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Standard of Excellence Book 1 Enhanced, Trumpet PW21TP
by Kjos
Original price $ 10.50 - Original price $ 10.50
Original price $ 10.50
$ 12.99
$ 12.99 - $ 12.99
Current price $ 12.99
The Standard of Excellence ENHANCED Comprehensive Band Method Books 1 and 2 combines a strong performance-centered approach with music theory, music history, ear training, listening, composition, improvisation, and interdisciplinary and multicultural studies. Each book comes with online audio containing all the full band accompaniments and the revolutionary iPAS Practice and Assessment Software. Directors will welcome the complete accompaniments and inspiring software. Students will find the new package makes practicing not only fun but effective, too! The result is the most complete band method available anywhere.


text: Investigates North American urban political geography, exploring conflicts over immigration, environment, gentrification, homelessness, labour market restructuring, 'race' and racism, urban sprawl, nature and environment, gender, sexuality, security, and segregation. Explores competing visions of city life and claims on urban space. The course investigates how these struggles connect to economic, social and environmental politics at larger spatial scales, and considers different theoretical frameworks that geographers have developed to make sense of both the persistence of old problems and the emergence of new ones. Potential field trip, cost: approximately $21.

subset: commoncrawl


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Bad Boys for Life
The wife and son of a Mexican drug lord embark on a vengeful quest to kill all those involved in his trial and imprisonment — including Miami Detective Mike Lowrey. When Mike gets wounded, he teams up with partner Marcus Burnett and AMMO — a special tactical squad — to bring the culprits to justice. But the old-school, wisecracking cops must soon learn to get along with their new elite counterparts if they are to take down the vicious cartel that threatens their lives.
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Directors: Bilall Fallah, Adil El Arbi
Budget: $90 million
Box office: $419.1 million
Berlin Premiere
When: Tuesday 7th January 2020
Where: Zoo Palast, Berlin, Germany
Los Angeles Premiere
When: Tuesday 14th January 2020
Where: TCL Chinese Theatre, Hollywood Blvd, Los Angeles, CA
Fun Facts
Martin Lawrence's daughter, Jasmine has a cameo as one of the two girls who don't let Marcus and Mike into the club.
The release of Bad Boys for Life coincided with the 25th anniversary for Bad Boys (1995).
This film had been in development for over 10 years!
Filming took place in Atlanta, Georgia, Miami, Florida and Mexico City.
DJ Khaled served as the executive producer for the film's soundtrack.


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WhatsApp: +86 17731178606
January 26, 2021
Yoga ball is one of the most common tools for yoga and we can get many benefits from a long-term yoga ball practice. Actually, sticking to yoga ball practice not only can add more fun to our life, but also help us lose weight and burn calories effectively and efficiently. So, next we are going to cover all the advantages of yoga ball practice to bring you more power to insist on yoga ball practice.
1. Yoga Ball is Ideal for All Age Groups
Firstly, yoga ball exercise is a practical movement that is suitable for Men, Women, Children and the Elder, because yoga balls is a relatively and gentle exercise without a lot of impact so that some of the injuries might be avoided.
Some people may be not able to do sit-ups because of back injuries. However, you can do it or even some more challenging moves using a soft yoga ball during yoga ball exercise. It will work well as a cushioning to buffer the pressure of your body and protect your joints and back.
2. Yoga Ball Exercise Helps to Improve the Balance Control of the Body
Previously, most of the body-building movement is performed on the ground or stationary equipment. Therefore, most of us do not have the chance to practice balance control, which is very import for daily living.
Yoga ball is an exercise different from any weight or aerobic training we had before. It push you to stay off the ground to improve your overall body control. For example, sitting on a ball is a balancing exercise. The higher the leg is raised, the more difficult the exercise will become.
When doing push-ups with both legs on the ball, you need to complete a series of movement of flexing and extending arms. Before that, you should maintain the balance of the body and prevent the ball from rolling around. You must rely on the strength of the legs, waist and abdomen to control the whole body, which then will improve the coordination of the body and the ability to control the muscles.
3. Four, yoga ball movement provide great massage therapy.
Most of yoga balls are made of soft but solid PVC materials. When the soft sphere contact with the body, the pressure from your own weight will provide great massage for your deep muscle tissues. More than that, because of its soft construction, it is gentle on sensitive or painful areas of the body, which then improve blood circulation.
4. Correct your sitting posture
When you're sitting on the ball, your body is not totally relaxing. Your muscles in the back, hips, knees, etc., are constantly making subtle adjustments to keep you balanced.
These minor adjustments help to improve overall blood circulation while building up back strength. Through adjusting the body's center of gravity and balance at any time, you increase the spine movement, your back strength, and correct and maintain proper sitting posture.
In a word, yoga ball is an interesting movement that would provide more relief and relaxation for your hot and intensive yoga sessions.
March 17, 2023
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1.15: Exercises
- Page ID
- 17020
Exercise \(\PageIndex{1}\)
Write a function called
is_sorted that takes a list as a parameter and returns
True if the list is sorted in ascending order and
False otherwise. You can assume (as a precondition) that the elements of the list can be compared with the relational operators
>, etc.
For example,
is_sorted([1,2,2]) should return
True and
is_sorted(['b','a']) should return
Exercise \(\PageIndex{2}\)
Two words are anagrams if you can rearrange the letters from one to spell the other. Write a function called
is_anagram that takes two strings and returns
True if they are anagrams.
Exercise \(\PageIndex{3}\)
The (so-called) Birthday Paradox:
- Write a function called
has_duplicatesthat takes a list and returns
Trueif there is any element that appears more than once. It should not modify the original list.
- If there are 23 students in your class, what are the chances that two of you have the same birthday? You can estimate this probability by generating random samples of 23 birthdays and checking for matches. Hint: you can generate random birthdays with the
randintfunction in the
You can read about this problem at http://en.Wikipedia.org/wiki/Birthday_paradox.
- Solution:
Exercise \(\PageIndex{4}\)
Write a function called
remove_duplicates that takes a list and returns a new list with only the unique elements from the original. Hint: they don't have to be in the same order.
Exercise \(\PageIndex{5}\)
Write a function that reads the file
words.txt and builds a list with one element per word. Write two versions of this function, one using the
append method and the other using the idiom
t = t + [x]. Which one takes longer to run? Why?
Hint: use the
time module to measure elapsed time.
- Solution:
Exercise \(\PageIndex{6}\)
To check whether a word is in the word list, you could use the
in operator, but it would be slow because it searches through the words in order.
Because the words are in alphabetical order, we can speed things up with a bisection search (also known as binary search), which is similar to what you do when you look a word up in the dictionary. You start in the middle and check to see whether the word you are looking for comes before the word in the middle of the list. If so, then you search the first half of the list the same way. Otherwise you search the second half.
Either way, you cut the remaining search space in half. If the word list has 113,809 words, it will take about 17 steps to find the word or conclude that it's not there.
Write a function called
bisect that takes a sorted list and a target value and returns the index of the value in the list, if it's there, or
None if it's not.
Or you could read the documentation of the
bisect module and use that!
- Solution:
Exercise \(\PageIndex{7}\)
Two words are a "reverse pair" if each is the reverse of the other. Write a program that finds all the reverse pairs in the word list.
Exercise \(\PageIndex{8}\)
Two words "interlock" if taking alternating letters from each forms a new word. For example, "shoe" and "cold" interlock to form "schooled."
- Write a program that finds all pairs of words that interlock. Hint: don't enumerate all pairs!
- Can you find any words that are three-way interlocked; that is, every third letter forms a word, starting from the first, second or third?
Credit: This exercise is inspired by an example at http://puzzlers.org.
- Solution:


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As expected, Oh Ji-hwan (33) remained at LG. He disappeared from the next free agent market as he signed a multi-year contract with LG early, leaving one year to reacquire free agency.
On the 19th, Oh Ji-hwan agreed to a multi-year contract with LG from 2024 to 2029 for a total of 12.4 billion won over 6 years. With a guarantee of 10 billion won and an option of 2.4 billion won, the highest amount among all shortstops in the KBO League. It is the largest contract in the history of the LG club.
Oh Ji-hwan, who remained at LG with a 4-year, 4 billion won free agent contract in December 2019, was scheduled to reacquire free agency after this season. However, since last winter, multi-year contracts have been popular in the KBO league, and LG has also formed a consensus with Oh Ji-hwan early. An agreement was reached before leaving spring camp. Oh Ji-hwan was put down with a contract that was more than three times bigger than the free agency. 먹튀검증
As expected, with Oh Ji-hwan effectively signing a 'life contract' with LG, the atmosphere for the next free agent market will be somewhat bleak. It is evaluated as a market that already lacks special free agents, but since the largest fish has disappeared, the possibility of the market temperature cooling has increased. A different atmosphere is expected from the FA market, which has heated up over the past three years.
Players who can qualify for FA after this season are pitchers Lim Chang-min (Kiwoom), Lim Chan-gyu, Jin Hae-su, Ham Deok-joo (LG), Kim Jae-yoon, Ju Kwon (KT), Shim Chang-min (NC), Kim Dae-woo, Oh Seung-hwan (Samsung), Kangryul Kim, Gunhee Hong (Doosan), Minjae Jang, Wooram Jeong (Hanhwa), catcher Minshik Kim, Jaewon Lee (SSG), Jiyoung Lee (Kiwoom), Taegun Kim (Samsung), infielders Geonchang Seo, Minseong Kim (LG), Sunbin Kim (KIA) , Kang Han-ul (Samsung), Yang Seok-hwan (Doosan), Ahn Chi-hong (Lotte), outfielder Lee Yong-kyu (Kiwoom), Kim Heon-gon (Samsung), Jeon Jun-woo (Lotte), and Noh Soo-gwang (Hanwha).
There are plenty of free agents for each position, but there are many veterans in their mid-30s, so it is questionable how many will apply for qualification. This winter, Yang Eui-ji (Doosan), Park Min-woo (NC), Chae Eun-seong (Hanwha), Yoo Kang-nam (Lotte), Park Dong-won (KIA), and Noh Jin-hyeok (Lotte) do not appear as prominent free agents. The biggest word to win contracts worth more than 10 billion won over the past two years is even less visible.
It's not like it's just a cold wind blowing. There are certainly notable free agents. On the pitcher side, Kim Jae-yoon with 137 saves and sovereignty with 105 holds draw attention. In particular, Ju Kwon is 28 years old, the youngest among pitchers. As a fielder, Yang Seok-hwan, who has used Jamsil Stadium as his home for the last two years in a row and has hit more than 20 homers, deserves to be called the greatest player.
The competitiveness of requalified free agents has not yet died. It is noteworthy whether Ahn Chi-hong, who transferred to Lotte after winning the highest contract for 2+2 years at 5.6 billion won in the FA market 4 years ago in the cold wind, will sign more contracts. After renewing the contract with Lotte for 4 years and 3.4 billion won, I wonder how Jeon Jun-woo, who was re-evaluated as the best free agent in terms of cost performance, will be treated.


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tag:blogger.com,1999:blog-2595796005864296724.post1257806958865660041..comments2023-03-02T05:23:00.426-08:00Comments on Eat Their Words: The Very Hungry Caterpillar - Hungry Caterpillar Fruit SaladKatie Frieshttp://firstname.lastname@example.com:blogger.com,1999:blog-2595796005864296724.post-971165129888572612010-07-15T09:26:40.672-07:002010-07-15T09:26:40.672-07:00Callie, no problem! Link away! Thank you! Hope you...Callie, no problem! Link away! Thank you! Hope your fruit salad was delicious.Katie Frieshttps://firstname.lastname@example.com:blogger.com,1999:blog-2595796005864296724.post-57754366794140136322010-07-15T03:41:21.128-07:002010-07-15T03:41:21.128-07:00Hi Katie! Thanks for the kind words about my blog!...Hi Katie!
Thanks for the kind words about my blog! I think yours is adorable! What a great idea to pair books with recipes! Can I put this blog on my blogroll? And yes, feel free to link to my blog as well. I think I'll be making a fruit salad for breakfast while we read The Very Hungry Caterpillar! Nice to meet you! :)calliefeyenhttp://email@example.com:blogger.com,1999:blog-2595796005864296724.post-27806925043825171152010-07-13T09:24:16.705-07:002010-07-13T09:24:16.705-07:00That's a great idea, Sandhya! I have a friend ...That's a great idea, Sandhya! I have a friend who talks about "growing foods" with he daughter--sounds like this book fits in well with that concept. Glad this post brought back some fun memories for you.Katie Frieshttps://email@example.com:blogger.com,1999:blog-2595796005864296724.post-56339361081569428232010-07-13T05:09:40.608-07:002010-07-13T05:09:40.608-07:00Eric Carle rocks! And 'The very hungry caterpi...Eric Carle rocks! And 'The very hungry caterpillar' has been used by me in another way. A eats like a sparrow, and I would often worry that she did not eat enough. We have this book since she was one, and I would point out to the large amount that the caterpillar ate. She would be fascinated with it turning into a butterfly, and would readily eat more, just as it did. On days when she was hungry home from school, she would say,'today I think I want to eat like that caterpillar'. Your post has made me remember all that. Thanks.
And LOL! The word for verification that has come up is co-incidentally 'hogin'!sandhyahttps://firstname.lastname@example.com:blogger.com,1999:blog-2595796005864296724.post-17687061732874390522010-07-12T16:05:42.040-07:002010-07-12T16:05:42.040-07:00Isn't it fun to create a recipe based on a boo...Isn't it fun to create a recipe based on a book! Next week on my blog your boys might want to check out Recipe Wednesday for the Up, Down, and Around Salad based on the book by Katherine Ayers.Mary Ann Dameshttp://email@example.com


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About World Vision World Vision is a relief, development and advocacy organization working to create lasting change in the lives of children, families and communities to overcome poverty and injustice. Inspired by our Christian values, World Vision is dedicated to working with the world's most vulnerable people regardless of religion, race, ethnicity or gender. For more information, visit www.worldvision.ca or follow us on Twitter, Facebook, Instagram and LinkedIn.
The Barrett Family Foundation is donating $25 million to World Vision Canada to expand a program that improves the lives of vulnerable youth in Latin America by offering them a better and brighter future through education.
The Barrett family, through The...


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AWS Certificate Manager (ACM) is a service from AWS which provide the free on-demand TLS certificate. It's similar to the Let's Encrypt which provide the free cert for you, but the difference is that Amazon controls the Certificate Authority (Amazon Trust Services, LLC) behind the certificates, as well as the accompanying API to manage them.
Unlike Let's Encrypt, you may copy the cert into anywhere as per you like, the only bad thing about the ACM is that you can only associate with the 3 services in AWS which is ELB and ALB, CloudFront distribution and API Gateway endpoints only.
Create certificate in ACM console
To create the new cert, you may login to your AWS ACM console, click on request cert, enter the domain name that you want to create the certificate for, add any additional domain name for your cert if you like to.
Select the DNS validation for your cert as this is a simple way of validate your domain, if you using email validation, it will involve more manual step compare to the DNS validation.
Once everything is confirmed after review, you will get the verification cname entry for you to enter into your DNS server.
After that you may go to your DNS server to configure the Cname for the verification purpose, I'm using Cloudflare as my DNS server, so I need to login to my Cloudflare account and enter the cname and target as per given.
Once the DNS entry has been update and it may take some time to get validate, maybe few minutes to hours, it's depend on the dns propagation time.
To double check the status, you may always refresh on your ACM console page, if the status showing Issued, it's mean that your cert created successfully, you may start to associate it with your resources.
It's easy for you to create and manage 1 – 2 cert using the console, but if you may need to manage more cert or may need to add on the domain into your cert, you will find it very troublesome. As ACM is not support the adding of new domain into your existing SNI cert, you may need to create a new cert which include the existing and the new domain that you wish to add into the cert.
To simplify this task, it's better that we manage it in terraform using code, which can reduce the mistake where we may miss out any old domain in the cert when we create a new cert.
Create certificate using Terraform
To create the cert using terraform, you may need to install the AWS cli and terraform in your machine before you start.
Create a file main.tf in your working directory and enter the following code.
provider "aws" {
region = "us-east-2"
variable "Domain" {
default = "tech.david-cheong.com"
variable "AddionalDomain" {
type = list(string)
default = ["tech-cdn.david-cheong.com"]
resource "aws_acm_certificate" "cert" {
domain_name = var.Domain
subject_alternative_names = var.AddionalDomain
validation_method = "DNS"
tags = {
Name = "Tech Sharing"
Environment = "Production"
CreatedTime = timestamp()
lifecycle {
create_before_destroy = true
output "certvalidate" {
value = aws_acm_certificate.dicefe.domain_validation_options.*
In the script above, basically I set my AWS region to us-east-2 (Ohio) for demo purpose, the create 2 variable (Domain, AddionalDomain).
Next, create the certificate by supply the main domain name and addition name name using the variables, create the tags for the certificate and also lifecycle to make sure the new cert created before it's destroy the existing.
At the end of the script, I output the Cname which I need to use to create the Cname record in my DNS server.
Once the script is save, you need to first initialise the terraform to download all necessary module by using terraform init.
Once the terraform being initialise, you may start to apply the change on AWS. To apply the change, just enter terraform apply –auto-approve to start the process, after the certificate request created successfully, you will get the cname record detail as the output.
You may check on your AWS ACM console, you should see the cert request is created and pending for validation.
Go to your DNS server page, for my case is Cloudflare to enter the cname record given.
After the domain being validated, you should see your cert is ready in the console. Just as simple as that.
By using Terraform, you can easily manage any new domain you wish to add to your existing cert by just enter the name domain in the AddionalDomain variable, than apply it again, get the Cname record to enter into your DNS, than everything should work.
You can delete the cert created using the terraform by using terraform destroy, even the cert if free but just to clean up my AWS account, I just delete it.
Please note that to use the AWS issued certificate with Cloudfront, the certificate must be created in N.Virginia (US-East-1) region, if not, you can't see the certificate from the Cloudfront selection box.
For more detail, you may refer to HashiCorp Terraform documentation at https://www.terraform.io/docs/providers/aws/r/acm_certificate.html
Additional Note:
After being sometime using the Terraform to deploy the cert in AWS ACM, found out that there is an know issue which happen on the AWS SDK, when you have more than 1 alternative name in the same certificate, even you are not updating the certificate, but AWS will randomly change the sequence of subject alternative name (SAN) which lead to the cert need to redeployed.
After spending some time to looking for the solution, there's not actual solution on this, but only a workaround which can prevent your certificate to be deployed by adding "ignore_changes". The sample code as per following. Please note that after add the ignore_changes, every time you want to add any new subject alternative name, than you have to commend up this line, after that un-commend it again to avoid being deployed again and again.
resource "aws_acm_certificate" "cert" {
domain_name = var.Domain
subject_alternative_names = var.AddionalDomain
validation_method = "DNS"
tags = {
Name = "Tech Sharing"
Environment = "Production"
CreatedTime = timestamp()
lifecycle {
ignore_changes = [subject_alternative_names]
create_before_destroy = true


text:
Small business owners are so busy shoveling coal and doing the work of the business that this glimmer of a long-term vision they have for the business hardly gets any light.
If you have some idea of where you want your business to be in a year, in five years, some day, I say put it out there for the world to see. Let your clients and prospects know your ultimate goal – even if you have no idea how you will achieve it.
What I have found is that quite often the world will conspire to help you reach where you are headed, but only if you make it known. One of the most compelling things about being a small business is this notion of clients and networks coming together to help each other be something greater. It's what makes your story so worth hearing.
I'm way guilty of the "ready, shoot, aim" school of business, but very often when I share where I want to go with Duct Tape Marketing, people start showing up with a shovel in hand. So put it out there. Tell me where you want to go.
Sidebar: I guess I should practice what I preach!
- In the next few weeks I am launching a comprehensive, 12-week teleseminar series titled – The Ultimate Small Business Marketing Journey. In this series, small business owners will meet with me via teleconference and learn how to create a killer small business marketing system.
- In the next few months I will release a book, via a major publisher, called, what else, Duct Tape Marketing
- In the next year, I will package the Duct Tape Marketing System and make it available for licensing to small business marketing coaches, writers, pr specialists and consultants worldwide – a business in a box with me as the trainer.
So, there you have it – tell me what you think and stay tuned!


text:
Small Firm - Nationwide Reach
Based in Kansas City, with deep roots in the community, Beckett & Hensley, L.C. has earned a local and national reputation for innovative, strategic thinking and proven results. Over our 25-year history we have provided superior client service to a diverse client base. The Firm is "A-V Rated" by Martindale-Hubbell, which is the highest rating given by the publication. Principals Ted Beckett and Jeff Hensley have provided sophisticated trial skills, committed advocacy and common-sense guidance in the representation of clients from all walks of life and business.
The attorneys at Beckett & Hensley, L.C. have been recognized locally, regionally and nationally by their peers in the legal profession. They have handled hundreds of jury trials, bench trials and arbitrations in Kansas City and in jurisdictions all over the United States.
Request Your No-Cost Consultation
Call us Today
Email us Today


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Climb & Mountaineer Rock Climbing Director and Instructors
Job Description
Are you looking for a fun and rewarding summer job? Do you love working with kids? Are you excited about the outdoors, teaching kindness, cooking, arts and crafts, rock climbing, canoeing, hiking, horseback riding, sports, telling stories, and being creative? Do you dream of spending the summer in the mountains, star gazing, laughing with true friends and having the best summer of your life? If so, we hope you'll apply to join our team at Eagle's Nest for the summer of 2023!
Who We Are: Eagle's Nest Camp is located on 200 acres of wooded land in the lush mountains of Western North Carolina just southwest of Asheville and down the road from Pisgah National Forest. Eagle's Nest provides a joyful, inclusive community where campers finishing kindergarten – 11th grade are treated with respect and compassion. Campers have the opportunity to participate in 1-3 week long sessions which emphasize nature, arts, and community living while taking visual and performing arts, athletic and outdoor classes. Eagle's Nest is an independent non-profit organization. We also host an outdoor adventure program for teens giving them the opportunity to spend two – three weeks backpacking, rock climbing and white water canoeing in North Carolina, across the country, and internationally.
Responsibilities: The Rock Climbing Director is responsible for mentoring the climbing staff (3-4 people), overseeing the progression of classes, and coordinating trip logistics with the Outdoor Program Manager and health staff. In the field, they oversee the safety of the rock site and typically serve as the lead climber for setup and breakdown, in addition to providing instruction. All climbing staff are responsible for planning and leading rock-climbing expeditions in Western North Carolina for young climbers ranging from beginning to advanced skill levels. You will teach campers techniques and skills to maximize their enjoyment of climbing and improve their abilities. Beginning climbers will be introduced to all aspects of climbing and advanced campers can progress to multi-pitch routes and mock leading. The climbing program utilizes our climbing tower, as well as many local natural climbing areas including Looking Glass, Cedar Rock, Linville Gorge, and Rumbling Bald. Our summer staff teach classes every day in areas reflecting their expertise and interests. We also offer classes including, but not limited to, Arts and Crafts, Backpacking, Horseback Riding, Whitewater Canoeing, Rock Climbing, Athletics, Swimming, Music, and Drama.
Required Qualifications: The Rock Climbing Head must be at least 21-years-old and have Experience in traditional rock climbing techniques and teaching. Ability to lead 5.7 trad. CPR and Wilderness First Aid Certifications. Climbing staff must be at least 18-years-old and have one year out of high school.
Preferred Qualifications: Ability to lead 5.9 trad. AMGA or PCIA certification. required; Wilderness First Responder or higher certification.
Benefits: Competitive salary and one full day off each week. On campus housing, delicious healthy meals (including vegetarian, vegan and gluten free options), extensive professional discounts, staff lounge with wifi and access to laundry facilities provided.
Dates: Position late May to August 14th, 2023.
How to ApplyHow to Apply: Please visit our staff webpage to learn more and apply. You can also email us at email@example.com or call Paige Lester-Niles at 336-761-1040. Eagle's Nest Camp is seeking an enthusiastic, experienced climber to head up our rock-climbing wilderness program for the summer of 2023!
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text:
Assignment: Respond to the fellow classmate\'s forum response as if you are a classmate giving your positive/negative opinions/views of their post. USE THE UPLOADED MATERIAL FOR RESPONSE EXAMPLES. Their instructions for their post from the professor are in the following parenthesis: \"Describe how you will integrate media literacy into your teaching classroom and add how you\'d apply the six facets of understanding i.e. explanation, interpretation, application, perspective, empathy and self-knowledge.\"Peer Student\'s Post for Critique by Media Classroom/J. Yeater .: I think its safe to say that in today's modern world of technology, we have become accustomed to being exposed to many different technologically advanced electronic devices that provide more than just entertainment; for instance computers and the world wide web offering practically an endless search capability, as well as access to books, games, and many other learning tools that can be beneficial to young minds. Curriculum based solely on textbooks is not technically "a thing of the past", our society has just undergone significant changes over the years and has made available to us many beneficial resources that promote a healthier learning environment by increasing the motivation to learn, think, and understand what is being taught, and the message being relayed; whether from a textbook, television, or the internet or advertisements. It is frightening to see what is freely available to us and how easily anything can be intentionally presented in an inappropriate manner and not recognized as inappropriate by many as their interpretations of it may not be the same as what it truly is intended to mean. Our younger generations have access too and are susceptible to various media messages that may or may not be appropriate at their maturity level. Our ability to comprehend and fully understand a message, whether it is from a book or by some electronic or visual means, falls within the category of literacy. Media literacy is just that, our understanding of the material from a source outside of a standard textbook. As our classrooms continue to undergo changes, so do the interpretations of the learning concepts and how we define them. There has been various definitions come about in regards to media literacy. The following are from this weeks reading and were published seven years apart, but portray a similar definition of the term media literacy. The Alliance for a Media Literate America termed media literacy as, " media literacy empowers people to be both critical thinkers and creative producers", and "communication technologies transform society, they impact our understanding of ourselves, our communities, and our diverse cultures." (Jacobs, pg141) The Partnership for 21st Century Skills peeled back the onion a little further and described media literacy as, "understanding both how and why messages are constructed and for what purpose, and how individuals interpret the message differently and how it can influence beliefs and behaviors." Overall, media literacy can provide a more positive and enjoyable learning environment by encouraging creativity and critical thinking in order to reach the established learning standards. In order to incorporate media literacy into the classroom, teachers must first learn the culture of the generation they are dealing with. One of the biggest challenges to overcome is that teachers must first ensure they can distinguish themselves the good from the bad and what it is that will both encourage critical thinking and keep the students interest along the way in order to reach the established goal of understanding. One subject in particular caught my eye as I was reading, health education. This subject matter is everywhere you look and go, plastered on billboards, clothing, television, magazines, and readily accessible throughout the Internet.
Author: custom-essay
Three Lab Exercises
Lab 1:
This is a Lab exercise consisting of eight questions, and you don\'t need to find any outside sources at all.
There are 8 problems in total, and they have different instructions, please follow the instructions on the worksheet and below:
#1: Follow the instruction on the worksheet
#2a,2b,2c: convert the quantities and make sure to show your steps
#3: Make sure to show your steps
#4a: Use the data to answer to question and make sure to show your steps
#4b: show your steps and make a conclusion in few sentences
#5a,5b: include an explanation in your answers
#6a,6b,6c: draw the lines by following the instructions and attach the pics to a doc (it will be better if you can print out the page and draw, then scan the page to the doc after drawing)
#7: follow the instructions on the paper
#8: follow the instructions on the paper
This is a link for you to draw isobar if you don\'t know how.
Lab 3:
This is a Lab exercise consisting of nine questions, and you don\'t need to find any outside sources at all. Make sure to show your steps in any calculations.
#1: you can use excel to graph
#2: The correct answers are:City A-Dallas, City B-Minneaplis, City C-Seattle, City B-Miami, please briefly explain why for each in few sentences.
#3: You can skip this question
#4a: draw the isotherms on figure 3.35 and attach it
#4b,#4c: answer in few sentences
#5: The correct answer are: first one is Omaha, second is New York and the last one is Eureka, briefly explain why for each.
#6: follow the instructions on the worksheet
#7: follow the instructions on the worksheet
#8: follow the instructions on the worksheet
#9: skip this question
#10: follow the instructions on the worksheet
Lab 6:
This is a Lab exercise consisting of nine questions, and you don\'t need to find any outside sources at all. Make sure to show your steps in any calculations.
#1: follow the instructions on the worksheet
#2:draw on two isobars in figure 6.41
#3:make sure to show your steps
#4: follow the instructions on the worksheet and answer the question for each in few sentences
#5: follow the instructions on the worksheet
#6: follow the instructions on the worksheet
#7: follow the instructions on the worksheet
#8: follow the instructions on the worksheet
#9: follow the instructions on the worksheet
#10: skip this problem
Science Based Op-Ed on Why people judge others
For this assignment, you will write a 750 word science-based op-ed that brings relevant psychological research to bear on an important social problem. Students are informed that, although op-eds come in many forms, the best papers share several key features: They identify a specific puzzle (e.g., Why are U.S. obesity rates increasing?), examine the problem in light of current scientific thinking (theory) and evidence (e.g., research findings), and communicate some novel insight about the nature of the problem or propose a solution based on available evidence. You are required to use three or more external sources beyond course readings to support their arguments. For each argument you make, you should cite at least one source to support your claims (e.g., studies show that one's social networks influence whether a person is obese or of normal weight"). Make sure to cite your sources both in the paper (when appropriate, e.g., Brown, 2011) and at the end of the paper as "references." However, be careful that you don't fall into the trap of simply repeating or quoting what another person has said. Use the information and sources you find to bolster your argument.
Acquisition Support and Risk Analysis Effects on Information Security
As an expert in health informatics and health information systems, you have been contacted buta rural hospital to investigate a programming error.Due to a programming error, 19 members of a large healthcare organization received e-mailmessages containing private healthcare information about multiple other members. A root causeanalysis showed that organizational issues played a significant role in this security breach.You will discuss how the Risk Analysis and Management processes described are applied tothis caseIn addition to this, the CIO and stakeholders of the rural hospital are discussing the possibleacquisition of their organization by a large healthcare provider. One reason for the acquisition isthat the facility needs the technology updates to provide quality care; however, there are limitedfunds to obtain the products needed.The hospital is aware of the immediate need to invest in an electronic medical record system.This will be a significant investment, and not all of the organization's stakeholders are on boardwith the purchase. The CIO asks you to write a report that supports the purchase of the EMRsystem.Review the administrative safeguard section, beginning on page 259. Create a 5-6 page paperthat discusses how the Risk Analysis and Management processes described are applied to thiscase. Additionally you are to defend the value of EHR purchase. In your defense, cite at leastthree points that defend the purchase. Use the information obtained from our textbook and internet searches to complete your post. Do not forget to cite your sources following APAformatting principles.
How to perform better and reduce stress?
First: Chose Tope is How to perform better and reduce stress?Please choose one topic from the above list.Second: Make sure you discuss the information technology, the technology tools and possibilities and its usage within your topic of choice.Third: Your paper will be 4-5 pages.Please go to the following URL to learn about research paper writing https://owl.english.purdue.edu/owl/resource/658/01/


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By Global News Global News
Published November 22, 2019
13 min read
Dec. 6, 2019 marks 30 years since the attack at École Polytechnique. On that day, in 1989, a man determined to kill feminists took the lives of 14 women.
He killed: Geneviève Bergeron, Hélène Colgan, Nathalie Croteau, Barbara Daigneault, Anne-Marie Edward, Maud Haviernick, Barbara Klucznik-Widajewicz, Maryse Laganière, Maryse Leclair, Anne-Marie Lemay, Sonia Pelletier, Michèle Richard, Annie St-Arneault and Annie Turcotte.
"We cannot forget," said Bergeron's sister, Catherine.
"Remembering what happened makes us more vigilant."
Annie St-Arneault was curious, meticulous, intensely caring and always searching for adventures of her own making.
St-Arneault, the only daughter and youngest of three children, was 23 when she was killed while attending what was to be her final class before graduating from mechanical engineering studies.
She was trying to figure out whether she wanted to take a job at an aluminium smelter or travel to Africa to join her brother, who worked there as a missionary.
St-Arneault wanted to make the world a better place. She wrote poetry and liked to build things by hand. Her childhood best friend remembers one particular Grade 4 project, painstakingly crafted through many recesses.
"She glued grains of rice one by one to make a clown figure," says Sonia Beauregard, her friend. "When her clown was finished, it was fabulous."
Like Annie Turcotte, who was also killed in the massacre, St-Arneault had a passion for the environment. Once, she came up with the idea of a play with the theme "What can we do to stop pollution?"
For the first four years after she died, people would gather in La Tuque, Que., to read St-Arneault's poetry.
— Jane Gerster
Hélène Colgan was 23 years old in early December 1989, just weeks shy of a planned trip somewhere warm with her friends to ring in the new year. It would have been a well-deserved rest, according to her father.
Colgan was a strong student at the tail end of a degree in mechanical engineering, Clarence Colgan told the Montreal Gazette shortly after the massacre. "She was a conscientious and patient girl and always pushed things through to the end," said Clarence.
She was always juggling "so many projects," but her hard work bore fruit: Colgan was weighing three job offers at the time she was killed, although she was leaning towards one in Toronto.
"She wanted to go to the farthest limits of life. She had so much ambition and hope," Clarence said. "I don't even want to think what she could have done."
Colgan's best friend, Nathalie Croteau, was also among the 14 women killed.
— Jane Gerster
Nathalie Croteau was outgoing and enterprising with a passion for learning, particularly when it came to science.
Croteau was 23 when she was killed, just a couple of weeks shy of celebrating New Year's Eve in the hot sun in Cancun, Mexico with her close friends, Hélène Colgan included.
"Twenty-three years aimed at graduating with a degree. She's only three months away from getting it and she's killed — all because she was sitting in a chair in a classroom," her father Fernand Croteau told the Montreal Gazette shortly after the massacre.
He was so filled with rage at the loss of his daughter, he told the newspaper, he took it out on the walls of his home in Brossard.
— Jigar Patel
Barbara Daigneault was not someone bound by conventional limits.
When she was just seven years old, she asked why she could never become pope. She would ultimately follow in her father's footsteps and study engineering.
While she was at École Polytechnique, Daigneault worked as a teaching assistant for her father, Pierre-Alain Daigneault, a mechanical engineering professor at the Université du Québec à Montréal. At 22, with just one term to go before graduating as an engineer, she was already thinking about her career prospects.
Daigneault had visited professor Adrian Cernea a few times to seek his advice. He was one of the teachers in the classroom at the time of the attack.
"She was a marvelous girl, very nice, very smart," Cernea told the Montreal Gazette shortly after the attack.
Her life as a student was what you might expect: sharing photocopies of class notes, chatting over cups of coffee, and meeting for lunch with friends. She loved shrimp omelettes and chocolate cake with whipped cream.
Her mother named her after a poem by Jacques Prévert, which Lawrence Ferlinghetti translated into English:
Remember Barbara /
It rained all day on Brest that day /
And you walked smiling /
Flushed enraptured streaming-wet /
In the rain
— Drew Hasselback
Anne-Marie Edward loved skiing — a sport she did at school and with her family.
A neighbour told the Montreal Gazette they often saw her and her family bundle into the car to hit the slopes.
It was so near to Edward's heart that she was buried in her school team ski jacket, and her teammates from the Université de Montréal downhill ski team wore patches with her initials on their uniforms after her death.
But the 21-year-old from Pierrefonds was known to love all sports, including the more extreme ones, like white water rafting and rock climbing. She loved to take on any challenge she could, even if she wasn't the most successful — like the time she tried sailing and capsized the family boat 56 times in a row.
Edward was studying chemical engineering at the school and was known for being clever and stubborn.
In 2014, her mother told La Presse that Edward would be proud to see her memory being used to end misogyny.
— Rebecca Joseph
Geneviève Bergeron was a second-year civil engineering student who celebrated her 21st birthday two weeks before she was killed.
She was smart enough to earn a scholarship but also talented enough that she was still vacillating between a career in engineering and one in music. Bergeron played clarinet and sang in the choir at the Montreal Symphony Orchestra.
"She loved to sing," her mother, Thérèse Daviau, told the Montreal Gazette shortly after the massacre. "It's a rare combination of interests."
When Bergeron wasn't studying or singing, she was swimming, playing basketball or babysitting Montreal Mayor Jean Doré's youngest child (as a teenager, Bergeron had helped Doré campaign to win his first council seat).
"Geneviève was sweet, generous and bubbling with life," Daviau said shortly after Bergeron's death. "She was a real ball of fire and a total woman."
— Jane Gerster
Maud Haviernick was, first and foremost, an artist.
The 29-year-old had a bachelor's degree in environmental design and started out her working life as an interior designer, creating habitats for community living.
She chose to go back to school at École Polytechnique to fulfil her dream of being an engineer and studying materials engineering.
She's described as a go-getter who gave any pursuit she took on her all — her mantra was, "If you feel like going all the way, well, just do it."
Haviernick lived with her partner, Serges Gagnon. Their home in Sainte-Rose had a room dedicated to her creative hobbies, which included sculpture. She was killed giving her final presentation for her metals class, along with her classmate, Michèle Richard.
Her sister Sylvie co-founded the December 6th Victims Foundation Against Violence in her memory, along with other people who lost loved ones in the attack.
— Rebecca Joseph
Barbara Klucznik-Widajewicz was outgoing, friendly and had what her husband described as a "great deadpan sarcasm."
Klucznik-Widajewicz was born in Poland. When she was 16, she started dating Witold Widajewicz, her high school sweetheart who became her husband.
Klucznik-Widajewicz was a whiz, studying engineering, economics and food logistics. She was a woman who looked outward, her husband says. She spoke five languages, read a lot — and wasn't shy about sharing what she'd read — and loved to help people.
The couple fled Poland for Germany in 1986 after the country was put under martial law. There, they managed to get an aunt in Quebec to sponsor them. Canada seemed safe, they thought, plus Klucznik-Widajewicz was interested in Québécoise culture. They landed in the spring of 1987.
Klucznik-Widajewicz was 31 years old and in her first year of nursing science at the school when she was killed. The couple was having a cheap meal in the cafeteria when the killer came. Widajewicz survived. He has a daughter now, which makes him anxious.
"Sometimes, I fear she might die if some maniac were to go after her for being too smart or too beautiful," he says.
— Jane Gerster
Anne-Marie Lemay wanted, at least for a little while, to study medicine.
The 22-year-old from Boucherville had wanted to go into health care but ultimately chose to study mechanical engineering, in large part because of a close friend. When she was a teenager, one of Lemay's friends lost the use of his legs.
It was Lemay, known for her ability to connect with people, who visited him weekly to help with his rehabilitation. And it was there that she realized the importance of mechanical devices.
She never dwelled on problems. Lemay was social and played in a band. She was organized and studious. The night before she was killed, she studied all day and then wrote herself an unfortunately prescient note: "Tomorrow is the last day of classes… and of my life, too. Whoa! Now that sounds depressed, at 3 a.m."
Lemay was close friends with Heidi Rathjen, one of the survivors of the massacre, who went on to become an outspoken advocate for gun control.
— Jane Gerster
Maryse Laganière was a shy newlywed with a beautiful smile.
She was the youngest of 14 children raised in Montreal. Laganière, who was 25 when she was killed, was a budget clerk for the school's finance department. That's where she met the "love of her life," Jean-François Larivée, in 1986.
"She was the most beautiful girl I'd ever seen in my life," Larivée told La Presse in 2014.
The couple married in August 1989, and they were working on starting a family. Larivée still believes Laganière was very newly pregnant when she died.
The killer accosted her at the end of her workday, when she had already put on her boots and coat to leave. She tried to fight him and shut the door.
While Larivée has built a life since Laganière's death, he has remained a staunch advocate for gun control. Still, he told La Presse he never got to "where I trusted in life enough to want to bring a child into the world."
— Jane Gerster
Maryse Leclair was a rebel and a go-getter who did not care what people thought of her.
Leclair, a 23-year-old in her fourth year of engineering, had three younger sisters and unabashedly lived life on her own terms.
She liked to listen to British punk and new wave music. For months before she died, she'd been in love with a classmate named Benoit. Together, the couple wanted to study and travel.
The Sunday before the attack, her father, Lt. Pierre Leclair with the Montreal police, had dinner with Benoit. She was wearing a brand-new red sweater purchased specifically for the holidays.
On the night of the attack, the lieutenant spoke to the media outside the school and then went inside and saw the red sweater. Leclair was found dead near the man who killed her.
"We think of our daughter every day," he told La Presse on the 25th anniversary of the attack. "We talk about it often with our other three daughters. It caused us unbearable pain."
— Jigar Patel
Sonia Pelletier was the person who won every competition, secured every scholarship and always beat out others for top of the class.
She was a quiet, undemanding person who grew up with five sisters and two brothers. And yet, her intelligence and liveliness stood out to many. That she was so smart and driven was a source of joy and pride for the Pelletier family and their neighbours in the small, close-knit town of Saint-Ulric.
Pelletier loved rock music, and her favourite song was Gerry Boulet's Toujours vivant (Still Alive). She liked to cook and teach others to cook. One of Pelletier's favourite meals to make was pasta from scratch.
Pelletier was 28 years old and just days from graduating with a degree in mechanical engineering and a transcript of straight As when she was killed.
Despite their loss, her sister Micheline told La Presse the Pelletier family has always thought of the killer's mother.
"We, the families of the victims, had pride in our sisters and daughters. But she had nothing at all."
— Jigar Patel
Michèle Richard, or Mimi, as she was nicknamed, had a brilliant smile and a calming presence.
There was something her friends couldn't quite put their finger on that drew people to her. She was 21 when she was killed, a strong student in her second year of materials engineering.
Richard hailed from Lac-Mégantic, a region she was particularly proud of and returned to once or twice a year to visit her younger sibling, mother and friends. She thought, maybe, she might buy land there one day.
Richard planned to get engaged to her boyfriend, Stéphane, in the spring of 1990. They'd known each other for nearly four years, and he was with her in class when she was shot and killed.
A few days later, Stéphane told a reporter that Richard was "a gentle girl, happy, brilliant, beautiful. She lived every moment intensely. She abhorred violence."
Richard's mother joined other parents following the Montreal Massacre in advocating for stricter gun control.
— Jane Gerster
Annie Turcotte was the youngest of three children, drawn to École Polytechnique because of her older brother Donald. She was gifted, and her intelligence won her a women in science bursary. Turcotte was most interested in metallurgical engineering. In many respects, she was a woman ahead of her time: committed to nature and finding ways to protect the environment.
Despite the seriousness with which she approached her work, Turcotte was lighthearted and a big hit with children. At a summer camp for children with disabilities, Turcotte taught swimming lessons for free. The rest of the year, she gave free lessons to any children staying with their families at the Turcotte family's motel.
"She was amazing with kids," her brother remembers. "We'd go somewhere, and they'd be all over her."
Turcotte was 21 years old when she was killed. On the 25th anniversary of the massacre, her mother told La Presse that despite the years, Turcotte is "forever our darling daughter… We've always kept her very much alive in our house."
— Jane Gerster
WATCH: Why amplifying women's voices in the wake of gender-based violence matters
Approaching the anniversary of the École Polytechnique massacre, a group of reporters at Global News reflected on how we must provide better, more consistent and nuanced coverage of any woman, trans or non-binary person who has experienced violence, abuse or harassment if we are to play a role in eradicating it.
We set out to create Broken, a news project we believe Canada needs. This series will address issues that continue to contribute to and exacerbate gender-based violence. Follow it here.


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"The Eyes of Time helps our players rediscover the world," says Director and Co-Founder Devon Hoffman, "We intersect alternate realities with existing places, opening new spaces of imagination to play in and explore—this changes the way you see reality."
Velarde-based collective The Eyes of Time debuts two new site-specific art installations at form & concept and the Jean Cocteau Cinema. Start the adventure with Unlock the Paradox at form & concept, featuring a series of Paradox Incubators comprising tendrils sprawling across the gallery's front windows. Their physical form is elevated by augmented reality, where viewers are invited to traverse worlds and meet an otherworldly being with a very human problem.
MANIAC Virus transpires at the Jean Cocteau Cinema. Contained within a movie-poster lives a corrupted hard drive harboring a dangerous passenger—the world's first computer virus.There, visitors are, again, able to cross worlds; this time they meet Patient Zero from when the MANIAC Virus bridged the liminal from hardware to humanity.
An interactive zine connects these two experiences with an exploration of the historic corridor.


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The AUD/USD pair returned to the 0.9000 level today after Australia posted better-than-expected jobs data. The pair spent much of late Tuesday and the rest of Wednesday in the 0.8900 zone due to poor Chinese and Australian data, but has since shot up near the 0.9100 zone at the opening of today's Asian session. Australia's unemployment rate came within expectations at 6.0%, but what was surprising was its employment change and its fulltime employment figures. Employment change in February came out at a whopping 47,300 versus the expected 18,000. Fulltime employment during the same month grew by 80,500, while part-time employment fell by 33,200.
The only risks for the pair are the upcoming events in China today (5:30AM GMT), its Industrial Production, Retail Sales, and Urban Investment for January.
The pair is currently trading at 0.9061, with initial resistance seen at 0.9015, followed by 0.9037. Meanwhile, initial support is at 0.8923, followed by 0.8901.
As for the EUR/USD, the pair shot up to the 1.3900 level yesterday, primarily due to the lack of significant events that would affect both currencies. Another probable factor is the circulating rumours that the European Central Bank (ECB) won't raise its cash rates in April. It remains at 2.5%, although the market expects it to return to 2.75% next month.
The pair was hovering between the 1.3840-1.3890 levels on Tuesday and around the opening of yesterday's European session. From there, it rose above the 1.3900 area and peaked at 1.3913, and has since traded within the 1.3900-1.3910 areas. It is currently trading at 1.3900, with initial resistance seen at 1.3870, followed by 1.3905. Meanwhile, initial support is at 1.3824, followed by 1.3789.


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Charles Barkley, former N.B.A. star and present TNT commentator was looking awfully sweaty in his mug shot following his arrest for suspicion of DUI. The New York Daily News reports that Barkley was seen partying with Michael Strahan and actor Jaleeel White prior to his arrest, and he admitted that he was driving to pick up a woman for a sex act prior to his arrest.
Barkley is paid millions for his honest opinions of subjects ranging from sports to racial issues. I can't wait to hear his take on his recent arrest.


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The beach with its fine sand and a sun which accompanies it from sunset to sunrise is surely one of the main attractions that the town reserves for its guests.The costal zone, including the area between the River Conca and the Alberello Canal winds for about 3 km. In this somewhat short space, an open air gym for healthy early morning walks, orderly rows of multicoloured beach umbrellas and sun beds, cutting edge services (lifesaving, first aid and on call medical service, public loud speakers, toilet facilities and a well kept sandy shore etc.), guarantee a safe and restful seaside holiday.
Thanks to the organising structures and the quality of its seawater, the beach and the port of Misano Adriatico have been awarded the Blue Flag several times by the International Committee and the Environmental Board of the European Community Commission. This recognition crowns years of commitment and coherence with regard to environmental politics. Interventions have also recently been carried out to strengthen and improve sewage systems and sewage purification plants which have led to the elimination of draining waste into the sea not only in the entire territory of Misano but also in the upstream municipalities, the first pertaining to the River Conca which today can through special ducts, can channel the waste water into the purification plants adequately empowered in the two costal towns of Misano and Cattolica.
For lovers of boat trips on the open sea and along the coast, it is possible to go on interesting excursion on motor vessels which leave daily from Portoverde, Misano's touristic port. The latter, is without doubt, the most well equipped on the Adriatic coast from the tourist point of view, and boasts every kind of service and installations which make it a residential complex of great prestige.
The climate from April to October is ideal for all ages, with a temperature of about 30° in the months of July and August.


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Clinical Utility of BNP for Monitoring Patients With Chronic HF Treated With Sacubitril-Valsartan
Recently, the novel compound sacubitril-valsartan, an angiotensin receptor neprilysin (NEP) inhibitor, was documented to improve outcomes in patients with systolic heart failure (HF).1 The compound is a salt complex of valsartan and sacubitril, the NEP inhibitor prodrug that is processed in the liver into its active moiety,2 which then interacts with a variety of vasoactive peptides of relevance in HF including enhancing natriuretic peptide (NP) system activity.2 Since its approval for the treatment of chronic HF with reduced ejection fraction, a commonly raised suspicion is that treatment with this new drug may make brain, or B-type, NP (BNP) testing useless for disease monitoring of these patients because sacubitril may interfere with BNP clearance.3 Is it already justified to promote N-terminal- (NT-) proBNP as the gold standard biomarker in HF?3 In this analysis, that hasty hypothesis is critically assessed based on the pathophysiology of NP degradation, the limitations of current NP measurement technologies, and the still-limited published data on the effects of NEP inhibition on NP plasma concentrations in humans. Because the main clinical application of BNP testing currently is and most likely will remain the rule-out of clinically suspected HF, there is no major significant impairment to be expected for BNP testing in daily practice. However, some issues have to be considered when using BNP testing for disease monitoring of patients with chronic HF who are on sacubitril-valsartan treatment.
Pathophysiology of Cardiac BNP and Circulating Forms of proBNP-Derived Peptides in Humans
The family of NPs comprises 3 major forms: atrial, or A-type, NP (ANP), BNP, and C-type NP (CNP). ANP and BNP are key regulators of the body's regulation of volume and blood pressure homeostasis by stimulation of vasodilatation and natriuresis.4-8 ANP and BNP are primarily secreted from the heart in response to increased myocardial stretch mediated by volume or pressure overload; thus, increase in NP can be regarded as markers of "cardiac stress." In contrast to ANP, only limited amounts of BNP are stored in atrial granules, so most BNP secretion requires gene transcription and subsequent peptide synthesis mostly in the ventricles. Figure 1 summarizes our current understanding of BNP synthesis and processing. The initial gene product is pre-proBNP 1-134, which undergoes removal of a 26-amino acid signal peptide in the sarcoplasmatic reticulum during translation, leading to formation of proBNP 1-108. proBNP may be glycosylated post-translation at several sites in its N-terminus to a variable degree.9-11 Subsequently, proBNP is cleaved by prohormone convertases, such as furin and corin, to release the 76-amino acid NT portion NT-proBNP 1-76 and the biologically active C-terminal 32-amino acid molecule BNP 1-32. proBNP is secreted as well, and high concentrations have been reported in blood of patients with HF.10,12 proBNP and NT-proBNP as well as their split products have little to no hormonal activity. Some processing of secreted proBNP (probably by furin) can occur in the blood as well. Although the exact nature and distribution of circulating proBNP-derived molecules in healthy individuals and patients with various cardiac diseases is still uncertain, it has been recognized that both BNP and NT-proBNP are modified into a mixture of various fragments in blood, although intact circulating proBNP, glycosylated NT-proBNP, and glycosylated proBNP have been observed in patients with HF as well.8-15 Only a small portion of BNP circulates as the full-length BNP 1-32, and plasma from patients with HF mainly contains diverse degraded forms truncated from the N- and C-terminal end (e.g., BNP 3-32, 5-31, 8-31, 1-25, 1-26).15
Figure 1: Synthesis, Processing, and Circulating Forms of proBNP-Derived Peptides
The commercially available BNP and NT-proBNP routine assays are immunoassays,8,13 and the antibodies used in BNP assay do not cross-react with NT-proBNP and vice versa. However, both BNP and NT-proBNP assays cross-react with intact proBNP. Immunoreactive BNP and NT-proBNP forms of high and low molecular mass have been described in patients; those forms still need to be better characterized using state-of-the art analytical techniques of proteomics. Depending on the antibodies used, BNP and NT-proBNP assays detect the circulating mixture of BNP and NT-proBNP degradation products to a varying extent; thus, the effects of sacubitril on BNP test results are assay dependent.13,16 Consequently, BNP test results do not reflect the true concentration of the hormonally active BNP in the blood sample.
NP Clearance and Possible Interferences by Sacubitril
NP clearance (Figure 2) occurs by two major mechanisms: enzymatic extracellular degradation by NEP and intracellular degradation by insulin-degrading enzyme, as well as via binding to the NP receptor-C.6 This receptor binds all three forms of the NP family. NEP is a membrane-bound ectoenzyme that cleaves various peptide substrates including insulin beta-chain, beta-amyloid, and various peptide hormones of relevance in HF such as angiotensin II, endothelin-1, bradykinins, substance P, adrenomedullin, calcitonin gene-related peptide, and NPs.6 The combination of sacubitril with valsartan additionally inhibits the renin-angiotensin aldosterone system by blocking angiotensin 1 receptor, which is important because NEP degrades angiotensin II as well. NEP is widely expressed, including the kidneys, lungs, and vascular endothelial cells, and can be released from the cell surface yielding soluble NEP with catalytic activity.17 NEP cleaves ANP and CNP at the cysteine-phenylalanine bond and breaks the ring structure, which eliminates receptor binding. Intact human BNP, by contrast, is a much poorer substrate for NEP, and it is mainly not cleaved at this ring strucure.18 NEP inhibitors have failed to block BNP degradation by human kidney membranes.19 proBNP is resistent to NEP degradation.20 It cross-reacts with commercial BNP assays and has been reported to be the major circulating form detected by BNP assays in patients with chronic HF.12
Figure 2: Clearance of NP With Interference of Sacubitril-Valsartan
Clinical Results: Reported Effects of Sacubitril-Valsartan Treatment on NP Concentrations
Oral NEP inhibitors elevate the NP system activity as assessed by increases in plasma and urine cyclic guanosine monophosphate (cGMP) concentrations in humans.21,22 cGMP is the second messenger of NPs.4,5,7 Oral sacubitril-valsartan treatment leads to a dose-dependent increase in plasma cGMP in healthy human volunteers,21 which provides evidence for an increase in NP system activity.23
In PARADIGM-HF (A Multicenter, Randomized, Double-blind, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality in Patients With Chronic Heart Failure and Reduced Ejection Fraction),1,22 plasma BNP and urinary cGMP concentrations were significantly higher in the sacubitril-valsartan group at 4 weeks and 8 months. This was suggested to reflect apparent NP system augmentation. However, the observed relative average BNP increase was small compared with cGMP increase (on average only about 10 versus 90%, respectively). By contrast, NT-proBNP was significantly lower (average decline of about 30 and 20%, respectively) in the sacubitril-valsartan group. Recently, it was reported that in the patient cohort of the PARADIGM-HF study, patients who attained a reduction of NT-proBNP <1000 ng/L had a lower subsequent rate of cardiovascular death or HF hospitalization independent of the treatment group.24 A similar analysis for BNP in these patients is pending and has not yet been published.
In the earlier PARAMOUNT (Prospective Comparison of ARNI With ARB on Management of Heart Failure With Preserved Ejection Fraction) trial,25 in which sacubitril-valsartan was studied in patients with chronic HF and preserved ejection fraction, there was a significant and greater decline in NT-proBNP (on average about 25%) 12 weeks after treatment compared with valsartan alone. Although there was a rapid (at 4 weeks) and sustained decline in NT-proBNP, the difference between both treatment groups was no longer statistically significant at 36 weeks.24 BNP was not measured in this study. In both studies, however, the reported average BNP and NT-proBNP changes, though statistically significant, were within the known relatively large week-to-week biological variation of these biomarkers.26,27 To date, ANP and NT-proANP or CNP results have not been published in humans taking sacubitril-valsartan.
Implications of Sacubitril-Valsartan for NP Testing in Clinical Practice
Based on the available data on the effects of sacubitril-valsartan on BNP and NT-proBNP, the interpretation of NT-proBNP testing in HF appears to be unaffected by NEP inhibition. However, the relative increases in BNP plasma concentrations reported in the PARADIGM HF trial22 were also only modest (median baseline BNP value was approximately 200 ng/L to a median of about 225 ng/L in the sacubitril-valsartan arm). BNP concentrations >500 ng/L, the frequently used rule-in decision limit for HF,28,29 were rare (75% of BNP concentrations in the sacubitril-valsartan arm were approximately 450 ng/L). The high negative predictive value for exclusion of HF for BNP testing will obviously be maintained in patients with sacubitril-valsartan treatment. After an initial modest rise, which is markedly smaller than in cases of cardiac decompensation, BNP may reach a new steady state during sacubitril-valsartan treatment and then begin to drop long term, if marked clinical improvement occurs. If one wants to use BNP for disease monitoring in these patients, it is advisable to measure BNP about 1 month after start of sacubitril-valsartan treament to obtain a new baseline value for subsequent HF monitoring. By contrast, for disease monitoring of patients with chronic HF on sacubitril-valsartan, the current concept of "the lower the NT-proBNP test result the better the prognosis" will always remain to be true. It was even suggested to use an increase in BNP to define who might respond to sacubitril-valsartan or to assess patient compliance. The potential of the BNP/NT-proBNP ratio for chronic HF monitoring with sacubitril-valsartan remains to be further investigated, and undoubtedly more clinical data are still needed.
- The clinical utility of BNP testing to rule out HF, which will remain its major clinical application in routine use, will not be impaired by sacubitril-valsartan treatment of patients.
- The clinical benefit of BNP or NT-proBNP testing for treatment monitoring or even therapy guidance in patients with HF including patients on sacubitril-valsartan therapy remains to be proven, and routine NP testing is currently still not recommended for this purpose.
- BNP is a poor substrate of NEP, and thus no major effects of NEP inhibition on BNP concentrations are to be expected by NEP inhibitors.
- Available data suggest that the concept "the lower the BNP test result,the better the prognosis of chronic HF patients" may no longer be true for patients during the first weeks of sacubitril-valsartan treatment due to modest BNP increases. Therefore, BNP measurement about 1 month after start of treatment is recommended to obtain a new baseline value for follow-up testing.
- The clinical interpretation of NT-proBNP test results in patients with HF is unaffected by NEP inhibition. The concept "the lower the NT-proBNP test result the better the prognosis of chronic HF" is also valid after start of treatment with sacubitril-valsartan.
- McMurray JJ, Packer M, Desai AS, et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med 2014;371:993-1004.
- Mangiafico S, Costello-Boerrigter LC, Andersen IA, Cataliotti A, Burnett JC Jr. Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics. Eur Heart J 2013;34:886-93c.
- McKie PM, Burnett JC Jr. NT-proBNP: The Gold Standard Biomarker in Heart Failure. J Am Coll Cardiol 2016;68:2437-9.
- Volpe M, Rubattu S, Burnett J Jr. Natriuretic peptides in cardiovascular diseases: current use and perspectives. Eur Heart J 2014;35:419-25.
- Song W, Wang H, Wu Q. Atrial natriuretic peptide in cardiovascular biology and disease (NPPA). Gene 2015;569:1-6.
- Potter LR. Natriuretic peptide metabolism, clearance and degradation. FEBS J 2011;278:1808-17.
- Mair J. Biochemistry of B-type natriuretic peptide--where are we now? Clin Chem Lab Med 2008;46:1507-14.
- Mair J, Lindahl B, Giannitsis E, et al. Will sacubitril-valsartan diminish the clinical utility of B-type natriuretic peptide testing in acute cardiac care? Eur Heart J Acute Cardiovasc Care 2016 Jan 12 [Epub ahead of print].
- Mair J. Clinical significance of pro-B-type natriuretic peptide glycosylation and processing. Clin Chem 2009;55:394-7.
- Hammerer-Lercher A, Halfinger B, Sarg B, et al. Analysis of circulating forms of proBNP and NT-proBNP in patients with severe heart failure. Clin Chem 2008;54:858-65.
- Semenov AG, Postnikov AB, Tamm NN, et al. Processing of pro-brain natriuretic peptide is suppressed by O-glycosylation in the region close to the cleavage site. Clin Chem 2009;55:489-98.
- Costello-Boerrigter LC, Lapp H, Boerrigter G, et al. Secretion of prohormone of B-type natriuretic peptide, proBNP1-108, is increased in heart failure. JACC Heart Fail 2013;3:207-12.
- Semenov AG, Katrukha AG. Analytical Issues with Natriuretic Peptides - has this been Overly Simplified? EJIFCC 2016;27:189-207.
- Seferian KR, Tamm NN, Semenov AG, et al. Immunodetection of glycosylated NT-proBNP circulating in human blood. Clin Chem 2008;54:866-73.
- Niederkofler EE, Kiernan UA, O`Rear J, et al. Detection of endogenous B-type natriuretic peptide at very low concentrations in patients with heart failure. Circ Heart Fail 2008;1:258-64.
- Luckenbill KN, Christenson RH, Jaffe AS, et al. Cross-reactivity of BNP, NT-proBNP, and proBNP in commercial BNP and NT-proBNP assays: preliminary observations from the IFCC Committee for Standardization of Markers of Cardiac Damage. Clin Chem 2008;54:619-21.
- Vodovar N, Séronde MF, Laribi S, et al. Elevated Plasma B-Type Natriuretic Peptide Concentrations Directly Inhibit Circulating Neprilysin Activity in Heart Failure. JACC Heart Fail 2015;3:629-36.
- Pankow K, Schwiebs A, Becker M, Siems WE, Krause G, Walther T. Structural substrate conditions required for neutral endopeptidase-mediated natriuretic Peptide degradation. J Mol Biol 2009;393:496-503.
- Watanabe Y, Nakajima K, Shimamori Y, Fujimoto Y. Comparison of the hydrolysis of the three types of natriuretic peptides by human kidney neutral endopeptidase 24.11. Biochem Mol Med 1997;61:47-51.
- Semenov AG, Katrukha AG. Different Susceptibility of B-Type Natriuretic Peptide (BNP) and BNP Precursor (proBNP) to Cleavage by Neprilysin: The N-Terminal Part Does Matter. Clin Chem 2016;62:617-22.
- Gu J, Noe A, Chandra P, et al. Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi). J Clin Pharmacol 2010;50:401-14.
- Packer M, McMurray JJ, Desai AS, et al. Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation 2015;131:54-61.
- Vorderwinkler KP, Artner-Dworzak E, Jakob G, et al. Release of cyclic guanosine monophosphate evaluated as a diagnostic tool in cardiac diseases. Clin Chem 1991;37:186-90.
- Zile MR, Claggett BL, Prescott MF, et al. Prognostic Implications of Changes in N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Heart Failure. J Am Coll Cardiol 2016;68:2425-36.
- Solomon SD, Zile M, Pieske B, et al. The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial. Lancet 2012;380:1387-95.
- Schou M, Gustafsson F, Nielsen PH, Madsen LH, Kjaer A, Hildebrandt PR. Unexplained week-to-week variation in BNP and NT-proBNP is low in chronic heart failure patients during steady state. Eur J Heart Fail 2007;9:68-74.
- Fokkema MR, Herrmann Z, Muskiet FAJ, Moecks J. Reference change values for brain natriuretic peptide revisited. Clin Chem 2006;52:1602-3.
- Thygesen K, Mair J, Mueller C, et al. Recommendations for the use of natriuretic peptides in acute cardiac care: a position statement from the Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care. Eur Heart J 2012;16:2001-6.
- Roberts E, Ludman AJ, Dworzynski K, et al. The diagnostic accuracy of the natriuretic peptides in heart failure: systematic review and diagnostic meta-analysis in the acute setting. BMJ 2015;350:h910.
Keywords: Adrenomedullin, Aldosterone, Angiotensin II, Atrial Natriuretic Factor, Acute Coronary Syndrome, Blood Pressure, Calcitonin, Calcitonin Gene-Related Peptide, Cysteine, Enalapril, Endothelial Cells, Endothelin-1, Furin, Galium, Guanosine Monophosphate, Heart Failure, Systolic, Immunoassay, Insulin, Insulysin, Natriuretic Peptide, Brain, Natriuretic Peptide, C-Type, Natriuretic Peptides, Neprilysin, Peptide Fragments, Phenylalanine, Prodrugs, Proprotein Convertases, Protein Sorting Signals, Proteomics, Receptors, Angiotensin, Renin, Substance P, Transcription, Genetic, Vasodilation
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It is called "CRIMINAL LAW" for the efforts to discriminate against the dynamic phantom with the static written rules and to distinguish the right from the wrong, the good from the bad, the innocent from the innocent.
Of course, this is our definition based on our experience.
Life, like people, is in a continuous process of change and development. As people evolve and change, life also paralles and changes with the character of the people, which it shelters and hosts.
Every development and change will result in new situations and consequences.
Criminal Law is a branch that takes precautions for events likely to happen and putting the distinction between what is necessary and what should be the norm.
The difference between what is and what should be is that it creates many subjective position such as incitement, prejudice and taxis and the subjective position such as complainant, suspect, defendant, detainee, convicted, involved, witness, witness.
Trying to manage dynamic life with static rules results in a lot of problems in practical applications.
Moreover, since it is difficult and tedious to obtain the law, laws are enacted by taking into account the provisions which are more extensively envisaged by the legislator and were only satisfied with this state for a long time.
However, the judge must be bound only by the framework of the rules in the concrete case. The details need to be walking fairly by interpreting according the dynamism of life.
However, ever changing technology and commercial life and accompanying innovations create many positive and negative effects on the individual. The question of under what circumstances the perpetrator commits the crime becomes as important as the question who had committed the crime.
The foremost task of us lawyers is to manage the process effectively and adequately as the attorney of complainant or suspect
We have to adopted a defense strategy that takes into account what the other party percieves of our strategy rather than what we are talking about our strategy.
It is also important to remember that the prevention of crime requires less labor and is less expensive than advocating crime.
Applying purely written norms without considering human psychology and sociological developments is only a PUNISHMENT without construction.
If the term LAW comes next to the the PENALTY CLAUSE, it is obligatory that all variables mentioned above should be included in the account.
Here, with the resoluteness and determination of being a party to these judgments, we, like every jurist, represent our clients in the following areas and provide consultancy services.
© 2016 UP LAW & CONSULTANCY, by Mikrop


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This trailer was released late on Friday and I thought I would hold it until today so that we can all sit and gloat together over the hiding we gave the Australians on the weekend and then watch this awesome trailer.
So… yeah lets just watch the trailer shall we?
It's only a few short weeks now until we can virtually take control of the Springboks and put in some performances that don't leave the country scratching their head and reaching for another Klippies and Coke.
Last Updated: July 25, 2011


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Being a first-time buyer is an exciting experience, albeit a slightly daunting one. If you have a history of bad credit, the process of getting approved for a mortgage can seem tough, but it certainly isn't impossible – especially with our help.
With our expertise and specialist knowledge of the market, we can find the right lender for you. While your options may be slightly more limited with a poor credit rating, we'll work hard to find a mortgage that fits your circumstances, so that before you know it you'll be able to call yourself a homeowner.
We can help you if you have experienced any of the following:


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Top 5 Staycation Ideas in Summerlin
A staycation, also called a "holistay," is a vacation you don't need to travel for. It's a great way to enjoy some time off while avoiding the cost of airfare and helping the environment by reducing emissions. Even when you stay near Summerlin, you can find plenty of fun activities to enjoy. Here are some of the top staycation ideas for the area.
Red Rock Canyon National Conservation Area
The Red Rock Canyon National Conservation Area is only about 10 minutes away from Summerlin, and it's famous for biking, horseback riding, hiking, camping, and more. It's part of the Mojave Desert, and it covers 195,819 acres. It has impressive, 3,000-foot red, tan, and orange sandstone rock formations. Scientists believe these unique rock formations are around 185 million years old. The highest peak is more than 8,000 feet tall. This place is ideal for climbing, taking beautiful photos, or just enjoying the stunning scenery.
Off-road driving is allowed on some trails, and you can see seasonal waterfalls and Native American petroglyphs. The southern end of the park includes several historic buildings. Dinosaur and prehistoric animal footprints have been found in the Red Rock Canyon National Conservation Area in three different spots.
At the visitors' center, you can learn more about the animals and plants in the region. For example, you could see bobcats, wild horses, mountain lions, red-tailed hawks, coyotes, rabbits, and many other wild animals. You can also visit the Elements Gift Shop for a fun souvenir to remember your visit. They're both open from 8 a.m. to 4:30 p.m.
The Red Rock Canyon Loop is a famous scenic drive that's 13 miles long. The loop starts near the visitors' center, and it ends up passing High Point Overlook and Pine Creek Canyon Overlook. The canyon has steep cliffs, and the views are beautiful. Experts believe the area looks the same way that it did during the Ice Age. This drive is open from 6 a.m. to 5 p.m. November through February. It closes at 7 p.m. in March and October, and it closes at 8 p.m. from April through September.
Paris Las Vegas
At the Paris Las Vegas Hotel and Casino, you can experience Paris without lengthy travel. It has a 46-story version of the Eiffel Tower with a viewing deck at the top. You can see an impressive light show every half-hour from sunset to midnight. The casino is designed to remind visitors of the streets of Paris, and you can play roulette, craps, poker, and other table games. You can also choose from more than 1,700 slot machines, and award-winning gourmet dishes are available at Gordon Ramsey Steak.
The Voie Spa & Salon covers more than 25,000 square feet, and you can enjoy a variety of French-inspired facials, massages, and other relaxing services. You can also visit the Chateau rooftop nightclub, Le Cabaret French-inspired lounge, or Le Central, a sophisticated bar with beautiful chandeliers. Napoleon's Lounge is a classic piano bar. If you feel like spending the night, you can enjoy room service and a lavish suite.
Lake Mead National Recreation Area
If you feel like a day at the beach, visit Lake Mead National Recreation Area. It's about half an hour away from Summerlin. Lake Mead National Recreation Area was the first national recreation area in the United States, and it's still the largest at more than 1.5 million acres. You can go swimming, boating, hiking, biking, camping, water skiing, and fishing. The lake has rocky cliffs, sandy beaches, and several coves and small islands.
Boat and personal watercraft rentals are available at Callville Bay, and you can have lunch at the Callville Bay Lounge. Lake Mead has more than 750 miles of shoreline, so there are plenty of places to explore, or you can also relax on the beach. The area includes Lake Mojave as well as Lake Mead. You can also check out the Hoover Dam and a variety of canyons, valleys, and mountains. The Lake Mead National Recreation Area visitors' center and gift shop are open from 9 a.m. to 4:30 p.m.
Shark Reef Aquarium
The Shark Reef Aquarium is at Mandalay Bay Hotel and Casino, and it's the only predator-based aquarium in North America. More than 2,000 animals, including sawfish, giant stingrays, rare golden crocodiles, jellyfish, piranhas, and endangered green sea turtles. Two underwater tunnels make you feel like you're diving alongside the ocean predators, and you can see 15 different species of sharks. There is a sea life petting station and a VR theater where you can experience swimming with a pod of humpback whales. It's open from 10 a.m. to 6 p.m.
New York New York Hotel and Casino
The New York New York Hotel and Casino can bring the Big Apple to you. It has a replica of the Manhattan skyline, including scale models of the Statue of Liberty, the Brooklyn Bridge, and the Empire State Building. The Big Apple Coaster is in the middle, and it can travel at up to 67 mph. While you're at the top, you can catch an excellent view of the Strip. It's open from 1 to 9 p.m. Monday through Thursday and from 11 a.m. to midnight Friday through Sunday.
There's also a New York-style pizzeria and several bars and shops. Hershey's Chocolate World offers more than 800 types of Hershey's candies and chocolates, and the Big apple Arcade has some of the latest video games. You can try classics like air hockey and Skee-Ball as well. The Nine Fine Irishmen pub was built in Ireland and shipped to Las Vegas, and Beerhaus has craft beers and great snacks. You can try the New Yorker classic facial or the City Lights masque and massage with papaya and pumpkin at the luxurious spa.
These places are ideal for a fun, relaxing staycation. You can stay in your own home or relax in a hotel. What are your favorite staycation places? Contact us and let us know if we missed any of the attractions you like visiting most.


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PROPERTY DESCRIPTION Test
This charming single-level courtyard Spanish sits on a wide tree-lined street in Northwest Glendale near to Kenneth Village and has been tastefully updated while preserving much of the home's original character such as archways, vintage hardware and more. The Living Room with period fireplace and bay window and the Dining Room with original wood windows overlook the courtyard entry. The updated eat-in Kitchen has granite counter tops, stainless appliances, a separate prep sink, recessed lighting and opens to the Backyard through the service porch. The three Bedrooms are bright and cheerful and feature charming plaster relief details. Both the full and half Bathrooms have also been upgraded tastefully. The Backyard features a large covered patio, lots of grass and many fruit trees including satsuma mandarin, cara cara and valencia orange, persian and mexican lime, rio red grapefruit, haas avacado, pineapple guava, fig, and boysenberry bush. The Garage has been finished to incl storage, a work bench, a tool shed and durable epoxy flooring. Disney/Dreamworks close.
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Cheap Flights to Stuttgart
Looking for a cheap flight to Stuttgart? We are not surprised that you want to visit Germany!
To find the best flight connection we recommend you to use Beoo.com, the best multi-purpose holiday search engine! By using our website you can be sure that your dream deal will come true. Beoo.com finds out most of the popular travel sites and allows you to check all the prices as they are. You have to search smarter to get the cheapest flight.
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Next-generation STEM leaders celebrated during SouthCoast Community Foundation award reception.
NEW BEDFORD, MA – The SouthCoast Community Foundation hosted its 21st Annual Jacobs Family New Bedford High Schools Scholarships reception virtually on Friday, May 13th, where five New Bedford students received awards totaling $175,000. Zachary Bois, Raven DeGrace, Samuel Thomas Jupin, Sabrina Rosa Costa, and Katherine Maldonado Montoya each received a four-year $35,000 grant from the SouthCoast Community Foundation to support their STEM-focused academic pursuits. Joining the Community Foundation, school leadership, previous Jacobs scholars, were donors Dr. Irwin and Joan Jacobs and Mayor Jon Mitchell.
"With these five new scholars, there are now 93 New Bedford students who are benefitting from the Jacobs' kind spirit, generosity, and encouragement to use their college education and future careers to make the world a better place, to safeguard our democracy and planet," stated SouthCoast Community President and CEO, Leonard M. Lee. "We are honored to steward this fund on behalf of Irwin and Joan Jacobs and help Zachary, Raven, Samuel, Sabrina, and Katherine pursue their educational dreams and aspirations."
Grant Recipient
High School
Zachary Bois
New Bedford High School
Raven DeGrace
New Bedford High School
Samuel Thomas Jupin
New Bedford High School
Sabrina Rosa Costa
Global Learning Charter Public School
Katherine Maldonado Montoya
Greater New Bedford Regional Vocational Technical High School
The Fund annually provides five four-year scholarships, up to $35,000, to one New Bedford Global Learning Charter School, three New Bedford High School, and one Greater New Bedford Regional Vocational Technical High School graduating seniors who major in a STEM (science, technology, engineering, math) related field. In the fall, Zachary will pursue a degree in Forensic Accounting at Franklin Pierce University. Raven will attend Gordon University, where she will major in Psychology with a concentration in Counseling. Samuel will be studying Zoology at the University of New Hampshire. Sabrina plans to study Psychology and Psychiatry at the University of Massachusetts Dartmouth, and Katherine also plans to attend the University of Massachusetts Dartmouth to study Computer Science.
Addressing the scholars and attendees, Mayor Jon Mitchell commented, "The Jacobs Scholarship event has become a rite of spring. The awards are a recognition of excellence and an acknowledgment of hard work. The Jacobs have been there for New Bedford and our students time and again. We are profoundly grateful to them and the Community Foundation, teachers, and administrators for their support. Congratulations to the recipients. We will be watching you move along in your academic and professional careers and hope you will come back to New Bedford to share your talents, just like Dr. Irwin and Joan Jacobs do every year."
The Jacobs Scholarship was established in 2000 by New Bedford native Dr. Irwin Jacobs (New Bedford High graduate, Class of 1950) and his wife, Joan, to honor two New Bedford High School educators who made a huge impact on Dr. Jacobs and his future career, Philip Bronspiegel and Melver C. Felton, Jr.
Dr. Irwin Jacobs remarked, "A big congratulations to the 2022 awardees. It is always exciting to meet the new scholars and reconnect with our past recipients every year. While pursuing our education, Joan and I benefited greatly from scholarships. Without that support, we wouldn't be in a position today to help others. It gives us great pleasure to do so and cheer them on as they progress through their academic and career paths."
The SouthCoast Community Foundation is a nonprofit serving the communities of Southeastern Massachusetts through philanthropy. The Community Foundation mission is to mobilize philanthropy by matching donors and resources with community needs for the benefit of our region. Since 1995, the organization has distributed over $50 million from more than 200 funds to humanitarian, educational, and cultural organizations in the region. For more information, visit www.southcoastcf.org.
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Top to bottom: New Bedford High School Students Zachary Bois, Raven DeGrace, Samuel Thomas Jupin; Global Learning Charter Public School student Sabrina Rosa Costa; Greater New Bedford Regional Vocational Technical High School student Katherine Maldonado Montoya


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Currently unavailable until further notice.Immerse yourself in local island culture by visiting a Hawaiian luau. Located in Waikoloa on the Big Island's Kohala Coast, Ho'omau Luau invites you to experience traditional island dishes and live entertainment. The luau feast features a wide variety of delicacies prepared fresh by Mai Grille Restaurant, which was elected as Best Chef in 2018 by Best Chefs America.
Besides great food, Ho'omau Luau features performers who will take you on a journey through Polynesia, stopping at exciting locations like Tahiti, Samoa and New Zealand. Enjoy an evening of local island culture and great entertainment!
Luau Highlights:
Luau Inclusions:
Dinner Menu:
Please note: Menu is subject to change.


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Stability and tension
Penziner, Richard Lyle
MetadataShow full item record
Sculpture enables me to translate thoughts and feelings Into tangible form. The pieces Included In this exhibition demonstrate two distinct, yet closely related, types of structural forms: the tenuous and the stable. Both of these forms have been used to activate or animate my sculptures. The tenuous pieces possess an excited state with the potential of energy release. The focal point of these structures Is the element within the piece that creates the force or resistance against the material. I relate to this aspect of my sculptures on a sensual level where the process of building and conceiving the idea Is experienced through manipulation and construction of the material. This Is an embodiment of my physical energy and Is reflected through their tense gestures. In the stable structural forms the material Is not stressed; rather, the focal point is the idea of support, emphasizing the element which rests on top. These pieces represent stability and permanence and are the antithesis of tenuousness. I relate to them as the structures that support my intellectual and rational energies. Together the sculptures achieve a balance of separate aspects of my working process. For me sculpture Is most successful when it achieves that balance within itself.


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The latest news on birds from Australia is that the ivory billed woodpecker and 22 other bird species have all been confirmed or considered as extinct.
This is really bad news for the millions of birds who use the forest of Australia for shelter, food, and nesting. A recent study by the CSU-La Australia stated in a release; "We call this the largest bird drop in history, more than three times worse than the birthing of the dinosaurs some 65 million years ago." These birds were a part of a massive avian decline that occurred when the dinosaurs became extinct.
With so many species are going extinct, it is important to make sure we do everything we can to save these little guys before they go. It is amazing that so many people have a misconception of what is causing the extinction crisis. Some people believe it is global warming, when in fact it is a combination of factors. Here are some of the latest news on birds of prey that has caused the extinction of an estimated 22 species:
– The Australian Woodpecker: This medium sized woodpecker was the most recent addition to Australia's threatened species list. They are nocturnal hunters and primarily feed on the ground. They have also been recorded at taking down large birds, such as wombats and emus. They also have a strong predatory instinct, especially of small animals. The latest signs suggest that their population is slowing due to a lack of females.
– The Bled Pinky: The beautiful little songbird known as the bled pinky was the last known species to be seen by scientists with the exception of two species. These two birds were brought from Europe and are now extinct. Their loss is due to a massive outbreak of something called feather washing. It is believed that this disease will wipe out one of every seven bird species in the area over the next decade. It is a disease which kills off both mature and eggs alike.
– The Ivory Billed Woodpecker: The ivory billed woodpecker was the second bird to become extinct on Australian soil. They were first documented about thirty years ago in the coastal city of Armidale. Unfortunately for the species, they were soon trapped and later killed for the meat. Their leather is highly sought after in countries like Vietnam and Thailand. Their carcass is often found with many prized trophies. Unfortunately for the world, these birds were never able to reproduce.
– The ivory billed woodpecker and its close relative, the black-necked woodpecker, share many of the same threats in the region. The two birds have very similar diets, feeding on small seeds and worms. They both also eat vegetation and bark, including infested trees and the evergreen shrub Black Eyed Susans. Unlike other types of woodpeckers, the ivory billed woodpecker will not spray its feathers or droppings. This trait makes them more difficult to detect.
– The Golden Woodpecker: The golden woodpecker was also believed to be extinct over twenty years ago. However, in 1993, the bird was seen by experts on a bird tour in Malaysia. The experts soon realized that the bird was a member of a rare species called the Caracal Keratinook. This species is only found in the rainforests of Brazil and Peru.
These birds have all suffered from the same fate: loss of habitat and prey. Many species of these woodpeckers have already become extinct. But, the future for this species looks bright since it is still present in the Amazons of the Amazon River Basin. In fact, it is said to be one of the most vocal birds in the jungle. Its song has been known to create a gale-force wind in the area.
Provided by Antonio Westley
Disclaimer: This article is meant to be seen as an overview of this subject and not a reflection of viewpoints or opinions as nothing is definitive. So, make sure to do your research and feel free to use this information at your own discretion.