text:
Year of release: 2003
Genre: Progressive Rock/Metal
Country: Poland
Genre: Progressive Rock/Metal
Country: Poland
01. The Same River
02. Out Of Myself
03. I Believe
04. Reality Dream
05. Loose Heart
06. Reality Dream II
07. In Two Minds
08. The Curtain Falls
In a few words:
This Polish band came out of nowhere in 2003, and with this excellent debut made a lot of noise in the prog rock/metal fans all over the world. The album balances between prog metal (in riffs) and rock (in solos), while it is simultaneously very atmospheric. In its heavy moments it reminds me Pain Of Salvation, while in the quite moments, and especially at solos, I detect a Pink Floyd influence.
Personal highlights:
"Out Of Myself", "Reality Dream" and "OK"


text:
Hive FM: Important Questionson January 18, 2013
I think this is the most important interview question! There should also be time to ask if you're one of those people who says "bless you" EVERY time someone sneezes or just the first time each day, because man that would drive me nuts, I don't care if you work hard or not just don't say it EVERY time Jesus tapdancing Christ on rollerblades people.
[ 2 Comments ]

subset: commoncrawl


text:
Yahoo's headaches don't seem to subside.
The troubled Web search and services company is on the defensive against one of its largest stockholders, hedge fund director Daniel Loeb, who did some research and found that the company's new CEO, Scott Thompson, didn't earn a degree in computer science as his resume states. Yahoo also used the misinformation in a regulatory filing with the SEC last week.
Thompson (pictured), who replaced Carol Bartz four months ago as CEO, attended Stonehill College in Easton, Mass., and attained an accounting degree there in 1979, according to the institution's Website. Stonehill didn't offer a computer science degree when Thompson was an undergraduate, Loeb said.
Yahoo confirmed Loeb's accusation on May 3, saying that it was an "inadvertent error" and that the incorrect information "in no way alters that fact that Mr. Thompson is a highly qualified executive with a successful track record leading large consumer technology companies."
Further reading
Yahoo's board of directors now will review Thompson's background, a company spokesman told Reuters. Yahoo will also make an appropriate disclosure to shareholders when the review is complete, the spokesman said.
Other companies have suspended or fired executives who were caught falsifying their resumes.
Thompson was CEO of PayPal and was named Ernst & Young Entrepreneur of the Year in 2011 before moving to Yahoo in January.
Shareholder Has an Agenda
Loeb, whose Third Point private equity firm owns a 5.8 percent stake in Yahoo, hasn't been satisfied with the company's financial performance and has had an agenda for a while against the Yahoo leadership. Not only does he want Thompson to be ousted, he also wants the entire board of directors to go--including the head of the search committee that selected Thompson, board member Patti Hart.
"If Mr. Thompson embellished his academic credentials, we think that it 1) undermines his credibility as a technology expert, and 2) reflects poorly on the character of the CEO who has been tasked with leading Yahoo at this critical juncture," Loeb wrote in a letter to Yahoo's board. "Now more than ever Yahoo investors need a trustworthy CEO."
Loeb said the mix-up was an example of Yahoo's poor corporate governance and described the misinformation as a violation of Yahoo's code of ethics. He also called for an independent investigation to find out if Thompson had purposely misled the board about his technology credentials.
Yahoo recruited Thompson to rescue it from years of financial setbacks that have dogged the company, despite the fact that advertising dollars have been increasing for the Internet. Yahoo's stock, which has been selling in the $10 to $20 range for several years, closed at $15.40 on May 3.
The stock was selling for more than $33 in 2008 when Microsoft offered to buy the company for $47 billion, an action that was opposed by former longtime board chairman Roy Bostock, co-founder Jerry Yang and a majority of the board in spring 2008.
Turnover on the Board
Yahoo, once the leading search engine on the Internet, has been struggling for about 10 years. On Feb. 8, four members of the Yahoo board, including Bostock, resigned under pressure from shareholders.
For about seven years, Yahoo ranked as the world's No. 1 Internet search engine. However, Google bypassed it in general usage in about 2002. Facebook, Twitter and other social media services also have taken page views from Yahoo, which is still the No. 2 search provider and whose Yahoo Mail is the world's leading Webmail application.
Yahoo's search engine never has been able to work as quickly or as efficiently as Google's, and it has paid a steep price for being surpassed. It also has not been able to get as much traction as Google and other Web service providers on features such as Web documents, collaboration tools, calendaring, texting and others.
Chris Preimesberger is eWEEK's Editor for Features and Analysis. Twitter: @editingwhiz


text:
5.1 patch notes and news galore, and Alludra and Kephas are silly-ing the place up! Now with fun dance time and more shenanigans! How many words did we mess up this show!
Also for added fun, why don't you try sending us you messing up the phrase: General purpose Polished Battle-stones can be purchased for 1000 Justice Points.
Love to see it!
Patch note information can be found here. (show recorded from the October 23 notes)


text:
Ramsons Extract / Tincture (4oz/118ml) - Maria Treben's Authentic™
Every spring brings new hope and warmth. We feel joy and our thoughts have wings, we are pleased about the first sign of green, the singing of the birds and feel with our whole heart that all this is a gift of our Creator. The green, shiny broad leaves are very similar to those of the Lily-of-the-Valley. They grow from an elongated bulb, which is surrounded by layers of clear skin. The smooth, light-green stern, with its head of white flowers, grows to a height of 30 cm. Ramsons grows only in shady and damp woods. Its pungent garlic odour that has given it the name of Wild Garlic, is smelled long before the plants are sighted and prevents them from being mistaken for the Lilly-of-the-Valley or the Meadow Saffron (Colchicum autumnale). In early Spring, many damp woods are densely carpeted with the fresh green leaves of Ramsons. They start to grow in April and May, sometimes earlier, the flowers from May to June. bears, after hibernation, seek it out to cleanse their system. The leaves are used fresh. They are finely chopped and laid on buttered bread, used uncooked as a seasoning in the daily soup and added to potatoes, dumplings and other foods, where normally Parsley is used. The leaves can also be prepared like spinach or salad. Since they have a biting taste when used in large amounts, they should be mixed with Stinging Nettle leaves when prepared as a spinach dish. The young leaves are gathered in April and May before the time of flowering, the bulbs in late summer and autumn. These bulbs can be used the same way as garlic. People who have a sensitive stomach should pour warm milk over the finely chopped leaves and bulbs, infuse them for two to three hours and sip this liquid.
Seasoning: Fresh leaves, finely chopped like chives or parsley, are sprinkled on bread, in soups, sauces, salads and meat dishes.
Ramsons' spirit: A bottle is loosely filled to the neck with finely chopped leaves or bulbs, which are covered with 38% to 40% rye whisky or other grain alcohol and placed in the sun or near the stove for 14 days. 10 to 15 drops are taken in water 4 times daily.
Ramsons' wine: A handful of finely chopped leaves is boiled for a short time in approx. 1/4 litre of white wine, sweetened to taste with honey or syrup and sipped slowly.


text:
2009-08-29 templates/xml* docs/nikto.dtd
- Added tag for scan/host statistics
2009-08-25 plugins/db_httpoptions
- Fix for #89 - remove TRACE and TRACK from the db
2009-08-19 plugins/nikto_headers
- Added test for asp source code disclosure through the Translate
2009-08-13 plugins/* plugins/nikto_embedded plugins/db_embedded
- Various fixes to use nfetch and fix proxy use
- New plugin added to identify embedded devices
2009-08-12 plugins/nikto_core
- New fetch (nfetch) sub added which uses a local request/result hash.
All requests should use this instead of fetch.
- Patch to add a URI cache within fetch, can be disabled with -nocache
2009-08-04 plugins/nikto_core
- Patch to actually report the URI when it works out a password
- Added test for DEBUG HTTP verb
2009-08-03 plugins/nikto.pl
- Put in a quick catch for port ranges (e.g. 80-90) if people use the
old style of port entries
- Put in a simple signal handler to close reporting if a sigint is
2009-08-02 plugins/nikto_multiple_index db_multiple_index
- Added check for multiple index files for request #16
- Turned standard headers into a database file to close off #22
2009-08-01 plugins/* nikto.pl
- Fixes for xml reporter to allow multiple hosts
- Fixes for html, txt and csv exporters
- Fixes bugs #80 and #85
2009-07-31 plugins/* nikto.pl
- Fix for ePO agent/HP iLO to not report for each known type of
- Big changes to the way nikto assigns targets to remove globals, have
deliberately broken nmap scanning and allowing port ranges.
2009-07-20 plugins/nikto_core plugins/nikto_outdated db_tests db_outdated
- Fix to ensure that -Tuning works as expected, fixes ticket #84
- Fix to add a warning if a web server has been configured to restrict
information on its server banner, fixes ticket #66
- Minor amendment to lightttpd version to fix ticket #67
- Fix to nikto_core to make dbcheck work!
- New item for ticket #75
2009-06-30 plugins/nikto_dictionary_attack
- Add plugin to use dirbuster lists with mutate 6 and mutate-options
- couple of minor fixes to prevent errors on Windows and exporting as
2009-06-27 plugins/nikto_user_enum_cgiwrap.plugin
- Managled cgiwrap and apache plugins together and allow use of a
dictionary (to speed things up). Also made it work with new
reporting style
- Added -mutate-options switch
2009-06-15 plugins/nikto_reports.plugin templates/xml_end
- Fixed bug with xml not terminating correctly
2009-05-11 plugins/nikto_core.plugin plugins/nikto_subdomain.plugin
- Added subdomain buteforcer as mutate option 5, thanks to Ryan
- Added extra tests to pull information if scanning ePO agent or HP
- Added test to recognise a Dell Remote Access Console
- Added -no404 switch to disable 404 checking. Warning, this produces
a lot of false positives at the moment
2009-01-10 plugins/nikto_core.plugin
- Added fix for #73 to apply multiple variables for tests, supplied by
Laurent Licour
- Removed test_target function as now done in the nikto_test plugin
- Added support for Allow directive in robots.txt
- Added exit if cannot connect to a defined proxy
2008-11-11 plugins/nikto_core.plugin nikto.pl plugins/nikto_reports.plugin
- Added report phase to plugin runner
2008-10-09 plugins/nikto_core.plugin nikto.pl
- Further tunings to authentication code to simplify it.
2008-10-02 plugins/nikto_core.plugin nikto.pl
- Altered authentication code to make it simpler.
- Now supports NTLM authentication.
2008-09-24 plugins/nikto_core.plugin db_tets
- Fixed problem with nikto using authentication provided from the
command line. It now adds it to the list of realms.
- Added extra test to highlight localstart.asp if it is the default
- Added tests to identify Ampache.
2008-09-23 plugins/*.plugin
- Added support for conditional recon and scan plugins.
2008-09-21 plugins/*.plugin
- Changes for new plugin running structure; it needs to be finished
(conditional plugins and report methods) but it is good enough to
release now.
2008-09-20 plugins/nikto_core.plugin plugins/nikto_cgi.plugin nikto.pl
plugins/nikto_reports.plugin templates/xml_host_head.tmpl
- Fixes to ensure nikto produces less perl warnings
- Fix for ticket #59: add vhost to xml output
2008-09-16 plugins/nikto_core.plugin plugins/nikto_httpoptions.plugin
- Fix for ticket #37
- Allow fetch to optionally call LW2::http_fixup_request
- Better handling of extra headers within fetch
2008-09-14 plugins/db_server_msgs plugins/nikto_*.plugin
- Update server messages to dynamic database format
- Altered all plugins to use a separate RESULTS array for storing
results; meaning that it is easier to abstract
- Added add_vulnerability method to nikto_core to report
vulnerabilities and reduce code size.
- Added ability to add an extra hash to fetch() to allow extra headers
to be added.
2008-09-12 plugins/nikto_core.plugin plugins/nikto_httpoptions.plugin
plugins/db_httpoptions plugins/nikto_favicon plugins/db_favicon
- Fix for ticket #38: httpoptions are drawn from a database
- Now setup to allow dynamic databases, rather than all being imported
by nikto_core at start time
- Altered favicon database to use dynamic database
2008-09-06 plugins/nikto_core.plugin tmpl/htm_close.tmpl
- Fix for ticket #53: all plugins now show last mod date
- Fix for ticket #51: updated copyright date in HTML
2008-09-04 plugins/nikto_core.plugin
- Fix for ticket #55, introduced by the solution for ticket #44
- Fix for ticket #53
=========Nikto 2.03=========
2008-08-12 plugins/db_outdated
- Fix for Jetty to latest version, fixes ticket #49
2008-08-07 docs/nikto_manual.html
- New export of the manual from the docbook
- Updated versions in nikto.pl
2008-08-06 plugins/db_outdated
- Added various new versions
2008-08-05 plugins/db_favicon
- Fix for ticket #45
- Added favicons for Roku Soundbridge and Ampache
2008-07-14 plugins/nikto_headers.plugin
- Changes to look at non-standard headers
- Changes to examine Apache's ETag header
2008-07-07 nikto.pl plugins/nikto_core.plugin plugins/nikto_reports.plugin
- Fix for ticket #41 - a rather nasty bug that's been in nikto 2 since
its inception; where variables weren't fully expanded.
2008-07-02 plugins/nikto_core.plugin
- Fix for ticket #11 - change CGIDIRS test so that they're not
hardcoded. The reponse codes are now kept in a variable in
- Applied same to enumerating apache users plugin
- Fix for ticket #39 - we now check whether getoptions failed, show
usage and exit with a code of one. This also means that it will exit
gracefully if a parameter is missed out when one is required.
2008-06-24 plugins/nikto_core.plugin
- Fix for ticket #35 - allow multiple HTTP methods to identify
an HTTP server, these are set with the variable CHECKMETHODS in
- Fix for a bug in the nmap reader where it would ignore the IP
address if it nmap didn't return a hostname.
2008-06-22 plugins/db_tests
- Fix for ticket #26 - stop domino tests producing false positives
2008-06-20 plugins/nikto_httpoptions.plugin
- Fix for ticket #30 - ensure that propfind has the right OSVDB tag
2008-04-22 plugins/nikto_outdated.plugin
- Change to allow stop duplication of items when scanning more than one
host. Fix for bug 28
2008-04-16 plugins/nikto_core.plugin
- Change to allow reading of a host list from stdin
- Fix for enhancement 10: read from nmap output (only -oG)
2008-04-15 plugins/nikto_core.plugin
- Fixes for bug 25: Unopen ports are now reported
2008-04-14 templates/htm*
- Fixes for bug 24: HTML output is now valid HTML 4.01 Strict
2008-04-11 nikto.pl
- Started using international dates instead of the weird US format
- Added a fix for bug id 23: allow a range of ports instead of a comma
separated list
2008-04-11 db_outdated
- Updated current version of Apache to 2.2.8
01.06.2008 2.02
- Added XML output thanks to the work of Jabra. XML format comes from templates (same as HTML). See the 'templates' dir for more info.
- HTML reports changed by Jabra to remove some oddities and remove HTML from items
- Fixed non-reporting of non-HTTP ports (or closed ports) when at least one port was HTTP.
- Removed experimental knowledge base (KB) code, as XML output is more flexible for long-term scan tracking
- Added unique identifiers to all tests from databases, and all tests created in code
- Updated documentation
01.02.2008 nikto_core
- Fixed improper parsing of long options (-update, etc.). Thanks to Frank Breedijk for figuring this out.
12.30.2007 db_servers
- Removed as it is not used
12.19.2007 nikto_msgs.plugin
- Add a boundary for regex on versions to cut down false positives
12.19.2007 niko_favicon.plugin
- Added OSVDB ID
12.18.2007 niko_favicon.plugin
- Fix false positive when favicon.ico doesn't exist
11.22.2007 Nikto 2.01 release
- Fix anti ids encoding use. thanks to Francisco Amato
- Fix virtual host usage if set via CLI. thanks Jon Hart
- Fix Host header restoration when testing for IIS IP leak
- Fix for plugindir & templatedir if EXECDIR is set in config.txt, thanks Shiraishi.M and Will Andrews for pointing it out.
- Fix count of items--count now accurately reflects the number of items, not just number of vulns. thanks Frank Breedijk
- Kick a few more things to KB that should be saved
- Added SKIPIDS to config.txt to completely ignore some tests loaded from db_tests. Suggested by Christian Folini.
- Enhanced rm_active_content to try to exclude the file/QUERYSTRING requested
- Unset the auth header after guessing at it. Thanks Paul Woroshow for reporting the bug.
11.12.2007 nikto_headers.plugin
- Fix internal IP address snarfing for IIS, thanks Frank Breedijk for pointing it out
11.10.2007 Nikto 2.00 release
- Rewrite of nikto_httpoptions.plugin to read the Public header
- Fixups to prevent namespace violations in nikto.pl and nikto_core.plugin
- Add some normalizations to the -root option variable, suggested by Erik Cabetas
- Added -Display with options for suppressing redirects & cookies from being included in output
- Added -Tuning options to let users specify what they would like to test, or exclude certain categories
- Added config.txt's NMAPOPTS, thanks Sean Lewis for the suggestion
- All new HTML report
- Bugfix: a found cookie would report for every port/server after it was found
- Bugfix: all hosts scanned with all ports if hosts file used
- Bugfix: all hosts scanned with port 80 despite what the user wanted
- Bugfix: Reverse DNS inet_aton error fix, pointed out by Jason Peel @ Foundstone
- Changed auth checking so it will test any directory found, not just /, and removed nikto_realms.plugin as a consequence
- Changed scan_database.db format significantly (and name), (and all the code to deal with tests)
- Completely new 404 engine which causes less false-positives (see docs)
- Created dump_lw_hash instead of dump_request_hash & dump_result_hash
- Implemented a knowledge base which (should) store all the gory details of scans... probably use this later ;)
- Moved pre-defined variables from config.txt to variables.db so they can be automagically updated. Entries in config.txt are still read.
- Removed %CFG, storing vars in %NIKTO instead
- Removed -generic
- Removed extraneous global vars
- Removed load_realms, combined with load_variables
- Replaced %CONFIG with %NIKTOCONFIG
- Set MAX_WARN to trigger on any response code, skipping 404|403|401|400 to avoid common ones
- Added -Single single request mode
- Updates to use the RFP's LibWhisker 2.0
- Added -Help to show extended help ouput, changed default help screen to be shorter. Suggested by Jericho.
- Additional error checking on invalid reverse-dns (Paul Woroshow)
- Cleaned up comment/line parsing routines in multiple places, from Erik Cabetas
- Tightened some for loops with real values instead of guessing, from Erik Cabetas
- Addded error message if no host is specified, from Erik Cabetas
- Added more robust output file type checking (txt/htm/cvs), from Erik Cabetas
- Added more debug statements regarding which CGI directories will be scanned, from Erik Cabatas
- Bugfix: more 'half dead host' scanning issues resolved with Jericho. LW is much pickier now about calling http_close
- Added error if -F specified without -o, from Erik Cabetas
- Bugfix: server category match no longer matches partial strings, from Erik Cabetas
- Bugfix: mis-pasted line, pointed to by Erik Cabetas
- Send all errors to STDERR
- Added -config option to specify a config file, thanks to Pavel Kankovsky
- fixed regex issue on banner. thanks Alexander Ehlert for pointing it out
- All other plugins updated for v2 changes
- Added favicon.ico hash checking
- ... gobs more
02.06.2004 nikto_core.plugin 1.21
- Cleaned up comment/line parsing routines in multiple places, from Erik Cabetas
- Tightened some for loops with real values instead of guessing, from from Erik Cabetas
- Removed duplicate bit of code, from Erik Cabetas
- Addded error message if no host is specified, from Erik Cabetas
- Added more robust output file type checking (txt/htm/cvs), from Erik Cabetas
- Added more debug statements regarding which CGI directories will be scanned, from Erik Cabatas
nikto_core.plugin 1.20
- Fixed BID links, thanks Richard Tortorella for the report.
10.27.2003 Nikto 1.32 release
nikto_core.plugin 1.19
- Removed unecessary 'use IO::Socket' call from resolve()
- Removed unecessary counters
- Replaced some slow foreach counters
- Moved proxy_check earlier, before port_scan, so it will be set first
- Removed -allcgi option in favor of -CGIdir, which can specify to test 'all', 'none' or a specific directory.
- Bugfix: testing through proxy by making sure host name is set instead of ip, thanks to Fabrice Annic for the catch
- Bugfix: a regex/logic/if error in test_target, thanks Pavel Kankovsky for the bug report. 401/302 messages will now report regardless of test/pass fail.
- Bugfix: -dbcheck now identifies duplicates without relying on message text, thanks Jericho / Attrition.org for pointing this out
nikto.pl 1.12
- Rearranged order of get_banner & setup so that it would be called right
nikto_headers.plugin 1.08
- Added DAAP header check
nikto_core.plugin 1.18
- Fixed get_banner to properly handle multi host/port scans
nikto_outdated.plugin 1.12
- Fixed improper matching in version evals, reported by Paul Bakker
nikto_core.plugin 1.17
- Reordered loop code to make -f scans faster.
- Added a skip for "(Win32)" in the version updates back to cirt.net
nikto_outdated.plugin 1.11
- Stripping () from version strings
09.24.2003 Nikto 1.31 release
nikto_core.plugin 1.16
- Fixed a bug in resolve() that may prevent name lookups when host files used
- Fixed a bug in resolve() where scan would exit if 1 name resolution from host file failed
- Changed set_targets so that if the -h value exists as a file it reads that instead of resolving it as a name. This eliminates need for .csv or .txt file name endings.
- Added auto or semi-auto update of version strings to CIRT.net. This is done through a simple GET request. Controlled via config.txt's UPDATES variable.
*ABSOLUTELY NO* server info is sent... only versions from HTTP headers, i.e. "Apache/4.0". Thanks to Jericho for feedback/ideas.
- Added a host counter output at end & for every 10 hosts
- Set CHANGES.txt download only on *code* updates, not DBs
- Added MAX_WARN to config.txt for warning level on OK/Moved messages, thanks Jericho for the suggestion.
- Added PROMPTS to config.txt to allow user control of prompting--good for unattended scans
- Added a regex test to dbcheck() better catch errors in server_msgs.db
- Thanks again to Jericho for many updated tests/information.
- Cleaned up port scan code
- Fixed/improved scanning through proxies
nikto_outdated.plugin 1.09
- Added support for sending updates of version strings to CIRT.net. See nikto_core.plugin version 1.15 notes.
LW.pm - 1.8
- Updated to LW.pm v1.8, see the change log included with it (www.wiretrip.net/rfp/).
nikto.pl - 1.10
- Implemented versioning on nikto.pl (!), many changes to support core 1.15
- Put 'require LW.pm' down *after* we know where it is.. duh. Thanks J Barber (ussysadmin.com) for the suggestion. Also changed it 'require' vs 'use' so in the future I can update it, if necessary.
- Hosts are now tested in the same order as the appear in an input file
nikto_outdated.plugin 1.08
- Fixed nasty regex bug in the version eval, and made more efficient. Pointed out by fr0stman, thx Zeno for assistance
nikto_headers.plugin 1.07
- Added Host header back after delete in IIS Content-Location check. Thanks to Abdi Ponce for the bug report & debug.
nikto_httpoptions.plugin 1.04
- Changed PROPPATCH, TRACK, TRACE messages. Changed PROPFIND message, thanks to Jericho for tracking down some good info on it. Added SEARCH message.
nikto_core.plugin 1.14
- Added


text:
Published By : 10 Feb 2016 | Published By : QYRESEARCH
Given that they determine the flavor of any recipe and food preparation, spices and seasonings form crucial ingredients of any cuisine. Each cuisine has its own characteristic spices and seasonings, which lend the preparations their distinct tastes. In fact, the spices and seasonings market has played a major role in the history of humankind. Unfavorable environmental conditions in Europe led many countries within the region to set up outposts in Asia and began trading valuable items such as precious stones and gold for spices. Today, however, the tables seem to have been turned and cuisines of Western Europe seem to be gaining much popularity in Southeast Asia. This is anticipated to fuel the Asia spices and seasonings market in the near future.
Despite the economic turbulence in many countries around the world, the market has managed to sustain itself thanks to the significant role spices and seasonings play in one's daily diet. This growing demand for different cuisines in various parts of the globe is expected to push the global market to expand at a steady pace.
Asia Pacific to Continue Dominating the Global Market
Among the major seasonings and spices markets – Asia Pacific, North America, Europe, and Rest of the World – Asia Pacific holds the dominant share in the overall market, being the largest consumer as well as producer of spices in the world. The booming spice trade across the entire Southeast Asia region during the 17th and 18th centuries is a key factor for Asia Pacific's lead position. In terms of value, however, Asia Pacific comes in second, the first being Europe. European nations are largely dependent on spice imports, thereby accounting for a massive share in the high value trade transactions in the spice and seasonings market. The indigenous consumption of spices and seasonings in Asia Pacific is also a key growth driver.


text:
In the past week, I have had at least two men facing separate allegations of outraging the modesty of women approaching me for guidance on appointing suitable legal advisers.
This is unsurprising. I am hearing of more such cases. Perhaps, we are opening up too fast as a society, or becoming trigger-happy in expressing our feelings. Alternatively, it may be due to an incapacity to control one's rage or urge.
The men involved usually went to clubs to party. They met random women. A misunderstanding occurred. They were accused of molesting the women.
Those cases where one is charged and convicted form only a tip of the iceberg.
A lot of times, it is all a major miscommunication. The police are called in, but no investigation is initiated. Sometimes, an investigation by way of police questioning is triggered but no charges are pressed.
Then, there are those who are charged but a composition by way of settlement is mutually agreed to, and the cases are accordingly discharged. In one case many years ago, the woman expressly told the man to offer her a certain sum of money and she would, with the consent of the court, withdraw the case.
I am told such instances are not isolated, and women obviously know what their rights are in such situations.
However, this does not mean the man is free even though the court effectively acquits him. The record of the charge follows him for life.
It will come up in background checks. He will be deprived of certain jobs like joining the financial services sector or work in the protective services industry.
I am worried by this trend, that a man is black-marked for life for what is essentially a miscommunication or misunderstanding, or a lack of sensitivity in handling a member of the fairer sex.
My own sense is that we may have set the bar too low for a woman to claim she has been molested. If this is not the case, there may be a need to look at the process to enable some kind of "without prejudice" mediation or adjudication of the matter, particularly in cases where the circumstances do not justify a criminal record.
Dharmendra Yadav
Please consider the environment - do you really need to print this?
Do leave a comment as it will make a difference.


text:
Calprotectin (Macrophage Marker) Antibody - With BSA and Azide
Mouse Monoclonal Antibody [Clone CPT/1028 ]
|Primary Accession
|Other Accession
|6280, 112405
|Mouse / IgM, kappa
|Clone Names
|Calculated MW
|Gene ID
|Other Names
|Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100A9, CAGB, CFAG, MRP14
|Store at 2 to 8°C.Antibody is stable for 24 months.
|Calprotectin (Macrophage Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
|S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH- oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2/P67PHOX. The extracellular functions involve proinflammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF- kappa-B signaling pathways resulting in the amplification of the proinflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2+) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect; regulates cell survival via ITGAM/ITGB and TLR4 and a signaling mechanism involving MEK-ERK. Its role as an oxidant scavenger has a protective role in preventing exaggerated tissue damage by scavenging oxidants. Can act as a potent amplifier of inflammation in autoimmunity as well as in cancer development and tumor spread. Has transnitrosylase activity; in oxidatively-modified low- densitity lipoprotein (LDL(ox))-induced S-nitrosylation of GAPDH on 'Cys-247' proposed to transfer the NO moiety from NOS2/iNOS to GAPDH via its own S-nitrosylated Cys-3. The iNOS-S100A8/A9 transnitrosylase complex is proposed to also direct selective inflammatory stimulus-dependent S-nitrosylation of multiple targets such as ANXA5, EZR, MSN and VIM by recognizing a [IL]-x-C- x-x-[DE] motif.
|Cellular Location
|Secreted. Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein Note=Predominantly localized in the cytoplasm. Upon elevation of the intracellular calcium level, translocated from the cytoplasm to the cytoskeleton and the cell membrane. Upon neutrophil activation or endothelial adhesion of monocytes, is secreted via a microtubule-mediated, alternative pathway
|Tissue Location
|Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers
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Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain. Calprotectin comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. Calprotectin has antibacterial, antifungal, immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore calprotectin is also detectable in feces. Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.ĀThis MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and is important for identifying macrophages in tissue sections.
Cross, S.S., et al. 2005. Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11 are all overexpressed in common cancers. Histopathology 46: 256-269
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- Thank you commenters!
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Jelly in car
Small Plastic Toys Train Car With Candy Assorted Coconut JellyMater, power source is fruit jelly. One of the big 3, he likes all kinds of jellies, and when Carry has too much to delivery, he will come to help without any hesitation.Read More
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Assorted Fruit Jelly In THE PICK-UP TRUCKMini Fruit Jelly Cup with functional truck container
New models launched this year. Fruit jelly cup with assorted fruit flavors makes the jelly cups taste more delicious and attractive. Truck container with 3 different size are very collectable and meet different consumers requirement. If you looking for a gift for your kids, Just it!Read More
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Rightsizing Your Life with Simplicity
Rightsizing Your Life
Authentic – Intentional – You
If any of these scenarios resonate, rightsizing may be right for you.
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Moon Round Lounge Table
Moon lounge designed by Space Copenhagen for Gubi is a coffee table with top in black stained solid oak with a clear coat and stained oak base. The Moon Collection's design, that draws inspired by the moon, includes dining tables and lounge tables in different sizes.
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The projects Space Copenhagen has turned their hands to include everything from interior design, to furniture and refined objects for everyday use as well as artistic installations and art direction. Their furniture ideas are often initiated in relation to interior design in the hospitality and luxury retail sector – an area where the studio has established a strong identity. Space Copenhagen has done interior design for some of the world's most influential restaurants such as Nordic pioneer restaurant NOMA, Geranium, owned by Bóchuse D'or winner Rasmus Kofoed and newcomer Geist, run by Michelin star chef Bo Bech.Learn More
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text:
- Research article
- Open Access
- Open Peer Review
Hospitalized poisonings after renal transplantation in the United States
- Kevin C Abbott1Email author,
- Rebecca A Viola2 and
- Lawrence Y Agodoa3
© Abbott et al; licensee BioMed Central Ltd. 2002
- Received: 27 September 2002
- Accepted: 26 November 2002
- Published: 26 November 2002
The national incidence of and risk factors for hospitalized poisonings in renal transplant recipients has not been reported.
Historical cohort study of 39,628 renal transplant recipients in the United States Renal Data System between 1 July 1994 and 30 June 1998. Associations with time to hospitalizations for a primary diagnosis of poisonings (ICD-9 codes 960.x-989.x) within three years after renal transplant were assessed by Cox Regression.
The incidence of hospitalized poisonings was 2.3 patients per 1000 person years. The most frequent causes of poisonings were immunosuppressive agents (25.3%), analgesics/antipyretics (14.1%), psychotropic agents (10.0%), and insulin/antidiabetic agents (7.1%). In Cox Regression analysis, low body mass index (BMI, <21.6 vs. >28.3 kg/m2, adjusted hazard ratio (AHR), 3.02, 95% CI, 1.45–6.28, and allograft rejection, AHR 1.83, 95% CI, 1.15–2.89, were the only factors independently associated with hospitalized poisonings. Hospitalized poisonings were independently associated with increased mortality (AHR, 1.54, 95% CI 1.22–1.92, p = 0.002).
Hospitalized poisonings were associated with increased mortality after renal transplantation. However, almost all reported poisonings in renal transplant recipients were due to the use of prescribed medications. Allograft rejection and low BMI were the only independent risk factors for poisonings identified in this population.
- poisonings
- drug overdose
- medication error
- body mass index
- rejection
- diabetes
- complications
- pharmacist
Poisonings are among the most frequent indications for hospitalization in the United States [1]. However, the frequency of hospitalizations for poisonings (drug overdose or toxicity) in renal transplant recipients has been infrequently reported, [2, 3] in contrast to its occurrence in kidney donors [4, 5]. Because many medications used by transplant recipients can be toxic, it might be expected that renal transplant recipients would have a higher risk of poisonings than the general population, especially in the first post-transplant year when dosages of immunosuppressive medications are usually at their highest. Analysis of the incidence and causes of poisonings represents an opportunity to explore the frequency and risk factors for medical errors, since many such complications may be avoidable. The impact of hospitalized poisonings on subsequent survival after renal transplantation has also not been assessed. Therefore, we analyzed national diata from the USRDS report. Our objectives were to determine the risk factors for and mortality associated with hospitalized poisonings after renal transplantation.
Patient population
This study used data from the United States Renal Data System (USRDS), using standard analysis files (SAF's) as of May 2000. The variables included in the USRDS standard analysis files (SAF's), as well as data collection methods and validation studies, are listed at the USRDS website, under 'Researcher's Guide to the USRDS Database', Section E, 'Contents of all the SAF's', http://www.usrds.org and published in the USRDS. The demographics of the renal transplant population have been previously described (2001 USRDS report). SAF.TXUNOS was used as the primary dataset, and merged with variables from SAF.HOSP for hospitalization data, and SAF.PATIENTS for dates and causes of death as well as causes of renal disease, as previously reported [6–8]. Patient characteristics and treatment factors were those at the date of transplant. Recipients of organs other than kidneys were excluded.
Outcome definition
We conducted an historical cohort study of the incidence, risk factors and associated patient survival for hospitalized cases of poisonings (based on International Classification of Diseases-9th Modification Diagnosis Codes (ICD9) 960.x-989.x) as a primary discharge diagnosis in renal transplant recipients. Only the primary discharge diagnosis was used to ensure these were active diagnoses, ie, to exclude diagnoses with "history of poisonings." These diagnoses include potential overdoses for heroin, but not for cocaine or other illicit drugs. These diagnoses also include most known causes of environmental exposures, including minerals, pesticides, vaccinations, miscellaneous chemicals and certain foodstuffs. The first hospitalization for poisonings after the first renal transplant for a given individual occurring on or after 1 July 1994 and before 1 July 1998 (which could include a repeat transplant), with followup time truncated at three years was counted in analysis. Hospitalizations were chosen because they were more accessible in the database and less subject to interpretation than outpatient cases of poisonings, especially since the USRDS database has no information on confirmatory studies. Hospitalization data for transplant recipients may be unreliable after the patient has survived ≥ 3 years post transplant, when hospitalization reporting to Medicare for patients 65 years or younger is no longer required. However, Medicare reporting starts immediately after transplant, regardless of preceding dialysis status. All hospitalizations with a primary discharge diagnosis for poisonings were extracted from SAF.HOSP, merged with the transplant file, and hospitalizations outside the range of the study period were excluded. Hospitalizations for poisonings occurring at any time after renal transplant, including after graft failure (censored for patient death), were counted in analysis.
Variables used in analysis
The independent associations between patient factors and hospitalizations for poisonings were examined using multivariate analysis with stepwise Cox Regression (likelihood ratio method) including recipient and donor age, recipient race, gender, weight, pretransplant dialysis (yes/no), year of transplant, duration of dialysis prior to transplantation, total follow-up time, repeat transplant, donor cytomegalovirus serology, dialysis in the first week after transplant (delayed graft function, yes/no), rejection (diagnosis or treatment) occurring during the first six months after transplant, induction antibody therapy, maintenance immunosuppressive medications at time of discharge after transplant surgery, graft loss (analyzed as a time-dependent covariate as previously described), [9] and cause of ESRD (diabetes, systemic lupus erythematosus (because of the potential effect of corticosteroid therapy prior to renal transplantation), hypertension and glomerulonephritis). Episodes of rejection were not restricted to those occurring in the first year, in contrast to studies of allograft function, since there is no evidence that late (vs. early) rejection has a different impact on poisonings. The total cumulative dose of prednisone was not available in the USRDS. Both the USRDS and UNOS track the numbers of days of prednisone administered prior to initial hospital discharge, however values were missing for >90% of patients in both databases and could not be used as a covariate in the above analyses. Maintenance immunosuppressive medication use at the time of discharge after transplantation was also analyzed as a preexisting covariate. Information on use of medications (other than immunosuppressive medications), alcohol, tobacco, or radiologic procedures was not available.
Survival times
We defined patient survival times as the time from when patients had their first renal transplant during the study period to the time of death or most recent follow-up date (which was considered May 2000). For time to poisonings, survival time was defined as the time from first renal transplant until hospitalization for poisonings, with patients censored at death, loss to followup, or end of the study (which was considered 31 December 1999, since this was the most recent hospitalization date). The patient survival probabilities were estimated by using the Kaplan Meier method.
Statistical analysis
All analyses were performed using SPSS 9.0 TM (SPSS, Inc., Chicago, IL). Files were merged and converted to SPSS files using DBMS/Copy (Conceptual Software, Houston, TX). Univariate analysis was performed with Chi-square testing for categorical variables and Student's two-sided t-test for continuous variables. Variables with p < 0.05 in univariate analysis for a relationship with development of hospitalization for poisonings were entered into multivariate analysis as covariates. Kaplan-Meier analysis was used to construct survival plots of time to hospitalized poisonings after renal transplantation. Log-log plots were inspected to assess for proportionality of hazards over time. Stepwise Cox proportional hazards regression (likelihood ratio method) was used to model the association of patient factors with hospitalized poisonings. In order to control for misspecification errors, a random sample of 25% of patients was excluded from analysis and coefficients estimated for this sample. The sample was frozen, and coefficients estimated from the 25% sample. Because hospitalizations for poisonings were uncommon, Poisson Regression was used for validation, using the GENLOG approximation in SPSS. In order to estimate the association of hospitalizations with all-cause mortality, Cox-nonproportional hazards Regression was utilized. Times after hospitalization for poisonings were entered as 1, all other times were entered as 0, as previously described [10, 11]. Patients with missing information for variables were excluded from the multivariate models, resulting in models smaller than the total population. Hierarchically well-formed models were used for the assessment of interaction terms [11].
Most Frequent Diagnoses for Hospitalized poisonings after Renal Transplantation
ICD9 Code
53 (25.3)
24 (14.1)
14 (8.2)
Aromatic AnalgesicsA
6 (3.5)
4 (2.4)
1 (0.6)
Psychotropic Agents
17 (10.0)
10 (5.9)
6 (3.5)
1 (0.6)
12 (7.1)
4 (2.4)
15 (8.8)
5 (2.9)
2 (1.2)
2 (1.2)
Cox Regression Analysis of Factors Associated with Hospitalized Poisonings
P value
BMI <21.6 vs. >28.3 kg/m2
Rejection within 6 months after transplant
N in Final Model
The present study demonstrated that almost all hospitalizations for poisonings after renal transplantation were due to the use of prescription medications, even though ICD9 codes 960–989.x also include poisonings from environmental toxins, vaccines, and anesthetic agents. Because many immunosuppressive medications are toxic, this was not a surprising finding. However, reports from the medical literature have been infrequent, as indicated previously. In fact, a Medline search for the terms "medication error transplant" yielded only 14 papers, [12, 13] and none was returned for the search "medication error renal transplant." Therefore, review of the medical literature might give a misleading indication of the frequency of this complication. Although reported hospitalizations for poisonings as a primary diagnosis were not common, hospitalizations for poisonings were independently associated with increased mortality in renal transplant recipients, and also represented potentially avoidable morbidity with a mean length of stay of over 4 days.
Anti-neoplastic/immunosuppressive agents were the most common cause of poisonings in this population, as would be expected. The current study almost certainly underestimates the incidence of serious immunosuppressive drug toxicity in this population. In addition, renal transplant recipients have many potential indications for the use of analgesics/antipyretics, post-operative pain among them [14]. The frequent occurrence of poisonings due to analgesics after renal transplantation may therefore seem understandable. However, although the risk of poisonings was highest in the first few months after transplantation, the increase in relative risk in this time was not visually remarkable (Figure 1), and the risk of poisoning continued in a constant fashion after transplant. There was certainly no early peak followed by a dramatic stabilization in rates of poisonings, as has been demonstrated for hospitalizations for cytomegalovirus disease, [15] contrary to what might have been expected. This suggests the possibility that either the dosing or use of these medications may not be adjusted optimally after renal transplantation.
Benzodiazepines/tranquilizers were the third most common cause of poisonings in this study. It is noteworthy that calcineurin inhibitor toxicity may mimic anxiety or nervousness, [16] which are common indications for the use of benzodiazepines. In addition, many antidepressive agents may raise levels of calcineurin inhibitors [17]. Results of the present study raise the possibility that indications for treatment with benzodiazepines may actually represent toxicities of calcineurin antagonists, which might be best managed by adjusting the dose of the calcineurin inhibitors. Until then, we would suggest that the possibility of other drug toxicities, including drug interactions, be thoroughly excluded before prescribing benzodiazepines in this population. Often overlooked is the effect of erratic compliance with azole antifungals, anticonvulsants or other medications that inhibit or induce calcineurin inhibitors.
The high frequency of poisonings due to insulin/antidiabetic agents is also not surprising given the high frequency of diabetes among renal transplant recipients, although diabetes was not an independent risk factor for poisonings in the present analysis. This suggests that diabetic transplant recipients should be monitored with particularly close attention, perhaps in concert with regular visits with a pharmacist [18] or as part of a disease management program to reduce medical errors [19].
Considering that almost all causes of hospitalized poisonings after renal transplantation were attributed to prescription medications, the risk factors for hospitalized poisonings in the present study, namely allograft rejection and low body mass index, are all the more remarkable. The significance of a low body mass index as an independent risk factor for poisonings in this analysis as a risk factor for hospitalized poisonings, independent of age, suggests the possibility of suboptimal dose adjustment of medications. This particularly applies to calcineurin inhibitors, which are lipid soluble and have a large volume of distribution. Most calcineurin inhibitors are initiated adjusted for patient weight. However, in a small percentage of patients currently recommended doses may still result in toxicity. Area-under-the-curve monitoring gives an estimate of total drug exposure and may help minimize toxicity, particularly in patients with unusual clinical responses to standard dosing [20]. It would be useful to test this hypothesis in future studies.
The association of poisonings with allograft rejection in this category of patients may represent toxicity due to bolus intravenous or high dose oral corticosteroid therapy, or significant drug-drug interactions in this setting, which the database could not determine. However, the findings of the present analysis suggest a need for providers nationally to reevaluate the use of immunosuppressive agents in a systematic fashion after transplantation. The management of renal transplant patients is certainly not uniform; in some centers, the primary transplant surgeon may continue management of the patient up to a year or more after transplant, while in other centers a nephrologist or even primary care physician may assume primary management of the patient after the first transplant month. It is possible that more standardized guidance on dosing and the possibility of drug interactions would be beneficial. Currently, there are no clinical practice guidelines on the dosing of transplant related medications, although certain institutional guidelines do exist [21].
The present study is limited by use of primary hospitalization diagnoses for outcomes. The true frequency of poisonings and medication errors in the renal transplant population is most likely underestimated. Because of the study's retrospective nature, many other factors could not be validated. Patients with multiple potential causes for admission may not have been included among patients with hospitalized poisonings. However, the study is population based, and because accurate coding for hospitalization discharge is required, is likely to be less subject to reporting bias than case reports of poisonings in the medical literature.
The present study could not determine the reason for poisonings. In short, the possibilities of patient error vs. provider error could not be distinguished. However, consultation with pharmacists may reduce both [22]. Given the looming shortage of nephrologists, [23] nurses, and other medical providers, [24] multiple safeguards need to be established to minimize the possibility of error as much as possible in these complex and challenging patients. This is particularly true given the significant associations of both body mass index and allograft rejection with hospitalized poisonings in this analysis, which may indicate that more complex and individualized methods of medication dosing may be necessary after renal transplantation than are currently used. The present study identifies specific targets for investigation and improvement.
Authors' Affiliations
- [http://www.cdc.gov/nchs]
- Chang SH, Lim CS, Low TS, Chong HT, Tan SY: Cyclosporine-associated encephalopathy: a case report and literature review. Transplant Proc. 2001, 33: 3700-1. 10.1016/S0041-1345(01)02510-6.View ArticlePubMedGoogle Scholar
- Wong EH, Chan NN, Sze KH, Or KH: Serotonin syndrome in a renal transplant patient. J R Soc Med. 2002, 95: 304-5. 10.1258/jrsm.95.6.304.View ArticlePubMedPubMed CentralGoogle Scholar
- Chari RS, Hemming AW, Cattral M: Successful kidney pancreas transplantation from donor with methanol intoxication. Transplantation. 1998, 66: 674-5. 10.1097/00007890-199809150-00025.View ArticlePubMedGoogle Scholar
- Ravishankar DK, Kashi SH, Lam FT: Organ transplantation from donor who died of cyanide poisoning: a case report. Clin Transplant. 1998, 12: 142-3.PubMedGoogle Scholar
- Abbott KC, Duran M, Hypolite I, et al: Hospitalizations for bacterial endocarditis after renal transplantation in the United States. J Nephrol. 2001, 14: 353-60.PubMedGoogle Scholar
- Tveit DP, Hypolite I, Bucci J, et al: Risk factors for hospitalizations resulting from pulmonary embolism after renal transplantation in the United States. J Nephrol. 2001, 14: 361-8.PubMedGoogle Scholar
- Abbott KC, Hypolite IO, Hshieh P, et al: Hospitalized congestive heart failure after renal transplantation in the United States. Ann Epidemiol. 2002, 12: 115-22. 10.1016/S1047-2797(01)00272-1.View ArticlePubMedGoogle Scholar
- Abbott KC, Bucci JR, Cruess D, Taylor AJ, Agodoa LY: Graft loss and acute coronary syndromes after renal transplantation in the United States. J Am Soc Nephrol. 2002, 13: 2560-9.View ArticlePubMedGoogle Scholar
- Hypolite IO, Bucci J, Hshieh P, Cruess D, Agodoa LY, Yuan CM, Taylor AJ, Abbott KC: Acute coronary syndromes after renal transplantation in patients with end-stage renal disease resulting from diabetes. Am J Transplant. 2002, 2: 274-81. 10.1034/j.1600-6143.2002.20313.x.View ArticlePubMedGoogle Scholar
- David Kleinbaum: Survival Analysis :. A Self-Learning Text (Statistics in the Health Sciences). Springer Verlag; New York, New York, May 1996Google Scholar
- Kruger HU, Bross-Bach U, Proksch B, Schmidt H, Dopfer R, Ehninger G: A case of accidental cyclosporin overdose with pharmacokinetic analysis. Bone Marrow Transplant. 1988, 3: 167-9.PubMedGoogle Scholar
- Yeh CN, Hsieh CH, Hung CM, Jeng LB, Chao TC, Chen MF: Acute overdoses of tacrolimus (FK 506). Dig Dis Sci. 1999, 44: 1650-2. 10.1023/A:1026635615532.View ArticlePubMedGoogle Scholar
- Dines CM: Improving renal transplant pain management. Hosp Case Manag. 1999, 7: 105-7.PubMedGoogle Scholar
- Abbott K, Hypolite I, Viola R, Poropatich R, Hshieh P, Cruess D, Hawkes C, Agodoa L: Hospitalizations for cytomegalovirus disease after renal transplantation in the United States. Ann Epidemiol. 2002, 12: 402-10.1016/S1047-2797(01)00283-6.View ArticlePubMedGoogle Scholar
- Bechstein WO: Neurotoxicity of calcineurin inhibitors: impact and clinical management. Transpl Int. 2000, 13: 313-26. 10.1007/s001470050708.View ArticlePubMedGoogle Scholar
- Vella JP, Sayegh MH: Interactions between cyclosporine and newer antidepressant medications. Am J Kidney Dis. 1998, 31: 320-3.View ArticlePubMedGoogle Scholar
- Matzke GR, St Peter WL, Comstock TJ, Foote EF: Nephrology pharmaceutical care preceptorship: a programmatic and clinical outcomes assessment. Ann Pharmacother. 2000, 34: 593-9. 10.1345/aph.19245.View ArticlePubMedGoogle Scholar
- Kliger AS, Diamond LH: Patient safety in end-stage renal disease: How do we create a safe environment?. Adv Ren Replace Ther. 2001, 8: 131-7. 10.1053/jarr.2001.23991.View ArticlePubMedGoogle Scholar
- Wong KM, Shek CC, Chau KF, Li CS: Abbreviated Tacrolimus Area-Under-the-Curve Monitoring for Renal Transplant Recipients. Am J Kidney Dis. 2000, 35 (4): 660-666.View ArticlePubMedGoogle Scholar
- 8/27/2002, [http://www.wramc.amedd.army.mil/departments/Medicine/Nephrology/sop/txp/txpmedprotocol.cfm]
- Chisholm MA, Mulloy LL, Jagadeesan M, DiPiro JT: Impact of clinical pharmacy services on renal transplant patients' compliance with immunosuppressive medications. Clin Transplant. 2001, 15: 330-6. 10.1034/j.1399-0012.2001.150505.x.View ArticlePubMedGoogle Scholar
- Estimating workforce and training requirements for nephrologists through the year 2010. Ad Hoc Committee on Nephrology Manpower Needs. J Am Soc Nephrol. 1997, 8: S9-13. i–xxii, 1–32 passimGoogle Scholar
- Bond MA: Health promotion and disease prevention in kidney transplant recipients. J Transpl Coord. 1998, 8: 221-4.View ArticlePubMedGoogle Scholar
- The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2369/3/10/prepub
Pre-publication history
This article is published under license to BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.


text:
Frequently Asked Questions:
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A: Nikon D60 camera with a Nikkor 35mm 1:1 lens.
Q: Do you have a 'Day Job'?
A: Not since 2010. I work as a fulltime freelance illustrator from my home studio.
I live off of my sales on Etsy plus my other online shops, as well as custom commissioned projects, wholesale orders and other freelance work.
Q: What kind of computer do you use?
A: I have a 27" iMac and a 11" MacBook Air for travel (aka sitting on the sofa). I also use a Wacom Bamboo tablet for digital drawing etc.
Q: Do you trace?
A: Nope I don't. I like my drawings a bit wonky and imperfect. Gives them character ;)
Q: How are your illustrations created?
A: All illustrations are drawn for hand by me on paper with pen. I then scan these drawing and add digital colors in Photoshop... this way they keep their hand drawn quality but can still be mass produced easily. All prints are professionally printed at a local printshop in Stockholm.
Q: What software do you use?
A: For the most part the majority of my work is created/colored in Photoshop, but I also create vector images in Illustrator. On certain projects I only use Illustrator to just perfect my outlines (such as when creating my silk scarf/textile designs). I then usually choose to color in Photoshop.
Q: May I interview you for my blog or magazine?
A: Yes please! I would love that. Contact me here... email@example.com
Q: May I blog about your work and use your EmmaKisstina images for my post?
A: Yes of course! But please link back to my website www.emmakisstina.com or any of my other sites or shop. Oh and please do get in touch, I'd love to read your post, and share.
Q: Would you be interested in doing a Giveaway or promotion with me on my blog?
A: I love collaborating with bloggers! Please contact me to introduce yourself and your blog. Then we'll see if we can work something fun out.
Q: I'd love to be a part of your Blogger What's in my Bag illustrated series?
A: I've gotten many requests from bloggers to be a part of my series. Although I have a very long waiting list, I'd love for you to get in touch. Otherwise you can commission a custom illustration in my Etsy shop.
Q: Where are your Silk Scarves produced?
A: They are both printed and sewn in England, United Kingdom.
Q: Do you have any tips or advice for someone who also wants to go into freelancing?
A: I've started a 'Take my own Advice' column about working in the freelance business on my blog.
Read my posts here...
Q: Do you offer discounts?
A: Of course, on occasion! Like my EmmaKisstina Facebook page to say up to date with
promotions/giveaways offered at the moment.
Q: Are your prints environmentally friendly?
A: I try my best. All prints are printed locally in Stockholm, Sweden. I always take public transportation to pick them up. I also use recyclable packaging, and make sure to recycle all paper scraps.
Q: Do you work with international customers? Do you ship Worldwide?
A: I happily work with anyone from any country and of course ship all over the world.
Q: What is SEK?
A: SEK is Sweden's currency, Swedish Kronor. All of my prices in my Etsy shop are in SEK. Please use Etsy's automatic currency converter (find it in the footer) to change prices into your currency.
Q: What is your return policy?
A: I have the policy of No Returns. All sales are final. But please don't hesitate to ask if you are unsatisfied by your order in any way.
Q: How long do wholesale orders take to process and ship?
A: All of my prints and posters are printed to order at my local printshop. My printshop takes approx. 1-3 days to print large orders. International shipping takes about 5-10 days. For information about my other products please contact me.
Q: Do you have freelance project price list?
A: No. I price each project individually.
Q: What are your shipping policies?
A: I ship my packages via regular wonderful first class priority Swedish Royal mail. Usually takes about 1-2 days to ship within Sweden, 2-4 days to ship within Europe, and about 5-10 days to ship to the United States and the rest of the world from Sweden.
NO tracking available on my packages. If you are interested in tracking or express, these services can be added for an extra fee. 95:- SEK extra on top of other shipping charges.
I do my best to package my prints with care. Small - Large prints are packaged in plastic sleeves and sent in cardboard photo mailers. Posters are rolled in tissue and sent in cardboard tubes. All include sweet handwritten thank you notes.
All packages are shipped out up to 4 weekdays after payment is received. I really try my best to get them ready as soon as I can. All prints are professionally printed at my local printshop here in Stockholm to order, therefore delays can occur if my printshop is super busy.


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Since the early 1990s, there has been a remarkable export boom of natural resource- based products from Chile, including wine, farmed salmon, forestry and wood products. This phenomenon is surprising, considering the monopolistic role played by advanced countries in these industries (e.g. Italy, France and Spain in the wine industry; Norway, Scotland and Canada in the salmon industry). It also raises questions on whether the conditions under which it is taking place are any different from those that in the past led to the repeated failures of a development model based mostly on the exports of natural resources. From a traditional sector totally oriented to the domestic market and in deep crisis due to political and economic instability, the Chilean wine industry has gained international recognition since the early 1990s. It has become a large export-oriented industry -over 60 percent of the production is currently exported- together with other non-traditional industries such as salmon. Chile has been gradually identified by international consumers as an ideal country for producing modern varietal (fresh and fruity), good-value-for-money wines, and it has won worldwide recognition in the wine community faster than any other country in modern history (Phillips, 2000). This is a striking achievement, considering that until the 1970s Chilean wines were confined to the niche of decent-but-not-great wines, based on few varieties cultivated and the relative homo- geneity of their taste. This paper analyses whether and how, under the globalizing trends that began in the last quarter of the twentieth century, Chile was able to transform some of its primary commodities such as wine into high-quality, diversified, processed goods, with increasing value-added content and export price per unit, thus becoming a platform for development. In particular, as a complement to previous studies, this paper looks specifically at the role of knowledge intensive services in the Chilean wine sector. It is based on the hypothesis is that these services have allowed Chilean wineries to add value to their wine exports and constantly improve their operations along the different stages of the value chain. This paper is structured as follows. Section 2 describes Chile's remarkable wine export performance and reviews previous studies regarding the main factors that explain this expansion. Section 3 provides a description of the five main segments of the wine value chain and the multiple service inputs within each one of them. The motivations to produce these services in-house or subcontract are discussed in section 4. The results of a survey, carried out in the context of this study, to assess which services are produced in-house or outsourced are discussed in section 5. The last section concludes and provides suggestions for future research.
This article was written by Karl Storchmann


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Australia-based Gabriel Scanu learned to use a DSLR at the age of 12, taught by his cinematographer father. Now just 20, Scanu has also learned to use a drone and has mastered Lightroom presets, and the results are stunning:
Scanu dropped out of school to pursue shooting full-time. On his Instagram page he plugs the custom Lightroom presets he sells for $39, and I have never not minded being advertised to so much!
There's an in-depth interview with Scanu where he goes into detail about his equipment and such here.
Which one is Gabriel? Is he the one in blue?
Just because your prototype is finished, doesn't mean your work is. Here industrial designer Eric Strebel points out the importance of having a pre-established, ready-to-go camera set-up, as with deadlines you may need to ship your prototype out the day it's finished, and you want a way to document your
Are you the type of designer who wants to know how your tools work, or are you only concerned with the utility they provide? If you're the former, you're bound to find the following video interesting. TechQuickie breaks down the difference between JPEGs, PNGs, GIFs, TIFFs, SVGs and Raw files,
While recently lauding/lamenting Cotopaxi's rare stylish travel backpack, I was struck by how few options there are for slick packs that accommodate bulky cameras and travel necessities without losing EDC appeal. Options for sturdy carry alls tend towards sack-like hiking packs, dorky extra-padded equipment bags, or going Full Messenger with
Once cameras were added to cell phones, society's documentation of everything grew explosively. But there are several earlier generations of images—shot by our parents, our grandparents—that we do not have practical access to, because they are trapped on old film negatives that we're never going to bother bringing to a
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The latest adventure in DreamWorks' popular 'Shrek' series is short but sweet, and delivers a half-hour of fun family entertainment.
Anyway . . . when I sat down Wednesday night, November 28, to view the new holiday special Shrek the Halls, I was thinking what most viewers were probably thinking: "ANOTHER Shrek sequel?!" However, Shrek the Halls is only a 30-minute special and not a full-blown 90-minute sequel.
The special takes place after Shrek the Third, when Fiona and Shrek are preparing for their first Christmas with their new baby triplet ogres. As it turns out, Shrek hasn't ever celebrated Christmas before and doesn't exactly know what all the hubbub is about. When he attempts to please Fiona by throwing a Christmas party, mayhem breaks loose when his friends each tell their own version of "The Night Before Christmas." Eventually Shrek becomes aggravated with his friends for ruining his first Christmas, only to discover that being with the ones you love during the holidays is part of what makes Christmas so special.
Shrek the Halls had the potential to be cheesy and sequel-ish, but fortunately it doesn't overdo anything and gives each of the favorite characters their own bit of airtime. And, like every Shrek installment so far, Gingy steals the show. Like most Christmas specials, this one isn't spiritual, though at one point when Shrek asks what the true meaning of Christmas is, I half-expected somebody to pull a Linus. They didn't, though.
Although it's not yet available for sale on DVD, you can probably bet it will be come next November. So, if you can, try to catch Shrek the Halls when it airs Tuesday, December 11, 2008 at 8:00pm on ABC. That's the only airtime that's currently scheduled for the special and you sure wouldn't want to miss it.


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The queen butterfly is a member of the nymphalidae family and resembles its cousin the monarch butterfly. It's called a milkweed butterfly because the caterpillar feeds on milkweed. The adults sip nectar from the milkweed flowers. The queen is an orange-brown butterfly whose wings have black borders and forewings have white spots. The black veining is more prominent on the hindwings. The average wingspan is about 3 inches.
The queen can be found from Brazil to Florida and in the American southwest. It prefers sunny, open areas like roadsides, pastures, meadows and fields. It also prefers a warm climate and doesn't migrate quite as extensively as the larger monarch butterfly.
The queen female tends to be larger than the male. During the complex courtship, the male uses organs called hair pencils to release pheromones to attract the females. After mating, the female lays one egg at a time on the milkweed plant. This may be because queen caterpillars are cannibalistic. The egg is oval, ribbed and ridged, with a flattened top and bottom. The caterpillar that emerges is blue-gray, with black, white, yellow, green and blue stripes and false tentacles. Its pupa is pale green and stippled with golden spots.


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Candidate's Reading Lists
I know our left-of-center readers will probably jump all over me for posting this, but I found this a rather interesting tidbit from an otherwise mundane interview of VP candidate Governor Sarah Palin.
What are you reading now?
SARAH: I am reading, heh-heh, a lot of briefing papers.
What about for fun?
SARAH: Do we consider The Looming Tower something just for fun? That's what I have been reading on the airplane. It's about 9/11. If I am going to read something, for the most part, it's something beneficial.
Well I am sure the troofers are sad that she isn't reading Debunking 9/11 Debunking, but I certainly can't fault her taste in books.
Labels: Sarah Palin, The Looming Tower


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The Brewer's Pantry One Gallon Dry Irish Stout makes a great, dry Irish stout. The dark roasted grains contribute a dry bitter and roasty flavour to this stout. Rich body with a smooth mouthfeel.
Each One Gallon Brew comes with all fresh ingredients necessary, a grain steeping bag, and complete instructions. Makes approximately 10-12 beers.


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Applying for a scholarship? Check out our scholarship essays database>
Sample cover letter for Full Time position at atk
I interested in the Marketing Consultant intern position for Circuit and Packaging Materials at DuPont. My work experience at Caterpillar as along with the knowledge that I have acquired through project and classes at Chicago-Booth gives me confidence that I can bring value to DuPont. I would like to focus on a few key characteristics of my experience that I believe can be leveraged as a Marketing Consultant Intern.
Experience developing pricing strategies: I worked with a local business to develop a market entry and pricing strategy for a new product. The market was segmented and highly competitive, so in order to achieve maximum profitability it was necessary to price discriminate. Looking at the segment with the highest profit potential and by understanding the voice of the customer, I was able to identify a bundled strategy that would satisfy both the company I was consulting for as well as the target customers.
Familiarity with Electrical Circuitry: A portion of my role at Caterpillar is to react immediately when an electrical failure is causing a stop in production. Although the assembly workers are able to diagnose a majority of issues, when they encounter a failure that is extremely difficult they will call me to identify root cause and fix the issue. Although I am not an electrical engineer, my electrical knowledge will be of significant value when working with the The Pyralux® and Interra® product families.
Created Model Excel VBA: I have a wealth of experience building models and tools using VBA. I recently created a tool that could extract data regarding product orders and attachments through the click of a button. This tool has automated what used to be learned through word-of-mouth and has transformed the entire process. Not only has this tool streamlined the information, but after it was implemented it reduced the failures due to incorrect software configurations by 100%.
I will arrive at DuPont with these skills already developed, allowing me to focus on the specific deliverables in this new role. You can see from my resume that I thrive on the opportunity to learn new things, this position will be the perfect combination responsibilities that both allow me to grow and also leverage my experiences. My enclosed resume will give you a better understanding of my background and skills.
Thank you for your consideration and I look forward to hearing from you.
See our template for making your own punchy cover letter


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TRPA Newsletter Spring 2019 (PDF)
San Marcos River Cleanup - March 2, 2019
TRPA Newsletter Spring 2018 (PDF)
FINAL JUDGMENT and AGREED PERMANENT INJUNCTIVE RELIEF
New Rules for Tubers on the San Marcos
Guadalupe Bass Restoration on Blanco After Smallmouth Invasion
TRPA Newsletter Spring 2016 (PDF)
TRPA Newsletter Fall 2015 (PDF)
A Linear State Park - An Alternative to WORD (PDF)
A Linear State Park - Slideshow (PDF)
ALERT! We CAN BAN Litter in Texas Rivers!
ALERT 4/16/2015: A Kinder, Simpler WORD (PDF)
ALERT 4/16/2015: Tubers Private Plan (PDF)
Devils River Working Group, 2014 Update
San Marcos River Shepherd Photos and Videos
Castroville WWTP Settlement Announced
Support Texas Bottle Bill 2013 - Keep Trash Out of Texas Rivers
Upper Neches Wild & Scenic River Study Act
VIDEO: The Neches - A Natural & Historic Treasure in Our Own Backyard
Scull's Crossing and Martindale Access (San Marcos River)
A 'Partial Victory' for Texas Streams
TRPA Takes a Stand on NBOL & Supports Guad River Road Alliance
The members of the Texas Rivers Protection Association are concerned about the quality of our remaining natural rivers and we invite you to join in our efforts...
Several years ago, a coalition of Texas conservation and recreation groups began to work to protect the diverse natural rivers of Texas. These groups continue to work together to protect our Texas Rivers.
During these efforts, Texas rivers have gained a broad and diverse band of supporters. In 1989, the coalition decided the time had arrived to incorporate formally and apply for non-profit, 501(c)4 status. In 2004, a conversion to 501(c)3 tax deductible status was granted. In 2001, TRPA acquired acreage and access easements at historic Hidalgo Falls on the Brazos River near Navasota. Memberships are available for both groups and individuals. TRPA leadership is made up of pro-river activists from across the state representing landowner coalitions, conservationists, canoe clubs, and fishing associations.
A whole river is mountain country and hill country and flat country and swamp and delta country, is rock bottom and sand bottom and weed bottom and mud bottom, is blue, green, red, clear, brown, wide, narrow, fast, slow, clean, and filthy water, is all the kinds of trees and grasses and all the breeds of animals and birds and man that pertain and have ever pertained to its changing shores...
John Graves
Web Design by rivergeek


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Dallas Man, Who Pleaded Guilty To Role In Cocaine Distribution Conspiracy Linked To Los Zetas Cartel, Is Sentenced To 84 Months In Federal Prison
DALLAS — Omar Guerrero Acosta, aka "Pilas," 30, of Dallas, was sentenced late last week by U.S. District Judge Jorge A. Solis to 84 months in federal prison, following his guilty plea in February 2013 to one count of conspiracy to distribute five kilograms or more of cocaine. He was also ordered to forfeit a vehicle, approximately $209,493 in cash and jewelry that had been seized. Today's announcement was made by U.S. Attorney Sarah R. Saldaña of the Northern District of Texas.
Acosta is one of 13 defendants indicted in September 2011 for running a cocaine distribution conspiracy in the Dallas-Fort Worth area that was linked to the Los Zetas cartel. Acosta is the tenth and last defendant convicted in the case to be sentenced; two defendants remain fugitives and charges against another were dismissed. Convicted defendants and their sentences are:
Cesar Alonzo De La Rosa Jordan, aka "Gordo," 30, 78 months
Rosendo Chappa, Jr., aka "Borado," 39, 87 months
Joel Alejandro Rodriguez, aka "Joe," 51, 98 months
Arturo Picaso, aka "Flaco," 32, 152 months
Ricardo Morales, Sr., 52, 70 months
Ricardo Morales, Jr., aka "Rica," 27, 3 years' probation
Jose Luis Rodriguez, aka "Mas," 41, 37 months
William Savala, aka "Will," 39, 51 months
Reynaldo Facundo, 32, 63 months
Acosta admitted that beginning in January 2011, cocaine supply sources in Mexico began importing multi-kilogram shipments of cocaine into the U.S. through border checkpoints near Laredo. Acosta admitted that couriers hired by the drug suppliers in Mexico delivered the cocaine to him and once the drugs arrived in Dallas, he and others maintained care, custody and control of the drugs at "stash" locations throughout the Dallas area. The total amount of cocaine that was reasonable foreseeable to him during the time of the conspiracy was more than 100 kilograms.
In July 2011, for example, Acosta's supply source delivered approximately 119 kilograms of cocaine to him and, subsequently, multi-kilogram quantities were distributed to multiple customers, including co-defendant Rosendo Chappa, aka ""Borado." Acosta admitted that on August 19, 2011, he and Chappa made arrangements for Chappa to deliver cash to Acosta in payment for seven kilograms of cocaine that Acosta had previously delivered to Chappa. On August 19, 2011, Acosta met Chappa at a department store parking garage in Dallas and collected approximately $159,000 in drug proceeds. Both Acosta and Chappa were arrested. After Acosta was arrested, law enforcement searched an apartment on Noel Road that he used, and they seized approximately six kilograms of cocaine and an additional $48,000 in drug proceeds that belonged to Acosta.
The FBI began its investigation into this large-scale drug trafficking organization, the Morales-Picaso Drug Trafficking Operation (MPDTO), as a result of intelligence gathered from the "Operation Greedy Grove" investigation and prosecution which targeted a large-scale cocaine, crack cocaine and marijuana distribution organization known for its violence. Operation Greedy Grove culminated in September 2010 with the arrest of 28 individuals on federal and state drug charges. Law enforcement officers seized approximately three kilograms of cocaine, 14 firearms and $210,000 in U.S. Currency and assets. The 16 defendants charged federally in that case have all pleaded guilty to their respective roles in the conspiracy have been sentenced, including defendant Gary Montgomery, who shot a Bureau of Alcohol, Tobacco, Firearms and Explosives agent during his arrest. Montgomery was sentenced to 348 months in federal prison.
The investigation revealed that the MPDTO was involved in the illegal importation of approximately 100 kilos per month from Mexico. Once the cocaine was smuggled across the border, the loads were distributed to members of the MPDTO in exchange for large sums of cash, which were then vacuum-sealed in bags, concealed in vehicles and transported back to Mexico. During the course of this investigation, law enforcement seized more than 36 kilograms of cocaine, seven firearms, 14 vehicles and nearly $300,000 cash, which was forfeited to the U.S.
This Organized Crime Drug Enforcement Task Force (OCDETF) investigation was conducted by the FBI and the Dallas Police Department. Assistant U.S. Attorney Rick Calvert was in charge of the prosecutions and Assistant U.S. Attorney John de la Garza handled the forfeitures.


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DFI shows BIOScure tech allowing remote BIOS flash
Computex Taipei 2009: Another company we managed to stop by today out in Nangang was DFI who was showcasing its full line-up of new motherboards.
The most interesting for us was its P55 board which features a new patent DFI technology called BIOScure. This new tech by DFI allows users to rescue a motherboard that either had a bad BIOS flash or a failed BIOS due to many reasons.
What it allows you to do is flash the BIOS of the bad motherboard from another computer via USB. The amazing thing is that the bad mobo doesn't even need to have power hooked up for it to work. DFI will end up bundling a Windows application that enables the magic to happen.
Jerry, one of key engineers of DFI was kind enough to introduce the technology to us below on video.
You can always rely on DFI to come out with some weird and wacky new technology, but most of the time they are usually quite good and very unique.


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artwork by Valentina Belloni
A little girl takes flight with a mythical unicorn against an enchanted sky.
Mouse + Magpie art prints, framed prints and canvas prints set the stage for little imaginations to run wild with big, bold colors and textures that establish the room's story and theme.
The quality of the print I received was very high quality. The illustrator's design pops right off the surface.
Become a Mouse + Magpie insider and get exclusive offers, details on new product launches and updates from our independent artist community!


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Tuesday, June 14, 2011
Witchlette : testing the costume
This is the first test fitting of the fabrics I have chosen for the Witchlette. Most are vintage fabrics that I have collected from various sources throughout the years. I fell that this is a good mix of colors and textures to give the old hag a real-world appearance. At this stage I like to let everything sink in for a few days, observe her in different lighting and take note of any changes or additions that need to take place before attaching her wardrobe permanently.
For instance, as much as I would like to press onward, the painting on the cauldron needs to be finished before any fabrics are applied. The plastic hands stand out as a beacon of laziness at this point, prompting me to push my comfort zone a bit to make them blend in with the rest of the piece. The forearms need some work as well since the fresh clean burlap glows like a beacon. Accessories, knickknacks and other bits and bobs will be the final touch to give her an authentic presence.
Overall I am pleased with the way this is turning out.
6 comments:
Lots of little, tiny details & finishing touches still to go, but it will add up to a great end product. Looking forward to seeing her completed.ReplyDelete
Hate when I have to wait on one aspect of a piece when all I want to do is jump ahead to something else.
Dave - its looking awesome so far! I will agree about the hands. Hands can be a bugger to sculpt, especially if you don't have dainty little fingers in the first place.ReplyDelete
A suggestion? I would take the hands you have already and put paper clay/air dry clay over the top. You already have your positions for them so it should be easier than starting from scratch.
Good idea Kim. I actually have started something very similar to what you suggested on the hands..they will be much improved.ReplyDelete
Wow, I think it is perfect just the way it is....when will it be for sale? :DReplyDelete
Fantastic piece as always!!
Thanks FQ. Just wait until you see the finished thing....ReplyDelete
I'm really looking forward to the new photos that feature all the movement forward from this last set. This is one of those pieces that pushes that invisible bar higher and higher - both in concept and execution.ReplyDelete
We should all be inspired to hotwire our creations for creepy leering and hungry reaching.


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O-T-G for 28 yrs. w/solar, wind & hydro
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Design & Consulting R.E., efficiency, green building, installation and training. Currently about 25% of my work is in the tourism sector, remote lodges around the world. The rest is 50% CA on grid commercial and 25% international.
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New Partner and Location for Idea Kraft
We are super excited to announce the addition of a new partner here at Idea Kraft – Chris Olsen!
Chris will be helping to expand Idea Kraft by adding digital marketing services such as social media advertising, search engine optimization and lead generation. Chris will also be opening and managing a new location for Idea Kraft in New Orleans, LA!
Chris comes to Idea Kraft with an extensive background in digital marketing for local, high growth, and startup companies. He attended Binghamton University and subsequently started a Binghamton based digital advertising agency, where he spent three years working with many of the area's largest businesses. Later, he served as Marketing Director at a high growth technology company before focusing on multiple startup ventures.
Idea Kraft NOLA will be located in Uptown New Orleans and will provide branding, web design and development, and digital marketing services to the many new startup, restaurant and entertainment businesses in the New Orleans area.
Lots more to come on all of these big things!


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Healthcare Resource Providers focuses on providing meaningful, data-driven recommendations designed to achieve results. Our scope of services ranges from project-based analysis to ongoing support of physician leaders and new managers. We normally maintain one long-term management contract to ensure our knowledge remains current and our ideas can be tested in a real working environment. The business environment for radiology is rapidly changing, highly demanding and unforgiving.
Our subject matter expertise is the result of hands-on management as well as work with numerous practices, billing companies, imaging centers and hospitals on a project basis. We have also been engaged by several leading software developers to develop marketing resources, analyze system workflow and advise on compliance issues.
Our leaders are hands-on professionals, supported by a select group of experienced front line billing/collections specialists.
Patricia (Pat) Kroken, FACMPE, CRA is a veteran radiology practice administrator with experience in process improvement, billing/collections, strategic planning, development of strong group/hospital working relationships, business development and compliance issues. As a long-time member of a physician/administrator team, she has a practical knowledge of the perspective and concerns of the radiologist.
Pat maintains an active and ongoing commitment to her profession as an author and speaker. Her approximately 200 articles have been published in leading industry publications and she has written for the Radiology Business Management Association (RBMA) Bulletin for more than 20 years.
Pat is a Past President of the RBMA, a Fellow in the American College of Medical Practice Executives (ACMPE), a Certified Radiology Administrator (CRA) and a Fellow of the Radiology Business Management Association.
For a copy of Pat's résumé click here.
Jennifer Kroken, MBA specializes in billing operations and has more than 20 years of experience in virtually all aspects of radiology billing. As a consultant, her focus involves the analysis of billing/collections, process improvement design and on-site troubleshooting when things just aren't going well (especially after a computer conversion). Jennifer has worked on several leading software platforms and brings a practical perspective to her consulting approach. She is well-known for her hands-on guidance to billing staff members, her ability to establish a trusted working relationship with them and therefore, her ability to quickly drive results.
Jennifer is on the Board of Directors of the RBMA, has served as a columnist for the RBMA Bulletin and formerly chaired the Editorial Advisory Committee for that organization. She has also been a speaker for several national meetings and contributes articles to national radiology publications.
For a copy of Jennifer's résumé click here.


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Watch Star Screen Awards 10 January 2016 Star Plus Winners Nominations Performances Live HD Video: The Screen Awards 2016 held in Mumbai was filled with Bollywood stars including Sonakshi Sinha, Ranveer Singh, Deepika Padukone, Rekha, Sonam Kapoor and the Bachchans.
Watch Star Screen Awards 10 January 2016 Star Plus Winners Nominations Performances Live HD Video
The award for the Best Actor in the female group went for her stunning performance in Piku to Deepika. He was won the best actor award, which he shared by Ranveer Singh's leading performance in Bajirao Mastani. While Kalki got the award in the female group for Margarita Irrfan Khan won the Best Actor in Talvar the jury's choice award.
Deepika Padukone additionally taken the prize for her Bajirao Mastani co star Priyanka Chopra, while Karan Johar taken the award of benefit of dear pal, SRK. Bajrangi Bhaijaan got the Best Picture – Popular Pick award.
Star Screen Awards 2016 Winners
Best Actor (male) – Ranveer Singh (Bajirao Mastani) and Amitabh Bachchan (Piku)
Best Actress (female) – Deepika Padukone (Piku)
Best supporting actor – Priyanka Chopra (Bajirao Mastani)
Popular choice male – Shah Rukh Khan (Dilwale)
Popular choice female – Deepika Padukone (Bajirao mastani)
Jury Choice Best Actor (Male) – Irrfan Khan
Jury Choice Best Actor (Female) – Kalki Koechlin
Best Film (Popular Choice) – Bajrangi Bhaijaan
Best film (Jury Choice) – Talvar
Best MALE Playback Singer – Papon
Best director: Kabir Khan
Best story – Bajrangi Bhaijaan
Best female Playback singer – Monali Thakur
Best Dialogue – Piku
Lifetime Achievement Award – Rishi Kapoor
Best special effects – Bajirao Mastani
Hope you enjoyed this article and gained information about Watch Star Screen Awards 10 January 2016 Star Plus Winners Nominations Performances Live HD Video. For more details stay connected with us. Also, you can put your queries in Comment Box, we will respond quickly.Don't forget to share this article with your near dears on social media sites such as Facebook, twitter, tumblr, pinterest, digg, google plus, linkedin, stumbleupon, etc. Be Happy