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Indoor activities for a high drive dog
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post #1
Thread Starter
Join Date: Oct 2012
Location: Charlotte, NC
Posts: 83
Indoor activities for a high drive dog
I was looking for some advice on fun things to do with our dog indoors. She's a working line dog and when she doesn't have a "job" to do she gets a bit cranky. I feel like we've got a pretty good array of outdoor activities for her already. Outside she'll happily play fetch until she looks like she is going to drop dead, she loves to tug and she will also "such" for treats that we hide out in the yard. That along with 2-3 2 mile walks a day and hiking on the weekend seems to keep her pretty happy.
That said sometimes it's just too nasty to be outside for long (honestly she'd be perfectly happy throwing a ball in the middle of a tornado, it's us humans that don't want to be out there) and on those days where she doesn't have a good outlet she can be a bit of an annoyance. She will sit in front of us and paw at us and whine or frap around the furniture because she's bored. We don't really have room to play fetch in the house but we do hide treats around and have her scent them out and we play tug.
I've thought about pulling the cars out of the garage to give us some room to play but, I worry about the garage floor being too slick and her getting hurt. I tried the dog boots but they just roll over and don't work. We don't have a treadmill and don't have room for one. There aren't any good indoor play places near by either.
So as the oppressive heat and humidity of summer are closing in and there will likely be less time spent outside, do you guys have any ideas on other things we can do in the house to tire her out both physically and mentally?
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Dude, I opened it up at noon, and it is sweet!!
I'm diggin it. Its a small package, perfect for tossin in a cargo pocket. Just what I was hoping for. It might even make a nice neck knife.
Very nice grinds and shaving sharp. Thank you!
Dude, I opened it up at noon, and it is sweet!!
I'm diggin it. Its a small package, perfect for tossin in a cargo pocket. Just what I was hoping for. It might even make a nice neck knife.
Very nice grinds and shaving sharp. Thank you!
It takes more of a man to be a gentleman.
Ps 83:18; Is 43:12
Sorry. The awesomeness must have created a double post.
It takes more of a man to be a gentleman.
Ps 83:18; Is 43:12
LOL glad you liked it... it is a nice knife and I kinda like the thin handles just a tad bit thinner then what I'm used to putting out there.. sorry I just couldn't resist putting up a couple of my sorry photo skill shots...
It takes more of a man to be a gentleman.
Ps 83:18; Is 43:12
the fuzzy fuzzsters....
Great looking blade Rob! Love the "lined" sheath Nice touch Bro!
Hello Folks,
This is the Creekster's first time out, albeit brief. The knife was very comfortable and controllable in the hand. I used the knife to drill a hole and produce some shavings or feather sticks. We got along very well!
I hope you enjoy.
Obligatory Knife Photos.
Integrity Counts
WOW !!! you guys and your feather sticks are killing me, I'm going to have to brush up on my skills that's for sure...
Mark the pictures look great, love the etch on that knife simply beautiful (but I may be biased )... my pics never seem to do the knife justice but yours have.. You've really put it to use drilling that hole, incredible...
guys I stand in awe and am completely humbled to see pictures of these knives and taken back even more to see many of you guys taken a liking to them..
if there are any improvements you'd like to add or would like to see in the future please, let me know.. you're advice is greatly appreciated..!!!
Hi Rob,
Thank you for your kind words. Keep doing what you are doing!
I like the Creekster I received for a number of reasons.
The spine of the knife is square (has crisp 90-degree edges) which offers me great utility. I can use the spine of my knife in a scraping action to remove bark, create very fine shavings, or create sparks from my Light My Fire (LMF) firesteel. The only down side of the square spine is that it is a touch uncomfortable when doing push -cuts with my bare thumbs. But I feel the utility offered here outweighs the minor discomfort. Plus, I have leather thumb guards if becomes that unbearable.
The knife is of the right proportions which makes it great for carving and whittling and is stout enough for batoning. This allows me to process wood and prepare kindling very effectively.
Yep, I think I like this knife very much!
I guess if I had my druthers, I would like to see this knife also offered with a blade shape that is similar to Ray Mears/Alan Wood Woodlore knife. I have several of these knives and am partial to them.
Thank you kindly. Take care.
Integrity Counts
Mark hope your knife is still serving you well....
Here's a few pics of my MANchete Golok 13 that I've had sitting on my workbench since September in various states of completion, we'll I finally finished it and shipped it off to Balding Eagle.. I can't wait to see the sheath he makes for this badboy knowing him its going to be awesome !!
MANchete Golok 13
Man oh man. That thing looks awesome!!! I am so going to cherish this. I will certainly post pics of the sheath I make for that bad boy. Simply beautiful Rob. Thanks so much!! I can't wait to show this off at work. Regarding your move........I wish you all the best. Being in the Air Force for 27+ years, we have made many moves, around the world and back. But, at least, we always had someone move for us. Moving yourself is a whole different thing. Good luck. As hectic as it may seem, it all comes together in the end.
And again, thanks so much for this beautiful blade!
Doug I'm just glad I could finally get it out to you.... I'll PM you the tracking info, and I'm really excited to see what you have in store for it... !!!
Integrity Counts
lol... no problem I've been kinda slacking on bumping posts in this forum until I start slinging some sparks.... then maybe things will pick up a little around here....
that is curly maple in the pics..
Rob needs to get behind a grinder again!
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This little one is only 2 days old. She was home less than an hour from the hospital when I arrived. Poor mom had very little time to unwind before the session. She is a sweet, tiny little baby. The wrinkled feet really show how new this bundle was. I can't wait to edit the rest of this session. Here is a tiny sneak peek.
We tried to take off her little bandaids, but the spots were still bleeding… poor thing had little round bandaids on both heels and both arms.
2 days…
This girl JUST had a baby!? WOW! I hope I look that good!
what a beautiful mom and little girl – I love those wrinkly feet – they are gone so quickly!
My daughter and grand daughter…how beautiful. I can't wait to see all the pictures. Melissa did an extra ordinary job! Thank you for helping us catch this special day and family on camera!!!
Thank you so much for taking the pictures! They were absolutely gorgeous & i can't wait to see the rest of them. I'll def be getting up with you more in the future!
my neice and cousin! arent they gorgeous! you did great work 🙂
Oh wow, these are so amazing. How wonderful to have a fresh brand new baby to photograph! I commend the new mommy for having newborn pictures so soon!


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Monday, February 1, 2010
Please HELP! We Need You!
My friend Jodi of thisisit creations, just found out that three bulls who graze on her land are going to be slaughtered. So she asked the owner if he would sell them to her instead. He agreed. Now we are raising money. He needs to have the money in two weeks. So please donate, don't delay!!
I am donating 100% in my etsy shop.
Several others are also stepping up with a portion of proceeds and other donations.
Please check the Veganetsy blog & also Etsyveg's blog for updates as they come along. Jodi's blog is here. I will also update this blog if I see get any news.
If you would prefer send a check here:
This Is IT! Creations
P.O. Box 1252
Jacksonville, OR 97530
Thanks for your help! XOXO Heather :)
chip in,
rescue cows,
vegan etsy
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The Atlantic Inn
High St
(401) 466-5883
Water Street
(401) 466-2231
Located right on the beach!
Block Island Maritime Institute
Ocean Ave
email: firstname.lastname@example.com
Great place to have weddings, parties, meeting and special events. On the harbor in New Harbor.
The Inn at Block Island
Old Town Road
(401) 466-5524, (877) 324-4667
Ocean views, full breakfast, pet friendly, quiet location. A short walk to the beach, harbors and town.
National Hotel
High Street
(401) 466-2901
We can accommodate groups of 5 to 50 for business meetings, meals, overnight stays, rehearsal dinners and other special occasions.
Payne's Harbor View Inn
Beach Avenue
(401) 466-5758
We provide the perfect setting for your wedding and reception with unequaled beauty, romance & adventure. Overlooks the Great Salt Pond
Rebecca's Dockside
Ocean Ave (Payne's Dock)
(401) 741-3492
Upstairs deck in and outside seating overlooking Great Salt Pond. Wonderful sunsets!
Rose Farm Inn
High Street
(401) 466-2034
Spring Street
(401) 466-5396
The Sullivan House
Corn Neck Road
(401) 466-5672
Block Island's premier location for special events where elegance, natural beauty and fine cuisine set the stage for spectacular weddings, private parties and conferences. Accommodates small parties and large parties up to 350 guests.


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Buddha Lounge Soundtrack
Sigue Sigue Sputnik, The Tokens, Edith Piaf, Marvin Gaye, Ben E. King, Shannon, Santana, Percy Sledge, Skin Flesh & Bones, Bob Marley, The Buddha Lounge Players, Los Cuentos De Hoffman, Berlin, Lorena, Bypass Unit, Lucky Star Players, Night Shifters, Top Affair All Stars, Shiny Toy Guns, DJ Trick Z, Sarah Vaughan, Electro Trials, Barry's All Stars, The Revolutionaries, Tosca, Lakeme, Nocturnal Classical Players, L'elisir D'amore, Turnadot, Cry Tuff, We The People Band, Harry J. All Stars
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your special friend donald...
how's donald been lately
IF U WERE KILLED TOMORROW, I WOULDNT GO 2 UR FUNERAL CUZ ID B N JAIL 4 KILLIN DA MOTHA FUKER THAT KILLED U! ..._...|..____________________, , ....../ `---___________----_____|]= ...../_==o;;;;;;;;_______.:/ .....), ---.(_(__) / ....// (..) ), ----" ...//___// ..//___// .//___// WE TRUE HOMIES WE RIDE TOGETHER WE DIE TOGETHER send this GUN to every thread you care about including this one if you care. Count how many times you get this, if you get a 13 your A TRUE HOMIE
yo so I heard your a moderator so can you like approve of my 3 pictures thanks
If I got a euro for everytime I heard that, well, let's say I'd be able to buy a few sweets.
Hello Atty, I'm pulling a Heathen on you.
eh, idk. I was bored when I messaged you and now I guess I can get to know you or something.
Send an Instant Message to Atty Using...
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State your identity!
j͆ͪ͟c̓̊͜a̎ͨ̈́ͧṗ̵ ̏ͭ̃sͪ̊͊̒͌̒̏t͗͗ͩͮo̧̊̒̎̽̇̌̋ṗ̸ͪ͑ͩ̐
El Durado :/


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Saborna crkva
From Wikipedia, the free encyclopedia
(Redirected from Saborna Crkva)
Saborna crkva means 'Orthodox cathedral' in Serbian. It may refer to the following cathedrals:
- St. Michael's Cathedral (Belgrade)
- Saint George's Cathedral (Novi Sad)
- Holy Trinity Cathedral (Niš)
- Serb Orthodox Cathedral (Sarajevo)
This disambiguation page lists articles associated with the title Saborna crkva. If an internal link led you here, you may wish to change the link to point directly to the intended article. |


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On the behaviour of time discretisations of the electric field integral equation
Davies, Penny and Duncan, D.B. (2000) On the behaviour of time discretisations of the electric field integral equation. Applied Mathematics and Computation, 107. pp. 1-26. ISSN 0096-3003
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
We derive a separation of variables solution for time-domain electromagnetic scattering from a perfectly conducting in®nite ¯at plate. The time dependent part of the equations are then used as a model problem in order to study the e€ects of various time discretisations on the full scattering problem. We examine and explain how exponential and polynomial instabilities arise in the approximation schemes, and show that the time averaging which is often used in an attempt to stabilise solutions of the full problem acts to destabilise some of the schemes. Our results show that two of the time discretisations can produce good results when coupled with a space-exact approximation, and indicate that they will be useful when coupled with an accurate enough spatial approximation.
Item type: | Article |
ID code: | 34573 |
Keywords: | discretisations , electric field integral equation, Mathematics, Computational Mathematics, Applied Mathematics |
Subjects: | Science > Mathematics |
Department: | Faculty of Science > Mathematics and Statistics |
Depositing user: | Pure Administrator |
Date Deposited: | 10 Nov 2011 15:16 |
Last modified: | 22 Mar 2017 11:44 |
Related URLs: | |
URI: | http://strathprints.strath.ac.uk/id/eprint/34573 |
Export data: |


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I heard you have to send your pms here to get a code http://gamers.eurogamer.net/user_profile.php?user_id=49901 I will be if it gives me a better chance of getting beta. |
#3860500, By --Loco-- When are the COD WaW beta tokens coming??
--Loco-- 22 posts
Seen 7 years ago
Registered 10 years ago


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Glass Identification - Post here for all ID requests > Glass
Bowl by Iittala, Finland?
Anne E.B.:
Just this sec. spotted it, and another Humppila bowl which bears some similarities....
:lol: Beaten to it by Frank :P
This one looks more like mine.
Both are far more exciting than my restrained version. Mine doesn't have the same flamboyant uneven edge.
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news, mugshots.com, unconstitutional mugshot laws, exonerations, arrest records, FBI most wanted
mugshot, mugshots.com news, mugshot news, editorials, opinion, mugshots
Chris Aranda
Who is Chris Aranda? Was Chris Aranda arrested? When was Chris Aranda arrested? What was Chris Aranda arrested for? Is this a mugshot of Chris Aranda? Are there more Mugshots of Chris Aranda? Are Mugshot laws constitutional? Who decides which Mugshots are Indexed? Why must Mugshots remain public mugshots and public record? Is this the Chris Aranda you know?
Chris Aranda was booked in Santa Fe County, NM on 2/09/2009 at 22:02.
All are presumed innocent until proven guilty in a court of law. Published mugshots and/or arrest records are previously published public records of: an arrest, an indictment, a registration, the deprivation of liberty or a detention. The mugshots and/or arrest records published on Mugshots.com are in NO way an indication of guilt and they are NOT evidence that an actual crime has been committed. For latest case status, contact the official law enforcement agency which originally released the information.
The following Official Record of Chris Aranda is being redistributed by Mugshots.com and is protected by constitutional, publishing, and other legal rights. This Official Record was collected from a Law Enforcement agency on 9/30/2011.
Mugshots.com ID: 4139622
Last Name: ARANDA
First Name: CHRIS
Middle Name: N/A
Suffix: N/A
Address: 8 JORANDA WAY
City: SANTA FE
Zip: 87508
Birth date: 11/20/1987
Race: W
Gender: M
Height: 5′ 8″ (1.73 m)
Weight: 150 lb (68 kg)
Hair Color: BRO
Eye Color: HAZ
InmateID: 339747
Booking No: 0900011084
State No: 012090012946
Location: RELEASED
Booking Date: 2/09/2009 at 22:02
Release Date: 2/09/2009 at 23:02
External Links:
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Lot 3305: French chateau-form paint decorated dog house
Millea Bros "SELECT" (Day 3 of 3)
by Millea Bros. Ltd.
05 November 2016
Boonton, NJ, USA
Live AuctionSold
Looking for the realised and estimated price?
Description: 20th c., constructed from old wood, 46"h x 36"w x 37"d, door/opening: 13"h x 8"w
Condition Report: Good, finish distressed, structurally sound, chips, wood and paint loss
Provenance: Property from the Collection of a Recording Industry Executive, East Hampton, NY


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Saturday, October 25, 2008
West cacios
I dream of living on an island, with my dogs, and husband, but I will live there with or without him. It is something that at 53 years old I feel I really need to do. I just need to find out if I can live off $750.00 a month.
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Piggydb V6.0-dev5 – On-the-Spot Edit for File Fragments
Posted: June 28, 2012 Filed under: uncategorized 5 CommentsThis release updates the "Edit this fragment" button in the fragment tool bar to support on-the-spot editing for file fragments:
5 Comments on "Piggydb V6.0-dev5 – On-the-Spot Edit for File Fragments"
It seems that there is no way now to edit the title of an existing file-fragment.
I also miss the ability to tag a file-fragment (like you could in previous versions), hopefully already on your list.
Many thanks for a great tool!


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I just love crafty food! I needed an angel, and cutting out a sandwich with my angel shaped cookie cutter just wasn't scratching my creative itch. It took me longer to come up with a way to make edible angels then I though it would, but here they are in all their glory!
Making Your Angel Snack:
Bugle– for her dress
Oyster Cracker– for her head
Pretzel– for her wings
Cheerio– for her halo


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Sardines is a project by Jacques Le Bailly aka Baron von Fonthausen. This original version is the one that saw the light as a monospaced font student project and which would eventually grew into Vette Letters' largest font family (see VLNL Neue Sardines).
While most of our type is market-fresh, this one comes out of the can, but it's delicious nonetheless. And it's great for adventurous BBQ-ing!


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A Model From One Of The Design Indaba Fashion Shows
(Love The Hair!)
The Design Indaba Expo 2010 was open to the public and was held from Friday 26 February to Sunday 28 February.A chock-a-block daily programme of additional activities will fuel the buzz. All-day fashion shows, a short-film festival, the new Design Indaba Kids workshops, a suave designer bar, tantalising designer food and daily Pecha Kucha presentations by leading local creative artist are just some of the highlights to look forward to. Check out some of the fabulous photos below:
International Design All Stars from every discipline under the sun have been showing off their inventive prowess at the Design Indaba Conference since 1995. Drawing fans from creative, corporate and educational sectors alike, the conference has become the playing field for the imaginative at heart. Even one of my favorite entrepreneurs do-it-yourself mavens Martha Stewart was there and I'm sure she will feature the event on her television show.
(Photos:Michelly Rall)


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| Thread Tools |
13th February 2005, 21:03 | #1 |
Member Join Date: Mar 2004
Posts: 15,738
| Only "good" Pentium 4s have EM64T enabled ONLY THE CYNICAL survive. Long after they are supposed to, probably. Intel has told everyone on the record now that it will soon switch all of its desktop processors over to support for 64-32 extensions - or iAMD64 as we dub it. How will it do this? Well, the engineers at a fab will throw a switch and the number of the processors will change so that a 531 - a 3GHz Pentium 4 - will be exactly identical to a 530 except EM64T will be switched on. So how do you tell whether the Pentium 4 3GHz you are buying, or going to buy, be enabled for EM64T or not? You'd better ask the supplier that. If you get a satisfactory answer, let us know, because we reckon the average sales assistant won't have an earthly what you're talking about. Just in case, print out and take along the latest INQUIRER crib sheet, so you can make it crystal clear to her or to him. We often get letters from readers at the INQUIRER who obviously don't work for large corporate organisations so don't have ready access to the online sites Intel and others make available to their cronies, sorry customers and partners. Some of our readers try and do smart things like pull a fast one on the sales assistant by showing they have advanced knowledge of future plans. Plainly this is not a very good idea, because you only help make the sales assistant look small, and theyre probably working for a pittance anyway. Retail shops have an entirely different agendum to corporate customers. Often, they can get preferential buying prices from the IT suppliers, but that doesnt mean they need or even necessarily want to know whats coming on down the line three or six months in advance. No. What exercises the buyers here is the price they can get for the kit, how quickly the kit can be sold, and what they can get away with. They will find themselves committed to stock and have to deal with the general public. And you all know how difficult we can all be, when haggling. So our advice to you - if you are buying microprocessors separately or as part of a system - is to wait your turn like everyone else. If you insist on buying early, you will inevitably pay over the odds. Youll probably regret it too, because youll be at the bleeding edge of your credit card. And there will be always something coming down the line that will cause you to rend your hair, gnash your teeth, and tear up your clothes. Dont be an IT fashion victim. Just carry on reading the INQ. Here's the latest crib sheet. Ask the sales assistant about what difference big caches make too. But don't ask them about dual cores. You can probably do that next year, once all the stock has shifted http://www.theinquirer.net/?article=21233
__________________ lazyman Opteron 165 (2) @2.85 1.42 vcore AMD Stock HSF + Chill Vent II |
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Found some pictures of the Fenix HL30. Looks interesting. Im looking forward to when it comes out.
Found some pictures of the Fenix HL30. Looks interesting. Im looking forward to when it comes out.
Last edited by arizona1; 02-16-2012 at 08:42 AM.
Weight 86g. without batteries, spec. two AA batteries, TIR optics. Аnnouncement soon.
I remember a 2XAA fenix headlamp that never came out. I really wanted it so maybe this one will fit the bill but like the first I am not getting my hopes up until it is for sale.
Those red one,Is that laser thing?
No, that 4mm red LED.
Last edited by a_b; 02-24-2012 at 10:58 AM.
They have a 4 cell AA battery headlamp. How does the new compares to the old?
You mean 5mm red Led
Zebralight Spark Princeton Inova Petzl Maglite Bushnell 4 XM-L MagMod and a lot of Cree XM-L Lights Nitecore i4 Intellicharger Intl-outdoor 3400 Panasonic 3100 Bare and protected Samsung 3000 Sanyo 2600
Please, respect the planet, dont kill animals...
Looks like poorly built POS, probably will cost around 40$ while be worth 10$ in real life.
Just look at those pictures from the other site, it looks cheap and the person, who made those pictures complains regarding battery cover, pivot mechanism.
Waiting for Fenix to understand the utility of a flood light. They seem stuck on spot headlamps.
del post pls.....
Last edited by Dface; 03-01-2012 at 01:46 AM.
Thank you very interesting review, it is a pity that in Russian
Interesting flashlight. We wait for production models, and full review!
I hope that soon there will be in English!
p.s. they have found about the Fenix RC10
Last edited by Dface; 03-10-2012 at 12:00 AM.
HL30 beamshots here http://fonarik.com/test/?model=256&scene=2&mode=0
Hard to say for sure, they're got the beam aimed in a really unhelpful angle... looks like it's half on the corner of the wall, and half projecting down the hallway, making it virtually impossible to get a good idea of what the beam profile is like.
I also agree with Bolster on his comment about Fenix and their obsession with throwy headlamps... don't they get that most people use a flood beam for a headlamp rather than a spot beam?
What? Me? Derail a thread?
I'd rather have a spot headlamp with a good diffuser for flood.
you know me too i guess. but i also wish headlamp makers would figure out that for the average user, even though spot and flood are both needed, flood is what is needed more often and spot is only used sporadically. most headlamps that are available now sort of have flood as an afterthought. these guys need to spend more time working on the diffusers and making the flood beam fit to be the primary beam option.
If I need a light with throw, that's what my EDC light or other pocket light is for.
What? Me? Derail a thread?
yeah i guess, but it does get kind of tiring having to reach down to my pack to unclip or unholster my handheld light every single time i need a spot beam. it's just so much easier if i can just flick a button on my headlamp for that. plus when i'm backpacking, i really don't want to carry any extra weight. i just want my headlamp, a fauxton for backup and that's it.
Ah... someone who's never been in the middle of nowhere and had his headlamp fail! For backpacking trips I always carry two headlamps and two handheld lights. Lights like ZL's are small and light enough now days that I don't consider it an issue. I'd much rather carry another 4 oz. for two more lights and not need them, than need them and not have them because I was being a weight weenie... (nothing personal intended there Robo... )
About 20 years ago I was on a backpacking trip in the Wind River mountains in Wyoming with my girlfriend and a few other friends. We had base camped at a lake at about 9,000 ft. The crappy Princeton Tec headlamp I had at the time crapped out and I didn't have a backup, and we were about a three day hike from anywhere. That truly sucked a$$. I'll never make that mistake again.
What? Me? Derail a thread?
My biggest light-hog is my camera.
you'd be wrong there. i have. i had a PT Pulsar with me then, a 6 lumen model. i was fine.
i don't know what you do at night on your backpacking trips but all i do is cook, eat, clean, take a deuce, gaze at some stars, and go to sleep. fauxton works just fine for all that.
I've hiked/backpacked overnight tons and probably 95% of the time all I had was an AA minimag literally since I was in elementary to last year lol! (I'm 33... not the exact same light though, I think I lost a few along the way). I guess my backup was my buddies light or whoever was with me. But in all that time I have never left the campsite once after dark, nor needed a backup. Nothing wrong with night hiking thats cool, I just like hiking during the day so I can enjoy the scenery. Night time is for the campfire, a hot drink and rest, for me. But even if you dont night hike an emergency could always arise forcing you to hike out in the middle of the night or something like that. Next time I go out I'll atleast have my ZL and shopping for a second light (or primary) now.
Light weight hiking for me would be two zebralights and a Thrunite TI around my neck (just in case)!
I've I'm using the plastic 3AAA kind of headlamps I would appreciate a decent shot and decent flood beam. Usually the spot beam isn't decent and I end up diffusing it and not having a real spot beam. I'd like an optic for the spot with diffused edges.
I hate hiking with a spot where there is that moving halo outer circle of light. An optic where the edges are diffused is much better and then either a sliding diffuser or a secondary flood beam is nice. No one does this well however.
I don't think the designers actually use the lights they design. The BD Storm is a good light but is an example of the designers not being outdoor people IMO.
I know many people subscribe to the hand held spot and headlamp flood school of though (and I do as well when weight isn't an issue) I find it annoying that a headlamp can't do it all when needed. I just got an older Petzl XP that does that to an extent except that it's just underpowered by todays standards.
I have two Zebralight H51's...one H51 and one H51f. I use the H51f all the time and diffused the H51 so there is little difference between the two. The H51 is no thrower with the small head and XP-G ...it's just annoying if it's not diffused.
Last edited by gcbryan; 03-09-2012 at 07:09 PM.
I am buying this for sure! and prob in diferent colors for the family
Fenix: E01 - E05 - E11 - E15 - E25 - MC10 - HL21 - HL30 - LD01 - LD10 R5 - LD12 R5 - LD20 R2 - LD22 - PD10 - PD20 Q5 - PD20 R5 - PD22 - PD30 Q5 - PD30 R2 - PD31 - PD32 - PD32 T6 - RC10 - TK11 R2 - TK12 - TK20 - TK21 - TK22 - TK30 - TK41 - TK70


text:
FDA Panel Backs Novo Nordisk Insulinâ"GLP-1 Combination IDegLira »
"SILVER SPRING, MD â" A US Food and Drug Administration (FDA) advisory committee has given its blessing to a new injectable that combines fixed doses of a long-acting basal insulin with a glucagonlike peptide 1 (GLP-1) receptor agonist for diabetes"...
Read the FDA Panel Backs Novo Nordisk Insulinâ"GLP-1 Combination IDegLira article »
APIDRA is indicated to improve glycemic control in adults and children with diabetes mellitus.
Dosage Considerations
APIDRA is a recombinant insulin analog that is equipotent to human insulin (i.e. one unit of APIDRA has the same glucose-lowering effect as one unit of regular human insulin) when given intravenously. When given subcutaneously, APIDRA has a more rapid onset of action and a shorter duration of action than regular human insulin.
The dosage of APIDRA must be individualized. Blood glucose monitoring is essential in all patients receiving insulin therapy.
The total daily insulin requirement may vary and is usually between 0.5 to 1 Unit/kg/day. Insulin requirements may be altered during stress, major illness, or with changes in exercise, meal patterns, or coadministered drugs.
Subcutaneous Administration
APIDRA should be given within 15 minutes before a meal or within 20 minutes after starting a meal.
APIDRA given by subcutaneous injection should generally be used in regimens with an intermediate or long-acting insulin.
APIDRA should be administered by subcutaneous injection in the abdominal wall, thigh, or upper arm. Injection sites should be rotated within the same region (abdomen, thigh or upper arm) from one injection to the next to reduce the risk of lipodystrophy [See ADVERSE REACTIONS].
Continuous Subcutaneous Infusion (Insulin Pump)
APIDRA may be administered by continuous subcutaneous infusion in the abdominal wall. Do not use diluted or mixed insulins in external insulin pumps. Infusion sites should be rotated within the same region to reduce the risk of lipodystrophy [See ADVERSE REACTIONS]. The initial programming of the external insulin infusion pump should be based on the total daily insulin dose of the previous regimen.
The following insulin pumps† have been used in APIDRA clinical trials conducted by sanofiaventis, the manufacturer of APIDRA:
- Disetronic® H-Tron® plus V100 and D-Tron® with Disetronic catheters (Rapid™, Rapid C™, Rapid D™, and Tender™)
- MiniMed® Models 506, 507, 507c and 508 with MiniMed catheters (Sof-set Ultimate QR™, and Quick-set™).
Before using a different insulin pump with APIDRA, read the pump label to make sure the pump has been evaluated with APIDRA.
Physicians and patients should carefully evaluate information on pump use in the APIDRA prescribing information, Patient Information Leaflet, and the pump manufacturer's manual. APIDRA-specific information should be followed for in-use time, frequency of changing infusion sets, or other details specific to APIDRA usage, because APIDRA-specific information may differ from general pump manual instructions. Failure to follow APIDRA-specific instructions may lead to serious adverse events.
Patients administering APIDRA by continuous subcutaneous infusion must have an alternative insulin delivery system in case of pump system failure.
Based on in vitro studies which have shown loss of the preservative, metacresol and insulin degradation, APIDRA in the reservoir should be changed at least every 48 hours. APIDRA should not be exposed to temperatures greater than 98.6°F (37°C). In clinical use, the infusion sets and the APIDRA in the reservoir must be changed at least every 48 hours [See WARNINGS AND PRECAUTIONS and HOW SUPPLIED/Storage and Handling].
Intravenous Administration
APIDRA can be administered intravenously under medical supervision for glycemic control with close monitoring of blood glucose and serum potassium to avoid hypoglycemia and hypokalemia. For intravenous use, APIDRA should be used at concentrations of 0.05 Units/mL to 1 Unit/mL insulin glulisine in infusion systems using polyvinyl chloride (PVC) bags. APIDRA has been shown to be stable only in normal saline solution (0.9% sodium chloride). Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Do not administer insulin mixtures intravenously.
Dosage Forms And Strengths
APIDRA 100 units per mL (U-100) is available as:
- 10 mL vials
- 3 mL SoloStar prefilled pen
Storage And Handling
APIDRA 100 units per mL (U-100) is available as:
10 mL vials NDC 0088-2500-33
3 mL SoloStar prefilled pen, package of 5 NDC 0088-2502-05
Pen needles are not included in the packs.
Solostar is compatible with all pen needles from Becton Dickinson and Company, Ypsomed and Owen Mumford.
Do not use after the expiration date (see carton and container).
Unopened Vial/SoloStar
Unopened APIDRA vials and SoloStar should be stored in a refrigerator, 36°F-46°F (2°C-8°C). Protect from light. APIDRA should not be stored in the freezer and it should not be allowed to freeze. Discard if it has been frozen. Unopened vials/SoloStar not stored in a refrigerator must be used within 28 days.
Open (In-Use) Vial
Opened vials, whether or not refrigerated, must be used within 28 days. If refrigeration is not possible, the open vial in use can be kept unrefrigerated for up to 28 days away from direct heat and light, as long as the temperature is not greater than 77°F (25°C).
Open (In-Use) SoloStar prefilled pen
The opened (in-use) SoloStar should NOT be refrigerated but should be kept below 77°F (25°C) away from direct heat and light. The opened (in-use) SoloStar kept at room temperature must be discarded after 28 days.
Infusion sets
Infusion sets (reservoirs, tubing, and catheters) and the APIDRA in the reservoir must be discarded after 48 hours of use or after exposure to temperatures that exceed 98.6°F (37°C).
Intravenous use
Infusion bags prepared as indicated under DOSAGE AND ADMINISTRATION are stable at room temperature for 48 hours.
Preparation And Handling
After dilution for intravenous use, the solution should be inspected visually for particulate matter and discoloration prior to administration. Do not use the solution if it has become cloudy or contains particles; use only if it is clear and colorless. APIDRA is not compatible with Dextrose solution and Ringers solution and, therefore, cannot be used with these solution fluids. The use of APIDRA with other solutions has not been studied and is, therefore, not recommended.
sanofi-aventis U.S. LLC Bridgewater, NJ 08807 A Sanofi Company. Date of revision: 05/2014
This monograph has been modified to include the generic and brand name in many instances.Last reviewed on RxList: 6/2/2014
Apidra FDA Prescribing Information
Additional Apidra Information
Apidra - User Reviews
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find tips and advances in treatment.


text:
List Price: US$ 140.00
46% of customers buy the item featured on this page.
Silhouette: A-Line/Princess
Neckline: V-neck
Hemline/Train: Asymmetrical
Fabric: Chiffon
Embellishment: Ruffle, Beading
Straps: Spaghetti Straps
Sleeve: Sleeveless
Back Style: Zipper Up
Fully Lined: Yes
Built-In Bra: Yes
Boning: Yes
Shown Color: Daffodil
Size: General, Plus
Season: Spring, Summer
Model's Dress Size: US 2 / UK 6 / EU 32
Model Information: Height:5.8ft Bust:33in Waist:24in Hips:34in
The dress does not include any accessories in the picture, such as wraps/jackets, gloves, veil, handbag, etc. You may contact us to order the accessories separately.
Tailoring Period: 9-11 days. See Details >>
Weight: 1000g
Shipping To:
Delivery Methods | Delivery Time | Delivery Cost | |
Expedited Shipping | 3-6 Days | US$ 16.99 (70% OFF) | |
Standard Shipping | 5-8 Days | US$ 0.00 (Free!) |
By Susan
Hi Susan,
Thank you very much for your mail.
Please check the attachment for the pictures of the dress we made before.
Could you kindly tell us do you have any other requirements for this dress?
We are looking forward to your reply.


text:
Winter Park Wipeout [1]
Submitted by Sophie Goodman on Thu, 02/04/2016 - 2:18pm
Are you up for sledding, puzzle solving, and zany games? You'll have three hours to complete as many challenges as you can in this fun competition, earning party beads along the way. Then stick around for the after-party to enjoy beer, hot cocoa, and food from local vendors. Sat 2 p.m.
Content Category:
- Events [2]
Event Category:
Event Date
April 2 2016, 2:00 PM
Event Cost
Event URL
Event Venue
Winter Park Ski Resort
More Info
Visit winterparkwipeout.com [5].
Editor's Pick


text:
Wolf Blitzer delivers the most important breaking news and political, international, and national security stories of the day. Tune to The Situation Room weekdays 5-7pm ET on CNN.
As the Obama administration weighs airstrikes against ISIS terrorists in Syria, officials are concerned at the jihadist group's growing strength, impressive tacticts and "uncanny" discipline. Brian Todd reports on ISIS becoming stronger and more capable.
Brian also took to Twitter to answer your questions on ISIS. Here's a recap.


text:
Dear Shoppers, We are undergoing a company-wide computer system upgrade, and the inventory levels listed on our website may not accurately reflect what is actually on our shelves. Please give us a call at 303-322-7727 and a bookseller will be happy to check stock for you. We apologize for the inconvenience.
The Adventures of Huckleberry Finn (Paperback)
Running away seemed like a good idea at the time...
The Widow Douglas is doing her best to civilise Huckleberry Finn, but it just isn't working. Wearing clean clothes, going to school, and having a hot meal waiting for him when he gets home are becoming boring and tedious.
So, to make his life more interesting Huck, as he is normally called, decides to join Tom Sawyer's gang of outlaws. However, when they fail to be the vicious ransom specialists they claim to be, Huck decides to forget about excitement and tries to give his civilised life another go. He attends school and minds his own business... for a while.
After his father turns up out of the blue and starts causing trouble, Huck decides he's had enough of normal life and sets sail on his raft for a secluded island. When he arrives he finds he's not the only one who has decided to live there. On the island, he encounters thieves, a flood that provides a nice surprise, con men, violent shootouts, family feuds and much more.
After so much adventure, Huckleberry Finn ends up wishing he was back at home, tucked up in bed after a hot meal. But does this wish come true, or do his adventures continue?
About the Author
Samuel Langhorne Clemans, known to most as Mark Twain, has been hailed by many as the father of American Literature. His two most famous works, The Adventures of Tom Sawyer (1876) and The Adventures of Huckleberry Finn (1884), are considered two of the greatest American novels of all time. Twain was born in Florida, Missouri on 30th November 1835. He grew up in the town of Hannibal on the Mississippi River, which would eventually serve as the basis for the place where Tom Sawyer and Huckleberry Finn would live. Twain grew up in Missouri at a time when it was a slave state. After the American Civil War broke out, he became a strong supporter of emancipation, and staunchly believed that the slave trade should be abolished. Though he began as a comic writer, the tribulations he faced in his personal life perhaps served to turn him into a serious, even pessimistic, writer in his later years. He lost his wife and two daughters, and his ill-fated life never really allowed him to recover. Twain passed away in 1910, but he is still one of the best-loved writers around the world.
Praise For…
This slender graphic adaptation of the Great American Novel preserves some of Twain's language, most of his plot and a good sense of his sardonic take on human society. Mixing dialogue balloons with enough boxed narrative to evoke Huck's distinctive voice, Mann packs in all of the major incidents and tones down at least some of the violence — the two con men are only "punished" here rather than specifically tarred and feathered, for instance. Similarly, though Huck gets viciously slapped around by his father in the pictures, in general there isn't much other blood visible. . . . A good choice for readers who aren't quite up to tackling the original, with perfunctory but well-meant notes on Twain's life and the history of slavery in the United States. Co-published with its prequel, The Adventures of Tom Sawyer.
— Kirkus Reviews
"I highly recommend Campfire's comics. They do what they are intended to do and do it in a way that excites kids about classic literature."
— Chris Wilson, The Graphic Classroom (a resource for teachers and librarians)


text:
If you are making a visit to laid back Austin, Texas, the best way to get around town is on a scenic carriage ride. There are several to choose from and depending on what you want to see and how long you have to devote to touring, you can have your pick at the four packages currently available.
If taking a peek at the exquisite architecture that lines the streets of the city piques your interest, the Historic Homes Carriage Tour is just right for you. Along the way, you will visit one of the last Victorian blocks to remain nationwide, and there are more than ten 19th century homes lining this street. You will also see the Governor's Mansion and the Capitol Building on your travels. If what you are seeking is a quiet and romantic ride with a loved one, you will get just that. Alternatively, if you are looking for more of a guided and narrated ride, drivers are ready and willing to oblige.
The Grand Carriage Tour will take you down historic Congress Avenue where you will catch a glimpse of the largest and tallest Capitol in the US. You will visit the Victorian block as well, on your way to check out some of the other hot spots in the area. Ride along the Colorado River and pass through the famous entertainment district to get a taste of the talent and showmanship that exists throughout the city.
Other carriage rides in the area include the Capitol Carriage Tour and the Town Lake Carriage Ride. If you decide, however, that a carriage ride will not make your short list, the Austin in 90 minutes Tour will provide you with a well-narrated sightseeing journey around Austin by van, with views and background on the UT Performing Arts Center, Austin City Limits, O. Henry Museum, Zilker Park, and much more.
Winter is the perfect time to consider a visit to sunny Austin. While the temperatures dip down in these months, they are much milder than elsewhere, making it the ideal location for those who wish to warm up a little without stretching the budget and going international.
Visit www.austintours.us for more information on carriage tours and other options for your sightseeing excursion, Texas style.


text:
Brokenness refers to the situation whereby a website is made accessible in dual stack, meaning both IPv4 and IP6, using records referred to as A's for IPv4 and quad A's for IPv6. Some end-users can experience slower access to the website or in some rarer instances no access at all. Brokenness is mostly attributable to older versions of the Mac Os operating system. The brokenness issue has been very well described by Eric Vyncke in a posting on the Belgian IPv6 website and has been monitored by Tore Anderson from Norway who has been measuring the impact of dual stack on customer loss for more than a year and shows customer loss dropping considerably over the last twelve months.
When Google started to make some of their sites accessible in IPv6 a major concern was broken connections caused by ISP, CPE, firewall and OS issues. It was initially estimated to potentially affect around 0.5% of end-users which is obviously unacceptable for any major search and web browsing site.
The issue has been gaining in importance as the remaining IANA IPv4 address reservoir could be empty as early as February 2011 according to some experts speaking at last week's ARIN meeting. Google's Lorenzo Colliti provided some edifying updates [PDF] on Google's IPv6 deployment and the brokenness issue. Breakage for all clients was estimated at 0.082% and for white listed ISP's 0.014% excluding Mac OS X numbers are in the ' four nine's territory'.
The need to increase rapidly the amount of IPv6 accessible content is clearly a rapidly growing priority. Google, Limelight, Akamai where quite adamant restating their commitment to have content and hosted content IPv6 accessible. In the meantime, Eric Vynckes' compilation of IPv6 accessible website sites worldwide based on extraction of the top 50 websites per Top-Level Domain (TLD) from the Alexa list will help us us keep track of progress.
By the time ARIN meets next in April 2011, we might be able to offer a toast to the last free slash eight IANA could just have allocated and the Regional Internet Registry who got that last specimen.
By Yves Poppe, Director, Business Development IP Strategy at Tata Communications. (Any opinions, findings, conclusions or recommendations expressed in these articles are solely those of the author and are not in any way attributable to nor reflect any existing or planned official policy or position of his employer in respect thereto.)
Related topics: IP Addressing, IPv6, Regional Registries
To post comments, please login or create an account.
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text:
U.N. climate talks stall over rich-poor divisions
Updated 9:12 am, Thursday, March 7, 2013
Bonn, Germany --
U.N. climate talks ran into gridlock Thursday as a widening rift between rich and poor countries risked undoing some advances made last year in the decades-long effort to control carbon emissions that scientists say are overheating the planet.
As happens so often in the slow-moving negotiations, the session in Bonn bogged down with disputes over technicalities. But at the heart of the discord was the larger issue of how to divide the burden of emissions cuts between developed and developing nations. Developing nations say the industrialized world - responsible for most of the emissions historically - should bear the brunt of the emissions cuts while developed nations want to make sure that fast-growing economies such as China and India don't get off too easy. China is the world's top polluter.
"There is a total stalemate," said Artur Runge-Metzger, chief negotiator for the European Union.
Distrust, frustration
The negotiations in Bonn were meant to build on a deal struck in December in Durban, South Africa, to create a new global climate pact by 2015 that would make both rich and poor nations rein in emissions caused by the burning of oil and other fossil fuels. But on the next-to-last day of two weeks of talks there was little sign of progress, as different interpretations emerged on what, exactly, was agreed upon last year.
"There is distrust and there is frustration in the atmosphere," said Seyni Nafo, spokesman for a group of African countries.
The European Union says China and other developing countries are backsliding on commitments made in Durban to bring the discussion on emissions cuts from both rich and poor nations into one forum, instead of the current structure, which has two parallel negotiation tracks. Developing countries - backed by climate activists - accuse the United States, European Union and other industrialized nations of trying to evade commitments made in previous negotiations and shift responsibilities for tackling climate change to the developing world.
"Developed countries like the U.S., Japan, Canada and Russia ... have consistently blocked references to the existing legal principles, while continuing to ignore the fact that their meager emission cut targets expose the world's most vulnerable people to climate change's devastating effects," said Mohamed Adow, a senior climate change adviser at Christian Aid.
Talks have little impact
Since their launch in the early 1990s, the U.N. talks have had little success reducing emissions of the heat-trapping gases that a large majority of climate scientists say are warming the Earth, with potentially devastating consequences for poor countries ill-prepared to deal with rising sea levels, floods, droughts and other effects of a changing climate.
Actions taken and pledged so far fall well short of what the U.N. experts say is needed to achieve the goal of preventing global temperatures from rising more than 2 degrees Fahrenheit above current levels by the end of this century.
The only existing binding treaty, the 1997 Kyoto Protocol, was shunned by the United States because it doesn't impose any emissions targets on China, thus leaving out the two biggest carbon emitters on the globe. It was set to expire this year, but countries agreed in Durban to extend it, though they haven't agreed on how long.
Meanwhile, Canada, Japan and Russia have refused to make any new commitments under Kyoto, meaning it covers only about 15 percent of global emissions.


text:
The Navigator Continuous Glucose Monitoring System (Abbott) was approved by FDA this week. Would you ever consider going on a CGMS?
Yes, I am on one now. |
Yes, if my insurance would cover it. |
Not sure, I do not know enough about them. |
Not yet. The technology is not advanced enough. |
Never, who wants to be hooked up 24/7? |
No, but I never say never! |
ads keep dLife free
Recipe Shuffle
ads keep dLife free


text:
Bangalore: Toyota Kirloskar Motor Pvt Ltd (TKM) on Thursday announced the introduction of the all new Innova Aero (Limited Edition). (Agencies) Latest News from Business News Desk
Only 1,200 exclusive units of the Innova Aero will be on sale till December, 2012, it said in a statement.
The New Innova Aero is based on the existing GX Grade and is available in options of a seven seater and an eight seater. The Innova Aero is available in Euro III and Euro IV.
"The limited edition of the highly popular Innova is aimed at providing exclusivity to customers, by lending the vehicle a sporty edge.
"The Aero kit specially designed for the limited edition, enhances the overall appearance of the vehicle, lending it a refreshed look," it said.
The New Innova Aero comes in two colours - Super White and Silver Mica Metallic, Sandeep Singh, Deputy Managing Director (Marketing), TKM, said, while adding that "The new Innova Aero will provide new and unique ownership experience to customers who are looking for a trendy and sporty look".
The new Innova Aero is priced between Rs 12,25,677 and Rs 12,30,207 ex-showroom Delhi and will be available at all Toyota dealerships from Thursday.


text:
This summer we've embarked on a new project. Based on some conversations that arose during my Neural Engineering graduate course, we've decided to try growing neurons in multi-electrode array (MEA) dishes to record from them. The dish where we grow the neurons is set up with a series of electrodes built right into the dish. We are growing rat neurons in the dish and they are doing quite well - they have spontaneously started growing axons to interact with each other and we expect they will be sufficiently mature to record from within ten days.
The picture at right shows our neurons under the microscope in the MEA dish. The black traces are the wires and electrodes of the dish. The neurons are the dark spots and the little dark lines between neurons are the axons. This picture was taken on August 19, 2011.
Once we have this procedure established, we plan to explore whether these arrays of neurons can be 'trained' via stimulus protocols. In theory, repeated electrical stimuli can force the neurons to rearrange their connectivity in predictable patterns. In that sense the network can be said to "learn" the stimuli. This is effectively similar to creating a biological neural network.
In order to save money, we are developing our own in-house circuit for amplifying and digitizing the neural signals (as opposed to buying an off-the-shelf rig). The circuit is based off the amplifier I published in my dissertation (in 2004). We have designed a 10-channel PCB which we hope to send today to the fabrication facility.
More details to come as they emerge!


text:
Online Anthology of Lyrical Audio Poetry in Modern English, recorded by Walter Rufus Eagles ad majorem Dei gloriam
All spoken voice recordings on www.eaglesweb.com, its two front pages (index and default) and two alternate front page masters, and its 4,806 other files and directories, excluding image files and music files, are licensed under a Creative Commons License unless otherwise identified on one of the pages. eaglesweb.com poetry for the ear in the tradition of blind Homer
POEMA AD LIBITUM, Fortnight II (June 25 - July 8, 2004) chosen at the discretion of your reader, with his notes where appropriate.
Color Codes:
Blue = Newly recorded in Part II May 1, 2004 to April 30, 2006
Red = Replay from Part I May 1, 2002 to April 30, 2004
William Drummond of Hawthornden [1585-1649] [One of the English metaphysical poets represented on Eaglesweb.com] Three Sonnets: For the Baptist [0:59] Fair is my yoke, though grievous be my pains. . . [0:57] What doth it serve to see sun's burning face? [0:53]
Lewis Carroll [1832-1898][British] Jabberwocky (from Through the Looking Glass and What Alice Found There, 1872) [1:18] You Are Old, Father William [1:39]
Elizabethan Dramatist Thomas Dekker [1570?-1632]: another exact contemporary of Webster and Fletcher; see below. Golden Slumbers Kiss Your Eyes [recorded by the Beatles] The Merry Month of May [1:00]
W. H. Auden [1907-1973]British, then American]: As I Walked Out One Evening [2:05] Elegy as featured in the film Four Weddings and a Funeral [dedication of reading] [0:59] In Memory of W. B. Yeats [3:23] [See also the Yeats page.] Musee des Beaux Arts [1:15] [See also "Icarus" page.]
James Stephens [1881-1950][Irish]: In Waste Places [1:07] Hate [0:44] Coming soon: In the Cool of the Evening; I Heard a Bird at Dawn; In the Poppy Field.
John Webster [1578-1632][ English] An exact contemporary of John Fletcher, below, and like him, a dramatist. A Land Dirge ("Call for the robin red-breast and the wren" [0:31] All the Flowers of the Spring [0:43] Hark, Now Everything Is Still from The Duchess of Malfi [1:01]
[no picture]
John Fletcher [1579-1625] [British] A younger contemporary of Shakespeare and, like him, a dramatist. Terse, colorful and bittersweet. Melancholy [0:52] Care-Charming Sleep [0:42] Do Not Fear to Put Thy Feet [0:25] Lay a Garland on My Hearse [0:25] The "tragic sense of life" (Miguel de Unamuno) as it was known especially to the Elizabethans. See the Day Begins to Break [0:29]
Robert Herrick [1591-1674][English]: One of the English metaphysical poets represented on Eaglesweb.com Eternitie [0:27] The Poetry of Dress [1:25] To Blossoms [0:39] To Dianeme [0:32]
Ralph Waldo Emerson [1803-1882][American]: Brahma [0:50] Merlin [2:43] Concord Hymn [0:53] "Ralph Waldo Emerson, whose original profession and calling was as a Unitarian minister, left the ministry to pursue a career in writing and public speaking. Emerson became one of America's best known and best loved 19th century figures." -- Transcendentalists.com. I would call him Poet, Philosopher and Essayist in that order. - W.R .E.
Adelaide Crapsey [1878-1914] [American] Eight cinquains (five-line formal successor to the four-line quatrain), derived in literary form from the five-line Japanese waka, the parent of the three-line haiku form (for which latter, see my own example, below.) To understand this kind of poetry better, read a few haiku by each of the three classical poets: Basho, Buson and Sesshu. A web search will lead you to them. Part One (Triad, Dirge & Lonely Death) [1:22][Triad is her most famous cinquain] Part Two (November Night, Moon Shadows & The Guarded Wound) [0:50] Part Three (Amaze, The Warning [1:00] & an example from Percy Bysshe Shelley, embedded in his To a Skylark) [3:44]
Hear Carl Sandburg [1878-1967]: Adelaide Crapsey from Cornhuskers, 1918 [0:54] [note]: The great North American Poet was responsible for making certain the beautiful young schoolteacher-poet (who died of complications of tuberculosis at age thirty seven) took her place in the pantheon of our best English language poets. - W.R.E.
Posted June 30, 2004 0100 GMT: Origami executed in Adobe Photoshop 7.0 on June 30, 2004. Haiku executed 1956. Click HERE for audio version recorded June 30, 2004 0202 GMT Walter Rufus Eagles [1934- ]
Erasmus Darwin [1731-1802][English Poet, Scientist & Educator]: Visit of Hope to Sydney Cove, near Botany Bay [1:47] The poet was grandfather of Charles Darwin. He was a rare polymath whose mind traveled over many areas of learning with permanent effect on each. Click HERE to read an example of his thinking concerning evolution two generations before Charles Darwin. - W.R.E.
Sassoon, Siegfried [1886-1967][British]: A Whispered Tale [1918][0:55]; Repression of War Experience [1918][2:11]; The Poet as Hero [1918][0:52] and Counter-Attack [1918][2:25] Listen to Wilfrid Owen's Wild with All Regrets dedicated to Siegfried Sassoon [2:21]. Like Robert Graves, Sassoon survived the war and went on to develop his poetic talent. More's the pity that these did not: Wilfrid Owen, Rupert Brooke, Joyce Kilmer, Alan Seeger, John McCrae, W. N. Hodgson, Isaac Rosenberg and Edward Thomas. Visit the memorial for these War Dead Poets and also British, American and Canadian War Poets. - W.R.E.
Samuel Taylor Coleridge [1772-1834] [British]: Kubla Khan [2:31] Coleridge, like Keats, suffered great pain during his life and became addicted to opium, one of the early painkillers. He claimed that this poem was written "under the influence." Let it be noted that in his time, the circumstances of his life and his addiction were not unusual. - W.R.E.
T. S. Eliot [1888-1965][American, then British]: The more serious side of Eliot: - W.R.E. The Death of St. Narcissus [2:06] Journey of the Magi [2:17] La Figlia Che Piange (The Weeping Girl) [1:13] The Love Song of J. Alfred Prufrock [6:41] Morning at the Window [0:32]
T. S. Eliot [1888-1965]:Three Poems from The Old Possum+'s Book of Practical Cats The Naming of Cats [1:47] The Old Gumbie Cat [2:16] Old Deuteronomy [2:16] + A pseudonym employed by Eliot based on a nickname ('The Old Possum') given to him by his friend Ezra Pound. Tomorrow, the more serious side of Eliot. - W.R.E.
For if we may compare infinities, it would seem to require a greater infinity of power to cause the causes of effects, than to cause the effects themselves. This idea is analogous to to the improving excellence observable in every part of the creation; such as in the prgressive increase of the solid or habitable parts of the earth from water; and in the progressive increase of the wisdom and happiness of its inhabitants; and is consonant to the idea of our present siutation being a state of probation, which by our exertion we may improve, and are consequently responsible for our actions. [Erasmus Darwin, Zoonomia, vol. 1 (London: 1794) 509.]
Click HERE to go back to POEMA AD LIBITUM, Fortnight I (June 10 - June 24 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight III (July 9 - July 22, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight IV-V (July 23 - August 19, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight VI (August 20 - September 2, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight VII (September 3 - September 16, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight VIII (September 17 - September 30, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight IX (October 1 - October 14, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight X (October 15 - October 28, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight XI (October 29- November 11, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight XII (November 12- November 25, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight XIII (November 26 - December 9, 2004) Click HERE to go forward to POEMA AD LIBITUM, Fortnight XIV (December 10 - December 23, 2004)
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Auguste RodinNear the end of his life, the master sculptor Auguste Rodin (1840-1917) hired the poet Rainer Maria Rilke to serve as his secretary. Intensely sensitive to art and able to express this awareness in prose of great lyricism and clarity, in 1903 Rilke published a profound meditation on the unique power of Rodin's sculpture. Written around a chronology of Rodin's work, it is also an introduction to some of the greatest sculpture of the 19th century. A translation was soon produced by the American poet and artist Jessie Lemont. Unavailable for many years, this translation is reprinted here together with Rilke's original illustrations. |
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text: December 15, 2015 Space Opera Tagged: Theme When Radio was the principal medium of home entertainment in the USA, daytime serials intended for housewives were often sponsored by soap-powder companies; the series were thus dubbed "soap operas". The name was soon generalized to refer to any corny domestic drama. Westerns were sometimes called "horse operas" by false analogy, and the pattern was extended into sf terminology by Wilson Tucker in 1941, who proposed "space opera" as the appropriate term for the "hacky, grinding, stinking, outworn, spaceship yarn". It soon came to be applied instead to colourful action-adventure stories of interplanetary or interstellar conflict. Although the term still retains a pejorative implication, it is frequently used with nostalgic affection, applying to space-adventure stories which have a calculatedly romantic element. The term might be applied retrospectively to such early space adventures as Robert W Cole's The Struggle for Empire (1900) – a remarkable precursor of the interstellar war epic – but, as it was coined as a complaint about Pulp Cliché, it seems reasonable to limit its use to Genre SF. Five writers were principally involved in the development of space opera in the 1920s and 1930s. E E "Doc" Smith made his debut with the exuberant interstellar adventure The Skylark of Space (August-October 1928 Amazing; 1946), and continued to write stories in a similar vein until the mid-1960s; two sequels, Skylark Three (August-October 1930 Amazing; 1948) and Skylark of Valeron (August 1934-February 1935 Astounding; 1949), escalated the scale of the action before the Lensman series took over, the Spaceships growing ever-larger and the Weapons more destructive until Galactic Empires were toppling like card-houses in Children of the Lens (November 1947-February 1948 Astounding; 1954). Once there was no greater scale of action to be employed, Smith had little more to offer, and his last novels – The Galaxy Primes (March-May 1959 Amazing; 1965) and Skylark DuQuesne (June-October 1965 If; 1966) – are hardly more than exercises in recapitulation. In the 1970s, however, a reissue of the Lensman series enjoyed such success with readers that Smith's banner was picked up by William B Ellern, David A Kyle and Stephen Goldin (see E E Smith for details). Contemporary with Smith's first interstellar epic was a series of stories written by Edmond Hamilton for Weird Tales, beginning with "Crashing Suns" (August-September 1928 Weird Tales) and ultimately collected as Crashing Suns (stories August 1928-November 1930 Weird Tales; coll 1965) and Outside the Universe (July-October 1929 Weird Tales; 1964). Although he was a more versatile writer than Smith, Hamilton took great delight in wrecking worlds and destroying suns, and his name was made with space opera (he too continued to write it until the 1960s), other early examples being "The Universe Wreckers" (May-July 1930 Amazing) and the Captain Future series. In the late 1940s Hamilton wrote The Star of Life (January 1947 Startling; 1959) and the memorable The Star Kings (September 1947 Amazing; 1949; vt Beyond the Moon 1950), an sf version of The Prisoner of Zenda (1894) by Anthony Hope. The last of Hamilton's works in this vein were Doomstar (1966) and the Starwolf trilogy (1967-1968). Even before Smith and Hamilton made their debuts, Ray Cummings was writing interplanetary novels for the general-fiction pulps and for Hugo Gernsback's Science and Invention. His principal space operas were Tarrano the Conqueror (July 1925-August 1926 Science and Invention; 1930), A Brand New World (22 September-27 October 1928 Argosy All-Story Weekly; 1964), Brigands of the Moon (March-June 1930 Astounding; 1931) and its sequel Wandl, the Invader (February-May 1932 Astounding; 1961), but his reputation was made by his microcosmic romances (see Great and Small), and it was to such adventures that he reverted when he turned to self-plagiarism in later years. The two most important writers who carried space opera forward in the wake of Smith and Hamilton were John W Campbell Jr and Jack Williamson. Campbell made his first impact with the novelettes collected in The Black Star Passes (coll of linked stories 1953), and he went on to write Galaxy-spanning adventures like Islands of Space (Spring 1931 Amazing Stories Quarterly; 1957), Invaders from the Infinite (Spring 1932 Amazing Stories Quarterly; 1961) and The Mightiest Machine (December 1934-April 1935 Astounding; 1947). Campbell had a better command of scientific jargon than his contemporaries, and a slicker line in superscientific wizardry, but he began writing a different kind of sf as Don A Stuart and subsequently abandoned writing altogether when it clashed with his duties as editor of Astounding Science-Fiction. Williamson flavoured space opera with a more ancient brand of romanticism, basing characters in The Legion of Space (April-September 1934 Astounding; rev 1947) on the Three Musketeers and Falstaff; although he soon moved on to more sophisticated varieties of exotic adventure, he never quite abandoned space opera: Bright New Universe (1967) and Lifeburst (1984) carry forward the tradition, and his collaborations with Frederik Pohl, such as The Singers of Time (1991), retain a deliberate but deft romanticism which places them among the best modern examples of the species. Another notable space opera from the 1930s is Clifford D Simak's Cosmic Engineers (February-April 1939 Astounding; rev 1950). During the 1940s some of the naive charm of space opera was lost as standards of writing rose and plots became somewhat more complicated, and the trend was towards a more vivid and lush romanticism. Notable examples are Judgment Night (August-September 1943 Astounding; title story of coll 1952; separate publication 1965) by C L Moore and several works by A E van Vogt, including The Mixed Men (stories September 1943-January 1945 Astounding; fixup 1952; cut vt Mission to the Stars) and Earth's Last Fortress (March 1942 Astounding as "Recruiting Station"; vt as title story of Masters of Time coll 1950; 1960 dos). By this time the Galactic-Empire scenario was being used for other purposes, most effectively by Isaac Asimov in the Foundation series (stories May 1942-January 1950 Astounding; fixups 1951-1953); by the 1950s it had become a standardized framework available for use in entirely serious sf. Once this happened, the impression of vast scale so important to space opera was no longer the sole prerogative of straightforward adventure stories, and the day of the "classical" space opera was done. But Asimov, like many others, retained a deep affection for old-fashioned romanticism, deploying it conscientiously in The Stars Like Dust (1951). Many of the more "realistic" space adventures of the 1950s incorporate space-operatic flourishes, including James Blish's Earthman, Come Home (April 1950-November 1953 var mags; fixup 1955; cut 1958), which features space battles between star-travelling cities – although the other novels in the Okie series have rather different priorities. The old-style space opera seemed rather juvenile by this time, but it remained an important component of the fiction published by the more downmarket pulps while they were still being published, especially Planet Stories and Thrilling Wonder Stories. New life could still be breathed into it by the better writers associated with those magazines; prominent were Leigh Brackett, as in The Starmen (1952), and Jack Vance, as in The Space Pirate (1953; cut vt The Five Gold Bands 1963; text restored 1980). There were Digest magazines which specialized in exotic adventure stories, including space operas – notably Imagination and the second of the two US magazines entitled Science Fiction Adventures (which survived as a UK magazine for some years after its death in the USA) – but they did not long outlast the pulps. When it was abandoned by the magazines, space opera found a new home in the Ace Books Doubles edited by Donald A Wollheim (see also Dos). Robert Silverberg published a good deal of colourful material in this format, including the trilogy assembled as Lest We Forget Thee, Earth (fixup 1958) as by Calvin M Knox, while Kenneth Bulmer, John Brunner and E C Tubb became UK recruits to this largely US tradition, the last-named labouring to preserve it with his long-running Dumarest series. Space-operatic romanticism is still widely evident, usually cleverly combined with other elements. Twentieth-century examples include Gordon R Dickson's long-running Dorsai series, Poul Anderson's Ensign Flandry series, H Beam Piper's Space Viking (1963), Michael Moorcock's The Sundered Worlds (fixup 1965; vt The Blood Red Game), Ian Wallace's Croyd (1967) and Dr Orpheus (1968), Samuel R Delany's Nova (1968), Alan Dean Foster's The Tar-Aiym Krang (1972) and its sequels, Barrington J Bayley's Star Winds (1978), Philip José Farmer's The Unreasoning Mask (1981), S P Somtow's Light on the Sound (1982) and its sequels, F M Busby's Star Rebel (1984) and its sequels, Ben Bova's Privateers (1985), Mike Resnick's Santiago (1986), Iain M Banks's Consider Phlebas (1987) and other Culture novels, Colin Greenland's Take Back Plenty (1990), Stephen R Donaldson's Gap series, begun with The Gap into Conflict: The Real Story (1990) – which transfigures Wagner's Ring Cycle of real operas – Simon R Green's light-hearted Deathstalker sequence beginning with Deathstalker (1995), and Linda Nagata's Vast (1998). The tradition continues in the present century with Alastair Reynolds's Inhibitors sequence opening with Revelation Space (2000), Charles Stross's Singularity Sky (2003), Neal Asher's Orbus (2009), further popular Culture novels by Iain M Banks such as Surface Detail (2010), Michael Cobley's Humanity's Fire sequence opening with Seeds of Earth (2009), and many more. A romantic, feelgood approach to space opera informs Becky Chambers's The Long Way to a Small, Angry Planet (2014). The subgenre seems in no danger of losing its popularity, given the winning of Hugo awards by space operas like C J Cherryh's Downbelow Station (1981), David Brin's Startide Rising (1983), Lois McMaster Bujold's The Vor Game (1990), Barrayar (1991) and Mirror Dance (1994), and Vernor Vinge's A Fire Upon the Deep (1992) and A Deepness in the Sky (1999). Relevant Nebula winners include David Brin's Startide Rising again, Greg Bear's Moving Mars (1993) and Catherine Asaro's The Quantum Rose (2000). The traditional crudities of space opera – generally abandoned by modern practitioners – are easily parodied by such comedies as Harry Harrison's Bill, the Galactic Hero (December 1964 Galaxy as "The Starsloggers"; exp August-October 1965 New Worlds; 1965) and Star Smashers of the Galaxy Rangers (1973), M John Harrison's darkly sardonic The Centauri Device (1974) and Douglas Adams's Hitch-Hiker books, but the affection in which it is held defies total deflation – as evidenced by the later (though greatly inferior) Bill, the Galactic Hero series of Shared-World adventures. The television series Star Trek has given rise to a long-running series of spinoff novels, many of which are more space-operatic than the studio budget ever permitted the television scripts to be; the Star Wars franchise, also hugely productive of novelizations, established space opera as a major contender in late twentieth-century cinema. An excellent theme anthology is Space Opera (anth 1974) edited by Brian W Aldiss; his Galactic Empires (anth 1976 2vols) is also relevant. Jack Vance borrowed the term for Space Opera (1965), but with tongue in cheek: the novel records the adventures of a spacefaring opera company (see Music). [BS/DRL] see also: Fantastic Voyages; Homeworld; Mass Effect; Space Flight; Star Control; Starflight; Traveller. Previous versions of this entry 10/10/2011 21/12/2011 10/01/2012 11/07/2012 28/08/2012 19/05/2013 09/09/2013 02/04/2015 10/06/2015


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Something about the 13-story Temple Bar Building, at 44 Court Street (and Joralemon) in Brooklyn Heights, caught our eye yesterday. Not the scaffolding, and not the fact that the Joseph P. Day Realty Corp. was offering multiple units in the 1901 building, known as "Brooklyn's first skyscraper."
What caught our eye was the unusual grammar on the Joseph P. Day sign running around the building: "Will Built To Suit." This was repeated several times around the building.
This appears to be a grammar malfunction to us here at McBrooklyn. A survey of Google, however, finds more than 1000 uses of this same phrase. Where the heck did this come from?
The correct usage, "Will Build To Suit," was cited by Google more than 73,000 times.
A post in Education Week asking "Why can't kids spell today?" blames this exact phrase as being partially responsible for today's creeping illiteracy.
Photos by MK Metz
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Monday, February 2, 2009
Brooklyn's Temple Bar Building 'Will Built To Suit'?
4 comments:
- BestViewInBrooklyn said...
Maybe it's the same idea as the "all your base are belong to us" phenomenon?
- February 2, 2009 at 9:09 AM
- Philip said...
I had three boys. All went through NYC gifted public school programs and none of them can spell worth a damn. When I used to bring this up at school meetings with their teachers I was laughed at. And they finished kolledge too. . . I guess there's spell check these days. . .
- February 2, 2009 at 9:50 AM
- bklyngti said...
maybe someone named Will already built the space to suit someone. thank you, i'm here all week.
- February 2, 2009 at 10:57 PM
- mcbrooklyn said...
Ha ha, good one, bklyngti
- February 3, 2009 at 8:31 PM
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You don't have to be Scottish! Any special occasion, whether private, corporate or public, is enhanced by the presence of an expert piper in full regalia. It is well known that Highland bagpipes are loud, but they sound well in large interior spaces such as churches, concert halls and meeting rooms. David Waterhouse is available as a soloist for weddings, anniversaries and other parties, banquets...
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THAT'LL MAKE THE BUILDERS IN ATHENS PULL THEIR FINGERS OUT: Oh, God - have you seen the tracklisting for the Olympic Album? Oh god, it makes you wish they'd just got the discuss throwers together to bellow out a cover of That's Living Alright and had done with. It's called Unity, and it's going to be followed by Harmony (the classical one) and Phos (the Greek one). But let's just focus on Unity:
1, Avril Lavigne 'Knocking On Heavens Door'
2, Destiny's Child - Will I Am 'I Know'
3, Timbaland - Utada - Kiley Dean 'By Your Side'
4, Tiziano Ferro - Jamelia 'Universal Prayer'
5, Sting - Mariza 'A Thousand Years'
6, Beres Hammond - Les Nubians 'Going All The Way'
7, Mr G 'Issues'
8, Earth Wind & Fire - Roots Manuva 'Love Together'
9, Wayne Wonder - Neneh Cherry 'Eyes On the Prize'
10, Lenny Kravitz - Kadim Al Sahir 'We Want Peace'
11, Macy Gray - Keziah Jones 'Oh Yeah'
12, Moby - Public Enemy 'MKLFKWR'
13, Alice Cooper - Xzibit 'Stand'
14, Grönemeyer - Cheb Mami - Dalaras 'Everlasting'
15, Brian Eno - Skin - Rachid Taha 'Still Standing'
16, Trevor Horn - Yiannis - Tarkan - Katia 'Pass The Flame'
You'll notice that most of the tracks are bringing together acts who've never worked together before. Now, it seems to us there's a good reason why, say, Alice Cooper and Xibit or Moby and Public Enemy haven't felt the need to work together before: it's a rubbish idea. Even more interesting is that Avril clearly was like the wheezy boy when choosing teams for basketball - nobody wanted to play with her. We wonder if the spectacularly inappropriate Knockin' On Heaven's Door cover was her idea, or if there's someone quite that stupid elsewhere on the projects.
Friday, May 28, 2004
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The Sea Gull Lighting Brentwood one light outdoor pendant fixture in black is an ENERGY STAR® qualified lighting fixture that uses fluorescent bulbs to save you both time and money. The traditional design accents and pleasant proportions of the Brentwood outdoor lighting collection from Sea Gull Lighting make it a versatile selection for any home. Offered in either a Black Powdercoat or White Powdercoat finish, both with Clear Glass, the ideal aesthetic is achieved with the selection of clear bulbs. The assortment offered in both finishes includes a small one-light outdoor wall lantern, a medium one-uplight outdoor wall lantern, a medium one-downlight outdoor wall lantern, a large one-light wall lantern, a one-light outdoor pendant and a one-light outdoor post lantern. In the Black Powdercoat finish only, a two-light outdoor ceiling flush mount is also available. Most of these fixtures easily convert to LED by purchasing LED replacement lamps sold separately.
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Ciclosporin Versus Alitretinoin for Severe Atopic Hand Dermatitis. (TocyDD)
This study has been terminated.
(delayed start of the trial, both treatment options already have market authorizations, study medication expired)
Technische Universität Dresden
Information provided by (Responsible Party):
Technische Universität Dresden
ClinicalTrials.gov Identifier:
First received: October 29, 2010
Last updated: June 2, 2014
Last verified: June 2014
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The purpose of this study is to investigate the comparative efficacy, safety and efficiency of ciclosporin microemulsion and alitretinoin in adults with severe atopic hand dermatitis.
Condition | Intervention | Phase |
Atopic Dermatitis |
Drug: Ciclosporin Drug: Alitretinoin |
Phase 4 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Investigator) Primary Purpose: Treatment |
Official Title: | Ciclosporin Versus Alitretinoin for Severe Atopic Hand Dermatitis. A Randomized Controlled Investigator-initiated Double-blind Trial. |
Resource links provided by NLM:
Further study details as provided by Technische Universität Dresden:
Primary Outcome Measures:
- Proportion of patients with complete or almost complete clearance according to the Investigator Global Assessment (IGA) within 24-week active therapy in both groups.
Secondary Outcome Measures:
- Time to complete or almost complete clearance according to IGA in both groups
- Proportion of patients with complete or almost complete clearance according to the Patients Global Assessment (PGA) within 12 weeks and 24 weeks of active therapy
- Mean relative change in objective disease severity (HECSI) between baseline and week 4, 8, 12, 16, 20, 24 in both groups
- Mean relative change in quality of life (Skindex 17) between baseline and week 24 in both groups
- Cost-effectiveness of the studied treatment options (cost / QALY gained; assessed by means of the (EQ-5D)
- Mean relative change in work productivity (assessed by means of the work limitations questionnaire (WLQ) in both groups
- Mean utilization of topical steroids within the follow-up period in both groups
- Patient satisfaction with treatment in both groups (assessed using a 100mm VAS Scale)
- Proportion of patients with relapse (≥ 75% of baseline HECSI) within 24-week follow-up after previous complete/almost complete clearance
- In patients with atopic dermatitis on the body: measured percentage of patients with at least 50% improvement in disease severity with the active therapy using the SCORAD.
- Tolerability and safety in both study groups
Enrollment: | 15 |
Study Start Date: | November 2010 |
Study Completion Date: | March 2013 |
Primary Completion Date: | March 2012 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Active Comparator: Ciclosporingroup |
Drug: Ciclosporin
In accordance with the current guideline concerning the use of ciclosporin in dermatology and the current guideline management of hand eczema the daily oral dosage of ciclosporin microemulsion is 2.7 to 4.0 mg/kg bodyweight (half of the total daily dosage will be administered in the morning and in the evening). To enable both body-weight adjusted treatment and double-blind treatment patients will be allocated to 2 different dosages depending on their body weight (50-74.9 kg: daily dosage 200 mg; 75-100 kg: daily dosage 300 mg).
Other Name: Immunosporin
Active Comparator: Alitretinoingroup |
Drug: Alitretinoin
In accordance with the current guideline management of hand eczema alitretinoin will be administered orally in a constant daily dosage of 30 mg.
Other Name: Toctino
Ages Eligible for Study: | 18 Years to 75 Years (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Male and female Patients age > 18 years and ≤ 75 years
- Body weight 50 to 100 kg
- Chronic hand dermatitis (duration > 6 months)
Atopic constitution according to
- Erlanger Atopiescore1 and/or
- positive personal history for atopic eczema, allergic rhinitis, allergic asthma and/or
- elevated serum IgE
- Severe hand dermatitis not responding to treatment with potent topical steroids for at least 4 weeks within the past 6 months due to IGA
- Written informed consent
Exclusion Criteria:
- Participation in other clinical trial within past 4 weeks
- Pregnancy/breastfeeding
- Women within reproductive age except those women who fulfil at least one of the following criteria throughout the total study and until at least 5 weeks after active study treatment in case of early study termination:
- post-menopausal women (12 months physiological amenorrhoea or 6 months amenorrhoea with serum FSH level > 40 mlU/ml),
- postoperative (6 weeks after bilateral ovariectomy with or without hysterectomy)
- Regular and proper use of at least two methods of contraception, including at least one method of contraception with a failure rate <1% per year (eg, implants, depot preparations, oral contraceptives, IUD).
- vasectomy of the partner.
- Women within reproductive age, who do not meet all of the following criteria throughout the whole study or - in case of early study termination - up to 5 weeks after active therapy:
- The patient understands the teratogenic risk associated with taking the study medication.
- The patient understands the need for strict monthly monitoring, the need for a reliable, continuous contraception and the need for regular pregnancy tests throughout the study and - in case of early study termination - up to 5 weeks of active therapy.
- The patient is able to adequately and reliably apply methods of contraception.
- The patient is informed about the possible consequences of pregnancy and knows that she must immediately contact her physician in case of suspected pregnancy.
- The patient gives informed consent about knowing the potential risks and necessary measures to avoid pregnancy.
- Blood and/or plasma donation during the whole study period. In case of early study termination blood and plasma donation is not allowed until 1 month after the end of active study treatment
- UV-therapy within past 3 months
- Concurrent photo-and / or photochemotherapy
- Known Hypersensitivity / Intolerance against ciclosporin, alitretinoin or any other ingredients of Immunosporin® or Toctino®
- Known Allergy against peanuts or soya
- Known Hereditary fructose intolerance
- Acute and/or uncontrolled chronic infectious disease
- Known Congenital or acquired immune deficiency
- Malignant tumor (past or present)
- Uncontrolled arterial hypertension (RR systolic ≥ 160 mm Hg and/or RR diastolic≥ 90 mm Hg despite anti-hypertensive treatment)
- Renal insufficiency (Serum creatinine above normal range)
- Liver insufficiency (CHILD ≥ Stadium B)
- Not sufficiently controlled hyperlipidemia (LDL/HDL ratio > 4 despite medical treatment)
- Clinically significant thyroid hypofunction
- Known Hypervitaminosis A
- Concurrent supplementation of vitamin A or treatment with other retinoids
- Concurrent tetracycline therapy
- Concurrent therapy with St. John's wort ("Johanniskraut")
- Known genetic diseases causing increased UV light sensitivity such as Xeroderma pigmentosum, Cockayne-syndrome, Bloom syndrome
- Known Drug- and/or alcohol abuse
- Known significant psychiatric morbidity
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01231854
Please refer to this study by its ClinicalTrials.gov identifier: NCT01231854
Germany | |
Universitätsklinikum Carl Gustav Carus an der TU Dresden | |
Dresden, Sachsen, Germany, 01307 |
Sponsors and Collaborators
Technische Universität Dresden
More Information
Keywords provided by Technische Universität Dresden:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 24, 2017
Responsible Party: | Technische Universität Dresden |
ClinicalTrials.gov Identifier: | NCT01231854 History of Changes |
Other Study ID Numbers: |
TUD-TOCYDD-044 2009-017520-88 ( EudraCT Number ) |
Study First Received: | October 29, 2010 |
Last Updated: | June 2, 2014 |
Keywords provided by Technische Universität Dresden:
atopic hand dermatitis Chronic hand dermatitis |
Additional relevant MeSH terms:
Dermatitis Dermatitis, Atopic Eczema Skin Diseases Skin Diseases, Genetic Genetic Diseases, Inborn Skin Diseases, Eczematous Hypersensitivity, Immediate Hypersensitivity Immune System Diseases Cyclosporins Cyclosporine Tretinoin |
Alitretinoin Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Immunosuppressive Agents Immunologic Factors Physiological Effects of Drugs Antifungal Agents Anti-Infective Agents Dermatologic Agents Antirheumatic Agents Calcineurin Inhibitors Antineoplastic Agents Keratolytic Agents |
ClinicalTrials.gov processed this record on March 24, 2017


text:
(4 quotes found)
"We're not just sending out the rosaries. We're sending a message in each one of the beads."
Gloria Woodruff
"We don't charge for these. These are mission rosaries."
"We're just carrying on where she left off."
"We can't count (the number made). I never thought to count them."


text:
Puppy vs. Orange (VIDEO)
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I am a SUCKER for dogs. My fiance and I have 3 of them, and we are constantly getting a good laugh at what they do. This video is of a puppy trying to catch and figure out an orange – and it's pretty cute. A great distraction for your Monday at work