text:
rise and shine world
It was early morning when Monette literally pulled me out of the bed. We need to rush to Srah Srang in time for the break of dawn to witness the rumored "best place to see the sunrise." According to most tourists: the most popular place during sunrise is Angkor Wat. So that means everyone is expected to flood the temple, and to avoid the crowd, we took the other path, a crowd like that of Phnom Bahkeng during sunset will defeat the purpose of watching the sunrise.
TIP: Most tuk tuk driver will be familiar with Srah Srang. If you are on a packaged tour, your tour coach may also stop by here for you to have a look. However, you are likely to see it somewhere in the day time, not the perfect time for shutterbugs. Some may charge an additional $5-$10 if you want to go there before sunrise. If you're traveling independently from Siem Reap, the fastest way to reach Srah Srang is to take the road from Siem Reap to Angkor Wat. When you see the moat of Angkor Wat, turn right (turning left takes you to Angkor Thom). After a short distance, you will pass Prasat Kravan on your right. After another distance you will see Banteay Kdei on the left, and Srah Srang on the right.
Srah Srang is right in front of Banteay Kdei (Dancers' Hall)
It was our third day in Siem Reap. Misty-humid (relatively clean) air of summer night penetrated every single alveolar sac of my lungs. Upon waking-up and after a quick shower, I grabbed my sling bag, passport, wallet, a bottle of water and my camera. I jumped off Prohm Roth Hotel in my mismatched outfit, Piron (our Tuktuk driver) was waiting outside flashing a big smile as usual.
Two blocks away after hitting the road, we realized that the ascaris lumbricoides' in our guts were already begging for food. So we stopped at the town center to grab something to eat, early morning vendors are selling freshly baked baguettes and French bread. I suddenly missed our pan de sal in Sampaloc (darn).
Still sluggish and half awake, Monette and I tried covering our faces with towel to prevent ingesting flying insects hitting our faces as we run 90 kph across the highway in the middle of the lush forest. In no time, we reached the 900 year old man made lake, around 10-15 tourists (and an army of vendors, mostly kids) were already in the site, excited first timers like us were either setting-up cameras or choosing a good spot for meditation. I stood at the edge of the flatform landing facing the glassy water of the baray—a good vantage point to watch and take pictures of the sunrise.
Then we waited…
When the sun starts peeking out the horizon, everyone froze, speechless and jaws dropped on the floor. In a matter of minutes, we saw the color of the sky changed seamlessly.
From jet black to prussian to palatinate to crimsons to salmon to vermilion to chartreuse
It was truly the best sunrise that I witnessed to date.
It's very timely to post this at the eve of the turn of the decade. The experience at Srah Srang was revitalizing, a metaphor of rebirth and fresh start. Like the sun kissing the new day ahead, anticipating the arrival of the morning light made me reflect not only on the recent days but the year that was.
I felt brand new.
The second decade of the 21st century is here.
oooh, 2010—so Jetsons! love it!


text:
OMG! Spread salt on icy roads?
The State of Oregon is going to test it out for five years on stretches of I-5 and U.S. 95 way down near the Cali and Nevada borders. Don't know what the test is supposed to show. We're pretty sure that the chemistry is going to work.
Hey, just thinking out loud here -- but does fluoride melt ice?

subset: commoncrawl


text:
What do you get when you combine dogs, Victoria Secret models, aliens and drag queens? The Tompkins Square Halloween Dog Parade, of course! I know we've been writing a lot about dogs and Halloween, but we just had to share some more photos from this years event.
A week and a half before Halloween, the event had perfect weather, smiling faces and a ton of dogs dressed to impress, make you giggle and appreciate how dogs can bring people together. People of all ages and backgrounds took pride is getting their dogs in the spotlight and a chance to win some fun prizes from local dog companies like EverMore pet food and Barkbox.com.
The $5 admission fee went towards maintaining the dog run as one of the most well kept dog spots for the folks in the East Village. A good cause and some great fun. Can't wait till next year.
Be warned, the cuteness factor is off the charts.
And last but not least …
For more photos, checkout our Facebook Album.
Are you and your dog prepped for the actual day of Halloween?


text:
Regional Centre of Biotechnology (RCB) released job advertisement in employment news for recruitment of 15 Scientist, Technical Assistant. Regional Centre of Biotechnology seeking 12th, Graduation Degree, Post Graduation, Ph.D qualified candidates to appoint as Scientist, Technical Assistant on Full Time basis in New Delhi. RCB Recruitment 2014 invites Online/offline application on or before 10 september 2014. Candidates are advised to dowload detailed RCB Recruitment 2014 - Jobs advertisement from Regional Centre of Biotechnology website www.rcb.res.in before Apply Offline. Check detailed individual post information like - RCB exam pattern, Syllabus, eligibility Criteria And experiences Requirement, age limit, selection criteria for each vacancies.
To Explore more relevant jobs opportunities visit our GRADUATE GOVERNMENT JOBS page or check ALL LATEST GOVERNMENT JOBS OPENING 2014. Do not forget to visit JobsOK again for RCB admit card 2014, and RCB Results 2014.
Regional Centre of Biotechnology (RCB) Recruitment 2014 Government jobs details -
Hiring Organization - Regional Centre of Biotechnology
Post Name and Total No. of Vacancies - 15 posts
1. Scientist - 03
2. Manager Administration & Finance) - 01
3. Law Officer - 01
4. Technical Assistant - 03
5. Accountant - 01
6. Data Entry operator - 03
7. Receptionist Cum Media Operator - 01
8. Multi Tasking Staff - 02 posts
Employment Type - Full Time
Selection Procedure - Written Exam, Interview
Location - New Delhi
Base Salary and Grade Pay - INR Rs. 50000-70000/-, 45000-60000/-, 20000-25000/-, 18000-20000/-, 15000-18000/-, 10000/-..
Educational Qualification - All interested candidates must posses 12th, Graduation Degree, Post Graduation, Ph.D or its equivalent qualification from a recognized Board / University. For post wise qualification for specific job openings go to detailed advertisement
Age Requirement - Age of candidate should lie between 28 - 45 Years (both inclusive).Read detailed advertisement to check age limit of individual posts. Age relaxations will be applicable as per the Central/State Government rules
How To Apply - All Eligible and interested candidates have to apply in prescribed format which can be Download official website www.rcb.res.in . After Filling The application form, candidate must send hard copy of application along with relevant testimonials (Mentioned In Detailed Advertisement) to the following Address before or on 10-09-2014.
Address -
RCGM Secretariat, Department of Biotechnology, Room No. 804, Block 2, 8thFloor, CGO Complex, Lodhi Road, New Delhi 110003.
Official Website - www.rcb.res.in .
Important Dates To Remember-Last Date for Receiving of Online Application Form Is: 10-09-2014
For free job alerts like @ Latest Government jobs opening 2014 facebook page for Job updates on your Timeline and also Subscribe for JobsOK Employment Newsletter - Email subscription.


text:
Home | Contact | Media | Sitemap | Employee Login
Attend a few social occasions, wearing a decent wrist rolex replica watches, it is your best choice! High purity cold tone Mens replica hublot watch wearing a formal and simple style, will make you even more out of the ordinary, man of style will show more most incisive! For a female friend, wearing a stylish, popular, dignified, beautiful ladies swiss replica watches, will make you more charming charming appearance and personality. A casual glance at replica watches your wrist, an elegant temperament flowing through the wrist!


text:
Brazil deploys troops in Rio as crime surges
Brazilian president Michale Temer says police have been deployed in Rio de Janeiro as part of a plan to combat rising crime in the city. Rough cut (no reporter narration)
ROUGH CUT. NO REPORTER NARRATION. Armed forces troops have been deployed throughout much of the city of Rio de Janeiro and surrounding areas as part of a plan to combat organized crime in Brazil's second largest city. Army troops carrying rifles and armoured vehicles were seen along bike paths and roadways around the city on Saturday (July 29) after first being deployed on Friday (July 28). The air force and navy are also participating in the operation. Brazilian President Michel Temer said the operation was aimed at "preserving public order" as the security situation in Rio continues to worsen. Defence Minister Raul Jugmann warned dramatic results would not come easy and would not be seen from one day to the next. The plan calls for the deployment of more than 10,000 troops and the government expects the armed forces to remain until at least the end of 2018.


text:
Computerized expert systems for various farming operations like irrigation have been around for a number of years now, but they're continually being updated, evolving with the needs of growers.
"We want the software to meet the needs of producers," says Staci Ingram, technician with the National Peanut Research Laboratory in Dawson, Ga., which has created several such programs, including Irrigator Pro for peanuts, cotton and corn.
"Irrigator Pro for peanuts was developed more than 20 years ago," says Ingram. "We're looking at taking a conservation-minded approach to irrigation by meeting the physiological needs of the plant, but not using more water than is necessary."
This particular system is designed to manage peanut irrigation and pest management decisions. The objective is to improve economic returns for irrigated peanut production and reduce risks associated with aflatoxin, foreign materials, immaturity, off-flavor, chemical residues, and negative environmental impacts.
Irrigation recommendations, explains Ingram, are based upon more than 25 years of scientific research data and information. To begin the program, growers enter field data including planting date, variety planted, previous crop, soil type and irrigation capacity.
Then, they place a digital minimum/maximum soil thermometer in the field, in the row, a few weeks after the crop has emerged. They also place a rain gauge in this same area as well as outside the pivot to record rainfall. The sensors in the field should be marked with flags because they will be difficult to find later in the season.
Users of the program begin by taking soil temperature readings a couple of times per week and asking for the recommendation which will advise if and how much to irrigate or when to check soil temperatures again.
Generally, irrigation recommendations are made to maintain soil temperatures and water in the optimum ranges. The program generates graphs showing data in relation to optimum and minimum zones, helping diagnose problems that may occur.
Extensivley evaluated, validated
Irrigator Pro for peanuts, says Ingram, has been extensively evaluated and validated in replicated research plots as well as commercial trials with cooperating farmers. Yield increases of more than 300 pounds per acre and 2 percentage point increases in Sound Mature Kernels and Sound Splits have been demonstrated. The program has been validated in all major U.S. peanut-producing regions, and recommendations are specific to growing regions.
Irrigator Pro for cotton and corn have also been developed and validated and have recently gained significant adoption, says Ingram. The requirements vary from the peanut model with installation of three soil moisture sensors at depths of 8 inches, 16 inches and 24 inches. Readings are taken during the season to collect the data to be input into the model to generate recommendations.
Growers should follow manufacturers' preparation and installation recommendations that accompany the sensors, test them, and then install at depths of 8, 16 and 24 inches in the row, after the crop has emerged. Rainfall events should be recorded from the day of planting until sensors are installed and readings are entered.
Data specific to each field is required such as soil type and irrigation capacity.
To begin entering data, growers simply enter farm information, then individual fields, and the data for those fields as it occurs. When sensor readings are entered, recommendations can be retrieved advising if and/or when to irrigate, an amount, and when to check the sensors again. A comment section is also included for any information that you may want to reference later in the season.
MoisMis 2020 is an Xcel spreadsheet and workbook that operates in Xcel 2007 but is also compatible with Xcel 97-2003.
The program uses Daily Data inputs of rainfall, irrigation and soil moisture tension (SMT) at 9 inches and 18 inches with crop water-use curves to schedule irrigation up to five days in the future. Rainfall and SMT inputs are needed only two times per week, three to four days apart.


text:
This May we begin our fifth Forest Monitoring season. We already have over 200 monitoring locations throughout Summit County where volunteer citizen scientists track the health of our forest lands. We have a team of dedicated volunteers, but need more peo…
FDRD NEWS Title
... Recent Posts Categories https://fdrd.org/news/volunteer-opportunities/meet-your-forest-volunteer-be-forest-monitor-column/
Dispersed camping at the Dillon Ranger District offers campers with a unique experience to stay in more isolated areas of the national forest, outside of developed campgrounds, without necessarily having to travel long distances into the wilderness.
FDRD NEWS FDRD And Summit Seniors Restore Illegal Campsites Dispersed camping at the Dillon Ranger District offers campers with a unique experience to stay in more isolated areas … https://fdrd.org/news/trail-information/fdrd-and-summit-seniors-restore-illegal-campsites/
Take a look at how you can create an experience to remember with Friends of the Dillon Ranger District! To view the FDRD Photo Gallery Click here
Need assistance with this form?
Contact FDRD
Friends of the Dillon Ranger District P.O. BOX 1648, Silverthorne, CO 80498
PHONE: 970.262.3449 EMAIL: email@example.com


text:
A picturesque representation of the Alpine mountain ranges and the scenery that comes with it, the state of Tyrol is a tourist hot bed round the year. This comes down to the presence of some of the leading ski resorts in the world in the northeast and the southeast. The state has part of the Princely County of Tyrol as well.
Tyrol, located entirely within the Eastern Alps, is a federal state situated in the Western part of Austria. Innsbruck is the capital of Tyrol. Tyrol has always been famous for its universities especially medicine. There are 14 large towns in Tyrol famous for their ski resorts and other fun activities. People visiting Tyrol leave behind their worries and escape the everyday stress and become one with nature. There are many things to do in Tyrol, which includes a number of outdoor activities offered both in winter (alpine skiing, tobogganing, cross-country skiing) and summer (rock climbing and hiking). Other things to do in Tyrol include visiting the historical and cultural places the city is rich in and famous for. From cultural events to museums, you will be enthralled by the beautiful people and well preserved history of the country. You will get to experience the traditional celebrations and customs of the towns and villages of Tyrol. When the temperature rises in summer, people take to the number of crystal clear lakes where you can get fresh air and cool off in the summer heat. There are lush green meadows and beautiful landscapes that make this place worth visiting in all the seasons.
You can travel to Tyrol via air as the city has an international airport. Travelling within the city is also not a problem because of the well-maintained transport systems including and international road and a chain of railways and motorways. Separated by a 20 km wide strip, the state of Tyrol is divided into two parts, both famous for their own cultures and traditions. Tyrol is full of romantic castles and lakes present amid the natural beauty of the Alps found all over the area. Once you reach Tyrol, you will notice that a few days will not be enough to enjoy all the beautiful locations and the wide number of things that are there to do in Tyrol. Full of rich history, outdoor activities, cultural and natural history, Tyrol is a famous tourist destination from people all around the world. From museums to ski jumping, Tyrol offers something interesting for every person irrespective of their interests and the age group they belong. You can visit zoos and admire the spectacular architecture of old building located in the heart of the city. Tyrol never fails to entertain all of its tourists in one way or the other. The main places to visit in Tyrol include, but are not limited to, Ambras Castle, Achen Lake, Hohe Salve, Arlberg, and Aguntum.
Located in hills above Innsbruck, Ambras Castle is a renaissance palace and castle which is one of the must visit place in Tyrol and definitely needs to be added in your list of things to do in Tyrol. Ambras Castle is one of the most famous tourist attractions in the city. Built in the 16th century, the castle holds great cultural and historical importance. Ambras Castle is also the oldest museum in the world owing to the collection of the cultured humanist from the House of Habsburg. There are a number of things to do in Ambras Castle. You can visit the palace and see the collections in the museum founded by Ferdinand II. The museum was constructed using the most advanced and modern ideas of his time. You can visit the armories where you will get to see some of the rare armors of the 15th century. Ferdinand was very particular about the collection of armors and it can be seen from the collection present in the armories. You can see a collection of armors from famous commanders of 16th century displayed by the name of Heldenrüstkammer. You can also visit the upper and lower castle, both of which are architectural masterpieces you will not find anywhere else in the world.
Located north of Tyrol, Achen Lake is a highly recommended place to be added to the list of things to do in Tyrol. Having a depth of around 133 meters, it is the largest lake of the federal state of Tyrol. Achen Lake and the Achen Valley together attract a large number of tourists visiting Austria each year. The place is rich in natural beauty and beautiful landscapes. The water in the lake is clean, making it close to drinking water. Since it is an alpine lake, the temperature of water usually does not go above 20°C. The wind conditions and size of the lake make it a suitable and popular spot for windsurfing. There are a number of things to do in Achen Lake. Having an excellent hiking trail in the surrounding mountains, you can spend time hiking in the hills. Touring Achenesee on a cruise ship is also one of the most popular things to do here. You will also find some cycling trials that you can take to explore the natural beauty of the place further. You will get many inexpensive private accommodations in the nearby areas that can be made a base for exploring the beautiful surroundings of the Achen Lake.
It is highly recommended that you add visiting Hohe Salve in your list of things to do in Tyrol. Hohe Salve, a mountain located in Tyrol is also nicknamed the Rigi of Tyrol. The mountain is 1,828 m in height and along with the beautiful weather you find here, makes one of the most famous and popular tourist destinations in Tyrol. The mountain provides an amazing view of the Zillertal Alps and the High Tauern, lying right next to Hohe Salve in the north. Hohe Salve is also famous owing to its conical appearance. One of the many things to do in Hohe Salve includes hiking the mountain and going on to see an old pilgrimage chapel, a transmission mast, and a restaurant. During winters, the mountain is a part of the ski region of Skiwelt and becomes a more attractive place because of the skiing trails it offers to the tourists. Owing to the conical shape it has, Hohe Salve is also a popular starting point for paragliding lovers that come here in large numbers. The place is a hub of natural scenic beauty and is a must visit place if you are travelling to Tyrol in the near future.
If you are visiting Tyrol, your list of things to do in Tyrol will never be complete without adding Arlberg to it. A mountain range between Tyrol and Vorarlberg, Arlberg is a famous tourist attraction of the area. There are a number of popular places and things to do in Arlberg including some famous ski resorts. The most popular ski resorts here include Zürs, Stuben, Lech, St. Anton and St. Christoph. Having more than 90 cable cars and a number of hotels and resorts, you can never get bored here at the Arlberg irrespective of which season you choose to visit the place in. There is plenty of stuff to do in summer and winter. You can hike on the mountains and enjoy the mesmerizing landscapes of the area and can also try mountain biking. In winters, you can do everything you can with the snow all around, including skiing. Having some of the best skiing resorts, the Arlberg is a must visit place for all the people who plan to visit Austria in general and Tyrol in particular. You can also visit the Arlberg tunnel that connects Austria to Switzerland or can visit one of the many restaurants and hotels to enjoy your time there with your friends and family.
Part of the highest mountain range in Europe, the Alps of Tyrol are different from their cross border counterparts. Instead of having treacherous peaks, the Alps boast stunning mountain ranges that wear a carpet of snow in the winters and shed that carpet to lush green meadows in the spring. There are lots of things to do in Alps including hiking in the summers and taking part in the skiing excursions in winter time. The leisure facilities and skiing resorts in the Alps offer comfort and excitement to all. A booming area for tourism, you can visit the Alps with your family and come face to face with nature, savoring its beauty and relaxing in the cradle of lush green meadows. There is something for everyone up here at the Alps with a variety of sports round the year. Once you visit the place, you won't be able to enjoy the area to the fullest until you enjoy the local culinary delights as part of your list of things to do in Alps . True to their traditions, their food is different and ideally suited to the high altitude of the Alps. During the course of your stay, you will also get a chance to meet the locals and know more about their culture and traditions.
The resting place of Emperor Maximilian I and Tyrol's national hero Andrea Hofer, Hofkirche is a gothic church that is located in the Old Town section of Innsburk, Austria. Built by Ferdinand I, for his grandfather back in 1553, the Court Church, as it loosely translates to, has a rich history of arts, pre and post renaissance. You won't be able to enjoy the church unless you have a breakdown of the history about the church. Hence, one of the first things to do in Hofkirche is to visit their multimedia display which takes you on a tour of the church. Not only that, it offers a unique experience since it has one of the largest collection of renaissance works of Germany. If you like to look at sculptures and artworks, the church is a place tailormade for your tastes with its distinct collection of huge bronze statues. Also, if you have time, you can always take out your camera and take pictures of the beautiful surroundings. A major activity among things to do in Hofkirche is bird watching as a number of different species reside in the area, while others come to it, especially in the summer time.
Located right next to the Hofkirche, the Tyrolean Folk Art Museum is considered one of the finest museums in the region. There are very few historical and cultural artifacts of the Tyrol region and it is interesting to note that the most important ones are housed in this museum. The museum building is surrounded by an arcaded Renaissance courtyard. In addition to housing some important works of art, the museum is open for tourists with a number of different exhibitions being conducted permanently. Your things to do in Tyrolean Folk Art Museum should include visiting these exhibitions that contain extensive collections of household items, handicrafts, textiles, glass and pottery on display. If you like sightseeing, the rooftop of the museum offers a stunning view. If you are new to the Innsbruck area, one of the first things to do in Tyrolean Folk Art Museum is to climb up to the top and gaze at the stunning landscape of the city. If you are visiting with your family, there are many nice eateries and stalls for souvenirs and memorabilia that can be bought to help you remember the trip for a long time.
If you are a person interested in history and archeology, consider adding Aguntum to your list of things to do in Tyrol. Excavations are still underway at this historical site which is believed to be the centre of commerce and trade under the emperor Claudius about 2000 years ago. Aguntum was a trading and mining centre that made use of local metals like zinc, iron, copper and gold, turning them into useful goods and transporting them via Roman roads. The locals also exported milk products and wood to earn their living. If you are looking for the things to do in Aguntum, you can begin by taking a walk through the excavations to find out more about the history of the place. You can then consider visiting the glass walled museum showcasing the Roman roots in the area. There are various objects on display including coins, jewelry, potter, clothes, and bronze objects that you can observe here at the Aguntum.


text:
Plain English Summary
Background and study aims
Alpha-mannosidosis is an inherited condition caused by a lack of alpha-mannosidase (LAMAN), an enzyme found inside then body's cells that normally breaks down complex sugars. Lack of this enzyme leads to a progressive loss of motor and mental ability. People of all ethnicities and both genders may be affected by the disease. The first symptoms are loss of hearing, coarse facial features, reduced mobility and mental retardation. The symptoms appear over time. Alpha-mannosidosis is very rare, affecting only 1 out of 1,000,000 people. Lamazym is an identical copy of the natural LAMAN enzyme. It is administered into the bloodstream to replace the LAMAN enzyme. Lamazym has been tested on animals with promising results but has been administered to people in only two studies. This study will test the long-term effect and safety of the drug in patients with alpha-mannosidosis.
Who can participate?
Patients with alpha-mannosidosis who participated in the previous two studies (EudraCT numbers 2010-022084-36 and 2010-022085-26).
What does the study involve?
All of the patients are treated with Lamazym infused directly into the bloodstream each week and the effects are assessed after about 3 and 6 months. Safety is tested by monitoring the patient's blood pressure, blood chemicals, production of antibodies, and side effects. The effectiveness is measured by monitoring the reduction of sugar chains in the blood and cerebrospinal (brain and spine) fluid. An MRI scan of the brain will be conducted, as well as a walking test, a lung function test, a hearing test, a movement test and a mental test. Once this study has been completed, if no safety issues arise, the patients are offered continued treatment until the product is available on the market.
What are the possible benefits and risks of participating?
As with most enzyme-replacement treatments, there is a possible risk of patients developing allergic and/or immune reactions to the enzyme. Animal studies and the first studies on human patients have not shown any serious side effects to the dose planned for patients in this study. The patient's parents must inform the study staff if they observe anything unusual about the patient. The investigator will monitor any side effects that arise during the study and will take all relevant measures in order to treat any such reaction. The patient may experience discomfort after the catheter has been implanted in the bloodstream to help with treatment and the taking of blood samples (the patients will already have had this catheter implanted as part of the first study). MRI scanning of the brain will require general anaesthestic. Fasting before the MRI scan will therefore be necessary. Cerebrospinal fluid samples will be taken while the patient is anaesthetised. The taking of cerebrospinal fluid may cause headache. The movement test and the mental test will take some hours and may make the patient tired.
Where is the study run from?
The patients will be invited from hospitals all over Europe for treatment at the Copenhagen University Hospital (Rigshospitalet). It may also be possible for them to be treated at a hospital in/near their home countries.
When is the study starting and how long is it expected to run for?
June to July 2012.
Who is funding the study?
The study is financed by the EU.
Who is the main contact?
Laura Crowther
Trial website
Contact information
Primary contact
Miss Laura Crowther
Contact details
University Research Floor (5th Floor)
Royal Manchester Children's Hospital
Oxford Road
United Kingdom
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
12605, rhLAMAN-04
Study information
Scientific title
A multicenter, open-label trial of the long-term efficacy and safety of Lamazym for the treatment of patients with alpha-Mannosidosis
Study hypothesis
Alpha-Mannosidosis is a rare lysosomal storage disorder caused by deficiency of the lysosomal enzyme alphamannosidase. The effect of the enzyme deficiency is accumulation of mannoserich glycoproteins in the tissues. It is inherited in an autosomal recessive manner. The typical symptoms include facial characteristics, mental retardation, ataxia, hearing impairment, impaired speech, recurrent infections, skeletal abnormalities, muscular pain and weakness.
There is a slow progression of symptoms over several decades. The longterm prognosis is generally poor. The clinical variation is considerable, encompassing a continuum from mild to severe. Most of the patients are diagnosed in their first or second decade of life. Increased levels of mannoserich oligosaccharides in urine, reduced activity of alphamannosidase in leukocytes and finding of two pathogenic mutations in MAN2B1 identify the patients. Currently no effective clinical treatment for alpha-Mannosidosis exists. Medical treatments are confined to be supportive and symptomatic. Lamazym is recombinant human lysosomal alpha-Mannosidase developed as an intravenous enzyme replacement therapy (ERT) for the treatment of alphaMannosidosis.
The current trial is being performed to evaluate the long-term efficacy, safety and tolerability of Lamazym treatment in patients with alpha-Mannosidosis. If successful, the enzyme replacement therapy is expected to be given lifelong, with the aim of normalizing the mannoserich oligosaccharide levels in the tissues, altering the progression of the disease and thereby preventing or reducing abnormalities from being developed and hopefully improving the patient's condition and quality of life.
Ethics approval
Study design
Non-randomised; Interventional; Design type: Treatment
Primary study design
Secondary study design
Non randomised study
Trial setting
Trial type
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Topic: Medicines for Children Research Network; Subtopic: All Diagnoses; Disease: All Diseases
Infusion of Lamazym 1 mg/kg given weekly for 6 months
Intervention type
Phase II
Drug names
Primary outcome measure
Reduction of Oligosaccharides in blood serum and cerebrospinal fluid (CSF) and an improvement in the 3 minute stair climb
Secondary outcome measures
No secondary outcome measures
Overall trial start date
Overall trial end date
Reason abandoned (if study stopped)
Participant inclusion criteria
1. The subject must have participated in the phase 1 trial (EudraCT number: 201002208436) and phase 2a trial (EudraCT number: 201002208526)
2. Subject or subjects legally authorized guardian(s) must provide signed, informed consent prior to performing any trial related activities (trial related activities are any procedures that would not have been performed during normal management of the subject)
3. The subject and his/her guardian(s) must have the ability to comply with the protocol
Participant type
Age group
Target number of participants
Planned Sample Size: 9; UK Sample Size: 1
Participant exclusion criteria
1. The subject cannot walk without support
2. Presence of known chromosomal abnormality and syndromes affecting psychomotor development, other than alphaMannosidosis
3. History of bone marrow transplantation
4. Presence of known clinically significant cardiovascular, hepatic, pulmonary or renal disease or other medical conditions that, in the opinion of the Investigator, would preclude participation in the trial
5. Any other medical condition or serious intercurrent illness, or extenuating circumstance that, in the opinion of the investigator, would preclude participation in the trial
6. Pregnancy
7. Psychosis within the last 3 months
8. Planned major surgery that, in the opinion of the investigator, would preclude participation in the trial
9. Participation in other interventional trials testing IMP except for studies with Lamazym
Recruitment start date
Recruitment end date
Countries of recruitment
Belgium, Denmark, France, Germany, Poland, Spain, United Kingdom
Trial participating centre
Royal Manchester Children's Hospital
United Kingdom
Funder type
Funder name
European Commission
Alternative name(s)
Funding Body Type
government organisation
Funding Body Subtype
Federal/National Government
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list


text:
The purpose of the Spiritual Guide is to increase awareness of how God expects us to walk in His word and identify the principles involved in our Faith walk. The guide is designed to teach believers how to find and maintain faith, evaluate our daily walk and draw closer unto God. In reviewing the spiritual guide, the goal is to be renewed, empowered and ready to help others find faith and favor in God.
Dr. Alfreda Emonya Love has devoted her professional life to serving the Lord in some capacity. Since transitioning into ministry, Alfreda continues to follow in God's word, but in an entirely different fashion.
By serving the people, community, and her colleagues, Alfreda reaches out to others through the spoken word via ministry workshops. She coordinates various events and publicizes them in an effort to spread the word of God, and she does so with love in her heart and compassion in her soul.
In the business of soul saving, Alfreda's calling makes her step out of her comfort zone in order to make the vision of the ministry come alive. Making time to sit down and plan for events, as well as studying the bible isn't as easy as it sounds.
Alfreda is also an administrator at La Vega Elementary. She's written three award-winning stage shows during her time as a writer. Friday's Kinfolk, Brother I Will Dance at Your Wedding and I Got to Have Faith. She's also co-written three articles with Dr. William Kritsonis on education.
As an active member of Phi Delta Kappa, Alfreda likes to spend her days with family, reading, traveling, writing, organizing and promoting. She also enjoys listening to gospel music. She has a loving family, especially her mom, who is her biggest fan.
Alfreda earned a Bachelor's in Education, English, and Health from Baylor University, followed by a Master's in Education Leadership from Prairie View A and M/Texas A&M University and finally a Ph.D in Educational Leadership from Prairie View. She thanks God and her family for her many achievements in life. Dr. Love is a member of the Greater Ebenezer Baptist Church in Waco, Texas.


text:
Authored by Vince Russell on 14 April 2007 at 07:14PM
Current rating:
Filed under: Vince Goes Ape
Vince Kong at the football
It's been a fair while since Nottingham Forest were the toast of Europe, nowadays we're desperately trying to get out of the third tier of English football. So I thought I'd introduce Vince Kong to the beautiful game, sadly beautiful it was not!
Millwall are a South East London side better know for their fighting skills off the pitch rather than the football on it, so I did feel a little nervous turning up in my gorilla suit, and I could sense Lucy wasn't too happy about it either.
I left with the words "don't get beaten up" ringing in my ears and caught a train to Waterloo. The journey was quite fun, a bunch of ten year olds on the train were amused by my costume so I asked them to take my picture, they seemed to go into a huddle and I heard "he wants us to take his photo!" from within, then one of them was thrust forward and took my photo (thank you!).
It got a bit boring after that, so I decided to walk through the train, that was also a bit dull, so I went a sat in first class and scared the crap out of some chap having a little sleep, not on purpose of course! He found it funny though and tried to get me to scare his mate who was still asleep, I couldn't do it.
From Waterloo I took a couple more trains before arriving at my destination. I asked a young chav to take my photo but he refused (he was clearly Millwall fan), so I just carried on walking to the stadium.
Getting through the turnstiles was very amusing, the lady taking my ticket let out a little scream before rolling about laughing, then she dashed out of her booth clutching her mobile phone and desperate to take a picture. This little pantomime went on for about five minutes before see finally took my ticket and let me in. Next up was a good frisking by a guard, well, more like a cursory pat down (it was pretty hot and I reckon he could smell me before I stepped up).
From there, it was nothing but disaster! I was approached by a steward who asked me to remove my head (I resisted cracking a few jokes). He told me in no uncertain terms that if I put my gorilla head back on, I would be ejected from the ground. I then took my seat and watched what can only be described by a "pile of old crap", and we lost one nil.
Rather than heading back to Twickenham after the game, I was due to visit the in-laws in Biggleswade, which is about fifty miles away. So after a few more trains, I arrived at Kings Cross. Again, I was told to remove my head, "for security purposes" apparently! I did take it off, but put it back on when I got round the corner and caught my train to Biggleswade.
And so, after over six hours and seven trains as Vince Kong, I arrived at a small village in Bedfordshire, I don't think I need to tell you how badly I smelt, I was dripping with sweat and desperate for a beer. I should look on the bright side of the day though, if Forest had won, superstition would have dictated that I wear the suit for the rest of the season. Actually, that might have been fun!
Photo's from the Vince Kong at the football
Authored by Vince Russell on 14 April 2007 at 07:14PM
Current rating:
Filed under: Vince Goes Ape
Comments about "Vince Kong at the football"
mrgrooism said
Vince Kong Lives!!! WOOO-HOOOO!!!
14 April 2007 at 08:47PM
nffcblog said
I love the idea of going to random events dressed as animals... fantastic!
14 April 2007 at 10:36PM
Junglynist said
quality, sheer quality!! yooooooo reeeddddsss!!!
15 April 2007 at 12:57AM
gouldin said
i woz ryt bhind this fing wen da women at da desk wanted a pic as wel :)
15 April 2007 at 02:16PM
The Wife said
Awesome. The Biggleswade natives are still stunned I think.
15 April 2007 at 06:14PM
Alex said
Biggleswade is full of people who look like Gorillas! You must have blended in quite well there!
16 April 2007 at 09:48AM
Ash said
very funny indeed. Im surprised they havent sent the gorilla police after you seeing as though your bothering every one wiht the daily zombie like routine of life! lol
16 April 2007 at 01:01PM
Bob said
26 January 2009 at 01:30PM


text:
Galle Fort, Sri Lanka
Nestled within the ramparts of the 17th-century Galle Fort, Amangalla is an extraordinary sanctuary from which to explore the fascinating culture and tumultuous history of this intriguing Sri Lanka UNESCO World Heritage Site.
Named after the Sanskrit word for 'peace', and the Sinhalese word for 'Galle', the Amangalla inventively reveals the rich legacy of its surroundings. The 21 bedrooms, chambers and suites are decorated in tasteful colonial style with four-poster beds, polished Burmese teak floorboards and free standing bathtubs. The rooms offer a variety of views from Galle Fort itself to the immaculate garden. For those wanting the ultimate in luxury, there is also the magnificent Garden House, a two-storey house featuring a private terrace and balcony with leafy treetop views as well as a pantry serviced by a private butler.
There is a large swimming pool at the centre of the hotel, offering a cool respite from exploring the Fort and surrounding areas. In keeping with the ambience of the hotel, the spa is known as 'The Baths'. Recapture memories of a bygone era of 'taking the waters' and restoring the body whilst being pampered in one of the five treatment chambers leading off an arched hallway. Hydrotherapy pools, ayurveda treatments, a yoga and meditation pavilion, barber shop and a hair salon all compliment this experience.
The most enjoyable activity on the doorstep of Amangalla is to experience the Fort on foot. A leisurely walk will take you past the old Dutch Church, the Governor's house, the spice warehouses, the town hall and onto the Lighthouse and the sea wall and ramparts. There is nowhere better to be at sunset than walking along the ramparts of the Fort, watching the last ball of a cricket match, children flying kites and the general townsfolk gathering together.
Lightfoot Travel loves…
"Sipping on a cold gin and tonic on Amangalla's front veranda, transporting yourself back in time as you observe the hustle and bustle of daily life within the Fort."
Amangalla Information
- Location: Inside Galle Fort. 3 hours drive from the International Airport
- Accommodation: 29 rooms, including 8 suites and 1 private Garden House with butler
- Activities:Shopping and restaurants in Fort, beaches near Galle, complimentary afternoon tea with home-made scones
- Facilites: Pool, spa, library, restaurant, gym, yoga
- Weather: Avoid May to July monsoon
- Children: Children are welcome – extra beds are available and babysitters are complimentary. The Library has a large selection of games, books and toys for children of all ages


text:
It's been a couple of months since my last empties post and my can you tell! My box of used products is the most full it's ever been so to save some time I will link below other posts for the products which have been around these parts before and will give more detail of the products which are new to me.
- Garnier Body Intensive Ultra-Replenishing Lotion - here
- Herbal Essences Clearly Naked Dry Shampoo (there was actually two of these!) - here
- The Body Shop Camomile Cleansing Oil - here
- The Body Shop Vitamin E Moisture Serum - here
- The Body Shop Vitamin E Overnight Serum-In-Oil - here
- Soap & Glory One Heck Of A Blot Primer - here
- Soap & Glory Archery Brow Pencil - here
- Re-Gen Cream - here
- No7 Soft & Soothed Gentle Toner - here
- Soap & Glory Flake Away Exfolliator - here
- Bumble & Bumble Thickening Dryspun Finish - I really liked this product. It added texture and volume to my hair without leaving a greasy residue or weighing it down
- Bumble & Bumble Thickening Hairspray - again I loved this. I put it through my hair while wet and dried as normal to find it helped thicken my hair without making it feel like there was a lot of product in it
- Sanctuary Spa 5 Minute Thermal Detox Mask - I really enjoyed using this. It was the first face mask I've used which heats up and the first time I used it I did panic slightly by the warmth but once I was used to it I really enjoyed using this. I also enjoy how quick it is to use. Many face masks have to stay on for 10mins or so but after just 5 this has worked its magic
- Elizabeth Arden Eight Hour Cream Skin Protectant - I really like this product, who doesn't!? It's been the best product for dry lips I've used but recently I found a great dupe with a smaller price tag (you can read that product here)
- Soap & Glory Orangeasm Body Wash - this bad boy has lasted me ages! And smells incredible...soap & glory can do no wrong with the toiletries
- Garnier Moisutre Radiance Dairy Energising Gel Moisturiser - another win for the new products. I really like the cooling effect of this moisturiser and the fact it was a gel. It really helped to waken my skin up first thing in the morning and soaked in beautifully
- The Body Shop Body Butter in 'Coconut' and 'Shea Butter' - these smell amazing, melt into the skin effortlessly and leave skin smooth as ever! I love them!
- Maybelline Instant Anti-Age Concealer - I used this years ago and after seeing it on youtube so much I just had to buy it again and it was every bit of great as I remember. I'm not a massive fan of the applicator at the end but it does the job (not in the most hygienic way) but the product itself is great at brightening up the under eye without creasing at all throughout the day
Yeah...I did warn you there was a lot of empties! So well done for making it to the end. Let me know if you've also used up any of these products and what you thought of them.
Thanks for reading
Iona x
Bloglovin'- TheLittleLassie
Twitter- ionaTLL
Instagram- thelittlelassie
Youtube - TheLittleLassies


text:
Shorpy is funded by you. Help by purchasing a print or contributing. Learn more.
Our holdings include hundreds of glass and film negatives/transparencies that we've scanned ourselves; in addition, many other photos on this site were extracted from reference images (high-resolution tiffs) in the Library of Congress research archive. (To query the database click here.) They are adjusted, restored and reworked by your webmaster in accordance with his aesthetic sensibilities before being downsized and turned into the jpegs you see here. All of these images (including "derivative works") are protected by copyright laws of the United States and other jurisdictions and may not be sold, reproduced or otherwise used for commercial purposes without permission.
Vintage photos of:
March 15, 1926. Washington, D.C. "Lady Cathcart, Austin Fairman & George Vivian." Countess Vera Cathcart, playwright-star of the theatrical flop "Ashes of Love," whose visit to America was notable mostly for a scandal involving a champagne-filled bathtub. National Photo glass negative. View full size.
How very dull of you unreconstructed types to respond to such an intriguing photo with nothing but sniping about her looks. I'm quite taken with her: she seems to have been a fascinating and determined character, with excellent earl-seducing skills.
Bad review of the play, quoted in a McCall's article:
"This reviewer must admit that he was strongly impressed with the countess in her efforts for entrance into the country, especially so when the opposition was on ground of moral turpitude, but had the opposition been on the ground of her claim as an actress, we would have to be with the immigration people."
It's a fantastic image of George Vivian. I wonder if he was directing?
"I keep smelling insecticide, or is it really cheap bootlegged champagne?"
It looks like she had a wandering eye, in more ways than one.
It was indeed a flop. The three-act play opened its Broadway run at the National Theatre (now Nederlander) on West 41st Street on March 22, 1926, and closed after only eight performances.
Here's a short clip of her that was probably featured in one of the old Hollywood gossip newsreels. It's easy to imagine this being read by a Jazz age "newsman":
Fashionably dressed Jazz Age actress and English countess Vera Cathcart poses for pictures after she is delayed from entering the United States on charges of "moral turpitude."
I've got it!
Drink a bathtub full of champagne to be in the mood for Lady Cathcart.
and the 1926 version of "feathered hair" indicates she may have been a trendsetter. Can't imagine how many magnums of champagne it would take to fill a bathtub but I'm hoping a Shorpy commenter will give us the details on that scandalous story.
[That "feathered hair" is a feather. - Dave]


text:
Web Code:
Customer Service |
Track Order |
Request a Quote |
Corporate Accounts
Home > At Work Compact L-Desk with Mobile Pedestal and Bookcase Set
NBF Signature Series
View Collection:
At Work
Item No:
60"W x 60"D Reversible Compact L-Desk has clean, uncluttered lines and bold contrasts to deliver a modern look to your office that suggests both style and function. Designed by NBF as part of the NBF Signature Series, the At Work Collection features a "floating" Espresso laminate top over a brushed nickel frame. Separate your office with this exclusive line you won't find anywhere else.
All-steel construction is spot-welded for strength and durability. Tough, 3/4" laminate surfaces resist scratches and stains. Rounded corners on top surfaces protect clothing and arms. L-Desk is fully reversible; attach return to either the right or left side of the desk. Mobile pedestal complements perfectly the table desks with Espresso laminate top surfaces and brushed nickel frames. At only 27"H, it fits nicely under the matching table desks. Pedestal drawers lock. File drawer accommodates letter size files. Bookcase has three shelves, two are adjustable. Three grommet holes and cable clips provide easy cable management.
Assembly required.
This item is a GSA Schedule Contract item. National Business Furniture's GSA contract number is: GS-27F-0024V.
For more information, please call one of our government specialists at 800-558-1010, or visit this page to learn about all our government contracts including Navy BPA, Air Force BPA, TXMAS and CMAS.
For a limited time, take an additional 15% OFF the price of this item by entering promo code HARVEST during checkout! Your discounted price will be reflected at checkout. Promotion valid for 15% off all qualifying products (excluding tax and shipping) using promo code HARVEST only. Qualifying products will be marked with a 15% Off tag. Promo code cannot be used with any other promotions or discounts and is limited to one use per customer. Promo code applies to merchandise only. Enter promo code on payment page in check out to see discount before submitting order. Promo code valid November 1, 2018 to November 30, 2018 11:59 p.m. CST.
Connect with us:
My Account
Track Your Order
Corporate Account
Customer Service
Request a Quote
Request a Catalog
Contact Us
Shipping Policies
About Us
Life at NBF
Join our Team
Furniture Consultants
Sustainability Statement
En Español
Privacy & Security
Site Map
Talk to one of our furniture specialists
Email Us
Web Code: ZXUP99-16734


text:
Best Earl Grey Ever!!!!
Jing Tea!!!!
Steve got me some Jing Tea for my birthday, which I have powered my way through. Its one of the best Earl Greys I have ever tasted so I highly recommend you try it if your a bit obsessed with tea!!!!
Goodbye!!! Untill next time!!!


text:
5820 Coldwater Road
Fort Wayne, IN 46825
(260) 483-9841
no known website (really? It's 2011 - welcome to the 21st century; coldwaterlanding.com is available at godaddy.com . . . jus' sayin')
Recently the 3 Elles dined at the Coldwater Landing. We arrived at 5:00 p.m. and found no hostess at the stand so we wondered into the bar where there were 3 patrons chatting with the bartender. There, we were immediately greeted and seated in a small room off the bar. The decorations and plates, including the fish in the fish tank, remain the same as they were when the restaurant was Chappell's (click here to see).
Initially, we were told there was no special martini or drink list - What?!?! After asking again, we were told the bartender had a little menu. Sherry, our server, brought back an impressive list of creative spirits including a full page of unique martini options. We all opened the evening with interesting choices:
For the first time ever in our nearly 3 years of 3 Elles outtings, our martinis were served unstrained . . . why is there ice floating in my milkshake martini (that won't bring the boys to the yard)? That was pretty disappointing - fortunately, we drank round one pretty quickly so the ice didn't have a chance to melt (much) - and the room where we were dining was pretty cold. You'll also notice that NONE of the above martinis were served with a garnish. That's the icing on the cake - it's the cherry on the sundae - it's the mint on the pillow. It's a small thing that makes a HUGE impact. Garnish is important!
I chose the Milkshake martini after Sherry had said several times how good it was. Who am I to go against the recommendations of the server? The menu said it was topped with whip cream and a cherry - not so much. It had a good flavor and was definitely interesting. We have not come across anything close to this uniqueness anywhere in Fort Wayne.
Allen L chose the Tropical Rain. This non-alcoholic alcohol martini was simply orange juice with some coconut. It's taste was deliciously light and refreshing, but it's benefit as an after work cocktail was non-existent.
Adams L chose the Banana Split. The pretty pink liquid dessert was good, but not extraordinary. It was playful combination of the traditional dessert flavors, but not worth making a special trip to this establishment to try. Swing through Dairy Queen for a more satisfying treat.
Round 2 centered around one drink - the special - a chocolate caramel truffle - YUM! The thick caramel drizzle on the glass was a super treat. This would make a fantastic dessert (not so excellent paired with my Caesar salad and fish).
The appetizer list was nearly 1/4 of their menu featuring oddities. Alligator tail and mussels and the like. Commonalities like bruschetta and artichoke dip aren't served here. Adams L did order the one thing we typically select, crab cakes (sorry no photo). The 2 little cakes were served beautifully atop 3 sauces drizzled on the plate. Although the small cakes lacked jumbo lump meat, they were simply the MOST delicious crab cakes I have ever eaten! These simply move to the top of the 3 Elles crab cake list of fame!!!!! The cakes were packed with big flavors and complimented wonderfully with the various sauces (a garlic aioli, and 2 spicy varieties). The Elles would have liked to see either 3 cakes or 2 larger ones. The portion size was disappointing. Exactly how good are these crab cakes? Allen L who never liked crab cakes before the Elles started going out, and usually can take them or leave them, said "These are so good that I could eat this for my meal!" Yeah - that's how good they were!
Our entrees came with a choice of house or Caesar salad. Adams L and Allen L chose the house salad (one with the dressing on the side). They found the limited number of choices for their dressing a bit disappointing, but found the house dressing fair with a woody taste. They agreed their husbands would hate the dressing. They felt it was crispy and cut nicely. It was presented beautifully.
I selected the Caesar salad. It was beautiful with its shaved parm cheese and large croutons (made from their dinner bread). Although it could have been fantastic, it was DROWNING in dressing which unfortunately ruined the salad. I would definitely get this salad again . . . with the dressing on the side!
Sorry for no photo, so you'll have to take our word for it. Delicious! Fresh from the oven, the 2 types of bread are served hot! A fantastic pairing with the salads and entrees. It's simplicity was it's strength. It might have been nice had it been served with olive oil and parm cheese or butter warm enough to spread, but that's simply our suggestion.
This was definitely the highlight of our visit. The food was beyond excellent. Although the menu does not contain great depth, what they do serve is simply sensational! Each of us completely enjoyed our entrees.
Adams L selected one of the evening's specials - a Teriyaki Sirloin with Shitaki Mushrooms paired with broccoli and asparagus atop a bed of wild rice. She said the sauce was flavorful and delicious. The steak was tender and well prepared, but could have been even better had the steak been marinated in the sauce rather than just drizzled with it prior to serving. The steak was so tender it could be cut with a fork. The vegetables and rice pairings completed this meal perfectly.
Allen L chose White Gulf Shrimp with Almond Herb Breading - the photo is worth 1000 words, look at them. They were HUGE and delicious. The flakey breading was not greasy in the least. The number of "MMMMMMMMMM's" coming from her side of the table tells the whole story. The twice baked potato was creamy and full of flavor variety. The pepper seasoned asparagus was crispy, not mushy just tender enough to be perfect!
I selected the Canadian Walleye served with 2 sides (twice baked potato and broccoli). The breading on the walleye was the same as the gulf shrimp (above) and was the best coating I have ever eaten! It was crispy but not greasy. It stayed on the fish and were able to be enjoyed in a single sensational bite. The broccoli was very delicious, but if you don't like pepper, I would definitely suggest telling them to either skip it or go light - a little went a long way. The twice baked potato may not be the best pairing with walleye, but it was definitely smooth and filling.
The other Elles selected a cheesecake drizzled with raspberry sauce. They commented about how homemade it tasted (though, it wasn't). They raved about how it wasn't too sweet and how it was so smooth. This was definitely a favorite for them. They felt the raspberry sauce was perfect to provide the hint of tartness. The girls really enjoyed this dessert and would definitely get it again.
I selected the homemade Chef's special Chocolate Pie with a praline crust. It was quite different than other desserts and I was glad that I selected it. The other Elles didn't care for it nearly as much as I did. The burnt cookie tasting crust paired with the over-the-top sweetness of the homemade fudge tasting top. It was very rich and was easily shared among the 3 of us. I loved that an eatery still creates their own desserts - classy!
Our server, Sherry, was attentive and prompt. Our water glasses were never empty - a huge plus for us! Our every question and request was attended to.
Given our good experience, I could see the 3 Elles returning to this restaurant.


text:
Sold for $234,000 on Jan 16, 2018
UNRIVALED QUALITY! Walk into this 4 BD, 2.25 Bath home featuring eyebrow windows with a welcoming wink. High ceilings add grandness to a split floor plan, LR w/ FPL & FDR w/ LG bay window. Unique tilework throughout this 2016 (+/-) home, central vac, RO, water softener, luxury master bath w/ his/her walk-in closets. KIT features breakfast bar, bright dining area, pantry, oak pullout cabinets, side by side SS fridge & appliances. Desert front & rear yards, 3 car Garage & Lrg covered patio. A true gem!


text:
- List your car for FREE - Advertise your car in both Unique Cars magazine and online
- Manage unlimited online ads with TraderAds - Call us today to discuss how we can help you sell more stock
It was the final Falcon that a passionate group of FPV engineers always wanted to build+MORE
Over 80 lots on offer+MORE
So, you fancy a new set of wheels? +MORE
Search car clubs here
View events in your state
Trade Safely. Use our anti-scam guide to protect yourself.
Sorry, map view is not available right now. Please search by seller location to enable map view.
We are delighted to offer this exceptionally rare Humber Pullman Laundaulette onto the market. There are only a handful of this type still in existence. The car was despatched from the factory on the 19th October 1931 to Rossleigh, Edinburgh. Documentation in the history from a Humber motoring Historian states the car is actually a 1932 model and is believed to have left the factory in its current colours of Royal Blue over Black. The Humber spent most of its life in Scotland, spending 50 years with the same family. The Humber also comes with its original Hackney Carriage 8 seats plaque as it was used to transport holiday guests from Granton Station to Aviemore Resort in Scotland. Having spent its entire life in Scotland, the most recent owner in Enfield bought the Humber in 1999 and has covered 6500 miles in the car over the past 18 years and the Humber arrives with us in impressive mechanical order, beautifully presented body and a totally original, unrestored interior.
The item you are attemping to add to compare is a different subtype to the items(s) in your list.
Only items of the same subtype may be compared.


text:
Bruichladdich Islay Barley 2006 Dunlossit Farm
Posted by Tom
Another cracker from Bruichladdich, this time the Bruichladdich Islay Barley 2006 Dunlossit Farm.
With exacting knowledge of where the barley has come from this makes it a very interesting dram and one i was excited to try.
Get your own bottle from Royal Mile Whiskies and try it for yourself
very sweet but natural not a refined sugary sweetness, more sweet plums and nectarines winey on the nose with manuka honey goodness
again very sweet more manuka honey, this time with added malted biscuits and some youthful wood notes
just right, a lovely, in fact amazing, dram
Bottle Name: Bruichladdich Islay Barley 2006 Dunlossit Farm
Age: 6
Distiller: Bruichladdich
Bottler: Bruichladdich
Type: Single Malt
From: Scotland, Islay
Related Articles
Bruichladdichs Islay Barley Series
Bruichladdich Islay Barley 2007 (Rockside Farm)
Bruichladdich Tweet Tasting
Octomore 7.3
Whisky Fringe 2012 Arrives


text:
The African buffalo, buffalo or Cape buffalo (Syncerus caffer) is a large African bovine. Owing to its unpredictable nature which makes it highly dangerous to humans, it has not been domesticated, unlike its Asian counterpart, the domestic Asian water buffalo.
No other game animal is held in higher esteem as a worthy hunting adversary than the African buffalo. The sheer thrill of hunting this mountain of muscle and attitude is unrivalled and addictive. The African buffalo is a very robust species. It is up to 1.7 metres high, 3.4 meters long. Savannah type buffaloes weigh 500–900 kg, with males, normally larger than females, reaching the upper weight. Buffalo have black or dark brown coats and their horns are curved to a closed crescent. Known as one of the "big five" or "Black Death" in Africa, the African buffalo is widely regarded as a very dangerous animal, as it gores and kills over 200 people every year. Buffalo are sometimes reported to kill more people in Africa than any other animal, although the same claim is also made of hippos and crocodiles. Buffalo are notorious among big game hunters as very dangerous animals, with wounded animals reported to ambush and attack pursuers.
Buffalo are herd animals concentrated on the open savannah where grazing and water is plentiful. They tend to graze from early evening into the night and then the cooler parts of the day, seeking shaded cover as it gets hotter. Both sexes have horns, with males developing the much desired gnarled bosses as they get older (many of the older hunters believe that the boss of a mature bull will stand up to the penetration capabilities of many heavy calibers). Despite their size, they are extremely well camouflaged in dense cover. Their eyesight and hearing is quite poor but their sense of smell is excellent. It is much harder to get close to a herd of buffalo than solitary bulls.
Buffalo are hunted on foot picking up and following fresh spoor at waterhole's or across roads. Older bulls tend to separate from the herds and are solitary or form small bachelor groups often called Kakulis or Dagga boys (meaning mud boys).
The best shot placement for buffalo is to hit vital organs, hopefully breaking bone somewhere in the process. Any experienced PH should advise to go for the "boiler room". If hit well, the animal will grunt at impact and take off at a gallop, usually signaling death with a characteristic bellow. Very few shots, regardless of caliber will pull a mature bull to the ground unless the shot hits the spine. If in a herd, the wounded animal usually breaks away and heads to thick cover. Buffalo are one of the only animals that will purposefully circle back onto their own trail to "hunt" and lie in wait for their pursuer. Usually they will circle back on their trail near and anthill, a fallen tree or any area that provides de
Buffalo are thick-skinned animals and the minimum safe caliber is the .375 Magnum. With Buffalo you can never have too much gun. I prefer the 416 remington or Rigby, 458 and of course the 470 and 500 double rifle. It is also advisable to load a soft-nosed round for the first shot, followed by solids as the animal moves off. Remember, you want to do as much damage as possible with your first shot and heavy grained, good quality soft-nosed bullets are essential.
I hunted a buffalo with a crossbow, when this was still allowed in South Africa. The arrow penertated well with the buff bleading vasts amounts of lung blood. Still this buffalo was followed for more than three hours charging us twice with me killing it at twenty yards with a 416. Buffalo have the ability to survive for longer even when taking out the vitals.
Trophy size judgment on buffalo is quite easy but remains an individual choice. Old bulls usually have worn horns with characteristic bosses.
A trophy needs to have a thick heavy wide boss, running outwards and downwards (the deeper the curl the better) well past the ears before curling upwards and back in again. The points then raise upwards and backwards, the higher the better. As a rule, the further past the ears the outer upward curl of the horns are, the better the trophy. Rowland Ward measurement is based upon the spread of the horns while SCI measures the total lengh plus both bosses.
Minimum RW score is 42"
Minimum SCI score is
Buffalo are fairly widespread throughout Africa, with the Cape or Southern Buffalo being the largest and most hunted. It is uncommon to hunt for buffalo and return home empty-handed unless you are hunting an area that has very few or no animals.
Buffalo can be hunted in most southern African countries with the most trophies taken in South Africa due to there intensive breeding projects where the genes can be selected and inbred. Buffalo often carry bovine tuberculosis , foot and mouth and other diseases which severely effects livestock. An imaginar red line is drawn south of which no infected buffalo are allowed. So if you are hunting a buffalo south of this line it means the animal has been through a quarantine process and is free of these diseases. These buffalo are all privately owned on private land. The hunt is very similar to hunting in darkest africa with a nearly 100% kill rate.
The Blue Wildebeest is a large antelope and one of two species of wildebeest.
Learn More
The Common Eland is considered, the largest species of "antelope".
The Greater Kudu is a woodland antelope found throughout eastern and southern Africa.
The lion is the second-largest living cat with some males weighing more than 550lb.
The African buffalo, buffalo or Cape buffalo (Syncerus caffer) is a large African bovine.
Learn More
The hippopotamus, or hippo, from the ancient Greek for "river horse"
The warthog is a wild member of the pig family that lives in Africa.


text:
Cre Recombinase (NEB #M0298) is a Type I topoisomerase from bacteriophage P1 that catalyzes the site-specific recombination of DNA between loxP sites (1). The loxP recognition element is a 34 base pair (bp) sequence comprised of two 13 bp inverted repeats flanking an 8 bp spacer region which confers directionality (3). Recombination products depend on the location and relative orientation of the loxP sites. Two DNA species containing single loxP sites will be fused. DNA between directly repeated loxP sites will be excised in circular form while DNA between opposing loxP sites will be inverted with respect to external sequences.
pLox2+ (linearized) (NEB #N0417) is a substrate for Cre Recombinase (NEB #M0298). It is 3.65 kb in length and has a loxP site approximately 350 bp from each end. Between the loxP sites lies an origin of replication and an ampicillin resistance gene. Recombination between these loxP sites by Cre Recombinase produces a circular, ampicillin-resistant plasmid (which migrates at approximately 1.7 kb on a 0.8% agarose gel) and an 850 bp DNA fragment.


text:
Morning Ritual is pleased to announce the release of HOLY STRAYS new single 'Christabell'.
HOLY STRAYS is the nom de plume of 22 year-old Paris-based musician and producer, Sebastien Forrester. The single, released on a limited edition 7" on transparent vinyl and digitally, follows on from his first releases via LA-based powerhouse Not Not Fun (Peaking Lights, Maria Minerva, Ducktails)
Christabell A & B, born here as non-identical twins, are formed from stuttery motorik drum patterns, twinkling synth micro-melodies and hypnotic organ loops whilst Forrester's own manipulated vocals spiral disembodied through the tracks under a haze of delay and reverb acting more as part of the music's instrumental make up then serving any lyrical function. The resulting soundscapes lie somewhere in between an ADHD take on Villalobos' percussive led experimental techno combined with the subtlety and playful instrumentation of Pantha du Prince overlaid with the otherworldly ethereal vocal styles of Balam Acab.
In the last year Holy Strays has remixed acts as diverse as Forest Swords, O F F Love and Loney Dear, and also sharing stages with various acts du jour such as Zola Jesus, Nite Jewell, Doldrums, Sun Araw and Laurel Halo.
Limited edition of 500 7" on Transparent Vinyl


text:
2 Ratings
Château de Musset Lalande de Pomerol
Wine Details
Wine Description
(2005 Vintage) It has a large wine selected for its intense purple dress for her elegant nose of ripe grapes, discreetly woody, and his dainty, soft and fresh both mouth footprint and liquorice fruit flavors and supported by tannins present but do not break the general harmony.
light. still young. Very good though. By itself


text:
How to remove "Advanced System Protector" Software
Last updated on November 24th, 2014
"Advanced System Protector" (by "Systweak.com") is a anti-spyware program that finds and removes malware infections from computers. "Advanced System Protector" is a LEGITIMATE software and usually comes on a computer as a bundled software inside other free programs that the user wants to install on its computer. Upon installed Advanced System Protector, performs a system scan and then demands from the computer user to buy the program in order to remove the malicious items found.
Some users complain that once "Advanced System Protector" is installed on their computers, they cannot terminate the program, their computer speed is decreased and and they cannot remove the program from their computer using Add/Remove Programs feature from control panel. This tutorial is written to help users to completely uninstall/remove the "Advanced System Protector" utility from their computers if they don't want to pay in order to use it.
Note: You must always pay attention when you install software on your computer.
If you want to completely remove Advanced System Protector from your computer, use the steps below:
How to remove "Advanced System Protector" from your computer:
Step 1. Start your computer in Safe Mode
As Advanced System Protector removal process –sometimes- is difficult to be performed, while running in normal Windows mode, it is better to reboot your computer and to log on to Windows using "Safe Mode with Networking" option.
1. To get into Windows Safe mode, press the "F8" key as your computer is booting up (before the appearance of the Windows logo).
2. When the "Windows Advanced Options Menu" appears on your screen, use your keyboard arrows keys to move to the "Safe Mode" option and then press "ENTER".
Step 2. Uninstall "Systweak" software from your Windows Control panel.
1. To do this, go to:
- Windows 8/7/Vista: Start > Control Panel.
- Windows XP: Start > Settings > Control Panel
2. Double click to open
- Add or Remove Programs if you have Windows XP
- Programs and Features if you have Windows 8, 7 or Vista.
3. In the program list, find and Remove (Uninstall) the following applications:
- Advanced System Protector (Systweak Software)
- RegClean Pro (Systweak Inc)
- MyPC Backup
- Any other application from "SysTweak" publisher.
Step 2. Manually delete remaining "Advanced System Protector" files/folders.
1. Open Windows explorer and navigate to "C:\Program Files" folder.
2. Delete all the folders listed below, if they exist:
- Advanced System Protector
- RegClean Pro
- MyPC Backup
- Any other application from "SysTweak" publisher.
2. Restart your computer and continue to Step 3.
Step 3. Clean your computer with MalwareBytes Antimalware.
Download and install one of the most reliable FREE anti malware programs today to clean your computer from remaining malicious threats. If you want to stay constantly protected from malware threats, existing and future ones, we recommend that you install Malwarebytes Anti-Malware PRO:
Malwarebytes™ Protection
Removes Spyware, Adware & Malware.
Start Your Free Download Now!
*If you don't know how to install and use "MalwareBytes Anti-Malware", read these instructions.
Advice: To ensure your computer is clean and safe, perform a Malwarebytes' Anti-Malware full scan in windows "Safe mode".*
*To get into Windows Safe mode, press the "F8" key as your computer is booting up, before the appearance of the Windows logo. When the "Windows Advanced Options Menu" appears on your screen, use your keyboard arrows keys to move to the Safe Mode option and then press "ENTER".
Step 4. Clean unwanted files and entries.
Use "CCleaner" program and proceed to clean your system from temporary internet files and invalid registry entries.*
*If you don't know how to install and use "CCleaner", read these instructions.


text:
For golfers, a strong core is essential. But if you hate sit-ups, the Ab Coaster is a good alternative in your quest for better golf fitness.
If you're like most people, you hate sit-ups. I have to find a couch or chair to anchor my feet and about a minute or two into it, my neck starts hurting, and I'm trying to reposition my feet so I don't have to rock to do the exercise.
Besides, no matter how dedicated I am when I start out, my commitment to doing daily sit-ups never seems to last more than a week or so.
There has to be a better way, right? (How many times have you heard that?)
Well, you could try the "as-seen-on-TV" Ab Coaster, which retails at $399 and seems to have more merit than some other abdominal exercise devices.
The Ab Coaster comes from the same guy who invented the successful Ab Roller. Don Brown, the inventor of the Ab Coaster and the president of Ab Coaster LLC, said about three years ago Dallas inventor Rob Nelson contacted him for some help on a product he was developing called the "Ab Razor."
"His idea was to pull your knees up an incline by holding on with your arms," Brown said. "I loved his concept and started to work with him on improving the design so it would isolate the abs from the bottom up, working lower, mid and upper abdominal area all at the same time. This involved adding a curved track, swivel seat and weight resistance."
Fourteen months later, the Ab Coaster was born, and the rest, including the often-run infomercial, is history.
The Ab Coaster: Setup and how it works
Getting everything out of the box was probably the hardest part, but once I had everything laid out, it probably took less than a half hour to assemble the Ab Coaster.
The machine basically consists of a curved track with a pad for your elbows up top and a padded seat for your shins that runs along the track. To operate it, you rest your elbows on the top pads while holding onto two grips and rest you shins on the pad below with your feet pointing downward.
Each exercise basically consists of pulling your knees and the seat toward your upper torso as the shin rest runs along the curved track. There are both fixed and swivel positions of the seat to target different abdominal muscle groups, including the obliques.
The machine also comes with two DVDs, one of which is "Core Express Workout." This video, which is about 25 minutes long, is probably 75 percent aerobics and strength training with lots of squats and stretches. About every five minutes or so, you are directed to the Ab Coaster to get in a few sets of crunches.
Each session on the Ab Coaster is slightly different, some of them using the locked position and some using the swivel feature. The latter is used for a maneuver called the "Mermaid," in which you make a fish tail movement with your lower body during the exercise.
The verdict on the Ab Coaster
Like all pieces of exercise equipment, the AbCoaster comes with some "ifs." If you are looking to lose weight, the AbCoaster will be of little help if you do not significantly change a poor diet, especially in terms of calorie intake.
Therefore, the Ab Coaster also comes with a diet plan, which if followed, will greatly increase your results.
"Diet is a critical piece of the puzzle," said Sean Gagnon, vice president of Ab Coaster LLC and exercise physiologist. "In fact, most studies show that the best results from an exercise program are achieved by those that combine a proper exercise routine with a sensible eating program as opposed to only one or the other."
It's also important to note that the consensus among nutritionists and exercise physiologists is that you can't spot reduce, meaning no matter how many reps you do on the Ab Coaster or any other piece of equipment, you will not have great looking abs unless you get rid of the overlying fat on top of them. And that can only occur if you create a calorie deficit (burn more calories than you take in) over time.
With that said, strengthening the core can never be a bad move, especially in golf, and if you use this machine regularly, you will be successful.
When I got the machine, I didn't go overboard, I merely followed the Express Workout DVD for two weeks. I didn't lose any weight (I wasn't exactly strict about my diet) or make any great distance gains in that time, but I did feel like it was easier to make a turn and get through the ball. By strengthening the core, my back also felt stronger, which for golfers is always a plus.
I also liked that I was in an upright position while doing the exercises, which means you can get in a thousand or so crunches if you wanted to and not miss a play on TV.
You can't do that with sit-ups. Every time you lie prone, you could be missing an Albert Pujols grand slam or a Peyton Manning-to-Dallas Clark TD pass. With the Ab Coaster, you could even watch Kenny Perry blow it down the stretch at the Masters and still work your abs without commercial interruption.


text:
Publisher: Entangled Teen
Release Date: September 1, 2015
Genre: Science Fiction
Source: Publisher for Review
Edition: eARC
Meet Morgan Dey, one of the top Reducers at The Body Institute.
Thanks to cutting-edge technology, Morgan can temporarily take over another girl's body, get her in shape, and then return to her own body-leaving her client summer, more toned, and feeling great. Only there are a few catches...
For one, Morgan won't remember what happens in her "Loaner" body. Once she's done, she won't recall walks with her new friend Matt, conversations with the super-cute Reducer she's been text-flirting with, or the uneasy feeling she has that the director of The Body Institute is hiding something. Still, it's all worth it in the name of science. Until the glitches start...
Suddenly, residual memories from her Loaner are cropping up in Morgan's mind. She's feeling less like herself and more like someone else. And when protests from an anti-Body Institute organization threaten her safety, she'll have to decide if being a Reducer is worth the cost of her body and soul....
**Thanks to Entangled Teen for allowing me to read this in exchange for an honest review!**
The Body Institute was an eerie science fiction novel that I completely ate up! It follows Morgan, who works for this place called The Body Institute. Basically, people can loan out their bodies for someone called a reducer to tone up and make slimmer. It's a way to keep obesity down, so many people donate their bodies to do this, especially because people in this society are taxed for being overweight. There are also random weigh-ins at school and such, which could be pretty scary, especially if you didn't work out the day before and you snacked on tons of ice cream instead.
Morgan is a reducer, so she helps slim down other people's bodies in exchange for lots of credits in order to help out her family and her grandfather. However, when Morgan goes to do her second reducer job, she's told by quite a few people not to. Perhaps she should've listened!
I was on the edge of my seat for a lot of this story, especially because of how incredibly unique it was. I absolutely ate up this world; it was kind of creepy but extremely interesting! I really adored Morgan as well, and I loved how badly she wanted to help out her family, no matter the cause. Matt was such an awesome supporting character. He was so geeky and sweet, and I loved him to bits. I also like how he and Morgan were always there for each other.
I did feel that the ending was a bit rushed; I feel like the story could've gone on for a bit longer but then again science fiction novels tend to be a little fast-paced towards the end. Plus, I still want to know more about what happened! With that being said, I'd love to read anything else that Carol Riggs writes in the future, especially if she has more amazing ideas like the idea behind this wonderful story.


text:
Level 2 courses
Bach Centre-approved Level 2 courses are the next step for participants who have completed an approved Level 1 course.
Level 2 gives you the opportunity to acquire confidence in choosing the right remedies for yourself and others and gain a deeper understanding of the remedies.
Topics covered include type and mood remedies and subtle differences between remedy pairs. You will also deepen your knowledge of Dr Bach's philosophy and explore how it might enrich your own approach to life.
Below we introduce the different types of approved Level 2 course. Certification in all cases is to the same standard, and once you have completed any of these courses you can move on to any approved Level 3 practitioner course.
Students on approved courses are eligible to apply for student registration with the Bach Centre, which can enhance your learning experience.
Bach Centre courses
The Centre's own Level 2 is a two-day course held at Dr Bach's home in Oxfordshire, England, in our purpose-built training rooms.
The course is led by an experienced Level 2 trainer and you will have the chance to experience life at Mount Vernon and enjoy the house and garden. Apply online now...
"The course is perfect. Richness and simplicity at its best."
BIEP courses
The Bach International Education Programme (BIEP) is the biggest international provider of Bach Centre-approved training, with courses in more than 30 different countries. More...
Independent approved courses
In some countries the Bach Centre approves courses run by independent teachers or small organisations. More...
Special courses for homoeopaths
Homoeopaths and student homoeopaths in the UK can attend a three-day course in London which takes participants to Level 2 standard. More...