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Check out the new Easy Avocado Toast Recipe.
Last week I was very excited to find 11 new recipes for eggs contributed to the Friday Foodie Fix. I hope with a weeks' notice that we will have even more ideas for Secret Ingredient, avocados. I love avocados and I'm always looking for new ways to use them in recipes. Remember, these can be past recipe posts you've made and you can post more than one recipe for each Secret Ingredient. Why limit yourself to just one.
Avocados are a fruit native to the Caribbean, Mexico, South and Central America. Each fruit contains 10 grams of fiber and is packed with potassium. The creamy green fruit also provides Vitamin C, A, B6, copper, iron, magnesium and pantothenic acid, which helps your body convert food into energy. There are many types of avocados on the market but my favorite is the Haas. All Haas avocado trees are descended from a single "mother tree" planted by Rudolph Haas in 1926 in La Habra Heights, California.
When purchasing an avocado make sure it is ripe. It should be soft when you squeeze it but not so soft one squeeze and you have just made guacamole. If it is not ripe when you purchase it place it in a paper bag for a few days. When you cut an avocado, it will discolor fast. It avoid this, squeeze it with a little lime juice.
To pit an avocado, use a sharp knife and cut around the avocado in half lengthwise creating a circle. You will feel your knife run around the pit. Twist the halves in opposite direction and they will part. One side will be left with the pit. Cleave your knife blade into the pit and twist the seed, it will pop out. Be careful as you remove the pit from your knife. While still gripping the knife with the pit I use my thumb holding the knife to slide it off. You can also slide the blade on the edge of a bowl to knock it off.
To dice the avocado, make a crosshatch pattern through the avocado being careful to not penetrate the skin. Then you can scoop out the cubes with a tablespoon. To mash, use a fork or a potato masher.
You can also use my favorite guacamole tool.
My Friday Foodie Fix recipe is Pan Fried Bacon Wrapped Avocados and yes they are delicious.
Thank you for sharing your Friday Foodie Fix of avocados with us. It would very cool of you to link this back to your post on avocados too. Here are the rules. Have a great weekend!
Next week's Secret Ingredient is ……………. Asparagus!
My husband groaned and asked, "How many people really eat asparagus?" Well, let's show him!


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I met Donna when we worked together in the travel industry, and we reconnected a few years ago at an airline reunion. Once a traveller, always a traveller, and Donna decided to celebrate her birthday in Venice. I didn't want our Vancouver friends to miss out on all the fun, so I hosted a 4-6 p.m. Happy (Birthday) Hour for about a dozen guests.
Beverages were the first order of business. I made Jargaritas (frozen margaritas served in jars) and picked up three 1.5 L bottles of Mateus Rosé, that 1970s frizzante wine that tastes like a day at the beach.
Donna's favourite, devilled eggs, topped the appetizer list. I took a shortcut and ordered a platter of them, but I'm sharing a recipe for a clever vertical version that will lend a fresh look to your next cocktail party.
I served two platters — a Mediterranean spread with smoked hummus, mixed olives, cornichons, preserved lemon, balsamic onions and pita plus a crudité tray with sour cream herb dip. My bacon-crusted cheddar bake filled the hot-bite slot.
As I recount it here, that sounds like plenty of food, but I still panicked about running out, so a friend picked up two trays of sushi from Fujiya on Clark Drive. You don't usually have dessert at a Happy Hour, but I was craving Twixter Bars and Lemon Squares from the Dirty Apron Cooking School and Deli, so ordered a batch of them.
It's a good thing I erred on the side of excess: The last guests left at 11 p.m.
You will need a dozen 8-ounce glass canning jars with lids. I buy them at the Dollar Store.
1 — 12oz (355 mL) can frozen limeade concentrate, thawed
Juice of 2 limes
1 1/2 cups tequila
¾ cup Triple Sec
1 cup Chambord or red raspberry liqueur
4 cups cold water
Combine all the ingredients in a large pitcher and stir well. Divide the mixture among 12 8-ounce jars, filling them to within ½ inch of the rim. Place the lids on the jars and screw them on fairly tightly. Freeze overnight or for at least 5 hours.
You may serve the Jargaritas with spoons or simply instruct you guests to warm them in their hands until they are slushy enough to sip.
Makes 12 servings
Vertical Devilled Eggs
Organic eggs are an affordable luxury that makes you feel indulgent and healthy at the same time. (Adapted from On Boards: Simple & Inspiring Recipe Ideas to Share at Every Gathering by Lisa Dawn Bolton, Appetite by Random House, 2018.)
12 extra-large organic eggs, hard cooked and chilled (see Kitchen Hack)
1/4 cup crème fraîche
2 tbsp full-fat mayonnaise
2 tsp Dijon mustard
Pinch cayenne
½ tsp flaked sea salt
Sweet paprika and minced chives for garnish (optional)
Carefully peel the eggs. (Slide a small spoon under the shell if it sticks.) Cut a small slice from the more rounded of the two ends of each egg so they stand upright.
Slice a quarter to a third off the top of each egg. Use a small spoon or the handle of a teaspoon to scoop out the yolks. Place them in a small bowl along with the trimmed whites. Mash them with a fork, working in the crème fraîche, mayonnaise, mustard, cayenne and salt.
Use a spatula to scoop the filling into a medium-size piping bag fitted with a small round tip. (Or use a medium-size resealable plastic bag, snipping a small hole in one corner.) Pipe the filling into each standing egg white.
Garnish the eggs, if you wish, with a sprinkle of paprika and chopped chives. The eggs may be refrigerated in an airtight container for up to 3 days.
Makes 12 servings
Kitchen Hack: Hard-Cooked Eggs
Place the eggs in a single layer in a pot, cover with cold water and bring just to a boil. Reduce the heat to a bare simmer and cook the eggs, partially covered, for 8 to 10 minutes. Immediately drain off the cooking water, run cold water over the eggs and add ice cubes to the pot to cool them as rapidly as possible.
Copyright Postmedia Network Inc., 2019

subset: commoncrawl


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MSRA Back To The 50's Show - Back '50's To The Weekend
It's Sturgis For Hot Rod Trucks
Related Video
The summertime is the right time for hopping in the cab of your truck and hitting the road, but unfortunately there's a million different events all going on at the same time. A case in point was the weekend of June 21, the first week of summer when the MSRA folks were throwing their 36th annual Back to the '50's event. On the same date out in California, not more than 10 miles away from our Placentia offices, the 27th annual F-100 Western Nationals were taking place, and just a little farther north, the L.A. Roadsters were holding their 45th annual show. It was a shame to miss 'em but Tim Bernsau and I had been talking about hitting Back to the '50's for some time, so we decided this year was going to be the year we went. What a great time we had, it was like climbing into a time machine and going back 50 years in time.
Back to the '50's Weekend is held on the 320-acre grounds of the Minnesota State Fair which opened for the first time on September 7, 1885, so as one can imagine there's a lot of great old buildings, and established landscaping to make it the perfect venue to hold over 100,000 attendees and over 11,500 vehicles. For information about next year's show please check out www.msra.com.
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British police arrest two men on diverted Pakistan flight
Fighter jet scrambled after threats made aboard diverted Pakistan plane
Britain scrambled fighter jets on Friday to intercept a commercial airliner carrying more than 300 people from Pakistan, diverting it to an isolated runway at an airport on the outskirts of London and arresting two passengers on suspicion of endangering the aircraft.
A British security official said the situation involving the Pakistan International Airlines flight did not appear terror-related, though police were still investigating, but the incident further rattled Britain just days after a soldier was killed on a London street in a suspected terror attack.
Two men were arrested on suspicion of endangering an aircraft on Friday after a British fighter jet was scrambled to divert their plane as it travelled from Pakistan to Britain, officials said. The incident further rattled the United Kingdom just days after a British soldier was brutally killed on a London street in a suspected terror attack.
A British security official said the situation involving the Pakistan International Airlines flight, which carried more than 300 people, did not appear to be terror-related, but that police were still investigating. He requested anonymity because he was not authorised to discuss the investigation.
A fighter jet was launched to divert Flight P709 – which was supposed to travel from Lahore to Manchester – to Britain's Stansted Airport, where it was kept on an isolated runway. Essex Police said two suspects, ages 30 and 41, were taken to a police station for questioning.
Passenger Nauman Rizvi told Pakistan's GEO TV that two men who had tried to move toward the cockpit during the flight were handcuffed and arrested once the plane landed. Rizvi said that after the men were taken away, the flight crew told passengers there had been a terrorist threat and that the pilot had raised an alarm.
PIA spokesman Mashood Tajwar said the airline had been unable to contact the pilot of the flight despite repeated attempts. He said 297 passengers and 11 crew members were on the plane. Tajwar added that the control tower at Manchester airport received a call about a threat aboard the plane and the tower advised the pilot to divert to Stansted.
Britain's Defence Ministry confirmed that a Typhoon jet was launched to investigate an incident involving a civilian aircraft but declined to give further details.
By late afternoon on Friday, the passengers had disembarked from the plane and were being interviewed, according to Mark Davison, a spokesman for Stansted Airport.
The incident comes as many police forces across Britain have stepped up patrols in recent days following a suspected terror attack in south London.
Two men with meat cleavers attacked and killed a British soldier in broad daylight, and gruesome footage that emerged after the attack showed one of the alleged assailants angrily complaining about the British government and troops in foreign lands.
Those two suspects were shot when police arrived on the scene and have been hospitalised.


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HDRI Skydome 47 is a full 360° panoramic image in .HDR and .EXR-format to be used as spherical environment and light dome in 3d scenes. Several exposure images were taken with a Nikon camera with neutral density filters and a professional lens to ensure sharpness and avoid lens distortion. The skydome includes backplate images of the sky to be used as background for more flexibility.
DIRECTIONAL PREVIEWS (ROTATED in 30° STEPS)
360° panoramic preview
Dynamic Range
The dynamic range of app. 19 EVs (Exposure Values) provides high quality results with sharp shadows and accurate lighting.
included backplates
The skydome includes 10 backplates photographs of the sky taken at the same time from different angles. All backplates have a resolution of 7k (7360 x 4912 pixel), good even for hires renders.
Technical Details
- One 360° skydome high-dynamic-range panorama in .HDR and .EXR format
- 20k HDRI resolution: 19.690 x 9.845 pixel (highly detailed, suitable as background as well)
- Dynamic Range: app. 19 Exposure Values
- 10 backplate sky photos (JPG and DNG Digital Negative)


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(AllHipHop News) The family of Bob Marley has announced the first ever authorized documentary on the singer will be in theaters this April.
Magnolia Pictures has teamed with VH1 to obtain the United States rights to Academy award-winning director Kevin McDonald's documentary "Marley."
"Marley" is being executive produced by Island Records' founder Chris Blackwell, as well as Bob Marley's son Ziggy Marley.
The documentary will make its world premiere at the 62nd Berlin International Film Festival in February, and will premiere in North America, at SXSW this March.
"This documentary is the ultimate revelation of my father's life," Executive Producer Ziggy Marley told AllHipHop.com in a statement today (February 6), on what would have been his father's 67th birthday.
"The family is proud to be able to have the world finally experience this emotional journey," Ziggy Marley said.
"Marley" is the first official autobiography to tell the definitive life of Bob Marley, who was a musician, political activist and father.
The documentary is comprised of rare footage, archival photos and interviews with family, friends and bandmates.
Marley, who was posthumously inducted into the Rock and Roll Hall of Fame in 1994, is a best selling artist around the world.
His compilation album Legend has sold over 10 million copies around the world by itself, while his Facebook page has over 35 million fans.
Bob Marley was born Robert Nesta Marley on February 6, 1945.
He's the son of white quartermaster Captain Norval Marley of the British West Indian Regiment and an eighteen-year old black Jamaican woman, Cedella Malcolm.
He died on May 11, 1981, at the age of 36, from melanoma cancer.
"Marley" is slated to open in theaters and all VOD and digital platforms on Friday, April 20th.
"Bob Marley is a fascinating, towering figure in musical history, and 'Marley' is the biography that he deserves," said Magnolia President Eamonn Bowles. "Kevin Macdonald has once again shown himself to be a master documentarian with this eye-opening, entertaining, beautifully crafted film."
VH1 has licensed the documentary through their Emmy-Award winning VH1 Rock Doc franchise.


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NEW YORK Wed May 21, 2014 3:59pm EDT
(Reuters Health) - In a new study, children who regularly got too little sleep had worse physical, emotional and social health than those who slept the average amount.
"Sleep is important for a lot of reasons, and can influence health and well-being and cognitive functioning," said lead author Christopher A. Magee. "The typical sleep pattern appeared to have the best outcomes as measured in this paper," he told Reuters Health in an email.
But since this is a relatively new area of research, the researchers can't say for sure that this pattern of sleep causes better health and wellbeing, said Magee, of the University of Wollongong in Australia.
Genetics do influence the regulation of sleep, but the results suggest that environmental and social factors, like household financial hardship, may play a role as well, he said.
The researchers used Medicare Australia data from a group of almost 3,000 children to track the kids' health and quality of life at four points between birth and seven years of age.
Parents completed sleep journals and answered interview questions about their children's sleep patterns, and included how often their children had experienced problems like difficulty waking, feeling sad, problems socializing or missing school due to illness, which were meant to rate the child's overall quality of life.
Researchers divided the kids into four groups based on their sleep patterns: "typical sleepers" slept the most as infants, about 14 hours, and gradually decreased their sleep duration until age seven, when they got an average of almost 11 hours per night.
"Persistent short sleepers" showed a similar decline in sleep hours over time, but they always got about an hour less sleep than the typical sleepers. Only 11 percent of kids fell into this group.
"Initially short sleepers" started out like the short sleepers, but by age five or six were getting as much sleep as typical sleepers. This group included 45 percent of the kids, followed by typical sleepers, who made up 40 percent.
Less than three percent of kids had the most unusual sleep pattern, which started short, with sleeps of less than 10 hours in infancy, gradually increasing with time. Researchers called this group the "poor sleepers."
Poor and initially short sleepers tended to have a lower physical functioning score on the quality of life scale than typical sleepers. Persistent short sleepers also had the physical disadvantage, as well as lower emotional and social functioning scores, according to the results published in Pediatrics.
Following one group of kids for seven years helps to focus on the problem of too little sleep as a chronic issue, not just one bad night, said Dr. Elsie M. Taveras, director of Pediatric Population Health Management at Massachusetts General Hospital in Boston.
Taveras worked on a similar study published in the same issue of the journal, following 1,000 kids from age six months to seven years, and found that kids who chronically slept too little tended to have more body fat at age seven than longer sleepers.
Kids who had shortened sleep most often were more than twice as likely to be obese than kids who rarely or never had short sleep duration. That's a significant increase in risk, she said.
"Two times the odds of obesity for any risk factor for obesity is very rare," she said.
In Taveras' study, short sleepers not only had more fat, but more abdominal fat than longer sleepers.
"Abdominal fat is particularly hazardous for later cardiometabolic diseases," like diabetes and heart disease, she told Reuters Health by phone.
Taking the results of her study with the results of the Australian quality of life study, the amount of sleep kids get seems to be linked to a huge number of areas of health, she said.
According to recommendations from the National Sleep Foundation and the National Heart, Lung and Blood Institute, toddlers need more than 12 hours of sleep per day, children up to four years old need between 10 and 11 hours and up to age seven kids should get at least 10 hours, Taveras said.
"For many children, good sleep could be promoted by having regular bedtimes, limiting household noise, and limiting TV viewing and electronic media near bedtime," Magee said, but some sleep problems like sleep apnea or primary insomnia may need specialized treatment.
"If a child has persistent problems sleeping and this is impacting on their normal daily activities, then it may be a good idea to seek some advice," he said. "A general practitioner could be a good starting point."
SOURCE: bit.ly/1gGJ0KR and bit.ly/1vsqt9h Pediatrics, May 19, 2014.
Copyright 2012 Thomson Reuters. Click for Restrictions.


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Other Research and Publications: Betty-Anne Davis / Kenneth C. Johnson
Publications by Betty-Anne Daviss
Lalonde, Andre. Daviss, BA. Acosta, A. Herschderfer, K. Postpartum Hemorrhage Today: ICM/FIGO Initiative 2004-2006. The World Report. International Journal of Gynecology and Obstetrics. 2006. 94:243-253.
Daviss, BA, From Calling to Career: Keeping the Social Movement in the Professional Project. in MAINSTREAMING MIDWIVES: THE POLITICS OF CHANGE. Eds. Robbie Davis-Floyd and Christina Johnson. New York: Routledge, 2005: 413-446.
Daviss BA, Hungarian Women Unveil An Ironic Curtain (Obstetrics in Eastern Europe), Midwifery Today (68), Winter 2003. This is a paper applying social movement theory to the struggles in Hungary between the Obstetric Society of Hungary and the midwives pushing for undisturbed and home birth.
Johnson K and Daviss BA, Letter to the editor re Outcomes of Planned Home Births in Washington State: 1989-1996". The American College of Obstetricians and Gynecologists (101), 1. Jan. 2003. A critical letter to demonstrate that a home birth study conducted in Washington state has not met the sophisticated standard of modern home birth research.
Daviss BA, Studys Focus on Induction vs spontaneous labour neglects spontaneous delivery, Letter to the editor re Vaginal delivery after caesarean section. The British Medical Journal, (323), 1307, December 1, 2001. Response to a study being used across the U.S. and Canada to decrease the number of women having vaginal births after cesareans.
Daviss BA, Reforming birth and (re)making midwifery in North America, in Birth By Design, eds. DeVries, R., Teijlingen, E., Wrede, S. and Benoit, C. New York: Routledge, 2001. Betty-Anne collaborated with social scientists from northern Europe and North America to create this anthology demonstrating how differently maternity care services have developed across the two continents. Also authored one chapter and co-authored a second.
Daviss BA Why Are Health Care Professionals Embarrassed to Be Connected With Social Movements? Alternative Futures and Popular Protest, eds. Barker, C. and Tyldesley, M., Conference Papers of the Sixth International Conference, Vol. 1, Manchester Metropolitan University, England, April 25-27, 2000. Gathering of social activists and academics from across Europe, South and North America, discussing strategies, successes, and difficulties of social movements.
Daviss BA From Social Movement to Professional Midwifery Project: Are we Throwing the Baby Out with the Bath Water? MA thesis, Graduate Department of Canadian Studies, Carleton University, Ottawa, 1999.
Daviss BA Heeding Warnings from the Canary, the Whale and the Inuit, A Framework for Analyzing Competing Types of Knowledge About Childbirth, in eds. Robbie Davis-Floyd and Carolyn Sargeant, Childbirth and Authoritative Knowledge. California: University of California Press, 1997.
Publications by Kenneth C. Johnson
Johnson KC and Daviss BA. Re: Results of the National Study of Vaginal Birth After Cesarean in Birth Centers. Obstet Gyn April 1, 2005; 105(4): 897 - 898.
Johnson KC and Daviss BA. Re: Outcomes of planned home births in Washington State: 1989-1996. Obstet Gyn 2003 Jan; 101(1):198
Johnson KC, Gaskin IM. Safety of single-layer suturing in caesarean sections must be proved. BMJ 2001; 323:1307.
Johnson KC. Randomized Controlled Trials as Authoritative Knowledge: Keeping an Ally From Becoming A Threat to North American Midwifery Practice - book chapter, Davis Floyd, R (ed)) Authoritative Knowledge In Childbirth - University of California Press, 1997.
Johnson KC, Rouleau J. Temporal Trends in Canadian Birth Defects Birth Prevalence, 1979-1993. Can J of Pub Hlth: 88(3), 169-176. 1997.
Rouleau J, Arbuckle TE, Johnson KC, Gregory J Sherman, Status Report: Description and Limitations of the Canadian Congenital Anomalies Surveillance System (CCASS). Chronic Diseases in Canada. Vol 16, No 1, Winter 1995.
Sherman GJ, Sweet L, Kermode DJ, Johnson KC, Lavigne PM. Congenital Birth Defects in Cape Breton County, Nova Scotia, 1979 - 1982. Chron Dis Canada Special Report No. 10, August, 1985.
Jain M, Howe GR, Johnson KC, Miller AB. Evaluation of a Diet History Questionnaire for Epidemiologic Studies. American Journal of Epidemiology; 212 - 219, 1980.
Other Epidemiologic Publications
Johnson KC. Pedestrian Deaths in Canada, Chronic Diseases in Canada, 1983(4)
Johnson KC, Mao Y, Argo J, Robert Semenciw, Environment-Related Cancer Surveillance in Canada. Proceedings of International Congress on Hazardous Waste: Impact on Human and Ecological Health, June 5-8, 1995, Atlanta, Georgia.
Johnson KC. Canadian Health Databases Relevant to Great Lakes Basin Research. Toxicology and Industrial Health, Vol. 12, Nos. 3/4, 1996. Hu J, Johnson KC, Mao Y, Xu T, Lin Q, Wang C, Zhao F, Wang G, Chen Y, Yang Y. A Case-Control Study of Diet and Lung Cancer in Northeast China. Int. J. Cancer: 71, 924-931. 1997.
Hu J, Johnson KC, Mao Y, Guo L, Zhao X, Jia X, Bi D, Huang G, Lui R. Risk Factors for Glioma in Adults: A Case-Control Study in Northeast China, Cancer Detection and Prevention: 22(2); 100-108. 1998.
Johnson KC, Mao Y, Argo J, Dubois S, Semenciw R, Lava J and The Canadian Cancer Registries Epidemiology Research Group. The National Enhanced Cancer Surveillance System: A Case-control Approach to Environment-Related Cancer Surveillance in Canada. Environmetrics: 9,495-504. 1998.Mills CJ, Bull RJ, Cantor K, Reif J, Hrudey S and the expert working group (including Johnson KC). Health Risk of drinking water chlorination by-products: Report of an expert working group. Chronic Diseases in Canada 1998; 19(3):91-102.
Villeneuve PJ, Johnson KC, Kreiger N, Mao Y, and The Canadian Cancer Registries Epidemiology Research Group. Risk factors for prostate cancer: results from the Canadian National Enhanced Surveillance System. Cancer Causes and Control. 10: 355-367. 1999.
Johnson KC. National Enhanced Cancer Surveillance System: A Federal-Provincial Collaboration to Examine Environmental Risks - Status Report Chronic Diseases in Canada. 21(1): 34 -35. 2000.
Parkes R, Kreiger N, James B, Johnson KC. Effects On Response Rates Of Information Brochures And Small Cash Incentives In A Mail-Based Case-Control Study. Annals of Epidemiology. 10(2):117-124. 2000.
Johnson KC, Hu J, Mao Y and The Canadian Cancer Registries Epidemiology Research Group. Passive and Active Smoking and Breast Cancer Risk in Canada 1994-97. Cancer Causes and Control. 11: 211-221. 2000. Johnson KC, Repace J. Re: Publication Bias and Passive Smoking and Lung Cancer - Turning over the wrong stone. BMJ 321:1221. 2000.
Villeneuve PJ, Johnson KC, Hanley AJG, Mao Y, and The Canadian Cancer Registries Epidemiology Research Group. Alcohol, tobacco and coffee consumption and the risk of pancreatic cancer: results from the Canadian Enhanced Surveillance System case-control project. European J Cancer Prev. 9:49-58. 2000.
Johnson KC Re: Breast Cancer-epidemiology, risk factors and genetics. BMJ. 322:365.2001
Johnson KC. Re: Passive smoking and female breast cancer mortality. J Natl Cancer Inst. 93(9):719-20.2001
Johnson KC, Hu J, Mao Y and The Canadian Cancer Registries Epidemiology Research Group. Lifetime residential and occupational exposure to environmental tobacco smoke and lung cancer in never -smoking women, Canada 1994-97. Int J Cancer 2001, 93:902-6.
Johnson KC, Mao Y. National stroke surveillance program needed in Canada. CMAJ. 2001 Oct, 2; 165(7):886-7.
Hanley AJG, Johnson KC, Villeneuve PJ, Mao Y and The Canadian Cancer Registries Epidemiology Research Group. Physical activity, anthropometric factors, and the risk of pancreatic cancer: Results from the Canadian Enhanced Surveillance System. Int J Cancer. 2001 Oct 1; 94(1):140-7.
Villeneuve PJ, Agnew DA, Johnson KC, Mao Y, and The Canadian Cancer Registries Epidemiology Research Group. Brain cancer and occupational exposure to magnetic fields among males: results from a Canadian population-based case-control. Int J Cancer, 2002; 31:210-217.
Fritschi L, Johnson KC, Kliewer E, Fry R and the Canadian Cancer Registries Epidemiology Research Group. Animal-related occupations and the risk of leukemia, myeloma and non-Hodgkins lymphoma. Cancer Causes Control. 2002 Aug; 13(6):563-71.
Johnson KC. Re: Evaluation of Potential Confounders in Planning a Study of Occupational Magnetic Field Exposure and Female Breast Cancer. Epidemiology. 2002 Sep; 13(5):610-1.
Johnson KC, Pan S, Mao Y and The Canadian Cancer Registries Epidemiology Research Group. Risk factors for male breast cancer in Canada, 1994-97. Eur J Cancer Prev. 2002 Jun; 11(3):253-63.
Johnson KC and Wells AJ. Re: Active and Passive Smoking in Breast Cancer: Prospective Results from the Nurses Health Study. Epidemiology. 2002 Nov; 13(6):745-6.
Hamajima N, Hirose K, Tajima K, Rohan T, Calle EE, Heath CW Jr, Coates RJ, Liff JM, Talamini R, Chantarakul N, Koetsawang S, Rachawat D, Morabia A, Schuman L, Stewart W, Szklo M, Bain C, Schofield F, Siskind V, Band P, Coldman AJ, Gallagher RP, Hislop TG, Yang P, Kolonel LM, Nomura AM, Hu J, Johnson KC, Mao Y, De Sanjose S, Lee N, Marchbanks P, Ory HW, Peterson HB, Wilson HG, Wingo PA, et al. Alcohol, tobacco and breast cancer -- collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer. 2002 Nov 18; 87(11):1234-45.
Villeneuve P, Johnson KC, Hanley AJG, Mao Y and The Canadian Cancer Registries Epidemiology Research Group. Passive smoking and pancreatic cancer risk. 2004 Can J Pub Health 95(1):32-37.
Pan S, Johnson KC, Ugnat AM, Wen SW, Mao Y and The Canadian Cancer Registries Epidemiology Research Group. Association of Obesity and Cancer Risk. 2004. Am J Epid 159(3):259-268.
Do M, Birkett N, Johnson KC, Krewski D, Villeneuve P and CCRERG. Chlorination Disinfection By-products and Pancreatic Cancer Risk. Environmental Health Perspectives, 113(4). April 2005.
Nkondjock A, Ghadirian P, Johnson KC, Krewski D. Dietary Intake of Lycopene Is Associated with Reduced Pancreatic Cancer Risk. J Nutr 2005; 135(3):592-597.
Nkondjock A, Krewski D, Johnson KC, Ghadirian P. Dietary patterns and risk of pancreatic cancer. Int J Cancer 2005; 114(5):817-823.
Kasim K, Levallois P, Abdous B, Auger P, Johnson KC. Environmental tobacco smoke and risk of adult leukemia. Epidemiology 2005; 16(5):672-680
Johnson KC. Accumulating evidence on passive and active smoking and breast cancer risk. Int J Cancer 2005; 117(4):619-628.
Kasim K, Levallois P, Abdous B, Auger P, Johnson KC. Lifestyle factors and the risk of adult leukemia in Canada. Cancer Causes Control 2005; 16(5):489-500.
Repace J, Johnson KC. Can Displacement Ventilation Control Secondhand ETS? ASHRAE IAQ Applications 2006; 7(4):1-6.
Johnson KC. Re: Lissowska J, Brinton LA, Zatonski W, et al. Tobacco smoking, NAT2 acetylation genotype and breast cancer risk. (Int J Cancer 2006; 119:1961-69). More evidence for passive and active smoking and breast cancer risk among younger women. Int J Cancer 2007.
Miller MD, Marty MA, Broadwin R, Johnson KC, Salmon AG, Winder B et al. The association between exposure to environmental tobacco smoke and breast cancer: a review by the California Environmental Protection Agency. Prev Med 2007; 44(2):93-106
Johnson, KC, Glantz S. Evidence that secondhand smoke causes
breast cancer in 2005 stronger than for lung cancer in 1986. Prev Med (epub
ahead of print Dec 2007)
Mina K, Fritschi L, Johnson KC; Canadian Cancer Registries
Epidemiology Research Group. An inverse association between preserved fish and
prostate cancer: results from a population-based case-control study in Canada.
Nutr Cancer. 2008;60(2):222-6.
Collishaw NE (Chair), Boyd NF, Cantor KP, Hammond SK, Johnson KC,
Millar J, Miller AB, Miller M, Palmer JR, Salmon AG, Turcotte F. Canadian Expert
Panel on Tobacco Smoke and Breast Cancer Risk. Toronto, Canada: Ontario Tobacco
Research Unit, OTRU Special Report Series, April 2009.
Kasim K, Levallois P, Abdous B, Auger P and Johnson KC. Recreational
Physical Activity and The Risk of Adult Leukemia in Canada. Cancer Causes and
Control, May 21, 2009.
Bottorff, JL, McKeown, SB, Carey, J, Haines, R, Okoli, C, Johnson,
KC, Easley, J, Ferrence, R, Baillie, L, & Ptolemy, E. (2010). Young
women's responses to smoking and breast cancer risk information. Health Education
Research. DOI: 10.1093/her/cyp067.
Daviss, BA, Johnson, KC, Lalonde A. Evolving Evidence Since
the Term Breech Trial: Canadian Response, European Dissent, and Potential Solutions.
J Obstet Gynaecol 2010;32(3):217-224.
Conlon MSC, Bewick M, Johnson KC, Lafrenie R, Donner A. Smoking
(Active and Passive), N-Acetyltransferase 2, and risk of breast cancer. Cancer
Epidemiology. Cancer Epidemiology 2010;34:142-149.
Johnson KC, Miller AB, Collishaw N, Palmer JR, Hammond SK,
Salmon AG, Cantor KP, Miller MD, Boyd NF, Millar J, Turcotte F. Active Smoking
and Secondhand Smoke Increase Breast Cancer Risk: The Report of the Canadian
Expert Panel on Tobacco Smoke and Breast Cancer Risk (2009). Tobacco Control
(accepted June 10, 2010)
Johnson KC. Environmental Tobacco Smoke and Cancer. Chron
Dis Can, Supplement, 2010. # Johnson KC, Daviss BA. Re:Planned home and hospital
births in South Australia, 1991–2006: differences in outcome. Med J of
Austr. Accepted, planned publication date: June 22, 2010)


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UNIVERSAL CITY, Calif. - March 22, 2012 - NBC has renewed its critically acclaimed musical drama "Smash" (Mondays, 10-11 p.m. ET) for a second season, it was announced today by Robert Greenblatt, Chairman of NBC Entertainment.
"Smash" is NBC's #1 drama in adults 18-49 and total viewers. "Smash" is up 160 percent in 18-49 versus NBC's season average in the time period prior to "Smash" (with a 2.6 rating vs. a 1.0, "live plus same day") and in total viewers, "Smash" has improved the time period by 100 percent (7.7 million vs. 3.9 million).
Among the many positive notices the series has received, USA Today wrote, "'Smash' pulls out all of the entertainment stops and succeeds... just the kind of gloriously entertaining, wildly ambitious network series you hope for each season..." The Los Angeles Times wrote, "...'Smash' is a triumph." And EW.com referred to "Smash" as "...one damn lively show with a lot of promise."
NBC's "Smash" - which debuted February 6 -- celebrates the beauty and heartbreak of the Broadway theater as it follows a cross-section of dreamers and schemers who all have one common desire - to be a "Smash." Evolving from an idea of executive producer and multiple Emmy and Oscar winner Steven Spielberg ("ER," "Schindler's List"), the series unites the hit-making Broadway writing team of Julia Houston (Debra Messing, Emmy winner, "Will & Grace") and Tom Levitt (Christian Borle, "Legally Blonde: The Musical") with producer Eileen Rand (Anjelica Huston, Oscar winner, "Prizzi's Honor") to create a new musical based on the life of Marilyn Monroe, and seasoned chorus girl Ivy Lynn (Megan Hilty, "9 to 5: The Musical") vies with newcomer Karen Cartwright (Katharine McPhee, "American Idol") for the role of a lifetime.
The cast also features Jack Davenport ("Pirates of the Caribbean" films), Raza Jaffrey ("MI-5," "Sex and the City 2"), Brian d'Arcy James ("Shrek the Musical") and Jaime Cepero ("Porgy & Bess"). In addition to Spielberg, the executive producers include Theresa Rebeck ("Mauritius"), David Marshall Grant ("Brothers & Sisters"), Craig Zadan and Neil Meron ("Chicago," "Hairspray"), Darryl Frank and Justin Falvey ("United States of Tara," "The Borgias") and Marc Shaiman and Scott Wittman ("Hairspray," "Catch Me If You Can"). The first three episodes were directed by Tony Award winner Michael Mayer.
"Smash" is a production of Universal Television in association with DreamWorks Television and Madwoman in the Attic.
For embeddable clips and full episodes from "Smash," please visit NBC.com's official show site: http://www.nbc.com/smash/.
Please like us on Facebook at http://www.facebook.com/NBCSmash and follow us on Twitter @NBCSmash.


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Mark Changizi is an evolutionary neurobiologist and director of human cognition at 2AI Labs. He is the author of
The Brain from 25000 Feet, The Vision Revolution, and his newest book, Harnessed: How Language and Music Mimicked Nature and Transformed Ape to Man." What do ironing and hang-gliding have in common? Not much really, except that we weren't designed to do either of them. And that goes for a million other modern-civilization things we regularly do but are not "supposed" to do. We're fish out of water, living in radically unnatural environments and behaving ridiculously for a great ape. So, if one were interested in figuring out which things are fundamentally part of what it is to be human, then those million crazy things we do these days would not be on the list.
But what would be on the list? At the top of the list of things we do that we're supposed to be doing, and that are at the core of what it is to be human rather than some other sort of animal, are language and music. Language is the pinnacle of usefulness, and was key to our domination of the Earth (and the Moon). And music is arguably the pinnacle of the arts. Language and music are fantastically complex, and we're brilliantly capable at absorbing them, and from a young age. That's how we know we're meant to be doing them, i.e., how we know we evolved brains for engaging in language and music. But what if this gets language and music all wrong? What if we're not, in fact, meant to have language and music? What if our endless yapping and music-filled hours each day are deeply unnatural behaviors for our species? (What if the parents in Footloose* were right?!) I believe that language and music are, indeed, not part of our core---that we never evolved by natural selection to engage in them. The reason we have such a head for language and music is not that we evolved for them, but, rather, that language and music evolved—culturally evolved over millennia—for us. Our brains aren't shaped for these pinnacles of humankind. Rather, these pinnacles of humankind are shaped to be good for our brains. But how on Earth can one argue for such a view? If language and music have shaped themselves to be good for non-linguistic and amusical brains, then what would their shapes have to be? They'd have to possess the auditory structure of…nature. That is, we have auditory systems which have evolved to be brilliantly capable at processing the sounds from nature, and language and music would need to mimic those sorts of sounds in order to harness—to "nature-harness," as I call it—our brain. And language and music do nature-harness, a case I make in my third book, Harnessed: How Language and Music Mimicked Nature and Transformed Ape to Man
(Benbella, 2011). The two most important classes of auditory stimuli for humans are (i) events among objects (most commonly solid objects), and (ii) events among humans (i.e., human behavior). And, in my research I have shown that the signature sounds in these two auditory domains drive the sounds we humans use in (i) speech and (ii) music, respectively. For example, the principal source of modulation of pitch in the natural world comes from the Doppler shift, where objects moving toward you have a high pitch and objects moving away have a low pitch; from these pitch modulations a listener can hear an object's direction of movement relative to his or her position. In the book I provide a battery of converging evidence that melody in music has culturally evolved to sound like the (often exaggerations of) Doppler shifts of a person moving in one's midst. Consider first that a mover's pitch will modulate within a fixed range, the top and bottom pitches occurring when the mover is headed, respectively, toward and away from you. Do melodies confine themselves to fixed ranges? They tend to, and tessitura is the musical term to refer to this range. In the book I run through a variety of specific predictions. Here's one. If melody is "trying" to sound like the Doppler shifts of a mover—and thereby convey to the auditory system the trajectory of a fictional mover—then a faster mover will have a greater difference between its top and bottom pitch. Does faster music tend to have a wider tessitura? That is, does music with a faster tempo—more beats, or footsteps, per second—tend to have a wider tessitura? Notice that the performer of faster tempo music would ideally like the tessitura to narrow, not widen! But what we found is that, indeed, music having a greater tempo tends to have a wider tessitura, just what one would expect if the meaning of melody is the direction of a mover in your midst. For the full set of arguments for language and music you'll have to read the book, and the preliminary conclusion of the research is that, human speech sounds like solid objects events, and music sounds like human behavior! That's just what we expect if we were never meant to do language and music. Language and music have the fingerprints of being unnatural (i.e., of not having their origins via natural selection)…and the giveaway is, ironically, that their shapes are natural (i.e., have the structure of natural auditory events). We also find this for another core capability that we know we're not "meant" to do: reading. Writing was invented much too recently for us to have specialized reading mechanisms in the brain (although there are new hints of early writing
as old as 30,000 years), and yet reading has the hallmarks of instinct
. As I have argued in my research and in my second book, The Vision Revolution
, writing slides so well into our brain because it got shaped by cultural evolution to look "like nature," and, specifically, to have the signature contour-combinations found in natural scenes (which consists mostly of opaque objects strewn about). My research suggests that language and music aren't any more part of our biological identity than reading is. Counterintuitively, then, we aren't "supposed" to be speaking and listening to music. They aren't part of our "core" after all. Or, at least, they aren't part of the core of Homo sapiens as the species originally appeared. But, it seems reasonable to insist that, whether or not language and music are part of our natural biological history, they are indeed at the core of what we take to be centrally human now. Being human today is quite a different thing than being the original Homo sapiens. So, what is it to be human? Unlike Homo sapiens, we're grown in a radically different petri dish
. Our habitat is filled with cultural artifacts—the two heavyweights being language and music—designed to harness our brains' ancient capabilities and transform them into new ones. Humans are more than Homo sapiens. Humans are Homo sapiens who have been nature-harnessed into an altogether novel creature, one designed in part via natural selection, but also in part via cultural evolution. * Correction: This bit originally mentionedDirty Dancing instead of Footloose. Thanks to @LaurenAMichael for the 80's pop-culture refresher.An earlier, shorter, version of this piece appeared originally on the Nook.


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(H.Res. 808) The conference report containing the agreement between the House and Senate authorizing fiscal year 2010 funds for the Defense Department - - on a motion to move to an immediate vote on the resolution setting the terms for debating the conference report
house Roll Call 764 Oct 08, 2009
The House and Senate had passed different versions of the bill authorizing fiscal year 2010 funds for the Defense Department and national security programs. When the two Houses of Congress pass different versions of the same bill, a final version is typically negotiated in a conference between a limited number of members of both bodies, and a conference report is developed. That report then must be passed by both Houses before it is sent to the president to be signed into law.
Issue Areas:
To find out how your Members of Congress voted on this bill, use the form on the right.
Find your Member of
Congress' votes


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"Don't just play on your phone, program it," said President Obama in a new promotional video aimed to get students to spend an hour writing computer code.
A non-profit group called code.org enlisted Obama and more than a dozen celebrities—including pop singer Shakira, actor Ashton Kutcher, and NBA star Dwight Howard—to convince kids that it's cool to take a computer science class. Apple stores in Boston and elsewhere offered free coding workshops on Wednesday to promote the effort.
While all this publicity certainly raises awareness about the need to improve computer literacy in the United States, will an hour of coding actually turn high school students into the next Mark Zuckerberg or Bill Gates? Likely not, but it may encourage them to take a programming class in college and have highly in-demand job skills when they graduate.
What's more, kids who learn certain programming skills in elementary or middle school could improve their scores on standardized math tests. Technology educators are just beginning to learn what kinds of programming languages and school curriculums have a beneficial impact with an aim to get more of these classes into public schools nationwide.
In a recent study, Brigham Young University researchers taught Utah middle schoolers basic programming skills in twice weekly afterschool programs and measured a significant increase in math test scores after a few months. "We saw growth in certain math skills like functions and variables used in algebra," said Geoffrey Wright, an associate professor in the technology engineering education program at Brigham Young University who conducted the research.
With such promising results, one public junior high school in Utah has decided to work computer programming into the school day as a part of their state's technology requirement where students also learn basic engineering and software programs such as Adobe Photoshop.
Wright, though, would like to see American schools go further, modeling their curriculums after Great Britain, which will add computer science programming as a core class in 2014 offered along with math, science, and languages in elementary school through high school. "We need to reduce the fear factor of technology and expose kids at young ages, so they grow up with programming and expect to take it yearly," Wright said.
But making that case in individual states which set their own curriculum standards—often based on getting students to perform well on standardized math and language tests—has been tough. About 90 percent of schools in the U.S. don't offer programming classes.
"There's been a long and frustrating history of people trying to prove that programming can teach kids other fundamental skills like problem solving or abstract thinking," said Emmanuel Schanzer, a former coder for Microsoft Corp. and a doctoral candidate in algebra education at Harvard University. "These high expectations have been met with unsatisfying results in research studies."
Schanzer helped develop a curriculum called Bootstrap to teach algebraic and geometric principles by writing code for video games to students ages 12 to 16. Seven schools in Massachusetts and dozens more nationwide have incorporated the 20-hour Bootstrap course into their curriculums often in algebra or pre-algebra math classes taken in eighth or ninth grade.
Like Wright, Schanzer has validated his program by seeing how students perform on math tests conducted before and after taking the programming class and comparing these scores to control groups who take other technology electives.
"It's not enough to just teach kids some programming language and magically expect they'll make the connection to math skills," Schanzer said. "Teachers have to point out explicitly how functions taught in programming will be seen again in their math class." If taught the appropriate computer language with a teacher well-versed in the curriculum, he added, students should be able to use a neurological process called transfer to quickly pick up novel math concepts that overlap with what they learned in programming.
That's actually more complicated than it sounds, since some computer languages could confuse students with programming codes such as "x=x+1" that go against algebraic concepts dictating that "x=x". What's more, high school math teachers often don't have the skills to teach programming.
Bootstrap's programming language—developed by Northeastern computer science professor Matthias Felleisen—provides code consistent with solving mathematical equations, and the curriculum can be obtained for free on the nonprofit organization's website. Schools do, however, have to pay for training workshops for teachers.
Whether programs like Bootstrap work better than other math enrichment programs remains to be seen, Schanzer said. "We have not definitively proven that transfer occurs from learning programming," he added. "We've been working really hard for six years to study this, but we need to conduct research in larger populations of students."
Deborah Kotz can be reached at email@example.com. Follow her on Twitter @debkotz2.


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Putnam County Environmental Health Department
Keeping Your Community Safe
The Putnam County Environmental Health Section provides control and prevention through a combination of surveillance, education, enforcement, and assessment programs designed to identify and abate the environmental conditions that adversely impact human health. Additional information, including Rules and Regulations, can by found for each program at the website of the Division of Public Health Environmental Health Section.
Our Team
Environmental Health County Manager: Kathryn Hill
Hours of Operation
|8 a.m – 4:30 p.m.
|8 a.m – 4:30 p.m
|8 a.m. – 4:30 p.m.
|8 a.m. – 4:30 p.m.
|8 a.m. – 4:30 p.m.
Health department offices are closed on all state-observed holidays.
Contact Us
Call Environmental Health: (706) 485-8591
Send a Fax: (706) 485-2018
Visit or Send Mail:
Putnam County Health Department
117 Putnam Drive, Suite C
P.O. Box 3776
Eatonton, GA 31024
Attend a Board of Health Meeting
We value your thoughts and would love to hear your opinions. All Board of Health meetings are open to the public. Find a schedule of upcoming Board of Health meetings on our Events Calendar.
Food Service Program
The Environmental Health Section permits facilities and conducts quarterly Food Service inspections. The EH Section also provides education, investigates complaints, and assists the Epidemiology Section with Food-borne Illness Investigations. Environmental Health Specialists operate under the auspices of the Georgia Rules and Regulations governing Food Service, Chapter 290-5-14.
- Georgia Rules & Regulations for Food Service
- Food Service Manual– Interpretation Manual
- Food Service Manual– Design, Installation and Construction Manual
- Putnam County Food Services Scores
- Food Educational Materials in Languages Other than the English Language
- What You Need to Know About Food and Water During Power Outages and Floods
Additional Information:
- Supplemental Food Safety & Employee Health Information
- Accredited Certification Programs for Certified Food Safety Managers
- Keeping Foods Safe During an Emergency
- Choking Poster
- Handwashing Poster
- What You Need to Know About Food and Water During Power Outages and Floods
- Guide for Restaurants to Comply with the Americans with Disabilities Act (ADA)
- Food Security – Food Industry Management and Employee Awareness Education
- FDA/ORA Compliance Policy Guides (Food)
- Emergency Guidance for Retail Food Service Establishments
- Boil Water Advisory FAQ: English Version; Spanish Version
Rabies Control
The goal of the Rabies Control Program is to minimize the spread of the rabies virus in the human population. The EH Section conducts investigations and provides technical assistance to private physicians, veterinarians, hospital emergency rooms, and local animal control shelters by following the Rabies Control Law, O.C.G.A. 31-19, and the Department of Human Resources Rules 290-5-2. The EH section coordinates specimen testing with the Georgia Public Health Laboratory. See the Georgia Rabies Control Manual for more information.
Rabies is a viral infection transmitted in the saliva of infected mammals. The virus causes an encephalomyelitis that is almost always fatal in humans. Human rabies is a completely preventable disease if the risk of acquisition is appreciated and appropriate rabies post-exposure prophylaxis (consisting of wound care as well as both active and passive immunization) is obtained. You should reduce your risk of acquiring rabies if you:
- Vaccinate domestic animals as required by regulations
- Avoid contact with stray animals
- Avoid contact with unknown animals
- Avoid contact with injured or sick animals
- Avoid contact with wildlife
All Georgia physicians, laboratories and other health care providers are required by law to report patients with certain notifiable diseases and conditions including animal bites. Animal control, veterinarians, and local law enforcement should also submit animal bite/exposure reports if applicable. Reporting of an animal bite(s) is not restricted to medical personnel and government employees.
It is critical the Health Department receives notification of any animal bite presented in your facility. Rabies is essentially 100% fatal once symptoms are present and the Georgia Rabies Control Law requires that health departments be notified if an animal bite occurs.
Tourist Accommodations
Tourist Accommodations include hotels, motels and campgrounds. The Environmental Health staff inspects Tourist Accommodations at least twice a year to ensure the establishment is providing a clean environment. The inspector will check to make sure linens are cleaned daily, cups and utensils are clean and sanitized and rooms are free of pests.
Additional Information:
Swimming Pools
The Environmental Health staff inspects swimming pools at least twice a year for seasonal pools and three times a year for pools that are open year round. Inspectors make sure that pool chemicals are sufficient to protect swimmers from recreational water illness.
Pool Health and Safety Tips
- Don't swim if you have diarrhea.
- Shower before entering the pool to keep body oils and lotions out of the pool.
- Change diapers in the bathroom and wash children well before entering the pool.
- Children need frequent bathroom breaks to avoid accidents in the pool.
- Wash your hands after using the bathroom or changing diapers.
- Wear sunscreen to prevent sunburns. Reapply often.
- Monitor children while they are in the pool.
Rules and Regulations for Swimming Pools
Public Pool ADA Access Information:
Septic Systems
The most common waste water management system is a septic system. A septic system consists of a septic tank and an absorption field. The tank separates the solids from the liquid. The liquid is dispersed through the absorption field. The water is treated by the soil to remove harmful microorganisms such as bacteria and viruses before it reaches groundwater. The solids left behind in the tank are broken down by bacteria. It is important to have the sludge in the septic tank pumped out on a regular basis, generally every 3-5 years for the average family (2-4 members with a 1000gal tank).
Using your septic system properly will help ensure that it will last for many years. Here are a few tips:
- Conserve water. Wash full loads of laundry and dishes. Don't do all of your laundry in one day. Fix any leaking fixtures.
- Use pipes to direct rainwater from gutters away from your absorption field.
- Use commercial cleansers and anti-bacterial soap in moderation. The cleansers will kill the natural bacteria found in the tank that help break down solid waste.
- Do not plant trees or bushes near or on top of the absorption field. Roots will block the lines causing failure.
- Do not drive across the absorption field or tank. This could cause the lines or tank to be crushed resulting in costly repairs.
- Do not pour grease, oil, paint or chemicals into the system.
- Do not put anything that is not biodegradable into the system. This includes disposable diapers, feminine hygiene products, cigarette butts, etc.
- Chemical additives that are sold to help reduce how often a tank is pumped are not recommended by the Health Department.
Additional Information:
Well Water
Private wells use ground water as its water source. Ground water can become contaminated in many ways. Malfunctioning wastewater treatments (leaking septic systems or sewer overflows), naturally occurring minerals and farming practices can all contribute to well contamination. It is your responsibility to keep your well free from contamination. Contaminated wells can cause serious illness not only for your family, but for other households that use the same aquifer for their water source.
There are steps you can take to protect your well from contamination.
- Maintain your septic system to avoid sewage discharge. Pumping your septic tank on a regular basis (see the GA Department of Public Health website for recommendations), conserve water to avoid overloading the system and use anti-bacterial soap and commercial cleaners in moderation.
- Regularly inspect wells for damage. If your well is damaged call a licensed well driller for repairs.
- Don't discard chemicals near your well.
- Have your well tested annually and regularly disinfect your well.
Before non-public water well can be installed, the homeowner or authorized agent must first apply for a permit with the Environmental Health Department. The application fee and permit includes a site evaluation to determine proper location of the well.
Owner Responsibilities
- It is the owner's responsibility to notify the Environmental Health Department once the well has been installed. At this point an Environmentalist will revisit the property and take a sample from the well and notify the owner of the results.
- All individual and non-public wells shall be curbed at the surface by the owner with watertight curbing of concrete at least four inches thick and extending at least two feet in all directions from the well casing and sloping away from the casing.
- It is recommended that owner's of individual and non-public wells have an annual sample taken for bacterial testing to ensure that the well is a safe source of water.
Driller's Responsibilities
- Driller must be a certified, licensed well driller with the state of Georgia
- Wells must be installed in accordance with State Regulations and all applicable well information (Intents to Drill, Well Data Sheets) must be submitted to the Health Department, Environmental Health Section.
- Follow permit issued by the Environmental Health Department. Make sure well is installed in proper location following state/county mandated setbacks from potential sources of contamination (refer to Georgia Water Well Standards Act).
- After the well has been installed, the driller is responsible for disinfecting the well before any use of the water.
It is recommended that your well water be tested annually for bacteria and a chemical analysis (W-33 analysis) every 3 years. The Environmental Health staff at can test your well for coli form bacteria. Please contact our office at for additional information.
Additional Information:
Additional Resources:


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16DZC genset
Anglo Belgian Corporation manufactures medium-speed engines with various power outputs. These engines, in combination with an alternator, positions ABC to offer powerful power generation solutions. Our engineering department provides complete diesel-electric propulsion solutions and auxiliary gensets to power those ships with the highest technical requirements.
ABC gensets combine all technical advantages of our engines to obtain a reliable source of power for vessels, offshore platforms or any other maritime application. Our 16-cylinder, medium-speed V-engine based on the DZC family offers a perfect balance between performance and required investment. Its simplicity made this engine one of ABC's most wanted engines for marine propulsion and power generation applications across the world.
A high engine displacement, a low brake mean effective pressure (BMEP), a mechanical injection system and an increasing torque curve at decreasing engine speed are just some of the main technical advantages of our 16DZC engines in tugboats, fishing vessels, coasters, dredgers, ferries and other heavy duty applications. The axial-radial turbochargers' response is second to none, allowing the engine to absorb huge shock loads in heavy sea conditions.
The (V)DZC engine offers real value for money. It is characterized by low fuel and lube oil consumption, resulting in an exceptionally low life-cycle cost. Besides Marine Gasoil (MGO) and Marine Diesel Oil (MDO), the 16(V)DZC is able to run on Heavy Fuel Oil (HFO), vegetable oil, ... making it a very flexible, powerful and reliable source of energy. Additionally, the engine is available in dual fuel execution.
The engine can be easily fitted with a selective catalytic reduction (SCR) system for those marine applications requiring IMO Tier III and EPA 4 compliance. In addition, the SCR package can be extended with a diesel particulate filter (DPF), allowing the engine to meet the most stringent emission standards.
All (V)DZC engines can be fitted with modern sensors and operating systems so that they can be controlled with a touchscreen from the bridge but they remain 100 % mechanical, making it easier to maintain and more reliable. We call this "SMART": Simple, Mechanical, Affordable, Reliable and Tailormade according to your requirements.
The 16DZC is user-friendly and delivers outstanding performance under the toughest and most demanding conditions. It has been designed for easy and simple maintenance. Maintaining the required or specified performance was never as easy.
We focus each day on producing quality products that deliver the best performance every hour and every day of the year. Our engineers are at your disposal to offer tailormade propulsion and power generation solutions.
For more information about our products and services, call +32 (0) 9 267 00 00 or fill in our contact form.
Please complete this form to receive an email with a download link.
Thank you
Thank you for your request. Your file has been sent to your e-mail address.


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Having the flu gave me the opportunity to watch U.S. President Barack Obama's inaugural ceremonies on Monday. As I watched, I wondered if I was observing an event that will help foster a new United States of America—an America that is inclusive of all people and enriched by an empowered citizenry.
Obama's speech was a clear expression of his personal beliefs and leadership philosophy and the vision he holds for a more fair and equitable society. It was a call to action—a call to all citizens to be engaged in their future by having a voice in their government. Granted Obama's vision is not a vision shared by all, as transformative visions often are not, since they seek a new way of being and challenge many long held beliefs, assumptions, and norms of behavior. Obama's vision calls us into a new way of being together, as Americans, being in care of one another, and supporting every person in reaching his or her potential. The speech and the inaugural event communicated a call to action to embrace difference and recognize it as a collective strength that can help us find common ground.
I write a lot about the importance of "being in care," especially for leaders and teachers. I see leaders as teachers and teachers as leaders, as both roles are core to creating transformative change. "Being in care" means that we are meaningfully connected to others, always in relationship, and always listening to the needs and acting from a place of what is best for the common or greater good. This is not an easy place to reside, especially for political leaders who find themselves in positions where compromise is often the only path forward. Obama's expression of being in care was powerfully demonstrated at the moment he stopped to savor the meaning of the millions of people who were present for the ceremony. One could tell from his face, that this moment for him, was not one of power, but rather one of the extraordinary meaning of being president of the United States, a position from which he aspires to create transformative changes that improve the lives of those gathered that day and the many others who hope for a better future. One could feel his desire to be connected to those who he has inspired and who continue to inspire him.
There is much need for transformative change in the U.S. and around the world. The challenges of climate change will likely continue to force us to change our way of life, including where and how we live. Strong, resilient communities are needed to face and recover from disasters. I was happy to hear Obama state a strong commitment to addressing the needs of climate change in his second term, as there are many proactive measures we can take to avert the impact of it on our lives. I'm hopeful these shared experiences and collective recovery efforts will serve to change the nature of who we are from a nation of separate individuals who all too often seek self interest to a nation of creative individuals working together to address our collective needs, locally and globally, while preserving and protecting the natural environment.
Transformative change requires us to make the challenges before us central to who we are as Americans. Looking at the faces of pride and hope in the people who gathered for the inauguration, our work is to find ways to come together to define the needs for change and ways to meet them. As Obama so powerfully y stated, "You and I, as citizens, have the power to set this country's course. You and I, as citizens, have the obligation to shape the debates of our time, not only with the votes we cast, but the voices we lift in defense of our most ancient values and enduring ideas."
The next four years are important years to reshape the way we participate as Americans in shaping the society we want our children and grandchildren to inherit. The transformative change President Obama will be able to achieve will be directly related to the actions each of us takes—individually and collectively—as leaders, teachers, parents, social change agents. How can we all engage in this change?
In the words of President Obama, "Let us each of us now embrace with solemn duty and awesome joy, what is our lasting birthright. With common effort and common purpose, with passion and dedication, let us answer the call of history and carry into an uncertain future that precious light of freedom."
Read other posts by Nancy Southern
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What We Say 2001 Alta - Bordeaux Blend
Today we raid Tom Farella's personal stash, to bring you another exclusive wine that you cannot purchase anywhere else
Today's wine is one of the finest red blends that we have ever had the pleasure to enjoy. Do not miss out.
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Mission Codename: New Heights
Operative: Agent Red
Objective: Raid Tom Farella's personal cellar and procure the remaining bottles of his stupendous 2001 Alta, his
Mission Status: Accomplished!
Current Winery: Farella Vineyard
Wine Subject: 2001 Alta
Winemaker: Tom Farella
Backgrounder: Intel reports suggested that Tom Farella was hoarding the remaing supply of 2001 Alta. Further, we learned that the wine was drinking exceptionally well at the moment. Agent Red was instructed to taste the bottle that Tom Farella had given him as a gift earlier this year. Red was under strict instruction infiltrate the winery – if the wine lived up to its reputation. Read Agent Red's tasting notes and mission report below for the full story
Wine Spies Tasting Profile:
Look – Deep burgundy, with a dark and almost black heart, with a fast surface that leaves behind tightly-packed and chubby legs that take forever to emerge before moving slowly down the glass
Smell – Ripe, lush and complex with deep aromatics. Balanced dark fruit of blackberry, blueberry, cassis and cherry intermingles with dark chocolate, black olive, soft dried meats and mildest smoke
Feel – Light and velvet-smooth, this wine glides beautifully across the front of the palate. After a few moments, the wine magically shows off its supple tannins as it coats and leads to a slight dryness
Taste – Gorgeous and delicious with bright fruit of strawberry, cherry and cassis, balanced perfectly against darker flavors of black olive, chocolate, soft smoky oak and soft minerals
Finish – Extremely long, leading off with bright fruit that gradually surrenders to the darker side of the wine as the wines beautiful tannins take hold and add a slight dryness that begs you to take another sip
Conclusion – A stupendous wine that is drinking beautifully – now, and I suspect for years to come. A beautifully balanced wine, with aromas, feel and flavors all peacefully coexisting in perfect harmony, this is a very impressive with that is certain to garner the praise of even the most exacting wine drinker. If you are looking for en elegant wine that is also very approachable, I could not recommend this wine more highly!
Mission Report:
When Tom Farella first gave me a bottle of today's wine, he did so with the disclaimer that I should enjoy it – without the expectation that I could ever show it to our Operatives. And so, I put the bottle into my cellar. There it sat, calling out to me. That is, until H.Q. started receiving chatter about how exceptionally the wine had progressed.
Then, the order came in. I was to open the bottle that I had been saving, in order to evaluate it as a potential Library Raid target. My instructions were simple, "If the wine is great, infiltrate!.
And so it was that I convened a tasting panel. At first sip it was clear that I would be returning to Farella, in order to secure an allocation for our Operatives. The wine was, well, incredible.
Fortunately, all that was required was a call to Tom Farella, who took little convincing that our Operatives would love this wine. Tom agreed to cut away a handful of cases and you, my dear Operative, are the beneficiary of his kind generosity.
Thanks, Tom! We appreciate the allocation of this very special wine!
What follows, for your benefit, is a retransmission of our initial mission report, in which Agent Red first meets Tom Farella:
Earlier this week, I had the great pleasure to visit with Tom Farella, owner and winemaker for Farella Vineyard, at the very south-east corner of Napa Valley.
It is a busy, sometimes hectic time of year for wineries. Winemakers and vineyard managers now find themselves spending hours each day in the vineyards, checking the vines, and watching for that exact moment when the first hints of purple appear on the grapes. That starts a regimented countdown to the fall harvest. Its a somewhat nerve racking time of year – for most winemakers – and Tom is busy preparing and observing.
Tom is a lifer in the wine business. In 1979 he planted the first vineyards that bares his family name. Today, he grows grows cabernet sauvignon, merlot, chardonnay, sauvignon blanc and syrah. Most of the fruit is sold to such high-end Napa wine labels as Lail Vineyards, Honig, Far Niente, Pahlmeyer, Luna Vineyards, Robert Keenan Winery and Realm Cellars. Specific rows of the vineyards are held in reserve for these prestigious wineries and Tom sometimes has his hands full with winemakers as as many as a half-dozen are visiting the grapes on a busy day.
Tom Farella is no ordinary winemaker and do describe his so simply would be to ignore his roles as vineyard manager and adviser to winemakers on a broad range of subjects, from the weather (Tom is a self-described "Weather Geek"), to harvest timing, to crush and wine-making. Tom has been making wine since he graduated from the oenology program at the University of California at Davis, where he received a degree in oenology and viticulture. His career has taken him to France and he has participated in nearly every aspect of the wine trade. Local winemakers and vineyard managers look to Tom for advice. One local that I spoke with referred to Tom as the local "Weather Guru".
Tom's vineyards are situated in the far southeastern corner of Napa Valley, known locally as "Coombsville." The unique soil composition and cooler climate of the region gives wines from here uniquley special characteristics. Tom does not aim for singular differences in his wines. Rather, he shoots for layers of flavors and aromas. Tom also describes his wines as food wines. This is memorialized on the *"Farella with Food" T-Shirts that are available in his tasting room. The wine that we are featuring today, Tom's superb 2004 Cabernet Sauvignon, comes from a combination of Farealla's Old Vine & Rockpile blocks which are positioned on a steep slope facing due west. For the cooler Coombsville area, this gives ideal exposure to the late afternoon sun, a key to slow development of color & tannin in this great wine.
Wine Spies Vineyard Check:
The location of the Farella Vineyards can be seen in this satellite photo.
What the Winery Says
Farella-Park Vineyards
Farella Vineyards, Member, Napa Valley Vintners
About This Wine:
Farella Alta, our Proprietary or "Bordeaux" blend, comes from different parts of our vineyard estate, composed of 70% Cabernet Sauvignon and 30% Merlot. There were only 210 cases produced. It was fermented warm in a combination of open and closed tanks, pressed off after cap fall, with 20 days average on the skins. Transferred directly to Taransaud French oak from the Nevers region after press-off (75% new). Aged 28 months in barrels with 3 rackings. Unfined and unfiltered.
With ripe strawberry, blueberry, and cassis fruit, and a touch of cherry intertwined with dark chocolate, black olive, and smoke. The flavors are full, round and smooth with complex layers, succulent fruit and intense, dark chocolate/black olive backbone to the fine-texture tannins. Smooth and intense yet balanced for service with food.
The Inaugural 2001 Vintage Details:
After 17 vintages of wine from our small winery in the Napa Valley, we have produced a Proprietary or "Bordeaux" blend from different parts of our vineyard estate. This inaugural blend is composed of 70% Cabernet Sauvignon and 30% Merlot.
It literally had taken this long to get this project off the ground. While our Farella-Park Merlot has been blended with some Cabernet all the way back to 1985, this project was different. The vision for this wine literally crystallized in my mind after tasting a 1999 Massetto from Italy, a wine that, ironically enough, is 100% Merlot. There was something about the complex aroma and depth that was very compelling but, moreover, the smooth arc of flavor and structure really caught my attention. I knew we had components in the cellar from newer and old blocks in the vineyard that could marry in a similar fashion and so the blending quest began. I knew I nailed it when my dad, our noble founder and toughest customer, simply remarked "Hmm, I like that."
The lots selected for the blend comprised a large portion of our Old Vine Cabernet which has been the foundation of our varietal Cabernet since 1991. Added to that, is some of the Rockpile block which was planted in 1994 and represents the first wave of replanted Cabernet post-phylloxera. The Merlot is also a combination of two blocks, one being Orchard Block which lives on with its AxR roots (NON-phylloxera –resistant, to those who know or care) and a bigger portion of the Divide Block on the volcanic ashy soils near the road, most of which goes to Pahlmeyer.
About The Winery, Winemaker and Vineyards:
This year marks the 27th vintage for me as a vintner, something my father, Frank Farella, encouraged me to do as a boy while blazing a trail along the way. When I was 12 years old, our family visited the Burgundy region in France which illuminated winemaking as a beautiful mixture of science, farming, craft, creativity and old-fashioned hard, physical work. It doesn't hurt that most fine wine regions of the world are also in beautiful places.
My father's long-sought goal to grow wine grapes from a modest, depression-era background was a story that unfolded slowly and steadily for us. In the mid 70's, it was actually affordable to buy land here but the process of establishing a 26 acre vineyard was far less clear-cut. Most of us in the wine business learned together, piece by piece, in a time when the Napa Valley had a lot of potential but not much credibility. Now, in the new millennium, we find ourselves literally leading the way in a vast, complex industry that seems to always start from lofty dreams and hard work much like my father's story.
The path for me led to UC Davis, Neyers and Flora Springs in Napa, Preston in Sonoma, Prieur in Meursault, Ponzi and Beaux Freres (vineyard) in Oregon and finally back to our home vineyard a few miles from downtown Napa. We relish our role as growers for other prestigious wineries while keeping just a few favorite blocks for ourselves. Our practices are steeped in quality and experience with a solid dose of maintaining a healthy, natural environment. We are blessed with a location against the Vaca Mountains that is abundant in wildlife and has a perfect sunset seemingly every day.
As I grow older, fewer places seem to match the raw beauty of the Napa Valley and I never grow weary of the work. It really is a fascinating thing to take a plant, stick it in the ground, grow some luscious fruit, ferment it naturally, age it in an oak barrel, draw off the clear wine and put it in a bottle. In 5, 10, 20, 30 years you may find out what that little plant in that place is really all about. This magic is what we offer from our little slice of a very unique spot in a special valley on the planet.
Our winemaking philosophy starts with a balanced vineyard and finishes with balanced wines with an eye toward service with food, the perfect compliment – and vice-versa. These are wines that reflect the location, something innate to the land and shaped by our philosophy. We offer something unique and very personal all bottled up, sealed with a cork, nice and neat. We encourage you to visit and taste and see for yourselves.
Technical Analysis:
Varietals: Cabernet Sauvignon 70%, Merlot 30%
Cases produced: 300, 10 cases magnums
Winemaking: Fermented warm in a combination of open and closed tanks, pressed off after cap fall, 20 days average on the skins. Transferred directly to Taransaud French oak from the Nevers region after press-off, 75% new. Aged 28 months in barrels with 3 rackings.
Processing: Unfined and unfiltered.
pH: 3.75 p
Alcohol: 13.9%
Release Date: May 2006


text:
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text:
Egyptian Ideas of the Future Life
By Sir Wallis Budge
THE following pages are intended to place before the reader in a handy form an account of the principal ideas and beliefs held by the ancient Egyptians concerning the resurrection and the future life, which is derived wholly from native religious works. The literature of Egypt which deals with these subjects is large and, as was to be expected, the product of different periods which, taken together, cover several thousands of years; and it is exceedingly difficult at times to reconcile the statements and beliefs of a writer of one period with those of a writer of another. Up to the present no systematic account of the doctrine of the resurrection and of the future life has been discovered, and there is no reason for hoping that such a thing will ever be found, for the Egyptians do not appear to have thought that it was necessary to write a work of the kind. The inherent difficulty of the subject, and the natural impossibility that different men living in different places and at different times should think alike on matters which must, after all, belong always to the region of faith, render it more than probable that no college of priests, however powerful, was able to formulate a system of beliefs which would be received throughout Egypt by the clergy and the laity alike, and would. be copied by the scribes as a final and authoritative work on Egyptian eschatology. Besides this, the genius and structure of the Egyptian language are such as to preclude the possibility of composing in it works of a philosophical or metaphysical character in the true sense of the words. In spite of these difficulties, however, it is possible to collect a great deal of important information on the subject from the funereal and religious works which have come down to us, especially concerning the great central idea of immortality, which existed unchanged for thousands of years, and formed the pivot upon which the religious and social life of the ancient Egyptians actually turned. From the beginning to the end of his life the Egyptian's chief thought was of the life beyond the grave, and the hewing of his tomb in the rock, and the providing of its furniture, every detail of which was prescribed by the custom of the country, absorbed the best thoughts of his mind and a large share of his worldly goods, and kept him ever mindful of the time when his mummified body, would be borne to his "everlasting house" in the limestone plateau or bill.
The chief source of our information concerning the doctrine of the resurrection and of the future life as held by the Egyptians is, of course, the great collection of religious texts generally known by the name of "Book of the Dead." The various recensions of these wonderful compositions cover a period of more than five thousand years, and they reflect faithfully not only the sublime beliefs, and the high ideals, and the noble aspirations of the educated Egyptians, but also the various superstitions and childish reverence for amulets, and magical rites, and charms, which they probably inherited from their pre-dynastic ancestors, and regarded as essentials for their salvation. It must be distinctly understood that many passages and allusions in the Book of the Dead still remain obscure, and that in some places any translator will be at a difficulty in attempting to render certain important words into any modern European language. But it is absurd to talk of almost the whole text of the Book of the Dead as being utterly corrupt, for royal personages, and priests, and scribes, to say nothing of the ordinary educated folk, would not have caused costly copies of a very lengthy work to be multiplied, and illustrated by artists possessing the highest skill, unless it had some meaning to them, and was necessary for the attainment by them of the life which is beyond the grave. The "finds" of recent years in Egypt have resulted in the recovery of valuable texts whereby numerous difficulties have been cleared away; and we must hope that the faults made in translating to-day may be corrected by the discoveries of to-morrow. In spite of all difficulties, both textual and grammatical, sufficient is now known of the Egyptian religion to prove, with certainty, that the Egyptians possessed, some six thousand years ago, a religion and a system of morality which, when stripped of all corrupt accretions, stand second to none among those which have been developed by the greatest nations of the world.
August 21st, 1899.
Content (Revised)
|CHAPTER I. The Belief in God Almighty
|CHAPTER II. Osiris the God of the Resurrection
|CHAPTER III. The "Gods" of the Egyptians
|CHAPTER IV. The Judgment of the Dead
|CHAPTER V. The Resurrection and Immortality


text:
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text:
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response. Whereas an agonist causes an action, an antagonist blocks the action of the agonist, and an inverse agonist causes an action opposite to that of the agonist.
From the Greek αγωνιστής (agōnistēs), contestant; champion; rival < αγων (agōn), contest, combat; exertion, struggle < αγω (agō), I lead, lead towards, conduct; drive
Types of agonists
Receptors can be activated by either endogenous agonists (such as hormones and neurotransmitters) or exogenous agonists (such as drugs), resulting in a biological response. A physiological agonist is a substance that creates the same bodily responses but does not bind to the same receptor.
- An endogenous agonist for a particular receptor is a compound naturally produced by the body that binds to and activates that receptor. For example, the endogenous agonist for serotonin receptors is serotonin, and the endogenous agonist for dopamine receptors is dopamine.[1]
- Full agonists bind to and activate a receptor with the maximum response that an agonist can elicit at the receptor. One example of a drug that can act as a full agonist is isoproterenol, which mimics the action of adrenaline at β adrenoreceptors. Another example is morphine, which mimics the actions of endorphins at μ-opioid receptors throughout the central nervous system. However, a drug can act as a full agonist in some tissues and as a partial agonist in other tissues, depending upon the relative numbers of receptors and differences in receptor coupling.
- A co-agonist works with other co-agonists to produce the desired effect together. NMDA receptor activation requires the binding of both glutamate, glycine and D-serine co-agonists. Calcium can also act as a co-agonist at the IP3 receptor.
- A selective agonist is selective for a specific type of receptor. E.g. buspirone is a selective agonist for serotonin 5-HT1A.
- Partial agonists (such as buspirone, aripiprazole, buprenorphine, or norclozapine) also bind and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist, even at maximal receptor occupancy. Agents like buprenorphine are used to treat opiate dependence for this reason, as they produce milder effects on the opioid receptor with lower dependence and abuse potential.
- An inverse agonist is an agent that binds to the same receptor binding-site as an agonist for that receptor and inhibits the constitutive activity of the receptor. Inverse agonists exert the opposite pharmacological effect of a receptor agonist, not merely an absence of the agonist effect as seen with an antagonist. An example is the cannabinoid inverse agonist rimonabant.
- A superagonist is a term used by some to identify a compound that is capable of producing a greater response than the endogenous agonist for the target receptor. It might be argued that the endogenous agonist is simply a partial agonist in that tissue.
- An irreversible agonist is a type of agonist that binds permanently to a receptor through the formation of covalent bonds. A few of these have been described.[2][3]
New findings that broaden the conventional definition of pharmacology demonstrate that ligands can concurrently behave as agonist and antagonists at the same receptor, depending on effector pathways or tissue type. Terms that describe this phenomenon are "functional selectivity", "protean agonism",[4][5][6] or selective receptor modulators.[7]
Potency is the amount of agonist needed to elicit a desired response. The potency of an agonist is inversely related to its EC50 value. The EC50 can be measured for a given agonist by determining the concentration of agonist needed to elicit half of the maximum biological response of the agonist. The EC50 value is useful for comparing the potency of drugs with similar efficacies producing physiologically similar effects. The smaller the EC50 value, the greater the potency of the agonist, the lower the concentration of drug that is required to elicit the maximum biological response.
Therapeutic index
When a drug is used therapeutically, it is important to understand the margin of safety that exists between the dose needed for the desired effect and the dose that produces unwanted and possibly dangerous side-effects (measured by the TD50, the dose that produces toxicity in 50% of individuals). This relationship, termed the therapeutic index, is defined as the ratio TD50:ED50. In general, the narrower this margin, the more likely it is that the drug will produce unwanted effects. The therapeutic index emphasizes the importance of the margin of safety, as distinct from the potency, in determining the usefulness of a drug.
See also
- Goodman and Gilman's Manual of Pharmacology and Therapeutics. (11th edition, 2008). p14. ISBN 0-07-144343-6
- De Mey JGR, Compeer MG, Meens MJ (2009). "Endothelin-1, an Endogenous Irreversible Agonist in Search of an Allosteric Inhibitor". Mol Cell Pharmacol. 1 (5): 246–257.
- Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK (January 2013). "Structure and function of an irreversible agonist-β(2) adrenoceptor complex". Nature. 469 (7329): 236–40. doi:10.1038/nature09665. PMC 3074335. PMID 21228876.
- Kenakin T (March 2001). "Inverse, protean, and ligand-selective agonism: matters of receptor conformation". FASEB J. 15 (3): 598–611. CiteSeerX 10.1.1.334.8525. doi:10.1096/fj.00-0438rev. PMID 11259378.
- Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, et al. (January 2007). "Functional selectivity and classical concepts of quantitative pharmacology". J. Pharmacol. Exp. Ther. 320 (1): 1–13. doi:10.1124/jpet.106.104463. PMID 16803859.
- De Min, Anna; Matera, Carlo; Bock, Andreas; Holze, Janine; Kloeckner, Jessica; Muth, Mathias; Traenkle, Christian; De Amici, Marco; Kenakin, Terry (2017-02-24). "A New Molecular Mechanism To Engineer Protean Agonism at a G Protein–Coupled Receptor". Molecular Pharmacology. 91 (4): 348–356. doi:10.1124/mol.116.107276. PMID 28167741.
- Smith CL, O'Malley BW (February 2004). "Coregulator function: a key to understanding tissue specificity of selective receptor modulators". Endocr. Rev. 25 (1): 45–71. doi:10.1210/er.2003-0023. PMID 14769827.