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Now, devotees from across the world can have Darshan of Lord Jagannath at the 12th century shrine in Puri.
However, the devotees have to produce the COVID-19 negative report in order to get an entry into the Puri shrine, one of the four major Dhams for Hindus.
The temple reopened for all devotees Sunday after remaining closed for nine months in wake of the pandemic even as Odisha Governor Ganeshi Lal preferred to have darshan of the deities from outside for not having the mandatory COVID-19 negative report for entry into the shrine.
The Governor, along with his family members and some staff, had to return the state capital after having darshan of "Patitapaban" (the symbolic image of Lord Jagannath seen from outside the temple) as they did not have the COVID-19 negative report, a senior official accompanying Prof.Lal.
Though there was no restriction on the entry of the Governor, who was welcomed by the Shree Jagannath Temple Administration (SJTA) and Puri District Administration, however Prof.Lal volunteered not to go inside on his own after knowing that all the devotees have to submit their COVID-19 Negative Report, a senior official.
The 12th century shrine started its reopening process in a phased manner from December 23. When the servitors and their family members were allowed to enter the temple till December 25, the local residents of Puri got the opportunity in the second phase from December 26 to December 31 evening.
The temple remained closed on January 1 and 2 to be opened for all devotees from across the country from Sunday.
About 17,000 devotees on the first day visited the temple after producing COVID-19 negative reports done within 96 hours and adhering to the COVID-19 guidelines.
The SJTA and the Puri District Administration has implemented a guideline for the devotees asking them to mandatorily wear face mask, sanitize hands, maintain physical distance at all times, not to touch statues or idols inside the temple.
This apart, It is prohibited to take flowers, bhoga, and deepa inside the temple. There will be big containers placed at the entrance, where such items can be dropped if being carried by the devotees, it said.
The devotees also cannot take mahaprasad (bhog) inside 'Ananda Bazar' and Temple premises while chewing of tobacco, paan and spitting inside temple premises is strictly prohibited.
The devotees enter the temple through a queue system and are required to produce their photo ID card like Aadhaar, Voter ID and others. They have to leave their belongings at the designated place outside the temple. They enter into the shine through Lions Gate and exit through north gate.
Meanwhile, the Bhubaneswar Municipal Corporation (BMC) Administration in Bhubaneswar allowed the residents of the Capital city to enter Shree Lingaraj Shrine by adhering to the COVID-19 protocol.
Many temples in the State Capital and in other parts of the state also reopened for the devotes after a long gap of nine months.


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If the date Wednesday, Oct. 21, 2015 sounds familiar to you, it might be because it was just last week. Or perhaps you are remembering that as the "future" destination set and briefly navigated in Robert Zemeckis' Back to the Future Part II.
Viewers will remember Zemeckis' 2015 as a colorful one, both figuratively and also literally in the vibrant color palette of costumes and props, from Marty McFly Junior's distinctive rainbow baseball cap to the iconic hot pink Mattel hover board. Doctor Brown pilots his retrofitted flying DeLorean in a bright yellow coat with a red shirt and a silver visor against Marty's impressive but comparatively low-key self-sizing, self-lacing Nikes. Shiny blue holograms mock the proliferation of Jaws sequels and the rate of monetary inflation, and a stunning display of lights announces the Cubs' World Series win. By all accounts Zemeckis' vision makes our version seem quite muted and dull. But what if I told you that it's not just because of the fashion and technology, and that what he got wrong is not what you think?
If asked to point out inaccuracies in Zemeckis' ambitious portrait of the future, I imagine that most people would likely point to the flying cars and to the hoverboard and hologram technologies. In other words, what is supposed to be different in the future than in the late twentieth century. But to me it seems that the problem is found in the much smaller cultural things that fall short, the things that are supposed to be the same in the future, and that it's not that Zemeckis assumed the future too fantastic, but that he imagined it too consistent.
Because let's face it, our culture and social norms are in many ways quite inconsistent with those of the late twentieth century. I give as one example the famous scene in which Marty borrows a hoverboard from two small children playing outside together unsupervised and Griff Tannen's goons take chase.
Most people would say that the hoverboard is the part of that scene that doesn't track with the real 2015, but I would call that difference surprisingly negligible compared to the idea that there are two young middle-class children in 2015 playing together not only in-person but outdoors and without so-called helicopter parents looking on from nearby. As it stands, the central premise of meeting Tannen in person at the Café 80s in the first place to plan an illegal heist only hangs by the thread of likely NSA surveillance of the more preferred media of communication.
This goes the same for all of the holograms; they assume a person walking outside, looking up rather than stooping like cavemen to tap on their rectangular screens. Yeah, the Internet and the smart phone really killed that dream.
Zemeckis' 2015 is overly optimistic not in assuming crazy trends like inside-out pants and double neckties or in dreaming up fantastic technologies such as self-dusting books and fingerprint-based gadgetry and hands-free video games (Hey! He got that one right! And the fingerprint one, sort of!), but rather in assuming the completely unremarkable sameness of the involved and social nature of people.
He assumes a much more interested and engaged populace, to say nothing of fun and whimsical. Zemeckis' citizen of 2015 drives a flying car like a starship captain, soaring through crowded stratospheric highways; real 2015's citizen is still waiting for those self-driving cars to get big so that he can check his Facebook, Twitter and Instagram on the way to work.
It's not the technologies that set these "futures" apart; it's the way people expect them to be used. Even the very tone used in employing the concept of a predicted future is telling; Zemeckis comes from the old school of thought that future technology will make life shiny, bright and exciting, whereas we on the other end in the real 2015 tend to predict muted-color dystopias.
In short, one of these 2015s is disappointingly off-target and falls short of expectation, and it's not the one in the film. In fact, that 2015 makes our 2015 look like a very pessimistic and antisocial time. It is not that Zemeckis goes too far but that he doesn't go far enough, and that in assuming that old standard "the more things change, the more they stay the same" he fails to predict the huge interpersonal divisions and fundamentally different rules of disengagement that the internet and the ubiquitous computer will culture. And it is this that is indeed "heavy."
Sam Ready is a College sophomore from Atlanta, Georgia.

subset: commoncrawl


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Impossible seeks halal status for plant-derived pork but certification may not be forthcoming
Impossible Pork, a plant-derived product, is seeking halal certification, according to the manufacturer, but it is not clear if certification will be forthcoming.
California-based Impossible Foods released its pork substitute at the beginning of the year. The company's earlier product, the Impossible Burger, was at the end of 2018 halal-certified by the Islamic Food and Nutrition Council of America (IFANCA) under regulations set by Malaysia's Department of Islamic Development (JAKIM).
"We will seek halal and kosher certification as we did with the burger," an Impossible company spokesperson told Salaam Gateway in an email.
IFANCA would not reveal whether it will certify Impossible Pork.
"We do not comment on pending applications for halal certification, but we can confirm if a product is certified or not. We are certifying the Impossible™ Burger," said IFANCA in an email to Salaam Gateway.
"We have not certified Impossible Pork," added IFANCA.
Halal certification for plant-based pork is controversial.
While pork is haram (not permissible) under Islamic law, plant-based alternatives to pork may not contain any haram ingredients.
However, under JAKIM's rules, which are widely regarded as a benchmark for the global halal certification industry, halal certification will not be awarded to a product that starts off from a haram standpoint, such as zero percent alcohol beer.
It is an opinion echoed by other certification bodies.
The UK's Halal Trust, a certifying body, said it would not grant halal certification to a plant-based pork substitute like Impossible Pork.
"I would never certify it even if it is technically halal, because the word "pork" could create problems and confusion," Shoeeb Riaz, operations director at the Halal Trust, told Salaam Gateway.
"Would most Muslim consumers' reaction be positive or negative? And once the genie is out of the bottle, where would you stop?" he added.
IFANCA clarified its policy: "In general, we do not certify products whose names contain certain words that are normally associated with haram products, such as pork."
Impossible Foods did not state whether it was seeking halal certification for Impossible Pork with IFANCA or another halal certification body.
Riaz said it would be a controversial move for IFANCA to certify Impossible Pork.
"Why would IFANCA want to certify a product which has the word pork in it? It would delegitimize themselves amongst Muslim consumers," he said.
Phuture Meat, a Malaysian food start-up that launched a plant-based pork last year, was the subject of media scrutiny following reports claiming the product was halal.
The company denied it was seeking halal certification. "We are currently 100 percent focusing on the Chinese market," Phuture's co-founder, Jack Yap, told Salaam Gateway in August.
(Reporting by Paul Cochrane; Editing by Emmy Abdul Alim firstname.lastname@example.com)
© SalaamGateway.com 2020 All Rights Reserved


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Carl Tielsch founded the Altwasser factory in 1845. It swiftly became second largest porcelain factory in Silesia. After twenty years the factory employeed 1,400 employees. Products of the Tielsch factory quickly became known for its high quality and artistic values. Their quality was compared to porcelain manufactures from Berlin or even Meissen.
Mark used around 1925 with addition used on wares made for Villeroy & Boch
Black Knight Waldenburg Studios Laurel Wreath Made in Germany - Carl Tielsch U.S. export mark used 1920 - 1941.


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Fishing has come a long way — thanks to Minnesota
Few states, or even countries, can match Minnesota's variety and quality of fish, many of which are dependent on smaller fish — fathead minnows especially — to eat.
Walleyes of course are King here. Or Queen — take your pick. Other finned resident bigwigs include bluegills, crappies, largemouth and smallmouth bass, northern pike, muskies, steelhead, lake trout and various sizes and colorations of stream trout, including brook, brown and rainbow.
Over time this vast fishery has spawned countless innovations among Minnesota's 1 million-plus anglers that quite literally have changed fishing history. Revolutions in minnow imitations, bait presentation, lure distribution, boat design, electric trolling motors and fishing electronics are among these homegrown breakthroughs.
1. Tiny fish, big role
Wherever in Minnesota water gathers, including dirty, shallow, low-oxygen ponds where few swimming critters are found, fatheads — Minnesota's most abundant minnow — not only exist, they thrive. Reproducing each year from late May to August, female fatheads spawn multiple egg clutches that can contain 350 eggs per clutch. Without fatheads, which grow to about 2½ inches long while living an average of only about one year, Minnesota wouldn't have the world-class fishery it has. Walleyes, perch, bass, crappies and northern pike devour these tiny fish, as do terns, herons and other birds.
2. Presenting the bait
Four-thousand years after the Chinese first deployed hooks to catch fish, the Lindner brothers, Al and Ron, had an earth-shattering piscatorial idea of their own: the Lindy Rig. Critical as minnows and other live baits are to angling success, bait presentation is equally critical. So the Lindners developed a "sliding sinker'' rig that allows a trolled minnow (or other bait) to trail at various distances behind a bottom-bouncing weight. Soft-biting walleyes can pull the baits into their mouths without feeling resistance from anglers, who allow lines to run through the sliding sinker until setting the hook. Walleye fishing hasn't been the same since.
3. Getting to the fish
Minnesota has long been tops in the design and building of aluminum boats most capable of taking anglers onto, and safely back from, northern fishing waters — Lund, Alumacraft and Crestliner being three notable examples. First on the market was Alumacraft, whose boats were initially built in 1946 by a subsidiary of Flour City Ornamental Iron Works Co. in Minneapolis. Alumacraft's 12-foot-long Model B featured a retail price of $275, no small sum at the time. But advantages of aluminum over heavy and frequently penetrable wooden boats were many, and the shiny metal craft caught on quickly. Lund and Crestliner also debuted prototypes in the '40s and began full production a few years thereafter.
4. Fish await, but rowing is slow
Today shiny 400-horsepower outboards power some upscale fishing boats. Less grandiose were Champion outboards, founded in 1927 by Henry Dolan, Sig Conrad and Dutch Witch of St. Paul. Their first batch of 30 1.5-horsepower motors laid the foundation for Minnesotans C.E. Scott and H.B. Atwater to build Scott-Atwater outboards beginning in 1946. Those brands are long gone, but boat-power innovation still thrives in Minnesota, notably in Mankato, home of Minn Kota electric trolling motors. The company traces its roots to invention of the electric trolling motor in 1934 in Fargo, N.D., by O.G. Schmidt, who called his company Minn Kota in recognition of his home state's proximity to Minnesota.
5. Seeing beneath the surface
Among Silicon Valley's claims to fame is the miniaturization of transistors. Yet California's southern Bay Area can't match Minnesota's hi-tech wizardry in fishing electronics. Vexilar of Minneapolis sold its first product, the Deptherm, in 1960 (it's still offered by Vexilar), followed by many industry "firsts,'' including the first liquid crystal display (LCD) depth finder in 1981 and most recently by inventions incorporating fishing sonar with smartphones. Credit also Jeff Zernov of Brainerd, a marine electronics and video technology expert who invented the first Aqua Vu Underwater Viewing System in 1997. Acquired by Outdoors Insight in 2007, Aqua-Vu remains headquartered in north-central Minnesota.
6. The game changer
Ray Ostrom and Ron Weber of Minneapolis wrote a letter in 1960 that changed their lives and those of every North American angler. Ostrom and Weber's missive to Lauri Rapala in his native Finland requested U.S. distribution rights for Rapala's namesake lure, which mimicked an injured minnow and was little known at the time in the U.S. Remarkably, Rapala responded, "Sure,'' and soon "the Rapala Company'' (later Normark) was established in Ostrom's Lake Street bait shop basement. More good fortune followed when a story about the lure appeared in the issue of Life magazine featuring the life and recent death of Marilyn Monroe. More than 3 million Rapala orders soon arrived, and once again, in Minnesota, fishing history was made.
Photo credits: iStock; Ostrom family; Lindner Media; Vexilar; Alumacraft


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Global Trimax came into operation in 2015 and it manufactures high-quality and safe disinfectant and antibacterial solutions with its Multiway Clean brand, through its production plant at European standards and its experienced staff.
Our Products have the Biocidal License, which is issued by "Republic of Turkey Ministry of Health Public Health Institution of Turkey". In the areas of operation of our company; advanced technology products are put on the market of our country and the world, with a high-quality and safe service mentality.
Global Trimax has aimed to become a symbol of trust in and out of the country; by combining the Multiway Clean brand with quality, affordable prices, customer satisfaction principle and principle of complying with sales conditions.
As Global Trimax; we provide services for the healthy society and healthy environment formation; by offering reliable, environmentally friendly disinfectant and antibacterial products with our Multiway Clean brand, in a way to meet the expectations and needs of consumers.
The Hypochlorus Acid (HOCl), in other words the Active Chlorine, Which is the environmentally suitable disinfectant that is compatible with the new production concept of our century is a biocide with a broad spectrum. It is suggested that HOCl is disinfection 80 to 120 times more efficacious than sodium hypochlorite. HOCl solution demonstrates its Disinfection Effect by disrupting the cell membrane structure of microorganisms, thanks to its high ORP(Oxidation Reduction Potential) value.
Our HOCl Technology is proven pure and stable, laboratory tested and yields excellent results as an effective Disinfection and Sterilization process on microorganisms such as Bacteria, Viruses and Fungus.
Our formulations never contain additives, buffers, and preservatives and remain free of Alcohol, Oil, Parabens, Sulfates, Aldehydes, Phenol, Ammonium or added fragrance.
The Edge in our Safety and Purity
EFFIMAX /effimax/:
strength, efficiency, future, spirit, life, action, passion, energy
True to our name, we are passionate about our formulations and we are energized by our commitment to make a difference in people's lives and in the world.


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Dollar falls further against Japanese yen
- Published
The US dollar has reached another fresh 15-year low against the Japanese yen at the end of trading in Tokyo.
The dollar was worth as little as 81.12 yen at one stage, just above the post World War II low of 79.75 yen.
The dollar's continued fall reflects speculation that the US Federal Reserve will expand its quantitative easing programme.
But Japan's central bankers have also repeatedly threatened further action to curb the recent rises in the yen.
A strong yen is hurting Japanese export companies, which are relied upon to spearhead a recovery in Japan's struggling economy.


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Not what we want to see
We are almost through hatching in our yellow-eyed penguin colonies and have many small chicks. Almost all of them need to be treated for Diphtheria, so it's head down and bum up for everyone trying to save the chicks. If they die, they won't fledge and there won't be any chance of young ones starting to breed to replace the breeders that die - and then the population will never recover. Needless to say that a ferret passing by Stitches' nest is a problem we don't need on top of this. We had a camera on her nest because a pair of penguins that had failed were spotted in the vicinity and we wanted to see if they are being a problem. Now traps are out and our wonderful rabbit hunter has been notified. Lets hope there are enough young rabbits, mice and rats about for the ferret not to take an interest in the young penguin chicks!
December 2022


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Non-aviation services
Aeroexpress Inc. and Sirena-Travel CJSC signed a cooperation agreement, which enabled Aeroexpress tickets sales through the leading Russian distribution system Sirena-Travel GDS.Read more
Railway Transportation
Railway Transportation
Sirena-Travel, JSC, provider of complex technology solutions, offers its customers the option to sell railway transportation "Russian Railways" JSC and the main railway operator of Europe, the German company, Deutsche Bahn.Read more
Universal platform for managing, selling and controlling of transport services for passengers. Modern digital services to passenger service.Read more
Deutsche Bahn
Deutsche Bahn
The company AccessRail (9B), an IT provider of German Railways, Deutsche Bahn, provides technological support to railway carries that desire to sale their tickets and services through the GDS in combination with air transportation.Read more
An innovative solution for agents. Mixvel is a platform for the travel industry that aims to combine all travel services in one tool, in one business process.Read more


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Acting Assistant Secretary for Global Public Affairs Elizabeth Kennedy Trudeau will travel to Bonn, Germany, June 17-20 to attend the G7 Media Ministerial with diplomatic counterparts from each of the G7 countries. While in Bonn, Acting Assistant Secretary Trudeau will discuss the protection of media professionals and journalists, especially in light of the war in Ukraine; the role of media in democratic societies; ensuring access to reliable information and media independence; and cooperation with civil society. During the meeting, the ministers intend to issue a communiqué pledging increased cooperation to support and strengthen independent media as free and independent media is a cornerstone of healthy democracies.
Following the G7 meeting, Acting Assistant Secretary Trudeau will attend the Deutsche Welle Global Media Forum where she will participate in a plenary entitled "Shaping the Future of Journalism in Wartimes." The Acting Assistant Secretary's trip supports U.S. commitments to press freedom and underscores U.S. solidarity with G7 countries working to strengthen democracy.


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text:
Vol 47, No 7 (2019)
- Year: 2019
- Articles: 9
- URL: https://almclinmed.ru/jour/issue/view/50
Full Issue
Cardiomyopathies associated with the DES gene mutations: molecular pathogenesis and gene therapy approaches
Prevention of epileptogenesis as a future strategy for the treatment of epilepsy
Cell technologies in the regenerative medicine of the heart: main problems and ways of development
Application of artificial intelligence in medical data analysis
The current state and promising innovative directions to development methods for bioimplant sterilization
In vitro и in vivo photodynamic therapy of solid tumors with a combination of riboflavin and upconversion nanoparticles
Rationale: Riboflavin (vitamin B2) is one of the most promising agents for photodynamic therapy (PDT). However, its use is limited by the excitation in the ultraviolet (UV) and visible spectral ranges and, as a result, by a small penetration into biological tissue not exceeding a few millimeters. This problem could be solved by approaches ensuring excitation of riboflavin molecules within tumor tissues by infrared (IR) light. Upconversion nanoparticles (UCNPs) can be potentially considered as mediators able to effectively convert the exciting radiation of the near IR range, penetrating into biological tissue to a 3 cm depth, into the photoluminescence in the UV and visible spectral ranges.
Aim: To evaluate the efficacy of UCNPs for IR-mediated riboflavin activation in the depth of tumor tissue during PDT.
Materials and methods: The water-soluble riboflavin flavin mononucleotide (FMN, Pharmstandard-UfaVITA, Russia) was used as a photosensitizer in in vitro and in vivo experiments. The in vitro experiments were performed on human breast adenocarcinoma SK-BR-3, human glioblastoma U-87 MG, and rat glioma C6 cell lines. Lewis lung carcinoma (LLC) inoculated to hybrid BDF1 mice was used as a model to demonstrate the delivery of FMN to the tumor. UCNPs with a core/shell structure [NaYF4:Yb3+, Tm3+/NaYF4] were used for photoactivation of FMN in vivo. PDT based on FMN, UCNPs and laser radiation 975 nm (IR) was performed on mouse xenografts of human breast adenocarcinoma SKBR-3.
Results: We were able to show that FMN could act as an effective in vitro photosensitizer for SK-BR-3, U-87 MG, and C6 cell lines. FMN IC50 values for glioma cells were ~30 μM, and for SK-BR-3 cell line ~50 μM (24 h incubation, irradiation 4.2 J/cm2). In the LLC model, the appropriate concentration of FMN (30 μM and above) can be achieved in the tumor as a result of systemic administration of FMN (at 2 and 24 hours after injection). The effect of PDT using near IR light for UCNP-mediated excitation of FMN was demonstrated in mouse xenografts SKBR-3, with the tumor growth inhibition of 90±5%.
Conclusion: The study has demonstrated the possibility to use riboflavin (vitamin B2) as a photosensitizer for PDT. The photoexcitation of FMN via the anti-Stokes photoluminescence of UCNPs allows for implementation of the PDT technique with the near IR spectral range.
Prognostic value of lung ultrasonography after on-pump cardiac surgery
Rationale: Along with bedside plain chest radiography, lung ultrasonography is being increasingly used for detection of postoperative respiratory complications.
Aim: Our study was aimed at the evaluation of lung ultrasonography efficacy for the diagnosis of postoperative respiratory complications in patients after the on-pump cardiac surgery.
Materials and methods: The study included 39 patients who had undergone elective cardiac on-pump surgery. Assessment of hemodynamic parameters and blood gases was done at admittance to the intensive care unit (ICU), as well as at 6 and 24 hours after surgery. Lung ultrasonography was also performed including counting of B-lines in 12 lung quadrants at 6 and 24 hours after surgery, as well as chest radiography at 24 hours. Duration of mechanical ventilation, time in ICU and in-hospital stay were also evaluated.
Results: Gas exchange deterioration was associated with increased numbers of B-lines: 9 (5 to 15) at 24 hours after surgery. In the patients with PaO2/FiO2 above 300 mm Hg the number of B-lines at 24 hours after surgery was 4 (2 to 8) (р = 0.04). Plain chest radiography at 24 hours after surgery revealed abnormalities in 69% of the patients. Discoid atelectases were the most common findings (n = 13). The ROC analysis showed that increased numbers of B-lines above 10 at 6 hours after completion of the surgery was predictive of the development of X-ray abnormalities at 24 hours (AUC 0.82, р = 0.02, sensitivity 86%, specificity 76%). At 6 hours after the intervention the patients who subsequently required prolonged mechanical ventilation had increased numbers of B-lines (15 [14–27]) compared to those who could be extubated within the first 24 hours after surgery (10 [3–13], p = 0.02).
Conclusion: Lung ultrasonography monitoring accelerates the diagnosis of respiratory problems after cardiac surgery and allows timely identification of the patients requiring prolonged respiratory support and ICU stay.
Is the microvasculature tone increasing with arterial hypertension?
Rationale: An increase in vascular tone is believed to be a major factor leading to arterial hypertension (AH). There are no means for a direct measurement of the vascular tone in clinical practice. Perfusion assessment by laser Doppler flowmetry (LDF) allows for an indirect evaluation of the vascular tone of the microcirculation system. Perfusion is assessed by the change in blood flow per unit of time in the given area. Therefore, this parameter should be inversely correlated with vascular tone. Aim: To compare the forearm skin perfusion measured by LDF in patients with AH and healthy volunteers with normal blood pressure, and to review the feasibility of this parameter for the assessment of the microvasculature tone.
Materials and methods: The study was carried out in two groups: group one, patients with AH (n = 43; age 62 [57; 71] years), and group 2, healthy volunteers without AH (n = 62; age 28 [24; 37] years). The perfusion in the forearm skin was measured by LDF for 2 minutes without any functional tests. "Baseline perfusion" for each subject was calculated as the average perfusion rate in a representative portion of the microcirculatory curve.
Results: Median of basic perfusion in the forearm skin in the patients with AH is significantly higher than that in the normotensive individuals: 4.88 [2.87; 8.98] PU and 3.41 [2.47; 4.99] PU, respectively (p = 0.013). The interquartile range of the baseline perfusion in the control group was chosen as provisional threshold values for the "normal" perfusion level. In 39.5% of patients with AH, their basic perfusion was within the "normal level"; 46.5% of the patients had the baseline perfusion above the "normal level", which might be due to reduced tone of the peripheral vessels. Only 14.0% of the patients had a decreased level of the basic perfusion.
Conclusion: An increase in the skin perfusion in some patients with AH may indicate a decrease in their peripheral vascular tone, which could be a potential compensatory reaction in response to the rise in blood pressure. The results obtained could have been influenced by the age-related changes in the cardiovascular system, drug therapy, etc. Further studies into the specifics of peripheral vasculature seem reasonable. They can contribute to the understanding of the pathophysiology of AH in a given patient and, in future, could be used to guide a personalized choice of therapy.
Changes in the morphology of erythrocytes after in vitro exposure of blood to carbon monoxide
Background: One of the pathological effects of carbon monoxide (CO) on blood is the formation of carboxyhemoglobin. Carboxyhemoglobin completely blocks oxygen transfer; therefore, there is a net decrease in oxygen transport by red blood cells potentially resulting in tissue hypoxia. The effects of CO on blood can also damage cell membranes. Atomic force microscopy (AFM) has been recognized as effective for investigation into the mechanisms of structural damage in erythrocyte membranes. Aim: By means of AFM, to identify characteristics of changes in morphology and aggregation of erythrocytes exposed to CO in vitro.
Materials and methods: All experiments were performed in vitro. We studied the morphology of erythrocytes and their aggregates with AFM. Blood sampling (150 μl) in microvettes with EDTA (Sarstedt AG & Co., Germany) was carried out during a prophylactic work-up of 5 volunteers. To obtain CO in a test tube, formic acid was mixed with sulfuric acid 1:1. Blood levels of carboxyhemoglobin were measured by spectrophotometry. A nonlinear fitting method of the experimental spectra was used to calculate the concentrations of hemoglobin derivatives in blood. Statistical analysis was done with the Origin software (OriginLab Corporation, Northampton, MA, USA).
Results: After CO exposure, a shift in peaks was observed. At exposure time t₂=320 s, the percentage of carboxyhemoglobin (CHbCO) was 88±2%. As a result of blood exposure to CO, at t₁=160 s 10% of the cells differed in their shape from discocytes, whereas at t₂=320 s their proportion was 38%. With increasing duration of exposure to CO, erythrocyte aggregation occurred with formation of their large conglomerates up to 30 μm in size. In the control smear, the proportion of discocytes was 96±2%, and the remaining 4±1% of the cells had the form of echinocytes. The cell diameter (Dcont) was in the range 7.5±0.8 μm. After blood exposure to CO at t₁=160 s in the monolayer, 28±5% of cells had a diameter less than<5.7 μm. After CO exposure at t₂=320 s, the proportion of cells with a diameter of less than<5.7 μm increased to 72±11%.
Conclusion: The experiments have shown that blood exposure to CO changed the morphology of erythrocytes. The formation of interconnected structures made of red blood cells was observed. With increased time of exposure, erythrocytes demonstrated aggregation with conglomerate formation.


text:
The College of Arts and Science (CAS) and the Graduate School of Arts and Science (GSAS) offer NYU students the opportunity to earn both the Bachelor's degree and a Master's degree in a shorter period of time than is normally the case. Current CAS students interested in the Accelerated Bachelor's/Master's Program (BA/MA program) typically apply during their junior year. In the graduate portion of the program, they can qualify for a scholarship covering up to 50 percent of the tuition for the master's degree.
Students in CAS and Global Liberal Studies (GLS) may apply to the program once they have completed a minimum of 48 credits toward the bachelor's degree, but not more than 96 credits, and prior to their final two semesters. To be eligible, students must have at least a 3.5 cumulative GPA and a minimum of two semesters remaining in CAS or GLS during which they are still working towards completion of undergraduate requirements (e.g., MAP, major, minor, and/or minimum credit requirements). The History department requires that you have a 3.5 college and history GPA to be admitted to the program and that you maintain a 3.5 college and history GPA to remain in the BA/MA program. A GPA above this minimum does not guarantee admission to a BA/MA program in history.
For more information, please visit the Accerlerated Bachelor's-Master's website.


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What iron does everyone use. I'm looking for new one.
No announcement yet.
new posts
Re: Irons
I have an Oliso and I loooove it. It has the auto lift feature on it (which can be disabled depending on what you are doing) they can be pricey but I had a coupon and splurged a bit. I noticed a huge difference in the outcome of my pressing immediately.
Re: Irons
I have Panasonic NI-WL600 - Cordless 360° Freestyle Steam/Dry Iron with Curved Stainless Steel Soleplate - Overview
But looking forward to the oliso pro feedback...Mary
SW Missouri
Re: Irons
I have two Black and Decker irons. An old one I use for ironing interfacing. And new slightly heavier one for quilting. I like them both and I just got the heavier one for $16 at Ross.
My sister-in-law uses a Rowenta and loves hers.
Re: Irons
Don't get a cheapie from the dollar store..(forgot the brand) I use it so much, the other night it got super hot, scorched my quilt top and then burned out. You get what you pay for!"She who dies with the most fabric wins"
Ecclesiastes 9:10 "Whatever your hand finds to do, do it with all your might, for in the realm of the dead, where you are going, there is neither working nor planning nor knowledge nor wisdom."
Re: Irons
I have a Rival that was a wedding present almost 17 years ago. I like it but would love to get the Oliso Auto Lift Pro Zone Iron. Maybe some day. My mom still uses my grandma's which is nice and heavy and presses well. I agree, for sure do not get a really cheap iron. The old saying is true, you get what you pay for.
Re: Irons
I've had a Rowenta for quite a while and love using it when I HAVE to iron LOL I just started piecing my first quilt and it's been awesome for that, too. The Oliso is intriguing to me but it will be a very long time before I would think about splurging for it. If you decide to go for a Rowenta, make sure you get one made in Germany and not Mexico . . . there is a difference.Renee
Be kind. For everyone you meet is fighting a hard battle ~ Plato:)
Re: Irons
Last year I did a little research into irons and, at the time, was disappointed in reviews on newer Rowentas and Olisos for the prices. I had just started quilting and it was hard to justify the price if I didn't continue. I bought the Black & Decker® Digital Advantage™ Iron and have been so very pleased with it. It's relatively inexpensive and reviews at the time anyway were excellent. You can check reviews on almost any iron at Bed Bath and Beyond or Amazon. I bought mine at BBB because they always have a 20% coupon available.
Re: Irons
I have to admit it, but I use inexpensive .....read cheap....irons... I have small hands, so the smaller irons are usually just right for me. However... I might consider a slightly better iron.... If convinced that it really is worth the money.... Nothing really expensive, but better than what I always buy,...
Sandy from Cincinnati
AKA Kermit
Re: Irons
I love an iron that gets very hot, but is light weight. (Remember, it is heat, not weight that gets the job done for quilters. So save yourself some carpal tunnel issues down the line and ditch the heavy iron for a HOT one.) I have had two Black & Decker irons in the past that I loved - got very hot, but were not at all heavy. But a few years ago, hubby got me a Rowenta for Christmas. A great iron that gets quite hot, but it is a heavy iron. So when it finally goes, I will go back to the B&D irons.Courage is being scared to death, and saddling up anyway. ~John Wayne
Quilting is my passion . . . chocolate is a close second!
Re: Irons
I had an expensive Rowenta ($130) and it started leaking like a sieve after a year. I threw it out and bought the Oliso with auto-lift (the blue one, not the more expensive yellow one) at Joann's on Black Friday for $59.00. I LOVE LOVE LOVE the Oliso. It gets plenty hot, steams better than the Rowenta without leaking, and I've gotten spoiled by the auto lift feature.Joan, aka the Unaquilter
"I've never been to heaven, but I've been to Oklahoma."
Learn more about me and my quilts at my blog:
Re: Irons
I have a Rowena ......it's 3 yrs old, I love mine.Jacqueline ( Sugar ) Dorer-Russell
"I miss the me I was when you were here"
Re: Irons
I got the Olisio for Christmas. Would never have paid that much for an iron, bur it was on sale at Joanns, and then I had a Hancocks coupon that they also took ( and I don't think should have). Bottom line it was far less than half the regular price. I do like it, seams are much flatter with less effort. So far so good!
Re: Irons
Right before Christmas, My Rowenta that I had bought from Sams over a decade ago, SPIT brownish stuff all over the white area of a red and white holiday quilt I was making! That was enough of thaT! I've been wanting a really good iron for a while, so I ordered a couple of pricier Rowenta's from Amazon, didn't like them for one reason or another, so I ended up ordering the Rowenta with the separate water tank and I'm been very very very happy with it. The first time I pressed on the steam button, it about kicked itself out my hand. I then proceeded to iron everything in sight that night! (I had to tell my husband that his neatly ironed sheets and boxer shorts were a one time thing and not to get any ideas!)
The big difference I see in this iron is the stainless steel soleplate. It tends to glide over the material instead of grabbing it and stretching it. Even one of the Rowenta's that I sent back had some kind of "titanium" type plate. It did not glide like the stainless steel. And the other thing is the number of steam holes. This one is covered in holes.
Granted, it's pricey and I would never have bought a few years back……Now i hope it lasts long enough to justify the expense!


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My fondest memory of the Mass Effect series is a conversation I had with Thane Krios. In a quiet corner of the Normandy's Crew Quarters he explained that his species, the Drell, believe their souls exist as separate entities from their physical bodies. For Thane, this belief allowed him to reconcile his nature as a virtuous figure with his profession as an assassin for hire; the deplorable actions of his body could not tarnish the purity of his soul. The Mass Effect series is about intergalactic politicking, mediating interspecies relationships, navigating moral dilemmas, and--of course--engaging in warfare. But it's the moments in which characters reveal something deeply personal about themselves that are the most profound.
I've always been fascinated with the series' depictions of religion, the way it leans on frameworks of faith that have parallels in real life but then creates a layer of abstraction by exploring them through alien species or relating them to existence on an intergalactic scale. These are the moments that stick with me, and in my hands-on with Mass Effect: Andromeda, it was a moment like this that I walked away thinking about the most.
Andromeda follows thousands of people from numerous species as they venture from the Milky Way galaxy to a distant world in search of a new home. For these characters, and the player, Andromeda is positioned as a journey of exploration and discovery. From a broader gameplay perspective, it's the discovery of new planets to adventure in, quest threads to follow, decisions to make, and conflicts to resolve--either through diplomacy or violence. But the theme of discovery also drives the narrative arcs of Andromeda's cast, all of whom are hoping to find something beyond a new home.
Aboard the Tempest--the ship that players will use to travel around Andromeda's Helius Cluster--I encountered one such person: Suvi. She's staring out into the the depths of space and admiring the view. To her, the distant stars and majestic planetary bodies are "a constant reminder of the divine intelligence behind all of creation."
Like Thane, Suvi reconciles two parts of her that, to outsiders, seem contradictory: she's a woman of science, but also of faith. During our conversation she reveals science brings her closer to something greater than herself. She's lived her life having to justify these beliefs and needing to prove that her faith in the divine doesn't diminish her work as a scientist.
As a person from a traditionalist Muslim family that has grown up in Western society, I couldn't help but relate to Suvi. That perceived incompatibility between faith and science has been mirrored in my own life, and Suvi expressed an idea that I've held but never been able to adequately verbalize. In that moment, I found myself remembering why I love the Mass Effect series and why I find Andromeda's potential so exciting.
After this exchange, I took the time to wander around the Tempest and speak to more of the crew joining protagonist Ryder in the search for a new "Golden World." In the engine room Gil questioned his decision to join the Andromeda Initiative but said he ultimately did so to find a purpose for himself. Similarly, Vetra, a well-connected Turian that specialises in gathering information, felt the need to justify her presence on the mission, indicating that she's dealing with issues of inadequacy and self-confidence. Jaal, who is part of the new Angara race native to the Andromeda galaxy, is an outsider trying to find footing among people from unfamiliar cultures. PeeBee, the wise-cracking Asari, refused to entertain any personal questions and outright said she has no interest in putting down roots or finding a new family in the crew of the Tempest. She bounced between happy-go-lucky, guarded, and distant.
For me, the series' strength lies in textured, layered characters offering unique perspectives that I can learn to understand--and perhaps even relate to. Based on the few hours I spent with Andromeda, it looks like there will be an abundance of them.
Beyond the promising characters, Andromeda looks to have made a number of interesting changes to the familiar Mass Effect framework, the majority of which I was able to experience in the game's opening missions. Don't worry, there won't be any spoilers ahead.
Our search for a Golden Planet began aboard Hyperion, an Ark housing a human colony numbering 20,000 people. Player-character Ryder is awoken from cryosleep 600 years after departing from the Milky Way galaxy. As Ryder was getting her bearings, a doctor approached and gave me my first taste of the new dialogue system, which looks to address the binary nature of the series' role-playing.
It does this by asking players to select responses based on tone. In any given conversation you're presented with the option to be casual, emotional, logical, or professional, depending on the scenario. Instead of having a series of neutral probing questions and then two responses that align with either the Paragon or Renegade moral archetype, responses now represent a diverse set of emotions that shape each relationship dynamic.
For example, Cora Harper is the Pathfinder's second in command and technically Ryder's superior. When I later became the Pathfinder (despite the fact that she was better suited for the role), some tension began to grow between us. This informed the way I conducted myself around her; I opted to remain professional to prove that I was capable of handling the responsibility. For PeeBee, however, I adopted a casual tone in conversation, purely because she came across as someone that prefers to be around a leader that isn't uptight all the time.
As a result, Andromeda doesn't feel like it's funneling you down a path of good or evil. Instead, the different flavors of responses invite us to play different roles with different people and define relationships with greater nuance.
Ryder's first mission takes me to Habitat 7, a planet set to be the new Earth. However, upon my arrival it became abundantly clear that it was less than golden. In fact, Habitat 7 looked like it had been torn and twisted into something uninhabitable.
It's blue sky and sparse plant life indicated that it could have once been a new home for mankind, but it was now fraught with thunderstorms, and oxygen levels had plummeted as the atmosphere became choked in argon nitrogen. Intense magnetic activity meant that rock formations were floating in the air, and metallic inclusions attracted destructive electrical phenomena, the danger of which I experienced first-hand when a lightning bolt hit our ship and scattered my crew around the designated landing point. With only security specialist Liam Costa in tow, I began searching for the rest of the team.
The different flavors of responses invite us to play different roles with different people and define relationships with greater nuance.
Taking a page of out of Dragon Age: Inquisition's book, Mass Effect: Andromeda's planets are built to be a series of contained spaces where players explore and complete quests. Although they're not connected to form what we'd traditionally consider an open-world, each location is large enough to hold story missions, as well as side missions you can uncover and complete by venturing off the prescribed path and exploring.
To accommodate this, Ryder has been given a robust set of traversal abilities, most notably a jump and a dash enabled by a rocket pack. Ryder was also able to clamber up Habitat 7's rocky cliff faces to reach elevated areas, a skill that proved necessary to track a distress call from a teammate for a sidequest.
These abilities are also at the core of Andromeda's new combat mechanics, which I employed against the aforementioned Kett. At one point we came upon a friend who had been cornered by this unfamiliar alien race. Wearing armour made of bone and brandishing guns, they looked to be hostile but, as pointed out by Ryder, first contact protocols dictate that you cannot open fire unless fired on. Given the option to act first and talk later, I decided to let cooler heads prevail and attempted to talk to the Kett. Since they spoke an unknown language and weren't treating our friend very nicely, I had no option but to engage.
Interestingly, Ryder voiced her displeasure about how things unfolded and even made the case for the Kett feeling as threatened by us as we were by them. Andromeda makes attempts at presenting the Kett, and the mysterious Archon leading them, as figures that could also be on a journey that parallels ours. Since the portions of the game we played were devoid of necessary context, it wasn't clear what their motivations were, but I got the feeling the game doesn't want to present them as clear-cut bad guys.
In this scenario it was us versus them; the perfect opportunity to put combat through its paces. Mass Effect 3's combat serves as the foundation for the way Andromeda plays, in particular the increased freedom of movement. However, one major difference is that the role of cover has been significantly diminished. Although Ryder will automatically move into cover as you approach any appropriately large, solid object--and in fact it's often necessary to recover from damage--but between the new movement abilities, Biotic powers, and destructive weaponry, Ryder feels like a character designed to always be on the offensive.
The Kett didn't make a habit of coming out into the open, preferring to obscure themselves behind cover and quickly move between objects in the environment. As a result, I was forced to take the fight to them by leaping out of cover and launching myself into the air with a jet pack. Once airborne, I could hover long enough to aim and fire off a few shots. Ryder's dash could then be used to quickly maneuver back into cover and begin the loop again.
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While combat in previous entries in the series felt very stop-and-start--with players moving between different cover points and popping out to fire their weapons or use powers--Andromeda's skirmishes feel like they're focused on forward momentum. However, the combat's newfound energy comes at the cost of a degree of control and a layer of strategy that series fans are used to having.
Unlike previous games, you only have direct control over Ryder, and teammates can't be issued commands beyond moving to a specified location or focusing fire on a designated enemy. BioWare has also reworked how Biotic powers are implemented to ensure you aren't spending extended time in a radial wheel. Instead of having a suite of powers on an instantly accessible wheel, you have three favourites that are assigned to shortcuts so that they can quickly be employed in the heat of battle, much like in Mass Effect 3. It is possible to create four loadouts that you can switch between during battle, but given that they're two menus deep, it only makes sense to do this in order to adapt to changing battle conditions between waves, rather than as a workaround for the new system.
Another major change for Andromeda is the new freeform class system. Instead of selecting a specific role and developing a set of abilities limited to that class, you're able to learn any ability and even reassign Ryder's skill points at any time. This is a welcome change as it allows you to create unique play styles and experiment with ability combinations. Those that opt to specialise when acquiring and upgrading abilities will unlock Profiles that correspond to classes from previous games. These are used to enhance abilities by bestowing Ryder with stat bonuses. Together these changes empower the player to have greater control over the type of Ryder they develop and guide through the galaxy.
After the delays and relatively little we'd heard about Mass Effect: Andromeda, I began to worry that it may not live up to the series' legacy. And while I can't outright say I'm confident it will deliver, Andromeda's tweaks to combat and dialogue are smart. However, my passion for the Mass Effect series is tied to the connections I developed with its characters. So in the end, that personal moment with Suvi is what makes me optimistic about the series' future.
The products discussed here were independently chosen by our editors. GameSpot may get a share of the revenue if you buy anything featured on our site.


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In the Interlude, which is told from the first person point of view of Hoa, Hoa describes himself as being powerful and feared among his kind. He explains that other stone eaters are slowly encroaching on the egg that is Castrima but that he has been killing the ones he considers enemies. These enemies have told Hoa about another ancient stone eater who would kill Essun if he could because Essun plans to finish what Alabaster started. Hoa insinuates that this stone eater has found allies up north to help him with his plan to make Essun destroy herself. Hoa closes the interlude with his hope that one day Essun will forgive him for what he has to do.
Chapter 14 returns to the second person point of view. One day, three hunters are killed topside in an ambush. When two hunters go...
(read more from the Interlude - Chapter 15 Summary)
This section contains 2,003 words
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The Federal Trade Commission (FTC) has finalized the latest version of the Guides for the Use of Environmental Marketing Claims (Green Guides). Effective October 11, 2012, the Green Guides provide marketers with insight regarding when environmental marketing claims are unfair or deceptive and therefore subject to enforcement under Section 5 of the Federal Trade Commission Act (FTC Act), 15 U.S.C. 45. With the new Green Guides, the FTC is aiming to strengthen, add specificity to, and enhance the FTC's guidance on making general environmental benefit claims.
Purpose of the Green Guides and the FTC Enforcement Strategy
The FTC first promulgated the Green Guides in 1992 as a means of helping marketers and businesses avoid making environmental marketing claims that are unfair or deceptive under Section 5 of the Federal Trade Commission Act ("FTC Act"), 15 U.S.C. 45. While the Green Guides are administrative interpretations of the law and are not independently enforceable, the FTC will likely use the Green Guides as a set of standards to inform what is considered unfair or deceptive marketing and therefore subject to enforcement. The Green Guides address claims about the environmental attributes of a product, package, or service in connection with the marketing, offering for sale, or sale of such item or service to individuals. In the new Green Guides, the FTC has made clear that its guidance is also applicable to claims made during "business-to-business" transactions.
In a 2009 congressional hearing, James A. Kohm, Associate Director of the Enforcement Division in the Bureau of Consumer Protection at the FTC, declared that the latest revisions of the Green Guides would be the first step in the Commission's "multi-tiered approach" to combat what he referred to as a "tsunami of environmental marketing" that developed over the past decade. According Associate Director Kohm's prepared statement, the Commission planned on first, promulgating new rules and guides to make the "rules of the road" clear for businesses; second, directly challenging fraudulent and deceptive advertising through enforcement actions; and third, by informing consumers.
The 2012 Revision of the Green Guides
The new Green Guides include guidance on a number of specific claims that could be made by marketers. Some claims addressed in the new Green Guides simply were not as prevalent when the guidance was last revised in 1998, such as claims related to carbon offsets, claims made regarding renewable energy, and sustainable or organic / natural claims.


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"Our school does not teach journalism. We just advise the yearbook" Too often we hear these words when talking to advisers about the work they do with their students to produce a yearbook. As yearbook professionals we are here to tell you, no matter the format of your yearbook, the work of journalists boils down […]
Tag Archives: journalism
Yearbook is a form of Journalism
Posted in Yearbooks Blog Also tagged narrative, objectives, Yearbook Comments closed


text: There are some fundamental questions I need answers too in regards to how a character/person functions. Currently I'm running off the id (instinct you're born with), super-ego (internalized parent), and ego (the result of the conflict between id, and super ego; or the one who makes the decisions)model; however i'm struggling to figure out which part of the mind is responsible for caring about another person. Do we care only for those who increase our chances of survival? Or for those that provide a chance for us to pass on our genetic code? Why would I feel sadness if someone I was close to died? Why would i feel anger if someone i was close to got hurt? Some would probably answer "empathy", in which case i'd ask : where does empathy come from? is it in-built? or is it learned? What part of the mind is responsible, and how does it come to be?


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A look at some of the most important figures surrounding the team in STATS +, Presented by The New York Lottery
Through the first four games of the season, Evan Engram leads all rookie tight ends with 19 receptions. The first-round pick is also first in receiving yards (200) and receiving first downs (10).
Through Week 4, Eli Manning ranks first in the NFL in fourth-quarter passing yards with 454. He also leads the league with 116 total completions.
Odell Beckham Jr. is the Giants' all-time leader in receiving yards per game against AFC opponents with 122.5 over 11 games.
Since 2000, the Giants have a winning percentage of .657 (44-23) in the month of October. They are 32-28 (.533) in September, 29-39 (.426) in November, and 41-40 (.506) in December/January in the regular season.
Through the first four weeks of the season, NFL rookies have accumulated 5,835 yards from scrimmage and 43 touchdowns, both of which are the most by rookies through Week 4 since 1970. Last week, rookie running back Wayne Gallman, the Giants' fourth-round draft pick, recorded 50 yards from scrimmage and a touchdown catch in his NFL debut.


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Rapidly evolving GIS technology has many applications directly related to engineering, surveying, land planning and geotechnical sciences, and as such offers our clients new possibilities for visualizing and analyzing spatial data. From our first major GIS project in 2008, we have rapidly expanded our capabilities. Utilizing state-of-the-art Trimble High Accuracy GIS-grade GPS equipment, we can provide up to four field crews for data collection by foot, ATV, or 4WD vehicle. Our field crews have considerable expertise with both TerraSync and CartoPac GIS mapping software, enabling us to capture point, line, and polygon features in an adept and cost-effective manner.
Efficient field collection begins with project research and planning. Summit's unique expertise with a wide array of available GIS base data gives us the ability to develop effective project planning to ensure smooth, expedient field operations. Using Trimble Pathfinder Office software, custom data dictionaries are created and tailored for the specific requirements of the project. In the office, Summit's GIS work is processed using industry-standard ESRI ArcGIS software. The geodatabase format enables large amounts of both raster and vector spatial data to be incorporated into a single highly organized database. Deliverables to the client can range from individual shapefiles transmittable by e-mail to an entire geodatabase delivered on a portable hard drive. Our GIS staff can also produce in-house hard-copy map books and generate exhibition-quality large format maps, mounted and ready to display.
Looking to future applications of GIS technology, Summit has become involved with RS 2477 mapping services. Our savvy for historical records research, cadastral survey procedures and aerial photo interpretation, along with our ability to georeference and reconcile historical maps with modern imagery, provides us with the background needed to perform verification as to whether or not an existing road meets the requirements for a public right-of-way under U.S. Law RS-2477. This is an issue of ever-increasing importance in the American West, and Summit stands ready to provide the research, mapping, documentation and reporting required for making appropriate evidence-based determinations.
If we can add value to your next project, please contact Summit Engineering at (775) 747-8550 in Reno or (775) 738-8058 in Elko. We welcome the opportunity to work with you and your team.


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Department for Education written question – answered on 4 June 2018.
To ask the Secretary of State for Education, what assessment he has made of the reasons for the increase in the number of school start deferral requests for summer-born children between 2015 and 2017.
The Department recently published a research report on delayed school admissions for summer born pupils, available here: https://www.gov.uk/government/publications/summer-born-children-school-admission.
The report includes the findings of a survey of local authorities. The findings show that there has recently been an 84% increase in the number of requests for summer born children to be admitted to reception, rather than year one, at the age of five. Such requests represent 0.5% of the five-year-old population, and 75% were granted.
The findings also show that there are fewer requests made in areas where the local authority's policy is only to grant requests supported by strong evidence, and there are more requests in areas with a higher proportion of granted requests. The report suggests this may be because parents are more likely to submit a request if they believe there is a higher chance of it being granted. The increase in requests may also be due, in part, to greater awareness of this option amongst parents. The Department remains committed to amending the School Admissions Code to ensure summer born children can be admitted to reception at age five where this is what their parents want.
Yes10 people think so
No2 people think not
Would you like to ask a question like this yourself? Use our Freedom of Information site.


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text: Stop by the Museum tomorrow for Weaver First Saturday Free for All and enjoy a fun, family day at the Museum… for free! Come view the newly opened exhibition, Archipenko: A Modern Legacy. Stay for brunch and live music from Jesse Montoya. Make sure to take a Florida-winter stroll through the Gardens that are still lush and green! Whether you chose to spend your time at the Museum or around town, have a wonderful weekend.


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Getafe 1-0 Barça: First league defeat | FC Barcelona
Barcelona suffered their first league defeat of 2020-21 against Getafe on Saturday, going down 1-0 to a Jaime Mata penalty at the Coliseum Alfonso Perez.
Griezmann didn't respond despite being handed Barça's No.9 role | Sport
Antoine Griezmann was handed the No. 9 role against Getafe but failed to perform and will need to prove himself to stay in the team in the coming weeks.
Barcelona expect Lionel Messi to complete Man City transfer next summer | Mirror
Barcelona currently expect Lionel Messi to leave next summer when his contract expires and move to Premier League side Manchester City.
Nyom to Ansu Fati: "18 years old and you're diving like that?" | AS
Allan Nyom raged at Ansu Fati during the 1-0 win. He stood over the 17-year-old (!) after tangling with him and shouted: "18 years old and you're diving like that? 18 years old!?"
Koeman after Getafe loss: "I don't like to talk about referees" | AS
Ronald Koeman didn't want to talk about referees after Barcelona lost to Getafe but did take time out to have a pop at Nyom for comments he said he's made during the match.
Bordalás: "I doubt very much that Nyom insulted Koeman" | Mundo Deportivo
Getafe boss Jose Bordalas has responded to Ronald Koeman's post-match comments and says he doubts that Allan Nyom insulted the Barcelona coach.
Riqui Puig and Braithwaite played again three months later | Sport
Saturday's defeat to Getafe saw Riqui Puig and Martin Braithwaite both make their first appearances for Barca since featuring against Alaves in July.


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SKYLOTEC introduces the SKYSAFE PRO FLEX Energy-Absorbing Lanyard series. These lanyards are designed to provide protection in 6 AND 12 foot free fall in a single lanyard. The SKYSAFE PRO FLEX also includes rescue web loops integrated in each leg for a strong and effective means of rescue. This lanyard also features a variety of ANSI tested hook configurations including lightweight aluminum alloy hooks or carabiners to meet your demands.
SKYLOTEC, www.skylotec.com, 303-544-2120


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Out of the Space of Reasons: Argumentation, agents, and persons
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- Source: Pragmatics & Cognition, Volume 19, Issue 3, Jan 2011, p. 383 - 398
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The paper investigates the 'logical space of reasons' as a social space in which rational agents operate and persons in an important sense come to be. Building from an investigation of argumentative agents in Aristotle's Rhetoric, I discuss both interior and exterior criteria for personhood and propose that the latter shows how argumentation, as a principal activity of the space of reasons, results in the particular kinds of persons we recognize there as rational agents. The overall analysis is indebted to Robert Brandom's centralizing of the practice of giving and receiving reasons and the suggestive ways this can be applied to the realm of argumentation.
© 2011 John Benjamins Publishing Company


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More than 1,300 students boarded buses on Sunday for the 24-hour trip to Miami.
It took 26 buses to hold them all.
The Huskies are the first team from the Mid-American conference to play in a BCS bowl game.
NIU is a double-digit underdog to the Florida State Seminoles, but the students aren't buying the predictions.
"I think we're gonna have that underdog advantage going in and we're gonna have a good fan base as you can see, we're gonna be getting loud," said NIU student Kyle Dockstader.
"We're gonna shut 'em out the entire game," NIU student Roy Williams said. "It's gonna be a great time and then we're gonna celebrate New Year's in Miami."
ABC7's Rafer Weigel is heading south too and will have reports from south Florida starting Monday.


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Tuscany Walnut Tumbled Travertine tile is rich and dynamic with shades of browns, taupes, tans and creams and is backed with mesh for easy installation. This beautiful tile creates a stunning travertine backsplash, shower surround, or a variety of other architectural features.
Item Description: Tuscany Walnut 2×2 Tumbled In 12×12 Mesh
Item ID: SMOT-TW-2X2-T
Collection: Tuscany Walnut
Primary Color(s) : Brown
Material Type: Travertine
Country: Turkey
Size : 2×2
Available Finishes: Tumbled
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Humble Pie à La Mode
When you go hiking up a mountain with your fit husband and fit daughter and find that, between the altitude and the steep grade, you can't keep up with them, even though it's a hike you've done before, you eat a little humble pie. Then, when your boot slips on some rocks on the way back down and you fall and bruise your tailbone, you eat a big slice of humble pie. You see by the solicitous looks on their faces that you have in fact aged while you were not paying attention, and maybe you should stick to activities more suited to your abilities. It's a day for humble pie a la mode.
I must admit that I am surprised by physical limitations. I am used to feeling in control, at the top of my game, the super mom who can handle anything life proposes. Curtailing a hike due to waves of nausea and a pounding heart, and ending it clumsily on my butt, are not the kinds of events that jive with my self-image. And facing my shortcomings is not my idea of a pleasant morning.
The taste of that humble pie, however, is a good reminder for me that I am not in charge, and that I have never been in charge. God is. My ego likes to think differently, but as Jesus reminds us, in the Gospel of Matthew, "For mortals it is impossible, but for God all things are possible." (Mt. 19:26) I need this reminder on a daily basis. If my career as a super mom has been entirely due to the presence of God, my growing older is also happening by the grace of God. My best moments have always occurred when I have relied on God rather than on my inflated image of myself.
I may yet try that hike again, after I tackle some smaller hikes, and if I get back into the shape that permits long, steep climbs up a mountain. But I will do it with clear-eyed gratitude: for legs that can walk and lungs that can breathe and a heart that intuits that everything I do is thanks to a good and gracious God. Sometimes pie is good for me.


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Crafted from premium microfiber vegan leather, this envelope purse comes in an elegant quilted design and a magnetic metal buckle. Designed by Fae, this piece can be worn as a crossbody or shoulder bag and can be carried around like a clutch. Featuring divided panels and zippered pockets, organizing your valuables is easy in this piece.
L 19cm x H 14cm x D 7cm
For light cleaning: wipe with a damp cloth
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Hand wash with cold water and hang to dry or dry clean
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Kiswa from the times of Ottoman empire big draw at book fair
Abu Dhabi: A Ka'aba cover from the time of the longest reigning Ottoman emperor nearly 500 years ago was the highlight of the 23rd Abu Dhabi International Book Fair (ADIBF 2013) that concluded this week.
Known to be the world's oldest known Ka'aba cover on public display, it was said to have been sent to Makkah by Sulaiman the Magnificent nearly 500 years ago. Also called a Kiswah, the artistically embroidered fabric ceremonially covers the Ka'aba before the Haj and was brought to ADIBF 2013 by Austrian company INLIBERS who handle preservation of ancient manuscripts and exhibits.
Rare Kiswah
According to the firm's owner, Hugo Wetscherek, there is no earlier recorded example of a Kiswah. "Our Kiswah is the same in every iconographic detail with a counterpart that can be found at Topkapi Palace in Istanbul. Both the name of Sultan Sulaiman and the year 950 in the Islamic calendar are stated in the splendid calligraphy and the date is confirmed by carbon dating technology", he said.
It is seen as the highest honour bestowed on any Muslim head of state to provide the cover for the Ka'aba.
ADIBF is the only place where this exhibit has been displayed to the public.


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The Finnish industrial conglomerate MSK Group has acquired the entire share capital of Matec GmbH, a cabin manufacturer operating in Germany and Slovakia. With the acquisition, Matec's plants in Döbeln and Lipany become part of MSK Group. Matec manufactures cabins for machinery of many familiar brands, such as Manitowoc, Volvo CE, Liebherr, Komatsu and Cargotec.
The acquisition is part of MSK Group's strategy with which the group takes a confident step toward its goal of being the leading system supplier of safety cabins for mobile machinery in Europe.
"The acquisition is a significant step for the company and the entire region. The Central European expansion will not replace the Finnish operations but will supplement them, further strengthening MSK Group. We will continue to handle the Nordic, Baltic and Russian markets from Finland, while Matec will concentrate on customers in Central Europe. Supplemented with the expertise of MSK Plast, particularly in manufacturing plastic parts for mobile machinery, we will be one of the largest contract manufacturers of mobile machinery in Europe," says Timo Lehtioja, President of the Group. He adds that the family business has a genuine will to develop its operations at all sites. "In accordance with our values, we want to provide our customers with exceptional quality, reliability and partnership while taking care of the well-being, safety and development of our staff."
"We are enthusiastic about the Matec's new industrial owner that is a world-class leader in cabin manufacturing. We believe that Matec can reach a new operational and turnover level as part of MSK Group," says Matec GmbH's CEOs Carsten Prilop and Stefan Thieme.
Matec's operative management will continue with their duties, reporting to MSK Group's President, Timo Lehtioja.


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By Naomi Starsiak
As a doula, it's my job to keep up on information and statistics so I can give my clients the best advice available. I manage that by using several different sources, all of which you can use too.
Evidence Based Birth – http://www.evidencebasedbirth.com This website is generally my first stop. Its mission is to turn journal articles, meta-data studies, and other medically written works into information that is easy for parents to find and understand. The articles are written by medical professionals and are reviewed every few years to make sure the most up-to-date information is included.
NYS Department of Health – https://profiles.health.ny.gov/hospital A little hard to navigate but a great way to see side by side comparisons of different hospitals in the area. This website offers breakdown by Natural Birth and C-Section and each section offer further statistics on things like episiotomies, use of forceps, inductions, and anesthesia.
American College of Gynecologists – http://www.acog.org Most of the content is restricted to members but any handout you could get at an OB/GYN's office is available for the public. This helps in contrasting the newest information available with what is actually being held up as the standard of care.
Spinning Babies – http://www.spinningbabies.com A site that talks about the body mechanics of pregnancy and birth. This site is created for pregnant moms and there are lots of videos and easy to understand articles.
I know that pregnancy tends to leave parents with a lot of things to do in a short amount of time, but if you don't want to take my word for it then carve out some time and look over these sites.
Naomi Starsiak is a birth and postpartum doula, a natural birth consultant, and the co-owner of A Peaceful Birth doula & childbirth service. You can find her on Facebook at facebook.com/APeacefulBirthDoulas.
Have a question? E-mail it to Naomi at firstname.lastname@example.com.


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Emblem of an Abstract Riot
Emblem of an Abstract Riot is a limited edition original resin sculpture.
Handcrafted by the artist and composed of solid resin. The artwork is packed in charcoal foam and protected by Uline Indestructo mailer boxes.
Preview copies of Abstract Riot were first exhibited at PiQ Products in New York City, Guzu Gallery in Austin, Texas, and shown in the April issue of Clutter Magazine.
Dimensions: 6 x 6 x 3.75 inches
Tracked Shipping & Handling
USA/Canada - Expedited Shipping $25. International - Tracked Packet $45.
Production Time: Ships in 2 weeks after order.
Customs & Duties: Artwork will be shipped well packed and marked at actual value with HS code 392640 Decorative Polyresin Figure. Extra customs & duties charges may be added by the receiving agency.
Prices are in US Dollars.
*This artwork has been held in customs in the past for further inspection due to the nature of the subject. Ships from Vancouver, Canada.


text: Sheharzad Arshad is not an ordinary person. He's known by many nicknames, mainly because of his activity as an illustrator. And, you know, it's really boring to sign your own name in a profession like that. His pictures and cartoons are rather funny. But if you can't stand black humor, you won't see any fun in them. His works are rather famous – as famous as black humor itself.


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Diana Lemberg
This interdisciplinary project provides the first archival account of how language training shaped and was shaped by U.S. international engagements from World War II through the end of the Cold War. Scholars of U.S. international history have infrequently addressed language-related issues. This is a surprising lacuna given the powerful players--the federal government; major foundations; prestigious American universities--that became invested in the creation and dissemination of linguistic expertise in the mid-twentieth century. The project tracks two of the defining language phenomena of the "American century": the rise of global English, and Washington's growing involvement in language-training initiatives both at home and abroad. By analyzing the place of language training and applied linguistics in U.S. foreign relations, the project will speak to scholars of U.S. international history, decolonization and development, and the history of the social sciences, particularly linguistics.


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Press room
New scientific publication from the GR@ACE Project
Study finds six new genetic variants related to Alzheimer's
- The prestigious journal Nature has released a scientific paper from Ace Alzheimer Center Barcelona that provides new data regarding genetics in Alzheimer's disease
- The study uses around half million genetic samples from the consortium GR@ACE, GEDESCO, IAGAP, EADB and UKBiobank
- This is the third article from the Genomic Research at Ace (GR@ACE) Project, driven by Grifols and Fundación "la Caixa", but due to the remarkable collaborations from the scientific team at Ace, the information generated in this program already appears in more than 10 international scientific papers
A study from Ace Alzheimer Center Barcelona, recently published in the prestigious Nature Communications magazine, has gathered all the known genes associated to Alzheimer's disease giving, as a result, six new genetic variants related to Alzheimer's in APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and SHARPIN genes.
In addition, the study made with the collaboration of the Amsterdam University Medical Center (VUmc) builds a polygenic risk variable that shows a difference in the disease start age between 4 and 5.5 years in patients carrying the APOE ɛ4, main disease risk factor.
Itziar de Rojas, pre-doctoral researcher in Ace Alzheimer Center Barcelona and main study author, thinks it is a step forward in "Alzheimer's early diagnosis, because the polygenic risk punctuation and the apolipoprotein ɛ4 (APOE) association gives a good tool to select patients with subjective memory complaining and mild cognitive impairment who are in high risk of developing dementia". "Furthermore", she states, "thanks to the study results, we can keep deepening in the APP gene mechanisms in order to refine the amyloid cascade, main responsible in the senile plaque formation".
To obtain these results, researchers have built an association of the complete genome from half a million Alzheimer's patients by merging the data from the national consortiums GR@ACE (Genome Research at Ace) and DEGESCO (Dementia Genetics Spanish Consortium) and internationals consortiums such as IGAP (International Genomics of Alzheimer's Project), EADB (European Alzheimer DNA Biobank) and UKBiobank.
This publication at Nature Communications is the third great article from the Genomic Research at Ace (GR@ACE) Project, but due to the Ace scientific team remarkable collaborations, the information generated within the framework of this program has been already published in more than 10 international research articles.
The study is part of De Rojas' doctoral thesis, that focus on the study of Alzheimer's genetic and molecular biomarkers. Thanks to her participation on the GR@ACE Project, the young researcher and doctoral candidate is investigating the association between Alzheimer's genome and the definition of people in risk of developing dementia with the objective to develop early diagnosis.
"The fact that GR@ACE is still leading us to extraordinary new data and knowledge is the success of the 2 premises behind the project," states Agustín Ruiz, scientific director of Ace Alzheimer Center. "First, the open-access mindset and research in collaboration will take us further and, second, the fact that non-hypothesis-driven type of research in the field of genetics was the right approach for Alzheimer's."
A priority investigation project based on genomic technologies
The GR@ACE Project has as main objectives integrative bioinformatics, personalized medicine and identification of possible new treatments.
From a clinical point of view, the impact of genomic technologies regarding diagnosis and the ability of predicting it is proving to be highly important. In fact, experts consider that genetic characterization from Alzheimer's patients will generate a change in the diagnosis model in the future.
During the GR@ACE Project first phase, a complete genome scan was made with the samples from the Ace collection that, with more than 10.000 blood extraction samples, is the largest in Europe.
GR@ACE, driven by Ace Alzheimer Center Barcelona since 5 years ago, has also the support from Grifols and Fundación "la Caixa". Besides, this project has received financial grants from competitive funds from Instituto de Salud Carlos III and Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), as well as genetic samples from the Dementia Genetics Spanish Consortium (DEGESCO).


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Sliced nectarine atop a wheat cracker gives this treat its fresh feel. And the Creamy Original, with a sprinkle of rosemary, is certain to brighten any mood.
Smear Creamy Original atop a wheat cracker. Top it off with sliced nectarine and sprinkle of rosemary for a treat that will brighten your mood.


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PORTLAND, Maine — A group of businesses, nonprofits and policymakers supporting broadband expansion have formed the Maine Broadband Coalition to research and lobby in favor of bills supporting increasing Internet speeds in Maine.
The group includes a number of organizations, companies and state officials who have previously advocated for expanding high-speed broadband and fiber-optic networks in Maine. Supporters include the Maine Office of the Public Advocate, Coastal Enterprises Inc., the t own of Islesboro, the town of Rockport, the Washington County Fiber Initiative and GrowSmart Maine.
Carla Dickstein, a senior vice president for research and policy development at Coastal Enterprises Inc., said in a news release Monday that the group "has come together very quickly" and is recruiting other supporters in a variety of business and nonprofit sectors.
Dickstein said the group has been organizing for several months in advance of the legislative session that includes about 35 bills dealing with broadband expansion in the state.
According to a website the group registered last month and launched recently at mainebroadbandcoalition.org, the coalition does not plan to raise money and does not charge dues to members.
"The only purpose of the MBC is to assemble cogent, fact-based information to help public policy makers and Maine citizens make the best choices about building a robust and productive information technology infrastructure — decisions we are all facing right now," the website states.
The group's website on Monday identified one legislative bill, LD 1063, which would require cellphone companies to pay into a state fund managed by the ConnectME Authority to expand high-speed Internet in the state and would make changes to the structure of that state agency.
That bill was introduced by Assistant House Majority Leader Sara Gideon of Freeport with co-sponsors including Republican Senate President Mike Thibodeau, Assistant Senate Majority Leader Andre Cushing and Senate Democratic Minority Leader Justin Alfond.
The newly formed coalition argues that expanding broadband in the state is a requirement for improving the state's economy.