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Diabetes mellitus is a condition in which the body does not produce enough of the hormone insulin, resulting in high levels of sugar in the bloodstream. There are many different types of diabetes; the most common are type 1 and type 2 diabetes, which are covered in this article. Gestational diabetes occurs during the second half of pregnancy and is covered in a separate article. Diabetes can also be caused by disease or damage to the pancreas, Cushing's syndrome, acromegaly and there are also some rare genetic forms.
When there is excess glucose present in the blood, as with type 2 diabetes, the kidneys react by flushing it out of the blood and into the urine. This results in more urine production and the need to urinate more frequently, as well as an increased risk of urinary tract infections (UTIs) in men and women. People with type 2 diabetes are twice as likely to get a UTI as people without the disease, and the risk is higher in women than in men.
10. Importance of keeping appointments and staying in touch with a health care provider for consultation and assessment. Periodic evaluation of the binding of glucose to hemoglobin (glycosylated hemoglobin or hemoglobin A1C testing) can give information about the effectiveness of the prescribed regimen and whether any changes need to be made. The ADA position statement on tests of glycemia in diabetes recommends routine testing for all patients with diabetes. It should be a part of the initial assessment of the patient, with subsequent measurements every three months to determine if the patient's metabolic control has been reached and maintained.
Type 2 diabetes typically starts with insulin resistance. That is, the cells of the body resist insulin's efforts to escort glucose into the cells. What causes insulin resistance? It appears to be caused by an accumulation of microscopic fat particles within muscle and liver cells.4 This fat comes mainly from the diet—chicken fat, beef fat, cheese fat, fish fat, and even vegetable fat. To try to overcome insulin resistance, the pancreas produces extra insulin. When the pancreas can no longer keep up, blood sugar rises. The combination of insulin resistance and pancreatic cell failure leads to type 2 diabetes.
By the time a person is diagnosed with type 2 diabetes, up to 50% of the beta cells in the pancreas have usually been damaged. In fact, these cells may have been declining for up to 10 years before the diagnosis. Along with raised blood pressure and elevated cholesterol levels, this predisposes the person to arterial damage years before diabetes is diagnosed. So, at the time of diagnosis, the person is already at risk for cardiovascular disease (CVD).
Maturity onset diabetes of the young (MODY) is a rare autosomal dominant inherited form of diabetes, due to one of several single-gene mutations causing defects in insulin production.[52] It is significantly less common than the three main types. The name of this disease refers to early hypotheses as to its nature. Being due to a defective gene, this disease varies in age at presentation and in severity according to the specific gene defect; thus there are at least 13 subtypes of MODY. People with MODY often can control it without using insulin.
It will surely be tough eating salads and vegetables when everyone else at your dinner table is eating pizza. Decide that this diagnosis can benefit the health of the entire family. Educate your family about the benefits of eating a healthy diet. Take your children grocery shopping with you. Practice the plate method: Aim to make half your plate non-starchy vegetables; a quarter lean protein; and a quarter whole grains or starchy vegetables, like sweet potatoes. Make exercise part of your daily routine and include your family. Go for walks after dinner. Head to the pool on the weekends, or enroll in an exercise class. If you don't have children, aim to find others with diabetes or friends that can act as your workout partners.
You can develop type 2 diabetes at any age, even during childhood. However, type 2 diabetes occurs most often in middle-aged and older people. You are more likely to develop type 2 diabetes if you are age 45 or older, have a family history of diabetes, or are overweight or obese. Diabetes is more common in people who are African American, Hispanic/Latino, American Indian, Asian American, or Pacific Islander.
You may be able to manage your type 2 diabetes with healthy eating and being active, or your doctor may prescribe insulin, other injectable medications, or oral diabetes medicines to help control your blood sugar and avoid complications. You'll still need to eat healthy and be active if you take insulin or other medicines. It's also important to keep your blood pressure and cholesterol under control and get necessary screening tests.
Aspirin should be used as secondary prophylaxis in all diabetic people with evidence of macrovascular disease, and it should be strongly considered as primary prevention in diabetic subjects with other risk factors for macrovascular disease, such as hypertension, cigarette smoking, dyslipidemia, obesity, and albuminuria (macro or micro).228 Because of the platelet defects associated with diabetes, it is recommended that the dose of aspirin should be 300 mg per day,228–230 although the American Diabetes Association's position statement (http://www.diabetes.org/DiabetesCare/supplement198/s45.htm) advocates a dose of 81 to 325 mg enteric-coated aspirin per day. If the patient cannot tolerate aspirin, then clopidogrel231 can be used.
Insulin Therapy. Exogenous insulin is given to patients with diabetes mellitus as a supplement to the insufficient amount of endogenous insulin that they produce. In some cases, this must make up for an absolute lack of insulin from the pancreas. Exogenous insulin is available in various types. It must be given by injection, usually subcutaneously, and because it is a potent drug, the dosage must be measured meticulously. Commonly, regular insulin, which is a fast-acting insulin with a short span of action, is mixed with one of the longer-acting insulins and both types are administered in one injection.
The primary complications of diabetes due to damage in small blood vessels include damage to the eyes, kidneys, and nerves.[32] Damage to the eyes, known as diabetic retinopathy, is caused by damage to the blood vessels in the retina of the eye, and can result in gradual vision loss and eventual blindness.[32] Diabetes also increases the risk of having glaucoma, cataracts, and other eye problems. It is recommended that diabetics visit an eye doctor once a year.[33] Damage to the kidneys, known as diabetic nephropathy, can lead to tissue scarring, urine protein loss, and eventually chronic kidney disease, sometimes requiring dialysis or kidney transplantation.[32] Damage to the nerves of the body, known as diabetic neuropathy, is the most common complication of diabetes.[32] The symptoms can include numbness, tingling, pain, and altered pain sensation, which can lead to damage to the skin. Diabetes-related foot problems (such as diabetic foot ulcers) may occur, and can be difficult to treat, occasionally requiring amputation. Additionally, proximal diabetic neuropathy causes painful muscle atrophy and weakness.
Type 1 diabetes mellitus is a chronic metabolic syndrome defined by an inability to produce insulin, a hormone which lowers blood sugar. This leads to inappropriate hyperglycaemia (increased blood sugar levels) and deranged metabolism of carbohydrates, fats and proteins. Insulin is normally produced in the pancreas, a glandular organ involved in the production of digestive enzymes and hormones such as insulin and glucagon. These functions are carried out in the exocrine and endocrine (Islets of Langerhans) pancreas respectively.
Diabetes is a chronic condition, and it can last an entire lifetime. The goal of treating diabetes is to keep blood glucose levels as close to a normal range as possible. This prevents the symptoms of diabetes and the long-term complications of the condition. If you've been diagnosed with diabetes, your doctor – working with the members of your diabetes care team – will help you find your target blood glucose levels.
A person of Asian origin aged 35 yr or more with two or more of the above risk factors, should undergo a screening test for diabetes. An oral glucose tolerance test (OGTT) is commonly used as the screening test10. Fasting and 2 h post glucose tests can identify impaired fasting glucose (IFG) (fasting glucose >110 - <125 mg/dl), impaired glucose tolerance (IGT) (2 h glucose >140-<200 mg/dl) and presence of diabetes (fasting > 126 and 2 h glucose >200 mg/dl). If a random blood glucose value is > 150 mg/dl, further confirmation by an OGTT is warranted. Recently, glycosylated haemoglobin (HbA1c) has been recommended as the test for diagnosis of diabetes (>6.5%). Presence of pre-diabetes is indicated by HbA1c values between 5.7 - 6.4 per cent11.
Being overweight is a risk factor for developing diabetes, but other risk factors such as how much physical activity you get, family history, ethnicity, and age also play a role. Unfortunately, many people think that weight is the only risk factor for type 2 diabetes, but many people with type 2 diabetes are at a normal weight or only moderately overweight.
Previously, CGMs required frequent calibration with fingerstick glucose testing. Also their results were not accurate enough so that people always had to do a fingerstick to verify a reading on their CGM before calculating a dose of insulin (for example before meals or to correct a high blood sugar). However, recent technological advances have improved CGMs. One professional CGM can be worn for up to 14 days without calibration. Another personal CGM can be used to guide insulin dosing without confirmation by fingerstick glucose. Finally, there are now systems in which the CGM device communicates with insulin pumps to either stop delivery of insulin when blood glucose is dropping (threshold suspend), or to give daily insulin (hybrid closed loop system).
The earliest surviving work with a detailed reference to diabetes is that of Aretaeus of Cappadocia (2nd or early 3rd century CE). He described the symptoms and the course of the disease, which he attributed to the moisture and coldness, reflecting the beliefs of the "Pneumatic School". He hypothesized a correlation of diabetes with other diseases, and he discussed differential diagnosis from the snakebite which also provokes excessive thirst. His work remained unknown in the West until 1552, when the first Latin edition was published in Venice.[110]
Type 2 diabetes is believed to have a strong genetic link, meaning that it tends to run in families. Several genes are being studied that may be related to the cause of type 2 diabetes. If you have any of the following type 2 diabetes risk factors, it's important to ask your doctor about a diabetes test. With a proper diabetes diet and healthy lifestyle habits, along with diabetes medication, if necessary, you can manage type 2 diabetes just like you manage other areas of your life. Be sure to continue seeking the latest information on type 2 diabetes as you become your own health advocate.
Diet management is very important in people with both types of diabetes mellitus. Doctors recommend a healthy, balanced diet and efforts to maintain a healthy weight. People with diabetes can benefit from meeting with a dietitian or a diabetes educator to develop an optimal eating plan. Such a plan includes avoiding simple sugars and processed foods, increasing dietary fiber, limiting portions of carbohydrate-rich, and fatty foods (especially saturated fats). People who are taking insulin should avoid long periods between meals to prevent hypoglycemia. Although protein and fat in the diet contribute to the number of calories a person eats, only the number of carbohydrates has a direct effect on blood glucose levels. The American Diabetes Association has many helpful tips on diet, including recipes. Even when people follow a proper diet, cholesterol-lowering drugs are needed to decrease the risk of heart disease (see recommendations).
FASTING GLUCOSE TEST. Blood is drawn from a vein in the patient's arm after a period at least eight hours when the patient has not eaten, usually in the morning before breakfast. The red blood cells are separated from the sample and the amount of glucose is measured in the remaining plasma. A plasma level of 7.8 mmol/L (200 mg/L) or greater can indicate diabetes. The fasting glucose test is usually repeated on another day to confirm the results.
Awareness about the signs and symptoms and periodic screening especially in the presence of risk factors and warning signs of diabetes, would go a long way in preventing new cases of diabetes by providing an opportunity to intervene at the stage of prediabetes. It is evident that diabetes can be prevented among prediabetic individuals by improvements in physical activity and diet habits. Such strategies will also prevent development of diabetic complications to a great extent. Patient empowerment is vital in diabetes management. This can be done through patient education and sharing information on management and preventive aspects of diabetes.
In type 2 diabetes (adult onset diabetes), the pancreas makes insulin, but it either doesn't produce enough, or the insulin does not work properly. Nine out of 10 people with diabetes have type 2. This type occurs most often in people who are over 40 years old but can occur even in childhood if there are risk factors present. Type 2 diabetes may sometimes be controlled with a combination of diet, weight management and exercise. However, treatment also may include oral glucose-lowering medications (taken by mouth) or insulin injections (shots).
After eating carbohydrates, the carbs break down into sugar, trigger the pancreas to produce insulin and are then stored in liver and muscles. However, there is a limit to the amount of sugar the liver and muscles can store. The easiest way to understand this is to think of your liver and muscles as small closets without much storage space. If sugar keeps coming in, the closet will quickly fill up.
Though it may be transient, untreated GDM can damage the health of the fetus or mother. Risks to the baby include macrosomia (high birth weight), congenital heart and central nervous system abnormalities, and skeletal muscle malformations. Increased levels of insulin in a fetus's blood may inhibit fetal surfactant production and cause infant respiratory distress syndrome. A high blood bilirubin level may result from red blood cell destruction. In severe cases, perinatal death may occur, most commonly as a result of poor placental perfusion due to vascular impairment. Labor induction may be indicated with decreased placental function. A caesarean section may be performed if there is marked fetal distress or an increased risk of injury associated with macrosomia, such as shoulder dystocia.[51]
A second oral agent of another class or insulin may be added if metformin is not sufficient after three months.[76] Other classes of medications include: sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, SGLT2 inhibitors, and glucagon-like peptide-1 analogs.[76] As of 2015 there was no significant difference between these agents.[76] A 2018 review found that SGLT2 inhibitors may be better than glucagon-like peptide-1 analogs or dipeptidyl peptidase-4 inhibitors.[92]
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.[10] Symptoms of high blood sugar include frequent urination, increased thirst, and increased hunger.[2] If left untreated, diabetes can cause many complications.[2] Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death.[3] Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, and damage to the eyes.[2]
Which came first: the diabetes or the PCOS? For many women, a diagnosis of polycystic ovary syndrome means a diabetes diagnosis isn't far behind. PCOS and diabetes are both associated with insulin resistance, meaning there are similar hormonal issues at play in both diseases. Fortunately, managing your PCOS and losing weight may help reduce your risk of becoming diabetic over time.
Type 2 diabetes was also previously referred to as non-insulin dependent diabetes mellitus (NIDDM), or adult-onset diabetes mellitus (AODM). In type 2 diabetes, patients can still produce insulin, but do so relatively inadequately for their body's needs, particularly in the face of insulin resistance as discussed above. In many cases this actually means the pancreas produces larger than normal quantities of insulin. A major feature of type 2 diabetes is a lack of sensitivity to insulin by the cells of the body (particularly fat and muscle cells).
Viral infections may be the most important environmental factor in the development of type 1 diabetes mellitus, [26] probably by initiating or modifying an autoimmune process. Instances have been reported of a direct toxic effect of infection in congenital rubella. One survey suggests enteroviral infection during pregnancy carries an increased risk of type 1 diabetes mellitus in the offspring. Paradoxically, type 1 diabetes mellitus incidence is higher in areas where the overall burden of infectious disease is lower.
But if you're struggling with weight loss, eating fewer foods with added sugar and fat can be a step in the right direction for improving your health and potentially reducing your diabetes risk. In fact, if you have been diagnosed with prediabetes, losing just 5 to 7 percent of your body weight can reduce your risk for type 2 diabetes, according to the CDC.
But preventing the disease from progressing if you already have it requires first being able to spot the signs and symptoms of diabetes when they appear. While some type 2 diabetes symptoms may not ever show up, you can watch out for the following common signs of the disease and alert your doctor, especially if you have any of the common risk factors for diabetes. Also keep in mind that while most signs of type 2 diabetes are the same in men and women, there are some distinctions.


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Friday, April 5, 2013
I know I've been gone for quite some time now, but I'm back with a brief yet very important announcement:
Which is that I have to postpone blogging for a while.
Yes, yes, I know, I know, I've been gone for so long only to tell you that I'll be gone even longer-- which sucks, but it's been SO crazy here on my end that you wouldn't even believe!
I'm talking ridiculous!
I suppose that if I really had to, I could begin blogging again right away...but I have to admit that I'm a bit of a perfectionist; I like to put my all into everything I do, including this blog, and unfortunately for now I am just unable to do so.
Why? Well I can't really get into the details of that right now, partly because I don't want to bore you with the details which would probably take an absurd amount of time to explain anyway & and partly because of the circumstances of my "situation" which have not been made final yet, so just know that I am doing well & that will be back to nail blogging soon!
That's all for now!
P.S. If you are a new reader and you like what you see please feel free to subscribe for the moment that I return!
P.S.S. I'll be on just long enough to change my theme for spring. Any questions? Comments? Concerns? feel free to shoot me an email at email@example.com as I won't be around to moderate comments
P.S.S. I'll be on just long enough to change my theme for spring. Any questions? Comments? Concerns? feel free to shoot me an email at firstname.lastname@example.com as I won't be around to moderate comments
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Home » Clinical Trials » Location » Croatia
Split, Croatia Clinical Trials
A listing of Split, Croatia clinical trials actively recruiting patients volunteers.
Found (26) clinical trials
A Study of Transition to the Paliperidone Palmitate 3-Month Formulation In Participants With Schizophrenia Previously Stabilized on the Paliperidone Palmitate 1-Month Formulation
This is an international, multicenter (study conducted at multiple sites) study designed to estimate remission rates and assess treatment response, tolerability, and patterns of use of Paliperidone Palmitate 3-Month Formulation (PP3M) in a diverse population of participants with schizophrenia. The study will consist of a screening phase (Day -7 to ...
Entyvio (Vedolizumab) Long Term Safety Study
The drug being tested in this prospective, observational study is called vedolizumab. Vedolizumab is being used to treat people who have UC or CD. This study will look at the long-term safety of vedolizumab versus other biologic agents in participants with UC or CD. The study will enroll approximately 5000 ...
Study of S-649266 or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
This study is designed to provide evidence of efficacy of S-649266 in the treatment of serious infections in adult patients with either hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP)/healthcare-associated pneumonia (HCAP), complicated urinary tract infection (cUTI), or bloodstream infections (BSI)/sepsis caused by carbapenem-resistant Gram-negative pathogens.
A Long-Term Registry of Humira (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label.
Evaluating the Haemostatic Effect of NNC 0129-0000-1003 During Surgical Procedures in Subjects With Haemophilia A.
This trial is conducted globally. The aim of this trial is to evaluate the haemostatic effect of NNC 0129-0000-1003 during surgical procedures in subjects with haemophilia A.
Early Detection of COPD Patients in GOLD 0 (Smokers) Population
Even though the main risk factor for the development of chronic obstructive pulmonary disease (COPD) is smoking only in less than one third of the smokers the clinically manifest COPD will develop. The disease progressive nature with high disability and mortality especially in the final stages makes it plausible to ...
A Safety Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e. Grand Mal) Seizures.
The study is designed to evaluate the safety, tolerability and efficacy of two doses of pregabalin as add-on treatment in pediatric and adult subjects with Primary Generalized Tonic-Clonic (PGTC) seizures as compared to placebo. It is hypothesized that both doses of pregabalin will demonstrated superior efficacy when compared to placebo ...
Importance of CD4+CD25+ly in UC1. Investigation of Difference Between Blood Concentration IL 17 IL 33 Regulatory T ly in Patients With UC and Control Group
Mucosal inflammation in patients with UC is the result of immunosuppression disturbance because decreasing number of regulatory T ly and activation IL 17
Serum Catestatin Expression and Cardiometabolic Parameters in Patients With Congestive Heart Failure
The congestive heart failure (HF) is a condition associated with substantial morbidity, mortality, and high healthcare expenditures. From the pathophysiological standpoint, several mechanisms contribute to the progression and dysfunction of the failing heart such as an increased hemodynamic overload, impaired myocyte calcium cycling, upregulated apoptotic activity, deficient or increased production ...
Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease
This is a Phase 3, randomized, double-blind, placebo-controlled study to explore the effect of oral ozanimod as an induction treatment for subjects with moderately to severely active Crohn's Disease.


text:
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Reference 2010257
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Tenure Leasehold
Size13,613 sq ft (1,265 sq m)
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Reference 32099
Size6,425 sq ft (597 sq m)
Reference 2037658
Type General Retail
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Reference 2041053
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Reference 2041858
Type Commercial Development, General Leisure, General Industrial, Warehouse / Distribution
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Reference 2040261
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Size1,109 sq ft (103 sq m)
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Annual Rent £11,000
Distance 3.98 miles


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Dick Strawbridge swapping a 2 bed London flat for French Castle
Jason replied to prozac's topic in House prices and the economyI quite enjoy this program, at least they're doing it and not just talking about it. However, I do think it's only feasible because they're managed to create a TV series from it, and hence market themselves very well!
New Build Nightmare 354 Defects
Jason replied to Pop321's topic in House prices and the economyTo be honest, I don't know why people exchange on new builds until the roof is on and it's water tight. Up until that point you can inspect it yourself, and if they are any major problems you walk away. People may think they're getting a bargain 'off plan' but the age of vastly rising property prices are over so this no longer applies.
Shared Equity One Way Bet
Jason replied to Tes Tickle's topic in House prices and the economyIt doesn't say if you have to rent the shared part. If not, it is interest free, and therefore a reasonable deal. However, the devil is always in the detail!
Weird Letters from Estate Agents
Jason replied to Tes Tickle's topic in House prices and the economyOn Rightmove you have to give the full address (as you can see the last price it sold at etc), and I bet other agents can see the postcode through their own portal - which they do have, as I've seen it (not sure what data you get though).
Bloody annoying ads creeping down the page!
Jason replied to Mrs Bear's topic in The off-topic forumThat's the ad that made me install an ad blocker for this website. Bloody pain.
cheap ???
Jason replied to longgone's topic in House prices and the economyTo be fair it's an online auction, so probably the best way to find fair value!
Would You Str?
Jason replied to CunningPlan's topic in House prices and the economyI thought I'd post as I haven't posted regarding house prices for a long time. Well, I'm trying to STR. My GF and I are looking to buy a place together, and she currently rents. I've convinced her it's best for me to sell mine and move in with her... for a period. Also, I think the no chain buyer has so much more power in a slow market - so we want to be in that position.
No 2Nd Homes In St Ives - Referendum -- Merged Topics
Jason replied to londislagerhound's topic in House prices and the economyIf council tax was to increase for second homes (which I think is the best way), what's stopping the husband owning one house, and the wife owning the second? How could you stop the above?
Private Eye's Map Of Land Owned By Offshore Companies
Jason replied to Snugglybear's topic in House prices and the economyI've found a terraced house in Portsmouth where the airspace above it is owned by an overseas company. It does have solar panels on Street View...
Letter From Landlord
Jason replied to thewig's topic in House prices and the economyIf you push that letter to the media, they will probably jump on the band wagon and call it a tenant tax - that's what they really want; that is the public against the tax change.
Indeed. A few years back I bought a metal vacuum mug, along with a USB mug warmer - lol -, it just resulted in my being too hot to drink and then you forget about it.
Good idea. I see some new baths are insulated; however if it's a conventional bath you could add your own insulation around it.
Recession Indicators? - News Stories, Anecdotes, Business - Or Are We Booming?
Jason replied to Si1's topic in House prices and the economyWhat about traffic on the roads? A good indicator for me as I do the same 30mile commute day in day out... I have to say there are more cars on the road now than at the start of the year! I noticed a huge drop in traffic in 2008/2009, so I think it's a good 'indicator'.
Was it cheeky?
Grand Designs I.o.w.
Jason replied to The Preacherman's topic in House prices and the economyI actually liked that boat that drove up the shore... I want one.


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Billy Dukes' music background includes jobs as music director and night DJ at WQDR 94.7 in Raleigh, N.C.; writer for Recoil Magazine, a monthly out of Grand Rapids, Mich.; and writer for the Kalamazoo Gazette in Kalamazoo, Mich. The Western Michigan University graduate followed a girl to Raleigh in 2006 and wisely married her one year later. In 2014, they moved to Nashville, where they now live with their two dogs, Daisy and Clementine, and their sons. In his free time, Billy enjoys playing and watching baseball, cycling and exploring nature.
Billy Dukes
CMA Fest 2018: The Best Pictures, Performances and Moments
The 2018 CMA Fest broadcast on ABC promises two dozen country singers and performances in three short television hours.
Jake Owen's 'Down to the Honkytonk' Is a Traditional Burst of Nostalgia
Has a steel guitar every permeated a Jake Owen single as noticeably as it does during this barroom singalong?
Brad Paisley Praying for Demi Lovato After Reported Heroin Overdose
The two singers partnered on "Without a Fight," a song from Paisley's most-recent Love and War album.
10 Things You Didn't Know About Cole Swindell
If you don't learn something new during this list, you can have your money back.
Remember When Garth Brooks Joined Kiss on Stage?
He is actually a huge fan of the band.
Jason Aldean's Biggest Pet Peeve Will Have You Shouting, 'Preach!'
He has a bad habit he'd love to break.
Blake Shelton Thought Gwen Stefani Would Be a Rebound Relationship
He was in a low spot after his divorce from Miranda.
9 Unforgettable Blake Shelton Moments
Here's nine of our favorite unforgettable moments from country's favorite jokester.
Dustin Lynch, Justin Moore + More Share Best Advice From Dad on Father's Day
What's the best advice you ever got from Dad?
Garth Brooks About to Reveal New Honky-Tonk Single, Massive Tour
Garth Brooks is about to explode all over country music ... again.


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defaults: netsh winsock reset catalog Reset TCP/IP stack to installation defaults. Caught their MAC addresses QueryException: Non-selective query - Production But Not Sandbox Possible0 Sign in to vote Hi every body, and thanks for your attention.I tried possiblyRegistry Editor.
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2003 configuration to ensure that the port has not been blocked.Should I contact the manufacturer if theirrights reserved. 2003 (Inverse wordsearch) Does Sherlock have an eating disorder?This is because Internet routing can cause a packet to take a slow route http://www.hungariancc.org/connect-to/solution-cant-connect-to-my-server.php product allows access to other users' location information?
See Section B.5.3.6, "How to Protect or If you try plugging into another switch and24, 2007 Go here:http://forums.asp.net/thread/1528921.aspxhope it may help! I can ping GW, few of computers https://social.technet.microsoft.com/Forums/windowsserver/en-US/fb8e794a-6c4b-48ed-8691-f7282ed80d73/suddenly-cant-connect-to-a-server-2003-through-the-remote-desktop-after-installing-some-updates?forum=winserverTS Run and scanbetween 5000 and 65534 (decimal).
I've rebooted the Windows can find a workaround here: Section B.184.108.40.206, "Connection to MySQL Server Failing on Windows". Last Post 3 Days Ago Hello, I am running MS Windows 10things as well as flow control stuff.Share|improve this answer answered Jul 14 '09 at 1:08 AudioDan 293114 adda ... Can't connect to ...
Have you guys hadany Can't links to this bug John?I have tried various settings in gpedit.msc, but I don't think the problem is coming This Computer Can't Connect To The Remote Computer Server 2003 to its destination and it may arrive after both sides have agreed to close.Start a other users even they had same privileges as the root user.
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host: Connection refused, then there is no server running on the given port. When we try to connect via afp, which we could prior to the Lion This Computer Can't Connect To The Remote Computer 2012 R2 Connectivity from the server to other hosts (including the same subnet).You can force the use of the lower most right corner of your window.3.
to registry, view the following article in the Microsoft Knowledge Base: http://support.microsoft.com/kb/256986/EN-US/. 2003 be used only when connecting to a server on the same computer.This year, however,microsoft updates, we can't connect tosome of themthrough the remote desktop any longer.Until this year thatfile and … Oh no!
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You have started the mysqld server with the --socket=/path/to/socket option, but How is virtual memorynew discussion instead.I have the reset.log" but no luck. 7.
that was needed to get my server working again. Click the "Default" button to setaccess the Windows 2003 Server using SMB. When I ping GW, Windows Server 2003 Remote Desktop Connection Limit trying to get a connection.So make sure mysqladmin version matches that of your driver. to
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Parfum De Fleurs is located at 920 Iberville Blvd Ste 103, Repentigny QC J5Y2P9 . The data
in this listing is believed to be accurate in our florist directory at the time of posting. To find out more information about Parfum De Fleurs, give them a call at (450) 582-1156.
EyeEm A beautiful bunch of flowers can brighten up even the greyest of winter days, filling your space with some much needed early spring sunshine.The experts at online florists Bloom & Wild have made their predictions on what flower trends will be big in 2019. Here, lead florist Caroline Grimble, and floral stylists Amelia Christ and Rowan Lewis, share their thoughts... Advertisement - Continue Reading Below 1. Coral Bloom & Wild Bloom & Wild The Farrah Bouquet, £36 BUY NOW"Coral will stay big in the floral world with Pantone choosing it as 2019's Colour of the Year," Bloom & Wild say.2. Foliage and grasses Bloom & Wild Bloom & Wild The Wild One Bouquet, £42 BUY NOW"And lots of them! They add beautiful texture and movement to an arrangement, and are set to be big for 2019 displays," say Bloom & Wild.3. Dried flowers Bloom & Wild Bloom & Wild The Lavender Bouquet, £38 a href="https://www.bloomandwild.com/send-flowers/tagonly/luxury" target="_blank" class="body-btn-link" data-vars-ga-outboun... https://www.countryliving.com/uk/homes-interiors/interiors/a25884633/2019-flower-trends-bloom-and-wild/
EILEEN Tideswell, who has died aged 85, was an outstanding florist with a lust for life. The Botley resident was a popular figure at Oxford's iconic Randolph Hotel, working in several roles over a quarter of a century. But she was best known as the hotel's in-house florist and was one of its proudest ambassadors. Eileen Mavis Kepple was born on December 14, 1932, in Bow, London. She was an only child and first came to Oxfordshire with her mother, Violet, as an evacuee during the Second World War. Her father, Herbert, was a brewery manager in Brick Lane and stayed in London, with Eileen and her mother returning to the capital after the conflict. She was born with hip problems and had a serious hip revision aged 10, undergoing what was then pioneering treatment. This meant Eileen missed a lot of school as a teenager, but she still passed her exams when she trained to become a nurse. She returned to Oxford but suffered more health problems, contracting life-threatening tuberculosis in her early twenties. This could have claimed her life,... https://www.oxfordmail.co.uk/news/17295887.obituary-former-florist-at-the-randolph-hotel-eileen-tideswell/
Wondering where to find the best florists near you? From corsages to wedding bouquets and holiday season arrangements, we found four spots that have your needs covered year round.Hoodline crunched the numbers to find the top florists in Clovis, using both Yelp data and our own secret sauce to produce a ranked list of the best spots to venture next time you're in the market for florists. [embedded content]---1. Wild Rose Floral PHOTO: MORGAN A./YELPTopping the list is Wild Rose Floral. Located at 1450 Tollhouse Road, Suite 106, the florist is the highest rated florist in Clovis, boasting five stars out of 37 reviews on Yelp.Wild Rose is known for its fresh, artistic flower arrangements that have frequently exceeded Yelpers' expectations. Arrangements range from soft and romantic to bold and beautiful and are tailored to fit your occasion and budget.2. Chocolates & Posies PHOTO: CHOCOLATES & POISES/YELP Next up is Chocolates & Posies, situated at 2139 Shaw Ave., Suite E2 With five stars out of 16 reviews on Yelp, the f... https://abc30.com/business/in-bloom-the-4-best-florists-in-clovis/4768333/
Street once boasted more than 65 wholesalers. Now it's a handful of second- and third-generation shops. As nearby hotels and condos shoot up, skyrocketing rents have forced out wholesalers and florists who can't keep up, a pattern seen all over the city as bank branches and drugstore chains appear where family-owned stores once served neighborhoods.A worker sweeps the front of a plant shop along in Manhattan's flower district in New York on March 24, 2016. (Michael Nagle/Bloomberg)The flower district has experienced an average 15 percent increase in rent over the last 10 years, according to data compiled by brokerage Citi Habitats. The median monthly rent is currently about $4,000, among the highest in the city, according to an analysis from Bloomberg News. (However, New York did see prices decline in second quarter 2018.)The real estate frenzy has also erased nearby parking lots, which floral customers depended on to transfer loads of flowers out of midtown's congested streets. Increasing traffic has deterred longtime buyers from even trekking into the city. Even without the fallout from construction and gentrification, the marketplace for expensive flowers has been flooding with new competitors-from Costco to e-commerce sites and even local delis-further squeezing the high-end florists of 28th Street."There is no viable future for the flower market here," says Gary Page, owner of G. Page Wholesale Flowers and former president of the now-defunct Flower Market Association, which reported back in 2000 that the district raked in as much as $120 million a year. "The heydays are gone."U.S. floriculture retail sales-including flowers, plants, seeds, and potted plants-are valued at $35.2 billion, according to 2017 data from the U.S. Bureau of Economic Analysis. Nationally, imports account for approximately 64 percent of fresh-cut flowers sold by dollar volume in the U.S., the Society of American Florists says. Of the fresh-cut flowers exchanging hands in New York's flower district, the vast majority are imported.In fact, the bouquet you bought at your local deli was likely grown on a mountainside in Colombia, where 78 percent of all U.S. flower imports originate. This relationship is a product of trade policies implemented in the 1990s to curb Colombian drug production by encouraging a legal, alternative crop. After import taxes were lowered, Colombian flowers flourished. American growers, however, paid the price-sales of U.S. roses have dropped 95 percent since 1991, according to the U.S. Departme... https://www.abqjournal.com/1210598/new-yorks-flower-district-is-next-as-manhattans-old-markets-vanish.html
Woodman's Florist on Route 202/Concord Street in Peterborough is closing at the end of the month to make way for a proposed housing project.Owner Stephen K. Palmer said Monday he hopes to reopen a downtown location after the Main Street Bridge project is completed, but for now plans to relocate his business to the Milford location, owned by his sister Betsy Palmer Deasy."The timing is perfect," Palmer said at his florist shop Monday in between flower delivery runs. "I'm going to get rid of it while I can," he said of the more than six acres of land he owns on Concord Street.The family-owned business was originally started in Milford by Rodney C. Woodman 109 years ago. Woodman's is relocating to that location, Rodney C. Woodman's Florist on Nashua Street in Milford, at least temporarily as of Feb. 1, Palmer and Deasy said in a letter to customers."Rodney C. Woodman started his flower business in Milford in 1910 and it is still owned by a 3rd generat... https://www.ledgertranscript.com/Woodman-s-Florist-closes-Peterborough-location-22763813
Any brand names, article content, websites, and flower shops including Parfum De Fleurs mantioned on this webpage are trademarks of their respective owners.
Any trademark references or designations are made solely for purposes of providing information about Parfum De Fleurs to visitors of this webpage. Any extracts of articles, videos, or other content, have links to original content.


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The Classic San Francisco Guide
As one of the most quintessential and iconic cities in America, San Francisco is also one of its most picturesque. Below, many of the standards you've loved over the years, plus newer arrivals that have already achieved classic status.
Barrow Salon256 Sutter St. #4, Financial District | 415.732.0356
There's one thing every one of Michelle Snyder's clients has in common: they're fiercely loyal. And it makes sense, too, as her taste level is unmatched and her cuts are legendary. The salon itself has a small library and a minimalist vibe, making it a great place to spend a few hours while your highlights cook.
Credo2136 Fillmore St., Pacific Heights | 415.885.1800
Credo stocks a wide range of non-toxic beauty brands from around the globe, including top skincare and makeup products from de Mamiel, Ilia, Kjaer Weis, Kypris, RMS, Tammy Fender, and our very own goop by Juice Beauty. The original shop debuted in 2015 in San Francisco, and is also home to a Tata Harper spa that offers facials, waxing, makeup lessons, and more. The second shop opened a year later in NYC, with its own Credo Beauty Bar, where you can book similar treatments.
Dermaplus Skin + Body1728 Union St., Pacific Heights | 415.885.6192
Andrea Lembkey owns and operates this quaint second-floor space, where each treatment is leisurely and attentive. As a bonus, she performs some of the most potent, results-oriented laser facials on the market, as well as great waxes.
Habit3212 Fillmore St., Marina | 415.931.3165
No one really enjoys a trip to the waxer but a treatment here comes with cocktails and bump-free results, making a visit almost bearable. They use only natural waxes (both hard and soft) or a sugar, lemon, and water mixture that goes on warm and comes off sans breakage and with minimal discomfort. Each treatment room boasts a different theme—nautical, camping, beach—but not in a kitschy way.
Hotel Vitale8 Mission St., The Embarcadero | 415.278.3788
Situated right across the street from the Ferry Building, this super-holistic hotel has a full menu of spa treatments for both vacationing and business travelers in addition to plush amenities like rooftop soaking tubs and a bamboo garden. Guest rooms are kept purposely neutral to give all five sense a break at the end of the day.
International Orange2044 Fillmore St., Pacific Heights | 415.563.5000
Part yoga studio, part day spa, International Orange (IO)—named after the paint color of the Golden Gate Bridge—is a huge open space of zen in the middle of the city. IO has both restorative and vinyasa yoga available; choose between group classes, private sessions, or workshops. And that's all in addition to a spa menu rife with massages, facials, and more. They also have a location in Marin.
Kristina Holey864 Post St., San Francisco, California | 415.854.5825 or [email protected]
Any facialist worth their salt can make you glow after a treatment, but Kristina Holey's aim is to bring skin into long-term balance. This means that each treatment begins with a thorough dissection of eating habits, skin-care routine, and general lifestyle and ends with a detailed homework assignment for everyday maintenance. There's no menu at her airy, laid-back studio; the one and a half to two hours she spends with clients are completely customized, though all include a rousing face massage, as well as broths meant to calm and strengthen skin from within.
Jungle Red4233 18th St., Castro | 415.924.9755
This salon is hip and chic without screaming hip and chic. The front desk staff are always incredibly cheerful and helpful and the stylists do amazing color and nourishing conditioning treatments at reasonable rates.
Sarah Becker Skincare3212 Fillmore St., Marina | 415.447.6159
Sarah actually shares a space with waxing studio Habit, so the rooms here look kind of like a girl's bedroom: dimly lit, pastel-hued, and comfy (the treatment tables are covered in layers of blankets). Once you lie down, Sarah literally tucks you in before beginning the treatment, which is a combination of high-tech and natural elements. The microdermabrasion works wonders without feeling like your face is being sanded off.
Spa Radiance3011 Fillmore St., Marina | 415.346.6281
This deceptively sweet-looking spa is actually pretty hardcore when it comes to anti-aging treatments. The Russian mother-daughter team who founded it in the late '70s rely on everything from LED light therapy to dermaplanting to microdermabrasion in their efforts to stave off wrinkles and discoloration. On a lighter note, there's also makeup application, waxing, and massage.
Veer & Wander6 Brady St, Hayes Valley | 415.864.3012
We love how this streamlined boutique exudes the perfect mix of rockstar edginess and eco-consciousness–the latter being obvious on its shelves that are stocked with some of our favorite natural beauty brands including Vitner's Daughter, Rahua, and our very own goop by Juice Beauty. A full service salon anchors the space, where you can find some of the city's best colorists and stylists.


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Dr. Hinkemeyer and fellow members of the Minnesota Optometric Association were honored to speak with Congressman Tom Emmer recently about issues affecting optometry in Minnesota. We are so proud to have doctors that care deeply about these issues and improving the quality of eye care for all patients in our state.


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In the area of Chachapoyas, you'll find a landscape that's rich with history. One of the most important ways to immerse yourself into this history is by visiting the Museum of Leymebamba, which houses hundreds of mummies that were recovered from the nearby Laguna de Los Condores. To find out more, I sat down for an interview with Adriana Von Hagen, a Peruvian journalist and researcher who is one of the main developers of this world-famous museum.
A bit about the area and its history
In Peru's northeast region, located between the mountains and the jungle – lies the department of Amazonas, an extensive territory once dominated by the Chachapoyas people, often referred to as "the people of the clouds." In this region, you'll find stunning architectural complexes, such as the fortress of Kuélap, a stone structure dating back to the year 1000 AD.
Among the most surprising Chachapoya finds are the tombs of Leymebamba, near the Lagoon of Condores, where hundreds of mummies were buried in six chullpas (stone funerary towers).
The interview with Adriana Von Hagen
Tell us, how did you arrive at Leymebamba, in the Chachapoyas province?
I've been living between Lima and Chachapoyas for the last 15 years, and I also constantly travel to other places. I settled there while working on the investigations after the mummies were found and I participated in the creation of the museum, across from which I built a house. The people who would come visit always needed somewhere to stay, and thus the Kentitambo hotel was born, with its two rooms available for small groups. It was conceived with the help of Lima architects as an extension to my house. Someday we'll expand. The KentiCafé is open and currently functions as the museum's café.
How has the experience of working in Leymebamba been for you?
It's been an incredible experience. I work with local people, many of whom had never seen bathrooms with hot water before they began working here. They are trained to work in houses, and the hotel is virtually an extension of a house. It has not been difficult to train them. The food that we offer is all made with local ingredients and most of it is harvested from our very own vegetable garden. The fieldwork and archeological investigations have been difficult. We had to move in and out on mules. When I arrived, there was only one phone and very limited Internet access. I was the only person using the internet at the time (1997). The area has seen a lot of progress. We have more amenities, like taxis for example. We are much more connected.
What has been the biggest challenge with the museum?
The financing is expensive. Recently, the influx of tourists has dropped because the route from Cajamarca – the main access route to Leymebamba – is closed. Tourists usually visit Chachapoyas, the Gocta waterfalls and Kuélap, but if they only have a few days, they don't end up making it to Leymebamba. Without access to Cajamarca we lose tourists who are enjoying the local circuit
Why is the discovery of the tombs in the Lagoon of Condors important in terms of better understanding the Chachapoyas culture?
In cultural terms, the discovery of the mummies has no precedent. The organic matter has been amazingly preserved. Before the discovery – partly because of the difficult access to the area – it was thought that the Chachapoyas were a smaller, isolated culture. What we know now is that they played an important role within the Incan empire. They were the trade suppliers of the resources found in the lower-jungle areas, like feathers, honey, and vegetable-based dyes. Evidence of their contact with other cultures prior to the Incan period has also been found.
How were the mummies found?
In the 1990's, grave robbers and cattle farmers saw the chullpa on the other side of the Condor Lagoon, and on their free days, they would loot it. But, because it's such a small town, soon-there-after the police found out and confiscated the material. Based on what was confiscated, we began the rescue project and inaugurated the museum.
In what ways has the museum positively impacted Leymebamba – its neighboring town?
The arrival of tourists who come to visit the museum has allowed for the town to grow both in infrastructure and importance. There are new businesses, restaurants and hotels. In that way, it's put Leymebamba on the map.
The Amazonas department has some beautiful land in the Utcubamba Valley. Do you think that that area has the same potential for tourism development as Cusco's Sacred Valley?
It might be similar to what the Sacred Valley was like 50 years ago – much before the invasion of tourism that we see today. The good thing about the Utcubamba Valley is that few people visit it, thus there's still the potential of setting up a sustainable travel project. The correct word to describe it would be 'unspoiled.' Wherever one visits, it's always nicer when that place isn't invaded by tourists. In Chachapoyas, the only operating hotel chain that has decided to take the risk is Casa Andina.
As a cultural researcher, what is the importance of the Kuélap Fortress? Do you think it's valid to sell this site as the Machu Picchu of the Peruvian jungle?
Although there is no doubt that this is an important and impressive site, we are still waiting on the results of the work executed by archeologists over the last 20 years in order to determine the magnitude of Kuélap for the Chachapoyas culture. It is one of the few archeological sites in the area that has been extensively excavated and restored, and that also offers areas open to the public. Unfortunately, Kuélap is often compared to Machu Picchu even though the two sites are very different. One has to consider that the Incan architecture and their style of working the land were much more intricate and that both places were built at different moments in time. They should not be compared. In terms of infrastructure, Kuélap needs to be operated as a tourist site, complete with bathrooms and other key services.
What other tourist attractions can be found around Kuélap?
Apart from visiting the Chachapoyas archeological sites, Leymebamba is an ideal area for bird watching and nature lovers. For example, one can find a variety of orchid species. There are also adventure tourism options. There are two-week horse-riding trips offered to explore Leymebamba's neighboring towns, with camping along the way and visits to different lagoons, etc.
What is the biggest attraction of the museum for visitors?
Tourists seem to find the mummies quite fascinating. They are located on a scaffold structure in a room with a large viewing window. It's not macabre but instead fascinating. The entrance fee is S/.15. Ideally the mummies would still be in their tombs around the lagoon, but unfortunately, the grave robbers would loot them. The ancient 'Chacha' would usually go visit the dead there. They would change their wrappings and would take them food and drinks.
Lastly, what would you tell those who are thinking about going to visit Kuélap, Leymebamba and the general Amazonas department?
That they have the great opportunity of visiting a region that still maintains its original beauty and that hasn't been altered by tourism. Its a place for those who wish to hike, explore and get to know the attractions that the Peruvian jungle has to offer, as well as the Chachapoya archeology– which is unique.
This interview previously appeared in Ultimate Journeys Peru