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Drug Information
- Common uses
- How to take the medication
- Common side effects
- Precautions & interactions
How Bortezomib works, side effects, interactions and precautions.
(bor tez' oh mib)
Brand Name(s): , Velcade®
WHY is this medicine prescribed?
Bortezomib is used to treat people with multiple myeloma (a type of cancer of the bone marrow) who have already been treated with at least one other medication. Bortezomib is also used to treat people with mantle cell lymphoma (a fast-growing cancer that begins in the cells of the immune system) who have already been treated with at least one other medication. Bortezomib is in a class of medications called antineoplastic agents. It works by killing cancer cells.
Are there OTHER USES for this medicine?
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
HOW should this medicine be used?
Bortezomib comes as a solution (liquid) to inject into a vein. Bortezomib is given by a doctor or nurse in a medical office or clinic. It is usually given on a rotating schedule that alternates 2 weeks when bortezomib is given twice a week with 10 days when the medication is not given. During the weeks that bortezomib is given, doses will always be at least 72 hours apart. The rotating schedule may be followed for up to eight cycles. After that, your doctor may decide to continue your treatment, but you will receive bortezomib less often.
Be sure to tell your doctor how you are feeling during your treatment. Your doctor may stop your treatment for a while or decrease your dose of bortezomib if you experience side effects of the medication.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
What SPECIAL PRECAUTIONS should I follow?
Before using bortezomib,
- tell your doctor and healthcare provider if you are allergic to bortezomib, mannitol, any other medications, or boron.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, or nutritional supplements you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone, Pacerone); cimetidine (Tagamet); clarithromycin (Biaxin, Prevpac); diltiazem (Cardizem, Dilacor, Tiazac, others); erythromycin (E.E.S., E-Mycin, Erythrocin); fluvoxamine; certain antifungals such as itraconazole (Sporanox) or ketoconazole (Nizoral); medications to treat diabetes or high blood pressure; certain medications to treat human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) such as indinavir (Crixivan), nelfinavir (Viracept), or ritonavir (Norvir); certain medications to treat seizures such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin, Phenytek); mibefradil (no longer available in the U.S.); nefazodone; rifabutin (Mycobutin); rifampin (Rifadin, Rifamate, Rimactane, others); troleandomycin (TAO) (no longer available in the U.S.); or verapamil (Calan, Covera, Isoptin, in Tarka, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you or anyone in your family has or has ever had heart disease and if you have or have ever had a herpes infection (cold sores, shingles, or genital sores); diabetes; fainting; high cholesterol (fats in the blood); low or high blood pressure; peripheral neuropathy (numbness, pain, tingling, or burning feeling in the feet or hands) or weakness or loss of feeling or reflexes in a part of your body;or kidney or liver disease. Also tell your doctor if you smoke or drink large amounts of alcohol.
- tell your doctor if you are pregnant or plan to become pregnant. Bortezomib may harm the fetus. Use birth control to prevent pregnancy during your treatment with bortezomib.Ask your doctor if you have questions about types of birth control that will work for you. If you become pregnant while using bortezomib, call your doctor immediately.
- do not breast-feed during your treatment with bortezomib. After your treatment has finished, talk to your doctor or nurse about when it is safe to restart breast-feeding.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using bortezomib.
- you should know that bortezomib may make you drowsy, dizzy, or lightheaded, or cause fainting or blurred vision. Do not drive a car or operate machinery or dangerous tools until you know how this medication affects you.
- you should know that bortezomib may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common in people who have fainted in the past, people who are dehydrated, and people who are taking medications that lower blood pressure. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
What SPECIAL DIETARY instructions should I follow?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.
Drink plenty of fluids every day during your treatment with bortezomib, especially if you vomit or have diarrhea.
What should I do IF I FORGET to take a dose?
If you miss an appointment to receive a dose of bortezomib, call your doctor right away.
What SIDE EFFECTS can this medicine cause?
Bortezomib may cause side effects. Tell your doctor if any of these symptoms, or those in the SPECIAL PRECAUTIONS section, are severe or do not go away:
- general weakness
- nausea
- vomiting
- diarrhea
- stomach pain
- anxiety
- back pain
- bone, joint, or muscle pain
- muscle cramps
- difficulty falling asleep or staying asleep
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- pain, burning, numbness, or tingling in the hands or feet
- weakness in the arms or legs
- changes in the sense of touch
- shortness of breath
- cough
- swelling of the feet, ankles, or lower legs
- hives
- rash
- itching
- difficulty breathing or swallowing
- swelling of the face, throat, tongue, lips, eyes, or hands
- hoarseness
- fever, sore throat, chills, or other signs of infection
- unusual bruising or bleeding
- black and tarry stools
- red blood in stools
- bloody vomit
- vomiting material that looks like coffee grounds
- slurred speech or inability to speak or understand speech
- loss of balance or coordination
- loss of memory
- paralysis (loss of ability to move a part of the body
- vision changes or loss of vision
- loss of consciousness
- excessive tiredness
- pale skin
- fast heartbeat
- fainting
- headache
- thoughts of harming or killing yourself
- difficulty thinking clearly, using good judgment, or understanding reality
- hallucinating (seeing things or hearing voices that do not exist)
- confusion
- restlessness
- thirst
- decreased urination
- loss of appetite
- constipation
- seizures
- skin blisters that are itchy or painful
Bortezomib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What should I know about STORAGE and DISPOSAL of this medication?
Bortezomib will be stored in the medical office or clinic.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at [WEB]. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include the following:
- fainting
- dizziness
- blurred vision
- unusual bruising or bleeding
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to bortezomib.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.
The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.
AHFS® Patient Medication Information™. © Copyright, 2019. The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: May 1, 2010.
Bortezomib is commonly used to treat:
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Genomics and Proteomics Reagents, Research Kits and Analytical Instruments Market is Expected to Grow to USD 52.3 Billion Globally by 2019: Transparency Market Research
21 Aug, 2013, 14:30 BST
ALBANY, New York, August 21, 2013 /PRNewswire/ --
According to a new market report published by Transparency Market Research (http://www.transparencymarketresearch.com) "Genomics and Proteomics Reagents, Research Kits and Analytical Instruments Market (Sample Preparation, Electrophoresis, BioChips and Microarrays, Chromatography, Mass Spectrometry, Thermal Cyclers, Next-Gen Sequencing) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019," in 2012, the global genomics and proteomics reagents, research kits and analytical instruments market was valued at USD 23.8 billion and is expected to grow at a CAGR of 12.1% from 2013 to 2019, to reach an estimated value of USD 52.3 billion in 2019.
Browse the full report at http://www.transparencymarketresearch.com/proteomics-market.html
The global genomics and proteomics market is expected to experience a growth in revenues at a CAGR of 12.1% during the forecast period, mainly due to exponential growth in preclinical and clinical research in drug discovery and disease identification. Since global incidence rates of cancer, diabetes and genetic diseases are on a rise, the market revenue growth is inevitable. Moreover, other emerging applications such as forensics and agriculture are also contributing to the growth which in turn has increased the number of research projects all over the world particularly in genomics. Proteomics has grown with increasing interest in protein mutations due to changes in genome and has given rise to a unique field of proteogenomics which is carving a commercial position for itself.
Genomics and proteomics reached a major milestone after the completion of Human Genome project in 2001. During the process, the research industry realized the need for affordable methods to sequence genomes of other organisms as well. This led to a revolution in life science analytical research tools and technologies such as thermal cyclers, mass spectrometry, and gel electrophoresis. An impressive genome database of various organisms is available today for researchers through various sources such as gene banks. Advancing technology and miniaturization of memory devices in electronics and semiconductors has also played a very significant role in creating this accomplishment. Several rare and unknown diseases such as autism, Alzheimer's along with high incidence diseases such as cancer and diabetes are currently being addressed through these technologies by drug discovery, disease identification and structural dynamics of proteins.
Related & Recently Published Reports by Transparency Market Research
A large fragmented market indicates high competitive pricing and no loss in quality of products, thus buyers have multiple options to choose from. Unique software for each application and company specified reagents for machines have reduced the negotiating power of buyers as companies do not guarantee good results without usage of company recommended reagents or software solutions. Customer loyalty is very low as researchers are keen to experiment with different products that may yield better results. A high number of acquisitions and mergers in the field of biotechnology indicate the nature of the market. New technological innovations are taking place on a regular basis. Patenting these products and commercializing them is a challenging task for new entrants in the face of giants such as Agilent, Thermo-Scientific, Waters and other players. Thus joint ventures and collaborations with existing players give an excellent platform for new entrants to expand in this field. The threat of new entrants is high and is expected to remain so throughout the forecast period.
Key players leading the genomics and proteomics market are Thermo Fisher Scientific, Agilent Technologies, Life Technologies, Qiagen and Illumina. Intense competition has lowered prices for all types of technologies and is expected to continue further. Miniaturization of technologies such as lab-on-a-chip, biochip and microarray lead the research along with miniaturization of other analytical instruments such as portable mass spectrometers and thermal cyclers.
North America was the largest regional market by revenue in 2012, due to regular break-through innovations in technology that have been introduced in several genomic and proteomic areas. Continued investment in healthcare and medical research is another factor responsible for steady growth in North America. Asia-Pacific and Latin America are expected to show the fastest growth through the forecast period.
Related & Recently Published Reports by Transparency Market Research
The global genomics and proteomics market is segmented into the following categories:
Genomics and Proteomics Market, by Reagent and Research Kits
- Sample Preparation Kits
- Prepackaged Sample Preparation Kits for PCR
- Prepackaged Sample Preparation Kits for Chromatography
- Prepackaged Sample Preparation Kits for Mass Spectrometry
- Prepackaged Sample Preparation Kits for Electrophoresis
- Purification Kits
- Electrophoresis Kits
- Capillary Electrophoresis
- Gel Electrophoresis
- BioChips and Microarrays
- DNA BioChips and Microarrays
- Protein and Peptide BioChips and Microarrays
Genomics and Proteomics Market, by Analytical Instruments
- Chromatography
- Gas Chromatography
- Liquid Chromatography
- Mass Spectrometry, by Analyzers
- Tandem Mass Spectrometry
- Time-Of-Flight Mass Spectrometry
- Quadrupole Mass Spectrometry
- Fourier Transform Mass Spectrometry
- Others (Magnetic Sector, Orbitrap, Ion Trap)
- Thermal Cyclers
- Digital Thermal Cyclers
- Conventional or Traditional Thermal Cyclers
- Real-Time Thermal Cyclers
- Next Generation Sequencing
Genomics and Proteomics Market, by Geography
- North America
- Europe
- Asia-Pacific
- Rest of the World (RoW)
Browse all Pharmaceutical Market Research Reports @ http://www.transparencymarketresearch.com/pharmaceutical-market-reports-1.html
Upcoming Reports in Pharmaceutical Market
Antithrombotic/Anticoagulant Drugs Market
Healthcare/Medical Simulation Market
Radiofrequency Ablation Market
About Us
Transparency Market Research is a global market intelligence company, providing global business information reports and services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insight for thousands of decision makers. We are privileged with highly experienced team of Analysts, Researchers, and Consultants, who use proprietary data sources and various tools and techniques to gather, and analyze information.
Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.
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SOURCE Transparency Market Research

subset: commoncrawl


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Monday, October 21, 2013
By-elections called, by-elections polled
In Bourassa, Emmanuel Dubourg led with 47% support against 18% for Stéphane Moraille of the NDP. The Bloc Québécois followed with 15% and the Greens with 12%. However, Forum listed Daniel Mailhot and Georges Laraque as the candidates for the Bloc and Greens. The actual Bloc candidate is Daniel Duranleau (Mailhot ran in 2011), though I don't suspect that would make much of a difference. But Laraque is no longer the Green candidate, and that absolutely would make a difference. If Laraque's vote is cut in half or more, where would it go? Moraille seems like the obvious destination.
The numbers in Brandon-Souris were the most surprising of the set, with Rolf Dinsdale of the Liberals leading with 39% to 35% for Larry Maguire of the Conservatives. The NDP and Greens were tied at 12% apiece. Considering the riding was easily won by the Tories in 2011 and that the Liberals got 5% of the vote, this is a remarkable turnaround.
In Provencher, the Conservatives' Ted Falk led with 56% to 29% for Terry Hayward of the Liberals, another strong showing for the party (they had 7% here in 2011). The NDP followed with just 9%, while the Greens were at 6%.
And in Toronto Centre, which had the largest sample of the bunch by far, the Liberals' Chrystia Freeland led with 45% to 30% for the NDP's Linda McQuaig. That generally matches where the parties were in 2011. The Conservatives were third with 18%, while the Greens had 7%.
The numbers look good for the Liberals and quite poor for both the Conservatives and New Democrats (losing Brandon-Souris would be a major blow to the Tories, not being in contention anywhere would be a strike against the NDP), but these polls are not without their potential problems.
First, there are the sampling issues that tend to appear in polls by Forum Research. Their IVR polls often over-sample older Canadians by a large degree, meaning that the samples of younger Canadians are smaller and thus potentially at risk of having larger errors. Those errors can then be amplified as the sample of younger voters is increased to its proper proportion.
Bourassa's sample was the least skewed, with 55% of it being over the age of 55, compared to the 40% of the voting population of the riding that is actually that old (at least according to the 2006 census, I do not believe the 2011 census has been broken down by riding just yet).
But the skew in the other ridings was significantly larger. In Provencher, 64% of the sample was 55 or older, instead of the 32% it should be. The sample in Brandon-Souris was 71% over the age of 55, when it needs to be 36%. And in Toronto Centre, the sample was 64% over the age of 55 instead of 25%.
Second, there is the issue of past voting behaviour. This is a tricky one, though, as the last election was over two years ago. Between then and now, voters have already cast a ballot in provincial elections and the population may have moved around (for example, all of the ridings report some respondents who voted Bloc in 2011, including those in Manitoba and Ontario). So, there is a natural amount of error that could occur.
Nevertheless, the samples do not match the voting results of 2011 very closely. For example, the sample in Toronto Centre reported a past vote of 51% for the Liberals, 24% for the Conservatives, and 18% for the New Democrats, instead of the actual result of 41% for the Liberals, 30% for the NDP, and 23% for the Tories. The samples are similarly Liberal in the other three ridings, while the NDP has been potentially under-estimated in Bourassa and Brandon-Souris. The Conservatives have been potentially under-estimated in the two Manitoba ridings.
If we weigh Forum's poll by how respondents said they voted in 2011, we get the following results:
Bourassa: 45% LPC, 22% NDP, 14% BQ, 11% GPC, 7% CPC
Brandon-Souris: 42% CPC, 35% LPC, 12% NDP, 11% GPC
Provencher: 60% CPC, 26% LPC, 9% NDP, 5% GPC
Toronto Centre: 40% LPC, 34% NDP, 18% CPC, 8% GPC
This still gives the Liberals a lead in Bourassa and Toronto Centre, but Brandon-Souris swings over to the Conservatives. The gap widens in Provencher, while it shrinks in both Bourassa and Toronto Centre, with the latter being particularly close. However, it should be emphasized that weighing by past vote is not necessarily more accurate than Forum's overall numbers. We don't know, for instance, whether past vote is already part of their weighting scheme (my calculations may not be taking into account other weighting factors like age or gender).
What we can know
The Ontario by-elections in August demonstrated that by-election polling can be particularly hit-or-miss. The polls called the race rather well in Etobicoke-Lakeshore and Scarborough-Guildwood, for example, but missed by a significant degree in London West and Ottawa South. The polls in Windsor-Tecumseh, while picking the winner, were off in the details. That is not an especially strong record. If it persists, two of these four by-elections will be called incorrectly by the polls.
To take this into account, I've calculated some reasonable confidence intervals we can apply to the polls in these by-elections, based on how the polls performed in the Ontario and federal by-elections of 2012 and 2013, as well as the Westside-Kelowna by-election in British Columbia earlier this year.
The margin of error of polls always includes 95% confidence, implying that 19 times out of 20 the results are within the margin of error. In other words, there is a 20 to 1 shot that the polls will be right. But that is an assessment of how accurate the polls are of the general population. We cannot know for certain whether the polls are accurately depicting the voting intentions of the general population, since the entire population does not vote. In reality, recent by-election polls have been within their margin of error only about two-thirds of the time. That gives them a roughly 2 to 1 shot of being correct.
I will be averaging the by-election polls again as I did for the Ontario by-elections, but I will be applying 67% and 95% confidence intervals to the results. Put simply, those ranges reflect the degree of error that 67% and 95% of polling results had in recent by-elections. They should act as a good guide for what to expect on voting day, based on what the polls are saying.
Here the those ranges, applied to this series of Forum polls (the polls in Bourassa and Toronto Centre from the spring are too old to be included in the weighted averages, so the weighted averages are the same as the Forum polls across the board). You can click on these charts to magnify them.
The starting positions have been established as the by-elections kick-off. The Liberals look secure enough in Bourassa, but we will need to see what happens to Laraque's support. The party also has the advantage in Toronto Centre, though the campaign is far from over. The Conservatives will need to work to hold on to Brandon-Souris, while Provencher looks safe. These four by-elections should be interesting.
21 comments:
Keep in mind that in a by-election turnout and enthusiasm will matter even more than in a general election. It wouldn't surprise me if on election day the voters skew older and Liberal.ReplyDelete
- Anonymous21 October, 2013 12:40
I live in Brandon-Souris. If FORUMS numbers skew "older" then the fact Liberal Rolf Dinsdale is leading is beyond remarkable. Older, here, means staunchly Conservative. Added to that is Brandon, Manitoba's second largest city, is also in what can be considered prairie bible belt country. Guys like Rolf - a former punk rocker with decidedly progressive ideas and attitude don't fly too well.ReplyDelete
I really hope the numbers are indicative of the vote as he would be a refreshing addition to parliament - versus the Con candidate, Maquire - an old, tire current MLA who actually lost this riding the last time he ran - when the Cons and Reform spilt the rightwing vote.
I'm going to be a a strategic voter. Rolf has my vote. And even though Harper has made it as difficult (weather wise) as he could - I'll be going out at the end of November on the prairies to cast my ABC vote.Replies
That the sample skews older does not mean that the poll skews older - that 71% of the sample over the age of 55 would have likely been re-weighted so that it represents the 36% it should. The problem isn't that the poll skews older, it is that fewer people would have been polled under the age of 55 than there should have been, meaning there is more potential for error.Delete
The 29% of the sample under the age of 55 had to be inflated to 64% of the weighted sample to get the proportions right, meaning any errors in the smaller sample of younger voters would be amplified when the sample is re-weighted.
Wikipedia has results for Brandon riding going back to 1953. In all that time, someone other than a PC or a Conservative has won once (in 1993), and the combined vote of the PC's and Reform/Alliance parties has been below 50% once (in 1988). The Conservatives losing there would be a huge upset. (Ironically, the Conservative MP from 1953 to 1980 was a Mr. Dinsdale.)Delete
- Anonymous21 October, 2013 22:59
The Dinsdale you speak of was Walter Dinsdale - the current LIBERAL candidate, Rolf Dinsdale's, father.Delete
Rolf's grandfather also served as the city's mayor and MLA.
His mother, even after marrying Walter, remained a solid Liberal supporter.
Things can change though Michael. What was the NDP's track record in Outremont before Mulcair ran there? We'll see how this goes in Brandon.Delete
Hi Eric. Did you notice this Probe Poll, for the Winnipeg Free Press. http://tinyurl.com/m439j56ReplyDelete
You mentioned comparing to the 2006 census for demographics. That you're now looking at 7 year old data, have you considered modeling population changes since then?ReplyDelete
Something along the lines of 1/n of the voters in an age bracket being bumped to the next age bracket every year (where n is the age cohort's span in years).
I don't know how much age factors into your model, but at least for conversations sake we wouldn't be comparing apples and... Well, a related albeit different sort of apple.Replies
Age doesn't factor into my model, I was referring to the representativeness of Forum's sample. While it is almost certain that the proportion of voters over the age of 55 would have increased in each riding since 2006, the difference would not be enough to get the sample into line.Delete
I wouldn't worry too much about where the George Laraque votes will end up going in Bourassa, A big proportion of people who were going to vote for him were doing so because of his star power among the Haitian voters of the riding. Not really because he was a Green. The Liberal brand there is strong due to Denis Coderre's lasting positive impression among visible minorities.ReplyDelete
Gonna have a tough time for anybody to beat that Nenshi win in Calgary !! 74% of the vote !! WOW !!ReplyDeleteReplies
Historically, 74% is actually quite a low number for a sitting Calgary mayor. I recall when I lived there Al Duerr was re-elected with 93% of the vote.Delete
Actually his last kick at the can Duerr got 73% of the vote. Duerr was pretty special though.Delete
I wouldn't call 74% low just because some elections were higher. Some were lower too. Call it par IMHO.
Dunno what it is about Alberta politics and incumbents lol.
Yeah but Ryan Nenshi ain't a Tory hence ??Delete
True. First Muslim mayor of a majority city in North America too.Delete
Though I'd point out that the previous mayor was also a Liberal.Delete
I think your point re Muslim is really the important one !!Delete
Ah.... Nenshi has never indicated what party federal or provincial he supports!Delete
He has been courted by all three parties but, his former chief of staff does have links to the Alberta party which is decidedly centrist even small "c" conservative!
Nenshi could well be a Tory at heart since he has not commented on the subject we don't know and Peter's comment; "ain't a Tory" is at best speculation and at worse incorrect.
I wonder if this will change the numbers in Toronto Centre;ReplyDelete
I wonder how much the Duffy attack of yesterday will change the numbers ?ReplyDelete
BTW Eric, on the "where will Laraque's votes go" question, keep in mind that Dubourg and him are from the same community group.ReplyDelete
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Reports: Shark Attacks Kayak Near Plymouth
A great white shark bit into a kayak off the coast of Plymouth Wednesday night, according to several reports. Two kayakers ended up in the water but were not hurt in the exchange, according to Plymouth's harbormaster.
According to NECN, the Massachusetts Environmental Police said the attack likely came from a great white shark. The Plymouth-based Manomet Current reported that a Massachusetts State Police helicopter was called in to search for the shark. The attack was preceded by an earlier shark sighting. In that case, a kayaker reported seeing a shark attack and kill a seal, according to the Current.
The apparent attack comes after a week after Duxbury briefly shut its public beaches when a great white was spotted nearby. Two similar incidents in Duxbury and Marshfield turned out to be false sighting. Spotters had mistaken the fin of a sunfish for that of a shark. A shark was also spotted in the Taunton River, which has had its share of exotic visitors this year.


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Aaron Greenberg
Xbox bringing "a lot of surprises" to E3
Xbox fans have a lot to look forward to at this year's E3, apparently.
Aaron Greenberg headlines
Microsoft debunks cheaper Xbox One rumour: "don't believe everything you read"
Xbox One rumours were ten-a-penny last week, thanks to an anonymous tipster who is apparently now being pursued legally by Microsoft. One such claim was that the company is preparing to unveil a new, cheaper Xbox One model or price-cut on the existing model. Chief of Staff Aaron Greenberg has debunked the rumours.
Xbox One developers won't be forced to shoot for 1080p, says exec
Microsoft won't make 1080p a mandatory goal on the Xbox One platform, according to chief of staff for company's devices and studios group Aaron Greenberg. It follows some chaos after Ryse was confirmed to run natively at 900p.
GameStop halted Xbox One pre-orders because demand was too high - Microsoft
It appears GameStop stopped taking pre-orders for Xbox One because the demand was too high.
Xbox One: E3 showing 'will get it right', says Greenberg
Xbox One's games will be the main focus of Microsoft's pre-E3 conference this year, and chief of staff for interactive entertainment Aaron Greenberg has addressed several fan concerns on Twitter, stating that the show will get it right, that Microsoft loves indies and that many current fears are based on assumptions.
Xbox One: Greenberg reiterates "main focus," to be on games at E3 2013
Microsoft's Aaron Greenberg has reiterated to expect more on not only Xbox One at E3, but a major focus on the games.
Microsoft to announce "tons of exclusives" at E3 next month
Microsoft is set to unveil its new Xbox console next week, but it is apparently saving some of its big software announcements for E3 as the console reveal is serving as foundation laying so to speak.
Xbox 720 reveal: Microsoft staff tweet pictures of venue's creation
Microsoft is gearing up to unveil its Xbox successor on May 21, and is currently building a venue for the big day. Chief of staff for interactive entertainment business Aaron Greenberg and Larry 'Major Nelson' Hyrb have been tweeting photos of the venue's creation.
Kinect: There "won't be a correlation" between game reviews and sales, says Greenberg
Aaron Greenberg is a confident man. So confident, he believes Kinect will sell more units at launch than the Wii did. He is also so confident in Kinect, he doesn't think reviews of games created for it will affect sales of the device or the games created for it in any way.
Kinect will sell more units than Wii at launch, says Greenberg
Microsoft's Aaron Greenberg is confident Kinect will sell. The man thinks it'll sell more then Wii did at its launch four years ago, after all.
Greenberg: "Kinect is more about the games than the tech"
Aaron Greenberg has said the games shown at TGS this week for Kinect are just the second wave of titles for the new tech, and there's a lot more out there waiting in the wings.
Tsunoda - Kinect will "blow away" iPad sales
Kinect creative chief Kudo Tsunoda reckons the 360 motion camera's going to put Apple's iPad in the shade. It'll probably take it to school as well.
Kinect will sell 3 million units this Christmas, says Greenberg
Microsoft's Aaron Greenberg has told Gama the company expects to sell 3 million units of Kinect this Christmas.
Greenberg: Xbox 360 sales up 88%, lead console in June
Microsoft's Aaron Greenberg has said on Twitter Xbox 360 sales are up 88 percent post E3, and Xbox 360 was the top selling console in June.
Braben: Kinectimals does not use Milo & Kate tech
Frontier has said its feline-filled Kinectimals does not use any technology based on Lionhead's Milo & Kate, despite comments made earlier in the week by Microsoft.
Molyneux on Milo technology: it "actually does work"
Lionhead boss Peter Molyneux has told attendees at GameHorizon in Newcastle that Milo & Kate is still on the way from the studio.
Microsoft's Greenberg: Milo "absolutely" still in development
Microsoft's Aaron Greenberg has confirmed that Milo & Kate is still in development and is merely a product not slated for release this Holiday, despite earlier reports claiming the Kinect title would never ship.
Xbox boss questions "consumer demand" for 3D
Sony may have bet big on 3D during its E3 press conference, but Xbox production boss Aaron Greenberg has questioned the readiness of the market for the technology, saying Microsoft is to take "pull than a push approach" to 3D and will wait "until the market responds".
Interview - Microsoft's Aaron Greenberg
Aaron Greenberg is not the man you expect him to be. Once famed for his tirades against 360's competition, Xbox's director of product management is not actually green. He is, in fact, very pleasant. He smiles; he laughs; he exudes a relaxed air you wouldn't have naturally associated with an integral player in Microsoft's E3 […]
Greenberg: Hardcore gamers are still MS's focus
Microsoft's Aaron Greenberg has said that hardcore gamers will not be forgotten now that Kinect is here.
Page 1
Aaron Greenberg latest
Microsoft debunks cheaper Xbox One rumour: "don't believe everything you read"
Xbox One developers won't be forced to shoot for 1080p, says exec
GameStop halted Xbox One pre-orders because demand was too high – Microsoft
Xbox One: Greenberg reiterates "main focus," to be on games at E3 2013
Xbox 720 reveal: Microsoft staff tweet pictures of venue's creation
Kinect: There "won't be a correlation" between game reviews and sales, says Greenberg
Kinect will sell more units than Wii at launch, says Greenberg
Kinect will sell 3 million units this Christmas, says Greenberg
Microsoft's Greenberg: Milo "absolutely" still in development
Sony UK boss says he's "not too fussed" about comments from competitors
Greenberg: Natal E3 "experience" will demonstrate 360's "universal appeal"
Microsoft to hold E3 press conference plus Natal "experience" event [Update]


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In Praise of Vacant Lots
It's easy to talk about the importance of the commons in grand terms—vast stretches of breathtaking wilderness, publicly funded advances in science and technology, essential cultural and civic institutions, the air and water which we all depend on for survival.
But let's not forget the lowly commons all around that enliven and enrich our lives. Things like sidewalks, playgrounds, community gardens, murals, neighborhood hang-outs, and vacant lots. Especially vacant lots.
Modern society's obsession with efficiency, productivity and purposefulness sometimes blind us to the epic possibilities of empty spaces that aren't serving any profitable economic function. The word "vacant" itself implies that these places are devoid of value.
But think back to all the imaginative uses you could discover for vacant land as a kid. In my neighborhood we squeezed a baseball diamond, 6-hole golf course, horseshoe pit and vegetable garden (right behind the third base line) into the lot behind my house. My dad mowed the expanse of weeds every week, but it belonged to every kid in the neighborhood. All summer long, we'd gather there after breakfast to plot our adventures for the day.
In the back of my mind I always knew that someone else owned the land and that some sad day a house would rise where we swung five-irons on bumpy fairways and picked ripe cantaloupes, but I am so grateful it was ours for a while.
Thankfully, in many places today commoners are working to make sure that vacant lots can delight successive generations of kids.
Jonathan Rowe, who wrote with keen insight and love about the commons until his death last year, became a champion of shared public space in his town, Point Reyes, California, where several vacant lots on Main Street serve as social hubs for the community.
Rowe and his colleague Elizabeth Barnet of the West Marin Commons highlighted the importance of these privately owned spaces, and the threat that one day they may disappear from the public realm. Just a few months before his death, the group secured a long-term lease for land at the corner of Main and 4th, which is now commonly called Jon Rowe Park.
Even more ambitious is the 596 Acres project , which identified in every last parcel of publicly owned vacant land in Brooklyn with an eye to opening them up to the community for gardens and informal parks. The project is now expanding across the city, and the 596 acres website offers detailed information on how to begin the process of turning vacant lots (including those now locked behind fences or privately owned) into community commons.
Welcome to a new kind of movement—one that reshapes how we think about ownership and cooperation.
Just because someone doesn't bike, doesn't mean they can't benefit from cities and towns making biking a priority.
How our communities can stop losing out on business and tax revenue.


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Inevitably, a tragedy such as what we have experienced in Newtown, Connecticut brings the discussion about guns and violence in our society to the front of the American dialogue where it often lingers for a short time before receding to the background of the national discussion.
Will our response to this latest horror be any different?
While many believe that the chord touched by this unspeakable event will reach equally into the hearts of both the most ardent supporter of the right to bear arms and those who oppose guns—thereby prompting all sides to come to an understanding that something has to change—will this really prove to be the moment or will this tragedy just fade away as the many that have come before it have been allowed to go without response—if a response is even possible?
Certainly, there appears to be a special pain that comes with the stark realization that these 20 small children remind us all of our own kids, grandchildren, sisters and brothers. Those lost at Sandy Hook Elementary School looked and behaved just like our own children look and behave. They were in a place they were supposed to be—having been sent there by parents who did just as we have all done so many times when we buttoned up our kids' winter coats and sent them off to school for the day. Because of this, we feel like we "know" these people better than those involved in similar tragedies in our past and because we feel that we can relate to those so grievously affected, we instinctively know that if ever there was an instance of "There, but for the grace of God, go I.", this is surely it.
Still, if we are to hope for something to happen that might bear some positive impact on preventing these now all too frequent attacks, it has to begin with the two sides of this discussion moving towards a better understanding of what the other believes—just as it must involve a recognition that this is not just about the guns.
People who would very much like to see combat style weapons and high capacity ammunition magazines disappear from the landscape—people like me—must begin by accepting and internalizing the simple fact that those who support wide access to guns, including semi-automatic weapons, are feeling the very same grief today that is being experienced by anti-gun advocates.
Supporting gun ownership does not make one a cold and unfeeling human being who puts their interest in weapons above their interest in humanity.
Indeed, it is often quite the opposite. Avid defenders of the Second Amendment right to bear arms believe that it is precisely because of their desire to protect their own children that they take a strong, pro-gun position. It is, after all, difficult to argue with the suggestion that the evil and the confused will almost always find a way to get their hands on their weapon of choice and that the only corresponding choice one might have in the effort to defend against this reality is to fight "fire with fire." As these folks are quick to point out, had more of the adults working at the Sandy Hook Elementary School been armed, just maybe this would have had a better ending.
Maybe. But we must also recognize that had the magazine clip been limited to fewer bullets, the odds of an adult being able to take this murderer to the ground before he could take more lives would also have been greatly increased.
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And while many of us cannot quite understand the strong feelings of those who believe that ownership of combat style weapons is not only appropriate but is a necessary extension of an individual's right to defend their household against enemies—foreign and domestic—our lack of understanding does not negate such an individual's profound right to believe that this is a necessity.
While anti-gun advocates correctly note that these horrible events do not happen—or happen with dramatically less frequency—in other nations where guns are harder to access, we must acknowledge the pro-gun perspective noting that citizens in these other countries are left defenseless should their own government, or some other government, ever seek to turn against those citizens.
No matter how staunch and defined your feelings may be when it comes to regulating guns, or your desire to see these weapons disappear altogether from our society, somewhere in the back of your mind you must recognize that those who are passionate in their support of gun ownership do possess a few points—grounded in both logic and law—that support their position. If we are to find common ground and a way forward in addressing horrible events such as what transpired on Friday, we are going to need to bring these points to the forefront of our understanding.
At the same time, those who view relatively unlimited gun ownership as an essential and non-assailable right granted to us all in the Bill of Rights must begin to better understand and appreciate why anti-gun advocates simply cannot see the sense and logic behind making combat style weapons and high capacity magazine clips available to civilian purchasers.
These folks must appreciate that, to the anti-gun advocate, the notion that you must own combat style weapons to stand up against the potential tyranny of your own government, or another's, fails when one considers the overwhelming power government would bring against you should this ever become government's intent. Thus, your ability to possess such combat style firearms, magazine clips, etc., becomes largely symbolic and, to the extent that your easy access to this type of weapon facilitates access for those who should never get them, the trade off just doesn't make a lot of sense.
Pro-gun proponents must also come to an understanding that our Second Amendment rights can be protected without being twisted in a way that perverts any rational understanding of that right. As many have heard over these past few days, we have long recognized that there are limits to our enumerated rights —limits based on what is required for a society to function.
We know that nobody has a First Amendment right to scream 'fire' in a crowded theater when there is no such fire. Why? Because the Supreme Court wisely understood that the Founders, in codifying these important rights, never intended them to be used to bring harm to the people in that theater when someone stupidly decides that it would be amusing or meet some perverse objective by causing a panic.
In similar fashion, while our Founders did intend for Americans to have a right to defend their households from attack by possessing firearms, nobody should rationally arrive at the conclusion that the rights provided by our Second Amendment were ever intended to grant the right to bear arms for the purpose of opening fire in the same crowded theater when our First Amendment right has been limited to falsely vocalize the word 'fire'.
(Continued on next page)
While anti-gun advocates can—and should—respect the rights and beliefs of those who see gun ownership as important in the defense of the lives they feel responsible to defend—including their own—those who support gun ownership need to step up and appreciate that it may now be necessary to make some sacrifices to their unfettered right to protect their own children in order to help someone else protect theirs. They need to contemplate whether or not they really want a society where schoolteachers are to be armed with semi-automatic weapons. While one can conclude that this is one possible way to go, the question must be asked as to whether it is the best possible approach—particularly when we haven't even tried going at this in a way that takes the nation down the more desirable path of not becoming one big armed encampment.
And while reasonable people accept that there is likely no way to get rid of guns, is there not a way to control the volume of ammunition that is fed into the guns that can do so much damage?
But it is not just the guns.
For many years, I have taken the side of believing that those who criticize violence in video games or gratuitous violence in motion pictures and television were overstating the impact of these entertainment forms when it comes to the carrying out of violence in real life. In defense of the same, I would often point out how, when I was a kid, I would watch "Road Runner" cartoons—laughing hysterically when Wile E. Cayote would get an avil dropped on his head. And yet, viewing these programs never inspired me to want to drop an anvil on anyone or do violence as it was done in these classic animations.
For me, that is over.
It would be completely unreasonable on my part to push for legislation attempting to make it more difficult for people to get their hands on combat style weapons and high capacity ammunition magazines while continuing to defend violence as a part of free expression in entertainment.
At the end of the day, none of this is about responsible people owning guns nor is it about how well-adjusted people are capable of reacting to fantasy violence in entertainment.
Rather, it is all about how those who are suffering from mental conditions that allow them to conclude that carrying out these unspeakable acts are, somehow, what they are meant to do and how these people are impacted by violent entertainment and the weapons that allow their delusions to become reality.
In order for a society to advance, all things must be always be subject to change.
If that means that Hollywood producers and video game programmers must give up a few bucks in profits for the chance that even one Sandy Hook experience looming in our future can be avoided, that price should willingly be paid. And if making it impossible for ammunition and high capacity magazines to be purchased on the Internet while bringing back an assault weapons ban—this time with real teeth and designed to truly make it more difficult for combat style weapons to fall into the hands of those who truly should not have them—means saving the life of someone else's child, then that is what we have to do.
There are other questions that we can address.
We can ask why, for some, it is easier to access semi-automatic weapons and high volume magazine clips than it is to access high-quality mental health care. We can ask if there is a better way to address the needs of the mentally ill to protect both the afflicted and society. We can ask if there is adequate education for the parents of children with mental challenges to help them deal with the nightmare of knowing that their child could be at risk for this type of behavior.
And we can ask if our Second Amendment rights really demand that high volume magazine clips—something we find involved in virtually every one of these terrible incidents—is really critical to the protection of our liberties.
But nothing happens if nobody is willing to understand what the other side is thinking...and why. Compromise in the name of progress is impossible when neither side can hear what the other is trying to say or when each side begins with the belief that the other is either morally deficient or wildly unrealistic.
If anti-gun advocates want to see something done to improve this situation, stop vilifying those who see it differently. And if you identify as 'pro' gun, start thinking about how your efforts to defend your own perspective may be standing in the way of finding an answer to the problem.
Maybe there is nothing we can do to stop these unspeakable tragedies from happening—but not even trying seems a truly ridiculous option.
contact Rick at email@example.com and follow me on Twitter @rickungar and Facebook.


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Trade News
Munich, Germany, 12 May, 2010 – Linde Gases, a division of The Linde Group, today announced the launch of its ARCLINE® Cleanflow gas purging system which allows purge time of pipes to be reduced by up to 45 percent, significantly improving welding productivity. The innovative patent-pending system produces a unique gas flow resulting in a near instantaneous removal of oxygen and allowing welding to commence almost immediately.
The new system not only prevents oxidation, but also staining caused by metal vapour that can appear at the sides of the welds, leaving them pristine in appearance and free from contaminants and alleviating the need for costly post weld cleaning. In addition, the special gas flow also has a cooling effect which reduces post weld waiting time and allows further processing of the pipes to start more quickly. The new purging system is particularly well suited to industries where the highest levels of cleanliness and zero tolerance of oxidation and staining levels are imposed, including the pharmaceutical, food and beverage and nuclear industries.
"Linde has always played a pioneering role in gas technology within the welding market," said Lee Hermitage, Global Marketing Manager, Manufacturing Industry, Linde. "The development of the ARCLINE® Cleanflow purging system is further verification of not only our continuing commitment to innovation, but to providing products and solutions which significantly improve our customers' productivity and help their compliance to safety and quality requirements."
About The Linde Group
The Linde Gases Division, part of the Linde Group, is a leader in the international industrial and healthcare gases markets, providing compressed, bulk, specialty and medical gases, as well as chemicals to virtually all fields of industry globally. The company adds value to its customers' businesses through the provision of state-of-the-art application technology, process know-how, services and equipment.
The Linde Group is a world leading gases and engineering company with almost 48,000 employees working in more than 100 countries worldwide. In the 2009 financial year it achieved sales of EUR 11.2 billion. The strategy of The Linde Group is geared towards sustainable earnings-based growth and focuses on the expansion of its international business with forward-looking products and services.
Linde acts responsibly towards its shareholders, business partners, employees, society and the environment – in every one of its business areas, regions and locations across the globe. Linde is committed to technologies and products that unite the goals of customer value and sustainable development.
For more information, see The Linde Group online at http://www.linde.com
Susan Brownlow
Public Relations Manager
Mobile: +44 (0)7825 853814
E-Mail: email@example.com


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Skip to Content
Home > Health Information > Health Library > Juvenile Idiopathic Arthritis: Serial Casting
Some children who have developed mild to moderate
contractures (knees, ankles, wrists, fingers, elbows)
may benefit from serial casting.
Serial casting is a temporary straightening and casting of the
affected joint (for about 2 days). The cast is then removed, the child goes
through some physical therapy, and a new cast is applied with the joint
stretched a bit more.
The procedure is repeated with the joint a little straighter each
time. This process continues until maximal straightening has occurred. A
resting splint may be worn at night for 3 to 6 months afterwards.
Serial casting may be able to restore the ability to straighten a
mildly contracted joint, but it is unlikely to improve severe
Current as of: April 1, 2019
Author: Healthwise StaffMedical Review: Susan C. Kim, MD - PediatricsMartin J. Gabica, MD - Family MedicineKathleen Romito, MD - Family MedicineJohn Pope, MD - Pediatrics
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Current as of:
April 1, 2019
Healthwise Staff
Medical Review:Susan C. Kim, MD - Pediatrics & Martin J. Gabica, MD - Family Medicine & Kathleen Romito, MD - Family Medicine & John Pope, MD - Pediatrics
This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use and Privacy Policy. Learn how we develop our content.
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mobilitynow necesitaba un nuevo diseño de logotipo y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 974 diseños de 222 diseñadores freelance.
MobilityNow is an initiative recently launched by HTC America (http://www.htc.com/us) to address the mobility needs of large enterprises. Our charter is to provide value-added services that help motivate the adoption of smartphones within Fortune 500 organizations.
Our vision is focused on helping organizations achieve business success through mobility solutions. MobilityNow's deep expertise in smartphone hardware and thorough understanding of the mobility marketplace, ensures that we can provide maximum value at every stage in an organization's mobility expansion and development.
Fortune 500 technical and wireless decision-makers.
- Technically savvy
- Looking for solutions to business problems
Deliverable - primary logo for mobilitynow
We are very open-minded and looking for innovative concepts. Here are some things that we regard as positive attributes for the design:
- creative & unique, something that stands out
- Brand Attributes: premium, stylish, Innovative, empowerment; smart
- easily relates to our Fortune 500 customers
Feel free to experiment with colors, graphics and type (i.e. MobilityNow, mobilityNOW, MobilityNow!, etc.), but please keep the design clean and simple.
Here are examples of logos that reflect the qualities we want to project:
- http://www.mobilitynow.com/logosamples.htm
The files we will require are:
- Print file format - .ai (CMYK)
- Web file format - .jpg and layered .psd (RGB)
Please do not use stock images or clip art in the logo, and only use work that can be fully transferred to us upon winning the contest.
Descubre cómo funciona un concurso de diseño u obtén más información sobre nuestros servicios de diseño de logo.


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Tired of opinions in your game reviews? Hanging out for something that's truly objective that'll just give you the facts while you make your purchasing decision/forum debate? Objective Game Reviews is the site for you.
No longer do you need to suffer through one reviewer's personal experiences, or their attempts to critique a game as though it were some kind of *gasp* artform.
At Objective Game Reviews - it's a joke site, guys - you're getting the facts and a score, just like you've always wanted. Enjoy!
(I've seen some people say this site is a critique of reviews. Maaayybe, but I think the name gives away that it's really about those who think a review can somehow be objective at all.)
Objective Game Reviews [Site]


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Avian influenza – situation in Viet Nam – update
8 February 2012 - The Ministry of Health (MoH) has announced a confirmed case of human infection with avian influenza A (H5N1) virus.
The case was a 26 year-old pregnant female from Soc Trang province. She developed symptoms on 23 January 2012, and was admitted to hospital on 25 January. She was treated with Oseltamivir on 27 January, she died on 28 January. Confirmatory test results for influenza A (H5N1) were obtained on 30 January by Pasteur Institute, the WHO National Influenza Centre in Ho Chi Minh City, Viet Nam. Samples from the newborn infant of the fatal case tested negative for H5N1.
The case had slaughtered and eaten sick chickens. MoH, the local health sector and Pasteur Institute in Ho Chi Minh City are conducting epidemiological investigation and strengthening surveillance and response activities. Close contacts of the fatal case have received prophylaxis and are being monitored; to date all remain well. The Department of Animal Health is collaborating with the human health sector.
The case is the 121st person in Viet Nam to become infected with the H5N1 virus. To date, 61 of these cases have died from complications of the disease.


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The research report " International Healthy Snacks Market Analysis Report 2019" furnishes business and technology analysis, and tactical prophesy for Healthy Snacks market, scaling the market with the help of product kind, end-use sector, and geography. The report delivers former data previous year data along with today's market evaluations for Healthy Snacks, and prediction to 2027. The report is the pivotal designing tool for Healthy Snacks businesses, you can recognize commercial enterprise possibilities using approximative market predictions and apply a complete dissection of market sizes to furnish upcoming master plans with judgment.
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Just when you thought it was safe to go back on the internets, seems like the ghost of SOPA's still lingering about. Bertena Varney published a highly disturbing article today: 'Universal Studios claim Dracula fan's Facebook page'. What. The. Hell?!
The owner of the page is—full disclosure—a friend of mine, Charles E. Butler. He wrote The romance of Dracula: a personal journey of the Count on celluloid (2011). The article reveals that on January 20th, Facebook sent him the following message:
You may have noticed that you're no longer an admin of one of the Facebook Pages you used to manage. The Page was claimed by someone who proved that they're authorized to represent it.
The Facebook Team
Proof is the key here, because even though Universal made the first (official)1 Dracula movies after negotiations with Bram Stoker's widow, Florence Balcombe Stoker, they do not own Stoker's work or derivatives from it—unless, of course, it exploits their Dracula franchise, namely Dracula (1931), Dracula's daughter (1936), Abbot and Costello meet Frankenstein (1948), etc.
As respected Dracula scholar, David J. Skal notes, 'due to a loophole in copyright law, Dracula was – and always had been – in the public domain in the United States. Although Stoker had been issued a copyright certificate in 1897, and his widow a renewed certificate in the 1920s, Stoker had never complied with the requirement that two copies of the work be deposited with the American copyright office.'2 Therefore, Universal simply has no right to claim 'Dracula' from someone else.
Add your signature to a petition asking Universal to give Butler's page back. I've signed it; hope you do, too. Stand up for the 'little guy'!
1. F.W. Murnau's well-known Nosferatu, eine Symphonie des Grauens (1922) was an unauthorised rip-off.↩
2. DJ Skal, Hollywood gothic: the tangled web of Dracula from novel to stage to screen, W.W. Norton & Company, New York, 1990, p. 180.↩


text:
Kyodo News via AP
People pack the central intersection of Tokyo's Ginza shopping district as Japanese Olympic medalists and athletes who competed in the London Games aboard double-decker buses parade through the main street Monday, Aug. 20.
Jiji Press / AFP - Getty Images
Japan's women's badminton doubles silver medallists Mizuki Fujii, left, and Reika Kakiiwa, wave to the crowds from an open-top bus during a parade for Japan's 2012 London Olympic Games medallists in Tokyo's Ginza shopping district on Aug. 20.
The Japan Olympic Committee (JOC) held the first ever Olympic medallists parade hoping it will boost the city's bid to host the 2020 Summer Games.
Reuters reports: Japan's Olympic medallists brought downtown Tokyo to a standstill on Monday in an open-top bus victory parade witnessed by around 500,000 flag and fan-waving supporters.
The convoy of five buses caused gridlock as fans and shoppers in Tokyo's upmarket Ginza district help celebrate Japan's record haul of 38 medals (seven gold, 14 silver and 17 bronze) at the London Olympics. Full story.


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Ivory Coast's Megalomaniacs: Quattara And Gbagbo
Gbagbo is a supreme Machiavellian. He was willing to die or be captured. He knows Abidjan is hostile territory for Quattara and he has painted his rival as a stooge of the West installed by Imperial France.
[Black Star News Editorial]
Alassane Quattara has scored a pyrrhic victory in the Ivory Coast. He could be a big loser in the end unless he can invite Laurent Gbagbo's supporters into the political tent very quickly.
Assisted by the United Nations and Imperial France, Quattara routed his political rival Gbagbo and rousted him from his basement hideout. Yet, beware, why was Gbagbo willing to risk his life at the very end? Mad man or Machiavellian schemer?
Gbagbo's ending was not a good beginning for Quattara's presidency--it undermines it and might eventually bring it down.
Quattara has ordered an "investigation" into Gbagbo's actions. What charges might be brought against him? Crimes against humanity for the massacres of civilians? What about the several hundreds murdered by Quattara's fighters? Who will bring charges against Quattara?
Both men claimed victory in November's presidential election runoff. Several countries, including the United States, France and Britain recognized Quattara, a former IMF man and once prime minister under autocrat Houphet Boigny. The United Nations, African Union and Ecowas endorsed him. African heads of state shuttled back and forth trying to get Gbagbo to step down. A stalemate lasted for months. Human rights organizations documented atrocities against civilian supporters of Quattara by Gbagbo's armed forces.
Eventually guerrillas allied with Quattara broke a ceasefire that had spilt the country in half for 10 years and marched on Abidjan, the commercial capital. According to the UN and Human Rights Watch: the Quattara fighters massacred several hundreds of Gbagbo supporters; they burned people alive in their homes; and, they committed mass rapes. Gbagbo's forces also massacred hundreds, these organizations say.
Both Gbagbo and Quattara should actually be prosecuted by the International Criminal Court (ICC); yet, the court is so corrupt under Prosecutor Luis Moreno Ocampo, so partisan and so abused by the Western powers that it might protect Quattara and indict only Gbagbo.
Why was Gbagbo willing to die or be captured? He knows Abidjan is hostile territory for Quattara and he has painted his rival as a stooge of the West installed by Imperial France and the much hated Nicolas Sarkozy.
It's hard to imagine that it won't be only a matter of time before Abidjan turns hostile on Quattara unless there is a broad and inclusive government. So, even in "defeat" Gbagbo was actually still bargaining.
Without an accomodation with supporters of his foe Gbagbo, the Quattara presidency will be on shaky grounds. He would have to resort to imposing his regime in the same manner in which he finally gained power--with French and United Nations guns.
Gbagbo knows this. Quattara knows this.
As these two megalomaniacs dueled, the biggest losers were the ordinary people of the Ivory Coast.
"Speaking Truth To Empower."
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- Ann GarrisonFebruary 22,2018 @ 08:03 PM
I think you have "Filtered HTML" turned on here. If you switch to "Full HTML," it will probably...
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text:
As if Zooborns and Cute Overload and didn't do enough to encourage inappropriate pet acquisition, check out this slow motion chipmunk rubbing its little face with its tiny little paws. I want to buy it a pair of overalls.
And to think that right now that adorable furry little guy can't think about anything but nuts.
Slow Motion Chipmunk [Buzzfeed]