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David J. McIntyre Jr.
Mr. Chairman, Ranking Member Michaud, and distinguished members of the Committee, thank you very much for the opportunity to appear before you this morning to discuss the critical topic of access to health care for our nation's Veterans – and, in particular, the use of non-VA care.
Our History
For 18 years, I have had the distinct privilege of leading a company whose sole mission is standing alongside the federal government in serving the health care needs of those who served this country in uniform and their families. In 1996, a group of non-profit health plans and university health systems came together and founded TriWest Healthcare Alliance. Our initial mission was to serve the Department of Defense (DoD) in bringing up the first TRICARE contract in what were then Regions 7 and 8. And while today TRICARE is recognized as a cherished benefit for our Service members and their eligible family members, it took many years of hard work, focus, and most importantly partnership between the contractor community and DoD's health care system to mature to this point. I am proud of the role TriWest played, along with our colleagues in the contractor community, in the implementation, maturation, and improvement of that program during our years of service in support of the Defense Department. And, I am even more proud today to have the privilege of bringing that same focus and intensity to the side of the Department of Veterans Affairs (VA) through their new Patient Centered Community Care (PC3) program.
In addition, we have the privilege of serving the United States Marine Corps as the worldwide operator of the DSTRESS stress and suicide-prevention contact center and the back-up to the Sexual Assault Prevention and Response (SAPR) line. We also serve the United State Air Force by providing appointing service in three Military Treatment Facilities in the Continental United States.
Awarded PC3 Contracts for Regions 3, 5, and 6
On September 4, 2013, TriWest was awarded a contract to serve VA in implementing their brand new PC3 program. I want to say what an honor and privilege it is to be entrusted to serve alongside VA in caring for our Nation's most deserving citizens... its Veterans! Each and every member of the TriWest family feels privileged to be of service to our nation's Veterans – from the Chairman of our Board (who is the President and CEO of Blue Cross Blue Shield of Arizona) and the rest of our 11 owners, to our senior executives, to all of our employees.
Working with VA on implementing this new program is in many ways a return to our earliest days. We find ourselves partnering each and every day with a group of dedicated public servants, working long hours to deliver the promise of access to quality health care to a deserving population. We knew standing up a new program would be challenging and consuming. But, we also knew that success in meeting the challenge meant we would have the honor of playing a part in ensuring our nation's Veterans received the care they've earned through their service and sacrifice. Because of this, we embrace the opportunity to again lean all the way forward.
Our Network, Our Focus and Our Commitment
As I just indicated, TriWest provides a diverse set of services to our military and VA clients. At our core, though, TriWest is a company that builds and maintains networks of health care providers, who agree to render care to the deserving beneficiaries we are privileged to serve at a reasonable price for the taxpayer. We then pay those providers on behalf of customers quickly and accurately while focusing intently on professional, fair dealing as the keys to maintaining that network of high quality clinicians.
Today, through the TriWest network, we provide Veterans with access to nearly 70,000 specialty providers and facilities throughout VA's Regions 3, 5, and 6 and are continuing to grow those numbers each and every day as we learn more about their health care needs. Right now, the network available in our native territory, which consists largely of the Western and Midwestern states, contain more robust availability due to how much we knew about that market and our historical presence in that area supporting the DoD. However, we have been engaging the provider community throughout the Southern and Eastern parts of the PC3 Regions for many months now and are finding providers of all types willing to come forward and serve this most deserving population. We have committed to VA that our network will be available within the access standards as well as credentialed and checked against all of VA's specialized quality requirements.
PC3: Our Tasks and Our Team
Under the terms of our contract with VA to administer the PC3 program, TriWest is responsible for:
Building a network of providers – This includes executing all contracts either in-house or in conjunction with our network subcontractors (who are indigenous to their territories of operation), verifying all licensure, certifications, and specialty designations as well as completing all credentialing work. In addition, our contract with VA contains a number of unique requirements for certain specialties and subspecialties that are needed by Veterans. It is our job to ensure those requirements are met.
Making appointments for our Veterans; ensuring they see the doctor – For each authorization TriWest receives, our staff reaches out and attempts to make contact with the Veteran to ascertain their preferred time and date of appointment. We then identify a network provider within the standards set forth in our contract and reach out to that provider and make an appointment before circling back with the Veteran to confirm. In addition, TriWest makes efforts to ascertain the Veteran's preferred communication method so that 48 hours prior to the appointment, we can send a reminder – lessening the potential for missed appointments and resulting in the delivery of the needed care. Afterwards, we confirm that the appointment occurred.
In those instances in which we cannot reach a Veteran within three days to make an appointment, our contract requires that we make an appointment for the Veteran and send a letter to him or her with the appointment information. We have noticed a not insignificant higher percentage of missed appointments when using the letter method, and have discussed this matter with VA officials.
Following-up after appointments to retrieve medical documentation to return it to VA – Ensuring that a Veteran receives timely access to a high quality health care provider is certainly the most important element of the program. However, following the delivery of health care it is important to make sure that a report from the provider rendering the care gets returned to the Veteran's home VA facility in a timely fashion so that it may be placed in the medical record of the Veteran. And, it is our responsibility to ensure that such occurs. This helps make certain that any findings, recommended treatments, or other important clinical services can occur with full knowledge of the episode of care that occurred in the community.
Paying the providers' claims – As I mentioned earlier, TriWest knows that without our providers, we cannot deliver care through the PC3 program. We realize that sometimes the federal reimbursement rates aren't always the most attractive rate in the marketplace. However, we have learned that timely and accurate payment of claims goes a long way towards ensuring that a provider stays in the network and continues to see our deserving Veterans. Our providers are patriotic and dedicated. But, we do need to recognize their professional value by paying them on time.
To accomplish all of this work, we rely on our dedicated team who work either in our corporate headquarters in Phoenix, AZ or our call center located in Puyallup, WA. In fact, I am pleased to tell the Committee that in an effort to be certain we are ready and able to assist VA in working down their identified backlogs for care, we recently doubled our front-line staff with the hiring of 100 new employees. They will be joined by another 100 or so next week. All of them will be trained and ready to serve VA and our nation's Veterans in the very near future, giving us the ability to meet the coming demand from the clusters of backlogs across our geographic area of responsibility.
Non-VA Care and the First Five Months of PC3
Implementation work "behind the scenes"
As noted earlier, TriWest was awarded the PC3 contract on September 4, 2013 and we officially began implementation of the program on September 26, 2013. Most of the early work consisted of "behind the scenes" efforts in coordination and cooperation with VA. Under our implementation plan, we would begin direct services to Veterans in Region 5 January 2, 2014 while rolling-out services to Regions 3 and 6 on April 1, 2014.
I would like to say at this time that I regret that our implementation schedule in Region 3 needed to be pushed back from the original April 1 date to allow for a phased implementation through June 30 to allow more time to ensure that we had the right providers available to VA when authorizations for care were sent to us. We had a robust network in many places throughout the Region; however, we expected to have many more providers than we did in some of the geographically diverse places to serve VA's needs. Since that time, we have been working around the clock to sign up additional network providers. And, as we do so, we are constantly updating VA on a location-by-location and service-by-service basis so that local officials know what is available. We expect to be at or near completion of our initial building goals by July 1, 2014. And, in the midst of it all, we have now been working to address the clusters of backlogged care that have materialized… making the challenge a bit more complicated.
During our "behind the scenes" implementation TriWest worked simultaneously on a number of initiatives, including:
Ramping up our network building – While TriWest maintained a sizable network from our previous TRICARE work, upon award of the PC3 contract, we began in earnest the work required to amend those contracts to meet all of VA's standards.
Developing our TriWest/VA portal – This interactive portal system is used by VA employees to enter authorizations for care; track when care has been scheduled or provided; and monitor the return of medical documentation related to an appointment in the network. The portal is also used by TriWest staff to upload medical documentation in .pdf format for return to VA and also to enter Secondary Authorization Requests, which VA can then consider and approve for service in the network or appoint to its own facilities.
Developing our TriWest Provider Portal – This interactive portal allows network providers who see Veterans under the PC3 program to view authorizations; upload medical documentation; confirm appointment timeliness; and make a Secondary Authorization Request.
Standing up our contact center operations – In a short period of time we had to acquire building space, bring in Information Technology (IT) services, and hire the staff that would begin serving Veterans in Region 5 on January 2, 2014.
Training hundreds of TriWest and VA staff – The PC3 program was not only new to TriWest and our recently-hired staff, but many aspects of it were also new to employees of the non-VA Care Coordination offices in VA Medical Centers (VAMC) all across the Regions. Working closely with our VA team colleagues in the Project Management Office, we provided unique user names and passwords for all of the VA staff at facilities across Region 5 and trained them of the use of the portal.
Conducting Site Visits – On these visits, which were coordinated and led by our VA Project Management Office colleagues, we introduced ourselves and worked to educate VAMC staff and leadership on the elements of the PC3 contract and the tools we had and how TriWest would interact with them to serve Veterans.
Start of direct care delivery
On January 2, 2014, fewer than four months after award, we went live and began direct services to Veterans throughout Region 5. Not surprisingly, as a new program, PC3 started slow. During the first few months, we were receiving on average about 100 authorizations each day from the VAMCs we serve; although the daily number fluctuated from between 30-150 each day. That workload translated into about 2,000 authorizations for care during the month of January. I can state, unequivocally, that slow initial start is now a very distant memory for all of us in our geographic area of responsibility… TriWest and VA team alike… in spite of the short timeframe since we started delivering services.
In February, workload inched up slightly from 2,000 to about 2,500 for the month. For the month of May, we received 10,000 authorizations for care – a quadrupling of the monthly volume in just three months. And we expect the growth to continue. I will talk shortly about how we are preparing for that growth.
Perhaps, as to be expected with any new program, not everything has gone according to plan during the first couple of months. First, as noted above, we know that despite our best efforts, not all of our network was ready in all of the places where we needed to have it in order to best serve VA's and Veterans' needs. The reasons are varied and several-fold: immaturity of data, complexity of contract requirements, Medicare-based reimbursements rates, VA's continued provider engagement separate and distinct from the PC3 program; and lack of clarity of all of the places in which care was going to be needed and the volume of such care… exacerbated a bit by the current clusters of backlogged care. But, whatever the reasons, they are only reasons and not excuses. It is our job to have services available and we will meet that expectation. And, I am pleased to state that in spite of these initial challenges, together we are gaining on it.
As you might expect, in a personnel-intense program, the rapid increase in workload from February to May led to some delays in appointing Veterans within the desired timeliness standards. Fortunately, as I noted earlier, in less than one month, we have been able to hire nearly 100 new staff. That growth in staffing has substantially cured those challenges. And, we will be adding another 100 this next week. That said, I would be remiss if I did not note that while TriWest certainly welcomes the rapid growth in the use of the PC3 program, the Indefinite Delivery/Indefinite Quantity (IDIQ) contract design can present some unique challenges when such a rapid and voluminous change in demand comes into play.
From a taxpayer-centric approach, VA does not wish to pay for services until after they are ordered. This is certainly understandable. And, with this contract design they do not have to. Yet, paying in arrears with little information on projected ordering volumes means TriWest is estimating the need for physical space and staff with little information or experience on all sides. As such, rapid growth could – and did for a bit – overwhelm TriWest's infrastructure and staff that was built without foreknowledge of the clusters of backlogged care that existed. But, together, we, and the VA team in our geographic areas of responsibility, are persevering and I believe that we have prognosticated well enough to have a reasonable probability of positioning ourselves to successfully meet the demand when it arrives.
Please know that I am in no way advocating for a change in contract design. I am only noting the importance of sharing information between VA and the PC3 contractors in a design like this so that we can reasonably predict the workload we will be facing in advance and be better prepared to respond to it. And, I am pleased to report that VA has done a very solid job of responding to that need once we all got visibility of the clusters of backlogged demand for care.
I would also like to note that we have received a lot of feedback on our TriWest/VA Portal interface tool from VA staff and our Contracting Officer. We have listened and made substantial upgrades and improvements in recent months. These changes will not only enhance productivity and efficiency inside TriWest and VA, but they will also provide valuable data tools for all of us to use in monitoring our progress and the experience of receiving care through the PC3 program.
Finally, Mr. Chairman, I would like to spend a minute discussing how TriWest is partnering with the VA team to address the current access challenges faced by many of the VAMCs in our areas of geographic responsibility.
VA has discussed publicly its Access to Care Initiative. But, before the initiative even had a name, our colleagues in many VAMCs around the Regions we serve were reaching out to us to see if we could help, and if so, where and how fast. Our company is headquartered Phoenix AZ. And, while I realize much remains to be learned and understood about actions that occurred in Phoenix, I can say without hesitation that the leadership there today, their superiors, and the Program Management Office, have been collaborating with us each and every day to hone a model of partnering to work down the specialty care backlogs as quickly as possible. They have identifying their needs for assistance so that we can reasonably identify the capacity of the providers in our network to handle the care. And, indeed, the analysis of demand against capacity has been conducted there and for most of the places with backlogs across our entire service area. And, to ensure that we can handle the demand in Phoenix, my team and I have spoken with many leaders of large practices and facilities across Maricopa County. And, as you would expect, they are committed to leaning forward to help serve their fellow citizens. In fact, we expect to be receiving between 300-400 authorizations of care a day from the Phoenix VAMC and are prepared, along with our provider network, to handle them all within the access standards required in our contract.
In addition, just this past week, we began getting some of the authorizations for services needed to provide a special type of cognitive behavioral therapy. One of VA's Psychology Chiefs is in direct communication with our head of Behavioral Health Services, who happens to be a Veteran himself. They are matching caseloads with network providers' schedules and specialties so we can place Veterans with care in the community as quickly as possible with the right type of provider for their needs.
I know Members of the Arizona Congressional delegation are rightly looking for accountability for the past, but they are also focusing intently on solutions for tomorrow -- both long term and those that are available quickly to help Arizona Veterans. TriWest takes very seriously our obligation and privilege to do our part for the short term as well as over the long term. I am hopeful that the tools we have developed and this model of information sharing and collaboration becomes one that we can use not only in Arizona but all across our Region to assist where and when we can. And, indeed, that is exactly what is underway.
Remaining Committed and Focused
Mr. Chairman, and members of the Committee. I hope I have made clear in my comments today that TriWest is very committed to and indeed is working tirelessly alongside VA to successfully execute a program that was designed to provide Veterans with timely access to specialty care from community providers and community facilities when asked to do so by VA Medical Centers because they are unable to meet the need. We are growing our staff and we are collectively beginning to smooth-out the rougher edges of our operations under this new program. We are adding scores of new providers every day to our network. And, most importantly, we are communicating with our VA partners every single day to understand their needs community-by-community and Veteran-by-Veteran.
We have found a tremendously dedicated VA Management Team overseeing this contract and matching our work hours, focus, and intensity every step of the way. I don't think either of us believe that the other is perfect nor did we all think that we would be tested in this way. But, I want you and the rest of our fellow citizens to know that we have encountered a VA team that has nothing but the interests of our Veterans at heart, and I hope they know and believe the same thing about TriWest.
Working together, and armed with an open and honest dialogue between us, and an intensity to match the amazing service and sacrifice of our collective customer, I'm confident our Veterans will receive the timely, quality care they deserve.
Thank you. I will now be pleased to answer any questions that Committee members may have.


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Asheville's experienced a wave of new restaurant openings lately, and they're getting lots of well deserved press. But what about those favorites that have been serving great food in Asheville for years?
Cucina24 is one of which I speak. Chef/Owner Brian Canipelli has been welcoming locals and visitors to his open-kitchen (cucina) since 2008.
I say open-kitchen because the business end here is the very open kitchen just beyond the bar pictured above.
Fresh wood-fired-oven baked bread was cooling on the counter when I stopped in for lunch last week. Sitting at this counter, when it's clear of fresh-baked bread, gets you a a ring-side seat for watching kitchen action. There's a good view from many tables in the dining room, too.
Cucina24 decor is sleek-casual. There's the textured brick wall with what looks like a faded ad, hinting that it might have been an exterior wall at some point in history.
There are the curved bulkheads, tile, brick and wood finishes, and lots of wood left exposed (no table cloths). Love the rows of seasonings and ingredients on the kitchen wall. Don't know if they're actually color-coded to go with the earthy color scheme, but they do.
Black chairs from the front door to the bar, then switching to brown in the main dining area draws your eye and adds a little weight and sophistication.
You know how I fuss about low light for picture taking in restaurants? This time I thought I'd be so smart and sit right by a big window on this very sunny day. Too much light! I'm looking forward to taking a photography class this coming semester.
Offered on the menu in $5 or $10 portions, this salad ($5) was made with local baby greens, roasted pears, pecans and Pantaleo (goat) cheese, drizzled with a shallot & thyme vinaigrette. Loved the cheese and that the pear was roasted just enough to retain crunch. The vinaigrette pulled it all together wonderfully.
How often do you see a Golden Beet Sandwich ($9) on a menu? Actually, this brings me to an interesting aspect of Cucina24's menu. Items are not named, just listed under categories: antipasti, salad, sandwiches. It works on their lunch menu (see below) because there are so few items. If it were an extensive menu, a lot of reading prior to ordering would be required.
A BLT, but not. You could call it a BAB – Bacon, Arugula and Beet. Add goat cheese and Lusty Monk mustard and there it is. I asked for the mustard on the side so I could control the lust. What a nice mixture of mild and soft beets with meaty, chewy bacon and lusty heat all sandwiched between crusty toasted bread. Loved it! Will get it again.
This really is Chef Canipelli's kitchen (cucina). His presence is palpable, as well as physical. Chef served a few tables while I was there, including mine. His friendly, relaxed manner added to the "welcome to my kitchen" feel.
24 Wall Street
Asheville, NC 28801
(828) 254-6170

subset: commoncrawl


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Thanks for the response Noir. I'm a pretty realistic person so I definitely don't expect over night change, I am definitely more interested in a lifestyle change than a quick fix. In addition while it is sort of unfortunate that sinking your money into something is motivation... it just is. Maybe I'm just playing games with myself but I think that it would help motivate me more and keep me on track. I'll look into a gym membership and trainer and once I have a more specific idea of what I want to do I'll look for help online creating a diet. Thanks.
post #151 of 962
1/22/09 at 2:17am


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This is your resource to discuss support topics with your peers, and learn from each other.
I just bought 9900 and tried to set up email account. Even if I click Email Accounts Icon in Set up menu, it does not go through. It just freeze there. What do I do?
Hi and Welcome to the Community!!
I suggest the following steps, in order, even if they seem redundant to what you have already tried (steps 1 and 2 each should result in a message coming to your BB...please wait for that before proceeding to the next step):
1) Register HRT
2) Delete and Resend Service Books
3) Batt Pull Reboot
Hopefully that will get things going again for you!
If not, then you can try, from a PC/browser, your carriers BIS website, if they have one...here's a partial list:
If they aren't listed, you may need to ring them up and ask them for the URL.
Another alternative is to, from your BB Browser, try this url:
Otherwise, you should contact your mobile service provider for formal support and to ensure that you are subscribed, from them, to a data plan adequate to enable the services you desire.
Good luck!


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ESL tutor Steve told us on his monthly report that he found a fun, useful website to use with his ESL learner called Stickyball.net, and we thought we'd pass the word along!
"The following Website and its free downloads were very useful: http://stickyball.net/phrasal-verbs.html. Today I gave her a "final exam" which was fun with three review sheets:
Tutors, don't forget, if you ever come across any helpful websites, feel free to share them with the literacy office! We always like to learn about new resources available for our tutors and learners.


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Show it to her, Lee.
This is a pretty cool place,Lee .http://brew-ligion.com/ also Ironfire brewery is really good.I would recommend if you can meet up in Carlsbad some where nice so it not such a miserble enivorment.
Last edited by getbetter; 12-03-2013 at 08:30 AM.
If there was no online dating I'd never have dated anyone. It works for me.
the busy bee has no time for sorrow.
personally i agree that you should meet in her hood first, then maybe yours. why should both people be inconvenienced?
in addition, online dating exists for a reason. i'm sure a lot of us would love to meet people when we go out, but it doesn't always happen.
Upcoming Shows:
- Caribou @ The Fonda in Los Angeles on Saturday, February 28th
- The Replacements @ The Palladium in Los Angeles on Wednesday, April 15th
- Belle & Sebastian + Mac Demarco @ The Fox Theater in Pomona, CA on Thursday, April 16th
6x Coachella Attendee (2007 - 2011, 2014a)
Holy shit the sky has fallen. I actually went on a date. A real one. This was my first date in umm a couple of years. I met her shortly after getting into the Joint last month in Vegas for night one of Nine Inch Nails. We talked for about 45 minutes or so before the show started, she was alone and met up with people after the show started much like I did. We had a lot in common and exchanged phone numbers. I sent her a text after the show that night and then not much happened for a couple of weeks. Then about a week ago a friend who just came back from SE Asia said he had an extra vacation day and wanted to go to Vegas. Once I got there I texted her and asked her if she was free for dinner. She was hesitant at first but then made some time.
She lives in Vegas on the edge of the art district and drove to the casino I was staying at. We went to a hiking group "meet-up" with people she has known for a few years. It being a first date I think this made her more comfortable. We had a few drinks and spent about 3 hours there. After that we went to a bar she likes. We had a couple of more drinks and talked for another couple of hours. It was good. She had family in town the next day and I came back to Phoenix the next morning. I told her I would love to come back and take her to dinner somewhere quiet so we can get to know each other some more and she agreed that she would like that. We connected on facebook as much as I tried to avoid that so I gave her fair warning about my awful rants, she found it amusing.
Anyway, happy I finally had a date is all and wanted to share. I had to force myself get this far. I was full of anxiety and doubt which is the worst but I never let it show. I almost didn't even bother texting but I am at the point that I would absolutely hate myself for not trying or putting forth effort. At the very least this was long overdue practice with lots of positives to take away. I'm hoping to head back in a couple of weeks to see her again depending availablity. This was what I needed to convince me to put more effort into meeting women in general because frankly I have fear and anxiety when it comes to this stuff. Thank you booze for helping me the night I met her.
Vegas has an arts district?
Lee did you ever bang that chick?
This was one of the little routines she used for introducting me to her friends. While having a list of a few things in commong it went like this. "I work for Clark County, Mark tell them where you work" ........ "Maricopa County". "I live on the edge of the arts district, Mark where do you live"...."edge of the arts district in Phoenix".
One concern of mine was being in some "friend zone". I always land there so I was certain to make it clear whenever I could this was more than just two friends hanging out and that worked. Once she mentioned that I had "picked her up at the NIN show". Later in the night when we were alone I made it clear I wanted to take her out one on one soon and I would return just to do that and she said she would love to. She also mentioned the burn more than once so she has either done burning man or helped friends with installations. She also does a lot of those novelty runs like everyone wears a pajamas or some such.
They do. I've been there for a first Friday. They run a bus from Fremont East where part of the arts district is to the main section which is about a mile away. The one time I attended it felt about double the size of Phoenix first friday as far as geography and number of galleries participating goes.
Done. Thank you.
Hot date tonight.
idm ✦ sts
Good luck.
wow, I haven't posted in this thread in ages. I'm still with my current boyfriend that I met on a dating site, so put me in the "works for me" category. we've been together almost 2 years now and we've even gone on a few trips together (one of them being Austin for ACL). I took him to his first coachella last year, too, and that's when we really started getting close. the last few months we've kind of been living together part time and I've gotten to know his son (11) really well. since he works nights, I often get to be the kid's caregiver which has been a bit of an eyeopener for me.
Hey Passive, I live in Temecula and have dated plenty of guys from San Diego and it's really not that big of a deal. for most of my "first dates" we would meet somewhere in north county for dinner and drinks or a movie. San Marcos has that restaurant row that has served as a halfway point quite well. after the first few dates I agree with what Ivy said about meeting in each others neighborhoods since it's a better way to get to know each other. it can be fun to meet someone in a neutral area, but to really get to know them it helps to be in a place one of you are familiar with and switch back and forth. at least in my experience. my current boyfriend lives in Riverside and it wasn't nearly as convenient as San Diego since I was working down there and it's quite a drive to meet in Riverside when you get off at 5. it still served as a halfway point even though it was in my city.
like getbetter said, the Carlsbad area has lots of nice places to eat/drink and you're also not far from the beach for the beach at sunset thing.
also, I'm sure she's pretty used to driving an hour to do just about anything. living here, I always say that it takes an hour to get anywhere, but you can get almost anywhere in an hour from here...
if you have any questions about places in the area, let me know!
OKC. I've used other dating sites, but they've mostly just led to dates from hell, a few of them the kind that you have to make an excuse to use the restroom and never come back! OKC wasn't perfect, but I found the quality of guys to be far better than PoF, for example. of course, there's still a bunch of BS to sift through before you can find the people that are worth your time, so I would always exchange several messages before giving out my number and then talk to them on the phone a few times before actually meeting in person. it's worked out OK for me I guess.
OKC also makes it a lot easier to weed out weak lays.
me too! thanks!
agreed. the matching seemed to work far better than other sites, but I think my match with Cory only ended up being an 85% or something. guys that I had a better match with turned out not to be no match at all. I also like that you can go through their questions and see how they feel about certain hot-button topics.
I'll tell you one of the main reasons I chose to respond and meet my boyfriend, though. communication. He sent me a well thought out (and written!) message that addressed himself as well as responded to or inquired about things listed on my profile. that, in combination with his profile and the many messages and emails we exchanged gave me a pretty good understanding of what he was about before I even met him or spoke to him on the phone.
I could also tell that it wasn't a form letter that he sent to everyone. as a girl, I can't tell you how many form letters I'd get from guys. ugh. but at least they are better than the random hookup messages (possibly from Randy, I guess? )
I'm thinking of signing up for a pay dating site like eharmony. Has anyone here had any experience with one?
We're here to play some Mississippi Delta Blues. We're in a horrible depression, and I gotta admit - we're starting to like it.
I haven't gone on a date since forever. I live at home still NOT for reasons because I'm in financial disarray or don't have a job or anything that might categorize me as a loser, but because I moved back home a few years ago so that I could have a job (which actually fell through after the company financially imploded, so now I'm stuck at one I actually hate and didn't think I would be at for this long. My goal is to find a new job and hopefully move altogether, but these days, nothing is guaranteed.) Fast forward four years and my social life is dead as evidenced by posting this on a Saturday night. I live in a typical suburban sprawl with no major cities with a life to it within two hours of driving, everyone around me that's in my age range is either married with kids or a complete disaster and it really sucks being forced into not having a social life.
I've tested the waters of dating sites, but think OK Cupid is probably the one with the most depth to it and accuracy. Even with filling out my profile as much as I can, though, I'm afraid that because of the type of area I live in, the matches are pretty boring or look like the trashiest cast members of Teen Mom all grown up. Throw into the mix that it's really important to me that I find someone who has relatively similar interests in what the world outside would categorize as non-traditional music tastes, and it's pretty discouraging.
I have no idea what to do anymore. It's like I'm stuck in purgatory and have no idea when I'm going to be able to do more with my life other than sleep, work and enjoy my self-entertaining hobbies, but otherwise might as well not exist. I'm starting to feel like those people who you meet who are in their mid-40s and are hopelessly single is going to be me in 15 years.
You need to start with a better attitude.
My confidence and optimism has plummeted over the last few years and I'll be the first to admit that. I was more of a human when I was 25 than I am now. Life makes no sense.


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Bats bail out Jon Lester as Sox beat Tigers
Starter's big slump continues
DETROIT — For all the sound and fury over their closer crisis, the Red Sox have a bigger problem.
Jon Lester is a mess.
It says a lot about how things have gone lately for Lester that he stood at his locker here last night and took any satisfaction from a start in which he allowed five runs and was unable to complete the sixth inning. But thanks to a 17-hit barrage by the offense and staunch work from the bullpen, Lester got credit for a win in the Red Sox' 10-6 victory over the Tigers.
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Santa Run starts next week
El Dorado Hills neighborhoods will hear that familiar "Ho, Ho, Ho" during the El Dorado Hills Fire Department's 50th annual Santa Run, Dec. 17-21.
For four nights, Santa will ride atop a fire engine through El Dorado Hills neighborhoods. See schedule and route map at edhsantaparade.com. During the nightly parade, elves will collect canned food for the Food Bank of El Dorado County and new, unwrapped toys for Toys for Tots while Santa and Mrs. Claus greet everyone.
"I love meeting all the good boys and girls in El Dorado Hills," Santa said with a jolly laugh. "For those on my 'naughty list,' you still have time to make nice. A new toy or canned food donation during the Santa Run might undo that mischief you got yourself into earlier this year!"
On Saturday, Dec. 21, St. Nick, his lovely wife and cheery elves cap off their journey with a grand finale at El Dorado Hills Town Center, complete with fireworks, at 6 p.m. Fire Auxiliary members will serve free cookies and hot cocoa before the fireworks show.
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Seniorita does have a point about plushenko doing hip thrusts twice but Joubert also did hip thrusts and if a skater does hip thrusts in a program and can be used to interpret whatever they think the music Is saying or what the theme is. You act like doing choreo that gets he crowd into it and gets woos or squeals is not choreo is ridiculous. Choreo is whatever skater/coach/choreographer says it is. I brought up nonsense moves because I don't feel a lot of Nichol zeuva skaters just keep moving with moves that don't make sense. Not that it's not choreo but I'd rather choreo with posing, hip thrusts, if it adds to the program.
Well well well it's a thread about Russian Men prospects and here comes the second page of discussion whether hip thrusts are legal. Maybe one of you gentlemen could rewatch Men's competition at Ru Nats 2014 and count the number of hip thrusts, and then figure how many are there per skater. You're going to be surprised


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Chrysler aims to sell over 800,000 Jeeps in 2013 -Marchionne
GENEVA, March 6 (Reuters) - Fiat Chief Executive Sergio Marchionne said the company's U.S. unit Chrysler Group LLC aimed to sell over 800,000 Jeeps worldwide in 2013, setting a new high mark for the sports utility brand.
"Jeep's international development is one of the strengths of the group now," he told journalists at the Geneva car show.
"Last year we sold more than 700,000 Jeeps and this year we're aiming to sell more than 800,000. With the new Cherokee coming out in May we'll be in the largest (vehicle) segment in the U.S., and that's important."
Jeep's 2012 sales of 701,626, up 19 percent, topped the previous global high sales mark of 675,494 set in 1999.
Among Chrysler's four main brands, Jeep is the one that has the most global reach.
Sales in Asia rose 94 percent in 2012, they were up 29 percent in Europe and gained 18 percent in Latin America. Jeep's sales were up 13 percent in the United States at 474,131.
In the United States, Chrysler's top-selling brand last year was Dodge, which sold 825,917 vehicles, up 16.5 percent.
© Thomson Reuters 2017 All rights reserved.


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The Luxembourg Parliament adopted two new laws on 18 July 2016 (the "New Laws"), which update key features of some of Luxembourg's long-established and most frequently used corporate structures and introduce new structures....more
7/21/2016 - Board of Directors Capitalization Corporate Structures Joint Stock Companies Limited Liability Company (LLC) Luxembourg New Legislation Privately Held Corporations Shareholders
The entry into force of AIFMD in Europe has resulted in a double layer of regulation, as we now have regulation and supervision at the level of the product (regulated investment funds) and supervision at the level of the...more
7/15/2016 - AIF AIFM AIFMD Asset Management CSSF EU Institutional Investors Investment Companies Investment Funds Luxembourg Professional Investors Reserved Alternative Investment Funds (RAIF) SICAV
The Luxembourg financial regulator, the Commission de Surveillance du Secteur Financier (CSSF) published on 9 June 2016 an updated version of its FAQ concerning the Luxembourg law of 12 July 2013 on alternative investment...more
7/8/2016 - AIFM Alternative Investment Funds CSSF European Securities and Markets Authority (ESMA) Financial Services Industry Loan Origination Funds Luxembourg
Publication of corporate documentation in accordance with Luxembourg law will become fully digitalized. Luxembourg corporate entities – including investment funds – will benefit as instant publication results in savings of...more
5/18/2016 - Asset Management EU Investment Funds Luxembourg
Following hot on the heels of the introduction of the bill to implement the reserved alternative investment fund (RAIF), on 18 January 2016, the Luxembourg government deposited with Parliament a bill of law (Bill) to amend,...more
2/1/2016 - AIFMD Collective Investment Schemes Investment Funds Investors Luxembourg MiFID II Reserved Alternative Investment Funds (RAIF)
The Luxembourg Stock Exchange (the LuxSE) has implemented changes to its Rules and Regulations (the Rules) to adapt them to new practices and requirements of the market and its operators, as well as to bring the Rules into...more
1/27/2016 - EU Transparency Directive Financial Markets Luxembourg New Regulations
The Luxembourg supervisory authority, the Commission de Surveillance du Secteur Financier (CSSF), has recently issued FAQs regarding the immobilisation of bearer shares and units, as well as a press release to remind...more
4/6/2015 - AIFM AIFMD AIFS Bearer Shares CSSF Investment Funds Limited Partnerships Luxembourg Tax-Residency Certificate
One of the key drivers for the AIFMD1 is to monitor systemic risk by, among other means, collecting relevant information through harmonized reporting by alternative investment fund managers ("AIFMs") on their alternative...more
1/26/2015 - AIFM AIFMD ESRB EU European Securities and Markets Authority (ESMA) Harmonization Rules Luxembourg
The Luxembourg tax authorities have confirmed, by means of the long-expected Circular Letter L.I.R. nº 14/4 (the "Circular"), the treatment of tax transparent Luxembourg limited partnerships in the form of a société en...more
1/13/2015 - Corporate Taxes Limited Partnerships Luxembourg
Developments in the Luxembourg Financial Sector - The Luxembourg financial regulator, the Commission de Surveillance du Secteur Financier, has published two circulars pertaining to UCITS. The first is aimed at...more
10/21/2014 - EU Financial Regulatory Reform Foreign Banks UCITS
At the time of the transposition of the AIFMD into Luxembourg law, the Luxembourg government took the opportunity to reform the limited partnership regime, from both a corporate and fiscal perspective. The reform aims to make...more
10/31/2013 - AIFM AIFMD EU Fund Managers Limited Partnerships Recordkeeping Requirements
The Commission de surveillance du secteur financier (the "CSSF"), the Luxembourg supervisory authority, issued a circular on the authorization and organization of Luxembourg UCITS management companies and self-managed SICAVs....more
3/29/2013 - Financial Institutions Money Laundering Terrorism Funding
Investment Funds
Limited Partnerships
Asset Management
European Securities and Markets Authority (ESMA)
Reserved Alternative Investment Funds (RAIF)
Alternative Investment Funds
Bearer Shares
Board of Directors
Collective Investment Schemes
Corporate Structures
Corporate Taxes
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The MArch + MBA dual degree prepares students for the growing complexity of architectural practice and demand for managerial and administrative skills that often exceed the traditional training of the architect.
The establishment or management of a successful architectural office requires a wide range of skills. In addition to competence in traditional architectural roles, the growing complexity of the field demands a wide range of managerial and administrative skills. For instance, many architectural practices have expanded their range of services to include construction supervision, real estate development, multinational project management and public-sector consultation. The MArch/ MBA dual degree is intended to provide students with the skills and knowledge necessary to assume responsibilities for these challenges.
Interested students must apply to and be accepted by both the Department of Architecture and the School of Management. Enrolled students should consult the curriculum they were given upon entering the program, copies of which are kept in their student files in the departmental office.
We look forward to having you visit our School!
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Graduate students engage in research as a fundamental part of their curriculum through participation in our four Graduate Research Groups.


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Permanent-magnet stepping motors are generally thought of as low-torque devices. But, thanks to Micro Mo Electronics Inc., Clearwater, Fla., that's all changed with its introduction of a powerful new mini stepper measuring just 8 mm in diameter.
Traditional stepping motor technology was developed primarily for low-torque, limited-life applications such as disk drives, paper feeds, and primitive indexing functions.
Because the new AM0820 ministepper uses powerful neodymium magnets and provides holding torques of up to 0.106 oz-in., it can be used in smaller, more demanding applications such as miniature positioning stages, analytical instruments, test and measurement equipment, micropumps, laboratory robotics, and medical electronics.
Additionally, the new mini stepper along with its larger counterparts, is compatible with 8 and 10-mm diameter gearheads with ratios ranging from 4:1 to 4,096:1.


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Nighthawks Down Orabs in Softball Tournament Opener
Date posted - July 9, 2013
Boyden Hull Rock Valley topped Sheldon 6-0 in the opening round of the 3A Region 1 tournament. With the win the Nighthawks move on to the Friday semi finals against Sioux Center who turned back Spirit Lake 5-2 in the other lower bracket quarterfinal.
The Nighthawks plated 3 runs in the first inning as Nicole Ewoldt, Kensy Vande Hoef and Monserrat Figueroa Came in to score.
The Nighthawks scored three more in the bottom of the second as Sam Blum reached on a bunt single and later scored from third. Figueroa drove in the other two with a line drive homer to straight away center field. Vande Hoef who had reached on a bunt also came in to score as Boyden Hull Rock Valley took a 6-0 lead.
After that it become a pitchers dual with both teams playing strong defense. Joanna Heemstra earned the win going the first six innings. She gave up 3 hits walked 1 and struck out 6. CJ Vander Zwaag pitched a perfect seventh striking out two.
Allie Jongewaard took the loss giving up 3 hits. She walked 3, struck out one and did not give up a hit or run after the second inning.
With the win Boyden Hull Rock Valley improves to 21-3 on the year and will defend the home field again on Friday when they host Sioux Center in the lower bracket semi final.
In the upper bracket Garner Hayfield Ventura defeated Forest City 6-1 and will meet Estherville Lincoln Central a 13-0 winner over Algona in the upper bracket semi final Friday night in Estherville.
Sheldon ends the season at 13-14.
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Town Square
Today: Supes may vote on sales tax measure
Original post made on Jul 20, 2012
Read the full story here Web Link posted Friday, July 20, 2012, 11:01 AM
a resident of Menlo Park: Park Forest
on Jul 20, 2012 at 12:54 pm
I no longer have any confidence in how our elected officials spend our tax dollars.
Sales taxes are regressive and hurt lower income people far more than upper income people.
The Governor is eager to level additional sales taxes on us. Now, our County Supervisors wish to do the same.
With all due respect, Ms. Tissier, a Caltrain/HSR official and advocate, is not to be trusted with our tax dollars. Sorry.
No additional sales taxes, period.
a resident of Menlo Park: Sharon Heights
on Jul 20, 2012 at 1:41 pm
Old saying: "There is no such thing as a temporary tax."
a resident of Menlo Park: Downtown
on Jul 20, 2012 at 3:06 pm
What part of no didn't you understand in June. No increase in taxes. Seaton Medical Center, I don't think so.
a resident of Menlo Park: Downtown
on Jul 20, 2012 at 4:10 pm
"Insanity: Doing the same thing over and over again and expecting different results."
Albert Einstein
We obvious have really intelligent elected officials -- MP city council wants to raise the hotel tax when the county voted it down in June; the Board of Supervisors want to raise the sales tax to add to the general fund when the county voted down tax increases in June; and the legislature and governor want to raise taxes to fund HSR when other viable programs are cut and the state is going broke.
In a word -- NO!
a resident of another community
on Jul 20, 2012 at 6:23 pm
These are the supervisors who recently gave the Sheriff's Officers a 3% raise when others were asked to take a pay cut. When asked how will SMC be able to pay for this Don Horsley said " I don't know, we will have to worry about that when the time comes. This same group has just approved a Jail that they don't know or care about how are we going to afford to pay for it. They also just approve a raise for an employee who was just hired. They are not very good with the Taxpayers money.
NO on new taxes
a resident of Menlo Park: Downtown
on Jul 23, 2012 at 7:16 am
It's not just our area; the Sacramento area has the same issues Web Link.
Seems now-a-days every level of government wants more and more of your money. What kind of government system is that called again? I think there are a few countries in Europe like that.
a resident of Atherton: Lindenwood
on Jul 23, 2012 at 7:37 am
Peter Carpenter is a registered user.
" the San Mateo County Board of Supervisors finds itself confronting the same budget deficit with fewer options."
There is only ONE option - cut expenditures!!


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It seems like a new Ryan Adams clip has appeared online every day following the release of Ashes & Fire earlier this month. Today's video comes from England, where Adams appeared on Later with Jools Holland yesterday, performing the first single from that new record, "Lucky Now." Much has been written about Adams returning to Heartbreaker territory with this album, and it's not hard to see why when you listen to this well-constructed acoustic rendition of "Lucky Now." But anyone who thinks Adams isn't going to fire off at an unexpected tangent at any minute is sorely mistaken—just check out his fake video countdown show below.
Lil B - "Last Of The BasedWorld" (Video) | Thurz "Niggas" (Video) |


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Is this attraction a "must-see" location?
Is this location a solemn or serious place like a memorial, cemetary, etc.?
Is this attraction suitable for adults only?
Is this attraction good for couples?
Is this attraction suitable for all ages?
Would this be a good sunny day activity?
Is this attraction popular with tourists?
Is this attraction good for small groups (less than four)?
Would this be a good hot day activity?
Would this be a good cold day activity?
Thanks for helping!
O. Winston Link had a love affair with steam engines and a talent for showing them. He would take the photos at night and highlight what he wanted you to see with flashbulbs. He... read more
O. Winston Link had a love affair with steam engines and a talent for showing them. He would take the photos at night and highlight what he wanted you to see with flashbulbs. He showed the interaction of the public with its main method of travel in the first half of the twentieth century. Mostly black and white still shots,... More
This museum features pictures taken in the late 50's of steam locomotives and western Virginia during that time period. My wife is an artist and as such, she appreciated the staging and look of the pictures. This is an interesting hour or so if you have an interest in trains and the area.
Link was an incredible photographer of a time that contained locomotives, activities and change of the mid past century. He is the person that set the locomotives at the Virginia Transportation museum into the minds of many people worldwide, and has caused the community to save them as well. There are many rooms with incredible pictures. One could spend hours... More
We've seen a lot of Link's photographs - it was nice to put them in context. For those interested in the technology and craftsmanship of mid-century photography, this will be of particular interest. Appreciated the convenient seating for those who are less than mobile. Don't miss the separate (and free) exhibit on the work of industrial designer Raymond Loewy, located... More
Well known to rail fans, this unique museum is housed in an equally historic example of mid-century public architecture. The photographs of O. Winston Link are interesting AND artistic; the film about his life and work are icing on the cake.
Took my kids 8 and 12 to the art museum they loved the kid area and I loved the selection of art that was displayed I recommend going it is smaller than most big cities but well designed
His life, his start, his career, the multitude of photos and the different types of exposures he used and the PEOPLE that he captured in their work and life scenes with the different trains. just absolutely incredible museum. A must-see! It's only 12$ for a combined ticket with the Virginia Transportation Museum
Situated in the renovated passenger rail station across the street from The Roanoke Hotel, this museum presents black and white as well as color photos of steam trains in soutwest Virginia, West Vrginia and Kentucky. This shows the trains, locomotives, employees and towns they passed through in the LAte 1940's and early 1950's. O.Winston Link was a brooklyn born professional... More
If you like photography, you have to see this museum. O. Winston Link was taken with steam trains and the people who made them run. His photos tell such stories of a fairly recent past but the museum tells you HOW he got these shots, and even has hands on interactive ways to explain it. I was taken with it.
An absolute must for anyone who has ever had an interest in trains. This gem of a museum is great for the kiddies as well as adults. Well worth the price of admission.
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Currently Browsing
Posts Tagged ' Congress '
St. Paul studies sequester, says "Ugh!"
- 28 February //
- Posted in City Hall Scoop //
- Tags : Congress, HOME funds, R.T. Rybak, sequester, St. Paul Mayor Chris Coleman
- Comments Off on St. Paul studies sequester, says "Ugh!"
Minneapolis Mayor R.T. Rybak was recently quoted in the Washington Post saying that automatic budget cuts — referred to these days as "the sequester" — would impact services for the poor, hurting the have-nots in his city more than the middle class. Nevertheless, even large Minnesota corporations such as Best Buy and Target could feel the indirect impact if consumers spend less money during a time of uncertainty, he said.
Otherwise, Rybak and Hennepin County Commissioner Mike Opat, chair of the county board, sound almost calm about it all, at least in the Washington Post. The article is available online at http://www.washingtonpost.com/politics/impact-of-budget-cuts-depends-on-where-you-live/2013/02/26/f117a3c4-802f-11e2-b99e-6baf4ebe42df_story_1.html.
St. Paul on Thursday, Feb. 28 issued its own news release, and the tone is much more dire. An analysis by the city of St. Paul's Office of Financial Services predicts the effects of sequestration could impact everything from the city's investment and debt portfolio to public safety programs.
The city's 17 neighborhood district councils could lose a sizable chunk of city funding, though not right away, and housing development and emergency shelter grants would also be impacted through reductions of about 8.5 percent.
The city's full news release is below:
February 28, 2013
Effects of sequestration on the City of Saint Paul could be drasticSAINT PAUL — Today, an analysis by the City of Saint Paul's Office of Financial Services shows that the effects of sequestration on the City of Saint Paul could include potential cuts in public safety, a reduction in neighborhood programs, and could negatively impact the city's investment and debt portfolio.
"Only Congress has the power to pass legislation that prevents these severe cuts to public safety, economic development and the city's investment and debt portfolio," said Saint Paul Mayor Chris Coleman. "Communities across the country are just emerging from the worst recession in the history of the United States and are looking to Congress for a smart, thoughtful solution that doesn't penalize local communities. Sequestration could have dire effects on communities across the country and I urge Congress to find a better way forward."
Potential cuts to Saint Paul may include:
Approximately $1.5 million in funding for public safety, including:
· $250,000 to prevent human trafficking
· Up to $500,000 per year for equipment for Saint Paul firefighters
· More than $500,000 to help fund our Emergency Management and Police Department Information CentersAn 8.5 percent reduction in CDBG funds, HOME funds, and Emergency Shelter Grants that would:
· Limit the city's ability to fund district councils
· Hinder economic development programs when they are needed most
· Prevent further investment into Saint Paul's neighborhoods and communitiesThe City of Saint Paul is both an issuer and an investor in Build America Bonds. Sequestration could impact the cost of Saint Paul's payments to its investors while potentially preventing Saint Paul from selling these bonds in the future.
With permanent sequestration, the city estimates that impacts to the investment and debt portfolio could potentially add up to hundreds of thousands of dollars cut from the city's general fund over time.
Impacts on citizens from cuts to programs at the state and county level could also be devastating. $85 billion of sequester cuts are scheduled to take effect beginning March 1.
So what do you think about the sequester, dear Scoop reader? Should Congress allow these cuts to run their course? Is the president right in demanding fast action to avoid these budget cuts? And how much cause for alarm is there, really? Feel free to sound off, below….


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RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) today announced financial results for the fourth quarter and full year ended December 31, 2012.
"Our team is focused on achieving near-term milestones to rebuild shareholder value. Our primary goal is to advance our potentially ground-breaking oral kallikrein inhibitors for hereditary angioedema. Phase 1 clinical trials for the lead compound, BCX4161, are scheduled to begin in the next few months and we are finalizing lead optimization for our second generation compound," said Jon P. Stonehouse, President & Chief Executive Officer. "Furthermore, we are advancing BCX4430, a broad spectrum antiviral that could fill an important gap in the U.S. Government's medical countermeasure stockpile. Based on BCX4430's efficacy in treating various hemorrhagic fever viruses in animals, this compound could satisfy this important unmet need."
Fourth Quarter Financial Results
For the three months ended December 31, 2012, revenues decreased to $4.1 million, from $5.2 million in the fourth quarter of 2011. This decrease resulted primarily from a reduction in collaboration revenue from a contract with the Biomedical Advanced Research and Development Authority, within the U.S. Department of Health and Human Services (BARDA/HHS), for the development of peramivir.
Research and development (R&D) expenses for the fourth quarter of 2012 decreased to $11.1 million from $14.2 million in the fourth quarter of 2011. In 2012, lower development costs associated with the peramivir and ulodesine programs were partially offset by higher development costs associated with the preclinical BCX5191 and BCX4161 programs.
General and administrative (G&A) expenses for the fourth quarter of 2012 decreased to $1.9 million compared to $2.1 million in the fourth quarter of 2011, largely due to reductions in administrative expenses during 2012 associated with the continued realization of cost containment measures and the Company's restructuring of its operations. Fourth quarter 2012 expenses included a $1.8 million charge related to the corporate restructuring announced in December 2012.
Interest expense related to non-recourse notes was $1.2 million in the fourth quarter of 2012 and 2011. In addition, a $0.8 million mark-to-market gain on the Company's foreign currency hedge was recognized in the fourth quarter of 2012, compared to a $1.1 million mark-to-market loss in the fourth quarter of 2011. These hedge gains and losses resulted from changes in the U.S. dollar/Japanese yen exchange rate related to a foreign currency hedge arrangement entered into in conjunction with the RAPIACTA® royalty monetization transaction.
The net loss for the fourth quarter 2012 was $11.1 million, or $0.22 per share, compared to a net loss of $13.2 million, or $0.29 per share, for the fourth quarter 2011.
2012 Financial Results
For the year ended December 31, 2012, total revenues increased to $26.3 million from $19.6 million in 2011. The increase was due to the recognition of $7.8 million of previously deferred forodesine-related revenue in the first quarter 2012, as well as the recognition of $3.3 million royalty revenue from Shionogi & Co., Ltd. related to RAPIACTA® sales in the second half of 2012. The aggregate revenue increase was partially offset by a decrease in peramivir collaboration revenue from BARDA/HHS due to a reduction of peramivir development activity in 2012, as compared to 2011.
R&D expenses decreased to $51.5 million for 2012 from $57.2 million in 2011. A decrease in 2012 development costs related to the ulodesine and peramivir programs were partially offset by higher BCX5191 and BCX4161 development costs, as compared to 2011. Expenses for 2012 included the recognition of $1.9 million of non-cash, previously deferred expenses associated with the transfer of forodesine development activity to Mundipharma International Holdings Ltd. in the first quarter of 2012.
G&A expenses decreased significantly to $6.8 million in 2012 from $12.0 million in 2011, due to realization of cost containment measures, and the relocation of BioCryst's corporate headquarters in 2011. Total operating expenses decreased to $60.2 million in 2012 from $69.2 million in 2011.
The net loss for 2012 decreased to $39.1 million, or $0.79 per share, compared to a net loss of $56.9 million, or $1.26 per share for 2011.
Cash and investments totaled $37.1 million at December 31, 2012, a $20.6 million decrease from the $57.7 million balance at December 31, 2011. Net operating cash use for the fourth quarter of 2012 was $7.1 million and excludes $0.3 million of collateral received under the Company's foreign currency hedge arrangement. Net operating cash use for 2012 was $36.8 million, which was at the low end of BioCryst's net operating cash use guidance of $37 to $43 million, and total cash use was $38.5 million.
Clinical Development Update & Outlook
- In December, BioCryst restructured its operations and implemented a focused R&D strategy to advance its hereditary angioedema (HAE) and antiviral programs. The restructuring and R&D focus significantly reduced BioCryst's future cost structure. The Company expects to reduce its operating cash burn by 30% to 40% and its operating expenses by 40% to 60% in 2013, as compared to 2012. These reductions enable the Company to extend its cash runway to achieve important near-term milestones in its oral HAE and broad spectrum antiviral programs.
- In January, the Company announced the termination of its antiviral development program for treatment of the hepatitis C virus (HCV). Following seven days of treating HCV-infected animals with BCX5191, the viral load reduction observed was insufficient to justify continued development.
- BioCryst plans to initiate its BCX4161 Phase 1 program for HAE around the end of the first quarter 2013. The main success factors for the BCX4161 Phase 1 clinical trial are to demonstrate safety, adequate and consistent drug exposure, and pharmacodynamic effects after oral administration. In addition, BioCryst has identified several second generation oral HAE compounds, and plans to select a lead candidate later in 2013.
- Proof-of-principle data demonstrating that BCX4430 was efficacious and well tolerated in a preclinical yellow fever virus infection disease model was presented at the 2nd Antivirals Congress in Cambridge in November. BioCryst is continuing its collaboration with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) regarding filoviruses, while seeking additional U.S. Government funding for the further development of BCX4430. BioCryst expects to provide additional BCX4430 updates throughout 2013.
- In November, the independent data monitoring committee (DMC) overseeing the peramivir Phase 3 clinical trial in hospitalized influenza patients informed the Company that the recalculated sample size for the clinical trial had crossed the pre-specified futility boundary of 320 subjects. Following this notification, BioCryst terminated the clinical trial, completed its analysis of the Phase 3 results and shared the data and findings with BARDA/HHS. In the coming months, the Company plans to have additional discussions with BARDA/HHS and the Food and Drug Administration to determine the future of the U.S. peramivir program.
Financial Outlook for 2013
Based upon current trends and assumptions, as well as the Company's restructured operations, BioCryst expects 2013 net operating cash use to be in the range of $22 to $26 million, and its 2013 operating expenses to be in the range of $25 to $35 million.
Conference Call and Webcast
BioCryst's leadership team will now host a conference call and webcast today, February 19, 2013 at 11:00 a.m. Eastern Time to discuss these financial results and recent corporate developments. To participate in the conference call, please dial 1-877-303-8027 (United States) or 1-760-536-5165 (International). No passcode is needed for the call. The webcast can be accessed by logging onto www.BioCryst.com. Please connect to the website at least 15 minutes prior to the start of the conference call to ensure adequate time for any software download that may be necessary.
About BioCryst Pharmaceuticals
BioCryst Pharmaceuticals designs, optimizes and develops novel small molecule drugs that block key enzymes involved in infectious and inflammatory diseases, with the goal of addressing unmet medical needs of patients and physicians. BioCryst currently has two late-stage development programs: peramivir, a viral neuraminidase inhibitor for the treatment of influenza, and ulodesine, a purine nucleoside phosphorylase (PNP) inhibitor for the treatment of gout. In addition, BioCryst has several early-stage programs: BCX4161 and a next generation oral inhibitor of plasma kallikrein for hereditary angioedema and BCX4430, a broad spectrum antiviral for hemorrhagic fevers. For more information, please visit the Company's website at www.BioCryst.com.
Forward-Looking Statements
This press release contains forward-looking statements, including statements regarding future results, performance or achievements. These statements involve known and unknown risks, uncertainties and other factors which may cause BioCryst's actual results, performance or achievements to be materially different from any future results, performances or achievements expressed or implied by the forward-looking statements. These statements reflect our current views with respect to future events and are based on assumptions and subject to risks and uncertainties. Given these uncertainties, you should not place undue reliance on these forward-looking statements. Some of the factors that could affect the forward-looking statements contained herein include: that BioCryst or its licensees may not be able to enroll the required number of subjects in planned clinical trials of its product candidates and that such clinical trials, including the planned Phase 1 clinical trial for BCX4161, may not be successfully completed; that the Company or its licensees may not commence as expected additional human clinical trials with product candidates; that the FDA may require additional studies beyond the studies planned for product candidates or may not provide regulatory clearances which may result in delay of planned clinical trials, may impose a clinical hold with respect to such product candidate, or withhold market approval for product candidates; that BioCryst may not receive government funding to support the further development of BCX4430; that BARDA/HHS may further condition, reduce or eliminate future funding of the peramivir program; that peramivir may never be approved for any use by the FDA; that ongoing and future preclinical and clinical development may not have positive results; that the Company or its licensees may not be able to continue future development of current and future development programs; that such development programs may never result in future product, license or royalty payments being received; that the Company may not be able to retain its current pharmaceutical and biotechnology partners for further development of its product candidates or may not reach favorable agreements with potential pharmaceutical and biotechnology partners for further development of product candidates, including ulodesine; that its actual financial results may not be consistent with its expectations including that 2013 operating expenses and cash usage may not be within management's expected ranges. Please refer to the documents BioCryst files periodically with the Securities and Exchange Commission, specifically BioCryst's most recent Annual Report on Form 10-K, Quarterly Reports on Form 10-Q, and current reports on Form 8-K, all of which identify important factors that could cause the actual results to differ materially from those contained in BioCryst's projections and forward-looking statements.
(in thousands, except per share amounts) | |||||||||||||||||
Statements of Operations | |||||||||||||||||
Three Months Ended | Twelve Months Ended | ||||||||||||||||
December 31, | December 31, | ||||||||||||||||
2012 | 2011 | 2012 | 2011 | ||||||||||||||
Revenues: | |||||||||||||||||
Royalty revenue | $ | 469 | $- | $ | 3,317 | $ | - | ||||||||||
Collaborative and other research and development | 3,632 | 5,224 | 22,976 | 19,643 | |||||||||||||
Total revenues | 4,101 | 5,224 | 26,293 | 19,643 | |||||||||||||
Expenses: | |||||||||||||||||
Research and development | 11,090 | 14,198 | 51,464 | 57,249 | |||||||||||||
General and administrative | 1,929 | 2,068 | 6,826 | 11,981 | |||||||||||||
Royalty expense | 18 | - | 132 | - | |||||||||||||
Restructuring costs | 1,759 | - | 1,759 | - | |||||||||||||
Total expenses | 14,796 | 16,266 | 60,181 | 69,230 | |||||||||||||
Loss from operations | (10,695 | ) | (11,042 | ) | (33,888 | ) | (49,587 | ) | |||||||||
Interest and other income | 40 | 84 | 222 | 413 | |||||||||||||
Interest expense | (1,180 | ) | (1,160 | ) | (4,666 | ) | (3,774 | ) | |||||||||
Loss on foreign currency derivative | 782 | (1,074 | ) | (749 | ) | (4,000 | ) | ||||||||||
Net loss | $ | (11,053 | ) | $(13,192 | ) | $ | (39,081 | ) | $ | (56,948 | ) | ||||||
Basic and diluted net loss per common share | $ | (0.22 | ) | $(0.29 | ) | $ | (0.79 | ) | $ | (1.26 | ) | ||||||
Weighted average shares outstanding | 50,883 | 45,266 | 49,474 | 45,144 | |||||||||||||
Balance Sheet Data | |||||||||||||||||
December 31, 2012 |
December 31, 2011 | ||||||||||||||||
Cash, cash equivalents and securities | $ | 36,750 | $ | 57,100 | |||||||||||||
Restricted cash | 308 | 625 | |||||||||||||||
Receivables from collaborations | 4,562 | 5,831 | |||||||||||||||
Total assets | 57,439 | 82,208 | |||||||||||||||
Non-recourse notes payable | 30,000 | 30,000 | |||||||||||||||
Accumulated deficit | (392,601) | (353,520) | |||||||||||||||
Stockholders' (deficit) equity | (454) | 14,806 |


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Gustavo A. Madero (gōstäˈvō ä mädāˈrō) [key], city (1990 pop. 1,268,068), Federal District, S central Mexico. Formerly called Guadalupe Hidalgo, it was renamed in 1931. It is the site of the Our Lady of Guadalupe shrine and is a major Roman Catholic pilgrimage center. The treaty of Guadalupe Hidalgo (1848), which ended the Mexican War, was signed there.
The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2012, Columbia University Press. All rights reserved.


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Lil Jon Twitterview
By Dana Flax
Known as the ambassador to all things crunk (crunk music, Crunk!!! Energy Drink and, you know, the "pimp cup"), Lil Jon possesses no shortage of enthusiasm. That's why we asked him if he'd join us for a high-energy Twitterview, where we could get the lowdown on his new album "Crunk Rock," his personal grills-hygiene habits and his epicurean tastes.
Check out our exclusive Twitterview with LJ (Be warned: There's plenty of caps lock), then follow @WonderwallMSN and @LILJIZZEL to ensure plenty of celeb news bites and YEAHs populate your Twitter timeline.


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Photos courtesy Maggie Ives
Big Brothers Big Sisters celebrated at their summer picnic with model rockets. There were nine children participating and thanks to Quest, the county airport and the San Juan Outdoor Club, the kids were able to build and launch two types of rockets — water rockets and motor-powered rockets. The kids were more interested in the rockets than they were in hamburgers, so everyone quickly proceeded to the main activity of the day — several launches, with the help of Jim Lesch and Joe LaMastra.
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Telemedicine Versus Traditional Treatment of Muscle Tension Dysphonia
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this research is to determine whether treatment of voice disorders can be provided just as effectively using telemedicine as it can using on-site, traditional therapy. An exercise protocol for improving airflow with voicing has been demonstrated to be effective in a prior UAMS investigation (Protocol 107454). These exercises are used as part of the normal clinic routine at UAMS working with individuals with voice problems. The three exercises used are: gargling with and without voicing; cup bubble blowing with and without voicing; and, stretch and flow exercises, which involves the use of a piece of tissue to provide visual biofeedback on the ability to use proper airflow with voicing. The purpose of the exercises is to increase airflow and breathiness in the voice and reduce muscle tension. In addition, patients will be taught to use a "confidential voice" or gentle voice during speaking.
The investigators voice patients come from all over the state and many cannot return for regular treatment. Developing a way to provide treatment to them closer to home could greatly improve quality of care and quality of life. Twenty participants will participate for 12 sessions each. All participants will be evaluated at UAMS before and after treatment as part of standard care and will, upon consent, be randomized to receive treatment via telemedicine at an AHEC site or at UAMS Medical Center. Homework will be provided along with log sheets. Results of airflow measures using an airflow-recording device (Viasys, KAY/PENTAX) pre- and post treatment will determine whether telemedicine results are equal to results of traditional, on-site treatment. The investigators hypothesize that results from treatment using telemedicine will be equivalent to results for onsite, traditional treatment.
Condition | Intervention | Phase |
Muscle Tension Dysphonia |
Behavioral: Airflow Exercises for Voicing |
Phase 1 Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single Blind (Investigator) Primary Purpose: Treatment |
Official Title: | Telemedicine Versus Traditional Treatment of Muscle Tension Dysphonia |
- Mean Expiratory Airflow During Comfortable Phonation [ Time Frame: 6 weeks ]Measured pre- and post in liters/second using Phonatory Aerodynamic System.
- Voicing Efficiency [ Time Frame: 6 weeks ]Mean Airflow during voicing efficiency task, pa-pa-pa, using Phonatory Aerodynamic System. Measured in liters/second.
- Voice Handicap Index Questionnaire [ Time Frame: 6 weeks ]Patient's perceived ratings of Voice Handicap on standardized, validated questionnaire.
- Consensus Auditory Perceptual Evaluation of Voice [ Time Frame: 6 weeks ]Overall perceptual rating of voice quality made by clinician on 100 point scale.
Enrollment: | 14 |
Study Start Date: | August 2011 |
Study Completion Date: | August 2013 |
Primary Completion Date: | August 2013 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Active Comparator: Traditional, Onsite Treatment
Onsite treatment using airflow exercises. Patients will receive face-to-face treatment with the research speech pathologist two times per week.
Behavioral: Airflow Exercises for Voicing
Gargling, Cup Bubble Blowing, and Stretch and Flow Exercises will be taught to reduce laryngeal closure and improve airflow through the glottis during voicing.
Experimental: Telemedicine Treatment
Participants will receive treatment via telemedicine at select AHEC sites around the state of Arkansas. Treatments will occur twice per week with the research speech pathologist.
Behavioral: Airflow Exercises for Voicing
Gargling, Cup Bubble Blowing, and Stretch and Flow Exercises will be taught to reduce laryngeal closure and improve airflow through the glottis during voicing.
Ages Eligible for Study: | 21 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Primary or Secondary Muscle Tension Dysphonia
Exclusion Criteria:
- Head and Neck Cancer
- Spasmodic Dysphonia
- Tremor
- Respiratory Compromise
- Dysphagia
Please refer to this study by its ClinicalTrials.gov identifier: NCT01419444
United States, Arkansas | |
UAMS Medical Center Voice and Swallowing Clinic | |
Little Rock, Arkansas, United States, 72205 |
Responsible Party: | University of Arkansas |
ClinicalTrials.gov Identifier: | NCT01419444 History of Changes |
Other Study ID Numbers: |
Study First Received: | August 16, 2011 |
Last Updated: | December 17, 2013 |
Keywords provided by University of Arkansas:
Voice Muscle Tension Dysphonia Hyperfunction Treatment |
Additional relevant MeSH terms:
Dysphonia Hoarseness Voice Disorders Laryngeal Diseases Respiratory Tract Diseases Otorhinolaryngologic Diseases |
Neurologic Manifestations Nervous System Diseases Signs and Symptoms Respiration Disorders Signs and Symptoms, Respiratory |
ClinicalTrials.gov processed this record on March 29, 2017


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I think it's safe to say the Rangers are going to win the AL West. They may not possess the same quality starting pitching like the Angels, but they have an offense that is 2nd to none.
Texas recently hammered a Cleveland team that has 2 feet in the sand. The Angels, on the other hand, got pounded by a Baltimore team playing for nothing, as usual.
Dan Haren, Jered Weaver and Ervin Santana have kept this weak Angel team in the race all year. By weak, I mean offensively. Those 3 pitchers have to be near perfect every time because the offense just doesn't have the bats to consistently produce day after day. I was nervous after the Orioles took a 2-0 lead in the 3rd inning on Friday. When they added 3 in the 5th, and 6th, I knew the game was over.
I guess if the Halos go on an 8 game winning streak, those last 3 at Anaheim Stadium against the Rangers will mean something. I wouldn't bet on that happening.
After the O's lit up Haren, they took to beating up Tyler Chatwood. Chatwood looks gassed. I wonder why Mike Scioscia won't go to Garrett Richards. Chatwood gave up a wild pitch, a home run, a walk and a single before finally getting out of the 6th inning.
I like the fact that Vernon Wells now shows emotion, but I wonder why he always gets mad when, after swinging at a high fastball, he strikes out. He always strikes out on high gas.
Angels get a few useless runs in the 9th, but still lose 8-3. The Rangers were blanked by Seattle, 4-0, so they remained 3.5 games ahead of the Angels.
Lately, every Halo starter has gotten in to the habit of,not just walking guys, but walking them at the all the wrong times.
The first run scored against Haren on Friday was put there via the BoB. Saturday, same story. Ervin Santana walked the first man he faced, JJ Hardy followed with a 2-run shot. I'll go out on a limb and say, right now, game over. Now, I'll guarantee it. Mark Reynolds just hit a 3-run shot. The O's sent only 10 men to the plate in the bottom of the 1st, and lead 5-0. The Angels do not have a consistent enough offense to come back, so the only hope is that the Rangers lose. They didn't, beating Seattle 7-6.
Richards pitched on Saturday, giving up one run in 1 inning of work. I guess that's why they don't go to him more.
Most any other time, I would be mad, but I am not. The 3 big guns for the Angels have carried this team all year. It's not fair to expect them to be perfect every start. Unfortunately, Pineiro can't pitch, Williams is untested, Chatwood isn't ready, and Richards, who knows. That doesn't even take in to account the Angels squeaky bullpen. If the Angels had a trusted pen, Santana might not have made it through the first.
I think it's a mistake, but Weaver is supposed to go tomorrow on 3 days rest. He doesn't have the body type of a CC Sabathia to do that on a consistant basis.
Angels now 4.5 back. They'll try to avoid being swept tomorrow.
Go Angels!
About the Author
Written by Bill Mahoney
O'kay I'll talk about myself a little. I've been working in the television/radio industry for over 21 years. I started at 2 so I am just a tad over 21 (That is a joke). My career has taken me around and and even out of the United States. Right now I call Vegas home, but I just never know where life will take me next. Until 2002 my irrational love for the California/Anaheim/LAA had taken me down some very dark roads, but with Arte Moreno in charge I finally saw the a light at the end of the road. I really love most every sports and having as much fun as possible.


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OWASP on the Move
From OWASP
Revision as of 14:38, 27 April 2011 by Alison.McNamee (talk | contribs) (→OWASP On the Move Rules:)
This program allows local chapters to have OWASP presenters on site.
It is NOT for speakers to attend OWASP conferences.
This program allows 3 parties to find each other:
- Local chapters events that want to attract an OWASP speaker
- OWASP speakers to entertain OWASP presentations and that want to see the world
- OWASP sponsors that want to support spreading the OWASP message
To find available speakers in your area, see the OWASP Speakers Project
Application Process
The way it works is really easy.
- Upfront the chapter leader sends the OotM request (event details, who to cover, etc...) to Kate
- If within the rules (see below) it will be rapidly approved by Kate
- The speaker, who made the travel/lodging expenses, e-mails a scan of the receipts to Kate after the presentation is performed
- Kate re-imburses up to the approved budget and informs the chapter leader
That's it!
OWASP On the Move Rules:
The following rules apply for the OotM project:
- Primary funding would be deducted from the local chapter budget.
- A chapter without sufficient funds for a speaker may request the Global Chapter Committee vote to approve the use of OWASP funds.
- The normal maximum amount per speaker is 500 USD
- Only in special circumstances the maximum amount per speaker can be raised to a maximum of $1000 USD
- There is a proposed limit of 2,000 USD on the amount of $ provided to any individual per year (*see 'further funding' below)
- There is a proposed limit of 2,000 USD on the amount of $ provided to any chapter per year(*see 'further funding' below)
A chapter can use the sponsorship 4 times a year, with a maximum of 2 speakers sponsored by OotM for one single event.
- Further funding: for active chapters or speakers who have reach the proposed financial limits, further funding is possible but will depend on available budget, since priority would be given to chapters below these thresholds
OWASP on the Move funds are not to be used by speakers to attend OWASP conferences. If assistance is needed to attend a conference, contact the conference chair.
The payments are tracked online OWASP_on_the_Move_-_Payments