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Prayer comes first on Christmas Day
Of all the annual traditions to make the season bright, prayer is the one that sticks out for this young adult.
By Guest Blogger Angelica N. Quinonez
The Christmas season is my favorite time of year. Thanksgiving Day at my grandmother's house—with the first sounds of Christmas can be heard blasting from her living room stereo—marks the beginning of the season in my family. Hearing White Christmas play, even in a city where it never snows, is a reminder that our season of preparation and celebration has begun.
At home on Thanksgiving night, my parents and I discuss the year's Christmas decorations. How will the door and the windows be decorated? What will the Christmas tree-theme be? Will there be a tree-theme? Somewhere between the first Sunday of Advent and Christmas, usually around the Feast of Our Lady of Guadalupe, we setup and decorate our Christmas tree and setup our Nativity set. Our celebration of Advent is fairly traditional.
On Christmas Eve, my entire family gathers together to celebrate Christmas, exchange gifts, and sing Christmas carols at the top of our lungs. Our rendition of "The Twelve Days of Christmas," I believe, can be heard at least a mile or two away, especially our explosive interpretation of the "five golden rings" lyric. It's loud, it's off-key, but it's tradition!
There is one tradition, however, that I've gained a greater appreciation for in my adulthood. At the stroke of midnight on Christmas, we don't open presents and we don't immediately say "Merry Christmas" to each other. Instead, we kneel before the Christ child and we pray.
We pray in celebration of Christ's incarnation so long ago. We pray in thanksgiving for Mary and Joseph's "yes" and faithfulness. We pray for peace in the world and in the lives of our friends and families. We pray in thanksgiving for the graces received throughout the year. And we ask Christ to be re-born in our hearts so that we may live out the spirit and joy of Christmas in our lives each day—that we may be bearers of God's love and light in all we do.
As a little girl, all I wanted to do was rush through the prayers and open my presents. Now that I'm older, I appreciate the true meaning of Christmas beyond the carols and presents.
More than 2,000 years ago true love came in the form of an innocent child, and it was that same love that redeemed us on a cross and calls us in unity, peace, and love today. Remembering that is knowing what "Merry Christmas" truly means.
Guest blogger Angelica holds a Bachelor of Arts in English from Santa Clara University and a Master of Arts in Theology from the University of San Francisco. She is a 28-year-old San Franciscan and aspiring writer. She blogs at Through A Glass Onion.
Read more blogs about Advent and Christmas traditions at uscatholic.org/advent. Submit a guest blog to firstname.lastname@example.com. We may put this together into a holiday theme Meditation Room for the magazine next year. Any reflections selected for publication will win $50!
Guest blog posts express the views of the author. They do not necessarily reflect the views of U.S. Catholic, its editors, or the Claretians.


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to the website of KB Fishing Ireland
us for the shore angling experience of a lifetime....
KB Fishing Ireland is a Family Run Business situated in
Waterville on the beautiful Ring of Kerry. Kevin and his
two very enthusiastic sons Gareth and Sion are the main
Guides and Kevin's Wife Christine is your Hostess.
How many times have fishing
not lived up to your expectations? Join Kevin Brain for a lifetime experience in the follwoing

subset: commoncrawl


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Our mission is to build community through the power of art and education.
Light Bringer Project is a nonprofit, Pasadena-based arts organization founded in 1990 by residents who were exploring the historic contributions that artists, architects and craftsmen made to the local environment. Inspired by these achievements, its founders imagined ways to bring more of today's artists and their creative resources into the mainstream of community life. Today, the organization is widely known for its arts and educational programs provided to underserved youth in the greater Pasadena and Los Angeles area.
In keeping with our mission to build community through the power of the arts and education, Light Bringer Project has delivered a range of unique cultural arts programs and special events that utilize high-degrees of collaboration, volunteerism and community-wide support. For its arts and learning efforts, the organization has received the League of California Cities' Helen Putnam Award of Excellence in Public-Private Partnership. As an arts community participant, the organization was given the Gold Crown Award from the Pasadena Arts Council and has received an award of Outstanding Service from the City of Pasadena Arts Commission.
Community Advocacy
Light Bringer Project has a policy of volunteering and supporting organizations (arts and non-arts related) and serving various sectors of the community. Many of us sit on boards of directors and committees, contributing our energies and expertise. Tom Coston served as one of the founding board members of Leadership Pasadena, and helped steer the organization in its early years. Patricia Hurley then continued Light Bringer's participation on the board, and as a coordinator for the annual Arts & Culture session. Light Bringer also partners with other community organizations like Villa Esperanza Services, helping individuals with special needs, and Day One, partnering on ArtNight Pasadena and other youth-empowering events.
You Shop. Amazon Gives.
AmazonSmile has donated over $100 million to charities thanks to customers shopping at smile.amazon.com. AmazonSmile is a simple and automatic way for you to support Light Bringer Project every time you shop, at no cost to you. You'll find the exact same low prices, vast selection and convenient shopping experience as Amazon.com, with the added bonus that Amazon will donate a portion of the purchase price to your favorite charitable organization. You can also add smilematic to your chrome browser, to be reminded for future shopping.


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I have been scrounging for articles/info about the architecture at Facebook, the challenges & ways they tackle them. What they use & why they use. How do they scale & what are the design decisions for what they do etc. Main underpinning being to learn. Knowing about sites which handles such massive traffic gives lots of pointers for architects etc. to keep in mind certain stuff while designing new sites. I am sharing what I found.
- Facebook Science & Social Graph (Video)
- Scale at Facebook
- Facebook Chat Architecture
- Facebook Blog
- Facebook Cassandra Architecture and Design
- Facebook Engineering Notes
- Quora - Facebook Architecture
- Facebook for 600M users
- Hadoop & its usage at Facebook
- Erlang at Facebook: Chat Architecture
- Facebook Performance Caching
- Facebook Connect Architecture
I have 2 more links but unable to post due to restrictions at this site. Also, please share if anyone has anything better (need not be related to Facebook only).
P.S. - I wasn't able to find good places to share this research, hence this initiative. Hope this helps someone.


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the team is hard at work trying to fix it.. we should be up to date here soon… Copy and paste into your browser..
Thanks for working with us..
the team is hard at work trying to fix it.. we should be up to date here soon… Copy and paste into your browser..
Thanks for working with us..
By JEREMY ELLIOTT (Patriot News) No matter how big the media outlet – ESPN, USA Today or CNN – it can't take away the one common characteristic of a Sprint Car fan: passion. If anything, it enhances it. When the sport is put in a bad light on a national stage, the numbers on the cars or men in the seat no longer matter. This clan rallies around the sport as a whole and flips the middle finger to the rest of the world. That's one of many things that makes Sprint Car racing great. But it's also one of…More
INDIANAPOLIS – Dec. 11, 2014 – The Super DIRTcar Series announced today at the Performance Racing Industry tradeshow a combination of traditional events and races at new venues will make up its 2015 schedule. The 29-race series kicks off during the DIRTcar Nationals presented by Summit Racing Equipment Feb. 18-21 at Volusia Speedway Park in Barberville, Fla. The series championship begins April 25 with a 100-lapper at Fulton (N.Y.) Speedway before an exciting Wednesday night return on May 20 to Canandaigua (N.Y.) Speedway followed on Wednesday, May 27, to Brockville Ontario Speedway. A four-race slate of events in June begins…More
BARBERVILLE, Fla. – Feb. 13, 2015 – Daryn Pittman took the World of Outlaws Sprint Car Series season opener Friday night with an epic last lap pass of the reigning series champion Donny Schatz. Just a lap sooner the feature win was in Schatz's sights as he approached the lapped car of Kraig Kinser. Schatz dove low in turns three and four to make the pass but was not able to make the line stick. As he exited the turn his Bad Boy Buggies car drifted up the track and over the cushion. Pittman saw his opportunity. "When I saw…More
By JOSHUA JOINER OCALA, Fla. – Feb. 13, 2015 – Turning around his sluggish start to the season, Darrell Lanigan of Union, Ky., topped a late duel with Josh Richards of Shinnston, W.Va., during Friday's DIRTcar UMP-sanctioned A-Main at Bubba Raceway Park to earn a $5,000 victory during the opening night of the fourth annual Bubba Army Winter Nationals. Lanigan, the three-time and defending World of Outlaws Late Model Series champion, rallied after losing the lead to Richards on lap 20 of the 30-lapper and retook command when Richards struggled with traffic on lap 26. The 44-year-old Lanigan pulled away…More
GIBSONTON, FL – "We just missed the set-up in that first race tonight; we had just enough time to make some adjustments for this race. We won that first heat so that put us on the pole. The car was really good. I had a little bit of a push getting into turn two, but otherwise, the car was not a handful like the previous nights. I was hoping maybe Jr. could get up there so we could take first and second." "I have so many people to thank; Messilla Valley Transportation, Henderson Motorsports, Watters Auto Land, Clements Engines, Longhorn Chassis,…More
CONCORD, N.C. – Feb. 4, 2015 – DIRTcar 358-Modified racers will have more incentive than ever to race not only their home tracks this season, but also the series in the fall. In addition to the traditional post Labor Day series events, drivers will earn points during the season from the new Super Series Starter (SSS) Events at their weekly tracks. The 2015 358-Modified Series Championship combines Home Track Points, plus "SSS" points, plus points from the Fall Series events to equal the Championship. The weekly track Mr. DIRTcar program similar to last year's runs from now until Sept. 6…More
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Queen of Tsawwassen
Event Info
July 13th, from 8:00pm
Inventory Vancouver
45 Powell St.
Vancouver, BC
Over the past year we've worked alongside five photographers and Japanese publisher twelvebooks to produce this publication. Queen of Tsawwassen is a 120-page, full colour book featuring 78 images from Ali Bosworth, Seth Fluker, Jennilee Marigomen, Dan Siney and Chris Taylor. The title is a reference to one of the original BC Ferries which operated between Vancouver Island and the mainland – a unique region of the Pacific Northwest where much of the book's imagery was captured.
We will be hosting a party at our Vancouver store to celebrate the release of the book this Saturday.


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Light, comfortable bag with original design made by ZIB* artist Annija Kakarane. The bag has a zip through fastening, adjustable strap fastening and a plastic belt buckle. The lining of bag is made of syntethic material.
- Size: Width 30cm; Depth 13cm;
- Maximum size of strap 111cm;
- One size only


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How it's Grown
All the lamps are GROWN, not manufactured, from mushrooms. Through a partnership with Ecovative, we are able to grow lamp shades using their extensive mushroom mycelium research, tested technology and patented growing process. The growth process uses agricultural byproducts, such as seed husks and corn stalks, and combines them with liquid mushroom mycelium. The mycelium then binds with these components and grows for several days in custom molds. When the growth process is complete, the material is heated and dried, ending the growth cycle. At the end of its life, the mushroom material can be broken into smaller pieces, then added to your backyard compost to fully biodegrade!


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Thomas Mueller under fire over reaction as Pepe sees red for head-butt
Portugal defender Pepe faces a three-match ban for head-butting Thomas Mueller, but the German striker has also come under fire over his theatrical reaction.
Real Madrid's Pepe, not amused by what he felt was a case of cheesy acting, went over to Mueller as he sat on the turf, bent down with his head close to Mueller's and, with a short, almost imperceptible burst, head-butted the German.
The Brazil-born centre back had caught Mueller in the face in an innocuous-looking challenge but took umbrage as Mueller went down, returning to the forward and thrusting his forehead against the German's.
Serbian referee Milorad Mazic had no hesitation in dismissing Pepe in the 37th minute.
A red card brings a mandatory one-game ban at the World Cup but that is usually extended in the case of a sending-off for violent play.
Portugal coach Paulo Bento suggested the referee was biased in favour of Germany after his side had a penalty awarded against them and had Pepe sent off.
"These were the two things that seemed to show bias and they were both decisive," he told a news conference.
"The penalty was forced," added Bento, seemingly suggesting that Mueller, who was sitting on the turf when an incensed Pepe came back to accost him, was guilty of instigating the situation that had the Portugal defender red carded by Milorad Mazic of Serbia.
"I don't know if he was sent off because of his reputation," said the coach.
Mueller said he felt Pepe's fist strike his head as both players tried to head a ball and he went crashing to the ground.
Mueller jumped on his feet and the two shouted at each other for a tense moment before being separated. Pepe was sent off.
"I'd like to see it in TV," Mueller said. "I only hope that I looked okay. I felt a blow from his fist. But what happened after that I can't really remember, whether we were head-to-head or not. I just hope it didn't look stupid on TV.
"I didn't want to cheat," Mueller added. "I don't know for sure how I got out of there."
Mueller, who won the Golden Boot of the 2010 World Cup with five goals in six appearances, said he had not been looking for a clash with Pepe but was not about to back down against the defender either.
"I've experienced a number of things in international football matches over the last four years and I'm not the kind of guy who gets easily scared," said the 24-year-old Mueller.
Twitter uses were quick to add their thoughts on the incident.
Pepe's latest episode of violent conduct follows a series of similar incidents in recent years playing for his club Real Madrid, including one in a La Liga match against Getafe in April 2009 which earned him a 10-game ban.
With the scores level at 2-2 and three minutes left in the clash at the Bernabeu, Pepe pushed Getafe's Francisco Casquero and the referee awarded a penalty.
Pepe then kicked Casquero on the ground and a second swipe saw him rake his studs over the midfielder's back. In the ensuing melee he struck another Getafe player, Juan Albin, in the face.
He was shown a straight red card, having already picked up a yellow earlier in the match.
He was red-carded in a bad-tempered Champions League semi-final against Barcelona in 2011 for a studs-up lunge on Barca full back Dani Alves and earned wide condemnation for stamping on Lionel Messi's hand in another Real-Barca game in 2012.


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SuperFlow's Axiline and Hicklin transmission test stands cover the complete range of light-duty, medium-duty, heavy-duty and cross drive transmissions on the market today. With solutions for everything from passenger cars to the M1 tank and features like mechatronic shift controls, no-hassle precision aligment tooling and the available WinDyn Data Acquisition and Control system for fully automated tests and reports, SuperFlow transmission dynos are the only choice of the top transmission remanufacturers world wide. Check out or custom testing solutions page for examples of custom transmission test stands we've built for heavy duty cross drive dynos and full AC regenrative test stands.
The Axiline 97000 is the perfect transmission dynamometer for most light to medium-duty front wheel drive, rear wheel drive, transverse, manual and CVT transmissions.
The Hicklin EDECT heavy-duty transmission dynamometer is designed to handle the toughest inline, v-drive and angle drive transmissions. The EDECT is also available in custom configurations to meet your needs.
Hicklin Engineering has designed and built custom cross-drive transmission dynamometers for militaries, OEMs, and remanufacturers to test transmissions like the X-1100 and HMPT-500.
The Axiline 84000 manual shift transmission dynamometer tests both light and heavy-duty manual transmissions including Fuller, Meritor, Rockwell, Spicer, ZF and others.
Website design and development by Spindustry Digital, Des Moines, Iowa


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Health Hotlines App
NLM's Health Hotlines is now available as an app for the iPhone and iPod Touch (http://itunes.apple.com/app/health-hotlines/id376404746?mt=8). Health Hotlines is also compatible with the iPad.
Health Hotlines is a compilation of organizations with toll-free telephone numbers to assist the public in locating health-related information. It is derived from DIRLINE, NLM's Directory of Information Resources Online, which contains descriptions of almost 9,000 health and biomedical organizations and resources. Some of the subject areas included in Health Hotlines are AIDS, cancer, diseases and disorders, maternal and child health, aging, substance abuse, disabilities and mental health.
Health Hotlines is also available on the NLM's Web site http://healthhotlines.nlm.nih.gov.
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AO Forum ::
Atlantian Oceania
Regional Discussion
Regional Map 5.1
May 31 2018, 06:17 AM
The current AO Map and its Change History can be found in the
Official AO Map Factbook
How to get on the Regional Map?
First, you must meet the following criteria:
Nations will not be added to the map until they have been in the region for 28+ days. You can still request beforehand, however.
You must have a unique flag, that doesn't belong to any other nation within the region, or a nation that exists in real life. (Historical flags and flags of national subdivisions are fine, however.)
You must have some national information available (be it in the form of a factbook on the main site, or a post within the forums).
Then, you simply fill out your application, which must contain the following things:
Your nation name.
The plot of land you'd like. If you're proficient in any image editor, feel free to download the map, cut out the bit you want, colour it in, and post it back! Otherwise, a simple description will do.
A link to that national information I mentioned earlier.
Your capital city, or a major one, so I can put that on the map too.
Some Considerations:
Don't make a massive claim. Sure, a fluid scale is used on this map, but don't take the biscuit. If you go RP-ing your nation is the size of Russia when it's the size of Nellietopia on the map, then I won't be too impressed.
Nations that are puppets of other users must declare themselves as such, and also actively RP the claim of the puppet nation (and provide a link to said RP in their application).
Don't try and grab land around other nations in order to cut them off from the rest of the world - these will be rejected unless coordinated and approved by that nation
All claims are subject to approval - the Atlantian Oceania Cartographic Institute is a fickle mistress, and claims that are deemed terrible or improperly submitted will not be accepted. Feel free to try again, however.
If you don't like any of the lovely plots of land available, then land can be created, however this will be reviewed with an even stricter eye than any other claim. The preference is always going to be to use existing land - even if it need be 're-shaped' - opposed to just dropping an entire new Island somewhere.
Seriously, we've got a lot of nice mainland - why not take some of that?
Please include the word "Abracadabra" in your application
, as we all know that you don't get anything you want without saying the magic word. Also, it shows you've at least read this far. Although, please do read on.
We can add things like lakes, if they're particularly important, however they cannot be placed where other features had been RP'ed before - like the Great Calanian Desert, for example.
Nations that have CTE'd will remain on the map for a timeperiod after their extinction as deemed appropriate by the AOCI, and if they have made a significant contribution to the region or to the greater forum (as is the case with choice nations included on the map), this will be extended further (or indefinitely).
And that seems to be about it! Any more questions? Reply or use the TG system. Posted in the last map thread, but your claim hasn't been processed? Post a new one here, meeting all the criteria! Happy mapping!
Posts: 1208
Jun 1 2018, 08:23 PM
Commonwealth of Baker Park
Some info (there's plenty more in the other factbooks):
capital city Belle Haven (I put the other cities on there for my own reference, you don't need to put any of them on)
Posts: 5
Oct 31 2018, 12:59 AM
(BakerPark @ Jun 1 2018, 08:23 PM)
Commonwealth of Baker Park
Some info (there's plenty more in the other factbooks):
capital city Belle Haven (I put the other cities on there for my own reference, you don't need to put any of them on)
re-posting b/c the image link went dead
Posts: 5
Mar 25 2019, 03:47 PM
My countries factbook is here:
And my claim is everything unclaimed to the left of the line drawn on this:
One Post Wonder
Posts: 1
Mar 26 2019, 05:25 PM
The Republic of Flavovespia would like to claim the island located South of Osarius, or an island with the same shape if that is possible. Our factbook can be found below, with a map of the nation including the capital.
Flavovespia Factbook
One Post Wonder
Posts: 1
Mar 27 2019, 10:00 PM
How about a nice archipelago?
After some very in-depth thinking and a bit of research, I would like to formerly make a claim on the AO Map, seeing as how I have been in the region for a couple of months.
Also, if possible, could I get a higher resolution map of my claims, so that I may begin drawing up all those wonderful nation maps; provinces, military commands, cities, sports team influences... Yes, all those wonderful things.
Obviously, the
is going to be out of date, at least until I can write up a newish history, add a recent map, and work out the population numbers and land areas of the claim.
The Avatarian Republics of Gyatso-kai will live on!
One Post Wonder
Posts: 1
Apr 25 2019, 07:16 AM
Hai. It's me Dritten Asopie. Since I am here for Luke 35 days I think it is okay for me to have a place in the map. So what I wanna pick is anything. I'm on mobile so I can't really see what nations are there, nonetheless I am okay with anything.
Above is my factbook.
My capital city is Hallesht and please add Kantex of Fascgend(your choice) BAI.
Dritten Asopie
One Post Wonder
Posts: 1
May 9 2019, 03:54 PM
It's not very important, but could my capital be changed on the next version of the map? The location is the same, but instead of Ko-oren City, could it be named something like '4 capitals'?
ICly there are four cities that share capital city duties: Mayara, Gehrenna, Maethoru, and Senoren, listed in order of importance. Mayara has most, Senoren has least functions.
Scribe in Training
Posts: 28
May 17 2019, 02:17 AM
(BakerPark @ Oct 31 2018, 12:59 AM)
(BakerPark @ Jun 1 2018, 08:23 PM)
Commonwealth of Baker Park
Some info (there's plenty more in the other factbooks):
capital city Belle Haven (I put the other cities on there for my own reference, you don't need to put any of them on)
re-posting b/c the image link went dead
Posts: 5
Jun 5 2019, 10:15 PM
Scandonia (Pacitalia puppet) reactivated today.
I am reclaiming Scandonia's previous land area per:
The best place on earth.
Posts: 504
Jun 6 2019, 06:55 AM
Nation name: Lochario (The Authoritarian Republic of Lochario)
Plot of land : in the middle of the map (about the same size as Valanora)
Link to the info:
Capital city: Zun
This post has been edited by
on Jun 6 2019, 07:17 AM
One Post Wonder
Posts: 1
Oct 6 2019, 04:02 PM
Nation Name: Hapilopper
Plot of Land: The west-central part of Azeruia, bordered by Banija and Demot
Capital City: Hapilopper City
Info: Not a whole lot at the moment. The closest I might get to that might be here:
More info will come once I know what I can work with.
This post has been edited by
on Oct 6 2019, 04:08 PM
One Post Wonder
Posts: 1
0 Members:
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The parish of Kelling in Norfolk was home to another branch of the family. [1]CITATION[CLOSE]
Lewis, Samuel, A Topographical Dictionary of England. Institute of Historical Research, 1848, Print.
|Popular Products
|Armorial History With Coat of Arms
|Coat of Arms & Surname History Package
|Family Crest Image (jpg) Heritage Series - 300 DPI
|Coffee Mug
|Armorial History with Frame
|Framed Surname History and Coat of Arms


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Zeocin™ is a member of the bleomycin/phleomycin family of antibiotics isolated from Streptomyces. It shows strong toxicity against bacteria, fungi (including yeast), plants and mammalian cell lines (Calmels et al., 1991; Drocourt et al., 1990; Gatignol et al., 1987; Mulsant et al., 1988; Perez et al., 1989). Since Zeocin™ is active in both bacteria and mammalian cell lines, vectors can be designed that carry only one drug resistance marker for selection.
Zeocin™ is a formulation of phleomycin D1, a basic, watersoluble, copper-chelated glycopeptide isolated from Streptomyces verticillus. The presence of copper gives the solution its blue color. This copper-chelated form is inactive. When the antibiotic enters the cell, the copper cation is reduced from Cu2+ to Cu1+ and removed by sulfhydryl compounds in the cell. Upon removal of the copper, Zeocin™ is activated and will bind DNA and cleave it, causing cell death.
Resistance to Zeocin™
A Zeocin™ resistance protein has been isolated and characterized (Calmels et al., 1991; Drocourt et al., 1990). This 13,665 Da protein, the product of the Sh ble gene (Streptoalloteichus hindustanus bleomycin gene), binds stoichiometrically to Zeocin™ and inhibits its DNA strand cleavage activity. Expression of this protein in eukaryotic and prokaryotic hosts confers resistance to Zeocin™.
Handling Zeocin™
- High ionic strength and acidity or basicity inhibit the activity of Zeocin™. Therefore, we recommend that you reduce the salt in bacterial medium and adjust the pH to 7.5 to keep the drug active (see Low Salt LB Medium).
- Store Zeocin™ at -20°C and thaw on ice before use.
- Zeocin™ is light sensitive. Store the drug and plates or medium containing the drug in the dark.
- Wear gloves, a laboratory coat, and safety glasses when handling Zeocin™ containing solutions.
- Do not ingest or inhale solutions containing the drug.
- Be sure to bandage any cuts on your fingers to avoid exposure to the drug.
Concentrations of Zeocin™ to use for Selection
Zeocin™ and the Sh ble gene can be used for selection in mammalian cells (Drocourt et al., 1990; Mulsant et al., 1988), plants (Perez et al., 1989), yeast (Calmels et al., 1991; Gatignol et al., 1987), and prokaryotes (Drocourt et al., 1990). Suggested concentrations of Zeocin™ to use for selection in mammalian tissue culture cells, yeast, and E. coli are listed below.
|Zeocin™ Concentration and Selective Medium
|E. coli
|25-50 μg/ml in Low Salt LB medium*
|Yeast 50
|50-300 μg/ml in YPD or minimal medium
|Mammalian cells
|50-1000 μg/ml (varies with cell line)
*For efficient selection, the concentration of NaCl should not exceed 5 g/liter.
Use 25-50 μg/ml of Zeocin™ for selection in E. coli. High salt and extremes in pH will inhibit the activity of Zeocin™ (see recommendations below).
E. coli Host
Any E. coli strain that contains the complete Tn5 transposable element (i.e. DH5αF´IQ, SURE, SURE2) encodes the ble (bleomycin) resistance gene. These strains will confer resistance to Zeocin™. For the most efficient selection, use an E. coli strain that does not contain the Tn5 gene (i.e. TOP10, DH5, DH10, etc.).
Ionic Strength and pH
Extremes in pH and high ionic strength will inhibit the activity of Zeocin™. To optimize selection in E. coli, the salt concentration must be < 110 mM and the pH must be 7.5. A recipe for Low Salt LB is provided below to optimize selection in E. coli.
Low Salt LB Medium
10 g Tryptone
5 g NaCl
5 g Yeast Extract
- Combine the dry reagents above and add deionized, distilled water to 950 ml. Adjust pH to 7.5 with 1 N NaOH and bring the volume up to 1 liter. For plates, add 15 g/L agar before autoclaving.
- Autoclave on liquid cycle at 15 psi and 121°C for 20 minutes.
- Thaw Zeocin™ on ice and vortex before removing an aliquot.
- Allow the medium to cool to at least 55°C before adding the Zeocin™ to 25 μg/ml final concentration.
Store plates and unused medium at +4°C in the dark. Plates and medium containing Zeocin™ are stable for 1-2 weeks.
Invitrogen™ imMedia™ is available for fast and easy microwaveable preparation of Low Salt LB medium or agar containing Zeocin™. See below for ordering information. For more information, see our website or call Technical Service.
|Catalog no.
|imMedia™ Zeo Liquid
|20 pouchest
|imMedia™ Zeo Agar
|20 pouchest
t Each pouch provides sufficient reagents to prepare 200 ml of liquid medium or 8-10 standard size agar plates.
We have successfully transformed plasmids conferring Zeocin resistance into Saccharomyces cerevisiae and Pichia pastoris. The concentration of Zeocin™ required to select resistant transformants may range from 50 to 300 μg/ml, depending on the strain, pH, and ionic strength. Guidelines are provided below to assist you with selecting Zeocin™-resistant transformants.
We do not recommend spheroplasting for transformation of yeast with plasmids containing the Zeocin™ resistance marker. Spheroplasting involves removal of the cell wall to allow DNA to enter the cell. Cells must first regenerate the cell wall before they are able to express the Zeocin™ resistance gene. Plating spheroplasts directly onto selective medium containing Zeocin™ will result in complete cell death.
Transformation Method
We recommend electroporation, lithium cation protocols, or our EasyComp™ Kits for transformation of yeast with vectors that encode resistance to Zeocin™. Electroporation yields 103 to 104 transformants per μg of linearized DNA and does not destroy the cell wall of yeast. If you do not have access to an electroporation device, use chemical methods or one of the EasyComp™ Kits listed below.
|Catalog no.
|S. c. EasyComp Transformation Kit (for Saccharomyces cerevisiae)
|6 x 20 transformations
|Pichia EasyComp Transformation Kit (for Pichia pastoris)
|6 x 20 transformations
Ionic Strength and pH
Since yeast vary in their susceptibility to Zeocin™, we recommend that you perform a kill curve to determine the
lowest concentration of Zeocin™ needed to kill the untransformed host strain. In addition, the pH of the selection medium may affect the concentration of Zeocin™ needed to select resistant transformants. We recommend that you test media adjusted to different pH values (6.5 to 8) for the one that allows you to use the lowest possible concentration of Zeocin™.
Selection in Yeast
For successful selection of Zeocin™-resistant transformants we recommend the following:
- After transformation (either by electroporation or chemical transformation), allow the cells to recover for one hour in YPD medium.
- For electroporated cells, plate your transformants on YPD containing 1 M sorbitol. Sorbitol allows better recovery of the cells after electroporation.
- For chemically transformed cells, plate cells on YPD or minimal plates.
- Plate several different volumes (i.e. 10, 25, 50, 100, and 200 μl) of the transformation reaction. Plating at low cell densities favors efficient Zeocin™ selection.
Mammalian cells exhibit a wide range of susceptibility to Zeocin™. Concentrations of Zeocin™ used to select stable cell lines may range from 50 to 1000 μg/ml, with the average being around 250 to 400 μg/ml. Factors that affect selection include ionic strength, cell line, cell density, and growth rate. Review the guidelines below to ensure successful selection of stable cell lines.
Zeocin™ mechanism of killing is quite different from neomycin and hygromycin. Cells do not round up and detach from the plate. Sensitive cells may exhibit the following morphological changes upon exposure to Zeocin™:
- Vast increase in size (similar to the effects of cytomegalovirus infecting permissive cells)
- Abnormal cell shape, including the appearance of long appendages
- Presence of large empty vesicles in the cytoplasm (breakdown of the endoplasmic reticulum and Golgi apparatus or scaffolding proteins)
- Breakdown of plasma and nuclear membrane (appearance of many holes in these membranes)
Eventually, these cells will completely break down and only cellular debris will remain.
Zeocin™-resistant cells should continue to divide at regular intervals to form distinct colonies. There should not be any distinct morphological changes in Zeocin™-resistant cells when compared to cells not under selection with Zeocin™.
For selection in mammalian cells, physiological ionic strength and pH are much more important for cell growth, so more Zeocin™ may be needed for selection relative to yeast or bacteria.
Selection in Mammalian Cell Lines
To generate a stable cell line that expresses your protein from an expression construct, you need to determine the minimum concentration required to kill your untransfected host cell line (see Determination of Zeocin™ Sensitivity, below). In general, it takes 2-6 weeks to generate foci with Zeocin™, depending on the cell line. Because individual cells can express protein at varying levels, it is important to isolate several foci to expand into stable cell lines.
Determining Zeocin™ Sensitivity
Determine the minimal concentration of Zeocin™ required to kill the untransfected parental cell line using the protocol below.
- Plate or split a confluent plate so the cells will be approximately 25% confluent. Prepare a set of 8 plates. Grow cells for 24 hours.
- Remove medium and then add medium with varying concentrations of Zeocin™ (0, 50, 100, 200, 400, 600, 800, and 1000 μg/ml) to each plate.
- Replenish the selective medium every 3-4 days and observe the percentage of surviving cells over time. Select the concentration that kills the majority of the cells in the desired number of days (within 1-2 weeks).
If you have trouble distinguishing viable cells by observation, we recommend counting the number of viable cells by trypan blue exclusion to determine the appropriate concentration of Zeocin™ required to prevent growth.
Selection Tip
Some cells may be more resistant to Zeocin™ than others. If cells are rapidly dividing, Zeocin™ may not be effective at low concentrations. We suggest trying the following protocol to overcome this resistance:
- Split cells into medium containing Zeocin™.
- Incubate cells at 37°C for 2-3 hours until the cells have attached to the culture dish.
- Remove the plates from the incubator and place the cells at +4°C for 2 hours. Be sure to buffer the medium with HEPES.
- Return the cells to 37°C.
Incubating the cells at +4°C will stop the cell division process for a short time, allow Zeocin™ to act, and result in cel death.
Once you have determined the appropriate Zeocin™ concentration to use for selection, you can generate a stable cell line with your construct.
- Transfect your cell line and plate onto 100 mm culture plates. Include a sample of untransfected cells as a negative control.
- After transfection, wash the cells once with 1X PBS and add fresh medium to the cells.
- Forty-eight to 72 hours after transfection, split the cells using various dilutions into fresh medium containing Zeocin™ at the pre-determined concentration required for your cell line. By using different dilutions, you will have a better chance at identifying and selecting foci.
- Feed the cells with selective medium every 3-4 days until cell foci are identified.
- Pick and transfer colonies to either 96- or 48-well plates. Grow cells to near confluence before expanding to larger wells or plates.
Note: If your cells are more resistant to Zeocin™, you may want to use the selection tip described above. Simply split cells into medium containing Zeocin™, incubate at 37°C for 2-3 hours to let cells attach, then
place the cells at +4°C for 2 hours. Remember to buffer the medium with HEPES.
Maintaining Stable Cell Lines
To maintain stable cell lines, you may:
- Maintain the cells in the same concentration of Zeocin™ you used for selection
- Reduce the concentration of Zeocin™ by half
- Reduce the concentration of Zeocin™ to the concentration that just prevents growth of sensitive cells but does not kill them (refer to your kill curve experiment).
- Berdy, J. (1980) Bleomycin-Type Antibiotics. In Amino Acid and Peptide Antibiotics, J. Berdy, ed. (Boca Raton, FL: CRC Press), pp. 459-497.
- Calmels, T., Parriche, M., Burand, H., and Tiraby, G. (1991). High Efficiency Transformation of Tolypocladium geodes Conidiospores to Phleomycin Resistance. Curr. Genet. 20, 309-314.
- Drocourt, D., Calmels, T. P. G., Reynes, J. P., Baron, M., and Tiraby, G. (1990). Cassettes of the Streptoalloteichus hindustanus ble Gene for Transformation of Lower and Higher Eukaryotes to Phleomycin Resistance. Nucleic Acids Res. 18, 4009.
- Gatignol, A., Baron, M., and Tiraby, G. (1987). Phleomycin Resistance Encoded by the ble Gene from Transposon Tn5 as a Dominant Selectable Marker in Saccharomyces cerevisiae. Molecular and General Genetics 207, 342-348.
- Graham, F. L., Smiley, J., Russell, W. C., and Nairn, R. (1977). Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5. J. Gen. Virol. 36, 59-74.
- Mulsant, P., Tiraby, G., Kallerhoff, J., and Perret, J. (1988). Phleomycin Resistance as a Dominant SelectableMarker in CHO Cells. Somat. Cell Mol. Genet. 14, 243- 252.
- Perez, P., Tiraby, G., Kallerhoff, J., and Perret, J. (1989). Phleomycin Resistance as a Dominant Selectable Marker for Plant Cell Transformation. Plant Mol. Biol. 13, 365-373.


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Explore Our Hotel
Welcome to the Holiday Inn Express Hotel in Midtown Memphis, Tennessee
Let us welcome you to Memphis and spoil you with our Southern hospitality while you are lodging at our Midtown Memphis, TN hotel that is located close to I-240 and is just minutes from downtown Memphis. The hotel property is adjacent to Methodist University Hospital and near nine other major medical centers.
Leisure travelers will love our close proximity to downtown Memphis with Beale Street, the Peabody Ducks, Mud Island and Graceland just minutes away. Our Union Street access also means it's just a short drive to the FedEx Forum or AutoZone Park, which are the perfect locations for a family day trip.
Business travelers will appreciate our midtown Memphis hotel's easy access to I-240, I-55 and I-40. Our hotel is just eight miles from Memphis International Airport, and the Amtrak Station is two miles away. Our premium business amenities include a Business Center and free Internet access.
You'll enjoy our Southern charm as much as the free high-speed, wireless Internet access in our inviting rooms. With a fitness center and outdoor pool, you'll feel completely at home. We also offer a special rate for guests with a loved one at Methodist Hospital. Call our hotel in Memphis, Tennessee today, and take advantage of our great hotel deals and rates.
- Black-out Shades
- Pillow Menu
- Crib Available
- Iron/Ironing Board
- Separate Hanging Closet
- In-Room Heating and A/C Controls
- Sofa Bed/Sleeper Couch
Bathroom/Personal Care
- Private Bathroom
- Bathroom Amenities Available
- Hair Dryer
- Bathtub
In-Room Features
- Coffee Maker
- Flat-screen TV
- Work Desk with Lamp
- Free Local Calls
- Cable/Satellite
- Premium Channels
- Two-line Phone
- Phone with Voicemail
- Complimentary Morning Newspaper
Added Value
- Connecting Rooms Available
- Complimentary Coffee/Tea Supplies
- Complimentary Bottled Water
- Full Breakfast Included
- Breakfast Buffet Included
- Continental Breakfast Included
- Complimentary Coffee in Lobby
- Kids Eat Free
- Off-site Restaurant Delivery Available
Business Services
- On-Site Business Center
- Printer
- Copier
- Scanner
- Office supplies available
Internet Access
- Free High-Speed Internet in all Rooms
- Wireless Internet service is free for all IHG® Rewards Club members
Entertainment & Recreation
- Outdoor Pool
- Outdoor Pool Hours of Operation: 10:00 AM - 10:00 PM
- Pool Open from: 01-May-2019 to 03-September-2019
Health & Fitness
Complimentary Fitness Center
2 treadmills, 1 recumbent bike, 1 stationary bike, 1 elipitical machine, 1 weight machine
Fitness Center Type: LIMITED
Fitness Center Equipment:
- Treadmill
- Elliptical Machines
- Stationary Bicycle
Last Renovation of Fitness Center Equipment: 2017
Housekeeping & Laundry
- Daily Housekeeping
Added Value
- Concierge Services
- Wake Up Calls
Hotel Details
1180 Union Avenue
Memphis, Tennessee 38104
United States
Check In: 3:00 PM
Check Out: 11:00 AM
Check-in Age: 18
Parking + -
- Complimentary Self Parking Available
Accessibility + -
- Public Entrance
- Guest Rooms
- Elevators
- Public Restrooms
- Registration Desk
- Exercise Facility
- Business Center
- Pool
- Number of Accessible Meeting Rooms: 1
Accessible Hotel Areas
- Registration Area
- Accessible Guest Rooms
- Business Center
- Exercise Facility
- Pool
Hotel Areas with Accessible Routes from Accessible Public Entrance
- Accessible Self Parking
- Van Accessible Self Parking
- Closed Caption TVs
- Telephone with TDD
- Visual Alarm/Alert in Guest Rooms
- Visual Alarm/Alert in Public Spaces
- Communication Kits with Visual Alarms
Provided by Hotel
Pet Policy + -
- Service Animals Allowed
Facility + -
- Number of Floors: 4
- Total Number of Rooms: 125
- Number of Suites: 0
- Number of Non-Smoking Rooms: 125
- Number of Accessible Rooms: 7
- Connecting Rooms Available
- Complete Hotel Renovation-Lobby, Guest Rooms, Public Spaces, Fitness Room
- Public Spaces Renovated in: 2017
- Guest Rooms Renovated in: 2017
Credit Cards + -
- American Express
- Visa
- MasterCard
- Diners Club
- Carte Blanche
- Discover


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2016 Texas Cowboy Wall Calendar
Stoecklein calendars provide the opportunity to celebrate the spirit of the West every day of the year. The calendars showcase the finest western photography, capturing today's cowboys and cowgirls as they live out the traditions of the American West, with easy-to-read dates and plenty of room for notes. 12" x 12" folded with stapled pages, 12" x 24" open.


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Davidowj necesitaba un nuevo diseño de otro y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 55 diseños de 5 diseñadores freelance.
Thomas D. Davidow & Associates
Thomas D. Davidow & Associates is a family business consulting firm that assists family businesses in any matter, from conflict resolution and succession to executive coaching and establishing governance. For more information you can go to the website: http://www.tdavidow.com/index.html
Family owned businesses have been in the market for centuries and make up almost 80% of the economy. However, a majority of these businesses are unaware of family business consultants and the services they provide. Therefore the target audience is family members within a family owned business, and professionals (i.e. financial advisors, laywers, accountants) who work for a family owned business whose expertise may be limited in helping the family solve certain problems and may want to refer them to a consultant.
We are trying to create a design that represents the business model. Families have issues and business have issues, so when these two entities overlap the problems that arise are unique and the skill sets needed are unique as well. Each associate has a specific skill set that can be used to help address and help specific issues or problems a family owned business may face. They are: 1) Family Dynamics 2) Strategic Planning 3) Governance 4) Conflict Resolution and Legal Mediation.
The concept for this business model design can be described like this:
Two circles within each other. The inner circle, saying "family" and the outer circle with "business" written in it. Then we would like each of the 4 skills mentioned above to be placed in arrows, circles, sqaures or whatever loooks best around the outside of the circle. Please feel free to play around with this concept as much as you want! (i.e. when I say circle, it doesn't have to be a circle!)
It might also be helpful to go to the website to get a feel for the style etc (the logo will be placed on the website). http://www.tdavidow.com/index.html


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Co-founder Mikkel Borg Bjergsø of the Danish brewery Mikkeller travels around the world, brewing beers at other breweries.
If you are like me, when you like a brewery, you want to try as many of its beers as possible.
Danish brewery Mikkeller makes that a little difficult.
Mikkeller is, to put it simply, prolific. Since being founded in 2006, it has brewed more than 200 beers.
Not bad for a brewery that does not have a brewery of its own. It is known as a "gypsy" brewery. Co-founder Mikkel Borg Bjergsø travels around the world, brewing beers at other breweries.
Mikkeller beers run the gamut of styles — they have a couple of lagers, pale ales, IPAs, Belgian-style ales and many India pale ales (IPAs), double IPAs and a huge vareity of stouts.
The amazing thing is how good most of the Mikkeller beers are. Although far from trying them all (they're expensive, from $6 to $30), most of them range from very good to excellent. You would think there would be some stinkers in there, but I haven't run across any yet.
Mikkeller may be best known for its collection of stouts.
Mikkeller brews Beer Geek Breakfast, a 7.5 percent alcohol by volume (ABV) stout brewed with gourmet chocolate. Mikkeller also brews a smoky version of this beer, called Beer Geek Bacon.
Another of the "Beer Geek" beers is the Beer Geek Brunch Weasel, which is a stronger version of the Beer Geek Breakfast, and is also brewed with oatmeal. There is also the Beer Hop Breakfast, which is an extremely hoppy version of the Beer Geek Breakfast.
Mikkeller also experiments with various type of barrels to age its beers, including the Beer Geek beers. Many breweries age beers in bourbon barrels, but Mikkeller uses other barrels such as rum, cognac, tequila, red wine and white wine barrels.
Other popular stouts include the absolutely huge Black. Black is 17.5 percent ABV. It is brewed with champagne yeast. This is a beer, if you buy it, you'd want to let sit for awhile. There's a lot of boozy flavor in this that will mellow with age.
My favorite of the Mikkeller stouts is probably Black Hole. It is a 13.1 percent ABV stout brewed with honey, coffee and vanilla. The booziness is not too overwhelming, and it is surprisingly smooth for such a big beer. It is one of those beers that you will remember drinking it.
Mikkeller also brews many IPAs. They did a series of single-hop IPAs. The base beer is the same, but the only difference is the hops. It's cool to taste a few of these side-by-side to see what individual flavors hops add to a beer.
Another IPA is the I Beat yoU. The name is a play on the beer term, IBU, which stands for international bitterness units, the standard used to measure how bitter a beer is. This 7 percent ABV IPA is brewed with six different hops.
Mikkeller also brews one of the most unique IPAs on the market today, the Koppi Coffee IPA. Most coffee beers are stouts and an occasional porter. The bitter flavors of IPAs wouldn't seem to mix well with real coffee, but somehow, this really worked. I found myself enjoying it more and more as I drank the 750 ml bottle.
If you like your beers bitter, Mikkeller has the beer for you — 1000 IBU. It is a double IPA with a theoretical 1,000 IBUs. So far, this beer has only been brewed once, but I will definitely give it a try if it is brewed again.
Other beers brewed by Mikkeller include All Others Pale, a pale ale; It's Alright, another pale ale; It's Alive, a Belgian strong ale; Jackie Brown, a wonderful brown ale; Big Worse, a barleywine; Draft Beer, an imperial pilsner; and Monk's Elixir, a Belgian quad.
Someday I hope to be able to try all of the Mikkeller. But, the only way I think that could ever happen is if they stop brewing, and there's no way I would want that to happen. The beers are too darn good.
Norman Miller is a Daily News staff writer. For questions, comments, suggestions or recommendations, email email@example.com. Check out The Beer Nut blog at http://blogs.wickedlocal.com/beernut. Also follow him on Twitter at www.twitter.com/realbeernut.


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Quick Tip: stage.mouseX on Android
When working with AIR on Android, I felt into an issue with stage.mouseX (stage.mouseY) returning value 107374182. It seems I am not the only one who experience that, but also Michael Ritchie and Lex Talkington did. This happens after you release touch screen. You may expect that Event.MOUSE_LEAVE would be fired in the right moment, but that sometimes just does not (sometime it does). I did not found any better solution than testing returned values against the static number, so I came up with this piece of code:
if(stage && (int(Math.abs(stage.mouseX)) == 107374182 || int(Math.abs(stage.mouseY)) == 107374182)) return;


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The Quare Place
Near Silloth, Dumfries & Galloway
Price from
No date selected, click below to add arrival date
Price from
No date selected, click below to add arrival date
Booking & Availability Calendar
A key to booking & availability
- Selected
- Unavailable
- Available
- Change over day
- Other possible start days
The Holiday Cottage
Dumfries & Galloway
Dumfries and Galloway is located on the South West corner of Scotland and extends right from the Scottish border to the Irish Sea. Here you will be dazzled by the beautiful gardens, fascinating history, and traditional arts and crafts. The most famous of the towns in the Dumfries and Galloway area has to be Gretna Green, a town which has become synonymous with weddings. Since 1754 couples have been coming to an unassuming blacksmith shop in Gretna Green to tie the knot and the tradition continues today. Why not spend your wedding night in one of our Dumfries and Galloway holiday cottages? A perfect romantic ending to a unique wedding day!
Reviews for The Quare Place, Dumfries & Galloway
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Have you stayed in this cottage? if so let us know what you thought of it by writing a review below..


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Sarah Lyall in the New York Times adds some color to the point I made in this weekend's column about Boris Berezovsky and Russian oligarchs. It's not some accident of climate or timezones that has made London the haven of choice for world's dubious money. It's deliberate state policy: in particular the policy that allows "non-domiciled" foreigners to live for extended periods in Britain while paying tax only on their British-source income, which is typically negligible. One of the (many) negative consequences of that policy is the shutting down of large areas of London as living neighborhoods.
An odd thing was happening, or rather not happening, as dusk fell the other day across Belgravia, home to some of the world's most valuable real estate: almost no one seemed to be coming home. Perhaps half the windows were dark. It seems that practically the only people who can afford to live there don't actually want to. Last year, the real estate firm Savills found that at least 37 percent of people buying property in the most expensive neighborhoods of central London did not intend them to be primary residences. … or single-family housing in the prime areas of London, British buyers spend an average of $2.25 million, Ms. Barnes said, while foreign buyers spend an average of $3.75 million, which increases to $7.5 million if they are from Russia or the Middle East.


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This regular expression matches a URL.
- https?://([-\w\.]+)+(:\d+)?(/([\w/_\.]*(\?\S+)?)?)?
- PHP Example: Automatically link URL's inside text.
- $text = preg_replace('@(https?://([-\w\.]+)+(:\d+)?(/([\w/_\.]*(\?\S+)?)?)?)@', '$1', $text);
CommentsSubscribe to comments
- Posted By: hathrill on August 20, 2009
Exactly what I needed. I heart you.
- Posted By: jpo on September 1, 2009
Perfect. Thank you!
- Posted By: cjastram on October 21, 2009
Perfect for copy-and-paste. Very nice regex, thank you! -cej102937
- Posted By: goozak on November 10, 2009
Great regex, thanks ! Small thing : the '-' (dash) is missing - URL like this fails (http://web5.uottawa.ca/admingov/reglements-methodes.html)
- Posted By: goozak on November 10, 2009
Great regex, thanks ! Small thing : the '-' (dash) is missing - URL like this fails (http://web5.uottawa.ca/admingov/reglements-methodes.html)
- Posted By: inhahe on November 28, 2009
it's also missing left parenthesis, right parenthesis, and comma.
- Posted By: tannerc on December 18, 2009
Perfect! I spent the better part of this morning looking for a great URL matching snippet and finally found it here. Thank you!
- Posted By: joshOiknine on January 14, 2010
Took me a few min to track this down on Google but it was exactly what I was looking for. Thank You.
- Posted By: chicagowebdeveloper on March 30, 2010
Does this work with links that do not have the "http" or "https" in front of it. like ubuntu.com for example?
- Posted By: keevkilla on July 9, 2010
I improved the regex given here, to take into account your comments : pregreplace('@((https?://)?(\w+.[-\w.]+)+\w(:\d+)?(/([-\w/.](\?\S+)?)?))@', '$1', $text);
Now with this regex, the links can be without any http:// or https:// block (like www.exemple.com) and can have multiple /folder/subfolder/file.htm after the domain, and finally "-" are considered as part as a standard URL.
Thanks for the first regex that helped me a lot find this one ! I hope mine will help the others.
- Posted By: keevkilla on July 9, 2010
just replace the regex by '@((https?://)?(\w+.[-\w.]+)+\w(:\d+)?(/(-\w/.?)?))@' because in my last post, some characters are missing because of misinterpretation...
- Posted By: keevkilla on July 9, 2010
Well it also removes the underscores... So I posted my contribution here : http://snipplr.com/view/36991/improvement-of-url-interpretation-with-regex/
- Posted By: keevkilla on July 12, 2010
Last (but not least) change of snippet location : http://snipplr.com/view/36992/improvement-of-url-interpretation-with-regex/
You need to login to post a comment.


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Underusing Medications Because of Cost May Lead to Adverse Health Outcomes - Article Cardiac Arrest; Cardiac Diseases; Endocarditis; Heart Disease; Heart Disease and the Mind-Body Constitution; Heart Disease, Congenital; Heart Diseases (General); Heart Diseases--Prevention; Heart Infection, Endocarditis
Article: Underusing Medications Because of Cost May Lead to Adverse Health Outcomes
Middle-aged and older Americans with heart disease who cut back on their prescribed medications because of cost were 50% more likely to suffer heart attacks, strokes, or angina than those who did not report cost-related medication underuse, according to a new study funded in part by the National Institute on Aging, part of the National Institutes of Health. Michele Heisler, M.D., M.P.A., at the Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, and colleagues
This is the first nationally representative longitudinal study to demonstrate that patients with serious chronic illnesses experience adverse health events when they restrict their use of prescription drugs due to cost. The downturns in patients' health were observed over a relatively brief (2-3 year) period, suggesting that cost barriers to prescription drug use may have important short-term effects on older patients' health and well-being, Heisler said.
"This study underlines how important medications can be and how important it is for people who need the medications to be able to get them," said HHS Secretary Tommy G. Thompson. "This is why a new drug benefit for Medicare was so crucial, including the interim drug card with its special benefit for low-income Americans. It's also why FDA is working to make generic products available quickly, as well as rapid review for significant new medications. We need to keep working toward better access to drugs and keep supporting the science that underlies ever-improving products."
The study included 7,991 middle-aged and older Americans who participated in a survey conducted between 1995 and 1996 as part of the Health and Retirement Study (HRS), an NIA-supported survey of adults aged 51 to 61, or the Asset and Health Dynamics Among the Oldest Old (AHEAD) Study, a national survey of adults aged 70 or older.
After controlling for risk factors for poor health outcomes, 32% of adults who had restricted medications because of cost pressures reported a significant decline in their self-reported health status during their follow-up interviews compared to 21% of adults with no cost-related underuse. Self-reports of health have been found to strongly predict other serious life events, including mortality, according to the study.
"There is a growing array of effective but often expensive prescription medications that clearly improve health outcomes, especially in the field of cardiovascular disease. As medications become even more effective, differences in access to prescriptions drugs because of cost may further worsen disparities in health outcomes between rich and poor Americans," Heisler said.
"This study suggests what can happen when older people cannot get the medications they need and will help inform policy regarding prescription drug insurance coverage," said Richard M. Suzman, Ph.D., NIA Associate Director for the Behavioral and Social Research Program. "The longitudinal design employed in this study suggests that the cost of drugs can lead to drug underuse and that this underuse could in turn contribute to adverse health outcomes. Additional research will be needed to further examine the causal relationship between drug costs and health outcomes."
In addition to cardiovascular declines, older individuals who restricted medication use because of cost had increased rates of depression, according to the study. Researchers found no health differences among people with arthritis and diabetes who said they had restricted drug use due to cost. Community-dwelling people over 65 paid an average of $410 for their drugs in 1999, and adults with multiple, chronic diseases paid twice as much, according to a cited study.
The NIA leads the Federal effort supporting and conducting biomedical, clinical, social, and behavioral research on aging. This effort includes research into the causes and treatment of memory declines and other cognitive problems associated with age. Press releases, fact sheets, and other materials about aging and aging research can be viewed at the NIA's general information Web site,
* The study was conducted by Michele Heisler, MD, M.P.A., Kenneth M. Langa, MD, Ph.D, Elizabeth L. Eby, M.P.H., A. Mark Fendrick, MD, Mohammed U. Kabeto, M.S., John D. Piette, Ph.D.
Veterans Affairs Center for Practice Management & Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI (MH, KL, ELE, JDP), Department of Internal Medicine (MH, KL, AMF, MUK, JDP), Michigan Diabetes Research and Training Center (MH, JP), Institute for Social Research (KL), Patient Safety Enhancement Program, (KL), University of Michigan School of Medicine, Ann Arbor, MI.
Heisler is a Veterans Affairs Center for Practice Management & Outcomes Research Career Development Awardee. Langa was supported by a Career Development Award from the National Institute on Aging, a New Investigator Research Grant from the Alzheimer's Association, and a Paul Beeson Physician Faculty Scholars in Aging Research award.
** The HRS and AHEAD are nationally representative, biennial longitudinal studies, sponsored by the National Institute of Aging and undertaken by the University of Michigan's Institute for Social Research. These studies target community-dwelling adults in the contiguous United States, with over-sampling of blacks, Latinos, and Florida residents, and gather in-depth economic, financial, and health information from respondents. In 1998, the two studies were combined into one HRS with identical survey procedures and questionnaires.
Source: National Institutes of Health
Cache Date: December 16, 2004


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Bravo, Brian Snow. We didn't think there was any way you could top last Friday night's trachea-shredding performance, as the Marist RedHawks hit a late three to win the 4A regional final over Curie, 63-62. No, there was no way you could top that one.
How wrong we were! In tonight's sectional semifinal, you were there to call history, as Marist came back from a 15-point fourth-quarter deficit, capped off by five points in the waning seconds to send the game to overtime. Marist (of course!) pulled out a 68-63 win in the end over Bogan and lived to play another game.
Brian Snow – a.k.a. @BigSnowman40 – we bow to your insatiable enthusiasm for the game of basketball. And with Gus Johnson unavailable for this year's NCAA tournament, your ultrasonic announcing prowess would be most welcomed come next week's slate of action.


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Two community areas saw their first homicide of 2011 in the last week, a RedEye analysis of preliminary police data found.
In Bridgeport, a 33-year-old man was shot to death Monday in the 3100 block of South Green Street, police said. The community area recorded two homicides last year, according to RedEye data.
In the Lower West Side, a 17-year-old boy was fatally shot June 16 in the 2000 block of South Canalport Avenue, police said. The community area recorded four homicides last year, RedEye data shows.
New City and Austin also recorded a gunshot homicide in the last week.
Thirty-four homicides have been logged so far this month. Police recorded 54 homicides in June last year, RedEye found.


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The Lost Years of Merlin (series) by T.A. Barron
Artemis Fowl (series) by Eoin Colfer
Ranger's Apprentice (series) by John Flanagan
Warriors (series) by Erin Hunter
Time of the Eagle by Sherryl Jordan
Skulduggery Pleasant by Derek Landy
Pendragon (series) by D.J. MacHale
Keys to the Kingdom (series) by Garth Nix
Percy Jackson & the Olympians (series) by Rick Riordan
Septimus Heap (series) by Angie Sage
Recommended for grades 9-12:
Abarat by Clive Barker
Dragons Keep by Janet Carey
Skin Hunger by Kathleen Duey
Beastly by Alex Flinn
The Faerie Path by Frewin Jones
Eragon by Christopher Paolini
Hawksong by Amelia Atwater-Rhodes
The Lord of the Rings by J.R.R. Tolkien
The Shadowmancer Returns by G.P. Taylor
The Once and Future King by Terence White
*Parents are responsible for the reading materials of their own minor children.


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A beautiful addition to any girl's room. Hang those hairbows on the skirt ribbons of this filly dress and they will be easy to find. The bodice of the dress is satin covered. The skirt is multi-layers of tuile.
- Adorned with bows and rhinestones
- Five ribbon holders each measuring 10 inches long
- Overall length is 19 inches
- Skirt measures 25 inches at the fullest
- Matching tuile hanger
- Package weight - 4 ounces
- Item #: BH014
- Manufacturer: Unbranded
Wholesale Tutu Bow Holders Hot Pink Black
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PBR Bart necesitaba un nuevo diseño de tema de wordpress y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 34 diseños de 9 diseñadores freelance.
PaperbackReader has been around since 2002 in various forms. Each time, I've done the coding myself, and until about a month ago, it was in a homerolled PHP/MySQL design. I got tired of keeping it up, and wanted the features that wordpress has to offer, so I'm in the process of switching over. In so doing, I've lost what my site looked like.
I have a theme that "works" the way I want, but it doesn't "look" the way I want.
There are essentially 2 pages:
The home page, which is a 3 column layout.
#1 is "Columns" that is, weekly pieces of 1000 words or more
#2 is "Reviews" sporadic reviews of 300-500 words
#3 is the admin stuff, advertising, archives, links, the general wordpress stuff
You can see the new layout here, I've lost the old one, sadly.
Then the content page, which is 2 columns
Column 1 is the content, and it spans column 1 & 2. Column 3 is still the admin stuff.
Here's what the content page used to look like:
That old page also has my old header and logo, the guy standing at the comic book spinner rack:
The audience is the market for comics, video games, superhero movies, etc. Here's an example of the leaders in the industry:
What I need is a new style sheet, and new images that go with the theme I have, lifestyle. I could also use some accent images, as well.
Please feel free to be over the top in the design, these are comic books, after all.
More info from a question:
Basically, I think a wordpress theme has two components. The way it works, and the way it looks.
I love the way it works, I need to separate "Column" postings from "Review" postings. Reviews come in at the rate of about 20 per week, and Columns about 3-5 per week. So I don't want them mixed up.
I would like something fairly splashy, with a good genre feel. I want to keep the structure/coding of how the wordpress theme works, but I want new colors, new images, etc.


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22 immigrants die as boats sink
A yacht and a dinghy crammed with immigrants trying to enter Greece capsized today in the eastern Aegean Sea, leaving at least 22 dead, including four children, and several more missing.
The vessels had been trying to enter Greece illegally when they overturned before dawn off the coast of the island of Samos near the Turkish coast. It was not immediately clear what caused the overloaded craft to capsize. This was the third fatal migrant boat disaster this year.
The Greek coast guard said 36 people - 32 men, three women and a child - were rescued, and two of them - a man and a child - were airlifted to a hospital on the mainland. The survivors were identified as 23 Somalis, nine Syrians and three Eritreans, the coast guard said. The child's nationality or the nationalities of those who died were not immediately known.
Coast guard officials recovered the bodies of two women, a man and a boy from the sea, and later found a further 18 bodies - including three children - inside the yacht after it was towed to Samos.
Survivors told the coast guard between 60 and 65 people had been on the 30-ft yacht and the six-foot dinghy that had set off from Turkey.
"We can't give a precise number of missing people with any certainty," said Coast guard spokesman Nikos Lagadianos.
Coast guard vessels, fishing boats and two search and rescue helicopters were combing the area for survivors or bodies. A nearby cruise ship helped for several hours before being cleared to continue its journey.
Despite the deep financial crisis that brought Greece to the brink of bankruptcy four years ago, the country remains a major entry point for people from poor or war-ravaged parts of Asia and Africa seeking a better life in the 28-nation European Union.
Fatal accidents are frequent as migrants risk the dangerous sea crossing from Turkey. Before today's incident, 21 people had drowned in similar incidents since the beginning of the year.
Over the weekend, the Greek coast guard rescued about 250 immigrants from the sea.


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MILPITAS, Calif., Jan. 22, 2014 - The board of directors of SanDisk Corporation (NASDAQ:SNDK), a global leader in flash storage solutions, has declared a first quarter 2014 cash dividend of 22.5 cents per share on the company's common stock. The dividend will be payable on February 24, 2014 to stockholders of record at the close of business on February 3, 2014. Future dividends will be subject to approval by SanDisk's Board of Directors.
SanDisk Corporation (NASDAQ: SNDK), a Fortune 500 and S&P 500 company, is a global leader in flash storage solutions. For more than 25 years, SanDisk has expanded the possibilities of storage, providing trusted and innovative products that have transformed the electronics industry. Today, SanDisk's quality, state-of-the-art solutions are at the heart of many of the world's largest data centers, and embedded in advanced smart phones, tablets and PCs. SanDisk's consumer products are available at hundreds of thousands of retail stores worldwide. For more information, visit www.sandisk.com.
Investor Contacts:
Jay Iyer
Brendan Lahiff
Media Contact:
Lee Garvin Flanagin
© 2014 SanDisk Corporation. All rights reserved. SanDisk and the SanDisk logo are trademarks of SanDisk Corporation, registered in the United States and other countries. Other brand names mentioned herein are for identification purposes only and may be the trademarks of their respective holder(s).


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There are no signs of foul play in the explosion in a Ball Hill Road house that claimed the life of the occupant Thursday, a spokesman for District Attorney Joseph P. Early said this morning. The resident, Rick Conway, 61, was the only person home at the time of the fiery blast.
"We believe this was some sort of gas explosion," said acting Fire Chief John Bennett. He cautioned, however, that it was still early in the investigation.
"The explosion blew the whole front of the house out," he said, adding that the split-level home's windows had blown out to the front and back yards, and the entire house was engulfed in flames.
Authorities initially did not release the victim's name pending an autopsy by the medical examiner.
The fire was reported by a woman who was passing by the house when she heard the explosion and called 911. It burned for more than an hour.
Chief Bennett, on vacation from his full-time job when he got the call just after 10:30 a.m., was the first to arrive at the fire. He said he made it to the front door, but the intense fire forced him back. Three additional alarms were immediately struck for manpower and water. Westminster, Holden, Hubbardston and Sterling firefighters quickly arrived to assist Princeton firefighters. Princeton has an on-call department. There are no hydrants in town, so the first firefighters had to break ice on a nearby pond before laying more than 2,000 feet of 5-inch hose, a process that took about 10 minutes, according to Chief Bennett. Rutland and Hubbardston companies brought their water tankers.
Neighbors say Mr. Conway had been living in the house that belonged to his mother, who had recently moved to a nursing home. The house is owned by Daveeda A. Conway, according to town records.
A car and a tractor-trailer rig, which neighbors said belonged to Mr. Conway, were still parked in the driveway as firefighters arrived and worked to extinguish the blaze. Fire officials became worried that someone may have been at home at the time of the fire because the driveway had not been plowed.
"The whole building literally exploded," Chief Bennett said.
He ordered firefighters evacuated several times because of the intensity of the heat, and the floors in the front of the house were sagging and unstable. About 85 firefighters were at the scene, and there were four accountability checks throughout the fire.
"It's been quite a challenge," Chief Bennett said of firefighting efforts. An oil tank in the basement caught fire, according to officials, and there were propane tanks inside and outside the house. The propane tank outside the house did not catch fire.
Initial reports of oxygen tanks in the cellar left behind by Mrs. Conway did not turn out to be true, according to state Fire Marshal Stephen D. Coan.
Fire Marshal Coan said the exact cause of the explosion was still under investigation by state troopers assigned to the fire marshal's office, and local officials. He said several witnesses gave statements that they heard an explosion.
Fire Marshal Coan said the victim was found in an office in the rear of the home near an adjacent bedroom. When asked if the man may have been trying to escape from the burning building, the fire marshal said he did not know.
"Those are the details we'll never know," he said.
"It's a disaster," said Greg Dowdy, a neighbor who shook his head and at times held back tears as he surveyed the wreckage. He said he was on Wachusett Mountain when the explosion occurred, and he came home after his wife called him.
"He was a tractor-trailer driver, and he was home only on the weekends. He seemed to be a real nice guy," he said.
Another neighbor, Todd Smolenski, said he was clearing snow when he saw thick smoke. His two sons were on vacation from school this week, so the three walked down to the blue house.
"Fire was coming out of every window," Mr. Smolenski said.
The fire and smoke were fully extinguished by early afternoon, and the mood was quite somber. State fire investigators arrived and cordoned off the area with yellow tape.
Cathy Clary, a neighbor, took pictures of the remains of the house, and wondered what happened to cause the devastation. She knew the man drove a tractor-trailer truck and had lived there for some time.
"What a shame," Ms. Clary said, as she waited for answers to what happened. She said the fire was the third on Ball Hill Road recently. The other two fires were minor, she said.
"I'm a little freaked out, to be honest with you," Ms. Clary said.


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Cody Henrichs
Rhode Island School of Design
Faculty Sponsor: Dean Snyder
Artist StatementPrecarious, and often cryptic, my objects, films, and paintings act as vehicles for narrative investigations into masculinity, abandonment, nature, co-dependency, sexual desire, power, speed, love, and loss. My sculpture is both a physical and conceptual structure through which I can attempt to address uncontrollable forces, a space to address the chaos, where I can see the subtle poetry of my life with more clarity.
Website Design & Development by Cybermill Interactive


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Convicted money manager to pay $1.45M settlement
NEW YORK A hedge fund founder serving the longest prison term ever given for insider trading also will be writing the government another big check.
Raj Rajaratnam, a one-time billionaire convicted last year of trading on inside information, will pay nearly $1.45 million to settle a civil case brought by the Securities and Exchange Commission, court documents show. A federal judge on Thursday approved the deal, which requires Rajaratnam to pay the settlement within 90 days and waive any right to appeal it.
- Why the inside-trading crackdown misses the mark
- Feds probing insider trading by Goldman Sachs exec
- Ex-Goldman director sent to prison for insider trading
The documents say the settlement includes $1.29 million representing "profits gained and losses avoided" as a result of trading on tips from a former Goldman Sachs (GS) director convicted separately in June. The settlement also includes $148,000 in prejudgment interest.
The Sri Lanka-born Rajaratnam, who founded the New York-based Galleon Group of hedge funds, previously was ordered to pay a record $92.8 million civil penalty to the SEC.
In the criminal case against him, he was fined $10 million and was ordered to forfeit $53.8 million in what U.S. District Court Judge Jed Rakoff said last year were illicit profits from trading on confidential corporate information.
Prosecutors said Rajaratnam earned as much as $75 million in illegal profits in a case that resulted in more than two dozen convictions. They said he acted on secrets he got from friends and colleagues in the securities industry and at public companies.
Rajaratnam was convicted thanks largely to wiretaps prosecutors used to back up their claim that he made a fortune by coaxing a crew of corporate tipsters into giving him an illegal edge on blockbuster trades in technology and other stocks. His defense argued that the tapes revealed nothing more than that he was doing his duty by asking questions about information already circulating in the "real world" of high finance.
Rajaratnam, 55, is serving 11 years at a Massachusetts federal prison and has appealed.


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PBN necesitaba un nuevo diseño de logotipo y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 66 diseños de 17 diseñadores freelance.
Plant By Nature, LLC. We are a developer, manufacturer and worldwide marketer of a wide variety of organic, eco-friendly, petrochemical-free nutrients for plants, agricultural crops, trees and shrubs. Our products have been proven in testing to increase crop yields and crop quality significantly and shorten growing cycles. Our goal is to help farmers and growers in all parts of the world to increase the quality and quantity of crops grown in all kinds of environments, from traditional farms to multilevel urban greenhouses.
We are looking for a logo to present this focus both in print (e.g., on product labels, stationery, promotional materials, etc.) and on the web.
We want to reach people —anywhere in the world—who are serious about growing things, e.g., farmers, growers of fruit trees, shrubs, etc., and also government agricultural ministries, college agriculture programs—anyone that has a vested interest in improving the quality/quantity of the plants, trees and shrubs they grow.
Scalability— logo should maintain good image quality in all sizes from thumbnail on up. Best to use a standard vector graphics file format.
Should not have a cartoonish feel, but also not overly elegant.
Include "Plant-By-Nature" name in the design. Try not to use script fonts
Color scheme? Lush greens and earth/wood tones encouraged. (but tomato, pumpkin and/or squash colors ok, but should not predominate).
Go here: http://www.plant-by-nature.com/imag…gelib.html
for a gallery of images to use for inspiration, if need be (sorry—I don't have images of tomatoes, squash or pumpkins). Also there for reference are three logos we have used in the past , which (except maybe for the last one) should NOT be used for inspiration. Feel free to incorporate any part of any image in the design.
We think this logo will be used mostly against white, light green and/or tan, etc., backgrounds.
Descubre cómo funciona un concurso de diseño u obtén más información sobre nuestros servicios de diseño de logo.


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The Entertainment Economy Is Completely Different Than It Was/
Make no mistake: The Entertainment Economy can no longer be predicated on scarcity or control -- as it has been for the last 110 years. We need to rebuild it around concept of super-abundance & access.
"YouTubers Upload 72 Hours of Video Every Minute" That's up from 48 hours a year ago. At what age do we reach Saturation Point? I already have: I have identified every film I would like to see -- if I am able to maintain my maximum rate of consumption -- to carry me 5 years past my life expectancy. The very nature of technology indicates that in less than ten years, a twenty year old cinephile will have done the same. I expect that to happen much sooner though. Audiences will have no "need" for the new. We have so many cute animals and children doing silly things after all. Who really needs an ambitious and relevant cinema? So why do anything to preserve it (let alone advance it)? Let's just bury our heads and try to hold onto what is left of our jobs. Right?
I am glad there are those that know otherwise.


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A man accused of posting sexually explicit images of women to a website to extort them for money will go to trial on 31 felony counts, a judge said Monday.
Kevin Bollaert had a five-day preliminary hearing in a San Diego courtroom, facing felony counts of conspiracy, identity theft and extortion. Afterward, Judge David Gill decided enough evidence existed for Bollaert to move forward to trial.
The 27-year-old will be arraigned on the charges on July 16.
Bollaert had argued he wasn't guilty because he simply received the images from the women's ex-boyfriends.
But 16 women claim Bollaert took their photos, posted them to the website YouGotPosted.com and then asked them to pay hundreds of dollars to have the pictures removed.
Investigators say Bollaert posted more than 10,000 sexually explicit photos of women on YouGotPosted.com.
According to an arrest warrant, he then created ChangeMyReputation.com, where he allegedly charged the women $300 to $350 have their pictures removed from YouGotPosted.com.
According to investigators, Bollaert made $900 a month off advertising on his websites and thousands more from women desperate to have their pictures removed.
Both websites have been shut down.
The so-called "revenge porn" case is the first of its kind, filed by state Attorney General Kamala Harris.
There is now a California law that prohibits posting identifiable nude photos online after a breakup, punishable with a $1,000 fine or six months in jail.


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Friends of Toowong Cemetery
The Friends of Toowong Cemetery is a voluntary organisation of people with a special interest in the Toowong Cemetery (formally known as the Brisbane General Cemetery), located in Toowong, Brisbane, Australia.
The Toowong Cemetery is the largest cemetery in Queensland and is an important record of the history of Brisbane and Queensland. It was officially opened in July 1875 and over 127,000 people are buried there. Toowong Cemetery is an operating cemetery.
- Location:


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Apple has been pretty hush hush about its search for a new SVP of retail following the unexpected departure of retail boss John Browett.
As John Paczkowski of AllThingsD reports, Apple can't afford to make another hiring mistake. So for the last several weeks, Paczkowski has been poking around to find ideal candidates.
He found three from inside Apple who would be a good fit for the position:
- Steve Cano, Apple's manager of retail stores
- Bob Bridger, Apple VP for Retail Real Estate and Development
- Jeremy McDougal, Apple VP of Retail
His sources are divided over who would be best suited to lead Apple's retail operations. One says McDougal would be best, considering that he already has the VP of Retail title. But another says Cano would be best because he's the most well-rounded out of the three and understands Apple's retail store culture.
Paczkowski also named five candidates from outside of Apple that Apple would be lucky to hire away, given their experience working for global consumer brands:
- Angela Ahrendts, CEO, Burberry
- Victor Luis, President, International Group at Coach
- Jeanne Jackson, President, Director to Consumer at Nike
- John Culver, President, Starbucks Coffee China and Asia Pacific
- Paul Gainer, Executive Vice President, Global Disney Store
However, it would be a hard sell to get these people to leave those powerful positions and join Apple because, as one of Paczkowski's source said "Apple is not a true retailer."
For now, the retail team reports directly to Apple CEO Tim Cook and Cook is expected to take his time to find a replacement.


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For ages: 8-and up
Dark Horse presents the definitive guide to Star Wars comics, complete with in-depth coverage all the way through Episode III! Written by Ryder Windham, Star Wars expert, and densely illustrated with both brand-new art and classic images from the comics, this chronological compendium contains everything you need to be the ultimate Star Wars reader in-the-know. Follow Anakin Skywalker's descent into darkness, from his early days as a padawan, to his harrowing Clone Wars battles, up through his transformation and eventual death as Darth Vader. Get complete details on the exploits of Luke and Leia, Han and Chewie, and all the rest of the gang, with thorough rundowns of classic Star Wars tales originally printed decades ago! Spanning over 25,000 years of Star Wars history, from the very beginnings of the Jedi order, no character goes unmentioned and no quadrant goes unmapped.


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HPV vaccine now recommended for all boys, CDC says
(CBS) The HPV vaccine should be given to all males between the ages of 11 and 21, says the Centers for Disease Control and Prevention.
PICTURES: HPV vaccine: 20 states that shun the shot
The CDC's Advisory Committee on Immunization Practices said in its 2012 recommendations, that the human papillomavirus vaccine should be "routine" for all boys aged 11 to 12 years old and it also recommends "catch-up" vaccinations for males ages 13 to 21.
Last October, the committee first recommended the vaccine for boys, HealthPop reported, but the recommendations weren't formalized until they were published this week, according to the CDC. The recommendations are published in the Feb. 1 issue of the Annals of Internal Medicine, and the Feb. 3 issue of Morbidity and Mortality Weekly Report.
The immunization committee is comprised of 16 other medical societies, including the American Academy of Pediatrics and the American College of Physicians.
CDC epidemiologist Dr. Eileen Dunne told the New York Times that the move came because new data over the past two years showed the vaccine was "very effective" in preventing genital warts in men and women, as well as some cancers.
At least 50 percent of sexually active men and women get infected with HPV at some point, but few develop symptoms or get sick, according to the CDC. Some infections lead to warts, cervical cancer and other cancers, including of the head and neck.
A recent study found that 16 million Americans between the ages of 14 to 69 have HPV in their mouths or throat, but most were found not to have the kind most strongly linked to cancer, according to HealthPop.
The HPV vaccine has been recommended for girls since 2006, but only 49 percent of adolescent girls have gotten at least one of the three HPV shots, according to recent estimates.
The new HPV vaccine recommendations were just two of the changes the CDC announced. Changes were also made to when mothers should receive the tetanus, diphtheria, and acellular pertussis (Tdap) booster that protects infants from pertusiss. According to the 2012 schedule, women should receive the vaccine during pregnancy, preferably after 20 weeks of gestation. Adult patients should continue to be vaccinated against influenza.


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The Millikin football team defeated Aurora University 44-20 on Sept. 22 at Frank M. Lindsay Field in front of a large Fall Family Weekend crowd.
Millikin scored the game's first 14 points with two first quarter touchdowns. The Big Blue scored on its first possession when Matt Holmes hit Sean Dunning on a 14 yard pass to make it 7-0.
Erik Tobey's 92 yard punt return made it 14-0 Millikin.
Aurora pulled within seven in the first quarter's final minute on a 36 yard pass from Jimmy Bevell to Michael Beasley Hart.
Millikin made it 21-7 with 32 seconds left in the half when Holmes hit Alex Chiligiris on a three yard pass play.
Millikin put the game away with three touchdowns in the third quarter.
A Dunning one yard run opened the third quarter scoring. Big Blue linebacker Marquette Moore recovered an Aurora fumble and raced 66 yards for a touchdown to make it 35-7 Millikin. The Big Blue's third touchdown of the quarter was set up by an Adam Rosner fumble recovery. A five yard touchdown pass from Holmes to Dunning made it 42-7.
Millikin would add two points in the fourth quarter when Christian Silva returned a blocked extra point for a defensive conversion. Darrell Mitchell had the block for the Big Blue.
Dunning finished the day with 95 yards rushing. Holmes rushed for 64 yards and was 10-16-1 passing for 137 yards and three touchdowns. Justin Brooks rushed for 90 yards.
Brandon Trujillo had 137 yards rushing for Aurora. Bevell was 15-28 passing for 151 yards with three scores.
Mitchell was Millikin's top tackler with 10 including one tackle for a loss.
Moore had nine tackles as did Jake Hazelton.
Brandon Haase led the Spartan defense with nine tackles.
Millikin opens CCIW play on Sept. 29 at Illinois Wesleyan in Bloomington, Ill. with a 6 p.m. kickoff.


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The Miracle of Birth, With a Side of Raspberry Jam
It all started with the first censored Cake Wreck:
Remember when I first posted this four years ago? How shocking it was back then?
Ahh, those were the days.
Unfortunately, wreckerators thought edible birth scenes were a BRILLIANT idea, and suddenly there were fondant babies popping out of raspberry jam-smeared vajay jays everywhere. And for some odd reason, I can't help but feel just a teensy bit responsible.
I am become death, the destroyer of wombs.
You might think the more cartoonish versions would be less traumatizing, but only if you've never seen the amount of pubic hair sprinkles that I have. Yeah, you heard me: PUBIC HAIR SPRINKLES. If I have to see it, the least you can do is imagine it.
Do you see the size of that censor box? DO YOU?
Let's just say there are five people at that shower who will never eat chocolate sprinkles again.
And the sixth will never kiss the top of her kids' heads again.
You'll also note that the pubic hair sprinkles are shedding/spreading down mom's legs. You will note this, because I won't let you not note it, and also because I'm really enjoying typing "pubic hair sprinkles."
Question: Where are this poor woman's arms?
And why does she have two pumpkins on her chest? And should we be happy the baby is smeared in white icing instead of raspberry jam?
Which reminds me of a:
TRUE STORY I COULD NOT POSSIBLY MAKE UP: I've attended one birth in my life (beside my own, of course, but the view that time was terrible), and the baby was a "cheesecake baby." Nurses, feel free to explain that in the comments. Everyone else, good luck not remembering this the next time you're eating cheesecake.
I'd really hoped this kind of insanity was contained to just the U.S., but no.
I'm not sure what's coming out of that woman, but it looks like the volleyball head from Castaway floating in intestines. (The censor bar says, "You're welcome.")
And speaking of censor bars, this final cake was so explicit that it was actually impossible to make a censor bar large enough, so we've done the reverse: covered everything except a small circle. Even that is pretty graphic, though, so scroll with caution - and don't say I didn't warn you. ;)
You guys, I never thought I'd say this, but... I miss belly cakes.
(You know it's bad when a C-section cake is less traumatizing, am I right?)
Thanks to Tessa L., Ginn, Christina T., Karen H., and Amanda N., and an extra big and bloody thanks to Laura of Mamma Jamma Cakes, the baker of the most explicitly realistic birth cake I've ever had the misfortune of seeing in all its uncensored glory.
Laura actually sent me the cake herself, explaining that even though she managed to gross herself out with it, she's still especially proud of the "skin tone and blemishes." If your morbid curiosity is compelling you to see the full, uncensored version - and I know it is - then you can see it HERE. (EXTREMELY NSFW. You have been warned!)


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Promoting success at school and in life -
one child and one afternoon at a time.
One of the surest paths to a happy and productive life begins with success at school – starting in the early years. Yet many children struggle in elementary school. But the good news is – when addressed early on – it takes just a little compassion and initiative to give these young people a boost that can last their whole lives.
Children's After School Achievement (CASA), a community program of Hope College, was formed in 1987 to do just that in Holland, Michigan. CASA helps at-risk school kids before they slip through the cracks by providing free after-school tutoring and individualized summer school in addition to other educational and cultural-enrichment programs. In our first 20 years, hundreds of West Michigan youngsters have benefited tremendously through CASA. And we want to keep on making this positive difference for many more years to come.
CASA succeeds thanks to intentional programming, our dedicated staff, volunteers and generous supporters and financial contributors. Whether you are or might like to become a volunteer, donor, supporter, referring teacher or program participant, this site will help you join us in this important cause.
Help us get funding through IIC at no cost to you! Click to learn more about IIC.
Hope College | CASA | Holland, MI 49423
email@example.com | phone: 616.395.7944 | fax: 616.395.7453


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Mario runs into Jayden and Dallas, and decides to have a good ol' fucking time with these two studs. He's been curious, but now he's about to have his first gay experience, and discovers he loves big dick more than he realized!
AJ was getting a little pissed off after he was fooled over to the guy's pad, and he saw their true intent. It took some work to persuade this Asian in to turning loose some of that sweet culito, but Ricky and Kiko somehow nabbed that virgin asshole. Poked in the brown-eye, by a round-eye's one-eye.
Trolling for some straight dick and ass, Nico came across Alex hangin' out on the swing of a local park. Naive Alex proved to be a worthy candidate to be seduced into having His First Gay Sex. Alex was no stranger to his curiosity, only to fulfilling it. See it all unfold!
Michael locked his keys outside of his car when he ran into our gay asses. We decided to help him out by giving his virgin asshole a tune-up. Vroom! Vroom! Watch Michael sixty nine and cross that line into sissy la la land. Cum see it all now!!!
Troy was having a tough week so he went in for a full body massage. Ethan wanted to help our buddy out with his tension. He didn't realize what Troy really needed was a juicy dick sucking. Watch Troy troll his black pole and catch a couple nibbles from his new friend.
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