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Advanced Cleaning
Innovative technology delivers better results. Now there's a guaranteed way to better oral health. It's the new Philips Sonicare FlexCare that adapts to your oral care needs. See all benefits
Philips Sonicare electric toothbrush's unique dynamic action gently and effectively reaches deep between teeth and along the gumline.
The dynamic cleaning action of this toothbrush and the direct broader contact with each tooth, has proven to remove everyday stains, to help keep teeth naturally whiter.
This Philips Sonicare electric toothbrush provides optimal cleaning between teeth and along the gumline for improved gum health in just two weeks.
2-minute timer on this Philips Sonicare electric toothbrush helps ensure dental professional recommended brushing time
30 seconds interval timer indicates when you have completed each quadrant of your mouth and signals for you to move on resulting in more consistent cleaning throughout your mouth
Gently increases power over first 14 uses to ease into the Philips Sonicare electric toothbrush experience
Philips Sonicare's best teeth whitening: this toothbrush helps to remove and reduce stains on your teeth for a brighter smile.
Patented Sonic Technology removes up to 2x more plaque than a manual toothbrush.
Philips Sonicare toothbrush with Sensitive Mode: Gentle, yet thorough cleaning for sensitive gums
Sonicare electric toothbrush's unique dynamic action gently and effectively reaches deep between teeth and along the gumline.


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Home prices are in the gutter, and despite the recent rally, stocks are still 30% off their 2007 peak, so for many people nearing retirement age, plans to kick back and relax have gone out the window.
To repair their nest eggs, many who were looking forward to retirement have postponed their plans for years.
They might find luck looking for work in our Silver-Collar Capitals–the 10 cities with the highest percentage of workers aged 62 and older as of 2008, the latest period for which Census data is available.
In all of the top 10 cities, more than a quarter of retirement-age workers still come into the office. (Because of the greater uncertainty in smaller cities, we only looked at cities with senior citizen labor forces above 10,000.)
In Depth: America's Silver-Collar Capitals
The Silver-Collar Capitals are spread all across the U.S. In Anchorage, Alaska, 31% of seniors still work, the highest rate in the country–and almost none of the seniors looking for jobs are unable to find one, according to the Census data.
In Washington, D.C., and southern Connecticut, 30% and 27%, respectively, of seniors are still working. In Washington, that translates to more than 200,000 seniors still in the work force. The Texas cities of Dallas and Houston have sizable silver-collar workforces as well.
State capitals are humming with seniors who are still working: More than a quarter of seniors are still on the job in Des Moines, Iowa; Lincoln, Neb.; Tallahassee, Fla.; and Raleigh, N.C.
The unemployment rate for seniors–meaning those in the labor force looking for work but unable to find it–is low. The metro areas for Tallahassee and southern Connecticut had the highest unemployment rate for seniors on this list: only 4.7%.
Will the recession cause that rate to spike even higher as more and more seniors try to rebuild retirement assets? Not necessarily, say economists Courtney Coile and Phillip Levine. In a recent paper titled "The Market Crash and Mass Layoffs: How the Current Economic Crisis May Affect Retirement," Coile and Levine found that some people approaching retirement will choose to work more after their retirement accounts decline, but others will retire earlier than expected in the face of a weak labor market.
Coile and Levine predict that, on balance, the weak labor market will cause so many people to retire early that it will offset all the people staying in the job market because of the stock market's fall.
That's good news for those silver-collar seniors looking to rebuild–a bit less competition in a tough job market.

subset: commoncrawl


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My Blog
Is anyone here from Maryland?
Thu, March 26, 2009 - 1:55 PM
Thu, March 26, 2009 - 1:55 PM -
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2 Comments
2 Comments |
add a comment |
Sat, December 19, 2009 - 5:36 AM
strange place to ask the question...
...but there are lots of people here, at tribe, from Maryland...and DC. Try a tribe people search and lots of folks will come up. Of course, I'm certain there is an even larger amount on Facebook or MySpace (wouldn't know personally) but tribe is much more eclectic!
cheers-n-blessings! |


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Dictionary Terms Explained
Doreen Virtue
Doreen Virtue, Ph.D., is a psychotherapist who works with the angelic realm. A clairvoyant since childhood, Doreen teaches people practical ways to work with the Angels to heal their lives. She has appeared on countless TV talk shows in the US, where she is frequently referred to as 'The Angel Lady.' Dr Virtue gives angel readings at workshops throughout the world; and she teaches audience members how to see, hear, feel, and know their guardian angels.
Hay House
- Worldwide book publisher
Hay House is a publishing company specialising in self-help and transformational books that was originally founded in 1984 by author Louise L Hay. It initially provided Louise with a way to self-publish her first two books, Heal Your Body and You Can Heal Your Life, and has been hugely successful ever since.
As Hay House grew, it became an incorporated company in 1987 and began publishing CDs, DVDs, card decks and other items, as well as books. The company is renowned for being one of the fastest-growing publishers of self-help and transformational books and their products are sold in 35 countries around the world.
They currently publish in the region of 300 books and 350 audio products, by over 130 top notch authors. Some of the authors they publish include Sylvia Browne, John Edward, Deepak Chopra, Marianne Williamson, Barbara De Angelis, Phil McGraw, Suze Orman, Carnie Wilson and Wayne Dyer.
The Hay House book imprints include New Beginnings Press, Princess Books and Smiley Books. The company covers a vast range of subject topics, including books on astrology, alternative health, angels, nutrition, parenting, psychology, sociology, meditation, spirituality, numerology, colour therapy, feng shui, business, memoirs and autobiographies.
In March 2005, Hay House launched an online Internet Radio Station, called HayHouseRadio.com. The radio station broadcasts a weekly radio programme, called Radio For Your Soul, which features input, talks and shows from key Hay House authors.
Hay House is located in Carlsbad, California, but has international divisions in the UK, Australia, India and South Africa.


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For the Cubs, meanwhile, the misery continued. They dropped their sixth straight to match their longest skid this season, and they never regrouped once the White Sox started knocking the ball out of the park.
Back-to-back homers by Beckham and Dunn leading off the fourth gave them a 2-0 lead. Flowers made it 3-0 with a drive to start the fifth off Paul Maholm (4-3), giving the White Sox three homers for the second straight game and Peavy (5-1) all the support he needed.
The right-hander struck out seven and walked two over 6 1-3 innings. He helped chase Maholm during a two-run seventh, grounding into a force and scoring on a sacrifice fly, and he left to cheers with a runner on first after retiring Ian Stewart on a fly to right in the bottom half.
It was a charged weekend in Chicago, with Kerry Wood retiring and Konerko getting hit in the face, not to mention the protests in the city surrounding the NATO Summit.
There was heightened security outside Wrigley Field. Inside, it was more of the same.
Peavy shook off a rough outing against Detroit and got back to dominating.
Maholm got hit hard, allowing five runs and nine hits over 6 1-3 innings after going 4-0 in his previous five starts.
He was sailing along until Beckham lined the first pitch of the fourth to the street beyond the left-field bleachers for his fourth homer. Dunn followed with a drive to center on a 2-2 pitch for his second home run in as many games and 43rd against the Cubs. Among active players, only Albert Pujols has more with 53.
That shot also gave the White Sox back-to-back homers in consecutive games, with Dayan Viciedo and A.J. Pierzynski turning the trick on Saturday.
After Peavy escaped a bases-loaded jam in the bottom half, Flowers added to the lead when he started the fifth with his second homer. He also came around on Peavy's grounder after leading off the seventh with a double.
Notes: Although the team has not announced his signing, manager Robin Ventura said veteran INF Orlando Hudson is on his way and that 3B Brent Morel is likely headed to the disabled list because of lower back soreness. A four-time Gold Glove second baseman, Hudson was waived Thursday by San Diego. He will probably see time at third. ... Gavin Floyd is scheduled to start Tuesday, with P.J. Walters going for the Twins. ... Matt Garza starts Monday for the Cubs against Houston, with Bud Norris taking the mound for the Astros. ... Manager Dale Sveum said the Cubs will soon discuss calling up Anthony Rizzo from the minors. It's not hard to see why, considering he's batting .353 with 14 homers and 39 RBIs for Triple-A Iowa. "That's definitely going to be talked about," manager Dale Sveum said. "He's done everything he can down there, but when you bring somebody up like that he's got to play every day so that's the million dollar question. How do we get him playing time?" ... RHP Carlos Marmol (strained right hamstring) and C Steve Clevenger (right oblique) start rehab assignments in Iowa on Monday.


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PC Zombie Gaming – Attack of the Paper Zombies
by admin on Feb.21, 2010, under Game, Video
Attack of the Paper is a completely free, completely ass kicking Indie game devleoped by IndieBird (Download Link) You are in control of a small group of marines set down to battle endless hordes of Zombies. Paper Zombies give you basic RTS control with handdrawn topdown graphics. Theres enough tutorial maps to teach you the basics of the game. The controls are simple and the action is intense making this one fun game. I was worried about the game getting boring after awhile but that is not the case in Attack of the the paper Zombies. The zombies upgrade as the game goes on, and the hordes can become gargantuan in size later on. As well as upgrading zombies you can outfit your marines with better guns, give them siege weaponry and gun turrets. The game is a blast but beware it can be challenging at times. It is highly recommended for zombie fans looking for a free game to play on their PC's.
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Bring on the Zombie Apocalypse with Infectonator: World Dominator | BrainsBrainsBrains
March 2nd, 2010 on 3:19 am[...] of fun and will run on your toaster (provided your toaster has a mouse). May I also recommend Attack of the paper Zombies it [...]


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The Boston Pops Orchestra, founded in 1885, gained national recognition during the substantial tenure of Arthur Fiedler, who was its music director from 1930 through 1979. John Williams left his own legacy conducting the so-called America's Orchestra from 1980 to 1993. That left big shoes to fill when the Boston baton was passed to Keith Lockhart, in 1995.
Lockhart, 54, has conducted some 1,500 Boston Pops concerts, appeared in more than 70 TV shows with the orchestra, including the annual "Boston Pops Fireworks Spectacular" on CBS. He and the Pops have released eight albums with RCA Victor and four self-produced albums including the new "A Boston Pops Christmas — Live From Symphony Hall."
The Boston Pops Esplanade Orchestra and Lockhart come to the Valley and Orange County this week, where they will be performing a wide-ranging program, including works by Williams (the Boston Pops laureate conductor), Leonard Bernstein, Aaron Copland and Duke Ellington, as well as new arrangements of songs by Queen and ABBA.
Lockhart discussed Fiedler's legacy, the Very Best of the Boston Pops Tour and the orchestra's holiday CD over the phone from his home in Boston.
CRITICS' PICKS: What to watch, where to go, what to eat
How many concerts do you conduct in Boston every year?
The Pops collectively does about 100 concerts a year in Boston and another 20 concerts in other venues in New England, especially out in Tanglewood, our summer home.
You're also the chief conductor of the BBC Concert Orchestra in London. How do you juggle both batons?
I am over there probably only eight weeks out of the year, so it's a little less intense schedule than the Pops. It's a lovely relationship that allows me stay here most of the time. I have two small kids at home.
It's remarkable to think that Arthur Fiedler was the conductor of the Boston Pops for almost 50 years.
While Fiedler was here he managed to put the orchestra front and center through a lot of different venues. It was one of the first orchestras to record in this country and to record extensively. So extensively, that probably by World War II every house that had a gramophone had a Boston Pops record. It was the first orchestra to go on TV regularly with "Evening at the Pops," which started in 1970 and didn't stop until 2004. All of those things gave the orchestra a national branding, which we have tried to maintain.
PHOTOS: Arts and culture in pictures by The Times
The tour is called the Very Best of the Boston Pops. So what are some of the highlights of the concert?
We consider ourselves America's Orchestra and thus, the core of our repertory is really great music written for orchestra by American composers.
The first half includes Dvorak's "Largo" from the "New World Symphony" because he came to the United States at the end of the 19th century during which he wrote the "New World Symphony" and served as a cheerleader for a just developing real unique American-style school of composition.
Besides Dvorak, the music includes Copland's "Rodeo" and Gershwin's "Rhapsody in Blue." The second part we go a little bit broader into the world of Broadway, world music and some contemporary stuff, as well as paying tribute to John Williams.
I read the Pops has an amazing library of arrangements.
It's literally something like 3,000 unique arrangements. During the Fiedler era, the orchestra tended to go to one or two selected orchestrators, especially Leroy Anderson, who did so much for the Pops. He wrote "Sleigh Ride" and "The Typewriter."
These days we actually put our work out to several arrangers and match arrangers to the project.
Speaking of "Sleigh Ride," I'm sure that's included on your new holiday CD, "A Boston Pops Christmas — Live From Symphony Hall."
Of course, and a new arrangement of "The 12 Days of Christmas" we first did about five years ago, which has become the modern "Sleigh Ride." It's a total showstopper. It's almost impossible to describe. It has everything but the kitchen sink thrown in. It's witty and fun without being pretentious.
This is the third holiday album that I have done with the Pops in my time here. What we did for the first time is record a live Christmas album with the idea being to try to capture the ambience of being at a Boston Pops Christmas concert. For our audiences back here on the East Coast, one of the things they know us for most is that we do 45 to 50 Christmas shows every year in Boston and surrounding New England areas. They have become a tradition here.
Boston Pops Esplanade Orchestra
When and where: 8 p.m. Thursday at the Valley Performing Arts Center at Cal State Northridge and 8 p.m. Friday at the Renée and Henry Segerstrom Concert Hall in Costa Mesa
Cost: $45-$350
Info: http://www.valleyperformingartscenter.org or http://www.philharmonicsociety.org
PHOTOS: Hollywood stars on stage CHEAT SHEET: Spring arts preview 2014 PHOTOS: Arts and culture in pictures


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In my early days as a writer, I never used to be a great fan of research. I probably took the old advice 'write about what you know' rather too literally. But all too soon, I ran out of things I knew – and I needed to find out more intriguing stuff to make sure that my new stories remained fresh and, where possible, 'different'. Over the past few years, I've done a great deal of research, and although it can be time-consuming, it's also very enjoyable.
Often, research is straightforward, at least in theory. To write credible Lake District scenes set in the bleak midwinter, for instance, you really have no choice but to brave the elements and see what the place is like when the tourists are few and far between. It was relatively easy, when writing Waterloo Sunset, to explore places in Liverpool where scenes were set – the map on my website highlights some of them. And the marvellous help given to me by the City Coroner, Andre Rebello, made a real difference to key aspects of the story.
Reading the newspapers can be very useful – so can surfing the net. I keep press cuttings about things that strike me as odd or entertaining, and a story I clipped from a national newspaper 20 years ago has helped me with the novel I'm writing at present.
But sometimes effective research takes a much less tangible form – it can be more a matter of talking to people, and letting ideas seep into your consciousness. The joy of escapist fiction is that the incidents and characters that emerge are very different from those you have encountered in real life. And yet, without the spark of a stimulating conversation, you might never have had those ideas. Something I remind myself of when in anti-social mood!
Over the past fortnight, for instance, I've had the pleasure of conversations with some fascinating people, including a barrister, a judge, a retired taxman, and a former SAS man, as well as soaking up the atmosphere in the directors' box and guest lounge at a big football match. The conversations were fun for their own sake, and I wasn't particularly discussing plot ideas with my companions, but they are all knowledgeable and friendly people, with interesting things to say not only about their work, but also about life in general. Perhaps one of these days, their insights will help inspire a plot element in a future story - it's the closest I can get to defining 'inspiration'. But just in case they don't, I'll keep devouring any scraps of information that catch my interest, from any source I can find.
Thursday, 5 February 2009
2 comments:
- Barbara Martin said...
Whenever I hear a conversation that piques my attention I make a quick jotting down on a pad I carry for that purpose. I'm like you in that sense, of using an overheard comment or seeing something odd in my manuscripts.
- 6 February 2009 at 00:03
- Martin Edwards said...
Hi Barbara, good to hear from you. I think Agatha Christie did the same. One phrase that she overheard gave her material for two different novels - quite something!
- 6 February 2009 at 09:10
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There are no Upcoming Shows listed for this comedian.
Brody Stevens
Brody Stevens is the executive producer and star of the unique Comedy Central TV series "Brody Stevens: Enjoy It!", co-created and produced by Zach Galifianakis. Brody is also the host of two popular podcast series - "The Steven Brody Stevens Festival of Friendship" on the Feral Audio Network, and "Brode and Esther" on Deathsquad. In addition, Brody hosted his own live video podcast "Positive Push with Brody Stevens" on Youtube's Video Podcast Network.
Stevens has appeared on Conan, Chelsea Lately, @midnight, Premium Blend, TMZ, The Late Late Show with Craig Kilborn, Late World with Zach, The Best Damn Sports Show Period, Tosh.0, Fox NFL Sunday, Playboy Morning Radio and on podcasts by Jay Mohr, Joe Rogan and WTF with Marc Maron. Brody also appeared in the movies Jesus Is Magic, Due Date, The Hangover and The Hangover Part II. He was, however, cut out of the movie Funny People.
Most recently, Brody released his Comedy Central Half-Hour Special in January, 2014.
Brody Stevens's Upcoming Shows
Brody Stevens is Known For
Credit | Details | Role |
Chelsea Lately | E! | Self |
The Late Late Show | CBS | Self |
The Hangover | Feature Film | Officer Foltz |


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Definitions of plunk
v. t. - To pluck and release quickly (a musical string); to twang.
v. t. - To throw, push, drive heavily, plumply, or suddenly; as, to plunk down a dollar; also, to hit or strike.
v. t. - To be a truant from (school).
v. i. - To make a quick, hollow, metallic, or harsh sound, as by pulling hard on a taut string and quickly releasing it; of a raven, to croak.
v. i. - To drop or sink down suddenly or heavily; to plump.
v. i. - To play truant, or "hooky".
n. - Act or sound of plunking.
n. - A large sum of money.
n. - A dollar.
The word "plunk" uses 5 letters: K L N P U.
No direct anagrams for plunk found in this word list.
Words formed by adding one letter before or after plunk (in bold), or to klnpu in any order:
i - linkup uplink s - plunks
Shorter words found within plunk:
lunk nu pul pun punk un up
List shorter words within plunk, sorted by length
Words formed from any letters in plunk, plus an optional blank or existing letter
List all words starting with plunk, words containing plunk or words ending with plunk
All words formed from plunk by changing one letter
Other words with the same letter pairs: pl lu un nk
Browse words starting with plunk by next letter
Previous word in list: plunging
Next word in list: plunked
Some random words: if oecologies caporal etape evulsion ovular ciao
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text: Fighting Illini Are Everywhere, Even In North Texas's Starting LineupBarry Petchesky3/09/11 10:15amFiled to: OopsEspnIllinois Fighting IlliniNorth Texas Mean GreenMedia Meltdowns14EditPromoteShare to KinjaToggle Conversation toolsGo to permalink None of these gentlemen are actually members of the North Texas Mean Green. They are, from left to right, current and former Illinois players Warren Carter, Jack Ingram, Rich McBride, Demetri McCamey, and Jamar Smith. We'd say it was a glitch or an honest mistake, but those five players have never been on a team together. So we're guessing there's an Illinois alumnus in ESPN's truck who's pretty proud of himself this morning. (Thanks to eagle-eyed tipsters Matthew, Nathan and Daniel) Advertisement Things didn't get better for North Texas, either: Reply14 repliesLeave a reply


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IRVINE, Calif.--(BUSINESS WIRE)--Impac Mortgage Holdings, Inc. (NYSE MKT: IMH) announces origination volume of $2.4 billion in 2012 as compared to $885 million in 2011, and a 93% increase in net earnings of continuing operations to $12.2 million in 2012, as compared with $6.3 million in 2011.
Selected Financial Data | |||||||||||||||||||||
(in millions) | |||||||||||||||||||||
YTD 2012 | YTD 2011 | Increase | % Change | ||||||||||||||||||
Originations | $ | 2,419.7 | $ | 883.2 | $ | 1,536.4 | 173 | % | |||||||||||||
Service Retained Sales | 2,212.1 | 419.9 | 1,792.2 | 427 | % | ||||||||||||||||
Servicing Portfolio | 2,177.2 | 605.4 | 1,571.8 | 260 | % | ||||||||||||||||
Warehouse Capacity | 217.5 | 87.5 | 130.0 | 149 | % | ||||||||||||||||
Segment Results | YTD 2012 | YTD 2011 | |||||||||||||||
(in thousands) | Net earnings | Net earnings | |||||||||||||||
(loss) | Diluted EPS | (loss) | Diluted EPS | ||||||||||||||
Mortgage Lending | $ | 16,599 | $ | 2.10 | $ | (11,648 | ) | $ | (1.39 | ) | |||||||
Real Estate Services | 12,640 | 1.60 | 19,946 | 2.39 | |||||||||||||
Long-term Portfolio | (17,065 | ) | (2.16 | ) | (1,996 | ) | (0.24 | ) | |||||||||
Continuing Operations | $ | 12,174 | $ | 1.54 | $ | 6,302 | $ | 0.76 | |||||||||
Discontinued Operations | (15,549 | ) | (1.96 | ) | (3,078 | ) | (0.37 | ) | |||||||||
Net (loss) earnings attributable to IMH | $ | (3,375 | ) | $ | (0.42 | ) | $ | 3,224 | $ | 0.39 | |||||||
Segment Results | Q4 2012 | Q4 2011 | |||||||||||||||
(in thousands) | Net earnings | Net earnings | |||||||||||||||
(loss) | Diluted EPS | (loss) | Diluted EPS | ||||||||||||||
Mortgage Lending | $ | 4,265 | $ | 0.53 | $ | (2,930 | ) | $ | (0.35 | ) | |||||||
Real Estate Services | 3,187 | 0.39 | 4,689 | 0.56 | |||||||||||||
Long-term Portfolio | (5,822 | ) | (0.72 | ) | 235 | 0.03 | |||||||||||
Continuing Operations | $ | 1,630 | $ | 0.20 | $ | 1,994 | $ | 0.24 | |||||||||
Discontinued Operations | (2,147 | ) | (0.26 | ) | (1,246 | ) | (0.15 | ) | |||||||||
Net (loss) earnings attributable to IMH | $ | (517 | ) | $ | (0.06 | ) | $ | 748 | $ | 0.09 | |||||||
The continuing operations, comprised of mortgage lending, real estate services and our long-term portfolio, earned $1.54 per diluted share in 2012 as compared to $0.76 per diluted share in 2011. The increase was primarily associated with the increase in net earnings from mortgage lending activities due to the growth in both mortgage lending originations and the retention of mortgage servicing rights. In the fourth quarter of 2012, continuing operations experienced a slight decline in net earnings to $0.20 per diluted share as compared to $0.24 per diluted share for the fourth quarter of 2011. The decline was primarily due to a reduction in the estimated fair value of the long-term mortgage portfolio in 2012 compared to the prior year.
Mortgage Lending
In 2012, net earnings from mortgage lending improved 242% to $16.6 million as compared to a net loss of $(11.7) million in 2011. In the fourth quarter of 2012, net earnings from mortgage lending increased to $4.3 million as compared to a loss of $(2.9) million in the fourth quarter of 2011. Both increases were due to higher levels of mortgage originations, as well as an increase in the retention of mortgage servicing rights from service-retained sales, which increased the mortgage servicing portfolio. Mortgage originations increased to $813 million in the fourth quarter of 2012 compared to $345 million in the fourth quarter of 2011 and the mortgage servicing portfolio increased with service-retained loan sales of $781 million in the fourth quarter of 2012 as compared to $289 million in the fourth quarter of 2011.
Although mortgage originations and service-retained loan sales increased by 15% and 24%, respectively, in the fourth quarter of 2012 as compared to the third quarter, net earnings of mortgage lending were lower in the fourth quarter of 2012 as compared to the third quarter. This was due to a larger than anticipated decline in the mortgage origination pipeline in the quarter primarily caused by an anticipated seasonal decline combined with the impact from the Federal Reserve's QE3 program initiated in September. The initial effect on interest rates from the QE3 program was a rise in interest rates at the end of September. This resulted in an increase in applications, during September, from prospective borrowers wishing to lock in an interest rate before further interest rate increases, increasing our mortgage origination pipeline at September 30, 2012, to its highest point during the year. The Company records an interest rate lock derivative each period representing the estimated fair value of our mortgage origination pipeline. With a significant decrease in the pipeline in the fourth quarter combined with fourth quarter margin compressions in the mortgage industry, the estimated fair value of the interest rate lock derivative declined $5.4 million.
In 2012, the mortgage lending channels that experienced the largest percentage of growth were our retail and correspondent channels. Our retail channel, which is our consumer direct channel conducted by our branch offices, increased average monthly production to approximately $60 million and our correspondent channel, which acquires closed loans from our correspondent sellers, increased monthly production significantly from approximately $3 million in January to average monthly production of approximately $33 million in 2012. For 2012, our retail channel production contributed 28% of originations while our correspondent channel contributed 17%, with the remaining 55% coming from the wholesale channel.
With our strategy to increase the mix of purchase money transactions, in 2012, we have continued to devote efforts towards capturing additional purchase money transactions as the real estate market continues to improve and interest rates continue to rise, which we believe will cause the home refinance market to shrink. Through our proprietary technology, we have been able to increase the number of relationships we have with real estate professionals, leading to more purchase money transactions. In 2012, while the mix of purchase money transactions and refinance loans has remained consistent across the year, the number of purchase money transactions has doubled from first quarter 2012 to fourth quarter 2012. In addition, we have enhanced our product offering to include more loan products less sensitive to changing interest rates, including FHA 203(k), a home improvement loan that provides the borrower funds to make renovations, reverse mortgages, Home Affordable Refinance Program (HARP) loans and intermediate Adjustable Rate Mortgages.
Our mortgage servicing portfolio increased to $2.2 billion at the end of 2012, from $605 million at the end of 2011. At December 31, 2012, the loans that were originated after 2010 totaled $2.06 billion with a minimal number of loans 60 or more days delinquent. The remaining $114 million balance of the portfolio consist of loans originated by AmeriHome, primarily prior to 2009 and was acquired in the 2010 purchase of AmeriHome. These legacy AmeriHome loans continue to have high delinquencies due to declining principal balances.
The expansion of mortgage lending volumes has been made possible by increases in our warehouse borrowing capacity to $217.5 million at December 31, 2012, including the addition of a major national financial institution, from $87.5 million at the end of 2011. Plus, we recently obtained approvals from another well-known national warehouse lending bank for a new warehouse facility and increases to our existing warehouse lenders for an additional $100 million in total warehouse capacity, which we believe will further provide us the ability to increase mortgage originations.
Real Estate Services
Net earnings from our real estate services segment decreased to $12.6 million from $19.9 million in 2011. The decrease was primarily due to a continued and expected decline in the long term mortgage portfolio resulting from collections and liquidation of defaulted loans. We believe, however, that if portions of our master servicing portfolio are transferred to new servicers, there may be an opportunity to offer and expand our real estate services, although currently we expect a gradual decline in revenues and net earnings of real estate services.
Long-term Mortgage Portfolio
Our long-term mortgage portfolio had a net loss of $(17.1) million in 2012 compared to a net loss of $(2.0) million in 2011 primarily due to the change in the estimated fair value of the portfolio. The estimated fair value of the net trust assets declined in 2012 as a result of $10.2 million in residual cash flows received combined with updated assumptions applied to certain securitization trusts within the long-term mortgage portfolio at December 31, 2012 which assumptions are based on the expectation of an acceleration of foreclosure liquidation losses in the near future.
Consolidated Operations
In 2012, the Company reported a consolidated net loss of $(3.4) million or $(0.42) per diluted share, as compared to net earnings of $3.2 million in 2011 or $0.39 diluted per share, with the decrease primarily due to the change in the estimated fair value of the long-term mortgage portfolio in 2012. Net earnings were also adversely effected by the previously announced settlement charge of $6.1 million recorded in the third quarter of 2012 as discussed in the September 30, 2012 Form 10-Q and a significant legal fees expense incurred during 2012 defending these matters. For the fourth quarter of 2012, the consolidated net loss was $(517) thousand or $(0.06) per diluted share as compared to consolidated net earnings of $748 thousand or $0.09 per diluted share for the fourth quarter of 2011.
We believe that the continued driver of growth in net earnings from continuing operations for 2013 will be mortgage lending. The key to that growth is not only mortgage origination volume, but also loan quality and operational efficiencies. More specifically, we expect to see the most significant increases in the volume of loans originated through our retail and correspondent channels. We believe that this will primarily be achieved by substantially increasing our active customer base in correspondent lending and hiring additional retail loan officers for our existing offices and call centers and our new retail offices currently planned to be opened during 2013. Our wholesale lending channel will continue to be a key component of our origination platform, however, in 2013, we will focus on retail and correspondent channels in an effort to have originations more equally balanced across all of our channels. We believe that each our channels, retail, correspondent and wholesale, will benefit from (i) our recently launched programs including prime jumbo program, FHA 203(k), and reverse mortgages, (ii) the increase in our operational capacities with the opening of new operations fulfillment centers, and (iii) the implementation of a new loan origination system, and the integration of new technology designed to capture and index loan documentation and data to more completely automate the origination process. We expect the new loan origination system and documentation and data technology will also help us to ensure loan quality and improve operational efficiency.
Lastly we will continue to further enhance the brand of the "Impac" name with increased consumer direct and business to business awareness through our social media, public relations campaigns and industry wide marketing. We believe our efforts in creating better "Impac" brand awareness over the last year not only assisted our origination efforts but have enhanced our recruiting efforts for quality mortgage professionals.
Looking forward to 2013, Mr. Joseph Tomkinson, Chairman and CEO of Impac Mortgage Holdings, Inc., commented, "We expect that the culmination of our strategies and initiatives instituted over the last year will not only allow us to continue to grow but also solidify the foundation to deliver more consistent results."
Conference Call
The Company will hold a conference call tomorrow morning, February 28th, 2013, at 9 a.m. Pacific Time (12:00 p.m. Eastern Time), to discuss the Company's financial results and business outlook and to answer investor questions,. After the Company's prepared remarks, management will host a live Q&A session, to answer questions submitted via email. Please email your questions to email@example.com. Investors may participate in the conference call by dialing (866) 573-1930, conference ID number 21650817, or access the web cast via our web site at http://ir.impaccompanies.com. To participate in the conference call, dial in 15 minutes prior to the scheduled start time. The conference call will be archived on the Company's web site at http://ir.impaccompanies.com.
Forward-Looking Statements
This press release contains certain forward looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward looking statements, some of which are based on various assumptions and events that are beyond our control, may be identified by reference to a future period or periods or by the use of forward looking terminology, such as "may," "will," "intends," "believe," "expect," "likely," "appear," "should," "could," "seem to," "anticipate," "expectations," "plan," or similar terms or variations on those terms or the negative of those terms. The forward looking statements are based on current management expectations. Actual results may differ materially as a result of several factors, including, but not limited to the following: our ability to manage effectively our mortgage lending operations and facilities and continue to expand the Company's growing mortgage lending; volatility in the mortgage industry; unexpected interest rate fluctuations; decrease in purchase money transactions; inability to hire qualified retail loan officers or transact with qualified correspondents; failure to successfully launch or continue to market new loan products; increased competition in the mortgage lending industry by larger or more efficient companies; issues and system risks related to our technology; more than expected increases in default rates or loss severities and mortgage related losses; ability to obtain additional financing and the terms of any financing that we do obtain; increase in loan repurchase requests and ability to adequately settle repurchase obligations; failure to create brand awareness; the outcome, including any settlements, of litigation or regulatory actions pending against us or other legal contingencies and our compliance with applicable local, state and federal laws and regulations and other general market and economic conditions
For a discussion of these and other risks and uncertainties that could cause actual results to differ from those contained in the forward looking statements, see the annual and quarterly reports we file with the Securities and Exchange Commission. This document speaks only as of its date and we do not undertake, and specifically disclaim any obligation, to release publicly the results of any revisions that may be made to any forward looking statements to reflect the occurrence of anticipated or unanticipated events or circumstances after the date of such statements
About the Company
Impac Mortgage Holdings, Inc. (IMH or Impac) provides mortgage and real estate solutions that address the challenges of today's economic environment. Impac's operations include mortgage lending and servicing, portfolio loss mitigation and real estate services as well as the management of the securitized long-term mortgage portfolio which includes the residual interest in securitizations.
For additional information, questions or comments, please call Justin Moisio in Investor Relations at (949) 475-3988 or email email@example.com. Web site: http://ir.impaccompanies.com or www.impaccompanies.com


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Liquitex Freestyle Traditional Detail Brushes are made from the highest quality synthetic nylon which make them ideal for all acrylic applications.
Their long contoured handles provide extra comfort when holding the brushes at the tails but also are nicely balanced so that they provide perfect control when held below the ferrule.
Each artists brush features Synthetic Nylon housed in rust free stainless steel ferrule attached to a long and contoured wooden handle. The brush size is conveniently printed on both the body of the brush and the handle tip for easy identification while painting.
Brand | Liquitex |
Series | Freestyle |
Shape | Flat |
Material | Synthetic Nylon |
Handle Type | Long Handle |
Size | 2 |
Length | 1/2" |
Width | 1/4" |
No. | 1300302 |


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Last weekend we saw photos from the Paris, France set of Gossip Girl which has been filming some of its 4th season in the City of Lights all last week and we got a sneak peek of what kind of drama is in store for BFF/frenemies Serena van der Woodsen (played by Blake Lively) and Blair Waldorf (played by Leighton Meester). Today we see that Blake has already made her way back home to NYC and was spotted with her GG co-star and real life boyfriend Penn Badgeley lookin' all hot and heavy together in the Big Apple:
No, the couple were not filming a scene for Gossip Girl … they were just being all gropey in real life. You know, I'm actually surprised that these two are still together. I guess I had forgotten that they broke up on the show, not in real life … cuz I'm really bad at separating fact from fiction. In any event, I kinda love how into one another BlakeLey seem to be. They make a hawt couple, yeah?
[Photo credit: INFdaily]


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Instead we are treated to images such as that of baby Omar Mishrawi on the front page of the Washington Post and other media outlets.
4. Moralizing over Israel's interests
Newspaper reports have appeared alleging Israeli lobbying on behalf of the Egyptian military-backed government, including in the New York Times and Wall Street Journal. To the uninformed and those with a low opinion of Israel, this could imply support for the violent actions of the Egyptian army. With a healthy dose of cynicism, Shmuel Rosner responds in the NY Times: "Here we go again. Israel is rooting for another butcher" before spelling out the realities:
Israelis are not immune to being cold-hearted, cynical, hypocritical and racist. But this position is something else. If Israelis are rooting for Egypt's military, it's because they want a government next door that will respect the two countries' peace treaty. And it's because the military is the only institution in Egypt today that can prevent the Sinai Peninsula from becoming a safe haven for radicalism. Israelis are being pragmatic, and that might look ugly, but that's what experience has taught them.
Indeed, Israel does not have the luxury of favoring liberal democratic forces over extremists, radicals or authoritarians. In a rough neighborhood you can only pick from the best of a bad bunch.
5. Journalists engaged in propaganda
The Egyptian Independent carries a feature on the polarization and abuse of Egyptian media:
Qutb al-Arabi, assistant secretary general of the Supreme Council of Journalism, said that he knows of some newspapers that refrained from publishing some writers' articles for opposing their owners' political affiliations, others banned media professionals from TV shows so as not to express the other point of view.
Jaqueline Zaher of DPA believes that the Egyptian media have become "vessels" for political powers.
"Authentication and double-checking news are not on the table for many of them. Rumors and half-leads were considered okay to publish or air," she said. "This was either due to an avarice to publish more news to feed the audience that is always hungry for information, or, in most cases, to serve political agendas of the media owners."
Al-Arabi also said that anonymous sources have run rampant in Egyptian media, making it easy for some newspapers to get away with inaccurate news.
Media outlets private and state-owned are steamrolling moderate, unpolarised opinions and news coverage leaving average Egyptians confused, while those affiliate to either side of Egypt's political divide complain of media bias or resort to the end of the spectrum that confirms their bias and feed it even more, leaving little room for unbiased reports.
Egyptians are confused and the deep polarisation present in the street proves that few of them are empowered with the tools needed to weigh news before sharing them on social media or even adopting some of the media's propaganda as personal opinions.
Perhaps Western journalists should stop viewing their Arab colleagues through the lens of Western journalistic practice. There have been plenty of occasions through the years where Palestinian journalists have taken an active role in the conflict beyond that of simply reporting.
Only in the past few weeks we exposed the agenda of Palestinian photojournalist Fadi Arouri who previously worked for Reuters while actively promoting a campaign against normalization of relations with Israel.
In May 2013, the Washington-based Newseum, a museum dedicated to the media, even considered including two Hamas activists who worked for the Hamas Al-Aqsa television network in a ceremony to honor those journalists who have been killed in the last year in the course of covering the news.
But as the Egyptian example as well as the activities of some Palestinian media has shown, simply putting down the word "journalist" as one's profession doesn't necessarily equal professionalism.


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Keep your Raspberry Pi B+ safe and protected with the Raspberry Pi B+ Multicomp Case . It features cut outs for all the boards ports and is vented to keep things cool during use. The top of the case also features ribbon openings for the camera, touch screen display and anything else you have connected. Two screw holes let you mount the Raspberry Pi B+ Multicomp Case anywhere, making it ideal for attaching to mobile projects, under a table and anywhere else you can think of.
Check stock and price


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All Products
(5 Total)
View by Size:
Synopsis: | Keeping up an image can be a full time job. |
Directed by: | Tom DiCillo |
Producer(s): | Yoram Mandel, Ruth Waldburger, Steven Starr, Miramax Films. |
Cast: | Brad Pitt, Calvin Levels, Nick Cave, Wilfredo Giovanni Clark, Alison Moir, Peter McRobbie, Tina Louise, Michael Mulheren, Catherine Keener, Samuel L. Jackson |


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Brown to Host Star-Studded Wood-Star Music Festival
Posted: August 7, 2012
Suns shooting guard Shannon Brown is one half of an extremely talented household. Besides Brown being an NBA high-flyer, his wife, Monica, is a chart-topping singer/songwriter that has sold more than 20 million albums worldwide.
With such incredible access to the world of entertainment, Brown is going to utilize his family connections to host the Woodstar Music Festival from August 17-19 in Chicago, IL. A native of Chicago, Brown will tip off the event with a sponsorship dinner on August 17, followed by concerts on August 18 and 19, a basketball clinic on August 18 and a celebrity basketball game on August 19.
All proceeds will go to the Shannon Brown Foundation, a charitable organization which assists in the social development of young people.
"The event is really for my foundation and for the kids," Brown said. "(The funds raised) give scholarships, computers, book bags and things like that to give kids a better chance to succeed in life."
Besides Monica, some of the artists that will be on hand to perform include, Robin Thicke, Dawn Richard, Estelle, Fantasia, Slick Rick, Doug E. Fresh, MC Lyte, Naughty by Nature, Rakim, as well as some up-and-coming local acts.
Through various social media channels, Brown has even encouraged fan participation in the event.
"We picked someone off Twitter to sing the national anthem for the celebrity game," the Suns shooting guard said. "(There was also an opportunity) for a rap and R&B act to (win a chance) to open up for each day of the concert."
The celebrity basketball game will include two former Chicago stars that sported Suns uniforms at one time: Alando Tucker and Dee Brown. The contest will also feature local streetball players and names from the entertainment industry.
Former MTV VJ and funnyman Ed Lover will coach opposite of Brown.
"We're trying to make it a huge annual event that's for a good cause," Brown said.
To learn more about the event, check out woodstarmusicfestival.com.
Any questions or comments for Stefan Swiat? Click here to send him your comments by e-mail.


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Journal "Innovative Marketing", #3/2008
Available files
Some papers of the issue are freely available. Please check contents below for hyperlinks pointing to appropriate files. All other issues will be available only for subscribers, see more information about subscribing and single issue purchasing conditions.
#3/2008. English language version is available in PDF format. Please use Adobe Acrobat Reader versions 5.0/6.0 to view and print this file. |
Contents of issue
Philemon Oyewole, Ephraim Okoro Who pays more in the international market? An examination of terms of trade and tariffs of the countries of Africa |
John Mylonakis Role, objectives and effectiveness of financial advertizing: an exploratory bank marketing study |
Carl Obermiller, Chauncey Burke, April Atwood Sustainable business as marketing strategy |
Tulin Ural The impact of sales management practices on job satisfaction of salespeople |
Constantinos-Vasilios Priporas, Ioannis Poimenidis Services managers' awareness of crisis management: attitudes and preparation |
Sidnei Franco, Peter Wanke, Maria Fernanda Hijjar Satisfaction factors with the use of self-employed people in highway transportation |
Dilber Ulaş, Hatice Çalipinar Evaluating the relationship between brand and supply chains on Turkish SMEs |
Marc Logman Understanding consumers' cognitive maps in today's complex marketing environments |


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Get the thermal imagers that are built on 65+ years of industrial experience. Each camera is built without compromise to the Fluke standard of "ruggedness, reliability and accuracy". Designed for everyday use, in any environment for thorough and accurate inspections. Choose from the affordable and versatile Performance Series, the Professional Series that offers superior image quality, or the Expert Series that gives you up to 1024 x 768 resolution on the industry's largest screen.
The Performance Series infrared cameras offer good image quality at an affordable price. With up to 320x240 resolution, you can see more detail in every image, even from a distance - detail that could indicate a potential issue. With a rugged design and easy-to-use user interface, these cameras are ideal for troubleshooting tasks. Every model comes standard with Fluke Connect® and a smart battery with LED charge indicator, and most models include a removable SD card and an adjustable robust hand strap.
Compare models »
¹ Compared to industrial hand-held infrared cameras in the same price range, based on MSRP as of May 1, 2014.
A Professional Series thermal camera gives you in-focus, crisp, detailed images. Get clear, accurate focus throughout the field of view with MultiSharp™ focus (Ti480 and Ti450), or focus with laser speed and accuracy on your designated target with LaserSharp® Auto Focus. Every model comes standard with Fluke Connect, advanced documentation and viewing features, and a high resolution touchscreen LCD, so you can clearly see what you are measuring and quickly navigate the menu. Measure high temperatures, up to 1200 °C (2192 °F). Add an optional telephoto or wide angle lens for extra detail from near or far.
The Expert Series infrared cameras produce extremely detailed images, and with the large 5.7" LCD displays, you get a premium viewing experience. With the >240° articulating lens, you can navigate over, under and around objects to capture those tough shots with ease. Measure high temperatures up to 1200 °C (2192 °F), and take advantage of the most advanced focus options available for consistently in-focus images, including MultiSharp™ Focus – focus near and far throughout the field of view; LaserSharp® Auto Focus – instant focus on your designated target, and manual focus. Every model comes standard with Fluke Connect. Add an optional IR lens for extra detail from near or far.


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The word in all the media is that the conservatives are upset, and the Democrats are pleased, but it seems to me that there are varied motivations for both the pleasure and displeasure.
David Frum quotes a man who has this to say:
I would vote NO on Miers – and it would hurt my left-leaning heart.
I am a left-leaning independent and I do not like Justices in the mold of Scalia and Thomas. However, I would prefer either of those two to Miers. Miers does not have a proven record of intellectual rigor and strong constitutional principles.
I would prefer a strong, clear, consistent thinker that I disagree with than a chance at a wandering mind with good policy instincts. That's why I liked Roberts. I trust that he will consider the facts and write strong opinions even if I disagree with the policy outcomes. Plus, although he wanted to look at original intent, he clearly stated that the framers intent is often murky and that modern day words have different meanings.
Other liberals seem positively gleeful, not least among them Harry Reid (from MSNBC:
Senate Democratic Leader Harry Reid was complimentary, issuing a statement that said he likes Miers and adding "the Supreme Court would benefit from the addition of a justice who has real experience as a practicing lawyer."
At the same time, he said he looked forward to the "process which will help the American people learn more about Harriet Miers, and help the Senate determine whether she deserves a lifetime seat on the Supreme Court."
Reid had personally recommended that Bush consider Miers for nomination, according to several sources familiar with the president's consultations with individual senators.
In other words, he can't wait for the ensuing Republican squabble, and he's just overjoyed that the base is rebelling.
On the right, the reaction is pretty much all negative or stalling, but there is the same divergence in motivation: there are those that don't care what her qualifications are as long as she votes Scalia's way, and there are those that are genuinely apalled by her lack of qualifications.
Sam Brownback falls in with the former. He desperately wants a shoot-out at OK Corral. The moment that it became apparent that Bush wasn't going to nominate someone like, ah, him, he started grousing.
"What I was hoping for was (Judge Michael) Luttig (of the U.S. Court of Appeals for the Fourth Circuit). (Fifth Circuit Judge) Priscilla Owen, you don't have as much of a record, but you have some. (Fifth Circuit Judge) Edith Jones, you have a much clearer record," he said.
"That's what I was hoping, that we would get that sort of nominee, where there's no guessing game about this, because you have that written record."
"I'd love to have her say Roe v. Wade is unconstitutional; I am doubtful that that is going to happen."
Those that on the right that do support Miers say that they trust the President. Pat Buchanan, on Meet the Press, had this to say to those people:
Listen, there's a possibility she would vote to overturn Roe v. Wade. But what we've heard here, Tim, is "trust, believe." Why should we take this risk? Anti-communism and the Supreme Court are the great causes of conservatism in my lifetime. Ronald Reagan led us to victory in the Cold War. We were on the precipice of victory in the battle to return the Supreme Court to constitutionalism. And the president of the United States picks a woman with no known judicial philosophy who has never taken a stand on any of these great questions, who has never written or said anything about Supreme Court rulings, and we have been told to take it on faith.
On the precipice of victory! And then Mr. Stay-the-Course himself wimps out. Who wouldn't be upset?
The right seemed sure that this was going to be it. The big showdown where the Republicans get to show everyone who's the boss. And then Miers is nominated, and the whole teeth-gnashing conservative machine is forced to grind to an abrupt halt and start equivocating and saying that they don't really like Ms. Miers, but she's still a nice person and all, and Bush is really okay, too, but not sure on this one, just not quite decided yet, you know.
I, for one, am glad that the Republicans were denied their fist-fight. I think there need to be other criteria for a nominee apart from Roe vs. Wade.
On the other hand, she's not very qualified. She won't be a Holmes, or even a Scalia. There were better qualified people that Bush could've nominated. Problem is that most of them have expressed an opinion, which makes them difficult for Bush to nominate in his weakened state.
Miers will not 'move the court' in the way that conservatives might wish, and she certainly won't be a leader, but the Supreme Court has got leaders. How many grandiose theories of existence can it support at the same time? I'm perfectly happy to have her there, not making too much trouble. If anything Miers has shown herself to be cautious. Perhaps because of her lack of an over-arching philosophy on the Constitution, she will take some time to figure out what the Court's rulings will do to people 'on the ground.' That's good enough for me.
Powered by Sidelines


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One of the biggest factors in getting through this treatment , is the success , or otherwise in controlling nausea. Anyone who has ever experienced sea- sickness, knows just how depressing and debilitating it can be. Now imagine sea sickness for weeks , then just when you start to feel better , going right back to square one- voluntarily!!
The good news is lots of drug options to help, the bad news is everyone seems to react differently , so there is no one right answer. At first weren't sure just how much it could be improved and thought that as long as he wasn't vomiting constantly , it was as good as we could hope , but in fact , over the past few weeks have controlled it to a much better level, such that whilst still nauseous at times, never stops him eating and never results in actual sickness.
Over the past few months , this is our experience of the following drugs
Steroids – dexamethasone , starts day before each treatment and continues for four days afterwards. These have proved really effective , seem to stimulate his appetite and keep nausea at bay really well. Their main downside is they do make him a bit hyper at night and disrupt his sleep as well as increasing restless legs syndrome.
Ondansetron – this is given intravenously during the day the chemo is administered, it appears to target nausea actually caused on the day and its immediate aftermath, apparently it works best in conjunction with steroids and is a serotonin blocker. Again this seems to have been really effective as nausea reduced in those first couple of days.
Metaclopramide – this has been the mainstay of our anti nausea controls , normally starts day after the chemo treatment and is taken for round 5 – 9 days, it works by blocking the vomiting centre and encourages the stomach to empty , so that it gets rid of the heavy feeling you have when you feel sick. This had a lot of experimentation. At first we just took along with the steroids and stopped on the same day – this was a bad move as immediately started being sick the day after they stopped and although restarted them , never really got rid of the nausea at all. Also found it was really bad first thing in the morning and during the night, when he was constantly waking up feeling sick and having to run to the loo, often just dry retching. As one of its common side effects is restlessness and muscle spasms , they didn"t help with the sleeping either ( not everyone gets same side effects of course )
Cyclizine – at round 2 when we said how bad the nauses was, they also prescribed this drug and suggested the metaclopramide was taken in addition for the first seven days. This is an antihistamine often used for sickness that combines well with other drugs – this one one didn't work at all for him, still had sickness after the steroids stopped and same problems at night.
Levemopromazine ( Nozinan) – round 3 and a new prescription to add to our growing medical chest . Again in combination with metaclopramide, this stopped the dry retching in the morning , although had terrible effects on his moods , he veered between aggression and zombiedom.
Round 4 – here we found taking metaclopramide for 9 days , but restricting it to morning and afternoon, at double the initial dose after discussions with the oncologist , reduced restless leg syndrome side effect and stopped actual vomiting but still left him feeling very nauseous for those first five days after the steroids stopped.
Round 5 – still taking the metacopramide, twice a day for the first 7 days, but supplemented with levemopromazine at night . Strangely this time, the mood swings are much less, still can be a bit dopey during the day , but worth it as totally removes nausea at night , stops the dry retching and improves his sleep. Have kept this one going for a full two weeks and is best he has felt . looking to stop this now and go to no drugs other than the Folic Acid for the final week.
Fingers crossed same combination works as well for round 6 .


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Term: So Mote It Be
So Mote It Be: An ancient phrase that means "so must it be." Originally used in Freemasonic rituals, it has been adopted for use in modern Wiccan and ceremonial magick rites where it functions as an ending or "seal" (to keep in the power) of a section of a ritual or of the entire ritual. This is similar to the use of "amen" at the end of prayers.
Druidism can be used synonymously with the phrases Celtic religion and Celtic magic. In order to enter into this magico-religious system, a familiarity with mythology is necessary. Celtic mythology is best represented in the Irish Book of Invasions ... Relevance: 100% Shamanic healing often employs plants to good effect, though it is rarely about herbalism, per se. Indeed, most shamans are explicit that the pharmacological properties of the plants they employ are of far less importance than the spirit which is ... Relevance: 100% Modern rune rituals are sometimes done entirely with visualization - the runes are made in the astral world and are never actually written down or carved on any material. This technique works fairly well, but it is not in harmony with the ancient ... Relevance: 100% Summary: If you are a collector, either of fine artwork or of Tarot decks, this is an excellent addition. If you are fascinated by the Arthurian myths but don't know too much about them, this deck, combined with the book included in the set, ... Relevance: 100% Summary: Not a beginners deck, the energy and passion in the art, combined with a unique focus on the Enochian system that only loosely—very loosely—follows standard Tarot protocols, make this deck a powerful addition to any magickian's toolkit, ... Relevance: 100% Summary: A complex deck that can lead to intense readings by intermediate and advanced readers, it is also appropriate for those following Kisma's Faery Wicca tradition. The Irish names will take dedication to master, but the usefulness of extra ... Relevance: 100% By now you may be impatiently asking yourself what ritual magic is, and how to perform it. I want to point out before beginning that it is impossible to fully describe such an extensive subject in this small essay. That is why so many excellent ... Relevance: 100% Summary:A unique and masterful blending of three of the most important Tarot decks, with beautiful and symbolic art. Highly valuable and usable by new and experienced Tarot workers.
Name of deck: Lo Scarabeo Tarot
Publisher: Lo Scarabeo
ISBN: ... Relevance: 100% Summary: The Initiatory Tarot of the Golden Dawn is an evocative and provocative deck exploring a new vision of tarot that is fresh and exciting while remaining consistent with the Golden Dawn tradition. This deck would be suitable for someone with ... Relevance: 100% I recently heard a wonderfully simple definition of the word shaman.
It was: "A shaman is one who helps people in their dealings with the other worlds."
These other worlds are the realms above, beyond, and deep within the experiences of our lives. ... Relevance: 100%
Everyone learns best by doing. The ritual
described below is representative of the rituals worked in modern magic. It
should be used as a general pattern indicating the essential elements and
sequence of rituals, and will also, I hope, be of ... Relevance: 100% |


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Vermont Reads: The Literature Of War
05/17/12 12:00PM By Jane Lindholm
 MP3  |  Download MP3  |
Many of us first learn about war by reading about it, in stories and novels, poems and memoirs. Often in school. As part of VPR's weeklong series, Vermont Reads Bull Run and The Red Badge of Courage, we look at how war is written about in literature, and what we can learn about the experience and the truths of war by reading about it with Lea Williams, an associate professor of English at Norwich University who specializes in war literature, and Peter Gilbert, the executive director of the Vermont Humanities Council.
Also in the program, the autism insurance measure that Gov. Peter Shumlin signed into law on Wednesday. Attorney Claudia Pringles explains how requiring insurance companies to provide coverage for autism will help families whose children need care.


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Since nobody answered my thread, I'll post this again. Hopefully, somebody will see it this time. I really need your help!
In an incredibly lucky event, i stumbled upon the official ultrasone importer for my country. The HFI 550 is 73 euros, the HFI 650 is 77 euros and the Proline 550 (this is an old model from what i've read) is 106 euros. I also sent an email to them asking about the prices of the HFI-580 and the HFI-680, but i doubt i'll get them for less than 130 euros.
I already did some digging and I found out that for my needs (hip-hop /electronica/ some gaming) and specs (xonar DG), the hfi-580 would be ideal. But iirc the HFI-550 should be very simillar sound-wise.
Now for my question: Should i try and gather some more money for the 580/680 or should i buy one of the ones already available? I'm on a pretty tight budget, but if it is worth it, i won't cheap out.
For referece, the HFI-580 runs at ~150 euros in my country.


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Vulnerable Extensions List 0210
(Redirected from Vulnerable Extensions List 0210)
February 2010 Reported Vulnerable Extensions
Please check with the extension publisher in case of any questions over the security of their product. Report Vulnerable extensions either in the jforum:432 security topic clearly marked with the first word in the title being Vulnerable Report where the security moderators or JSST team will respond. For a guide to the codes
Extension | Details | Date Added | Extension Update Link & Date |
Jvideodirect |
SQLi | Jan 29 | Not Known |
JEvent |
SQLi | reported Jan 29 | fixes in version 1.5.3.b |
Item3 |
3a | 3b | 3c |
Item4 |
This list is change protected, for updates or additions Mandville or lafrance
Codes used
SQLi - SQL injection wikipedia
LFI - Local File Inclusion scribd
RFI - Remote file inclusion wikipedia
DT - Directory Traversal wikipedia
Developers - How to get yourself removed from the from the VEL
Resolved items will be removed after a suitable period and not on resolution
Please solve the issues and:
- If JED listed
Attach the new zip file at your actual JED listing.
Change the extension version at JED listing.
Contact the JED by mail with a notice and ask them republish your listing.
- If not JED listed.
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- 12-15-2012, 06:20 PM #1Member
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concatenate command-line arguments as strings
I have a problem to solve and im not to sure how to go bout it.
the program needs to do this :
java Concatenate xyz abc uvw
"xyz abc uvw"
at command line.
I need to use two functions in order for it to produce the concatenated strings and another function to put the command line arguments into " ". This is a very simple program but im new to programming and need some pointers about how to solve this.
first post.
Re: concatenate command-line arguments as strings
If you're forever cleaning cobwebs, it's time to get rid of the spiders.
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Return to program book search
Date: Sunday, March 23
CME Credits: 2.00
Location: Room 704/706
Time: 3:30 PM - 5:30 PM
Director: Lyn M. Duncan, MD - Handout
Learning Objectives: Following this course, the attendee should be able to:
Description: Prompt and accurate diagnosis of vascular injury has important clinical implications. The histopathological features of thrombotic vasculopathy and vasculitis in the skin will be described with an emphasis on clinical pathological correlation and the interpretation of laboratory results. Topics will include warfarin-induced skin necrosis, hypocomplementemic urticarial vasculitis, Remicade (infliximab)-induced vasculitis, cocaine/Levamisole-associated thrombotic vasculopathy, septic vasculitis and purpura fulminans.


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Savannah Wedding from Ariel Renae Photography
When a wedding like this comes along, it's like a gift from the wedding gods. A crazy amazing gift that grabs ahold of your heart and never lets go. Because this isn't just any wedding. It's a day filled to the brim withView Credits
Read More


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Old Slave Mart Museum
Once part of a complex of buildings, the Slave Mart building is the only structure to remain. When it was first constructed in 1859, the open ended building was referred to as a shed, and used the walls of the German Fire Hall to its west to support the roof timbers. Slave auctions were held inside. The interior was one large room with a 20-foot ceiling, while the front facade was more impressive with its high arch, octagonal pillars and a large iron gate. In 1938, the property was purchased by Miriam B. Wilson, who turned the site into a museum of African American history, arts and crafts.
Other Historic sites in this state by Type | ||
Architecture, Historic | Battlefields | Buildings, Historic |
Districts, Historic | Forts & Military | Homes, Historic |
Living History | Monuments & Memorials | Museums |
Plantations | Presidential Sites |


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Does anyone know if it's possible to get input from a playstation controller whilst still having that input go through to the console? The idea being you could play a game normally whilst also controlling musical paramters. What would this need?
I think the solution is not straightforward. You need to dive into electronics a bit for that.
If you have a wired controller, then it will be powered by the playstation. You can't just "tap into" that circuit. One option could be to wire low-resistance opto-couplers (http://en.wikipedia.org/wiki/Opto-isolator) into the signal cables and connect a 2nd circuit board like an arduino (http://www.arduino.cc) to it. To put it simple, an opto coupler could be seen as a "signal duplicator".
Check the arduino site, they have a section on psx controllers: http://www.arduino.cc/playground/Main/PSXLibrary
If you have a wireless controller, then I really wouldn't know…
Hope this can help you further.
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Digestive Disorders |
Pressure in Abdomen09/27/2011 |
After eating I have pressure in my abdomen on the right side just below the rib cage. It feels like something is pushing from the inside. When pushed on it feels rigid but goes away after about an hour but I still feel that that spot feels a little rigid and when pushed on can feel something in that area.
It is hard to say what this is without examining you. It could be as simple as slowed stomach emptying, dilation of a loop of the colon, or bowel to gallbladder detention. If it's bothering you, I would advise a visit to your doctor for an exam.
D Roy Ferguson, MD Associate Professor of Medicine School of Medicine Case Western Reserve University |


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Robert Lee Mingie (above) of Owenton, received the Champions of Character Award for Men's Indoor Track at Campbellsville University's Honors and Awards Day, April 17 in Ransdell Chapel.
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How to play Pwong Game
Rules are simple. Hit all balls back to the other side. Whenever you miss a ball your score gets decreased, and whenever your opponent misses a ball your score gets increased. The more balls are in play, the less it counts if you miss one. Move your paddle with the mouse. Click to shoot when you have ammo loaded. Press "P" to pause and "M" to mute.
Pwong game controls
M = Mute;P = Pause;fire = left_mouse;jump = na;movement = mouse;
Game Description
Pwong will challenge your pong skills to the max. Can you handle up to 20 balls at once and rank as the ultimate "Pwong Pwner"? Choose from three different difficulties all with stunning graphics and high quality music. Easy to learn, but hard enough to master. Pwn that crazy AI, with your mad pong skills!


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The TLS at the Chelsea Flower Show
Briefly to the Chelsea Flower Show: where I had learnt that there was a 'literary garden'.
There was a picture of it in the office when I was picking illustrations for the TLS this week. Every other newspaper seemed to have its own garden at Chelsea. So why not the TLS? We could adopt a garden It would need only to be a small one. Not, I think, however, this literary garden - despite its Cornus Kousa tree called 'China Girl' and geraniums called 'Jolly Bee'. The lettering on wood and slate was magnificent; the literary was not. But then I thought of the arguments that we would have to have at the TLS about what words would be most truly worth the skills of master carver, Martin Cook. Donne vs Dryden. Shelley vs Shakespeare. Our own poets vs each other. Enough, enough. No sponsored horticulture for us. Time to move on — to the 'show gardens', larger constructions sponsored by DIY chains as well as newspapers, financial power-houses and northern cities where water was once the important source of power. Crowds gathered five deep around a 'gold medal winner' based, it was said, on Roman ruins in a city of eastern Libya, one now judged to be in the good part of that benighted country. No one seemed to know why they were looking so keenly. The relationship to Ptolemais was not as evident as I had hoped. The beauty was said by some to be something to do with parsnips. Inside the main tent there were flowers shown without the assistance of human invention. There were walls of daffodils, squares of grasses, bamboo groves, parade grounds of delphiniums and lupins,; and there was a bright giant lily called Nuance (surely an irony that would have graced a truly literary garden) whose bulbs were for sale at £5 for three (from www.hartsnursery.co.uk). Two packs have come home here tonight. Maybe they will produce their pink-striped bigger-than-any-lily-I-have-ever-seen blooms in Primrose Hill as well as Chelsea. More likely they will not. It is an axiom hard to deny that gardening is all about hopes and dreams. The greatest proof of visitors' rejection of gardening reality was the sight today of all the lawn-mower sellers, keen men in brazen sun glasses, keen women in black pencil skirts, all of them ready to sell cutters of grass at unrepeatable cut prices, all of them reminders of gardening as it is, all of them avoided like blight.


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Pat Nemechek avait besoin d'un nouveau design de Tee-shirt et a lancé un concours sur 99designs.
Un gagnant a été sélectionné de 157 designs proposés par 57 designers freelance.
Carb is a 4 Letter Word!
I am an Internal Medicine doctor who aggressively utilizes nutrition to treatment my patients with hypertension, diabetes and heart disease. Many patients feel that changing their life style is nearly impossible and unpleasant to boot. I want a logo that will inspire and remind them to eliminate carbohydrates from their life. I'm somewhat of a jokester with my patients and have a very relaxed communication style. I'd like the logo to be somewhat lighthearted and remind them it can be fun and adventure to reduce carbohydrates and become healthy again.
The audience is probably men and women from 30-60 years of age who are more interested in becoming healthy than taking another medication.
This isn't necessarily a dieting type of person. We focus more on reducing carbohydrates than reducing weight.
I need file type that would be used both on the web and for print. I don't know specifically what these are but the most common type from your perspective will be fine.
You are completely free to emphasis the slogan, "Carb is a 4 Letter Word!" I would like people to think it is fun to wear a hat or a shirt with this logo on it.
You can see my practice website http://www.healthrenewal.org and my nutritional blog website http://www.healthrenewal.org/nhrblog if you want to get a general sense of things.
Also, I'm not completely wed to the basic colors of my logo.


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UH Manoa Campus Events Calendar
UH Manoa Student Voting Drive
April 23, 2012 - May 3, 2012Manoa Campus, Various
Students are chronically underrepresented in the electorate and their concerns are therefore marginalized in state and local policy. We want to change this in Hawaii, and are calling for instructor and student help to begin changing the culture on this campus.
We are asking faculty to dedicate 15 minutes of class/meeting time during the week of April 23 to May 2, to have students register to vote. We have trained volunteers who can come to your class, answer student questions, and register them to vote. The entire process will take 15 minutes.
Please take a minute now to complete a brief online request at http://kanu.me/uhvotes
and we will send a volunteer to your class/meeting. Please send requests by the deadline of Wednesday, April 18.
If you would like to have this service in your classes, we encourage you to speak with your instructors and ask them if class time can be spared for voter registration. If you are interested in volunteering to help us in this effort, we would love to have you.
The time commitment is small: a training session on Thursday, April 19 at 5:30 in Kuykendall 410, followed by signing up (based on your schedule) to visit a few classes or to register your own classes. Please contact email@example.com by Wednesday, April 18.
April 19 (Thursday)
Kuykendall 410
5:30-6:30 p.m.
Bring a friend!
This voter registration drive is being conducted in partnership with Kanu Hawaii, a nonpartisan, nonprofit organization that is committed to expanding civic engagement, and with the support of The Value of Hawaii hui.
If you have additional questions, please contact email@example.com. We appreciate your time for this important civic service during this busy part of the semester.
Mahalo nui!
Kanu Hawaii, The Value of Hawaii hui
Event Sponsor
Center for Biographical Research, Manoa Campus
More Information
808-358-0871, email@example.com, http://kanu.me/uhvotes
Wednesday, May 2 | |
12:00pm |
Micr 690 Seminar
Manoa Campus, Business Administration C101 |
12:30pm |
East-West Toastmasters Public Speaking Club Meeting
Manoa Campus, Sinclair Library 201 (Learning Arena 2) |
3:00pm |
Mathematics Final Oral
Manoa Campus, Keller Hall Room 403 |
3:00pm |
WRRC Seminar - Halorespiration, a natural process
Manoa Campus, POST 126 |
3:30pm |
Manoa Sustainability Corps Monthly Meeting
Manoa Campus, Hawaii Inst. of Geophysics (HIG), Room 210 |
5:00pm |
Business Night
Sheraton Waikiki - Maui/Kauai Ballroom |
- Highlighted dates have scheduled events.
- Select the date to view all events for that day.


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Coats & Jackets
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Timberwolves are looking for big things this season
Tualatin, with a strong group of returnees, is hoping for good things in the 2006 season
TUALATIN - Tualatin High School boys soccer coach Eric McClellan knows he has a special group this season.
The Timberwolves have all the makings of one of the state's top teams: senior leadership, talented playmakers, aggressive rock-solid defenders, experienced keeper.
Tualatin graduated just one starter, albeit Pac-9 co-player of the year Reid Phillips, leaving a senior-heavy crew determined to improve on last season when the team finished third in the Pac-9 Conference at 5-1-2 before being knocked out of the state playoffs in the second round.
'We'll have a solid team this season,' said McClellan, who is in his fifth season as Tualatin's head coach. 'The core is here. We've been planning for this the last two years. Teams like this don't come around very often.'
Senior Jarad VanSchaik is reason No. 1 of many for the Timberwolves' optimism. McClellan considers VanSchaik one of the 'top three to five players in the state.' The 6-foot-1 forward was named Pac-9 all-league the past two seasons and brings a complete game to the field.
'His skills are very tight,' McClellan said. 'He can do it own his own or lay it off. He's a player you love to have. He's unselfish. At times I wish he was actually a little more selfish. He's that good.'
Fellow captain Kyle Wallace moves up from defender to the midfield and provides heady play and leadership. The junior was second team all-league last season.
'He's a very aggressive player,' said McClellan. 'He doesn't shy away from tackles. He'll keep us organized and our heads in the game.'
Jeff Wheeler also will be moving positions after earning all-league honors as the Timberwolves' stopper last year.
The senior will move to sweeper where he'll use his strong frame to dominate control of the 50-50 balls.
'He's just heady,' McClellan said. 'You can depend on him to come out with the ball nine times out of 10.'
Senior Todd Philips further strengthens Tualatin's defense in his third year at the varsity level.
'He's another solid defender who likes to attack out of the back,' McClellan said. 'By putting him on a guy, I know he'll be marked out for the game.'
For all its experience, the Timberwolves will also receive an influx on younger talent led by sophomore midfielder Marshall Atmore.
Atmore responded well when McClellan moved him into a starting role for the playoffs last season after playing most of the fall at the junior varsity level.
'He has the ability to come in and be a big key for us,' McClellan said. 'He's young, but he has the talent to do some big things.'
Junior Gabe Tatz returns for his third year in the net for the Timberwolves. He was all-league honorable mention keeper last season.
Senior Jake Howard will likely back up Tatz again, but he has been pushing for playing time.
'I expect anyone we plug in there, with our defense, to have confidence,' McClellan said. 'And our defense will have confidence in them.'
McClellan considers defending league co-champions McMinnville and Tigard to provide the biggest challenge to their conference title hopes.
He also added that Forest Grove, who each tied Tualatin last season, is a threats in what should be another competitive league schedule.
'Each year it seems like it comes down to the last one or two games to determine the playoffs,' McClellan said. 'I don't see anything different this year. It will be a battle 'til the end.'
Tualatin got its season off to a winning start, opening up with a 4-1 home win over Woodburn in a non-league match played Tuesday.
The Wolves will be back in action tonight when they play at Southridge in non-league match starting at 7:30 p.m.
On Tuesday, Tualatin will be home to face Sunset at 7 p.m.


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on orders of $85 or more
An excerpt from www.HouseOfNames.com archives copyright © 2000 - 2017
Herewod Early OriginsThe surname Herewod was first found in Lancashire at either Great Harwood or Little Harwood; and or in West Yorkshire at Harewood, all villages. [1]CITATION[CLOSE] Bardsley, C.W, A Dictionary of English and Welsh Surnames: With Special American Instances. Wiltshire: Heraldry Today, 1901. Print. (ISBN 0-900455-44-6) Herewod Spelling VariationsHerewod Spelling VariationsThe English language only became standardized in the last few centuries; therefore, spelling variations are common among early Anglo-Saxon names. As the form of the English language changed, even the spelling of literate people's names evolved. Herewod has been recorded under many different variations, including Harwood, Harewood, Horwood, Whorwood, Herwood, Hereward, Harward and many more. Herewod Early HistoryHerewod Early HistoryThis web page shows only a small excerpt of our Herewod research. Another 207 words (15 lines of text) covering the years 1071 and 1600 are included under the topic Early Herewod History in all our PDF Extended History products and printed products wherever possible. Herewod Early Notables (pre 1700)Herewod Early Notables (pre 1700)More information is included under the topic Early Herewod Notables in all our PDF Extended History products and printed products wherever possible. Herewod In IrelandHerewod In IrelandSome of the Herewod family moved to Ireland, but this topic is not covered in this excerpt. Another 39 words (3 lines of text) about their life in Ireland is included in all our PDF Extended History products and printed products wherever possible. The Great MigrationThe Great MigrationFor many English families, the political and religious disarray that shrouded England made the far away New World an attractive prospect. On cramped disease-ridden ships, thousands migrated to those British colonies that would eventually become Canada and the United States. Those hardy settlers that survived the journey often went on to make important contributions to the emerging nations in which they landed. Analysis of immigration records indicates that some of the first North American immigrants bore the name Herewod or a variant listed above: Robert and Thomas Harwood who settled in Virginia in 1635; followed later by George Harwood in 1643. Herewod Family Crest ProductsHerewod Family Crest ProductsSee AlsoSee AlsoCitationsCitations
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The Herewod Family Crest was acquired from the Houseofnames.com archives. The Herewod Family Crest was drawn according to heraldic standards based on published blazons. We generally include the oldest published family crest once associated with each surname. This page was last modified on 20 November 2015 at 13:32. Sign Up
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If you believe that not proving the theory false is MOSTLY proving it true, then you are right. To my knowledge, Einstein did not know of black holes. true Relativity holds up if it is comprised of mass so great that not even light can escape. But if it is ever found to be something different, then Relativity will surely have to be modified. Even today, scientists are constantly testing it. Don't you think that is good. Or should we just call such science "junk science"? As to it's complexity, I remember the theory of the ATOM in 1961 when I was a freshman in college. Is the theory the same today as in 1961? No it is not. Does that mean that the theory was false in 1961? You can make that judgement for yourself.
In 1961, I can't remember the exact number of elements that was supposed to comprise the universe but I do know that there are more today. Since these theories have had to be modified,does that mean that they are both more complicated than the THEORY of Relativity?
Maybe we could keep it simple. When does human life begin? When does it end? Simple? Maybe, but we STILL don't have a FACTUAL answer. When I went to college, one was taught to QUESTION, to CHALLENGE, to BE SKEPTICAL. That was the basic precept of science. Now today we talk about "junk science", "end of discussion", theory is now to be taken as FACT, discussion not allowed.
As to income redistribution, do you not call corporate welfare(solar and wind production and purchasing, ect), food stamps, student loans, housing subsities, heating subsities, ect, income redistribution? You even have a thread talking about the distribution of income. In a market based capitolistic system, people have the right to FREELY exchange their doods and serivces. Income is just a medium of exchange to facilitate that RIGHT. Yet you seem to speak of it as if income distribution is something other than that.


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industrial strength outdoor ivy and vines |
Our product is an environmentally friendly, artificial ivy and vine system designed to prevent the lure of unsightly graffiti. Ivy-It™ creates a realistic and aesthetically true representation of natural foliage. Please feel free to browse through our website to become more familiar with how municipalities, home-owners and property managers/owners can benefit from the advantages this unique product offers. Contact us to learn how truly simple and practical these products are and to request an estimate or more information. |
Graffiti deterrenceHow can we help you deter graffiti?Info |
Privacy & beautificationHow can we help you?Info |
©2009 Ivy-It™, Inc., Claremont, CA. All Rights Reserved | phone 909.447.0469 | email site by DoctorGeek |


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CH391L/S13/Phage Therapy
From OpenWetWare
Contents |
Introduction to Phage Therapy
Phage therapy is the use of viruses to treat bacterial infections. Application of bacteriophage to a bacterial infection will result in the phage infecting, replicating, and then destroying their bacterial hosts. The newly synthesized phage can then go on to infect other bacteria, resulting in the rapid removal of the infection. The use of phages to treat bacterial infections has received new attention due to the appearance of strains of previously treatable pathogens such as methicillin-resistant Staphylococcus aureus, and multidrug-resistant tuberculosis.
The discovery of a bacterial-killing substance that could pass through extremely small filters was observed independently several times[1]:
Year | Discoverer, country, microbe sensitive to phage |
1896 | Hankin, British, Vibrio cholerae |
1898 | Gamaleya, Russian, Bacillus subtilis |
1915 | Twort, British, Staphylococcus |
1917 | d'Herelle, French-Canadian, Shigella |
The first therapeutic usage of phage was in 1919, to treat a child with severe dysentery. In a classic case of old-school science, the lead researchers (which included d'Herelle) drank portions of the bacteriophage preparation the day before treating the child, to check the treatment's safety in humans. The researchers didn't keel over, the child fully recovered within a few days, and further tests on other patients confirmed the result.
In the 1930s and 1940s, bacteriophage preparations were developed and sold by major companies such as L'Oréal and the Eli Lilly Company. The development and mass production of antibiotics in the late 1940s halted research into phage therapy in the West, due to the efficacy of antibiotics. Research continued in the Soviet Union. Hundreds of studies were made on phage therapy, with the the largest carried out in Tbilisi in 1963-64, involving 30,000 children [1]. This study focused on the use of phage as a weekly-administered prophylactic against Shigella. The incidence of dysentery was 3.8-fold higher in the placebo group, and there was a 2.3-fold decrease in diarrheal diseases of unknown origin in the treated group. These results are impressive, but many other studies lacked controls, weren't blinded, or omitted crucial data such as the number of subjects treated in a study. Combined with the lack of knowledge transfer during the Cold War, and the publication of these studies only in Russian, prevented advances in the Soviet Union from influencing research in the rest of the world.
Current Applications
Regular use of phage therapy occurs primarily in the Republic of Georgia, due to the presence of the Eliava Institute, which has research phage therapy since the 1920s. However, synthetic biology has enabled entirely new approaches to phage therapy, such as engineering new abilities into the phage. One such ability is the degradation of the extracellular polysaccharides (EPS) produced by bacteria during infections[2]. Production of the EPS results in a biofilm, which protects the bacteria within from external harm, such as antibiotics and bacteriophages, limiting the damage to the cells on the surface. To break through this barrier, researches inserted the gene for DspB, an enzyme that degrades one of the key components of EPS. After bacteria on the surface of the biofilm are infected, they produce DspB along with new phage. After the cells lyse, the DspB can degrade the EPS, which exposes more bacteria to infection.
One concern of phage therapy is the rapid lysing of pathogenic cells which may contain endotoxins. Sudden, masssive releases of toxin can cause dangerous amounts of inflammation. Therefore, phage that kill the targeted pathogen without disrupted the cell's integrity are of interest. This can be accomplished by that by modifying phage to express endonucleases and holins, which are toxic to the cell (chopping DNA and making non-catastrophic disruptions to the cellular membrane)[3]. Toxin release was minimized, which decreased inflammation and increased the survival rate of treated mice.
Phage therapy can also be used in conjunction with antibiotics. This is especially useful when trying to avoid quickly evolving resistance to the phage being used. In this approach, the antibiotics provide the killing blow, while the phage assist by suppressing gene networks that are not directly impacted by the antibiotics. One example of this was the combination of ofloxacin (which damage DNA, proteins, and lipids) with phage suppressing the SOS response, which repairs damaged DNA. M13 phage were engineered to overproduce LexA when infecting E. coli, which prevents the SOS response from occurring.
Two teams in 2008 had similar approaches to modifying phage therapy: using a host that would be used as a probiotic to carry a phage targeting a gut pathogen. The goal of Team Hiedelberg's "EcoLicense to Kill" was to make a lambda phage that can transfer to a pathogen by conjugation. Once inside the pathogen, the phage would immediately begin replication (due to knocking out the lysogenic cycle of lambda). The pathogen is killed, and phage are released to infect more target bacteria, while leaving the original host (the "killer") unaffected. Team Caltech used a lamB- strain of E. coli that had lambda integrated into it's genome. This was a model for the future application, which could be an E. coli carrying a phage like P22, which could target Salmonella. Both teams succeeded at making proof-of-concept constructs.
Future Directions
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Error fetching PMID 11181338:
Error fetching PMID 19255432:
- Error fetching PMID 11181338:
Recent minireview of phage research. - Error fetching PMID 17592147:
Phage that makes infected cells produce Dispersin B, which degrades biofilms. - Error fetching PMID 12969496:
Describes the engineering of a phage that kills via non-lytic means, i.e. endonucleases and holins. - Error fetching PMID 19255432:
Efficacy of previously resisted antibiotics restored by phage suppressing the SOS response in host.


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Spelaeophryne Ahl, 1924
1 species
Spelaeophryne Ahl, 1924, Zool. Anz., 61: 99. Type species: Spelaeophryne methneri Ahl, 1924, by original designation.
English Names
African Striped Frogs (Frank and Ramus, 1995, Compl. Guide Scient. Common Names Amph. Rept. World: 92).
As for the single species.
Contained taxa (1 sp.):
External links:
Please note: these links will take you to external websites not affiliated with the American Museum of Natural History. We are not responsible for their content.
- For additional sources of information from other sites search Google
- For images search Arkive, CalPhoto Images and Google Images
- To search the NIH genetic sequence database, see To search the NIH genetic sequence database, see GenBank


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DOVER, Del.—More than a month after undergoing a "successful procedure" at a Texas cancer center, Delaware Attorney General Beau Biden is holding a $1,200-per-person fundraiser this weekend at the home of his father, Vice President Joe Biden.
But as he raises money while eyeing a third term as attorney general, the younger Biden is still declining to provide details on his health issues.
Biden, through his spokesmen, has repeatedly denied requests for interviews. His office also has refused to release details of his schedules and communications with top staffers before and after his hospitalization in response to a Freedom of Information Act request by The Associated Press.
The 44-year-old Democrat, who suffered a mild stroke in 2010, hasn't made any public appearances since being hospitalized after becoming weak and disoriented during a vacation last month.