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Scenes from a Pizzeria: Antonio Starita's One-Night-Only 'Secret Show' at Kesté
It was late in the day on Friday when Slice learned that Antonio Starita of Naples's Pizzeria Starita would be in town making pizzas at Kesté Pizza & Vino for one night only.
Starita is an instructor at the Associazione Pizzaiuoli Napoletani, the Naples-based governing body that both teaches pizza-making and certifies pizza-makers as adhering to authentic Neapolitan ways.
Why Kesté? Among Starita's protegés is Kesté's Roberto Caporuscio, who now works as head pizzaiolo at Kesté and who teaches and certifies aspiring pizza-makers on this side of the Atlantic for the APN.
Starita was on his way back to Naples from the International Pizza Expo in Las Vegas and decided at the last minute to work the dough alongside Caporuscio in a sort of one-night-only pizza supergroup secret show. Here are photos from the evening.
This post may contain links to Amazon or other partners; your purchases via these links can benefit Serious Eats. Read more about our affiliate linking policy.


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Kimberly Oliver Burnim
Kindergarten and First Grade Teacher
National Teacher of the Year, 2006
"Research has shown that children learn more from birth to age five than at any other time in their lives. Children who complete the curriculum of ABCmouse.com during those all–important formative years will be very well prepared for kindergarten, and that can make a very big difference in the rest of their schooling."
Dr. Rebecca Palacios
Pre-K Teacher for more than 25 years
Founding Director of the National Board for Professional
Teaching Standards
"Parents want to help their young children learn, but may not know where to turn for the right educational resources. If I could recommend only one online resource to parents of young children, it would be ABCmouse.com, without a doubt."

subset: commoncrawl


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Hi All,
I am now spending a bit more time focusing on this strange little book, more out of interest in Elubatel than anything else, but so far it has had some pretty strange effects. There is on the surface not much to this book, I remember almost falling asleep the first two times I read it thinking it was a load of contrived crap - basically hebrew transliterated by a bunch of Christian monks. Then I started actually working with it and there is a very deep power here, the kind of power that comes from working with the Grim Verum. I don't really know what I was expecting, I suppose something a little "lighter" in flavour, but hell man, this book calls up some diabolical stuff.
Problem is, this book is not often used, not often written about and I am sure that the version that I have in physical form and pdf is edited beyond belief. The instructions are all contradictory and the book follows no particular path and seems to have no specific purpose. It kind of jumps from talismanic magick, to summoning the plagues of Egypt, to summoning spirits, most of which I have never heard of. So my question is, how do you guys use this book?
1) Has anybody bothered to go and get the laurel crown and palm twig and do the Principal Citation (that is half way through the book). I did, if you get it right, there is a halo, yes, you start to glow!
2) Has anybody actually used the General Citation? I did, with and without the Principal Citation and if you don't take it seriously it does some pretty rough stuff
3) Has anybody used the Rabellini Table for summoning any spirit? I did, without using 1 and 2 above and with no other preparation and low and behold, there stood a spirit. Kind of wish I had used the circle, made me a bit grumpy for a few days
SO, anybody else use this little book?


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amfAR, The Foundation for AIDS Research
Dr. Nittaya Phanuphak (center) of the Thai Red CrossAIDS Research Centre with study physician Dr. NipatTeeratakulpisarn and study nurse Ms. Amornrat Sukjitpaiboonphol.
March 2011—Confronting the increasing burden of cancer among people living with HIV/AIDS in Asia, TREAT Asia co-sponsored a two-day symposium in November bringing together regional and global experts with the aim of deepening understanding of cancer and its relationship to HIV.
"People with HIV are living longer because of highly active antiretroviral treatment [HAART], but because they have a higher risk of developing certain cancers associated with other viral infections, they can still die younger," said TREAT Asia Director Annette Sohn, M.D. "The situation is amplified in Asia and other resource-limited regions where cancer is hard to diagnose and treat since medical resources are not usually available."
Because of the strong association of human papillomavirus (HPV) with anal and cervical cancers, a number of presentations addressed current research into these two illnesses. Studies have shown that HIV-positive women and men who have sex with men (MSM) are much more likely to have HPV-associated cancers. In the US, HPV is now preventable through a childhood vaccine, but the cost is prohibitive in Asia. "We don't have the infrastructure in Asia for cervical cancer screening in the general population, but it's desperately needed among women with HIV given the much higher risk," said Liesl Messerschmidt, TREAT Asia's director of research.
High rates of HPV-related anal dysplasia have been identified by the Thai Red Cross AIDS Research Centre in Bangkok via a screening program supported by TREAT Asia through a grant from the US National Institutes of Health's IeDEA (International Epidemiologic Databases to Evaluate AIDS) program.
The Thai study has raised significant concerns about the extent of anal cancer risk among MSM, according to principal investigator Nittaya Phanuphak, M.D. The study is now looking at proteins associated with anal cancer in order to determine if men who are more likely to progress to cancer can be more accurately identified. The Thai Red Cross's research is rapidly advancing the understanding of anal cancer risk, progress that is leading to opportunities to collaborate with other US and Australian investigators.
Another area of growing interest in Asia is liver cancer associated with viral hepatitis infection. Many of the local HIV epidemics in the region are connected with injection drug use and studies show that upwards of 90 percent of IDUs in Asia can also be infected with hepatitis C, which puts them at risk for liver cancer; this risk is even greater in the context of HIV infection. But because the costs of treating hepatitis B and C are prohibitively high, local clinicians lack the tools to help patients who may have more problems with liver disease than with their HIV infection.
The symposium, which was supported by the IeDEA program, brought together 61 participants from nine countries to hear presentations from the World Health Organization's International Agency for Research on Cancer; the US National Institutes of Health's National Cancer Institute; regional medical centers and universities; and Australia's National Centre in HIV Epidemiology and Clinical Research, which co-sponsored the symposium.
© 2019 amfAR All Rights Reserved || amfAR's mission is to end the global AIDS epidemic through innovative research


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Details Of Border Wall Deal Emerge
A tentative bipartisan deal on border security would provide far less funding for a border barrier than President Trump has asked for. Lawmakers reached the deal late Monday in hopes of avoiding another government shutdown by the end of the week. The deal includes over $1,000,000,000 in funding for a physical barrier at the southern border, which is a far cry from the nearly $6,000,000,000 Trump demanded. The agreement also limits funding for detention beds for people in Immigration and Customs Enforcement custody. However, the deal includes funding for a limited number of detention beds, just over 40,000. Legislators face a deadline at the end of this week to reach a deal or risk another shutdown.
Photo: AOL


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5. Prepare for hair highlighting by assembling materials.
Gather everything you need to apply the highlights so that you do not have to stop halfway through the process to get something you forgot. Set everything near the sink you will be using, including a towel and perhaps old rugs or newspapers on the floor to catch drips or spills. Wear an old shirt to protect your better clothing. Make sure other family members will not need to use the area, or the sink, anytime soon, since you will be using it to apply hair highlights. Set out the tools and products in the order you will need them.
6. Use appropriate supplies and tools.
For foil wraps, get the kind salons use at a beauty supply shop. To streak highlights into your hair, buy one-fourth-inch and one-half-inch acrylic brushes from an art supply store. Close-fitting latex gloves can protect your hands, unless you are allergic to latex. Buy another kind, if you are sensitive to latex, as there are other types of cosmetic product gloves on the market, as well. Have a plastic hair cover ready, such as a shower cap, although one usually comes with the highlighting product.
7. Apply highlights as suggested.
Of course, you are free to apply color wherever and however you like. But you may want to try a traditional application before getting overly creative to make sure you are satisfied with the resulting shade and the overall effect. Some experts suggest that you begin at the back of your head and work your way to the front and sides, highlighting only the top layers of hair in thin strands that will blend naturally with the rest of your hair.


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Rochester MI's Leading Clinic For Laser Hair Treatment
Combat Hair Loss with Laser Hair Treatment from Shear Pointe Medical!
Hair loss affects millions of men and women worldwide. When people begin to notice their hair thinning or balding, this can cause some frustration and a drop in confidence. However, the surgical options and side effects of a hair transplant may be a turn-off to some. With all the hair regrowth options, it can be tough. Luckily, at Shear Pointe, we have an option for those who want a non-surgical solution- laser hair treatment.
For men and women who are suffering from baldness or thinning hair, laser hair therapy is a proven alternative option! It's now easier than ever to have fuller, shinier and healthier hair. At Shear Pointe, we use the Lasercap® LCPRO™ which is a low-level laser. Low-level lasers are soft lasers that don't have the thermal-component to cut, burn or vaporize, so your skin is safe from any harm.
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Aside from being non-surgical, there are many reasons our guests choose laser hair replacement therapy. Choosing laser hair therapy is a safe, easy and painless solution to thinning or balding hair. There are no known side effects in correlation with low-level laser light hair therapy. Developed in Europe, low-level laser light has been used for many hair-related uses, such as improving the quality of the hair shaft and volume.
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Rock Band Country Track Pack 2 is a standalone software product that let's country music fans master guitar, bass, drums or vocals on 21 seminal country hits, hand-picked with care by Harmonix . This Track Pack can be played on its own in single-player, competitive, or collaborative band modes, and includes the added bonus of having the option to export all 21 songs from the disc into your Rock Band®, Rock Band® 2 and Rock Band® 3 music library*! This Track Pack is also compatible with all Rock Band and most other music game instrument controllers.
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A legally blind man had a personal request after being acquitted of shooting and killing his friend in Geneva, Florida.
He wanted his guns back.
John Rogers, 40, was charged with first-degree murder in the shooting death of James Dewitt, 34, in March 2012, the NY Daily News reports. He was acquitted after a judge ruled the former Marine had acted in self-defense and was in accordance with Florida's "Stand Your Ground" law.
Reportedly, Dewitt and Rogers were involved in some kind of brawl which resulted in Rogers shooting his friend with a .308-caliber rifle.
Following the acquittal, the judge reluctantly granted Rogers' request to be reunited with his guns, WESH-TV reports. He did destroy all the ammunition because it was old and dangerous.
"I have to return property that was taken under the circumstance," Judge John Galluzzo said. "I have researched and haven't found case law to say otherwise."
He later told the Orlando Sentinel that if it were "his" decision, he wouldn't have returned them.
Rogers hopes the controversy surrounding Galluzo's decision ends there.
"The family has been through enough, and I have been through enough, and I would like to retire, put this behind me and move forward," Rogers said.
Below is a gallery of notable criminal cases out of Florida.


text: Common Questions Are my headaches caused by my eyes? Headaches are only rarely caused by eye problems, even if the pain feels like it is coming from or behind the eye. One explanation for this perhaps surprising statement is that the eye socket is often the site of "referred pain", that is, a sense of discomfort in one part of the body because of a problem that is truly elsewhere. This is similar to the occurrence of left arm pain in patients who experience a heart attack. The need for glasses is not commonly an explanation for headache, although you might feel "eye strain" or tire more easily if a better prescription for glasses is needed. Headache should be distinguished from true eye pain, which is usually localized to the surface of the eye, and is most commonly caused by dry eyes. Can anything be done to restore my vision? Visual loss occurs because of either optical or neural problems. Optical causes of visual loss [such as refractive error (need for glasses), cataract or corneal opacities] can usually be corrected or significantly improved. Nerve damage (for instance to the retina or optic nerve) cannot be repaired. Researchers around the world, however, are working on many strategies to restore vision to patients who have suffered damage to the retina or optic nerve. To date none of the laboratory techniques have been significantly successful in this quest. Do I need to see an eye doctor if I lost vision, but it returned to normal within a few minutes? Yes, definitely you should be examined by an ophthalmologist as soon as possible. Temporary loss of vision that persists for at least several minutes can be a sign of interruption of blood flow to the eye. Temporary visual loss can be followed by visual loss that is permanent. By analogy, a few minutes of chest pain can be a sign of an impending heart attack, and the importance of contacting your doctor in this situation seems obvious. The same concern should be given to visual loss that persists for several minutes or longer, even if visual loss is confined to one eye. Not all causes of temporary visual loss are serious. In fact, migraine is the leading cause of temporary visual loss (even when not accompanied by headache) and vision almost always returns to normal with migraine. Will I weaken my eyes by wearing glasses? No. You should wear whatever prescription is determined to be correct for your eyes. You will not harm your eyes if you do not wear your glasses, and you will also not harm yourself if you do use your glasses. The notion that wearing glasses weakens your eyes derives from the common observation that people who begin to use reading glasses typically need to increase the strength of the prescription after a period of a few years. This need for added strength happens because of an age-related change in the lens of the eye. It is natural to need stronger reading glasses at age 60 compared to age 40. Can I strengthen my eyes with exercises? No. Exercising your eye muscles does not improve their ability to focus or move from side to side. This might seem counter intuitive, since all other muscles of the body can improve their performance through exercise, but the muscles of the eye are different. The difference might partly result from the fact that the brain provides very precise control for eye position and exercising the muscles does not influence the signals coming from the eye to the brain. Make An Appointment Today! 617-573-3202


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Oscar-nominated Jennifer Lawrence, who played the scaly blue super-heroine Mystique in "X-Men: First Class" has revealed that meeting John Stamos at a recent party was among the highlights of her life – even though she acted like a stalker.
Ironically, Stamos was once married to Rebecca Romijn, who played Mystique, aka Raven Darkholme, in the first three "X-Men" movies. Lawrence admits her encounter with her longtime crush wasn't quite as she'd planned it.
She tells Conan O'Brien, "He was at a party and I turned into a perverted guy; I was, like, following him into rooms, like, staring at his a**.
"I was avoiding him and then my friends brought him over … and I just, like, started really freaking out and he asked me if I was on mushrooms. I was like, 'No… this is just me!'"


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A friend of mine would like you guys to look at his team and express your views, what can he do to make it better, etc. All views are appreciated. also, if you could compare my team to his, I would appreciate it, just to let me know how I can improve if need be. We play in a 10x10 h2h league, thanks for all replies.
HIs team-
1B- Helton
2B- Soriano
SS- Rentaria
3B- Hinske
OF- Matsui
OF- Encarnacion
OF- Floyd
Util- Jose Vizcanio
Bench- Learns, Cedeno, Simon
Starters- Mulder, Prior, Burnett, Padilla, Sabathia, Isshi, Fossum
Relievers- Guardado, Mesa, Looper, dejean
My Team-
C- Hall
1B- Derek Lee
2B- Durham
SS- Jeter
3B- Rolen
OF- Abreu
OF- Hunter
OF- P. Wilson
Uti- Phelps
Bench- V. Wells, Crede, Cabrera
Starters- Pedro, W. Miller, O. Perez, Beckett, Hampton, Moss
relievers- Rivera, Baez, Hoffman(IL), F. Rodriguez, and Latroy Hawkins
Thanks for all replies


text: The atomic rates for H and He-like ions are accurate for densities up to cm by taking into account the effects of 3-body recombination and lowering of the continuum ([Bautista et al. 1998], [Bautista et al. 1999]). However, these effects are not treated for other species which reduce the accuracy of the model results for these ions at high density. The density for which these effects become important for a given ion increases rapidly with effective charge of the ion, starting at about cm for z=1 and at about cm for z=8. At low densities numerical errors can occur; the user is urged to read chapter 6.


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Mark Mawson's Explosive Photos of Neon Ink in Water
Expanding on his awe-inspiring Aqueous collection, which we spotlighted a while back, photographer Mark Mawson has returned with a newer, brighter, absolutely gorgeous addition to his series of ink-in-water shots. Titled Aqueous Fluoreau, the Sydney and London-dwelling artist's latest batch of photos stray from the sea creature-reminiscent shapes from his previous works, steering towards a more explosive aesthetic. Neon pink, yellow, and aqua hues pop against a black background as they take on the shape of mushroom clouds and swirl together, creating a vibrant, kaleidoscopic visual. Get lost in the Mawson's creations after the jump, and check out his website for more.
Photo credit: Mark Mawson [Spotted via Colossal]


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My second attempt at making goat, a leg roast is coated with papaya seeds to tenderize the meat.
When my first attempt (braised goat in coconut and rum) came out of the oven, I was staring at lumps of grey meat bathed in a curdled gray sauce. This was definitely NOT awesome! Tasting it only made it worse. I hate throwing food away, but that was the only place fit for this dish! I didn't take a picture because I was too stressed out and embarrassed, but I wish I would have because it was DISGUSTING!
I knew goat was a lean meat which could be tough, so it would be best to slow cook it with a liquid to help it keep moist, which was the impetus of my first attempt. For an island effect, I chose rum and coconut milk. Well, I'm still not sure what part of the body those cuts came from, but they were tough grisly and grotesque. The rum was not acidic enough to help tenderize the meat and coconut milk, upon continuous cooking, apparently curdles. I guess goat has a tendency of turning gray when cooked and the white cooking sauce, surely didn't help its color. It looked horrible and tasted disgusting. This recipe SUCKED! I was a bit stressed out.
It seemed the obstacles I needed to work around for this recipe was:
- keeping the meat tender and avoiding tough chewy meat
- avoiding the gray color which is unappetizing!
After my last fiasco, I wasn't taking any chances with texture problems, so I decided to marinate it overnight AND apply a dry rub for a couple of hours before cooking to ensure a moist tender roast. I had previously marinated my first attempt in rum only, which I figured wouldn't be enough. I decided to add fresh lime juice which would pump up the acidity, and I added olive oil, to help infuse some fat into the lean goat meat.
But now color. Gray meat just looks gross. If I was doing a red wine marinade that would give it color, but I wanted to stick with tropical flavors (rum, lime etc). I started thinking of other things I could use for color, and I finally thought of one of nature's most powerful natural dyes: beets! Although not authentic to Polynesia, I added beets to the marinade to give this meat some color.
Leg roast for the event on the grill. You can see the ginger, garlic and lardoons sticking out in areas around the roast.
It worked. The morning after its marination, I found what looked like a tandoori leg of goat! Even more so, it was purple! Well, I thought the meat would definitely not be gray. Ha!
I had also been instructed by my Aunt to cut away the thick white fat around the edges of the leg and reserve them. I now pulled them out of the fridge. With my paring knife, I cut slits an inch or so into the flesh of the roast and inserted the fatty deposits, which we can be all fancy and refer to as "lardoons". I also stuffed some garlic cloves and ginger into the pockets with the lardoons to infuse a bit of awesome. I finished by applying my dry rub, which used papaya seeds as a binder. I wrapped the pup up and put in the fridge, to chill for 3 hours or so.
To trap all the juices which I had been obsessing about infusing into the meat, I decided to sere the roast first. You can start the roast in the oven at a really high heat like 450 and turn down to 300. But I wasn't sure that was enough. I wanted to make sure this meat SEARED.
SO Ira and I set up our small BBQ with a huge pile of coals red HOT! By starting the roast off on the BBQ, not only were we able to sear it, but also infuse a bit of smokey flavor and give the surface of the roast a nice blackened look. I gave each side 5-10 minutes on the grill (15-20 min. total).
After the grill, I inserted the meat thermometer into the thickest part of the meat. Putting my blackened purple leg roast back into a roaster pan over some chopped onions to keep it from burning to the bottom, I quickly got it into the oven at about 325 to finish cooking. I spooned some of the marinade over the top for good measure. At this point, I just waited with fingers tightly crossed until the thermometer registered 130.
Roasts will continue to cook after its taken out of the oven, so by removing it at 130, I could ensure to end up at my preferred temp of a medium rare 140 degrees. I thought the roast would take a few hours as did the recipes I had read online, so I was a bit surprised when I hit 130 after only 90 minutes. I guess the BBQ really put a jump start on the cooking. I took the roast out of the oven, and "tented" it by loosely covering it up with aluminum foil to rest, about 10-20 minutes.
When I finally carved into the roast, I was jumping for joy. It was the most moist, delicious meat I had ever seen and tasted. The beautiful mild flavor was not overpowered by the marinade. Although purple on the outside, the meat had a delicate pinkish color which only added to its appeal. Thank you beets! A sigh of relief, I had my entree recipe figured out.
It was a close gross call, but the dish we ended up with was filled with absolute goaty awesomeness!
Here's the recipe.


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These words might seem familiar. Indulge us, because Iron Bowl day comes every year.
These words might seem familiar. Indulge us, because Iron Bowl day comes every year.
This afternoon at Bryant-Denny Stadium, the Alabama Crimson Tide and Auburn Tigers will meet for the 77th time on the football field.
If one believes the oddsmakers, and looks at how the respective seasons have played out, it shouldn't be much of a game, even with the old "you can toss out the records when these teams play" mindset.
Alabama is 10-1 and has a chance to win its second straight BCS national championship and its third in the last four years.
Auburn, just two years removed from a national title of its own, is 3-8, and there's talk of a coaching change and about NCAA investigators nosing around in Lee County.
Those things will play out as they will. Our focus is on today's game — more specifically, on keeping things sane where today's game is concerned.
Old-timers might disagree and say it's only because fewer eyes were watching back then, but we think this rivalry has gotten awfully nasty in recent years, to the point of alleged criminal vandalism.
Much of it probably stems from "more eyes watching" — on Internet message boards and forums and through social media — and being able to do it around the clock.
We'd cite a healthy dose of "gums flapping" as well, on the incessant sports talk shows (with both pundits and callers offering their respective 2 cents' worth, which often fail to reach that valuation) that help keep radio alive these days.
There's also the monetary stakes, which are a lot higher than when Paul Bryant and Ralph Jordan were running the respective sidelines in this game.
We're not going to mount our high horse and sniff "this is just a football game." We realize sports aren't going to fix the economy, cure diseases or bring about world peace, and that some people never will "get it," but Alabamians should be unashamedly proud of this state's record of success on the gridiron. There also are many positives to the unique intensity and passion of the Alabama-Auburn rivalry.
The key is not letting that be overwhelmed by the negatives.
Enjoy the game today. Cheer for your teams and coaches (who traditionally get along better than the respective fan bases) until you are exhausted and hoarse.
Celebrate a victory. Shed tears for a loss.
Stay safe, be smart — and think before you talk or act.


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Beautiful, and "welcome" from one newer member to another! A vertical crop of, say, the leftmost 40% or so of this would be stunning as well.
Please don't crop it. First, you'll spoil it; and second, you'll get on the wrong side of Russ Lewis (RSL - you'll come across him pretty soon).Jeremy
Welcome Justin, great image, silky smooth, very nice indeed - I agree with Jeremy no crop needed, although I can see James's point and wonder if you also made a vertical shot of this scene?Dave
Just to clarify - I agree that no crop is needed - I was simply suggesting another composition from the available source material


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Davis Ninth Grade School
Many Aldine employees and families have experienced losses to their homes and automobiles. Please be aware of a new state law, HB1774, that takes effect Friday, September 1. It reduces the penalty interest insurers pay if they stall claims during a lawsuit or make no payments on insurance claims. The new law shrinks the penalty to 10 percent from 18 percent. Policyholders should notify insurance companies about claims before close of business on Thursday, Aug. 31, 2017.


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Earlier this summer, I released a study comparing the performance of California's charter school networks with the amount of philanthropic grant funding they have received. The purpose was to find out if this model for replicating excellence was consistently effective. The answer, regrettably, was no.
But a new study we are releasing today finds that there is at least one place where better schools HAVE consistently scaled-up: Chile. Thanks to that nation's public and private school choice program, chains of private schools have arisen, and they not only outperform the public schools, they also outperform the independent "mom-and-pop" private schools.
For anyone interested in replicating educational excellence, this study by a team of Chilean scholars is worth a look.


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Chardonnay from Zagat collection. Don't normally get chardonnay, but this was tasty and crisp!
More posts
- Medium body cherry nose, bit sweet Cab Sangiovese n Syrah blend, clean finish, good but not great 3* of 5 $26@Baileyana
- A bit hot but w great depth, showing a spicy tannic bite,a great Syrah/tempernillo/grenache blend $24, 4*@ Baileyana SLO
- 2009 CA Chard that's very yummy. Oaked just enough and readily available in PA stores as a Chairman's Selection.
- Amazing med body pinot with great complexity n spicyness $26@ Baileyana Wine Club San Luis Obispo CA. 4* of 5
- Enjoyed this magnum with Andersons, Olsons and Mckiernans! Big red.


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(Posted Thu. Jul 10th, 2014)
Yesterday, the U.S. House of Representatives Committee on Agriculture's Subcommittee on Horticulture, Research, Biotechnology, and Foreign Agriculture held a hearing to explore the societal benefits of biotechnology. The hearing, which featured four speakers, explored how consumers, farmers and the environment have benefitted from traditional and modern applications of biotechnology. Some of the benefits of biotechnology explored include fighting diseases, increasing available food sources and conserving natural resources.
The panel also responded to questions from Committee Members concerning the challenges of relaying factual information about these technologies to the general public.
"It is clear from the hearing today that biotechnology plays a critical role in meeting a number of consumer and societal needs," said Chairman Austin Scott (R-GA) in a statement following the hearing. "In a world where it is important to help feed our expanding population while ensuring that everyone has access to safe, diverse, and quality food, the U.S. can, and should, be a leader in biotech development to address the coming challenges for future generations. Whether it is treating vitamin deficiency, autoimmune disorders or addressing hunger, biotechnology has and will continue to play a large role in global agriculture."
"It was important to hold this hearing on the benefits of biotechnology because the stakes are high and biotech has a great story to tell," said Acting Chairman Rodney Davis (R-IL), who filled in for Scott at the hearing. "Our farmers have the vital job of feeding a growing world and biotechnology is part of the solution. I'm excited for the future and believe the United States must continue to safely innovate through biotechnology to achieve higher crop yields, fewer hungry people and an improved environment."
Panelists included Cornell University Dr. David Just, who serves as co-director of the Cornell Center for Behavioral Economics in Child Nutrition Programs at the Charles H. Dyson School of Applied Economics and Management; John F Kennedy School of Government Professor of Practice of International Development Professor Dr. Calestous Juma, who serves as director of the Science, Technology, and Globalization Project at the Belfer Center for Science and International Affairs; Tuskegee University Assistant Professor Dr. Olga Bolden-Tiller and The Farm at Wheeler Mountain owner and dairy farmer Joanna Lidback.
To view the archived webcast click here.
"The U.S. produces the safest and healthiest food and fiber in the world, and biotechnology plays a critical role as we work to meet the needs of a growing population," said Ranking Member Kurt Schrader (D-OR) in a post-hearing statement. " As science and technology advances, it's important that we don't pit different agriculture production systems against one another – we should support all forms of agriculture. From the creation of seeds that can better withstand drought to the development of fortified rice to assist those suffering from a deficiency of essential vitamins and minerals, biotech is playing a crucial role in our society by feeding the world, protecting our environment and improving global health. Today's hearing made it very clear that we still have a lot of work to do to communicate with the public about the benefits of biotech, and I believe this committee can play a vital role in doing just that."


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Moderator: Granitehewer
Deepcrush wrote:Well that's good, when I looked over the models I only saw what may have been two. One facing forward on the center of the nacelle pylons. Though I have to admit I like her phaser coverage, a lot better then I expected to find.
Deepcrush wrote:Birthplace of the KKK now turned into a ship of exploration and education.
Teaos wrote:To boldly go where no middle class white man has gone before!
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By Vanessa Lewis
There's a new buzz in town, happening in restaurants throughout Southington. Families are talking to each other, thanks to the Conversation Cards initiative by STEPS (Southington Town Wide Effort to Promote Success.) STEPS is an asset based prevention coalition following 40 developmental assets believed to foster healthy development in teens, from anti-bulllying to healthy self esteem to the prevention of drugs and alcohol.
If, after all of STEPS efforts, 35 of these 40 assets are reached in Southington teens, then the Southington Youth Council has found success in its STEPS initiative, the group stated.
The conversation cards came about after Justine Griffin witnessed another family in a restaurant with their heads down, sullen and staring at their iphone and ipad screens, not talking to each other.
She said the kids seemed well behaved, but something still was missing. Justine knew how much she looked forward to sitting down with her own parents and talking about the day, so she wondered if other families could do it as well.
Other council members agreed , and ran with it.
Seventeen restaurants throughout Southington agreed to participate, including Friendly's, Moe's, Pop's Burgers, Family Pizza, Smokin' with Chris, Wood n Tap, Outback, TD Homers, Steve's Restaurant, El Sombrero, Pepper Pot, Fireplace, the Carousel, Spartan Pizza II, the Manor Inn and Renaldo's.
Each deck has 58 cards and features questions to enhance family conversation, such as "What do you admire most about your mother or father?" and, "Name an aspect you like about yourself."
Chris Conlon, owner of Smokin with Chris's was one of the first to sign on.
Conlon was one of ten brothers and sisters and says they sat down every night to a home-cooked meal and conversation.
"A real family dinner seems a lost art in America. I've always been a firm believer of turning off the tv during dinner and talking to your children and parents, about school, friends and to air your grievances."
Here, he says, because of the cards, i phones and I pods are put away and real family conversation is being made while waiting for the food to arrive.
He says STEPS is definitely on the right track and it's up to the parents to continue the conversation.
Heather Medling, manager of Pop's Burgers and Fries in Plantsville said she's glad not as many people are watching the televisions now, while waiting for their food.
"I am noticing a difference in customers, especially teens. A lot more smiles."
Owner Jonathan Salerno, said Pop's loves to help out the community and frequently takes part in restaurant nights where 10 per cent of proceeds is given to local charities.
Steve and Mona Menard who own Steve's Restaurant in Plantsville think the cards are a great idea that they hope more families will take advantage of. "Kids usually just play on the video games" Steve said. "It's nice to see people off their cell phones, realizing they can still talk too. We'd like to see more places pick up on the trend. Customers seem much happier when they leave."
Mona knows firsthand how hard it is to start a conversation with your kids at the dinner table.
As a restaurant owner, wife and parent as well, she said, "Parents and kids are thinking of different things. Kids are thinking about school and parents are thinking about laundry and dishes. My husband and I have been in the restaurant business for thirty five years and some people don't even talk at all while they are eating."
She considers the conversation cards ice breakers.
Eleventh grader and youth council member Natalie Nyerick says cards were chosen based on which would create the most conversation between the family. There even is one wild card where you can make your own question.
What Natalie likes most about the initiative is a lot of the kids that know about the cards like to go to the restaurants that have the cards, because it's more fun, she says.
Parents might initiate the conversation to promote more family time and more positive communication.
"When parents feel more comfortable with their kids, and kids feel more comfortable with their parents, parents might be able to initiate the tougher conversations, like about drugs and alcohol."
It's only been a couple of months, but the last survey that Youth Services did of seventh graders, ninth graders and eleventh graders found drug use to have lowered in town. Proof that STEPS is making progress.
Also, there's no denying that on a whole the restaurant business is down 10-15 per cent, so the cards are only proving a good thing in the community all around.
Ninth grader and youth council member Trever Rogers says it took a couple of meetings to choose the questions, but the extra planning was worth it.
"We wanted to get families to talk. So, when we went through the cards we thought would work, then sorted them again and picked out the ones we really thought would work. We got an email from a mother whose family stayed at Mo's for two hours, claims the cards helped her connect with her kids in ways she hadn't in a long time. After they finished eating they opened up the box and started reading the questions to her kids. She said she and her husband had a great time listening the responses from her kids."
What's next for the conversation card initiative?
"There have been so many requests for a home edition." Justine says. "We're going to create a whole new set of questions. Even if parents took them home and didn't use them they'd still have the desire in the back of their heads. Even if they use them once a month, or once a year, they will still have access to them."
Trever says, "My mom, years ago, had a deck of cards for conversations. She brought them out at holidays and birthdays extended family, and they were great, because you don't see your extended family for so long."
For more info, go to southingtonsteps.org.


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Best Mediterranean Cruise Ports
Tsambika Beach has the right amount of people and services in Rhodes. --Photo by David Dickstein
Dancers welcome cruisers at the port of Rhodes. --Photo by David Dickstein
(Third of three parts)
Picking out just 10 favorite Mediterranean ports is like choosing only a pound of chocolates at See's Candies. They're all so marvelous, orange cream and Marseilles excluded.
We've covered Rome, Athens, Naples, Barcelona, Florence and Santorini, in that order, and now it's time to round things out. So, without further ado, here's Nos. 6-10 as discovered during back-to-back 10-day Mediterranean cruises aboard the resplendent Celebrity Reflection and remarkable Carnival Vista.
#7: Rhodes
What does the Grecian port of Rhodes have in common with Disneyland? Walk off the ship or through the turnstile and in 5 minutes you can enter a castle-like fortress where fun, food and souvenirs await. Just don't expect to see Mickey Mouse in Rhodes – hungry feral cats abound within the 2 1/2 miles of 40-foot-thick medieval walls. Look passed the cafes serving pizza and spas where "doctor fish" nibble on the dead skin of tourists' feet, and Rhodes' Old Town resembles a bona fide Turkish bazaar – and for good reason: Turkey is just 11 miles away and bound by 300 years of influence.
Exploring Old Town can easily be done on your own and minutes off the boat, but getting to the second-most visited attraction in Rhodes – the beautiful, yet tourist-jammed ancient city of Lindos – requires ample time and wheels since the 35-mile trek each way takes about 45 minutes, longer during peak season that runs April through September. Crowds will also have you deciding whether the Acropolis, site of a temple to the goddess Athena, is worth hiking up a narrow and sometimes thronged and treacherous path. Donkeys can carry you up in exchange for 5 euros and your PETA membership card.
Rhodes is known for its collection of stunning beaches and shapely sun worshippers, so if taking a dip in hot Greece sounds good, avoid built-up Faliraki Beach if you have the time to go farther south to a less-congested shore. Located halfway between the ship and Lindos is Tsambika Beach, which has just enough tavernas serving grub and grog, free Wi-Fi, and lounge chairs, umbrellas and aquatic equipment for rent. The southern end is more serene and where nudists laugh in the face of melanoma.
If visiting Tsambika Beach, Lindos and Old Town sounds like a perfect day, which it was on my return trip there, do it in that order so you're among the first ones at the ocean, and book a private driver before leaving home. Highly recommended is Taxi Rhodes, which charged 180 euros for 6 hours that began at 9 a.m. sharp dockside and ended with a sas efcharistó and antio – thank you and goodbye – just outside Old Town where we took it from there. Manolis Kiaourtzis couldn't have been a better and more intuitive driver, guide and representative of this top Mediterranean port.
#8: Kusadasi
One could easily spend the entire day within walking distance of the ship in Kusadasi, Turkey. The port's vibrant and secure shopping center and adjacent retailers are chockablock with such local specialties as carpets, silk pashmina and ceramics. If you're ever tempted to skip a pre-paid lunch on the ship, this is the place. It's hard to beat hospitable Guverte Restaurant for seafood (try the grouper), coffee (Turkish, of course) and Facebook-worthy photos of your floating hotel from across the marina.
But let's talk Turkey: Cruise ships don't call on Kusadasi because of what's in and around the port. The emphasis here is Ephesus. Once home to philosophers, gladiators and rulers, the ancient city is rich in ruinous architecture and history, and a fleet of buses parked on the other side of the gangway can take you there in 30 minutes. Nearly every shore excursion offered through the cruise lines includes a visit to what's considered one of the world's most magnificent and best-preserved archaeological sites. There's usually a no-frills 3 1/2-hour-long tour to appease your inner Clark Griswold (think Grand Canyon), and a few with durations of over 8 hours for those wishing to immerse themselves in the Greek Dark Ages to Late Middle Ages of 10th century BC to 15th century AD. Longer tours often include a visit to the House of the Virgin Mary, where the blessed mother of Jesus is reputed to have spent her final years of life. The less devout and gullible will likely deem this add-on a tourist trap. Cynics also may be turned off to the obligatory carpet demonstration that's usually tacked onto a ship-booked tour. But don't make a dash for the exit too quickly; learning about traditional hand-made rugs is actually pretty cool if you ignore the high-pressure sales tactics. If nothing else, enjoy the free apple tea.
#9: Mykonos
A dearth of shore excursion options is actually part of the allure of this Greek island, a destination Lonely Planet keenly observed as one that "flaunts its sizzling St. Tropez-meets-Ibiza style and party-hard reputation." Any nightlife will have begun long after it's anchors aweigh for you since larger cruise ships are gone by sundown, but a hip vibe permeates even in daytime, as does traditional Greek charm.
Tours of ancient Delos, birthplace of the god Apollo, and shuttles to wonderful beaches get some takers, but most visitors who get off the boat hoof it to Old Town to stroll the narrow streets that lead to boutiques, museums, cafes, pastry shops, churches and a few surprises. Many get flat-out lost thanks to a centuries-old defense scheme designed to thwart would-be invaders. The town is plotted as a maze, and a total whitewash of its buildings plus a street system that would delight Sarah Winchester make navigation challenging even for tourists with GPS. Not to worry – the Aegean Sea or a friendly local will stop you from going too astray.
#10: Crete
First impressions of Crete being a loser port are understandable, especially if judging by high Mediterranean standards. Heck, even the cruise lines' list of shore excursions is mediocre for a place where Hercules once roamed. To this point, the "Best of Crete" tour is highlighted by a visit to the Palace of Knossos that disappoints for being overly restored and lacking in original antiquities. But give the home to Europe's earliest civilization a chance, because the ho-hum-sounding tours give you a rare, stress-free opportunity to assimilate with the locals.
There's no easier, cheaper or quicker way to do that than taking the hop-on hop-off open-top busses of Heraklion Sightseeing Tours. For just 20 euros (15 if you buy online in advance or cut a deal with the ticket seller), you're taken on a loop around Crete's capital and Greece's fourth-largest city. Any of the 11 stops is a starting and ending point, technically, but the official one is just off the ship. After quick stops by a medieval fortress and a small, but decent aquarium, consider getting off to truly soak up indigenous culture and color. Pop in a grocery store, where the most unusual items are often in the produce and meat sections. Check out the butcher's skinned rabbit destined for a Greek stew called stifado. Like dinner, if you're not in a hopping mood simply stay on the bus and enjoy the multilingual recorded narration uninterrupted; you'll be back to the ship in an hour.
If You Go
Carnival Cruises, www.carnival.com
Celebrity Cruises, www.celebritycruises.com
Taxi Rhodes, www.taxi-rhodes.com
Heraklion Sightseeing Tour, www.her-openbus.gr


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|The Horse Race charts the presidential election campaign using two measures: the Iowa Electronic Markets, and our own index of pundit opinion. The Iowa Electronic Markets are a project of the University of Iowa College of Business administration. They are real markets, with shares that pay out after the election. We follow Iowa's Winner-Takes-All market, which will pay $1 for each share in the winner. (Thus WTA share prices reflect the market's judgment, at any moment, of the chance of a candidate winning.) The Iowa folks' thesis is that markets are better prognosticators than the pundits. You be the judge. For more information, or to invest, visit the Iowa Electronic Markets site.
The Iowa Markets also track the battle for control of Congress. See below .
|Clinton: 88.5, 0.9 from yesterday Dole: 11.7, 0.3 from yesterday
|Clinton: 93, 1 from last week Dole: 7, 1 from last week Perot: Zero. Can we agree on that?
Having sold out their anti-mudslinging moral posture for a nastier and more exciting contest, the pundits found themselves with neither. The low road at this point would have been to lash out at Dole out of shame, since Dole and Kemp had proven themselves more honorable than their moral judges in the pundit class. The even lower road, which the pundits took instead, was to lack any sense of shame and to assert that Dole, not they, should be ashamed by his failure to meet the only standard that really counts: doing whatever it takes to win.
No flip-flop by Dole or Clinton has been as spectacular as the pundits' about-face on the propriety of negative campaigning. Ted Koppel reminded his fellow critics of negativism: "Be careful what you wish for--you may get it." Legions of commentators declared civility a political vice. "Let's bring back acrimony!" pleaded the Weekly Standard's Tucker Carlson. Maureen Dowd longed openly for the exquisitely nasty Dole of 1988. R.W. Apple defended the New York Times' scant election coverage by dismissing the race as "boring." Sam Donaldson admonished the Dole camp: "To sit back and say, 'Well, we're just going to sit here and talk issues,' is the road to defeat."
The negativism debate segued gracefully into a discussion of Dole's legacy and burial arrangements. In Thursday's Nightline interview, Ted Koppel suggested that Dole might prefer to "lose as a gentleman," and Dole replied, "Whatever happens, I want to be at peace with myself when it's over." Friday's New York Times spoke of Dole's "place in history" as an honorable loser alongside Walter Mondale. Terminal-diagnosis code word of the week: "dignity." Chat shows trumpeted the covers of Newsweek ("Is It Over?") and the Weekly Standard ("Can We Get This Election Over With Already?"). Conservatives mustered no confidence that the new Clinton scandal (involving campaign money from Indonesian businessmen) would attract attention or change people's votes.
The VP debate: The pre-debate hype was that Gore and Kemp would relieve the boredom of 1996 by supplying a foretaste of a rip-roaring presidential contest in 2000. The post-debate lament was that Gore and Kemp would multiply the next four weeks of boredom into four more years of the same. Gore was declared robotic, but Kemp was declared incoherent and therefore the loser. Pundits consoled themselves with the hope that Kemp's performance was bad enough to cost him the nomination in 2000 and spare them the attendant boredom. The New York Times called it "an earnest wonkfest." Half-cynics said the debate wouldn't change any votes. Total cynics said it wouldn't have changed votes even if it had been lively, since nobody cares about the vice presidency. The juiciest topic of discussion was the Dole camp's anger at Kemp for failing to do Dole's dirty work--thereby forcing Dole to do it himself.
Recriminations: "Let Republicans begin their recriminations," decreed George Will, as the traditional post-election bloodbath within the losing party commenced a month early. Pundits are delighted that Dole is being usurped as party leader (by Kemp and campaign vice chairman Bill Bennett) and bad-mouthed by anonymous Republicans and his own aides, while Dole loyalists are firing back at Republican critics (calling Bill Kristol the "first rat"), allies (threatening to boot Bennett off the campaign), and congressional Republicans (for collaborating with Clinton at Dole's expense).
Congress: This week's analysis pieces focused on organized labor's ads against Republican candidates in swing districts. Paul Gigot faulted GOP chairman Haley Barbour for hoarding the party's money instead of challenging the labor ads: The New York Times' Adam Clymer reported widespread damage to Republicans from the ads and quoted various projections: a) Speaker Gingrich's estimate of the Democrats' takeover odds at 5-1 (up from 10-1); b) congressional archpundit Charlie Cook's prediction that the parties will end up fewer than 10 seats apart in the House; and c) a calculation by "academic experts" that a double-digit win for Clinton would probably give the Democrats a House majority.
--William Saletan
Iowa Electronic Market: Congressional Control Gain is a share that pays $1 if the Republicans increase their number of seats. Hold pays $1 if they stay the same or lose seats but retain majority control. Lose pays $1 if the Republicans lose their majority. The IEM site has graphs tracking price changes over time for the House and the Senate. The latest prices as of 10/18/96:
|Senate Gain: 24.0, 0.7 from yesterday Senate Hold: 60.8, 1.3 from yesterday Senate Lose: 17.1, 0.5 from yesterday
House Gain: 9.0, 0.8 from yesterday House Hold: 62.1, 0.2 from yesterday House Lose: 29.9, 1 from yesterday
Congressional Pundits' Index: as of 10/14/96
|Senate Gain: 15, 3 from last week Senate Hold: 63, 2 from last week Senate Lose: 22, 1 from last week
House Gain: 3, 1 from last week House Hold: 67, 3 from last week House Lose: 30, 4 from last week


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Harry does not approve
May 20, 2011
Sorry to all of you H/Hr shippers, but this winning caption was just too good to pass up. Congratulations to Leaky user gryffindor31! You also win 100 MyLeaky points.
We had a ton of great submission this week, so be sure you check our Tumblr to see more! The next picture we've selected for you to caption (by the way, all of our screencaps are from our wonderful galleries!) can be seen at the top of this post. As always, leave your best captions in the comments and check back here for the next winner. Good luck – and congratulations, again, to gryffindor31!


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A Rocky Road for Nucleotide Analogs
Nucleotide Analogs' Toxic Side Effects
Gilead Science has been developing a class of broad-spectrum antiviral agents called nucleotide analogs for over five years. To date, cidofovir (Vistide) has been approved for the treatment of AIDS-related CMV retinitis and adefovir (Preveon) is in an expanded access program for the treatment of HIV. Both compounds have proven antiviral activity and long half-lives in the body, which allow for less-frequent dosing. Unfortunately, both compounds are also associated with the development of potentially serious side effects, including damage to the kidneys.
More Problems with Cidofovir
Continuing reports of adverse events associated with cidofovir use prompted Gilead to distribute a letter to health care providers and community members in August, reinforcing the importance of following strict treatment guidelines when administering the drug. Cases of acute renal failure resulting in dialysis and/or contributing to death have occurred after as few as one to two doses of cidofovir. Anyone with impaired renal function should not receive the drug. Patients should avoid other agents with nephrotoxic (kidney-damaging) potential, such as foscarnet.
Intravenous hydration with at least one liter of saline solution should be administered prior to each infusion of cidofovir. Three doses of oral probenecid must be administered the day of the infusion. (Probenecid is a drug that prevents the kidneys from absorbing the cidofovir.) Renal function must be monitored 48 hours prior to every dose. In the event that serum creatinine and urine protein levels are elevated, cidofovir dosing should be reduced or discontinued. If all of these guideline are rigorously followed each time the drug is administered, the risk of renal toxicity is reduced.
In addition to the high incidence of kidney problems, a higher rate of uveitis (inflammation of the eye) has been reported than had been anticipated based upon clinical trial experience. The rate of eye inflammation was under 5% in trial participants, but since the drug was approved, ophthalmologists from three university clinics have reported rates of 50% in patients receiving cidofovir therapy for 125 days (JL Davis et al. Archives of Ophthalmology. June 1997; 115(6):733-7). Patients with more advanced CMV disease are more prone to uveitis.
Any eye inflammation after an infusion should be reported to the ophthalmologist immediately, as continued dosing with full-strength cidofovir can exacerbate the situation. Uveitis can lead to scarring and loss of sight. Although it can be treated with topical steroids, there is a risk for the development of cataracts. Hypotony, a serious condition of reduced pressure in the eyeball, can also occur, so intraocular pressure should be monitored.
Finally, three cases of hearing loss associated with cidofovir have been reported. Upon discontinuation of therapy, the hearing impairment abated. Janet Davis, M.D., of the University of Miami, summed things up by stating, "I think cidofovir is an excellent drug -- it works for the retinitis -- but it is very, very toxic. It has to be treated with extreme respect."
Adefovir Dosing: How Low Can You Go?
The development of renal toxicity has been associated with the use of Gilead's other nucleotide analog, the anti-HIV agent, adefovir. While the onset of kidney problems is very rapid with cidofovir, it is much more gradual, and thus far less severe, with adefovir. As TI reported in April, 40% of people on the 120 mg/day adefovir dose for over six months were developing signs of incipient kidney tube damage ("Fanconi-like" syndrome -- see Treatment Issues, April 1998). Gilead has recently amended its expanded access program to include dose reductions. Under the revised protocol, newly enrolled patients will be randomized to either 60 mg or 120 mg doses. All patients receiving 120 mg will have their dose reduced to 60 mg after 16 weeks of treatment. Patients receiving 60 mg of adefovir who experience treatment-related adverse events will have the option to either permanently discontinue treatment or reduce the dose to 30 mg daily.
There is only preliminary data to support the efficacy of the 60 mg dose and none to support the 30 mg dose. The data available on 60 mg comes from Protocol 417, which compares doses of 60 mg and 120 mg in combination with other antiretroviral agents, including protease inhibitors. Since the study is still ongoing, investigators do not know which dose participants are taking. After 20 weeks of therapy, efficacy results are comparable between the two groups, but the potent antiviral effect of the protease inhibitors might obscure any impact from either dose of adefovir. One dose level does appear to be better tolerated with respect to renal toxicities. Gilead is betting that this is the 60 mg dose.
Monthly lab tests are required to monitor creatinine, electrolytes, liver function, urine protein and glucose. It remains to be seen whether Gilead can find a dose of adefovir that is both potent and well tolerated. Until then, patients will have to decide whether the benefits of adefovir, especially at lower doses, are worth the potential toxicities.
As TI went to press, Gilead announced that the large CPCRA 039-adefovir protocol was terminated by the trial's Data and Safety Monitoring Board. Safety concerns did not trigger this decision. Rather, 039 was unable to accrue enough participants to answer its primary question: is there a survival benefit for the adefovir group? The study was not designed to look at virologic markers (changes in viral load, percent below detection) as the main proof of the drug's impact. In fact, the data that were collected indicated no differences between 120 mg of adefovir and placebo on HIV viral load. Adefovir's relatively moderate antiviral effect would have been obscured in any case since participants were permitted to change their other drugs at will.
Adefovir for AZT/3TC Users
A major remaining question is whether there are subpopulations that can obtain enhanced benefit from adefovir. A genotypic substudy was conducted on 142 participants from Protocol 408 -- Gilead's pivotal trial that supplemented participants' existing therapy with adefovir or placebo for 24 weeks. Mean baseline viral load was 25,120 copies/ml. Results of the substudy were reported this summer at the 2nd International Workshop on HIV Drug Resistance and Treatment Strategies in Italy.
Participants were broken down by baseline genotypic resistance mutations. Between 70% and 90% had previously used 3TC and over 90% had previously used AZT for an average of three years. In this heavily pretreated group, 76% at baseline had the codon 184 mutation associated with 3TC resistance. All participants in the substudy continued using 3TC in their regimens. The participants with the 184 mutation alone achieved a 0.94 log (88%) decrease in viral load at week 24. Participants with the 184 mutation plus high-level AZT resistance (as defined by mutations at codons 41 and 215) experienced a 0.51 log (69%) reduction in viral load. Confirming that adefovir is ineffective against AZT-resistant HIV, the worse antiretroviral response, an average 0.05 log (11%) reduction, was seen in participants with high-level AZT resistance without the 184 mutation. (The few study participants with none of these mutations experienced a 0.65 log (78%) viral load reduction.)
The addition of the 184 mutation seems to increase HIV's sensitivity to adefovir, although the durability of this effect is unknown because of HIV's propensity to develop further compensating mutations. Still, Gilead may position adefovir as salvage therapy for the large AZT/3TC experienced population with few other treatment options. Although the viral load reductions are not huge in this group, they are better than the 0.39 log (59%) reductions seen by the 408 cohort as a whole. Choosing a drug based on the presence of specific resistance mutations is a novel concept, but as more is learned about the significance of genotyping, this may become a useful means for tailoring treatment regimens.


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Some common efforts to save actually result in wasting money. Think twice and avoid these common pitfalls.
From spend-happy friends to bad bulk buying and more, these sneaky costs and poor financial habits could be sucking the life out of your bank account.
As you continue to work a full-time job, wrangle the kids, and make your money work for you, there are some sacrifices that you are making every day and you may not even realize it
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Tracheotomy: Airway Management, Communication, and Swallowing
Eugene N. Myers, Jonas T. Johnson, Thomas Murry
Singular Publishing Group, 1998 - Medical - 172 pages
This is a comprehensive, well-illustrated reference on classical tracheotomy in adults and children. It provides professionals with the essential tools needed to support safe, effective intervention in inpatient and outpatient settings and addresses special populations and their unique needs.
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Technique and Complications of Tracheotomy in Adults
Technique and Complications of Tracheotomy in the Pediatric
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airflow airway obstruction aspiration assessment bedside bleeding breathing bronchoscope catheter cheal cheotomy Chest closure communication complications connuld cough cricoid cartilage cricothyroidotomy cuff deflation cuffed Cuffless decannulation dilator dysphagia electrolarynx endoscopic endotracheal intubation endotracheal tube fenestrated fistula glottic granulomas incision infection inflated cuff injury inner cannula innominate artery inserted Kazandjian laryngeal long-term mechanical ventilation minimize monitoring morbidly obese neck plate nursing obese patients obturator occur one-way operating room oral OSAS patients ostomy Otolaryngology outer cannula oxygen Passy-Muir pediatric percutaneous performed phonation placed placement pneumomediastinum pneumothorax postoperative preoperative prevent procedure pulmonary removed require respiratory risk secretions skin sleep apnea speaking valve speech speech-language stenosis stoma subcutaneous subglottic suctioning Surg surgeon surgery surgical swallowing syndrome technique tient tion tolerate tomy tomy tube trache trachea tracheal ring tracheal wall tracheostomy tube tract traction sutures treatment upper airway ventilator-dependent vocal folds voice wound


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Note: This page is very old and does not apply to at all to the current state of KDE software.
Java support for KDE is now fairly significant. You can add applet support to your KDE applications, and with the Qt/KDE Java bindings you can develop KDE apps in Java. Issues relating to Java support for KDE should be discussed on the kde-java mailing list (though applet issues are usually discussed on kfm-devel).


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Budget holidays with the best views in the South Island
See more and spend less on a motorhome holiday in the South Island
You can never underestimate the experience of travelling at your own pace, stopping where you love the views the most. New Zealand's South Island is jam packed with amazing views, lookouts, sunrises and sunset panoramas. Get your camera, grab a cost-effective campervan or motorhome from Cheapa Campa and set out on a budget holiday to capture the best views.
From Christchurch, head east and spend a few days at Banks Peninsula. With hike trails ranging from two to four days, you'll be walking over a volcanic crater rim surrounding Akoroa Harbour, through native forest and along clifftops, sandy beaches and open pasture.
Driving north, you'll soon hit the tip of the South Island, the Marlborough region, where watching sunset with a bottle of locally produced Sauvignon Blanc is an unbeatable experience. Enjoy it from the Oyster Bay Vineyard, with the majestic Richmond Ranges as your backdrop.
Coming around the top of the South Island, you can't beat a few nights at Abel Tasman National Park. Totaranui campground offers access to golden sands and clear waters of Totaruanui beach – a perfect spot for a magical sunrise walk.
From blue ocean to snowy mountains – the Southern Alps are one of New Zealand's most amazing views and an absolute must do on the South Island. Take a scenic helicopter flight and soar above this incredible landscape.


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Published March 17, 2005, in issue 0411 of the Hook
Funding for arts education isn't a problem in Europe the way it is here, so The Chorus (Les Choristes), which makes a strong case for it, should be considered a gift to us from nos amis, the French.
The closest American equivalent, Music of the Heart, got mired in sentimental clichés. So does The Chorus, but clichés seem more natural in French, cliché being a French word.
This is another in the sub-genre of Educators Who Made a Difference movies. It opened against Coach Carter in New York to show sports can clobber the arts at the box office.
The story is set in 1949 but framed by a reunion of two former schoolmates 50 years later. Pepinot (Didier Flamand) brings to Pierre Morhange (Jacques Perrin), "the world's greatest conductor," a journal kept by Clément Mathieu (Gérard Jugnot), their teacher in that pivotal year.
The boys are students at a "boarding school for difficult children," Fond de l'Etang (Rock Bottom– how symbolic can you get?), ruled by the heavy hand of Principal Rachin (François Berléand). His policy is "Action...Reaction," meaning squelch possible trouble at the first sign, usually by overreacting. If the boys weren't discipline problems before they came to the school, they are now.
Mathieu believes they just need a little T.L.C. and Do Re Mi. A failed musician who had despaired of ever working in that field again, he's inspired by the boys' response to his effort to start a choir.
Rachin is another story. His favorite word is "Silence!" and singing doesn't go with that. (Even though the school wouldn't attract la crème de la crème, he's too much of an idiot to be believed.)
Few of the boys have much individual talent, but Mathieu makes them sound good collectively. The diva who emerges is Morhange (Jean-Baptiste Maunier), who has an angelic face and a voice to match but is troubled by jealousy over the way men (including Mathieu) and boys alike react to his single mother, Violette (Marie Bunel).
Just when Mathieu appears to have tamed the minor miscreants, a major hardcase, Mondain (Grégory Gatignol), is thrown into the school to cause new disruption.
The conflicts come across as contrived in the script, co-written by director Christophe Barratier, but at least we're spared a climactic competition in which the boys win the Choral Olympics or something. The closest The Chorus comes to that is a recital in which the boys sing for a countess (Carole Weiss) who's the school's benefactress.
Good acting, good music, and the good feeling it leaves you with more than compensate for a lack of credibility in The Chorus. It whistles a happy tune.


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A HUGE thanks to Amanda for helping me paint the outside of the Inn by the Hotchkiss Room! When the house was painted last fall there was a climbing hydrangea on a trellis that covered the wall. This spring my landscaper took the trellis down and removed the plant. Painting that last bit of the Inn has been on my list of things to do for what seems like forever. Today, I get to check it off.
I feel so very fortunate to have the staff working with me that I do. I couldn't do this without them… Amanda, Kristen, Juli, Judy, Donna and Carson. And even though technically she doesn't work with us anymore… Audrey. Thanks Ladies!


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Heavy funk-metal outfit and multi-platinum rock band, [lastfm link_type="artist_info"]Incubus[/lastfm], have essentially achieved the dreams of many an aspirant teenage rocker. Forming in Calabasas, California, Incubus rapidly graduated from high school hopefuls to one of the biggest rock bands in the world.
With their seventh studio album, If Not Now, When?, set to be released on July 12th, Incubus has a sixteen year sonic retrospective of incredibly long-lasting and widespread radio singles.
To stimulate your musical memory, we've put together a list of Incubus' Biggest Career Hits. Hopefully, we'll get to rock out to some of them during their free streaming performance on Live on Letterman at the Ed Sullivan Theater on July 11th, 9pm Eastern (6pm Pacific).
You can watch it right here or on CBS.com.
From Fungus Amongus (November 1, 1995 / November 7, 2000):
"Take Me To Your Leader"


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If you're using continuous light sources for your portrait photographs—tungsten lighting, or daylight-balanced fluorescent lights, for example—then controlling how much power they output will depend entirely on the specific lighting model. Some will allow you to vary the output, perhaps by illuminating fewer tubes in a fluorescent lightbank to reduce the intensity, while others might not have any control, so moving them closer to or further from the subject will be the only way that you can control the light.
With flash lighting, however, there is often much greater control over the power output. Studio strobes may offer a range from full power down to an output of 1/32 (or lower) of their maximum strength. In a confined studio space, being able to control the flash output in this way is particularly beneficial, as it means you can get the look you want from your lights, as well as the intensity of light you need to shoot at your chosen aperture. In this section we'll look at just how simply changing the output of your lights can transform your lighting setups.
When you are using two lights at different power settings, you basically have one main light source (your "key" light) that is providing the overall illumination, and a second ("fill") light that is there to lighten shadows. As you saw earlier, a low-cost alternative to a fill light is a reflector.
With the main light set at full power, directly in front of the subject, and the fill light at a 60-degree angle, outputting two stops less light, the left side of the model's face is subtly lighter than the right side, preventing the portrait from looking overly flat.
Both lights have been positioned at a 30-degree angle, but the main light to the left of the camera is two stops brighter than the fill light to the right. The different power settings avoid the face being evenly lit.
In this setup, the main light is close to the camera, with the fill light coming in from a 60-degree angle. This gently lightens the shadows that would otherwise be caused if you were using a single light.
As the main light is moved further away from the camera, the effect of the fill light is made more apparent as it illuminates the left side of the model's face and prevents it falling into heavy shadow. This is especially effective when the subject is against a dark background.
In this symmetrical setup, both lights are coming from a 60-degree angle, but the weaker output of the fill prevents the lighting arrangement from creating an overly flat image. The contrast between the two sides of the face creates a distinct three-dimensional look.
With the main light at a 90-degree angle to the camera, it largely illuminates the side of the model's face and nose. The weaker fill light (set at two stops less power than the main light) lifts the shadows sufficiently to reveal the subject's facial features, even against a dark background.
If you compare this setup to that on pages 112–113 (where the lights are in identical positions), you can see how using two lights at different strengths can create an entirely different look: where the previous setup delivers a bright, relatively evenly lit portrait, here the look is more sculptural.
As you have seen previously, two opposing lights set either side of the subject will invariably produce a shaded band down the center of your subject's face. Limiting the power of one of the lamps also darkens one side of the face, reducing the symmetry of the lighting.
Compare this setup to that shown on pages 218–219. The lights are in identical positions, but in this arrangement the power of the fill light has been reduced, so it is now four stops lower than the main light. The shadows are still lifted, but the overall contrast in the face is heightened.
Again, the fill light is set at four stops less than the main light, meaning the shadow areas created by the main light, although filled, remain fairly dark. Increasing the contrast between the two lights is especially effective when you're shooting black and white.
Although the fill light is set four stops lower than the main light, its angle to the subject still produces a bright catchlight in the model's darker (left) eye. The less-powerful fill also creates some much-needed contrast in what would otherwise be an evenly lit portrait.
Another symmetrical lighting setup, but two lights set to output different power settings avoid the mirrored lighting effect seen on pages 114–115. However, the distinct shadows around the eyes and cheeks created by the opposed lights remains, as does the dark central "stripe."


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The next version of Microsoft's Windows Phone operating system has arrived early for those willing to risk a slapdown by Redmond.
A version of the code built by Microsoft and delivered to smartphone-makers this summer has apparently slipped free of the Redmond-OEM loop and was leaked online.
The leaked code is build number 7720 of Windows Phone 7.5, which Microsoft signed off and released to phone-makers in July.
A link to the code, better known by its codename of Mango, appeared in the XDA Developers forums here, larded with plenty of warnings.
The post points out this is vanilla MS phone code, missing the tweaks that phone-makers will add to differentiate their phones from those of the competition.
What the post doesn't say, but probably should, is that if you decide to install 7720 on your phone you run the strong chance incurring Microsoft's displeasure.
You might also miss out on future updates once Microsoft and the OEMs officially ship phones loaded with Windows Phone 7.5.
Earlier this year, many users keen to get their hands on the highly anticipated but delayed NoDo release of Windows Phone 7 downloaded the ChevronWP7 hack, created by Chris Walsh, which let them unlock Windows Phone devices and install an unfinished build of NoDo.
Microsoft initially warned against using such home-brew installations, saying it was not sure what would happen to people's phones once the hack was used. As it turned out, people who installed the unofficial update were not able to move to the finished NoDo.
After NoDo was made available, Microsoft took great pleasure in crowing "I told you so" in an official company blog post here.
Read More : theregister.co.uk


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Wow, powerful words yes? I could only imagine an article like that in the news or on T.V. Would be interesting for sure. Yes, yes, that was click bait. We all have come to know it sometimes well. But wait! Don't leave yet, read on to hear a little on this topic still.
Yes, I make adult content. Mostly just images of IMVU models. Images I find rather fun to make at times. Like a mouse is my pencil. ^^ It can be easily viewable in a few easy to find places, but I will not advertise here in this article. My point is this. My stuff is fairly tame for what's easily searchable on the internet. Every age can access it too. Maybe you found this article from a site that's sole purpose is dedicated to a game called IMVU. Other sites as well people use and associate with IMVU and their life there. But is it decent content for someone under the age of 18? Well, I think not, that's why I am putting together this article.
Let's look at steps you might be able to take, to keep those not suitable images a little harder to view. That's right, adult settings. I use a Windows computer, and I know it has them. I have no children though, so I never used them. I think you have them as well. We should check.
Please read, browse, or take in the fact, that it's about Parental Controls on a personal computer. Then I will meet you back here, once you have done that.
https://www.howtogeek.com/howto/10524/h ... windows-7/
Wow okay, so what I see there is I can set a lot of stuff up. That's just on Windows 7. Imagine what a Mac has. I don't know I don't own one, but I bet it's easy to find like it was for Windows 7. Even Windows XP had stuff like this. Now imagine what you could block from under 18-year-olds with these options, on an Android smartphone or tablet.
We may never see a really really good article titled "The DANGER!!! of ADULT CONTENT!!!" Heck, maybe there already is an article on that somewhere. I never had to check. What about you?
Imagine if you knew about this website here, called StaySafeOnline.org
https://staysafeonline.org/stay-safe-on ... l-controls
Are you not yet 18 years old? I think you should talk to your parents about this post here. See what they have to say about it, I know for sure, that would make them really really happy too. Like, they might get you ice cream, or even a new iPhone. Haha, that would be awesome, eh?
Your humble internet neighbor,
The DANGER!!! of ADULT CONTENT!!!
Calling All IMVU Graphic Artists! Here is a place for you to share your talents, hang out and call home!
Post Reply
2 posts • Page 1 of 1
- MandaMarie
- Pixel Princess
- Posts: 233
- Joined: Sun Feb 26, 2017 3:09 pm
- Location: West coast USA
- IMVU Homepage: http://avatars.imvu.com/MandaMarie
- Contact:
- MandaMarie
- Pixel Princess
- Posts: 233
- Joined: Sun Feb 26, 2017 3:09 pm
- Location: West coast USA
- IMVU Homepage: http://avatars.imvu.com/MandaMarie
- Contact:
Re: The DANGER!!! of ADULT CONTENT!!!
*placemark for article two.*
Post Reply
2 posts • Page 1 of 1


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Student Handbook
The Bowdoin College Student Handbook is web-based. We hope you'll find the information within accessible, useful, and easy to navigate. Our office urges you to take some time at the beginning of the year to read and familiarize yourself with the information this Handbook contains. This is important for all students to do every year, as some policies may have changed since last year.
The Handbook is your key reference to the policies, procedures, and governance structure of the College. It is your responsibility to be familiar with College policies published within this Handbook and the Bowdoin College Academic Handbook and for abiding by the rules and regulations described. As a web-based Student Handbook, this is a dynamic document with links to various College departments, resources, programs, and services. Some information will change over the course of the year as departments and programs update their sites. While the information contained within the College Policy section is unlikely to change, the College reserves the right to make modifications or changes during the academic year as it deems necessary and appropriate; any such changes would be brought to your attention.
The Handbook is a resource that exists to assist you in planning, navigating, and—importantly—contributing to the future policies and directions of your College. As is described in the section on College Governance, students are full members of virtually all faculty, College, and trustee committees, and those committees develop the policies of the College. Compared to many other colleges, Bowdoin has an unusually high level of student representation at all levels of governance, and the opportunity to serve and participate can be powerfully educational and meaningful.
Whether you are new to Bowdoin or a returning upperclass student, we encourage you to reflect on the coming year and determine what it is that you would like to accomplish within and beyond the classroom. You may never again find yourself at a time or place in your life that offers such a wonderful opportunity for growth. But to ensure this growth, you'll need to challenge yourself. Toward that end, we urge you: resist that which is familiar and comfortable to you. You will determine whether these are "the best four years of your life." Our office hopes that you use your time here to establish a personal standard of intellectual engagement, community involvement and leadership, rich and diverse friendships, and the enjoyment of "generous enthusiasms" that you will sustain and build upon throughout your life.
Our entire office wishes you every success at Bowdoin and stand by to support and to challenge you as you take full advantage of this extraordinary place.
Best wishes for a successful year!
The Dean of Students Office


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*Get extra protection from data loss with HP ProtectSmart Hard Drive Protection.*Make a statement with an elegant design wrapped in luxurious bronze and chrome HP Intersect Imprint finish.*Project lustrous sophistication with HP Intersect Imprint finish in bronze.*Create personalized, silkscreen-quality DVD and CD labels with LightScribe.*Chat face-to-face or capture video clips using the HP Webcam and integrated microphone.*Enjoy the ultimate audio entertainment experience with SRS Premium Sound.
UNSURPASSED STYLEExpanding on the sophisticated elegance of the current line, the new dv series is defined by fluid, modern lines and metalized finishes with surprising innovations inside and out. The dv5 series Intersect Imprint features an argyle like pattern for subtle contrast to the liquid appearance of the metallic finish. And touch media controls light up and become visible only when the system is powered on further enhancing the clean appearance. HP's mobile products have won coveted International Red Dot, iF and CES Innovation design awards and been recognized by other leading design institutions.
MOBILE ENTERTAINMENTProviding more choices than ever, HP MediaSmart enables access to DVDs, videos, photos, music, games, Internet TV, and streamed or recorded TV (with an optional TV Tuner at the touch of a button. Built-in demos show you how to add music to your slide shows or videos with drag-and-drop functionality -and much more. An HDMI port enables you to watch films on an HD TV. Muvee Reveal makes creating films complete with effects and transitions a snap! Extras include dual headphone jacks and an HP Mobile Remote Control. It's time to play!
DESIGNED FOR YOUR LIFEFor those who want digital entertainment features and the latest mobile technologies in a stunning design that balances performance and mobility, the HP Pavilion dv5 series Entertainment Notebook PC delivers! Its elegant Intersect Imprint finish helps protect your system. HP Pavilion notebook PCs help you work faster, connect in new ways and play more.- Connect with the HP Webcam. Turn your next instant message into a live video chat with the integrated webcam, omni directional microphone and an IM solution. Optimized for low-light environments, it's great for capturing short videos to share on your favorite social networking site. Personalize your videos with included YouCam software from Cyberlink.- Enhanced security with hard drive protection. HP ProtectSmart Hard Drive Protection locks your hard drive into place when it senses abrupt motion to help prevent data loss. The built-in eSATA/USB Combo port enables fast backup to an external hard drive.- Personalized disc labels with LightScribe. Create custom laser etched disc labels right in the drive with LightScribe and preinstalled Cyberlink DVD Suite. Just burn data on the disc, flip it over and burn the cover image using any scanned image and/or text. Visit the LightScribe Web site for more information.-Photo-ready with 5-in-1 media card reader. Transfer photos from your digital camera in seconds.-Full-memory access. Windows Vista(1) 64-bit operating systems are able to fully access system memory to support 3D games and complex applications.
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Service Banker - Tehachapi
What sets Bank of the West apart from other banks is our team members–they embody the optimistic spirit of the West. There is a spirit here that drives us to do more. Our team of more than 10,000 employees is vital to the success of our Bank. They reflect our modern western values—straightforward, entrepreneurial and optimistic. We seek to create a corporate culture that fosters and rewards excellence, encourages creative thinking and respects diversity – an environment where team members are engaged, supportive of one another and enthusiastic about serving our customers. Bank of the West offers the stability of a company that has a 135 year history and is part of BNP Paribas, a European leader in global banking and financial services and one of the 6 strongest banks in the world. We offer opportunities across our diverse business lines – Retail Banking, Commercial Banking, National Finance, and Wealth Management.
Job Description Summary
Provides high quality customer service by processing customer service transactions efficiently and accurately and uncovering cross sell opportunities of bank products or referring customers to other areas of the bank.
Essential Job Functions
- Processes customer transactions accurately of all deposits, transfers, withdrawals, and other transactions in accordance bank policies, procedures and regulatory requirements.
- Identifies sales and cross selling opportunities and makes qualified referrals to specialist sales partners.
- Performs outbound calls for service/sales follow up in support of MCCRM goals.
- High School Diploma or GED Required
Work Experience
- S1 - None Requires limited job knowledge of systems and procedures. Follows basic work routines and standards.
Typically does not require prior experience.
- Good customer service skills that includes verbal and communication skills
- Good knowledge of Bank deposit and credit products; regulatory requirements
- Results driven
- Good at building relationships, collaboration and team work
- Good problem solving skills
Equal Employment Opportunity Policy
Bank of the West is an Equal Opportunity employer and proud to provide equal employment opportunity to all job seekers without regard to any status protected by applicable law. Bank of the West is also an Affirmative Action employer - Minority / Female / Disabled / Veteran.
Bank of the West will consider for employment qualified applicants with criminal histories pursuant to the San Francisco Fair Chance Ordinance subject to the requirements of all state and federal laws and regulations.


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"I don't know why people have children when they cannot afford them and leave it up to others to take care of them."
"I am a retired truck driver with a heavy foot. Every time I was pulled over and the officer saw I was from Savannah, I was asked if I knew Paula Deen. I spun many yarns about knowing her personally and got out of many tickets. The whole country is fascinated with her. Paula Deen and SCAD are the best things to happen to Savannah."
"The mayor must be bored. What prompted him to come up with this non-smoking ban? People who want to socialize in groups will find a way. Package shop sales will increase and smoking will not stop. The worst will be an increase in drunken driving."
"All Obama's stimulus money and low mortgage rates just help the rich get richer. People with equity are refinancing to buy other things with equity loans. Go figure."
"How much do we spend per year for one student to be educated in the state of Georgia?"
"It appeared that Sonny Dixon of WTOC TV got emotional while reporting on the Hinesville soldier killed in Afghanistan. Sonny, I got emotional, too."
"I agree that local television stations are pushing hurricane information down our throats. We don't need it until a hurricane is on its way."
"It took 10 days for a letter to get to Kentucky from Rincon? When I send a bill payment through the mail, it seems to get there the next day, no matter how far it goes. Go figure."