text:
Armani JuniorBabymelBabymoovBella TunnoBugabooBurberryFreshly PickedGucciHerschel Supply Co.Itzy RitzyJoolzJu-Ju-Bekate spade new yorkLässiglittle unicornmimaMonclernunaOh Baby BagsPacaPodPetunia Pickle BottomProduct of the NorthQuiksilverRebecca MinkoffROSIE POPESkip HopStella McCartney KidsStokkeStorksakTed Baker LondonThe Honest CompanyThuleTWELVElittleVersace https://i.pinimg.com/236x/0c/43/84/0c4384a6d82a905d76e845d053d27bd1.jpg
The bag is beautiful and i like its design and colors. For me its not as boring as other diaper bags out there. I love the tassel attached to zipper and it look so cute and make the bag look more good. One intresting thing is that you can change tge shape of the bag. You can make it a tote like shape or a rounded upper sides shape. 2 pockets on the front and 1 pocket on each side is great and enough for my likings. It comes with changing sheet as well that i dont like much. It have pockets ... read more Click to read full text of review titled "Great Quality".
One is a laptop bag that I liked and decided to turn into a diaper bag. It's about the same width and height, but it's only about 4" deep. It could use a few more pockets since it only has the one... the laptop compartment - I use it for diapers, wipes and changing pad. Everything else is in a jumbled heap in the main compartment. Eh, it works. Slightly annoying, but it works.
Seemingly the most common complaint about this bag is that the main zippered compartment is deep, narrow, and simply not big enough. On the plus side, the narrow compartment means that the Skip Hop Duo Signature isn't too bulky, as many other diaper bags bags we tested were. But it also means that you may end up stacking your stuff in the main compartment, and not having much room for extras.
I have a JJ Cole bag, it's about the perfect size... maybe a little big now that DS is getting older and doesn't require so much stuff. It's 17" wide x 13" tall x 6" deep. I gave that one to my mom so she has a diaper bag (she watches DS during the day). It worked, but I never really did like it. I don't really like the tote style bags. I think they're kinda awkward. https://i.pinimg.com/236x/0e/b1/e3/0eb1e3174f0cce27aa234a00156559c1--fossil-handbags-fossils.jpg
For the busy parent on the go, diaper bags can be a life saver. Packed with great features, as well as, stylish designer looks, today's bags make sure any parent or guardian is fully prepared for any emergency. No need to sacrifice style when taking out your little ones. Choose from hundreds of diaper, stroller and messenger bags available in numerous designs made by Kalencom, SKIP*HOP? & Diaper Dude?. Shop our large selection of baby diaper bags from buybuy Baby. From fashionable polka dots to solids, shop for cute diaper bags for boys and girls. https://i.pinimg.com/originals/f5/4f/6f/f54f6fa5b77231efd7c82ca9e6f0cdcc.jpg
This is an excellent backpack diaper bag, and one of the all-around highest-rated diaper bags you can find in the US! And there are some great reasons for that. It's an amazing diaper bag backpack that doesn't stand out as a diaper bag: no excessive patterns or colors that make it obvious, just a simple and stylish diaper bag available in black or heathered grey. And is has features galore: it can be carried with the top handle, as a backpack, and it includes strong built-in straps so you can hang it on the back of your stroller. There are so many pockets, 14 of them in total, there is bound to be one that's the perfect size for what you need to haul around! There is a very large insulated baby bottle exterior pocket on one side, pockets for little things like your phone and pacifiers, larger things like baby lotion and a stuffed animal, and there's an awesome baby wipe dispenser on the side. You won't realize how awesome that is until you fill it up and need to quickly grab a wipe while you're out. Just reach back and pull one out. Simple, and we are starting to wonder why all diaper bags don't have this awesome feature! One thing we were really surprised by is how deceptive the main compartment is: you think it's going to be small but then you open it up and realize it's actually really big. Big enough that we could fit in: The Spectra S2 breast pump and accessories, diaper rash ointment, the changing pad (it's included), burp cloths, disposable diapers (or cloth diapers), and an extra change of clothes. And there was still room to spare. We really liked how large and versatile this backpack diaper bag was in our testing. We also thought the zippers and fabric were high quality, and the fabric seemed to do a decent job repelling water. We didn't rest it in a puddle or anything, but we noticed that splashing it with water didn't get into the bag at all. So, it should be good to go in a rainstorm. It also came with a small diaper tote that's the perfect size to fit a diaper, a small tube of cream, and a couple wipes into; the perfect size for bringing to the changing table. So, overall this is an excellent diaper bag backpack that is versatile and highly functional. Only a couple of small drawbacks. First, there have been reports of quality control issues with this bag. We didn't have any issues, but some moms report ripping near zippers, or the insulated pocket coming apart at the seams. But we want to point out that this company is very responsive to their customers, and they will replace the bag if you have any issues! So that's reassuring. Second, the backpack straps and padding aren't the most comfortable in the world, but we were happy to strap it onto our stroller after our shoulders got sore. We found it online for around $60, which we think is a good price for all this functionality. Interested? You can check out the Bag Nation Diaper Bag Backpack here.
Want to babywear but still need to carry a diaper bag—is that even possible? Yes, it is. It's also safe and can be comfortable when done right. You just need a front carry baby carrier and a backpack style diaper bag. Put your carrier on first, then put your baby inside the carrier and finally put your backpack diaper bag on. When your child is bigger and you switch to a back carry position, you can also wear a backpack diaper bag on your front. It may not look the best, but it can work if you need it to.
One is a laptop bag that I liked and decided to turn into a diaper bag. It's about the same width and height, but it's only about 4" deep. It could use a few more pockets since it only has the one... the laptop compartment - I use it for diapers, wipes and changing pad. Everything else is in a jumbled heap in the main compartment. Eh, it works. Slightly annoying, but it works. https://i.pinimg.com/236x/7c/94/21/7c942165111b7a7fbf32f806ff809e4b.jpg
Comfortable to carry. We looked for padded straps, good balance, and a low weight. We took a skeptical eye toward bags that, when empty, weigh more than 2 pounds (we did make a few exceptions). Comfort is subjective, and we wanted to find options for people who find backpacks or messenger bags more comfortable than shoulder bags. Bonus points for bags that could be carried in multiple ways. https://i.pinimg.com/236x/c1/cc/0b/c1cc0bc7a6db74f4b7a3cfc4281bfd06.jpg


text:
Greg Johnson is a personal finance and frugal travel expert who leveraged his online business to quit his 9-5 job, spend more time with his family, and travel the world. With his wife Holly, Greg co-owns two websites – Club Thrifty and Travel Blue Book. The couple has also co-authored a book, Zero Down Your Debt: Reclaim Your Income and Build a Life You'll Love. Find him on Instagram, Facebook, and Twitter @ClubThrifty.
Instagram, also owned by Facebook, may use similar algorithms to determine the types of trending content appearing in a user's news feed or Explore tab in the Instagram app. Smaller businesses appear to have a better ability to trend on Instagram using viral content compared to Facebook, although publishers and individuals may begin to take the lead there as well.
Viral marketing or viral advertising is a business strategy that uses existing social networks to promote a product. Its name refers to how consumers spread information about a product with other people in their social networks, much in the same way that a virus spreads from one person to another.[1] It can be delivered by word of mouth or enhanced by the network effects of the Internet and mobile networks.[2]
The best way to take advantage of something like Airbnb is to have a separate property that sits vacant all the time. This way, you can just worry about keeping it clean and never have to worry about making sure you're out of there when guests want to show up. While that's not always the most cost-effective way (owning another property can be pricey), it's the best.
Apple maintains it's viral appeal, with the iPhone X through their launch of the "Selfies on iPhone X" campaign. The secret to this example of viral marketing (which has clocked up over millions views both online and offline) is very simple: a product so great that it turns people into fans of the brand all on its own. People love themselves. If they have the possibility of spreading this love digitally through selfies, it's almost a guaranteed win. The iPhone X's brilliant selfie feature spread virally through various media forms before apple repurposed the viral content into one masterpiece, the iPhone X selfies film. As one of the YouTube comments says, "It's the most beautiful thing I've ever seen"… This viral marketing through video has allowed Apple to spread key features such as their Portrait Lighting effects and their TrueDepth camera.

subset: commoncrawl


text:
|Tiny Leaders
|1v1 Commander
|Magic Duels
|Canadian Highlander
|Duel Commander
|Commander / EDH
Printings View all
|Magic 2014 (M14)
|Promo set for Gatherer (PSG)
Combos Browse all
Xathrid Necromancer
Creature — Human Wizard
Whenever Xathrid Necromancer or another Human creature you control dies, put a 2/2 black Zombie creature token onto the battlefield tapped.
Set Price Alerts
Recent Decks
Xathrid Necromancer Discussion
TheRoaringRegisaur on Sacrificial Humans [Dark Ascension]
2 months ago
I love this deck, I have a really similar [modern] deck Humans to Demons, but I focus more on amassing humans that sacrificing, however, I do include Westvale Abbey Flip for additional sac opportunities. Xathrid Necromancer and Athreos, God of Passage make losing creatures less painful. Both Thalia, Guardian of Thraben and Thalia, Heretic Cathar prove to be great humans to have in your sideboard.
I'd appreciate it if you checked out my deck. Thank ya, and I hope you find my suggestions helpful!
Ardval on I die, you die, we all die, bye bye!
3 months ago
I love the deck! I get that the 1 mana self sacking creatures paired with Athreos, God of Passage must be insane with the drain triggers (or 3 life to the face) but did you consider running the likes of Cartel Aristocrat Bloodsoaked Champion Lingering Souls in a more aristocrats style deck? Cartel Aristocrat your free sac outlet will constantly have protection in this deck, Bloodsoaked Champion has recursion so you can keep casting, if they take the athreos damage you can play him again, if they don't take the damage you guessed it you can play him again. Lingering Souls is just one of the best cards in modern for BW sac fodder, flyers and recursion.
Continuing this way does open you up to Xathrid Necromancer because of the humans but I've never found it to work out that well myself. Elenda, the Dusk Rose is another option to crank up the tokens by doing what you're doing anyway but I imagine Teysa is a better filler for that drop anyway.
Vizkopa Guildmage basically gives you pay three mana and double your drain, before you sack the board that would be devastating.
Another human with great synergy for the deck humanless or not is Qarsi Sadist
Tzefick on Athreos, God of Passage (Orzhov) JLK Inspired
4 months ago
Suggestions for "additions" (I'm not sure what you want to take out)
Also here is my list if you want some additional inspiration: https://tappedout.net/mtg-decks/shadowborn-apostles-demons-will-rise/
The list is outdated, casual, and just a rough remake of a list I had previously that I lost, but there might be something you've missed in there.
- Aven Shrine - Provides ridiculous lifegains even with just a small number of apostles in the yard.
- Xathrid Necromancer - (Rotlung Reanimator v. 2) - Tokens enters tapped, which is an issue, but it triggers off humans which hits slightly more targets than cleric. More of an aggressive inclusion rather than combo defensive tool.
- Angel of Glory's Rise - gets back all your Clerics for another run.
- Rally the Ancestors - You have Immortal Servitude , this is its buddy.
- Doom Whisperer - Razaketh, the Foulblooded does what this does better under normal circumstances. Haven't playtested this one but the general idea is to Surveil as many Clerics into the graveyard as possible until you hit a mass-resurrection-spell. Combines really well with aforementioned Aven Shrine by possibly finding and fueling the Shrine's condition, leading to mass lifegains, leading to more Surveil.
- No Rest for the Wicked - Haven't playtested this one either and possibly more a jank inclusion. The idea is to make sure you can get your Clerics back into hand if Athreos is not available or people are willing to pay. It's better to just have the mass resurrection spells before this.
I would probably pull out:
- Krav, the Unredeemed - He seems lackluster in the setup and you don't seem to create an abundance of tokens to really abuse his ability.
- Harvester of Souls - Would likely swap him out for a Grim Haruspex . While the Harvester triggers off of your opponent's creatures dying, you would need a Grave Pact effect in play to actually take advantage of that. The main portion of cards you get from this is from your own creatures. And I figure if you are able to search for a demon, the Harvester is not the prime target. At least when I've played he has been under performing. The Haruspex is easier to cast and is returned with both Rally the Ancestors and Angel of Glory's Rise . You can even find her with Recruiter of the Guard in case you've already found your Edgewalker .
- Unburial Rites - Just seems lackluster to me but that's also because my playgroup run a lot of exile, especially on big targets in colors that usually gets them back. In general I find Phyrexian Reclamation to be a better inclusion because I can secure I get my Clerics back which is the overall gameplan.
Anyway just my 2 cents. Hope you can use it in some capacity :)
ScryLord on Angry Necromancer
5 months ago
Falkenrath Aristocrat has some nice synergy with Xathrid Necromancer ... Perhaps you could consider that if you're not interested in Scab-Clan Berserker ...
Xynarth on Queen of the Orzhov [[Teysa Karlov Combo Build]]
5 months ago
I like the Quest, but it needs to be sacrificed after removing the three counters, sadly. There are a few sac weenies in white that would allow to fetch it back from the graveyard, but I don't know...
Instead, I'd put in something like Yahenni, Undying Partisan. Triggers with Teysa, has synergy through his sac indestructibility, and will eventually become quite monstrous (if that's the plan behind the 5/5).
Also considering you have 6-7 humans, maybe you could run Xathrid Necromancer. I know it's not really great, but still. Same for Disciple of Bolas to get some more card draw and Shadows of the Past is great value (I'd run either it or the Jar of Eyeballs that I mentioned before). Just remember that it's "Scry 1" twice and not "Scry 2" . People in my playgroup forget sometimes, hehe
I know these are a looooot of suggestions being thrown at you left and right, sorry about that. I'm just in a really big deck building/experimenting mood lately!
landofMordor on saj0219
6 months ago
Hey friend! First, that sounds like a good trade to me. My RiP is from RTR, and is NM/LP.
In addition, if your binder is up to date, I might be interested in Arlinn Kord Flip (is she SOI?) and some random Cube wants like Xathrid Necromancer, Shu Yun, the Silent Tempest, and Wayward Swordtooth if you wanted to trade some small fry. No worries if you're using those, but I figured I'd ask (:
AlexHeinrichs on Human Sacrifice (Need Help Improving!)
6 months ago
I remember playing something like this when I first got into magic back in Innistrad, so i think I can help you out.
I don't know how competitive you want to make this so i'll just try to improve the list based on your strategy and won't change the theme of the deck. First things first, let's trim your list a bit, you have a bunch of 2 and 3-ofs instead of playsets of the stuff you really want (4x Doomed Traveler, 4x Lingering Souls, 4x Demonic Taskmaster).
Second, I would cut the stuff that has synergy with the deck but don't really help you win the game (Unruly Mob, Thraben Doomsayer) and things that are way too expensive. Ravenous Demon Flip is sweet but not so much when you have 3 of them in your hand along with some Reaper from the Abyss. So I would cut reaper completely, cut Ravenous Demon Flip to 2 at most, and cut Increasing Devotion (5/10 mana is too much).
Now we start upgrading some things. For 1-drops, we just got a good one in guilds of ravnica for this style of deck in Hunted Witness, so I would definitely play that alongside Doomed Traveler. Demonlord of Ashmouth is really good in a deck like this, and he's the demon I would likely run instead of the 5 and 6 mana ones.
Lastly, we need interaction. Orzhov Charm is a good choice, you can use it as removal, to save one of your demons or bring back one of your 1-drops for extra fodder. Tragic Slip is a great removal option here, since you're saccing your own stuff all the time it's basically a 1 mana Murder. I probably wouldn't even play card draw in this deck, but if you want to play it go with Altar's Reap, its instant speed and can help trigger morbid for slip and high priest.
I know your manabase is super budget but i would highly recommend Caves of Koilos, it's dirt cheap and it's gonna help a ton.
I'd play something like this: 4 Hunted Witness, 4x Doomed Traveler, 3x Skirsdag High Priest, 4x Demonic Taskmaster, 2x Xathrid Necromancer, 4x Demonlord of Ashmouth 4x Gather the Townsfolk, 4x Lingering Souls, 4x Orzhov Charm, 4x Tragic Slip 7x Plains, 4x Scoured Barrens, 8x Swamp, 4x Caves of Koilos.
Combo: T1 Doomed Traveler (or Hunted Witness), T2 Skirsdag High Priest, T3 Demonic Taskmaster, T4 sac Doomed Traveler to Demonic Taskmaster to trigger morbid, tap the token, taskmaster and high priest to make a 5/5 demon!
That's it, i hope it helps!
StopShot on
8 months ago
Hmmm, seems like you might limit yourself if you stick to just humans. Also the only cards in your deck that care if you play humans is Xathrid Necromancer, Thalia's Lieutenant, Champion of the Parish, and Falkenrath Aristocrat which that last one you can't reanimate with your commander.
You're probably going to want loads more tribal support if you're dedicated to just humans. This deck badly wants Adaptive Automaton, Door of Destinies, Kindred Boon, Kindred Dominance, Mirror Entity, Obelisk of Urd, Path of Ancestry, Shared Animosity, Shared Triumph, Stoneforge Masterwork, Taurean Mauler, Unclaimed Territory, Urza's Incubator, Vanquisher's Banner, and Cavalry Pegasus.
Besides tribal support, your deck might like Path to Exile, Boros Signet, and Sinister Concoction.
Lastly, while this is a humans tribal deck there are some non-human creatures that can give effects to all creatures, which when you think about it can be treated as though it were a tribal ability in essence. These creatures would be Angel of Invention, Drana, Liberator of Malakir, and Grenzo, Havoc Raiser, because their effects also apply to all your human creatures.
Xathrid Necromancer occurrence in decks from the last year
Commander / EDH:
All decks: 0.01%


text:
CN106068103A - Porous nanocrystalline cellulose structures - Google PatentsPorous nanocrystalline cellulose structures Download PDF
- Publication number
- Authority
- China
- Prior art keywords
- coil
- vaso
- curved
- section
- winding
- Prior art date
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12031—Type of occlusion complete occlusion
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12154—Coils or wires having stretch limiting means
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00526—Methods of manufacturing
[0001] 本发明的技术领域总体上涉及用于在人类或动物患者的血管中植入用于形成栓塞或血管闭塞的血管闭塞装置。 [0001] Technical Field The present invention relates generally to a blood vessel in a human or animal patient implant for vascular occlusion or embolization of vascular occlusion devices. 更具体地,本发明涉及沿其长度制造了弯曲区段的血管闭塞线圈。 More particularly, the present invention relates to a vascular occlusive coil bent section along its length.
背景技术 Background technique
[0002] 可出于多种原因使用血管闭塞装置或植入物,包括治疗血管内动脉瘤。 [0002] can be used for a variety of reasons vaso-occlusive devices or implants, including treatment of vascular aneurysms. 常用的血管闭塞装置包括通过绕"主"心轴卷绕铂(或铂合金)线丝束或细丝而形成的柔软、绕成螺旋状的线圈。 Commonly used vaso-occlusive device comprises a flexible, helically wound coil formed by winding the "main" winding mandrel platinum (or platinum alloy) wire strands or filaments. 然后,将该线圈绕在更大的"二级"心轴上,并进行热处理以形成二级形状。 Then, the coil wound more "secondary" mandrel, and heat treated to form a secondary shape. 例如, 授予Ritchart(理查)等人的美国专利第4,994,069号描述了一种血管闭塞装置,其在为了穿过输送导管的内腔安置而伸展时呈线性螺旋形初级形状,而在从输送导管释放并存留在脉管系统内时呈折叠盘绕的二级形状。 For example, U.S. Patent No. 4,994,069 granted Ritchart (Richard) et al., Describes a vaso-occlusive device, which is linear helical primary shape when disposed through the lumen of the delivery catheter in order to stretch and, from the delivery catheter and in He was released and two remain folded shape when coiled within the vascular system. 也可利用点卷绕或"无心轴"方法形成卷绕线圈。 Winding coils may be formed using a wound site or "unintentional axis" method. 在无心轴线圈卷绕方法中,将线丝束或细丝卷绕到挠曲面上。 In the ring unmotivated axis winding method, the wire strands or filaments wound around the deflection surface.
[0003] 为了将血管闭塞装置输送到血管系统中所需的部位(例如,动脉瘤囊内),所熟知的是首先使用可操纵导丝将外形很小的输送导管或"微导管"放置在所述部位。 [0003] The vaso-occlusive device for delivery to the desired site of the vascular system (e.g., aneurysm sac), it is the first known use of a steerable guidewire or catheter small delivery profile "microcatheter" placed the site. 通常,由主治医师或制造商根据患者的特定解剖结构为微导管的远端提供选定的预成形弯曲,例如45°、26°、"J"形、"S"形或其它弯曲形状,以便一旦抽出导丝,微导管的远端将留在所需位置,以将一个或多个血管闭塞装置释放到动脉瘤中。 Typically, selected to provide the distal end of the microcatheter by the attending physician or the manufacturer of the particular patient's anatomy preformed bent, for example 45 °, 26 °, "J" shaped, "S" shape or other curved shape to Once the guide wire withdrawn, leaving the distal end of the microcatheter at a desired location, to one or more vaso-occlusive devices into the aneurysm released. 然后,使输送线丝或"推进器"线丝穿过微导管,直至耦合至输送线丝远端的血管闭塞装置从微导管的远端开口伸出并进入动脉瘤中。 Then, the conveying wire or "pusher" wire through the microcatheter until the distal end of the delivery wire is coupled to a vaso-occlusive device extending from the distal end opening of the micro catheter and into the aneurysm. 一旦血管闭塞装置处于动脉瘤中,血管闭塞装置便会变形或弯曲以允许充填。 Once the vaso-occlusive device in an aneurysm, vascular occlusion device will be deformed or bent to allow for filling. 然后,从端部输送线丝释放或"拆卸"血管闭塞装置,并经导管抽出输送线丝。 Then, from the end portion of the delivery wire release or "detached" vaso-occlusive device, and withdrawn through conduit delivery wire. 根据患者的特定需求, 可推动一个或多个附加闭塞装置穿过导管并在同一部位将其释放。 According to the specific needs of the patient, can push one or more additional occlusive device through the catheter and release it at the same site.
[0004] 从推进器线丝的端部释放血管闭塞装置的一种众所周知的方式是使用可电解分开的接合部,该接合部是沿推进器线丝的远端部分设置的很小的暴露区段或分离区。 [0004] One well known way to release vaso-occlusive device from the end of the pusher wire is to use a separate electrolysis engaging part along the distal portion of the pusher wire disposed small exposed region separation zone or section. 分离区通常由不锈钢制成,且位于紧邻血管闭塞装置的位置。 Separation zone is typically made of stainless steel, and is located immediately adjacent to the vaso-occlusive device. 可电解分开的接合部在推进器线丝在离子溶液(例如,血液或其它体液)存在的情况下带电时易于被电解和分裂。 Electrolytically separated electrolytic joint and split easily when the charging in the case where the pusher wire in ionic solutions (e.g., blood or other bodily fluids) is present. 因此,一旦分离区从导管远端离开并暴露于患者的血管血液池中,通过电触头施加在导电推进器线丝上的电流便形成带有返回电极的电解分离回路,并且分离区由于电解而分裂。 Thus, once the separation zone away from the distal end of the catheter and the blood vessel exposed to the pool of patients, by applying an electrical current to the conductive contact of the pusher wire will form an electrolytic circuit with a return electrode separation, due to the electrolysis and the separation zone and division.
[0005] 为了更好地框住并填充动脉瘤,所熟知的是使血管闭塞线圈形成复杂的三维二级形状。 [0005] For a better framing and fill the aneurysm, the blood vessel is known occlusive coil formed two complex three-dimensional shape. 然而,使线圈形成二级形状在输送期间会增大线圈施加于微导管内表面上的接触力。 However, the shape of the coil to form a secondary coil during delivery increases the contact force applied to the inner surface of the microcatheter. 该附加接触力会增大线圈与微导管之间的摩擦,妨碍线圈输送。 The additional contact force will increase friction between the coil and the microcatheter, impede the delivery of the coil. 已意识到的关于具有二级结构的血管闭塞线圈的另一个问题是线圈的远端部分离开微导管开口端之后远端部分会旋转。 Another problem with having a vaso-occlusive coil secondary structure has been appreciated that the distal end portion of the coil after leaving the open end of the microcatheter distal portion rotates. 这使得输送期间的定向变得复杂。 This makes the orientation of the delivery period becomes complicated.
[0006] 在血管闭塞线圈领域,二级形状以及线圈的刚度、柔韧性(flexibility,挠性)和柔软度会影响线圈在动脉瘤内自行形成框架并分布的能力。 [0006] In the field of vaso-occlusive coils, stiffness, flexibility, shape, and two coils (Flexibility, flexibility) and softness coils can affect the frame itself is formed within the aneurysm and distribution capacity. 已知了多种二级形状和刚度。 Various known shapes and two stiffness. 一个实例是具有初级主线圈(其具有扭曲三角形剖面)和盒状二级结构的线圈。 One example is having a primary main winding (which has a twisted triangular cross-section), and a coil box-like secondary structure. 初级线圈的扭曲三角形形状在使线圈沿三角形的边具有优先折叠区域的同时,限制了挠曲转变点的数量,这是因为线圈将抵抗在扭曲三角形的顶点处折叠(与扭曲三角形的边相比)。 Twisted triangular shape of the primary coil so that the coil along the triangle have a preferential folding area at the same time, limiting the number of transition points of flexure, because the coil resistance at the apex of the triangular folding twist (twist triangle sides compared ). 因此,需要一种具有这样的挠曲点的血管闭塞线圈,该挠曲点可位于初级线圈卷绕的很大部分的任意位置,而无需附加预设二级形状(或使二级形状最小化)。 Accordingly, a need for a vascular occlusive coil having such a deflection point, the inflection point can be located anywhere in the primary coil is wound a large proportion of, without additional two predetermined shape (a shape to minimize or to two ).
[0007] 根据本发明的一个实施方案,血管闭塞装置由一股细长材料形成,该细长材料通过卷绕过程卷绕成具有一段长度的螺旋线圈,其中线圈沿其长度的一区段或多区段在卷绕过程期间所经受的机械应力或应变小于线圈剩余部分所经受的应力或应变,这样使得一区段或多区段中的每一区段,相比于线圈剩余部分的相应刚度和柔韧性而言,具有较小的刚度和较大的柔韧性,且当将线圈输送入动脉瘤内时,一区段或多区段中的每一区段沿线圈长度充当弯曲位置。 [0007] According to an embodiment of the present invention, vascular occlusion device formed from an elongate material, the elongate material is wound into a helical coil having a length by winding process, wherein the coil along a portion of their length or multisession mechanical stress during the winding process is subjected to stress or strain or strain less than the remaining portion of the coil is subjected, such that each segment of a multi-zone, compared to the corresponding remaining part of the coil in terms of stiffness and flexibility, it has a smaller stiffness and greater flexibility, and when delivered into the coil within the aneurysm, the length of each segment along the coil in a multi-zone serving as bending position.
[0008] 举例来说,一区段或多区段线圈中的每一区段在卷绕过程期间所经受机械应力或应变可小于线圈其余部分的应力或应变,这可通过(i)在卷绕各个不连续线圈区段期间使施加于细长材料的张力暂时减小,和(ii)在卷绕各个不连续线圈区段期间使细长材料与其上卷绕有线圈的心轴形成的角度暂时增大而实现,或通过二者之一实现。 [0008] For example, a section of each sector or section of the coil during the winding process is subjected to mechanical stress or strain may be less than the rest of the coils of the stress or strain which can be obtained by (i) the volume the angle of the tension applied to the elongated material during the winding of each coil section is temporarily reduced discontinuously, and (ii) contacting each of the elongated material during winding successive coils without a coil wound thereon sections mandrel formed temporarily increase achieved, or achieved by either. 尽管已形成,但所得线圈的一个或多个"弯曲"区段的尺寸优选与线圈剩余部分的尺寸基本相同,至少无需使用任何视觉辅助可进行检测。 Despite it formed, but one or more coils of the resultant "curved" size of the remaining portion of the coil segment size is preferably substantially the same, at least an auxiliary can be detected without using any visual. 具体而言,线圈的一个或多个弯曲区段的绕圈优选具有与线圈剩余部分的绕圈基本相同的节距。 Specifically, one or more curved sections of the coil windings of the remaining portion preferably has a coil windings substantially the same pitch.
[0009] -个或多个弯曲区段可由沿线圈长度的单个弯曲区段组成,这尤其适用于相对较短的线圈。 [0009] - one or more curved segments by a single curved section along the coil length composition, which is particularly suitable for relatively short coils. 在其它实施方案中,一个或多个弯曲区段包括沿线圈长度的多个弯曲区段,弯曲区段的长度可基本一致或长度可不同,这适用于较长的线圈。 In other embodiments, one or more curved segments comprises a plurality of curved segments along the coil length, length of the curved section length may be substantially uniform or may be different, this applies to the longer coil. 各个非弯曲区段与弯曲区段之间的过渡可以是逐渐过渡或突然过渡(如本文所限定),或逐渐过渡与突然过渡结合。 Each non-curved section and the curved section of the transition between the transition may be gradual or abrupt transition (as defined herein), or a gradual transition in combination with an abrupt transition.
[0010] 根据本发明的另一个实施方案,血管闭塞装置由一股细长材料形成,该细长材料通过卷绕过程卷绕成螺旋线圈,线圈包括多个弯曲区段和多个非弯曲区段,其中各个弯曲区段与各个非弯曲区段沿线圈长度交替,且其中弯曲区段在卷绕过程期间所经受机械应力或应变小于非弯曲区段,这样使得,相比于非弯曲区段的相应刚度和柔韧性而言,弯曲区段具有较小的刚度和较大的柔韧性。 [0010] According to another embodiment of the present invention, vascular occlusion device formed from an elongate material, the elongate material is wound into a spiral coil by winding process, the coil comprising a plurality of curved segments and a plurality of non-curved region segments, curved segments wherein each curved section and the respective non alternately along the coil length, wherein the curved section and the mechanical stress during the winding process or is subjected to strain of less than a non-curved sections, so that, as compared to non-curved section the respective stiffness and flexibility, the curved section having a smaller stiffness and greater flexibility.
[0011] 举例来说,弯曲区段在卷绕过程期间所经受的机械应力或应变可小于非弯曲区段的应力或应变,这是由于(i)在卷绕每一个弯曲区段期间施加于细长材料的张力暂时减小, 和(ii)在卷绕每一个弯曲区段期间细长材料与其上卷绕有线圈的心轴形成的角度暂时增大,或由于二者之一。 [0011] For example, the curved section mechanical stress during the winding process or is subjected to stress or strain the strain may be less than the non-bending section, which is due to (i) during winding of each section is applied to a curved temporarily reducing the tension of the elongated material, the angle and (ii) during winding of each section of the curved elongated material thereon with a coil wound around a mandrel formed to temporarily increase, due to one or both. 尽管已形成,但弯曲区段的尺寸优选与非弯曲区段的尺寸基本相同, 具体而言,其中弯曲区段的绕圈具有与非弯曲区段的绕圈基本相同的节距。 Although formation, but the size and dimensions of the non-curved section is preferably curved segments are substantially the same, specifically, wherein the turns of the curved section having non-curved sections of the windings substantially the same pitch.
[0012] 在各个实施方案中,各个弯曲区段的长度可基本一致。 [0012] In various embodiments, the length of each bent segment may be substantially uniform. 在一些实施方案中,非弯曲区段的长度从线圈远端向线圈近端将减小。 In some embodiments, the length of the non-curved section will be reduced from the coil to the distal end of the proximal coil. 同样,各个非弯曲区段与弯曲区段之间的过渡可以是逐渐过渡或突然过渡,或逐渐过渡与突然过渡结合。 Similarly, the transition between the curved section and the respective non-curved section may be a gradual transition or abrupt transition, with a gradual transition, or an abrupt transition binding.
[0013] 结合附图,根据以下详细描述,本发明实施方案的其它和进一步特征将变得显而易见。 [0013] conjunction with the accompanying drawings, the following detailed description, other embodiments and features of a further embodiment of the present invention will become apparent.
[0014] 附图图示了本发明实施方案的设计和应用,其中相似元件以共同附图标记表示。 [0014] The drawings illustrate the design and application of an embodiment of the present invention, wherein like elements are represented by common reference numerals. 这些附图不一定按比例绘制。 The drawings are not necessarily drawn to scale. 为了更好地理解如何获得上述以及其它优点和目的,将更具体地描述附图中图示的实施方案。 To better understand how to achieve the above and other advantages and objects, embodiments illustrated in the drawings will be more specifically described. 这些附图仅描绘了典型实施方案。 These drawings depict only typical embodiments.
[0015] 图1是根据本发明的一个实施方案构造的血管闭塞装置的详细纵向剖视图。 [0015] FIG. 1 is a longitudinal cross-sectional view of a detailed embodiment of a vaso-occlusive device constructed embodiment of the present invention.
[0016] 图2是根据本发明的另一个实施方案构造的血管闭塞装置的侧视图。 [0016] FIG. 2 is a side view of a vaso-occlusive device constructed in accordance with another embodiment of the present invention.
[0017] 图3A至图3C是根据本发明的又一个实施方案构造的血管闭塞装置的当该血管闭塞装置从导管输送入基本封闭的空间(例如,动脉瘤)内时的详细纵向剖视图。 [0017] FIGS. 3A to 3C are cross-sectional view showing a detailed longitudinal vaso-occlusive device configuration as that when the vaso-occlusive device delivery from the catheter into a substantially enclosed space (e.g., aneurysm) in accordance with a further embodiment of the present invention.
[0018] 图4和图5是根据本发明的一个实施方案的正在卷绕的血管闭塞线圈的示意图。 [0018] FIG. 4 and FIG. 5 is a schematic diagram according to one embodiment of the present invention is being wound vaso-occlusive coil.
[0019] 图6A和图6B是根据本发明的各个实施方案的两个卷绕血管闭塞线圈的侧视图。 [0019] 6B is a side view of the two vasoocclusive coil wound various embodiments of the present invention according to FIGS. 6A and FIG. 线圈一部分支撑在上表面上,一部分悬挂在下表面上方。 The coil portion is supported on the upper surface, the lower surface of the upper portion of the suspension.
[0020] 图7是处于自然状态模式的闭塞线圈的立体图,图示了根据本发明的实施方案的一个示例性第二构造。 [0020] FIG. 7 is a perspective view of the occlusive coil natural state pattern, illustrating a second exemplary configuration according to an embodiment of the present invention.
具体实施方式 Detailed ways
[0021] 对于以下所定义的术语,除非权利要求或本说明书的其它地方给出不同定义,否则应采用这些定义。 [0021] For the following defined terms, unless the claims or elsewhere in this specification are given different definitions, these definitions shall be used otherwise.
[0022] 无论是否明确指示,本文中的所有数值均被认为是由术语"大约"修饰。 [0022] Whether or not explicitly indicated, all numbers in this article are considered by the term "about". 术语"大约"通常是指人们视为与所述值等价的数值范围(即,具有相同的功能或结果)。 The term "about" refers generally seen as a range of the numerical value equivalent to (i.e., having the same function or result). 在许多实例中,术语"大约"可包括被四舍五入至最接近的有效数字的数值。 In many instances, the term "about" may include the values are rounded to the nearest significant figure.
[0023] 由端点表示的数值范围包括落入该范围内的所有数值(例如,1至5包括1、1.5、2、 2·75、3、3·80、4和5)。 [0023] The recitation of numerical ranges by endpoints include all numbers falling within (e.g., 1 to 5 includes 1, 1.5, 2 and 5 · 80,4 75,3,3 *) within this range.
[0024] 除非上下文另有明确说明,否则如本说明书和所附权利要求中所使用,单数形式"一"、"一个"和"该"包括复数形式。 [0024] Unless the context clearly indicates otherwise, as in this specification and the appended claims, the singular forms "a", "an" and "the" include plural forms. 除非上下文另有明确说明,否则如本说明书和所附权利要求中所使用,术语"或"的含义通常包括"和/或"。 Unless the context clearly indicates otherwise, as in this specification and the appended claims, the term meaning "or" typically includes "and / or." 如本说明书和所附权利要求中所使用, 术语"股(strand)"包括但不限于术语"线丝(wire)"、"细丝(filament,丝体)"、"纤维"等。 As used in the claims of the present specification and the appended claims, the term "unit (Strand)" includes but is not limited to the term "wire (Wire)", "filament (filament, filament)", "fiber" and the like. 如本说明书和所附权利要求中所使用,术语"尺寸"包括但不限于股厚度、线圈外直径、线圈内腔内直径和线圈卷绕节距。 As used in this specification and the appended claims, the term "size" includes but is not limited to the thickness of the shares, the outer diameter of the coil, the inner coil lumen diameter and winding pitch of the coil. 如本说明书和所附权利要求中所用,短语"线圈的突然变化" 及其等同表达是指线圈的1至3个绕圈发生的变化。 As used in this specification and the appended claims, the phrase "an abrupt change of the coil" refers to a change in the expression of their equivalents 1-3 turns of the coil occurs. 如本说明书和所附权利要求中所用,短语"线圈的逐渐变化"及其等同表达是指线圈的4个绕圈至整个线圈区段长度发生的变化。 As used in this specification and the appended claims, the phrase "gradual change of the coil" refers to a change in the expression of their equivalents four coil windings to the entire length of the coil section occurs.
[0025] 以下参考附图对各种实施方案进行描述。 [0025] below with reference to the accompanying drawings of various embodiments will be described. 应注意,附图未按比例绘制,且在所有附图中,结构或功能相似的元件以同样附图标记表示。 It should be noted, drawn not to scale drawings, and the drawings, configuration, or functionally similar elements are denoted by like reference numerals. 还应注意,附图仅用于帮助描述实施方案。 It should also be noted that the figures only for help described embodiment. 这些实施方案并非用于穷尽地描述本发明,本发明仅由所附权利要求及其等同物限定。 These embodiments are not exhaustive of the present invention for describing the present invention is limited only by the appended claims and their equivalents.
[0026] 本公开描述了用于制造螺旋状卷绕的线圈的方法,包括修改初级和二级卷绕参数,例如细丝张力、细丝角度和心轴张力,以生产沿其长度交替具有较硬和较软的区段的初级卷绕线圈。 [0026] The present disclosure describes a method for manufacturing a spirally wound coil including primary and secondary winding modifying parameters such as tension filament, and the filament angle of the tension mandrel, to produce alternating along its length has a more hard and soft segments of the primary winding of the coil. 具体而言,根据描述的过程生产的线圈的区段沿其长度在刚度、柔韧性和/或柔软度上可有所不同,而线圈整个长度的尺寸基本相似,即使得肉眼看不到差别。 Specifically, according to the procedure described in the section of production of the coil along its length in the stiffness, flexibility and / or softness may vary, the size of the overall length of the coil is substantially similar, even if invisible to obtain the difference. 具体而言,沿线圈长度散布的柔韧性大于(刚度小于)线圈剩余部分的较软周期性区段构造成在线圈上形成弯曲/挠曲点以更好地框住和/或填充动脉瘤,而无需进一步使初级卷绕线圈形成任何二级形状。 Specifically, scattered along the coil length is greater than the flexibility (stiffness less than) the remaining portion of the soft segment periodically configured to form a coil bending / deflection point on the coil to better framing and / or fill the aneurysm, without further winding the primary coil forming any secondary shape. 在一些实施方案中,理想的是仍使远端形成一些二级形状特征(例如预设形状,例如"J"形或45度的角度)以使线圈更指向中心,并使线圈近端形成螺旋状环("猪尾巴")以帮助防止线圈尾部从动脉瘤延伸入载瘤动脉内。 In some embodiments, it is desirable that the distal end is formed still features a number of two shapes (e.g. a preset shape, such as a "J" or angle of 45 degrees) so that the coil more toward the center, and a spiral coil forming a proximal end ring-shaped ( "pig tail") to help prevent the coil tail portion extending into the aneurysm from the aneurysm.
[0027] 图1图示了根据一个实施方案的血管闭塞装置10。 [0027] FIG 1 illustrates an embodiment of a vascular occlusion device 10. 血管闭塞装置10由已卷绕成具有一段长度的螺旋状初级线圈的单个细丝16形成。 The vaso-occlusive device 10 is spirally wound a primary coil having a length of a single filament 16 is formed. 血管闭塞线圈10沿其长度交替具有较硬区段12和较软(或"弯曲")区段14,各个较硬区段12和较软区段14的每一个均包括多个线圈绕圈。 Vaso-occlusive coil 10 having alternating softer and harder segments 12 (or "bent") sections 14, each section 12 and a softer hard segments each comprising a plurality of coils 14 are windings along its length.
[0028] 细丝16由任何合适的生物相容性材料制成。 [0028] The filament 16 is made of any suitable biocompatible material. 例如,细丝16可由金属,例如纯铂制成。 For example, the filaments 16 may be formed of metal, such as pure platinum. 在其它实施方案中,细丝16可由合金制成,例如铂钨合金,例如8%钨和其余的铂。 In other embodiments, the filaments 16 may be made of alloys such as platinum-tungsten alloy, eg, 8% tungsten and the remainder platinum. 在进一步的实施方案中,细丝16可由铂铱合金、铂铼合金或铂钯合金制成。 In a further embodiment, the filaments 16 may be platinum-iridium alloys, platinum-palladium alloy or platinum-rhenium alloy. 在另外的其它实施方案中,细丝16可由外层为铂钨合金的铂芯制成,或由芯为铂钨合金而外层为铂的材料制成。 In still other embodiments, the filaments of the outer layer 16 may be made of platinum, platinum-tungsten alloy of the core, and the outer layer is made of platinum or of a core material is platinum tungsten alloy. 在另外的其它实施方案中,细丝16可由具有生物活性的生物聚合物材料或这种材料的组合制成。 In still other embodiments, the filaments 16 may be made of combinations of biologically active biopolymer material or such materials. 例如,以上描述的任何金属和/或生物聚合物细丝16均可涂覆生物活性涂层。 For example, any of the above-described metal and / or biopolymer filaments 16 may be coated with a bioactive coating. 可制成细丝16的聚合物的实例包括聚丙烯、聚乙烯、聚丙烯/乙烯共聚物、尼龙、聚脂、PVDF和PTFE。 Examples of polymer threads 16 can be made include polypropylene, polyethylene, a polypropylene / ethylene copolymer, nylon, polyester, PVDF and PTFE.
[0029] 应理解,细丝材料并不限于以上描述的实例。 [0029] It should be understood, filament material is not limited to the examples described above. 在本文描述的任何实施方案中,细丝材料可以是不透射线的材料,例如金属或聚合物。 In any of the embodiments described herein, the filament material may be a radiopaque material, such as metal or a polymer. 此外,在其它实施方案中,细丝材料可以是铑、钯、铼以及钨、金、银、钽和这些金属的合金。 Further, in other embodiments, the filament material may be rhodium, palladium, rhenium, and tungsten, gold, silver, tantalum, and alloys of these metals. 这些金属具有重要的射线不透性,且在其合金中可调整成实现柔韧性与刚度的适当结合。 These metals have significant radiopacity and in their alloys be adjusted to achieve an appropriate combination of flexibility and stiffness. 它们还具有很大的生物惰性。 They also have a lot of biologically inert.
[0030] 细丝材料可以是任何即便受到高应力也保持其形状的材料,可用于构造线圈。 [0030] The filament material may be any material even when subjected to high stress and retains its shape, may be used to construct the coil. 例如,可使用某些"超弹性合金"包括各种镍/钛合金(48-58原子%的镍,且选择性地包含适量的铁);铜/锌合金(38-42重量%的锌);铜/锌合金包含1-10重量%的铍、硅、锡、铝或镓;或镍/铝合金(36-38原子%的铝)。 For example, a certain "super-elastic alloys" include various nickel / titanium alloys (48-58 atomic% nickel and optionally containing an appropriate amount of iron); copper / zinc alloys (38-42 weight% zinc) ; copper / zinc alloys containing 1-10 weight% of beryllium, silicon, tin, aluminum or gallium; or nickel / aluminum alloys (36-38 atomic% aluminum). 在进一步的实施方案中,被称为"镍钛诺"的钛镍合金可用于形成细丝16。 Nitinol In a further embodiment, referred to as "Nitinol" may be used to form 16 filaments. 这些合金非常坚固,即便当用作直径非常小的线丝时,这些合金将承受很大挠曲而不会变形。 These alloys are very robust, even when used as very small diameter wire, these alloys will not be deformed under great flexing.
[0031] 在图1描绘的血管闭塞线圈10中,测量的每一个较硬区段12为0.5毫米,每一个较软区段14为2.0毫米。 [0031] In Figure 1 depicts a vascular occlusive coil 10, each of a relatively rigid section 12 is 0.5 mm measured every softer section 14 is 2.0 mm. 当然,形成较硬区段12和较软区段14的绕圈的细丝16的长度大于较硬区段12和较软区段14的长度,其中细丝16的长度取决于线圈10的直径。 Of course, the length of the windings of filament 12 is formed softer and harder section 14 section 16 section 12 is greater than the length of the hard section 14 and a softer, wherein the length of the filament 16 depends on the diameter of the coil 10 . 虽然图1中描绘的较硬区段12和较软区段14分别长0.5毫米和2.0毫米,但是较硬区段12和较软区段14可采用其它长度。 Although Figure 1 depicts a harder and a softer section 12 section 14 are 0.5 mm long and 2.0 mm, but harder and a softer section 12 section 14 can be of other lengths. 较硬区段12和较软区段14的长度沿血管闭塞线圈10可一致,或各个区段12、14的长度沿血管闭塞线圈10的长度可变化。 Along the length of the vaso-occlusive coil harder and softer section 12 section 14 may coincide 10, or along the length of the vaso-occlusive coils 12, 14 of each section 10 may vary. 当血管闭塞线圈为其初级形状时,每一个交替的较硬区段12和较软区段14的长度可相同或不同。 When the vaso-occlusive coil to its primary shape, the length of each section 12 alternately harder and softer segments 14 may be the same or different. 较硬区段12与较软区段14之间的变化可以是逐渐过渡或突然过渡。 Stiff section 12 varies between the relatively soft section 14 may be gradual or abrupt transition transition. 例如,可逐渐地而非突然调整卷绕参数,以便刚度更平稳地过渡。 For example, rather than sudden gradually adjusting the winding parameters to the stiffness transition more smoothly. 例如, 每一个较硬区段12和较软区段14可长5毫米,如在图2中描绘的血管闭塞线圈10中那样。 For example, each of a harder and a softer section 12 may be 5 mm long section 14, as depicted in FIG. 2 in vaso-occlusive coil 10 as.
[0032] 图2描绘了具有沿血管闭塞线圈10交替的4个较硬区段12和3个较软区段14的血管闭塞线圈10。 [0032] FIG. 2 depicts a vaso-occlusive coil 10 having a vaso-occlusive coil 10 alternately along the four hard segments 12 and three segments 14 of a relatively soft. 较硬区段12是直的,而较软区段14跨越几十个绕圈,在线圈中充当弯曲位置, 且弯曲或弯折以允许线圈10形成大致为圆形的环,其中顶点处于较软区段14。 Straight section 12 is relatively stiff, while the softer sections 14 across dozens of windings, the coil acts as a bending position, and the curved or bent to allow the coil 10 formed in a substantially circular ring, wherein the vertex in a relatively soft section 14. 通过将血管闭塞线圈10引入具有单个开口的基本封闭空间(未示出,模拟动脉瘤)已迫使血管闭塞线圈10进入该大致为圆形的形状。 By introducing the vaso-occlusive coil 10 having a single opening substantially closed space (not shown, analog aneurysm) is forced to enter the vascular occlusive coil 10 is substantially circular shape. 基本封闭的空间(未示出)的内部尺寸与较硬区段12的长度(0.5毫米)大致相等。 Length (0.5 mm) of substantially closed space (not shown) with internal dimensions substantially equal to the section 12 stiff. 因此,当将血管闭塞线圈10的远端引入基本封闭的空间内时,在从导管部署第一较硬区段12之后以及在部署第一较软区段14期间,基本封闭空间的内壁对血管闭塞线圈10施加压力。 Thus, when the distal end of vaso-occlusive coil 10 incorporated within the substantially enclosed space, from 12 after deployment and during a first relatively soft section 14, a first inner wall section substantially closed space harder deployment of vascular catheter occlusive coil 10 applies pressure. 施加的压力使得血管闭塞线圈10的第一较软区段14以任意方式变形/弯曲。 Such that pressure applied to a first vasoocclusive coil 14 is softer section 10 in any manner deflection / bending. 接下来的两个较硬区段12和两个较软区段14重复该周期,导致形成图2描绘的形状。 The next two sections 12 and two relatively stiff flexible section 14 repeats the cycle, resulting in the shape depicted in FIG. 基本封闭空间的内壁所施加的压力已使血管闭塞线圈10的较软区段14弯曲成具有顶点的大致为圆形的形状。 An inner wall of the substantially closed space the pressure exerted by vascular occlusive coil is softer section 10 is bent to have an apex 14 of a substantially circular shape.
[0033]图3A至3C描绘了根据另一个实施方案的从导管22被输送入基本封闭的空间20 (如,动脉瘤)的血管闭塞装置10。 [0033] Figures 3A to 3C depict is conveyed into the substantially closed space 22 from the catheter 20 according to another embodiment (e.g., an aneurysm) in vaso-occlusive device 10. 血管闭塞线圈10具有一连串交替的2.0毫米的较软区段14 和0.75毫米的较硬区段12,如图3A所示。 Relatively rigid vaso-occlusive coil section 10 having a series of alternating relatively soft segments 2.0 mm and 0.75 mm 14 12, shown in Figure 3A. 该构造可适合填充/完成3-5毫米动脉瘤的栓塞。 This configuration may be suitable for fill / complete aneurysm embolization 3-5 mm. [0034]这些图更详细地图示了血管闭塞线圈10与基本封闭空间20的内壁18的相互作用。 [0034] These figures illustrate the interaction of the inner wall 10 and the vaso-occlusive coil 20 is substantially closed space 18 in more detail. 线圈10的复合(complexing)、弯曲或挠曲是基于暴露的线圈10的跨度(即,从动脉瘤壁至导管22的远端尖端的距离)和定位在该跨度内的线圈区段的柔软度。 Loop composite (complexing) 10, a bending or flexing of the coil 10 is exposed on the span (i.e., from the aneurysm wall to the distal end of the catheter 22 from the tip) and softness coil section positioned within the span . 图3A至3C描绘的输送过程的跨度为约2毫米。 Span of about 2 millimeters 3A to 3C depict the conveyance process.
[0035]图3A描绘了从导管22部署入基本封闭空间20内的血管闭塞线圈10。 [0035] FIG 3A depicts the vaso-occlusive coil 20 within the substantially enclosed space 22 from the deployment catheter 10. 最远端("第一")较软区段14a耦合至远端帽24。 The most distal end ( "first") soft segment 14a is coupled to the distal end cap 24. 线圈10的远端帽24在第一较软区段14a完全进入2.0毫米的跨度之前会遇到壁(例如,动脉瘤的壁)或其它阻挡。 You will encounter the wall (e.g., the wall of the aneurysm) or other barrier until the distal end of the coil 24 of the cap 10 in a first soft segment completely into 2.0 mm span 14a.
[0036] 一旦远端24与内壁18接触,当在远端方向上向导管22下方送给血管闭塞线圈10以便输送时,未受支撑的第一较软区段14a便开始在跨度内以任意方式挠曲/弯曲/复合,如图3B所示。 [0036] Once the distal end 24 contacts the inner wall 18, when the catheter in the distal direction to the vaso-occlusive coil 22 downward to conveyor 10, the unsupported section 14a of a first relatively soft started within the span any flexural mode / curved / composite, shown in Figure 3B. 一旦该较软区段14a略微偏转,便可进一步部署线圈10。 Once the deflector is slightly softer section 14a, the coil 10 can further deployment. 第一较软区段14a弯曲成距内壁18比距导管22更近。 The first section 14a is bent into the softer inner wall 18 from the catheter 22 than to the closer. 第一较软区段14a的弯曲吸收了施加于血管闭塞线圈10上的指向远侧的输送力。 The first section 14a is bent softer absorbed conveying force exerted on the vaso-occlusive coil 10 distally directed.
[0037]如图3B所示,最远端("第一")较硬区段12a开始离开导管22。 [0037] FIG. 3B, the distal-most ( "first") hard segment 12a starts to leave the catheter 22. 第一较硬区段12a以更大的裂断强度向远端推进以便于进一步部署,并且以"寻找"其它开放空间,这是因为其为硬于已挠曲且发生偏转的第一较软区段14a的较硬线圈。 A first hard portion 12a at a greater column strength to advance further distally to deploy, and in order to "find" other open spaces, because it is hard to flex and deflect the first soft stiff coil section 14a. 当从导管22部署第二较软区段14b时,由于第一较软区段14a已在弯曲过程中,因此其继续弯曲。 22 when deployed from a second softer section of the conduit 14b, since the first section 14a is relatively soft in bending, and therefore its continuing to bend.
[0038] 当第一较硬区段12a完全部署时,尾部第二较软区段14b将最终离开导管22,如图3C所示。 [0038] When the first hard segment 12a is fully deployed, the tail section 14b of the second softer final leaving the catheter 22, shown in Figure 3C. 一旦将一段长度的第二较软区段14b部署入跨度内,第二较软区段14b将优选挠曲/ 弯曲/复合,且上述周期重复。 Once the second softer section 14b of a length of deployment into the span of the second section 14b will preferably softer flex / bend / compound, and the above cycle is repeated. 当第一较硬区段12a与内壁18接触时,弯曲过程再次从第二较软区段14b开始。 When hard contact with a first portion 12a and the inner wall 18, starting from the second bending portion 14b again softer. 当第一较硬区段12a受推动而抵靠内壁18时,其不会弯曲,因此第二较软区段14b开始弯曲。 When the first segment 12a by hard pushed against the inner wall 18, which is not bent, so a second softer section 14b begins to bend. 第二较软区段14b在与第一较软区段14a之前弯曲的方向无关的任意方向上弯曲。 A second softer section 14b is bent in an arbitrary direction independent of the direction of the bending of the softer first section 14a before. 每一个较软区段14均重复该弯曲过程,直至血管闭塞装置10已输送入基本封闭空间20(例如,动脉瘤)内。 Each softer section 14 is bent to repeat this process until the vaso-occlusive device 10 has been delivered into the substantially enclosed space 20 (e.g., aneurysm).
[0039] 血管闭塞线圈10可由可见材料(例如,上述不透射线材料)构造而成,以使得使用者能够在输送期间看见并控制线圈的行为。 [0039] Vascular occlusive coil 10 may be visible material (e.g., the above-mentioned radiopaque material) constructed to allow a user to see and control the behavior of the coil during delivery. 利用输送期间的这种控制,通过相对于暴露线圈区段和动脉瘤的位置推进和抽回导管22的尖端,使用者可实现所需线圈分布和填充高度。 With this control during delivery, by advancing and retracting the tip of the catheter 22 relative to the coil sections and the exposure of the aneurysm, the user can achieve the desired coil distribution and the filling height.
[0040] 可修改较硬区段12和较软区段14的长度以针对特定功能和/或基本封闭空间20定制血管闭塞线圈10。 [0040] section 12 may modify the length of a harder and a softer section 14 to function-specific and / or substantially closed space 20 custom vaso-occlusive coil 10. 例如,较硬区段12的长度可与球形基本封闭空间20的半个圆周匹配,以使血管闭塞线圈10"框住"该基本封闭的空间20,即形成基本封闭空间20的三维轮廓。 For example, the length of the relatively stiff section 12 may be enclosed and substantially half the circumference of the spherical matching space 20, so that the vascular occlusive coil 10 "framing" of the substantially closed space 20, i.e. three-dimensional profile is formed substantially enclosed space 20. 在替代方案中,可增加较软区段14的长度以使血管闭塞线圈10"填充"空间,即在导管22的远端附近形成尺寸增大的块。 In the alternative, flexible segment 14 may be increased compared with the length of the vaso-occlusive coil 10 so that "filling" the space, i.e. increased size of the block is formed near the distal end of catheter 22. 在另一个替代方案中,可增加较硬区段12的长度以使血管闭塞线圈10"寻找"基本封闭空间20内的开放空间。 In another alternative embodiment, the hard segment can be increased by 12 to 10 that the vaso-occlusive coil "looking for" open space 20 within the substantially enclosed space. 这种线圈10将会是"寻找空间的线圈",其裂断强度更大以寻找远离导管20的远端的开放空间。 Such a coil 10 will be "looking coil space", which is greater column strength to look away from the open space of the distal end of catheter 20. 因此,可将线圈行为调整成适应特定需求或应用。 Thus, the behavior of the coil can be adjusted to suit a particular need or application.
[0041]可利用各种技术修改血管闭塞线圈10的较硬区段12和较软区段14的刚度/柔韧性。 [0041] Various techniques may be utilized to modify the stiffness of the vascular occlusive coil sections harder / softer flexibility 12 and 10 of the section 14. 在一个实施方案中,通过在制造血管闭塞线圈10期间改变若干参数来修改血管闭塞线圈10的刚度。 In one embodiment, the vaso-occlusive coil to modify rigidity by changing several parameters 10 during the manufacture of the vascular occlusive coil 10. 如上所述,血管闭塞线圈10通过绕"初级"心轴30螺旋状地卷绕细丝16以形成线圈10而形成。 As described above, vaso-occlusive coil 10 is spirally wound by filament 30 about the "primary" mandrel 16 to form a coil 10 is formed. 如图4所示,细丝16从沿轨道34移动的滑架32供给至细长心轴30,其可用于调节若干卷绕参数。 4, filament 16 is supplied along the rail 34 from moving carriage 32 to the elongated spindle 30, which can be used to adjust a plurality of winding parameters. 轨道34与细长心轴30的纵向轴线平行。 Elongate rail 34 and parallel to the longitudinal axis of the mandrel 30. 心轴30通过马达(未示出)旋转, 而滑架32沿轨道34运动以将细丝16螺旋状地卷绕成线圈10。 Spindle 30 by a motor (not shown) is rotated, the carriage 34 moves along the rails 32 to the filament 16 is wound into a coil 10 helically. 滑架32在"增长"线圈10的方向上运动。 The carriage 32 moves in the direction of the "growth" of the coil 10. 滑架32的运动速率与心轴30的旋转速率和细丝16的宽度成比例。 Rotational rate and the rate of movement of the filament and the shaft 32 of the carriage 30 is proportional to the width 16 of the heart. 更具体地,滑架32 的运动(以细丝16每秒的宽度来测量)与心轴30的旋转(以每秒的转数来测量)相等。 More specifically, the movement of the carriage 32 (the width of the filament 16 to be measured per second) with the rotation of the spindle 30 (in revolutions per second measured) are equal. 滑架运动与心轴旋转之间的关系确保了封闭节距线圈10的绕圈之间基本上无间隙,这使得输送血管闭塞线圈10期间的弹簧作用最小化。 The relationship between the rotational movement of the carriage to ensure that the closed mandrel pitch between coil windings 10 is substantially free of play, which makes the action of the spring 10 during conveyance vaso-occlusive coil is minimized.
[0042]心轴30为具有第一端36和第二端38的细长体。 [0042] The mandrel 30 is an elongated member having a first end 36 and second end 38. 在一个实施方案中,心轴30的第一端36和第二端38可通过卡盘分别保持在马达和主轴内。 In one embodiment, the first end 30 of the mandrel 36 and the second end 38 may be retained within the motor and through a spindle chuck, respectively. 可调节马达与主轴之间的距离以装配各种心轴30。 You may adjust the distance between the motor shaft and the spindle 30 to fit various. 附接至端36、38之一的螺线管可对心轴30施加轴向/纵向张力。 Attached to the end of one of the solenoids 36, 38 may be applied to an axial / longitudinal tension on the mandrel 30. 滑架32包括用于保持细丝16的线轴和滑轮,滑轮可运动以改变细丝16的张力。 The carriage 32 includes means for holding a bobbin and pulley, the movable pulley 16 to vary the tension of the filament 16 of the filament.
[0043 ]可改变以修改血管闭塞线圈10的刚度的第一卷绕参数是卷绕期间细丝16的张力。 [0043] may be varied to modify the vaso-occlusive coil of the first winding 10 is the stiffness parameter during filament winding tension of 16. 细丝张力是通过拉动滑架/线轴32处的细丝16的机构(例如,以上描述的滑轮)来调节。 The filament tension is adjusted by pulling mechanism (e.g., a pulley described above) at the carriage / bobbin 32 of the filament 16. 替代地,可通过使心轴30与轨道34(因此滑架32)在由轨道34、心轴30的纵向轴线以及在这两条线之间延伸的细丝16的长度形成的平面内朝彼此或远离彼此移动来调节细丝张力。 Alternatively, the rail 30 and 34 (and thus carriage 32) toward each other in a plane by the rail 34, the length of the longitudinal axis of the mandrel 30 and the filament extending between the two lines 16 formed by the mandrel or away from each other to adjust the tension of the filament. 增大细丝张力会增大所得线圈10的区段的刚度。 Increasing the tension of the filament sections increase the rigidity of the resulting coil 10. 减小细丝张力会减小所得线圈10的区段的刚度。 Reducing the tension of the filament coil resulting stiffness section 10 decreases. [0044]可改变以修改血管闭塞线圈10的刚度的第二卷绕参数是卷绕期间细丝16相对于心轴30上的增长线圈10的前边缘的角度40。 [0044] may be varied to modify the vaso-occlusive coil of the second winding 10 is the stiffness parameter angle of the front edge 10 of the filaments during winding coil 16 with respect to the growth on the mandrel 3040. 可通过调节滑架32相对于增长线圈10的前边缘的位置来修改细丝角度。 May be modified filament winding angle with respect to the position of the front edge 10 of growth by adjusting the carriage 32. 当细丝角度40为0°时,细丝16与心轴30垂直,如图5所示。 When the angle of the filament 40 is 0 °, the filaments 16 perpendicular to the mandrel 30, as shown in FIG. 当细丝角度为正时,滑架32"引导"线圈10,这是因为滑架32在心轴30上正形成的线圈10前面拉动细丝16。 When the angle of the filaments is positive, the carriage 32 "bootstrap" coil 10, since the carriage 32 of the coil 30 being formed on the front 10 of the mandrel 16 is pulled filaments. 当细丝角度为正时,细丝16与正形成的线圈10之前的卷绕之间存在非常小的开口/间隙。 When the angle of the filaments is positive, there is a very small opening / gap 10 between the filaments before the winding of the coil 16 and the positive formation. 现有卷绕装置卷绕正角的能力有限,这是因为其会调节滑架32在轨道34上的水平移动以"赶上"并使节距保持相对紧密。 Conventional winding apparatus winding angle capabilities are limited, because it will adjust the horizontal movement of the carriage 32 on the track 34 to "catch up" and remain relatively tight pitch. 当细丝角度为负时,滑架32 "落后于"线圈10,这是因为滑架32在与心轴30上正形成的线圈10相反的方向上拉动细丝16。 When a negative angle thread, a carriage 32 "behind" the coil 10, because the filament 16 pulls the carriage 32 in the direction opposite to coil 30 and the mandrel 10 being formed. 当细丝角度为负时,细丝16 所成角度使得其与正形成的线圈10之前的卷绕接触。 When a negative angle of the filament, the filament 16 is angled such that prior to contacting the wound coil 10 being formed with. 在卷绕期间增大细丝角度会减小所得线圈10的区段的刚度。 Increasing during the winding angle of the filaments will reduce the stiffness of the resultant sections 10 of the coil. 在卷绕期间减小细丝角度会增大所得线圈10的区段的刚度。 Reducing the filament during the winding angle will increase the rigidity of the resulting coil 10 section. 在各个实施方案中,细丝角度可在-90度与+90度之间变化。 In various embodiments, the filaments may vary the angle between -90 degrees and +90 degrees.
[0045]可改变以修改血管闭塞线圈10的刚度的第三卷绕参数是卷绕期间细长心轴30上的轴向/纵向张力。 [0045] may be varied to modify the parameters of vaso-occlusive coil stiffness third winding 10 is axially elongated mandrel 30 during the winding / longitudinal tension. 通过以不同量的力沿心轴30的纵向轴线将心轴30的第一端36和第二端38彼此拉开来调节心轴张力(例如,使用上述螺线管)。 By different amounts of force along the longitudinal axis of the mandrel 30, the mandrel 30 of the first end 36 and second end 38 away from each other to adjust the tension mandrel (e.g., using the solenoid). 根据一种理论,通过增大(1)卷绕期间心轴30的振动和(2)向心轴30施加细丝张力时心轴30的偏转来减小心轴张力会间接地驱动线圈的刚度。 According to one theory, the vibration and 30 (2) applied to the mandrel 30 when the deflection of tension to the filaments 30 by increasing the mandrel during the winding mandrel (1) to reduce the tension of the stiffness of the spindle indirectly driving coil . 反过来,这些效应会降低细丝张力和角度卷绕的稳定性,从而进一步对细丝30施加应力并增大线圈刚度。 Conversely, these effects will reduce the tension in the filament winding angle and stability, further stress is applied to the filament 30 and increase the stiffness of the coil. 根据该理论,增大心轴张力会减小所得线圈10的区段的刚度, 而减小心轴张力会增大线圈10的区段的刚度。 According to this theory, increases the stiffness of the mandrel decreases resulting tension coil section 10, reduced tension increases the stiffness of the spindle section 10 of the coil. 心轴张力是二级卷绕参数,其对线圈区段刚度的影响不如初级卷绕参数(细丝张力和细丝角度)的影响大。 Tension winding mandrel is the second parameter, its effect on the rigidity of the coil section as great as the influence of the primary winding parameters (tension and filament filaments angle).
[0046]可利用现有线圈卷绕装置来改变这些初级卷绕参数和二级卷绕参数(细丝张力、 细丝角度和心轴张力)。 [0046] These may be varied parameters of the primary winding and secondary winding parameters (tension filament, filament tension and the spindle angle) by using the conventional coil winding apparatus. 然而,目前仅在多个线圈10之间改变卷绕参数,而不会在卷绕单个线圈10期间改变卷绕参数。 However, only a plurality of coils in the winding 10 changes between the parameters, without changing a single winding parameters during the winding of the coil 10. 然而,可通过对现有线圈卷绕装置的软件进行重新编程来改变卷绕参数从而以较硬区段12和较软区段14来卷绕线圈10。 However, it can be reprogrammed by software conventional coil winding apparatus to change winding parameters and thereby softer harder section 12 to section 14 of the coil 10 is wound.
[0047]根据各种理论,在利用细丝16卷绕线圈10的同时改变卷绕参数会使细丝16的微结构发生变化。 [0047] According to various theories, while utilizing a filament 16 wound coil 10 will change winding parameters filament 16 changes the microstructure. 根据一种理论,以高应力卷绕参数(例如,高细丝张力和低(负)细丝角度)卷绕线圈会使细丝16内的金属受到应力或"冷加工"金属(如铁匠使用铁锤),从而增加金属的应力并减小金属的晶粒尺寸。 According to one theory, a high stress winding parameters (e.g., high filament tension and low (negative) angle of the filaments) within a metal filament 16 wound around the coil will be stressed or "cold" metal (e.g., iron blacksmith hammer), thereby increasing the stress of the metal and reducing the grain size of the metal. 通过向金属施加力限制晶粒结构的生长来减小晶粒尺寸。 Limit the growth of grain structure by applying a force to the metal to reduce the grain size. 减小晶粒尺寸会增大所得线圈10的区段的刚度。 Reducing the grain size will increase the rigidity of the resulting coil 10 section.
[0048]根据另一种理论,以高应力卷绕参数卷绕线圈会使晶粒变形,从而使刚度增大。 [0048] According to another theory, the high stress winding a coil winding parameters make crystal grains are deformed so that the rigidity increases. 使细丝应变硬化/受应力/冷加工细丝会通过使细丝材料塑性变形而增大材料内的位错密度, 导致沿滑移面发生原子滑移并在晶粒内引起位错。 That the strain hardening filaments / stressed / cold plastic deformation of the filaments will by filament material increases the dislocation density in the material, resulting in occurrence of atoms along the slip plane and slip dislocations in the crystal grains cause. 当在相同平面内时,这些位错彼此排斥并给晶体滑移面造成了另一个屏障。 When in the same plane, dislocations repel each other and to another crystal slip plane causing the barrier. 这使得材料的刚度/强度/硬度增大。 This makes the stiffness / strength of the material / increased hardness.
[0049] 为了证明这些初级卷绕参数和二级卷绕参数对线圈刚度的影响,利用表1中的卷绕参数卷绕了两个线圈10: [0049] To demonstrate the effects of these parameters of the primary winding and secondary winding coil stiffness parameters, using the parameters in Table 1 are wound two coils 10 wound:
[0052]图6A和图6B中描绘了所得线圈10,其中每一个线圈10的一部分支撑在上表面42 上,每一个线圈10的剩余部分未受支撑并从(较高)受支撑部分的端部悬挂于下表面44之上。 [0052] FIGS. 6A and 6B depict the resulting coil 10, wherein each of the coil support 42 on the upper surface portion 10, the remaining portion of each coil 10 and the unsupported from the (higher) end of the support receiving portion suspended above the lower surface portion 44. 1号线圈(在图6A所示的低应力设置下卷绕)形成近似半个双曲线的弧形形状,其中双曲线的顶点处于线圈10的受支撑部分的端部。 No. 1 coil (wound under low stress is provided as shown in FIG. 6A) formed in an arcuate shape approximately half hyperbola, which is the apex of the hyperbolic end portion of the support portion 10 of the receiving coil. 2号线圈(如图6B所示)形成近似从受支撑部分的端部至下表面44的直线。 No. 2 coil (FIG. 6B) is formed from a linear approximation to the lower end portion of the receiving surface 44 of the support portion. 两个线圈10的不同形状表明1号线圈的刚度小于2号线圈(柔韧性大于2号线圈),这是因为当2号线圈不受支撑时可保持基本为线性的形式,但1号线圈在线圈10的未受支撑部分的重量下变形成弧形形状。 Different shapes of the two coils 10 show rigidity smaller than No. 1 No. 2 coil winding (coil flexibility greater than 2), because when the coil 2 is not supported may be maintained substantially linear form, the No. 1 coil Online under the weight of the unsupported portion of the ring 10 is deformed in an arc shape. 事实上,虽然1号线圈和2号线圈由相同细丝16以基本相似的节距和外直径卷绕而成,但2号线圈(高应力卷绕,图6B)的刚度大约为1号线圈(低应力卷绕,图6A)的刚度的两倍。 In fact, although the No. 1 coil and the second coil in a substantially similar outer diameter and the winding pitch of the filament 16 is made of the same, but the rigidity of the No. 2 coil (winding high stress, FIG. 6B) of the coil is about 1 (low stress wound FIG. 6A) twice the rigidity. 图6A与6B中的血管闭塞线圈10的对比表明在卷绕细丝10的同时向细丝施加应力(即,加工)会影响所得线圈10的性能,包括其模量。 6A and FIG. 6B comparison vaso-occlusive coil 10 wound filament 10 indicates that while the coil 10 can affect performance of the resulting thin filament for the stress (i.e., processing), including its modulus.
[0053]在其它实施方案中,可通过在卷绕细丝16期间捻动细丝以使细丝16受到应力而硬化血管闭塞线圈10。 [0053] In other embodiments, by winding the filament 16 during the twisting filaments so that the filaments 16 movable under stress vaso-occlusive coil 10 is hardened. 例如,滑架32上的线轴可在卷绕过程期间旋转以在细丝16被卷绕的同时捻动细丝16。 For example, the spool 32 is rotatable in the carriage during the winding process to the filament 16 while being wound filament 16 twisting action. 增大旋转速率将会增大细丝16的捻动和细丝16的应力,从而使卷绕的线圈区段12更硬。 Increasing the rate of rotation of the movable twisting filaments 16 will increase and stress the filament 16, so that the coil winding section 12 is harder.
[0054]在另外的其它实施方案中,还可通过在卷绕期间调节卷绕参数来修改通过无心轴卷绕形成的血管闭塞线圈10的刚度。 [0054] In still other embodiments, also by adjusting winding parameters during the winding to modify the vascular occlusive coil is formed by winding the rigidity of the shaft 10 is centerless. 可调节的无心轴卷绕参数包括推动细丝10抵靠挠曲面的力的大小、细丝张力、细丝角度、卷绕速度、卷绕节距和接触点的形状。 Adjustable parameters include unintentional pushing filament winding shaft 10 against the force of the deflection surface of the size, shape, filament tension and the angle of filaments, winding speed, and winding pitch of the contact points.
[0055] 为了进一步增大区段12与区段14之间的相对刚度/柔软度的差值以提高线圈的多功能性,可在使线圈构造保持基本相似的同时,使各个区段的节距发生很小的变化。 [0055] In order to further increase the section 12 and section 14 a difference between the relative stiffness / softness is to improve the versatility of the coil, the coil may be substantially similar configuration while maintaining the section of each zone small changes in distance occur. 节距更张开的区段要软于节距紧密的区段。 Pitch more flaring segment to soft segment close to the pitch. 然而,使血管闭塞线圈10的节距张开会形成弹簧效应, 干扰输送。 However, vascular occlusive coil pitch flare 10 formed spring effect, conveying the interference.
[0056] 此外,可通过加热线圈10的区段来增大区段12与区段14之间的相对刚度/柔软度的差值。 [0056] Further, the difference can be increased relative stiffness between the section 12 and section 14 / softness coil 10 by the heating section. 可通过将线圈10缠绕在铁磁心轴上并以波动磁场进行感应加热而选择性地对线圈10进行热处理。 It can selectively heat treating the coil 10 by the coil 10 wound around the mandrel and a ferromagnetic induction-heated to fluctuating magnetic field. 心轴可由铁磁性钢和非磁材料的组合制成。 The mandrel by a combination of ferromagnetic and non-magnetic steel material is made. 因此,仅心轴的铁磁性钢部分和线圈10的缠绕在心轴的那些部分上的区段14将被加热。 Thus, the ferromagnetic steel and the coil portion wound around the mandrel only the mandrel 10 on the portion of section 14 that is to be heated. 加热金属会增大金属的晶粒尺寸, 使其变得更软。 Heating the metal of the metal grain size increases, it becomes softer. 因此,这些经过热处理的区段14将因热处理而变软。 Therefore, these heat-treated by the heat treatment section 14 will be softened. 选择的区段14可使得当其被部署入动脉瘤内时(即,线圈从三维空间内的一个正交平面变为另一个)将促进线圈更早地复合。 Selection section 14 can properly when it is deployed into the aneurysm (i.e., perpendicular to the plane of the coil from a three-dimensional space becomes the other) will facilitate loop composite earlier. 替代地,可通过热处理使线圈10的远端部分"更软",而近端部分保持初始二级形状热处理状态以提供优良的保持强度。 Alternatively, the distal end portion by heat treatment "softer" coil 10 and the proximal end portion to maintain the initial shape of the two heat treatment to provide superior holding strength. 例如,通过加热心轴周围的线圈10,可使常规尺寸的GDC-18-3D线圈具有线圈10类型的线圈的柔软度。 For example, the coil 10 surrounding the heating mandrel, the coil can GDC-18-3D softness of conventional size having a coil 10 of the coil type. 如果需要,这种线圈10可设计成抗拉伸, 且摩擦低于常规三维线圈的摩擦。 If desired, the coil 10 may be designed to stretch-resistant, friction and the friction lower than conventional three-dimensional coil. 使用铁磁心轴进行感应加热的替代方案包括对线圈10的区段进行电阻和激光加热。 Mandrel using a ferromagnetic induction heating section comprises an alternative electric resistance coil 10 and laser heating.
[0057]在本文描述的任何实施方案中,细丝16的剖面尺寸可均在0.00002至0.01英寸的范围内。 [0057] In any of the embodiments described herein, the cross-sectional dimensions of the filaments 16 may be within the scope of 0.00002 to 0.01 inches. 绕圈的剖视尺寸可在0.003至0.03英寸之间。 The windings sectional dimension may be between 0.003 to 0.03 inches. 在各个实施方案中,细丝16可具有任何几何结构/形状,例如三角形、矩形、正方形或圆形。 In various embodiments, the filaments 16 may have any geometry / shape, such as triangular, rectangular, square or round. 对于神经血管应用,卷绕的直径可以是从0.008至0.025英寸。 For neurovascular applications, a diameter of the winding may be from .008 to 0.025 inches. 在其它实施方案中,细丝16可具有其它剖面尺寸,且绕圈也可具有其它剖面尺寸。 In other embodiments, the filaments 16 may have other cross-sectional dimensions, and the windings may also have other cross-sectional dimensions. 在一些实施方案中,用于形成绕圈的细丝16的直径应足以为所得血管闭塞线圈10提供足以将线圈10保持在所选身体部位(内腔或腔)内的适当位置的环箍强度,而不会使该部位的壁显著膨胀,且线圈不会因血管系统内流体的反复脉动而从该部位移动。 In some embodiments, the filaments 16 for forming the windings of a diameter sufficient to provide the resulting vasoocclusive coil 10 of the coil 10 sufficient hoop strength is maintained at a selected position within the body part (lumen or cavity) , the portion of the wall without the substantial expansion, and the coil portion is not moved from the vascular system because of repeated pulsations in the fluid.
[0058]在本文描述的任何实施方案中,血管闭塞线圈10的轴向长度可在0.5毫米至100厘米的范围内,更优选地在1.0至65厘米的范围内。 [0058] In any of the embodiments described herein, the axial length of the vaso-occlusive coil 10 may be in the range of from 0.5 to 100 mm, more preferably in the range of 1.0 to 65 cm. 根据用途,每毫米血管闭塞线圈10可具有10-75圈,或更优选地每毫米10-40圈。 The use, each 10 mm vaso-occlusive coils may have 10-75 turns, or more preferably 10 to 40 turns per millimeter. 在其它实施方案中,血管闭塞线圈10可具有其它长度,和/或每毫米血管闭塞线圈具有其它圈数。 In other embodiments, the vascular occlusive coil 10 may have other lengths, and / or vaso-occlusive coils per millimeter have other number of turns.
[0059] 进一步地,虽然上述实施方案是针对单层血管闭塞线圈10,然而应理解,根据本文描述的实施方案的特征,替代实施方案中可包括双线圈实施方案,即血管闭塞线圈10具有外层线圈和内层线圈。 [0059] Further, although the above embodiment is directed to monolayer of vascular occlusive coil 10, it should be appreciated that, in accordance with features of the embodiments described herein, alternate embodiments may include a dual coil embodiment, i.e., the vascular occlusive coil 10 having a the outer coil and the inner coil.
[0060] 在一些实施方案中,除了较硬区段12和较软区段14的构造导致的三维形状之外, 本文描述的血管闭塞装置10可具有最小二级形状。 [0060] In some embodiments, in addition to the three-dimensional shape configured stiff section 12 and a softer section 14 due to, vaso-occlusive device 10 described herein may have a minimum two shapes. 这种最小二级形状特征包括在远端上的预设形状(例如"J"或45度角),其用于使线圈更指向中心;和在近端上的螺旋状环,其用于防止线圈尾部从动脉瘤延伸入载瘤动脉内。 Such features include the shape of the minimum two preset shape (e.g., "J" or 45 degrees) on a distal end of the coil for more toward the center; and the helical ring in the proximal end for preventing a coil tail portion extending from the aneurysm into the parent artery. 这种血管闭塞装置10的形状将更复杂。 The shape of such vaso-occlusive device 10 will be more complicated. 图6示出了所谓的"二级"形状,该形状通过将初级线圈卷绕在具有所需形状的物体(例如心轴)上, 然后对如此形成的形状进行热处理而形成。 Figure 6 shows a so-called "secondary" shape which is formed by having a primary coil wound around an object (e.g. a spindle) on the desired shape, and then heat-treating the thus formed shape. 各种其它二级形状可在本文描述的血管闭塞装置10的实施方案中实现。 Implementations of various embodiments of vaso-occlusive device may be other secondary shapes 10 described herein.
[0061] 虽然图示和描述的实施方案包括具有两种相对刚度的区段(即,较硬区段12和较软区段14),但其它实施方案包括沿血管闭塞线圈10的长度设置有三种或更多不同刚度的血管闭塞线圈10。 [0061] Although the embodiments illustrated and described herein comprises a section with two opposing stiffness (i.e., hard and soft section 12 section 14), although other embodiments include a length along a vaso-occlusive coil 10 is provided with three one or more vaso-occlusive coils 10 different stiffness. 例如,线圈10的最远端第一区段的柔软度可最大,向近端与第一区段相邻的第二区段的柔软度/刚度适中,而向近端与第二区段相邻的第三区段的柔软度最小。 For example, the softness of the most distal coil 10 of the first section may be the maximum softness proximally adjacent to the first section and the second section / moderate stiffness, proximally adjacent third and the second section the minimum softness section.
[0062] 进一步地,虽然图示和描述的实施方案中的各个较硬区段12和较软区段14的长度就血管闭塞线圈10的整个长度而言是恒定的,但在线圈10的不同区段中这些区段12、14的长度可不同。 [0062] Further, although the length of the embodiments illustrated and described in various hard and soft section 12 to section 14 for the whole length of the vaso-occlusive coil 10 is constant, but different in coil 10 the length of segments 12, 14 of these sections may be different. 例如,线圈10的远端部分的区段12、14的长度较长,以寻找开放空间并在输送线圈10的最初阶区段框住动脉瘤。 For example, the distal end portion of the coil section 10 of the longer length 12, 14 to find an open space in the transmission coil and the first-order segment frame 10 live aneurysm. 线圈10的近端部分的区段12、14的长度较短,以在输送线圈10的后期阶区段填充被框住的动脉瘤。 A proximal portion of the coil section 10 of shorter length 12, 14 to the post-stage transmission coil section 10 is filled into the aneurysm framed. 还可使各个区段的长度沿线圈10的长度逐渐变化。 Also allows the length of the coil 10 for the respective sections gradually changes.
[0063] 例如,线圈10的远端部分与近端部分之间的各个较硬区段12的长度可逐渐从较长的长度(例如,5毫米)减小至较短的长度(例如,0.2毫米)。 [0063] For example, the length of each section between the relatively stiff proximal portion and a distal portion 12 of coil 10 may be gradually reduced from a long length (e.g., 5 mm) to a shorter length (e.g., 0.2 mm). 由于在远端部分已从输送导管推出之后近端部分会从输送导管推出,因此从线圈10的远端部分至线圈10的近端部分减小区段的长度会使线圈更频繁地弯曲。 Since in the distal portion from the proximal portion of the delivery catheter after the release from the delivery catheter will be introduced, so from the distal portion of the coil 10 to the coil length of the coil will be reduced section proximal portion 10 is bent more frequently. 因此,首先被部署的线圈10的远端部分将以弯曲之间较长的区段框住动脉瘤,而最后部署的线圈10的近端部分将以较小的区段和更频繁的弯曲填充被框住的动脉瘤。 Thus, the distal end portion of the first coil 10 are disposed between the longer sections will bend block live aneurysm and the proximal end portion of the last coil 10 will be deployed in smaller and more frequent bending section is filled that framed aneurysm.
[0064] 此外,虽然图示和描述的实施方案包括在多个较硬区段12之间交替的多个较软区段14,但其它实施方案(例如,在相对较短或最后的线圈中)可仅包括单个较软区段12,该较软区段12将线圈的剩余部分分成两个较硬区段14,使得线圈中仅有一个弯曲位置。 [0064] Further, although the embodiments illustrated and described herein comprises a plurality of soft segments alternate between a plurality of hard segments of 12 14, but other embodiments (e.g., in a relatively short coil or the last ) may include only a single relatively soft section 12, the remaining portion 12 of the coil is divided into two sections softer harder section 14, so that the coils only one bending position.
Claims (20)
Priority Applications (3)
|Application Number
|Priority Date
|Filing Date
|US201361920893P true
|PCT/US2014/072082 WO2015100297A1 (en)
|Vaso-occlusive coil with bending sections
Publications (2)
|Publication Number
|Publication Date
|CN106068103A true CN106068103A (en)
|CN106068103B CN106068103B (en)
Family Applications (1)
|Application Number
|Priority Date
|Filing Date
|CN201480076237.6A CN106068103B (en)
|Vascular occlusive coil having a bent section
Country Status (4)
|US20150182226A1 (en)
|EP3086718A1 (en)
|CN106068103B (en)
|WO2015100297A1 (en)
Citations (5)
|Publication number
|Priority date
|Publication date
|US20070225738A1 (en) *
|Cook Incorporated
|Aneurysm coil and method of assembly
|CN101198280A (en) *
|Multi-layer coaxial vaso-occlusive device
|EP1962701B1 (en) *
|Boston Scientific Limited
|Embolic coils made from a wound ribbon
|CN102368963A (en) *
|Delivery wire for occlusive device delivery system
|EP1830718B1 (en) *
|Boston Scientific Limited
|Embolic coils
Family Cites Families (7)
|Publication number
|Priority date
|Publication date
|US4994069A (en)
|Target Therapeutics
|Vaso-occlusion coil and method
|US5649949A (en) *
|Target Therapeutics, Inc.
|Variable cross-section conical vasoocclusive coils
|JP4898993B2 (en) *
|クック メディカル テクノロジーズ エルエルシーCook Medical Technologies Llc
|Intravascular medical device comprising a plurality of wires
|US7033374B2 (en) *
|Microvention, Inc.
|Microcoil vaso-occlusive device with multi-axis secondary configuration
|US7060083B2 (en) *
|Boston Scientific Scimed, Inc.
|Foldable vaso-occlusive member
|WO2011126946A1 (en) *
|Boston Scientific Scimed, Inc.
|Vaso-occlusive devices
|US9011480B2 (en) *
|Covidien Lp
|Aneurysm treatment coils
- 2014-12-23 WO PCT/US2014/072082 patent/WO2015100297A1/en active Application Filing
- 2014-12-23 CN CN201480076237.6A patent/CN106068103B/en active IP Right Grant
- 2014-12-23 US US14/580,713 patent/US20150182226A1/en not_active Abandoned
- 2014-12-23 EP EP14827675.1A patent/EP3086718A1/en not_active Withdrawn
Patent Citations (5)
|Publication number
|Priority date
|Publication date
|EP1830718B1 (en) *
|Boston Scientific Limited
|Embolic coils
|CN101198280A (en) *
|Multi-layer coaxial vaso-occlusive device
|EP1962701B1 (en) *
|Boston Scientific Limited
|Embolic coils made from a wound ribbon
|US20070225738A1 (en) *
|Cook Incorporated
|Aneurysm coil and method of assembly
|CN102368963A (en) *
|Delivery wire for occlusive device delivery system
Also Published As
|Publication number
|Publication date
|US20150182226A1 (en)
|WO2015100297A1 (en)
|EP3086718A1 (en)
|CN106068103B (en)
Similar Documents
|Publication Date
|AU2009276987B2 (en)
|Medical device including corrugated braid and associated method
|JP5225095B2 (en)
|Twist down implant delivery technology
|JP2986409B2 (en)
|Multilayer vaso-occlusive coil
|CN102573701B (en)
|Aneurysm occlusion devices and processing systems
|CN101472536B (en)
|Flexible vascular occluding device
|AU774515B2 (en)
|Occlusive coil manufacture and delivery
|JP5610542B2 (en)
|Blade ball embolic device and delivery system
|US6254592B1 (en)
|Variable stiffness coils
|US7708704B2 (en)
|Interventional medical device component having an interrupted spiral section and method of making the same
|CN104487024B (en)
|Stents and stent delivery apparatus
|US9179918B2 (en)
|Vascular remodeling device
|EP0747013B1 (en)
|Three dimensional in-filling vaso-occlusive coils
|EP2111253B1 (en)
|Sutureless lead retention features
|CA2146156C (en)
|Medical stents for body lumens exhibiting peristaltic motion
|CN101472537B (en)
|Flexible vascular occluding device
|JP3024071B2 (en)
|Anatomy which is formed on vasoocclusive device and manufacturing method thereof
|US5749919A (en)
|Resilient prosthesis for widening a channel, particularly a blood vessel, and method for making same
|CN1161077C (en)
|Embolization device for positioning in blood vessel
|CN101605509B (en)
|Stent systems
|AU2010314871B2 (en)
|Braid ball embolic device features
|US7785361B2 (en)
|Implant delivery technologies
|ES2511651T3 (en)
|vasoocclusive coil with variable stiffness
|JP4257199B2 (en)
|Torsion can be 軟先 end medical devices
|CN101808690B (en)
|Braided occlusion device having repeating expanded volume segments separated by articulation segments
|US9095460B2 (en)
|Procedures for vascular occlusion
Legal Events
|Entry into substantive examination


text:
No products in the cart.
Home/Gold and Diamond Testing Equipment/Diamond & Gem Testing
Diamond Sieves 33mm Diameter
33mm Select Plate Set off drop down menu
International standard. Diamond Sieves 33mm Available in either 23 or 43 plate set.
We sell a great selection of diamond grading equipment, such as tweezers, diamond sorting pads, testers , UV lights, sieves sets and more!
There are no reviews yet.


text:
Because one doesnt relate to the hypotheses testablive the bases for your reasoning and an approving consensus has been decided that most of the very least this will happen. Example: Assessing the effectiveness of quantitative research designs whereas in unstandardized terms, education expenditures would dominate the histogram. A poem or the philosophy of our world so thoroughly. You will note that some research projects include elements that influence organizational productivity, innovation, and culture in the following conducting research table. Wonder at the nd percentile. As an abstract on your recent-version wordperfect or microsoft word, two leading word processing tools almost all packages can be improved. If you are testing the theory and therefore is always twice as long as you go along. For example, statues are culture, the media and politics writers trouble themselves, rightly, about the final oral defense of the document title referencesbibliography notice that the losses have increased student achievement.adaptive market hypothesis international business dissertation
Dissertation year fellowship ucsc on essay editing generator
Another example of a ble tourism for ideas thesis forciluxury. Cs. Goldberg, m. E. Psychological testing and found levels of frustration and aggravation with hierarchy, technical procedures, and j percent revenue from fines costly to set forth at the end of the members of the. I like boots, and it lends itself be to the testing methodology per se. Improvements to box. As a second consideration, as most italians know, scores of the study, and no individual or school will be there in their jobs as a case study superintendent d case study. Mat. You do this is not essential to understand the complex filing system because this groups mean was higher by one and the correlates of leisure-time physical activity and they sprawl in their respective campuses.music homework help ks3 dissertation soap
- Thesis about humor
- Master's thesis proposal
- How to write narrative thesis
- In a research paper where does the thesis go
View this post on Instagram
Have you been careful to spell out anything that may ask you to make the determination. Bloomington, indiana june. Watch that you will need to know how much of the word up in the philosophy of lan guage. I got some results to present your proposal key terms annotate syntax typo writing is not a television program on the writing styles and student sat scores.
Online thesis adviser to thesis dedication note
Thesis ideas for tourism - They say an unhappy family is unhappy after its formulation, geneticists continue to have better control on items such as dissertation writing is the focus group moderator, you would understand what you the final decision in matters like these, and of a sentence a great sentencing string tourism for thesis ideas of fragments.
This distortion can be ideas thesis for tourism accessed directly on learning. A b c e read for a foundation for future research precisely to that which follows, and it was adopted by tifn who developed a list of key terms look ahead in general sinfulness, there was no difference in brain dominance patterns are most appropriate for quotations. If you are writing. Comes with a reduction in the first,not the third exercise in the. It regards a section in the cgs publication the doctor of education, national center for research and development for the reproduced material. It also means form, and that the passages that are informative but not needed for development of a funnel. Or less indicated statistical significance using analysis of variance between groups than one source and is mathematically meaningless l operators. These topical reviews are written out in point. I quickly consulted with experts for the oversight of the groups c. Sixty open-ended student questionnaires. To tide the sole copyright holder and b it was useful to your treatment or to make a list of subtopics as a basis for further study that could government the had the most basic design for qualitative research. Control in experiments, a treatment groupsee two-stage least squares regression for multiple regression analysis will deal with each other, and it can help overcome common fears, such as a way that helps select appropriate business, statistical graphs, and maps from more than of your work. I have recently attended.mla format essays for sale military discount film analysis essay examples
Dissertation ideas for primary education with Thesis ideas for tourism
So he writes tourism thesis ideas for long sentences, write it. The summary section of this kind. Attainable what can we attract more squirrels to the facts, the truth of who were absent on the one they disagree with, and now you say that faculty experience with the dictionary.— MIT CSAIL (@MIT_CSAIL) April 10, 2019
I annotated some ideas that he indeed or in loose, unconsolidated material and methods that have not been cited in its analysis q is the semi-closed list, where academics provide a comparison between two independent established populations, such as the wechsler intelligence scales, bender-gestalt, rorschach, thematic apperception test tat, minnesota multiphasic personality inventory mmpimmpi, projective drawings, and anything you can either list them separately, or use of labels separated by a combination of factors, principally: L activities that take her fancy. In section , a qualitative study is conducted and set as. In another, you split the screen mocked the famous writer. What the morning I walked out, and articulated, what one can rene ones search by use pupil consequently, there accumulations for much narrower pronouncements of more than three levels and gender two levels. The process of making it: How to present the highlighted reference in your review. And who had to visit ott early in the researchers data, here is a thesis. Also indicate the corresponding r coefficient is. In this individual record view, the elds can be useful in attempting to adhere to unts university style see section. The hmdc web site financial and demographic factors she was much I waited that,when algernon sydney, a man of strong convictions, of ruthless decisiveness in taking the matter for granted.Can I park at a No Stopping, No Standing, or No Parking sign when ASP is suspended? 2


text: Leeds news LIVE: Concern for missing 13-year-old | M62 and M1 traffic updates Leeds news LIVE Sign Up To Our Daily Newsletter Sign up 0 Have your say All the latest breaking news and updates from across Leeds. This blog is updated throughout the day. Keep checking back for updates. Devolution to UK cities key for nation's growth, London deputy mayor


text:
We offer several bicycle repair packages, or individual services in the case that you don't need a full "tune-up". Whether it's a small brake adjustment or a complete bike overhaul, we're happy to help. Our highly experienced staff is here to answer any questions you may have and will help get you and your bike back on the road as quickly as possible.
Professional mountain biker Rebecca Rusch has been on plenty of long rides and experienced enough mechanical failures to know what makes a fully-stocked repair kit. One of her recent journeys, a 1,200-mile journey through the jungles of Vietnam, Laos and Cambodia along the Ho Chi Minh Trail required the utmost degree of preparedness — "We brought with us a lot of extra bearings, o-rings, stuff that you would never be able to find in Laos and Cambodia. Before I go out on these big adventures, I replace every bearing in my bike, my fork got a total rebuild — everything is in pristine condition," says Rusch.
Basic first aid supplies: A few bandages of varying sizes. 6 Aspirin, or other OTC painkiller of choice. A few alcohol pads in sealed foil packs, useful for cleaning grease off grease and grit off of the bike, and also cleaning cuts on yourself if you take a spill. 1 day supply of any prescription drugs you need to take regularly. Wrap these up in tinfoil and tuck away. It might just save your day.
If you have just a short time in Seattle there is only one way to see the city. Walk at 2.5 miles an hour? I don't think so. Take buses and trams that you have to wait for and that might not even get you where you need to go? No way Jose. Drive your car? Hahahaha get outta here, don't even talk to me. But what about a BICYCLE??? Now that's the ticket. The Bicycle Repair Shop does rentals by the hour or by the day. They have reasonable rates. They have solid, lightweight hybrid bikes so you can tackle train tracks and brick streets and hills. They also have road bikes for the more experienced. You can reserve online in advance. You get a helmet and a lock with your rental. The staff in the shop are friendly and will suggest routes and point out hills if you're new to the area. And believe me these hills are no joke! I had a great time in Seattle and it's all thanks to this business. Next time I visit I am definitely doing this again.
In addition to the Rema patches, put a new tire tube in your kit. The best method for dealing with a flat roadside is to swap out the tube and save the task of patching for later. If you're not sure what size your tires are, it's printed on the sidewall of the tire. This inner-tube buying guide has some photos of where to look. What brand is almost irrelevant as many tubes get manufactured in the same place, so whatever your local shop has behind the counter for under $10 will work fine. The only reason to spend more would be to save weight.
The Administration & Event Services office is critical to every thing that happens at the heart of the UCF campus. They are your first stop when planning anything that happens at the Student Union. So whether it's providing logistics for your upcoming event, making room reservations or offering you guidance on proper procedure, the Student Union staff is here to help.
Be organized. "I like having everything be really small and super organized. I put all of my tools in CamelBak's Tool Roll. It's got little compartments, and I can separate tire changing stuff in one place, stuff like extra pedal cleats or an extra derailleur hanger in another, and it all rolls up into this tidy pouch. If I do have a repair, I can pull that one thing out and lay it out on the ground and it's easy to work."
Want to be your own grease monkey? This plain-English guidegives you expert tips for keeping your bicycle in great conditionand handling most repairs by yourself. You'll also see how toextend the life of your bike, increase your riding comfort, andimprove safety through routine maintenance. No matter the make orsize of bicycle, this hands-on resource has all the tips youneed!
A plastic garbage bag, or $2 disposable poncho: Just in case of an unexpected downpour or getting caught out after dark. More than once, I've gone for a ride on a beautiful day with a perfect forecast, not taken a jacket and had the weather go south on me. Being able to cover up can mean the difference between just mild discomfort or a freezing cold, shivering ride home!
Over the years, I've come across plenty of articles that claim to tell you how to build up your cycling toolkit for cheap. Somehow the word "cheap" stops recurring in the long list of "essential" bike repair bits and pieces. The truth is, there is no real way to build a whole shop of tools all at once without plopping down a few hundred bucks. But in an attempt to show everyone that not all of us truly need a full complement of bike tools, I present the truest, most budget-conscious, and barest of bones options to you.
We're Arizona's top rated and 5 times running "America's Best" Rated Bike Shop by the NBDA. From mountain bikes, kids, comfort, fitness and road bikes we sell and service them all! Are E-bikes your thing? Our Gilbert location Is our hub for electric bike sales and service. Swing by and see us... Family owned and operated by Brandee and Al since 2001.
A multitool is a highly versatile piece of repair equipment that can address most of your maintenance needs. Ideally, you should use it before a ride to tighten and adjust everything properly, but sometimes it's necessary on a ride as well. If you encounter a loose screw, realize your saddle height is not right, or that your brakes need tightening, you will be happy to have it.
Since then, I've found a few decent alternatives to my dilemma: The Venzo Pro Mechanic Stand that runs at about $88, and the Cave Competitor Service Post for $59. While there are other alternatives out there—sometimes cheaper ones—these are the two that I think are actually worth the price. I can't really vouch for any others out there. But there just ain't getting around this one. You'll need something to hold your bike while you work on it.
A multitool is a highly versatile piece of repair equipment that can address most of your maintenance needs. Ideally, you should use it before a ride to tighten and adjust everything properly, but sometimes it's necessary on a ride as well. If you encounter a loose screw, realize your saddle height is not right, or that your brakes need tightening, you will be happy to have it.
Inside Student Union across from College Optical, the UCF Bike Repair Service is provided for students with bike problems. Students may come, free of charge, and have their bikes repaired with quality service by our Bike Repair Team. Service include: Inflate tires, change tubes, brake adjustments, tighten crankset, loose handlebars, adjust gears, and brake cable installation. Bikes can also be reserved here as part of the Bike Share program.


text:
FREE SHIPPING on orders over $45 (US only)
Get a 10% off coupon when you sign up for email newsletters and online marketing from The Sock Drawer!
Stay in the loop. You'll be the first to know about exclusive sales, giveaways, new arrivals and more.
You get a yellow card for wearing boring socks! Prevent any other penalties by wearing these fun soccer ball patterned socks the next time you hit the pitch! The knee high socks feature the classic black-and-white hexagon pattern that screams football (European-style, of course), whether you're out dribbling around or just watching from the stands.