text:
Please read below information from Australian health authorities followed by alternative information.
From the Australian government
Meningococcal disease is a life-threatening illness caused by a number of different strains of the bacterium Neisseria meningitidis. This bacterium, spread through coughing, sneezing or close contact with infected people, can cause septicaemia (blood poisoning) and meningitis (inflammation of the membranes around the brain and spinal cord).
Up to one in 10 patients with invasive meningococcal disease in Australia dies. Of those who survive, one in 30 has severe skin scarring or loss of limbs, and one in 30 has severe brain damage.
People with meningococcal disease can become extremely unwell very quickly. As well as causing meningitis and septicaemia – often simultaneously – meningococcal disease can lead to pneumonia (lung infection), septic arthritis, and conjunctivitis (eye infection).
Globally there are 13 strains of meningococcal disease, the most common being A, B, C, W135 and Y. The two most common strains of meningococcal disease in Australia are B and C. The meningococcal B vaccine Bexsero® is available through purchase on the private market. While infection by strains A, W135 and Y is less common in Australia, vaccination is important in older children and adults who are travelling overseas. There are vaccines available on prescription for meningococcal ACWY and meningococcal B.
In Australia, meningococcal infections caused by strain B & C are vaccine preventable in all age groups, including babies and young children. The highest rate of meningococcal disease occurs in children under five years of age, although this has decreased since the introduction of the free meningococcal C vaccine under the National Immunisation Program.
Meningococcal C vaccination is recommended as part of routine childhood immunisation. The meningococcal C vaccine is listed on the National Immunisation Program Schedule.
Source: Meningococcal Disease
The other side
The meningococcal disease vaccine "Meningococcal C" was introduced in Australia in 2003 mainly to try to reduce meningitis cases, probably due to the Hib vaccine failing to do so after being introduced 10 years earlier.
This vaccine is one of 3 vaccines now used to combat, respectively, 3 bacterial diseases that can all cause meningitis, septicaemia and pneumonia and other bacterial infections. These bacteria were deemed the most common causes of this range of conditions at the time of introduction of the respective vaccines.
The 3 bacterial diseases, the vaccine and year of introduction of the vaccine are:
- Haemophilus Infuenzae type b (Hib vaccine) – 1992-3
- Neisseria meningitidis (Meningococcal C vaccine) – 20003
- Streptococcus pneumoniae (Pneumococcal vaccine) – 2005
While these bacteria can be linked with illnesses such as meningitis, septicaemia and pneumonia, over 90% of us will play host to the range of bacteria that can cause these conditions without ever showing symptoms of any disease. We have lived with these bacteria for thousands of years and it is only in rare instances that they can make us ill.
Medicine has not sought to discover what the triggers are for turning a normally benign bacteria into a killer. Instead, its answer has been to vaccinate us against the bacteria using a shot whose side effects include suppression of our immune system, leaving us potentially more susceptible to diseases such as meningitis and septicaemia.
Disease naming and vaccine evaluation
The naming of diseases by microbe rather than by clinical symptoms is a departure from traditional disease naming, and it began during in the 1990s as pathology testing became more widely available.
A problem with evaluating the success of eradication programs of diseases named in this way is that the microbes may be wiped out by intervention measures, but that does not necessarily mean the target disease (e.g. meningitis) is wiped out. This is because other microbes can easily take the place of the ones no longer in circulation, and cause just as much disease, or even more (think of how antibiotics have bred super bugs).
Thus the only way to really evaluate success of vaccination programs for these types of diseases is to look at data for the target illness, rather than for the microbe. Despite this, health authorities continue to publish data showing reductions in notifications of cases caused by the Hib bacterium, suggesting vaccination has been a success.
Of the 3 diseases/vaccines listed above, only Hib has been used for long enough to evaluate its success, but the graphs below do show some short-term results for the other two vaccines. It appears the Hib vaccine did nothing to reduce meningitis and septicaemia, and the other two vaccines didn't help either (all-ages graphs don't show better results for the vaccines).
Graphs are from Fooling Ourselves: on the fundamental value of vaccines by Greg Beattie
Meningococcal disease
There is no long-term data yet for determining success or failure of the vaccine for meningococcal disease in Australia, in terms of the target illnesses. As there are so many strains and species of bacteria around, it would be reasonable to assume that as the bacteria are eradicated, other microbes will step up to the plate and cause just as much meningitis and so on, as long as children are susceptible.
To illustrate this point, we refer you to a letter published by two high profile Indian paediatricians in the Bulletin of the World Health Organisation in 2008, about another bacterial vaccine, the Pneumococcal disease vaccine.
They discuss the merits of the vaccine, and point out that although it may have an effect on "vaccine-serotype bacteraemic" pneumonia, it does not reduce clinical pneumonia. In other words, regardless of what is reported about the vaccine's effectiveness against the microbe, it does not reduce the amount of actual illness.
Source: Incidence of pneumonia is not reduced by pneumococcal conjugate vaccine; Sona Chowdhary, Jacob Puliyel. Bull WHO vol.86 no.10 Oct 2008
Vaccine decisions
The vaccine Meningococcal C protects against one of many strains of the bacterium Neisseria meningitidis. The commercial name for the vaccine currently given in Australia is Menitorix, and it includes both the Hib vaccine and the Meningococcal C vaccine in a single dose.
This vaccine is given at 12 months of age.
When deciding whether to vaccinate your child, it is a good idea to read product information from the manufacturers, which you can find easily with a web search. Firstly, look up the vaccination schedule for your state, to confirm the product name (in case it differs from the product named above). Then find official product information from the manufacturers – these will usually be PDFs. Menitorix is made by GlaxoSmithKline.
Also, try to get hold of a package insert from a doctor or online, if you can.
We suggest you look carefully at ingredients of the vaccines, contraindications and possible side effects. Also have a look at safety studies, and notice the number of subjects and follow-up time period.
Further reading
We suggest you get hold of this excellent book – it is available as a printed book and also as a PDF and has an emphasis on Australia. See chapter 6 for a discussion of the 3 vaccines mentioned on this page.
Fooling Ourselves: on the fundamental value of vaccines by Greg Beattie
See the following page on this website: Hib (Haemophilus influenzae type b) for more discussion of bacterial diseases.


text:
Toward a Zombie Epistemology: What it means to live and die in Cabin in the Woods
¶ 2
Leave a comment on paragraph 2 0
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.
¶ 3 Leave a comment on paragraph 3 0 Deanna Day
¶ 4 Leave a comment on paragraph 4 0 INTRODUCTION
¶ 5 Leave a comment on paragraph 5 0 Cabin in the Woods begins with fertility.
¶ 6 Leave a comment on paragraph 6 0 The movie opens in the middle of the most banal of office scenes, with two white-shirted white men futzing around in a break room. Hadley complains about his ongoing conflict with his partner over their potential child, while Sitterson extracts a coffee from a vending machine. Although Hadley and his partner are still in the process of trying to conceive, she has already begun child-proofing the house. Draping himself over a water cooler, Hadley describes it. "Dude, she did the drawers! We don't even know if this whole fertility thing is going to work, and she screwed in these little jobbies where you can't even open the drawers!"[1]
¶ 7 Leave a comment on paragraph 7 0 Sitterson waves off the "nightmare" of the drawers. "Sooner or later," he shrugs, they will be necessary; to him, Hadley's future child is an inevitability, and Hadley's partner's impulse to protect it are "natural." Hadley, on the other hand, views the whole process as a jinx. "It guarantees that we won't get pregnant. And," Hadley concludes, "it takes me about 20 minutes to get a fucking beer."
¶ 8 Leave a comment on paragraph 8 0 This scene was part of the initial pitch for Cabin in the Woods; Joss Whedon originally explained to co-writer Drew Goddard that he wanted to start the movie "with two guys in a break room, talking about fertility."[2] The film is generally described as a meta commentary on the horror movie genre, deliberately identifying and satirizing common elements of horror films to comment on audience desires. (When the seemingly inevitable zombies appear, Hadley, Sitterson, and their colleagues view them as boring and yet incredibly good at their job: "they have a 100% clearance rate.") Whedon himself describes his project as trying to figure out "why [horror] movies follow this pattern."[3] By beginning with a discussion of reproductive technologies, and continuing to focus as much on scientists and engineers as cavorting coeds, Whedon explores this question with an indictment of the real-world institutions of modern science in all of their bureaucratic, banal, and globally-destructive glory. He answers horror with science (fiction), critiquing the methods through which we make knowledge about the world.
¶ 9 Leave a comment on paragraph 9 1 What is it about us, Whedon asks, that makes us so drawn to the voyeuristic slaughter of the young? Cabin makes us reckon with the violence that feminist and queer theorists have argued is at the foundation of our social world. It dims the screen to reveal the violence that, if it were eliminated, would destroy the civilized arrangements in which we place our faith and understand our futures. The ideology of Cabin is what James Scott has described as high modernism, "a strong, one might even say muscle-bound, version of the self-confidence about scientific and technical progress…the mastery of nature (including human nature), and, above all, the rational design of social order commensurate with the scientific understanding of natural laws."[4] The workers in the cabin's control room work all year to create the perfectly ordered sacrifice, the efficient combination of supposedly deserved deaths, to keep the gods happy and ensure the survival of the rest of humanity, just as we accept a certain number of deaths and mutilations to industrial accidents, clinical experiments, or radiation exposures in order to keep the economy roiling and our civilization alive. Death for the few is "axiomatic," written so completely into the functioning of modernity that to remove it would mean death for all, the death of our future.
¶ 10 Leave a comment on paragraph 10 0 Cabin answers Whedon's questions with a far more unsettling premise than that typically used to explain away our horrific obsession. We are not answering the call of our reptilian brains, not looking to fight back against modern capitalism, not grappling with the threat of plague or radiation or chemical warfare. We want to watch teenagers being fed to zombies, selfishly, because we know that our own lives depend on it.
¶ 11 Leave a comment on paragraph 11 0 WHAT DOES IT MEAN TO DIE?
¶ 12 Leave a comment on paragraph 12 1 Queer theorists have begun to take a critical stance towards a dominant politics in contemporary western culture that makes appeals based on the projected needs of the future. Often, this future becomes ideologically embodied in the form of an idealized child. As Lee Edelman describes, our politics is in the service of a child who "remains the perpetual horizon…the fantasmatic beneficiary of every political intervention." For that Child, our entire conservative politics "works to affirm a structure, to authenticate social order, which it then intends to transmit to the future in the form of its inner Child."[5] Edelman defines this drive as society's overwhelming "reproductive futurism."
¶ 13 Leave a comment on paragraph 13 1 In her work, Judith Halberstam links such a reproductive futurism to the goals that are often espoused in the name of society's hypothetical future children. She writes, "success in a heteronormative, capitalist society equates too easily to specific forms of reproductive maturity combined with wealth accumulation."[6] Such success is specifically cast as a kind of prepared hopefulness where, by shoring up particular family and community structures with financial entanglements, we might be able to ward off whatever it is that is at this moment impending: global economic collapse, the death of the American family, etc. The imperative to work for the survival of future generations, rather than for happiness in the moment, makes it not only possible but a seeming inevitability that life must be for many people an exercise of sacrifice.
¶ 14 Leave a comment on paragraph 14 0 Hadley and Sitterson's opening conversation immediately establishes that Cabin in the Woods recognizes this worldview. Hadley's frustration with child-proofing mechanisms situates us within a world that recognizes that sacrifice for future children is an undeniable good. When Hadley whines about not being able to get a beer, we are to recognize this as both funny and a little pathetic, a man-child learning to balance his own needs against his (future) child's. Sitterson plays the role of the wise elder in their interaction, reminding Hadley that the instinct to protect is "natural" and, by implication, right. Hadley, like all parents, must submit to the technological system of child-proofing, despite its impediments to his own happiness. To think otherwise — to be more concerned with his beer than with his child's safety — is mockingly immature and selfish.
¶ 15 Leave a comment on paragraph 15 0 So the scene is set.
¶ 16 Leave a comment on paragraph 16 0 After showing us the banal white-shirted workplace of Hadley and Sitterson, the film throws us into the saturated, summery world of five college students who banter their way into the movie's ostensible plot: a weekend trip to a cabin in the woods that will eventually go horribly, horribly wrong. As they are introduced, each character is deliberately positioned both as an archetype and as a subversion of type. Curt, for example, barges into Dana and Jules' conversation with a "Think fast!" and a thrown football, but immediately follows up with an educated opinion about Dana's coursework and a suggestion (rife with foreshadowing) about how to manipulate her professor's opinion. Jules, similarly, bops into Dana's room with a brash and sexual sensibility, but all of her denigrating comments about Dana's books are clearly sarcastic, and the first thing we learn about her is that her blonde hair (typically so meaningful) is brand new, an ephemeral fashion choice rather than a permanent identity marker.
¶ 17 Leave a comment on paragraph 17 0 Crucial to the movement of the movie's plot, as it progresses, are the ways that these characters submit to or resist their most simple definitions: scholar, athlete, virgin, whore, and fool. For them to serve their purpose, they must be recognizable as an ideal type, but it must also be clear that something is amiss. The extent to which these characters are stereotypes is not of their own design; their personas, as well as their trip to the cabin, have been engineered by the scientists and managers that work with Hadley and Sitterson in their underground control room. The cabin has been gifted for their use via a mysterious cousin; the chemistry department laced Jules' blonde hair dye with a chemical to alter her state of mind; the control room pumps pheromones into the air and changes its temperature to influence their behavior. At all stages, their path is manipulated to put them in the right place at the right time. Each of them has a specific role to play in the unfolding of Cabin's primary ritual.
¶ 18 Leave a comment on paragraph 18 0 The ritual is, as will become clear, a ritual sacrifice. In the conceit of the film, the human world is built upon — and in the service of — evil gods who live beneath the earth's surface and demand a yearly blood sacrifice of the young. The organization for which Hadley and Sitterson work is the bureaucratic apparatus through which that sacrifice takes place. It works in the fashion of twentieth and twenty-first century institutions of science, segmenting its task into specialized units rife with a multitude of staff, including lab-coated professionals, mid-level managers, technicians, interns, and security staff. (The chemistry department handles mind-altering substances, for example; the demolitions department orchestrates cave-ins and other destruction; Hadley and Sitterson manage the control room; interns scuttle around making bets.) It incorporates a complicated, near unknowable technological infrastructure to complete its task, one which distances technicians both logistically and ethically from their messy work of murder. And with banal predictability, it is run as a workplace hierarchy, with each individual reporting to a manager in turn, from the guard at the door to the Director at the top, who only intervenes in the mess of operations when absolutely necessary.
¶ 19 Leave a comment on paragraph 19 1 The only character who reliably subverts the institutions' intentions is Marty. An exaggerated stoner, Marty is the group's prophet and, ultimately, savior, in his own way speaking, living, and eventually dying Cabin in the Woods' queer truth. When he arrives to join the group at their Rambler RV, he rolls up in a beater car, windows down, smoking out of bong made from a modified stainless steel coffee mug. As his friends reprimand him, he irreverently schools them: "Statistical fact: cops will never pull over a man with a huge bong in his car. Why? They fear this man. They know he sees farther than they, and will bind them with ancient logics." Later, once they are all in the Rambler and on their way, he expounds further:
¶ 20 Leave a comment on paragraph 20 0 "That's the whole point [of the trip]! Get off the grid…One goddamned weekend when they can't global position my ass…Society is binding, right, it's filling in the cracks with concrete. Everything is filed or recorded or blogged. Chips in our kids' heads so they won't get lost? Society needs to crumble, we're all just too chicken-shit to let it."
¶ 21 Leave a comment on paragraph 21 0 He holds up a large joint. "You will come to see things my way."
¶ 22 Leave a comment on paragraph 22 0 This is Marty's queer theory prominently on display. As Halberstam describes her project, "The Queer Art of Failure dismantles the logics of success and failure with which we currently live. Under certain circumstances failing, losing, forgetting, unmaking, undoing, unbecoming, not knowing may in fact offer more creative, more cooperative, more surprising ways of being in the world."[7] As Edelman puts it, "at the heart of my polemical engagement" (and at the heart of Marty's) "lies a simple provocation: that queerness names the side of those not 'fighting for the children,' the side outside the consensus by which all politics confirms the absolute value of reproductive futurism."[8] They see the ways that locking adults, and the children they supposedly serve, into a global technological system actually does little for their own good. You can hear the plaintiveness in Marty's voice as he describes those chips in kids' heads that keep them from being "lost," from experiencing a world in which they might not be rigidly positioned.
¶ 23 Leave a comment on paragraph 23 0 Marty recognizes that this kind of futurist orientation is, as Edelman says, "always purchased at our expense,"[9] as well as at the expense of our future children, who have little hope of making the supposedly right choices, those which would exempt them from sacrifice themselves. Rather, the technological system serves itself. It conservatively serves to perpetuate itself, and with it those who are positioned as its wielders.
¶ 24 Leave a comment on paragraph 24 0 CYBORG EPISTEMOLOGY
¶ 25 Leave a comment on paragraph 25 0 In the original sense of the term, the world according to Cabin in the Woods is a straightforward (if incredibly logistically complex) cybernetic system. Each year five youths are sacrificed, their blood drained into the earth through a series of manually operated pipes, leaving the gods appeased and allowing humanity to begin its preparations for next year's ritual destruction. In this sense, every actor and actant in the film is a cyborg interacting with another human or technological piece of the system. This is especially true of the five youths chosen for slaughter. They are always controlling or being controlled by a mangle of people, chemicals, monsters, and various other technologies of command and control.
¶ 26 Leave a comment on paragraph 26 0 To Donna Haraway, this very mangle provides the opportunity for transcendence — a transcendence not of the material world but rather of one's history and subjective baggage. In her "Cyborg Manifesto," she writes of the "border war" that has been created between the organic and the machine, and sees the creation and employment of this dualism as one of the primary mechanisms through which inequality is made manifest and justified. Instead, she proposes a theory for understanding the world in a "non-naturalist" mode, "a world without gender" which would consequently be a world without birth or origin. For Haraway, the cyborg privileges the knowing, ironic self which imagines itself to be free of its origins because of the thoroughness of its embodied knowledge. Instead of a language of rebirth of the self, which connotes both biological sex and chance for a parental influence, Haraway's cyborgs cope with the world and its violence through a "monstrous" regeneration. Such a world without birth would also, then, be "a world without end."[10]
¶ 27 Leave a comment on paragraph 27 0 Despite the cyborg's emphasis on communication and network building, an individual subjectivity is still central to its ontology. Without even the idol of a potential future child upon which to focus attention, the modus operandi of the cyborg appears to be the further independent development of its own embodied selfhood. But in the cabin in the woods, any faith in an individually embodied self is skewered, proved to be not only folly but itself the very basis for continued oppression.
¶ 28 Leave a comment on paragraph 28 0 The built environment from which Haraway imagines her cyborgs building brand new, asexually reproduced selves is allegorized in the form of the cabin's cellar. The lynchpin upon which the sacrifice hinges, the cellar in the cabin is filled with dozens of evocative objects: a wedding dress and locket, a conch shell, family pictures, film reels, a jewelry box, the diary of a young girl. It is the last, the diary, which finally sets into motion the murderous action of the film. When Dana picks it up and reads out loud the memories of Patience Buckner, it is Dana's choice of this object that calls the whole Buckner family, risen from their zombie graves, to come kill her and her friends.
¶ 29 Leave a comment on paragraph 29 0 The cellar and all of its creepy, gruesome, wondrous possibility is the crucial mechanism through which Cabin's system of sacrifice takes place; it is the illusion upon which the stability of the entire system is predicated. As Dana whispers with horror once she understands, "They made us choose. They made us choose how we die."
¶ 30 Leave a comment on paragraph 30 0 When Truman, a new sentry, is introduced to the control room, it is an opportunity for the movie to explain this system. He is particularly upset by the betting that has developed around the cellar, in which individuals and departments bet on which object (and which connected grisly fate) will be selected by this year's sacrifices. Truman, witnessing the machinations made by the entire crew to even get them to the cabin, questions how such betting can work.
¶ 31 Leave a comment on paragraph 31 0 Truman: How can you wager on this when you control the outcome?
¶ 32 Leave a comment on paragraph 32 0 Hadley: We just get them in the cellar. They take it from there.
¶ 33 Leave a comment on paragraph 33 0 Sitterson: They have to make the choice of their own free will. Otherwise the system doesn't work. It's like the harbinger. He's this creepy old fuck that practically wears a sign: "YOU WILL DIE." Why do we put him there? The system. They have to choose to ignore him. They have to choose what happens in the cellar. Yeah, we rig the game as much as we need to. But in the end, they don't transgress…
¶ 34 Leave a comment on paragraph 34 0 Hadley: They can't be punished.
¶ 35 Leave a comment on paragraph 35 0 The way of the cyborg is not, as Haraway claims, merely non-dichotomous, a "powerful infidel heteroglossia."[11] In actuality, to the extent that it cleaves to cybernetic discourse, it is totalizing in its emphasis on stability. The cyborg creates a new holism out of the wreckage of the built environment. But its goal, ultimately, must be that of the system from which it has so ceremoniously sprung: the continuance of self. (It is no surprise that only Marty, the stoner prophet, is adamant that the group leave the cellar; he is aware of the trap not only of the microcosm of the cabin but also of the trap of human civilization as a whole.) Haraway attempts to find her way out of this dilemma, recognizing that "the main trouble with cyborgs, of course, is that they are the illegitimate offspring of militarism and patriarchal capitalism, not to mention state socialism. But illegitimate offspring are often exceedingly unfaithful to their origins. Their fathers, after all, are inessential."[12]
¶ 36 Leave a comment on paragraph 36 1 Yet her own concern with the future, with the continued subjective experience of the cyborg and the world it inhabits, belies this premise. Cyborg epistemology has incorporated reproductive futurity into its raison d'être. Cyborg fathers are not inessential, nor invisible; they are merely distributed. The cyborg father is Hadley and Sitterson, sitting behind a computer terminal. The father is the voice of the Director through a red phone, chastising underlings. The father is the chemicals pumped into the air to subdue and instigate compliance. The father is the internalized obedience of a young woman who raises a gun to kill her friend, because the alternative — a world without human order — is too much to imagine. The cyborg father proscribes his children's possible modes of engagement, whether he is at their bedside or not, because he has created their conditions of possibility. The cyborg may choose what to pick up, but it's still in the cellar.
¶ 37 Leave a comment on paragraph 37 0 ZOMBIE EPISTEMOLOGY
¶ 38 Leave a comment on paragraph 38 1 Cabin in the Woods concludes with an affirmation of, instead, a zombie epistemology, one grounded in a drive towards death, failure, and a radical, spectacular renunciation of the individual and its symbolic future. Zombies, in their relatively short history as monsters, have been inextricably linked to systems of imperialism, global capitalism, and technoscience. From Haitian legends of zombies raised from the dead to work in sugar mills (White Zombie) to zombies created by rogue radiation brought back from space exploration (Night of the Living Dead) or by a pandemic virus instigated by irresponsible research (28 Days Later), zombies have stood in for the unknown, unacknowledged victims of high-modernist technoscience. Theorists Deleuze and Guattari have called zombies "the only modern myth," referring to our twentieth-century facility with rationalizing death and destruction at the population level, with understanding individual deaths (even many individual deaths) as the price of civilization in a technocratic era.[13]
¶ 39 Leave a comment on paragraph 39 0 In our twenty-first century zombie movie, our human protagonists are the victims of this monolith, although they are no less dead for being living. When Marty and Dana finally make their way down into the bunker where the monsters and the control room are housed, they are met with the disembodied voice of the Director over the loudspeaker:
¶ 40 Leave a comment on paragraph 40 0 "What's happening to you is part of something bigger. Something older than anything known. You've seen horrible things…but they are nothing compared to what came before, what lies below. It's our task to placate the ancient ones, as it is yours to be offered up to them. Forgive us, and let us get it over with."
¶ 41 Leave a comment on paragraph 41 0 In the final minutes of the evening they are met by the Director in person, who confirms the rules of the world in which they are operating.
¶ 42 Leave a comment on paragraph 42 0 The Director: "The sun is coming up in eight minutes. If you live to see it, the world will end.
¶ 43 Leave a comment on paragraph 43 0 Marty: Maybe that's the way it should be, if you've gotta kill all my friends to survive. Maybe it's time for a change.
¶ 44 Leave a comment on paragraph 44 0 The Director: We're not talking about change. We're talking about the agonizing death of every human soul on the planet. Including you. You can die with them, or you can die for them.
¶ 45 Leave a comment on paragraph 45 0 Marty dismisses her offer, but Dana raises her arm to point a gun at him. The Director implores Dana to be strong. Marty watches her. "Yeah, Dana. You feeling strong?"
¶ 46 Leave a comment on paragraph 46 0 But in that moment, two monsters appear that force them stop fighting each other. A werewolf pulls Dana away from Marty, and the zombie Patience Buckner attacks the Director, sending them both into the abyss that leads to the ancient ones.
¶ 47 Leave a comment on paragraph 47 0 The kids are left, beaten and bloody, on the steps of a ritual alter. And so they ask, what if, instead, we fail? What would seem unthinkable to the cyborgs — the destruction of their subjective and symbolic future — now seems the only option left. Dana takes a puff on Marty's last joint and says, "You were right. Humanity… It's time to give someone else a chance."
¶ 48 Leave a comment on paragraph 48 0 Edelman similarly writes, "When I argue, then, that we might do well to attempt what is surely impossible — to withdraw our allegiance, however compulsory, from a reality based on the Ponzi scheme of reproductive futurism — I do not intend to propose some 'good' that will thereby be assured…We might rather, figuratively, cast our vote for 'none of the above.'"[14]
¶ 49 Leave a comment on paragraph 49 0 "None of the above," as I see it, is the abdication of our obligation to the idealized future of our genetic offspring. A proposed zombie epistemology would push this abdication further, freeing us from the intense cultivation of even our cyborg selves. So long as we are building ourselves out of the literal wreckage of war, and knowing our bodies and ourselves using the same instruments of science that have made us experiments (and sacrifices), we will only ever know ourselves as our creators knew us. Though as cyborg we might appropriate knowledge from scientific journals, in applying it we accept as individuals risks that were conceived as applying only to an abstract population. Though we might free the speculum from the hands of a professional gynecologist, in wielding it we internalize the rightness of his vantage point, knowing ourselves as he might see us instead of how we might feel us. Though we might try to make the best possible choices about what to eat, where to live, when to work, and how to take care of ourselves, cyborg choices will always be informed by the science and technologies that were made by powerful people considering the interests of the whole system. The interests of all of the individual cyborgs were never part of the plan, and this makes system-knowledge dangerous to them.
¶ 50 Leave a comment on paragraph 50 1 Zombies cannot deny their place in the horde. They don't have subjectivity. They don't optimize. They don't bricolage. They are the sacrifice to the high modernist system, and thus they can understand the lie: the system does not serve the lives of the majority of its members. The scientists in Cabin in the Woods don't sacrifice five children each year in order to save every other person on the planet (although that is a positive externality); they sacrifice five children each year for the satisfaction of powerful gods. When we punish our bodies to lose weight, optimize our cholesterol, or maximize our fertility, it is because placing ourselves on our physician's bell curve is the only way a cyborg knows how to be good.
¶ 51 Leave a comment on paragraph 51 0 Zombies cannot know themselves, not according to the ways of knowing that generations of scientific establishment have codified. They know themselves to be part of a horde, but their knowledge is local. They are the least powerful victims (it is no accident that, during her life, Patience Buckner was violently abused by her father), but also incredibly powerful as a cooperative. They work, not for the future or for the system, but for themselves.
¶ 52 Leave a comment on paragraph 52 0 To embrace a zombie epistemology is to recognize our limitations as subjects of power, but also to accept the radical implications of not seeing ourselves as high modernism sees us. It is to accept that science treats us as interchangeable members of a population, but to push back against knowing ourselves in the same way. The dictate of the cyborg, internalized from its distributed patriarchy, is to self-actualize, to actively build and rebuild oneself using the tools and knowledge left behind. The dictate of the zombie, in contrast, is simply to be: to be radically embodied, to be present in only the present, to let go of the possibility of discovering, categorizing, organizing, and optimizing a self. As Edelman puts it, "the queerness of which I speak would deliberately sever us from ourselves, from the assurance, that is, of knowing ourselves."[15]
¶ 53 Leave a comment on paragraph 53 0 As Marty might say, isn't it about time? As cyborgs, the teenagers "chose" the means of their own destruction. But as a zombie, Patience Buckner found her way to the Director and ended her own torture. Together, they destroyed civilization.
¶ 54 Leave a comment on paragraph 54 0 What new modes of being might be found in their failure?
¶ 55 Leave a comment on paragraph 55 0 THE ROAD TO THE END OF THE WORLD
¶ 56 Leave a comment on paragraph 56 0 For Joss Whedon, the road to this kind of queerness was a long one. The rejection of patriarchal control over the future has been a constant presence in his work, from Buffy Summers' early rejection of the Watcher's Council to her later insistence on protecting her sister even if it meant ending the world. But as apocalypse threatened, his heroes have always found a way to work out a solution that preserved the world. Even as Angel's team of investigators glibly faced down the destruction of Los Angeles, and presumably the world, at the end of the television series, they still clung to one repeated theme: going down with a fight. (Angel famously stares at the wreckage of the city and directs his team, "Let's go to work.") And as reward for Buffy and Angel's persistence, for buying into, as Edelman puts it, "the insistence of hope itself as affirmation," their world, in fact, does not end.[16] Buffy recognizes that sacrificing herself will save both her sister and the world; a continuing graphic novel series reveals a new future for the City of Angels.
¶ 57 Leave a comment on paragraph 57 1 Cabin in the Woods, instead, embraces an apocalyptic model much closer to the one floated in Dollhouse, in which identity, the soul, and the body were ontologically and technologically split from one another. In this world, a technologically-advanced corporate entity has designed technology to "wipe" the memories and personality from a person's mind and replace them with a newly programmed self. But after a series of events in which selves are misapplied, spontaneously generated, and destroyed, Dollhouse unambiguously showed there to be nothing natural or unalterable about our conception of personhood. Whedon's science fiction is becoming increasingly comfortable with the idea that maybe there is nothing unequivocally good, or necessary, about our individual notion of personhood either. When in their blank state, the programmable "actives" — who are occasionally referred to as zombies in the series — often soothe themselves and others by repeating the phrase, "I try to be my best." At first something of a weak joke (what could it mean for a non-person to be their "best"?), this line achieves poignancy and horror as the audience can grow to see themselves in the actives' place, as dolls who could be made healthy or sick, wealthy or poor, or fulfilled or miserable by changing the conditions of their lives. In that world, who are we, and how do we know it?
¶ 58 Leave a comment on paragraph 58 1 At the conclusion of Cabin, although Marty and Dana regret that they won't be able to see what happens next, they also recognize that there is nothing in the world left for them. Why attempt to preserve a mode of being that they know to be built with the blood of their friends? Their perception of the world, and their agency within it, has already proven to be so malleable as to be a fiction. Why continue to pretend that there is any desirable future in that cyborg vision? What might happen if, instead, as the giant hand of the old one springs from the earth, a zombie rises?
¶ 59 Leave a comment on paragraph 59 0
¶ 60 Leave a comment on paragraph 60 0 [1] Joss Whedon, Cabin in the Woods Blu-ray (Lionsgate, 2012).
¶ 61 Leave a comment on paragraph 61 0 [2] Maria Elena Fernandez, "'The Cabin in the Woods' Spoilers: Drew Goddard Speaks Freely," The Daily Beast, April 16, 2012, http://www.thedailybeast.com/articles/2012/04/16/the-cabin-in-the-woods-spoilers-drew-goddard-speaks-freely.html.
¶ 62 Leave a comment on paragraph 62 0 [3] Joss Whedon & Amy Acker – The Cabin in the Woods Interview with Tribute, 2012, http://www.youtube.com/watch?v=aBBNXazfjnI.
¶ 63 Leave a comment on paragraph 63 0 [4] James C. Scott, Seeing Like a State: How Certain Schemes to Improve the Human Condition Have Failed (Yale University Press, 1998), 4.
¶ 64 Leave a comment on paragraph 64 0 [5] Lee Edelman, No Future: Queer Theory and the Death Drive (Duke University Press, 2004), 7.
¶ 65 Leave a comment on paragraph 65 0 [6] Judith Halberstam, The Queer Art of Failure (Duke University Press Books, 2011), 2.
¶ 66 Leave a comment on paragraph 66 0 [7] Halberstam, 2-3.
¶ 67 Leave a comment on paragraph 67 0 [8] Edelman, 3.
¶ 68 Leave a comment on paragraph 68 0 [9] Edelman, 4.
¶ 69 Leave a comment on paragraph 69 0 [10] Donna J. Haraway, Simians, Cyborgs, and Women: The Reinvention of Nature,(Routledge, 1990), 150.
¶ 70 Leave a comment on paragraph 70 0 [11] Haraway, 182.
¶ 71 Leave a comment on paragraph 71 0 [12] Ibid.
¶ 72 Leave a comment on paragraph 72 0 [13] Gilles Deleuze and Felix Guattari, Anti-Oedipus: Capitalism and Schizophrenia (University of Minnesota Press, 1983), 335. Interestingly, in this instance the history actually belies the film. When Wendy, of the chemistry department, is explaining the system to Truman, he makes the mistake of describing the Buckners as "something from a nightmare." Wendy corrects him; the Buckners are actually "something that nightmares are from," coming from the old world. Unless zombies were merely waiting in the depths of some unconscious nightmare to emerge into folklore and dreams at the appropriate twentieth-century moment, the "zoology" department is responsible for much more than simple curation of the monster archive.
¶ 73 Leave a comment on paragraph 73 0 [14] Edelman, 4.
¶ 74 Leave a comment on paragraph 74 0 [15] Edelman, 5.
¶ 75 Leave a comment on paragraph 75 0 [16] Edelman, 4.

subset: commoncrawl


text:
Luvystypotables (176) Virginia Beach, Virginia | February 14, 2015
Nice ambiance decent selection of beer with great service and food.
Travlr (3078) Charlotte , North Carolina | November 27, 2012
Stopped here for lunch. Strip mall location. Tuna and crab cake sandwiches were very tasty. Good beer selection with a handful of rotating taps and a Virginia cider. Friendly service. Decent enough stop near Williamsburg and walking distance (across railroad tracks) from Williamsburg Ale Werks.
Bells_Boy (1) Williamsburg, Virginia | May 25, 2011
Nice local bar/restaurant. Great food! Nice selection of beers. A few HD flatscreen TV's which usual air current sporting events. Family friendly and a wonderful watering hole to duck into while the spouse/family are shopping at the Prime Outlets. The fish tacos are awesome.


text:
DreamTeam Money Making ForumRegister
Contact Us
Link To Us
Advertise on DTMHelpLog In
Welcome Guest ( Log In | Register )
Members, get paid to surf websites !G.D.Group pays you to view advertisements provided by our sponsors.We strive to connect advertisers with potential customers. This way, both parties benefit from our services. Our innovative features for members give them flexibility and more earning potential. We are always ready to take any advice into consideration.We offer you detailed statistics of your earnings through your own clicks and your referrals. Earn up to Standart Members $0.01 per click and $0.005 for every referral click.http://galaxydollarsgroup.com
Featured Sites:
Sponsor Ads:
Follow Us:
Related Topics


text:
Melanie H.
Chesapeake, VA, 23323
Joined on June, 2014
Gender: Female
Average Rating:
Friday at any time
Saturday after 10AM
Mon/Wed/Fri after 3PM
Saturday after 10AM
Mon/Wed/Fri after 3PM
Lives Near:
Can Meet:
Up to 30 minutes away at my regular hourly rate
EducationAssociates of Applied Science in Biology Broward Community College in Florida, B.S. Investigative Forensics University of MD, B.S. Nursing Tidewater Community College and Norfolk State (currently)
ExperienceExperienced with tutoring Prp school age sudents in all subjects, tutor some high school subjects for a little over 3 years.
Prior Military (Navy) Hospital Corpman, Full time mother of a one year old, full time student and wife of an Active Duty Sailor. I know alot about time management, which i believe is very important in life.
HobbiesAnything involving the great out doors.
Preferred Subjects
High school Biology, H.S. English, H.S. Math, Psychology, Kindergarten - 8th Grade, Algebra
Inquire about this tutor
The tutor will respond if they are available/interested.


text:
A baby warming device is designed to keep the baby warm and provide from basic to a critical care facility in a closed or open environment. There are over 20 million premature babies born every year globally due to low birth weight and other pregnancy-related conditions. The baby warming device needs a constant electric supply and few devices are portable enabling newborns to be kept warm during transport to other emergency care centers. The infant warmer consists of three different parts: a sleeping bag, an electric heater, and a pouch of phase change material. Also, these devices have consistently shown a faster advancement in technology that provides a low-resource setting in remote primary healthcare facilities.
Complete Report Available @ http://www.radiantinsights.com/research/global-baby-warming-devices-market-2016-2020
Covered in this report
The report covers the present scenario and the growth prospects of the global baby warming devices market for 2016-2020. To calculate the market size, the report considers the revenue generated from the sales of baby warming devices through hospitals, pediatric clinics, and labor and delivery centers.
The market is divided into the following segments based on geography:
- Americas
Request A Sample Copy Of This Report at: www.radiantinsights.com/research/global-baby-warming-devices-market-2016-2020/request-sample
Global Baby Warming Devices Market 2016-2020, has been prepared based on an in-depth market analysis with inputs from industry experts. The report covers the market landscape and its growth prospects over the coming years. The report also includes a discussion of the key vendors operating in this market.
Key vendors
- Drägerwerk
- GE Healthcare
- Natus Medical
- Philips Healthcare
- Phoenix Medical Systems
Other reports by Radiant Insights:
- Anesthesia Endotracheal Tubes Market –
- Gastrointestinal Therapeutics Market –
About Radiant Insights
Radiant Insights is a platform for companies looking to meet their market research and business intelligence requirements. We assist and facilitate organizations and individuals procure market research reports, helping them in the decision making process. We have a comprehensive collection of reports, covering over 40 key industries and a host of micro markets. In addition to over extensive database of reports, our experienced research coordinators also offer a host of ancillary services such as, research partnerships/ tie-ups and customized research solutions.
Contact Details:
Michelle Thoras
Corporate Sales Specialist, USA
Radiant Insights, Inc
Phone: 1-415-349-0054
Toll Free: 1-888-202-9519


text:
Action Industries designs, manufactures and distributes a wide range of products for the garage door industry including weatherseals, door hardware, accessories, fasteners, brushes, aluminum retainers, dock kits and cable products. Engineers at Action are highly qualified and experienced in designing products and equipment to complete any project.
North Shore Commercial Door is proud to offer Action Industries products. We have the ability to supply every product that is offered by Action Industries. Below is some of the best sellers that we offer directly on our website. If you are looking for something that is not listed on the page feel free to contact us and we will fill your request.
Shipping costs are based on weight, method, and destination zone.
Purchases may be returned for any reason within 30 days. We do not accept returns after 30 days from delivery.
Start saving money with North Shore Commercial Door coupons!
See what's happening with us! Videos, articles, tutorials, and more!
Privacy PolicySite IndexView Cart


text:
Customised Leadership Training Programmes
We believe that great leadership changes lives.
Inspire Leaders co-creates and delivers solutions that go way beyond traditional leadership training to grow, challenge and nurture great individual and organisational leadership. Because not all great leaders are born; we need to continually learn, practice and grow in all aspects of our lives.
A Way of Being
Leadership is simply a way of being, not a sequence of doing things. It's about the how, rather than the what.
Because of this, we infuse three key themes through all our leadership solutions:
Of course, leadership and business fundamentals are important, but only alongside ongoing development of your mind, body and soul.
We believe in the simplicity of learning, and in maximising impact and value for the learner through applying bold thought leadership.
How we do this is even simpler. It's about context over content, subject matter experience rather than just 'expertise', continual growth and reflection, and a practical grounding in how this can help me today.
This approach isn't just preferable; it's essential. But don't just take our word for it: here's what McKinsey say about why many leadership development interventions just don't hit the spot!
Join the conversation on our Linked In group for our latest leadership insights and opinions.
Being not doing
By shifting focus to the ways and beliefs of leading through reflection, stories, practice and focus on the self, the more memorable, successful and impactful the solutions become. Read more about our approach here.
Inspiring to Lead
We set ourselves a challenge: How could we offer the same benefits of our impactful, tailored and blended programmes to any organisation or leader and at a similar cost to off the shelf programmes?
All of this is now possible. Welcome to Inspiring to Lead. Read more about our programmes here.
Get in Touch
Dan Tohill
Chief Executive Officer+64 27 563 6801 firstname.lastname@example.com more
James McCulloch
Director of Leadership+64 27 248 8848 email@example.com more
Emma Palmer
Project Coordinator+64 4 471 4647 email@example.com more
Gemma Sides
Leadership Design Manager+64 27 420 8078 firstname.lastname@example.com more
Aidan Stoate
Leadership Development Manager+64 (0)27 204 8260 firstname.lastname@example.com
Like what you see?
We are always on the look out for new exciting projects. We would love to have a chat about what you are after over a coffee – our shout.


text:
Your shopping cart is empty!
|1-3 Days
|Rest of India
|4 - 6 days
|North East
|7 - 9 days
(Assam, C'Garh incl J&K)-
Compositon: Each 251 mg tablet contains: Cimicifuga trit.D4, Cocculus trit. D6, Cypri[edium pubescens trit.D6, Ignatia trir. D6, Lilium trit. D6, Passiflora incarnate trit. D3, Platium metallicum trit. D8, Valeriana trit. D2, Zincum valerianicum trit. D4, Lactose and magnesium stearate q.s.
Homeopathic Medicine for Stress relief (Made in Germany)
For the treatment of nervous disorders such as: restlessness, sleep disorders, slightly low mood, mental exhaustion.
Advantages: No risk of addiction, no dizziness, ability to concentrate is not affected, May be taken along with conventional medicines (e.g. psychotropic drugs), Quick dissolving tablets.
Effectiveness: Calming, relaxing, promoting sleep, elevating mood
|Hevert Arzeimittel Gmbh and Co
|Adults and children over 12 years of age: Dissolve 2 tablets in mouth 3 times daily. In acute cases, dissolve 2 tablets in mouth 6 times daily.Children from 6 to 12 years of age: Dissolve 1 tablet in mouth 3 times daily. In acute cases, dissolve 1 tablet in mouth 6 times daily.


text:
Seattle Grace was a chaotic place under new — and in a way, old? — leadership. That was the main takeaway from last night's new episode, "Transplant Wasteland," which saw the fruits of what happened the last time we checked in with our favorite doctor crew in Seattle: Jackson Avery was at the helm of the hospital starting last night.
The whole transition to new leadership, new owners, the Harper-Avery Foundation now backing Seattle Grace, was something like a transition, as — like clockwork — the ever-reliable Meredith Grey told us at the top of the hour."To a critically ill patient, an organ transplant means a new start, a second chance," she intoned with her usual seriousness. "But the body is designed to fight off any invader, even if it's trying to save it. Because a transplant doesn't guarantee that it's an easier life. There's a threat that the body will reject the organ outright."
And that's what seemed to be happening at first, especially when it came to Jackson being in charge of the goings-on at Seattle Grace. Former chief Richard Webber immediately expressed his concern about the Jackson situation to none other than the young man's mother, Catherine Avery (the divine Debbie Allen, who continued her genius run on the soap last night). "What on earth makes you think that young man is ready to take on this kind of responsibility?" he asked Catherine, who responded without hesitation. "He's my son, I know what he's capable of!" And this was the line from Webber that I loved most: "Now he's my boss, and my girlfriend" — referring to Catherine, of course — "is my boss' boss. What could possibly go wrong?" Catherine didn't take well to Webber's suggestions about the situation and delivered a zinger of her own to him. "There's only one room in which I take orders from my boyfriend," she said, referring to the boudoir. "This is not it." Love this lady!
But even though his mother had full faith in him, Avery was hitting resistance in his new position as the hospital's administrator. The first battle he fought was with the cabal of doctors who now own part of the hospital — Shepherd, Meredith, Yang, Arizona, and Callie — over the Harper-Avery Foundation's desire to install new leadership, thus ridding themselves of Owen Hunt. "The thought is that new leadership would be good for morale," he told the doctors, who were simply aghast. Cristina immediately committed herself to putting a stop to the situation: "This thing with Owen is not happening."
NEXT: Owen walks out


text:
- 31 years old
- Date of birth: Mar 29, 1979
- Date of passing: Apr 3, 2010
|Let the memory of Michael be with us forever.
This website was created in the memory of our loved one, Michael. We will remember him forever.
"Even though, I never knew him. I am sure his spirit lives on in the hearts of those who knew and loved him. I lift him and his loved ones up in prayer. May God bless."
"So sorry that you time on this earth had been so very short! I pray that you are watching over your wife and little one that is about to come!
April I know he is with you and your one to come!"
"Taffy, I am missing your strength and compassion. I sure hope you are being treated like a king up there in Heaven. R.I.P. my friend"
"Missing you my friend, but taking comfort in knowing you are free of pain. Rest in peace, Taff.
"Taff, we miss you. We hope you are comfortable and at peace now. We'll do what we can to help take care of your beloved girls.
CurlyGirl & CurlyGirl'sHusband (Kathy & Tim)"
I miss you and I love you with all my heart."
to visit this memorial:
Subscribe to receive e-mail notifications when others contribute to this memorial.
Have a suggestion for us?


text:
TORONTO, January 3, 2017 — Leading global commercial real estate services firm Colliers International Group Inc. (NASDAQ and TSX: CIGI) today announced the completion of the previously announced merger with affiliate Colliers Parrish International Inc. ("CPI").
With this move, Colliers International significantly increases its scale and coverage in Northern California and Nevada with additional offices in San Jose, Oakland, Stockton, Pleasanton, Redwood City, Fairfield, Mountain View, Gilroy and Walnut Creek, California, as well as Las Vegas and Reno, Nevada. The acquisition adds more than 400 professionals providing a comprehensive suite of services including investment sales, lease brokerage, capital markets, valuation and advisory and property management to local, regional, national and international clients.
"We are pleased to have completed this important transaction," said Dylan Taylor, President and COO Colliers International. "Acquiring market leaders in the U.S. and around the world continues to be a core part of our growth strategy as we strengthen our global platform, one step at a time."
About Colliers International
Colliers International Group Inc. (NASDAQ and TSX: CIGI) is an industry leading global real estate services company with more than 16,000 skilled professionals operating in 66 countries. With an enterprising culture and significant employee ownership, Colliers professionals provide a full range of services to real estate occupiers, owners and investors worldwide. Services include strategic advice and execution for property sales, leasing and finance; global corporate solutions; property, facility and project management; workplace solutions; appraisal, valuation and tax consulting; customized research; and thought leadership consulting.
Colliers professionals think differently, share great ideas and offer thoughtful and innovative advice that help clients accelerate their success. Colliers has been ranked among the top 100 outsourcing firms by the International Association of Outsourcing Professionals' Global Outsourcing for 11 consecutive years, more than any other real estate services firm.
For the latest news from Colliers, visit Colliers.com or follow us on Twitter: @Colliers and LinkedIn.
Advisory Regarding Forward-Looking Information
Certain information included in this news release is forward-looking, within the meaning of applicable securities laws. Much of this information can be identified by words such as "believe", "expects", "expected", "will", "intends", "projects", "anticipates", "estimates", "continues" or similar expressions suggesting future outcomes or events. Colliers believes the expectations reflected in such forward-looking statements are reasonable but no assurance can be given that these expectations will prove to be correct and such forward-looking statements should not be unduly relied upon.
Forward-looking statements are based on current information and expectations that involve a number of risks and uncertainties, which could cause actual results or events to differ materially from those anticipated. These risks include, but are not limited to, risks associated with: (i) general economic and business conditions, which will, among other things, impact demand for Colliers' services and the cost of providing services; (ii) the ability of Colliers to implement its business strategy, including Colliers' ability to identify and acquire suitable acquisition candidates on acceptable terms and successfully integrate newly acquired businesses with its existing businesses; (iii) changes in or the failure to comply with government regulations; and (iv) such factors as are identified in the Annual Information Form of Colliers for the year ended December 31, 2015 under the heading "Risk Factors" (which factors are adopted herein and a copy of which can be obtained at www.sedar.com). Forward looking statements contained in this news release are made as of the date hereof and are subject to change. All forward-looking statements in this news release are qualified by these cautionary statements. Except as required by applicable law, Colliers undertakes no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events or otherwise.
Chief Financial Officer
Direct: +1 416 960 9335
President, U.S. Brokerage
Direct: +1 949 724 5513
Executive Vice President
Direct: +1 408 282 3837
Sr. Director, Public Relations & Communications | US Marketing
Direct: +1 206 695 4208
Fill out this short form and we'll connect you right away.
Data for your saved properties is currently unavailable, please check back again later.
{{Summary}} Remove
Select properties to email by checking or unchecking each property to the left.
One or more errors were found with the information you entered into the form. Please correct the information and submit again.
Your message has been sent successfully.
Sorry, there was an error in submitting your email. Please try again later or contact the site administrators if the problem persists
You have no saved properties. Click the 'save' button associated with a property listing to see it displayed here.
The saved properties feature requires cookies to function. Please enable cookies and refresh the page to use this feature.


text:
Download Neuro Sport apk 1.0.05 free for Android smartphone
Posted by Reanimators in Sports | Nov. 1, 2014 | 0 Comments
Apk file size: 103.0 MB
The Neuro Sport application is a powerful self-help and mind management tool that is designed to:
- help focus before an intense workout;
- alleviate anxiety prior to an athletic event;
- aid recovery after an intense athletic effort.
The application generates audio sessions that modulate in special frequencies. These frequencies change and optimize your brainwave patterns so as to improve your athletic performance or speed up your body's recovery. Simply: Neuro Sport tunes up your brain so it is much easier for you to focus before a workout, alleviate anxiety before an athletic event or relax and recover after intensive athletic effort.
Neuro Sport can prove an extremely helpful tool in any situation when you are under stress and feel worried before an important match or a tournament.
Neuro Sport is a great concentration aid and helps you achieve a feeling of physical power and focus before a workout.
Neuro Sport will also help you to recover after intensive athletic effort guiding you to a deep state of relaxation, where your body naturally starts repairing itself and recovering from the athletic activities.
Neuro Sport is powered by Neuroprammer 3 – professional software used by psychologists and psychiatrists.
The Neuro Sport application is safe and there is no risk related to extended use.
To use it you just need a pair of headphones and a mobile phone or tablet.
Reanimators part of our Sports and have average installs from 100 to 500. Last Update Nov. 1, 2014. Google play rating is 60.0. Current verison is 1.0.05. Actual size 103.0 MB.


text:
Viacom Websites Crash
The websites of a number of properties owned by Viacom Inc.–including the homepages of Comedy Central's "The Daily Show" and "The Colbert Report"–have been taken offline. In addition, stories on Viacom's MTV.com website were experiencing problems.
Viacom said it is trying to fix the technical difficulties.
Visitors to "The Daily Show" website are greeted with the message "Sorry, www.thedailyshow.com is currently undergoing maintenance. Please check back shortly!"
Visitors to "The Colbert Report" website are greeted with a similar message.
Both sites had been experiencing bugs in recent days. "The Daily Show" website wasn't displaying all the latest clips from the show. And "The Colbert Report" website wasn't allowing users to embed or play some videos from the site.
The main website for Comedy Central, which airs both shows, has been taken down as well.
More after the jump.


text:
Introduction. Statutory Recycling and Diversion TargetsThe new industryTHE LegislationSustainable exports?Sustainability?. What\'s in your dustbin?. UK Waste Generation. EU Landfill Directive. Statutory RecyclingTargets. UK 23%. LONDON 15%. Government estimate 200 MRF\'s required. Actual Recycling Targets.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


text:
Alton Towers crash victim speaks for first time since rollercoaster horror smash
A VICTIM of the Alton Towers rollercoaster crash has been left "overwhelmed" with the response since the incident.
Joe Pugh, 18, and his girlfriend Leah Washington were on the £18million Smiler ride when it smashed into another carriage, injuring both of them.
Joe tweeted: "So overwhelmed with the response I've had from my accident at Alton towers, Thankyou for everyone's concern."
Joe and Leah were on the front row of the ride on Tuesday afternoon.
Another couple aged 19 and 27 also suffered serious leg injuries following the crash at the Staffordshire theme park.
Two hours before the horrific smash Joe tweeted: "Been at Alton towers two mins and some t*** already ran my foot over with a pushchair."
Joe, a Huddersfield University student, works part-time at Oaks Working Men's Club in his hometown of Barnsley.
His boss Steve Hibbert said: "All I know is that Joe has two broken legs and his girlfriend was airlifted for emergency surgery.
"So overwhelmed with the response I've had from my accident at Alton towers, Thankyou for everyone's concern"Joe Pugh
"We hope Joe's OK. He seems like a really nice kid."
"It was their first official date," a barmaid at the club added.
Vanisha Singh, who was also riding on the Smiler at the time of the crash, said people on the rollercoaster joked they were "guinea pigs" during the incident.
Speaking to The Sun she said: "We finally went up and were kept at the top for ten or 15 minutes chatting, joking that we were the guinea pigs.
"Then we plummeted down and smashed into the test car after doing a couple of loops.
"There was blood all over the floor because it was pouring out of their legs in the carriage and dropping down."
Alton Towers remained shut on Thursday and bosses have said it will be closed "indefinitely" while an investigation is carried out.
A top personal injury lawyer has warned compensation claims could top £1m.
Nick Turner said: "Compensation payouts for life-changing injuries should start from £250,000."
An Alton Towers spokesperson said: "We are currently making contact with the families of all those involved and will continue to communicate with them.
"The Health And Safety Executive remain on site and Alton Towers is co-operating fully with the investigation.
"This has been a terrible incident."


text:
FAQ: What is a Novated Lease, and how do they work?
A Novated Lease is a vehicle lease agreement between you, your employer and a finance company. Novated Leasing is also known as car salary packaging or salary sacrifice.
Entering into a Novated Lease means that your employer agrees to pay your vehicle lease payments out of your pre-tax salary. Paying with pre-tax dollars can effectively save you money as your income tax is calculated on the reduced total of your salary or wages minus car payments. Your disposable income is greater than it would be if you were paying for the same vehicle with post-tax dollars.
If Novated Leasing is a benefit offered by your employer, you're able to choose the vehicle you wish to drive without the restrictions that typically apply to a company fleet. Once you've purchased the vehicle and made the finance arrangements in your own name, you then enter into a Novation Agreement with your employer.
You agree to "salary sacrifice" part of your earnings in return for the benefit of the car and related costs. Your employer agrees to be responsible for making your lease payments and other agreed costs for the term of your employment.


text:
The lifetime value of a customer is an often overlooked metric in most businesses, especially in the online marketing world. This is a mistake, because I believe it's the most important metric in any business. It's the metric that will help you make the right decisions and create more profit while working less…
My background was mostly with brick and mortar businesses before I came online. But, I based many of my niche selection and online business decisions on achieving a higher lifetime value of a customer.
It made no sense to me, to chose a niche I was passionate about, but could only ever achieve a lifetime customer value of less than $30. That would mean having to sell to tens of thousands of people to create a reasonable income. It's probably the quickest way to destroy my passion with the frustration of trying to make money from the niche, when there was really not much money to be had in the first place.
The alternative is to go into a niche I was less passionate about and could achieve a lifetime customer value of over $2,000.00. It required selling to less people, which mean't less work for more profit…
Let me explain lifetime customer value with an example…
Kim mows our lawns. He charges $40 for each mow and usually mows every fortnight. Kim has been mowing our lawns for over 5 years.
What is Kim's average customer lifetime value…
$40/mow x 25 mows/year x 7 years (average stay in one house) = $7,000
If Kim's average lifetime value of a customer is $7,000, he could spend a few thousand dollars to get one customer, and still be profitable.
It also makes his business more valuable and sellable, because the future income is almost guaranteed…
When I initially sold my model train ebook (on it's own), my average customer lifetime value was $27. I added the membership component and it went from $27 to over $110.00 almost overnight.
My offer on Clickbank became popular with affiliates, because instead of spending $0.15/click to make a $27 sale, they could spend up to $1.17/click to gain better quality traffic and make an average sale of $117 or more.
They could pay more for traffic and beat the competition!
Mowing lawns or selling an ebook, the secret to doubling or quadrupling profits quickly, is to focus on and improve your average lifetime customer value.
You probably already know that it is about 7 times easier to sell to an existing customer (because they like and trust you) than it is to sell to a complete stranger to your business.
So, doesn't it make sense to try and maximise the average customer value?
Memberships and Subscriptions are where the BIG profits are in your business. They provide a consistent and reliable income, as well as make your business more valuable and sellable.
Now I can hear you asking. How could I create an ongoing subscription program from my product?
Let's take Dan's product (The Ultimate Track day Guide) as an example…
Dan sells this ebook for $19. Dan's sales funnel is basically traffic to optin to autoresponder messages to sales page to order page.
Each one of those "touch points" can be measured and improved. The traffic source can be improved, the optin funnel can be improved, the autroresponder emails can be improved and the sales page conversion can be improved.
All of these "touch point" improvements WILL result in an improvement to the bottom line (net profit). But the truth is that there is no end to these improvements. Dan may get to the point where he believes the conversions are acceptable. But, until he gets 100% conversion at every level, he should NEVER stop testing and tweaking.
Note: 100% conversions at each level is almost impossible, but don't be mislead by what other so called experts tell you. If you have targeted traffic and have identified your avatar (more on this later) then there is no reason to accept anything lower than a 50% optin rate and a 30% sales page conversion rate.
Think about when you opted into a squeeze page… More than likely it's because the message spoke directly to you. It pre-qualified you and it offered a bribe that you thought was worth giving away your email for.
Now, if ALL the traffic going to that squeeze page was just like you, they could expect a 70% conversion rate, or more!
The same applies to something you have bought online. Think about the previous research you did online before buying? Why did you buy from that website? Was it the design that made you feel like you trusted the website? Was it the message that spoke directly to you and your situation? Was it the credibility, the rapport with the seller, or something else?
Carefully think about your answers and make sure your website ticks all the boxes. That's how you get awesome conversion rates…
But, the biggest profits will come from Dan increasing his lifetime customer value. Instead of each customer paying $19, Dan needs to get them paying $19/month (or more) and staying subscribed for up to 24 months.
How does Dan do that?
From Dan's sales copy, I can see that Dan's ebook consists of at least 10 segments. Here's how Dan sells them…
Every one of those segments probably has about 10 pages dedicated to it. Now, if the beginner rider had to hire a coach do you think they would cover everything in one sitting. No, of course they wouldn't!
They would focus on one aspect, refine it and when the rider had got to a satisfactory level, move onto the next aspect of track day riding. Each aspect could take 3 or 4 lessons with a whole lot of practice in between.
A serious rider may be coached for many months or years. And, not only will they be coached, they will be doing their own research to further improve their skills.
When people are passionate and committed, they want all the information they can get their hands on. They want people they can ask questions. They want to talk to like-minded people of various skill levels. They want to see the best YouTube videos available on the subject, read the best articles on the subject, listen to the best podcasts on the subject, etc.
Dan can provide a solution to all their requirements with a membership site. The easiest and quickest way to start Dan's membership site is to take all the chapter headings of his ebook and just flesh them out.
I won't go into great detail because I have covered setting up membership sites and creating content for membership sites in great detail on other posts.
But, what I will do is cover the creation of your avatar. Because, if you are crystal clear on who you are selling to and know EXACTLY what their needs are, you can fulfill every one of them…
An avatar in the internet marketing world is an imaginary A-grade customer that you create. They are the exact customer you want and all your sales messages will talk directly to them.
For example… my avatar for my model train product was John.
John was 65yrs old, lived in Seattle and had 3 grandchildren.
John was retired and had lots of time and disposable income.
John thought it would be a great idea to build a model railroad with his grandkids. They could do it together in his shed and it would be something they could build and operate for many years to come.
John liked the idea that it would get the grandkids off the playstation and teach them some planning, building, electrical and modelling skills.
John had never built a model railroad before, but was fairly handy and willing to give it a go. He was a bit confused with the different scales and DCC, so he just needed some basic how to information to get started…
…And that's where my product "Model Trains For Beginners" fills the need.
Having an avatar makes it soooo much easier to create great converting marketing messages!
Every time I created an optin page, a sales page, an email or any marketing message, I always created it for John.
I made sure that every time I spoke, I was speaking directly to John's needs. I never wrote as if I was addressing a group of people. I always wrote as if I was personally talking to John who was a friend, that I wanted to help.
Try it! Create an avatar for your business, and then go over all your marketing messages. Are the messages talking directly to your avatar?
Got a question, want to make a comment or provide some feedback? You can do that in the comments area below or by contacting me here…
The complete A-Z map to turn your knowledge, talents, and abilities into an information product that can be sold online to people all over the world. Start building your online business today...Send My Book
The Income You Earn Is Based On The Level Of Value You Provide
Here's How To Guarantee The Success Of Your Internet Marketing Business
One Reason Why You May Not Be As Successful As You Should Be
How To Improve The Conversion Elements Of A Blog


text:
The Radiology Department at Zuckerberg San Francisco General is located on the first floor of the main building. Radiology can be found by entering the main entrance of building 5 and walking straight down the hall (we are at the end of the hallway). The general radiology department is a very busy area of the hospital providing x-ray services to all campus facilities and outlying clinics.
Zuckerberg San Francisco General is a Level One Trauma Center, therefore the Radiology Department is open 24 hours a day, 7 days a week. We are also required to have minimum staffing levels to meet the trauma needs of San Francisco. There are 4 general x-ray rooms and 4 trauma rooms (one dedicated specifically for pediatrics) and each room has 360 tube capability, which enables us to shoot x-rays quickly and effectively. Our technologists are at the top of their game and are considered some of the best nationally.
Team work is emphasized in radiology from the clerks, to the lab aides, to the techs and the UCSF doctors who all strive to give the utmost of care to every patient. Being a level one trauma center, there can be delays and trauma will take priority over stable patients, however we do our best to accommodate everyone appropriately.
Medical Clinics & Services
© Copyright 2016, Department of Public Health, City and County of San Francisco.
Any questions, comments or suggestions about this site may be directed to Linda Acosta.


text:
- Home
- Nissan
- Nissan RB20 & RB25 & RB26
- Engine Components
- TOMEI GENESIS RB28G Complete Engine Assembly - Discontinued
Tomei started in 1968 as a race car tuner in Japan, which has emerged as one of the world leaders in research, racing, and automotive culture. Today, Tomei products have been utilized in nearly every motor sport imaginable. Tomei's racing heritage means its research and design team have first-hand knowledge of the extreme demands racing puts on an engine, and this Tomei engine provides the reliability and performance that discerning pros and hobbyists demand.
Quality You Can Depend On
Because Tomei uses only the highest quality materials, you can rest assured that this Tomei engine can handle the intense strain and heat a purpose-built engine is bound to experience, whether on the street or the track. All of Tomei's products are thoroughly researched and engineered to achieve optimal efficiency, and the company's attention to detail is second to none.
Because even minuscule differences in measurements can cause engine failure, all Tomei products fall within strict tolerances. Tomei machines all of their engine components to enhance airflow and ensure proper fitment and seal.
Get More Value at Enjuku Racing
For the best price on a genuine Tomei engine, look no further. Here at Enjuku Racing, we're committed to quality, and we stand behind each and every product that we sell. As proud members of the automotive community, we always go the extra mile to keep our customers satisfied, and that's why we offer the best guarantees and customer support in the industry. Call 1-888-SR20DET for more information, or simply place your order online today.
Customers also viewed


text:
COLUMBIA, Pa. (WHTM) – Commonwealth Court has ruled that Club Good Times in Columbia, Lancaster County can no longer allow its dancers to be all nude.
Last year, a county judge allowed all nude dancing because Columbia zoning didn't forbid it.
The borough has since changed its zoning because a field used by the Columbia School District is nearby.
So, no more nude dancing. The women will have to be partially clothed.
Get breaking news, weather and traffic on the go. Download the ABC27 News App and the ABC27 Weather App for your phone and tablet.


text:
Hi Ladies!
Sew What is gearing up for the upcoming events!
FAT QUARTER TUESDAY is February 28 this year. The store will be open from 9am-7pm. All the fat quarters will be only $1.75. Please note that this special Fat Quarter Tuesday price has not increased in ten years! It's quite a deal, and you should definitely take advantage of it. We have been cutting and folding, cutting and folding, cutting and folding for a month now, and we have literally thousands of Fat Quarters to offer you.
We will have a fully stocked clearance section, and the remnant section has been filled up. Come see what you cannot live without and get a great bargain price.
Also, we are very excited about our Spring Seminar Spectacular 2017. The dates for this fun event is April 26-29, 2017. It's in a new location this year, the Best Western Hotel on Transit Road in Lockport. It will be much closer for those of you in the Southtowns. We have an awesome lineup of classes this year, and we are very excited about our wonderful teachers. The classes will be $58.00 if you take one class, but you will get a little break on price if you take more than one class. Two or more classes will be $54.00 each. Lunch will be included in this price. The Best Western does have a special room rate, only $79.00 per night if you sign up by March 26. Why not grab a couple of girlfriends and make a retreat weekend out of it? Sounds like fun to me!
Here's a sneak peak at some of the classes from the seminar class list.
Here's the full seminar class list:
Questions? or to sign up for classes, call Sew What at 716-632-8801
This entry was posted on at and is filed under Quilting News Letter. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.


text:
30 Free Paint Brush Fonts for Artistic Designs
Are you looking for a trendy, elegant, and casual fonts you can use free for your design projects? Paint brush fonts will give your designs a vintage and DIY feel. Thus, they are perfect for flyers, posters, greeting cards, and other crafty projects. If you are not convinced yet, then try these 30 free paint brush fonts that we have assembled in this roundup.
35 Cool Text Effects Using Smart Layers in Photoshop
Creating cool text effects in Photoshop has now become so much easier and fun. Thanks to the Smart PSD, we can now download pre-made text effects that we can customize to suit our own requirements. In the earlier days of designing in Photoshop, we usually make text effects using either the Photoshop Style or Photoshop actions. These techniques are a lot more complicated and customizing them is not also easy.
15 Free Cool Lettering Font Types for Fun Designs
To help you come up with creative and fun designs, we are featuring today 15 new and cool lettering fonts. Handmade lettering fonts are becoming more and more popular. You see them in almost any medium–print, web and multimedia. Combine these fonts with hand drawn design elements like flowers leaves and nature design elements and a nice watercolor background to create cool and original designs.
12 Free Fresh Fonts for Spring 2016
One of the main considerations when creating graphic designs and artworks is the choice of fonts. Spring is a fun and lovely season so our designs must also look fun and lovely. To help you achieve that, we decided to share with you our top choices of beautiful fonts that you can use in your Spring designs for free. Yes, we will list down only free fonts with links on where you can download them.
22 Free Halloween Fonts for Making Scary Designs
Before you know it, the Halloween and Fall holidays will be here. So we are sure some of you are now starting to work on projects for this special time of the year. In this post, we put together some of the most gruesome. and creepiest free fonts out there that you can use for your Halloween-themed designs. These fonts are perfect for labels, invitations, posters and flyers to ghoulish parties, and menus for frightening dinners and feasts!
25 Free Outlined Font Types to Download
Forget about video games and tech gadgets. Coloring has been a growing trend among adults. Outlined font or those hollow typefaces are a fun way to color texts. Download these 25 free outlined font to create coloring books or other designs. Download them now and start coloring these fonts.
31 Sets of Free Symbol and Icon Fonts for Web and Logo Designs
Dingbats or symbol fonts are among the best source for free icons that you can use for your website and signages as well as for designing logos. So today, we put together a long list of free symbol and icon fonts that you can download and keep for future use. We are sure you will find these icon fonts handy in your future projects.
18 Free Monogram Font Types for Logo Designs
Monograms are created by combining or overlapping two or more letters to form one symbol. Usually, monograms are formed by combining the initials of a person or a married couple or a company, to be used for identity and branding materials or as recognizable symbols or logos. Here are 18 free monogram font and types that are great for making trendy logos, wedding invitations, business cards, stationery, etc.
25 Free Movie Font Types for Making Film Posters
Find free fonts based on the type used in popular box office hit movies and use them to create your own posters of your favorite films. In this list, you will find 25 free-to-download movie font types that you can use for making your own posters of your favorite films.
17 of the Best Free Embossed Fonts to Download Now
Make your text look as if it has been lifted off the page by using embossed fonts. These type of fonts are great for large titles and headings and should not be used for body text since they are difficult to read in smaller sizes. Also, embossed text is nearly invisible with some color schemes. So make sure you have good contrast by choosing the right background color or texture.


text:
At the Cyber Defense Summit in 2016, FireEye introduced Helix, an intelligence-led platform to simplify, integrate and automate security operations for organizations of all sizes and in any industry. Driven by FireEye iSIGHT intelligence and Mandiant expertise, the platform provides network to endpoint protection and integrates security tools across your infrastructure.
FireEye Helix will enable customers to reduce the time, effort, and cost associated with security operations by addressing three critical needs:
- Accurate Detection and Alerts: Identify known and unknown threats while minimizing low quality and false positive alerts and improving response times. To accomplish this, FireEye Helix integrates:
- Codified FireEye iSIGHT intelligence and Mandiant expertise
- Network and endpoint detection capabilities that use the patented FireEye MVX technology
- Third-party alerts from your existing security solutions
Intuitive User Interface: Built by security analysts for security analysts, FireEye Helix is designed to accurately correlate and prioritize threats for appropriate response. Customizable dashboards, search and reporting capabilities facilitate investigations and accommodate compliance regulations.
Accelerated Response: Built-in playbooks help automate and streamline workflows to respond to and remediate incidents in real time. These playbooks are developed using over a decade of Mandiant experience responding to the world's most sophisticated threats and FireEye intelligence on the attacker tools, techniques and procedures (TTPs).
Slash your incident detection-to-response time from days to minutes while optimizing resources. Join us to learn how FireEye Helix can work for you and get details for early access.
Free Report
All webinar attendees will receive a free copy of our latest special report, FireEye: Transforming Security Operations.
Attending RSA Feb 13-17?


text:
Slovakia: City and Town Maps. Old Antique Map Prints and Pictures
Historical plans and old maps of cities and towns in Slovakia record the evolution of their urban development, infrastructure, transportation like railways, metros and tramways, change of street and district names of each metropolis or township in detail. Old antique maps and plans like these have been the principal sources for touring and getting driving directions across places in Slovakia in these times. The site offers fine old historical map reproduction prints for a gift or home design, high resolution pictures for download and and navigable GPS-enabled historical travel items for PDF Maps mobile application
3.35 x 3.24 inch, 86 x 83 mm
3.51 x 3.44 inch, 90 x 88 mm
2.29 x 1.93 inch, 59 x 49 mm
6.67 x 4.04 inch, 170 x 103 mm


text:
p.2 Marine Notes
Port Colborne, Aug. 7th - Up - schrs. Falmouth, Sodus, Toledo, light; Albacore, Port Dalhousie, Toledo, light; Denmark, Kingston, Toledo, light; F. Emma, Oswego, Leamington, light; D. Lyons, Fair Haven, Chicago, coal.
p.3 Collision - This morning while the schooners Ellsworth and E.R. Williams were coming down the channel between Snake Island and Four Mile Point, they collided. The Ellsworth lost her main mizen boom, had her mizen torn, besides breaking her mizen boom and the lanyards in her rigging. The Williams had her mizen rigging damaged and her square sail badly torn. The captain of each vessel blames the other, and it is a matter of difficulty to know which is in fault. The matter will be referred to arbitration.
Yachting - The yacht Zephyr, from Belleville, with S.T. Greene, S. Brown, S.S. Wallbridge and W. German, arrived here this afternoon on her way to Alexandria Bay, for a two weeks' cruise.
The Maritime History of the Great Lakes site is managed by Walter Lewis
Since 2005 this site has been the prototype for the digital collection management tools built for the Our Digital World (formerly the OurOntario project of Knowledge Ontario.)
As a prototype it is subject to occasional, unexplained interruptions in service ... because we keep trying new things.
My favourites lets you save items you like, tag them and group them into collections for your own personal use. Viewing "My favourites" will open in a new tab.
Login here or start a My favourites account.


text:
- Home
- Information
- Research
- Images
- Forums
- Patients
- Contact
Diagnosing Degos
Degos disease (malignant atrophic papulosis) is a rare progressive, small and medium size arterial occluding disease, leading to tissue infarction initially involving the skin and later the gastrointestinal, ocular and central nervous systems.
The disease is characterized by papules that develop porcelain-white centres and telangiectatic borders. This is the clue to the underlying disease which can affect the gastrointestinal tract and central nervous system and may lead to death.
The skin biopsy places the pathologist at the centre of the diagnostic evaluation. (See biopsy plates below and under Images
In 1941, in an article entitled "Multiple Hautrekrosen bei Thromboangiitis obliterans," Kohlmeier described a case of a disease that has now been termed malignant atrophic papulosis (MAP) or Degos disease (DD). Degos recognized it as a distinct clinical entity in 1942.
Broadly speaking, DD is a vasculopathy or an endovasculitis. It is an occlusive arteriopathy involving small-calibre vessels. Specifically, it is a progressive, small- and medium-size arterial occluding disease, leading to tissue infarction and initially involving the skin. DD occurs both in a limited benign, cutaneous form and in a lethal multiorgan, systemic variant.
In the skin, DD initially manifests with erythematous, pink or red papules. These papules heal to leave scars with pathognomonic, central, porcelain white atrophic centers. These papules usually have a peripheral telangiectatic rim.
In the systemic variant of DD, the gastrointestinal tract is affected in 50% of cases. Intestinal perforation is the most severe complication and the most common cause of death in systemic DD. Other systems can also be involved; approximately 20% of cases of systemic DD involve the CNS. Systemic manifestations usually develop from weeks to years after the onset of skin lesions, or, in rare instances, they may precede the skin lesions.
Synonyms and related keywords
DD, malignant atrophic papulosis, papulosis atrophicans maligna, Kohlmeier-Degos-Delort-Tricot syndrome, Kohlmeier-Degos syndrome, Köhlmeier-Degos' disease, Online Mendelian Inheritance in Man 602248, OMIM 602248, papuleuse maligne atrophiante, lethal cutaneous and gastrointestinal arteriolar thrombosis, fatal cutaneointestinal syndrome, thromboangiitis cutaneointestinalis disseminata, dermatite papulosquameuse atrophiante, MAP
The etiology and the pathophysiology of DD are unknown. Some have classified DD as a vasculitis, a mucinosis, or a thrombotic disorder. In most cases, no circulating immune complexes, antiendothelial cell antibodies, or anticardiolipin antibodies are isolated. Although, in some cases, antiphospholipid antibodies of uncertain significance are identified.
Some authorities suggest that DD involves a primary endothelial cell defect with secondary thrombosis, leading to infarctive changes. No evidence exists for antibodies to components of endothelial cells. Medications and toxic chemicals do not appear to induce DD.
The actual physical damage to blood vessels involves, at least in part, impaired fibrinolytic activity and alterations in platelet function. Classifying DD as a vasculitis may not be appropriate because inflammation of the vessel walls is minimal and because immune complexes have not been found in the vessel walls.
Three possible mechanisms for this pathology have been suggested: disturbance in immunity, viral infection, and abnormality in the clotting system of blood.
In familial cases, an autosomal dominant mode of inheritance has been suggested, but this is uncertain.
In molecular analysis of cases of DD with only cutaneous lesions , no paramyxovirus was identified by polymerase chain reaction (PCR).
Lab Studies
- No specific laboratory test can be used to aid in diagnosing DD. In fact, most laboratory test results are normal, with the exception of the manifestation of anemia secondary to intestinal bleeding.
- In 1 patient, laboratory examinations disclosed persistent elevations of the thrombin-antithrombin III (TAT) complex, plasmin-alpha 2 plasmin inhibitor complex (PIC), and cytotoxic T-cell subset (CD8 + CD11 – ), illustrating the coagulative, fibrinolytic, and immunologic implications of DD.
- In a series of 3 patients with DD, prolonged euglobulin lysis time, increased plasminogen activator (PA) levels, and increased plasminogen activator inhibitor (PAI) activities were detected before and after a venous occlusion test, indicating an inhibition of fibrinolysis.
- In a series of 3 patients with DD, electron microscopy demonstrated an increased number of Weibel-Palade bodies and a raised staining of von Willebrand factor in endothelial cells in 1 patient.
- In a series of 3 patients, test results for coagulation and circulating anticoagulant were in the reference range.
- In a series of 3 patients, the results of platelet adhesion showed decreased adhesion in 1 patient and increased adhesion in another patient. Platelet aggregation study results were in the reference range in 2 patients, and the results showed hyperactive spontaneous and induced aggregation in 1 patient.
- Amounts of protein in the cerebrospinal fluid (CSF) and amounts of platelet aggregation have been reported as sharply increased in progressive stages of the disease. For example, laboratory results showed a gradual increase of CSF proteins (from 156 mg/dL to 602 mg/dL) and an extremely increased amount of platelet aggregation.
- In DD, viruslike inclusions are frequently present in the endothelial cells and fibroblasts. C3 deposits and the presence of intracytoplasmic cylinders are also frequently present in the histiocytes.
Imaging Studies
- MRI of the brain can show multiple cerebral infarctions accompanied by small hemorrhagic areas and gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) enhancement of the dura. They can also reveal intracerebral bleeding, subdural hemorrhage, and cord infarcts.
- A cerebral angiogram may reveal narrowing and occlusion of small intracranial arteries. Specifically, a cerebral angiogram can depict stenosis, ectasia, and aneurysms involving the peripheral branch of arteries.
EEG tests have shown generalized nonspecific slowing.
- In some patients, electromyograms (EMGs) demonstrate axonal and demyelinating polyneuropathy.
- With angiograms, stenoses can be observed in the celiac artery and the small arteries in the kidney.
- In some patients, chest radiographs have depicted extensive calcification of the pericardium. Although pleural involvement and pericardial involvement have been reported in DD, constrictive pericarditis is most unusual, and radiographically demonstrable calcification of the pericardium has not been previously reported.
Other Tests
- Endoscopy of the gastrointestinal tract (ie, stomach, esophagus, duodenum, colon, rectum) can show infarcted lesions or ulcers.
- Laparoscopy of the intestine can show similar type lesions that manifest with white plaques with red borders on the serosal surface of the bowel and the peritoneum.
Histologic Findings
Early papules in DD are skin colored and can demonstrate a superficial and deep perivascular, periadnexal, and perineural chronic inflammatory cell infiltrate associated with interstitial mucin deposition. The overlying epidermis can show a mild vacuolar interface reaction, and, at this early stage, the histologic appearances can resemble tumid lupus erythematosus.
Fully developed papules can be raised with umbilicated porcelain white centers and a surrounding erythematous rim. Usually, wedge-shaped degeneration of collagen is present. A prominent interface reaction with squamatization of the dermoepidermal junction, melanin incontinence, epidermal atrophy, and a developing zone of papillary dermal sclerosis that resembles the early stages of lichen sclerosus et atrophicus in miniature can also be observed at histologic examination. These interface reactions are usually confined to the central portion of a punch biopsy specimen, corresponding to the central, porcelain white area seen clinically.
Histopathologic examination of the skin biopsy specimen can also show hyperkeratosis, epidermal atrophy, dermoepidermal separation, edema, and necrosis in the papillary dermis. Fibrinoid necrosis and thrombosis can be seen in the papillary dermis and in the vessels below the lesions. Others have noted that skin biopsy specimens show hyperkeratosis, atrophy of the epidermis, and necrobiosis of the collagen layer. Well-developed lesions with epidermal atrophy and hyperkeratosis overlying a wedge-shaped area of cutaneous ischemia extending into the deep dermis have also been observed. Superficial and deep perivascular lymphocytic infiltrate can be present at the edge of ischemic areas. Marked endothelial swelling and occasional platelet-fibrin thrombi can be present. The epidermis may show infarctive changes or scattered necrotic keratinocytes. Abundant acid mucopolysaccharides can be present in the dermis giving the appearance of a dermal mucinosis.
Direct immunofluorescence (DIF) yields conflicting findings with perivascular fibrin and complement in variable instances. An autopsy examination confirmed the clinical diagnosis of the syndrome by the finding of thromboangiitis of the Burger type, with bland infarcts of the small intestine and perforation of the jejunum. Microaneurysms of the bulbar conjunctival vessels have been described. Changes in the kidney manifest with thickening of the afferent glomerular arterioles and the capillary basement membrane.
Biopsy Plates
Drupal theme by Kiwi Themes.


text:
Pertussis, more commonly known as whooping cough, is a very serious disease, especially for infants.
It's often spread to babies from older kids or adults who may not even know they have it.
Whooping cough is a real threat to your baby today.
To stay protected, get your baby and everyone around your baby vaccinated. Vaccination is protection. Learn more at http://www.cdc.gov/pertussis. B96 Cares!