text:
Sunday, December 31, 2006
What a Difference a Year Makes...
Friday, December 22, 2006
Subscriber Spotlight: Just Jack 2006
- Swooning over guys with strong arms
- Bringing two kids each into this world to add to the Army we're forming
- L-O-V-I-N-G the movie Chasing Amy
- Holding a place near and dear to our hearts for classic Salsa music
- Loathing people who make IM spelling errors...YOUR is not the same as YOU'RE, dammit!!!
File Under: T...M...I
And I really don't have any more apologies left in me, so I felt it was just easier to post something tonight and get it over with.
Why Me?
A couple of weeks ago I read about some kid who got stabbed to death in broad daylight in Union Square while people where there in full swing doing some holiday shopping in the open market. Just this big-ass'd brawl of HS kids trying to kill each other. Sad but true. I've since found out that it might be gang related. One of the gangs involved? DDP, or as they are really called, but I'm embarrassed to admit, Dominicans Don't Play. I mean is that just the stupidest name on gods green earth that a gang could possibly have? This city if full of Decepticons, Bloods, Crypts, Latin Kings...and Dominicans who don't play...
And what, pray tell, do they not play? Jump rope? Backgammon? Red Light, Green Light? I mean, I'm not doubting that they are as ruthless and bad ass as any other knife/gun wielding gang in this city. But that name...it's really just poor marketing. They need a PR rep really bad! I'm just a tad embarrassed because, well, they're Dominican. And I for one do not see what's so bad about playing. I mean, do you feel me?
If It Wasn't for Step 3...
I've really been toying with the idea of sitting in on a couple of the Sexaholics Anonymous meetings to see if it's the missing "piece" in my quest for "peace" but dammit if they didn't throw that god clause in there. Can't I fix this without bringing anymore Judeo-Christian oppressiveness into my life? That's the main cause behind all this in the first place, all that repression I was taught in the church; the shame that it preaches and embeds in your mind- that shit really fucks with a kid's head...no pun intended. Can't I just go to a meeting and accept responsibility for my actions without putting it in some supposed celestial being's hands? That's such a passive way to go through life: it's in god's hands. No it's not- it's in my hands. I can do this; I have to do this; it's my responsibility to bring about change in my life.
Hmmm...maybe I don't need those meetings after all...
MEMO TO SELF: Rent The Brown Bunny RIGHT THIS MINUTE!!
So, um, Vincent Gallo, wannabe musician, D-list indie actor and all around weirdo, who amused me in Palookaville and wowed me in Buffalo '66 and In The House of the Spirits, is upset with PayPal.com because they refuse to do business with him anymore for his website, http://www.vincentgallo.com/. Vincent, sweetie, I'm mad at you for selling a night of sex with you as well as YOUR SPERM on your website. And I'm mad that VG can sell his body online no problem, but if I do it it's prostitution. Is it because he's a man or an actor? To me, soliciting is soliciting. Why isn't LAPD doing their job? Get this nutcase off the streets before he (re)produces again!
No, It's Not Okay to Talk About This with Me
It's bad enough that I've allowed myself to embark on this faux-friendship, in which I pretend that this torch I carry for you is just the latest fashion accessory, and you pretend that the reasons you gave for our demise weren't ambiguous at best, but do I really have to sit on the other end of the phone at two in the morning while you seek my advice on your girl troubles? I still haven't seen a doctor about this knife in my heart, so let's lay off the dating details until my wound heals, k? Say it with me, now: T...M...I...
Some Stereotypes are Just True
Did you know, that in the Christian Bible, the inhabitants of Sodom and Gomorrah were considered sinners by god because of their perverse sexual acts (fellatio, anal sex, man on man action), but in the Jewish accounts of this biblical event, Sodomites were guilty of economic crimes and monetary greediness. People, I cannot make this stuff up. Draw your own conclusions...
*smooches...with new-found respect for racist jokes*
We fall down
But we get up...
For a saint is just
a sinner who fell down...
and got up
Saturday, December 16, 2006
You Call That News?
I really hope there aren't any surveillance cameras in my office because they totally have me on tape rolling my eyes at the computer and laughing out loud at the ridiculousness that the NY papers deem "fit to print."
In Other News, Bush and Osama Say to the World: Smile! You're on Candid Camera!!
Why would anyone be so crazy as to believe that any real strife would befall Belgium? Besides of course their stash of waffles and chocolate falling low. Now there's your story!
But I hear he used his legs to shove Timmy down a well...
Hey, you, tall Doofus, come over hear and yank some plastic shit out of these here dolphins we're holding in some tanks against their will. And while you're at it reach up, grab the sun and tilt it about 2 degrees for me, will ya? I mean geez- it's bad enough he's a doofus, you gotta exploit him, too?
Oh my god...I'm go-go, too!
Dude, you shake your ass so other dudes can jack off to it. I hate to be the bearer of bad news...but that IS porno! Let's call a spade a spade, okay?
Has anybody questioned Elmer Fudd?
That damned rabbit must be putting up "duck Season" signs again...when will those two just call a truce?
Because worrying about his health would probably not be politically correct...
Another reason why I try to stay as uninvolved in politics as possible: I don't want any slime to get on on my leather jacket...
And this is why I got rid of my machete.
I mean really, if you're going to treat your kids like shit, don't make it easy for them to kill you. It's covered in chapter 2 in the new millenium parenting guide...didn't he get the 2006 edition?
He's probably at Osama's house.
Don't even waste my tax dollars looking for this fool. I don't want to hear another word about it.
Sometimes you just need to beat the hell out of a kid...
Oh. Did I just say that out loud? I certainly do not condone child abuse, nor do I promote threatening to put your 6-year-old in the oven and serving her for dinner with a spicy mango chutney...
That's all I got. If I read anymore news the weight of the world will crush my spine.
*smooches...with a side of spicy mango chutney*
Well, if you told me you were drowning
I would not lend a hand
I've seen your face before my friend
But I don't know if you know who I am
Well, I was there and I saw what you did
I saw it with my own two eyes
So you can wipe off the grin, I know where you've been
Its all been a pack of lies
Friday, December 15, 2006
Redemption Song
Now this is where I usually insert something callous and witty like: "get over it" or "hmmm…where's my violin?" and that will usually incite rumbling laughter from you, my loyal readers. But apparently that is just the type of "wit" that has brought me to this post.
Yes, I, Raquel, she of the scathing tongue, want to apologize to all injured parties of previous posts that at the time seemed really funny but was actually really hurtful. And I'm not using my sarcastic voice either. I'm actually taking off my armor, putting down my shield and admitting that I use this mean-spirited humor in a desperate attempt to protect myself from myself, the typical bully mentality. It's the one thing I remembered from Psych 101…you know, from the one day I actually attended class?
I want to reiterate to that injured party that what I wrote was just words on a screen. That despite what those words connotated and despite how they were interpreted, my feelings for this injured party remain as they always were. And if said party is not sure of those feelings because my armor and shield have gotten in the way, let me tell them here: there is not a day that goes by that I don't miss you deeply and wholeheartedly. And not a moment passes without a memory of our time together popping in my head and making me smile. Please know this to be the truth.
And while I'm at it, let me address other wrongs. Might as well get it all out before I suit up again.
JS: I don't know why I never called you back. We had an awesome time that night and I thought you were a cool person. Sometimes when the weekend approaches I contemplate calling you but figure you have already written me off as a flake and deleted my number from your phone. I'm really not this dismissive of people, really. I got caught up in my own stuff and I apologize. It'd be nice to hang out again if you still want to.
Jack: I'm really happy you've found something to be happy about. I really am. Please don't think that my self-imposed seclusion has anything to do with you. It has everything to do with me. But you have an IQ of 144, right, so I suppose you already knew that.
C, Hoover and Toothless: If you ever come across this blog, I want to say that what I wrote I meant, but I didn't have to put it out there for the whole world (actually only 17 people) to laugh at. I'm sorry.
L: If you ever come across this blog and come to find that there are things I kept from you, I'm sorry, too. Just know that were are really good friends, and if I didn't divulge something it was only because I was ashamed to admit it to you, because I really admire you and your morals and your friendship, and I wanted to keep your image of me pristine.
And finally, in a last-ditch attempt to keep bad Karma from re-visiting me, I want to apologize to Mrs. McDonald and her baby. I knew it was wrong when I did it the first time. And I knew it was wrong the second time, too. I promise you- there won't be a third.
*smooches…with so much love for you all that my cup runneth over…*
Siempre me quedara
la voz suave del mar,
volver a respirar la lluvia que caera
sobre este cuerpo y mojara
la flor que crece en mi,
y volver a reir
y cada dia un instante volver a pensar en ti.
Tuesday, December 12, 2006
It's Still Not Easy, But I'll Get There, Kermit...
I have not been able to write in weeks. None of my stories for my thesis have an ending and it's just not coming to me. The 25-pg "craft" paper is holding steady at 12-pgs with not a single, new original thought popping into my head. That damn blinking cursor on my computer screen is mocking the hell out of me, and I swear, yesterday it said, "You're a fraud. You're not a writer. All of your stories are the same. All you've done is changed the protagonist's name."
Fucking, stupid, bitch-ass voices!
It's made me a bit self-destructive and careless and I really thought I'd left all that behavior behind, but no, it's been there the whole time just waiting to be reactivated. My insomnia is getting worse. I'm getting sloppy at work. I've gained five pounds. I'm so mentally exhausted that it's causing a disconnect inside of me. I just need to shut down and re-boot, so to speak.
So that's what I'm going to do.
This is driving me nuts because I've never really had writer's block before and I'm scared that I won't get my flow back. I feel like a singer who has lost her voice and I'm freaking out. Is there some sort of lemon tea thing I can take to revitalize me?
And I swear to god if someone says "therapist" or any variation thereof I will snap you in two! Literally. There will be two bloody pieces of you lying about. Don't test me.
Now some of you will think this is a cry for help, but the rest of ya'll know me better than that. I say what I mean, and I mean what I say. I'm not looking for sympathy or an outpouring of love. I really truely just need a couple of days to regroup and get back on track. I just didn't want anyone to think I was ignoring them.
But I'll give you this, a present, a relic from my childhood that sort of calms my soul. Hushes the voices, if you will. No matter how low or crappy. This is my self-esteem secret weapon. You should feel honored to know it:
*smooches...from me for me for once*
I've took it farther on the outside
I've took it nearly to the brink
And if you've seen me on the outside
You would have barely seen me breathe
Saturday, December 09, 2006
Hip Hop Hooray...Ho...Hey...Ho...
I'm officially legally unbound to that man! It took exactly one year, one month and 28 days from the moment his sorry ass left my momma's house to this moment, and I have to say I'm a little overwhelmed.
First I'd like to thank L in Cali for all of her support, perspective, advice and comic relief throughout this whole ordeal, even though she doesn't read this blog (I'll be thanking her in person later on this month!).
I'd also like to thank my family who didn't choose sides or say, "I told you so," but instead were there as a constant source of support.
And to C's and my mutual friends (is that gramatically correct?) and fellow AU alumni who may have been a little thrown by the split- you guys are amazing and I ♥ U!
Finally, I'd like to thank the Academy...you like me, you really, really like me...no seriously, though I want to thank the Queens County court system, Michael Ciarlo and Kenny the Paralegal at Nadel & Associates who really helped me out a lot with all the gory details of this divorce. You guys ROCK!
Now that it's over, I suppose I can reflect on the 13 years he and I spent together- both the good and the bad and the ultra- mega- funky- awfulness that brought us here. I've made our time together seem like a ride through hell on an oil soaked rickshaw, but of course there are two sides to every story.
I'm sure he would say I was difficult, bratty, moody and unpredictable, and that I had this standard of perfection that no one on earth could possibly live up to...but you all knew that about me already. And I'm sure you're all tired of hearing me say how boring, financially irresponsible, and unhealthy he was, and how irritating he became in those last few months. There were other, more serious underlying problems, too, that I won't go into out of respect for his privacy (look at me, all grow'd up!), but if you ask me I'll tell you one on one.
There were many times I tried to leave, he tried to leave, I tried to kill him (lucky for him he had really good reflexes and caught my wrist in time or that knife would have seriously still be stuck in his throat!)...the usual ups and downs, but it was magnified by the 10th power in my mind and I've known for a while that it had to end.
So here's to love, marriage, babies and divorce- not necessarily in that order. And here's to my new life: May the road rise up to meet me...May the wind always be at my back...May the sun shine warm upon my face, and rains fall soft upon my fields...
*smooches...on my way to pawn my wedding ring*
i thought we'd be simple together
i thought we'd be happy together
thought we'd be limitless together
i thought we'd be precious together
but i was sadly mistaken
Thursday, December 07, 2006
I'm Being Forced to Read the Paper
Yeah, that's what I said, too.
There is so much information crammed into my poor, beer-soaked brain right now that I think it might implode. Some dude gets shot outside a strip joint by the cops; a boy gets jumped in Union Square; Lindsay Lohan sends some crazy email to her lawyer that is leaked to Page Six...I just can't keep up! The only way to get these stories out of my head is to do the same thing I do when a song just won't leave me alone: write it down.
Here's the recent news, according to me, the Jaded NYer...
1. 50 Bullets
I agree that was excessive, but here's my problem with this story: a) why were they taking the stripper home? b) why did Bell ram his car into the cops? c) why do cops carry around THAT MUCH ammo d) why do black people keep inviting Al Sharpton into their lives? I can't STAND him!
Listen, plain and simple, if dude hadn't been so preoccupied with getting some skanky stripper ass the night before his wedding to his baby momma, his ass would still be alive today.
2. Pelosi and Murtha
I don't usually follow politics, but a couple of weeks ago the NY Times had this cover story on Nancy Pelosi endorsing John P. Murtha as the next House majority leader, and how no one else backed it and they chose some other dude instead. With the article was this pic:
That's Murtha, in the back, to the right, with the STANKEST look on his face, while Pelosi and the REAL House majority leader ham it up for the press. That made me laugh so hard I almost peed my pants!
3. You Mean I Gotta Be Sober on My Commute?
Ha Ha Ha Ha Ha!!!
Commuters on the LIRR are complaining because the bar-car may be abolished. Listen you alcoholics, stop being whiny-assed babies and just have a beer at Charlie O's at Penn Station before you get on the train instead, okay? Geez- it's not the end of the freakin' world. Give your liver a BREAK!
4. News from the Dominican Republic:
A) No More Haitians?
Foreign Relations Minister Carlos Morales Troncoso, a former sugar cane industry executive, highlighted the fact that the trend is for increased investments in farming mechanization that will eliminate the need for Haitian labor in sugar cane fields. Dominicans reject the hard work of sugar cane cutting, which has led to thousands of Haitians being allowed to migrate to the country to take their place. These Haitians live in settlements called bateyes, many languishing today as the number of jobs declines because farms are being mechanized.
But, who will be our scapegoats if the Haitians stop crossing the border to do the work uppidy Dominicans don't want to do? Who?? WHO???
In a press release, the Cerveceria Nacional Dominicana (that produces Presidente beer) says that beer drinkers will be most affected by the fiscal reform, estimating that they will pay more than 36% of RD$ 17.5 billion the government is trying to collect. Currently there is a tax on beer depending on the percentage of alcohol, but the fiscal reform looks to impose a selective tax on beer. Teodoro Hidalgo, Director of Corporate Affairs for Grupo Leon Jimenes, says that this tax increase means that beer in the DR will become one of the most expensive in the hemisphere.
First they take our Haitians, now they want to make it harder to buy beer...why even bother living?
5. Hey, This OrthoTriCyclen Tastes Like Hubba Bubba...
Are they kidding me with this one? Chewable Contraceptive? I can see it now: "Jenny can you please spit out your gum? You know it's not allowed in class" "But Mrs. Funkenmeyer, it's my birth control gum!" Now I guess you can be a whore and chew gum like one, too! Whatever happened to the Rhythm Method, huh? Actually, maybe you shouldn't take birth control advice from me...
Okay, that's enough with the news. My head hurts and I need a shower to take the stench of society off of me.
*smooches...with icky newspaper ink all over the place...*
No creo en Venus ni Marte
No creo en Carlos Marx
No creo en Jean Paul Sartre
No creo en Brian Weiss
Solo creo en tu sonrisa azul
En tu mirada de cristal
En los besos que me das
Monday, December 04, 2006
Oh This Is Gonna Be Fun!!
Saturday, December 02, 2006
French Fries: The New Heroin
These are the days that I've been missing


text:
"It was always you" is now available at Amazon Kindle in e-book format. This is the first story in the series – Inspired by the Song. The inspiration came from the song by Maroon 5 in 2014.
At 99 cents or pence its a short story that will grab your attention.

subset: commoncrawl


text:
Croquet in the North West
North West Federation of Croquet Clubs - for everything Croquet in the north west
31 August 2012 by Tony Thomas Leave a Comment
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text:
12 July 2014 10:32AM • 0 comments
LONDON - Lionel Messi is struggling at the World Cup because he is suffering from exhaustion, his father Jorge has claimed ahead of Argentina's final showdown against Germany tomorrow.
The Argentina playmaker, who was being hailed as potentially the star player of the tournament, has faded to become a peripheral figure in his past two games.
The Barcelona star neither scored nor provided an assist in the 1-0 quarter-final victory over Belgium or the semi-final win on penalties against Holland.
He did provide two match-winning moments in the two games prior to the Belgium clash, the group-stage victory over Switzerland and the round-of-16 clash with Algeria but on each occasion his vital contribution came in the final minute.
He has been heavily man-marked throughout the tournament, partly explaining his cameo performances in the tournament's latter stages.
And the burden of expectation appears to be taking its toll on the Argentine talisman. After speaking to his son recently, Messi's father Jorge told Brazilian newspaper Folha de S.Paulo that he is suffering from extreme fatigue.
"Leo (Messi) said it looked like his legs weighed 100 kilos. He was very tired," he said.
Meanwhile, Germany say they have formulated a plan to stop Messi, but assistant coach Hansi Flick insisted: "We're not going to reveal it."
Benedikt Höwedes, the Germany left-back, said that Messi must be collectively neutralised and knows that the 7-1 win against Brazil will be rendered meaningless should they lose.
"Messi is a fantastic player, one of the best in the world, but so was [Cristiano] Ronaldo," he said. "You can't play alone against him. We've got to work as a collective against him because we're not going to be able to beat him one-on-one. If we can defend decently as a team we'll contain him.
"Many people are giving us slaps on the back but we can't make the mistake that it's already over, far off it. People are saying in Germany that the title is almost in our pocket but the Argentines will fight to take the title home. If we don't win, the semi-final will just be consigned to the archives of history."
The striker dedicated Wednesday's victory over the Netherlands to Argentine journalist Jorge Luis Lopez who died earlier in the day after his taxi was hit by a stolen car in central Sao Paulo.
"Big hug to all of Argentina and a very special keepsake for Jorge 'Top' Lopez. This victory is especially for you, buddy. A big hug to the family. Courage," wrote Messi on social media. – Agencies
Brazil v Holland 9pm
Germany v Argentina 9pm
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text:
Monday, April 25, 2011
The bounty was huge.
All of us bunnies are recovering.
Hope you all had a wonderful weekend!
14 comments:
- Pomona said...
At least the bunnies' heads don't get bitten off first at your house - it shows sensitivity!
Pomona x
- April 25, 2011 at 11:31 AM
- Debbie @ Swampbilly Ranch said...
It looks like quite a party. Glad to see you are recovering.
- April 25, 2011 at 12:34 PM
- Vintage Tea Time said...
Wow, a chocolate rave, clearly!
- April 25, 2011 at 1:03 PM
- Lindsay Jewell said...
Hehe. That's a familiar sight.
- April 25, 2011 at 1:25 PM
- andrea creates said...
i just snapped the ears off of my chocolate godiva bunny :)
- April 25, 2011 at 1:41 PM
- Bobo Bun said...
Feeling sad it's all over as it was wonderful. We're left sitting in a huge pile of foil and choccy stains. Like your plastic eggy things.
- April 25, 2011 at 3:01 PM
- greenrabbitdesigns said...
Lovely time, boy have we eaten some chocolate!!!
Vivienne x
- April 25, 2011 at 3:34 PM
- beck said...
So Much Chocolate....x
- April 25, 2011 at 3:48 PM
- m.e (Cathie) said...
ours was not so bad! lucky Pony girl hey!
they had one little bunny like that and it's still half there.
phewwww, i don't think a chocolate high is needed for my energiser bunnies.
happy week Ms LolaNova ♥
- April 25, 2011 at 4:32 PM
- the happy honeybee said...
Hah hah, looks like Easter was a triumph in your household! Love the decimated bunny photo.
- April 25, 2011 at 4:46 PM
- Tas said...
I'm not holding out much hope that the pictured bunny is going to recover!
- April 25, 2011 at 10:12 PM
- lifeshighway said...
We did and I hope you and your family did. The aftermath is epic.
- April 26, 2011 at 4:04 AM
- Sherri B. said...
Looks like The Easter Bunny left a load of goodies for Miss Pony Girl..What a sweet girl to leave the head on the bunny!
- April 26, 2011 at 8:05 AM
- Janee Lookerse said...
Oh man... I got The Beard one of those Godiva Bunnies made exclusively for Target. Wow. We ate it in one sitting. No joke. 5 servings. Yep.
- April 28, 2011 at 9:21 PM


text:
a blog of my experiences and observations of making ISK in Eve Online, from the beginning. - - - - Ingame chat channel: Ironforge Commerce Guild - - - - - - If you are a new trader and want to learn my methods, start at the first post from 14 May 2013 and read onwards . . . . . view this as an ISK Guide
- Blog
- About the blog
- Eve Business Blogs
- Useful Videos
- Eve Online Trading Podcasts
- CSM9 Blogs
- Eve Online vs World of Warcraft
- What is Eve Online?
- CCP Financials (as published)
- CCP hf. Consolidated Financial Statements for 2016
- CCP hf. Consolidated Financial Statements for 2015
- CCP hf. Consolidated Financial Statements for 2014
Saturday, 12 April 2014
Team Security - a nice ISK sink.
What interested me was how much ISK they had seized since September 2013. As shown below in their graph, they have seized 19trn ISK, with 4.2trn ISK seized in March alone!
This is perhaps a major ISK sink in the game.
Though, to put this in perspective, back in March 2013 the size of the Eve Online economy was (called Gross User Product by CCP, or the value created) was about 135trn ISK [source is the Eve Online Economy lecture at the Fanfest - youtube video starts at the correct place on this link]. Hard to know what the economy has done over the last 12 months but perhaps safe to say that in March 2014 Team Security took 4% of the economy out of action.
6 comments:
I never, ever considered the effect of this as an isk sink. That's a very interesting observation there...
Another perspective: If I am not mistaken, the daily PLEX market in Jita is about 2000 sales per day (or 1.4 trillion isk, roughly). On the "bad" months, CCP has seized 3-5 days of PLEX.
If the people who purchased isk on the black market instead purchased PLEX, CCP's finances would be improved, and supply on the market would increase, making PLEX prices a bit more reasonable.Replies
Interestingly some people don't realize they can buy from CCP because they have always gone to sellers. The stories that occasionally pop up are wild.Delete
Here's a clip from the 2012 Economy presentation where Dr. Eyjo talks about the size of the isk sinks and faucets to give some perspective on the size of the seizures. The clip should start in the right place.ReplyDelete
In the forum thread about this week's Caldari Manhunt live event, both Eterne and Falcon say that the PLEX prizes for the event come from confiscated RMTers. I thought that was fascinating, from an in-game economy standpoint as well as how it looks security and PR-wise.ReplyDelete


text:
WCOOP 2012: Panama's Puropoker123 puts away Event 46, $320 NLHE [2X Chance]
As anyone who keeps up with the wide world of land-based poker tournament tours sponsored by PokerStars can tell you, the Latin American poker market has really taken off in the last few years. That success has bled over into online tournaments, including here in WCOOP where past events have been won by players from Uruguay, Argentina, and Brazil. Today Panama joined the ranks of those nations with a WCOOP win by one of its own.
After a night's rest to recharge their poker-playing batteries, the 22 players who survived Day 1 of this $320 No-Limit Hold'em re-entry event came back to play more poker at 2 p.m. ET today. Play resumed at the beginning of Level 31(6K/12K/1.5K) with no extreme short stacks - everybody was working with at least 18 big blinds, including Puropoker123, who was in the middle of the pack with 581K in chips.
By the first break 16 players remained, led by the day's incoming chip leader, the Czech Republic's dsnka (1.77M). With nobody desperately short-stacked, there was plenty of post-flop play and a corresponding amount of movement by the players up and down the leaderboard. All that back-and-forth saw another five players leave in the second hours of play, taking the field down to just 11 at the second break. With blinds up to 15K/30K, Portugal's Poeira4 led the way with 2.56M.
Halfway into the third hour of play, this heartbreaker of a hand sent former Team Online member Andrew "foucault82" Brokos out on the final table bubble:
With just a few minutes left on the 15K/30K/3.75K level, the final table began with these nine players:
Seat 1: Puropoker123 (1,284,644 in chips)
Seat 2: Armand2011 (1,157,878 in chips)
Seat 3: jenbizzle (1,574,001 in chips)
Seat 4: Festivuss (613,234 in chips)
Seat 5: Kora Fett (1,076,616 in chips)
Seat 6: dsnka (1,724,186 in chips)
Seat 7: Poeira4 (2,602,654 in chips)
Seat 8: StigR (2,443,349 in chips)
Seat 9: samuraiUA (2,013,438 in chips)
It looked like the short-stacked Festivuss would be the first player eliminated from the final table after a preflop shove with A♥ Q♦ was met with a re-shove from dsnka with K♥ K♦. But the board came Q♥ Q♣ 8♦ 9♠ 4♣, pulling the Argentinian player back into the thick of things. As for dsnka, the dip in chips was short-lived; minutes later a double-up came with A♥ K♦ against Armand2011's A♠ Q♣ to jump back over 1.5M chips. Then, after the blinds went up to 20K/40K with a 5K ante, came a huge double through StigR to seize the chip lead.
The hand started with dsnka opening for the minimum of 80K with 1.12M chips behind and calling a three-bet to 187K from StigR in the small blind. StigR led out for 164K into the 460K pot when the flop came 8♥ Q♣ 3♠, and after a few seconds' thought dsnka shoved all-in. StigR didn't waste any time calling with A♠ A♦, which was well ahead of dsnka's 8♦ 7♦. But that all changed when the turn brought the 7♥ to give dsnka two pair. The river was the T♦ and dsnka grabbed a 2.71M-chip pot - and a slim chip lead.
The lead was short-lived, though, as Poeira4 jumped out ahead of everyone after grabbing a 2.14M-chip pot in this battle with jenbizzle:
One orbit later the ice finally broke after two of the shorter stacks at the table collided. Puropoker123 opened for the minimum in the hijack and Armand2011 moved all-in for 272K. Everyone else cleared out and Puropoker123 called, showing T♦ T♣; that was ahead of Armand2011's A♥ 9♣, and it stayed there through the K♥ 6♠ J♠ T♥ A♣ board, making Armand2011 the 9th-place finisher ($8,259.30).
Four hands later Puropoker123 seized a momentary chip lead after making a huge call with the tournament on the line. Facing a K♦ 5♥ K♣ 9♣ 4♠ board and an opponent who had three-bet in position preflop and subsequently fired three barrels, including an 880K bet on the river, Puropoker123 opted to call all-in with J♠ J♦. The jacks were good for the 2.95M-chip pot, as Poeira4 had been bluffing all along with J♥ 7♥.
That took the eight remaining players to their second break of the day. Upon returning to play with 25K/50K blinds and 6.25K antes, Festivuss once again doubled up to avoid elimination when 6♦ 6♣ held up against dsnka's A♥ T♣. Kora Fett then repeated the feat a few hands later, doubling up to 1.28M chips by cracking StigR's K♣ K♥ with A♦ K♠. After all that was done, StigR, who had entered the final second in chips, was the short stack with 505K - but moments later the Norwegian had cracked dsnka's K♣ K♠ with A♠ 6♥ to get back up to 1.06M.
The run-good streak for short stacks came to an end after Festivuss three-bet shoved for 834K in the small blind. Poeira4, who had opened for the minimum of 100K under the gun, called with A♥ Q♠ and promptly hit top pair on the Q♦ 4♠ 8♥ flop. That stayed ahead of Festivuss' 7♥ 7♦ through the T♥ turn and 9♣ river, making Festivuss the 8th-place finisher ($14,779.80).
StigR's wild ride continued two orbits later. Again at risk as an all-in short stack, StigR managed to get in ahead with A♣ K♠ against dsnka's A♠ T♥. Big Slick and the Norwegian once again crossed the 2-million-chip threshold just before the blinds went up to 30K/60K with a 7.5K ante.
As Level 40 began the remaining players were stacked like this:
Seat 1: Puropoker123 (3,280,651 in chips)
Seat 3: jenbizzle (1,538,434 in chips)
Seat 5: Kora Fett (1,006,626 in chips)
Seat 6: dsnka (1,003,725 in chips)
Seat 7: Poeira4 (2,663,723 in chips)
Seat 8: StigR (2,139,878 in chips)
Seat 9: samuraiUA (2,856,963 in chips)
After a wild run throughout Day 2, dsnka's tournament finally came to an end after the Czech player three-bet all-in from the big blind with T♥ T♠ and got a call from Kora Fett with 8♣ 8♥. The 9♦ J♠ 8♦ flop gave Kora Fett the lead but still dangled hope for dsnka in the form of outs to a straight. But the 3♦ turn and 4♠ river were no help, sending dsnka out in 7th place ($21,735).
Soon the blinds were raised to 40K/80K with a 10K ante. There was plenty of action from there, but it would be another three orbits before another major confrontation where neither player opted to back down. StigR, at the center of so much of the action during Day 2, was again involved. Poeira4 opened the action on the button for the minimum of 160K, and StigR responded with a three-bet to 254K in the small blind. Poeira4 opted to jam for 1.89M, and pretty quickly StigR called. The Norwegian showed A♥ J♥, which was coin-flipping with Poeira4's 8♥ 8♣. This time it was Poeira4 whose tournament life was on the line - and it was taken away after the board came 6♦ K♠ 9♦ A♦ T♦, making Poeira4 the 6th-place finisher ($30,429).
That pot left StigR with 4.62M, nearly 900K ahead of Puropoker123 and more than 2M ahead of the rest of the field. But as had so often happened already, the lead would quickly shift. First jenbizzle shoved for 1.76M under the gun with K♥ Q♥ and got a call from Puropoker123, holding A♠ K♠. The board fell 6♠ 3♠ J♥ A♥ 2♦, sending the 3.7M-chip pot to Puropoker123 and eliminating jenbizzle in 5th place ($39,123).
On the very next hand, StigR opened for the minimum on the button with 7♠ 7♣ and called after samuraiUA shoved from the small blind for 2.17M with A♣ 9♦. The board came 4♣ 5♥ 2♠ T♣ K♠, StigR took the 4.46M-chip pot and the chip lead, and samuraiUA left in 4th place ($53,902.80).
That left three players, stacked like so as the tournament went to its fourth and final break of the day with just a few minutes left at 40K/80K/10K:
Seat 1: Puropoker123 (6,165,131 in chips)
Seat 5: Kora Fett (2,112,661 in chips)
Seat 8: StigR (6,212,208 in chips)
Puropoker123 managed to come out ahead in two confrontations against StigR and another against Kora Fett before the blinds went up to 50K/100K with a 12.5K ante, enough to open up a 30-big-blind lead over StigR. That big stack paid off a few hands later when StigR folded the button and Puropoker123, holding K♠ 8♥, bet enough to put Kora Fett all-in and the short-stacked Canadian player called with A♣ 4♦. The gamble paid off for Puropoker123 when the board came 3♥ T♥ 8♠ 3♣ K♥, eliminating Kora Fett in 3rd place ($78,246).
It was Panama versus Norway in the final:
Seat 1: Puropoker123 (9,360,892 in chips)
Seat 8: StigR (5,129,108 in chips)
For StigR, it was the third opportunity in three years to finish off a big PokerStars tournament. Two previous chances had ended in second place - a Sunday 500 back in August of 2010 and Event 1-M of SCOOP 2011- and there had also been a third-place finish in last year's SCOOP-High Main Event. The Norwegian had an uphill climb ahead to reverse that trend and a tough opponent to overcome in the process.
Puropoker123 went on the attack immediately, and by the third hand of heads-up play StigR ended up all-in only to have the pot chopped when both players played sevens full of queens on the board. Three hands after that, StigR survived another all-in situation by flopping a set with pocket deuces, but Puropoker123 would soon bring the two players back close to even in this pot:
From there it was a tug-of-war for the chip lead, with neither player willing to let the other have anything easily. Though both had been willing to go for broke early on, the action soon settled into a steady back-and-forth affair. Things were so even, the two even ended up getting all their chips in the middle in one pot on the 60K/120K/15K level with the same pair - Puropoker123 with T♣ T♦, and StigR with T♥ T♠.
But all things come to an end, especially entertaining heads-up poker matches. The hand that tipped the scales was a perfect microcosm of the way all of Day 2 had progressed up to that point:
Left with not quite five big blinds, StigR called all-in on the next hand with 5♣ 4♥ but couldn't overcome Puropoker123's Q♦ T♣. It was another runner-up spot for StigR, but with $104,328 to help ease the pain. As for Puropoker123, the honor of being the first WCOOP win ever by a player from Panama came with the added bonus of a bankroll-boosting prize of $134,104.
WCOOP Event #46: $320 NL Hold'em [2X Chance]
$500,000 guaranteed prize pool
2,218 entrants, 680 re-buys, 288 places paid
$869,400 total prize pool
1st place: Puropoker123 (Panama) $139,104
2nd place: StigR (Norway) $104,328
3rd place: Kora Fett (Canada) $78,246
4th place: samuraiUA (Ukraine) $53,902.80
5th place: jenbizzle (United Kingdom) $39,123
6th place: Poeira4 (Portugal) $30,429
7th place: dsnka (Czech Republic) $21,735
8th place: Festivuss (Argentina) $14,779.80
9th place: Armando2011 (United Kingdom) $8,259.30
Puropoker123 has become the first player from Panama ever to win a WCOOP event. Check up on what other nations have produced winners, as well as all the other stats from this year's WCOOP and WCOOPs past, in their fully sortable glory over at the WCOOP stats page. And don't forget to clean your ears out with WCOOP Radio daily at 15:00 ET.
Jason Kirk is a Freelance Contributor to PokerStars Blog.


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Eartha Kitt, a sultry singer, dancer and actress who rose from South Carolina cotton fields to become an international symbol of elegance and sensuality, has died, a family spokesman said. She was 81.
Her career spanned six decades, from her start as a dancer with the famed Katherine Dunham troupe to cabarets and acting and singing on stage, in movies and on television. She persevered through an unhappy childhood as a mixed-race daughter of the South and made headlines in the 1960s for denouncing the Vietnam War during a visit to the White House....
Eartha Kitt, Sultry 'Santa Baby' Singer, Dies
I loved her so much! When I was a little girl I was crrrrazy about catwomen:
My father took me to see her perform when I was a little girl, and although I was enthralled by the spectacular woman onstage in her red beaded gown, I didn't realize who she was until she came over to our table and said, "Hello, little girrrl. Your fatherrr told me you want to meeeeet me." I went nuts--Catwoman actually spoke to me!
A huge influence on neo-burlesque:
And a song I danced to in strip joints literally hundreds of times:
An amazing fiery woman in every way.
Posted by Jo Weldon, Headmistress of The New York School of Burlesque, for burlesquedaily.blogspot.com.
Friday, December 26, 2008
Eartha Kitt Passes
1 comment:
I had the opportunity to see her perform at Cafe Carlyle a few months ago. I had no idea what to expect considering her age, but she was fierce-I told her so after the show. She seemed a little tired or agitated though and now I wonder if that was the sickness...
When she passed away I thought of you, so I hope you're okay.
- January 1, 2009 at 1:44 AM
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Politics essay which must be harvard referenced. An essay which should explain how Kant a political thinker completes Hobbes's theory of peace. Could you pleaseshowa clear understanding ofHobbes' theory ofpeace andhow Kant has changed thing. Also breifly look at other thinkers.
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Now, even though we are sure Sister Wives is coming back - maybe even in time for the Summer Solstice ( LMAO) - it will be interesting to see if they stay in the same timespot. Here's a Lourdes prediction: If Sister Wives is on some obscure weekday at an even more obscure broadcast time, chances are good there won't be a season 5.
But Peeps Love Sister Wives, Right???? Heck Yeah !!
Too bad the above tweet was not the Kodster's real answer. Kody has to be Kody, so his answer has to have that typical Kody arrogance mixed with child-like innocence:
Just when you think it's safe to go back on Twitter, Meri and Kody decide to play it cute:
So what's been up with Christine? Last week she was squinting and hurting, this week she goes on a dinner date with her Kody and Aspyn:
What, no mexican food? Bet Kody was happy about that! Wait a minute, I'm getting mixed signals. Was this restaurant in California or was just the pier? Next time, give us a street like Kody does! AND let us know how good it was! We like to read that kind of stuff on twitter!
Hey what's Robyn been up to lately?
But then Robyn carries the Darger lovefest a little too far with a fan:
Holy Moly! What are you thinking? Do you get a commission for 'suggesting' fans read a rival's (yes RIVAL) book before purchasing yours? Honey, learn from the Dargers. They sell DARGER and only DARGER 24/7. Sheeesh!!
Last but not least. Rosie O'Donnell learned that her talk show had been cancelled after only six months on the air. Meri and Janelle tried to cheer Rosie up.
Now THAT's a dinner party I would like to attend! Maybe she'll take the entire Brown family on one of her cruises! Hey, that's a good idea - Cruises for Polygamists! Looking for a Sister Wife? Meet the wife you always wanted on our Cruise Ship! CRUISE LIKE A POLYGAMIST!
Now this is interesting. Seems that wonderfully cryptic tweet from Christine (while sitting on a pier) can be explained by wonderfully enthusiastic tweets from daughter Aspyn...
Seems like a nice long vacation in the happiest place on earth...Makes you wonder...why now and will Robyn ever get to go with Kody to the happiest place on earth, too?
Wouldn't it be funny if Kody's and Meri's (and possibly other wives too) trips to Disneyland will be edited together to seem like the entire family vacationed at the same time? Not to mention they are probably killing two birds with one Kodestone - if this was a school week, maybe the parental units are being filmed visiting colleges/universities, which would explain the presence of Aspyn.
Let's discuss this, shall we?
So that's all for now, and remember, I Scour the Internet so You Don't Have To, everybody! (I hate ending a sentence with a preposition!)


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Farmhouse Cottage - Our Self Catering Annexe
Once a couple of stables and a workshop, this space has been converted into a warm , comfortable and contemporary space.
The "cottage" consists of a kitchen with a full size cooker, microwave, fridge/freezer, dishwasher and washing machine.
The living room contains the dining table & chairs and a large sofa & armchair.
Two bedrooms with ensuite facilities.
The first is decorated in calming lavender and pine. It has a double bed and leads to a luxury bathroom with a jacuzzi bath and over bath shower.
The second bedroom can be made up with either a king size bed or twin beds. This room also has a shower room.
Each of the bedrooms and the living room have a digital television. There is also a radio and CD player.
Cot and high chair available.
The annexe is positioned in a sheltered spot so that on most sunny days it should be possible to eat outside.


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Freezing strawberries preserves the tastes of summer for delicious berries to enjoy in smoothies or to add to baked goods all year long.
Because we have such a short window of time to enjoy fresh from the garden berries, I decided to keep on the strawberry theme again today.
My first round didn't seem to last long at all!! We had berries and whipped cream for dessert every night, I made a batch of freezer jam, used some in these delicious scones and froze the rest before they spoiled.
So that meant a trip back to the berry farm to load up on more!!
When you open up that container of jam and that wonderful, pure wonderful strawberry scent hits you, another batch of jam just had to be created. A quart was kept out for us to eat fresh and all the rest were frozen to be enjoyed in the middle of winter when the berries are expensive and have to travel so far that they have very little flavour left.
The process to freeze them is actually very simple but just requires a bit of time. Here's how:
Wash and hull the berries.
Lay them in a single layer on a parchment lined baking tray. Blot gently with paper towel to remove excess water. Be sure they are not touching each other so they freeze individually and not in a big messy clump.
Set trays in the freezer for a couple of hours.
When they are frozen, put into freezer bags, remove air and seal. Be sure to write the date on each bag. They will keep up to six months in the freezer.
All through the winter months you have delicious berries to add to smoothies or to incorporate into muffins or scones. If you run out of jam, you can even whip up a batch when the snow is flying outside!!


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Season's Call for Aloha Construction, Inc.
After a hectic early spring season of extreme hail, storms and high wind, many Northern Illinois homes and businesses were bombarded with damage. Aloha Construction, Inc. hopes to mend the roofing and siding damages, and looks forward for the upcoming seasons.
Aloha Construction currently serve all of Illinois and Southern Wisconsin after experiencing much growth since they have opened their local business in 2008. President and CEO of Aloha Construcion, Inc., David A. Farbaky states that, "Our growth is and always has been centered around making people feel more secure in their homes". Hoping to build their promise of creating secure, high quality homes, Aloha Construction will add interior restoration and remodeling services that'll be announced in early May. This brand new extension of their branch will be based near their Lake Zurich headquarters. Over 20,000 roofing and siding projects were finished this year as opposed to 7,000 in 2013.
Aloha Construction, Inc. is a family-owned business that now services the entire State of Illinois an Southern Wisconsin. The company consists of professionally bonded and insured General Contractors. The professional roofers follow an extremely thorough 9 step inspection process before proceeding to insure that all of the issues are identified. Employees that specialize in siding are certified through rigorous training at the Vinyl Siding Institute. Experts at roofing, siding and gutter cleaning or replacing, the company will launch their new interior restoration service that will focus on full bathroom remolding, kitchen, water extraction, natural disaster aide, basements and much more.


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Here at Sarchione Ford of Waynesburg, we know that the transportation that you choose for your daily errands helps set the tone for your workday. That is why we aim to house a massive variety of new Ford vehicles, used cars, and Certified Pre-Owned Ford cars for sale at our Waynesburg Ford dealership. Whether you travel to our dealership from Dover, Canton, Carrollton, or Minerva, our used car sales team is ready to work diligently to help you find reliable transportation at attractive prices for your daily pursuits.
One way that we make it easy for drivers like you to secure durable transportation is through our rotating selection of used featured vehicles. Our featured inventory represents many popular and new arrivals at competitive prices. We hand-pick each model to feature, giving you a great starting point for your used car search. Look through our featured vehicles to discover like-new models with low mileage from popular brands including Ford, Chevrolet, Hyundai, Ram, and more.
Whether you already have an idea which used Ford vehicle best matches your driving needs or you would like the opportunity to explore pre-owned models from other known auto brands, we strive to make it easy for you to sort through our inventory. Browse our used cars for sale, submit your request for information regarding the durability or features of your favorite pre-owned models, and set up a test drive at Sarchione Ford of Waynesburg today!
At Sarchione Ford of Waynesburg, we carry a quality selection of used cars for sale from the Ford brand and other well-known auto manufacturers. Our used car sales team invites you to browse our inventory by price, year, mileage, model, and more to discover the new-to-you vehicle of your dreams. We are delighted to serve Ohio drivers throughout the Carrollton, Dover, Minerva, and Canton region at our Waynesburg Ford dealership. Contact us soon to set up a time to test drive your favorite used cars!


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But proceed with caution, fellow Just Cause junkie: this is a "reveal trailer" in every sense of the term. It shows VERY LITTE. What it does show is of dubious nature in that it's not really clear if this is pre-rendered stuff, or some mind-blowing, super-next-gen engine of godlike graphical fidelity. It's likely the former, but my irrepressible childlike wonder (read: gullibility) has me hoping for the latter.
Check it out for yourself; you'll find it in all its fiery, explosive, Michael-Bay-channelling glory after the jump. Rico looks angry; a little too angry for a bloke who gets to zip around in a wing suit while blowing shit up. I guess some people are just never happy.
And if you're curious, the track playing in the trailer is a cover of Prodigy's "Firestarter". It's done by Torre Florim of the band De Staat. His music video is here, and the original Prodigy track is here. Hello nineties!


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Media Options
A Federal District Court judge will be hearing arguments today on a class action suit against Texaco brought about by indigenous communities from Ecuador's Amazon basin. The plaintiffs charge Texaco with ruining their rivers and land, causing widespread devastation to the rainforest environment and creating a dramatically increased risk of cancer for tens of thousands of people. According to attorneys, damages could exceed a billion dollars.
The case is being heard today by Judge Jed Rakoff, a Federal District Court judge who had dismissed the case earlier but had his decision overturned by a higher three-judge panel. Judge Rakoff is to decide whether the case will be tried in the U.S., or will be referred to Ecuadorian courts. Plaintiffs in the case are using an obscure law of the 1700's that was used to prosecute pirates, and if their legal tactics are successful, the case would set an important precedent for groups trying to sue companies for environmental damages in the countries where the companies are based.
- Joseph Kohn, lead attorney for the plaintiffs on the Texaco lawsuit.
- Chris Jochnik, Coordinator for Latin America at the Center for Economic and Social Rights, from Quito, Ecuador. Call: Center for Economic and Social Rights 212.634.3424.
Related links:


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Frequent Links
Ghrelin (pr. GREL-in), the "hunger hormone", is a peptide produced by ghrelin cells in the gastrointestinal tract[1][2] which functions as a neuropeptide in the central nervous system.[3] Beyond regulating hunger, ghrelin also plays a significant role in regulating the distribution and rate of use of energy.[4]
When the stomach is empty, ghrelin is secreted. When the stomach is stretched, secretion stops. It acts on hypothalamic brain cells both to increase hunger, and to increase gastric acid secretion and gastrointestinal motility to prepare the body for food intake.[5]
The receptor for ghrelin is found on the same cells in the brain as the receptor for leptin, the satiety hormone that has opposite effects from ghrelin.[6] Ghrelin also plays an important role in regulating reward perception in dopamine neurons that link the ventral tegmental area to the nucleus accumbens[7] (a site that plays a role in processing sexual desire, reward, and reinforcement, and in developing addictions) through its colocalized receptors and interaction with dopamine and acetylcholine.[3][8] Ghrelin is encoded by the GHRL gene and is presumably produced from the cleavage of the prepropeptide ghrelin/obestatin. Full-length preproghrelin is homologous to promotilin and both are members of the motilin family.
- 1 History and name
- 2 Gene, transcription products, and structure
- 3 Ghrelin cells
- 4 Function and mechanism of action
- 5 Blood levels
- 6 The ghrelin receptor
- 7 Sites of action
- 8 Immune system
- 9 Anorexia and obesity
- 10 Disease management
- 11 Future clinical uses
- 12 References
- 13 Further reading
History and name
Ghrelin was discovered after the ghrelin receptor (called growth hormone secretagogue type 1A receptor or GHSR) was discovered in 1996[9] and was reported in 1999.[10] The hormone name is based on its role as a growth hormone-releasing peptide, with reference to the Proto-Indo-European root ghre, meaning to grow.[11] (Growth Hormone Release-Inducing = Ghrelin)
Gene, transcription products, and structure
The GHRL gene produces mRNA which has four exons. Five products arise: the first is the 117-amino acid preproghrelin. (It is homologous to promotilin; both are members of the motilin family). It is cleaved to produce proghrelin which is cleaved to produce a 28-amino acid ghrelin (unacylated) and C-ghrelin(acylated). Obestatin is presumed to be cleaved from C-ghrelin.[12]
Ghrelin only becomes active when caprylic (octanoic) acid is linked posttranslationally to serine at the 3-position by the enzyme ghrelin O-acyltransferase (GOAT). It is located on the cell membrane of ghrelin cells in the stomach and pancreas.[13] The non-octanoylated form is desacyl ghrelin. It does not activate the GHSR receptor but does have other effects: cardiac,[14] anti-ghrelin,[15] appetite stimulation,[16] and inhibition of hepatic glucose output[17] Side-chains other than octanoyl have also been observed: these can also trigger the ghrelin receptor.[18] In particular, decanoyl ghrelin has been found to constitute a significant portion of circulating ghrelin in mice, but as of 2011 its presence in humans has not been established.[19]
Ghrelin cells
Alternate names
The ghrelin cell is also known as an A-like cell (pancreas), X-cell (for unknown function), X/A-like cell (rats), Epsilon cell (pancreas), P/D sub 1 cell (humans) and Gr cell (abbreviation for ghrelin cell).[20]
Ghrelin cells are found mainly in the stomach [21] and duodenum, but also in the jejunum, lungs, pancreatic islets,[22] gonads, adrenal cortex, placenta, and kidney.
Ghrelin cells are found in oxyntic glands (20% of cells),[23] pyloric glands, and small intestine. They are ovoid cells with granules.[24] They have gastrin receptors.[25] They produce nesfatin-1, another food intake limiting hormone in addition to ghrelin.[26] Ghrelin cells are not terminally differentiated in the pancreas: they are progenitor cells that can give rise to A-cells, PP cells and Beta-cells there.[27]
Function and mechanism of action
Ghrelin is a participant in regulating the complex process of energy homeostasis which adjusts both energy input - by adjusting hunger signals - and energy output - by adjusting the proportion of energy going to ATP production, fat storage, glycogen storage, and short-term heat loss (all energy input is ultimately dissipated as heat). The net result of these processes is reflected in body weight, and is under continuous monitoring and adjustment based on metabolic signals and needs. At any given moment in time, it may be in equilibrium or disequilibrium. Gastric-brain communication is an essential part of energy homeostasis, and several communication pathways are probable, including the gastric intracellular mTOR/S6K1 pathway mediating the interaction among ghrelin, nesfatin and endocannabinoid gastric systems,[28] and both afferent and efferent vagal signals.
Ghrelin and synthetic ghrelin mimetics (the growth hormone secretagogues) increase appetite and fat mass[29][30] by triggering receptors in the arcuate nucleus[31][32] that include the orexigenic neuropeptide Y (NPY) neurons.[33] Ghrelin-responsiveness of these neurons is both leptin- and insulin-sensitive.[34] Ghrelin reduces the mechanosensitivity of gastric vagal afferents, so they are less sensitive to gastric distension.[35]
In addition to its function in energy homeostasis, ghrelin also activates the mesolimbic cholinergic–dopaminergic reward link, a circuit that communicates the hedonic and reinforcing aspects of natural rewards, such as food and addictive drugs such as ethanol.[34][36][37] Ghrelin receptors are located on neurons in this circuit.[7] Hypothalamic ghrelin signalling is required for reward from alcohol[38] and palatable/rewarding foods.[39][40]
Ghrelin also improves endothelial function and inhibits proatherogenic changes in cell cultures. It activates the endothelial isoform of nitric oxide synthase in a pathway that depends on various kinases including Akt.[41]
Ghrelin has been linked to inducing appetite and feeding behaviors. Circulating ghrelin levels are the highest right before a meal and the lowest right after.[42] Injections of ghrelin in both humans and rats have been shown to increase food intake in a dose-dependent manner.[43] So the more ghrelin that is injected the more food that is consumed. However, ghrelin does not increase meal size, only meal number.[44] Ghrelin injections also increase an animal's motivation to seek out food, behaviors including increased sniffing, foraging for food, and hoarding food. Body weight is regulated through energy balance, the amount of energy taken in versus the amount of energy expended over an extended period of time. Studies have shown that ghrelin levels are negatively correlated with weight. This data suggests that ghrelin functions as an adiposity signal, a messenger between the body's energy stores and the brain.[5] When a person loses weight their ghrelin levels increase, which causes increased food consumption and weight gain. On the other hand, when a person gains weight, ghrelin levels drop, leading to a decrease in food consumption and weight loss. This suggests that ghrelin acts as a body weight regulator, continuously keeping one's body weight and energy stores in check.
Blood levels
Blood levels are in the pmol/l range. Both active and total ghrelin can be measured.[45] Circulating ghrelin concentrations rise before eating and fall afterward, more strongly in response to protein and carbohydrate than to lipids.[19]
The ghrelin receptor
The ghrelin receptor GHSR1a (a splice-variant of the growth hormone secretagogue receptor) is involved in mediating a wide variety of biological effects of ghrelin, including: stimulation of growth hormone release, increase in hunger, modulation of glucose and lipid metabolism, regulation of gastrointestinal motility and secretion, protection of neuronal and cardiovascular cells, and regulation of immune function.[46] They are present in high density in the hypothalamus and pituitary, on the vagus nerve (on both afferent cell bodies and afferent nerve endings) and throughout the gastrointestinal tract.[13][35]
Sites of action
Gastrointestinal tract
Ghrelin promotes intestinal cell proliferation and inhibits apoptosis during inflammatory states and oxidative stress.[47][48] It also suppresses pro-inflammatory mechanisms and augments anti-inflammatory mechanisms, thus creating a possibility of its therapeutic use in various gastrointestinal inflammatory conditions, including colitis, ischemia reperfusion injury, and sepsis.[49][50] Animal models of colitis, ischemia reperfusion, and sepsis-related gut dysfunction have been shown to benefit from therapeutic doses of ghrelin.[49][50] It has also been shown to have regenerative capacity and is beneficial in mucosal injury to the stomach.[51]
Ghrelin promotes gastrointestinal and pancreatic malignancy.[52][53][54]
Ghrelin acts on its receptor in the pancreas to inhibit glucose-stimulated insulin secretion.[55]
Glucose metabolism
The entire ghrelin system (dAG, AG, GHSR and GOAT) has a gluco-regulatory action.[55]
Nervous system
Learning and memory
The hippocampus plays a significant role in neurotrophy: the cognitive adaptation to changing environments and the process of learning[56][57] and it is a potent stimulator of growth hormone.[10] Animal models indicate that ghrelin may enter the hippocampus from the bloodstream, altering nerve-cell connections, and so altering learning and memory. It is suggested that learning may be best during the day and when the stomach is empty, since ghrelin levels are higher at these times. A similar effect on human memory performance is possible.[56] In rodents, X/A-like cells produce ghrelin.[58]
Ghrelin knock-out mice (who never express ghrelin) have increased anxiety in response to a variety of stressors, such as acute restraint stress and social stress in experimental settings.[59] In normal mice, ghrelin can stimulate the hypothalamic-pituitary-adrenal axis, from the anterior pituitary.[59]
Ghrelin has been shown to have implications for depression prevention. Antidepressant-like attributes were demonstrated when mice with high levels of ghrelin and mice with the ghrelin gene knocked out underwent social defeat stress and then were placed in the forced swim tank. Mice with elevated ghrelin swam more than ghrelin deficient mice.[60] These ghrelin-deficient mice exhibited more social avoidance as well. These mice did not exhibit depression-like behaviors when injected with a commonly prescribed antidepressant, suggesting that ghrelin acts as a short-term natural adaptation against depression.
Sleep duration
Short sleep duration is associated with high levels of ghrelin and obesity. An inverse relationship between the hours of sleep and blood plasma concentrations of ghrelin exists; as the hours of sleep increase, ghrelin levels trend lower and obesity is less likely.[61]
Stress-induced fear
Prior stress exposure heightens fear learning during Pavlovian fear conditioning. Stress-related increases in ghrelin circulation were shown to be necessary and sufficient for stress to increase fear learning. Ghrelin was found to be upregulated by stress even in the absence of adrenal hormones. Blocking the ghrelin receptor during stress abolished stress-related enhancement of fear memory without blunting other markers of stress. These results suggest that ghrelin is a novel branch of the stress response.[62] Human studies are needed to translate the use of anti-ghrelin treatments to prevent stress-induced psychiatric disorders.
Substantia nigra function
Ghrelin, through its receptor increases the concentration of dopamine in the substantia nigra.[63]
Reproductive system
Ghrelin has inhibitory effects on gonadotropin-releasing hormone (GnRH) secretion. It may cause decreased fertility.[64]
Fetus and neonate
- Ghrelin is produced early by the fetal lung and promotes lung growth.[65]
- Cord blood levels of active and total ghrelin show a correlation between ghrelin levels and birth weight.[45]
Immune system
Ghrelin gene products have several actions on acute and chronic inflammation and autoimmunity, with promising therapeutic applications.[66]
Anorexia and obesity
- Ghrelin levels in the plasma of obese individuals are lower than those in leaner individuals,[67] suggesting that ghrelin does not contribute to obesity, except in the cases of Prader-Willi syndrome-induced obesity, where high ghrelin levels are correlated with increased food intake.[68][69]
- Those with anorexia nervosa have high plasma levels of ghrelin[70] compared to both the constitutionally thin and normal-weight controls.[71]
- The level of ghrelin increases during the time of day from midnight to dawn in thinner people, which suggests there is a flaw in the circadian rhythm of obese individuals.[72]
- Ghrelin levels reflect release in a circadian rhythm which can be interrupted by exposure to light at night.[73]
- Short sleep duration may also lead to obesity, through an increase of appetite via hormonal changes.[74]
- Lack of sleep increases ghrelin, and decreases leptin, both effects producing increased hunger and obesity.
- Ghrelin levels are high in patients with cancer-induced cachexia.[75]
Disease management
Gastric bypass surgery
Gastric bypass surgery not only reduces the gut's capacity for food but also dramatically lowers ghrelin levels compared to both lean controls and those that lost weight through dieting alone.[67] However, studies are conflicting as to whether or not ghrelin levels return to nearly normal with gastric bypass patients in the long term after weight loss has stabilized.[76] Bariatric surgeries involving vertical sleeve gastrectomy reduce plasma ghrelin levels by about 60% in the long term.[77]
Medical management of obesity
Ghrelin is not FDA approved for any indication. In rodents and pigs, an anti-obesity vaccine has been developed: it blocks the ghrelin receptor.[78][79]
Future clinical uses
- Synthetic ghrelin administration for cachexia of any cause [80] and for hemodialysis patients[81] is being investigated.
- Ghrelin suppresses seizures in animal models and is being investigated.[82]
- Ghrelin is a gastric pro-kinetic and may be useful in the treatment of gastroparesis.[83]
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The best described site of action of ghrelin is the VMH and arcuate nucleus, but ghrelin receptors are also expressed in the brain's reward pathways (eg, VTA dopamine neurons) and may stimulate feeding through this action as well. ... It is very interesting then, as mentioned above, that orexin, leptin, and ghrelin receptors are expressed in the VTA, and MC4 and MCH receptors are enriched in the nucleus accumbens. There is increasing evidence that some of the actions of these feeding peptides are mediated at the level of the VTA-NAc circuit: recent studies, for example, have shown that injection of leptin into the VTA suppresses feeding behavior, while RNAi (RNA interference; Chapter 4) mediated-knockdown of leptin receptors in the VTA increases food intake, sensitivity to highly palatable foods, and locomotor activity.
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Further reading
- Meyer RM, Burgos-Robles A, Liu E, Correia SS, Goosens KA (Dec 2014). "A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear". Molecular Psychiatry 19 (12): 1284–94. PMC 3988273. PMID 24126924. doi:10.1038/mp.2013.135.
- Dickson SL (Jan 2002). "Ghrelin: a newly discovered hormone". Journal of Neuroendocrinology 14 (1): 83–4. PMID 11903816.
- Bown R (3 September 2006). "Ghrelin". Pathophysiology of the Endocrine System. Colorado State University. Retrieved 18 September 2008.
- Burstain T (1 January 2005). "Balancing Your Hunger Hormones". Web site reviewing role of ghrelin and leptin in obesity. Infinity Medical Systems, Inc. Retrieved 18 September 2008.
- Shea C (10 December 2006). = 1&scp = 1&sq = Empty-Stomach+Intelligence&st = nyt&oref = slogin "Empty-Stomach Intelligence". New York Times. Retrieved 18 September 2008.
- Raloff J (April 2005). "Still Hungry? Fattening revelations—and new mysteries—about the hunger hormone". Science News (ScienceNews.org) 167 (14): 216–220. JSTOR 4016366. doi:10.2307/4016366.
- Nixon R (14 July 2008). "Feeling hungry can make you happy". Mental health (MSNBC.com). Retrieved 18 September 2008.


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Buy Sedum Flat Green Roof Kit
When you order Enviromat online you can be assured of the very best service, value for money and product quality.
Winter cancellation policy
Please note that between November and March we are unable to accept order cancellations at less than 2 working days notice. (this is to keep our labour costs down).
Enviromat Sedum Flat Green Roof KitA living sedum roof on a flat roof that can be installed in an afternoon. This kit will instantly enhance any sturdy building with a roof pitch of 3 degrees or less. Learn More
Enviromat Natural Green Roof Feed£14.40Keep green roof plants healthy with this balanced feed made entirely from natural ingredients. Specially formulated for living roofs, this easy to apply granular feed is an essential part of our recommended green roof maintenance regime. Learn More


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Meet and greet party post
I am going to the meet and greet party that Dog tipper is having. You should come too. A short introduction of me. I am Roxy the traveling dog, and I have so much fun! I travel with my mom and dad, Al and Mary Hone. We go camping, to art shows, and to mountain man rendezvous. That's where I am right now. We like rendezvous, so much to do, great people to meet. The art shows are fun too. Dad is a great artist, and mom makes beautiful bead work. So we get to see fun stuff and meet nice people at the shows too. One of my favorite things is to go hiking. I can hike pretty far on my little legs. My sister Torrey is 6 months old, and all this traveling is new to her. She is having a great time. Follow us on facebook https://www.facebook.com/pages/Roxy-the-traveling-dog/103654976377767 Or on twitter http://twitter.com/#!/RoxyTrvlingDog
It's all about the fun!!
It's all about the fun!!


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Iron Throne 2000
Maybe it's just my ears messing with me …
Black Knight 2000 Metal Edition!
The Black Knight is here! With METAL! So … LISTEN you KNAVE!
Black Knight 2000 – Main Theme Guitar Cover by RetroGeet
Retrogeet's cover of Judge Dredd was awesome! Let's increase the big damage with his cover of Black Knight 2000!
Pinball makes the list! [MUSIC]
Kotaku posted a video with their opinion of the 5 best game songs that most people haven't heard. Guess what made the list…
Steve Ritchie games led to the ESRB?
Scott Bromley's Internet Rabbit Hole makes the connections between Superman pinball from Atari, twin stick shooters and the ESRB videogame rating system… and it actually makes sense.
Black Knight 2000 for The Pinball Arcade released!
BK2K is out for PC and portables! It's a celebration! Black Power 2000 mashup by DJ Dain! Abbreviated cover of the main theme by: Dr. Rockyowitz.
Soundtrack Spotlight: Black Knight 2000
Give me your money! I need it to buy Beats by Dre.