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SA Orthopaedic Journal
versión On-line ISSN 2309-8309
versión impresa ISSN 1681-150X
SA orthop. j. vol.10 no.4 Centurion ene. 2011
Role of ultrasound as a non-invasive method of diagnosis of chronic exertional compartment syndrome
D WassermannI; Z OschmanII
IMBChB, MSc Student, Section Sports Medicine, University of Pretoria
IIMBChB DCH MSc Sports Section Sports Medicine, University of Pretoria
Chronic exertional compartment syndrome (CECS) is a well-recognised condition, which can result in significant morbidity and limitation of activity in athletes and non-athletes alike. At present invasive intramuscular pressure (IMP) measurements are still considered the gold standard for diagnosing CECS. The non-invasive nature of ultrasound makes it an attractive alternative to direct IMP measurement.
This retrospective study is a literature and case review of 34 subjects with exerciseinduced leg pain who underwent ultrasound compartment measurement for CECS. Eighteen (group P) of 34 were found to be positive. Fifteen of group P demonstrated calf increases of >15 mm and an additional three with increases of <15 mm failed to return to the resting state at 10 mins after exercise. Sixteen subjects demonstrated a normal ultrasound after exercise.
At follow-up (1-2 years) a telephonic interview of 25 participants showed that 15 of the 18 with a positive confirmation of CECS had responded well to surgical decompression and 10 of the 16 negative cases had responded well to conservative treatment.
This study suggests that ultrasound may be a useful tool for the assessment of CECS.
Keywords: ultrasound, exertional, chronic compartment syndrome, non-invasive, intramuscular pressure
Chronic exertional compartment syndrome (CECS) is a well-recognised condition which can result in significant morbidity and limitation of activity in athletes and nonathletes alike. It is defined as an activity-related, reversible, myofascial intramuscular pressure increase, resulting in decreased tissue perfusion and abnormalities in neuromuscular function.1
It typically affects young people who are engaged in sports and usually results from overuse, poor technique or rapidly increased muscle mass following rigorous athletic training. Muscle mass is increased significantly in a short period of time, resulting in a pathological increase in the intramuscular pressure, as the compartment cannot accommodate the transient increase in volume required secondary to increased blood flow.
The pain is intermittent and might be sharp, cramp-like or burning, occurring predominantly during exercise. The level of exercise that precipitates the symptoms may vary considerably, from running a 'four minute mile' to walking around the block. The patients can often continue with the exercise but at a reduced level. At the end of the exercise the pain usually resolves quickly but could persist for hours or even days. CECS symptoms are bilateral in 70% of patients. Pain is most commonly associated with plantar flexion and dorsiflexion of the foot, as the anterior and posterior compartments of the lower leg are most often involved. Sensation in the distal portion of the extremity may be altered, but this is not a consistent finding. Distal arterial pulses are always normal.24
Although most patients presented with activity-related pain, some complained mainly of ankle weakness at fatigue. The effort needed to produce pain may be quite consistent for one patient, and yet differ greatly for another. Swelling during exercise of a runner's already hypertrophied muscles may produce prolonged muscle ischaemia in the affected compartment. It is also conceivable that the muscular swelling could stretch the compartment fascia and stimulate its contained sensory receptors to provoke pain. Displacement or mild pressure on inflamed compartment structures, e.g. tendons, muscle origins or periosteum, could also produce pain following exercise-induced muscle swelling. Hence, leg pain caused by these other conditions could present with similar symptoms and signs found in compartment syndrome, with the exception of the presence of elevated compartment pressure. Muscle hernias were noted in 30% of patients.5,6
Direct intramuscular pressure measurement
The current gold standard for diagnosing compartment syndrome is direct measurement of invasive intramuscular pressure (IMP) and is the primary investigation used to decide on whether to proceed with surgical intervention.1 IMP is measured by insertion of a slit catheter or a similar pressuretransducing device directly into the muscle compartment at risk. This technique is usually accurate and reproducible but is invasive, painful and has an infection risk particularly when measurements at multiple locations are required. Both non-invasive ultrasound (NIUS) and IMP measurement are userdependent investigations, where the method in which the test is performed affects the result.1,7
The classic reference for exertional compartment testing can be credited to Pedowitz and colleagues. The normal resting compartment pressure is between 0 and 8 mmHg. Exercise results in an increase in muscle volume of 8-20%, which results in increased pressure. Following exercise, volume and pressure will return to preexercise levels usually within 5 minutes in a normal compartment. The persistence of increased pressure post exercise is felt to be suggestive of CECS and these pressures may remain abnormal for 20 minutes or longer after exercise.1 Pedowitz et al. also provided the definitions of a positive test for exertional compartment syndromes, which have been the reference for over two decades: resting pressures of >15 mmHg, post exertion pressures of >30 mmHg and delayed pressure measurements of >20 mmHg. Most clinicians also base their diagnoses on an increase of >10 mmHg compared to the resting pressure.8
Despite the fact that IMP measurement is the gold standard for diagnosing CECS, a standard reproducible protocol for IMP testing has not been described. This results in confusion regarding interpretation of results and reduces the tests' reliability.1,8 Key questions remain: Should both legs be tested? Should all compartments be routinely tested or only symptomatic compartment? Are resting, immediate post exertion and delayed post exertion tests required? What resting pressure defines true rest; how long does the patient need to abstain from exercise before the test; and could even walking before the examination affect the pressure results?9
Non-invasive estimations of IMP
The use of peripheral pulse oximetry failed to show reliable decreases in haemoglobin oxygen saturation in the onset of increased IMP and inadequate tissue perfusion.10 The use of near infrared spectroscopy (NIRS) to measure tissue ischaemia shows some promise in the diagnosis of CECS. These studies demonstrated a significant inverse correlation between IMP and oxyhaemoglobin level, and a correlation between oxyhaemoglobin level and perfusion pressure. However, NIRS has trouble measuring oxygen saturation in deep muscle compartments, as the infrared signal can only penetrate tissue approximately 2-3 cm deep, and the instrumentation for NIRS is relatively expensive.10,11
In studies of CECS, magnetic resonance imaging (MRI) has shown increased T2 signal intensity with elevated anterior compartment pressures, but inconsistent T1 abnormalities in the setting of increased IMP. However, due to its large size and cost MRI is infrequently used and limited to radiology departments.10,11
Lynch et al used a non-invasive ultrasonic pulsed phase locked loop (PPLL) device to measure sub-micrometer displacements of the fascia wall. The PPLL device is a low power ultrasound instrument designed to detect and continuously monitor very small displacements between the ultrasound transducer on the skin surface and any subdermal tissue that is capable of reflecting the ultrasound pulse. These displacements occur as a result of volume expansion of the muscle compartment and are related to changes in intramuscular pressure (IMP). The initial experiments were conducted on human cadaver legs, with promising results as a low-cost non-invasive, alternative diagnostic modality but transition from laboratory studies to clinical use will require further development.12
Wieman e$ a# used the PPLL in a human subject experiment. When a thigh tourniquet was inflated in a stepwise fashion to increase the IMP pressure the PPLL was able to detect fascial displacement waveforms corresponding to arterial pulsation and furthermore could distinguish between normal and elevated IMP. There was a linear correlation between PPLL measurements and invasive IMP. In this study the PPLL also showed potential as a non-invasive device for the measurement of IMP.10
Garabekyan et al 7 used a next generation digital non-invasive ultrasound device (NIUD), in comparison to the analogue model used by Wieman et al .10 The analogue model provided indirect estimates of fascial displacement through post acquisition correlation analysis. In contrast, the digital model calculates displacement directly, thereby providing an instantaneous assessment of the output of the position of the muscle fascia. They hypothesised that fascial displacement in experimental compartments with impaired perfusion pressure (PP) would be significantly greater than fascial displacements in control compartments with a normal baseline PP. Acute compartment syndrome (ACS) was generated in the anterior compartments of anaesthetised pigs; the contralateral leg was used as control. IMP was monitored in all compartments with slit catheters; the IMP in experimental compartments was elevated by 10 mmHg increments by infusing 0.045% albumin in saline. Their results proved that fascial displacement in experimental compartments with impaired PP was significantly greater than fascial displacement in control compartments with a normal baseline. One limitation of their study was the use of an animal model. They felt that the most important point to be addressed in future studies was whether the relationship between PP and amplitude of fascial displacement is consistent among different limbs, different compartments, different injuries, and in different animal models including humans.7
Non-invasive ultrasound
Ultrasound, a non-invasive instrument, has had wide application in medicine. It also has the ability to exclude other entities that have to be considered in the differential diagnosis of CECS: shin splints, stress fractures, periostitis, popliteal entrapment and claudication. It also excludes haematomas, abscesses, deep venous thromboses, ruptured Baker's cysts and other masses. Other advantages include safety with no radiation, portability, accessibility, high resolution and a relatively lower cost. More importantly it allows dynamic imaging. Additionally, direct imaging correlation with patient symptoms provides important information to the referring clinicians.4,5,11
Gershuni et al 5 and Brahim and Zaccardelli11 were the first to evaluate the anterior muscle compartment with ultrasound following exercise. They measured the depth (anteroposterior dimension) of the anterior compartment of the lower leg of healthy joggers and nonjoggers before and after exercise. The anterior compartment was exercised on an isokinetic exerciser until the subject complained of pain. The average increase in depth was 8.6%, the increase in joggers 10.1% and in nonjoggers 7.4%. They suggested that measuring the depth increase with ultrasound might complement IMP measurements. Gershuni et al stated that a definite relationship exists between pressure and volume within the leg compartments. Hence, changes in initial volume of the muscle compartment relative to the capacity of the osseofascial compartment boundaries will be reflected in IMP changes. In addition fascial compliance and permeability are involved in the pressurevolume relationship. However studies have already proved that little if any, fluid permeates through the osseofascial boundaries, and unless anatomic or adventitious defects in the boundaries are present, an increase of IMP would be expected for each unit of volume increase. The anterior compartment allows for changes in only one direction depth, which is an indicator of volume changes.5,11
Van Holsbeeck et al 2 examined the lower leg compartments of a group of normal young people, normal athletes and athletes with the clinical diagnoses of CECS with ultrasound. The ultrasound probe position was marked on the skin, depending on the compartment that was evaluated; this was done so that all the repeat measurements were taken at the same level. The depth or anteroposterior dimension of the compartment was measured from the outer border of the superficial fascia of the compartment perpendicular to the outer border of the interosseous membrane or bone surface in millimetres. The measurements of the compartment were obtained at rest, immediately following exercise, and after a 10minute rest period. The exercise consisted of plantar and dorsiflexion of the foot with a 4 kg load at a rate of 60 cycles/min; this was performed for 15 minutes or until symptoms forced the patient to stop. IMP measurements were obtained at the same time that the ultrasound measurements were taken; however, the method used was not described. In their study the normal group demonstrated normal IMP measurements and an increase of dimension ranging between 10% and 15%. After the 10minute recovery period the dimensions returned to that of preexercise. The patients with the clinical diagnoses of CECS all showed abnormal IMP measurements. Onethird of these patients did not show any increase in compartment dimension after exercise, but thickening and rigidity of the interosseous membrane were evident. The other twothirds showed a normal increase in dimension of 10%-15%, which was unexpected with the clearly abnormal compartment pressures. However the return to preexercise dimension was delayed up to six times the upper limit of normal.2
The aim of this review was to determine the role of NIUS in the diagnoses of CECS.
Materials and methods
The ultrasound records of 34 patients (23 males) between the ages of 14 and 65 years conducted between 2006 and 2008 with the clinical diagnosis of CECS were studied. These patients were referred to our unit for an ultrasound examination of the symptomatic muscle compartment to exclude other pathology. All the examinations were conducted by the same operator (>10 years musculoskeletal ultrasound experience) on a Toshiba ultrasound machine equipped with a 5-7.5 MHz lineararray transducer using the technique described by Van Holsbeeck et al .2
At the time of examination the patient had to be free of residual pain. After the first measurement (rest/pre-exercise), the patient was instructed to repeat the activity which precipitated the symptoms. Once the pain/symptoms were present, the activity was discontinued and a second measurement (post-exercise) was taken. If the increase in depth dimension was <15%, a third measurement was taken after a 10minute rest period. We accepted the values used by Van Holsbeeck et al ; a postexercise depth dimension increase of <15% was interpreted as normal and the postexercise depth dimension should return to the preexercise dimension after resting for 10 minutes.
During the examination the patient was instructed to sit relaxed on the bed with legs stretched out, and placed in the same position after exercising (Figure 1). For the measurements the position of the probe was marked on the skin (Figure 2): the probe was placed lightly on the skin without any pressure; each measurement was repeated three times. The depth or anteroposterior dimension of the compartment was measured from the outer border of the superficial fascia of the compartment perpendicular to the outer border of the interosseous membrane or bone surface in millimetres. Only the symptomatic compartment was measured. The examinations were interpreted as positive for CECS if the postexercise depth dimension of the symptomatic compartment increased more than 15% calculated as follows:
post exercise depth (mm) - pre exercise depth (mm)
÷ exerciseivide; pre depth (mm) × 100 =% increase,
or if the compartment increase post exercise was normal (<15%), and the depth (mm) of the compartment did not return to the pre-exercising measurement after the 10-minute rest period (Figures 3 and 4).
In 2009 all subjects were contacted by telephone with the following questions:
1. What treatment did you receive?
2. Was it successful?
Of the 34 patients assessed, the results of 18 patients (group P) were interpreted as positive for CECS. Thirteen of group P had a postexercise depth dimension increase of >15% (group P1). Four of group P had a postexercise depth dimensions increase of <15% (normal) but the depth dimension of the compartment did not return to the preexercising measurement after the 10minute rest period (group P2). One of group P had a postexercise depth dimension increase of <15% (normal) but several hernias became visible (group P3). Sixteen of the patients' (group N) results were interpreted as negative; the depth dimensions increase post exercise was normal or less than <10% and the depth dimension of the compartment returned to the preexercising measurement after a 10-minute rest period. Thickening or rigidity of the interosseous membrane or fascia was not seen as reported by Van Holsbeeck et al in their study (results given in Table I).
Of the 34 subjects, 25 were contactable for a telephonic interview. Fifteen of the group P patients had surgical release of the symptomatic compartment with success. Three of the group P patients could not be contacted. Ten of the group N patients received conservative treatment with success. Six of the group N patients could not be contacted.
A Fisher's Exact Chisquare test was conducted to examine whether there was a relationship between the 'reality' and the observation by NIUS. It is important to note that three of group P and six of group N could not be contacted. The results revealed that there was a significant relationship between the two variables (pvalue smaller than 0.05, p<0.000) at a 95% level of confidence.
Unfortunately the zeros violated the assumptions of the Chisquare test and the results can only be used as a trend. Group P: 15/18=83.33% had operations with success (correctly classified) three not accounted for. Group N: 10/16 = 62.50% had conservative treatment with success (correctly classified) six not accounted for (Figura 5).
Due to an increase in the quest for non-invasive methods to diagnose CECS, we decided to review the ultrasound examinations of cases referred to our practice with a clinical diagnosis of CECS. At present invasive IMP measurement is still considered the gold standard for diagnosing CECS despite the fact that a standard reproducible protocol for IMP measurement has not been described. The non-invasive nature of ultrasound makes it an attractive alternative to direct IMP measurement. It also has the ability to exclude other entities that have to be considered in the differential diagnosis. Other advantages include safety with no radiation, portability, accessibility, high resolution and a relatively lower cost.
Following the ultrasound studies of the lower leg muscle compartments in the early eighties and the method described by Van Holsbeeck et al , there was no further literature published on the use of ultrasound in the evaluation of CECS.
The majority of the early patients were referred to exclude other pathology and not specifically to confirm CECS. The ultrasound examinations reviewed in this study were retrospective and not conducted in a strictly standardised or 'scientific' fashion but they followed closely the described technique of Van Holsbeeck, hence are representative of the clinical situation.
The authors believed it reasonable to deviate from a prescribed exercise protocol as used in previous studies. The production of symptoms varied between individuals, hence it was deemed appropriate to allow each individual to exercise to the point of reproducing the symptoms. The effect of the differences of each exercise regimen may have had an impact but this was not assessed.
That 18 of the 34 patients were shown to be positive for CECS and responded well to surgery is suggestive that ultrasound may be a valuable tool in the diagnosis of this condition. This is further suggested by the outcome of the 16 patients who had a negative test, of whom ten were treated conservatively with good results. The fate of the untraceable patients in this study is not known and problematic.
Although thickening or rigidity of the interosseous membrane or fascia was not seen in this study as reported by Van Holsbeeck et al it is possible that the chronicity of the patients in the study by Van Holsbeeck differed from the patients in our study.
This review of cases has several weaknesses. Being retrospective it was not a welldesigned scientific trial. The clinical history was not documented; only the percentage increase in dimension of the muscle compartment was noted in the report and not the exact measurements; no comparison with normal athletes or nonathletes was made; and there were no controls. With respect to the outcomes, the lack of controls leads to the possibility of false conclusions. The result of the statistical analysis is not of any value due to the fact that 29.4% of patients could not be contacted and treatment received and success thereof is unknown.
At present invasive IMP measurement is still considered the gold standard for diagnosing CECS despite the fact that a standard reproducible protocol for IMP measurement has not been described. The main role of ultrasound in the investigation of patients with the clinical diagnoses of CECS is to exclude other pathology. This retrospective case review shows some promise that ultrasound may be of value as a non-invasive investigation complementing IMP measurement, but prospective controlled trials are needed to evaluate its role in the assessment of CECS.
The content of this article is the sole work of the authors. No benefits of any form have been derived from any commercial party related directly or indirectly to the subject of this article.
1. Hislop M, Tierney P. Intracompartmental pressure testing: results of an International survey of current clinical practice, highlighting the need for Standardized protocols. Br J Sports Med 2011;45:956-58. [ Links ]
2. Van Holsbeeck MT, Introcaso JH. Musculoskeletal Ultrasound 2nd ed.2001; 52-56. [ Links ]
3. Wasilewski SA, Asdourian PL. Bilateral chronic exertional compartment syndrome of the forearm. Clin Sports Med. 1992 Jan;11(1):161-88. [ Links ]
4. Gracia Mata S, Hidalgo OA, Martinez GM. Bilateral, chronic exertional compartment syndrome of the forearm in two brothers. Clin J Sport Med. 1999 Apr;9(2):91-99. [ Links ]
5. Gershuni DH, Gosink BB, Hargens AR, et al. Ultrasound Evaluation of the Anterior Musculofascial Compartment of the Leg Following Exercise. Clin Orthop Relat Res. 1982;167:185-90. [ Links ]
6. Martens MA, Backaert M, Vermaut G, Mulier JC. Chronic leg pain in athletes due to a recurrent compartment syndrome. Am J Sport Med.1984;12(2)148-58. [ Links ]
7. Garabekyan T, Murphey GC, Brandon R, et al. New noninvasive ultrasound technique for monitoring perfusion pressure in a porcine model of acute compartment syndrome. J Orthop Trauma.2009;23(3):186-194. [ Links ]
8. Hutchinson M. Chronic exertional compartment syndrome. Br J Sports Med 2011;45:952-53. [ Links ]
9. Hislop M, Batt ME. Chronic exertional compartment syndrome testing: a minimalist approach. Br J Sports Med 2011;45:954-955. [ Links ]
10. Wieman JM, Ueno T, Leek Bt, et al. Noninvasive measurements of intramuscular pressure using pulsed phase-locked loop ultrasound for detecting compartment syndrome: a preliminary report. J Orthop Trauma. 2006;20:458-63. [ Links ]
11. Brahim F, Zaccardelli W. Ultrasound measurement of the anterior leg compartment. Am J Sport Med.1986;14(4)300-302. [ Links ]
12. Lynch JE, Heyman JS, Hargens AR. Ultrasonic device for the noninvasive diagnosis of compartment syndrome. Physiol Meas..2004;25:N1-N8. [ Links ]
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Massachusetts Again Leads List of Most Energy-Efficient States
For the second consecutive year, Massachusetts has topped a prominent ranking of states' energy efficiency efforts.
The 2012 State Energy Efficiency Scorecard, which is compiled by the American Council for an Energy-Efficient Economy, placed California in the No. 2 slot. California had ranked No. 1 in the first four scorecards from the ACEEE before being toppled by Massachusetts last year.
The top ten also includes New York, Oregon, Vermont, Connecticut, Rhode Island, Washington, Maryland and Minnesota — the same ten states that made up the top tier in 2011, as well.
The ACEEE measures six primary policy areas thattypically pursue energy efficiency, including utilities, transportation, building codes, heat and power policies, government-led energy-efficiency initiatives, and appliance standards
Massachusetts continues to benefit from the effects of its Green Communities Act of 2008, which encouraged bigger investments in energy efficient programs by requiring utilities to save a growing percentage of energy each yearwith efficiency measures.
"We are proud to have maintained the number one spot in the nation because of our continued focus on innovation and investments in energy efficiency," said Massachusetts Gov. Deval Patrick, in a statement. "Our Green Communities Act is cutting our dependence on imported energy sources, creating jobs, and leading the way to a more sustainable energy future for Massachusetts."
The states that saw the most improvement last year were Oklahoma, Montana, and South Carolina — all of which gave their budgets for electric energy efficiency programs a boost in 2011, and saved even more energy from programs they kicked off in 2010 and 2009.
The scorecard also found that annual savings from customer-funded energy efficiency programs in 2010 were roughly equivalent to the amount of electricity the entire state of Wyoming uses each year — a 40 percent increase over a year earlier.
There were 21 states that fell in the rankings, with Maine dropping the furthest, by 13 places, and Nevada by nine. The ACEEE said that was due both to changes in its scoring methodology, and relatively faster progress by competing states.
The ten least efficient states were Nebraska, Louisiana, Missouri, Kansas, Alaska, South Dakota, Wyoming, West Virginia, North Dakota, and Mississippi, which ranked last.North Dakota was ranked last in 2011. The report said small improvements in energy efficiency have a big impact on a state's rankings, so those that don't ramp up their efforts will quickly fall behind.
The ACEEE said that even top-ranked states like Massachusetts should continue to make improvements, as no state achieved a perfect score. Among the group's recommendations were adopting and adequately funding an Energy Efficiency Resource Standard, or energy savings target, and putting in place tougher tailpipe emissions standards for cars and trucks, as several of the most energy-efficient states have done.

subset: commoncrawl


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Apple's streaming music service now has 38 million paid subscribers, up from 36 million in February, the company said on Monday.
Apple is locked in race for subscribers with Amazon.com, Alphabet's Google and others as streaming music becomes the dominant form of paid music consumption. Apple's number compares to 71 million premium subscribers at the end of 2017 at industry leader Spotify, which plans to list shares in the coming weeks on the New York Stock Exchange under the ticker symbol SPOT.
Apple said Eddy Cue, senior vice president of Internet software and services, disclosed the most recent subscriber number for Apple Music at the South by Southwest festival in Austin, Texas.
Amazon Music Unlimited has 16 million paying subscribers, and Pandora Media has 5.48 million total subscribers. Google does not release paid subscriber numbers for its service, Google Play Music.
Apple, Spotify, Google and other services charge $9.99 (roughly Rs. 650) a month for music. Amazon offers its service to members who already pay for its Prime membership, which includes shipping, video content and other benefits, for $7.99 per month.
In addition to its paid service, Spotify also offers an free ad-supported version to help draw users into the service. Apple Music does not offer an ad-based version and instead uses a three-month free trial to lure customers. Cue said Apple has 8 million subscribers currently in the free trial period, the first time Apple has disclosed the number of trial users.


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Posted on 21 February 2012 by James Gentry
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Posted on 08 July 2011 by James Gentry
The Luyas head out on Tour with The Dodos on a North American tour that starts August 26. You can also catch them in Montreal for the Osheaga Music Festival the end of July. Check out their video for "Too Beautiful To Work below".
Directed By: Derrick Belcham
Produced By: A Story Told Well / Dead Oceans
Art Direction: Ruby Kato Attwood
Lighting Design: Alana Ruth, Derrick Belcham, Ruby Kato Attwood and Jessie Stein
Production Design: Ruby Kato Attwood
Special Thanks To: Sarah Neufeld, Colin Stetson, Carl Spidla, Rachel Elliot, Sahra Campbell
The Luyas Are:
Jessie Stein
Pietro Amato
Stefan Schneider
Matthieu Charbonneau
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Posted on 26 January 2011 by James Gentry
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'We're going to remember this like it was the first night of Art Basel," Ocean Drive editor-in-chief Suzy Buckley Woodward said on Thursday night and she had a point.
She had just wrapped her magazine's party at the W South Beach with cover girl Chelsea Tyler, and Chrissy Teigen was still holding court there. And when Buckley Woodward walked us back to the SLS South Beach, the short five-block stroll took around 30 minutes. Not because of anybody's high heels, but because she kept running into people on the street, including shoe designer Donald Pliner.
Art Basel doesn't start until Dec. 6 in Miami, but South Beach's social scene was in full force Thursday, with a jammed crowd of moguls, models and misfits, many who had flown in for the day, partying the night away at SBE Entertainment Group's SLS South Beach grand opening.
LA-based SBE king Sam Nazarian was there, of course, posing with collaborators including starchitect Philippe Starck, Lenny Kravitz (the musician-turned-hotel-designer created the SLS' penthouse suite) and chef José Andrés. All the public spaces in the hotel were overflowing. Katsuya was filled with skinny minis and hungry men, including "Girls Gone Wild" boss Joe Francis, who stacked plates high with sushi. After Rumer Willis performed on an outdoor stage, Hyde Beach turned into what was billed as a "sexy hell," where a diverse cluster of pretty faces raged, dancing like there was no place to go tomorrow even though they had spin or pilates classes in about six hours.
And Andrés was his usual jolly self, offering up what seemed like an unlimited amount of what he calls "Jose's Tacos": Iberico ham topped with caviar at his playful as ever Bazaar restaurant, where it seemed like nobody had an empty cocktail or champagne glass.
It felt even odder than usual, this level of extreme decadence that always feels a bit odd. But this time, this was a room where New Yorkers talked about the perhaps irreparable hurricane damage to their homes and what was left unsaid was that there were people here who have NYC buildings where residents have been displaced.
But, of course, Andrés, who's also getting ready to unveil a food truck at SLS, was just doing what he gets paid to do. He was working, celebrating food, being the life of the bash, serving dishes that he knows are over the top because that's a big part of the point. That's his job. The crowd of Miami glitterati (Reggie Bush, Emilio Estefan, "Real Housewives" including Lea Black and Lisa Hochstein, Heat owner Micky Arison, real estate heavyweights Jorge Perez, David Edelstein and Edgardo Defortuna) got dressed up for a big night out, and Andrés was there to make sure they left happy.
And Andrés is also the man behind World Central Kitchen, an organization devoted to finding "sustainable solutions to ending food insecurity and malnutrition." Earlier last week, he was in Staten Island and the Rockaways, visiting Red Cross kitchens, "taking notes, asking questions and learning" all he could about New York's relief efforts. He was also tweeting up a storm to his 135,000-plus followers, telling them what they could do to help out all over the city even though he doesn't even yet have a New York restaurant.
But there's a good chance he will in the near future. Nazarian's opening an SLS on Park Avenue next year, and he's had serious talks with Andrés about joining him. Expect one hell of a big party.
Chef Andrew Carmellini's the Dutch at W South Beach has joined forces with Cobaya — Gourmet Guinea Pigs (a group that does Miami events inspired by "underground dinner clubs") on a Hurricane Sandy-relief fundraiser that's taking place Sunday, Nov. 18. The $250 five-course extravaganza will feature food from Miami chefs including Michelle Bernstein, Aaron Brooks and Jeremiah Bullfrog, with cocktails from the BarLab (a k a Broken Shaker) team that's working with Bullfrog on Miami's hip new Freehand youth hostel. All proceeds benefit NYC Food Flood, a relief fund started by Carmellini, Marco Canora, Seamus Mullen and George Mendes. To request seats, e-mail email@example.com
Follow Andy Wang at twitter.com/andywangny.


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On June 10th, the Pope's Wednesday general audience continued his catecheses on the family, focusing on the theme of sickness and suffering. Man experiences his own fragility primarily in the family, first as a child and, then, as an elderly person.While family sickness presents obvious challenges, it can also be a source of quiet strength and deepening of faith.
Pope Francis stresses that we must " educate children as little ones to solidarity in the time of sickness:
The sickness of persons we love is endured with 'more' suffering and anguish. It is love that makes us feel this 'more'. So often it is more difficult for a father and a mother to endure the sickness of a son, of a daughter than their own. The family, we can say, has always been the closest "hospital." Even today, in many parts of the world, the hospital is a privilege for a few, and it is often far away. It is the mother, the father, brothers, sisters and grandparents that guarantee care and help to heal.
Contrary to contemporary society which tends to recoil from sickness, the pope understands the "weakness and suffering of loved ones can be, for our children and our grandchildren, a school of life". An "education that lacks sensitivity for human sickness hardens the heart." Obviously, Catholics, must learn not to shelter our children from suffering because it is an integral part of our faith. Cardinal Gianfranco Ravasi's sheds light on the pope's teaching when he said there is "an unavoidable spiritual dimension to illness for us Christians because "ours is a religion of the flesh."
During this catechesis, the pope turned to the Gospels pointing to Jesus who did not avoid suffering but rather embraced and cared for the sick. Christ "presents himself publicly as one who fights against sickness and who has come to cure man of every ill: ills of the spirit and of the body." The Pope points to the scene in the Gospel of Mark:
"that evening at sundown they brought to him all who were sick or oppressed by demons" – is "truly moving … Jesus never withdrew from their care, He never passed them by, He never turned away. And when a father or a mother, or even simply friends brought an invalid before Him, for Him to touch and heal, He wasted no time; healing came before the law, even sacred laws such as rest on the Sabbath."
Jesus healed all who reached out to Him in faith and He sent His disciples out to preach, giving them the power to heal just as He did. "See God's glory! See the task of the Church! To help the sick, not to get lost in chatter, but to help always, to console, to relieve, to be close to the sick; this is the task".
Of course, today all sickness of the flesh is not healed but Pope Francis points out prayer heals and strengthens the spirit of those who are ill as well as family members. Emmanuel Mounier, the French philosopher (1905-1950), illustrates the pope's teaching. He had an infant daughter who was hospitalized with a serious brain condition, "What sense would all this make if our baby was only a diseased flesh, a piece of life in pain, and not a small white wafer that is beyond us all, an infinity of mystery and love which would dazzle us were we to see it face-to-face?," he asked. We are spirit as well as flesh. With faith and prayer, illness can bring us closer to each other and God, healing our spirits.
"The Church invites us to continual prayer for our dear ones who are sick, and prayer for them must never be lacking. Rather, we must pray more, both personally and as a community. … Faced with sickness, difficulties can also arise in the family as a result of human weakness. But in general illness strengthens family bonds. And I think of how important it is to educate children, starting from infancy, on the importance of solidarity in times of sickness. An education that shelters them from sensitivity to human sickness hardens the heart and anaesthetises the young to the suffering of others, rendering them incapable of facing up to suffering and living the experience of limits."
Catholic families must learn to follow Christ's attitude, forming children who can face up to suffering.
"The weakness and suffering of our most loved ones … can be … a school of life … and especially when illness is accompanied by prayer and the fraternal, affectionate closeness of families. The Christian community is well aware that the family, during the trials of sickness, must not be left alone. … This Christian closeness of family to family, is a true treasure for a parish: a treasure of wisdom, that helps families in difficult moments and enables them to understand the Kingdom of God more clearly than through words."


text:
Tuesday, August 13, 2013
A Flock of Flying Geese Quilt II
32 comments:
Oh my it's lovely! How on earth do you create these beautiful quilts so quickly?! :)ReplyDelete
Oh I really love this quilt. It is so pretty and vibrant in color. When grid quilting what size stitch do you use?ReplyDelete
It's gorgeous Rita. I'm also a pin baster, and I pin on my mum's tile floor :)ReplyDelete
Beautiful! I'm new to quilting and has just been learning about making bias tape:) i'm rather curious about your stripes binding... Is it not cut crossgrain when you made the tape? :DReplyDelete
I just love it. I get tickled when you mix in the vintage fabrics. Thanks for sharing your methods too. I'm in awe of all those pins. I've never pin-basted.ReplyDelete
Definitely a beautiful quilt, Rita. I love that tiny grid, but I do not want to attempt it. Straight lines are not my forte! Question: how do you get off the floor after pin basting? lol Obviously I'm the older of us because I can't get of the floor!ReplyDelete
I've said it before and I'm sure I'll say it again, but periodically I just have to pop in and say: you are a master seamstress. I am not a perfectionist myself but you bet I enjoy ogling your PERFECT workmanship. Absolutely stunning!ReplyDelete
I love it! Perhaps you need to quilt yourself some knee pads? I am yet to baste my very first quilt because I dread the idea if crawling around on the floor and I have carpet!ReplyDelete
Wow! Lots of pins. Obviously you put a lot of patient attention into your quilts. And it shows! It's lovely, Rita!ReplyDelete
Beautiful quilt, I'm always amazed at how quickly you make such perfect quilts.ReplyDelete
My husband bought me some amazing Burgon Ball knee pads which have taken the agony out of crawling on the hard wooden floors. :)
Love your quilting and am in awe of how perfect your quilts always look. I am straight lining a quilt at the moment and it has gone all wonky, despite thinking I had basted it really well. Seam ripper time for me :(ReplyDelete
gorgeous, as always! i especially love the four geese with the white centers and the kaffe print.ReplyDelete
I'm going to give pin basting a go next time rather than stitch basting.ReplyDelete
Your quilt looks fantastic.ReplyDelete
Lovely work as usual. When you purchase fabric, is there a certain amount that you have in mind to buy or is it always different? As well, any chance of ever seeing your fabric stash as a whole? Thank you for being such an inspiration.ReplyDelete
Lovely work as usual. When you purchase fabric, is there a certain amount that you have in mind to buy or is it always different? As well, any chance of ever seeing your fabric stash as a whole? Thank you for being such an inspiration.ReplyDelete
Another lovely finish, Rita! It is always a pleasure to see your work. If you ever find yourself looking for another option, rather than crawling on the floor, please consider this suggestion... http://sewfreshquilts.blogspot.ca/2013/03/sew-retro-baby-quilting.htmlReplyDelete
I have never had an issue with puckering. Hope you find this useful!
I love this quilt. Why don't you buy a smallish boardroom table and do all the basting etc. on it. I bought one years ago - cheaply, and can baste (I sit and thread baste as I like the motion and feeling the quilt build) and can do sections at a time taping it down. I can do up to a queen size this way and quilt on my home Bernina with ease. Getting down on the floor is a super big drag and gets harder with each passing year.ReplyDelete
Love this quilt and the quilting.... YUM-YUM!ReplyDelete
Thank you for sharing Rita! You are so generous with your knowledge. It hadn't occurred to me to tape the batting as well - I am going to try it - I often use more than one layer of batting and it can be difficult to keep it nice and tight. Thank you for the tip!ReplyDelete
you make such beautiful simple happy quilts! love the backing! xxReplyDelete
A tip I learned for basting on the floor - find either tiler knee pads (the velcro around your knees) or gardener's kneeling pads. They save your knees, your back is another story....ReplyDelete
The quilt is lovely! No crawling on the floor pin basting for me - I have a custom table that can be 4' x 8', 6' x 8', or with both leaves open 8' x 8'. Several of the women in my quilt group have come over to baste their quilts on my table so they didn't have to crawl on the floor. The table was worth every dime I paid for it!ReplyDelete
- AnonymousAugust 15, 2013 2:20 AM
Absolutely amazing, as always. You do such beautiful work. Best to you, SondraReplyDelete
Love your quilt. Do you always pin baste in the seam area? Also - what type/weight of thread do you use to machine quilt it? And then what needle size with it? Also what is your stitch length. thanks so much for your help in trying to help the rest of us improve on our quilting ;)ReplyDelete
Great quilt! What a lovely mixture of old & new fabrics!! I tend to start pinning from the centre & work in 1/4 sections over the whole quilt...and I also pin baste it all by crawling over the floor! Linda NZ email@example.com
This is so beautiful. Flying geese give this such movement and as always your fabric choices are perfection, along with the backing and binding fabric.ReplyDelete
I was wanting to ask to I know you are busy but do you sew all one direction up and down then turn the whole thing and go the other way thanks dianaReplyDelete
a glorious quilt Rita!ReplyDelete
I love your quilts! How much fabric do you usually buy? You always seem to have enough for your backs. Thanks!ReplyDelete
That seems like a perfect amount of pins to me. The better you pin baste the less likely you are to have any puckers.ReplyDelete
I love this quilt! The quilting looks amazing, I really like the grid pattern!ReplyDelete
Thank you for stopping by and leaving a comment! I really appreciate it.
Comments are published after review.
Feel free to ask questions and I will answer either here or by email, as is appropriate.


text:
|This photo doesn't do justice to the fervor and noise with which
those geese approached. I'll be honest- I got a little nervous!
|Eyes closed, John. Closed.
|Can't do that with a normal belly, can you?
|This photo doesn't do justice to the fervor and noise with which
those geese approached. I'll be honest- I got a little nervous!
|Eyes closed, John. Closed.
|Can't do that with a normal belly, can you?
I LOVED the maternity shoot!! How creative! The pics turned out great--way to go dad! :) Congrats on the good news!!ReplyDelete
These are great! :) I especially love the pictures with the globe. What a wonderful idea!ReplyDelete
What an amazing idea, and these pictures are beautiful.ReplyDelete
Love it! We have planned on doing something similar once we get a little closer to our baby. I was originally inspired by these photos:
Wow, those are awesome! And, I love, love, love that link right above my comment, too.ReplyDelete
my friend, jen, shared this post with me. so sweet! congratulations on this hard, but blessed journey!ReplyDelete
Fabulous pictures!
You don't know me, but I'm a friend of Sara Hogan's. I've been reading your blog and I've nominated you for the Liebster Blog Award! Congratulations! It's an award that goes to fabulous blogs with fewer than 200 followers. It's kind of like a chain letter, so what you have to do in order to receive it is this: 1) Put the Liebster blog image in your post, 2) link to the blog that nominated you, 3) tell 5 fascinating things about yourself, 4) nominate and link to 4-6 other blogs and 5) send them a comment to let them know you nominated them. Congratulations! I'm so excited for your family!
Oh my gosh these are adorable! I wish I'd thought of this when we were adopting.
So beautiful. Best of luck,ReplyDelete
Saw these on Pinterest... I love the globe one so very much! Just precious!ReplyDelete
This is such an awesome idea! I found your picture on Pinterest. Love it! I wish we would have done this with our daughter from Ethiopia.ReplyDelete
I found this on Pinterest and love it! My husband and i are just now in the beginning stages of our adoption home study. I can't wait to use some of our ideas for our Christmas card this year!ReplyDelete
I also found youre pictures on Pinterest. Love them! Good luck!ReplyDelete
Would love to follow your journey. Congrats.ReplyDelete
Love pics. Would love to knOw how journey is unfolding... Blessings.ReplyDelete
Beautiful! My husband and I have adopted twice. I wish we had done this. :)ReplyDelete
Beautiful! My husband and I have adopted two children. I wish we had thought to do this. :)ReplyDelete
Love love love!! Congratulations!!ReplyDelete
Absolutely love these ideas! Too Cute! My hubby and I are on our beginning stages of adopting a child from Bulgaria. Your blog is so wonderful! God Bless and Congratulations on your adorable son.ReplyDelete
I love this! Hubster and I have been looking to adopt. I love the globes ones, but we were trying to adopt locally.ReplyDelete
beatifull, lovely ... :)ReplyDelete


text:
DARRINGTON — One day in early March, Francine Hatley stood on the ground floor of this old logging town's original City Hall building. She was surrounded by furniture, moulding awaiting installation, tools and plywood.
Behind a partly finished separating wall, more tools, lumber, burners and kegs of homemade beer in chest freezers.
For the first time in more than a decade, the old Darrington City Hall building, which dates to the 1940s, is getting a tenant.
Whiskey Ridge Brewing Co. is opening for business in the next couple of weeks, with just a few permits to be obtained.
The new brewery and taproom — a first for this old logging town, at least in recent memory — is more than just a business. It's a labor of love for Francine and especially her husband and brewmaster, Jack Hatley.
"My husband needed a hobby," she said, by way of explaining the brewery's origins.
Francine was an avid martial artist, but she couldn't get Jack interested.
What he did like, however, was craft beer. One Christmas about eight years ago, she surprised him with a home brewing kit.
The first few batches weren't all that great, Jack Hatley said.
"I did a couple of extract batches before I started putting together a kit with whole grains," he said.
Francine described coming home from work one day to find a lot more equipment had been moved into the garage.
The all-grain batches turned out better, but the continuing adventure in brewing was not without mishaps.
One morning Francine found the garage ceiling and walls stained because one of the batches had blown its top overnight.
Another day, she entered the garage and smelled singed fur. Their black Labrador-mastiff mix, Toby, who was Jack's constant brewing buddy, had gotten too close to one of the burners.
(Toby, who died last fall, is still the official mascot of Whiskey Ridge, and will lend his image to the future label for their Dead Dog Rising Oatmeal Stout when the Hatleys start bottling it.)
With friends encouraging them to sell their beer, the Hatleys embarked on the quest to open a brewery.
They found the red tape associated with opening a business in Marysville, where they live, to be too onerous, however, and so they looked farther afield.
"The city of Darrington has pretty much bent over backward to accommodate us," she said.
Bruce Blacker, the owner of Wild Edge Woods sawmill in nearby Oso, had leased the City Hall building, at 650 S. Emens St., from the city for $1,000 a year. He wanted to put a brewery on the ground floor, open a brewpub with a full food menu in the spacious upstairs room, and practice his own hobby, distilling vodka and rum, in the basement.
He was willing to rent the ground floor to the Hatleys for dirt cheap.
"The whole idea was to get the city of Darrington some kind of business in there that would draw visitors," Blacker said.
The Hatleys are operating on a shoestring budget. Equipment and furnishings they found used, or they were donated. Francine Hatley said she and Jack had only used their savings and some money borrowed from his retirement fund at his day job with an aerospace company. No credit cards or other loans.
As is sometimes the case in Darrington, the Hatleys' startup has turned into a bit of a community project. Blacker himself came in and installed of the walls while the Hatleys and their three sons did another one — they'd had to tear out all the old drywall and insulation because of mold.
Electrical and plumbing contractors agreed to staggered payments. Even the town's mayor, Dan Rankin, came in and installed the ceiling to the walk-in cooler.
The result is still rough-and-tumble, as befits a shoestring operation.
One setback they had is that the compressor they got for free for a walk-in cooler turned out to be for outdoor use only, so they instead turned their planned cooler into a storage room with plug-in coolers and chest freezers.
Elsewhere the Hatleys are still working to get things ready. The floor is still unpolished concrete, and the walls haven't been painted yet.
"It doesn't have to be pretty. It will be clean and functional, though," Francine said.
They'll maintain a family-friendly atmosphere. Customers will be encouraged to bring in food to eat along with their beer. Whiteboards on the walls are for messages, recipe ideas, doodles or whatever strikes the customers' fancy.
The Hatleys hope to have eight taps going by the time summer arrives, reasoning a cold pint will be just the refresher for hikers coming down off Whitehorse Mountain.
"Once we've been in business for a while we can start upgrading things," she said.
Blacker, for his part, put his distillery plan on hold because his sawmill is busy suppling the wood for the "Treehouse Masters" show on the Animal Planet network.
But he thinks Whiskey Ridge Brewing could be successful.
"They should do well all through the summer," Blacker said. "Winter is always hard up there when the pass closes."
For now, with opening day looming, the Hatleys are just glad that a long-running dream is finally turning into reality.
Looking around the still-cluttered taproom, Francine smiled.
"It's a welcome change to get this equipment out of my garage," she said.
Chris Winters: 425-374-4615; firstname.lastname@example.com.
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Rule #1 - Be Patient - Rule #2 - Don't ask when, if you don't contribute - Rule #3 - You have coding skills - LinuxMCE's small brother is available: http://www.agocontrol.com
Hello,I am trying to utilize an Nokia n800 as a remote for LMCE. Unfortunately, it does not seem to work within the VDR part of LMCE. I see a remote, but NONE of the keys on the display of the n800 work. Anyone else experiencing the same problem? Am I doing something wrong?Any and all help is greatly appreciated.rgdsOliver


text:
Watch One World Trade Center Rise from the Ashes Beam by Beam
EarthCam has been monitoring the construction of One World Trade Center (BKA the Freedom Tower) since day one: October 18th, 2004. (Technically, the cornerstone ceremony took place July 4, 2004, and construction didn't begin in earnest until 2006.)
Yesterday, the skyscraper officially became the tallest building in New York*, and, to celebrate that symbolic milestone, EarthCam released an abbreviated time-lapse video of all the footage it has collected over the past eight years.


text:
When Microsoft set out to build Windows 10, the company had a challenge to face: The operating system needed to appeal to the wide swath of people already using Windows.
"We joke on our team that we're ordering pizza for one-and-a-half billion people," Mohammed Samji, a principal group program manager at Microsoft, said in an interview.
In order to serve all of those users, Microsoft wanted Windows 10 to work well for people no matter what interface they chose. Windows 8 was criticized by people who thought that Microsoft had moved too much functionality around in order to accommodate and appeal to users of tablets. The company walked back some of the changes with its release of Windows 8.1, but this new update is designed to appeal further to traditional keyboard and mouse users alongside owners of touch devices.
Check out all of PCWorld's Windows 10 coverage
To facilitate that, Microsoft has been working with outside stakeholders on the operating system since January 2014, when the company approached some of its enterprise customers to begin discussing Windows 10 under the cover of non-disclosure agreements. Since then, the company opened up the Windows Insider Program, which allowed anyone to pick up a pre-release version of the operating system for testing purposes. Feedback from those people has translated into tweaks to Windows 10.
"We've actually changed the plan," Samji said. "We've added things, we've removed things based on the feedback from our 5 million best friends that are actually testing the product for us."
There are now 5 million Windows Insiders, and their feedback has helped shape the operating system's direction. Thanks to changes made based on feedback from Insiders, the operating system features more translucent elements similar to Windows 7's Aero Glass, and Microsoft's new Edge browser includes a dark theme.
Overall, Samji said that Windows 10 should feature something for everyone, including an interface that works well whether people are using a mouse and keyboard, a touchscreen, or some combination of the two. The operating system's interface actually changes itself for different modes of interaction, which is important for increasingly popular 2-in-1 devices that can behave like both a laptop or tablet.
Reviews of Windows 10 appear mostly favorable thus far, which is a positive sign for Microsoft's initial efforts.
Of course, it remains to be seen whether users will take to the new operating system. Microsoft is hoping that there will be 1 billion devices running Windows 10 within three years. Wednesday marks the first day the operating system is officially available for consumers, and it will be interesting to see how many of them hop on board.


text: Apple CEO Tim Cook is having a good week.Cook attended the State of the Union address as a guest of First Lady Michelle Obama and got a verbal fist-bump from the President. Earlier in the day, he spoke at the Goldman Sachs Internet and Technology Conference, where topics ranged from affordable product pricing to Prozac. It's about time Cook basked in a little glory. After all, he's had a bad run recently, helplessly watching Apple's stock slide while delivering the earnings report last month. Clearly, Wall Street no longer sees Apple as a high-growth company and casts doubt about its ability to innovate. At the Goldman Sachs conference, Cook said Apple will make products more affordable. It's an about-face to Apple's tradition of high-end, premium-priced products. Rather than making a cheap product, though, Cook referred to Apple's practice of dramatically discounting older models whenever a new model hits the market. "We are making moves to make things more affordable," Cook said. "Instead of saying how we can cheapen this iPod to get it lower, we said how can we do a great product, and we were able to do that\u2014the same thing, but in a different concept in some ways." This is important for CIOs, because older Apple models play well in the enterprise. For instance, retailer Home Depot recently told Apple Insider that it plans to displace some 10,000 BlackBerry smartphones for iPhone 4S devices, not iPhone 5s. (A Home Depot spokesperson confirmed the switch but declined to give details, only to clarify that the switched smartphones are not ones used in stores.) Interestingly, Cook said his team couldn't build a cheaper Mac without sacrificing quality, but a new form factor such as the iPad solves the problem. In a research note, Piper Jaffray analyst Gene Muster suggested the rumored iWatch could do the same for the iPhone in emerging markets. On the lighter side, Cook joked that whenever his energy droops, he recharges by going shopping at an Apple store. Of course, it's doubtful that he actually buys anything. "If I ever feel like I'm dropping down to a level that's below excited, I go to the Apple Store," he said. "It's like a Prozac!" Slideshow: Apple Innovation: 10 Future Tech IdeasLater that day, Cook attended the State of the Union address. At one point, President Barack Obama's speech turned to the return of U.S. manufacturing. "This year, Apple will start making Macs in America," President Obama said, and television cameras turned to a beaming Cook. Of course, Apple's "Macs in America" gesture late last year sounds like a marketing ploy. After all, they're probably iMacs. Apple's $100 million U.S. manufacturing investment is a paltry sum relative to its $120 billion cash on hand. But it bought Cook and Apple some good press at the State of the Union address.\nNevertheless, Cook's appearances this week are a good rebuttal to Apple's sagging image. Tom Kaneshige covers Apple, BYOD and Consumerization of IT for CIO.com. Follow Tom on Twitter @kaneshige. Follow everything from CIO.com on Twitter @CIOonline, Facebook, Google + and LinkedIn. Email Tom at email@example.com


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TARPON SPRINGS, Fla. (AP) — A church in Tarpon Springs is closed indefinitely following the discovery of two sinkholes on the property.
The Tampa Bay Times reports (http://bit.ly/19NYOFR) that the Unitarian Universalist Church of Tarpon Springs discovered the sinkholes while remodeling.
The 80-member congregation is meeting instead at an Elks Lodge. Rev. Don Rollins says the total damage is still being calculated, but it might be as much as $1 million.
The church building is more than a century old. It is known for its paintings in the sanctuary.
A famous early 20th century artist named George Inness Jr. was a member, and his paintings adorn the sanctuary. They're undamaged, but until the engineers sign off and allow people back inside the church, the valuable paintings are off-limits.
Source: Associated Press


text:
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Presents Openwork Photo Christmas Ornament
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A personalized Presents Openwork Photo Christmas Ornament is the perfect way to decorate your Christmas tree and is an ideal keepsake for remembering all of your favorite moments. This ceramic photo ornament can be customized using two different photos, a photo and text and can hang anywhere on the tree. Upload a photo of your choice, taken on your annual summer vacation, your honeymoon, or any other cherished moment. No matter where your photos are - on your phone or on your desktop, upload them for a high quality product. This openwork ornament comes with a delicate, beautiful cutout outer edge. Create one for grandparents, friends, out of town family members and don't forget to get one for your own tree.
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Author and Curator: Ritu Saxena, Ph.D
Although cancer stem cells constitute only a small percentage of the tumor burden, their self-renewal capacity and possible link with recurrence of cancer post treatment makes them a sought after therapeutic target in cancer. The post on cancer stem cells published on the 22nd of March, 2013, describes the identity of CSCs, their functional characteristics, possible cell of origin and biomarkers. This post focuses on the therapeutic potential of CSCs, their resistance to conventional anti-tumor therapies and current therapeutic targets including biomarkers, signaling pathways and niches.
CSCs Are Resistant to conventional anticancer therapies including chemotherapy, radiotherapy and surgery that are used either alone or in combination. However, these strategies have failed several times to eradicate CSCs resulting in metastasis and relapse, hence, a fatal disease outcome.
The properties of CSCs that contribute to or lead to chemoresistance include:
Quiescent Phenotype
Chemotherapeutic agents target fast-growing cells; however, some CSCs that remain in the dormant or quiescent stage are spared from lethal damage. Later, when the dormant CSCs enter cell cycle, tumor proliferation is stimulated.
Antiapoptotic proteins such as BCL-2 and some self-renewal pathways such as transforming growth factor β, Wnt/ β -catenin or BMI-1 are activated in CSCs. Consequently, DNA damage repair capability of CSCs is enhanced after genotoxic stress or activation of autocrine loops through the production of growth factors like epidermal growth factor (Moserle L, Cancer Lett, 1 Feb 2010;288(1):1-9).
Expression of Drug Efflux Pumps
CSCs express some proteins that have typically been known to contribute to multidrug resistance. The proteins are drug efflux pumps ABCC1, ABCG2 or MDR1. Multidrug resistance-associated proteins (ABCC subfamily) are members of the ATP-binding cassette (ABC) superfamily of transport proteins and act as cellular efflux transporters for a wide variety of substrates, in particular glutathione, glucuronide and sulfate conjugates of diverse compounds.
Radiotherapy is mainly used in breast cancer and glioblastoma multiforme. In glioblastoma multiforme, the properties of CSCs that contribute to radiotherapy resistance is the presence of CD133 marker. CD133+ CSCs preferentially activate DNA damage repair pathway and significantly induced checkpoint kinases that leads to reduced apoptosis in CSCs compared to the CD133- tumor cells (Bao S, Nature, 7 Dec 2006;444(7120):756-60).
Radiotherapy resistance in breast cancer is due to reduced levels of reactive oxygen species in CSCs. In addition, radiation resistance of progenitor cells in an immortalized breast cancer cell line was mediated by the Wnt/β catenin pathway proteins (Diehn M, et al, Nature, 9 Apr 2009;458(7239):780-3; Chen MS, et al, J Cell Sci, 1 Feb 2007;120(Pt 3):468-77).
As mentioned in the previous post on CSCs, CSC targeting therapy could either eliminate CSCs by either killing them after differentiating them from other tumor population, and/or by disrupting their niche. Efficient eradication of CSCs may require the combined ablation of CSCs themselves and their niches. Thus, identification of appropriate and specific markers of CSCs is crucial for targeting them and preventing tumor relapse. Table 1 (adapted from a review article on CSCs by Zhao et al) describes the currently used biomarkers for CSC-targeted therapy (Zhao L, et al, Eur Surg Res, 2012;49(1):8-15).
Table 1
|Specific Target
|Cancer type
|Marker properties and therapy
|Targeting cell markers
|Pancreatic cancer
|Pancreatic CSCs, elevated during tumorigenesis
|Breast cancer
|Breast CSCs
|EpCAM high CD44+CD166+
|Colorectal cancer
|broad use as a target for chemotherapy
|Prostate cancer and breast cancer
|5-transmembrane domain cell surface glycoprotein,also a marker for neuron epithelial, hematopoietic and endothelialprogenitor cells
|Bone sarcoma
|Knockdown or pharmacological inhibition of its receptorAlk4/7 abrogated self-renewal capacity and in vivo tumorigenicity of CSCs.
|Targeting signaling pathways
|Hedgehog signaling
|Upregulated in several cancer types
|inhibitors: GDC-0449,PF04449913, BMS-833923, IPI-926 and TAK-441
|Wnt/β-catenin signaling
|CML, squamous cell carcinoma
|Be required for CSC self-renewal and tumor growthinhibitors: PRI-724, WIF-1 and telomerase
|Notch signaling
|Several cancer types
|An important regulator in normal development, adult stem cell maintenance,and tumorigenesis in multiple organs,inhibitors: RO4929097, BMS-906024, IPI-926 and MK0752
|Several cancer types
|The pathway is deregulated in many tumors and used to preferentially target CSCsinhibitors: temsirolimus, everolimus FDA-approved therapy for renal cell carcinoma
|Targeting CSC Niche
|Angiogenesis Niche
|Colon cancer, breast cancer, NSCLC
|Inhibitor: bevacizumab results in a disruption of the CSC niche, depleted vasculature and a dramatic reduction in the number of CSCs.
|Hypoxia (HIF pathway)
|Ovarian cancer, lung cancer, cervical cancer
|Inhibitors: topotecan and digoxin have been approved for ovarian, lung and cervical cancer
|Targeting Micro RNA
|miR-200 family
|Inhibits EMT and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
|Let-7 family
|Regulates BT-IC stem cell-like properties by silencing more than one target
|Related to neuronal differentiation, targets laminin γ1 and integrin β1.
|Suppresses the self-renewal of embryonic stem cells
The challenge is to develop an effective treatment regimen that prevents survival, self-renewal and differentiation of CSCs and also disturbs their niche without damaging normal stem cells. In order to evaluate the efficiency of CSC-targeting therapies, in vitro models and mouse xenotransplantation models have been used for preclinical studies. Some potential CSC targeting agents in preclinical stages include notch inhibitors for glioblastoma stem cells and telomerase peptide vaccination after chemoradiotherapy of non-small cell lung cancer stem cells Stem Cells (Hovinga KE, et al, Jun 2010;28(6):1019-29; Serrano D, Mol Cancer, 9 Aug 2011;10:96). In addition, several phase II and phase III trials are currently underway to test CSC-targeting drugs focusing on efficacy and safety of treatment.
Bao S, Nature, 7 Dec 2006;444(7120):756-60).
Diehn M, et al, Nature, 9 Apr 2009;458(7239):780-3
Chen MS, et al, J Cell Sci, 1 Feb 2007;120(Pt 3):468-77
Zhao L, et al, Eur Surg Res, 2012;49(1):8-15
Hovinga KE, et al, Jun 2010;28(6):1019-29
Serrano D, Mol Cancer, 9 Aug 2011;10:96
Pharmaceutical Intelligence posts:
http://pharmaceuticalintelligence.com/2013/03/22/in-focus-identity-of-cancer-stem-cells/ Author and curator: Ritu Saxena, PhD
http://pharmaceuticalintelligence.com/2012/08/15/to-die-or-not-to-die-time-and-order-of-combination-drugs-for-triple-negative-breast-cancer-cells-a-systems-level-analysis/ Authors: Anamika Sarkar, PhD and Ritu Saxena, PhD
http://pharmaceuticalintelligence.com/2013/03/07/the-importance-of-cancer-prevention-programs-new-perceptions-for-fighting-cancer/ Author: Ziv Raviv, PhD
http://pharmaceuticalintelligence.com/2013/03/03/treatment-for-metastatic-her2-breast-cancer/ Reporter: Larry H Bernstein, MD
http://pharmaceuticalintelligence.com/2013/03/02/recurrence-risk-for-breast-cancer/ Larry H Bernstein, MD
http://pharmaceuticalintelligence.com/2013/02/14/prostate-cancer-androgen-driven-pathomechanism-in-early-onset-forms-of-the-disease/ Curator: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/01/15/exploring-the-role-of-vitamin-c-in-cancer-therapy/ Curator: Ritu Saxena, PhD
http://pharmaceuticalintelligence.com/2013/01/12/harnessing-personalized-medicine-for-cancer-management-prospects-of-prevention-and-cure-opinions-of-cancer-scientific-leaders-httppharmaceuticalintelligence-com/ Curator: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/01/10/the-molecular-pathology-of-breast-cancer-progression/ Author and reporter: Tilda Barliya PhD
http://pharmaceuticalintelligence.com/2012/11/30/histone-deacetylase-inhibitors-induce-epithelial-to-mesenchymal-transition-in-prostate-cancer-cells/ Reporter and Curator: Stephen J. Williams, PhD
http://pharmaceuticalintelligence.com/2012/10/22/blood-vessel-generating-stem-cells-discovered/ Reporter: Ritu Saxena, PhD
http://pharmaceuticalintelligence.com/2012/10/17/stomach-cancer-subtypes-methylation-based-identified-by-singapore-led-team/ Reporter: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2012/09/17/natural-agents-for-prostate-cancer-bone-metastasis-treatment/ Reporter: Ritu Saxena, PhD
http://pharmaceuticalintelligence.com/2012/08/28/cardiovascular-outcomes-function-of-circulating-endothelial-progenitor-cells-cepcs-exploring-pharmaco-therapy-targeted-at-endogenous-augmentation-of-cepcs/ Aviva Lev-Ari, PhD, RN


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StudiosCentral has posted a new menu for Fairfax Fare, which includes: chicken, ribs, beef brisket, a chili hot dog, and more!
And, just in case you weren't aware, Fairfax Fare is also serving breakfast these days:
Who knew there was so much going on right down the street from the Tower of Terror?!


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Sign up now to stream Food Wars!, subs, tons of dubs, OVA's, simulcasts, plus the all new Dubcast℠ editions and more!
Another challenge is underway! Though, it's not official, and Soma soon discovers that an official challenge is something entirely different - it's a Food War.
Soma spends his days battling his father to see who the best chef at his family restaurant is. Things get complicated when a developer tries to muscle in on their land.
Soma goes up against a difficult foe, Erina Nakiri, owner of the "God's Tongue": her palate can literally make or break your career! Can a lowly diner chef pass her test?
Soma causes quite a stir at the opening ceremony, declaring his intentions to be #1. His first big obstacle: a world renowned french chef and an overly nervous teammate!
Soma arrives at Polar Star Dormitory with high expectations, but its shabby exterior houses talented chefs, an incredible kitchen and an unexpected challenge!
Another challenge is underway! Though, it's not official, and Soma soon discovers that an official challenge is something entirely different - it's a Food War.
Soma is drawn to the Rice Bowl Research Society, only to find that it's being threatened by Erina's lackey, Ikumi Mito, nicknamed the Meat Master.
The Food War between Ikumi Mito and Yukihira Soma has begun! Soma will have to truly transform his cheap ingredients to combat the Meat Master's expensive beef.
A brutal training camp is underway. Those in Polar Star Dorm are determined to survive, but Soma may have met his match - another professional!
Soma's fired up by Takumi Aldini's challenge and skills. With only the immediate vicinity as their pantry, Soma finds the perfect ingredient to set his dish apart.
Under the alumnus Shinomiya, Soma and Megumi are given a complex "recette" that they must follow to the letter. But Shinomiya is a cruel judge, and more severe than expected.
Soma's reckless streak flared up again and it's landed him and Megumi in hot water. Their opponent is no student this time, but a magician!
Megumi's come a long way on her cooking journey, and her future now rests in the hands of the judges. Will her dish be enough to save her?
The training camp lives up to its brutal reputation as the exhausted students are given two choices at the end of day three!
Soma's dish is literally deflating! It will take every ounce of his focus to get back on track, but it might be too late.
As the members of Polar Star Dormitory finally make it home, they're treated to a meal from a surprise guest, whose fame rattles even Soma.
Soma has his first showdown with his dad in months. With Isshiki, Megumi, and Fumio judging this morning match, will this finally be Soma's first victory?
Over the break, Yukihira challenges a popular fried chicken shop to save his old shopping district. He's found a taste tester, but who can he call to help develop the recipe?
Soma and his team work on a tasty, original and portable dish to combat the Mozuya invasion. They'll have to make their mark on the Sumire shopping district or watch it fall.
The lists for the Fall Selection are out! When the topic is announced, Soma seeks out a former colleague of his father's and finds more than he bargained for.
There's no summer break for the Fall Selection participants! Soma and the others work to enhance their dishes over the six weeks before they head into the prelims.
The Fall Selection preliminaries are underway! Megumi shocks everyone with a tricky ingredient, and the election hall is assaulted by "cursed" curry!
The prelims continue! Hoshino's curry is judged, and the Aldini brothers face off. In the wake of Alice Nakiri's dish, the judges make the mistake of almost forgetting Megumi.
With the finalists from Group B solidified, Group A is reeling as a judge continues to give zero points. Ryo Kurokiba, Alice's aide, presents a dish that surprises everyone.
Tensions mount as Soma faces off against Akira Hayama and the finalists are chosen!


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Chhabra 555 Made-to-Measure PInk Embellished Gown with Banarasi weaving and Zari Embroidered Dupatta
Color: Pink
Fabric: Silk Blend
Shape: Fit and Flare
Neck: Boat Neck
Hemline: Flared
Length: Maxi - 59 inches
Pattern: Flared
Pattern Type: Embellished
Surface Styling: Embroidered
Closure: Concealed Zip
Sleeve: Regular Sleeves
Has a lining
Dryclean Only
Made to Measure
Additional Notes:
We are proud to be 100% Made in India. We believe in supporting our local karigars and artisans and strive to make a better future together.
We believe in providing high quality products to make long term repeat customers. We take great pride in dressing up our third generation brides.
We offer international shipping as well as 100% return for domestic customers. Do reach out to us if you are looking for some customized services.
10% discount on your first order for joining our mailing list.


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This is not the iPhone 5. It's claimed to be an iPhone 5 clone made by a factory in Shenzhen, China, right where the actual iPhone 5 is being produced. Could this really be what the iPhone 5 looks like?
Check out the pictures, because something tells me it could be very close to the real thing.
It certainly matches the plastic cases and the rumors about Apple using rounded glass for the screen and the back. It also matches the alleged spy shot published last week.
From above, it reminds me a bit of the first iPhone. Overall, it feels like a polished merge between the first generation iPhone and the iPhone 4, with the iPhone 3G's smoothed curves factored in as well. Its simplicity is very Apple, and to me it feels like it could be a real Apple design.
The alleged clone is only 7mm thick. That's only 0.275 inches! Obviously, it doesn't have the same guts as the real thing will have, but I certainly expect a thinner iPhone 5.
Why this could be it
In China, many products are often cloned before they even reach the market—based either on digital blueprints or models sneaked out by workers when the products are already in production. That's the reason you see cases and cloned replacement parts of the iPhone or iPad models before they even get released.
Given that the iPhone 5 is probably being churned out of the factories as we speak—either in limited production runs or ramping up—I wouldn't be surprised if someone got a prototype and sold it to some enterprising pirate company.
In any case, it seems way too polished not to be a clone of the actual iPhone 5. I certainly wouldn't be surprised if the real thing looks exactly like this. [Giz-China]
p.s. In fact, I'm so sure that I just made this bet.


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La Sagrada Família
A dream of spires and ornate facades rising hundreds of feet above downtown Barcelona, Antoni Gaudí's fanciful Sagrada Família draws some three million visitors a year. Under construction since 1882, it's now nearing completion.
Works of Antoni Gaudí
Site: Works of Antoni Gaudí
Location: Barcelona, Spain
Year Designated: 1984
Category: Cultural
Criteria: (i)(ii)(iv)
Reason: The Catalan Modernism so important to the cultural identity of Barcelona finds perhaps its greatest expression in the works of one man.
* * *
Seven distinct properties built in and around Barcelona offer many different delights but represent the singular vision of one man—architect Antoni Gaudí.
Gaudí's creative genius—and the curves, shapes, and ornamentations it produced—literally changed the face of architecture and building technology during the late 19th and early 20th centuries. Gaudí recognized the formal order inherent in most architecture before his time—and deliberately turned it upside down. As a result his buildings seem strikingly unique and almost surreal even after a century.
Gaudí's efforts included not only building design but also decorative style and overall settings; his touch was applied to everything from sculpture to gardens. As UNESCO noted in its criteria for listing the sites: "Gaudí's work exhibits an important interchange of values closely associated with the cultural and artistic currents of his time, as represented in Catalonian Modernism (a contemporary movement akin to Art Nouveau). It anticipated and influenced many of the forms and techniques that were relevant to the development of modern construction in the 20th century."
The Casa Batlló is a renovation, not an original construction, yet one accomplished with such style and skill that it has become one of Gaudí's best known projects. Notable here is how the shapely, strange building was washed in color with an extensive facade of ceramics and mosaics.
The Parc Güell is not a building but a green oasis in the midst of the city. Yet Gaudí's distinctive style is seen throughout, from the benches to the porticoes, and lends the entire space an almost magical air.
The Casa Milà, also known as La Pedrera (The Quarry), is awash with balconies both on the exterior and surrounding the interior atrium. All have sensual curved lines, echoed throughout the building, that seem to mimic living structures—a theme seen in many Gaudí works.
Gaudí also left his mark on perhaps Barcelona's most famous landmark: La Sagrada Familia Cathedral.
Gaudí wasn't the building's original architect—he took over from Francisco de Paula after his death in 1883. Nor was he its last; work on the building continues to this day. Nonetheless, Gaudí's distinctive style can be seen in his completion of the chapel of San José, the crypt, and the door of El Nacimiento.
Visitors to the cathedral and other UNESCO-recognized Gaudí properties, whether they know the architect or not, instantly recognize a unique style that has come to characterize Modernist Barcelona and symbolize the city to the present day.
- Nat Geo Expeditions
How to Get There
Barcelona is a major urban center and the full gamut of public and private transportation options are available for visitors.
When to Visit
Barcelona retains its considerable charms 12 months a year. As in many European cities, August can be hot and crowded. Late spring (April to May) and fall (October and November) tend to be the rainier months.
How to Visit
It's certainly possible to explore the works of Gaudí independently and in fact some—like La Sagrada Familia—will be seen by almost all visitors to Barcelona. But aficionados should consider one of the many Gaudí tours on offer. Many guides are full of fascinating Gaudí knowledge and may even be able to gain access to private areas.


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This Math Skills workbook is designed to strengthen a young learner's ability to understand numbers in a variety of ways. Featuring perforated pages, full-color illustration, clear examples, and lots of practice problems, this book will help your first-grader develop the skills that he or she needs to become a confident problem-solver.
Enjoy reading Math Skills: Grade 1? You may also like these books


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Freedom and the Seed is now joining Tempe Birth Center!!
Together we are creating a holistic practice comprising of midwives and students that serve ALL peoples regardless of their race, ethnicity, culture, class, gender, and gender identity, sexual orientation, religion, nationality, or citizenship. We are a team of health professionals dedicated to providing you and your growing family with loving care. We trust that you will find a place among us, and encourage you to make an appointment with us to start the conversation!
We have a beautiful little office nestled in the heart of downtown Tempe at the 1920's historic house called MAMs (Mill Ave Midwives Community Co-Op).
We hope you spend some time on this site exploring who we are and what we do. Check out our resources page for more information about what is happening around the Valley as well as nationally and globally!
contact us
Please feel free to contact us through our new website – www.tempebirthcenter.com or by phone- 480.647.2099- or email- email@example.com – to ask any questions or set up an appointment to meet the team. We are excited to meet you and your growing family!
what will my care be like?
If you have never had holistic care by a midwife, you may be interested to read a description of what it would be like at Tempe Birth Center and Freedom and the Seed. You might find it quite a contrast to typical obstetrical care. Click here to read more information about our care.


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Table of contents | Tables and figures | How to obtain this publication | Related documents
9789264172470 (E-book)
Pages: 123
PISA - Untapped Skills: Realising the Potential of Immigrant Students
A country's success in integrating immigrants' children is a key benchmark of the efficacy of social policy in general and education policy in particular. The variance in performance gaps between immigrant and non-immigrant students across countries, even after adjusting for socio-economic background, suggests that policy has an important role to play in eliminating such gaps. Yet education policy alone is unlikely to fully address these challenges.
How to obtain this publication
Related Documents


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This is a partially developed activity description. It is included in the collection because it contains ideas useful for teaching even though it is incomplete.
Regional water cycle exploration with GiovanniJim Washburne
Topic: Water cycle
Course Type: intro
Explore the transition of rainfall across the US - in particular how significant the 100th Meridian break is between the east and west. Use the Giovani interface and TRMM data sets to plot the East to West latitude averaged rainfall for different annual periods.
Understand how rainfall varies spatially across the western US
Evaluate maps created by Giavoni


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NVIDIA's GF100: Architected for Gamingby Ryan Smith on January 17, 2010 2:00 AM EST
- Posted in
- GPUs
At this year's Consumer Electronics Show, NVIDIA had several things going on. In a public press conference they announced 3D Vision Surround and Tegra 2, while on the showfloor they had products o'plenty, including a GF100 setup showcasing 3D Vision Surround.
But if you're here, then what you're most interested in is what wasn't talked about in public, and that was GF100. With the Fermi-based GF100 GPU finally in full production, NVIDIA was ready to talk to the press about the rest of GF100, and at the tail-end of CES we got our first look at GF100's gaming abilities, along with a hands-on look at some unknown GF100 products in action. The message NVIDIA was trying to send: GF100 is going to be here soon, and it's going to be fast.
Fermi/GF100 as announced in September of 2009
Before we get too far ahead of ourselves though, let's talk about what we know and what we don't know.
During CES, NVIDIA held deep dive sessions for the hardware press. At these deep dives, NVIDIA focused on 3 things: Discussing GF100's architecture as is relevant for a gaming/consumer GPU, discussing their developer relations program (including the infamous Batman: Arkham Asylum anti-aliasing situation), and finally demonstrating GF100 in action on some games and some productivity applications.
Many of you have likely already seen the demos, as videos of what we saw have already been on YouTube for a few days now. What you haven't seen and what we'll be focusing on today, is what we've learned about GF100 as a gaming GPU. We now know everything about what makes GF100 tick, and we're going to share it all with you.
With that said, while NVIDIA is showing off GF100, they aren't showing off the final products. As such we can talk about the GPU, but we don't know anything about the final cards. All of that will be announced at a later time – and no, we don't know that either. In short, here's what we still don't know and will not be able to cover today:
- Die size
- What cards will be made from the GF100
- Clock speeds
- Power usage (we only know that it's more than GT200)
- Pricing
- Performance
At this point the final products and pricing are going to heavily depend on what the final GF100 chips are like. The clockspeeds NVIDIA can get away with will determine power usage and performance, and by extension of that, pricing. Make no mistake though, NVIDIA is clearly aiming to be faster than AMD's Radeon HD 5870, so form your expectations accordingly.
For performance in particular, we have seen one benchmark: Far Cry 2, running the Ranch Small demo, with NVIDIA running it on both their unnamed GF100 card and a GTX285. The GF100 card was faster (84fps vs. 50fps), but as Ranch Small is a semi-randomized benchmark (certain objects are in some runs and not others) and we've seen Far Cry 2 to be CPU-limited in other situations, we don't put much faith in this specific benchmark. When it comes to performance, we're content to wait until we can test GF100 cards ourselves.
With that out of the way, let's get started on GF100.
115 Comments
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x86 64 - Sunday, January 31, 2010 - linkIf we don't know these basic things then we don't know much.
1. Die size
2. What cards will be made from the GF100
3. Clock speeds
4. Power usage (we only know that it's more than GT200)
5. Pricing
6. Performance
Seems a pretty comprehensive list of important info to me.
nyran125 - Saturday, January 30, 2010 - linkYou guys that buy a brand new graphics card every single year are crazy . im still running an 8800 GTS 512mb with no issues in any games whatso ever DX10, was a waste of money and everyones time. Im going to upgrade to the highest end of the GF100;s but thats from a 8800 GTS512mb so the upgrade is significant. Bit form a heigh end ati card to GF 100 ?!?!?!? what was the friggin point in even getting a 200 series card.!?!?!!?1/. Games are only just catching up to the 9000 series now.
Olen Ahkcre - Friday, January 22, 2010 - linkI'll wait till they (TSMC) start using 28nm (from planned 40nm) fabrication process on Fermi... drop in size, power consumption and price and rise is clock speed will probably make it worth the wait.
It'll be a nice addition to the GTX 295 I currently have. (Yeah, going SLI and PhysX).
Zingam - Wednesday, January 20, 2010 - linkBig deal... Until the next generation of Consoles - no games would take any advantage of these new techs. So? Why bother?
zblackrider - Wednesday, January 20, 2010 - linkWhy am I flooded with memories of the 20th Anniversary Macintosh?
Zool - Wednesday, January 20, 2010 - linkTesselation is quite resource hog on shaders. If u increase polygons by tenfold (quite easy even with basic levels of tesselation factor) the dissplacement map shaders needs to calculate tenfold more normals which ends in the much more detailed dissplacement of course. The main advatage of tesselation is that it dont need space in video memmory and also read(write ?) bandwith is on chip but it actualy acts as you would increase the polygons in game. Lightning, shadows and other geometry based efects should act as on high polygon models too i think (at least in uniengine heaven u have shadows after tesselation where before u didnt had a single shadow).
Only the last stage of tesselator the domain shader produces actual vertices. The real question would be how much does this single(?) domain shader in radeons keep up with the 16 polymorph engines(each with its own tesselation engines) in gt300.
Thats 1(?) domain shader for 32 stream procesors in gt300(and much closer) against 1(?) for 320 5D units in radeon.
If u have too much shader programs that need the new vertices cordinations the radeon could end up being realy botlenecked.
Just my toughs.
Zool - Wednesday, January 20, 2010 - linkOf course ati-s tesselation engine and nvidias tesselation engine can be completly different fixed units. Ati-s tesselation engine is surely more robust than a single tesselation engine in nvidias 16 polymorph engines as its designed for the entire shaders.
nubie - Tuesday, January 19, 2010 - linkThey have been sitting on the technology since before the release of SLi.
In fact SLi didn't have even 2-monitor support until recently, when it should have had 4-monitor support all along.
nVidia clearly didn't want to expend the resources on making the software for it until it was forced, as it now is by AMD heavily advertising their version.
If you look at some of their professional offerings with 4-monitor output it is clear that they have the technology, I am just glad they have acknowledged that it is a desire-able feature.
I certainly hope the mainstream cards get 3-monitor output, it will be nice to drive 3 displays. 3 Projectors is an excellent application, not only for high-def movies filmed in wider than 16:9 formats, but games as well. With projectors you don't get the monitor bezel in the way.
Enthusiast multi-monitor gaming goes back to the Quake II days, glad to see that the mainstream has finally caught up (I am sure the geeks have been pushing for it from inside the companies.)
wwwcd - Tuesday, January 19, 2010 - linkMaybe I'll live to see if Nvidia still wins AMD / Ati, a proposal which is as leadership price / performance, or even as productivity, regardless of price!:)
AnnonymousCoward - Tuesday, January 19, 2010 - linkThey should make a GT10000, in which the entire 300mm wafer is 1 die. 300B transistors. Unfortunately you have to mount the final thing to the outside of your case, and it runs off a 240V line.