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SOURCE: Merchant Warehouse
November 05, 2012 09:00 ET
Delivers Seamless Traditional and Mobile Payment Acceptance With Mobile Commerce, Featuring LevelUp
Delivers Seamless Traditional and Mobile Payment Acceptance With Mobile Commerce, Featuring LevelUp
BOSTON, MA--(Marketwire - Nov 5, 2012) - Merchant Warehouse, a leader and innovator in payment and program acceptance solutions and merchant account services, announces the general availability of Genius TX, a payment acceptance and mobile commerce solution that offers merchants a simple entry point into mobile payments.
In addition to providing acceptance of traditional payment types, Genius TX also supplies businesses with the ability to accept mobile payments, activate loyalty campaigns, engage in mobile-based co-marketing efforts and even provide a customized mobile payment application through the seamless integration with LevelUp, the Interchange Zero™ mobile payment and commerce solution. Genius TX is a stand-alone acceptance solution, designed specifically for merchants not using a point-of-sale (POS) system. Businesses using Genius TX also benefit from unified, web-based reporting, 24/7/365 in-house customer service and technical support, and a full suite of merchant services.
"We recognize the intrinsic value delivered to businesses through a payment solution that not only offers traditional credit and debit acceptance and mobile payment acceptance, but also features integrated mobile commerce and advertising opportunities," said Henry Helgeson, CEO, Merchant Warehouse. "Genius TX is engineered for merchants who are interested in expanding their value proposition through mobile payment acceptance, and it also offers incremental opportunity for business growth through integrated loyalty and advertising."
"LevelUp has always believed that for merchants, accepting payments and driving business growth should go hand-in-hand," said Seth Priebatsch, chief ninja at LevelUp. "Genius TX is a perfect product extension for us, since baking LevelUp right into the traditional payment acceptance is a dead-simple way for merchants to find real value beyond just moving money."
For more information about Genius TX, please visit http://merchantwarehouse.com/genius-product-family.
About Merchant Warehouse
Merchant Warehouse is a recognized leader in payment and program acceptance solutions and merchant services. The company enables merchants, agents, POS developers and VARs to achieve strategic business advantage through the delivery of current and emerging payment, offer and program solutions and merchant services that dramatically enhance the merchant-customer experience. Merchant Warehouse is one of the fastest growing innovators of payment solutions in North America. For more information about Merchant Warehouse, please visit merchantwarehouse.com.
For More Information on Merchant WarehouseSHIFT Communications
Mike Fearon
617.779.1807Email Contact
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Watch how to make this recipe.
Melt both chocolates and the milk in a double boiler over low heat. Remove from the heat and add in the corn syrup, chocolate-flavored liqueur and vanilla extract. Mix together and allow to cool completely.
With an electric mixer on high speed, beat the meringue powder with 6 tablespoons water in a medium bowl until glossy peaks form, 2 to 3 minutes. With a rubber spatula, gently fold the beaten meringue and the whipped topping into the cooled chocolate mixture until no streaks of white remain. Spoon into the prepared crust and spread evenly. Cover with plastic wrap and freeze until frozen, for a couple of hours. Garnish with grated chocolate and serve.
Meringue powder can be found now at most higher-end grocery stores or at craft stores in the cake decorating supplies section.

subset: commoncrawl


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Israel News - Stay Informed, Pray Informed
As the weather gets warmer, seeds are being planted for a new round of social unrest, reminiscent of the mass protests last summer over the high cost of living. With real estate, gas, food and electricity costs soaring, the people in Zion are unhappy.
"Netanyahu is starting to sweat," a member of the ruling Likud party told Israel Today. "He must get a hold on the cost of living or people will take to the streets."
In particular, Israelis are frustrated over the price of gasoline, which is heavily taxed by the government.
"The price of gas is going crazy!" an angry taxi driver shouted on Israel Radio. "We're not living in Europe here. The average Israeli earns 7,500 shekels [about $2,000] a month."
Interestingly, while the world is focused on Israeli threats to attack Iran, Israelis seem more concerned about how they are going to have enough money to finish the month.
To read more about Israelis' economic challenges, check out the May issue of our Digital Edition >>
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Powered by DulwichJazzBand.co.uk
The 'altered' 7th is a dominant 7th chord with an 'altered' (i.e. flattened or sharpened) 5 and 9: 1-3-b5(or #5)-b7-b9(or #9)
It is used as an alternative to a normal 7 chord, especially when the chord is due to resolve to a minor chord afterwards.
Standard scale choice
The 'altered' scale is also called 'super locrian' by rock types, while jazz players like to call it the 'diminished-whole-tone' because the first half is from a diminished scale, and the second half from a whole-tone scale: 1 b2 #2 3 b5 #5 b7
Hip options
There are lots of cool-sounding arpeggios contained in this scale which can make some hip sounds. For example, you could try alternating the major triad built on the root with the major triad built on the b5.
Another common trick is to play m(Maj7) arpeggios built on the note a semitone above the root. Art Pepper liked to do this.
If pentatonics are your thing, you could also try playing the "altered pentatonic" over this. That's the minor pentatonic based a semitone about the root of the chord, but with the fifth note of the the pentatonic raised by a semitone to function as the chord's root.


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Topic: Beauty And The Beast
Deadline for the voting: Friday, 16th June 2006
Posting thread (closed):
artist: Neorepto
concept: Seraph Whales and Angel's Tears
Planet Cautha is hostile to human life. A dense, rank, humid atmosphere of ammonia and sulfuric gas blankets the surface with a swirling, yellow cloud. Pressures and temperatures well exceed human tolerance. Nevertheless, the heavy metals mining is too good for human settlers to ignore the potential for profit. They've constructed domed colonies and scratch out an existence as best they can.
Seraph whales, one of the planet's few indigenous life forms, thrive in the skys above Cautha. There they live, perpetually swimming through the thick vapor, feeding on the microscopic young of Cautha's other thriving native life form, a silicon based mollusk referred to as "Angel's Tears." Angel's Tears have some things in common with Earth's aquatic barnacles. They are born as microscopic aeropods (a). Mixing with the airborne plankton, they become the primary food source for the seraph whales. Those that survive this larval stage mature (b) and cement themselves to the skin of the whales' head and jaw (c). Once attached, the mollusks form a rock hard protective shell, and breed, spawning millions of aeropods each.
When the Angel's Tears die, the cemented bond loosens from the seraph whales head and the tough shell falls to the planet surface. Human colonists avidly collect the shells much as one would collect seashells on a beach as souvenirs. The silicon crystaline shells are easily polished and carved into a variety of forms. Angel's Tears most often form six-sided shells, though occasionally seven-sided shells are found (d). Whether polished and carved, or left in the rough, their natural beauty is displayed as a native keepsake and a lucky charm in the colonist's home.
artist: MasumiX
the Beast is the large fellow, a land mollusk, he's a male, the colourful female is his lifelong partner, when not out foraging for copper and alum laden sands she spends her time latched to hsi under side, where her brightly coloured shell is hidden from predators.
artist: Might5cent
The Trakartan Tusked Lizards. As juveniles, both genders have long, thin spine protrusions connected with skin membranes, allowing them to glide short distances. The males grow thicker and heavier as they age, and eventually can no longer use the membranes for gliding. They are extremely aggressive, and protective of their territory. Violent fights and lack of use eventually tears away the membranes connecting their spikes. The females, who remain thinner and lighter, grow larger, colorful membranes, and remain able to glide throughout their lives, using the ability to escape danger.
artist: newmanhyde
The "beast" looks like a rat , hands of a mole , feeds like a frog and attract its prey like a flower. Every now and then the "flower" will produce too much poison and will cause pain to the beast.During that period the beast will cry out to attract the "beauty", cause only the "beauty" can feed on the poison and relieve the beast. So its a common sight to see the beauty near the beast.
artist: Tom Garden
The beauty wanders the forests, weaving in and out of the trees with its slender body. It has hightened senseory recepticals on its nose, which allow it to track the scent of its mate.
The forest the habitat is huge, and the beauties dont live very long. They desperately run rampant through the forest in search for a mate. The beast sadly is not of the same species, and nor can it mate with a beauty. But it lusts for the beauty, and has learned to reproduce the scent of the beauties mate. When beauties come across the colossal beast, they often stare in amazement and confusion. The beast advances with its bold romantic thoughts, and sadly - through its best efforts - kills the poor beauty. The beasts eerie moans can be heard for miles, as it mourns for what it has done.
artist: Goertz
concept: Kar'aal & Sidyiick
In the daytime on the planet Aurooba, the Kar'aal are often found searching for carcasses on wich to feed, if not allready lucky, stomping, teering and biting with foots, claws and beek in some unfortunate dead animal. This is often a dirty affair, wich typically ends up with a larger part of the Kar'aal covered in the insides of the carcass on whom it´s feasting, resulting in two things: first, the smell of the flesh and blood attracts other Kar'aal´s attention, wich often leads to dreadfull fighting and secondly it attracts all sorts of insects and parasites wich feast on both the remains and the Kar'aal itself.. Parasites like the protection its black backplates provide, from the ultra violet radiation coming from the star midas.
Besides protecting the Kar'aal when fighting, the backplates also stores heat to the coldblooded creature, beeing non-reflective; the perfect dwelling place for a large amount of Aurooba´s many species of parasites.
That´s also perfect for the Sidyiick, being an eater of basically anything wich can come through its tiny oral opening. When a Sidyiick finds a Kar'aal that has´nt got any Sidyiick "living" on it allready, it will stick by it, cleaning the large scavenger for small unwelcome guests and chase any other aproaching Sidyiick´s off.
artist: redehlert
artist: JakkaS
concept: Glishuk and Coreillo
Glishuks are huge creatures that inhabit the dark side of the moon called Kol. Because they live in a total darkness, their appearance is not so important. As opposed to other alike monsters, they didn't evolve such specific senses like smell, infravision, telepathy or even bioluminescence. However, Glishuks survived because they are big, have hard skin and they are omnivorous. Amount of food they have to eat every day forced them to live in dispersal. In the darkness it is almost impossible to find a good source of food. But to meet adequate partner to procreation is even harder. In a period of mating, instead of eating they collect Coreillos, small glowing snails. These little creatures are very poisonous, but their beauty affects everyone. Their shape reminds of bright flowers. Glishuks keep them in crops made of thin skin, so thanks to that, big monsters start to glow with all the colors of the small creatures. Yellow and Pink lights lure the females. After the mating period, usually up to one week, Glishuks release their dangerous cargo. Most interesting is that the scientists discovered, that the number of Coreillos is a little higher than from the beginning. Probably those snails multiply themselves in Glishuks' crops.
artist: kyi_72
this parasitic nudibranch forms a symbiotic relationship with its host. beginning as a spiny egg that imbeds itself into the lining of the mouth, it follows the bloodstream further into the head where it moves into the brain and central nervous system. gathering nutrients from the host it grows to enormous size, reaching maturity at 2 months, it sprouts apendages that extend out of the nostrils and move onto the top of the host as well as through the skin along the spine. these apendages relay information to the host, giving it a heightened sense of awareness. the host suffers no ill affects from the parasite, and continues its life as normal.
the 'flowers' at the top draw oxygen and moisture from the air, supplying the host with oxygen and using the moisture to produce a mucous that covers the nudibranch and deters predators, who find the smell repulsive.
artist: MIKECORRIERO
concept: Infested Wallow and the Carnivorous Ticona Plant
The Infested Wallow is used as a living food source for a carnivorous plant known as the Ticona which in the spore stage floats around and then burrows inside the Wallows skin sucking its blood much like a leech. When the Ticona has had its fill it falls off or burst out of the skin and will then dig its roots into the ground. This is where the Ticona goes into a type of metamorphosis and blooms into a spectacle of beautiful light and color.. unknowingly it also provides a food source for the Wallow which happens to love the taste of the warm blooded flora. Though the process is painful for the Wallow it is supplied with a free meal so it is content with the plant feasting on its blood supply. Various stages of the Ticona Process and an Infested Wallow are shown. The plants are careful not to kill their host because without this breed of animal the Ticona might become extinct if another host was not as accommodating.
artist: Bruce Jensen
concept: Hormsque
Hormsque are native to a small icy planetoid covered with ices of nitrogen, and smaller amounts of methane, ethane and carbon monoxide. The surface temperature varies between about -235 and -210 C.
A significant , though unmeasurable portion of the female Hormsque resides in 4th dimensional space tapping into the ambient energy for survival. The female is essentially intangible to the male, existing as shifting swirls of mist, and light. The male of the species thrives on the primordial organic matter, found locally. It's ability to draw on 4th dimensional zero-point energy is minimal, and unlike the female is essentially a creature of conventional 3-dimensional space.
Hormsque eggs are passed into conventional space by ovipositer, into a crater that is often reused by nesting pairs. The male fertilizes, and tends to the eggs. Hormsque eggs represent a significant potential food source, and are fiercely protected by the males against all attack. The hatchlings live a brief time in larval form before differentiating into either male or female of the species.
artist: Plate
concept: Aequidens Ducanthis - AKA the Gorgonfish and Neon Notchfin
For centuries, the male and female of this species were thought to be two entirely different types of fish; it was not until after recent study of one of the reefs they inhabit that they were revealed to be the opposite gender of the same species. While the two seem to have no regular direct interaction with each other, it has been proven that notchfins do in fact fertilize the egg clusters laid by the much larger and fiecer gorgonfishes. The current theory is that the two genders were once nearly identical, but took opposite routes when adapting to survival in their environment - the males have become sleek and agile, with colorful markings that camouflage them among the bright coral reefs they live in; conversely, the females have become large and ferocious, presumably in order to better defend their eggs and hatchlings. Upon hatching their offspring are white and nearly featureless - it is not until a week after birth that they begin to develop the features that identify their gender. Neon notchfins have become popular as pets in recent years, and are especially prized among collectors of exotic fish. Gorgonfishes, on the other hand, are generally avoided as much as possible.


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Dare to Dream
14, 16 & 18 May 2019
The Eurovision Song Contest is celebrating it's 60th birthday this year. The BBC hosted a celebration show to honour the 60th anniversary of the Eurovision Song Contest. Anne-Marie David performed Tu Te Reconnaîtras
Subscribe to the official Eurovision Song Contest YouTube channel for music videos, live show footage, exclusive behind-the-scenes material and our weekly updates.


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Trial of Donor T Cells Sensitized With Pentadecapeptides of the CMV-PP65 Protein for the Treatment of Cytomegalovirus (CMV) Infections Following Allogeneic Hematopoietic Stem Cell Transplants
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00674648
Recruitment Status : Completed
First Posted : May 8, 2008
Last Update Posted : March 1, 2017
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to test the safety of a transfusion of specialized white cells from your transplant donor's blood, called T-cells, that have been grown and immunized against the CMV virus in the test tube. If the transplant donor is immune to CMV (ie: the donor has antibody to CMV in the blood), the T-cells will be selected and grown from the blood of the transplant donor. However, if the transplant donor is not immune to CMV, or if T-cells from the donor are not readily available, CMV-immune T-cells grown from the blood of another normal donor who is partially matched to the patients tissue type can be used. The transplant physician will explain which of these treatments is available to the patient.
This trial is called a phase I trial because phase I trials are designed to test the safety of different doses of an experimental treatment. We want to find out what effects, good and/or bad, a dose/doses of these immune T-cells will have on the patient and on the CMV infection.
Specifically, we wish to test CMV immune T-cells grown from your blood using a new method developed at our center. In this method, fragments of an important CMV protein, called CMVpp65, are chemically synthesized and then used to immunize T-cells in the test tube.
|Condition or disease
|Cytomegalovirus Infections
|Biological: CMV-Peptide-Specific T cells
|Phase 1
Expanded Access : An investigational treatment associated with this study is no longer available outside the clinical trial. More info ...
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|30 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase I Dose Escalation Trial of Donor T Cells Sensitized With Pentadecapeptides of the CMV-PP65 Protein for the Treatment of CMV Infections Following Allogeneic Hematopoietic Stem Cell Transplants
|Actual Study Start Date :
|August 2007
|Actual Primary Completion Date :
|March 2014
|Actual Study Completion Date :
|March 2014
Experimental: 1
This is a non-randomized single institution phase I dose escalation trial, designed to evaluate the toxicity and anti-viral activity of CMV-pp65 peptide-specific T cell lines, generated in vitro from CMV seropositive normal HSCT and 3rd party donors, when adoptively transferred to treat recipients of these transplants who have a CMV infection or persistent CMV antigenemia and are therefore at high risk of a life-threatening CMV infection.
Biological: CMV-Peptide-Specific T cells
In this phase I trial, five escalating dose levels will be tested. Each dose will be administered to groups of at least 3 and up to 6 patients. Dose escalation will be based on the dose limiting toxicity (DLT) observed in each treatment group (Confer Biostatistics).
The patient groups and donors are outlined as follows: Group I will receive a single dose of 5 x 105 T cells/kg body weight/dose; Group II will receive a single dose of 1 x 106 T cells/kg/dose; and group III will receive a single dose of 2 x 106 T cells/kg/dose; group IV will receive 3 weekly doses of 1 x 106 T cells/kg/dose; group V will receive 3 weekly doses of 2 x 106 T cells/kg/dose.
- To assess the safety or toxicities of escalating doses of donor-derived CMV-pp65 peptide-specific T cells. [ Time Frame: conclusion of the study ]
- To quantitate alterations in the level of CMV antigenemia in the blood of patients with either active infection or persistent antigenemia following adoptive transfer of CMV-pp65 peptide-specific T cells. [ Time Frame: conclusion of the study ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|Child, Adult, Older Adult
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
Prior to receiving treatment, some patients may undergo diagnostic and/or other testing of their tissue, if available, to determine if their CMV infected cells are likely to respond to treatment with CMV specific T cells. Alternatively, blood samples may be required for research tests to ascertain that the CMV-specific T-cells do not contain any cells that could react against the patient. These patients will sign a separate pre-treatment consent. If it is determined that a patient will qualify for and might benefit from infusions of CMV CTLs, he/she will go on to sign the standard treatment consent for MSKCC IRB # 05-065 and be enrolled and treated on trial, if all other eligibility criteria are met.
- Each patient must satisfy at least one of the following criteria:
- The patient must have a clinically documented condition associated with CMV (e.g. interstitial pneumonia, hepatitis, retinitis) or
- The patient must have microbiological evidence of CMV viremia or tissue invasion as attested by viral culture, or detection of CMV antigenemia or detection of levels of CMV DNA in blood or body fluids consistent with CMV infection.
- The patient's CMV infection is clinically progressing or CMV viremia is persistent or increasing (as evidenced by quantitation of CMV antigenemia or CMV DNA in the blood) despite two weeks induction therapy with antiviral drugs.
- The patient has developed CMV viremia as attested by viral culture, or detection of CMV antigenemia or detection of levels of CMV DNA in blood or body fluids while receiving prophylactic doses of antiviral drugs to prevent CMV infection post transplant. or
- the patient is unable to sustain treatment with antiviral drugs due to drug associated toxicities (e.g. myelosuppression [ANC < 1000 ul/ml without GCSF support] or nephrotoxicity [corrected creatinine clearance < than or equal to 60ml/min/1.73m2 or creatinine >2 mg/dl]).
- Because CMV infections are life-threatening and may involve the lungs, liver, gastrointestinal tract, hematopoietic and central nervous systems, and antiviral drugs may also compromise renal and hematopoietic function, dysfunctions of these organs will not affect eligibility for this protocol.
However, to be eligible, the patients should meet the following clinical criteria:
- They must have a stable blood pressure and circulation, not requiring pressor support.
- They should have adequate cardiac function as demonstrated by EKG and/or by echocardiographic evidence.
- They should have a life expectancy, even if they require respirator support, of at least 3 weeks.
- They are no age restrictions to eligibility for this protocol.
Exclusion Criteria:
- Patients requiring high doses of glucocorticosteroids (>0.5 mg/kg prednisone or its equivalent) as treatment for active (grade 2-4) acute graft vs. host disease (GVHD) or chronic GVHD.
- Patients who are moribund.
- Patients with other conditions not related to CMV infection (e.g. uncontrolled bacterial sepsis or invasive fungal infection) which are also life-threatening and which would preclude evaluation of the effects of a T cell infusion.
Donor Eligibility for Donation of Blood Lymphocytes for Generation of
Donor-Derived CMV-Specific T cells:
Adequate health for donation as determined by institutional (related donor) or NMDP (unrelated donor) guidelines. Normal donors will be evaluated for evidence of prior sensitization to CMV by CMV serology. They will also be typed for HLA A, B, C and DR. For allogeneic hematopoietic progenitor cell transplant (HSCT) recipients, the marrow transplant donor will constitute the donor of choice, since those T-cells will grow and persist in a patient who has already engrafted with a transplant from that donor. However, if the HSCT donor is CMV seronegative or not available (e.g. a cord blood transplant or an unrelated donor who has not already donated T-cells for adoptive therapy), CMV-specific T-cells generated from a seropositive donor matched for at least 2 HLA alleles shared by the patient may be used.
Normal donors fulfilling these criteria who consent to donate blood for the generation of CMV-specific T-cells for adoptive therapeutic purposes will receive a detailed clinical evaluation, including a medical history, physical examination, and serologic testing for transmissible diseases within 1 week of donation including hepBs Ag and hepatitis C antibody, HIV-1 and 2, HTLV-1 and 2, CMV (only if previously negative), VDRL, WNV, and Chagas An HIV+ donor will be rejected on medical grounds. Donors must have Hgb value > 10 gm/dl and must be capable of undergoing a single 3-6 unit leukapheresis (preferable) or a single unit of blood for T cells (for pediatric donors, no more than 5 ml/kg at any one blood draw).
A prospective donor will be informed of the purposes of this study, and its requirements. If he/she consents, the donor will be requested to provide two blood samples:
i. An initial donation of 25ml blood anticoagulated with heparin or ACD. This blood is used to establish a B cell line transformed with the B95.8 laboratory strain of EBV. This EBV+ B cell line/ (EBVBLCL) will be used as an antigen-presenting cell. When loaded with the pool of CMVpp65 pentadecapeptides, the EBVBLCL efficiently sensitize T cells from the same donors against CMV as well as EBV.
Because the establishment and testing of an EBV transformed B cell line suitable for use or as an antigen-presenting cell require 4-5 weeks of in vitro culture, it is important that this sample be obtained as early as possible for patients at risk for a CMV infection. Because patients receiving HSCT from unrelated or HLA disparate donors are particularly at risk for severe CMV infections in the first 2-3 months after transplant, this blood sample should be obtained from the donor prior to donation of the hematopoietic progenitor cell transplant whenever possible.
ii. A donation of either a single standard 2 blood volume leukapheresis collected in standard ACD anticoagulant. If it is impossible to collect a leukapheresis from some of the donors, a unit of whole blood will be acceptable. However, the AICTF (Adoptive Immune Cell Therapy Facility manufacturing the clinical grade cell products under GMP conditions in MSKCC) may only be able to generate a limited number of T cells from a unit of blood. This blood is required for isolation of the T cells to be sensitized with the pool of CMVpp65 15-mers loaded on the autologous EBVBLCL, and propagated in vitro. In addition, it is required to provide autologous feeder cells essential to sustain T-cell growth without the risk of stimulating the growth of alloreactive T-cells capable of inducing GVHD.
This donation of a leukapheresis or a unit of blood will be obtained from unrelated HSCT donors at least 2 weeks after their donation of an HSCT, or as soon as possible thereafter.
In order to limit the number of blood or leukapheresis donations that would be required of any donor, each donor will be informed of the following potential applications of the blood cells donated. The white cells contained in one leukapheresis are sufficient to grow enough T- cells to treat the three conditions below in a transplant patient:
- The use of cells to generate CMV-specific T-cells for potential use in the treatment of the patient for whom the donor has provided an HSCT, under MSKCC IRB # 05-065.
The use of a fraction of the cells isolated to generate:
- immune T-cells specific for another virus, such as Epstein-Barr virus, that can cause lethal lymphomas in transplant recipients, and
- immune T-cells specific for a protein called WT-1, that is differentially expressed by malignant blood cells.
Such T-cells could be used, under separate protocols, to treat EBV associated diseases (IRB 95-024) and/or to treat or prevent leukemia recurrence (07-055) in the patient receiving the donor's hematopoietic progenitor cell transplant.
- The donation of the immune T-cells generated from the donor that are not used for or required by the patient for whom they were originally intended to a bank of immune cells that will be stored and maintained cryopreserved under GMP conditions in the Adoptive Immune Cell Therapy Facility at MSKCC, These stored T-cells , may be used for the treatment of other patients with CMV or EBV infections/malignancies that express HLA alleles shared by the donor.
In addition to these prospectively accrued donors, we have, since the initiation of this protocol, generated over 100 CMV-specific T-cells for patients at high risk for infection, of which far fewer patients have required treatment. Since these patients are now beyond the period of risk for CMV infection, their donors will be approached with a separate consent to allow for the use of their T cells in recipients other than the primary patients for whom they initially donated cells.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00674648
|United States, New York
|Memorial Sloan Kettering Cancer Center
|New York, New York, United States, 10065
|Principal Investigator:
|Susan Prockop, MD
|Memorial Sloan Kettering Cancer Center
Additional Information:
|Responsible Party:
|Atara Biotherapeutics
|ClinicalTrials.gov Identifier:
|NCT00674648 History of Changes
|Other Study ID Numbers:
|First Posted:
|May 8, 2008 Key Record Dates
|Last Update Posted:
|March 1, 2017
|Last Verified:
|February 2017
Keywords provided by Atara Biotherapeutics:
Multiple Diseases
Hematopoietic System
Additional relevant MeSH terms:
Communicable Diseases
Cytomegalovirus Infections
Herpesviridae Infections
DNA Virus Infections
Virus Diseases


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Subscribe To Waiting To Exhale Stars And Writer On Whitney Houston's Death And Status Of The Sequel Updates
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From what I've heard, in the wake of Whitney Houston's unfortunate passing, it seems like comments regarding the singer's film career largely lead to discussion of The Bodyguard. When I think of Whitney and The Bodyguard, my mind goes straight to the outstanding soundtrack. When I think of Whitney and film, Waiting to Exhale is what comes to mind. The Forest Whitaker directed movie is on the list of film I have to watch if I find it on television, not matter what part it's at when I come across it.
Houston starred alongside Angela Bassett, Loretta Devine, and Lela Rochon in this film adaptation of Terry McMillan's novel about four African American women struggling with romantic issues while finding friendship in each other. Despite having seen it many times, I always have to watch to see Bernadine's amazing meltdown and comeback, Gloria's attempts to connect with her son, Robin's efforts to find a decent man who treats her right, and Savannah's relationship with a married man. I'd say Houston held her own in her performance as Savannah, especially when factoring in the amount of talent among the cast of the movie.
Following Waiting to Exhale, Houston went on to appear in two other films in the later part of the '90's. And coming soon, those who were hoping to see her return to the big screen will get their wish when Sparkle releases in theaters this August. What might have been her big comeback to acting will unfortunately be her final role.
MTV posted some comments shared by Waiting to Exhale writer Terry McMillan and some of the cast of the film, which includes a couple of references to a sequel that may have been in the works, based on McMillan's follow-up novel Getting to Happy.
Part of Angela Bassett's statement says, "I am so thankful to have been enveloped by the warmth of Whitney's great talents. They were undeniable and vast." And among numerous tweets on the subject of Houston's passing, McMillan said:
I am not thinking about the damn movie. So please, don't ask.
Meanwhile, from what Loretta Devine said, Houston was excited to get going on the Waiting to Exhale sequel...
"I am overwhelmed. I cannot wrap my mind around this. I missed the chance to see her at a party this past Thursday and when we spoke last she had just finished 'Sparkle' and she told me how excited she was to start production on 'Waiting to Exhale 2' with Angela, Lela and myself."
At this point, it's probably too soon after Houston's death for any major discussions on the future of the project to be had. But it's hard to imagine the story without Savannah in it or to have the role recast. So we'll have to wait and see what transpires. In the meantime, our thoughts go out to Houston's friends and family.
For those Houston fans who have already exhausted themselves on listening to the star's greatest hits, Waiting to Exhale is available on Netflix Watch Instantly.


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Go There: Reunion Island
French Flair in the Indian Ocean
Where: The verdant west coast of Reunion, in the southwestern Indian Ocean. Reunion sits off the east coast of Africa, due east of Madagascar. For U.S. travelers, it's an incredibly long series of flights, but the mix of great surf and culture makes the payoff well worth it.
What: A volcanic dot of tropical French idyll, flavored with Creole, Indian, African, and Chinese culture, endowed with some of Earth's finest natural beauty.
When: April through July, when the Roaring Forties spawn oodles of swell, headed straight for Reunion's west coast. Instead of wallowing in next summer's sloppy, crowded waves at home, you could be pulling into Reunion's turquoise tubes and whacking come-hither left-hand lips 'til the cows come home.
Why: Remember Occy ripping Saint Leu in those old Billabong videos? Or the recent footage of Jordy and crew in Modern Collective? Or the fact that the ASP has staged pro contests there? That's reason enough to hop halfway around the planet, kids. Reunion's west coast blows straight offshore with the prevailing trade winds, and swell is almost guaranteed during peak season. Plus, the food's killer, the weather's perfect, and the scenery is virtually unparalleled.
How: South Africans need visas. Roland Garros International Airport (RUN) receives direct flights from Mauritius, Seychelles, Madagascar, South Africa, and France. April through July is Reunion's peak tourist season, but you'll save cash if you book a discount ticket to London or Paris, then a separate ticket to Reunion on Air France, Air Austral, Air Mauritius, Corsair, or Air Madagascar.
Places To Stay: St-Leu's three-star Paladien Apolonia is plush but a double room starts at $150 per night. Directly across the street from the wave is Dodo Spot; a double room there starts at $36 per night. They also offer cabins. The Campix campground is open March to November. For cheap deals, stay in guesthouses ($40/$60) slightly out of town or go to St-Pierre or St-Gilles. Otherwise, there are many other options, from five-star to one-star, self-catered to pampered, all relative to your budget.
Places To Eat: Pepto-Bismol is handy because although tasty, a lot of Reunion's food is très spicy. The French love food, of course, so almost any exotic dish you can think of is available, be it French, Indian, Asian, African—you get the idea. Don't leave without trying Creole rougail, a spicy chutney. You may want to pass on the octopus vindaloo and bat curry, though.
Bros And Babes: Plenty. The bros are mostly French for those of you ladies who have a fetish for all that is Francophilian. And who can scoff at nubile, topless French chicks swirling hot beach sand between their fingers at Boucan Canot? Or all those sultry lasses eyeing you on the dance floor in the Saint-Gilles disco? Yep, Reunion is holding!
Crowd Factor: Saint Leu gets packed, but there are several other quality reefbreaks along the west coast. Mind your manners, learn a few cool French phrases (bonjour ami! is a good one: "hello friend!"), wait your turn, and never, ever drop in on anybody. With a finite number of spots and a seemingly infinite number of surfers on one tiny island, there's bound to be some tension. Reunion is one of the world's top ten locations with the highest shark attack activity, and it has a bad record of attacks on surfers (a surfer was killed in 2006 and another recently attacked).
Stuff To Bring: Windchill often warrants a vest. Reef booties and shark repellent aren't bad choices, either. You can ride almost any board at Saint Leu, but you'll want something gunnier and pintail-ish for hollower, scarier spots like L'Hermitage and Pic du Diable. If the extent of your French is oui and bonjour, definitely pack a French phrasebook. Not only will it make life easier, it will greatly enhance your game with the local mademoiselles. Don't forget hiking boots, either (see below).
If The Surf Is Flat: You can bronze on the beach among hot, topless girls for starters. But if you're looking for a more athletic endeavor, then lace up your trail boots, because Reunion's interior is world-class, stacked with epic mountains, active volcanoes, and crazy ravines, all offering unreal scenery. At night, party hearty in Saint-Gilles. The capital city of Saint-Denis is also interesting, and you can't go wrong with a jaunt to Hell-Bourg, self-proclaimed as "one of France's most beautiful villages."
More Information: Reunion has no official tourism site, but if you speak French, there's loads of stuff online. Good info in English can be found at runweb.com, iledelareunion.net, lonelyplanet.com/destinations/africa/reunion/, reunionisland.net, and wannasurf.com/spot/Africa/Reunion.


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Over the coming days, I will be writing three new posts about my dessert experiences in New York City. This trip was planned as a birthday get-away for Mie, Teresa and myself (my birthday is still 4 months away). We have been friends ever since high school and their friendship means a lot to me. I would also like to thank Matt and Phillip for their friendship, hospitality and for always recommending new and wonderful places. I had a fantastic time in New York, sleeping-in, eating and most of all hang out with friends.
If you are interested in other places to go to in New York, check out my first five posts written in May, 2006.
post 1 : Jean George
post 2: Chickalious & Room 4 Dessert
post 3 : Cream Puffs in New York
post 4 : Bouchon, Fauchon, Minamoto Kitchoan, Wichcraft
post 5 : Chinatown Ice Cream Factory, Rice to Riches, Fluff
Serendipity 3:
Serendipity: to make discoveries, by accident and sagacity, of things not in quest of.
I first saw the film Serendipity in 2002, the summer I came back from grad school in London, I never heard of it while I was England. For all those who haven't seen it, it is a romantic comedy starring John Cusack and Kate Beckinsale where they fall in love by chance. My sister made me watch it. Anyhow, there is a scene where they meet up at a restaurant in New York named Serendipity.
Serendipity 3 is a fun and accessible restaurant, which brings up memories of comfort food and childhood favourites such as hot fudge sundaes. I'm not sure whether it was the movie or their reputation, but this restaurant can be difficult to get into. On two other visits to New York, I had planned on eating there, but the lines to get in were unmanageable. On this trip however, my friends and I were able to get in within 10 minutes of waiting in line. Once we were in, we ordered the "coward's portion" of the banana split as we didn't think we could eat the ridiculous amount of ice cream in the "outrageous banana split" and the "big apple" pie. The frozen hot chocolate, I have been told is the drink to get. All their ice cream creations are made with Häagen Dazs.
The reason why I think this restaurant does well, is that it plays on our sense of nostalgia. Our dessert at Serendipity was simple and enjoyable. However desserts like sundaes and banana splits are things that I rarely indulge in. I would recommend Serendipity 3 if you were looking for comfort food, desserts or a bit of nostalgia, otherwise don't bother braving the line.
Serendipity 3
225 E. 60th St. (between Second and Third Ave)
New York
212 838 3531
Technorati Tags: Dessert, New York, New York Restaurants


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Behind the Scenes: Intern Q&A with Jihaeng
June 11, 2013 in Appaman News, NYC
Have you ever wondered what it's like to intern at Appaman HQ? We sat down with Jihaeng, a very talented young lady who was gracious enough to spend this past semester as we developed the Spring/Summer 2014 collection. Read on to find out what she worked on during her Appaman internship, her advice for students going into fashion design, plus her tips on personal style…
Jihaeng Lee, Design Intern
School: Fashion Institute of Technology (FIT) – graduated May 2013
Major: Fashion Design with a specialization in Childrenswear
From: South Korea
Previous Experience: Internships at Khan Lucas and Rebecca Minkoff
(click through to read the full Q & A)


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TeX Live 2018 was released on April 28.
For typical needs, we recommend starting the TeX Live installation by downloading install-tl-windows.exe for Windows (15mb), or install-tl-unx.tar.gz (3mb) for everything else. There is also a zip archive install-tl.zip (19mb) which is the same as the .exe. Although the .zip archive works fine on all platforms, the .tar.gz is much smaller, since it omits installation support programs needed only on Windows. The archives are otherwise identical.
The above links use the generic mirror.ctan.org url which autoredirects to a CTAN mirror that should be reasonably nearby and reasonably up to date. However, perfect synchronization is not possible; if you have troubles following the links, your best bet is to choose explicitly from the list of CTAN mirrors (you'll need to append systems/texlive/tlnet to the top-level mirror urls given there to get to the TL area).
After unpacking the archive, change to the resulting install-tl-* subdirectory. Then follow the quick installation instructions or read the documentation.
If you need to download through proxies, use a ~/.wgetrc file or environment variables with the proxy settings for wget. TeX Live always uses GNU wget to download.
With this network-based installation method, what gets installed is the currently available versions of packages and programs. This is in contrast with the other installation methods, which are kept stable between public releases.
Sources: the live network installation does not include the hundreds of megabytes of sources for the compiled programs. The sources for the current release are on CTAN, and historical releases are also available, and of course current development sources are in the repository.
Information about downloading/mirroring the TeX Live archive repository is available separately, as well as other ways to acquire TeX Live.


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ShopHomeo.com™ is operated by Jhactions® Homeopathy Store, A sister concern of Jhactions Homoeo. Jhactions® Homoeo has a long tradition of more than 20 years in manufacturing of quality homeopathy products.
© 1993-2017 Jhactions®. All product names, logos, and brands are property of their respective owners. All company, product and service names used in this website are for identification purposes only. Use of these names, logos, and brands does not imply endorsement.


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We've been down this road just recently with a few in-state players — UM's Deshawn Sims and Manny Harris come to mind, along with Oakland's Keith Benson. It's the big question on everyone's mind: Are they good enough for the NBA.
In Harris' case the answer is a hearty "not yet," while in Sims' case it's a definitive "not a chance in heaven or hell."
Benson: Yessir.
But what about MSU's Draymond Green? The undersized power forward from Saginaw High has been among Michigan State's best and most consistent performers this season — not to mention easily the Spartans' top post threat.
In a recent blog about Green's NBA chances, Mlive's Patrick Hayes (a friend and NBA sage) puts forth his opinion that if Jason Maxiell can do it, why not Green?


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Ocean Galleries is a distinguished art gallery with locations in Stone Harbor and Avalon, New Jersey
Anytime you visit either location, you will see an ever-changing display of artwork that includes local artists' watercolors, nationally-recognized artists' originals, popular beach prints and high-end reproductions. We also carry fine furniture and hand-made crafts from around the world and are continuously updating our collection.
Click the links on the top of this page to explore our gallery, view custom framing solutions, learn about past and upcoming gallery events, and to read more about Ocean Galleries' history and locations.


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May 21, 2009
Ok, Inspired by the recent publicity of Farrah Fawcett's current cancer struggle. One doctor on CNN did say that people with HIV & HPV are at higher risk for anal cancer. I am a 35 year old HIV Positive gay male, Minor battle with anal warts at one time, Undetectable VIral Load on Atripla for 3 years now, CD 4 range 575-675 and 34%. When should I insist on anal cancer, colon cancer test due to my increased risk factor? Thank you so much for your informative, common sense and at times, funny responses to many important and light hearted questions! We all love you!
Response from Dr. Frascino
Hi Farrah Fawcett Fan,
Your HIV specialist should monitor you with anal pap smears on a yearly basis as well as with periodic visual inspection and digital rectal exams. Colonoscopy should be done at age 50; sooner if certain symptoms, such as bloody stools, occur.
Good luck.
Dr. Bob
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The light brigade
By Arnie Katz
Q: I've been seeing LED light bulbs in the stores lately. They claim they'll save a bunch of money, but will they really? Will they actually last as long as they say? I got burned by buying some CFLs a few years ago that didn't last very long, and I don't want to make the same mistake again.
A: These are excellent questions. Let's first talk about how long light bulbs will last. There's a standard procedure for how long manufacturers can claim their light bulb will last. Basically, they put a bunch of bulbs in sockets and turn them on, let them run for three hours, turn them off, turn them back on for three hours and continue to do that until half the bulbs have burned out. That point — where half the bulbs have burned out and half are still on — is called the average life of the bulbs. That means you can expect half of the bulbs to burn out quicker than that average life number and half to last longer. If you typically have the light on for less than three hours at a time, it will probably not last as long.
LEDs are tested a bit differently since they don't really "burn out." Instead, they get dimmer over time, and the "average life" is when they've dimmed to the point where most people will notice. Yes, that's a bit fuzzy.
The incandescent light bulb most of us grew up with was essentially unchanged for more than 100 years. The companies that made them had vast experience and learned how to have excellent quality control. As a result, these bulbs rarely fail prematurely, and most of the products last close to the average life on the label.
When new products are introduced, they bring new problems, and it often takes a while to work out the bugs in the system. Sometimes, this leads to less than ideal quality control and product failures.
CFLs are a classic example of this. The first ones I purchased in the 1980s cost $25 each. When I ran the numbers, the combination of much longer life and energy savings convinced me they were a good investment. Most of them lasted at least as long as promised and turned out to be a good value. (Yes, I know, thinking of light bulbs as an investment is a little strange.)
There were some, however, that failed early — very early. Most of those were much cheaper than the name brand bulbs. Clearly, I got what I paid for.
Over time, most CFLs have become very reliable. They last much longer than incandescent bulbs and use a quarter to a third as much electricity, making them a much better investment.
There are still some issues to consider. Does the bulb put out enough light? As I get older, I need more light just to see as well as I used to with less light. Brighter, higher wattage CFLs may do the trick, but you need to install one in your lamp or fixture to make sure.
Some folks have problems with the color of some CFLs. Again, buy one to test in your house and see how you feel about it. There are now a lot of different brands on the market, with different qualities. If you try one you don't like, try another brand. You no longer have to take out a loan to buy these things — they've gotten much more affordable in recent years.
LEDs are about where CFLs were a few years ago. We're just starting to see more products on the market. They're still quite expensive, but the prices are coming down. Almost all of the independent testing verifies they should last at least 25 times longer than the old incandescent and use much less electricity than even the CFLs. There are a lot of different products out there, so if you try one and you don't like it, try something else.
Now that we're well into the 21st century, maybe it's time to say thanks and farewell to Mr. Edison's 19th-century light bulb.


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Decision legislative initiative 'resale of admission tickets' now in hands of Dutch senate
On Tuesday April 6th, the legislative initiative 'resale of admission tickets' by Arda Gerkens (Socialist party) and Nicolien van Vroonhoven (Christian Democrats) was accepted by a majority in the Dutch parliament. This however does not mean that the law immediately takes effect – the Senate has yet to study the proposal. Not until the Senate has voted, does it become clear whether the law will actually take effect.
We will keep you informed of future developments.
The aim of the association, as an association of undertakings, is to guarantee the quality and professionalism of the entrepreneurship of secondary ticket sellers, and to protect the individual and collective interests of its members, and this applies in the broadest sense of the word.
The association will attempt to realise these goals by, amongst others:
– establishing rules of conduct and clear guidelines for market parties involved in secondary ticket sales;
– offering transparencies and guarantees to, and for the benefit of, the consumer with regard to bought and resold (admission) tickets for events, and increasing consumer trust in these purchases;
– establishing a trademark for the benefit of the consumer, which is adopted by market parties involved in secondary ticket sales;
– actively promoting the regulatory body for secondary ticket sales in the media, as well as providing general information;
– stimulating contact among members;
– organising meetings, lectures, talks and courses;
– co-operating in the creation of private law and public law bodies, with a view to becoming a member of these bodies;
– becoming actively involved in law suits for the benefit of the member collective;
– employing any legal means necessary.


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Print your Red Sox tickets from your computer after you make your purchase from redsox.com!
Purchase your tickets online and you can print your tickets immediately after you purchase them. Just select 'Print Tickets at Home' as your delivery option and your tickets will be e-mailed to you after you have completed your purchase. All you need is a printer and your tickets can be in your hands today!
Please note that only individual game tickets can be printed at home.
Here are some FAQ's which will hopefully help answer some of your questions, if you have any:


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6th Annual Fireside Chat with President David R. Hopkins
Tuesday, November 5, 2013, 7 pm to 8:30 pm
Hamilton Hall Lounge
Current Students
First Year students are invited to share a fireside meal with Wright State's freshest tweeter University President David Hopkins. Rise, Shine, and Serve is the theme this year. This is an event where first year students can hear from the University President in an informal setting, as well as ask him questions. There will be breakfast foods and a raffle for prizes.


text: The Christian Gamer is a believer in Jesus Christ as the way to eternal salvation (John 3:16). As a Christian, responsible to God for my actions and thoughts, I promise to choose my games carefully. My goal is to be a good witness in my purchasing decisions, in my game play with others, and in the use of my time.


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NEW HAVEN, Conn. - Yale's open four began the weekend slate of racing this morning for the Yale lightweight rowing team, finishing third in its heat. The crew, racing in a heavyweight event, is made up of Michael Buttrick, Chad Bailey, Joseph Hanlon, Drew Lawson, and coxswain Wendy Lin. By rule, it must include at least one freshman and at least one upperclassman among its oarsmen.
With only one crew to advance straight from the heat to the final, the Bulldogs went for the victory in this morning, leading early before being passed by Harvard and Brown. Yale finished with a time of 6:29.6, 5.4 seconds behind the Crimson and 1.6 seconds behind Bruno. The Bulldogs finished 3.5 seconds ahead of Cornell.
The open four will resume racing tomorrow with a repechage at 9:30 a.m. Yale will race in lane 4, and will be joined by Cal, Wisconsin, and Penn. In order to advance to Saturday's grand final, the Bulldogs must finish in the top two in their repechage. In addition to Harvard, Washington qualified for the grand final by winning their Thursday heat.
Yale's boats entered in the lightweight eight will weigh-in tomorrow at 3:00 p.m. and begin racing on Saturday.
Full race results can be found here. A live video stream of all events will resume Friday morning at 8:30 a.m. here, or here for those viewing on a web-enabled mobile device.
Report filed by Yale Sports Publicity


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Full name: Austin Smith
Birth date: December 14, 1988
Home: Bend, Oregon
Sponsors: Quiksilver, K2, DaKine, Airblaster, Side Effect Boardshop, Elm Company, Cobra Dogs, Volcano Cones
Results: I don't really do contests.
Film: We're People Too/MDPeople.
Who are your biggest influences?
1. My Brother.
2. Bryan Fox.
3. Curtis Cizek, Jake Price, Tyler Sharpf, and the diggers.
What do you want to get out of snowboarding?
Ten more years of living the dream.
What's your favorite video part?
Andrew Crawford in The Revival, Bryan Fox in Some Kind Of Life, or Lukas Huffman in Happy Hour.
Worst trend in snowboarding?
Multiple tricks on one rail.
One thing we don't know about you?
My truck runs on vegetable oil.
Three things you want to do before you die?
1. Be really smart.
2. Have some mini Austins.
3. Get barreled.
What is the sketchiest thing you've ever done on a chairlift?
Stood up maybe.
One trick you wish you could do?
Switch frontside 360s into powder.
One trick people should stop doing?
Back-to-back anything.
"Austin is a rarity in snowboarding these days. Not only is he incredibly talented and gracious, he's humble as well. I had the pleasure of introducing Austin to his first Whistler experience-the rain, Canadian firewater, hot blondes with big boobies, and late nights for weeks on end with no sun. He handled himself like a man, and while I was in the woods puking on the side of the run, he was doing cab 900s-and that's when I realized he was the golden boy. He comes from a small town and a humble upbringing, and I instantly knew he would go the distance. He's a wingman in every sense of the word, and I was proud to show him everything he shouldn't do on the road when it rains. He's so fun to shred with and reminds you of why you started snowboarding in the first place. Keep your eye on this one, he's the real deal!" -Andrew Crawford


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Our friend Pete Hegseth, founder of Vets For Freedom, is now posted to Afghanistan, where he is training Afghans as well as American and coalition troops. His reports on the situation there are as knowledgeable as any you can find. Here is his latest dispatch, hot off the press:
In counterinsurgency warfare, the population is the prize. The strategic sympathies of people in cities, villages, and the countryside are what both insurgents and counterinsurgents seek. Population support—whether active or passive—determines physical freedom of movement, either stifling insurgent operations (see my 2008 articles from Baghdad and Samarra) or providing safe haven and support (Marjah, 2009). The same goes for counterinsurgents.
The means of acquiring population "support" differs from battlefield to battlefield. Historically, more coercive tactics like forced relocation, food rationing, and corporal punishment were used to "convince" the population to support the government and counterinsurgents. Today, with such tactics frowned upon, counterinsurgents target the population's perceived self-interest (the oft-misunderstood "hearts and minds"), seeking to provide secure streets, effective governance, and economic opportunity. Of course, killing bad guys remains critical.
Such is the state of play for counterinsurgents in Afghanistan. The Government of Afghanistan, Afghan Security Forces, and our military forces use every (capable) asset available to garner population support; and the Taliban and other insurgent elements do the same. Lately, however, news reports from Afghanistan have made discerning battlefield trends difficult. Was the helicopter attack that took 30 American lives indicative of a desperate, weakened enemy? Or instead evidence of heightened insurgent sophistication? Is the reintroduction of U.S. troops into the critical Pech Valley in eastern Afghanistan evidence of an adaptive strategy? Or just another round of whack-a-mole? The answers are not immediately clear.
Likewise, recent media reports and official statements remain at odds. It seems that almost every press story talks of "deepened worries" and "escalating fears" amongst Afghans, especially after multiple assassinations and suicide bombings this summer. Some in the media would like us to believe (or at least paint the picture) that the hinges are close to coming off, and the prospects for success very low. On the other hand, our Commander, Marine Corps General John Allen recently emphasized that "all across Afghanistan, the insurgents are losing." I heard him speak a few days ago, and he is impressive. Smart, tough, savvy, and unrelenting—he started his speech by saying "make no doubt about it, we will prevail." Then, with a half-cocked smile, he reiterated that he has an open-door policy, and anyone who doesn't think we can prevail should make an office call. I'd follow this guy anywhere.
Internal military indicators support the general's near-term assessments, with attacks trending slightly downward this summer. However, at the same time, the number of IED attacks has hit all-time highs, with 1,600 strikes in June (we can thank Pakistani bomb-making materials). Again, is this evidence of a frightened enemy (IEDs require less tactical risk) or just a shift in strategy? All of this data is important, and helps paint the picture. But what really matters is how the Afghan people perceive their security and their future. It doesn't really matter if we reduce attacks by 10% or insurgents increase suicide bombings by 20%. Nor does the number of dollars spent, the number of Afghan soldiers trained, or even the number of U.S. casualties ultimately determine mission success. Sure, they matter to you and me. But, how do those numbers impact the perception of the Afghan people? That is the consequential mission metric.
Reality shapes perception, but only when continually reinforced and usually with a serious lag time. For example, despite substantial improvements in the numbers and capability of the Afghan Army, many Afghans still doubt their ability to provide security when we leave. Likewise, we are shipping them $2.7 billion worth of military equipment (22,000 vehicles, 44 airplanes and helicopters, and 40,000 weapons) in the next eight months, but will it translate into enduring security? Over time, either the reality of Afghan capability will take root in the public consciousness, thereby bolstering public support; or insurgents will continue to stoke public doubt and the people will never turn, en masse, to Afghan forces. In the meantime, the Army struggles to prove its newly gained acumen in the face of years of public uncertainty.
Ultimately, if Afghans believe that we—the counterinsurgents and Government of Afghanistan—are winning and most capable of providing a better future, they will side with us. And if they believe that the Taliban remains sufficiently potent and will eventually carry the day (or outlast us), then they will side with the Islamists. Ultimately the people will decide, based on their perception of the "top dog" (see my FoxNews.com clip). Of note, a grizzly Afghanistan veteran recently reminded me that "if the Afghan people really wanted us out, they could have risen up by now and made our lives hell." He's right, and that hasn't happened (like it did to the Soviets), demonstrating that most Afghans see our utility but are waiting to see if our dog (the Afghan Army & Police) will be able to defeat the rabid dog (the Taliban) that nobody wants to return, but still lurks in the shadows of the national sub-consciousness.
Our goal is not to be "loved" by Afghans; however, U.S. national security interests are tied to the perceptions of the local population—whether we like it or not. Our approach is not about "nation building" or "soft power" (even though it includes elements of both), it is a comprehensive civil-military approach aimed at achieving our strategic objectives (the denial of radical Islamist safe havens). As an aside, if we're serious about impacting national and local perception—and altering the trajectory of the war—we need to think creatively about how we conduct information operations inside Afghanistan. My idea: hire Karl Rove and James Carville, bring them to Kabul, and cut them loose. Our information operations and media engagement—especially at the national level—are slow and unresponsive, allowing the Taliban to shape the narrative of most events. Instead, we should treat this war as a campaign—how we portray our record, spin events, and project our plan impacts how Afghans perceive us, and whether they eventually "vote" for our side. Just one captain's crack-pot idea…
That said, at the Counterinsurgency Training Center—Afghanistan we teach the eight historical "principles" of counterinsurgency. Derived from history (largely the French in Algeria, the Brits in Malaya, and our war in Vietnam) these principles represent a basic list of what counterinsurgents should emphasize in order to be successful. While every campaign is different, and nothing is set in stone, most successful counterinsurgencies employ these principles effectively, while unsuccessful efforts do not. All things being equal, if counterinsurgents employ these eight, they will influence popular perceptions, capture the strategic sympathies of the population, and—in short—win. If they don't, it usually doesn't end well.
As General Allen reminded us, 2011 will be the apex of American influence and represents our best opportunity to degrade a "witch's brew of insurgency." So, in making sense of the trends in Afghanistan, I broke down the current state of each "principle." Admittedly, my assessment is geared toward our deficiencies, so please don't interpret this rundown as inherently pessimistic. Instead, I've tried to provide a realistic layout of what I've seen/heard/analyzed thus far. The results—while only one soldier's opinion and by no means exhaustive—provide a glimpse into our impact on the population. As with the last email update, it's lengthy; so grab a frosty beverage and proceed at your own risk.
The Principles of Counterinsurgency:
Legitimacy is the Main Objective. At the national level, with a full-fledged "constitutional crisis" recently averted (President Karzai finally dissolved his special election court), skepticism still remains about the functionality of parliament, the President, and the financial system. It doesn't help that his brother (along with the First Vice President's brother) was one of the largest benefactors of the "great Afghan bank heist," personally pocketing tens of millions of dollars from Kabul Bank before being absolved by a Karzai-appointed "commission." At the local level, urban and rural Afghans alike regularly pay sizable bribes to security forces and government officials, a staggering sum aggregated to 25% of Afghanistan's GDP. The Taliban uses this information shrewdly, claiming to "cleanse" Afghanistan of corrupt officials with every assassination. Endemic corruption at all levels remains public enemy number one, undermining public perception of the government's legitimacy.
Unity of Effort is Essential. With 48 nations contributing to the fight in Afghanistan—most saddled with "national caveats" that limit them to safe areas or "peacekeeping missions"—a unified effort is difficult to achieve. As a result the U.S. ends up carrying the load, while other countries do their best to contribute on the margins (some, like our Aussie and Brit friends, more than others). Such is the reality of "international counterinsurgency." That said, our own agencies also don't contribute equally. When the military "surged" earlier this year, we heard about a parallel "civilian surge" from the State Department. A well-informed friend calls this a "myth" and "a joke, if it weren't so serious." Many State Department folks do an excellent job, but across the board there still isn't the talent, experience, or sheer number needed to provide badly-needed local governance expertise. As a result, this job falls to the military—because, as one Army Colonel put it, "there is no inter-agency tooth fairy." The addition of Ryan Crocker (of Iraq fame) as the new U.S. Ambassador in Kabul will help in forging a "whole of government" approach, but there is still much work to be done.
Political Factors are Primary. Two paragraphs above, I mentioned legitimacy—which ties closely to political primacy. A perfect example: the Kabul Bank scandal. Not only did well-connected government officials make out with millions of dollars, but as a result of the capital loss, "the Afghan Ministry of Finance was given orders to increase tax collection in order to generate a portion of the $820 million needed to bailout Kabul bank [and] stay in good standing with the International Monetary Fund." The corruption is bad enough, but the second and third order effects—in this case through taxing an already struggling population—are even more detrimental. Another small aside: without continued donor funding at current levels, the Afghan government would literally face insolvency within one month (one month!).
Politically, the question we have failed to prioritize over the last decade of war is: does the local population believe that their government is going to outlast the enemy's alternative government structure, and ultimately provide services and security for the long term? And the more we view the Taliban as a terrorist organization—rather than a parallel government-in-exile—we will fail to address the political core of this conflict. To this end, internal polling in eastern Afghanistan (a key area) indicates that local Afghans believe [perceive] the Karzai Government will not last more than thirty days after we leave. Even more critically to the Afghan state, if the current political trajectory continues, the Afghan Army—no matter how large and how capable—may have no government left to defend. Security gains (especially in southern Afghanistan) can help create the necessary, but not yet the sufficient, conditions for the government to develop; but if it doesn't happen soon, the Taliban will continue to fill the void though 2014 and beyond.
Counterinsurgents Must Understand the Environment. U.S. and Afghan forces have made strides in this area, slowly widening our aperture beyond a purely enemy-focused, kinetic strategy, and towards a population-centric approach. (The Marines, God bless them, took this to the hilarious extreme, banning "audible farting" because it's offensive to Afghan civilians). Rather than spending 95% of our time on bad actors who constitute 5% of the population (think of that troublemaker in a 3rd grade classroom), we are finally attempting to understand the "human terrain" and target the core grievances of the population—chief among them security, dispute resolution, and economic options. None of this means we've effectively addressed these issues, but at least we're starting to consider them. The first step to recovery, as they say, is recognizing you have a problem. This approach is admittedly a tight rope, as we mustn't underestimate the enemy's enduring influence in the process (insurgent combined strength estimates range from 25,000 – 40,000).
This issue also ties back to political primacy. We can kill all the bad guys in an area, but if the perceived (and very basic) needs of the population are not eventually addressed by some form of government, atmospherics will remain ripe for insurgent exploitation. With or without security, insurgents use their knowledge of local dynamics to exploit basic, and inexpensive, issues like land disputes (which are ubiquitous here) and drought (which has hit Afghanistan for the past three years). Issues like this, left unaddressed, can be far more dangerous to stability than an active Taliban cell.
Intelligence Drives Operations. A Marine in Helmand Province recently put it well: "the insurgents have more or less fallen on their backs in the south." Our surge there, accompanied by a comprehensive counterinsurgency strategy, has created protection for the people, leading to relationships, trust, and ultimately information and intelligence. As a result, Marines in the south are raiding the right homes and capturing the right people, slowly degrading Taliban networks and influence there. This approach—driven by the intelligence gathered through effective counterinsurgency operations—is much more effective then more conventional operations focused only on attempting to find bad guys, and defeating them in pitched mini-battles. On the Afghan side, their domestic intelligence agency (NDS) is contributing more and more to targeting, and initiating independent operations.
Ironically, however, our highly successful efforts to kill Taliban and Haqqani Network commanders sometimes have a perverse effect. In some cases, we are killing/capturing the very people who would be most likely to engage in any future negotiated "peace" process. Some of the old guard—who have indicated willingness to talk—have been replaced by younger, more radical commanders. Many of the new guard were born and/or trained in Pakistan, with little regard for traditional—and moderating—tribal codes of honor. Many are more hardline, ruthless, and indoctrinated than their predecessors. This doesn't mean we should stop killing Taliban, but it reminds us how much grey area exists on a battlefield that we'd all prefer to see as black and white.
Insurgents Must be Isolated From Their Cause and Support. In order to operate, insurgents require population support (or capitulation) along with some level of external support and financing. As we work to degrade their population support by clearing areas and creating the space for Afghan control/governance, it's not immediately clear that we're limiting their external support or cutting off their financial lifeblood. We have attempted to strengthen a layered defense along the Pakistan border—especially in the east—but fighters are still able to safely travel across the border to conduct attacks, and then slip back into Pakistan to rearm and refit. Likewise, the Taliban's coffers are not empty. This year is projected to be one of the largest poppy crops in Afghanistan's history, from which insurgents will pull multi-millions in "taxes." Until we're able to isolate the Taliban and Haqqani Network from sanctuary in Pakistan and financial resources from the drug trade, we will have trouble turning temporary tactical gains into durable security. These are huge problems, for which I don't currently see an enduring solution.
Security Under the Rule of Law is Essential. According to a United Nation's survey from late 2010, "three in five Afghans see the police as corrupt, more than a quarter have personally seen a policeman use narcotics, and more than half think filing a complaint will have no effect—or make it worse." If the people don't believe their government and security forces will secure them, or even follow the law, it's tough to change the population's perception of the government. Our training mission is working very hard to create a competent police force, but it's an uphill battle. Illiteracy (and for some, innumeracy!), low pay, short training (6-8 weeks), and worse—a culture of being "above the law"—retard progress in this area. As a result, a growing list of unresolved police violence and corruption cases exist—further alienating the people from their government.
Additionally, Afghan judicial systems are almost non-existent at the local level. Corrupt judges are common, and while some stable provinces have judges, that doesn't mean they equitably uphold the law. By contrast, the Taliban is often able to provide swift justice at the village level. Even if the people don't want the Taliban, they're willing to accept rulings that provide resolution to longstanding disputes. In the courts, and across the Afghan governments, we're doing our best to confront this ineptitude and corruption. A newly formed entity—called Shafafiyat (or "transparency")—has had some success in identifying and exposing corrupt officials, but prosecutions lag (the Afghan Attorney General has prosecuted zero cases). There are signs of gathering momentum, hopefully bringing a sunset clause to the wild west of impunity.
Counterinsurgents Should Prepare for a Long-Term Commitment. As I mentioned in my previous email, the date "2014" rolls off the tongue of most everyone in Afghanistan—the population, insurgents, and counterinsurgents. Coalition efforts are geared towards that date, and our actions gauged in relation to its pressures. General Allen is transparent about the requirements ("I gotta take out 10,000 troops by December 31 and then another 23,000 by September 31 of next year"), but at the same time emphasizes that transition is not an end in-and-of itself, and the "successful application of combat power within counterinsurgency will facilitate transition." Despite this correct formulation, we've seen this movie before, and it looks a lot like was Iraq in 2006. General Allen—and all of us—are determined to prevent that outcome by keeping up the pressure on the enemy and continuing to pursue our objectives while training counterparts who will continue the fight in perpetuity.
Even under the firm 2014 timeline, we still have a strong card to play. A strategic partnership between the U.S. and Afghanistan—which could happen ahead of the forthcoming Bonn conference—would codify our extended commitment, establishing a long-term partnership/presence in order to keep hard fought gains and continue to develop Afghan governance and control. Such a commitment—which would require minimal troops (mostly advisors, enablers, and special operators)—would be a smart way to ensure that our substantial investment here, in blood and treasure, is not ceded to the Taliban by a hasty exit.
That's it for the principles; and, admittedly, this rundown doesn't present a rosy picture of the war. To this, I say two things: First, do not underestimate the impact of our surge efforts—the Taliban in the south has been badly battered, and their momentum arrested. Likewise, the Haqqani Network in the east is taking a pounding, especially from our special operators. As the people sees the enemy being degraded, this will change the population's calculus—both toward us, and toward the prospects of their Army and government. We are creating the space, now they must seize it.
Second, we cannot afford to be prisoners of the moment, and we certainly cannot assume a linear projection of where we are now. Remember the lessons of Iraq: all it takes is one group in one area taking a stand—and properly supported—to induce a "game-changing" opportunity. Small groups around the country—especially where Afghan local police have been stood up—have started to fight back. Likewise, political developments (like a strong parliament effectively checking the president) provide a glimpse of political possibilities. It's too early to tell whether such opportunities will take hold, but many different scenarios—good, bad, and otherwise—are conceivable.
Finally, all that said, we may also have to come to terms with a modified definition of what constitutes "success" in Afghanistan. Michael O'Hanlon, an insightful foreign policy expert at the Brookings Institute, used this formulation:"I think an optimistic, hopeful outcome is nonetheless one in which some pockets of insurgency persist after 2014, but are contained and hopefully degraded over time primarily by the Afghans themselves… For us the key is that no large sanctuaries develop." This simplified formulation protects U.S. interests, and is possible with enduring commitment, the right strategy, and capable Afghan partners. We shouldn't be afraid of moving the goalposts, but not at the expense of our own security.
That's it—now back to work; thank you for reading and have a great Labor Day weekend.
Pete Hegseth


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Next Episode of Dixon of Dock Green is
not planed. TV Show was canceled.
Dixon of Dock Green was a BBC television series about daily life at a London police station, with the emphasis on petty crime, successfully controlled through common sense and human understanding. The central character was a mature and sympathetic police constable, George Dixon, played by Jack Warner in all of the 432 episodes, from 1955 to 1976.Dixon was the embodiment of a typical 'bobby' who would be familiar with the area and its residents in which he patrolled and often lived there himself. The series contrasted sharply with later programmes such as Z-Cars, which reflected a more aggressive policing culture; however its popularity cannot be underestimated, retaining a faithful following throughout its run and being voted second most popular programme on British TV in 1961.
Jack Warner(PC George Dixon)
Peter Byrne(Det. Sgt. Andy Crawford)
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Your little Ole Miss fan may not know anything about sports right now, but that doesn't mean you can't teach them. This Start 'Em Young tee lets everyone know just what team they'll support in a few years. It features "Start 'Em Young, Raise 'Em Right" bubbly lettering surrounding a vibrant school name!
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How to optimise your business comms
It's not about the bills, baby
On Demand No doubt you've got comms bills for your business that, one way or another, you want to simplify, control and reduce - while balancing them with the increasing demands of your organisation. It's not just that everyone has mobiles which is a challenge - they've become the norm so you're probably coping anyway. But what about global IM, solid email, SaaS apps across mobile platforms and all the rest? It doesn't get easier as time goes by that's for sure.
The billing side of comms might be one of the key drivers for a review of the operations, but when it comes to implementation, it's arguably one of the last things you should be thinking about - certainly that was the thinking from our recent webcast. Last week we had Jon Collins from Freeform Dynamics in a studio with our man Tim Phillips and Jeremy Sneller from NEC. They were joined by 150 live viewers from The Register readership and together they thrashed out the idea of optimising business communications in the modern business.
The three of them look at the unfulfilled promise of unified comms and then get into the real meat and potatoes - taking the approach that comms should improve decision-making and collaboration and by using this goal as the start of a project you can deliver significant value. It is, of course, all about harnessing the right kit at the right point in a process and driving benefits from there.
The one hour session received some great feedback from the viewers. The session also goes through a lot of the data that was produced from a Reg reader survey - so it's all real world data from people that are managing comms in their business. It makes for compelling viewing.
They conclude with some straight talking on whether it's all actually worth the effort. Judge for yourself right here. ®
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Facebook wannabe: Container Store IPO a total flop
- Commentary
- Posted By Cody Willard
Amazon is still smartly plowing its revenues back into its businesses to fuel topline growth so that eventually earnings will be even bigger than otherwise. But what a market cap $AMZN sports now, at $165 billion. Time to trim this one, in a tranche-kind of way, taking some maybe about 1/5 or 1/4 of our shares off the table and holding the rest steady for the long-term.
Don't despair though, there are ways to get through this. There are always signs when a business is headed downhill, such as whether they can't pivot to a new technology, or management is stubbornly convinced that they need to fight old battles. Over the last couple years finding short cases has become an increasing part of what I do and we've had several substantial winners. In the case of A123 systems I targeted a company with a blazing hot IPO that was nothing more than shell to funnel off taxpayer money. Here's what I said in December of 2010, before AONE's 75% decline.
Cody Willard writes the Revolution Investing investment newsletter for MarketWatch and posts the trades from his personal account at TradingWithCody.com He is the founder of WallStreetAll-Stars.com and the principal of CL Willard Capital. Cody serves as an adjunct professor at Seton Hall University and is on the University of New Mexico Alumni Board. He was an anchor on the Fox Business Network, where he was the co-host of the long-time #1-rated show on the network, Fox Business Happy Hour. Cody, a former hedge fund manager, and his stock picks and economic outlooks have been featured on NBC's The Tonight Show with Jay Leno, ABC's 20/20, CBS Evening News, CNBC's SquawkBox, Jon Stewart's The Daily Show, as well as in the Financial Times, Wall Street Journal, New York Times, and many other outlets.
You can follow Cody on Twitter:
Follow @codywillard


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CATIA for Engineers enables Digital Prototyping including Analysis and Simulation for design and validation of function quality and performance at all stages ofthe design.
Mechanical engineering is complex as assemblies are designed to perform a specific task with a specific target performance. Digital prototyping, combined with digital analysis and simulation, allows product development teams to virtually create and analyze a mechanical product in its environment. Mechanical engineers must be equipped with these tools so that they can gain insight into key factors in quality and performance early in the product development phase.
CATIA Piping and Tubing Design
Provides 3D tools to create, modify, analyze, and document piping designs
CATIA Piping and Tubing Design creates and manages the physical designs of piping and tubing systems using industry standards and specifications, within the context of a full digital mock-up.
It also provides tools to define the physical system of both rigid and flexible pipes and tubes from basic routing definition to detailed design. This is made possible with the help of intelligent part placement based on standard and design rules that comply with company knowledge. In addition, its tools make it possible to quickly query design information and generate reports based on any component parameters. A full digital mock-up ensures design precision while saving time, minimizing errors, and reducing expenses.
Together with CATIA V6's data management offerings, this product empowers users to manage their systems all the way from functional design down to detailed design.
- Model and customize objects with "smart" features
- Design with a highly interactive and intuitive user interface
- Integrate business rules
- Explode piping and tubing objects, attributes, and relationships in the V6 database
- Access full traceability with RFLP approach
Creation and management of pipes and tubesUsers can create pipes and tubes with standard industry attribute information. In addition, designers can create their own attributes to be included in pipes and tubes definitions.
Function-driven piping and tubing part placementUsers can capture the design intent for selected physical parts to ensure that modification scenarios are possible. Designers can layout and model a 3D piping or tubing network either manually or automatically. If parts are based on user-defined rules, such as branching or turning rules, much of the layout can be created automatically to optimize the total design process.
Evolution from preliminary to detailed design layoutPreliminary layouts can evolve into detailed designs using standard piping parts and specification catalogs. Using this methodology, designers can progress to the final layout stage with greater speed and accuracy.
Integrated dynamic design rulesDuring the preliminary and detailed design process, rule-based design checking actions are automatically launched to validate the proposed design. Users can modify existing samples, or create their own rules, to control the graphic representations of objects via knowledgeware rules. After design creation, the user can still validate the design using a dedicated manufacturability checking command.
Intelligent modification of piping and tubing objects and routesUsers are able to revise layouts and change route segments and nodes using offset and clearance capabilities. Piping and Tubing parts and routes can be directly manipulated by pushing and stretching points, segments and extremities. Connectivity is managed through connect and disconnect tools. Piping and Tubing part modifications propagate changes that will impact the design intent. Similarly, a specification change will force a new part selection and placement.
Query and analysis of piping and tubing parts and configurationsKey properties are readily available to the user at element pre-highlight. Users can perform a wide variety of queries and/or analysis to inquire about the specific properties of any object in the design document. Through a network analysis tool, designers also have the ability to query and analyze tubing connectivity.
Customizable report definition and drawingsA dedicated report definition capability allows the user to tailor the definition of the reports based on company standards. This definition can be accessed as needed, any time during the design process. Specific tools also allow the customization of the drawing format for single and double line display. The user can customize corporate data and define rules that will enforce company standards, such as defining piping and tubing specifications and geometry definitions, as well as equipment catalog building.


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All Time Box Office
华东联网15选5走势图 www.ylzrt.com DOMESTIC GROSSES
^ Indicates documented multiple theatrical releases. Most of the pre-1980 movies listed on this chart had multiple undocumentented releases over the years. The year shown is the first year of release.
Most pre-1980 pictures achieved their totals through multiple releases, especially Disney animated features which made much of their totals in the past few decades belying their original release dates in terms of adjustment. For example, Snow White has made $118,328,683 of its unadjusted $184,925,486 total since 1983. Click here for a full discussion of adjusting for movie ticket price inflation.


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Lauren Simpson
Clinical Assistant Professor
Professor Simpson earned her B.A. in French and International Studies (cum laude) at Washington University in St. Louis, Missouri in 1988. She obtained her J.D. (cum laude) from the University of Houston Law Center in 1994. While at the Law Center, Professor Simpson received the award for Best Speaker in the John Black Moot Court Competition and also participated in multiple interscholastic moot court competitions. She was admitted to the Texas Bar in 1994. From 1994 to 1997, Professor Simpson was an associate at Meyer, Orlando & Evans, P.C. She transitioned to the First Court of Appeals of Texas in early 1997, serving there as a staff attorney for more than 13 years.


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The Daily Word in marriage rights, Romney the bully and breastfeeding
Justice Department accuses infamous Arizona sheriff Joe Arpaio of trampling civil rights in his district.
President Obama announced his support for full marriage equality, but New Mexicans don't see it happening anytime soon.
There were Christian same-sex unions in the 10th century, says anthropologist.
Kid fell into the zebra exhibit.
Former APD union boss arrested and charged with domestic violence.
With few protections in the state, some people wind up purchasing land from folks who don't own it.
Mitt Romney was a bully and a cutter of hair he didn't like.
A man in his undies stabbed his computer with a samurai sword while police were looking for child porn.
Time magazine's breastfeeding cover.
What would it be like if pterosaurs walked the Earth right now.
Fancy business types are annoyed by the way Facebook's Mark Zuckerberg dresses.
Fundamentalist Phoenix high school forfeits championship baseball game because the other team had a girl on it.
South Korea accuses North Korea of jamming GPS signals for civilian flights.
This dog is ready to play.
Double-face white shark coffee table.
Hack your triggers.
Humpback whales defend baby gray whale from orcas.


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OK, gotta ask. "Fireweed"??
As has already been noted, we spent the 2002 anniversary of 9/11 in Hyder.
We are seriously re-thinking the time table for the trip. I think we need to start a little earlier and stay a little longer. We just will skip the GNR next year and return in 2013. I want to give Alaska all the attention we need to make the trip worth while. Thanks for the heads up!
Thanks Betty, I believe you are right!
There's a bunch of History that's worth your time.
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