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Buy Amino Acids Online in Cape Verde
Related Product Varieties
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Are you serious about your fitness goal? Then you require optimum nutritional care such as protein synthesis for cell growth, repairing cells, and many more using amino acid supplements. Ubuy houses some of the best organic amino acid supplements to simplify nutritional fulfillment such as Triquetra Health Plant Aminos Organic Essential Amino Acids, Double Wood Supplements Essential Amino Acids, CLEAN MACHINE Clean BCAA, etc. Chasing your dreams in fitness with us becomes simple with the right amino acid liquid supplements to get the proper muscle recovery. These healthy amino acid supplements are the building blocks of protein for your muscle fiber to grow and rebuild new muscle. With the right choice of essential amino acid supplements, your requirement for the nine vital amino acids gets fulfilled for strengthening bones and joints.
Gluten-Free Amino Acid Supplements are dietary supplements that help out people in reaching their fitness and weight goals. There are different brands that provide gluten-free protein powders to achieve your fitness goals such as Orgain Organic, Vega, Garden of Life, Klean ATHLETE, etc. Some of the most efficient gluten-free amino acid supplements are given below:
This product is a vegan BCAA powder that comes with 3-5x more serving per container. The quality of the product is of the highest pharmaceutical grade, along with the fastest dissolving property. The unique formulation of this product is fine to be used for post-workout recovery while providing 2.5 g L-leucine, 1.25g L-valine amino acid and 1.25g L-isoleucine for effectiveness.
It is a highly functional amino acid recovery supplement that helps you out in maintaining and building up muscle strength and endurance while supporting physical performance and brain function. This amino acid supplement is good for brain function as it offers a proper synthesis of different neurotransmitters and neuromodulators while maintaining healthy immune system function for better health and vitality.
This is an impressive amino acid energy powder that is tested to be effective for every level of athletics. It is the best pharmaceutical-grade amino acid supplement for muscle growth and is efficient in muscle protein synthesis. It can be used as fuel during exercise to help you out in preserving existing muscle tissue.
Ubuy brings you an impressive collection of top branded Amino acid supplements such as KAGED MUSCLE Fermented BCAA Powder, Optimum Nutrition Instantized BCAA Capsules and many more to choose from. Amino acid or protein has great significance in maintaining good health and well-being. Some other effective product choices are given in the following:
This is an effective amino acid liquid supplement that has water-based protein hydrolyzate concentrate along with added free amino acids and vitamin B6. It is also enriched with L-leucine, taurine and vitamin B6 which makes it an effective amino acid supplement for hair growth and skin.
It is an efficient vegan BCAAs supplement that contains natural and clean vegan branched chain amino acids. This amino acid fat-burning supplement is gentle on the stomach and easily gets absorbed without artificial colors, flavors or sweeteners. Just mix one scoop of this amino acid supplement for weight loss in 12-16 oz of water to promote muscle synthesis. The lack of artificial colors, flavors or sweeteners is quite impressive in helping you to stay strong on your weight loss plan.
It is a well performing amino acid supplement for the skin. This product is beneficial for both women and men to support impressive immune function and nitrogen transport. This amino acid supplement for skin growth is manufactured to be Kosher, Vegan and Non-GMO in nature, so you don't have to worry about allergies.
It's a quite functioning BCAA supplement that works well in supporting fitness and allows sports enthusiasts to promote enhanced muscle strength with recovery. These amino acid supplement tablets have the ideal 3000 mg leucine isoleucine valine ratio. It's caffeine free and offers energy and endurance while providing a better focus on stamina to maximize your exercise and with even fast recovery.
The amino acids are considered the building blocks of life and play a crucial role in carrying forward different processes inside the body that includes bodily tissue maintenance, production of some hormones and muscle growth. Some highlighted benefits of amino acids are given in the following:
The amino acid histidine is quite essential for producing histamine which is a neurotransmitter that the body uses to maintain your sleep and wake cycle, promote healthy sexual function and aid in digestion.
An amino acid-like threonine plays a key role in skin and connective tissue production.
The amino acid leucine helps out in regulating the production of growth hormones.
The essential amino acid like phenylalanine is quite impressive in regulating the vital precursor like dopamine, tyrosine, norepinephrine and epinephrine that takes care of your mood, cognitive function and behavior.


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Steve Ballmer just made the single most important decision of his career: In a reorganization that far eclipses his 2005 shake-up, the Microsoft CEO made good on his promise to start turning Microsoft into a "devices and services" company.
There's one little problem: Right now, Microsoft is a software, cloud server, and game company with a toehold in the highly competitive cloud and hardware businesses. It's saddled with a whole lotta losers that are either dying organically or need to be euthanized. Although the change Ballmer announced today may not be as drastic as former CEO Bill Gates's sudden conversion to the Internet faithful, per the famous Internet tidal wave email of 1995, or the introduction of Microsoft software as a service pursuant to Gates's "services wave" email 10 years later, it's going to shake the foundation of every Microsoft product.
The new organization
To make the transition from the cash cow past to the cloudy future, Ballmer has set up two main divisions:
- Cloud and Enterprise Engineering, led by Satya Nadella, the current fair-haired boy deemed by many as most likely to succeed Ballmer, will include "back-end technologies like data center, database and our specific technologies for enterprise IT scenarios and development tools ... data center development, construction and operation."
- Devices and Studio Engineering, led by Julie Larson-Green, a well-respected software engineer who's long been known as ex-Windows chief Steve Sinofsky's able assistant, gets "all hardware development and supply chain from the smallest to the largest devices we build ... studios experiences including all games, music, video, and other entertainment."
Although Nadella has a long, illustrious history leading Microsoft's Server and Tools efforts, Larson-Green's only hardware experience involves the Surface tablet -- damning with faint praise, that. To longtime Microsoft watchers, she's best known as the driving force (with Jensen Harris) for the Office 2007 ribbon interface and Windows 8 Metro interface -- sorry, but to many, damned again.
CFO Amy Hood, HR head Lisa Brummel, and legal boss Brad Smith all keep their current positions.
That leaves a whole lot of "other" at Microsoft -- very profitable pieces of the mothership that are neither devices nor services, including everything from Windows to Office to Dynamics. Those chips fall thusly:
- Qi Lu keeps Bing and "broad applications and services core technologies in productivity, communication, search, and other information categories" in what is now the Applications and Services Engineering group. I can find no official confirmation, but it sounds like the entire Office division has moved under Lu. Office isn't even mentioned in Ballmer's announcement, except for historical references. It's worth remembering: Nadella used to work for Lu.
- In a "small fish swallows big fish" manuever, Terry Myerson gets Windows in the Operating Systems Engineering group. Myerson, you may recall, took over Windows Phone when Ballmer effectively moved Andy Lees out of Sinofsky's acquisition path in December 2011 -- Lees was in charge of Windows Phone, Sinofsky wanted Windows Phone, Lees was moved to the side on "special projects," and Myerson took over Windows Phone. Less than two years later, the guy who was brought in to take care of Windows Phone now finds himself in charge of all of Windows. Sinofsky must be steaming. (More likely, with $14 million in stock coming his way, he doesn't really care.) Responsibilities "span all our OS work for console, to mobile device, to PC, to back-end systems ... [and] core cloud services for the operating system."

subset: commoncrawl


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How many megapixels Camera is in Karbonn K595?
Karbonn K595 Front camera has 0.3 MP megapixels and the Rear camera has 0.3 MP megapixels.
This is a relative score calculated on the basis of the following specifications:
Each Mobiles has been benchmarked against ~31,000 other phones to calculate the score.
For personalized scores based on your preference, you can visit Mobile Recommender to check scores of the recommended Mobiles for you.


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Single-domain antibodies found in camelids are giving researchers a new avenue to create novel treatments for clostridium difficile.
Clostridium difficile
is a health problem that affects hundreds of thousands of patients and costs $10 billion to $20 billion every year in North America. Researchers from the University of Calgary and the National Research Council of Canada say they are gaining a deeper understanding of this disease and are closer to developing a novel treatment using antibodies from llamas.
C. difficile
"We have found that relatively simple antibodies can interfere with the disease-causing toxins from ," says paper co-author Dr. Kenneth Ng, an associate professor of biological sciences at the University of Calgary and principal investigator of the Alberta Ingenuity Centre for Carbohydrate Science. "This discovery moves us a step closer to understanding how to neutralize the toxins and to create novel treatments for the disease."
His research is part of a paper published today in the print issue of The Journal of Biological Chemistry.
C. difficil
Approximately two percent of all patients admitted to hospital may be infected by e, which thrives when healthy bacteria in the gut are weakened by antibiotics, thus allowing spores from m to germinate and colonize the large intestine.
C. difficile
C. difficile
"This research is significant because is an increasing heath care problem and many people may experience multiple infections," says Dr. Glen Armstrong, head of the Department of Microbiology, Immunology, and Infectious Diseases in the Faculty of Medicine at the University of Calgary. "The current treatments are becoming less effective and is developing resistance to conventional antibiotics. This research promises to provide a much-needed alternate treatment option that will overcome the failings of conventional antibiotics."
C. difficile
C. difficile
produces two toxins—toxin A (TcdA) and toxin B (TcdB)—which cause damage to intestinal cells by binding to carbohydrates on the cell surface and disrupting cell functions such as adhesion. The new research shows that what's known as single-domain antibodies bind to the toxins with high affinity and interfere with the toxins' ability to damage cells.
C. difficile
"Llamas have normal antibodies like our own, but they have also developed a second type of antibody with a simpler structure. It is this simpler structure that allows us to make modifications and perform many detailed studies that are not easily done with other types of antibodies," says Ng. "The unique characteristics of these single-domain antibodies provide an attractive approach for developing new treatments for ."
These single-domain antibodies were discovered in 1993 in camelids, which include llamas and camels. Camelids produce conventional antibodies found in all mammals as well as heavy-chain antibodies from which single-domain antibodies are derived. These single-chain antibodies are 10 times smaller than those found in humans and can be more readily engineered into a drug.
Dr. Jamshid Tanha, the corresponding author of the study from the National Research Council in Ottawa says that understanding how camelid antibodies work will ultimately allow researchers to develop a new treatment for this important disease and potentially others.
"We are currently working with Dr. Ng's group to determine why these antibodies are successful," says Tanha.
Currently, licensing opportunities with biotechnology firms are being explored.
Source: University of Calgary


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Most Popular in the Last...
Antibiotic Effective Against Drug-Resistant Bacteria in Pediatric Skin Infections
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial scourge. As its name suggests, MRSA is resistant to most common antibiotics and thus difficult to treat, particularly in children where it commonly causes complicated skin and skin structure infections.
In a randomized, controlled clinical trial -- the first of its kind -- a multi-institution research team reports that daptomycin, part of a new class of antibiotics currently approved only for use in adults, is effective and well-tolerated in children. The findings are published in the March 2017 issue of Pediatrics.
"The safety and efficacy of intravenous daptomycin was comparable to standard-of-care IV antibiotics used for hospitalized children, usually vancomycin or clindamycin for MRSA and cefazolin for methicillin-susceptible strains of S. aureus," said first author John Bradley, MD, professor of clinical pediatrics, co-chief of the Division of Infectious Diseases at UC San Diego School of Medicine and director of the Division of Infectious Diseases at Rady Children's Hospital-San Diego.
"Daptomycin should provide a safe and effective alternative to vancomycin, clindamycin or linezolid for IV treatment of invasive MRSA skin infections. Concerns for vancomycin renal toxicity and clindamycin antibiotic resistance were not present. There was no evidence of daptomycin toxicity in the trial."
The Food and Drug Administration is currently reviewing whether to approve daptomycin use in children.
MRSA infections are commonly associated with patients in hospitals and nursing homes whose immune systems are weakened, but community-associated MRSA (CA-MRSA) is widespread, readily transmitted at daycare centers, playgrounds and in schools where children have frequent skin-to-skin contact, share toys that have not been cleaned and are more likely to have scrapes, abrasions and bites that offer potential infection entry points.
CA-MRSA usually causes skin infections but can lead to more serious consequences, such as pneumonia and infections of bones and joints. Daptomycin is active against MRSA and was approved for use in adults in 2003 for treatment of skin and skin structure infections, and for bloodstream infections three years later.
The new study was a prospective, randomized, investigator-blinded study that included more than 250 daptomycin-exposed children, ages 1 to 17, to document safety and efficacy of the antibiotic in treating pediatric skin and skin structure infections. Dosing was based on adult experience, but researchers found that the younger the child, the more quickly their bodies eliminated daptomycin. Thus pediatric doses increased as the age of the research participants decreased.
"Most news these days is about the declining utility of antibiotics as microbial resistance becomes more widespread and intractable," said Bradley. "These findings are encouraging. Daptomycin appears to be a suitable, once-a-day alternative to existing antibiotics with harsher side effects."
Co-authors include: Chad Glasser, Hernando Patino, Minjung Yoon, Diane Anastasiou, Dominik Wolf, and Paula Bokesch, Merck; Sandra L.R. Arnold, University of Tennessee; Antonio Arrieta, Children's Hospital of Orange County; Blaise Congeni, Akron Children's Hospital, Ohio; Robert Daum, University of Chicago MRSA Research Center; and Tsoline Kojaoghlanian, Children's Hospital at Montefiore, Bronx, NY.
Disclosure: Bradley, Arnold, Arrieta, Congeni, Daum and Kojaoghlanian were study site principal investigators whose respective employers received institutional research funding from the study sponsor, Merck. Additionally, UC San Diego received funding from Cubist Pharmaceuticals, now part of Merck, to advise Cubist on clinical trial design.
Scott LaFee
[email protected]
- Tags:
- bloodstream infections
- cefazolin
- clindamycin
- clindamycin antibiotic resistance
- community-associated MRSA (CA-MRSA)
- Division of Infectious Diseases at Rady Children's Hospital-San Diego
- Division of Infectious Diseases at UC San Diego School of Medicine
- efficacy
- intravenous daptomycin
- John Bradley
- methicillin-resistant Staphylococcus aureus (MRSA)
- pediatric skin and skin structure infections
- safety
- standard-of-care IV antibiotics
- U.S. Food and Drug Administration (FDA)
- University of California
- vancomycin
- vancomycin renal toxicity
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"I was frozen:" Bill Cosby accuser says she was drugged, groped
NORRISTOWN, Pa. — Bill Cosby's chief accuser took the stand at his sexual assault trial Tuesday to tell her story publicly for the first time, saying the comedian groped her after giving her three blue pills that left her paralyzed and helpless.
"In my head, I was trying to get my hands to move or my legs to move, but I was frozen," Andrea Constand, a 44-year-old former employee of the basketball program at Temple University, Cosby's alma mater, said in their long-awaited courtroom confrontation. "I wasn't able to fight in any way."
She added: "I wanted it to stop."
Cosby, 79, is charged with drugging and violating Constand at his suburban Philadelphia home in 2004. The TV star once dubbed America's Dad could get 10 years in prison if convicted.
Constand, an athletic 6-footer with dark curly hair, could face a bruising cross-examination from Cosby's lawyers, who have argued that the two had a romantic relationship, that she wasn't incapacitated and that the sexual encounter was consensual.
Constand was calm and collected as she testified, looking at the jury as she began describing the assault.
She said Cosby gave her pills he claimed were a natural remedy to ease her stress about a looming career change. "They're your friends. They'll take the edge off," she quoted him as saying.
She told the jury she started feeling woozy after about 20 minutes, with blurred vision, slurred words and legs that felt like rubber. Cosby then penetrated her with his hand and also placed her hand on his penis and moved it back and forth, she said.
She said she was unable to push him away or tell him to stop.
Afterward, Constand said, "I felt really humiliated and I felt really confused."
Cosby, sitting across the room at the defense table, leaned in to listen, whispered to his lawyer and, at times, shook his head.
Before Tuesday, Constand had never spoken about Cosby in public, barred from doing so under the terms of a confidential settlement they reached in 2006. Her deposition from that lawsuit remains sealed.
Some 60 women have come forward to say Cosby sexually violated them, all but destroying his nice-guy image, but the statute of limitations for prosecution had run out in nearly every case. Constand's case is the only one in which Cosby has been charged.
Constand, who is from the Toronto area, met Cosby while working for the women's basketball team at Temple, and she said they became friends over conversations about the team and later her career. He invited her to dine with him at his home.
Cosby was "somebody I trusted," Constand said. "A mentor."
But he had also previously made advances on her, she said. One time, he placed a hand on her thigh. Another time, she said, Cosby tried to undo her pants but took his hand away when she leaned forward and told him: "I'm not here for that. I don't want that."
Asked by a prosecutor why she remained friends with him, she said: "I wasn't scared of someone making an advance at me or a pass at me."
The defense has pointed out that phone records show Constand called Cosby 53 times after she says he assaulted her. Constand told the jury the calls mostly involved the women's basketball team, especially around tournament time.
"It had more to do with business than it did with me personally," she said.
Constand also said she went to a performance of Cosby's later that year with her family in Canada after Cosby arranged to drop off tickets. She felt "terrible" about it, she said, especially when her mother brought Cosby some Canadian souvenirs.
"It was a very big burden on me, but ... I did not have the courage at the time to tell my family," she said. "So I just went along with them."
The stage was set for Constand's testimony after prosecutors used the first day and a half of the trial to argue that Cosby made a habit of knocking women out with pills and then molesting them.
Kelly Johnson testified on Day 1 that Cosby drugged and molested her at a Los Angeles hotel bungalow in 1996. She said she lost consciousness soon after Cosby pressured her to take a large white pill. She said that when she awoke, her breast was exposed, and a naked Cosby forced her to sexually gratify him with her hand.
On Tuesday, Johnson's mother, Pattrice Sewell, bolstered her daughter's story. She told jurors that Johnson was distraught during a telephone call in 1996, fearing Cosby was trying to get her fired from her job working for the comedian's agent.
A few weeks later, Sewell said, Johnson disclosed that she had woken up next to Cosby in bed with her clothes askew.
Sewell said they didn't go to police at the time because her husband, a Los Angeles detective, feared the ordeal that would ensue.
"Her father didn't want her to be humiliated and feel shame and embarrassment as he had seen other women go through when they went to the police at that time. He didn't want that," Sewell said.
Johnson told a similar story about Cosby in 1996, when she gave sworn testimony as part of a workers' compensation claim, lawyer Joseph Miller testified Tuesday.
She claimed to have developed debilitating stress from her secretarial job at the William Morris Agency and eventually settled for around $10,000, according to Miller, who represented the talent agency in the case.
But Miller's account differed from Johnson's in at least one respect: Under questioning from Cosby's lawyers, Miller said his notes show Johnson told him the encounter with Cosby happened in 1990, not 1996.
The Associated Press does not typically identify people who say they are sexual assault victims unless they grant permission, which Constand and Johnson have done.


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Associated Press –
October 16, 2012:
Sacramento — California lawmakers will begin hearings this week into how the state will end a health program serving more than 860,000 children without disrupting care.
The state budget enacted this year eliminates Healthy Families to save $73 million a year. Its participants will be moved to Medi-Cal, California's version of the Medicaid program for the poor.
Healthy Families benefits low-income families who did not qualify for Medi-Cal.
A top concerns is whether health care providers will be willing to accept the new patients because they were reimbursed at a higher rate under Healthy Families. They could receive 15 percent less under Medi-Cal.
California Health and Human Services Secretary Diana Dooley says she believes enough health providers will be willing to care for the children at the reduced rates.


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Freeglut is intended to be a 100% compatible, completely opensourced clone of the GLUT library. GLUT is a window system independent toolkit for writing OpenGL programs, implementing a simple windowing API, which makes learning about and exploring OpenGL programming very easy.
This package is known to build and work properly using an LFS-7.6 platform.
Download (HTTP): http://downloads.sourceforge.net/freeglut/freeglut-2.8.1.tar.gz
Download MD5 sum: 918ffbddcffbac83c218bc52355b6d5a
Download size: 984 KB
Estimated disk space required: 11 MB
Estimated build time: 0.1 SBU
User Notes: http://wiki.linuxfromscratch.org/blfs/wiki/freeglut
Install Freeglut by running the following commands:
./configure --prefix=/usr --disable-static && make
This package does not come with a test suite.
Now, as the
root user:
make install
--disable-static: This
switch prevents installation of static versions of the libraries.
Last updated on 2014-09-16 10:29:57 -0700


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A new survey based on "evolutionary algorithms" identified the best possible VP ticket for both Barack Obama and Mitt Romney by trying out 100 million combinations of vice presidents, platforms, slogans and candidate images. The result: Each would've performed better with swing voters if they had chosen strong female candidates — Condoleezza Rice for Romney and Hillary Clinton for Obama, to be specific — as running mates.
Remember when it looked like Romney was going to go with a lady like Kelly Ayotte for his VP pick? What happened? Experts say he decided it would be to risky to pick a woman as his running mate because of all of the unavoidable Sarah Palin references.
"Whoever Romney picks, if she's a woman, would have to first demonstrate how much better than Sarah Palin she actually is, and that's not necessarily a good use of the campaign's time," Jennifer Lawless, the director of American University's Women and Politics Institute, said in July. "Mitt Romney is ultimately going to find himself between a rock and a hard place because although it is important to demonstrate that there are qualified women who should be on the short list, the onus is then going to be on him to explain why they weren't his ultimate pick and he's not going to say, 'because I don't want voters to think of Sarah Palin. So he's going to have to navigate a pretty fine line and ensure that if he says that the most qualified person turns out to be a man that indeed that person is more qualified than some of the women's names who are floating around."
Would the aftermath of Legitimate RapeGate be any different if Romney had a woman by his side?


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solo exhibition
The world of fish-larvae and invertebrates larvae living in the ocean. Ryo captured clear figure in the sea of night by shooting like prominent craftsmanship and revealed unknown ecology one after another. Larva's amazing technique and strength that support by function is artistic, and world of powerful life is expanded that beyond our imagination.Read More
Photographs by Ryo MINEMIZU
Photographs by Ryo MINEMIZU


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Edgar Solomonik wins Householder Prize for best dissertation in numerical linear algebra
Alumnus Edgar Solomonik (CS Ph.D. '14, adviser: James Demmel) has won the Alston S. Householder Prize XX (2017) for the best dissertation in numerical linear algebra. The Householder prize, which is presented once every three years at a Symposium held in cooperation with the Society for Industrial and Applied Mathematics (SIAM) and the SIAM Activity Group on Linear Algebra, has two winners this year. Edgar's dissertation, titled "Provably Efficient Algorithms for Numerical Tensor Algebra," also won the EECS Department's David J. Sakrison Memorial Prize for truly outstanding research. Edgar is currently an Assistant Professor in the Department of Computer Science at the University of Illinois at Urbana-Champaign.


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Let's face it : this forum is dedicated to uncover the 'best kept secrets' of this planet, so let's give this most crucial matter of our times some scrutiny. The quoted text below is what Piper, our newly registered member (-welcome!-), expounded in another discussion of this forum. I thought it very much deserved its own thread - so here it is.
PIPER wrote:
I discount the existence of "nuclear" bombs as a fear-mongering "Sword of Damocles"-type illusion that has now successfully kept billions of people living in fear of nuclear annihilation for 65 years. This is based on the improbability behind the science of the explosive device and the alleged mechanism that powered it, as well as the obviously forged videos and the high propaganda value behind the idea, since the firebombing of Hiroshima and Nagasaki served to kick off the fake "cold war" and the fabricated "arms race", which featured both the US and Russia pocketing billions in their taxpayers' money for the manufacturing of these fake "nukes" and, some years later, for the "disarming" of same fake "nukes".
I hope Piper will elaborate on this and further develop this extremely important topic. Meanwhile, here's my little contribution to this subject. Enjoy
A comparison of two 'historical' images meant to depict the Nagasaki nuke :
Of course, one of them must be fake. Or perhaps - uh...- could both be? To those unfamiliar with photo-analyses: Note that the background in the pictures has evidently moved - meaning the 2 shots (if real) must have been snapped at different moments in time(as the airplane moved along). Now, look at the mushroom cloud in the foreground: It is identical in shape. Enough said? Or are you willing to believe that the mushroom cloud's shape remained static between the two shots? Or that the two shots were captured by two photographers - from two different airplanes - at the exact same moment in time?
Good luck with your beliefs.


text: Is it normal for Linux (in my case Fedora RC4 used as only webserver) that the free / used RAM keeps going down, up, down, up ect ect? Have a look at this image: Note that I have added 2GB more of RAM on Saterday. Right now the free RAM is down to about 128MB!


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I think the highly intelligent plant world is trying to tell us something with this chunk of cauliflower.
Doesn't it look like a mid-sagittal section right out of a frontal lobe, complete with cerebral white matter?
Or, maybe networks of giant axons and dendrites. This head (whoa, it's even called a head) of cauliflower appears to be a bit left-brain-heavy. What do you think? More neural pathways on the left side? Aaah, must be a linear thinker.
I'll put aside my vivid imagination and interest in plant autopsies for a moment and talk about the healing power of whole foods. Most of us have enough bizarro stuff going on inside our heads that can sabotage our good intentions, let's at least give our thoughts some powerful building blocks and mighty antioxidants to work with.
Food for thought
I can't start this "brain food" list without commenting on gluten as a neuro-cootie. This is official – research has shown gluten to be a neuro-toxin (for some susceptible people). It can cause ataxia, epilepsy-like symptoms, peripheral neuropathy, depression, migraines, brain fog and a host of other neurological problems. In some rare instances, the neurological impact of gluten can even mimic ALS (Lou Gehrig's Disease), MS and Parkinson's Disease. Get tested for celiac disease if you have unusual neurological symptoms. A gluten-free, whole foods diet may (will) be beneficial. Check here for Dr. Rodney Ford's take on this years ago. Scientific research is finally catching up to his diagnostic skills as a physician.
Nutrition for neurons (the basics)
• EFAs (essential fatty acids) are important for brain function. Wild-caught salmon and other cold-water fish, flax seeds, nuts, and pastured eggs are examples of foods rich in EFAs.
• Proper hydration is important for brain function. Dehydration causes the release of stress hormones, which impact neurons.
• Organic, whole foods rich in antioxidants should be the focus of a "healthy brain" diet. Antioxidants help prevent and repair cell damage.
• Sunshine stimulates the production of vitamin D, which is thought to aid in the protection of neurons. Plus, a little sunshine can boost your mood.
My top 8 food picks for brain health
This list is just a random assortment of nutrient-dense foods that I like and are high in antioxidant power. I've chosen foods that are easy to find and that people might actually eat. No need to scour the Amazon rainforest floor for some exotic plant or climb the Himalayas for a power-packed berry. Seriously, let's make this easy. Organic is always best and I prefer eating the whole food rather than counting on supplements. That way you get a diverse combination of beneficial phytonutrients.
1. Cauliflower (I had no choice, this one looks like a brain)
Cauliflower is packed with vitamin C, a powerful antioxidant. Research is mounting that oxidative damage to brain cells may precede diseases like Alzheimer's and other forms of dementia. One cup of raw cauliflower contains 94% of the daily value for vitamin C. It's also anti-inflammatory and is a good source of protein, calcium, iron, magnesium, zinc and other plant goodies.
2. Wild-caught salmon (as mentioned above)
Please check out this past post I did on EFAs and why they are important for brain health. The post also includes a detailed break-down of omega-3s and omega-6s and a wonderful salmon recipe. Lots of good brain-building information in that post.
3. Blackberries, blueberries, cranberries, raspberries, strawberries, cherries.
All of these fruits are packed with antioxidants. Don't stick with one choice – mix and match them for a variety of protective compounds.
4. Mustard greens
You're probably thinking this is an unlikely choice for the top 8 brain foods, but I've decided it's a good representative for leafy greens in general (kale, collard greens, spinach, chard). One cup of mustard greens, which I've recently become quite fond of, has 118% of the daily value of vitamin A and 65% of the daily value of vitamin C. It's also a good source of vitamin E and it's anti-inflammatory. A, C and E are all antioxidants, so this green is a good one to make friends with. I throw it in smoothies.
5. Coffee
Surprise, surprise! As those of you following this blog know, even though I'm a nutritionist, I don't think coffee is evil. In fact, I like the stuff in small doses and guess what? It's not only high in antioxidants, research indicates the caffeine in coffee has a neuroprotective effect. Choose organic coffee, use in moderation (1-2 cups per day) and don't drink it later in the day.
6. Beans
Beans are a good source of easily-absorbed amino acids, which are important in the production of enzymes and neurotransmitters.
7. Organic, pasture-raised chicken eggs
Eggs are one of the best sources of high-quality protein. Pastured eggs are also high in omega-3s, vitamin A, vitamin E and B vitamins, all of which are important for healthy brain function.
8. Dark chocolate
Good, high-quality dark chocolate in moderation is a good source of antioxidants. Plus, a chunk of dark chocolate now and then puts you in a good mood and makes you a nicer person. I'm nicer when people give me chocolate. Aren't you?
Peace, love and brain power!


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Most businesses have a normal distribution of talent — a limited number, say top 10 percent, of high potential, rock star performers, a bottom decile of underperformers, and a thick middle of 80 percent of folks who get the day-to-day stuff done. In well-managed businesses, there are clear feedback mechanisms to ensure that the bottom of the talent pack gets managed out efficiently and objectively. While at GE, Jack Welch popularized the notion that it was good to fire the "bottom 10" of his managers every year. On the other end of the spectrum, the better companies manage the top-end of their talent pool, providing mentors to groom this group of next-generation of leaders and compensating them differentially in recognition of their superior performance.
The challenge lies in productively managing talent's fat middle. What is the right people strategy for the average employee — the stalwart who is performing well enough, but is not necessarily a standout? Here are a few of the challenges with the middle base of talent:
• Almost by definition, they often get lost in the mix, lacking appropriate guidance and management attention. This creates an issue of not understanding who holds real potential to move up the talent curve with the right nurturing, versus those who have limited upward mobility, versus those who should not be at the company.
• They can be a drag on those who truly are the best. While not everyone can be above average, the more mediocre talent you have in a business, the more likely it is to have a negative effect on those who can really make a difference. This creates retention and motivation issues for your higher performers. There will always be a distribution, even if it is a forced curve, of talent potential and capability in a business. But the goal should be to raise the overall average of the entire pool, and avoid letting it get pulled down.
• In a similar vein, average talent can harm a firm's talent recruitment potential since those who are average tend to be more threatened by bringing in better people. The adage of "A's" attracting "A's" and "B's" attracting "C's" holds true.
So what should business builders do to better manage their talent base — especially in this middle area? Two simple ideas can help:
• First, the best practice of conducting regular and specific performance feedback is critical. It is equally important to make sure that the person doing the review is capable and respected. Senior people who are responsible for managing the middle pool of talent should also be managed on their own ability to see, sift, cultivate, and retain the very best of that pool. How you grow and mentor organizational talent should be an evaluation criterion for senior managers' performance. Mentees and direct reports feel differently when they know their own managers are being evaluated (with real implications for good or bad performance) on their ability to effectively manage, mentor, and cultivate talent.
• Second, at regular intervals of a person's career, there should be not just "performance reviews" but also what I call a "Fit Test Point." Too many times we see someone who can do the job, but if we are truly honest know that in the long-run they will be stuck in the middle of the organization. My sense is that companies spend more time discussing performance than they do "fit." Performance reviews are biased towards looking out for the best interests of a company — as long as someone is doing their job they have a place. A "Fit Test Point" is a tool to carefully consider the best interests of an employee. Is this person in product development really better served finding a position as an industry or market researcher, or is that analyst who can clearly make the next two rungs of the management track better served making a switch in her career now given the opportunity cost of time? We all know situations where instincts and experience alerted us that a job was not the best fit for someone, yet we let the person continue because they filled a short-term need or because we lacked the courage to have the honest "Fit Test" conversation. Consider key inflection points of one's career advancement and have the parallel conversation of performance and fit reviews.
Trying to serve everyone equally does not do anyone a service, but catering only to the top of the talent pool or overemphasizing the middle or bottom also does not work. An explicit strategy for managing each tier of talent needs to be in place. The public education system has shown that if we just settle, accept, and teach to the middle that is a formula for failure. As business leaders we should see how we can realize the full potential of each employee and help those who are not right for the business find other jobs where they can be more productive and happier.


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"You must remember this, a kiss is still a kiss".
Your romance is Casablanca. A classic story of love in trying times,
chock full of both cynicism and hope. You obviously believe in true love,
but you're also constantly aware of practicality and societal expectations.
That's not always fun, but at least it's realistic.
Try not to let the Nazis get you down too much.
What Romance Movie Best Represents Your Love Life?
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text:
In the villages of Guatemala, women take great pride in stitching an array of vivid colors and motifs onto their cotton garments, called huipiles. Our Guatemalan Artisan Partners transform these traditional textiles into gorgeous luggage tags that brighten up every journey.
Wipe down with a dry, soft cloth.
This piece is made by Artisans in Guatemala, most of whom are women. Because of the portability of their projects, the women are able to work almost anywhere, from their homes to the local market. This flexibility allows them to become breadwinners for their families while being able to care for their young children at home.
In Guatemala, young girls grow up watching their mothers and grandmothers create traditional crafts by hand. To make our jewelry, Artisans use glass beads and tiny looms to create intricate designs. For our handcrafted woven fabrics, women use natural dyes whenever possible. They boil local flowers, berries, and bark to create styles that are both beautiful and eco-friendly.


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Job Interview Tips 101
Scout it out
There are several reasons to pay a visit to a company before you have your interview. You will know how to get there and how long it takes. You will see how people in the office dress. You will meet the receptionist and learn his name. This is also a good person to ask about the company in general. You can pick up any literature on the company that may be provided in the reception area: annual report, sales brochures, newsletter. You can find out the name of the person who will interview you, if you haven't been told already.
Be on time
There are no exceptions to this rule. If necessary, perform a trial run to see how long it takes to get to your destination. If an unforeseen emergency arises (the subway breaks down between stations), call as soon as possible: apologize, explain and offer to reschedule. Even that may not save the situation.
Dress appropriately
In the old days, a coat and tie or suit would usually do the trick. Now, offices run the gamut from shorts and sandals to "office casual" to traditional suits. Do your homework. Either call or visit to find out what the office dress code is. A visit will let you see what your future colleagues wear to work. A good bet is to dress slightly more formally than the average. In other words, if most people wear slacks and a sport shirt, wear slacks with a coat and tie. Everyone in coat and tie? Wear a suit. Everyone in a suit? Wear your Best Suit.
Piercings and Neon Hair
Yes, they're all the rage and you love your lip ring and purple streaks. And, yes, you have a perfect right to be who you are. Just remember, corporate America is not into fashion trends. They have just as much right to say that lip rings are not the image they are trying to project at XYZ Widgets. You will have to decide if your personal statement is worth more than the job. Of course, there are plenty of industries—fashion and music to name two—where no one would blink at piercings or creative hair.
Neatness is as important as wearing appropriate attire. Your shoes should be shined and your clothes should be pressed and spotless. No hanging threads, tears or missing buttons. Hair should be freshly combed and nails clean and trimmed. Women should keep make-up simple and hairstyle tidy. Use an extra swipe of antiperspirant, but lay off the cologne.
Six Ways to Make a Good First Impression
- Shake hands when you introduce yourself.
- Sit down only after your interviewer invites you to do so.
- Stand up when anyone is introduced to you.
- Say "Thank you"—at the beginning, at the end and once again in a written note.
- Speak clearly and make eye contact.
- Smile: It shows you are inviting and friendly, confident but not cocky, able to be relaxed and personable in a potentially stressful or intimidating situation.
The Name Game
Nothing is more awkward than having people ask who you are! Introduce yourself to the receptionist and give your name! "Hi, my name is Mary Smith. I have a 10 o'clock interview with Jane Doe." Make a note of the receptionist's name. Be sure to know the name of the person interviewing you. "How do you do, Ms. Doe, I am Mary Smith. Thank you for seeing me today."
"Stand up straight, look 'em in the eye, say their name, and give 'em a firm handshake," was Peter Post's dad's recipe for making a good impression. If you are in doubt about this principle, practice with a friend. Have your friend look off in the distance and offer you a limp hand. Have your friend look at your feet and mumble something. Have your friend squeeze your hand and pump your arm enthusiastically. Now have your friend look you in the eye and give you a firm handshake. What do you think? Now, buy your friend a cup of coffee.
Say thanks
At the end of the interview, stand, thank the interviewer for her time, look her in the eye and shake her hand. A short note of thanks—nothing fawning—is also appropriate.
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Cornwall April 2013
In late May 2013, Maggie took me on a surprise trip for a week to Cornwall to celebrate my 70th birthday. To make it even better, Jayce was able to join us. We stayed in the beautiful coastal town of Mevagissy and did day trips from there. We spent my actual birthday on St Ives which is an amazing place full of art galleries. We also went on a number of coastal walks and as you will see had glorious sunny weather.Read More


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In the 1980s, the Soviet Union built nuclear-powered ice-breakers, hoping to open a shipping route through the Arctic. They needn't have bothered — there's no ice left now in the summer, opening the fabled Northeast Passage to shipping.
According to a new report in Barents Observer, the Northeast Passage, now renamed the Northern Sea Route, will become the new shipping route between Europe and Asia, now that it's proved to be ice-free. The journey through the Arctic Ocean was a hazardous one when Finnish-Swedish explorer Adolf Erik Nordenskioeld made the 15-month journey in 1878-1879. But this summer, Norwegian explorer Børge Ousland sailed the exact same route in his little trimaran. It took a few weeks instead of 15 months, and he hardly saw any ice. In fact, he hardly saw any living things at all. He told a Norwegian broadcaster:
The most surprising with this trip is that we have hardly seen any animals at all. We have only seen animals, seals, walrus and polar bear where there has been ice.
The photos above and below come from 2007, and they show the icebergs in the region melting. But that ice is completely gone in the summertime.
According to the upbeat report in the Barents Observer, 2009 was the first year that shipping companies discovered the region was ice-free, and 2010 was the "breakthrough year." And 2011 will be the year that shipping in the region takes off completely. Says the Observer article:
The Russian and international shipping industry see the ongoing climate changes and the retreating of the summer ice-cap in the Arctic as a new opportunity. The distance from Europe to Asia is much shorter when sailing north instead of using the Suez channel or sail around Africa. Shorter sailing route save time and save fuel. In other words; save money. Also, the Arctic is free of pirates... When the future history of the Arctic will be written, 2010 will be marked off as the breakthrough year for commercial shipping along the Northern Sea Route.
Everybody wins!
Photos by John McConnico/Associated Press. [Barents Observer]


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In the wake of a tornado that leveled Greensburg, Kan., in May 2007, local residents forged an ambitious plan to rebuild the small agricultural town with a focus on sustainability. For a group of Princeton students who traveled there over fall break, this effort became an important lesson both in environmental awareness and civic engagement.
A dozen students spent the first week of November in Greensburg on one of seven Breakout Princeton civic engagement trips, which are designed and led by students and overseen by the Pace Center. The "Green Design in Greensburg, Kansas" trip was intended to teach the students about green design while introducing them to social issues involved in the town's revitalization.
The Princeton contingent met with Greensburg GreenTown, a grassroots organization that works with local officials, business owners and residents to incorporate sustainable principles into the rebuilding process. Community support of the green design mission led to an ordinance requiring work on all municipal buildings larger than 4,000 square feet to adhere to the U.S. Green Building Council's Leadership in Energy and Environmental Design standards. Projects completed or being built under these standards include a new city hall, a small-business center, a hospital and a K-12 school building as well as a renovated county courthouse.
The Princeton students visited green building sites and prepared PowerPoint presentations for Greensburg GreenTown to use in future educational sessions on sustainable design. To learn more about the community, they also worked on a farm and interacted with local officials and residents in various settings, including a high school football game.
"Everybody learned a lot about green design, but one of the highlights was seeing how it was really the community that made it all work in the end," said junior Megan Prier, who led the trip with classmate Liz Parsons. "We saw how they came together after the tornado and how they were all really enthusiastic and willing to learn and help one another."
Parsons said the students came away with more awareness of how "going green is not hard to do. It's about, in many cases, making the little changes that will pay off in the long run." She added that she and the other students, most of whom come from urban communities, were struck by the community spirit they witnessed in the rebuilding of Greensburg.
"What I personally will take back is an appreciation for rural communities like this and the degree to which these people, after coming out of their basements that night and seeing the destruction, actually had the foresight to imagine a town like this," Parsons said. "I think that's really an incredible accomplishment and something that we can look to as a model for other communities in the future."
Student interest in the Breakout Princeton program has grown steadily since it was launched two years ago to facilitate students learning about and taking action on issues of public significance in communities across the country. The Pace Center increased the number of trips from five to seven this semester and received 120 applications for the 70 available spots, according to Andrew Nurkin, senior program coordinator at the Pace Center. Including trip leaders, 83 students participated in the fall program. The Undergraduate Student Government has directed funds to the Pace Center to support the Breakout program this spring, among other civic engagement activities.
In addition to the Greensburg visit, the roster of fall trips included: "Mass Incarceration in New York and New Jersey"; "Deaf Education in Washington, D.C."; "Stigma of Mental Illness in New York City"; "The Rule of Law on the Pine Ridge Reservation in South Dakota"; "Music Outreach in Philadelphia"; and "Closing the College Awareness Gap in Brooklyn."
Participants in the Philadelphia trip discussed music outreach issues with members of the Philadelphia Orchestra, students from the Curtis Institute of Music and representatives of Pieris Music, a performance, education and advocacy organization. They also engaged with preschool students in Settlement Music School, performed outdoor service work at the Village of Arts and Humanities and made phone calls on behalf of WXPN, a public radio station. In addition, they attended concerts and visited cultural venues such as the Painted Bride Arts Center.
"It wasn't always music-themed service that we were doing, but we were doing the service for music organizations," said trip co-leader Eddie Skolnick, a sophomore. "That's where the philosophy of Breakout comes into play -- we learn how other people do it by interacting with their organizations."
Skolnick, who began playing violin at age 5, performs with the University Orchestra and leads the Princeton Music Outreach program through the Student Volunteers Council, which currently focuses primarily on visits to area nursing homes. One of the main goals of the trip was to generate ideas for how to enhance outreach efforts back on campus.
"What I hope to do, now that I have experienced this trip and seen all of these different things in Philadelphia, is try to expand our program to encompass more diverse activities," such as performances in parks, hospitals, schools or other local venues, he said. "I also want to try to incorporate more educational elements, because I think that education is one of the greatest payoffs of music outreach."
Skolnick's co-leader, sophomore Pauline Ndambuki, has no musical background but said she wanted to participate in the trip to see how music could be used in civic engagement.
"Music doesn't seem like the most common tool for people to say they're helping the community with because when I think of music I see it not so much as a good as it is a skill, so that was really enticing to me," Ndambuki said. "Seeing the enthusiasm of the community partners, how much they're willing to put in with underprivileged communities, was really interesting to me."
Her favorite part of the trip was the visit to the preschool, where "they used music as a teaching tool for moral lessons about sharing, being friends and how to communicate with other people. I thought that was really impressive."
For Ndambuki, the Breakout trip reaffirmed her commitment to the importance of service to those who are less fortunate. "It has shown me that it's not just about help that is tangible," she said. "One can give knowledge that can help mollify, encourage and empower people during tough times."


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NBC Radio Broadcast: Toscanini - The Man Behind the Legend, 1/1/1964
Description: This recording is a part of the radio series "Toscanini: The Man Behind the Legend," which was a tribute to conductor Arturo Toscanini. The broadcasts consist of music performed by the NBC Orchestra as well as interviews with composers, conductors, orchestra members, and other people associated with Toscanini. This segment includes performances of Beethoven's Leonore Overture No. 3, Barber's Adagio for Strings, Mozart's Bassoon Concerto No. 1, and interview with Remo Bolognini.
Date: January 1, 1964
Duration: 23 minutes 55 seconds
Creator: Gillis, Don
Partner: UNT Music Library


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QUESTION: In patients with fungal infections of the skin of the foot (tinea pedis), does oral treatment eradicate the infection?
Data sources
Studies were identified by searching Medline (1966–2000), CINAHL (to 2000), SCI and SSCI (1969–2000), EMBASE/Excerpta Medica (1980–2000), the Cochrane Controlled Trials Register, CAB-Health (1973–97), HealthSTAR (1975–97); handsearching podiatry journals; reviewing bibliographies of reviews; and by contacting pharmaceutical companies and podiatry schools.
Study selection
Studies were selected if they were randomised controlled trials evaluating oral treatment in patients with clinically diagnosed and microscopy and laboratory confirmed tinea pedis.
Data extraction
2 reviewers independently extracted data on study design, condition, intervention, patient characteristics, study quality, and outcomes. The main outcome measure was mycological cure (negative results on microscopy and no dermatophyte growth in culture). Secondary outcomes were such clinical signs as redness, scaling, pustules, itching, burning, soreness; recurrence of the condition after achieving cure; and side effects.
Main results
12 trials were included and evaluated 5 antifungal treatments. 2 trials (1 of terbinafine and 1 of itraconazole) were placebo controlled; 9 trials compared different oral drugs (terbinafine, itraconazole, ketoconazole, fluconazole, and griseofulvin); and 1 trial compared different doses of fluconazole. Both active drugs were more effective than placebo: terbinafine, 250 mg/day for 6 weeks, had a 65% (95% CI 45 to 86) absolute benefit increase (ABI) 2 weeks after the end of treatment. Itraconazole, 400 mg/day for 1 week, had an ABI of 47% (CI 29 to 67) 8 weeks after the end of treatment. Among the 9 trials comparing different drugs, terbinafine was no better than itraconazole in 3 trials, but 1 trial showed a benefit in favour of terbinafine (ABI 32%, CI 16 to 47); itraconazole (1 trial) and ketoconazole (1 trial) did not differ from fluconazole; and griseofulvin did not differ from ketoconazole (1 trial). 2 trials comparing griseofulvin, 500 mg/day, with terbinafine, 250 mg/day, for 4 or 6 weeks, showed a higher cure rate with terbinafine (pooled ABI 52%, CI 33 to 71). 1 trial comparing fluconazole, 50 mg/day for 6 weeks, with 150 mg/week for 6 weeks, showed no difference in cure rates. All trials reported short term side effects, including diarrhoea and nausea (most common); headache; and rash, dermatitis, and pruritus.
In patients with fungal infections of the skin of the foot, terbinafine or itraconazole eradicate infection better than placebo, and terbinafine is better than griseofulvin. Different azoles and different doses of fluconazole do not differ in effectiveness.
Currently, the selection of treatment for tinea pedis is muddied by the availability of both topical and systemic antifungal drugs. In this systematic review of oral treatments for tinea pedis, Bell-Syer et al note that topical treatment may be the realistic first line treatment plan.
Topical allylamines have been shown to produce a faster response than azoles, but the cure rates are similar.1 If the cost and availability of the products are similar, which is currently the case in the US, terbinafine, as an allylamine, may be preferable. Is terbinafine also the preferable treatment when oral treatment is required? Terbinafine was superior to griseofulvin in achieving mycological cure and has the advantage of healing more quickly. When studied head to head with itraconazole, higher cure rates were reported for terbinafine, but only 1 of 4 studies showed a statistically significant difference.
The drawbacks are, of course, cost and side effects. In the US, a 2 week course of terbinafine, 250 mg/day, or itraconazole, 100 mg/day, costs about US $100.2 Compare this with the cost of topical treatment with azoles or allylamines at about $14 for 1 week of treatment. Frequent side effects of systemic treatment include diarrhoea and nausea. However, no long term side effects were reported in any of the studies included in the review. Overall, terbinafine, and perhaps other allylamines, are more effective than azoles, but not dramatically so. This pokes more holes in the commonly held perception that terbinafines in all forms are superior to azoles in treating tinea pedis.3 Future work needs to address the comparative effectiveness of topical and oral treatments for tinea pedis.
Source of funding: not stated.
For correspondence: Ms S Bell-Syer, University of York, York, UK. sembs1{at}york.ca.uk
A modified version of this abstract appears in ACP Journal Club.


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Team Audit | Player Cards | Depth Chart
|Return to Top
Acquired RHPs Angel Sanchez, Steve Ames, and Josh Wall from the Dodgers for RHP Ricky Nolasco and International Bonus Slot 4. [7/6]
The Marlins added three pitchers with varying degrees of arm strength. The top prospect in the deal is 23-year old right-hander Angel Sanchez. Sanchez has a chance to remain a starter, with three pitches that could all rate at least average. His fastball sits in the low 90s and bumps 94 with improving control, and his slider and changeup have both flashed average according to scouts in the Midwest League this summer. Sanchez still has plenty of development remaining but he has the ceiling of a no. 4 starter.
The Marlins also add two middle relief prospects in right-handers Steve Ames and Josh Wall. Ames drew plenty of praise after a lights out performance in the Double-A Southern League in 2012, and he was added to the 40-man roster as a result. He has continued to find success in Triple-A this year, firing fastballs in the low 90s and sliders that flash in the solid-average range. Both pitches can work at the big-league level but lack the crispness to miss bats in high-leverage situations.
Wall has arguably the best pedigree of the group, having been popped by the Dodgers in the second round of the 2005 draft. With a 12.08 ERA in 12 2/3 big-league innings over the past two seasons, Wall has yet to gain consistency with his power fastball and slider. He can reach back for 94-95 mph when he needs it and sits in the 91-92 mph range during most relief outings. His slider can be a true plus pitch at its best. Wall's control and command lag behind the rest of his game, resulting in too many pitches over the heart of the plate. Barring a sudden and very unlikely leap forward in his command, Wall profiles in the middle innings, similar to Ames. —Mark Anderson
The Marlins held one of the market's most widely sought-after trade chips, auctioned him off early, and bundled him with $197,000 of international bonus money (which otherwise would have ended up under their mattress). In return, they received a package highlighted by a pitcher whose ceiling is another Nolasco. Given the scarcity of serviceable starters and the number of teams that need one, the Marlins likely could have acquired a promising prospect had they prioritized talent. Instead, they prioritized not paying Nolasco, and with the Dodgers picking up the $5.5 million still owed him this season, a trio of low-upside arms was the best they could do. The Marlins have done a good job of developing whatever young talent comes their way, but there's not a lot to work with here.
This is business as usual in Miami, where Nolasco's $11.5 million full-season salary has made him a marked man since the latest firesale started. Now that the 30-year-old righty—who, somewhat sadly, holds most of the Marlins' franchise pitching records, at least when it comes to counting stats—is officially a former Fish, Adeiny Hechavarria and Placido Polanco, each of whom is collecting $2.75 million, take over as the team's top earners. The Players Union is probably already drafting a complaint to send to Bud Selig in the event that Jeffrey Loria tries to carry his current payroll into 2014. And a few more fans who might have paid to see the Marlins in the second half—with the team's average attendance already down over 10,000 per game—have probably decided to stay home. —Ben Lindbergh
Team Audit | Player Cards | Depth Chart
|Return to Top
Acquired RHP Ricky Nolasco and International Bonus Slot 4 from the Marlins for RHPs Angel Sanchez, Steve Ames, and Josh Wall. [7/6]
Were it not for Chris Capuano's two most recent starts, in which he allowed 11 runs in eight innings, the Dodgers might have opted against trading three arms for Nolasco and absorbing what remains of his salary. But those disastrous outings preceded, and perhaps caused, a deal in which the Dodgers receive a capable no. 4 starter and cap leeway for their international efforts.
Nolasco brings a deep arsenal and strike-throwing tendencies to the table. His fastball tops out in the low 90s, and he seems self conscious about it. During a recent start versus St. Louis he threw six fastballs over a two-inning, 21-pitch stretch and instead filled the zone up with his splitter, curveball, and slider. This backward approach can get messy, as it necessitates control over all of the offerings, which can lead to inconsistency.
The good news for Nolasco is that he fits better with his hometown team than he did with the Marlins. He can take comfort in knowing that the Dodgers have Clayton Kershaw, Zack Greinke, and Hyun-jin Ryu to hold down the front three spots in the rotation. That leaves Nolasco as the club's fourth starter, with either Capuano or Stephen Fife—the statistical favorite—to bring up the rear and battle for a possible playoff start.
If Nolasco appears more at home in Los Angeles, expect to hear about how he needed a change of scenery. This belief existed even before the trade, as there's some thought in the industry that he could improve in the right situation and under the right coaching staff. Whether the Dodgers meet those conditions is unknown. More certain is Nolasco's impending free agency. These few months out west may determine whether Nolasco signs a comfortable multi-year deal or takes something shorter in term and dollars.
In the interim, Nolasco represents an upgrade over the loser of the Dodgers' rotation situation, and as a result improves their playoff odds. Given the opportunity cost involved, it's hard to find fault with the Dodgers' side of this deal. —R.J. Anderson
Team Audit | Player Cards | Depth Chart
|Return to Top
Reportedly acquired OF-R Scott Hairston and a player to be named later from the Cubs for RHP Ivan Pineyro and a player to be named later. [7/7]
It's hard to believe that Hairston caused such a stir as a free agent over the winter, in light of how little he's played. After a career-high 134 games in 2012, the 33-year-old started just 25 of the Cubs' first 86 contests this season, mostly spelling Nate Schierholtz against southpaws. And despite being protected from righties more often than ever—nearly 80 percent of his plate appearances with the Cubs came against lefties—Hairston is hitting only .172.
But that average is somewhat deceptive, both because he's been subject to the pinch-hit penalty—Hairston is 5-for-23 off the bench, though he went out on a high note with a seventh-inning homer on Sunday—and because his secondary offensive skills still seem intact. Hairston has swung, walked, made contact, and K'd at roughly his career rates, and after several seasons in parks where it's hard for right-handers to homer, his ISO benefited from a relocation to Wrigley, where he hit seven of his eight homers.
The production the Nats got out of bench bats like Roger Bernadina, Steve Lombardozzi, Tyler Moore, and Chad Tracy was a big factor behind their 2012 success, but those same players have been offensive zeroes this season. Hairston, who's signed through next season and has hit as many homers as those four players combined, will take Tyler Moore's place, giving the Nats the power pinch-hitter they've lacked, as well as a more palatable replacement for Bryce Harper in the event that they ever persuade him to take a day off. Nationals Park isn't as easy on righties as Wrigley, but it's a cakewalk compared to Petco, the Coliseum, and Citi Field.
The NL Central has a shortage of southpaw starters—the Cardinals and Brewers have all-righty rotations, as will the Reds when Johnny Cueto returns—so the division switch might help Hairston get into more games (though the Mets and Marlins also lack lefties). He won't have to wait long to see action, since the Nats will face lefties John Lannan, Cole Hamels, and Cliff Lee in the first three games of a four-game set against the Phillies that starts today. —Ben Lindbergh
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For Scheme code, the fundamental procedure to react to non-local entry
and exits of dynamic contexts is
dynamic-wind. C code could
scm_internal_dynamic_wind, but since C does not allow the
convenient construction of anonymous procedures that close over
lexical variables, this will be, well, inconvenient.
Therefore, Guile offers the functions
scm_dynwind_begin and
scm_dynwind_end to delimit a dynamic extent. Within this
dynamic extent, which is called a dynwind context, you can
perform various dynwind actions that control what happens when
the dynwind context is entered or left. For example, you can register
a cleanup routine with
scm_dynwind_unwind_handler that is
executed when the context is left. There are several other more
specialized dynwind actions as well, for example to temporarily block
the execution of asyncs or to temporarily change the current output
port. They are described elsewhere in this manual.
Here is an example that shows how to prevent memory leaks.
/* Suppose there is a function called FOO in some library that you would like to make available to Scheme code (or to C code that follows the Scheme conventions). FOO takes two C strings and returns a new string. When an error has occurred in FOO, it returns NULL. */ char *foo (char *s1, char *s2); /* SCM_FOO interfaces the C function FOO to the Scheme way of life. It takes care to free up all temporary strings in the case of non-local exits. */ SCM scm_foo (SCM s1, SCM s2) { char *c_s1, *c_s2, *c_res; scm_dynwind_begin (0); c_s1 = scm_to_locale_string (s1); /* Call 'free (c_s1)' when the dynwind context is left. */ scm_dynwind_unwind_handler (free, c_s1, SCM_F_WIND_EXPLICITLY); c_s2 = scm_to_locale_string (s2); /* Same as above, but more concisely. */ scm_dynwind_free (c_s2); c_res = foo (c_s1, c_s2); if (c_res == NULL) scm_report_out_of_memory (); scm_dynwind_end (); return scm_take_locale_string (res); }
All three arguments must be 0-argument procedures. in_guard is called, then thunk, then out_guard.
If, any time during the execution of thunk, the
dynamic extent of the
dynamic-wind expression is escaped
non-locally, out_guard is called. If the dynamic extent of
the dynamic-wind is re-entered, in_guard is called. Thus
in_guard and out_guard may be called any number of
(define x 'normal-binding) ⇒ x (define a-cont (call-with-current-continuation (lambda (escape) (let ((old-x x)) (dynamic-wind ;; in-guard: ;; (lambda () (set! x 'special-binding)) ;; thunk ;; (lambda () (display x) (newline) (call-with-current-continuation escape) (display x) (newline) x) ;; out-guard: ;; (lambda () (set! x old-x))))))) ;; Prints: special-binding ;; Evaluates to: ⇒ a-cont x ⇒ normal-binding (a-cont #f) ;; Prints: special-binding ;; Evaluates to: ⇒ a-cont ;; the value of the (define a-cont...) x ⇒ normal-binding a-cont ⇒ special-binding
This is an enumeration of several flags that modify the behavior of
scm_dynwind_begin. The flags are listed in the following
The dynamic context is rewindable. This means that it can be reentered non-locally (via the invocation of a continuation). The default is that a dynwind context can not be reentered non-locally.
void scm_dynwind_begin
(scm_t_dynwind_flags flags) ¶
The function
scm_dynwind_begin starts a new dynamic context and
makes it the 'current' one.
The flags argument determines the default behavior of the
context. Normally, use 0. This will result in a context that can not
be reentered with a captured continuation. When you are prepared to
handle reentries, include
SCM_F_DYNWIND_REWINDABLE in
Being prepared for reentry means that the effects of unwind handlers can be undone on reentry. In the example above, we want to prevent a memory leak on non-local exit and thus register an unwind handler that frees the memory. But once the memory is freed, we can not get it back on reentry. Thus reentry can not be allowed.
The consequence is that continuations become less useful when non-reentrant contexts are captured, but you don't need to worry about that too much.
The context is ended either implicitly when a non-local exit happens,
or explicitly with
scm_dynwind_end. You must make sure that a
dynwind context is indeed ended properly. If you fail to call
scm_dynwind_end for each
scm_dynwind_begin, the behavior
is undefined.
void scm_dynwind_end
() ¶
End the current dynamic context explicitly and make the previous one current.
This is an enumeration of several flags that modify the behavior of
scm_dynwind_unwind_handler and
scm_dynwind_rewind_handler. The flags are listed in the
following table.
The registered action is also carried out when the dynwind context is entered or left locally.
void scm_dynwind_unwind_handler
(void (*func)(void *), void *data, scm_t_wind_flags flags) ¶
void scm_dynwind_unwind_handler_with_scm
(void (*func)(SCM), SCM data, scm_t_wind_flags flags) ¶
Arranges for func to be called with data as its arguments
when the current context ends implicitly. If flags contains
SCM_F_WIND_EXPLICITLY, func is also called when the
context ends explicitly with
The function
scm_dynwind_unwind_handler_with_scm takes care that
data is protected from garbage collection.
void scm_dynwind_rewind_handler
(void (*func)(void *), void *data, scm_t_wind_flags flags) ¶
void scm_dynwind_rewind_handler_with_scm
(void (*func)(SCM), SCM data, scm_t_wind_flags flags) ¶
Arrange for func to be called with data as its argument when
the current context is restarted by rewinding the stack. When flags
SCM_F_WIND_EXPLICITLY, func is called immediately
as well.
The function
scm_dynwind_rewind_handler_with_scm takes care that
data is protected from garbage collection.
void scm_dynwind_free
(void *mem) ¶
Arrange for mem to be freed automatically whenever the current
context is exited, whether normally or non-locally.
scm_dynwind_free (mem) is an equivalent shorthand for
scm_dynwind_unwind_handler (free, mem, SCM_F_WIND_EXPLICITLY).


text:
New online course for RLI trainers now available
A new online course is now available offering training for experienced professionals wishing to train and support others to implement the Reading and Language Intervention for Children with Down Syndrome (RLI).
The Reading and Language Intervention for Children with Down Syndrome (RLI) is an evidence-based program designed to teach reading and language skills to children with Down syndrome. Evaluated in 50 schools in a randomized controlled trial, the intervention is designed to be delivered by teaching assistants in daily one-to-one sessions, supported by the class teacher and school SEN specialists.
Although many schools implement RLI successfully using the intervention handbook, some seek additional support and training for their staff. In some areas, Down syndrome support groups provide additional support and training for schools. In other areas, learning support services have developed expertise supporting schools.
This online course is designed for experienced teachers, educational psychologists and speech language pathologists who wish to provide accredited training and support for RLI. Professionals who successfully complete this course can choose to enrol as accredited trainers who may use DSE-supplied training materials and can be recommended to schools and groups requesting training and support in local areas.


text:
The Two Sides of Perception
Richard Ivry is Professor in the Department of Psychology at the University of California Berkeley.
Lynn Robertson is Adjunct Professor Emerita in the Department of Psychology at the University of California, Berkeley.
Anatomically, the central nervous system looks remarkably symmetrical—from the relatively simple structures of the spinal cord to the extensively convoluted folds of the cerebral hemispheres. At the functional level, however, there are striking differences between the left and right hemispheres. Although popular writings attribute language abilities to the left hemisphere and spatial abilities to the right, differences in hemispheric function appear to be more subtle. According to Ivry and Robertson, asymmetries over a wide range of perceptual tasks reflect a difference in strength rather than kind, with both hemispheres contributing to the performance of complex tasks, whether linguistic or spatial.
After an historical introduction, the authors offer a cognitive neuroscience perspective on hemispheric specialization in perception. They propose that the two hemispheres differ in how they filter task-relevant sensory information. Building on the idea that the hemispheres construct asymmetric representations, the hypothesis provides a novel account of many laterality effects. A notable feature of the authors' work is their attempt to incorporate hemispheric specialization in vision, audition, music, and language within a common framework. In support of their theory, they review studies involving both healthy and neurologically impaired individuals. They also provide a series of simulations to demonstrate the underlying computational principles of their theory. Their work thus describes both the cognitive and neurological architecture of hemispheric asymmetries in perception.
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text:
Rajwari Ring 09
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