the aforementioned title so enjoyable. Such as, clean game design, addictive gameplay, engrossing music, and fun.
While Geometry Wars is an updated take on the idea of the classic shooter, Shatter is the latest iteration on the Breakout, Arkanoid style of gaming. Using the mechanic of moving a panel back and forth to reflect a ball towards bricks that need to be broken is the idea, but Shatter one-ups that simple concept tenfold.
As you can see, the graphics of Shatter look pretty sweet, but what you can't see is how complex the game's mechanics really are. Bouncing the ball to shatter the bricks is just the beginning as Sidhe has also added the ability to to attract or repel the ball from your panel (or ship, if you will).
This ability to attract or repel, or "suck and blow" as I was told, creates a different set of physics than just the old school way of managing the angles as you try and clear levels of the bricks. There's also ways to create power-ups by collecting the shards of the shattered bricks an repelling them, or just by chaining successful hits and upping your power. Power-ups also play a part in the boss fights that occur at the end of each zone, and each of them are utilized differently creating a original experience throughout every encounter. Along with all that goodness, Shatter also has a custom made soundtrack by one of New Zealand's premier deejays to complete the experience.
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text:
Posted in Texas September 03, 2015
Here Are 12 Things You'll Never Catch Anyone From Texas Doing
Texans are a unique bunch of people, and we have a certain way of life here that simply makes sense to us. Of course, not everyone adheres to the same lifestyle, but there are a few key things that Texans just don't do under any conditions. See if any of these fit you!
What else do Texans not do under any circumstances? Tell us in the comments!


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Novel intravaginal ring shows promise in HIV prevention
A new 90-day intravaginal ring has been developed—that for the first time—enables the long-lasting vaginal delivery of tenofovir (TFV), the only topical prophylactic shown to be effective at reducing the sexual transmission of human immunodeficiency virus (HIV) when formulated in a short-lasting gel. This research is being presented at the 2012 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in Chicago, Ill., Oct. 14 – 18.
Lead researcher Patrick Kiser and colleagues from the University of Utah, in collaboration with CONRAD, a leading reproductive health research organization, created a novel reservoir ring composed in part of plastic tubing that absorbs water when placed in the body. Conventional ring technology, developed in the 1970s, is inadequate in delivering water-soluble drugs such as TFV. This new design allows for large quantities of TFV to be delivered for up to 90 days, at doses expected to prevent HIV infection.
"We anticipate that this next-generation ring will be able to release a spectrum of drugs that currently cannot be delivered due to limitations of standard technology," said Kiser, who led development of the ring at the University of Utah. "This ring is a breakthrough design because it is highly adaptable to almost any drug; the amount of drug delivered each day is the same and the release rate can be modified easily if needed."
Kiser's research group shows that the vaginal concentration of TFV in sheep using the new ring is similar to or exceeds that of a short-lasting TFV vaginal gel that was proven to be clinically effective at reducing the risk of HIV acquisition in women. This ring can also be readily modified to deliver an anti-HIV agent and a contraceptive at the same time, making it a multi-purpose prevention technology. Work is in progress to do just that, as the group has recently developed a ring to co-deliver TFV and the hormonal contraceptive levonorgestrel (LNG).
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chadavan necessitava di un nuovo design di t-shirt e ha lanciato un contest su 99designs.
È stato scelto un vincitore tra 42 design presentati da 13 designer.
The website is ffLivewire.com
none really
Desired Color Scheme:
see Description
Desired Style:
Something eye catching, some thing that Nike or Reebox would put out.
Accepted File Formats:
Any common file format that a screen printer would use.
The website is ffLivewire.com... We are a Football news site for fantasy football enthusiasts. We would like to sell very good looking t-shirt/sweatshirts that not only capture the eye, it advertises the website as well.
I am open to shirt colors. White is cheaper, but color is better, IMO. I like black or blue, or earth-tone colors.


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Full Demo
February 27, 2013
Full Download:1.85 GB of content • 24 Bit, 44.1 kHz WAV Audio • MIDI Song file • Stems wav files • 136 BPM • Track Key: F
Following the successfully vol.1 pack of Uplifting Track Stems we are proud to present you the vol.2 of this series.
This pack contains a full Uplifting Trance production, broken down into individual tracks of drums, baselines, melodies, pads & Mixed FX plus the MIDI song file of each track allowing you full flexibility to control and recreate the melodies and harmonies your own favorite synth sounds.
This Project has been made by Michael Angelo known for his releases on labels such as Black Hole Recordings,Enhanced Recordings and High Light Records.
Download this pack and recreate the structure of the HighLife Samples demo tune with the added option of adding your own personal style.
If you are a Cubase user we inform you that is pack is also released as a full template Cubase 6 project.You will find it on our label catalogue as a "Cubase Trance Project Vol.1"
1.85 GB of content • 24 Bit, 44.1 kHz WAV Audio • MIDI Song file • Stems wav files • 136 BPM • Track Key: F


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Wizards Game 36 vs. Detroit Pistons Live Twitter Blog
6:57:50 PM: Your inactives: Javaris Crittenton, Mike Miller & Andray Blatche (team suspension). Your 'not-in-the-buildings': Gilbert Arenas
6:59:04 PM: Poor Wiz radio guy Dave Johnson, he has to say things like, "You have every reason to be encouraged … esp. after the last two games."
7:00:41 PM: Meanwhile, U have a player suspended 4 complaining about not getting shots & more players going 2 court everyday 2 speak on their teammates
7:03:20 PM: Washington Wizards: Where "Encouraging" Is A Fairy Tale
7:03:54 PM: Read the Wiz Insider pregame report from @MrMichaelLee http://bit.ly/88xsYE
7:06:11 PM: Guess the good news is that if this were the playoffs, Mike Miller would be playing, at least that's what Flip Saunders said. #silly
7:06:50 PM: It's Military Appreciation Night here @ the Verizon Center … so a HUGE thank you to all the soldiers out there.
7:08:04 PM: Of course, one poor solider was on the jumbotron b/f the game saying that this is his 1st NBA game. These 2 teams R a combined 23-48. Damn.
7:11:04 PM: Ran into Steve Buckhantz in the bathroom b/f game. He said, "At least the water is warm." Guess the arena is cold b/c the few fans here.
7:14:01 PM: My bad, Gene Wang did tonight's post on @wizardsinsider
7:16:40 PM: Flip Saunders calls a timeout at the 9:23 mark, Wizards already down 9-2. This team needs a sponsorship from 5-Hour Energy.
7:22:51 PM: Caron thought he could pull a tough step-back baseline jumper on Jerebko. What he found out is that he could only shoot an airball.
7:23:35 PM: Some fan from all the way across the arena yelled, "DEEE-TROIT BAS-KET-BALL!!" & I could hear him loud & clear. Some Pistons fans cheered.
7:25:52 PM: Not sure if it was his 1st instance, but after Hamilton just scored on Nick Young, I saw the kid's head hang. He may be done for the night.
7:26:47 PM: As Richard Hamilton has been wearing Nick Young's ass out, DeShawn Stevenson checks in.
7:31:16 PM: JaVale McGee is FREE! Fly bird fly ….
7:33:04 PM: BTW, JaVale McGee is on the cover of tonight's GameTime, trying to fly … http://www.flickr.com/photos/truth_about_it/4270443488/
7:36:17 PM: Boykins was lined up on FT line b/t Jerebko & Villanueva so Wiz could press after Jamison FT. Some fan yelled, "Get the rebound Earl!!"
7:37:42 PM: Nope RT @BulletsForever Can't help but wonder if this is fools gold from Foye. Not that he can't play, but longterm, do U want him as ur PG?
7:38:31 PM: Something was wrong with Caron Butler's jersey, he changed into a new one @ end of 1st Q. Wizards up 27-21 on DET going into 2nd.
7:40:01 PM: Uh JaVale? Why are you slow getting back on defense in transition? You're a free man! Run son!
7:40:46 PM: Wizards lineup: Boykins, Foye, McGuire, Jamison & McGee. Antawn did NOT have this in mind at the beginning of the season.
7:42:26 PM: @phoenixstan @Wal33d Blatche got suspended 1 gm b/c he was complaining abt his lack of shots after NOLA game on Sun, among other things.
7:44:04 PM: 9:05 left in 2nd, Pistons on a 10-2 run, lead 31-29. Wizards aren't wanting rebounds enough. DET up 19-13 on glass, 8 offensive to 4.
7:47:01 PM: A coordinated "Free Gilbert" yell just came from the upper deck at a quiet moment.
7:52:26 PM: The Washington Wizards: Where Game Slippage Happens. (Can you tell that I'm one jaded SOB? I'm sorry, I really shouldn't be this way)
7:53:04 PM: I'm only going to Tweet positive things for the rest of the 2nd quarter. DET up 40-36, 5:21 left.
7:54:45 PM: This team looks positively lackluster. No energy during timeouts. No encouragement. They're all like "whatever".
7:55:47 PM: RT @BulletsForever Bury the malcontents! They don't exist! RT @craigstouffer: No pre-Chipotle video (starring Blatche) tonight.
8:07:23 PM: Chris Wilcox was once pulled over by police w a .357 revolver, ammunition and spent shell casings in his car, no permit. He's playing 2nite.
8:07:55 PM: RT @BulletsForever Wizards are shooting 17% in the quarter. In a related story, Earl Boykins has played the entire quarter.
8:09:17 PM: The half is over and Detroit is up 48-38 on Washington. Two teams combined to shoot 32-85.
8:24:14 PM: Bench Points: DET 23 (Villanueva & Chucky Atkins), WAS 5 (McGee & Boykins) — DET up 18-10 in Points in Paint.
8:24:38 PM: RT @rashad20 The Wizards shot 19% in the 2nd quarter…in an unrelated note, it is currently 19 degrees outside the Verizon Center
8:25:22 PM: RT @BulletsForever Put it this way: when U can't score w/o Randy effin Foye, U R terrible. No disrespect 2 Foye, but he shouldn't be vital
8:28:07 PM: Wonder what happened to that ESPN 'Pick A Play For Flip Saunders/The Wizards' thing. Died pretty quick, just like the Wizards … I guess.
8:30:24 PM: New straw time for Caron Butler. I need to score an interview with the supplier. Timeout, 9:09 left in 3rd, Detroit up 50-46 on Wizards.
8:32:05 PM: Loudest cheers of the night in Verizon so far: A Randy Foye 3 in 1st Q, Very old couple giving a long smooch on Kiss Cam.
8:34:24 PM: In other observations: the names on the back of the Pistons' jerseys are too small.
8:36:30 PM: RT @zgordon5 Told @MrMichaelLee to keep his head up as he walked by, he says "I got to, I'm not facin charges!"….that kinda year..lol
8:41:53 PM: Damn. Randy Foye with a nice 2-handed dunk on the break. 61 Tie. The Wiz Zone D has fared okay on the last couple of defensive possessions.
8:49:44 PM: At the end of 3 quarters, Detroit leads 67-64. Wiz out-rebounded Pistons 12-5 in 3rd Q.
8:50:49 PM: Boykins, Foye, Butler, Jamison & McGee start 4th Q for Washington.
8:55:39 PM: Boy, Flip Saunders was REALLY pissed off at that early shot clock pull-up jumper by Foye at the 8:41 mark.
8:58:18 PM: Boykins is -13, Dom McGuire is -10, JaVale McGee is -3. The rest of the Wizards are either positive or even in plus/minus. 78-74 DET.
9:00:43 PM: Butler hit a couple nice rhythm jumpers, Wiz down 79-78 …. hope he drives to the hoop next time.
9:02:02 PM: Nope. Caron answered a Villunueva 3 w/ another pull-up jumper against Jerebko. C'mon Juice! You had the lane! 82-78 DET, 5:55 left in 4th
9:04:29 PM: After brief spell on bench, Foye back 4 Boykins. Can't read lips, esp. from top of sec. 104, but think Flip said, "No more MF stupid shots."
9:06:02 PM: Charlie V just hit his 5th three, he's only missed 1. Pistons go on run & just like that, they're up 87-78. Timeout Wizards.
9:16:17 PM: Detroit's next bucket just might be a dagger folks. Up 93-86, 1:53 left, Haywood at the line for two.
9:17:24 PM: Haywood missed both FTs and it's coat check time … fans begin to exit stage left from this comedy of errors that is the Washington Wizards
9:18:06 PM: Dagger. Rip Hamilton hits a two, Caron Butler misses a three. 95-86, 1:19 left….
9:18:46 PM: No Wizards fans are booing … yet. It's almost like they don't even care enough to boo.
9:20:39 PM: And as Gilbert Arenas would tweet, "Zip It Up & Zip It Out", the Wizards lose another, 99-90 to Detroit.
10:11:36 PM: Nothing much from Wizards' locker room. It's they know they're bad & that anyone could get traded, so proceed w 'go thru motions' b-ball.
10:16:42 PM: In his presser, even Flip Saunders seemed resigned to the "situations", i.e., he wasn't as upset as he's been w previous losses.
10:19:25 PM: IMO, Flip has accepted that he's coach of a losing team & prolly hopes that Grunfeld leaves him w something 2 work with after the blow up.
10:21:25 PM: Maybe they can be the Washington Groundhogs. (But Jamison didn't say "its like Groundhog Day" tonight.)


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In this Level 2 Green Light Reader based on Curious George, the Emmy–Award winning PBS TV show, George wants to help his friend Bill build an igloo. But will George's supersized igloo be too cold to sleep in?
In this snowy adventure based on the Emmy Award–winning PBS TV show, Curious George can't wait to help his friend Bill build an igloo and sleep in it overnight. But George thinks Bill's igloo is too small. He decides to build his own supersized igloo—big enough for a party! Will such a big igloo be too cold for a little monkey? This fun-filled Level 2 Green Light Reader includes an activity that helps kids identify things that melt as well as instructions for making their own mini-igloo out of marshmallows. For more monkey fun, check out www.curiousgeorge.com and discover all the latest books, promotions, games, activities, and more!
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Medical Marijuana: State vs. FederalPosted on: December 8, 2009 at 2:29 a.m.
A new federal policy under the Obama administration has raised a lot of questions and concern among marijuana users throughout the country, particularly in California. The new policy states that the federal government will not seek to arrest medical marijuana users and suppliers as long as they conform to state laws, a departure from tough federal marijuana laws under the Bush administration. The irony of this new policy lies in one of California's largest cities; Los Angeles medical marijuana dispensaries were once plentiful and the city, along with the state of California, was an advocate for legalized marijuana use. Around the time that the federal policy was announce, however, Los Angeles began to tighten its grip on medical marijuana dispensaries, in a puzzling display of role reversal. This polarization of opinion on behalf of Los Angeles has left many users in limbo when it comes to the legality of marijuana. The recent crackdowns on medical marijuana dispensaries seem to back track the cities stand on the issue before the federal policy was put into place, leaving users even more confused than before.
Unfortunately, there is still ambiguity within Los Angeles county laws on marijuana use and that has people scratching their heads on the legality of their activities. In Los Angeles, you are technically allowed to have small amounts of marijuana for personal use, but that all depends on which enforcement agency finds them on you. Medical marijuana use is legal in California, so state and city law enforcement agents might not arrest you for possession in your own home. If, however, you are found to have marijuana outside of your home, you might be arrested and charged with a misdemeanor drug possession offense. The sentencing aspect of a marijuana arrest provides even more leeway and confusion to offenders, if you are a first time offender you can forego tougher sentences by enrolling in a drug treatment program and by completing the program and avoiding being arrested or convicted your record is wiped clean.
This ambiguity in laws and sentencing techniques can leave anyone baffled, but an experienced Los Angeles drug defense attorney can help you navigate through all of the confusion of medical marijuana laws. The experienced defense lawyers at Kestenbaum, Eisner & Gorin, LLP can help you sort through the drug laws in Los Angeles and will work on your behalf to minimize your sentence or have your case dismissed.
Tagged as: los angeles medical marijuana attorney
Medical Marijuana Dispensary BattlesPosted on: November 11, 2009 at 7:12 p.m.
A particularly contentious area of the law for Los Angeles criminal defense attorneys is medical marijuana law. While medical marijuana was legalized in Los Angeles and the rest of the state, law enforcement (both state and federal) continue to raid medical marijuana dispensaries. In fact, this battle is taking place throughout the state of California.
Arguments over medical marijuana use, as well as in other cities, are heating up all over California. By some accounts, there are more medical marijuana dispensaries in Los Angeles than there are Starbucks and 7/11 stores. In Fresno, the fight over medical marijuana has recently been focusing on zoning laws and the overlap of legal jurisdiction between the city, state and national government. Fresno recently adopted zoning laws that effectively prohibit medical marijuana dispensaries from operating in city limits. Federal policy technically makes the use of marijuana illegal, even for medical purposes. The Obama administration, however, has taken a less forceful track than the Bush administration, saying it will not prosecute medical marijuana dispensaries or the patients who use it in states where it is legal by state law.
Fresno's nine recognized marijuana dispensaries have been ordered to close their doors while lawyers hash out their legality in court. In 2006, Fresno very obviously attempted to ban dispensaries within city limits by drafting zoning laws that specified that all marijuana dispensaries must comply with both state and federal laws in order to operate. Since federal law prohibits marijuana dispensaries, no dispensary could fully comply and remain open legally. Opponents of the use of marijuana for medical purposes argue that Fresno's zoning laws banning marijuana dispensaries are supported by federal law, which supersedes state law. Those in favor of medical marijuana argue that states' rights and California state law should prevail, keeping the dispensaries open. Trial in the case has been set for January, 2010. In the meantime, opponents of the dispensaries have asked the presiding judge for a temporary restraining order that would shutter all of the city's dispensaries until after the trial. The order was granted on October 28th. Attorneys for the city's nine dispensaries will appeal the decision in an attempt to keep the dispensaries open until the trial begins.
Medical marijuana policies are likewise subject to the same confusion. While city zoning laws have not gone so far as to ban marijuana dispensaries, possession, sale or the manufacture of marijuana for medical purposes may still get you arrested, depending on the law enforcement agency that arrests you. With such a complicated criminal matter, you need an experienced criminal defense attorney by your side.
Tagged as: los angeles medical marijuana attorney, los angeles medical marijuana dispensary
President Obama's Marijuana Policy ChangesPosted on: March 9, 2009 at 8:02 a.m.
If there is an area of criminal law in Los Angeles that regularly frustrates Los Angeles criminal defense attorneys it is the area of law regarding medical marijuana. Medical marijuana lawyers are constantly battling between state and federal regulations, and during the Bush Administration there were major challenges. Now however, under President Obama, the policy regarding medical marijuana in Los Angeles may have taken a major turn.
With the recent change in presidents comes a very big shift in attitude towards marijuana. In late February of this year, newly-appointed Attorney General Eric Holder stated that President Obama intended to end many of the practices the Bush administration had used in regard to marijuana patients and providers.
Under the Bush administration, federal law enforcement officials can and did frequently arrest marijuana users and providers, as well as raid medical marijuana dispensaries, even in states like California where they were legal under state law. President Obama intends to honor states rights by allowing the 13 states that currently allow marijuana use for medical purposes to continue to do so without fear of federal law enforcement intervention.
While President Obama strictly maintains that he is not in favor of legalizing marijuana, a White House statement issued several weeks ago stated "The President believes that federal resources should not be used to circumvent state laws," and is expected to appoint new members for his drug policy team that are of the same opinion. The new presidents administration is expected to encourage each state to determine their own policies regarding marijuana and its use, which is a clear departure from policies in the Bush administration.
Unlike the previous president, Obama intends to mostly treat the majority of drug use as a health issue instead of a criminal justice issue, a sentiment he often voiced during his campaign for the presidency. The implications of this policy change could reach far and wide in California where it is currently a misdemeanor to be found in possession of marijuana and a felony to be found manufacturing or distributing the substance without a medical exemption.
With the application of federal law somewhat in flux, marijuana-related criminal charges in California require some delicate handling. If you have been charged with a crime relating to marijuana, contact a qualified criminal defense attorney immediately to begin reviewing the facts of your case.
With 50 years criminal defense experience, Kestenbaum, Eisner & Gorin specializes in successfully defending charges related to the Sales and Transportation of Marijuana (Penal Code Section 11360), Possession for Sale (Penal Code Section 11359), and Possession (Penal Code Section 11357). Our Los Angeles medical marijuana law firm has been recognized as a Top 5% U.S. Law Firm based on peer reviews from other attorneys, judges, and prosecutors, in the area of legal ethics, professionalism, and judgment. We have vast experience in defending all criminal matters including drug cases involving very large quantities of marijuana.
Tagged as: los angeles medical marijuana attorney
Eisner Gorin LLP has been recognized as one of the best U.S. law firms, based on the experience, professionalism, and ethics of its criminal defense lawyers and attorneys. We aggressively defend clients in all Southern California courtrooms on state and federal charges, including DUI, DMV, misdemeanor, felony, juvenile cases, in the following communities and courthouses.


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Team Peugeot Hansen brought home a dominating victory in France's stage of the 2015 FIA World Rallycross Championship at Lohéac. Timmy Hansen managed to secure the 208 WRX's fourth victory and eight podium finish of the season.
Before the race Team Principle, Kenneth Hansen stated that a victory at Lohéac was "mandatory" as there was enormous pressure for Peugeot to perform in front of their home crowd. A total of 65,000 people came to spectate at one of the most celebrated venues on the Rallycross calendar. Peugeot certainly made their presence prominent at the venue by showcasing their collection of racing cars on display which included the incredible 208 T16 Pikes Peak.
The two Peugeot 208 WRX Supercars already showed promise racing to victory at previous venues including Norway, Canada and Germany. The cars host 550bhp four-cylinder two-litre turbocharged engines combined with Sadev 6-speed transmission which can achieve 0-100 km/h in approximately 2 seconds!
In the hands of the 23 year old Swedish driver, Timmy Hansen, the 208 WRX's qualifying heats were sensational. In the semi-final Timmy made a perfect run to secure the all-important 1st place on the grid for the final. This allowed for him to pull away in the final while the rest of the field were scrambling for position, putting in six faultless laps ending the tremendous weekend with his second win of the season.
"I can't find words to describe how good it feels to have won in France with Peugeot! The French love French cars and I was thrilled with the support they gave me." Timmy Hansen, #21 208 WRX
The weekend did not go so well for French team-mate, Davy Jeanney, with a variety of setbacks and an unfortunate incident led to the car being forced off-track by a competitor during the semi-finals.
"I hit a guard-rail head-on and there was no way I could have continued after that. The team now faces a big job to get the car ready in time for Barcelona." Davy Jeanney, #17 208 WRX
Timmy's win at the home race has consolidated Team Peugeot Hansen's lead at the top of the Team Standings with 328 points with Ford Olsbergs MSE behind at 275 points. The excitement will carry on to the next race, which will be held at the Circuit de Barcelona-Catalunya for the opening World Rallycross of Spain.
Image Credits: FIA WorldRX


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New Long-Term Data Presented at AASLD Show Reduction in Liver Fibrosis and Cirrhosis in a Cohort of Patients with Lysosomal Acid Lipase Deficiency (LAL-D) Treated with Kanuma® (sebelipase alfa)
--Longer Duration of Kanuma Treatment Associated with Greater Reductions in Fibrosis Stage--
--Additional Long-Term Data Show Rapid and Sustained Reduction in ALT, a Marker of Liver Injury, in 98 Percent of Kanuma-Treated Patients at 76 Weeks--
Friday, November 11, 2016 8:00 am EST
NEW HAVEN, Conn.
Public Company Information:
NEW HAVEN, Conn.--(BUSINESS WIRE)--Alexion Pharmaceuticals, Inc. (Nasdaq: ALXN) announced today that researchers presented new longer-term data from an ongoing, open-label extension of the pivotal Phase 3 ARISE trial of Kanuma ® (sebelipase alfa) in children and adults with lysosomal acid lipase deficiency (LAL-D), a genetic and progressive ultra-rare metabolic disease. Two-thirds of patients (8/12) treated with Kanuma for 52 weeks had a reduction in liver fibrosis stage from baseline, as measured by Ishak score. Moreover, half of patients (6/12) achieved at least a 2-stage reduction, including five patients who had fibrosis at baseline and one who had cirrhosis at baseline. Reduction of liver fibrosis stage was accompanied by sustained improvements in alanine aminotransferase (ALT), LDL cholesterol (LDL-C), and liver fat content through 52 weeks of Kanuma treatment.1 These data were reported in a poster presentation at The Liver Meeting 2016, the annual meeting of the American Association for the Study of Liver Diseases (AASLD), in Boston.
Researchers at AASLD also presented new long-term data from the ARISE study showing rapid and sustained improvements in important markers of liver injury and lipid abnormalities in children and adults with LAL-D treated with Kanuma. With 76 weeks of Kanuma treatment, nearly all patients (98 percent) had a sustained reduction in ALT levels, with a mean reduction from baseline of 56 percent.2
"LAL-D is a devastating and life-threatening disease in which half of children and adults will progress to fibrosis, cirrhosis, or liver transplant within just three years. We are very encouraged that the data presented at AASLD show, for the first time, that Kanuma may have the potential to halt and even reverse the progression of liver damage for patients receiving ongoing treatment," said Martin Mackay, Ph.D., Executive Vice President and Global Head of R&D at Alexion. "Importantly, the greatest impact was observed in those patients who had more significant liver fibrosis at baseline. Findings from this study support the value of early and long-term treatment with Kanuma."
LAL-D is a genetic, chronic and progressive ultra-rare metabolic disease associated with significant morbidity and premature mortality.3 Ultra-rare diseases are defined as diseases that affect fewer than 20 patients per 1 million of the general population.4 Patients with LAL-D can experience a rapid onset of life-threatening disease manifestations, and without treatment, the youngest patients typically face premature death within a matter of months. Unfortunately, children and adults with LAL-D are often undiagnosed or misdiagnosed, despite experiencing progressive organ damage that can lead to severe and life-threatening outcomes. LAL-D is caused by genetic mutations that result in a marked decrease or loss in vital LAL enzyme activity in the lysosomes across multiple body tissues, leading to the chronic build-up of cholesteryl esters and triglycerides in the liver, blood vessel walls, and other organs.3,5
Kanuma is the only approved therapy to address the underlying cause of LAL-D.
Change in Liver Fibrosis in Children and Adults with Lysosomal Acid Lipase Deficiency After 52 Weeks of Sebelipase Alfa (ARISE Trial) 1
Researchers presented data from the ongoing, open-label period of the Phase 3 ARISE (Acid Lipase Replacement Investigating Safety and Efficacy) trial of Kanuma in children and adults with LAL-D that evaluated the effect of long-term Kanuma treatment on liver fibrosis stage. This poster was selected as a Presidential Poster of Distinction at AASLD. Following the 20-week, double-blind, randomized, placebo-controlled period of the study, 65 patients began the open-label phase and were treated with Kanuma for up to 130 weeks, including 35 patients who were treated with Kanuma during the double-blind period and 30 who were treated with placebo during the double-blind period. Paired liver biopsies were taken in 20 patients (ages 5 to 59 years) at baseline and study Week 52, including 12 patients who initially received Kanuma in the double-blind period and 8 patients who initially received placebo in the double-blind period. The 7-point Ishak staging system was used to assess fibrosis and cirrhosis.
Of the 12 patients who were biopsied at baseline and 52 weeks of Kanuma treatment, six achieved a ≥2-stage reduction in liver fibrosis from baseline, and two achieved a 1-stage reduction. Three patients showed no change in fibrosis stage and one patient had an increase. Of the six patients who had a 2-stage reduction from baseline to week 52, one had cirrhosis and five had stage 3 fibrosis at baseline. In addition to achieving a 2-stage reduction in liver fibrosis, this group of patients demonstrated mean reductions of 61 percent in ALT, 40 percent in LDL-C, and 32 percent in liver fat content after 52 weeks of treatment. Among the 8 patients who were biopsied at baseline and at study week 52 (reflecting 30 weeks of Kanuma treatment), four had a 1-stage reduction in fibrosis, three had no change, and one had an increase.
Additionally, among patients with paired biopsy data at baseline and week 20, a significantly higher proportion of patients in the Kanuma arm had improvement or no change from baseline in hepatic steatosis compared with patients in the placebo arm (94 percent vs. 50 percent; p = 0.0184). Among the 12-patient biopsy cohort that received Kanuma for 52 weeks, median percentage of steatosis decreased by 37 percent from baseline.
"This is the first study to provide evidence of change in Ishak fibrosis score in children and adults with LAL-D treated with Kanuma," said clinical trial investigator Zachary Goodman, M.D., Director of Hepatic Pathology Consultation and Research at Inova Fairfax Hospital, Falls Church, Virginia. "In this cohort of patients, study results showed that longer Kanuma treatment led to greater reductions in fibrosis, with the largest decreases seen after 52 weeks of treatment. The results are extremely encouraging and support the clinical benefits of early and long-term Kanuma treatment in patients with LAL-D."
Most adverse events during the open-label extension period were mild to moderate in intensity. The most common treatment-emergent adverse events were nasopharyngitis, headache, pyrexia, and cough. No patient discontinued the open-label study because of adverse events. Thirteen patients (20 percent) experienced an infusion-associated reaction during the open-label period. One patient had a serious reaction that was considered treatment-related; the patient stopped taking Kanuma but later resumed therapy.
Long-Term Benefit of Sebelipase Alfa over 76 Weeks in Children and Adults with Lysosomal Acid Lipase Deficiency (ARISE Trial) 2
Researchers at AASLD also presented new 76-week results from the open-label extension of the ARISE trial in patients with LAL-D. Fifty-two week findings were previously reported at the 5th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition (WCPGHAN) in October 2016, demonstrating that nearly all patients (97 percent) who were treated with Kanuma for 52 weeks had a rapid and sustained reduction in ALT, with 47 percent achieving ALT normalization.
New data presented at AASLD showed that after 76 weeks of Kanuma treatment, 98 percent (60/61) of patients had a sustained reduction in ALT from baseline, 51 percent (31/61) achieved ALT normalization, and 65 percent (37/57) achieved aspartate aminotransferase (AST) normalization. Marked and sustained improvements in ALT and AST occurred when patients who had initially received placebo during the double-blind period switched to Kanuma, mirroring those improvements observed in patients receiving Kanuma from the start of the double-blind period. Patients also had improvements in lipid abnormalities, including decreases in mean LDL-C, non-HDL cholesterol, and triglycerides, and increases in mean HDL cholesterol.
"The 76-week ARISE data presented at AASLD continue to reinforce the rapid and sustained improvements in dyslipidemia and markers of liver injury associated with Kanuma," said study investigator Katryn Furuya, M.D., Associate Professor of Pediatrics, Division of Pediatric Gastroenterology and Solid Organ Transplant, Mayo Clinic, Rochester, Minn. "These findings support the need for ongoing Kanuma treatment in pediatric and adult patients with LAL-D, who historically have faced progressive and life-threatening complications in the absence of an effective therapy."
The safety profile of Kanuma during the extended open-label period, as described above, was consistent with that observed in the double-blind period.
About Lysosomal Acid Lipase Deficiency (LAL-D)
LAL-D is a genetic, chronic, and progressive ultra-rare metabolic disease associated with significant morbidity and premature mortality.3 In patients with LAL-D, genetic mutations result in a marked decrease or loss in activity of the vital LAL enzyme. This leads to marked accumulation of cholesteryl esters and triglycerides in vital organs, blood vessels, and other tissues, resulting in progressive and multi-organ damage including fibrosis, cirrhosis, liver failure, accelerated atherosclerosis, cardiovascular disease, and other devastating consequences.3,5
LAL-D affects patients of all ages with clinical manifestations from infancy through adulthood and may have sudden and unpredictable clinical complications. Infants experience profound growth failure, liver fibrosis, and cirrhosis, with a median age of death at 3.7 months.6 In an observational study, approximately 50 percent of children and adults with LAL-D progressed to fibrosis, cirrhosis, or liver transplant in 3 years.7 The median age of onset of LAL-D is 5.8 years, and the disease can be diagnosed with a simple blood test.8,9
About Kanuma ® (sebelipase alfa)
Kanuma® (sebelipase alfa) is an innovative enzyme replacement therapy that addresses the underlying cause of lysosomal acid lipase deficiency (LAL-D) by replacing the missing vital enzyme and reducing substrate accumulation in the lysosomes of cells throughout the body. In clinical studies, treatment with Kanuma improved survival in infants with LAL-D and led to normal development. Kanuma treatment in children and adults led to rapid and significant reductions in ALT and liver fat content, as well as significant improvements in lipid parameters, which were sustained with long-term treatment.
Kanuma is approved in the United States, European Union, and Japan. For its innovation in treating patients with LAL-D, Kanuma received the prestigious 2016 German Prix Galien Award in the Orphan Product category.
Hypersensitivity reactions, including anaphylaxis, have been reported in KANUMA-treated patients. In clinical trials, 3 of 106 (3 percent) patients treated with KANUMA experienced signs and symptoms consistent with anaphylaxis. These patients experienced reactions during infusion with signs and symptoms including chest discomfort, conjunctival injection, dyspnea, generalized and itchy rash, hyperemia, swelling of eyelids, rhinorrhea, severe respiratory distress, tachycardia, tachypnea, and urticaria. Anaphylaxis has occurred as early as the sixth infusion and as late as 1 year after treatment initiation.
In clinical trials, 21 of 106 (20 percent) KANUMA-treated patients, including 9 of 14 (64 percent) infants and 12 of 92 (13 percent) pediatric patients, 4 years and older, and adults experienced signs and symptoms either consistent with or that may be related to a hypersensitivity reaction. Signs and symptoms of hypersensitivity reactions, occurring in two or more patients, included abdominal pain, agitation, fever, chills, diarrhea, eczema, edema, hypertension, irritability, laryngeal edema, nausea, pallor, pruritus, rash, and vomiting. The majority of reactions occurred during or within 4 hours of the completion of the infusion. Patients were not routinely pre-medicated prior to infusion of KANUMA in these clinical trials.
Due to the potential for anaphylaxis, appropriate medical support should be readily available when KANUMA is administered.
Hypersensitivity to Eggs or Egg Products: Consider the risks and benefits of treatment in patients with known systemic hypersensitivity reactions to eggs or egg products.
The most common adverse reactions are: In Patients with Rapidly Progressive Disease Presenting within the First 6 Months of Life (≥30 percent): diarrhea, vomiting, fever, rhinitis, anemia, cough, nasopharyngitis, and urticaria. In Pediatric and Adult Patients (≥8 percent): headache, fever, oropharyngeal pain, nasopharyngitis, asthenia, constipation, and nausea.
Please click here for the full Prescribing Information.
About Alexion
Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion is the global leader in complement inhibition and has developed and commercializes the first and only approved complement inhibitor to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), two life-threatening ultra-rare disorders. In addition, Alexion's metabolic franchise includes two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D). Alexion is advancing the most robust rare disease pipeline in the biotech industry with highly innovative product candidates in multiple therapeutic areas. This press release and further information about Alexion can be found at: www.alexion.com.
Forward-Looking Statements
This news release contains forward-looking statements, including statements related to potential medical benefits of Kanuma ® (sebelipase alfa) for lysosomal acid lipase deficiency (LAL-D). Forward-looking statements are subject to factors that may cause Alexion's results and plans to differ from those expected, including, for example, decisions of regulatory authorities regarding marketing approval or material limitations on the marketing of Kanuma for LAL-D, delays in arranging satisfactory manufacturing capabilities and establishing commercial infrastructure for Kanuma for LAL-D, the possibility that results of clinical trials are not predictive of safety and efficacy results of Kanuma in broader or different patient populations, the risk that third party payors (including governmental agencies) will not reimburse for the use of Kanuma at acceptable rates or at all, the risk that estimates regarding the number of patients with Kanuma and observations regarding the natural history of patients with Kanuma are inaccurate, and a variety of other risks set forth from time to time in Alexion's filings with the Securities and Exchange Commission, including but not limited to the risks discussed in Alexion's Quarterly Report on Form 10-Q for the period ended June 30, 2016 and in Alexion's other filings with the SEC. Alexion does not intend to update any of these forward-looking statements to reflect events or circumstances after the date hereof, except when a duty arises under law.
|Goodman Z, Burton B, Alaparthi L, et al. Change in Liver Fibrosis in Children and Adults with Lysosomal Acid Lipase Deficiency After 52 Weeks of Sebelipase alfa (ARISE Trial). Poster presented at the American Association for the Study of Liver Diseases (AASLD) Annual Meeting, Boston, November 11. Abstract 561.
|Furuya KN, Marulkar S, Friedman M, et al. Long-Term Benefit of Sebelipase Alfa over 76 Weeks in Children and Adults with Lysosomal Acid Lipase Deficiency (ARISE Trial). Poster presented at the American Association for the Study of Liver Diseases (AASLD) Annual Meeting, Boston, November 11. Abstract 564.
|Bernstein DL, et al. Chloesteryl ester storage disease: review of the findings in 135 reported patients with an underdiagnosed disease. J Hepatol. 2013;58:1230-43. doi:10.1016/j.jhep.2013.02.014.
REGULATION (EU) No 536/2014 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 16 April 2014 on clinical trials on medicinal products for human use, and repealing Directive 2001/20/EC. http://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32014R0536&qid=1421232837997&from=EN.
|Reiner Z, et al. Lysosomal acid lipase deficiency – an under-recognized cause of dyslipidemia and liver dysfunction. Atherosclerosis. 2014;235:21-30. doi:10.1016/j.atherosclerosis.2014.04.003.
|Jones SA, et al. Rapid progression and mortality of lysosomal acid lipase deficiency presenting in infants. Genet Med. 27 August 2015. doi:10.1038/gim.2015.108.
|Data on file, Alexion.
|Burton BK, Deegan PB, Enns GM, et al. Clinical Features of Lysosomal Acid Lipase Deficiency. J Pediatr Gastroenterol Nutr. 2015;619-25. doi: 10.1097/MPG.0000000000000935.
|Hamilton J, et al. A new method for the measurement of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2. Clin Chim Acta. 2012;413:1207-10. doi:10.1016/j.cca.2012.03.019.


text:
Saturday, May 06, 2006
Bruce Boxleitner
The only things Bruce will be remembered for -- Tron and his ability to unleash hell on a caesar salad.
Posted by Alex at 11:29 AM
Labels: bruce boxleitner
1 comment:
That is some buldge in his pants. YUM!!
- August 5, 2006 at 9:53 PM
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Help for library patrons
What is QuestionPoint?
QuestionPoint is a service that many libraries use to help them answer questions for their patrons.
QuestionPoint automatically creates an account for you the first time that you ask a librarian a question. Your account is based on the e-mail address that you provided when you asked your question. The initial password for your account is sent to that e-mail address.
Your account contains your questions and the librarian's answers.
Why did the QuestionPoint Patron Logon page appear in my chat session with a librarian?
It appeared because your chat session ended unexpectedly when your communication connection with the librarian stopped working. When this happens, the QuestionPoint service displays the logon page for your patron account.
If the logon page appears, try one of the following suggestions if you provided your e-mail address at the beginning of the session:
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Click the Password link at the top of any page in the account if you want to change your password.
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If you chatted online with a librarian, you should receive the chat transcript soon after the chat session ends. The transcript is sent in an e-mail message and is also included on the My Response page in your account.
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Go to your library's web site and follow the instructions there to ask a new question or to request assistance for a previous question.
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text:
Every Koken Socket goes through a strict manufacturing processes to ensure the highest quality standards are met. With over 60 years of design and research, you can always be assured your Koken sockets are amongst the best in the world.
Step 1: Forging of the SocketUpper and lower punches of the press machine apply several hundred tons pressure on each cut section of steel rod. The forged steel immediately heats up to 300′ G due to the faction of the steel molecules caused by the extreme force of the press machine.
Step 2:Turning the socket
The turning process machines the forged steel sections into required shapes and dimensions. The MG ( Machining Center ) operates with extraordinary speed and precision.
Step 3: Marking the SocketThe article number, size, logo, production number, and MADE IN JAPAN are marked on the products after the turning process.
Step 4:Heat TreatmentTo make the tools stronger and more durable, proper heat treatment is critically important The temperature and the time of the heat treatment are strictly regulated by a eery accurate control device.
Step 5: PolishingTo make the product's surface smooth and beautiful, polishing by machine and hand buff.
Step 6: Surface Treatment
After heat treatment, the hand sockets and accessodes are chrome plated. The impact sockets are phosphate plated giving them a black colored finish. Compared with chrome plating, phosphate plated tools will not peel during heavy-duly use. Plating is the final production process.


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You are hereHome ›
It's 'Act 2' for Hill-Murray alums
Former classmates reunite to stage play on the East Side
Years after parting ways to go off to college, a group of former Hill-Murray theater buffs are getting the gang back together to put on a production.
The play, "Don't Shoot the Masseuse," is an original comedic farce set in the 1950s. It was written by Hill-Murray High School alums Marino Eccher and Elizabeth Eccher, who are also co-directing the play. It's slotted to be performed at the Historic Mounds Theatre on the
East Side of St. Paul the third weekend in June.
Getting everyone together was kind of like in the movie "The Blues Brothers," cast member John Komarek says.
"Marino was like, 'Well, we're trying to get the band back together, you in?'" recalls Komarek, who plays Rex, one of the leading roles. Komarek was indeed in. So was nearly everyone who was asked.
The play is "very much in the style of a traditional farce," Marino says.
The production's fundraising website describes it as follows: "Rex, a baseball player moping his way through a charity ball after a break-up with his glamorous girlfriend, could use a friend.
"He finds one - and maybe more - in Lucy, a sweet, sensible masseuse with a penchant for solving problems."
Add into the equation the fact that Rex's ex, Vicki, is present at the charity ball along with her new man, a clueless hunk of a tennis star named Fernando. Not only that, but Rex and Vicki are placed in adjoining rooms at the hotel where the ball is taking place. Throw in some paranoid FBI agents who find communism where there is none, heightened emotional tension, whimsy, and a healthy dose of slapstick, and you will get an idea of how the cast and crew have been describing the play.
"It has a little bit of everything," says Elizabeth Eccher, a 2007 Hill-Murray graduate.
The play has largely been funded by a campaign on the crowdsourcing website Kickstarter. The group put together a call for funding through the site, launching the initiative on March 4.
Within a week, they had succeeded in raising their goal amount.
"We thought it would take at least a month to raise $3,300," co-director Marino Eccher, a 2004 Hill-Murray graduate, stated in a press release. "We were off by 24 days. It's times like this that I like being wrong."
Marino says the list of contributors included some people he knew would help out, but also some that he never imagined would contribute.
"It was just tremendous," he says. "People were incredibly generous."
Over $2,500 of that money came from Hill-Murray grads.
The group will continue to accept contributions through the website through April 3 to make up for additional expenses, including props and costumes. As of March 27, $3,960 has been raised through the site.
Elizabeth says the response showed that the Hill-Murray theater community "never really went away, even though it wasn't tangible for a while."
"It was very touching," she adds.
Inspiration found in Fargo
Marino wrote the original script for the play in the spring of 2011 while working as a journalist in Fargo, N.D.
Fargo was perhaps "a little slower" than he was used to, he says laughing. Not having a lot to do there for fun, he decided to reinvigorate his love of theater, which had more or less gone dormant since he graduated from high school. So he tried out for a play at the Fargo-Moorhead Community Theater.
He got a role in the play, a musical called "The Drowsy Chaperone." Soon after he was in the comedic farce "Lend Me A Tenor" at the same theater. Inspired by the farce, he decided to write one himself.
"I wanted to see if I could take (the structure of a comedic farce) apart and put it back together myself," he explains.
He banged out the script in a couple of months, and then began a slow process of editing and refining it, with the help of his sister Elizabeth, who contributed additional lines including what are some of the best jokes in the script, she says with whimsical pride.
The two have since done a final edit, tightening up the script.
Though delving into artistic ventures with a sibling can sometimes lead to butting heads, the Ecchers say their brother/sister dynamic works to their advantage.
"We have a high comfort level with criticism," Marino says, attributing this to the fact that they are still very close. It helps, he says, that they have similar tastes in movies and plays, and both have writing backgrounds. Elizabeth graduated from Macalester College with a creative writing degree, and Marino graduated from Marquette University with a degree in journalism.
In addition to writing well together, their comfort level makes it easier to co-direct the play, Elizabeth says.
She highlighted the advantages of having two directors -- at times they are able to work on two different scenes at once. This works because they have the same vision about the production, she says.
When "Don't Shoot the Masseuse" was written in the summer of 2011, the two talked about putting the play on in Fargo, but that didn't pan out.
Then, in November 2012, Marino found himself back in the Twin Cities, and was keen on turning his script into a full theatrical production.
He and Elizabeth thought of all their former Hill-Murray theater cohorts who still lived in the area, and they figured they could cobble together a crew.
So they posted a call for actors on Facebook and contacted old theater friends. They had a speedy and overwhelmingly positive response.
"It meant a lot to us for them to show so much enthusiasm," Marino says. It showed "it wasn't just me and Elizabeth blowing smoke."
Shades of "Seinfeld"
They quickly gathered a group of 10 Hill-Murray graduates, who were mostly former theater aficionados from high school, plus one childhood friend of the groups' and one college friend of Marino's. After reading through scripts, they began assigning roles.
Nearly everyone they asked to play a part said yes, Marino recalls.
Komarek, for instance, was onboard as soon as got his hands on the script. After a few script readings and a casting process, the Ecchers asked Komarek to play Rex, the male lead in the play. The 2003 Hill-Murray grad says he agreed without hesitation, adding he "knew it would be loads of fun for everyone involved."
Komarek describes Rex as very "Seinfeld-esque." Everyone around Rex is fairly kooky, he adds, but Rex is "kind of a foundation." He only really loses his cool when he is confronted with anything related to his ex-girlfriend, Vicki. In contrast to Rex is the character of Fernando, the clueless new boyfriend of Vicki's. Komarek describes Fernando as "Kramer-esque" with a lot of physical acting, referring to another character from the TV sitcom "Seinfeld."
Marino explained that the group has "a bit of an age gap."
The most recent Hill-Murray graduate is from 2008, while the oldest graduated in 2001.
Marino explained that this is due to the fact that some are roughly his sister's age, some are from his graduating class, and some are "cream of the crop" people who came before them. He considers the 30-year-olds to be mentors. "It's cool to work with them all these years down the road," he says.
One such mentor is Eric Johnson, who graduated three years before Marino. Johnson "was the funny guy," Marino says, but also someone that he really looked up to - Johnson showed him the importance of "being serious about your craft."
Like other members of the cast, theater was the main extracurricular activity for Johnson at Hill-Murray.
"It was my whole life pretty much in high school," Johnson says. He describes the school as "a big theater school," where many from the cast of "Don't Shoot the Masseuse" were able to participate in three to five plays a year, sometimes more.
"I was really excited and proud for Marino when I saw he wrote this and put it together," Johnson says.
Another cast member Marino cites as a mentor is Heather Fisher, who plays Lucy the Masseuse, Rex's new romantic interest. Fisher was "the prototypical do-everything leading lady in high school," Marino remembers. Fisher graduated from Hill-Murray in 2001.
Scouring for props
The actors are giving themselves a long time to rehearse and hone the play before they take the stage. Though opening night isn't until the second half of June, they began rehearsing the last week of February.
"Given the enthusiasm that people showed, we really feel even more compelled to put out a quality product," Marino says. "We want to hold up our end of the bargain."
The cast is "scouring basements and thrift stores as we speak," Marino adds, trying to find 1950s furniture for the set, which will consist of two rooms in a hotel.
In terms of future productions, the Ecchers have a few things on the backburner. But for now, they just want to focus on putting on "Don't Shoot the Masseuse."
Patrick Larkin can be reached at firstname.lastname@example.com or at 651-748-7816.
Thespian Hill-Murray alums reunite
If you go ...
The new play "Don't Shoot the Masseuse" will begin its run with a free senior citizens preview on Thursday, June 13, at 7:30 p.m. and then continue through the weekend, with Friday, June 14, and Saturday June 15, shows at 8 p.m. and Sunday, June 16, at 2 p.m.
The following weekend's performances will be at 8 p.m. on Friday, June 21, and Saturday, June 22.
Admission will be a suggested $10 donation at the door.
The Historic Mounds Theatre is located at 1209 Hudson Road, just east of Earl Street and north of Interstate 94.


text:
Tell me about Tata Manza interiors?
Tata Manza is the car with spacious impression inside. Simplicity with beauty can be experienced by the dual tone colour theme which includes black-beige and black-plum combination. Center of attraction of the car is its touchscreen multimedia navigation system along with power outlet at front. The interiors of the car are made out of italian leather upholstery. It has enough space for leg and headroom. The driver's seat is adjustable and is equipped with adjustable power steering, so that the people of all heights can drive the car comfortably. It has added digital clock, one-touch-down power windows, air conditioner with heater, automatic climate control and storage tray under co-driver's seat.


text: Office Depot and OfficeMax provide consumers and companies with office supplies, furniture, computers, and electronics. If you're looking for a laptop, desktop, printer, tablet, computer desk, office chair, or some other office essential, this retail should be one of your first stops. During the holiday shopping season, Office Depot and OfficeMax offer more than one opportunity to save. With pre-Black Friday, Black Friday, and Cyber Week sales, the month of November is jammed-packed with multiple chances to pick up office must-haves and holiday gifts – for less.


text:
Gregory Hines plays the ex-convict son of a famed tap-dancer. Taking over his late father's Harlem dance studio, Hines can't shake memories of his childhood, when he was being touted as a dancing prodigy. Challenged to fulfill his destiny by his dad's old cronies--among them such terpsichorean giants as Sammy Davis...more
All Tap cast + crew photos
Movies.com, the ultimate source for everything movies, is your destination for new movie trailers, reviews, photos, times, tickets + more! Stay in the know with the latest movie news and cast interviews at Movies.com.
Copyright © 2020 FANDANGO MOVIES.


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While shopping for holiday cheer can come at a steep price, that's not the case when it comes to wrapping it all up.
That is, if you visit the First Baptist Church storefront in Wylie.
Church employee Jorean Burks says guests are shocked to find out that volunteers will wrap your gifts – free of charge.
The latest news from around North Texas.
"There's no strings attached? Are you sure, are you sure?"
Since Thanksgiving, volunteers have been running the show 12 hours per day.
Their efforts add up to 15,000 wrapped presents. However, 1,500 of those gifts were wrapped just on the Wednesday before Christmas.
The volunteers say they want to take the stress out of the holidays for busy people – to let them focus on having a merry Christmas, instead of getting bogged down by material things.
"Just the fact that you know you helped someone out feels good," said Plano East student and volunteer Victoria Salinas.
While people try to make donations, the church isn't accepting money. Instead, they take prayer cards.
For people like Estella Martinez, getting the hard work of wrapping out of the way lets her focus on the reason for the season.
"This is really, really a blessing," she said.
The volunteers will work until Christmas Eve.
More: First Baptist Wylie