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Accounting Assistant
Requisition ID 2064
Position Type FT Fixed Term
Posting Type DNI
Leading to better encompasses all we do at Kerry, it's how we've become the worlds leading taste and nutrition company. Whether it's building and manufacturing sustainable solutions for food, beverage or pharmaceutical consumers, our commitment to lead the world to better nutrition drives us forward. With 25,000+ colleagues across the globe and 15,000+ Kerry products, your opportunities are limitless.
About Kerry
A career with Kerry Taste & Nutrition offers you an opportunity to shape how people across the globe view food and beverage while providing you opportunities to explore and grow as your interests do. With our commitment to a sustainable future, a career with Kerry is something you can feel good about.
Key responsibilites
- Manage accounting transactions A/P and GL.
- Weekly and monthly sales and gross margin files reports.
- Support on preparation of month-end accruals.
- Support month-end and year-end close process
- Ensure quality control over financial transactions and financial reporting.
- Support to finance manager to develop and document business processes and accounting policies to maintain and strengthen internal controls.
- Support in different projects.
Qualifications and skills
- +5 years of experience in accounting functions.
- University degree. Studies related to Finance, Economics or Business Administration.
- Strong accounting know-how and accounting skills.
- English Advanced Level
- Excellent Excel skills.
- Experience from SAP. Mandatory.
- Experience from Navision. Nice to have.
- Team player offering support to others.
- Takes responsibility for personal improvement, learning from experience and new situations.
- Ability to work under pressure, teamwork, detail and service orientation and accounting helpful.


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Product Details
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Product Reviews
Hand wrapped in biodegradable plastic
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subset: commoncrawl


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Fire engulfs Chon Buri textile factory
Breaking News March 06, 2019 16:45
By The Nation
A fire hit two warehouses at a textile factory in Chon Buri's Ban Bueng district on Wednesday morning.
The fire at the Dtex Industry Co Ltd's factory in Moo 1 village in Tambon Map Phai started before 6:30am.
Ten fire engines arrived when the fire had swept through the first warehouse, whose roof collapsed, and the fire had spread to the second building.
Firefighters managed to control the blaze in the second building.
Police learned from workers that the factory operated its textile machines permanently with 10 workers manning equipment on each shift.
Police have yet to conduct an investigation.


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Mom & Tom - A Mother's Day Brunch
Are you searching for something special to do for Mom? Why not treat her to the best Mother's Day ever and join us at Palace Ballroom for a delicious spring brunch complete with cooking demos by the one and only Chef Tom Douglas!
The pampering begins with mimosas, then Mom and her entourage will enjoy pastries, fruit, and a three-course brunch menu. As Tom demos each course of the menu, he will give valuable tips on cooking techniques while sharing personal stories and amusing anecdotes.
Moms are encouraged to strut their stuff and wear their finest Mother's Day hats for the Best Hat Contest! Of course, there will be prizes.
If you have a guest that is 12 and under that would like to attend, please click here to purchase a youth ticket.
Event Menu
Welcome mimosa plus..
Pan of Schnecken
(which are similar to cinnamon rolls- from Grandma Douglas' famous recipe!)
Plate of Scones
Fruit Cup
Three Course Brunch Menu with Demos by Tom Douglas:
1st: +Spring Peas Please: Sugar Snap Peas, Pea Tendrils, Chilled English Pea Soup
2nd: Dungeness Crab Quiche with Crispy Morel Mushrooms, Smoky Bavarian Meats Bacon, Arugula, Lemon Pressed Olive Oil
3rd: Strawberry Rhubarb Cobbler, Vanilla Bean Gelato
Menu Note: We will not be able to accommodate any menu substitutions


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Musician from Russia, Saint-Petersburg
A picture of my life.
Thinking of despair.. that awful feeling in a winter night
Cat selfie
Dawn must come.
When summer ends :(
Back to the hometown for some time
Who's the highest one of all :D
Yes, I'm fooling around
"When you have nothing to do"
Can anyone recognize who's that?
Another drummer from hell.
I'm a sick drummer!
Oh yes! It was slooow, but I've finally received it, been waiting for a year.
The first time I observed process of making a music video. Cool!
VIP drum performance, only for me :D
Muse Tribute
An evening without electricity in absolute lonliness and the notebook is discharged..
Autumn <3
Preparing for our Muse Tribute show
Learning to drive
Youtube, it's not funny, stop it now!
Watch my new cover on YouTube in half an hour! ; )
Hedgehogs follow me everywhere! Maybe it is my fate..
All my stuff right now
Yes! Finally I'll see Muse in June!
Found a Russian magazine with my interview
Fuck! Even better.
Only true guitarists can understand how it feels
Just killed someone.
Miss that place very much
Trying the bass
Cool band :D
Because! I don't care! Fuck you :D
New instrument :D
Line 6 POD HD500x. Yeeeah this is my Birthday present from me to myself :D thanks! #happy
Still love this this guitar even if it sounds not so cool *_*
Me and my new Gibson Les Paul Futura walking together :D
Guitarists only
#vrox #vrox14 #rock #gibson
Copyright © 2019 Pikinta. All Rights Reserved.


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Open Access This article is
- freely available
- re-usable
Life 2018, 8(4), 38; https://doi.org/10.3390/life8040038
Controlled Construction of Stable Network Structure Composed of Honeycomb-Shaped Microhydrogels
RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo 650-0047, Japan
Department of Computer Science, School of Computing, Tokyo Institute of Technology, Yokohama, Kanagawa 226-8502, Japan
School of Materials Science, Japan Advanced Institute of Science and Technology, Nomi, Ishikawa 923-1292, Japan
Department of Mechanical Engineering, Keio University, Yokohama, Kanagawa 223-8522, Japan
Author to whom correspondence should be addressed.
Received: 21 August 2018 / Accepted: 16 September 2018 / Published: 20 September 2018
Recently, the construction of models for multicellular systems such as tissues has been attracting great interest. These model systems are expected to reproduce a cell communication network and provide insight into complicated functions in living systems./Such network structures have mainly been modelled using a droplet and a vesicle. However, in the droplet and vesicle network, there are difficulties attributed to structural instabilities due to external stimuli and perturbations. Thus, the fabrication of a network composed of a stable component such as hydrogel is desired. In this article, the construction of a stable network composed of honeycomb-shaped microhydrogels is described. We produced the microhydrogel network using a centrifugal microfluidic technique and a photosensitive polymer. In the network, densely packed honeycomb-shaped microhydrogels were observed. Additionally, we successfully controlled the degree of packing of microhydrogels in the network by changing the centrifugal force. We believe that our stable network will contribute to the study of cell communication in multicellular systems.
Keywords:cell communication; artificial cell/tissue; microhydrogel network; microfluidics
1. Introduction
In a living multicellular system, such as tissue, sophisticated functions are realized via the organization of individual cells. Recently, the experimental construction of models for living multicellular systems has attracted considerable interest. The use of such model systems allows the extraction of the essence of highly orchestrated but complicated functions in living systems, and helps to understand them. In particular, recent development of a network model system that is useful for understanding cell communications has been remarkable. Cell communication is essential for many important and vital functions in biological systems. For example, gap junctions perform the exchange of small molecules and ions, which is vital for homeostasis maintenance [1,2]; cell communication through molecular diffusion is an important factor in the pattern formation of skin [3,4]. Using diffusively-connected networks of droplets, various pattern formations [5,6], chemical communications via quorum signalling molecules [7], and a differentiation process [8] have been investigated. In the surfactant bilayer network [9] and networks of aqueous droplets [10,11], the construction of pore-connected pathways conducting an electric current was demonstrated. Furthermore, a three-dimensional (3D) network composed of lipid-coated aqueous droplets was realized using 3D-printing technology; the self-folding of droplet networks was demonstrated by an osmotic interaction between droplets [12]. Further, although the network size is not large, recently, the construction of vesicle networks has been in development [13,14]. Currently, droplet and vesicle networks are an important platform for understanding the communication in living multicellular systems. However, because the contact boundaries of the droplets or the vesicles are unstable, problems such as unexpected coalescence due to external factors, e.g., electric current, and the difficulty of handling the network, cannot be neglected. Challenging studies reported a network that was embedded in an organogel block to stabilize the whole network structure [15], but the problem of instability at the boundary between droplets remained. Another group proposed highly-stable communicating droplets encapsulated in a hydrogel [16]. However, it is difficult to construct a network structure as large as a living multicellular system, because the size of the hydrogel encapsulating the droplet is in the millimeter scale. Hence, previous studies have not succeeded in the construction of a network model for multicellular systems with stability against external stimuli. To achieve this, construction of a micrometer-scale network model composed of a stable component (e.g., hydrogels) is required. Here, we propose a fabrication method for a network structure composed of stable honeycomb-shaped microhydrogels. Our method can control the size and packing degree of each honeycomb-shaped microhydrogel. In this paper, we first describe the fabrication of the honeycomb microhydrogel network with the control of the size and the packing degree. In addition, molecular diffusion among the honeycomb-shaped microhydrogels was investigated. Finally, the fabrication of a triple-layered honeycomb microhydrogel network and a network composed of double-faced honeycomb microhydrogels was demonstrated. The method described in this paper will be useful for constructing a sophisticated experimental model and understanding the essence of cell communication in living systems.
2. Materials and Methods
2.1. Materials and Experimental Setup
We constructed the honeycomb microhydrogel network using a centrifuge-based microfluidic device [17,18] and a photosensitive polymer solution. The microfluidic device consisted of a theta-shaped glass capillary (TST150-6, World Precision Instruments, Sarasota, FL, USA), a capillary holder, and a sampling microtube (1.5 mL microtube CF-0150, BIO-BIK, Osaka, Japan) (Figure 1a). The glass capillary and the capillary holder were processed according to a previously reported study [17,18]. In this study, the orifice diameter of a tip of the theta-shaped glass capillary was tuned to 30 μm (Figure 1b). The tuned theta-shaped glass capillary was used in all experiments to standardize experimental conditions. The inside of the glass capillary was filled with a photosensitive polymer solution comprising 34% (v/v) polyethylene(glycol) diacrylate (PEGDA) (Mn = 700) (ALD455008, Sigma–Aldrich, St. Louis, MO, USA), 6% (v/v) 2-hydroxy-2-methylpropiophenone (Darocur) (ALD405655, Sigma–Aldrich), and 2.4% (v/v) glycerol (075-00616, Wako Pure Chemical Industries, Osaka, Japan). In addition, depending on the experiment, a fluorescein sodium salt (F6377, Sigma–Aldrich), a dispersion of red-fluorescent microbeads (Fluoresbrite Carboxylate Microspheres 0.10 μm NYO, Polyscience, Inc., Warminster, PA, USA), and green-fluorescent microbeads (Fluoresbrite Carboxylate Microspheres, 0.10 μm YG, Polyscience, Inc.) were added to the photosensitive polymer solution. Although the fluorescent microbeads sometimes aggregated in the photosensitive polymer solution, the aggregates did not affect the formation of the honeycomb microhydrogel network. The sampling tube was filled with 170 μL of mineral oil (23334-85, Nacalai Tesque, Inc., Kyoto, Japan) containing a surfactant: 3% (v/v) ABIL EM 90 (Evonik Degussa Japan Co., Ltd., Osaka, Japan).
2.2. Fabrication and Analysis of Honeycomb Hydrogel Network
Figure 1c–e shows the fabrication of the honeycomb microhydrogel network. To enable fluorescence observations, the fluorescein sodium salt was added to the photosensitive polymer solution (final concentration: 1 mM), and they were introduced on both sides of the theta-shaped glass capillary. The assembled microfluidic device was placed in a swing rotor centrifuge (ATT 101, HITECH Co., Ltd., Tokyo, Japan) (Figure 1c) and subjected to a centrifugal force FG (1183× g) for 1 min under ultraviolet (UV) light irradiation (λ = 365 nm) (lamp: HLR100T-2, power supply: HB100A-2, SEN LIGHTS Co., Ltd., Osaka, Japan) from the top of the centrifuge. Under FG, droplets of the photosensitive polymer solution were formed at the tip of the capillary, and were discharged toward the bottom of the sampling tube through air and oil phases (Figure 1d,e). To avoid the solidification of the photosensitive polymer solution in the glass capillary, all but the bottom of the sampling tube was wrapped by aluminium foil (Figure 1d,e).
The honeycomb microhydrogel network was removed from the sampling tube using tweezers, and observed using confocal laser scanning microscopy (CLSM) (FV 3000, Olympus Co., Tokyo, Japan). The area of the honeycomb-shaped microhydrogel Sgel and the gap area between them Sgap were manually measured using the software Image J (National Institutes of Health, New York, NY, USA, 2015, 1.50a). We defined a size parameter d to characterize the size of the honeycomb-shaped microhydrogel; d was calculated using d = 2(Sgel/π)1/2.
The triple-layered honeycomb microhydrogel network was constructed by stacking layers of honeycomb microhydrogel networks. After the fabrication of the first layer of the honeycomb microhydrogel network, the glass capillary was changed. Then, the second honeycomb microhydrogel network was fabricated on the first layer. Finally, the third layer was fabricated in the same way. To clearly confirm the layer boundaries, each honeycomb microhydrogel network was fabricated using the photosensitive polymer solution containing different fluorescent microbeads (first layer: 0.45% (v/v) green-fluorescent microbeads and 0.045% (v/v) red-fluorescent microbeads; second layer: 0.5% (v/v) red-fluorescent microbeads; third layer: 0.5% (v/v) green-fluorescent microbeads). Here, we blended the green- and red-fluorescent microbeads to generate a yellow fluorescence color for the first layer.
A double-faced honeycomb microhydrogel network was constructed using the glass capillary with different solutions in each compartment of the theta-shaped capillary. Here, both compartments of the capillary contained the photosensitive polymer solution with 1% (v/v) sodium alginate (196–13,325, Wako Pure Chemical Industries), and these solutions were colored by adding 0.25% (v/v) fluorescent microbeads (green and red). The Reynolds number decreased owing to an increase in the viscosity as a result of the addition of the sodium alginate. This prevented the photosensitive polymer solution in each compartment of the discharged droplet from mixing together.
2.3. Experiment and Analysis of Fluorescence Recovery after Photobleaching (FRAP)
FRAP analysis was performed in the condition of a non-gel aqueous solution, a non-compartmentalized bulky hydrogel, and the honeycomb microhydrogel networks using a FRAP system integrated in the CLSM. Here, the fluorescein sodium salt was used as a fluorescence molecule. We examined the diffusion of the fluorescence molecule in the Milli-Q water (Merck KGaA, Darmstadt, Germany), the bulk hydrogel, and the honeycomb microhydrogel network. The Milli-Q water contained 10 mM fluorescein sodium salt. Both the hydrogels were fabricated using identical photosensitive polymer solution (as described in Section 2.1) containing 10 mM fluorescein sodium salt. The bulk hydrogel was prepared via 1 min of homogeneous UV irradiation to 7.5 μL of the photosensitive polymer solution in the sampling tube. The honeycomb microhydrogel network was fabricated under FG = 1183× g. In the Milli-Q water and the bulk hydrogel, the fluorescence was circularly bleached with a radius of 50 μm, whereas in the honeycomb microhydrogel network, the fluorescence of the whole area of one of the honeycomb-shaped microhydrogels was bleached. After the photobleaching, fluorescence recovery was observed for 5 min, and the fluorescence intensity I at each time t was measured. The normalized fluorescence intensity at each time was defined as In (t) = I(t)/I(0). The FRAP experiment were performed three times in each condition, and the mean values of In (t) were calculated at each t.
3. Results and Discussion
3.1. Fabrication of Network Structure
Figure 2a shows the sampling tube immediately after the fabrication of the honeycomb microhydrogel network. At the bottom of the sampling tube, a layer composed of stacked microhydrogels was observed (orange rectangle in Figure 2a). Figure 2b,c show CLSM images of the honeycomb microhydrogel network; a densely packed network structure composed of honeycomb-shaped microhydrogels was observed.
It is speculated that this honeycomb microhydrogel network was formed by the balance between the time for the polymerization and the FG-induced deformation of the droplet at the bottom of the sampling tube. When FG was applied, a sphere packing structure composed of the droplets was formed in a two-dimensional plane on the bottom of the sampling tube. Because it takes a certain time for polymerization, most of the droplets in the packing structure were incompletely polymerized. Since the elasticity of the moderately polymerized droplets was small, they underwent deformation by FG and lateral contact with neighboring droplets as the density of the droplets in the packing structure increased. After a maximum density was achieved, another sphere packing structure was formed on the existing packing structure, and each droplet in the sphere packing structure deformed in the same manner. Eventually, the droplets were completely polymerized, resulting in the formation of the honeycomb microhydrogel network.
The shape of the microhydrogels outside the broken line was not a perfect honeycomb-shape (Figure 2b). This imperfection is considered to be due to the excessive deformation of droplet. When the droplet was introduced in the existing sphere packing structure, the droplet collided with the moderately polymerized droplets in the packing structure. Because the droplet was in the liquid state immediately after it was introduced into the structure, the droplet could undergo excessive deformation, and this could induce incomplete honeycomb-shape formation. Another possibility could be that the imperfect honeycomb-shape was imaged because the stacked microhydrogel did not exist in the same plane.
3.2. Control of Structure in Hydrogel Network by Changing Centrifugal Force
As shown in Figure 2, it is speculated that one of the factors of the honeycomb packing was FG-induced deformation. Hence, we demonstrated the control of the hydrogel network structure by changing FG. We fabricated the honeycomb hydrogel network under FG = 67,312, and 1183× g, as shown in Figure 3a–c, respectively. From those CLSM images of the hydrogel network under each FG, the area Sgel, the gap area Sgap and the size parameter d of the individual hydrogel were obtained. In the lower images in Figure 3a–c, Sgap are colored blue. Histograms of d in FG = 67,312, and 1183× g are shown in Figure 3d, indicating that size distributions were narrow in each FG. We attributed this size controllability to our centrifuge-based microfluidic device [17,18]. As shown in Figure 3e, the mean of size parameter <d> decreased as FG increased, indicating that the size of the hydrogels in the network structure was well controlled. In the condition of FG = 1183× g, the droplet-discharging frequency was high. In this situation, more droplets can be additionally introduced in the packing layer, which increased the force of the lateral contact. As a result, <d> decreased.
On the other hand, when FG = 67× g, the droplet-discharging frequency was low. In this case, it is speculated that most of the droplets polymerized completely before the formation of the sphere packing. Because the completely polymerized droplets cannot be deformed, additional droplets were not packed in the existing layer. As a result, <d> was larger than <d> in FG = 1183× g. Furthermore, to analyze the relationship between FG and the degree of packing, we measured the gap area Sgap (blue areas in Figure 3a–c), and R = Sgap/Sgel was defined. As shown in Figure 3f, R decreased as FG increased, indicating that R was also controlled by changing the applied FG. We attributed this controllability of the network structure to the stability of the hydrogel. As previously indicated, the network structure was controlled using the deformation of the individual microhydrogels. The hydrogel stably retained its shape as it solidified, and the packing degree of the constructed network was thus well controlled.
3.3. Inhibition of Molecular Diffusion in Honeycomb Hydrogel Network
We performed FRAP analysis to test whether our network structure can be applied to the model of the multicellular system, i.e., whether the contents can be confined within each individual honeycomb-shaped microhydrogel, as in living cells. Here, we show that the honeycomb-shaped microhydrogel in the network inhibited molecular diffusion. CLSM images of photobleaching at t = 0 s and recovery at t = 295 s in each medium are presented in Figure 4a–c (a: the non-gel aqueous solution, b: the non-compartmentalized bulky hydrogel, c: the honeycomb microhydrogel network). In each image, the photobleached area is enclosed by a red line. Figure 4d shows fluorescent recovery curves obtained from each experiment (green: the non-gel aqueous solution, red: the non-compartmentalized bulky hydrogel, blue: the honeycomb hydrogel network), and the error bars depicted in 11.1 s intervals represents the standard deviation. It is obvious that In(t) recovered the most quickly in the non-gel aqueous solution. In(t) of the non-compartmentalized bulky hydrogel rose more rapidly than that in the honeycomb microhydrogel network. This difference means that the molecules in the non-compartmentalized bulky hydrogel diffuse faster than those in the network. In other words, the molecular diffusion was hindered by the boundary of the honeycomb-shaped microhydrogel in the network, and we consider that most molecules will be trapped in the honeycomb-shaped microhydrogel. Nevertheless, slight molecular diffusion was observed from the outside of the honeycomb-shaped microhydrogel.
FRAP analysis yielded the observation that the diffusion of the molecules in the honeycomb microhydrogel network was slight and slow compared with the bulk hydrogels. If larger molecules are used, the molecules can be confined in the honeycomb-shaped microhydrogel. Our honeycomb microhydrogel network has the potential to provide a communication network based on the diffusion of small molecules synthesized by larger molecules confined in each honeycomb-shaped microhydrogel. Because each microhydrogel was densely packed and in close contact, the small molecules diffusing out of the microhydrogel would directly reach the neighboring microhydrogel and trigger synthesis reactions. Therefore, it would be possible to set up diffusion-based molecular communication, e.g., a network composed of the honeycomb-shaped microhydrogel that encapsulates cells itself and cell-free gene expression systems. In addition, in this network, the frequency of communication among the honeycomb-shaped microhydrogels could be controlled by controlling the packing degree (Figure 3), because the time of molecular diffusion is generally affected by the medium. In particular, when R is large (Figure 3a, FG = 67× g), because there are many gaps between each microhydrogel, communication like quorum sensing [19] may be observed.
Cytotoxicity due to UV irradiation during the construction cannot be avoided when constructing a network including cells and biomolecules. However, it could be minimized by optimizing the experimental parameters, including the UV power and the concentration of the photosensitive polymer solution, or by using photosensitive polymers that can be solidified using a longer wavelength of light.
3.4. Fabrication of Triple-Layered Honeycomb Hydrogel Network
Figure 5a shows the construction of the triple-layered honeycomb microhydrogel network (left: single layer, middle: double layer, right: triple layer). The triple-layered structure was constructed as Figure 5a. The insets show fluorescent colors (upper) and simplified diagrams of the layered honeycomb microhydrogel network (lower). The boundaries and middle positions of layers are shown in Figure 5b. The upper panel shows CLMS images, and the black arrows in the lower illustrations show the observed position of the triple-layered structure. In the CLMS observation, a zy-plane of the cut triple-layered structure was observed. These images indicate that the boundaries were formed; thus, by the stacking of each layer, we successfully fabricated the triple-layered honeycomb microhydrogel network. On the other hand, in the second layer (red), the honeycomb packing did not form clearly, as compared with the other layers. This incompleteness may be attributed to the excessive deformation of the droplets, as discussed for the results in Figure 2b.
We consider that the first layer in the second left CLMS image in Figure 5b looked green because the aggregation of fluorescent beads was formed in the photosensitive polymer solution, resulting in a non-uniform fluorescent color. In addition, although the boundary of the layer appeared yellow (the second and fourth left CLMS images in Figure 5b), we speculate that this was because the color of the upper and lower layers overlapped.
This triple-layered honeycomb microhydrogel network was sufficiently stable and did not break, even when it was manipulated using a tweezer (Figure 5c). This stable network will enlarge the range of experiments. For example, a dynamic and quick change of the environment surrounding the network could be easily achieved by transferring the network to another solution using a tweezer.
The triple-layered honeycomb microhydrogel network has the potential to reproduce the cell communication in multi-layered living tissue, such as blood vessels and skin. These tissues consist of layers formed by different cells, each of which has a different role. By stacking a variety of network layers, for example, layers including different functional molecules and cells, a multi-layered network with different functions can be constructed. Besides, the thickness of each layer can be controlled by the duration of centrifugation.
3.5. Fabrication of Network Structure Composed of Double-Faced Honeycomb Hydrogels
The fabrication of the network structure composed of double-faced honeycomb hydrogels is demonstrated in Figure 6a,b. It was confirmed that each of the honeycomb-shaped microhydrogels in the network was compartmentalized in two parts—the part containing red fluorescent microbeads and the part containing green fluorescent microbeads—as clearly shown in the high-magnification image (Figure 6b). Also, this demonstration suggests that a network composed of the multi-compartmentalized honeycomb-shaped microhydrogel with more than two compartments, may be realized using glass capillaries with more than two compartments [17,18].
The construction of the network composed of the multi-faced honeycomb-shaped microhydrogels is valuable. Such heterogeneous features are widely observed in biological systems. For example, epithelial cells exhibit spatial heterogeneities of channel proteins for efficient molecular transport. Honeycomb-shaped microhydrogels made heterogeneously from solutions with different concentrations could be used to realize a network with a heterogeneous diffusion profile. Furthermore, a combination of the multi-layered (Figure 5) and multi-faced (Figure 6) honeycomb microhydrogel network will be an ideal platform for mimicking the sophisticated functions of tissues.
4. Conclusions
We showed the controlled fabrication of the honeycomb microhydrogel network, and demonstrated the high stability and the suppression of molecular diffusion in the network. We constructed the honeycomb microhydrogel network utilizing the centrifugal force and the photopolymerization. In this method, moderately polymerized droplets were packed and deformed by FG, and were then completely polymerized, resulting in the formation of a honeycomb microhydrogel network with high stability. We also demonstrated the control of the network structure by changing FG. As we increased FG, the size of the individual honeycomb-shaped microhydrogels decreased, and the degree of packing increased. Additionally, it was confirmed that the molecular diffusion in the honeycomb microhydrogel network was inhibited by comparison with the bulk hydrogel. We also demonstrated the two types of fabrications of honeycomb microhydrogel networks with more complex structures. First, we fabricated the triple-layered microhoneycomb network, which had the distinct boundary of the differently fluorescent colored layers. A network composed of the honeycomb-shaped microhydrogel with two compartments was also fabricated.
The honeycomb microhydrogel network demonstrated in this study was stable enough to be handled directly with a tweezer (Figure 5). Because a lipid bilayer behaves as a semipermeable membrane, the vesicles are sensitive to osmotic pressure [20,21]; thus, it is not easy to control the structures after the reaction in the vesicle network. In the droplet network, even the droplets were coated with lipids, and unexpected fusion sometimes occurred when an electric voltage was applied [9]. Contrary to these cases, because our network was composed of the hydrogel, the structure of each microhydrogel cannot be broken by osmotic pressures or applied voltage, etc. We believe that our highly-stable honeycomb-shaped microhydrogels network will help to elucidate functions of living multicellular systems orchestrated by cell communications.
Author Contributions
Conceptualization, M.H., S.U., K.H.N., H.O. and M.T.; Formal analysis, S.U.; Investigation, S.U.; Methodology, M.H., S.U. and M.T.; Project administration, M.T.; Supervision, M.T.; Visualization, M.H.; Writing—original draft, M.H. and M.T.; Writing—review & editing, M.H., S.U., K.H.N., H.O. and M.T.
We thank Masamune Morita (AIST) for helpful discussions. This work was supported by JSPS KAKENHI Grant Numbers 18K19834, 17H01813 to Masahiro Takinoue.
Conflicts of Interest
The authors declare no conflict of interest.
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Figure 1. Centrifuge-based microfluidic device and fabrication scheme of the honeycomb microhydrogel network. (a) Setup of the centrifuge-based microfluidic device. The microfluidic device consisted of the theta-shaped glass capillary, the capillary holder and the sampling microtube. (b) Illustration of the theta-shaped glass capillary. A partition exists inside the capillary. The orifice diameter was tuned to 30 μm. (c) The device in the centrifuge. The orange circles indicate the device wrapped by aluminum foil. (d) Schematics of the fabrication of the honeycomb microhydrogel network. The centrifugal force FG was applied to the assembled microfluidic device under UV irradiation from the top of the centrifuge. The honeycomb microhydrogel network was formed at the bottom of the sampling tube. (e) Formation and discharging of the droplet under the UV irradiation. Owing to FG, the photosensitive polymer solution in the glass capillary was dripped and discharged to the air phase. In the glass capillary, the polymerization of the photosensitive polymer solution was inhibited because of the partial protection of the UV irradiation.
Figure 2. Observation of the honeycomb microhydrogel network. (a) Honeycomb microhydrogel network that accumulated at the bottom of the sampling tube (orange rectangle). (b) CLSM images of the honeycomb microhydrogel network. Many of the microhydrogels had the honeycomb shape and were densely packed. (c) Enlarged image of the dashed squared area in (b).
Figure 3. Control of the structures of the microhydrogel in the network by changing FG. (a–c) CLSM images of the honeycomb microhydrogel network fabricated under various values of FG. The applied FG was 67× g (a), 312× g (b), and 1183× g (c). Lower images are magnified images. Sgap corresponds to the blue area in the lower images. It was speculated that the green puncta in the image of FG = 67× g (a) were the emulsions of exuded fluorescein sodium salt solution from the microhydrogel. (d) Histograms of <d> of each FG. (e) Control of <d> by changing FG. <d> was decreased by increasing FG. (f) Control of R by changing FG. R was decreased by increasing FG.
Figure 4. FRAP analysis in the honeycomb microhydrogel network. (a–c) Frames of the movie of the fluorescence recovery. FRAP analysis was performed in (a) the non-gel aqueous solution, (b) the non-compartmentalized bulky hydrogel, and (c) the honeycomb microhydrogel network fabricated under FG = 1183× g, and the fluorescence recovering was observed for 5 min. The area enclosed by the red line is the photobleaching area. The numbers near each area were for analysis. (d) Time course of In(t). In(t) of the honeycomb microhydrogel network (blue curve) had a longer recovery time than that of the non-gel aqueous solution (green curve) and the non-compartmentalized bulky hydrogel (red curve).
Figure 5. Fabrication and observation of the triple-layered honeycomb microhydrogel network. (a) Fabrication process of the triple-layered honeycomb microhydrogel network. Initially, the first layer was formed at the bottom of the sampling tube (left). Then, the second layer was formed on the first layer (middle). Finally, the third layer was formed on the second layer (right). All layers were fabricated under FG = 1183× g. Upper insets: fluorescence coloring of the layers. Lower insets: simplified diagram of the layered honeycomb microhydrogel network. (b) CLMS images of the zy-plane of the cut triple-layered honeycomb microhydrogel network and illustrations of the observed position. The images in the upper panel are CLMS images of the zy-plane of the triple-layered structure. The observed position in the triple-layered structure is shown by the black arrows in the illustrations of the lower panel. (c) Direct handling of the triple-layered honeycomb microhydrogel network. The network was easily handled by a tweezer.
Figure 6. Observation of the network structure composed of the double-faced honeycomb-shaped microhydrogels. (a,b) CLSM images of the network. Each of the honeycomb-shaped microhydrogels in the network was compartmentalized in two parts. Applied FG was 1183× g.
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).


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04:22AM, Tuesday 04 December 2012
No action has been taken by police against a Berkshire man in his 80s interviewed under caution as part of a post Jimmy Savile investigation.
The man attended a south London police station by appointment on Thursday and left the station the same day.
A Metropolitan Police spokesman said he was interviewed under caution by officers working on Operation Yewtree and had not been asked to return for further questioning.
The force executed a search warrant at an address in Berkshire on Saturday last week.
Operation Yewtree is a police investigation into alleged child sexual exploitation by the late Jimmy Savile and others, which started in October.
Most Recent
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Police are investigating two 'suspicious incidents' in Maidenhead where a woman approached young children.
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text:
patterns > Cindy de Vries' Ravelry Store
> Tool belt
Tool belt
This tool belt is a necessity for anyone who want to dress up as a builder.
The tool belt can be adjusted to accommodate different waist measurements and the pattern can easily be adjusted to different tools.
The pattern consists of written instructions (US and UK terminology) for making the belt and guidelines on how you make the tool belt to fit the required waist measurement. The belt is worked flat and a little bit of seaming is involved. Gauge doesn't matter as the belt can be made to measure while making it. I used dk yarn (251.9 m/275.5 yd) and a 5.0 mm (H) hook to make a belt for a 57 cm/22.4" waist.
For this pattern you require:
- DK yarn
- 5.0 mm (H) hook
- 9 buttons
- Tapestry needle
Feel free to contact me if you have any questions or find any mistakes.
Feel free to sell the tool belts you make, but please don't sell the pattern or claim it as your own.
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NEWS6 September 2010
NEWS6 September 2010
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Resverlogix Provides Research and Development Update
News Oct 06, 2015
Resverlogix Corp. has announced that the Resverlogix clinical and science teams, along with two members of the international clinical steering committee for the upcoming BETonMACE study, presented a Research and Development Update for RVX-208 "apabetalone" on September 25, 2015 in New York City.
Highlights from the presentation included an in depth analysis of the large unmet medical need in diabetes patients at high risk for secondary major adverse cardiovascular events ("MACE") presented by the chair of the BETonMACE clinical steering committee, Professor Kausik K. Ray, BSc , MBChB, MD, MPhil, FACC, FAHA, FESC, FRCP.
In addition, a breakdown of the unmet medical need in Chronic Kidney Disease and the therapeutic potential of apabetalone in this indication were presented by clinical steering committee member, Dr. Kamyar Kalantar-Zadeh, MD, MPH, PhD, FAAP, FACP, FASN, FAHA, FNKF.
Senior Vice President of Clinical Development, Dr. Mike Sweeney, MD detailed the final design of the BETonMACE clinical trial, and Vice President of Scientific Development, Dr. Ewelina Kulikowski, PhD highlighted novel biology and findings from ongoing mechanistic studies focused on cardiovascular risk pathways and apabetalone's potential in reducing MACE.
Kenneth Lebioda, Senior Vice President of Business and Corporate Development finished with a discussion of findings from primary market research focusing on primary care physician and payer perceptions of apabetalone.
New evidence published in the Cochrane Library provides high quality evidence that people who use a combination of nicotine replacement therapies (a patch plus a short acting form, such as gum or lozenge) are more likely to successfully quit smoking than people who use a single form of the medicine.READ MORE
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Mayor Drops Plans To Close London Overground Ticket Offices
The title of this post is the same as that of this article on the BBC.
This is the first two paragraphs.
The Mayor of London has dropped plans to close ticket offices at 51 London Overground stations.
Busy stations will continue to operate as usual, though many will have opening hours reduced to just two-and-a-half hours per day, City Hall said.
Although the Unions objected to the Mayor's original plans and this has probably prompted the Mayor's U-turn, I think that staff in ticket offices will disappear within perhaps five years.
The only time, I see anyone use the Ticket Office at Dalston Junction station, is probably to sort out a ticketing issue with the machines, which are becoming increasingly rare, as Transport for London are increasing their numbers and replacing older machines with better designs.
Also as Dalston Junction is a busy station, there is usually someone manning the gate-line, who can help.
But over the next few years, the following will happen.
- More and more passengers will use contactless ticketing with bank cards.
- Contactless ticketing will expand widely, so that for most journeys in the UK, you would just touch-in and touch-out.
- Oyster will cease to be used and be withdrawn.
- Gateline technology will get better.
- Staff working on the gateline and platforms, will be better equipped with mobile technology to sort out problems.
- Ticket machines will develop into sophisticated multi-language help points.
- Cash will disappear from daily life and stations.
- Train companies will continue to be short of drivers and will look for other staff that can be retrained.
On a related note, increasingly, London Underground and Overground are being targeted by organised gangs of beggars. This means they need more staff on the gateline to control the problem.
I can see a time, when working in a ticket office will be a very lonely and boring job, that no-one will want to do.
So like the dinosaurs, they will just die out!
Rip-Off Ticketing At Bremen Hauptbahnhof
I am experienced user of Deutsche Bahn and generally buy my tickets at one of their reliable machines.
Note that queuing up at a Ticket Office sometimes takes up to thirty minutes and quite frankly I have better and more important thingfs to do with my life.
This picture shows a typical German ticket.
The two stations; Buxtehude and Cuxhaven are clearly shown.
But imagine my surprise at Bremen Hauptbahnhof, when the ticket machine dispensed this.
It is about one by four centimetres and the only readable writing on the front is EErw.
- Does it look like a ticket to you?
- There were no notices up about the change of ticket.
- How do you sort out today's ticket from yesterday's?
- What if you're partially sighted?
I thought the machine had failed and curt off the ticket early.
So I tried again. With the same result!
I then tried the Ticket Office for an explanation, but the guy just played stumm, as Deutsche Bahn employees always do, when they know, there's been a customer relations failure.
I did ascertain, that I had to put the ticket in a machine to validate it before travelling.
I did think about not doing this, so that I would get arrested on the train, but in the end, I can't remember whether I did.
However, as tickets were not checked on the train, it didn't matter.
It is the most arrogant system of ticketing I've ever found.
When I got home, I found I had been charge for two tickets.
My bank;Nationwide are trying to refuse one of the psyments.
I'll update this post, to give you the result of their argument.
Monetarising The Freedom Pass
I find my Freedom Pass extremely valuable and I'm extremely grateful for it, as I can't drive after a serious stroke, that left me with eyesight problems.
But I feel Freedom Pass use could be expanded, to improve the efficiency of London's transport network and generate some much needed cash flow for Transport for London.
Some Principles
What I am proposing here will obey these principles.
- Charges will only occur, when the card is used in conjunction with a bank card to buy tickets or services.
- Any tickets or services bought through the Freedom Pass system, will be at the best possible price.
But the major principle will be that if a Freedom Pass holder continues to use their card as they do now, they will not pay any charges.
An Updated Web Site
The current web site at www.freedompass.org is mainly for information only.
This function could be increased, but I also think the website could be extended in several ways.
A Personal Profile
Some pass holders might like to add a personal profile with perhaps a photograph and selected personal details, next of kin and some medical details.
Obviously, creating a profile would be at the pass holder's discretion.
Journey Logging
I believe that with Oyster, you can check where you've been on a ticket machine.
Some Freedom Pass holders might like to have a similar facility on a web site.
Railcard Management
If you have a Freedom Pass, the site will know if you are over a certain age or have a qualifying disability. I would actually get a Freedom Pass, even if I wasn't quite as old, as my eyesight was deemed not good enough to drive.
So the Freedom Pass web site could prompt you when you needed to renew your Railcard.
Adding A Bank Card To A Freedom Pass
To get between Dalston Junction and Gatwick Airport stations, I need to buy a ticket from the Zone 6 Boundary to the Airport. It would be very handy, if a Freedom Pass could be linked to a bank card, so that there was no need to buy an extra ticket. The few pounds to get to the Airport, would be automatically charged to the linked bank card.
I would not need to buy a ticket and would just touch in at Dalston Junction station and touch out at Gatwick Airport. My bank card would be charged a few pounds.
The link would also work, where a journey was done before the 09:30 start time of Freedom Pass on many routes.
So if Esmerelda, who lived in Camden wanted to get to Orpington to walk her grandchildren to school., she would be able to use the Freedom Pass for a normal fare, which would be charged to her bank card.
I would assume that Transport for London would pick up a small commission for the National Rail tickets.
A Ticket Buying Web Site
Depending on the company, the rules for using Freedom Passes with National Rail tickets aren't always simple.
Yesterday, I went to football at Ipswich and bought a return ticket between Harold Wood and Ipswich stations.
- Harold Wood is the Zone 6 boundary.
- I was also able to get on a Liverpool Street to Norwich train, despite it not stopping at Harold Wood.
- As a Greater Anglia ticket inspector told me off for not doing this about six months ago, when he saw my Freedom Pass alongside my Senior Railcard, when he checked my tickets, I feel it must be right.
But I don't think all train companies are so accommodating.
Suppose you were able to buy any rail ticket on the Freedom Pass web site and I wanted to buy a return ticket on a Saturday from Dalston Junction to Ipswich.
- Logging in, the site would know I had a Freedom Pass and a Senior Railcard.
- I would ask for my ticket and then the web site would find my cheapest ticket.
- I would pay for it as one does on any of the numerous rail ticket web-sites.
But it would probably add a third orange ticket, giving my route and conditions.
Should Ticket Buying Be Limited To Freedom Pass Holders?
If you are a London resident, would you use a trusted ticket buying web site from Transport for London, where you knew any profits would be reinvested in London's transport network?
If it was a best price, I would!
The right design of web site could be a nice little earner for Transport for London.
Or any other regionalised transport organisation, like Transport for Wales or Merseytravel.
Would Third-Party Rail Ticket Machines Be A Good Idea?
I travel extensively on the UK rail network and my journeys are generally of three types.
- Local journeys within the London Zone 1-6 Travelcard area, for which I use my Freedom Pass.
- Journeys to places like Brighton, Hastings, Ipswich and Rochester, where I generally buy a ticket from a machine.
- Long distance journeys, where I use the Internet and pick up the ticket at a machine.
I suspect that many travellers across the UK, have a similar pattern of use.
The Changing Nature Of Cash Machines
Forty years ago, there were an adequate number of cash machines, but they were generally associated with bank premises.
I can remember my delight, when I first found a machine in a motorway service area.
Now, cash machines are everywhere and all are free. Although, there are mutterings, that charges might be made and the number of machines will drop, due to contactless cards.
A Third-Party Rail Ticket Machine
At present, the nearest to this are the ticket machines on the London Overground.
The latest ones allow you to do all the normal ticketing functions, with these valuable additions.
- Buying a ticket between any two stations in the UK.
- Buying an extension ticket from the London Zone 6 boundary.
- Prices are generally the lowest you can purchase, on the Internet without using Advance Tickets for specific trains.
These feature means, that if say I'm going to a football match outside London in a few days, I'll buy my ticket from the Overground.
Ticket machines will add more and more features.
- Train information.
- Itinerary printing.
- Buying Advance tickets for a specific train.
- Seat reservations.
- Special tickets like Plus Bus, Plus Tram and Rover and Ranger tickets.
- Selling railcards
Imagine turning up in a city and being presented with a screen on the same machine, which allows you to buy Travelcards and tickets for local attractions.
As the machines get more sophisticated, I believe there will be less need for ticket machines to be at train stations.
So could we see companies like The Trainline putting ticket machines in places like shopping centres, superstores and the smaller shops that service Oyster in London?
If the financial model stacks up, I'm sure we will see ticket machines everywhere!
Ticket Machines On Platforms And In Ticketed Areas
In Germany, there is often a ticket machine after you have passed the gate.
I find it very useful, as they can be used to buy tickets for a later journey or look up future connections.
I only know of one ticket machine inside the ticketed area in the UK and that is on Platform 8 at Stratford station.
We need more of these!
Would a third-party company be more likely to provide them? Especially, as they'd quickly identify the most profitable places, where there were large numbers of interchange or waiting passengers.
Collateral Benefits
Making rail tickets more available will surely increase sales. Suppose you live in Nottingham and your mother lives in Peterborough. You've just had a bad drive across the Midlands to see her for her birthday.
Will a ticket machine in your local superstore, lead youto investigate the trains as an alternative?
If it does, it must surely lead to more passengers on the trains.
Train companies are notoriously bad, at making sure that a weekend service has enough carriages.
Making it easier to buy tickets would surely give them a better estimate of passenger numbers.
But would the train companies make use of the information?
We'll see a lot more ticket machines.
Some will be from third-party operators. Just like cash machines!
I Like This!
This article in the Guardian is entitled Virgin Trains and six other companies agree to sell advance tickets on the day.
This is said,
The Rail Delivery Group (RDG), which represents the train operators and Network Rail, said customers of Grand Central, Greater Anglia, Northern, TransPennine Express, Virgin Trains East Coast, Virgin Trains West Coast and those using the Caledonian Sleeper from London to Scotland can now also buy Advance tickets for many trains on the day of travel.
The price of football has just dropped, as I can buy my ticket to Ipswich on Saturday morning and might make a saving.
Do You Have A Child Approaching Twenty-Four Who Uses Trains?
Martin Lewis came up with this tip on BBC Radio 5.
If a Young Person's Railcard is bough on a three-year basis, it stretches a few months past, their twenty-seventh birthday.
He did say you had to get your dates right!
Between Exeter St. Davids And Exeter Central Stations
Exeter St. Davids and Exeter Central are important stations in Exeter.
- Many services call at both stations.
- The two stations are about five minutes apart by train.
- It takes fifteen to twenty minutes to walk between the two stations.
- Exeter Central station is in the centre of the city and an easy walk to stops and restaurants.
- Exeter St. Davis station is the junction station, where lines to and from the city meet.
The problem is that it is a very stiff walk up the hill from Exeter St. Davids station to Exeter Central station.
What eases matters, is that every few minutes, a train connects the lower St. Davids to the higher Central.
These pictures document a trip between the two stations.
Note the quality of the trains.
When staying in Exeter, if you come by train, make sure you pick a hotel at the best station for your visit.
I stayed in the Premier Inn by the station and met a couple, who were using the Mercure, which they didn't fault.
This map clipped from Wikipedia, shows the stations in Exeter.
My ticket between the two main Exeter stations, cost £1.50 for an Anytime Day Return, but you can't help thinking that the various train companies working in the area are looking at ways of improving the ticketing.
The fact that First Group is now involved in the two main franchises must help.
But as a visitor, who understands ticketing, I found my £6.60 Devon Day Rangers more than adequate.
Reflections On My Journey From Gatwick
After a good night's sleep, it is perhaps worth taking a look at my experience yesterday in getting through and home from Gatwick Airport.
The train problems were hopefully exceptional, but having seen the new plans for Thameslink's services, which make it difficult for anybody in East London to go South, I suspect that these problems will go on for some time.
The trouble with the new Thameslink is that it has no step-free interchange with any of the main North South routes through East London.
East London Line
Currently, you can change at New Cross Gate for Gatwick services, but after Thameslink fully opens, this connectivity will be lost under current plans.
It looks like the best route will be to go to West Croydon station and take the tram to East Croydon.
Bank Branch Of The Northern Line
Currently, the interchange at London Bridge between Northern Line and National Rail is not good, although it is step-free.
Hopefully, it will get better.
But the problem with the Northern Line is that many of the stations need reconstruction for full step-free access.
If the London Bridge interchange is improved and the excessive walking is cut, I could use this route a lot to get to Thameslink from Angel station.
But Angel is not a station for a large case, a wheelchair or a baby in a buggy.
Victoria Line
Many on the Victoria Line go direct to Victoria and get a direct train.
Victroria Line access to Thameslink is currently terrible with the only interchange at Kings Cross being step-free and a very tortuous and long walk.
After Thameslink is fully open, there will be a much easier change at Finsbury Park station.
I'm still not sure that the new fully-open Thameslink will not be without controversy.
There is also a need for a solution to the Freedom Pass problem.
I suspect that savvy passengers will just buy an extension ticket between East bCroydon and Gatwick Airport.
On the other hand, I wouldn't put it past Gatwick Airport to fund the moving of Gatwick Airport into Travel Zone 6, if Heathrow does something unfriendly with Crossrail ticketing. After all, each return ticket costs just £6.


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Intro Drop-in rate $10 / $5 for the second child.
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Current is the rate at which electric charge flows past a point in a circuit. Voltage is the electrical force that would drive an electric current between two points. Definition Current is the rate at which electric charge flows past a point in a circuit. In other words, current is the rate of flow ...
Now you should understand the concepts of voltage, current, resistance, and how the three are related. Congratulations! The majority of equations and laws for analyzing circuits can be derived directly from Ohm's Law. By knowing this simple law, you understand the concept that is the basis for the analysis of any electrical circuit!
The official SI definition for volt uses power and current, where 1 volt = 1 watt (of power) per 1 ampere (of current). This definition is equivalent to the more commonly used 'joules per coulomb'. Voltage or electric potential difference is denoted symbolically by ∆V, but more often simply as V, for instance in the context of Ohm's or ...
Voltage definition, electromotive force or potential difference expressed in volts. See more. ... The voltage of this current was to be stepped up by a transformer. The Library of Work and Play: Electricity and Its Everyday Uses | John F. Woodhull. The voltage at the dynamo remains practically unchanged, and the current varies according to the ...
The greater the voltage, the greater the flow of electrical current (that is, the quantity of charge carriers that pass a fixed point per unit of time) through a conducting or semiconducting medium for a given resistance to the flow. Voltage is symbolized by an uppercase italic letter V or E.The standard unit is the volt, symbolized by a non-italic uppercase letter V.
Voltage is a representation of the electric potential energy per unit charge. If a unit of electrical charge were placed in a location, the voltage indicates the potential energy of it at that point. In other words, it is a measurement of the energy contained within an electric field, or an electric circuit, at a given point.
Voltage and Current. Voltage is an electric force that causes free electrons to move from one atom to another.. Just like water needs pressure to force it through a hose, electrical current needs some force to make it flow. A volt is the measure of electric pressure.Voltage is usually supplied by a battery or a generator.
Voltage definition is - electric potential or potential difference expressed in volts. How to use voltage in a sentence. ... Best Picture Oscar is About More than the Movie," 21 Feb. 2019 The meter measures voltage and amperage (current) in alternating-current and direct-current modes.
• Voltage, as an expression of potential energy, is always relative between two locations, or points. Sometimes it is called a voltage "drop." • When a voltage source is connected to a circuit, the voltage will cause a uniform flow of charge carriers through that circuit called a current.


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Globe NewsWire News Distribution Service
Press Release: U.S. Variable Frequency Drive Market to hit $3 billion by 2025: Global Market Insights, Inc.
- Details
- Category: Globe NewsWire News Distribution Service
11 Feb 2019
- Last Updated: 11 February 2019
- Published: 11 February 2019
- Written by www.GlobeNewsWire.com Press Releases
Selbyville, Delaware, Feb. 11, 2019 (GLOBE NEWSWIRE) --
The Medium-voltage drives segment of U.S. variable frequency drive market, in the current industry scenario have observed growth subject to their wide application across the commercial and industrial establishments. Rapid retrofitting & refurbishment of existing units & solutions in conjunction with industry standards and codes has re-structured the U.S. VFD market dynamics. Increasing fund flow coupled with aligned industrial focus towards the upgradation of traditional technologies will further amplify the industry growth.Global U.S. Variable Frequency Drive Market is expected to surpass USD 3 Billion by 2025, as reported in the latest study by Global Market Insights, Inc. Increasing environmental concerns coupled with the introduction of directives and standards toward energy efficiency will drive the VFD market across the U.S. Ongoing urbanization, rising industrialization, and the shift in focus on effective energy utilization across various industries will augment the industry landscape. Furthermore, government incentives & funds, R&D investments, technological enhancements, and rising demand for advance product portfolio are key factors positively influencing the business scenario.Technological enhancements along with growing demand for energy optimization across electrical components has boosted the incorporation for micro power drives. These units offer precise control of torque & speed with limited maintenance, compact size and high efficiency which in turn will augment the U.S. VFD market. The global infrastructure investments in 2016, valued over USD 79 trillion across large-scale industries including water, energy, telecommunication and transport.Request for a sample of this research report @ https://www.gminsights.com/request-sample/detail/3104
Posted: 2019-02-11 10:00:00
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Home / Sliding Door / fascinating wood sliding patio doors best design that you will love / 96x80 Sliding Patio Door With Blinds Pella Sliding Door Prices Pella Patio Doors With Blinds 3 Panel Sliding Door
Olivia Sliding Door April 23rd, 2018 - 13:01:40
Although the original concept of a folding sliding door dates back over 100 years where they were often used for closing off small storage areas todays folding sliding doors are designed to be high performance energy efficient patio doors using the latest innovative insulation features in both door and glazing construction. Folding sliding doors not only allow wider unobstructed apertures but the increased glass area allows huge flows of natural light to enter the home from the outside which during the colder months will provide efficient use of solar gain to minimise heating costs. Doors are available in a choice of materials including timber, aluminium and PVC-u together with a choice of colours and finishes that will enhance any home.
Built-in wardrobes offer convenience to many households. A built-in wardrobe saves up a lot of space and gives your home a less crowded feel, no matter how small your home is. Another great feature of wardrobes is that they can be fully customized to whatever design you want and need for your house. One of the things you can customize is the door of your wardrobe. Your wardrobe door is bought separately from the built-in wardrobe set. If youre building your wardrobe yourself, its best to shop around for the best door that would fit your wardrobe. Sliding doors are more preferred than the usual swing doors with built-in wardrobes. This is because it maximizes the space that you have in your room. They are also tougher and less prone to damage and accidents. There are several types of sliding doors that you can install on your built-in wardrobe:
Many of people have sliding doors that open up to patios or backyards. These doors are an important part of our homes. They have aluminum tracks that let the door slide open and close. Over time, the aluminum tracks breakdown and the sliding door get stuck. The tracks are made from aluminum, which can become pitted and breakdown over time. Aluminum is a softer metal that it widely used because it is light weight, less expensive and adaptable. The manufacturers coat the aluminum tracks to protect them from corrosion and wear. However, over time the coating is worn off from continually opening and closing,which exposes the track to pitting and breakdown. Slider doors are frequently used, especially in summer month. With traffic going in and out of the house your sliding door can accumulate small stones, dirt and debris can get trapped in track and cause it to wear down over time. Moisture from weather conditions, such as snow, dew and rain can accumulate in the track and cause corrosion. Once these things happen the doors do not slide as easily and opening and closing making it a challenge.
There may be a few technical differences but logically they work the same, sometimes called a patio door when they open to the outside. 8. Bypass - the same as mirror bypass doors, without the reflective bits. 9. Louvered or shuttered doors are commonly installed for use with storage closets, utility rooms and pantries. They usually have two that bend inward when you open them, like a cats hind leg, and have the look of functional shutters. 10. Pocket - These bedroom sliding doors are used mostly for spaces that wont fit a hinged door. These slide into the interior of the wall and are sometimes difficult to pull back out if you dont know how to work the little flap of metal that makes up the handle.
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