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Artisanal small-scale gold miners have high levels of mercury in human specimens often above recommended threshold values. There are differences reported in the manifestation of neurological symptoms of individuals with a comparable level of exposure to mercury, suggesting a genetic component influencing the susceptibility to mercury neurotoxicity.
This article was published in the following journal.
Name: Environmental research
Pages: 108512
Role of ERK1/2 in TNFα-induced internalization of Abcc2 in rat hepatocyte couplets.
TNFα is a cytokine whose levels are increased in inflammatory pathologies that are associated with cholestasis. Endocytic internalization of Abcc2 (multidrug resistance-associated protein 2), a canal...
Association between STAT4 polymorphisms and the risk of juvenile idiopathic arthritis in Han Chinese populations.
Previous studies have demonstrated a potential role of STAT4 polymorphisms in increased juvenile idiopathic arthritis (JIA) risk in Caucasian populations; however, their role remains unclear in Han Ch...
Potential of Organic Mercury-resistant Bacteria Isolated from Mercury Contaminated Sites for Organic Mercury Remediation.
Efforts at organic mercury detoxification can be carried out using resistant bacteria that can live in an environment contaminated with the compound. This study aimed at isolating and identifying resi...
Prenatal exposure to mercury in relation to infant infections and respiratory symptoms in the New Hampshire Birth Cohort Study.
Mechanistic studies support the potential for mercury (Hg) to alter immunity, including via in utero exposure. As yet, there are few prospective studies of in utero Hg exposure and subsequent immune-r...
Potential of mercury-tolerant bacteria for bio-uptake of mercury leached from discarded fluorescent lamps.
In this study, ten bacterial strains were found to be mercury resistant after their isolation from Qatari coastal sediments. Tolerance was found to be up to 100-150 ppm for five strains. Those strai...
Healthful Seafood Consumption for Sensitive Populations
Fish can provide pregnant women with omega-3 fatty acids for fetal brain development but some fish contains high levels of mercury which is detrimental to fetal brain development. The hypo...
Influence of OCTN2 Variants on Carnitine Status and Plasma Triglycerides
The current study is part of a large multi-investigator grant to look at the pharmacogenetics of a number of membrane transporters. Previously, the investigators have recruited a cohort o...
Health Effects of Silver-Mercury Dental Fillings
The purpose of this study is to determine whether there are detectable health effects of low-level mercury exposure (from normal exposure to mercury-containing dental fillings) in the know...
Influence of Intestinal Transporter Genetic Variants on the Bioavailability of Gabapentin
The current study is part of a large multi-investigator grant to look at the pharmacogenetics of a number of membrane transporters. Previously, we have recruited a cohort of healthy volun...
Safety and Feasibility of the Mercury Expander System
To demonstrate the safety and feasibility of the Mercury Expander system and procedure to treat patients with lower urinary tract symptoms (LUTS) secondary to urinary outflow obstruction f...
Mercury Isotopes
Stable mercury atoms that have the same atomic number as the element mercury, but differ in atomic weight. Hg-196, 198-201, and 204 are stable mercury isotopes.
Mercury Poisoning
Poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of MERCURY or MERCURY COMPOUNDS.
Mercury Radioisotopes
Unstable isotopes of mercury that decay or disintegrate emitting radiation. Hg atoms with atomic weights 185-195, 197, 203, 205, and 206 are radioactive mercury isotopes.
A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
Mercury Compounds
Inorganic compounds that contain mercury as an integral part of the molecule.
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Compost bin has
The amount of money actually saved through recycling depends on the efficiency of the recycling program used to do it. The Institute for Local Self-Reliance argues that the cost of recycling depends on various factors around a community that recycles, such as landfill fees and the amount of disposal that the community recycles. It states that communities start to save money when they treat recycling as a replacement for their traditional waste system rather than an add-on to it and by "redesigning their collection schedules and/or trucks."
Container deposit legislation involves offering a refund for the return of certain containers, typically glass, plastic, and metal. When a product in such a container is purchased, a small surcharge is added to the price. This surcharge can be reclaimed by the consumer if the container is returned to a collection point. These programs have been very successful, often resulting in an 80 percent recycling rate. Despite such good results, the shift in collection costs from local government to industry and consumers has created strong opposition to the creation of such programs in some areas.
Origins of recycpling
Recycling has been a common practice for most of human history, with recorded advocates as far back as Plato in 400 BC. During periods when resources were scarce, archaeological studies of ancient waste dumps show less household waste (such as ash, broken tools and pottery)—implying more waste was being recycled in the absence of new material.
In some cases, the cost of recyclable materials also exceeds the cost of raw materials. Virgin plastic resin costs 40 percent less than recycled resin.[56] Additionally, a United States Environmental Protection Agency (EPA) study that tracked the price of clear glass from July 15 to August 2, 1991, found that the average cost per ton ranged from $40 to $60, while a USGS report shows that the cost per ton of raw silica sand from years 1993 to 1997 fell between $17.33 and $18.10.
The northwestern United States has difficulty finding markets for recycled newspaper, given the large number of pulp mills in the region as well as the proximity to Asian markets. In other areas of the U.S., however, demand for used newsprint has seen wide fluctuation.

subset: commoncrawl


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THIS photograph shows a walking day event at All Saints Church in Hindley.
It was taken in 1913.
The image shows a packed scene with men, women and children dressed up in their finery for the occasion, with some wearing hats on the day.
A flag is being held aloft in the parade and flowers are being carried by women as people watch them walk past.
Do you have an old photograph that you would like to share with us that you think would fit well on this page?
If you do, please email your picture to firstname.lastname@example.com with your name, what the image shows and what year it was taken.
Please also mention what memories you have of the scene that the photograph contains.
We will consider using pictures taken in Leigh, Atherton, Tyldesley, Hindley and surrounding areas from a different era.
To view pictures from the Wigan and Leigh Archives and Local Studies collection which features photographs from across the borough over the years visit archives.wigan.gov.uk.


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admin on June 22nd, 2010
Michigan "has" the Kirtland's Warbler, we thought that Arkansas had the Ivory-billed Woodpecker (who knows-maybe it still does), and Texas is the easiest place to see endangered Whooping Cranes. So what does Costa Rica "have"? Which birds are easier to see in its rainforests, cloud forests, montane oak forests, mangroves, and edge habitats than elsewhere? […]
Continue reading about A Dozen Birds to watch for when Birding Costa Rica part one


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If it doesn't you ain't doing it right... YES! This is a reference to Taylor Swift's 'Don't Blame Me', I'm often inspired by song lyrics, what can I say? Today I thought I'd share a little more of a lighthearted post and have a giggle at my expense, sharing a couple of stories to do … Continue reading Don't Blame Me, Love Made Me Crazy
Tag: love
Let's Talk About My Next Relationship…
Let's talk about my next relationship... Not that I plan on having one anytime soon. I just can't. First of all, I'm not in the right place emotionally / mentally to be in a romantic relationship and I certainly can't give anyone the best of me right now because I myself am not feeling like … Continue reading Let's Talk About My Next Relationship…
Feelings For My Baby
I have never known heartbreak like this, that's all I can say. I can't stop crying, scream crying even and oh my gosh it feels awful. I just want my baby with me here right now but he's not my baby, and it's not good for either of us to be together right now. I … Continue reading Feelings For My Baby
A Little Valentines Haul
Oh hey honeys! How was everybody's Valentines Day? I had my favourite Valentines Day ever ever ever so far, even though I am single I still enjoyed my day celebrating all forms of love, especially self love. The only gifts I bought this year were confectionary for my parents, some Love Hearts for my Dad … Continue reading A Little Valentines Haul
All Love Is Enough
Hello everybody! Ooh la la, it is the month of love and I'd like to take this time to remind myself and everyone reading, that there is more to love than romantic love, and all love is enough. I think more often than not, a lot of people take forms of love that aren't 'romantic' for granted. … Continue reading All Love Is Enough
A Jumble Of Thoughts
For you 🌹 I'm sorry if I've let you down I really care about you I'm sorry if that doesn't always show I'm sorry if I can't be what's best for you I hope your friends and family know how lucky they are that you choose them I hope whoever you end up with in … Continue reading A Jumble Of Thoughts
The Magic Day 3 | Magic Relationships
Hello hunnies! Today it's The Magic day 3! Which is all about magical relationships and being grateful for the relationships that you have. So for the Magic practice day 3, you need to choose three people that you are thankful for, grab some photos of them (or of the two of you together) and whilst … Continue reading The Magic Day 3 | Magic Relationships
30 Days Of Gratitude | Day 14 | Sight
Hello everybody! It's day 14 of the 30 days of gratitude challenge today, wow, I'm almost half way through! Todays prompt is sight. What sight are you thankful for today? Aw, I'm thankful for every sight! The smiles of my loved ones, the smile of my nephew which warms my heart, the sight of nature, … Continue reading 30 Days Of Gratitude | Day 14 | Sight
My Magic Moments
Hello everybody! After reading the lovely My Summer Of Magic Moments, by Caroline Roberts, a story all about appreciating the little things in life and making the most of everyday, it really got me thinking about what I consider to be my 'magic moments'. The simple, everyday things in my life that really make it … Continue reading My Magic Moments
Weekend Highlights | A World Cup Themed Dinner & Surprise Birthday BBQ's
Oh hey huns, well, it's been a while since my last weekend highlights post and today, I thought it about time I share another. The past weekend has been the loveliest family weekend, filled with lots of love and happiness, so before I ramble on for too long, let's throw it back to Friday. Friday, … Continue reading Weekend Highlights | A World Cup Themed Dinner & Surprise Birthday BBQ's


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- B405, Portland Square, Drake Circus
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Dr Tina Joshi
Lecturer in Molecular Microbiology
Faculty of Medicine and Dentistry
Lecturer in Molecular Microbiology (Teaching and Research)
Employability Co-ordinator for School of Biomedical SciencesAfter completing BSc and PhD studies at Cardiff University, I undertook several postdoctoral roles from 2012-2017 before commencement of a Lectureship at the University of Plymouth. Awarded the Hind Rattan 2018 "Jewel of India" Award from the Indian Government (Non-Resident Indian Welfare Society of India) for diasporal achievements in academia within the country of my birth- the UK.https://www.plymouth.ac.uk/news/academic-named-jewel-of-india-in-recognition-of-international-impact
Lead for Microbial Diagnostics and Infection Control Research Group
ORCID ID: orcid.org/0000-0002-5965-4055
Follow me on Twitter: @tinaljoshi
Professional membership
Fellow of the Institute of Biomedical Sciences (FIBMS)
Associate Fellow Higher Education Academy
Member of Royal Society of Biology (MRSB)
Member of Society for Applied Microbiology
Member of Microbiology Society
Member of Central Sterilising Club
Member of Healthcare Infection Society
Roles on external bodies
Teaching interests
Molecular microbiology in infectious disease, clinical microbiology, molecular diagnosis of microbial infections and bacterial genomics. This includes supervision of PG and UG students.Currently obtaining a Post Graduate Certificate in Academic Practice for teaching responsibilities.
Research interests
Described in detail on Tina's research pages:
Rapid point of care detection of Antimicrobial resistant (AMR) bacteria
Tina is an expert in the development of novel ultra-rapid point-of-care diagnostics for detection of infections (recently featured on BBC One's "The Truth about Antibiotics"). She is developing an international reputation of excellence within this area.
Tina's wealth of experience (<10 years) lies specifically in the areas of novel microwave-enhanced rapid diagnostics for microbial detection, combined with the newest developments in Molecular Biology. She has honed these multidisciplinary skills from commencement of her PhD (2008-2012) where she worked at the Institute of Fluorescence at the University of Maryland, Baltimore Country and with global experts in novel rapid diagnostics.
Areas of expertise include: Field effect transistors, thin-film transistors, application of Microwave engineering to molecular biology, aptamer design, aptamer-functionalisation of nanoparticles, microwave-accelerated metal enhanced fluorescence, microbial bioinformatics and biosensor development.
Infection Control & Microbicides
Tina has a strong interest in infection control and this research looks to understand how biocide use can affect the genomic and phenotypic properties of bacteria/spores.
Research degrees awarded to supervised students
Grants & contracts
Total Value: £1475
Sept 2018
Total Value: £17500
(Dr T. Joshi) HIS International Conference, Liverpool, Nov 2018
Sept 2018
Total Value: £750
Society for Applied Microbiology "Students into Work Grant" Miss Clare Brown
Dr. Robert Burky & Rideout Hospital, California, USA, & University of California (UCLA)
Key publications are highlightedJournals
Reports & invited lectures
Other academic activities
Patents Granted:
Baillie, L & Joshi L.T. EP2847348B1 A screening method for the detection of Clostridium difficile.
Additional information


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museum quality:16x20(40x51cm)=$99
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museum quality:30x40(76x102cm)=$199
museum quality:36x48(91x122cm)=$269
museum quality:48x72(122x182cm)=$469
All unknow artist's Paintings.
European city landscape, street landsacpe, construction, frontstore, building and architecture. 184
Beautiful European city landscape like street, constructions, frontstore, buildings and architures.Oil on canvas and painted by our talent artist.
Oil Painting ID::. 46808 Terms & ConditionsOil Painting Reproductions We Have Painted.
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china oil painting unknow artist European city landscape, street landsacpe, construction, frontstore, building and architecture. 184
Related Paintings to unknow artist :. | Oil painting in USA | Landscape with Cypresses | David Teniers II, Flemish (active Antwerp and Brussels), 1610-1690 -- The Alchemist | Anne, Lady Carleton by Michiel Jansz | John Singer Sargent--Ada Rehan | Ernest Lawson (1873-1939)-May in the Mountains | James Ensor-Flight into Egypt | Eugene Delacroix-The Women of Algiers | Michael Ancher-viggo johansen i sit atelier | Niko Pirosmani-Oil painting cloth | Piet Mondrian-Belong Conformation |
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tags: Hot Topics, Independence Day, July 4, Fourth of July
Ten Myths for the Fourth of July By Ray Raphael Top 5 Myths About the Fourth of July By Rick Shenkman Old Glory: Patriotic Symbol? By Rick Shenkman Frederick Douglass: What to the Slave Is the Fourth of July? July 4, 1965: Gay protests held in Philadelphia Marist Poll reveals ignorance of July 4th history (7-5-11) Tea party gatherings on the Fourth mix the educational and the patriotic (7-5-10) NJ Plan to Laud Declaration Signers Fizzles (7-4-07) Independence Daze: A History of July Fourth [podcast 53 min] (6-1-09) The Hidden Racist History of the National Anthem By Jason Johnson (7-4-16) Did a Fear of Slave Revolts Drive American Independence? By Robert G. Parkinson (7-4-16) Thomas B. Slaughter: July 4th Quiz: Was the Revolution Caused by a Misunderstanding Over a Word? (6-30-14) Thomas Fleming: Channelling George Washington: The Missing Word in the Declaration of Independence (7-2-12) Ira Chernus: Why All the Fireworks on the Fourth? (7-2-12) Hsuan L. Hsu: Is Independence Day a Radical Holiday? (7-2-12) Thomas Fleming: Channelling George Washington: The Revolution that Changed the World (7-3-11) Jim Cullen: The Declaration of Independence and the American Dream (6-29-11) Thomas Fleming: Channelling George Washington: The Glorious Fourth!(8-16-10) Joel Richard Paul: How We Really Won Our Independence (7-5-10) Walter Russell Mead: London Fourth (7-5-10) Wade Graham: Jefferson: Founding Father and Connoisseur (7-4-10) William Marina: Reflecting on July 4, and the Meaning of the American Revolution Today (7-4-09) Carl M. Cannon: Frederick Douglass' July 4 Challenge Answered by Obama's Election (7-3-09) Adam Freedman: Independence, British-Style (7-3-09) Kathleen DuVal: Life, Liberty and Benign Monarchy? (7-3-09) Ray Raphael: Some Tips for Celebrating the Fourth (7-2-09) Anne Pastore: "What to the Slave is the Fourth of July?" (6-27-09) Rick Shenkman: Why Is the Flag so Important? (7-13-08) Black Founding Fathers: An Interview with Richard S. Newman (6-29-08) Richard S. Newman: Review of James A. Colaiaco's Frederick Douglass and the Fourth of July (2007) (5-23-08) Roderick T. Long: Is the Declaration's Preamble Irrelevant? (7-4-07) Howard Zinn: Patriotism & The Fourth of July (7-5-06) David Blight: Frederick Douglass's Great 4th of July Oration (7-4-05) David Waldstreicher: The Invention of the Fourth of July (6-18-05) William Loren Katz: Why Blacks Used to Celebrate July 5th (7-3-04) Timothy Walch: Why Can't We See the Declaration of Independence? (6-30-03) Robert Jensen and Rahul Mahajan: What Are We Celebrating on the Fourth of July? (7-9-02) William C. Kashatus: We Remember the Wrong Tom on July Fourth (7-5-02)
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tags: Hot Topics, Independence Day, July 4, Fourth of July
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- Will Apollo Nostalgia Help NASA Get Its Artemis Moon Money?
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- How Accurate is HBO's Chernobyl? Experts Weigh In
- Anthony Price, British author of thrillers with deep links to history, dies at 90
- Students and Parents Push for Better Textbooks to Help Fight Hate and Stereotypes
- CSIS destroyed secret file on Pierre Trudeau, stunning historians
- Truman Library Announces $25 Million Transformation


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Phosphatidyl Serine is a phospholipid which is presented in a capsule which provides 200mg of phospholipids from lecithin
- Provides 200mg of phospholipids from lecithin
Soy Lecithin (Glycine max. L.Merr Bean providing Phosphatidylserine), Capsule Shell (HPMC), Anti-Caking Agents (Silicon Dioxide & Magnesium Stearate).
- Not suitable to be taken in conjunction with mood modifying drugs or sleeping pills
- If you are under medical supervision, please consult a doctor before use
- This product should not be used as a substitute for a varied and balanced diet and healthy lifestyle
- Do not exceed the stated recommended daily intake
- Do not purchase if the seal is broken
- Keep out of reach of children
- Store below 25°C in a dry place away from direct sunlight and heat
All orders placed via this website will be managed by our distribution partner, CLF Distribution, on our behalf. You will receive email confirmation letting you know when your order has been received, and when the order is being processed, and then shipped.
Which courier will deliver my order?
All UK and EU orders are shipped using our preferred couriers, DPD and the Royal Mail. The Royal Mail deliveries can take place between Monday and Saturday, whilst DPD typically deliver Monday to Friday.
When will my order be despatched?
Orders placed before 10am on working days (Monday to Friday) will be processed and despatched by CLF Distribution the same day (excluding bank holidays). All orders placed over the weekend will be despatched on the following Monday. Once the order has been despatched you will receive tracking information from the relevant courier. Please ensure that you have the order delivered to an address where someone is available to sign for the delivery.
Biocare Phosphatidyl Serine 30 Capsules


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How to view, analyze and export responses
If you are looking for a step by step guide on how to view, analyze, and export responses, you have come to the right place. In this tutorial, we will assume that there was already a form created and that there were multiple responses for that form. We will look at how Wispform can allow you visualize these responses.
Step 1: Go to response page
Upon logging into the website, you will be able to see your forms and how many responses there are. In the diagram below, you can see that there are eleven responses for the user research form. Click on the first button to go to the response page for that form.
Step 2: View your responses in a spreadsheet view
The first response page that you will land on is the spreadsheet view. You will be able to see your questions in the top row and each row below that represents a unique response. If the response for a particular question is too long, you can increase the width of each column by holding down and dragging the top cell of that particular column.
Step 3: Perform actions in the spreadsheet view
In the toolbox near the top, there are a list of actions that you can perform. These include filter, delete, color and email on the left hand side. You can filter out particular responses based on the answer for each question. If you select the rows by clicking the empty square to the left of each row, you can delete the response on add a color to the response. Coloring the response is a great way for you to organize your long list of responses. If you are on the premium tier, you can also use the email function to send a message to any responder who have filled in their email using the email question type. On the right, you will find the sort, export, and share function. Unfortunately, we do not yet support share.
Step 4: Export as PDF (Premium Feature)
If you are on the paid plan, you can will be able to select a single or multiple response and download them in a pdf format. This will not only help you share your responses with other people but also help you clearly view responses that are a little longer to read in the grid view.
Step 5: View your responses in summary view
On the left, you can navigate to the summary page for your responses. We are still working on the list view so there will be nothing if you try to click on it. Inside the summary page, you can see the metrics for number of responses, number of page views for the form, completion rate and the average time for a responder to complete the response.
Step 6: View summary diagrams
For questions of the type multichoice, yes/no, dropdown, and rating, you can see a summary of the responses in the diagrams below the summary metrics. These can be helpful if you want to quickly tally up the responses for reporting purpose.
Thanks for patiently going through this tutorial. If you are facing any issue or have any question, feel free to use the chat box on the bottom right corner of this page. We are always happy to hear from you!
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Name: The silent governess by julie klassen
File size: 727mb
Language: English
Rating: 8/10
The Silent Governess has ratings and reviews. Kay said: I noted while I was reading that this book was like vanilla pudding with vanilla spr. The Silent Governess. By Julie Klassen. Find & buy on. In midth century Britain, an imminent threat causes Olivia Keene to flee her home, separating her from. 20 Jan - 8 min - Uploaded by WeeklySarahB No, I didn't forget I was just unable to post. Sorry it's a day late.
Believing herself guilty of a crime, Olivia Keene flees her home, eventually stumbling upon a grand estate where an elaborate celebration is in progress. But all. 1 Jan The Paperback of the The Silent Governess by Julie Klassen at Barnes & Noble. FREE Shipping on $25 or more!. The Silent Governess by Julie Klassen - book cover, description, publication history.
Moving, mysterious, and romantic, The Silent Governess takes readers inside the intriguing life of a nineteenth-century View more products by Julie Klassen. 29 Jul With the stunning prose and engaging characters of The Silent Governess, Christy Award finalist Julie Klassen whisks listeners away to. The Silent Governess is a Fiction Paperback by Julie Klassen. The Silent Governess is about FICTION ROMANCE. Purchase this Paperback product online from. Listen to The Silent Governess audiobook by Julie Klassen. Stream and download audiobooks to your computer, tablet or mobile phone. Bestsellers and latest. 8 Nov My review of The Silent Governess by Julie Klassen. Historical Fiction. Historical Romance.
Lovers of regency romance and Jane Austen novels need look no further than Julie Klassen's The Silent Governess for their next foray into the intriguing. Julie Klassen is an American author of Regency romance novels. She is the winner of several Lady of Milkweed Manor (); The Apothecary's Daughter (); The Silent Governess (); The Girl in the Gatehouse (); The Maid of. 18 Jun One of the more popular genres in the Christian fiction realm is historical fiction. ' The Silent Governess ' by Julie Klassen fits very nicely into that. I honestly can't think of a single thing to write about that I didn't like in The Silent Governess. It was the first I read by Julie Klassen and by far my favorite of her.


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the world pyrometallurgy copper brand
SKY stone crushing equipment is designed to achieve maximum productivity and high reduction ratio. From large primary jaw crusher and impact crusher to cone crusher and VSI series for secondary or tertiary stone crushing.
Related Information:
Plasma Furnaces in Africa - pyrometallurgy.co.za
INTRODUCTION Interest in the application of plasma technology in Africa developed in the late 1970s, as a result of the perceived benefits of being able to process ...Read More
Electropaedia History of Science and Technology ...
The history of technology, history of science, history of inventions, the scientific revolution, the industrial revolution, the internet, space, communications ...Read More
Zinc - Wikipedia
Zinc is a chemical element with the symbol Zn and atomic number 30. It is the first element in group 12 of the periodic table. In some respects zinc is chemically ...Read More
Conferences and Meetings on Mining & Mineral Processing
Scientific Conference Calendar of Conferences and Meetings on Mining & Mineral ProcessingRead More


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Fishes become pessimistic and heartbreak when they are torn apart from their true loved ones, researchers think
- Female cichlids were sad and madly in love after their chosen partner was removed
- They were less likely to be interested in food and would probably not reproduce
- Research shows that people are not the only species who get attached to a loved one
Humans are not the only species whose mental state is affected when they lose their loved one.
Female cichlids, a type of monogamous fish that mainly live in South America, become depressed and madly in love when their partner is removed and placed with a non-preferred male partner, a new study has found.
Researchers came to this conclusion after the female fish took longer to examine boxes that contained food or were empty, and which showed symptoms of apathy.
Female cichlids, a type of fish that mainly resides in South America, become depressed and madly in love when their partner is removed and placed with a non-preferred male partner
In what is believed to be a first-of-his-kind study, researchers say they have found that fish can form an attachment to sexual partners.
Through a series of cognitive tests, they discovered that female fish are more likely to be a & # 39; half-full & # 39; mental state if they stayed with their chosen partners.
Moreover, they sprayed faster and tended more often to their eggs.
The study, published Tuesday in the Proceedings journal of the Royal Society B, was conducted by researchers at the University of Burgundy in Dijon, France.
It is also believed to be the first study to show that non-human species can also form attachments to sexual partners.
& # 39; As far as we know, it is the very first demonstration of emotional ties between partners in non-human species & # 39 ;, said Francois-Xavier Dechaume-Moncharmont, one of the co-authors of the study Inside Science.
To prove this hypothesis, the researchers conducted a series of cognitive tests in a group of 33 female cichlids.
Over the course of two weeks, they carefully studied how the behavior of the female fish changed when they were combined with a male fish that they had not picked themselves.
When women were paired with a male fish they preferred, they were released sooner, tended to their eggs, and were more likely to look at their surroundings with a & # 39; half full & # 39; perspective.
A female fish, on the other hand, which was accompanied by a non-preferred male fish, was less likely to spawn.
Scientists then gauged the mood of the female fish with a new series of experiments.
Over the course of two weeks, researchers carefully examined how the behavior of the female fish changed when they were combined with a male fish that they had not plucked themselves
They placed two different types of containers in the aquarium tent: the ones with a black lid that were empty and another with a white lid that contained a treat.
Over time, the fish had to learn by trial and error which containers had a treat and which did not.
Researchers discovered that women who accompanied the male they rejected either stopped studying the containers or did not examine them at all.
This claims that women who have been torn away from their true love are more likely to have a & # 39; pessimistic prejudice & # 39; or take on a depressive view.
In the meantime, their female counterparts staying with their chosen husbands soon discovered the white containers, again showing that half-full perspective of glass.
& # 39; When we remove the female's partner, she exhibits pessimistic behavior, & # 39; Dechaume-Moncharmont told Inside Science.
& # 39; We demonstrated in this study that in the sexual context, the presence or absence of the partner can influence the emotion of the woman. & # 39;
People joking about having the memory of a goldfish may need to think again after scientists discover that fish can remember for up to a week or two.
Canadian researchers trained fish to find food before they were removed from the tank for 12 days.
When the fish were later reintroduced, motion-tracking software revealed that they could identify the precise location of the food.
The study looked at African Cichlids, a popular aquarium species that has previously been shown to exhibit complex behaviors, including aggression.
Based on the assumption that they would be able to perform advanced memory tasks, each fish was trained to enter a certain zone of an aquarium to be fed, with each training lasting twenty minutes.
After three days the fish got a rest period of 12 days.
They were later reintroduced into their training arena and their movements were recorded with movement software.
This software revealed that the fish returned to where it found food.
Scientists believe that the fish recalled previous training experiences and were able to reverse this association after further training sessions where food reward was associated with another stimulus.
. [TagsToTranslate] Dailymail


text:
Date Posted:
May 10, 2019
Closing Date:
Jun 30, 2019
Job Status:
Full-Time Permanent
Social Science, education, government & religion
Hours per Week:
How to Apply:
Please apply by emailing your resume to firstname.lastname@example.com
Looking for full-time educators, both RECEs and Educator Assistants. Must have valid first aid/CPR and a current vulnerable sector check.
Owen Sound


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New Jobs at Delek Refinery to Pay $90,000 on Average
Delek US Holdings, Inc. on Thursday reported that it plans more enhancements to its refinery in Krotz Springs, La., and the company expects to create 30 new direct jobs as a result that will pay an average annual salary of $90,000, plus benefits.
According to a statement from the Louisiana Office of the Governor, Delek US will embark on a series of projects over the next five years at Krotz Springs that include infrastructure improvements, facility construction and renovations and new machinery and equipment. The company recently finished a $138 million project to add an alkylation facility at the 74,000-barrel-per-day refinery, which is located along the Atchafalaya River approximately 40 miles west of Baton Rouge.
"That Delek is announcing major new investments in facilities and jobs in Krotz Springs less than a month after the completion of the company's largest-ever capital project is a testament to our faith in the refinery and the team that runs it," Uzi Yemin, president and CEO of Delek US, said in the written statement.
Yemin, a native of Israel, and Louisiana Gov. John Bel Edwards met during an Oct. 2018 trade mission to Israel and their talks facilitated the latest project, according to Edwards' office. Moreover, the written statement notes that Delek US will receive a performance-based grant of up to $7.5 million over four years from the Louisiana Economic Development (LED) agency and will likely take advantage of the state's industrial tax exemption program.
"This initiative at the Delek US refinery in Krotz Springs builds on Louisiana's role as energy leader in the U.S.," stated Edwards, a Democrat who is running for re-election this fall. "These projects will create new high-paying jobs for our Acadiana Region, and we look forward to Delek's continued growth and success in St. Landry Parish."
Delek US reportedly also considered other refineries it owns in Texas and Arkansas for the project. The Krotz Springs refinery, built in 1980, produces gasoline, diesel fuel, petrochemicals and other products. The project will increase the total direct workforce at the refinery to 230, according to LED. Moreover, the agency estimates the investment will spur the creation of 48 indirect jobs.
Generated by readers, the comments included herein do not reflect the views and opinions of Rigzone. All comments are subject to editorial review. Off-topic, inappropriate or insulting comments will be removed.
Senior Editor | Rigzone
- US Oil Production Hits New All Time High
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- OPEC+ Cut Extension Highly Likely
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- $15B Deal Gives CP Chem Leading HDPE Position
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- Texas Drillers Resort to Pumping Gas Down Wells
- Fmr Exxon CEO Tillerson Reflects on White House


text:
Alexander Keith's Brewery#8 in Best Things To Do in Halifax
Key Info
- 3.5Value
- 4.0Facilities
- 4.0Atmosphere
Founded in 1820, Alexander Keith's Brewery is one of the oldest commercial breweries in North America. The brewery is named for a Scottish immigrant who devoted his life to brewing his beer. Today, the brewery still runs on Keith's values, creating flavorful ales and generously providing visitors with a relaxed, social experience.
The brewery offers booze-enthusiasts hour-long guided tours of the facility, led by actors decked out in 19th-century garb. Once the tour is over, you're welcome to sample some of Keith's most popular brews, such as the India Pale Ale at the Stag's Head Tavern. Keep in mind that there are non-alcoholic beverages available, too. One TripAdvisor user describes the experience: "We were entertained with song and merriment … and we all felt that it was a great tour and well worth the visit."
Alexander Keith's Brewery sits in downtown Halifax about a block and a half south of the Maritime Museum. Tours are offered every day between June and October, and on Fridays, Saturdays and Sundays during the rest of the year (times vary depending on the season). The 55-minute tour costs $16 CAD ($16 USD) for adults with discounts for seniors and children. For more information, check out the brewery's website.
More Best Things To Do in Halifax
#1 Historic Properties Wharf
To sample historic Halifax, spend a few hours perusing the Historic Properties. Overlooking the harbor from its city-center locale, this neighborhood retains much of its original fin-de-siècle architecture. The historic buildings that once acted as shipping warehouses and privateers' headquarters now house the lively Harbourside Market, numerous boutiques, souvenir shops and several rowdy brewpubs.
The majority of Halifax visitors and residents say that this quaint neighborhood is a must-see for first-time tourists. As one Yelp.com user (a Halifax resident) says: "It's a total tourist draw, and one of the places that is absolutely required visiting … whether you're 'from here' or 'from away.'"
Explore More of Halifax
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Holly JohnsonJune 13, 2019
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Holly JohnsonJune 13, 2019


text:
Welcome To The EA Library Blog
The dynamic, diverse and dizzyingly active centre of the school.
Connecting you with information, events, activities, banter, support and more.
The library is literally a great place to be!
Mrs Toonen, our librarian, welcomes you to our library, which is a vital part of EA.
Elgin Academy's First-Ever Comic Con was on 20 June.
This event was an epic event!
There were happy faces as everyone left and sad ones too, that it was all over.
From the team behind our first-ever Comic Con – Mr Clark, Mrs Bodiam and Mrs Toonen – a huge thank you to all who visited and who participated in the event.
Thanks to partners El-Con, Waterstones Elgin and Yeadon's of Elgin.
A huge thank you to our school partners: our Art, Drama and Home Economics departments.
Thanks to all staff and pupils for supporting the event.
Mrs Toonen was The CILIPS Library and Information Professional of the Year 2018!
Read the article on Mrs T by clicking the link below:
"The following is a guest post by Shelagh Toonen as part of our focus on members and their sectors"


text: On Tue, May 24, 2016 at 02:12:19PM -0700, Tai Tri Nguyen wrote: > It's been weeks. > I just want to ping again if you have any more comments on this patch set? We seem to have reached a stalemate whereby: - The devicetree maintainers don't agree with your binding - You don't agree with them - I won't merge the patch without their ack so I guess you either need to try harder to convince them about the index-based binding, or bite the bullet and fix it to make them happy. Will


text:
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Though this hybrid has some sativa in its lineage, Royal Chemdog is a true indica at heart. A knockout cross between Chemdawg 91 and Deadhead OG, Royal Chemdog provides consumers with a relaxing buzz, if a bit cerebral. Royal has inherited the classic diesel taste of the Chemdawg family, yet features a creamy lemon-lime twist, giving this strain a unique and delicious aroma. First cultivated in Washington State, this strain is a must-try for patients experiencing pain and stress.
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text:
Qatari FM Sheikh Mohammed bin Abdulrahman al Thani urges both sides to find a compromise and begin negotiations, warns against imposing US-led "deal of the century" on the Palestinians.
The Naksa or "the day of the setback" refers to the annual commemoration of the 1967 war in which Israel invaded Gaza, the West Bank and east Jerusalem.
Solidarity will not bring justice for the Palestinians at a time when they have been abandoned by their neighbours.
Protest marches in Iran, Iraq, Syria, Pakistan, India, occupied West Bank, disputed Kashmir, and several other places show solidarity for Palestinians.
President Donald Trump's son-in-law Jared Kushner hopes to drum up support for the economic aspects of his "deal of the century," a controversial backchannel plan to reach peace between Palestinians and Israelis.
Addressing the UN Security Council, US adviser Jason Greenblatt said UNRWA was a "bandaid" and that it was time to hand over services assured by the UN agency to countries hosting the Palestinian refugees and NGOs.
Experts do not think that the Bahrain "economic workshop" could produce anything good to address the Palestinian conflict except galvanising regional cooperation among Israel's Arab allies.
TRT World interviewed Sophia and Georgia Scott about their thoughts and ideas behind the documentaries they produce.
A member of the forgotten African-Palestinian community, Mahmoud Jiddah was born in Jerusalem around the time of the Nakba. He grew up witnessing the takeover of Palestine and joined in the resistance against Israel's occupation of his home.
As they commemorate the Nakba, or 'catastrophe', Palestinians see the UNRWA as a vital ingredient in the struggle for freedom, justice and equality.
More than 70 years later, Palestinians still gather to mark the day in which tens of thousands of people were forced from their homes during the war that led to the creation of the State of Israel in 1948.
Leaked plan to end the Israel-Palestine conflict by the Trump administration will entrench the occupation and perpetuate the economic exploitation of Palestinians.
Subscribe to our Youtube channel for all latest in-depth, on the ground reporting from around the world.
Copyright © 2019 TRT World.


text: Ex Parte FLANAGAN et alpicture_as_pdfDownload PDFprintPrintemailEmaillistCiting casesmore_horizprintPrintemailEmaillistCiting casesmore_horizprintPrintemailEmaillistCiting casesPatent Trials and Appeals BoardMay 31, 201914024056 - (D) (P.T.A.B. May. 31, 2019)Copy CitationUNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE FIRST NAMED INVENTOR 14/024,056 09/11/2013 74739 7590 06/04/2019 Potomac Law Group, PLLC (Oracle International) 8229 Boone Boulevard Suite 430 Vienna, VA 22182 Kristen J. FLANAGAN UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. 2011-004 lUSO 1 4398 EXAMINER LOHARIKAR, ANAND R ART UNIT PAPER NUMBER 3684 NOTIFICATION DATE DELIVERY MODE 06/04/2019 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): firstname.lastname@example.com firstname.lastname@example.com email@example.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte KRISTEN J. FLANAGAN, KEVIN McHUGH, AISLING GRANT, and PAUL MACRORY Appeal2018-002212 Application 14/024,056 1 Technology Center 3600 Before JASON V. MORGAN, HUNG H. BUI, and MICHAEL M. BARRY, Administrative Patent Judges. BUI, Administrative Patent Judge. DECISION ON APPEAL Appellants appeal under 35 U.S.C. § 134(a) from a final rejection of claims 1-12 and 19-24, all of the pending claims. We have jurisdiction under 35 U.S.C. § 6(b ). We AFFIRM. 2 1 According to Appellants, the real party in interest is Oracle International Corporation. App. Br. 2. 2 Our Decision refers to Appellants' Appeal Brief filed June 19, 2017 ("App. Br."); Reply Brief filed December 26, 2017 ("Reply Br."); Examiner's Answer mailed October 24, 2017 ("Ans."); Final Office Action mailed January 11, 2017 ("Final Act."); and original Specification filed September 11, 2013 ("Spec."). Appeal2018-002212 Application 14/024,056 STATEMENT OF THE CASE Appellants' invention is directed to "a computer system that provides electronic commerce catalog pricing," i.e., an e-commerce catalog pricing "system that prices products of a catalog of an e-commerce web site." Spec. ,r,r 1, 4. According to Appellants, "the pricing system allows a product to be specified as 'non-discountable' to assure that the product is not inadvertently discounted as part of a promotion or other mechanism." Id. ,r 11. Claims 1, 7, and 19 are independent. Independent claim 1, reproduced below, is exemplary of the subject matter on appeal. 1. A non-transitory computer readable medium having instructions stored thereon that, when executed by a processor, cause the processor to price products of a product catalog of an e-commerce web site, the pricing comprising: designating a first product in the product catalog as non- discountable, the product catalog providing product information to users of the e-commerce web site; during interaction by any of the users of the e-commerce web site with a user interface corresponding to the e-commerce web site, receiving a request to discount the first product as part of a first promotion in conjunction with a purchase of one or more products in the product catalog; and preventing the discount of the first product in response to accessing the product catalog, the preventing comprising generating a message on the user interface in response to a selection of the first product in response to an interaction with the user interface, the message indicating that the first product is not discountable and the message displayed before generating a shopping cart, the preventing further comprising not including the first product in an order total within the shopping cart when determining the discount within the shopping cart. App. Br. 11 (Claims App.). 2 Appeal2018-002212 Application 14/024,056 REJECTION The Examiner rejected claims 1-12 and 19-24 under 35 U.S.C. § 101 because the claimed invention is directed to an abstract idea without significantly more. Final Act. 2--4, 6. ANALYSIS In rejecting claims 1-12 and 19-24 under 35 U.S.C. § 101, the Examiner determines these claims are directed to "designating a first product as non-discountable" and "preventing the discount of the first product" which fall into multiple categories of abstract ideas, including: (1) "certain methods of organizing human activity," and (2) "mental processes [that could be performed in the human mind or by a human using a pen and paper]." Ans. 4. According to the Examiner, these claims also include limitations that are analogous or similar to: (1) concepts of comparing new and stored information and using rules to identify options as discussed in SmartGene; (2) concepts of using categories to organize, store, and transmit information as discussed in Cybeifone; and (3) concepts of delivery of free content in exchange for viewing ads as discussed in Ultramercial. Final Act. 2; see SmartGene, Inc. v. Advanced Biological Labs., SA, 852 F. Supp. 2d 42 (D. D.C. 2012), ajf'd, 555 F. App'x 955 (Fed. Cir. 2014) (holding that claims directed to "comparing new and stored information and using rules to identify medical options" are not patent-eligible); Cyberfone Sys., LLC v. CNN Interactive Grp., 558 F. App'x 988, 992 (Fed. Cir. 2014) (holding that claims directed to "using categories to organize, store, and transmit information is well-established ... the idea of collecting information in 3 Appeal2018-002212 Application 14/024,056 classified form, then separating and transmitting that information according to its classification" are not patent-eligible); Ultramercial, Inc. v. Hulu, LLC, 772 F.3d 709, 715-16 (Fed. Cir. 2014) (holding that claims directed to "showing an advertisement before delivering free content" are not patent- eligible ); see also CyberSource Corp. v. Retail Decisions, Inc., 654 F.3d 1366, 1372 (Fed. Cir. 2011) (holding that claims directed to "[a] method ... [that] can be performed in the human mind, or by a human using a pen and paper" are not patent-eligible). The Examiner also determines the claims fail to amount to "significantly more than the judicial exception" or contain an "inventive concept" because the additional elements recited: (1) "represent generic computer components that operate using well-understood, routine, and conventional functions" (Final Act. 3) and (2) do not improve the functioning of a computer or improve any other technology. Ans. 5. Appellants argue independent claims 1, 7, and 19 as a group. See App. Br. 3-7. We select independent claim 1 as exemplary of the group. See 37 C.F.R. § 41.37(c)(l)(iv) (2016). Claims 2-6, 8-12, and 20-24 stand or fall with claim 1 (see id.). Legal Framework To determine whether claims are patent eligible under§ 101, we apply the U.S. Supreme Court's two-step framework articulated in Alice Corp. v. CLS Bankint'l, 573 U.S. 208 (2014). First, we determine whether the claims are directed to a patent-ineligible concept: laws of nature, natural phenomena, and abstract ideas. Id. at 216-17. If so, we then proceed to the second step to consider the elements of the claims "individually and 'as an ordered combination"' to determine whether there are additional elements 4 Appeal2018-002212 Application 14/024,056 that "'transform the nature of the claim' into a patent-eligible application." Id. at 217. In other words, the second step is to "search for an 'inventive concept'-i.e., an element or combination of elements that is 'sufficient to ensure that the patent in practice amounts to significantly more than a patent upon the [ineligible concept] itself."' Id. ( alteration in original). The Federal Circuit has described the Alice step-one inquiry as looking at the "focus" of the claims, their "character as a whole," and the Alice step-two inquiry as looking more precisely at what the claim elements add-whether they identify an "inventive concept" in the application of the ineligible matter to which the claim is directed. See Elec. Power Grp., LLC v. Alstom S.A., 830 F.3d 1350, 1353 (Fed. Cir. 2016); Enfzsh, LLC v. Microsoft Corp., 822 F.3d 1327, 1335-36 (Fed. Cir. 2016); Internet Patents Corp. v. Active Network, Inc., 790 F.3d 1343, 1346 (Fed. Cir. 2015). Because there is no single definition of an "abstract idea" under Alice step 1, the Federal Circuit has adopted the common law, analogy-driven approach (i.e., the "analogous claim" test) to determine whether a claim is directed to an abstract idea, and has instructed us "to examine earlier cases in which a similar or parallel descriptive nature can be seen-what prior cases were about, and which way they were decided." Amdocs (Israel) Ltd. v. Openet Telecom, Inc., 841 F.3d 1288, 1294 (Fed. Cir. 2016) (citing Elec. Power Grp., 830 F.3d at 1353-54). The Office sought to apply the Federal Circuit's common law "analogous claim" test in the aftermath of Alice (see USPTO Memorandum, July 2015 Update: Subject Matter Eligbility, 3 (July 30, 2015), https://www. uspto.gov/sites/default/files/documents/ieg-july-2015-update.pdf ("a claimed concept is not identified as an abstract idea unless it is similar to at least one 5 Appeal2018-002212 Application 14/024,056 concept that the courts have identified as an abstract idea")). But recently, the Office concluded that having examiners seek analogous claims had since become impractical and unpredictable in light of the growing body of Federal Circuit precedent. Thus, the Office has issued a new § 101 Memorandum interpreting governing case law and establishing a framework for patent-eligibility analysis under Alice and§ 101 effective as of January 7, 2019. See USPTO, 2019 Revised Patent Subject Matter Eligibility Guidance, 84 Fed. Reg. 50, 52 (Jan. 7, 2019) ("Revised Guidance"). Revised Guidance In the Revised Guidance, the Office has identified, for purposes of clarity, predictability, and consistency, key concepts identified by the courts as abstract ideas to explain that the "abstract idea" exception. According to the Revised Guidance and under Alice step 1 (abstract idea), we first look to whether the claim recites: ( 1) any judicial exceptions, including certain groupings of abstract ideas (i.e., [i] mathematical concepts, [ii] mental processes, or [iii] certain methods of organizing human activity such as a fundamental economic practice or managing personal behavior or relationships or interactions between people); and (2) additional elements that integrate the judicial exception into a practical application (see Manual of Patent Examining Procedure ("MPEP") §§ 2106.05(a}-(c), (e}-(h)). 3 See Revised Guidance, 84 Fed. Reg. at 51-52, 55, Revised Step 2A, Prong One (Abstract Idea) and Prong Two (Integration into A Practical Application). 3 All references to the MPEP are to the Ninth Edition, Revision 08-2017 (rev. Jan. 2018). 6 Appeal2018-002212 Application 14/024,056 A claim that integrates a judicial exception into a practical application applies, relies on, or uses the judicial exception in a manner that imposes a meaningful limit on the judicial exception, such that the claim is more than a drafting effort designed to monopolize the judicial exception. See Revised Guidance, 84 Fed. Reg. at 54. When the judicial exception is so integrated, then the claim is not directed to a judicial exception and is patent eligible under § 101. Id. "Integration into a practical application" requires an additional element or a combination of additional elements in the claim to apply, rely on, or use the judicial exception in a manner that imposes a meaningful limit on the judicial exception, such that the claim is more than a drafting effort designed to monopolize the exception. Id. at 53, 55. For example, limitations that are indicative of "integration into a practical application" include: 1) Improvements to the functioning of a computer, or to any other technology or technical field-see MPEP § 2106.05(a); 2) Applying the judicial exception with, or by use of, a particular machine-see MPEP § 2106.05(b ); 3) Effecting a transformation or reduction of a particular article to a different state or thing-see MPEP § 2106.05(c); and 4) Applying or using the judicial exception in some other meaningful way beyond generally linking the use of the judicial exception to a particular technological environment, such that the claim as a whole is more than a drafting effort designed to monopolize the exception-see MPEP § 2106.05(e). In contrast, limitations that are not indicative of "integration into a practical application" include: 1) Adding the words "apply it" ( or an equivalent) with the judicial exception, or mere instructions to implement an abstract idea on a computer, or merely uses a computer as a tool to perform an abstract idea-see MPEP § 2106.05(±); 7 Appeal2018-002212 Application 14/024,056 2) Adding insignificant extra-solution activity to the judicial exception-see MPEP § 2106.05(g); and 3) Generally linking the use of the judicial exception to a particular technological environment or field of use-see MPEP § 2106.05(h). See Revised Guidance, 84 Fed. Reg. at 54--55 ("Prong Two"). Only if a claim: (1) recites a judicial exception, and (2) does not integrate that exception into a practical application, do we then evaluate whether the claim provides an "inventive concept" under Alice step 2. See Revised Guidance at 56; Alice, 573 U.S. at 217-18. For example, we look to whether the claim: 1) adds a specific limitation beyond the judicial exception that is not "well-understood, routine, conventional" in the field (see MPEP § 2106.05(d)); or 2) simply appends well-understood, routine, and conventional activities previously known to the industry, specified at a high level of generality, to the judicial exception. See Revised Guidance, 84 Fed. Reg. at 56. Alice/Mayo-Step 1 (Abstract Idea) Step 2A-Prongs 1 and 2 identified in the Revised Guidance Step 2A, Prong One Turning to the first step of the Alice inquiry, we determine if the claims recite a judicial exception. Appellants argue claim 1 is not directed to an abstract idea because: (1) "the Examiner NEVER identifies 'the abstract idea as it is recited (i.e., set forth or described) in the claim"; (2) the Examiner fails to explain "why any identified abstract idea ... 'corresponds to a concept that the courts have identified as an abstract idea"'; and (3) the Examiner's reliance on SmartGene, Cybeifone, and Ultramercial is misplaced because (i) SmartGene and Cyberfone are non-precedential decisions, and (ii) Ultramercial is not related to pricing products for a 8 Appeal2018-002212 Application 14/024,056 product catalog of an e-commerce web site without discount prevention. App. Br. 3-5. At the outset, we note Appellants' arguments regarding SmartGene, Cyberfone, and Ultramercial are not persuasive and are no longer applicable because the Revised Guidance now governs all patent-eligibility analysis under Alice and§ 101 effective as of January 7, 2019. Moreover, the Examiner determines, and we agree that Appellants' claims are directed to "designating a first product as non-discountable" and "preventing the discount of the first product" are descriptive of a "certain method[] of organizing human activity," which includes fundamental economic practices, specifically, marketing, sales, and advertising (Ans. 4), as set forth in the Revised Guidance because "designating a first product as non- discountable," according to Appellants' Specification, is necessary to ensure that "the product is not inadvertently discounted as part of a promotion or other mechanism." Spec. ,r 11. Such activities are squarely within the realm of abstract ideas, like: (1) the risk hedging in Bilski v. Kappas, 561 U.S. 593 (2010); (2) the intermediated settlement in Alice, 573 U.S. at 219-22; (3) verifying credit card transactions in CyberSource, 654 F.3d at 1370; (4) guaranteeing transactions in buySAFE, Inc. v. Google, Inc., 765 F.3d 1350, 1354 (Fed. Cir. 2014); (5) distributing products over the Internet in Ultramercial, Inc. v. Hulu, LLC, 772 F.3d 709 (Fed. Cir. 2014); ( 6) determining a price of a product offered to a purchasing organization in Versata Dev. Grp., Inc. v. SAP Am., Inc., 793 F.3d 1306 (Fed. Cir. 2015); and (7) pricing a product for sale in OIP Techs., Inc. v. Amazon.com, Inc., 788 F.3d 1359 (Fed. Cir. 2015). Designating a product as non-discountable for future sale activities is also a building block of a market economy and, 9 Appeal2018-002212 Application 14/024,056 like risk hedging and intermediated settlement, is an "abstract idea" beyond the scope of§ 101. See Alice, 573 U.S. at 219--20. The Examiner also determines, and we agree, that Appellants' claims also include a mental process that could be performed in the human mind or by a human mind or using a pen and paper as the claims also require an observation or evaluation ("designating a first product in the product catalog as non-discountable"; "receiving a request to discount the first product as part of a first promotion in conjunction with a purchase of one or more products in the product catalog;" and "preventing the discount of the first product in response to accessing the product catalog."). That is, before computers were used, a marketing department of a company would designate certain products as "non-discountable" and notify a customer if those products are not discountable when the customer was ready to make payment. Mental processes remain unpatentable even when automated to reduce the burden on the user of what once could have been done with pen and paper. See CyberSource, 654 F.3d at 1375 ("That purely mental processes can be unpatentable, even when performed by a computer, was precisely the holding of the Supreme Court in Gottschalk v. Benson."); see also In re Salwan, 681 F. App'x 938, 941 (Fed. Cir. 2017) (claims for organizing patient health information, transferring patient health information to a patient network, and billing insurance companies held patent-ineligible). Thus, under Step 2A, Prong One, we agree with the Examiner the claims fall within judicial exceptions listed in the Revised Guidance. Step 2A, Prong Two (Integration into a Practical Application) Under Prong Two of the Revised Guidance, we must determine if the claims (i.e., additional limitations beyond the judicial exception) integrate 10 Appeal2018-002212 Application 14/024,056 the judicial exception into a practical application. However, we discern no additional elements ( or combination of elements) recited in Appellants' claims 1, 7, and 19 ( e.g., a processor and storage device) that integrate the judicial exceptions into a practical application. See Revised Guidance, Revised Step 2A, Prong Two. For example, Appellants' claimed additional elements (e.g., processor and storage device) recited in claims 1, 7, and 19 do not: ( 1) improve the functioning of a computer or other technology; (2) are not applied with any particular machine ( except for a generic computer); (3) do not effect a transformation of a particular article to a different state; and ( 4) are not applied in any meaningful way beyond generally linking the use of the judicial exception to a particular technological environment, such that the claim as a whole is more than a drafting effort designed to monopolize the exception. See MPEP §§ 2106.05(a}-(c), (e}-(h). For business-centric inventions such as Appellants' invention involving designating products as "non-discountable" for sales, the "integration into a practical application" prong further requires consideration of whether the claims purport to provide "a technical[] solution to a technical[] problem" as required by the Federal Circuit's precedential decisions in (1) DDR Holdings, LLC v. Hotels.com, L.P., 773 F.3d 1245, 1257 (Fed. Cir. 2014) and (2) Amdocs (Isr.) Ltd. v. Openet Telecom, Inc., 841 F.3d 1288, 1301 (Fed. Cir. 2016). See MPEP § 2106.05(a). Appellants argue their claims, similar to the claims in DDR Holdings, are fundamentally directed to a technical solution to a technical problem that is "necessarily rooted in computer technology in order to overcome a problem specifically arising in the realm of computer networks." App. Br. 6-7 (citing DDR, 773 F.3d at 1257) (emphasis added); Ans. 2. 11 Appeal2018-002212 Application 14/024,056 Appellants' argument is not persuasive, however. Appellants' Specification and claims describe "an electronic commerce ('e-commerce') catalog pricing system" that enables a user to designate a product as "non- discountable" for sales in order to ensure that "the product is not inadvertently discounted as part of a promotion or other mechanism." Spec. ,r 11. "[D]esignating a ... product in the product catalog as non- discountable" is a fundamental economic practice long prevalent in our system of commerce. Such a method of "designating a ... product in the product catalog as non-discountable" does not provide a technical solution to a technical problem unique to the Internet, i.e., a "solution ... necessarily rooted in computer technology in order to overcome a problem specifically arising in the realm of computer networks." DDR, 773 F.3d at 1257. Nor does Appellants' invention entail, like Amdocs, any "unconventional technological solution ( enhancing data in a distributed fashion) to a technological problem (massive record flows which previously required massive databases)" and "improve the performance of the system itself." Amdocs, 841 F.3d at 1300, 1302. Instead, the solution proposed by Appellants is a business solution, implemented with a general purpose computer, rather than a technological solution. Thus, under Step 2A, Prong Two, we determine the judicial exception is not integrated into a practical application under the Revised Guidance Alice/Mayo-Step 2 (Inventive Concept) Step 2B identified in the Revised Guidance In the second step of the Alice inquiry, Appellants argue claims 1, 7, and 19 contain an "inventive concept" because: (1) "elements of the present claims are nonconventional and non-obvious" (i.e., claims contain allowable subject matter (see Final Act. 7)); (2) pending claims recite a 'non- 12 Appeal2018-002212 Application 14/024,056 conventional and non-generic arrangement of known, conventional pieces" similar to the claims in Bascom Global Internet Servs., Inc. v. AT&T Mobility LLC, 827 F.3d 1341 (Fed. Cir. 2016); and (3) "the claims do not preempt an abstract idea." App. Br. 7-9 (emphasis omitted). Appellants' arguments are not persuasive. At the outset, we note that (1) "the concept of inventiveness is distinct from that of novelty" and (2) "[t]he inventiveness inquiry of§ 101 should therefore not be confused with the separate novelty inquiry of§ 102 or the obviousness inquiry of§ 103." Amdocs, 841 F .3d at 1311. We may even assume that the techniques claimed are "[g]roundbreaking, innovative, or even brilliant," but that is not enough for eligibility. Ass 'n for Molecular Pathology v. Myriad Genetics, Inc., 569 U.S. 576, 591 (2013); accord buySAFE, Inc. v. Google, Inc., 765 F.3d 1350, 1352 (Fed. Cir. 2014). Nor is it enough for subject-matter eligibility that claimed techniques be novel and nonobvious in light of prior art, passing muster under 35 U.S.C. §§ 102 and 103. See Mayo Collaborative Servs. v. Prometheus Labs., Inc., 566 U.S. 66, 89-90 (2012); Synopsys, Inc. v. Mentor Graphics Corp., 839 F.3d 1138, 1151 (Fed. Cir. 2016) ("[A] claim for a new abstract idea is still an abstract idea. The search for a § 101 inventive concept is thus distinct from demonstrating § 102 novelty."); Intellectual Ventures I LLC v. Symantec Corp., 838 F.3d 1307, 1315 (Fed. Cir. 2016) (same for obviousness) ("Symantec"). The claims here are ineligible because their innovation is an innovation in ineligible subject matter. Their subject is nothing but "designating a first product as non-discountable" and "preventing the discount of the first product." Spec. ,r,r 1, 4, 11. An advance of that nature is ineligible for patenting. 13 Appeal2018-002212 Application 14/024,056 We also note that, as the McRO court explicitly recognized, "'the absence of complete preemption does not demonstrate patent eligibility."' See McRO, Inc. v. Bandai Namco Games Am. Inc., 837 F.3d 1299, 1315 (Fed. Cir. 2016) (quoting Ariosa Diagnostics, Inc. v. Sequenom, Inc., 788 F.3d 1371, 1379 (Fed. Cir. 2015)). "Where a patent's claims are deemed only to disclose patent ineligible subject matter" under the Alice/Mayo framework, "preemption concerns are fully addressed and made moot." Ariosa, 788 F.3d at 1379. Lastly, Appellants' reliance on Bascom is also misplaced. For example, the patent at issue in Bascom (U.S. Patent No. 5,987,606 ("Bascom '606 patent")) describes a particular arrangement of filtering software at a specific location, remote from the end-users, with customizable filtering features specific to each end user. The filtering software enables individually customizable filtering at the remote ISP server by taking advantage of the technical ability of the ISP server to identify individual accounts and associate a request for Internet content with a specific individual account. Bascom '606 patent, 4:35-38. The Federal Circuit recognized that Bascom's installation of an Internet content filter at a particular network location is "a technical improvement over prior art ways of filtering such content" because such an arrangement advantageously allows the Internet content filter to have "both the benefits of a filter on a local computer and the benefits of a filter on the ISP server" and "give[ s] users the ability to customize filtering for their individual network accounts." Bascom, 827 F.3d at 1350, 1352. According to the panel, Bascom's claims "do not preempt the use of the abstract idea of filtering content on the Internet or on generic computer components 14 Appeal2018-002212 Application 14/024,056 performing conventional activities." Id. Instead, Bascom's claims "carve out a specific location for the filtering system (a remote ISP server) and require the filtering system to give users the ability to customize filtering for their individual network accounts." Id. As such, "an inventive concept can be found in the non-conventional and non-generic arrangement of known, conventional pieces." Id. at 1350. In contrast to Bascom, Appellants' claims and Specification are directed to "a computer system that provides electronic commerce catalog pricing," i.e., an e-commerce catalog pricing "system that prices products of a catalog of an e-commerce web site." Spec. ,r,r 1, 4. According to Appellants, "the pricing system allows a product to be specified as 'non- discountable' to assure that the product is not inadvertently discounted as part of a promotion or other mechanism." Id. ,r 11. There is no evidence in the record to support the contention that Appellants' claimed system includes any non-conventional and non-generic arrangement of known, conventional components similar to Bascom. As recognized by the Revised Guidance, an "inventive concept" under Alice Step 2 can also be evaluated based on whether an additional element or combination of elements: ( 1) [ a ]dds a specific limitation or combination of limitations that are not well-understood, routine, conventional activity in the field, which is indicative that an inventive concept may be present; or (2) simply appends well-understood, routine, conventional activities previously known to the industry, specified at a high level of generality, to the judicial exception, which is indicative that an inventive concept may not be present. 15 Appeal2018-002212 Application 14/024,056 See Revised Guidance, 84 Fed. Reg. at 56. We find no element or combination of elements recited in Appellants' claims 1 and 22 that provide any "inventive concept" or add anything "significantly more" to transform the abstract concept into a patent-eligible application. Alice, 573 U.S. 208 at 221. Rather, Appellants' invention uses generically-claimed computer components ( a processor and storage device) to perform the abstract idea. As our reviewing court has observed, "after Alice, there can remain no doubt: recitation of generic computer limitations does not make an otherwise ineligible claim patent-eligible." DDR, 773 F.3d at 1256 (citing Alice, 573 U.S. at 223). As Appellants' claims recite only the using generic computer components to accomplish the identified abstract idea, the claims only limit the abstract idea to a particular technological environment. Spec. ,r,r 24, 64, 101; see MPEP § 2106.05(h). Because Appellants' independent claims 1, 7, and 19, when considered as a whole, are directed to a patent-ineligible abstract idea that do not integrate into a practical application and do not recite an "inventive concept," we sustain the Examiner's rejection of claims 1-12 and 19-24 under 35 U.S.C. § 101. DECISION The Examiner's decision rejecting claims 1-12 and 19-24 is affirmed. No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a)(l )(iv). AFFIRMED 16 Copy with citationCopy as parenthetical citation


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