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Though there are several options for creating fancy enterprise cards, you have to note that this shall be outlined by the nature of your business. It's free to make use of the enterprise card maker to experiment as much as you want, and then it prices just $8 to obtain the final outcome. Fast and straightforward to make use of – Create professional enterprise cards in only a few minutes. You possibly can design marvelous cards that will attraction to a variety of people and categorical your profile and portfolio to one of the best of its potential right from the consolation of your workplace or dwelling.
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Bland business playing cards are destined to get shoved into pockets and thrown away later. For those who run into any issues, our Customer Service workforce is glad to help you design the proper business card in your restaurant. You'll be able to successfully use them for making high quality and artistic business cards.
Process of designing and creating premium enterprise cards is easy with none knowledgeable support. Create your individual business card in simply few seconds, just enter your details and choose from multiple business card created. Easy to design exactly the card I wanted, easier to order and arrived in less time than anticipated.
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In the competitive world of business, skilled playing cards have an essential and crucial role to play. Bannersnack has the whole lot it's essential begin creating a cool enterprise card: skilled templates, beautiful fonts, and inventive inventory photos. Should you're simply fascinated by one-off purchases for making enterprise playing cards in Google Docs , then GraphicRiver may be a better option for you.
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Enticing design of the cardboard can encourage the shopper to start the business with the organization. Might it be for Enterprise, Work, Interest or for a Startup, Business Card Maker has designs to swimsuit any type. Seems that whenever you make it easy to create attention-grabbing issues, that's exactly what people do. All those great, random blogs your folks send you, those are Tumblr blogs.
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Design enterprise cards that are completely memorable. Though the opposite approach spherical is you could give you then thought of a design they usually can print it. The calendars serve the double function of giving out the days and the dates of the month as well as having your organization name on it.
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Unique or unusual cards are clever however not exactly suited to the enterprise surroundings. We provide you with high-quality enterprise playing cards at reasonably priced costs and free transport. Namecheap, one of the world's largest domain registrars and a number one international website hosting supplier , has announced 'Enterprise Card Maker,' its new international enterprise card printing service powered by Gelato.
With attractive enterprise cards accessible very inexpensively it is sensible for everyone to hold business cards with them. Interactive Q&A customized for logo & business card projects. Design and printing services could be very expensive, but Adobe Spark lets you make your individual business cards free of charge. Digital business card are very helpful to share contacts.
Business cards are stationery objects used to attach individuals with what you are promoting and reworking them in clients. An entrepreneur can create a printed or digital professional card. Make enterprise playing cards for anyplace on this planet. A designer can make in depth use of excellent high quality of paper for printing playing cards.
Pleasant Recycled Cards
The enterprise card is one of the most used and least understood tools in enterprise as we speak. Promotion can are available many types, however utilizing enterprise cards to symbolize a gift certificates will make it easier to your potential customer to not lose it. You can difficulty present certificates for a two-for-one dinner, a reduction when coming into your retailer, or for time on the driving vary.
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Software to help professionals create enterprise cards via templates or customized design and a database to keep track of all contacts. Tailor Manufacturers doesn't provide printing companies, so whenever you buy enterprise cards and letterhead, you're receiving design information which might be perfectly aligned with your business. A restaurant I visit each couple of months has a cork wall board bristling with enterprise playing cards.


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What is Triple-Negative Breast Cancer?
Learn more about triple-negative breast cancer, how common it is, survival rates, and treatment options on our cancer education blog.
Something you might not realize is that breast cancer is not a single disease, but rather a broad term that covers a number of different types of the disease. Because of this, your treatment plan may look completely different than another patient's treatment plan, all because of your specific breast cancer type.
At Rocky Mountain Breast Specialists (RMBS), we understand that learning about breast cancer can be overwhelming, especially if you were recently diagnosed. It's a challenge not only for you but also for your friends and relatives. One of the biggest questions you may be asked is, "What kind of breast cancer is it?" That's because the type affects the breast cancer treatments you're going to receive.
Determining the type of breast cancer is a process that involves an evaluation of the tissue sample collected from your breast biopsy.
We will then use that information to create a personalized treatment course that reflects your goals, personal desires, and unique nature of your particular type of breast cancer.
If you're just learning about breast cancer after a diagnosis and would like to schedule a consultation with one of our breast cancer specialists, request an appointment at one of the Rocky Mountain Breast Specialists locations throughout Colorado.
Want to learn more about breast cancer? Our breast cancer education center includes articles, videos, and patient stories.
On a broader scale, breast cancer can occur in two categories: invasive and noninvasive. Cancer categorized as invasive (infiltrating) means the cancer has spread to other parts of the body. Noninvasive (in situ) cancer, on the other hand, means that the cancerous cells are still confined to their point of origin.
Navigating the language of cancer can be confusing, especially when it comes to learning about the different types of breast cancer. Know that we will be with you every step of the way and are here to answer any questions you may have regarding your specific breast cancer type.
Some breast cancers are more common than others. These common types include:
Invasive ductal carcinoma (IDC) means that abnormal cells that originated in the lining of the breast milk duct have invaded surrounding tissue. Over time, IDC can spread to the lymph nodes and possibly to other areas of the body. This is the most common type of breast cancer, accounting for approximately 80% of all breast cancers.
Ductal carcinoma in situ (DCIS) is a non-invasive breast cancer where abnormal cells have been contained in the lining of the breast milk duct. Although it isn't considered life-threatening, DCIS can increase the risk of developing an invasive breast cancer later on. Most recurrences happen within 5-10 years after initial diagnosis.
Lobular carcinoma in situ (LCIS), also sometimes called lobular neoplasia, is actually not considered a cancer or a pre-cancer. This is because LCIS doesn't turn into invasive cancer if untreated. Rather, LCIS is an indication that a person is at a higher risk of getting breast cancer later on.
Invasive lobular carcinoma (ILC) starts in the milk-producing glands (lobules) and can spread to other parts of the body. It is the second most common form of invasive breast cancer, accounting for 10 to 15% of breast cancer cases.
Get helpful tips on what to expect and how to prepare your mind and body for breast cancer treatment.
Because breast cancer is not a one-size-fits-all disease, neither is treatment. Typically, your breast cancer treatment plan will be personalized and based on your specific stage and type of breast cancer. However, it is critical to determine which hormones, if any, are involved in the growth of your breast cancer.
Your RMBS oncologist will run some tests that indicate the hormone receptor status and HER2/neu (a protein found in some types of cancer cells) status of your breast cancer tumor. These results will play a large role in the type of breast cancer treatment that we recommend for you.
The hormone receptor status of your breast cancer refers to whether your breast cancer cells are fueled by estrogen and/or progesterone (the naturally occurring hormones in the female body) due to special proteins inside the tumor cells, called hormone receptors. When hormones attach to hormone receptors, the cancer cells grow.
A hormone receptor status is either hormone receptor (HR) positive or hormone receptor (HR) negative.
When these receptors attach to the hormones estrogen and progesterone and grow, it can leave you with one of four results:
If your cancer appears to be aggressive and fast-growing, you might have higher levels of a protein called human epidermal growth factor receptor 2, or HER2 for short. Some genes, like HER2 and the proteins they make, do more than play a role in the development of breast cancer. They can also influence how your breast cancer behaves as well as how it may respond to a specific cancer treatment.
Normally, HER2 receptors help control how a healthy breast cell grows, divides, and repairs itself. However, if the HER2 gene doesn't work correctly and produces too many copies of itself, it leads to uncontrolled growth of breast cancer cells.
If your breast cancer is HER2-negative, it means that you do not have an excess of the HER2 gene. Tumors such as these will not respond to therapies that specifically target HER2 receptors.
If your breast cancer is HER2-positive, then you have too much HER2 protein or extra copies of the HER2 gene. These breast cancers tend to be fast-growing. HER2-positive breast cancer treatment typically includes targeted therapy drugs that slow the growth and kill these cancer cells. HER2-positive breast cancers account for about 25% of all breast cancer cases.
Knowing your HER2 status will help your RMBS cancer care team create the best treatment plan for you.
Although the breast cancers listed above are the most common, there are some rarer breast cancers that are still worth knowing more about, which include:
A less common type of breast cancer, accounting for 1-3% of all breast cancers, is inflammatory breast cancer (IBC). IBC often appears to be an infection (breast is red, swollen, and inflamed) but it is actually cancer that is blocking lymphatic vessels in the skin and breast tissue, causing a buildup of fluid (lymph).
This type of breast cancer starts in the breast ducts and spreads to the skin of the nipple and then to the areola, the dark circle around the nipple. This type of breast cancer only accounts for about 1% of all cases of breast cancer.
Phyllodes tumors are rare breast tumors. These tumors develop in the connective tissue (stroma) of the breast and grow in a leaf-like pattern. Although phyllodes tumors tend to grow quickly, they rarely spread outside the breast.
Angiosarcoma is a cancer in the inner lining of blood vessels that can occur in any part of the body. This form of cancer rarely occurs in the breast.

subset: commoncrawl


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JK Rowling was the mind behind the Harry Potter book series, but Warner Bros. is making it clear it will not be her mind making its latest Harry Potter video game.
Hogwarts Legacy is an action RPG Warner Bros. shared a new trailer and more details about on Wednesday at a Sony games event where we got a release date and, finally, a price for the PlayStation 5. But one thing that wasn't made clear enough for some fans was whether J.K. Rowling, the creator and writer of all Harry Potter books the game is based on, will be involved in the making of the game itself.
The concern comes after a long series of anti-transgender comments and writings from Rowling, both online and most recently revealed in the contents of a new book written under a male pseudonym. That drew fresh outrage in a summer where Rowling has returned a humanitarian award and seen her comments rebuked by Harry Potter fan sites, actors from the Harry Potter movies and fellow authors. Which may be why on Thursday, Warner Bros. posted a FAQ about Hogwarts Legacy which directly answered whether Rowling is involved in the game.
Q: What is J.K. Rowling's involvement with the game? Is this a new story from J.K. Rowling?
A: J.K. Rowling is not directly involved in the creation of the game, however, her extraordinary body of writing is the foundation of all projects in the Wizarding World.
This is not a new story from J.K. Rowling.
Since it's a licensed Harry Potter work it seems likely that Rowling would profit from the game, but much like the company did earlier in the summer it's making it clear that Rowling is not involved in the work made with her IP. Having the author of the original work involved in a property based off of it is, usually, a fact that can be advertised as a good thing. That doesn't seem to be the case with Rowling these days.


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Jordan recently signed $10B deal with Russia to build first plants, desperate to extract itself from volatility of oil
Plan grants increased water access to all three parties, but environmentalists warn of unpredictable consequences


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Though no legislation has been passed yet, California officials have made it clear they want to outlaw automobiles powered by internal-combustion engines. But it's a near certainty they won't be able to secure an all-electric fleet within their timetable no matter how much they want it to happen.
Democratic state Assemblyman Phil Ting of San Francisco, state Air Resources Board Chairman Mary Nichols, and former Gov. Jerry Brown have all publicly entertained the idea of requiring Californians to switch. Ting has gone so far as to introduce legislation that would ban fossil-fuel powered vehicles by 2040.
Not even former Gov. Arnold Schwarzenegger's silly effort to boost EVs by posing as a car salesman for hidden video cameras can change the harshness of cold facts.View Article


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Popularity Contest is a WordPress plug-in written by Alex King. It gives your posts a popularity rating base on these values: Permalink Views, Home Views, Archive Views, Category Views, Feed Views, Comments, Pingbacks, Trackbacks. You also have the ability to change the weight of all of these values. For example, if you value Feed view more than comments, you can adjust the value of Feed Views to be greater than comments. The total of all values added together is the posts popularity. The popularity of the post is then displayed on your page as a percentage.
The main reason I decided to try this plug-in was that we have had a Popular Posts page on teamtutorials.com for a while now, but I never really update it. It was entirely up to me to decide what was popular. I would consider a post with a high number of comments or page view to be a popular post then I would add it to our popular posts page. I have finally found a plug-in that will do it for me (it is actually not a new plug-in).
My intention was to use the plug-in to generate a list of the 20 most popular posts on our popular posts page. I came to realize that WordPress didn't support PHP in posts by default (which is a good thing from a security standpoint). So I had to find a way around that issue by including the plug-in in the WordPress Loop. I will show you how to do this later on in the loop. If you just want to add the sidebar of your site, you will still find this tutorial very helpful.
First off, you will need to download the latest version of the Popularity Contest plug-in from Alex King's blog. As o the time I am writing this post the current version is 1.2.1 which was last changed on 006-11-05. He also is working on a beta 1.3 version which is supposed to work with WordPress 2.3. I am using the 1.2.1 and it seems to work ok with WordPress version 2.3 so far. Download version 1.2.1 now.
Save the file to disk and extract the folder from the zip file.
Once the files are extracted, upload the popularity-contest.php file to your WordPress plug-in directory (usually located at /wp-content/plugins/ ).
Now sign into your Admin account and active the plug-in.
Now we can adjust the values by clicking on the Popularity Values link.
On the Property Values page you can change the weight for each value below.
I left the default values, but you can change them as you want. The plug-in give you an example of how these values work. So if you have 10 permalink views and permalink views are valued at 10 than that would be 100 points. The plug-in does this for each value and adds them all together to determine the popularity.
If you scroll down you will see some examples of how to use the script in your theme. If you wanted to add just the top 10 post to the side bar you would copy the code below (stating at the arrow).
Then you would paste the code in your sidebar.php file where you wanted it to appear. You can edit the side bar via FTP or the WordPress admin panel if you have access to modify the files. I prefer FTP so I will edit the file /wp-content/themes/test/sidebar.php (note: test is the name of my theme, replace it with the name of your current theme).
Paste the code where you want it to appear in your sidebar.php file. Save the changes and upload the file to your server.
Now you can launch your site to see if the plug-in is working. You should see something like below.
Now if you want to add a static page that contains your most popular posts (like we did on teamtutorials.com) it is a little more difficult, but not too bad. The first step is creating a static WordPress page in your dashboard. It is only necessary to give your post a title, since the content will not be displayed for this page. Make sure you are creating a Page not a Post. So give your page a title and publish it.
Now you should have a blank paged that is titled "Popular Posts". It would be nice if you could just post the PHP in the box for the page, but WordPress will not allow this for security reasons. We need to make a change the WordPress Loop. Edit your index.php file for your theme.
Notice the code above may be different from your current theme. I am displaying only post excerpts on the min page of the blog. What is this code doing? First it checks if you are viewing a page (an actual WordPress page and not a post page). If I is a post or a single page it will display the content. If it does not meet these conditions (like the main page for example) it will display post excerpts.
Now to change the loop we will need to add some PHP to the content part of the loop. If you are using post excerpts your code will need to look like this.
Basically what I did above is I added another if statement and change the original one to an elseif So it is saying if page is 14 (which is the ID of my popular posts page. This is found at the end of the URL in the browser) then display the most popular posts. Now on my test site I am using the default URL's. On teamtutorials.com we use clean URL's so the code would be. if (is_page('greates-hits')) which is the URL to our popular posts page.
Make the changes and upload the index.php file to your server. You should see a list of popular posts on the popular pots page and not on any other page.
That is it. Now if you are now showing experts on the main page you will need to adjust the code accordingly. Feel free to leave comments or questions.


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Knee Deep Act 1: Wonderland is part one of a trio of narrative-driven adventure titles from indie developer Prologue Games. While Telltale has long had a stranglehold on the adventure genre, Knee Deep is entirely unique in its style, harking back to the glory days of classic adventure games like Grim Fandango and the Monkey Island series. While the variation in its text-heavy, pulpy world isn't always successful, it's different enough that you should stand up and take note.
Knee Deep takes place in the murky depths of the Florida bayou, in a sleepy little backwater town called Cypress Knee. The town is as much a character as the central trio you play as, who are markedly different but all there for just one reason – to find the truth. The story opens with the death of Tag Kern, a Hollywood celebrity and eccentric who had converted to the cult-like Church of Us. Kern decides to hang himself from a tourist attraction for reasons entirely unknown to his nearest and dearest. Naturally, all is not as it seems, and the whispers of suicide turn to twisted tales of a possible murder.
You take on the role of three different characters: Romana Teaque, Jack Bellet and K.C Gaddis. Teague is a cheeky blogger trying to find a story to stop her losing her job. Jack Bellet is a grizzled newspaper reporter, pestered on all sides by an overbearing boss and a dragon of an ex-wife, and K.C Gaddis is on the verge of eating a bullet before a call comes to investigate Kern's death. He also has a dog, because every video game needs a dog.
Knee Deep has an entirely novel approach to its storytelling, and doesn't bother with convention. The opening of the game pitches it as a stage play in three acts, and everything in the game takes place on the boards of this virtual theatre. In fact, the first branching options are to decide whether you want to read the playbill, or turn off your cellphone.
Characters move between locations instantly, crossing state lines and passing through walls as sets rise, fall and are wheeled away as if by magic. Knee Deep sticks to this stage conceit throughout the entire act, with everything being in service to the story. There are no fetch quests or pointless, time wasting puzzles that have always plagued contemporaries like Life is Strange or Telltale's The Walking Dead. Prologue's game is entirely about the story and the characters around you.
Strangely, it's also about journalistic integrity and honesty. Each character has the opportunity to gather the facts they've been told and collate them into a news story of sorts. These stories not only color how each character's employee feels about them, but it also affects the way other characters react to you in later interactions.
Early on, my Romana faced a cold shoulder or two for implying that Kern was washed up, and that Cypress Knee was the kind of place were dreams go to die. Maybe that's all true, but there's a fascinating amount of considerations in choosing the "stance" of your story. In Romana's gameplay, you essentially select a pre-written piece by choosing a theme that includes the likes of "Edgy" or "Cautious."
Edgy stories will please your editor, while cautious stories will please the locals. There's a fine line, and it's hard to tell how this will play out as Act 1 is simply setting up many of the story strands rather than following up on them. Future acts will tell us whether these choices truly matter at all.
Each character has a different role, personality, and way of reporting. Romana makes bite size, hipster headlines for the oh-so-trendy blog she works for. Bellet chooses how he wants to spin the story in his newspaper article for a local rag, and Gaddis essentially writes an expenses statement that comically changes on how you've framed the trip. As the game unfolds, you have multiple stories to cover, and there's a miniature battle between integrity, trying not to offend the victims or locals, and trying to please your boss. A battle not unlike the one most of us experience in our day-to-day lives.
The focus on story is the game's largest strength and occasionally one of its prime issues, too. Knee Deep is ostensibly all about story, and there is very little actual gameplay in the traditional sense. There are one or two mini-games that take away from the experience, feeling like something shoehorned in like any sort of puzzle in a Telltale game. The brisk pace of hopping between locations, characters, and conversations can often lead to slight confusion over who is who, and what role they play in the wider story. There are also a couple of story beats that are ruined by a brief struggle to recall who it is that is involved.
The game has an encyclopedia of sorts that allows you to view clues, facts, and character bios, and it alerts you when details are added to this, but the story is so gripping and propels you forward at such a pace that you rarely take the time to view it. Knee Deep flings you from location to location, and you never properly have control over a character to take a breather and stroll around. It gives it a wonderful, break-neck pace, making you truly feel like you're caught up in a stage play, but it can be overwhelming when you're trying to get your bearings and catch up on the facts you've found. It's a style that suits the pace of the game, but one that can occasionally leave you lost.
The voice acting in Act 1 is decent, and it's strange to note that the original release didn't include voice acting at all. It has been retroactively added into Act 1 for the release of the upcoming Act 2: Festival, coming November 3rd, 2015. Improved character animations and facial expression have also been added, adding a new level of depth to the experience.
It's refreshing to see a developer so ready to respond to negative and positive feedback alike and implement changes that improve subsequent episodes for the best. It's also telling that it's a better approach than developing an episodic series wholesale and then releasing them part by part. If all three acts were done and dusted and Prologue Games had no desire to return to them, the whole series would suffer as a result. Without voice acting, the maiden episode was still great, but the addition has added an extra level of polish and narrative style, even if it can feel somewhat wooden at times. The lines are always fantastic, however, which is better than can be said for other titles in the genre.
The location of Cypress Knee is so well realized that while you're aware of the stage trappings, you'd swear you can feel the oppressive heat, and smell the festering stench of the swamp as you engage with its motley crew of characters. Most of them are stereotypes at first glance that belie surprising depth.
Teague seems to start off as a typical, Generation Y'er, aloof and edgy, but as the episode progresses, it's revealed that there might be a very good reason for her closed off and disinterested facade, and for such a short title – just under two hours running time – we subtly cover a great deal of character history. Teague's "Give a strange response" dialogue option is also frequently hilarious and one of my favorite things about the game, allowing you to respond to other characters with quips and gibberish that often capture exactly how you feel, even though you didn't know it yet.
At its denouement, Knee Deep Act 1: Wonderland somewhat jumps the shark in a scene that is expertly crafted, jumping between interlinking characters to allow them to finish each other's sentences. The last five minutes or so feel like a series of twists, turns, and violence that are at odds with the sleepy pace at the start of the act. It's obviously a ploy to hook you in, to make you desperate to see what happens next – and heck, it works, even if it does feel cheap. As the curtain falls on the end of Act 1, I'm incredibly excited to see where Act 2 will take us.
This review is based on the PC version of the game, which was provided to us.
Knee Depp is a creative indie with stellar story, pulpy dialogue and serviceable voice acting.
Knee Deep Act 1: Wonderland Review


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In a remote estate in England, a governess, looking after two orphaned children, begins to believe that the house is haunted, though it may be only a figment of her imagination. When the boy, Miles, is expelled from his boarding school for a reason he won't divulge, the governess fears he is keeping a sinister secret. Then, one day, his sister Flora leaves the house without permission and refuses to ever see to governess again. This increases the suspicions of the latter that the children have been communicating with the ghost.
This novella is a foundational work of gothic horror fiction and is one of Henry James' most celebrated works. This beautiful old edition from Zephyr Books is in very good condition with the cover preserved in plastic, making it not only a beautiful edition to a bookshelf, but a book you won't worry about taking with you on a picnic for fear of destroying it.


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One of the most valuable life-saving skills a concealed carrier can learn is weak-handed shooting.
Weak-handed shooting simply refers to using your firearm with your non-dominant hand.
It's the hand you don't use for fine motor tasks. Basically, the one that gets neglected when you write, catch a ball, or grab an apple from the office snack bar.
But why is weak-hand shooting a skill you should learn and how do you even shoot with your non-dominant hand?
Today we are going to dive headfirst into weak-handed shooting! We'll explain the reasoning behind buffing up those skills and give you some drills to work on at home and at the range.
Table of Contents
Why Learn Weak-Handed Shooting?
The biggest reason to learn how to shoot weak-handed is in case you are ever forced into a situation where your strong hand is injured beyond the point of use.
Considering violent events, it's very much in the realm of possibility that your dominant hand could become compromised.
When thrown into a violent confrontation you may need to use your hands to defend yourself until it's safe to pull a gun. This may mean striking an opponent, which can also mean a broken hand.
Firing a weapon safely and accurately with a broken hand is challenging to say the least.
You could also be involved in a gunfight where your arm or hand becomes injured by gunfire.
If your dominant hand gets hurt, it's critical you stay in the fight. So, you need to be a skilled weak hand shooter to improve your chances of survival.
Of course, you want to stop the threat. But if you suck at weak hand shooting, you will likely miss, and if you miss that bullet still has to go somewhere.
Remember, you are held responsible for every round you fire.
Having the ability to use both hands is part of the responsibility of knowing how to use your weapon safely and responsibly.
Weak handed Shooting Techniques
There are two basic techniques to use when shooting with your weak hand — straight arm and cant.
Kind of like choosing between the Weaver and Isosceles stance this will largely be up to the individual shooter.
Try out both and see what feels more natural to you.
Straight Arm Technique
The straight arm technique is very simple.
Drive your weak hand forward until the elbow locks in place, resulting in the weapon being parallel up and down.
This technique replicates most standard shooting positions and gives shooter's a predictable upward recoil.
Many shooters prefer to keep things as close to standard two-handed shooting as possible.
If you run a miniature red dot on your carry gun, this technique may be more valuable due to familiarity with 'finding' the dot.
Canted Technique
The canted technique involves driving the firearm straight out in front of you, locking your elbow, and canting the weapon anywhere from 10- to 45-degrees.
A lot of people find this position to be more natural and comfortable. It can also make using your dominant eye more natural.
For example, if you're right hand and right eye dominant crossing your body with your left hand, allows you to use your dominant eye.
But you are right-hand dominant and left eye dominant this technique isn't as advantageous.
Not sure what your eye dominance is? We got you. Take a look at our Eye Dominance Guide here.
What to Do with The Other Hand
This really just depends on just how injured your hand is.
If the damage is in the arm it may be best to let it hang naturally until it is safe to apply first aid.
If the injury is to the hand, it's a good idea to bring the hand into your chest to give you a more balanced position and keep the damaged hand out of the way.
The last thing you want is for an injured hand to strike something while you run and gun to safety.
In an extremely close quarter fight, it will also protect the hand from someone attempting to grab it.
Your Stance
I won't go too deep into what to do with your stance.
Like any situation, you want your legs shoulder-width apart, and your weight forward.
Since you only have to use one hand, you can also blade your body a bit. This will make you a smaller target overall, and that is always a good thing.
Weak Handed Weapon's Manipulation
When we say shooting, it's easy to focus on just the act of pulling the trigger and hearing the bang.
Without a doubt, shooting is the most important part of weak-handed weapon manipulation. But that's not all there is to it.
You'll need to be able to effectively manipulate your weapon in a variety of situations to ensure you'll always come out on top.
Before you can shoot your gun you need to be able to get the gun into action.
Depending on how you carry this can be simple or quite challenging.
Appendix carry makes drawing with your off-hand quite easy, strong side carry is a slight challenge, and pocket carry is basically impossible.
To draw from the strong side you'll reach over with your non-dominant hand and grip the weapon in an inverted manner, so your thumb will be facing the magazine of an automatic.
Pull the weapon from the holster and bring it under your arm.
Pin the weapon between your body and arm, and use your weak hand to assume a proper grip. Engage the target.
From an appendix position, you can simply reach over and grip and rip the gun from its holster.
This is easily the fastest method to draw your firearm with a weak hand. There are numerous benefits to appendix carry, and this is certainly one of them.
Reloading a semi-auto with the weak hand is quite simple.
With the slide locked to the rear place the gun between your knees with the grip facing upwards. Insert the magazine, ensure it's locked into place, and remove the gun from between your knees. Use your hand to hit the slide release and get back into the fight.
A revolver is a little more challenging, especially a snub nose.
This assumes you'll be reloading with a speedloader or moon clip.
Open the cylinder by pressing, pushing, or pulling the release and flick the wrist to allow the cylinder to pop out. You can push the ejection rod against anything that can push it. If nothing is available, take a knee and use your shoe if you have to.
With the cylinder hanging out of the weapon, place it between your belt and your body. Again, challenging, but possible with a snub nose.
Drop the moon clip or speed loader in. Retrieve the weapon and push the cylinder in place.
Obviously, neither of these weapons are fast, and both assume your dominant hand is completely and totally out of the fight. If you can use your dominant hand to help you, I'd advise doing so.
Drawing and reloading are both skills that should be practiced extensively. These should be perfected through dry fire first.
Do not move to live fire training until you are absolutely positive you can draw and reload with live ammo safely.
Support Hand Drills
You now know the how of shooting with a single arm; so let's talk about what you can do to get better at shooting with one hand.
Above we make it sound and look easy, but it is one of the more challenging aspects of firearm handling.
As such, it's time to get some training.
Dry Fire
This should go without saying. Get out there and do some dry fire with one hand.
But swap hands and get equal practice with both hands.
This will get you used to the act and the effort required.
You can also experiment with some of the techniques above and find what works for you. This makes it easy to pick what works for you when you go to the range.
Hold Something
When dry firing at the range, I challenge you to hold something with some heft to it — I use a kettlebell.
You want a little weight, nothing crazy, but something like a gallon of water.
This truly takes your arm out of the fight and feels representative of holding a child back or having a massively wounded arm.
It makes one-handed shooting a little bit tougher and makes it a true one-handed affair.
Use the Dot Torture – One Hand Only
Dot Torture stretches a wide variety of skills throughout 50 rounds of ammunition.
Two of the 10 dots challenge you to shoot with a single hand.
Well, to that, I say, let's shoot all 10 dots with one hand! Shoot it twice, once with each hand.
This will challenge you to do more than shoot. You'll need to reload with one hand, draw with one hand, and sometimes draw with your off-hand.
Go slow with these skills and build them.
It's a frustrating thrill that will challenge the hell out of you.
Switch Hitting
Created by the late Todd Green, Switch Hitting focuses on single-hand shooting. Set up two small targets about a foot apart — 3×5 cards work.
Set a par time of 10 seconds. Start 3 feet from the targets with a gun in your strong hand only.
Engage the target on your strong side with one round and pass the gun to your non-dominant hand. Then fire one shot on the opposite target.
Repeat this until both targets have two holes in them. It should be doable in 10 seconds.
Obviously, be careful handling a hot gun. If it's too easy, crank up the distance and try again.
Draw And Engage
This is a very simple drill. Get two fairly large targets. I use man-sized printables from Sage Dynamics.
These targets only focus on the vitals of a bad guy and prove quite nice for training purposes.
Start at 10 yards with the targets at least a yard apart. Set a par time for 10 seconds. Draw with your dominant hand and engage each target with two rounds in 10 seconds.
Focus on your accuracy. Ten seconds is a long time! Make those shots count and apply speed when possible.
Switch to your non-dominant hand and practice drawing and engaging with the same amount of rounds.
Those 10 seconds will feel a lot shorter here. Still, be safe and go slow with it.
Learning to shoot with your weak hand is a skill that could save your life, and it's also a difficult and challenging new skill to learn.
If you live by the motto that you're a beginner only once, but a student forever, then weak hand shooting should be a skill on your gunfighting syllabus.
How do you train weak-handed shooting? Let us know in the comments below. Looking to strengthen your skills? Check out our recommendations for the Best Shooting Drills.


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Taj Burrow (AUS), 34, winner of last year's Reef Hawaiian Pro.
HALEIWA, Oahu/Hawaii – (Friday, November 9, 2012) - The $1million Vans Triple Crown of Surfing hydrated by vitaminwater is making final preparations for the official start next Monday, November 12. The first jewel of the Vans Triple Crown is the Reef Hawaiian Pro, to be held at Haleiwa Ali'i Beach Park on the four best days of surf during the period of November 12-24.
"There's a good chance that we will take advantage of a small swell on offer right off the bat on Monday so that we can get the first round under our belt," said Vans Triple Crown Executive Director Randy Rarick, "as better conditions are expected later next week and towards the end of the Reef Hawaiian Pro period."
Daily swell forecast updates will be provided to event organizers starting tomorrow by Surfline.com, official forecaster for the Vans Triple Crown of Surfing.
"Haleiwa is a high performance wave regardless of its size and it's the perfect stage for launching our 2012 Hawaiian Air Show that will showcase all of the technical and progressive aerial maneuvers of leading athletes like John Florence (Hawaii), Dane Reynolds (California), Gabriel Medina (Brazil), Josh Kerr (Australia), and last year's Air Show winner Nat Young (California)," said Rarick.
The Hawaiian Air Show offers 250,000 Hawaiian Airlines Miles to the surfer who executes the most progressive aerial maneuver during the 6 weeks of the Vans Triple Crown of Surfing.
This winter we celebrate the 30th anniversary of the Vans Triple Crown with a record prize purse and a $100,000 bonus to the series champion. In addition to individual event and overall series champions, the final event of the Series – the Pipe Masters, will determine the 2012 ASP World Champion.
As part of the Reef Hawaiian Pro, Reef will partner up with "Waste to Waves" for a Foam Drive during the event. They will also present the Reef "Clash of the Legends" featuring Tom Curren, Mark Occhilupo, Sunny Garcia, and Kaipo Jaquias.
Each of the three events of the Vans Triple Crown of Surfing has a two-week holding period within which to run, requiring just 3-4 days of excellent surf to be completed. To find out when the event is running, log on to:
Twitter @vanssurf using #VTCS
Instagram @vanstriplecrownsurf


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Thomas Arendt graduated with a medical diploma and a medical thesis from the Medical Faculty of Leipzig University in 1982 and subsequently received a postdoctoral training in neurochemistry, neuroanatomy and neuropathology (Leipzig University). In 1984, he worked as a visiting scientist in the Academy of Medical Sciences in Moskow and in 1986/1987 he received a Wellcome Fellowship and joined the group of Prof Gray and Prof.Marchbanks at the Institute of Psychiatry, University of London to work on experimental behavioural sciences and stem cell transplantation as an experimental approach to counteract neurodegenerative processes. From 1987 to 1996, he was research group leader at the Paul Flechsig Institute. In 1990 he was promoted to a Doctor of Science for Neuroscience (Habilitation and venia legendi). He became full Professor for Neuroanatomy and Head of the Department for Neuroanatomy at the Paul Flechsig Institute in 1996. Since 2005, he is Managing Director of the Paul Flechsig Institute of Brain Research. Over the last 40 years he has been working on therapeutic and diagnostic strategies of neurodegenerative disorders. In the early eighties of the 20th century, he was involved in identifying the degeneration of the cholinergic system in Alzheimer´s disease laying the basis for todays´ only available treatment. He is one of the pioneers of the "cell-cycle theory" of Alzheimer´s disease which he developed further towards a diagnostic and therapeutic concept.
Anne-Laurence Boutillier performed her PhD in Neurosciences in Strasbourg (France). She studied the transcriptional regulation of a pituitary gene (the pro-opiomelacortin gene), studies she continued during her post-doctoral training at Mount Sinaï in New York. Hired in 1996 at the CNRS, she started investigating the mechanisms of neuronal survival and death in simplified models and later in animal models of neurodegenerative diseases, with a strong interest in the CREB Binding Protein (CBP), a transcriptional co-activator with acetyltransferase functions. Since 2013, she co-directs a team at LNCA that studies the implication of epigenetic regulations in neuro-plasticity and neuronal activity during learning and memory. Epigenetic regulations are essential for the spatio-temporal regulation of gene expression. By integrating environmental factors in transcriptional responses, they allow the adaptation of the genome to the environment. The team's projects aim to characterise epigenetic and transcriptomic signatures altered in neurodegenerative diseases such as Alzheimer disease and Huntington disease and decipher the underlying mechanisms in order to identify new targets for therapeutic interventions. Further studies are focussed at restoring proper epigenetic regulations in animal models by pharmacological (HAT activator molecule) or non-pharmacological (enriched environment, exercise, nutrition...) approaches.
Luc Buée is a French scientist (Directeur de Recherches au CNRS), Director of the new "Lille Neuroscience & Cognition" Institute and Head of the Inserm laboratory « Alzheimer & Tauopathies » at the University of Lille, France. His group is also part of the laboratory of Excellence (LabEx) DISTALZ and the Centre of Excellence in Neurodegenerative disorders (LiCEND). He has worked on Alzheimer disease and related disorders for about thirty years. He started his work on Alzheimer's disease with a PhD training at Mount Sinai Medical Center, NYC. He was then involved in the initial characterization of tau aggregates among neurodegenerative disorders. He has then developed experimental models to better understand the role of post-translational modifications in tau aggregation and tau secretion. His group is currently working on the pathophysiological consequences of neurofibrillary degeneration and their links to the amyloid pathology and neuroinflammation in Alzheimer disease. His group was/is also involved in different international consortia.
Luc Buée is also involved in different scientific advisory boards and operating committees (Inserm, Janssen Horizon, PSP France, Rainwater Charitable Foundation...). He is also the representative researcher elected by academics at the French Foundation Plan Alzheimer. He is the main organizer of the Eurotau meetings. Since November 2019, he is the President of the French Society for Neuroscience.
Dr. Julien Chapuis has been an Assistant Professor at the University of Lille, France since 2014. In 2015, he received research support from the French Alzheimer's Association to study the genetic factors of AD involved in APP metabolism. He has been developing his own project based on new cellular High Content Screening models to characterize the functionality of the genetic risk factors identified by GWAS approach and in particular their impacts on the APP metabolism.
Associated publication:
Dourlen P, Kilinc D, Malmanche N, Chapuis J, Lambert JC. The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis? Acta Neuropathol. 2019
Dourlen P, Chapuis J, Lambert JC. Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS Signals. Curr Genet Med Rep. 2018;6(3):107-115.
Chapuis J et al. Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism. Acta Neuropathol. 2017.
Dr. Marie-Christine Chartier-Harlin (Inserm Research director) is a specialist of Alzheimer's and Parkinson's disease. She defended in 1999 her PhD in Biochemistry and Molecular Biology at the University of Lille, France. She pursued a post-doctoral research as a research fellow on the Genetics of Alzheimer's disease (AD) in London (UK), where she discovered the first APP mutation in J Hardy's laboratory. After being recruited as an Inserm research scientist (1993), she came back to France and worked on the implication of the APOE gene in AD and AD process using molecular and biological methodologies. In 2001, she became Inserm research director, pursuing work on AD as well as Parkinson's disease (PD), and since 2005, she has devoted more attention on PD after she found that the sole overexpression of the alpha-synuclein is sufficient to develop Parkinsonism in a dose dependent manner. She took the direction of the PD lab with Pr Destée 2010 and since 2015 her research combines clinical, genetic epidemiology and molecular approaches including gene expression and translation investigation since her recent work put forward the role of translation in PD. They also study pre-clinical models including murine and cellular models, biological samples of PD patients and controls from Lille' patient cohorts (>1000 AD and PD). This lab is part of Center of excellence labelled by the "Plan national sur les maladies neurodégénératives (2015)". Her Hirsch factor is 39 and her work was cited more than 10 470 times. Dr. Chartier-Harlin was member and then President of the scientific committee of the European League against Alzheimer's disease (LECMA (now Fondation Vaincre Alzheimer), 2005-2017) and is now member of its board of directors. She and her team received several prizes among which the Aimée et Raymond MANDE prize from the French National Academy of Medicine.
Frédéric Checler is a INSERM research Director (Exceptional class, DRCE INSERM) and head of the laboratory of Molecular and Cellular Biology Normal and Pathological Cerebral Aging at IPMC, Sophia Antipolis.
F. Checler received his PhD in Cellular and Molecular Pharmacology from University of Nice-Sophia-Antipolis (1983). He worked first on the field of proteases and neuropeptides metabolism, then moved to the fields of neurodegenerative diseases where he was mainly interested in proteolytic dysfunction and cell death mechanisms involved in Alzheimer's disease then on dysfunctions taking place in Parkinson's and prion diseases. More recently, his group has undertaken studies on cerebral cancers with the aim to delineate common denominators between neurodegenerative diseases and tumorigenesis.
F. Checler was ranked Top 1% researcher in the world "Biology and Biochemistry" (ISI WOK field of ranking at the end of 2011); He published over 250 articles in international journals, books, monographs, editorials, and reviews. He also attended 225 Invitations in International meetings and more than 100 invited seminars. Dr. Checler was the first President of the scientific committee of the European League against Alzheimer's disease (LECMA (now Fondation Vaincre Alzheimer), 2005-2010) and is now member its the board of directors. He has been a Member of the steering committee of the French Alzheimer plan launched by President N. Sarkozy. He belongs to the laboratory of Excellence DistALZ (Development of Innovative STrategies for translational Approach in ALZheimer Disease) that gathers nine first-class teams.
His honors include: the BioMerieux award (1997); 1999 MHRI Kearney Fellow Award, Mental Health Research Institute; the Charles-Louis de Saulces de Freycinet Award, French National Academy of Science (2002); the "Grand Prix" Jaffé of the French Academy of Sciences (2013); "Grand prix" of Pompidou foundation 2014; Medal of the Departmental council; Medal of the University of Nice-Sophia Antipolis (2013, 2014). He has been recently elected «foreign corresponding member of the Brazilian Academy of Sciences».
Dr. Holger Cynis is biologist by education. He received his PhD in biochemistry from university of Halle (Saale), Germany. Currently he is heading the group for Molecular Biotechnology at the Fraunhofer Institute for Cell Therapy and Immunology. Before joining Fraunhofer, he was a research fellow at the Center for Neurologic Disease, Brigham and Women's Hospital, Harvard Medical School, Boston, USA. Before switching to the academic world, he was project leader and senior scientist at Probiodrug AG, having 10 years of biotech experience. The major aim of Dr. Cynis' work is in vitro and in vivo pharmacology in the context of drug development programs for neurodegenerative and inflammatory disorders. Current interest is in the field of generating translational models for AD research and the role of endogenous retroviruses for the development of demyelinating disorders.
He successfully investigated human glutaminyl cyclases as novel drug targets in Alzheimer's disease and systemic inflammatory disorders. One particular interest was translational studies in cellular and animal models. Dr. Cynis has co-authored 10 patents and >30 publications. He is co-founder of PerioTrap Pharmaceuticals GmbH (2018).
Elly Hol is professor of "Glia biology of brain diseases" at the Utrecht University, professor of "Biology of glia and neural stem cells" at the University of Amsterdam, and a member of the Academia Europaea. She leads a research group at the University Medical Center Utrecht Brain Center. Her research is focused on the role of glial cells in brain diseases. The overall aim is to elucidate the molecular and functional changes in glia that contribute to the pathogenesis of neurological and psychiatric diseases. Her work is translational and includes studies on glial cells in human post-mortem brain tissue, in human cell models, and in mouse models for brain diseases. Elly was trained as a medical biologist with a specialization in molecular neurobiology. After her PhD in Utrecht, she obtained a Max-Planck Fellowship to work at the Max-Planck-Institute for Psychiatry in Martinsried. In 1997, she started as a post-doc at the Netherlands Institute for Neuroscience in Amsterdam, and between 2003 and 2013 she headed the group "Astrocyte Biology & Neurodegeneration". As of 2013 she works as a principal investigator at the department of translational neuroscience, UMC Utrecht Brain Center. She is in the editorial board of Glia, chair of the scientific advisory board of Alzheimer Nederland, chair of GliaNed, director of the Neuroscience Master and PhD program of the Utrecht University Graduate School of Life Sciences, and director of education Division Neuroscience at the UMCU.
Paul Lucassen is full professor at the Brain Plasticity goup at the Swammerdam Institute for Life Sciences, Center for Neurosciences (SILS-CNS) of the University of Amsterdam. Their research focusses on the molecular, nutritional, pharmacological and environmental regulation of Brain Plasticity. The main topics of their research revolve around adult neurogenesis & stem cells in relation to (early life) stress, nutrition, exercise, cognition, depression, epilepsy and Alzheimer's disease.
After obtaining his PhD cum laude at the Neth. Brain Institute, Amsterdam with Prof.Dr. Dick F. Swaab in 1995, Paul did a Postdoc on stress, apoptosis, APOE/dementia and depression at the LACDR in Leiden under the supervision of Prof. D.r E.R. De Kloet. From 1998 to 2011 he has been working as assistant Professor with Prof.Dr. M Joels, and later became associate Professor and group leader at the SILS-CNS of the University of Amsterdam. As of 2011 he was appointed as full professor of Brain plasticity and works as a principal investigator at this same institute. He is the author of more than 180 peer-reviewed scientific publications and 25 book chapters. He gave over 220 invited lectures. His Hirsch factor is 54 and his work was cited more than 9200 times. He received the Organon Price for Endocrinology in 1995 and the SILS Award in 2014. He is a visiting professor at the Wuhan University in China.
Manuela Neumann, M.D. is Professor of Neuropathology at the University of Tübingen, Germany, Medical Director of the Department of Neuropathology of the University Hospital, and Senior Group Leader at the German Center for Neurodegenerative Diseases.
Her main research focus is to unravel the molecular pathology and underlying pathomechanisms of neurodegenerative diseases by studying human tissues and animal models. She is internationally recognized for her pioneering work on the identification and characterization of TDP-43 and FET proteins in frontotemporal dementia and amyotrophic lateral sclerosis. She has published over 160 peer-reviewed articles and has received several prestigious research awards, including the European Grand Prix from the French Foundation for Research into Alzheimer's and the Alzheimer Research Award from the Hans&Ilse Breuer Foundation in 2012.
Manuela Neumann serves as a member of the editorial board of Acta Neuropathology and as member of the scientific advisory board of Alzforum and the Alzheimer-Forschungs Initiative e.V.
Dr. Henrietta Nielsen earned her PhD from Lund University researching serine protease inhibitors in relation to Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). She trained as a postdoctoral fellow at the VU Medical Center Amsterdam focusing on amyloid-beta clearance and the influence of amyloid-associated-proteins like apolipoproteins E and J in primary cultures of human astrocytes and microglia. Further work of hers at Lund University entailed biomarker discovery efforts focusing on CSF alpha-synuclein levels and various inflammatory markers in patients with AD and synucleinopathies like Parkinson's disease and DLB. Dr Nielsen also spent several years as a research associate at the Mayo Clinic in Jacksonville FL where she studied the individual apolipoprotein E isoform levels in plasma and CSF from AD and controls. Dr. Nielsen now heads the Translational Neurodegeneration Research Team at Stockholm University with major efforts invested in assessing the role of alpha-synuclein in AD pathophysiology, and potential links between liver-derived apolipoprotein E and neurodegeneration of the brain. She serves as a senior editor of Molecular Neurodegeneration and an associate editor of the Journal for Alzheimer's Disease while splitting her time between positions as an associate professor of neurochemistry at Stockholm University and an associate professor of molecular biology at Roskilde University.
Florence Pasquier, MD, PhD in Cognitive Psychology, is professor of Neurology, head of the Memory Clinic at the University Hospital of Lille, France, also the French Reference Centre for Young Onset Dementia.
She leads a network of memory clinics in the North of France (4 million inhabitants), and the Regional Network for Care of Demented Patients Méotis, which aims to coordinate public and private medical, social, and psychological resources for patients with dementia. She is involved in clinical research on cognitive and behavioural disorders in Alzheimer's disease and related disorders. She uses a multidisciplinary approach thanks to clinical and basic research collaborations in neurology, neuropsychology, behaviour, biology, and brain imaging.
Her main domains of interest are 1) early and differential diagnosis of dementia with a special concern about non-Alzheimer diseases (frontotemporal dementia, vascular dementia, dementia with Lewy bodies,…) especially frequent in young patients 2) the links between vascular and degenerative diseases, and 3) the natural history of dementia, with the aim of improving the clinical management of these diseases. ORCID https://orcid.org/0000-0001-9880-9788. She is PI of the Lille Centre of Excellence for Neurodegenerative Diseases LICEND, member of the Labex DISTALZ, of Inserm1171 "Cognitive impairment in neurodegenerative and vascular disorders", and current VP of the Inserm Neurosciences committee. Her group belongs to DIAN-TU, and GENFI-2.
MD & Medical license, 1994, Charles Univ., Prague, Czech Republic
DrMedSc (PhD) 1994, Uppsala Univ., Sweden
Docent (Assoc. Professor) 1999, Medical Biochemistry, GU, Sweden
Professor 2015- , Clinical Neuroscience, GU, Sweden
Member of Academia Europaea (Medicine and Physiology)
Prof. Pekny's laboratory focuses on the development of novel strategies for brain repair and regeneration. With their collaborators, they redefined the concept of reactive gliosis in injured brain (PNAS, 2006), and showed that reactive astrocytes play key roles after CNS trauma, in post-traumatic neuroprotection (J Cell Biol., 1999; J. Neurosci., 2004) and in the progression of neurodegenerative diseases (J. Neurosci., 2011; FASEB J., 2013). They demonstrated that the integration of neural transplants and neural stem cells can be improved by modulation of reactive gliosis (Nature Neurosci., 2003; Stem Cells, 2007), and showed that astrocytes control the neurogenic niche via Notch signaling which depends on the intermediate filament (nanofilament) system of astrocytes (Stem Cells, 2012; J. Neurochem., 2015; Cereb. Cortex, 2019). Pekny's laboratory demonstrated that reactive astrocytes play a major role in ischemic stroke, and identified astrocyte intermediate filaments as a potential target for pharmacological intervention in CNS diseases (JCBFM, 2008; Stroke, 2012; Physiol. Rev., 2014; Acta Neuropatol., 2016; Cerebral Cortex, 2017).
Dr. Stephan Schilling is biochemist by education. He received his PhD in biochemistry and habilitation (Dr. Sci.) in pharmacy from the university of Halle(Saale), Germany. Currently, he is heading the group for Protein and Drug Biochemistry at the Fraunhofer Institute for Cell Therapy and Immunology. Before joining Fraunhofer, he was project head and director of Enzymology at Probiodrug AG, having >10 years of biotech experience. The major aim of Dr. Schilling's work is drug target validation and discovery of lead molecule for treatment of neurodegenerative disorders, inflammation and fibrosis. One special research interest is the role of posttranslational modifications of proteins in pathophysiological conditions. He successfully investigated human glutaminyl cyclases as novel drug targets in Alzheimer's disease and systemic inflammatory disorders. One particular interest was translational studies in animal models for defining required target occupancy in clinics. Dr. Schilling has co-authored more than 25 patents and >60 publications. He is co-founder of Periotrap pharmaceuticals GmbH (2018).
Annerieke has always been fascinated by the complexity of the brain, i.e. how changes in its molecular and cellular components and its circuitry can affect how we think, feel and behave. During her studies in Biological and Neuropsychology, Annerieke became intrigued with memory formation and the loss of it in Alzheimer's disease. From 2007 to 2012 she conducted her PhD at the School of Mental Health and Neuroscience at Maastricht University (the Netherlands) in 2012, where she investigated the effects of prenatal stress and phosphodiesterase inhibition on the progression of Alzheimer's disease, gaining expertise in Alzheimer mouse models, mouse behavior, immunohistochemistry and microscopy. Wanting to enhance her molecular biology skills, she started her postdoc within the laboratory of Prof. Bart De Strooper. By using combining miRNA deep sequencing, qPCR, in situ hybridization, local miRNA overexpression and mouse behavior, she found 6 neuronally expressed miRNAs that could contribute to Alzheimer-related memory deficits. Moreover, by combining human GWAS data and mouse transcriptomics Annerieke unraveled that genetic risk for Alzheimer's disease determines how microglia react to amyloid-β pathology, but not to TAU pathology. Annerieke is currently continuing this line of research by investigating how microglia from people with high polygenic risk differ from those with a low polygenic risk.
Professor St George-Hyslop has made major contributions to the understanding of the functional genomics of multiple human neurodegenerative diseases including Alzheimer disease, frontotemporal dementia and ALS. He has played a major role in cloning of genes associated with susceptibility to these disorders including APP, APOE, PS1, PS2, SORL1, TREM2 and several others. He has built protein structural, molecular, cellular and animal models of these disorders, and used them to explore candidate therapeutics including early work on anti-Abeta vaccines, inhibitors of Abeta aggregation, and inhibitors of gamma-secretase, and microglial modulators such as CSF1R inhibitors. He is currently University Professor in the Division of Neurology, Department of Medicine at The University of Toronto, and Professor of Experimental Neuroscience at the University of Cambridge. He has received numerous academic honours including election to the Royal Society of London, Royal Society of Canada, US National Academy of Medicine, the Order of Canada and the UK Academy of Medical Sciences, as well as the Howard Hughes International Scholar Award, Potamkin prize, Metropolitan Life Award, Dan David Prize, Ryman Prize, Zenith Award and Royal College of Physicians of Canada Gold Medal in Medicine.
Prof. Harry Steinbusch is appointed as Professor in Cellular and Translational Neuroscience at University of Maastricht in the Netherlands. He is involved as Strategy Advisor Academic Relations in particular in relation to China, Japan and Korea. He is the Director of the Dutch - China Universities Network, including 12 Universities in both countries. He is Past-President of the International Neurotoxicity Society. He is Founding-Director of the European Graduate School of Neuroscience, a gathering of 8 universities in the EUregio, between the Netherlands, Germany, Belgium, France and Luxembourg. He has been involved for 13 years as Director of the School for Mental Health and Neuroscience at UM. He is Founding-Director of NENS - Network of European Neuroscience Schools. He is Founding and current Editor-in-Chief of the Journal of Chemical Neuroanatomy, current i.f. 2.4. He is affiliated with the KPMU in Kyoto, Japan; University Of Colombo, Sri Lanka; University of Sao Paulo, Brazil and Capital National University, Beijing, China.
His research interest is focused on the neurodevelopmental influences between depression and neurodegenerative diseases, i.e. Alzheimer's Disease as studied in animal models and human material. This approach will be implemented to start and prevent neurodegenerative processes. These studies uses a broad range of techniques, i.e. molecular neurobiology, quantitative neuromorphology, animal behavior and epigenetics. He has thus far guided 99 Ph.D. students. He has gathered a total of 495 papers. He has been twice coordinating a Marie Curie Early Stage Training site. He was coordinator of an Erasmus Mundus + program between 4 Euron universities and 3 universities in Japan. He is affiliated on 27 editorial board and member of 20 International review committees. His current Hirsch factor is 93, citations without self-citations: 34,538 and his M-factor is 2.3.
Wiesje van der Flier (1975) is full professor and head of clinical research at the Alzheimer center Amsterdam at Amsterdam UMC, the Netherlands, where she works since 2004. She studied neuropsychology at the University of Utrecht. In addition, she is clinical epidemiologist. She is leads the Amsterdam Dementia Cohort, an ongoing memory-clinic based cohort including over 6000 patients with deep phenotyping (MRI, EEG, CSF biomarkers, and PET) and linked biobank (blood, DNA, CSF). The Amsterdam Dementia Cohort is at the basis of many of the studies performed at the VUmc Alzheimer center. Van der Flier has been (co)promotor of >20 theses and is currently supervising ~10 PhD projects. Van der Fliers main research areas are (i) finding the origin of disease, (ii) diagnosis&prognosis, (iii) intervention and prevention. Together with colleague Philip Scheltens, she has written a book, het Alzheimermysterie, which was published by the Arbeiderspers.
Sheela Vyas is INSERM researcher in the Department of Neurosciences Paris-Seine at University of Sorbonne. She leads research team working on environmental stress and chronic inflammation in neurodegenerative diseases in the laboratory "Gene regulation and Adaptive behaviors". Her research focus is molecular dissection of actions of glucocorticoid, stress hormone which exert wide ranging regulatory actions impacting neuronal, immune and endocrine systems. The research is preclinical using refined mouse models, in vitro cell cultures and organotypic slices as well as translational involving patient samples.


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Staying on top of social media is one of the hardest parts of growing your blog (or business!). Which is why I made myself a social media schedule. To make sure I was staying on top of social media posts and staying consistent. So I wanted to share it with all of my blogging friends as well! So keep reading for my free social media printable calendar for bloggers.
I know that staying on top of all the different social media accounts and feed/ algorithm changes can be absolutely exhausting. And super overwhelming. But by using a calendar to track when you post and stay organized with content ideas and progress you can use social media to your advantage. Remember, social media can be an amazing way to not only drive traffic to your blog but also keep you connected with your audience.
Which means you can get better ideas of what your audience wants to see from your content and gives you a chance to build actual relationships with your most loyal audience. Both of those aspects are super essential for growing your blog platform.
This free social media schedule will help you stay on track to make sure you are posting enough and keep track of your engagement progress and all your awesome content ideas.
Below you will see the PNG as well as a link to actually download the image- and some more detailed instructions. Then below that I wanted to share some additional tips for using social media as a blogger and how to stay organized as a blogger.
Social Media Printable Calendar For Bloggers
*** This article may contain affiliate links that I receive a small commission off of. As an Amazon Associate I earn from qualifying purchases. I always appreciate any support to keep this site running! Thank you!***
How to use this social media printable calendar:
Click the image to open up the printable as a PNG and print it off (already letter size) or I recommend saving the image and uploading it to your free Canva account to add the text you want!
Below the image is also the PDF link as well if you prefer the PDF.
Check off as you post to keep track and hold yourself accountable. I use the note section to list out caption ideas but you can use it for whatever you want! And for progress I really like to keep track of engagement from followers!
Tips for using a social media calendars:
- Remember what the vision is for your brand and make sure that when your planning content that you focus on that vision.
- When you think of captions jot them down so you don't forget them.
- Track your progress and engagement. You can then look back at past weeks and see what you did to increase engagement across your social platforms.
- If you're feeling creative make sure to brainstorm ideas when you can.
- Remember to post during peak times (like 2pm-6pm on instagram and 7pm-10pm on Pinterest).
- Keep any hashtags authentic- putting a bunch of irrelevant hashtags won't have anyone engaging with your content and won't grow your engaged followers at all.
And really quickly I want to share some general organization tips and tricks as well. Because staying organized and consistent on your social media will be 100x easier if you are feeling organized overall!
Organization Tips and Tricks:
Getting organized is so important for staying on top of your social accounts and marketing for your brand. I also have a free printable and free downloadable weekly to do list (How To Write Weekly To-Do Lists + Free Template) that will help you as well.
I have also found that making sure I have a fully stocked camera bag (this is the one I am using now!) is so helpful for keeping you organized when you are getting social media content.
If you are on an organizational kick then make sure you are taking advantage of a full weekly planner as well. Seriously it's the key to an organized life! Here's my favorite one that I highly recommend and have used for years:
The Classic Happy Planner Your Best Year 2020
Seriously I can't say enough how important it is to use a planner whether it's pen and paper or digital to get yourself organized. And of course to actually stay organized in every aspect.
Hope you love the free social media printable calendar as much as I do and it helps you stay on top of your blogs social media accounts. I know it can be overwhelming but by staying consistent your social media accounts can really help you grow your accounts. Which can lead to increased blog views and a better relationship with your audience. Which is a total win-win!
Let me know if you have any questions or want any new social media or blogging tips or advice!
Let's get social!
If you liked this post with a free social media printable calendar for bloggers then you probably (hopefully!) will enjoy these too:
- 365 Blog Post Ideas For 2021 To Grow Your Blog
- 15 Instagram Story Ideas To Grow Your Account
- Before You Post: Blog Post Checklist
- 8 Essential Tips For Setting Blog Goals
- Summer Instagram Challenge: 40 photos edition
Let's stay in touch and really connect!
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Growing up, Ellen always liked and had different types of animals. When her family spent 5 years overseas, they took their animals with them. Before she came to work with us, Ellen and her husband Larry owned a pet store, and Dr. Eisel was their store vet. After they closed the business, Ellen joined the Animalife family and the rest is history. As part of our team, she enjoys developing close relationships with pets and their families by making sure their furry companions are loved and well cared for during their grooming or boarding visits. Outside of the animal hospital, Ellen and her husband run a pet sitting business (Larry is the primary caregiver). A love of pets apparently runs in the family; their 2 children and 3 grandchildren all have multiple pets in their households. Ellen and Larry share their home with 5 different dog breeds, 7 rescued cats, and a Red Foot tortoise named Rosie. In her spare time, Ellen loves reading, traveling with her husband, eating out, and photography.


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Thepolitico-economic interests of states – behind the contemporary combats – totopple unfavorable governments abroad, to seek easy trade deals, to utilizenatural resources across the world and to establish a desired world order makethe modern wars not the holy wars. Holy wars are fought to propagate orsuppress a religion against those are considered as "Enemies of God". Existence of wars canbe traced back to the point when competition and conflict emerged as socialconcepts running parallel with cooperation. Human societies and nations havefought wars on various grounds i.
e. religious, political and economic. The warsfought on religious basis were termed as Holy Wars which are quite differentfrom the Modern Wars being witnessed today. Unlike the Holy Wars, Modern Warsremain considerably political and economic in nature.
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These are not derived byany pure religious rivalry or agenda. According to the Encyclopedia of War, outof all known/recorded historical conflicts, only about 7% had religion as theirprimary cause, and of that percentage, 4% were related to Islam. In severalconflicts including the Israeli–Palestinian conflict,the Syrian civil war, and the wars in Afghanistan and Iraq,religious arguments are overtly present but variously described as fundamentalism or religious extremism depending uponthe observer's sympathies. In Classical Antiquity develops thenotion of a pantheon with a divine"division of labour".
Now, Ares was"war personified", but while Ares received occasional sacrifice fromarmies going to war, there was only a very limited "cult of Ares"While early empirescould be described as henotheistic,i.e. dominated by a single god of the ruling elite or more directly by deifyingthe ruler in an imperial cult,the concept of "Holy War" enters a new phase with the developmentof monotheismIn early Christianity,St. Augustine's concept of just war (bellumiustum) was widely accepted, but warfare was not regarded as a virtuousactivity. According to historian Edward Peters, before the 11th centuryChristians had not developed a concept of "Holy War". During the 9thand 10th centuries, multiple invasions occurred which lead some regions to maketheir own armies to defend themselves and this slowly lead to the emergence ofthe Crusades, the concept of "holy war", and terminology such as"enemies of God" in the 11th century.While technically, themillennium of Muslim conquests could be classified as "religiouswar", the applicability of the term has been questioned. This happenedmany times throughout history, beginning with Muhammad'sbattles against the polytheist Arabsincluding the Battle of Badr (624), andbattles in Uhud(625), Khandaq (627), Mecca (630)and Hunayn (630).
.Religion is one ofthe most sensitive issues and, although every religion encourages the ideaof peace and tolerance, almost no one remains in peace or tolerates anythingwhen it comes to their religion. History is full of religious wars and some ofthem have continued for years and killed many.
The Battle of Badar, fought on 17 Ramadan, 2 AH in the Islamic calendar)in the Hejaz regionof western Arabia,was purely of religious based. Muslims fought against non-believers for thesake of Islam. 14 Muslims were martyred in this battle. Battle of Uhad and Battle of Hind were alsoof religious based and were fought by Muslims against non-believers. The Second War ofKeppel was fought in 1531, in the land of Switzerland as a result of religiousconflicts between Catholic cantons and Protestants.
It was a roughestimate at that time that 7,000 Protestants and 2,000 Catholics fought thiswar and in the end, more than 700 people died including a majority ofcivilians. Lebanese civil war wasvery particular and different from other religious wars, as it was foughtbetween Sunnis and Shiites at the land of Lebanon. Both sides belong todifferent ethnic groups of Islam and they both wanted the government control ofLebanon. The Lebanese Civil War started in 1975 and ended and the end of 1990and it was estimated that more than 150,000 people were killed in theseinter-country conflicts.The Crusades is just acatch-all title for the multiple religious wars and fights that were foughtbetween Muslims and Christians. These wars were due to the religious disputesand controls over land in Jerusalem. The first war started in 1095 and lasteduntil 1097, whereas the second war was started in 1097 and continued till1127. Along with many other wars, it all stopped in 1303 when both war soldiersshed blood of more than half a million civilians in the fight and the controlof that land was given to the Christians.
ThirtyYears' War is a series of religious wars, that was fought in between 1618 to1648 in Europe, and at that time, most of the European countries participatedin these wars. This period of wars is the longest and most demolishing periodof fighting in the history of the world that left more than 800,000 deathsincluding soldiers and civilians. These short period wars were also foughtbetween the religious conflicts in between the Holy Roman Empire, France,Sweden and Spain.Warsbeing fought today are very different from religious wars. "Holy"wars were waged with the objective of achieving religious goals like conqueringholy cities, expanding "holy" empires, etc. But, modern wars are waged bynations to secure their Geo-political interests.
Most nations who have beeninvolved in modern wars are Secular. War inmodern times has been the inclusion of civilians and civilian infrastructure as targets in destroyingthe enemy's ability to engage in war. Modern warfare uses the concepts,methods, and military technology that have come into use during and after World Wars Iand II.Religionhas been the cause of all the major wars in history.
I have heard this textrecited like a mantra by American commentators and psychiatrists, London taxidrivers and Oxford academics. It is an odd remark. Obviously the two World Warswere not fought on account of religion"(KarenArmstrong)Nationstates are indulged in fighting these wars to secure their politico-strategicinterests, to protect their investments, to seek maximum benefits out of othercountries' governments and the trade opportunities available. Besides that, thecombat against terrorism is another idea that overwhelms the Modern Wars thusmaking them apart from the Holy Wars.
Startingwith the politico-strategic interests lying behind the modern wars, it can beclearly noted that the holy wars are totally a different thing. This is theworld of nation-states. Each of these states maintains specific politicalinterests attached with the developments across the globe. There are strategicinterests nourished by the modern nations to have a conducive politicalenvironment in different regions.
Amid these complexities, these nationscooperate when required but also fight wars when desired. Examples of suchmodern wars driven by politico-strategic interests are apparent. TakeU.S-led wars being fought in the Middle Eastern nations of Syria and Iraq.
These wars are not against the religion prevailing in the said region but tosecure strategic leverage and political hold there. U.S.
desires a pro-AmericanMiddle Eastern regime. That's why it topples and installs governments in thename of democracy. All this makes its modern wars different from thetraditional concept of Holy Wars which used to be purely religious likeCrusades.
Another example is thepresence of Russia, Turkey and Iran in the Syrian civil war. These states arepresent and actively engaged in Syrian war to secure their political interestof regional influence, hold and dominance against the United States of America.Thirdly, Saudi Arabia'sfighting against the Houti rebels in Yemen, is not purely of religious causes.Its primary objective is to secure its strategic interests and to contain theexpansion of Iran.
The Saudis believe the Houthis (which are Shia ) are backedby Iran and the Saudis do not want another Iranian proxy army on their southernborder controlling most of Yemen. Second thing thatrenders modern wars separate from the holy wars is economic and commercialarenas of interests. States are engaged in trade within and outsideits borders. Powerful nations tend to secure their economic interests abroadthrough the pacific tools of concessions and aid. But they also revert tocombative measures sometimes for this purpose.
For instance, U.S. is stillensuring its military presence in Iraq not because of fighting any holy combatbut to hold the country's natural resources and exploit the maximum economicbenefit from them. Former president Barak Obama's statement proves it true; "Terrorists werebeing allowed to overrun part of Iraq's territory This poses a danger to Iraqand its people given the nature of theseterrorists, it could pose a threat eventually to American interests aswell." Experts on the regionquestion whether oil, terrorism or anything else justifies U.
S. military actionin Iraq. Similarly, China andthe United States of America are contesting in an undeclared and informalcombat in Africa to control the region's natural resources for the future useand excessive economic value. Africa has long been torn by conflicts driven bysectarian enmities, power struggles, and disputes over colonial borders. Withthe exception of Egypt, the entire continent falls under the purview of the USAfrica Command, or AFRICOM. Established in 2007, AFRICOM was responsible forthe 2011 intervention in Libya that backed the rebellion against the governmentof Col. Moammar al-Gaddafi.
AFRICOM troops have also been involved in fightingIslamist insurgencies in Libya, Mali and Chad in subsequent years. While chinais present there for African diamonds, uranium deposits, rare metals, andfossil fuels. Chinese investors have made substantial inroads into thecontinent in recent decades, negotiating numerous construction projects, miningrights and oil and gas exploration deals. Being the economic rivals, both statesare at war in Africa.
This clearly makes these modern wars differentiated fromthe holy wars which are fought for a religious purpose. In another aspect,modern wars are being fought to have access to the free trade deals and toestablish economic hegemony. That is what has been witnessed in the South-EastAsia in the recent months. US and China have come at daggers drawn to maintainan economic hegemony in the said region.
Southeast Asia, being the home ofAssociation of Southeast Asian Nations (ASEAN) is hub of economic activity.This brings U.S. and China – the two top world powers – in a contention ofmodern nature which is not holy in any way. Lastly, the modern waragainst terrorism makes the contemporary combats different from the holy wars.The latter were fought for propagation or suppression of a religion. This isnot the case with the modern fight on terrorism that is not against anyreligion or religious ideology.
In fact, these are against the thinking ofterror-spreading through excessive use of violence. Modern wars on terrorismbeing fought in Afghanistan, Middle East and to some extent in Europe andAfrica are completely different from what is called as holy war. In such warsthe enemy is murdering humanity. Thus, it makes no sense whether he is a Muslimor a Christian.
Further, it gives him a new identity of a terrorist. Thisjustifies a modern war against him which works not on religious basis but inthe grounds of saving humanity from terror. Operation zarb-e-Azab, OperationAl-Mizan, Operation Rah-haq in Pakistan are the examples of battles beingfought against terrorism but not to suppress or propagate any religion. In conclusion, wars area reality. But they vary in their very nature defined by the agenda beingpursued behind them. When the agenda is religious, they are termed as holy warsand when the agenda became economic, political and strategic; they are calledModern Wars.
Today, the world is experiencing the modern wars which rarely haveanything to do with the religious mindset. Nation states are devising andfighting these wars to ensure the maximum economic benefits for them in theform of favorable trade deals and free trade regimes. Further, the politicalinterests of maintain strategic leverages in various regions enable them toshape their wars with modern mission which would not reflect spirit of anyreligious or holy cause in them but purely material. All this obvious materialapproaches of fighting wars today make them modern without becoming holy.


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Breaking Bad is back—sorta.
Almost four years after the critically acclaimed AMC show about a cancer-stricken chemistry teacher who "breaks bad" and turns to the meth trade left the air, a fan has recut the five-season show into a two-hour movie version available on Vimeo.
Squishing 62 episodes into a two-hour cut is no mean feat, and commenters on Vimeo were right to point out that a lot—specifically of the character arc of Jesse Pinkman—gets cut in this version in favor of a Walt-dominated throughline.
Overall, it does a nice job of weaving a few choice foreshadowing moments and laying some groundwork about the "growth, decay, transformation" that awaits. Crucially, while it takes a different spin on the opening scenes, the show's explosive finale is (perhaps unavoidably) left largely intact. Plus, there are some nice original touches here, like the opening credits that showcase a bit of each character's personality as the actor's name appears atop a well-suited textile swatch.
It's a very smooth edit, technically speaking, but it's immediately clear to old fans of the series that something in the overall arc isn't quite right. Longer snippets of scenes—like the family intervention about chemotherapy—play out more like a best-of montage than a new, tighter storyline. (Personally, I loved the use of "Crapa Pelada" as a meth montage rather than its original appearance in Gail's apartment, but wouldn't it have been easier to cut Gail's arc entirely than to use him for less than 10 minutes?) The accelerated pace is an understandable one, given the time constraints, but it's hard to ignore what's missing when you know the source material.
Gaylor Morestin and Lucas Stoll are far from the first ones to tighten up a massive project into a movie form: Someone recut the Hobbit trilogy into a single film after its release, and another fan combined Captain America and Winter Soldier for a complete look at the backstory. Jason Grzybowski even attempted something similar with Breaking Bad a few years back, but his version was pulled from YouTube.
Bottom line: Look, if you or a loved one lived under a rock between 2008 and 2013 and you desperately need to catch up on the show's high points before you try to hit up the Los Pollos Hermanos pop-up in Austin or watch the new season of Better Call Saul, press play. This is a great homage to an even better show. But if you want to really understand the nuances and heartbreaking cliffhangers of a show widely hailed as one of television's best in recent memory, nothing will top the five-season run of the original cut.
Update 3:52pm CT: Sony's issued a Digital Millennium Copyright Act claim to remove this cut from Vimeo for infringing on its copyright. While fan works are typically regarded as a fair use case, and the creators here put disclaimers left and right acknowledging it wasn't their original footage, it seems this video was destined to be pulled.
H/T Mashable


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The Beauty of Your Face by Safar Mustafah is a compelling and authentic novel that not only explores the complex struggles of a culturally conflicted daughter of Palestinian immigrants, but also touches on universal themes such as identity, loss and the pain of a middle child rejected by her mentally fragile mother.
The book follows dual storylines of Afaf , principal of a Muslim school for girls just outside Chicago, opening with the shocking arrival of a xenophobic shooter who kills girls at random. The eventual tense standoff between Afaf and the shooter frames the more in-depth story of her earlier life leading to this point.
A bright, intelligent teenager, Afaf negotiates the difficulties of life as the daughter of secularized parents in a town where she faces casual but cruel racism on a daily basis. When a tragic loss causes major family upheaval, she struggles to find a place to belong when she's spurned by all her classmates and even her own mother who seems to hate her. She becomes rebellious, experimenting with casual sex and growing to hate herself in the process. When the incidents of 9-11 occur, the racial slurs intensify and her life becomes close to unbearable.
Afaf eventually follows in her beloved father's steps as he becomes a "born again" Muslim and she finally finds a place and people that welcome her. The author, however, avoids cliché and sentimentality by portraying the complexity of a family divided by their level of faith. In other words, religion is not presented as a magic "cure" for the problems of this family.
The story builds to an inevitable climax when Afaf confronts the shooter. The author uses a classic suspense technique and makes us wait until the end to find out the outcome, a good choice because by this time the reader is heavily invested in the pitfalls and victories of Afaf's life.
This was a well written book that provides a window on the struggles of second generation immigrants in a country that often misjudges and even fears them. Afaf is a compelling and sympathetic character whose experiences prove that despite the colour of our skin or our differences in religion we are all still striving for love, happiness, acceptance and a place to call home.
Thanks to Legend Press for sending me a complimentary copy of the book in exchange for an honest review. Check out the other stops on the blog tour to see what others have said about the book.