text:
I stared at Steven's message, my mouth suddenly dry, and my erection straining against my boxers.
'Yes, I do. And you want to fuck me too. I saw it in your eyes,' he responded moments later.
I blinked, shocked and turned on by his frankness and courage. I decided to take a leaf from his book.
'You're right. I do want to fuck you, but sadly you are in a relationship with someone I care about a lot. It won't be right.'
'You won't mind fucking him again, right?' Steve replied.
'What?!' This guy was actually mad sha.
'Lol. Calm down. Chibuzor also still wants to fuck you. I don't blame him, since I've finally met you and now I want to do naughty things to you as well.'
'Oh wow,' I replied.
'Lol. Ikr?'
'What exactly is going on here?' I asked him. I hoped this wasn't some sort of trap or mind game or whatever.
'Well, I'm trying to propose a threesome between you, myself and my boyfriend. I'm not doing a very good job, am I?'
A threesome? My earlier vision of Chibuzor and Steven tangled in silk sheets adjusted slightly in my mind's eye, and I saw myself in the mix, my legs tangled with Steven's long lean golden ones, my fingers splayed across Chibuzor's wide chest. Oh my God, it would be so amazingly hot.
'Wait, is this a trap? Forgive me for asking, but I don't really know you that well,' I asked.
'I understand. It's not a trap. Just ask Chibuzor. It was actually his idea, that's why I wanted to meet you first. He'd have asked you himself but he's such a shy pansy sometimes. It's cute.'
'Lol! I see…' I responded.
I quickly left the chat and opened one with Chibuzor.
'Is it true that you want to have a threesome with me and your boyfriend?'
'Yes,' he responded with a covered-face smiley. 'Please don't be offended.'
'Why would I be?' I asked, slightly amused.
'You seem very prim and proper, and I know you haven't had a threesome before. I didn't know how you'll react.'
'You'll be surprised.'
'Is that a yes?' he asked with a fingers-crossed emoticon.
I bit my lip as I stared at my phone screen. Was that really a yes? Was I going to have sex with two men at the same time? My fingers hovered over the N button. New experiences were scary and I didn't like unknown quantities. Besides, I had exams I was preparing for. I didn't need any distractions.
But then again, we only live once right?
My fingers pressed against my straining erection through my fly as I watched Chibuzor and his boyfriend kiss on the couch in Chibuzor's apartment. Chibuzor moaned in pleasure as Steven's fingers locked behind his head and pressed him deeper into the kiss. He grabbed Steve's lean firm butt and pressed him against his crotch and Steve actually purred.
I licked my lips, touching myself, waiting for my chance to participate, since these two seemed so into each other. I was beginning to wonder why I was invited.
Soon enough, they came up for air, looking deeply into each other's eyes, and I slid deftly in between them, turning Steven's lips to face mine and capturing the pink twins in a kiss. His lips tasted like magic and they were soft and supple. When I felt his tongue touch my bottom lip, I gasped in pleasure and surprise. He wasted no time in inserting his tongue into my mouth, using it to caress the roof of my mouth while I made helpless moaning sounds of pleasure.
Chibuzor suddenly pulled at me and turned me to face him.
"My turn…" he growled, grabbing my face and bringing it towards his own, kissing me aggressively.
I responded in kind, my lips devouring his, as I shoved off his shirt, and allowed myself feel his thick hard muscled body. I felt fingers around the waistband of my jeans, and before I could reason, they were off, together with my underwear, tangled around my knees. I broke out of the kiss and turned to find Steve on his knees, grinning at me, his hands grabbing at my ass.
"Shhh, pretend I'm not here," he said, his hands parting my butt cheeks and one finger already stroking my entrance.
Pretend he wasn't here, he says. What a clown.
Chibuzor turned me back to face him and we resumed kissing. I bit his bottom lip gently and he gasped in pleasure. I ran my tongue around his oral interior, and then proceeded to lick his lips all over, before pushing his head back and feasting my lips on his neck.
I grinned inwardly as I felt the tremors of pleasure run through his powerful body, but then Steve's deft tongue stroking my asshole brought a startled "Ooh!" from my mouth.
Steve stroked and licked and lapped me up with his tongue, like my ass was made out of premium chocolate. My waist twisted in pleasure and as if that wasn't enough, he inserted one finger into my hole as he licked away. I moaned and began to thrust against his finger. Before I knew it, Chibuzor who was now naked had engulfed my penis in his warm mouth. It was all just so much; it was a struggle not to climax right there.
I pushed Chibuzor away and turned to face Steven who was also suddenly completely naked, and I let my hungry eyes roam over his lean hard golden physique. He caught me staring and grinned cockily at me. I decided to wipe that smirk from his face. I dropped to my knees and inserted his long yellow penis deeply into my mouth, and he actually cried out. I sucked him and brought him back out a few times, running my deft tongue over the throbbing head, licking his balls. He trembled at my ministrations. Chibuzor decided to take me by surprise by sticking his tongue into my asshole, sending shock waves of pleasure all over my body. Soon enough, after what seemed like an endless vortex of pleasure, Chibuzor slapped on a condom and slid himself into me. I almost screamed, but Steve's penis in my mouth prevented me. He thrust into me a few times and eventually came. He pulled out and Steve took his place, riding me like a cowboy riding a mustang. Chibuzor slid over to my front and began kissing me, his fingers slipping up and down over my dick, while I thrust my ass back with each thrust of Steve's pelvis, the maximum pleasure threatening to consume me.
Several moments later, Steve splayed himself on the bed, and looked up at me like I was prime steak. He flung back his long legs, and I saw his sweet looking asshole. I couldn't resist. I knelt down on the bed and ate him out just as good as he did me, and I smiled in satisfaction when I spied the uncontrollable pleasure on his face. I slapped on a condom and thrust into him, his warmth threatening to push me over the edge. I rammed into him and he made squealing sounds of pleasure, sounds that became muffled when Chibuzor came over and thrust his thick penis in his mouth. It was all just too much, and I came aggressively, slumping on the bed behind Steve.
Chibuzor rolled over to me and hugged me, kissing my forehead gently. I motioned to his boyfriend who was staring at us, his erection still pulsing. Chibuzor and I exchanged evil looks. We had to finish Steve off.
I swallowed Steven's penis and Chibuzor ate him out properly. The poor boy could do nothing much except writhe and cry out in pleasure at our ministrations. Soon enough, he came. He came loudly, with gasping screams that Chibuzor had to silence with a hard kiss.
A few minutes later, as we lay sated in bed, leisurely stroking each other's damp bodies, I thought to myself how amazing these two guys were. They had better never invite me over again for a ménage à trois, because I just might get addicted. I giggled to myself, and Steven and Chibuzor both gave me inquiring looks. I winked back at them and closed my eyes, slowly drifting off into sated slumber.
Written by Santa Diaba
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44 Comments
Just like Andrevn suggested last night.??? I'm really interested in hearing how this relationship between Steve and Chibuzo plays out. Is the relationship for real? Are they officially an open couple? Will Steve be okay with chibuzor regularly banging Santa on the side.
Just turn am into series biko.
Ok I'm abit sheepish to admit this but this was too hot, Goodness . I particularly loved the 'indiscriminate rimming'
Where is a penis or anything penile shapped when you need one?
Nice nice.
Santa Diaba wow that was impressive, i'm confused here is this fiction or nonfiction?.
Lmao. My dear that thought has most definitely crossed my mind bet in this life things dey happen.
stranger things have happened. actually, anyone in the gay community knows this is not that much of a big deal
o oooh u dont say!!!!
Looool. Err, well, it's actually non-fiction. VERY non-fiction. ???????
OMG…. *fans red face*
As if the cold morning isnt bad enough…I am as hard as a rock . Pink panther &Santa… God is watching you in 3D.
That sex though ?? ?
Getting a hard-on at work… my mistake.
*eyeing Curves one kain*
Cat fight, cat fight. Round 1. ??
Lol Fancis ur so bad.
I refuse 2 be turned on by fiction! Buh den again, Santa ws so good wif his story…I hd 2 let myself…oops!
*covering ma eyes*
Three of you are hoes. Tufia
I wonder when its gonna turn into a foursome..
I wish you guys the best of luck.
Lmaooooo. It's a one off abeg. You know what they say about "try everything once" right?
Dude, ain't nothing wrong with 3 or more somes if handled properly??
I have a feeling this isn't the last time.
Oh my oh my oh my……holy maxine. ….are you indirectly requesting to join the mix…….to make it foursome….. steve – chibuzor – santa – max………….
Yup!! I suggested it yesterday…A 3some!!???
Dearest Pinky. Thanks for posting! I always blush/shake head for myself whenever I remember this.
Ps, Chibuzor and Steve are still together. They're really amazing guys, and NO, I won't be engaging in any threesomes with them in the nearest foreseeable future. ??
Thanks for the update. ?
For someone that gets this all the time.. This was quite spot on the discription and its so addictive, regular sex with one person gets boring.
My advice
DO NOT explore this sexual tryst.. Once you strt there is no going back. And the hunger for more bodies on the spread sheet gets bigger.
Lastly if you are bottom and you want to engage in a threesome, make sure its two tops. If you invite another bottom esp when the top is your boo, trust me! The party would be ruined. (This second advise does not apply to Max and his other Vasatile folks)
warris dis one saying sef ochim
Nice, dirty, raunchy piece!!! loved it!! am a bit squeamish as well as a prude, so i dont know if i'll be able to relax enough to enjoy a 3-some; but i fantasize about it all the time …
***Mops brows*** Phew! ???????
Hmmn! Bia Pinky, I actually thought yellow ppl abi is it fair they call them have dark penis, true? ???????????
U don spoil
kryxxx LMAO..
This is one of the best (if not the best sex story) have read here ……the intrigue and suspense from the previous parts…..got me going already. …..but this part killed it completely. ….mehn…..damn!!! …..
It's bad I entered into a new relationship less than 12 hours ago. ….I would've sent in my cv…..but again. ….u can never say never…….
I think I Love these kind of Relation,Cause Outdoor. Services is allowed.
Now they're finally speaking up.. Finally
Bia Kedu ihe ina Ako, In mercy Johnson's Voice
The way my erection is fighting to get out of my pants though. I just read the 3rd part in a friends room and I'm like, why didn't I wait until I get home and run to the bathroom. My main concern is how will Steven and Chibuzor continue with their relationship? They both just fucked Chibuzor's ex. This was a great read.
Am new here! What a nice way of welcoming me.
Enough exchange of bacteria, with that kind of kissing and rimming
I've always hd a thing 4 group-sex…it hs always turned me on. But den again, I dnt fink I hv d liver 2 ever engage in any as I am more of d 'romantic' type…nd no group sex hs dat.
Group sex with versatiles on d oda hand (like d story depicted) isn't so appealing anyway…so I wish dere's a way d writer cn just turn dia orientation around…cnt d protagonist be a strict bottom? *just saying*
I have had threesomes a few times. The last one was with two verse guys. I straffed both of them and they both straffed each other too ! Shit was too hot. Unfortunately, we couldn't repeat it again as one of them is deceased now and Nigerian guys are mostly close minded when it comes to sex. You hardly see someone here who is comfortable to have a threesome with you.


text:
ST. PATRICK'S DAY GIFT: Kohler "Emeralds"
Mint, one of the four flavors of Emeralds.
Photo courtesy Kohler.
Some people would like a bottle of Irish whiskey for St. Patrick's Day.
Others would rather have chocolate. And there's one box of chocolates that's perfect for St. Patrick's Day.
Inspired by the Emerald Isle, Kohler's Emerald chocolates are a beautiful box of chocolates with "green"-flavored ganaches*, enveloped in milk chocolate.
All of the chocolates are emerald-shaped shells in milk or semisweet chocolate, painted† in different shades of green.
Each flavor—Absinthe, Green Tea, Lime and Mint—has a different design.
*Ganache is a velvety smooth blend of chocolate and cream, often with butter added, that is rolled in cocoa powder and sugar or other coatings to make a truffle. It is also used as a center for bonbons. Ganache can be made from dark, milk, or white chocolate and flavored with chocolate, coffee, liqueurs, extracts—virtually any flavor that inspires the chocolatier. More about ganache, and why it means "imbecile" in French.
†The "paint" is colored cocoa butter.
Boxes are available in 4, 9 and 32 pieces: $9.99, $18.99 and $59.99. Get yours at KohlerChocolates.com.
Kohler, known for fine porcelain fixtures and The American Club resort in Kohler, Wisconsin, was seriously considering purchasing a chocolate company to provide guests with fine confections. But CEO & Chairman, Herbert V. Kohler, Jr., loved chocolate caramel turtles, and couldn't find a company that made the perfect turtle.
So he challenged the chefs at his resort to create a better turtle. After much testing, a recipe emerged that met Mr. Kohler's standards for flavor, texture and appearance. This morsel evolved into the signature Terrapins that launched Kohler Original Recipe Chocolates in 2007.
A figure shrouded in myth, the man who became the Apostle of Ireland was born in England, around 385 C.E. to a prominent Christian family. He was captured by pirates at age 16, brought to Ireland and sold into slavery.
The green tea-flavored Emerald. Photo courtesy Kohler.
His master, Milchu, was a high priest of Druidism, a Pagan sect that ruled religious influence over Ireland at the time. The enslaved young man worked as a shepherd, and during that time was called to Christianity.
He escaped after six years, returned to his family and entered the priesthood, returning to Ireland as a missionary. As he converted Druids to Christianity, his teachings combined Irish pagan beliefs with Christian sacrament; he is credited with devising the Celtic Cross.
After a lifetime spent converting of Ireland to Christianity—founding monasteries, organizing Ireland into dioceses and so forth—Patrick died circa 461.
His birthday is not known, but St. Patrick's Day is celebrated on March 17th, which falls during the Christian season of Lent. A religious holiday in Ireland, it has been celebrated for more than 1,000 years with a church service in the morning and a traditional dinner cabbage and Irish bacon.
Corned beef is actually an American contribution to the holiday. Immigrant Irish learned how to make corned beef from their immigrant Jewish neighbors.

subset: commoncrawl


text:
Concert Pharmaceuticals, Inc. (CNCE)
Q3 2019 Earnings Call
Nov 8, 2019, 4:30 p.m. ET
- Prepared Remarks
- Questions and Answers
- Call Participants
Prepared Remarks:
Good morning, ladies and gentlemen. Thank you for standing by, and welcome to the Third Quarter Update Call. [Operator Instructions] As a reminder, this conference call may be recorded.
I would now like to turn the conference over to Ms. Justine Koenigsberg, Senior Vice President of Corporate Communications and Investor Relations. Ma'am, please go ahead.
Justine E. Koenigsberg -- Senior Vice President, Corporate Communications and Investor Relations
Thank you. Good morning, and welcome to Concert Pharmaceuticals' Third Quarter 2019 Investor Update. Joining me this morning with prepared remarks are Roger Tung, our President and CEO, Jim Cassella, our Chief Development Officer, and Marc Becker, our CFO. We will also be joined by Nancy Stuart, our Chief Operating Officer, for the Q&A portion of the call.
As a reminder, today's discussion will include forward-looking statements about our future expectations, plans and prospects. These statements are subject to risks and uncertainties that may cause actual results to differ materially from those projected. A description of these risk factors can also be found in our most recent 10-Q filed with the SEC. Any forward-looking statements speak only as of today's date, and we assume no obligation to update any forward-looking statements made on today's call.
With that, I would now like to turn the call over to Roger.
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
Thank you, Justin, and good morning.
In 2019, we have accomplished important progress in our pipeline, with strong results generated with both our proprietary candidates, CTP-543 for moderate-to-severe alopecia areata and CTP-692 for adjunctive treatment of schizophrenia.
We've been actively presenting both of these clinical programs at scientific and medical meetings this year and we're very pleased with the enthusiasm shown for both candidates results and their potential to address an important unmet needs for chronic diseases.
For CTP-543, we believe the Phase 2 results have set a new benchmark for clinical efficacy in the treatment of alopecia areata. In a moment, Jim will recap the results presented at EADV last month. With our Phase 2 results, we've identified two doses of CTP-543 with promising efficacy and tolerability profiles, both of which may be suitable for assessment in future trials. We also see some advantages of the higher dose, including faster onset and greater magnitude of effects. The program is progressing nicely, and we expect to advance CTP-543 into Phase 3 testing in 2020.
As a reminder, we are also conducting two-dose regimen studies, evaluating twice-daily versus once-daily dosing. Both of these studies are fully enrolled, increasing our patient database and helping us to define the characteristics of these doses and dose regimens of CTP-543. These data will be very helpful as we meet with FDA in an end of Phase 2 meeting next year.
As a reminder, we filed a notice of appeal with Federal Circuit Court challenging the PTAB's decision on the patentability of our CTP-543 composition-of-matter patents. In addition, we are actively pursuing other IP protection for CTP-543, including a pending application that's supported by an impressive Phase 2 results and several more applications in preparation. We hope to have more to say on this topic in 2020.
Now turning to CTP-692, our drug candidate that is a deuterated form of D-serine. We're excited about the prospect of CTP-692 because it offers patients a scientifically well-supported potentially, a new mechanism of action to treat schizophrenia, which is a disease that continues to have substantial unmet medical need. The activity of D-serine in schizophrenia is supported by positive clinical results with non-deuterated D-serine, which, however, is limited by renal toxicity concerns. We will move our CTP-692 into Phase 2 later this year with confidence that 692 has the potential for a much safer product profile than that of non-deuterated D-serine.
In addition to our proprietary drug candidates, Avanir reported in September, top line results from the second Phase 3 trial for AVP-786, which is a compound Concert licensed to Avanir back in 2012. While we were disappointed that the trial did not meet its primary and secondary -- key secondary endpoints, it's important to note that under the structure of our license agreement, all development costs and activities for AVP-786 were the responsibility of Avanir. Avanir and its parent, Otsuka, have stated that they will analyze the full set of data from the first two studies and explore the best path forward. I will note that our agreement with Avanir is not specific to indication, and there are a number of ongoing trials evaluating AVP-786 in multiple neuropsychiatric indications.
Let me conclude by emphasizing our optimism for Concert's pipeline. With the strong data we've developed this year with our proprietary compounds, we have multiple possibilities to create significant near-term and long-term value for Concert.
I'd like to pause here and ask Jim to discuss our clinical progress, and then Mark will review our third quarter financial results before we open the call to questions.
James V. Cassella -- Chief Development Officer
Thank you, Roger. We've made excellent progress on the clinical development front across both our proprietary programs this year, and we are well-positioned to continue advancing CTP-543 for alopecia areata and CTP-692 for schizophrenia into their next phases of development.
Beginning with CTP-543. We were delighted to have had the opportunity to present our Phase 2 data during the late-breaking news session at the EADV Congress last month. The meeting provided a great platform to showcase our program to the international medical dermatology community and clinicians, who specialize in treating alopecia areata in both Europe and the US.
Let me briefly review the top line results from the Phase 2 dose-ranging trial with CTP-543. As a reminder, the primary endpoint analysis in the Phase 2 trial compares the proportion of responders between placebo and each of the active CTP-543 dose groups at week 24. A responder is defined as a patient achieving at least a 50% relative reduction in SALT score compared to their baseline.
The Phase 2 results demonstrated very clear dose-related response, and the primary endpoint was met with statistical significance for both the 8-milligram twice-daily and 12-milligram twice-daily doses. For ease of discussion, I will refer to the 8-milligram twice-daily and 12-milligram twice-daily dose groups as the 8-milligram and 12-milligram cohorts, respectively.
58% of patients in the 12-milligram cohort and 47% of patients in the 8-milligram cohort were responders at week 24. The 8-milligram and 12-milligram cohorts, each showed significant improvement from the 9% placebo response. The 4-milligram twice-daily cohort had a 21% response rate, which was not statistically significant from placebo and will not be a dose carryforward into later-stage development.
Let me also note that further improvement was observed with the 12-milligram cohort at response levels beyond the 50% improvement in SALT. The 12-milligram cohort was significantly different from placebo, with 42% of the group achieving at least a 75% improvement in SALT and 36% achieving at least a 90% SALT change.
For the 90% threshold, we see not only a statistical separation for the 12-milligram dose group from placebo starting at week 20, but we also find a significant separation from the 8-milligram dose cohort. So with this higher response threshold, the 12-milligram dose appears to provide an additional benefit over the 8-milligram dose.
In addition to hair loss analysis using SALT, we also asked patients to rate their sense of improvement in their alopecia reata after 24 weeks of dosing as a secondary endpoint. Data from the Patient Global Impression of Improvement Scale show a very favorable dose-related response curve, with nearly 80% of patients receiving 12-milligram, saying that their alopecia was either much improved or very much improved compared to when they entered the study.
CTP-543 was generally well-tolerated in the Phase 2 trial. The percent of patients experiencing adverse events was similar between the 8-milligram and 12-milligram cohorts and the placebo group. The most common adverse events reported across the treatment groups were headache, nasopharyngitis or common cold, upper respiratory tract infection and acne. One serious adverse event was reported for patient in 12-milligram cohort, who was treated for cellulitis and after a brief dose interruption, resumed treatment and completed the trial.
Based on the data we have generated to date, we believe that CTP-543 has a compelling and potentially best-in-class product profile as a treatment for alopecia areata. We are highly encouraged by the Phase 2 efficacy and tolerability data for the 8-milligram and 12-milligram twice-daily doses. We look forward to advancing this product candidate into Phase 3 and moving it further on its path toward offering a new treatment option for patients with alopecia areata, a community that suffers with no FDA-approved treatment options today.
Now turning to CTP-692, a deuterated form of D-serine that we are initially developing as an adjunctive treatment for schizophrenia. The Phase 1 results give us confidence that our deuterium modification has the potential for a much safer product profile than that of non-deuterated D-serine. CTP-692 has demonstrated multiple advantages compared to non-deuterated D-serine in our non-clinical program. In addition to a dramatically improved renal safety profile, we saw much higher brain exposure in rats with CTP-692 compared to D-serine.
In our Phase I clinical trial, CTP-692 displayed favorable pharmacokinetics with significantly lower inter-subject variability than has been reported for D-serine. The safety assessments in the single and multiple ascending dose trial show that CTP-692 was well-tolerated over a dose range tested, which included the doses to be evaluated in Phase 2 testing.
Importantly, consistent with our non-clinical data, key blood and urine markers of kidney function did not indicate any signs of renal impairment. The Phase 1 clinical trial for CTP-692 was presented in early September at the European College of Neuropsychopharmacology Conference in Copenhagen. The poster presentation was very well received, and there is high enthusiasm from a broad psychiatry community for a new mechanism to treat schizophrenia.
Taken together, our data suggest that we will be able to explore a sufficient dose range in our Phase 2 trial to evaluate the therapeutic efficacy and safety of CTP-692. The Phase 2 trial will be a robust study evaluating one grams, two grams and four grams of CTP-692 once-daily versus placebo over a 12-week treatment period. We intend to randomize approximately 300 patients, who are stable on their existing antipsychotic medication. The primary endpoint will be the change in PANSS total score, a commonly used rating scale for schizophrenia studies. We expect to have data by year-end 2020.
Looking ahead, we are very happy to be hosting a webcast event next week with Dr. Joe Coyle, who currently serves as Director of the Laboratory for Psychiatric and Molecular Neuroscience at McLean Hospital. He is a Professor of Psychiatry at Harvard Medical School and is an esteemed thought leader in the field of psychiatry and schizophrenia. Dr. Coyle's lab is focused on understanding the neurobiology of serious mental illness and his work has been very influential in developing more effective neuropsychiatric treatments, including for schizophrenia.
At next week's webcast event, Dr. Coyle will further discuss the opportunity for CTP-692, including the NMDA mechanism and the utility of D-serine for schizophrenia. We look forward to an informative discussion with Dr. Coyle and hope that you will have the opportunity to join us.
Let me pause here and ask Marc to now review the financial results.
Marc Becker -- Chief Financial Officer
Thank you, Jim.
As I review our third quarter financial results, please reference the financial tables found in today's press release. Research and development expenses were $13.5 million in the third quarter of 2019, compared to $11 million in the third quarter of 2018, an increase of $2.5 million.
The increase in research and development expenses relates primarily to the clinical development of CTP-543, including multiple ongoing clinical trials, as well as increased expenses associated with the manufacturing of CTP-692 to support ongoing clinical development. As a reminder, our financial resources are dedicated to these proprietary candidates. For our partnered programs, including AVP-786, all development costs are the responsibility of our collaborators.
General and administrative expenses were $4.7 million for the third quarter of 2019, compared to $6.3 million for the same period in 2018. The decrease of $1.6 million is primarily attributable to decreases in legal and employee-related expenses.
Our net loss for the third quarter of 2019 was $17.2 million, or $0.72 per share, compared to a net loss of $17.4 million, or $0.74 per share in the third quarter of 2018. Finally, we ended the third quarter of 2019 with $121.5 million in cash, cash equivalents and investments.
We expect our cash burn for the year to be approximately $59 million, which is net of $16 million in escrow proceeds received from Vertex in the first quarter. Under our current operating plan, including the planned advancement of CTP-543 into Phase 3 development next year, we believe our cash position is sufficient to fund the company through 2020.
This concludes our prepared remarks, and we would be happy to answer any questions.
Questions and Answers:
[Operator Instructions] Your first question comes from Adam Walsh of Stifel. Your line is now open.
Edwin Zhang -- Stifel, Nicolaus & Company -- Analyst
Hi. This is Edwin Zhang on for Adam. Thanks for taking the questions. My first question is on pipeline. Beyond 543 and 692, what are the next potential clinical program emerging from your pipeline? And I have a follow-up.
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
Yeah. Well, thanks very much for the question. This is Roger. So, we certainly have an ongoing effort in pre-clinical pipeline compounds and have a number of exciting entities that potentially could come forward. But as we've communicated previously, we think that the most effective use of our assets right now is to conduct pipeline expansion by looking at additional indications for existing clinical compounds. In particular, for 692, we believe that there are multiple neuropsychiatric indications that are potentially treated by that neurotransmitter.
Edwin Zhang -- Stifel, Nicolaus & Company -- Analyst
Okay. We know you have named a new Chief Legal Officer. Related to this appointment, is there any new strategic shift on the current IP issues? And also, can you remind us the legal milestone in the coming months? Thank you.
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
Well, in terms of legal milestones. As you may be aware, we have filed, as I discussed, a challenge to the PTAB ruling and intend to vigorously dispute that going forward. In terms of the appointment of a new Chief Legal Officer, that's really to strengthen our executive team to oversee the legal function as a whole and to give us strength as we move forward in our legal endeavors.
Edwin Zhang -- Stifel, Nicolaus & Company -- Analyst
Okay. Thank you.
Thank you. Your next question comes from Difei Yang of Mizuho. Your line is now open.
Alexander Lim -- Mizuho Securities -- Analyst
Hey. Good morning, guys. This is Alex on for Difei. Thank you for taking the questions. So first one on CTP-543. Could you remind us the considerations that went into testing both QD and BID dosing? And then for the Phase 3, do you expect to test both dosing regimens or just one, assuming the QD trial shows similar efficacy and safety?
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
Yeah. Thanks for the question, Alex. So as we've indicated, with CTP-543, this is a compound and a mechanism that's never really been studied in terms of its dose regimen in the context of alopecia areata. And primarily, our hope is to better understand the pharmacokinetic, pharmacodynamic relationship and to assess if there are opportunities to simplify the dose regimen or otherwise to discover how best to administer the compound for treating the disease. In addition to that, it has the benefit of increasing the number of patients who have been exposed to the compound and decreasing the burden on patients who are going to be in the Phase 3 study.
So in terms of what we expect to do going forward into Phase 3, we are currently assessing that. We won't really be able to answer the question until we've spoken with FDA. We do think that both 8-milligram and 12-milligram twice-daily doses are -- and, of course, depending upon what we see with the dose regimen studies, the 16 and 24 may be appropriate for the Phase 3 studies. However, I'll also note that, as we've stated, we have seen some better results, particularly at the higher dose response with the 12-milligram than with the 8-milligram doses. So, this is something that we're actively assessing and we'll be talking about with the agency.
Alexander Lim -- Mizuho Securities -- Analyst
Okay. Great. And then just switching to 692 and the Phase 2 trial design. Do you expect 692 to have efficacy on the positive symptoms? And then maybe remind us the rationale for measuring outcomes on both positive and negative symptoms?
James V. Cassella -- Chief Development Officer
Yeah. Hi. This is Jim. So, yeah, so we -- the literature tells us that D-serine is very special in many ways and that it does support improvement on both positive and negative symptoms as well as in cognitive functioning. So, our rationale for looking at the total PANSS score, which is the primary endpoint, encompasses all of those domains. So, as our primary endpoint, we'll be looking at total score, which covers a positive, negative and sort of general psychopathology. So, that's our primary endpoint.
For looking at the subtypes of positive symptoms and negative symptoms, we will be able to pull out those domains as secondary analysis as we go forward. But the literature does tell us that we can move positive symptoms and negative symptoms as well as improved cognitive functioning. So, we're really looking at the Phase 2 trial as a way to really gauge the effects on the overall improvement in the patient, as well as looking at individual domains of their symptomatology.
Alexander Lim -- Mizuho Securities -- Analyst
Okay. Great. And just one last quick one if I may. Anything -- could you share what would be a clinically meaningful improvement in the positive versus the negative symptoms there on the PANSS score?
James V. Cassella -- Chief Development Officer
Again, we're powered for looking at the total change score in the PANSS. So the powering is designed to show that we will have at least a five-point improvement over placebo in the total score. And that's how we've designed the trial to look at the overall total score. So, a five-point difference versus placebo is the powering and also believe to be clinically meaningful.
Alexander Lim -- Mizuho Securities -- Analyst
Okay. Great. Thank you very much.
[Operator Instructions] Your next question comes from Esther Hong of Janney. Your line is now open.
Esther Hong -- Janney Montgomery Scott -- Analyst
Hi. Thanks for taking my questions. So on CTP-692. So, there have been some investigator-sponsored studies of non-deuterated D-serine. Can you provide any additional background on those studies, the outcome, if -- how those studies looked at primary endpoints? And did they use the PANSS score? Any sort of background information on non-deuterated D-serine? Thanks.
James V. Cassella -- Chief Development Officer
Sure. Absolutely, Esther. Thanks for the question. And it's a great question because D-serine has a long history, actually, the NMDA hypothesis, the hypofunction hypothesis goes back over 20 years. And this has been an area of interest for a long time. There have been probably around a dozen studies that have looked at D-serine in the clinic, and a good portion of those studies have been positive. To answer your question specifically about some of the details, they do use PANSS. It's commonly used.
People have looked at the total score like we're doing. And in the cases where there have been positive results are reported, they do see movement in the total PANSS. And when you look specifically at the subscales, you can see movement on the positive symptoms and on the negative symptoms. And I think the movement on the negative symptoms is a special hallmark of the D-serine literature. I think when we've looked at all the papers that have been published previously, we looked at the ones that have been positive and the ones that have been negative and showing clinical benefit.
There are some differences between those studies and some of the studies, where there's been positive results have been very educational for us in designing our trial. But we also look at the studies that haven't shown positive results to see what we can glean from those studies as well, and whether they've looked at the drug on top of a drug like clozapine or they've looked at in-patients or looked at different varieties of patients.
We also learn from that in our inclusion and exclusion criteria. So basically, we've talked with the KOLs that have been involved with these -- with D-serine for a long time. We've looked at those studies, and we really have designed our Phase 2 program and looking forward for our Phase 3 to be optimally designed to really pull out the best benefit.
And Roger?
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
Yeah. So thanks, Jim. A couple of other comments in general about the clinical studies with D-serine and how they inform CTP-692. One of them is that the studies, which have shown more mixed results were conducted at a lower-dose level. So that was at the 30-milligram per kilogram dose level or roughly two grams per patient per day. And as you look at the studies that were conducted at higher doses, those appear to be uniformly positive. So, that's one of the things in terms of thinking about the PK/PD relationship that has led us to think about the doses that we're going to use.
As Jim noted, we see a substantially higher exposure in the brain in our pre-clinical models with CTP-692 than we do in D-serine. And so we expect that the doses that we are assessing in the Phase 2 study, going up to four grams per day per person, adequately covers the dose range that's going to give us a very good readout on the properties of 692 as adjunctive treatment for schizophrenia.
And finally, one of the things that we pointed out in prior discussions of 692 is that it has -- in our study, it's remarkably low inter-person variability in the PK work that we did in both single and multiple ascending dose assessments. And that's in contrast to what's been reported for D-serine, which has been stated to have a high level of variability in clinically relevant doses. So, I think all of those point to a favorable profile as well as, of course, the improved renal safety that we hope to obtain for 692.
Esther Hong -- Janney Montgomery Scott -- Analyst
Okay. And then just a follow-up. Can you speak a little bit then about the potential expansion opportunities for 692? Will you wait until data from the Phase 2 study in symptoms associated with schizophrenia or any thoughts on that? Thanks.
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
Well, as we've indicated previously, CTP-692 is a deuterium-modified version of a native -- a human endogenous neurotransmitter, which is altered, certainly it's schizophrenia and there's evidence of alterations in a number of others neuropsychiatric indications as well. We think that this is -- there's a lot of overlap in neuropsychiatric disease. And if we see movement in schizophrenia, that's certainly going to be a positive indicator for its potential in other disease states.
We haven't made any decisions yet as to whether we're going to move forward in additional indications prior to the readout of the Phase 2 study, but that's something that we're actively assessing. As far as the specific indications, there are multiple disease states, which there is some indication may be susceptible for treatment with 692, but we're not ready to identify a specific one at this time.
Esther Hong -- Janney Montgomery Scott -- Analyst
Okay. Thank you.
Your last question comes from Robin Garner of LifeSci Capital. Your line is now open.
Robin Garner -- LifeSci Capital -- Analyst
Good morning. And thank you for taking my questions. I'd like to ask you a few questions on CTP-692. Could you elaborate further on what aspect of its structure might be leading to that lower inter-person variability?
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
Hi, Robin. Thanks for the question. We really don't know what all the variables are because the metabolism of both D-serine and CTP-692 is fairly complex. It has active transport. This is not a compound that is passively uptaking this amino acid and went pass-through membranes by itself. So, there is an active transport aspect to its absorption both from the periphery or from the gut into the periphery and the periphery into the CNS. It is interesting to us that we see continued very high levels of absorption with 692, which is essentially dose linear, as we move up to extremely high levels of absorption.
So it seems like a great substrate for the transporters. And as I noted, we also see much higher brain levels relative to the periphery. So in terms of the overall pharmacokinetics, we know that it's well recognized by the endogenous transporter system and probably is slower in terms of its degradation by all of the mechanisms that degrade the compound. But in terms of really being able to nail down the specifics, I would guess that it's contribution of multiple effects but we can't give you a specific right now.
Robin Garner -- LifeSci Capital -- Analyst
Okay. Thank you. And also, given the range of studies that we've already seen within D-serine, do you have any thoughts on -- or can you share kind of what's the appropriate time point for a primary endpoint?
James V. Cassella -- Chief Development Officer
Yeah. So the studies have ranged in duration from a few weeks out to 16 weeks. When you look at the data, we think that you can see effects as early as around two weeks. And we're -- we decided on a 12-week treatment course. We believe that, that gives us the best opportunity to look at the establishment of the effect and a little bit of the durability of the effect. And clearly, if we're looking at things like negative symptoms, it gives us the opportunity to really see those things grow to their full extent as well. So, I think that we've optimized on 12 weeks by a combination of looking at the literature and talking to a lot of the experts in this space.
Robin Garner -- LifeSci Capital -- Analyst
Okay. Great. Thank you. That's all for my questions for today. Thank you.
Thank you. I am showing no further questions. At this time, I would now like to turn the conference back to Ms. Justine Koenigsberg.
Justine E. Koenigsberg -- Senior Vice President, Corporate Communications and Investor Relations
Thanks. We'd like to thank, everyone, for joining us this morning. Please note that we will be participating at both the Stifel and Jefferies London Conferences later this month, and certainly hope to see many of you there. This concludes today's call. Thank you for joining us.
Duration: 25 minutes
Call participants:
Justine E. Koenigsberg -- Senior Vice President, Corporate Communications and Investor Relations
Roger D. Tung -- Co-Founder, President and Chief Executive Officer
James V. Cassella -- Chief Development Officer
Marc Becker -- Chief Financial Officer
Edwin Zhang -- Stifel, Nicolaus & Company -- Analyst
Alexander Lim -- Mizuho Securities -- Analyst
Esther Hong -- Janney Montgomery Scott -- Analyst
Robin Garner -- LifeSci Capital -- Analyst


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Richmond Hill councillor on Remembrance Day banner slammed for not being a war veteran
Coun. Greg Beros is a reservist, but has never served in combat
A Richmond Hill councillor is facing backlash after he was featured on one of the city's Remembrance Day banners with "lest we forget" written on the top — even though he is alive, and never served in active combat.
Coun. Greg Beros says he has been a reservist lieutenant in the Royal Canadian Air Force since 2016. According to his bio on the city's website, he also works as the "assistant training officer with 778 Banshee of the Royal Canadian Air Cadets."
Richmond Hill resident Joel Clements told CBC News he feels the councillor may be exploiting the definition of a war veteran by appearing on a banner.
"I was kind of shocked because the banners say across the top Lest we Forget — and here's a picture of a living, non-veteran city councillor," he said.
Clements says he has a passion for Canadian military history. He reached out to the Royal Canadian Legion branch that is responsible for the banners, and found out it had a "unique" definition for the term veteran, he said.
According to the legion's website, a veteran is "any person who is serving or who has honourably served in the Canadian Armed Forces, the Commonwealth or its wartime allies, or as a Regular Member of the Royal Canadian Mounted Police, or as a Peace Officer in a Special Duty Area or on a Special Duty Operation, or who has served in the Merchant Navy or Ferry Command during wartime."
That differs from the federal government's definition, which is stated as "any former member of the Canadian Armed Forces who successfully underwent basic training and is honourably discharged."
The Legion says Beros meets its definition of a veteran.
"[Beros'] family chose to honour the fact that he is serving as a military member," said Pamela Sweeny, executive director of the Royal Canadian Legion Ontario provincial command. She said the legion considers anyone currently serving to be offering their lives and therefore, they can be considered a veteran.
"We believe a veteran, is a veteran, is a veteran."
Clements sees the definition of a veteran differently.
"We associate Remembrance Day with people who have died fighting for our country or our veterans of combat or wartime service," Clements said.
"I find it a little bit disturbing to see this banner there alongside a local 23 year old who was killed serving the country in Afghanistan."
Expanding public awareness
Beros told CBC News that the banners are a legion program and he's aligned with the legion's definition of a veteran.
He confirmed he was never sent overseas, and that he enrolled with the air force three years ago. Despite that, he says the focus should be on what the legion is trying to achieve with the banners.
"The promotion of the legion is to remember those who are currently serving and those that have served. The legion is trying to educate the public on the ever-changing face of a veteran," Beros said.
As an example, Beros said, young people who have served in Afghanistan are often not recognized as veterans — so it's important that people understand that veterans can be more than just "your grandfather."
He says his family paid for the banner to be put up.
Social media concerns bubble
Clements shared his concerns about the banner in a post on his Facebook page and received dozens of comments.
Many people have replied to his post saying the banner may be considered an abuse of power on Beros' part. Others said Remembrance Day is a time to "remember those who did serve" and the banner could be considered "just plain tasteless."
Clements said he understands the legion's definition of a veteran from a membership perspective, but added that the traditional understanding of the word is pretty clear.
"This is about remembering people who fought and died or fought and survived," he said.
"Remembrance Day has always been about wartime service and remembering that sacrifice."
With files from Natalie Nanowski


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Ardistan (Esfahan)
Ardistan (Esfahan) is geographically located at latitude 33° 22' 48" North of the Equator and longitude 52° 22' 11" East of the Prime Meridian on the Map of World. The following locations related to it are represented by the nearest distances two points and may not be nearest by road.
Borujan (Chahar Mahal-e Bakhtiari)
Farrokhshahr (Chahar Mahal-e Bakhtiari)


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Other services from Comerciales Fremme, S.A.
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Clowes, M.B.
Co Author Listing * Finding Picture Edges Through Collinearity of Feature Points
* On Seeing Things
* Perception, Picture Processing and Computers
* Pictorial Relationship: A Syntatic Approach
* Picture Descriptions
* Scene Analysis and Picture Grammars
* Transformational Grammars and the Organization of Pictures
7 for Clowes, M.B.
Index for "c"


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Roofing & Window Contractor Niantic CT
D.H. Radomski has provided exterior home remodeling services to the Niantic CT area since 1976. Our customers trust us to provide reliable, efficient, prompt replacement and installation services, and we've built our reputation on that. As a family-owned, full home-service company, we understand that trust means everything, especially when asking a contractor to perform renovations to your home. That's why we also offer some of the best, and most affordable warranties in the area.
Roofing Professionals
Our team of experts understands what it takes to protect your home from the harsh northeastern winter conditions. That's why homeowners in the Niantic CT area turn to D.H. Radomski for all of their roofing needs. We only use best-in-class materials from the most reputable manufacturers in the business, so that you can have the peace of mind that comes from quality workmanship and an unmatched warranty. You can rest assured that that your roof will be completed in a timely, efficient manner, because we believe you deserve the best we have to offer.
Expert Window Replacement and Installation
Windows are unique to each and every home, and no two are quite alike. From the framing and construction to the design and materials, our window service offers a personalized touch to ensure that you're getting the best deal available. Whether you need a single window installation or a full home replacement, D.H. Radomski does it all. Call us today for a free estimate!


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Wall-to-wall, secure and reliable Wi-Fi that works for your home
We specialize in adapting systems for large and difficult homes
We solve the problem of Wi-Fi in homes
You don't have complete reliable coverage throughout your house
Wi-Fi is an Art – not a science
Wi-Fi installation is more of an Art than a Science. Experience helps layout better designs – but ultimately the only way to ensure reliable results is to thoroughly test every installation.
Sometimes even well-designed installations still require tweaks to reach peak performance. This can be as simple as relocating or repositioning an AP, and sometimes additional resources are needed.
Omaha Communications – a division of InPath
We have specialized in solving difficult network problems with simple solutions since 1994 – over 25 years! We know that our reputation depends on good outcomes and we promise to do our best for our customers.
We back up that promise
with our 30-Day money-back guarantee
or call us right away
(402) 346-0200
Wi-Fi and the Internet of Things (IoT)
Modern homes are also filled with devices that depend on data from the internet. These ranges include Smart Thermostats, Smart Lighting, online Doorbells, IP Cameras, Electronic Personal Assistant (like Alexa), and more. As we fill our homes with more and more of these conveniences Wi-Fi becomes even more essential.
Wi-Fi is the newest "Essential Utility"
Reliable Wi-Fi is more important than ever. In the age of information, the Internet has emerged as the Fifth Essential Utility (gas, water, electricity, telephone, and Wi-Fi/internet). Modern homes depend more on reliable WiFi.
For many, our homes have become a secondary workplace. For some, it has become the primary workplace! Our kids require the internet for school work and classes. More and more our entertainment also relies on streaming the Internet as well.
We have the answer for reliable, secure Home Wi-Fi with total coverage for all types of homes
When we started designing and installing Wi-Fi solutions in homes most of our Wi-Fi installations were in "exceptional" larger homes (larger than 4000+ SF). Most people in smaller homes would install a wireless router and they settle for whatever the coverage that is offered. But as Wi-Fi became more important full home coverage became more important as well. At first, the common reaction was to add more Access Points or "Range Extenders" and the like. But these rarely worked well and seldom made the homeowners happy.
Meanwhile, homes got bigger (according to the 2019 Census the Median Home nationally is over 2300 SF). And Wi-Fi continued to become more important as well. The result is that unreliable Wi-Fi networks and poor Wi-Fi coverage has become a problem for the "everyman".
But, the "range extenders" and "extra AP's" and other "home remedies" do not solve the problem. Homeowners now are looking for help.
Sometimes you don't want to "Do It Yourself" – call an expert
Homeowners become frustrated trying to solve their Wi-Fi network problems by themselves and often even when working with professionals. We talk to customers all the time that tried all the "mainstream" and "off the shelf" solutions from the "Big Box" stores. They attempt to solve the problems with multiple AP's, range extenders, mesh networks, etc. The results are very often miserable networks that are complicated and not reliable over time or which never even work in the first place.
Omaha Communications solutions are different – our solutions are designed to provide total home coverage that is secure, reliable, and simple.
Omaha Communications Wi-Fi System Architecture
The network we install in your home will first and foremost be simple to use. larger homes frequently require multiple "Access Point" to provide complete and reliable coverage. But, no matter how many physical access points are required there will just be one Wi-Fi network (SSID) to connect to no matter where you are in the house.
You can move throughout the house and the network will intelligently connect you to the best Access Point. Everything
is automatic and seamless.
Ongoing maintenance and support
After installation, we test your coverage, make required tweaks, or add resources if needed. We know that our reputation depends on good outcomes and we always do our best for our customers. And that is why we offer a 30-day money-back guarantee.
We provide annual remote maintenance for those who need ongoing support for their Wi-Fi network.
Ready to build better communication?
Looking for help and advice around home Wi-Fi networks?We'd love to talk
or call us right away
(402) 346-0200


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Atlas Wine Pro
Vietti, Barbaresco Masseria 2014 (Magnum)
Regular price £130
Items Available: 1
Bottle Size: 150cl
Region: Italy: Piedmont
Colour: Red
Style: Still
Grape Variety: Nebbiolo
Critic Score: The 2014 Barbaresco Masseria is superb. Dark, ample and structured, the 2014 captures all the pedigree of this important Barbaresco vintage. As always, the Vietti's Masseria is a wine that has Barolo-like structure and depth, partly because it is vinified and aged pretty much along the same lines as those wines. I expect the 2014 will require at least a handful of years to shed some tannin and start showing some of its inherent inner sweetness. There is so much to look forward to. Bright acids and a firm spine of tannin give the red-toned fruit energy and vivacity throughout. Tasted October 2017. 94 Points, Antonio Galloni, Vinous.com


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Long-term care facilities and communities provide an invaluable service throughout the country. In November, we bring awareness to these facilities and what exactly it means during Long-Term Care Awareness Month.
"Long-term care" encompasses a wide range of healthcare facilities and services, including assisted living communities, home health assistance and other technologies or services where staff are on-hand to provide assistance to those who need it. Care provided is not always medical, and according to the U.S. Department of Health and Human Services, the majority of Americans 65 or older will require long-term care at some point in their lives.
Preparing for long-term care sounds daunting, but with the right mindset and a little insight, everyone can create the long-term care plan for themselves. Check out this helpful guide from AARP filled with resources and frequently asked questions to help you prepare.
TekTone is proud to provide communication systems to long-term care facilities around the world, and we are grateful for the staff and volunteers that keep our communities running smoothly and providing vital care to those who need it.


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SPOKANE VALLEY – Oct. 9, 2018 – On November 8th, Kaspien (formerly etailz), the number one FBA retailer, will speak at the Outdoor Retailer Winter Market on key Amazon topics for the outdoor industry.
Marketing Director Keri Rhodes will present "Understanding Amazon and its Impact on Your Business" at the 2018 Outdoor Retailer Winter Market. The presentation will briefly cover the basics of selling on Amazon before exploring practical solutions to common frustrations faced by the outdoor industry on Amazon.
"We're excited to meet and strategize with brands at OR Winter. Amazon can be a tricky place to navigate for new and experienced brands alike, so it's always rewarding to help light the way," said Keri. "Kaspien is based in the Pacific Northwest, and we take advantage of the recreational opportunities that provides. Working with the outdoor industry feels close to home."
Presentation attendees will learn:
- What manufacturers can do to protect their business on Amazon;
- How to determine the best selling method for their brand on Amazon; and
- What specialty retailers can do to improve their business on Amazon.
The presentation will be given in the Colorado Convention Center on Thursday, November 8th, from 2:00 to 3:00 pm.
Kaspien will also be located at booth #51000-UL for the duration of the trade show. Attendees with questions about anything from launching on Amazon to global expansion can stop by the booth to speak with the Kaspien experts.
About Kaspien
Kaspien is the most sophisticated online retailer in the business with over $500 million in lifetime marketplace sales. Founded in 2008 and profitable since 2009, Kaspien has rapidly grown in size and capabilities over the last decade, becoming the partner to leading brands on Amazon, Jet, eBay, Walmart, and Wish. The company was acquired by Trans World Entertainment Corporation in October 2016. Connect with us on Facebook, Instagram, Twitter, and LinkedIn.


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Alexandra Lee is the recipient of the 2017-2018 MBA Scholarship offered by the SNVC Institute. With no doubt, she embodies the principles of "The 7 Habits of Highly Effective People" training offered by the SNVC Institute.
Alexandra is a person who has looked at situations "Proactively" (Habit 1) by having an active role turning challenges to opportunities when observing dissatisfaction within a student organization to produce tangible victories.
Being involved with a variety of organizations and activities while pursuing an undergraduate degree at Longwood, she "Began with the End in Mind" (Habit 2) to achieve specific goals while serving as the Main Stage Chair for a successful Oktoberfest 2016; organizing fund raising events for FACES and the Environmental Club; initiating environmentally sustainable practices in the Longwood Dining Facilities; implementing incentives to improve recycling efforts on campus; and founding the Epsilon Chapter of Epsilon Eta (an environmental honors fraternity). Her leadership roles have included serving as President of the Honors Student Association, President of Epsilon Eta, a member of the Mortar Board, participation in the Mountain Lake Leadership Conference, and completion of the Joan of Arc Leadership Program. These are just some of her accomplishments. She has accomplished this while maintaining a GPA of 3.5.
She knows the importance of "Putting First Things First" (Habit 3) and has the innate ability to "Think Win-Win" (Habit 4) because her dedication to leadership that impacts more than herself. The impacts from her actions are sure to help our community long after she has graduated from Longwood.
A leader needs to "Seek First to Understand" (Habit 5) and work with diverse groups of people to achieve goals (Synergy – Habit 6). Yes, she has demonstrated these Habits as well.
Continuing to "Sharpen the Saw" (Habit 7) with knowledge gained from her MBA degree, there is full indication that her leadership skills will continue to grow and prosper with any endeavor she pursues.
We are proud to have her as the recipient of this scholarship.


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The Neighborhood Watch Program is a crime prevention program that enlists active participants of residents in cooperation with law enforcement to reduce crime, solve problems, and improve the quality of life in the area in which they live.
The Wheeling Police Department facilitates these programs by holding community meetings, special events, and providing educational training and communications. Neighborhood Watch participants are also encouraged to take part in programs such as the Citizen Police Academy and the National Night Out Against Crime, which is held on the first Tuesday in August.
To access the Crime Watch Calendar, Click Here.
The following Neighborhood Watch meetings are held throughout the City of Wheeling:
Date/Time: Second Thursday of the month, 7 p.m.
*(No Meeting in December, January or February)
Location: Warwood Christian Church - 131 North 17th Street
North Wheeling
Date/Time: Third Thursday of the month, 7 p.m.
Location: Riverview Towers - 601 Main Street
Wheeling Island
Date/Time: Fourth Tuesday of the month, 6 p.m.
*(No meeting in December or January)
Spring/Summer: Wheeling Island Community Shelter - Wheeling Island Marina
Fall/Winter: Island Christian Church - 59 Zane Street
East Wheeling - Downtown
Date/Time: First Monday of the month, 6 p.m.
Location: Wheeling Police Headquarters - 2115 Chapline Street
Center - South Wheeling
Date/Time: Fourth Tuesday of the month, 6:30 p.m.
Location: Trinity Lutheran Church - 3536 Eoff Street
Woodsdale - Edgewood - Pleasanton
Date/Time: Second Tuesday of the month, 7 p.m.
Location: Temple Shalom - 23 Bethany Pike
Elm Grove - Springdale
Date/Time: Third Wednesday of the month, 7 p.m.
*(No meeting in December, January or February)
Location: Elm Grove Civics - 21 Sycamore Avenue


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At 37, this entrepreneur left his business development job to be a baker
Kenneth Seah started Kki Sweets with his wife Delphine Liau with a simple aim: To create a happy place for people to enjoy delicious, Japanese-inspired cakes.
When Kenneth Seah was growing up, he always looked forward to birthdays. His mother often baked at home so there were always cakes in the house, especially during special occasions.
"I grew up loving sweets, loving cakes. I guess that's somehow processed in me and subconsciously, I enjoyed that," said Seah with a smile as he reminisced about those fond memories.
WATCH> Cooking Indian food with a French twist, inspired by grandma's recipes
In 2007, Seah's first trip to Tokyo opened his eyes to the world of exquisite Japanese cakes. He recalled, "It was mind-blowing because the texture, the flavours, everything was very well-balanced. I never knew that cakes could be like that."
Upon his return he tried to find something similar but there wasn't anything that came close. So he and his wife Delphine Liau started their own patisserie Kki Sweets in 2009, serving Japanese-inspired mousse cakes and entremets together with tea and specialty coffee. Recently, they moved into a brand new space along Seah Street.
"Kki basically means cake in Japanese. It is very straightforward and it's what we want to do. No fancy French name, just cakes in the simplest form," Seah explained. "It's very Japanese-inspired, in terms of the balance and texture."
Sparked by Japanese pastry legends Hidemi Sugino and Sadaharu Aoki, Seah was 37 when he left his job in business development and taught himself how to bake.
He shared, "My background is in engineering. I never really baked until we opened Kki and it was really a leap of faith because we didn't know whether it would work out, whether it would taste good."
While the lack of formal training meant a steeper learning curve, Seah felt that it had also given him a certain boldness. "Sometimes I'm glad that I didn't have that background. Then I have no boundaries, I can go crazy, and I think that's a plus point for me," he said.
He is also a stickler for using quality ingredients. "It has to be at the highest quality when you serve it out, because the person has taken time to come here to eat that and you should honour that. My mum never stints on ingredients and that has stuck with me always."
His techniques and sensibilities are informed by art, fashion and architecture, all distilled into exquisite edible structures. He even plays with different fruit combinations that people never think would work.
Case in point: the whimsical "J" is an ingeniously shaped "potted plant" made of black sesame mousse, yuzu cremeux and matcha. Another too-pretty-to-eat dessert combines Japanese tomato, strawberry and red pepper.
Kki's interior is designed with Japanese minimalist aesthetics. There are no cake stands nor fancy display cases. A long communal table interspersed by bamboo plants forms the centrepiece so diners have some privacy even though they're seated near each other. Dessert images are deliberately omitted from the menu and diners are invited to let their imagination guide their taste preferences.
"It's more like a dessert studio – when you order it, we plate it out," said Seah. "It gives us more room to play with creativity here. We can put in different textures and flavours, it's something you won't be able to do if you had a cake display."
The communal table extends right into the kitchen where Seah leads the preparations while Liau manages the front of house. He explained, "We didn't want the kitchen to be separated from the diners. So it's very much like your home, everyone sees what's going on. There's more interaction rather than a separation."
Besides satisfying the palate of discerning cake connoisseurs, Seah also has another mission: To nurture the next generation of pastry chefs. "There are a lot of wonderful young pastry chefs and it will be a pity for them to end up overseas, working somewhere else. We hope that this place can also inspire them. They can come here and say that it is possible to do something like that," he enthused.
The couple are gratified to have a loyal clientele that includes those who bring their children to enjoy the desserts they had loved while they were dating.
Seah said, "A lot of our customers come in, hoping to chat with us. It's like a relationship, it's like coming to your friend's house.
"If you are having a bad day and if that cake makes you feel a lot better, and if it inspires you, if this space gives you something to take away that is not tangible, that's good enough for us."
Adapted from the series Remarkable Living (Season 3). Watch full episodes on CNA, every Sunday at 8.30pm.


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Paul Palmer papers
Scope and Contents
This three box collection of approximately five hundred items consists of Paul Palmer's business correspondence, 1923-1960. The majority of the letters are to Palmer from such prominent literary and political figures as: Eli Culbertson, Clarence Darrow, Ford Maddox Ford, Joseph P. Kennedy, John F. Kennedy, Anne Morrow Lindbergh, Charles A. Lindbergh, Henry L. Mencken, John O'Hara and Alexander Woollcott. In some cases drafts of articles were included with the letters, some of these were never published. The letters from Palmer requesting writers to pursue certain topics in articles for publication and the writers' responses to him are revealing. Many of the letters express intelligent opinions, or highly emotional reactions to the various political issues, and thus represent illuminating commentaries on the temper of the times. This collection of papers is a valuable source for research in political and literary thought of the 1930s, 40s and 50s.
- 1929-1960
Conditions Governing Access
The materials are open for research.
Conditions Governing Use
Copyright status for collection materials is unknown. Transmission or reproduction of materials protected by U.S. Copyright Law (Title 17, U.S.C.) beyond that allowed by fair use requires the written permission of the copyright owners. Works not in the public domain cannot be commercially exploited without permission of the copyright owners. Responsibility for any use rests exclusively with the user.
Immediate Source of Acquisition
Gift of Paul Palmer in 1961.
1 Linear Feet
Language of Materials
Catalog Record
A record for this collection is available in Orbis, the Yale University Library catalog
Persistent URL
The papers consist of Paul Palmer's professional correspondence with prominent literary and political figures soliciting articles for publication. In some cases, drafts of articles are included with the letters.
Biographical / Historical
Paul Palmer was born in 1900. His career in journalism began in 1922 when he became a reporter for the Baltimore Sun. Between 1923-1926 Palmer was first a reporter, and then Sunday editor of the St. Louis Post Dispatch. He was Sunday editor of the New York World from 1926-1930, and a free-lance writer from 1930-1935. In 1935 Palmer became editor of The American Mercury, a post he held until 1939. From 1939-1941, he was a reporter for Reader's Digest. Palmer was Washington correspondent for the McClure newspaper syndicate during 1941. In 1942 he returned to Reader's Digestand became a senior editor. Paul Palmer died on July 2, 1983.
- Culbertson, Ely, 1891-1955
- Darrow, Clarence, 1857-1938
- Editors
- Journalism
- Journalists
- Kennedy, John F. (John Fitzgerald), 1917-1963
- Kennedy, Joseph P. (Joseph Patrick), 1888-1969
- Kenney, George C. (George Churchill), 1889-1977
- Lindbergh, Anne Morrow, 1906-2001
- Lindbergh, Charles A. (Charles Augustus), 1902-1974
- Mencken, H. L. (Henry Louis), 1880-1956
- Nock, Albert Jay, 1872 or 1873-1945
- O'Hara, John, 1905-1970
- Palmer, Paul, 1900-1983
- United States -- Intellectual life -- 20th Century
- Woollcott, Alexander, 1887-1943
- Title
- Guide to the Paul Palmer Papers
- Status
- Under Revision
- Author
- Preliminary inventory by Carol King
- Date
- February 1990
- Description rules
- Finding Aid Created In Accordance With Manuscripts And Archives Processing Manual
- Language of description note
- Finding aid written in English.
Part of the Manuscripts and Archives Repository
Yale University Library
P.O. Box 208240
New Haven CT 06520-8240 US
(203) 432-1735
(203) 432-7441 (Fax)
Sterling Memorial Library
Room 147
120 High Street
New Haven, CT 06511


text:
The guy who carved up novelist Salman Rushdie on August 12, 2022 may have been trying to anticipate the 75th anniversary of the setting of Rushdie's most prestigious novel, Midnight's Children, August 15, 1947. The only thing I've read by Rushdie was an impressive New Yorker review about how Kipling, especially in Kim, had correctly portrayed how South Asia tends toward sensory overload.
But I wasn't aware that 1981's Midnight's Children is Latin American style Magical Realism in the manner of Gabriel Garcia Marquez's 1967 novel One Hundred Years of Solitude. I was charmed by One Hundred Years, but I stopped reading it halfway through because there didn't seem any motivation to find out what happens because it was obvious the author would just change the rules to let whatever he wanted happen. From Wikipedia:
Midnight's Children is a loose allegory for events in 1947 British Raj India and after the partition of India. The protagonist and narrator of the story is Saleem Sinai, born at the exact moment when India became an independent country. He was born with telepathic powers, as well as an enormous and constantly dripping nose with an extremely sensitive sense of smell. …
If I were born in Bombay like Rushdie in 1947, I'd want an extremely dull sense of smell.
The first book begins with the story of the Sinai family, particularly with events leading up to the fall of British Colonial India and the partition. Saleem is born precisely at midnight, 15 August 1947, therefore, exactly as old as independent India. He later discovers that all children born in India between 12 a.m. and 1 a.m. on that date are imbued with special powers. Saleem, using his telepathic powers, assembles a Midnight Children's Conference, reflective of the issues India faced in its early statehood concerning the cultural, linguistic, religious, and political differences faced by a vastly diverse nation. Saleem acts as a telepathic conduit, bringing hundreds of geographically disparate children into contact while also attempting to discover the meaning of their gifts. In particular, those children born closest to the stroke of midnight wield more powerful gifts than the others. Shiva "of the Knees", Saleem's nemesis, and Parvati, called "Parvati-the-witch," are two of these children with notable gifts and roles in Saleem's story.
That sounds lamer than I expected.
But a lot of people like it, so it's probably pretty good.


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