text:
Everolimus With or Without Bevacizumab in Treating Patients With Advanced Kidney Cancer That Progressed After First-Line Therapy
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01198158
Recruitment Status : Terminated
First Posted : September 9, 2010
Last Update Posted : September 27, 2018
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|Condition or disease
|Clear Cell Renal Cell Carcinoma Recurrent Renal Cell Carcinoma Stage III Renal Cell Cancer AJCC v7 Stage IV Renal Cell Cancer AJCC v7
|Biological: Bevacizumab Drug: Everolimus Other: Laboratory Biomarker Analysis Other: Pharmacological Study
|Phase 3
l. To compare the overall survival of patients receiving bevacizumab plus everolimus and everolimus alone among patients with advanced renal cell carcinoma progressing after first line vascular epidermal growth factor receptor (VEGFR)-tyrosine kinase inhibitor (TKI) treatment.
I. To compare the progression-free survival and proportion who experience an objective response (defined as complete clinical response [cCR] + partial response [PR]) in patients with advanced renal cell carcinoma receiving bevacizumab plus everolimus and everolimus alone.
II. To compare grade 3 or higher toxicity in patients receiving each treatment regimen.
OUTLINE: Patients are randomized to 1 of 2 treatment arms.
ARM I: Patients receive everolimus orally (PO) once daily (QD) on days 1-28.
ARM II: Patients receive everolimus PO QD on days 1-28 and bevacizumab intravenously (IV) over 30-90 minutes on days 1 and 15.
In both arms, courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed up every 8 weeks until disease progression and then every 6 months for up to 5.5 years.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|78 participants
|Intervention Model:
|Parallel Assignment
|Double (Participant, Investigator)
|Primary Purpose:
|Official Title:
|Randomized Phase III Trial Comparing Everolimus Versus Everolimus Plus Bevacizumab for Advanced Renal Cell Carcinoma Progressing After Treatment With Tyrosine Kinase Inhibitors
|Actual Study Start Date :
|September 15, 2010
|Actual Primary Completion Date :
|December 15, 2017
|Actual Study Completion Date :
|December 16, 2017
Active Comparator: Arm I (everolimus)
Patients receive everolimus PO QD on days 1-28.
Drug: Everolimus
Given PO
Other Names:
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Pharmacological Study
Correlative studies
Experimental: Arm II (everolimus with bevacizumab)
Patients receive everolimus PO QD on days 1-28 and bevacizumab IV over 30-90 minutes on days 1 and 15.
Biological: Bevacizumab
Given IV
Other Names:
Drug: Everolimus
Given PO
Other Names:
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Pharmacological Study
Correlative studies
- Overall survival (OS) [ Time Frame: The time from date of randomization to date of death due to any cause, assessed up to 5.5 years ]The stratified log-rank statistic will be the primary analysis to compare the two treatment arms on OS adjusting on the stratification factors (number of negative prognostic factors (0, 1, 2-3) and prior VEGFR-TKI therapy (< 12 weeks, >= 12 weeks). The Kaplan-Meier product-limit estimator will be used to estimate the OS distribution. In addition, the proportional hazards model will be used to assess the importance of the treatment arm adjusting on patient characteristics, stratification variables and other important covariates in predicting OS.
- Progression-free survival (PFS) [ Time Frame: The time from randomization to disease progression or death from any cause, assessed up to 5.5 years ]The stratified log-rank statistic will be the primary analysis to compare the two treatment arms on PFS adjusting on the stratification factors (number of negative prognostic factors (0, 1, 2-3) and prior VEGFR-TKI therapy (< 12 weeks, >= 12 weeks). The Kaplan-Meier product-limit estimator will be used to estimate the PFS distribution. In addition, the proportional hazards model will be used to assess the importance of the treatment arm adjusting on patient characteristics, stratification variables and other important covariates in predicting PFS.
- Objective response rate (defined as confirmed complete response plus partial response) [ Time Frame: Up to 5.5 years ]Furthermore, the Cochran-Mantel-Haenszel test will be used to compare the two arms on the proportion of patients who experience an objective response (defined as either a confirmed CR or a PR) adjusting on the stratification factors (number of negative prognostic features and prior VEGFR-TKI therapy.
- Toxicities, graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0 [ Time Frame: Up to 30 days after completion of study treatment ]The Fisher exact test will be used to compare the two treatment arms on the proportion of patients with unacceptable treatment related grade 3 or higher toxicity.
- Cutpoints for change in biomarker levels [ Time Frame: Baseline to 8 weeks ]Statistical methods based on exact asymptotic distributions will be used to find a cutpoint (other than the median) for change in each biomarker at 8 weeks from baseline.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Renal cell carcinoma with some component of clear cell histology
- Metastatic or unresectable disease
- Must have been treated with at least 1 prior VEGFR tyrosine kinase inhibitor treatment and have progressed or have been intolerant to treatment
- No prior systemic therapy with a vascular endothelial growth factor (VEGF) binding agent (e.g., bevacizumab)
- No prior systemic therapy with any mechanistic target of rapamycin (mTOR) inhibitor (e.g., sirolimus, temsirolimus, everolimus)
- Prior cytokine therapy is allowed
- Any systemic therapy must be completed at least 4 weeks prior to registration
- >= 2 weeks since any prior radiation (including palliative)
Patients must not have had a major surgical procedure, open biopsy, or significant traumatic injury within 4 weeks prior to study registration, and must have fully recovered from any such procedure
- The following are not considered to be major procedures: thoracentesis, paracentesis, port placement, laparoscopy, thoracoscopy, bronchoscopy, endoscopic ultrasonographic procedures, mediastinoscopy, skin biopsies, incisional biopsies and routine dental procedures
- Patients must have measurable disease by RECIST criteria; lesions that can be accurately measured in at least one dimension (longest diameter to be recorded) as >= 2 cm with conventional techniques or as >= 1 cm with spiral computed tomography (CT) scan
No active brain metastases: patients with treated, stable brain metastases for at least three months are eligible as long as they meet the following criteria:
- Treated brain metastases are defined as having no ongoing requirement for steroids and no evidence of progression or hemorrhage after treatment for at least 3 months, as ascertained by clinical examination and brain imaging (magnetic resonance imaging [MRI] or CT) (stable dose of anticonvulsants are allowed); treatment for brain metastases may include whole brain radiotherapy (WBRT), radiosurgery (RS; Gamma Knife, linear accelerator [LINAC], or equivalent) or a combination as deemed appropriate by the treating physician; patients with central nervous system (CNS) metastases treated by neurosurgical resection or brain biopsy performed within 3 months prior to day 1 are not eligible
- Baseline brain imaging (MRI/CT) is required
- No serious non-healing wound, ulcer, or bone fracture
No arterial thrombotic events within 6 months of registration:
- Including transient ischemic attack (TIA), cerebrovascular accident (CVA), peripheral arterial thrombus, unstable angina or angina requiring surgical or medical intervention in the past 6 months, or myocardial infarction (MI); patients with clinically significant peripheral artery disease (i.e., claudication on less than one block), significant vascular disease (i.e., aortic aneurysm, history of aortic dissection), or any other arterial thrombotic event are ineligible
- Patients who have experienced a deep venous thrombosis or pulmonary embolus within the past 6 months must be on stable therapeutic anticoagulation to be enrolled to this study
- Patients receiving anti-platelet agents and prophylactic anticoagulation are eligible
- No inadequately controlled hypertension: (defined as a blood pressure of >= 160 mmHg systolic and/or >= 90 mmHg diastolic on medication), or any prior history of hypertensive crisis or hypertensive encephalopathy
No known severe impairment of lung function, defined as >= grade 2 dyspnea or cough, or either:
- Requirement of supplemental oxygen, or
- In cases where pulmonary function or pulse oximetry tests have been obtained, forced expiratory volume of the lung in one second (FEV1) or forced vital capacity (FVC) are < 50% of predicted, or single breath diffusing capacity of the lung for carbon monoxide (DLCO) is < 35% of predicted or resting room oxygen saturation is less than 90%
- No active or severe liver disease (e.g. acute or chronic hepatitis, cirrhosis)
- No positive serology for anti-hemoglobin C (HBC) or anti-hepatitis C virus (HCV) antibodies; hepatitis B virus (HBV) seropositive patients (hepatitis B surface antigen [HBsAg] positive) are eligible if they are closely monitored for evidence of active HBV infection by HBV deoxryribonucleic acid (DNA) testing and agree to receive suppressive therapy with lamivudine or other HBV-suppressive therapy until at least 4 weeks after the last dose of everolimus
- No New York Heart Association (NYHA) class >= 2 congestive heart failure
- No active bleeding or chronic hemorrhagic diathesis or increased risk for bleeding: Including but not limited to history of major bleeding within 6 months (e.g. gastrointestinal, lung, CNS sites; or required transfusion support)
- No history of abdominal fistula, gastrointestinal perforation or intra-abdominal abscess within 6 months prior to the initiation of treatment
- No ongoing immunosuppressive therapy: including chronic systemic treatment with corticosteroids (>= 10 mg/day prednisone equivalent)
- Archival tissue must be available for submission: though it is optional patients to choose to participate in the correlative substudies or not
Patients who are pregnant or nursing are not eligible
- Women of child bearing potential must have a negative serum or urine pregnancy test within 16 days prior to registration
Women of child-bearing potential include:
- Any female who has experienced menarche and who has not undergone surgical sterilization (hysterectomy, bilateral tubal ligation or bilateral oophorectomy) or is not postmenopausal (defined as amenorrhea >= 12 consecutive months)
- Women on hormone replacement therapy (HRT) with documented serum follicle stimulating hormone (FSH) level > 35m IU/mL
- Women who are using oral, implanted or injectable contraceptive hormones or mechanical products such as an intrauterine device or barrier methods (diaphragm, condoms, spermicides) to prevent pregnancy or practicing abstinence or where partner is sterile (e.g., vasectomy)
- Performance status Eastern Cooperative Oncology Group (ECOG) 0-2 or Karnofsky score >= 60%
- Granulocytes >= 1,500/μL
- Platelet count >= 100,000/μL
- Calculated creatinine clearance >= 30 mL/minute (modified Cockroft and Gault formula)
- Bilirubin =< 1.5 x upper limits of normal
- Aspartate aminotransferase (AST) =< 2.5 x upper limits of normal (ULN)
- Fasting serum triglycerides =< 200 mg/dL
- Serum cholesterol =< 300 mg/dL
- Fasting serum glucose =< 1.5 x ULN
- Urine protein to creatinine ratio < 1.0 or urine protein =< 1+
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01198158
Hide Study Locations
|United States, Arizona
|Mayo Clinic in Arizona
|Scottsdale, Arizona, United States, 85259
|United States, Arkansas
|Fowler Family Center for Cancer Care
|Jonesboro, Arkansas, United States, 72401
|University of Arkansas for Medical Sciences
|Little Rock, Arkansas, United States, 72205
|United States, California
|Kaiser Permanente-Anaheim
|Anaheim, California, United States, 92806
|Kaiser Permanente-Deer Valley Medical Center
|Antioch, California, United States, 94531
|PCR Oncology
|Arroyo Grande, California, United States, 93420
|Kaiser Permanente-Baldwin Park
|Baldwin Park, California, United States, 91706
|Kaiser Permanente-Bellflower
|Bellflower, California, United States, 90706
|Alta Bates Summit Medical Center-Herrick Campus
|Berkeley, California, United States, 94704
|Mills-Peninsula Medical Center
|Burlingame, California, United States, 94010
|East Bay Radiation Oncology Center
|Castro Valley, California, United States, 94546
|Valley Medical Oncology Consultants-Castro Valley
|Castro Valley, California, United States, 94546
|Bay Area Breast Surgeons Inc
|Emeryville, California, United States, 94608
|Epic Care Partners in Cancer Care
|Emeryville, California, United States, 94608
|Kaiser Permanente-Fontana
|Fontana, California, United States, 92335
|Kaiser Permanente-Fremont
|Fremont, California, United States, 94538
|Valley Medical Oncology Consultants-Fremont
|Fremont, California, United States, 94538
|Kaiser Permanente-Fresno
|Fresno, California, United States, 93720
|Kaiser Permanente - Harbor City
|Harbor City, California, United States, 90710
|Kaiser Permanente-Irvine
|Irvine, California, United States, 92618
|UC San Diego Moores Cancer Center
|La Jolla, California, United States, 92093
|Kaiser Permanente Los Angeles Medical Center
|Los Angeles, California, United States, 90027
|Kaiser Permanente-Cadillac
|Los Angeles, California, United States, 90034
|Contra Costa Regional Medical Center
|Martinez, California, United States, 94553-3156
|Memorial Medical Center
|Modesto, California, United States, 95355
|El Camino Hospital
|Mountain View, California, United States, 94040
|Sutter Cancer Research Consortium
|Novato, California, United States, 94945
|Highland General Hospital
|Oakland, California, United States, 94602
|Alta Bates Summit Medical Center - Summit Campus
|Oakland, California, United States, 94609
|Bay Area Tumor Institute
|Oakland, California, United States, 94609
|Hematology and Oncology Associates-Oakland
|Oakland, California, United States, 94609
|Tom K Lee Inc
|Oakland, California, United States, 94609
|Kaiser Permanente Oakland-Broadway
|Oakland, California, United States, 94611
|Kaiser Permanente-Oakland
|Oakland, California, United States, 94611
|Kaiser Permanente - Panorama City
|Panorama City, California, United States, 91402
|Kaiser Permanente-Rancho Cordova Cancer Center
|Rancho Cordova, California, United States, 95670
|Kaiser Permanente-Redwood City
|Redwood City, California, United States, 94063
|Kaiser Permanente-Richmond
|Richmond, California, United States, 94801
|Kaiser Permanente-Riverside
|Riverside, California, United States, 92505
|Rohnert Park Cancer Center
|Rohnert Park, California, United States, 94928
|Kaiser Permanente-Roseville
|Roseville, California, United States, 95661
|The Permanente Medical Group-Roseville Radiation Oncology
|Roseville, California, United States, 95678
|Kaiser Permanente-South Sacramento
|Sacramento, California, United States, 95823
|South Sacramento Cancer Center
|Sacramento, California, United States, 95823
|Kaiser Permanente - Sacramento
|Sacramento, California, United States, 95825
|Kaiser Permanente-San Diego Mission
|San Diego, California, United States, 92108
|Kaiser Permanente-San Diego Zion
|San Diego, California, United States, 92120
|Zuckerberg San Francisco General Hospital
|San Francisco, California, United States, 94110
|California Pacific Medical Center-Pacific Campus
|San Francisco, California, United States, 94115
|Kaiser Permanente-San Francisco
|San Francisco, California, United States, 94115
|UCSF Medical Center-Mount Zion
|San Francisco, California, United States, 94115
|Kaiser Permanente-Santa Teresa-San Jose
|San Jose, California, United States, 95119
|Kaiser Permanente San Leandro
|San Leandro, California, United States, 94577
|Kaiser Permanente-San Marcos
|San Marcos, California, United States, 92078
|Doctors Medical Center- JC Robinson Regional Cancer Center
|San Pablo, California, United States, 94806
|Kaiser Permanente-San Rafael
|San Rafael, California, United States, 94903
|Kaiser Permanente Medical Center - Santa Clara
|Santa Clara, California, United States, 95051
|Kaiser Permanente-Santa Rosa
|Santa Rosa, California, United States, 95403
|Sutter Pacific Medical Foundation
|Santa Rosa, California, United States, 95403
|Kaiser Permanente Cancer Treatment Center
|South San Francisco, California, United States, 94080
|Kaiser Permanente-South San Francisco
|South San Francisco, California, United States, 94080
|Kaiser Permanente-Stockton
|Stockton, California, United States, 95210
|Kaiser Permanente Medical Center-Vacaville
|Vacaville, California, United States, 95688
|Kaiser Permanente-Vallejo
|Vallejo, California, United States, 94589
|Sutter Solano Medical Center/Cancer Center
|Vallejo, California, United States, 94589
|Kaiser Permanente-Walnut Creek
|Walnut Creek, California, United States, 94596
|Kaiser Permanente-Woodland Hills
|Woodland Hills, California, United States, 91367
|United States, Colorado
|The Medical Center of Aurora
|Aurora, Colorado, United States, 80012
|Boulder Community Hospital
|Boulder, Colorado, United States, 80301
|Penrose-Saint Francis Healthcare
|Colorado Springs, Colorado, United States, 80907
|Kaiser Permanente-Franklin
|Denver, Colorado, United States, 80205
|Porter Adventist Hospital
|Denver, Colorado, United States, 80210
|Presbyterian - Saint Lukes Medical Center - Health One
|Denver, Colorado, United States, 80218
|SCL Health Saint Joseph Hospital
|Denver, Colorado, United States, 80218
|Rose Medical Center
|Denver, Colorado, United States, 80220
|Colorado Cancer Research Program NCORP
|Denver, Colorado, United States, 80222
|Swedish Medical Center
|Englewood, Colorado, United States, 80113
|Poudre Valley Hospital
|Fort Collins, Colorado, United States, 80524
|Saint Mary's Hospital and Regional Medical Center
|Grand Junction, Colorado, United States, 81501
|North Colorado Medical Center
|Greeley, Colorado, United States, 80631
|Kaiser Permanente-Rock Creek
|Lafayette, Colorado, United States, 80026
|Saint Anthony Hospital
|Lakewood, Colorado, United States, 80228
|Littleton Adventist Hospital
|Littleton, Colorado, United States, 80122
|Sky Ridge Medical Center
|Lone Tree, Colorado, United States, 80124
|Longmont United Hospital
|Longmont, Colorado, United States, 80501
|McKee Medical Center
|Loveland, Colorado, United States, 80539
|Parker Adventist Hospital
|Parker, Colorado, United States, 80138
|Saint Mary Corwin Medical Center
|Pueblo, Colorado, United States, 81004
|North Suburban Medical Center
|Thornton, Colorado, United States, 80229
|SCL Health Lutheran Medical Center
|Wheat Ridge, Colorado, United States, 80033
|United States, Connecticut
|Hartford Hospital
|Hartford, Connecticut, United States, 06102
|The Hospital of Central Connecticut
|New Britain, Connecticut, United States, 06050
|Eastern Connecticut Hematology and Oncology Associates
|Norwich, Connecticut, United States, 06360
|Stamford Hospital/Bennett Cancer Center
|Stamford, Connecticut, United States, 06904
|United States, Delaware
|Beebe Medical Center
|Lewes, Delaware, United States, 19958
|Christiana Care Health System-Christiana Hospital
|Newark, Delaware, United States, 19718
|United States, District of Columbia
|MedStar Georgetown University Hospital
|Washington, District of Columbia, United States, 20007
|MedStar Washington Hospital Center
|Washington, District of Columbia, United States, 20010
|Sibley Memorial Hospital
|Washington, District of Columbia, United States, 20016
|United States, Florida
|Holy Cross Hospital
|Fort Lauderdale, Florida, United States, 33308
|Jupiter Medical Center
|Jupiter, Florida, United States, 33458
|Mount Sinai Medical Center
|Miami Beach, Florida, United States, 33140
|21st Century Oncology-Orange Park
|Orange Park, Florida, United States, 32073
|Florida Hospital Orlando
|Orlando, Florida, United States, 32803
|UF Cancer Center at Orlando Health
|Orlando, Florida, United States, 32806
|Sacred Heart Hospital
|Pensacola, Florida, United States, 32504
|Cleveland Clinic-Weston
|Weston, Florida, United States, 33331
|United States, Georgia
|Phoebe Putney Memorial Hospital
|Albany, Georgia, United States, 31701
|Medical Center of Central Georgia
|Macon, Georgia, United States, 31201
|Memorial Health University Medical Center
|Savannah, Georgia, United States, 31404
|United States, Hawaii
|Pali Momi Medical Center
|'Aiea, Hawaii, United States, 96701
|Hawaii Cancer Care Inc-POB II
|Honolulu, Hawaii, United States, 96813
|Queen's Medical Center
|Honolulu, Hawaii, United States, 96813
|Straub Clinic and Hospital
|Honolulu, Hawaii, United States, 96813
|University of Hawaii Cancer Center
|Honolulu, Hawaii, United States, 96813
|Hawaii Oncology Inc-Kuakini
|Honolulu, Hawaii, United States, 96817
|The Cancer Center of Hawaii-Liliha
|Honolulu, Hawaii, United States, 96817
|Kaiser Permanente Moanalua Medical Center
|Honolulu, Hawaii, United States, 96819
|Kapiolani Medical Center for Women and Children
|Honolulu, Hawaii, United States, 96826
|Castle Medical Center
|Kailua, Hawaii, United States, 96734
|Wilcox Memorial Hospital and Kauai Medical Clinic
|Lihue, Hawaii, United States, 96766
|Maui Memorial Medical Center
|Wailuku, Hawaii, United States, 96793
|Pacific Cancer Institute of Maui
|Wailuku, Hawaii, United States, 96793
|United States, Idaho
|Saint Luke's Mountain States Tumor Institute
|Boise, Idaho, United States, 83712
|Saint Luke's Mountain States Tumor Institute - Fruitland
|Fruitland, Idaho, United States, 83619
|Saint Luke's Mountain States Tumor Institute - Meridian
|Meridian, Idaho, United States, 83642
|Saint Luke's Mountain States Tumor Institute - Nampa
|Nampa, Idaho, United States, 83686
|Saint Luke's Mountain States Tumor Institute-Twin Falls
|Twin Falls, Idaho, United States, 83301
|United States, Illinois
|Saint Joseph Medical Center
|Bloomington, Illinois, United States, 61701
|Illinois CancerCare-Bloomington
|Bloomington, Illinois, United States, 61704
|Graham Hospital Association
|Canton, Illinois, United States, 61520
|Illinois CancerCare-Canton
|Canton, Illinois, United States, 61520
|Illinois CancerCare-Carthage
|Carthage, Illinois, United States, 62321
|Memorial Hospital
|Carthage, Illinois, United States, 62321
|Jesse Brown Veterans Affairs Medical Center
|Chicago, Illinois, United States, 60612
|John H Stroger Jr Hospital of Cook County
|Chicago, Illinois, United States, 60612
|University of Illinois
|Chicago, Illinois, United States, 60612
|Presence Resurrection Medical Center
|Chicago, Illinois, United States, 60631
|University of Chicago Comprehensive Cancer Center
|Chicago, Illinois, United States, 60637
|Weiss Memorial Hospital
|Chicago, Illinois, United States, 60640
|Decatur Memorial Hospital
|Decatur, Illinois, United States, 62526
|Heartland Cancer Research NCORP
|Decatur, Illinois, United States, 62526
|Eureka Hospital
|Eureka, Illinois, United States, 61530
|Illinois CancerCare-Eureka
|Eureka, Illinois, United States, 61530
|Illinois CancerCare-Galesburg
|Galesburg, Illinois, United States, 61401
|Illinois CancerCare-Havana
|Havana, Illinois, United States, 62644
|Mason District Hospital
|Havana, Illinois, United States, 62644
|Presence Saint Mary's Hospital
|Kankakee, Illinois, United States, 60901
|Illinois CancerCare-Kewanee Clinic
|Kewanee, Illinois, United States, 61443
|AMITA Health Adventist Medical Center
|La Grange, Illinois, United States, 60525
|Illinois CancerCare-Macomb
|Macomb, Illinois, United States, 61455
|Mcdonough District Hospital
|Macomb, Illinois, United States, 61455
|Loyola University Medical Center
|Maywood, Illinois, United States, 60153
|Holy Family Medical Center
|Monmouth, Illinois, United States, 61462
|Illinois CancerCare-Monmouth
|Monmouth, Illinois, United States, 61462
|Good Samaritan Regional Health Center
|Mount Vernon, Illinois, United States, 62864
|Bromenn Regional Medical Center
|Normal, Illinois, United States, 61761
|Community Cancer Center Foundation
|Normal, Illinois, United States, 61761
|Illinois CancerCare-Community Cancer Center
|Normal, Illinois, United States, 61761
|Advocate Christ Medical Center
|Oak Lawn, Illinois, United States, 60453-2699
|Illinois CancerCare-Ottawa Clinic
|Ottawa, Illinois, United States, 61350
|Ottawa Regional Hospital and Healthcare Center
|Ottawa, Illinois, United States, 61350
|Illinois CancerCare-Pekin
|Pekin, Illinois, United States, 61554
|OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
|Pekin, Illinois, United States, 61554
|Proctor Hospital
|Peoria, Illinois, United States, 61614
|Illinois CancerCare-Peoria
|Peoria, Illinois, United States, 61615
|Methodist Medical Center of Illinois
|Peoria, Illinois, United States, 61636
|OSF Saint Francis Medical Center
|Peoria, Illinois, United States, 61637
|Illinois CancerCare-Peru
|Peru, Illinois, United States, 61354
|Illinois Valley Hospital
|Peru, Illinois, United States, 61354
|Illinois CancerCare-Princeton
|Princeton, Illinois, United States, 61356
|Perry Memorial Hospital
|Princeton, Illinois, United States, 61356
|West Suburban Medical Center
|River Forest, Illinois, United States, 60305
|Swedish American Hospital
|Rockford, Illinois, United States, 61104
|Illinois CancerCare-Spring Valley
|Spring Valley, Illinois, United States, 61362
|Memorial Medical Center
|Springfield, Illinois, United States, 62781
|Carle Cancer Center
|Urbana, Illinois, United States, 61801
|United States, Indiana
|Franciscan Saint Francis Health-Beech Grove
|Beech Grove, Indiana, United States, 46107
|Elkhart Clinic
|Elkhart, Indiana, United States, 46514-2098
|Michiana Hematology Oncology PC-Elkhart
|Elkhart, Indiana, United States, 46514
|Elkhart General Hospital
|Elkhart, Indiana, United States, 46515
|Radiation Oncology Associates PC
|Fort Wayne, Indiana, United States, 46804
|Fort Wayne Medical Oncology and Hematology Inc-Parkview
|Fort Wayne, Indiana, United States, 46845
|Franciscan Health Indianapolis
|Indianapolis, Indiana, United States, 46237
|Community Howard Regional Health
|Kokomo, Indiana, United States, 46904
|IU Health La Porte Hospital
|La Porte, Indiana, United States, 46350
|Premier Oncology Hematology Associates
|Merrillville, Indiana, United States, 46410
|Michiana Hematology Oncology PC-Mishawaka
|Mishawaka, Indiana, United States, 46545
|Saint Joseph Regional Medical Center-Mishawaka
|Mishawaka, Indiana, United States, 46545
|Michiana Hematology Oncology PC-Plymouth
|Plymouth, Indiana, United States, 46563
|Reid Health
|Richmond, Indiana, United States, 47374
|Memorial Hospital of South Bend
|South Bend, Indiana, United States, 46601
|Michiana Hematology Oncology PC-South Bend
|South Bend, Indiana, United States, 46601
|South Bend Clinic
|South Bend, Indiana, United States, 46617
|Northern Indiana Cancer Research Consortium
|South Bend, Indiana, United States, 46628
|Michiana Hematology Oncology PC-Westville
|Westville, Indiana, United States, 46391
|United States, Iowa
|University of Iowa Healthcare Cancer Services Quad Cities
|Bettendorf, Iowa, United States, 52722
|Physicians' Clinic of Iowa PC
|Cedar Rapids, Iowa, United States, 52402
|Saint Luke's Hospital
|Cedar Rapids, Iowa, United States, 52402
|Mercy Hospital
|Cedar Rapids, Iowa, United States, 52403
|Oncology Associates at Mercy Medical Center
|Cedar Rapids, Iowa, United States, 52403
|Medical Oncology and Hematology Associates-West Des Moines
|Clive, Iowa, United States, 50325
|Mercy Cancer Center-West Lakes
|Clive, Iowa, United States, 50325
|Iowa Methodist Medical Center
|Des Moines, Iowa, United States, 50309
|Iowa-Wide Oncology Research Coalition NCORP
|Des Moines, Iowa, United States, 50309
|Medical Oncology and Hematology Associates-Des Moines
|Des Moines, Iowa, United States, 50309
|Medical Oncology and Hematology Associates-Laurel
|Des Moines, Iowa, United States, 50314
|Mercy Medical Center - Des Moines
|Des Moines, Iowa, United States, 50314
|Iowa Lutheran Hospital
|Des Moines, Iowa, United States, 50316
|University of Iowa/Holden Comprehensive Cancer Center
|Iowa City, Iowa, United States, 52242
|Iowa City VA Healthcare System
|Iowa City, Iowa, United States, 52246
|Siouxland Regional Cancer Center
|Sioux City, Iowa, United States, 51101
|Mercy Medical Center-Sioux City
|Sioux City, Iowa, United States, 51104
|Saint Luke's Regional Medical Center
|Sioux City, Iowa, United States, 51104
|Methodist West Hospital
|West Des Moines, Iowa, United States, 50266-7700
|Mercy Medical Center-West Lakes
|West Des Moines, Iowa, United States, 50266
|United States, Kansas
|Providence Medical Center
|Kansas City, Kansas, United States, 66112
|Menorah Medical Center
|Overland Park, Kansas, United States, 66209
|Saint Luke's South Hospital
|Overland Park, Kansas, United States, 66213
|Kansas City NCI Community Oncology Research Program
|Prairie Village, Kansas, United States, 66208
|Shawnee Mission Medical Center-KCCC
|Shawnee Mission, Kansas, United States, 66204
|Cotton O'Neil Cancer Center / Stormont Vail Health
|Topeka, Kansas, United States, 66606
|United States, Kentucky
|University of Kentucky/Markey Cancer Center
|Lexington, Kentucky, United States, 40536
|United States, Louisiana
|Mary Bird Perkins Cancer Center
|Baton Rouge, Louisiana, United States, 70809
|University Health-Conway
|Monroe, Louisiana, United States, 71202
|Louisiana State University Health Science Center
|New Orleans, Louisiana, United States, 70112
|University Medical Center New Orleans
|New Orleans, Louisiana, United States, 70112
|Louisiana State University Health Sciences Center Shreveport
|Shreveport, Louisiana, United States, 71103
|Highland Clinic
|Shreveport, Louisiana, United States, 71105
|United States, Maine
|Harold Alfond Center for Cancer Care
|Augusta, Maine, United States, 04330
|Eastern Maine Medical Center
|Bangor, Maine, United States, 04401
|United States, Maryland
|Greater Baltimore Medical Center
|Baltimore, Maryland, United States, 21204
|MedStar Franklin Square Medical Center/Weinberg Cancer Institute
|Baltimore, Maryland, United States, 21237
|Johns Hopkins University/Sidney Kimmel Cancer Center
|Baltimore, Maryland, United States, 21287
|Walter Reed National Military Medical Center
|Bethesda, Maryland, United States, 20889-5600
|Union Hospital of Cecil County
|Elkton, Maryland, United States, 21921
|United States, Massachusetts
|Brigham and Women's Hospital
|Boston, Massachusetts, United States, 02115
|Dana-Farber Cancer Institute
|Boston, Massachusetts, United States, 02215
|Steward Saint Elizabeth's Medical Center
|Brighton, Massachusetts, United States, 02135
|Lahey Hospital and Medical Center
|Burlington, Massachusetts, United States, 01805
|Berkshire Hematology Oncology PC
|Pittsfield, Massachusetts, United States, 01201
|Baystate Medical Center
|Springfield, Massachusetts, United States, 01199
|University of Massachusetts Medical School
|Worcester, Massachusetts, United States, 01655
|United States, Michigan
|Bixby Medical Center
|Adrian, Michigan, United States, 49221
|Hickman Cancer Center
|Adrian, Michigan, United States, 49221
|Bronson Battle Creek
|Battle Creek, Michigan, United States, 49017
|McLaren Cancer Institute-Bay City
|Bay City, Michigan, United States, 48706
|Spectrum Health Big Rapids Hospital
|Big Rapids, Michigan, United States, 49307
|Wayne State University/Karmanos Cancer Institute
|Detroit, Michigan, United States, 48201
|Henry Ford Hospital
|Detroit, Michigan, United States, 48202
|Green Bay Oncology - Escanaba
|Escanaba, Michigan, United States, 49829
|McLaren Cancer Institute-Flint
|Flint, Michigan, United States, 48532
|Singh and Arora Hematology Oncology PC
|Flint, Michigan, United States, 48532
|Cancer Research Consortium of West Michigan NCORP
|Grand Rapids, Michigan, United States, 49503
|Mercy Health Saint Mary's
|Grand Rapids, Michigan, United States, 49503
|Spectrum Health at Butterworth Campus
|Grand Rapids, Michigan, United States, 49503
|Green Bay Oncology - Iron Mountain
|Iron Mountain, Michigan, United States, 49801
|Bronson Methodist Hospital
|Kalamazoo, Michigan, United States, 49007
|West Michigan Cancer Center
|Kalamazoo, Michigan, United States, 49007
|Borgess Medical Center
|Kalamazoo, Michigan, United States, 49048
|McLaren Cancer Institute-Lapeer Region
|Lapeer, Michigan, United States, 48446
|Mercy Memorial Hospital
|Monroe, Michigan, United States, 48162
|Toledo Clinic Cancer Centers-Monroe
|Monroe, Michigan, United States, 48162
|McLaren Cancer Institute-Macomb
|Mount Clemens, Michigan, United States, 48043
|Mercy Health Mercy Campus
|Muskegon, Michigan, United States, 49444
|Lakeland Hospital Niles
|Niles, Michigan, United States, 49120
|McLaren Cancer Institute-Northern Michigan
|Petoskey, Michigan, United States, 49770
|Spectrum Health Reed City Hospital
|Reed City, Michigan, United States, 49677
|Lakeland Medical Center Saint Joseph
|Saint Joseph, Michigan, United States, 49085
|Marie Yeager Cancer Center
|Saint Joseph, Michigan, United States, 49085
|Munson Medical Center
|Traverse City, Michigan, United States, 49684
|Metro Health Hospital
|Wyoming, Michigan, United States, 49519
|United States, Minnesota
|Medini, Eitan MD (UIA Investigator)
|Alexandria, Minnesota, United States, 56308
|Fairview Ridges Hospital
|Burnsville, Minnesota, United States, 55337
|Mercy Hospital
|Coon Rapids, Minnesota, United States, 55433
|Fairview-Southdale Hospital
|Edina, Minnesota, United States, 55435
|Unity Hospital
|Fridley, Minnesota, United States, 55432
|Hutchinson Area Health Care
|Hutchinson, Minnesota, United States, 55350
|Minnesota Oncology Hematology PA-Maplewood
|Maplewood, Minnesota, United States, 55109
|Saint John's Hospital - Healtheast
|Maplewood, Minnesota, United States, 55109
|Abbott-Northwestern Hospital
|Minneapolis, Minnesota, United States, 55407
|Hennepin County Medical Center
|Minneapolis, Minnesota, United States, 55415
|Minneapolis Veterans Medical Center
|Minneapolis, Minnesota, United States, 55417
|New Ulm Medical Center
|New Ulm, Minnesota, United States, 56073
|North Memorial Medical Health Center
|Robbinsdale, Minnesota, United States, 55422
|Coborn Cancer Center at Saint Cloud Hospital
|Saint Cloud, Minnesota, United States, 56303
|Saint Cloud Hospital
|Saint Cloud, Minnesota, United States, 56303
|Metro Minnesota Community Oncology Research Consortium
|Saint Louis Park, Minnesota, United States, 55416
|Park Nicollet Clinic - Saint Louis Park
|Saint Louis Park, Minnesota, United States, 55416
|Regions Hospital
|Saint Paul, Minnesota, United States, 55101
|United Hospital
|Saint Paul, Minnesota, United States, 55102
|Saint Francis Regional Medical Center
|Shakopee, Minnesota, United States, 55379
|Lakeview Hospital
|Stillwater, Minnesota, United States, 55082
|Ridgeview Medical Center
|Waconia, Minnesota, United States, 55387
|Rice Memorial Hospital
|Willmar, Minnesota, United States, 56201
|Minnesota Oncology Hematology PA-Woodbury
|Woodbury, Minnesota, United States, 55125
|United States, Mississippi
|University of Mississippi Medical Center
|Jackson, Mississippi, United States, 39216
|United States, Missouri
|Central Care Cancer Center - Bolivar
|Bolivar, Missouri, United States, 65613
|Cox Cancer Center Branson
|Branson, Missouri, United States, 65616
|Saint Francis Medical Center
|Cape Girardeau, Missouri, United States, 63703
|Southeast Cancer Center
|Cape Girardeau, Missouri, United States, 63703
|Saint Luke's Hospital
|Chesterfield, Missouri, United States, 63017
|University of Missouri - Ellis Fischel
|Columbia, Missouri, United States, 65212
|Capital Region Southwest Campus
|Jefferson City, Missouri, United States, 65109
|Freeman Health System
|Joplin, Missouri, United States, 64804
|Mercy Hospital Joplin
|Joplin, Missouri, United States, 64804
|Truman Medical Center
|Kansas City, Missouri, United States, 64108
|Saint Luke's Hospital of Kansas City
|Kansas City, Missouri, United States, 64111
|Saint Joseph Health Center
|Kansas City, Missouri, United States, 64114
|North Kansas City Hospital
|Kansas City, Missouri, United States, 64116
|Heartland Hematology and Oncology Associates Incorporated
|Kansas City, Missouri, United States, 64118
|Research Medical Center
|Kansas City, Missouri, United States, 64132
|Saint Luke's East - Lee's Summit
|Lee's Summit, Missouri, United States, 64086
|Liberty Radiation Oncology Center
|Liberty, Missouri, United States, 64068
|Delbert Day Cancer Institute at PCRMC
|Rolla, Missouri, United States, 65401
|Mercy Clinic-Rolla-Cancer and Hematology
|Rolla, Missouri, United States, 65401
|Heartland Regional Medical Center
|Saint Joseph, Missouri, United States, 64507
|Saint Joseph Oncology Inc
|Saint Joseph, Missouri, United States, 64507
|Saint Louis Cancer and Breast Institute-South City
|Saint Louis, Missouri, United States, 63109
|Washington University School of Medicine
|Saint Louis, Missouri, United States, 63110
|Missouri Baptist Medical Center
|Saint Louis, Missouri, United States, 63131
|Comprehensive Cancer Care PC
|Saint Louis, Missouri, United States, 63141
|Mercy Hospital Saint Louis
|Saint Louis, Missouri, United States, 63141
|Saint Louis-Cape Girardeau CCOP
|Saint Louis, Missouri, United States, 63141
|Cancer Research for the Ozarks NCORP
|Springfield, Missouri, United States, 65804
|Mercy Hospital Springfield
|Springfield, Missouri, United States, 65804
|CoxHealth South Hospital
|Springfield, Missouri, United States, 65807
|United States, Montana
|Billings Clinic Cancer Center
|Billings, Montana, United States, 59101
|Saint Vincent Healthcare
|Billings, Montana, United States, 59101
|Montana Cancer Consortium NCORP
|Billings, Montana, United States, 59102
|Saint Vincent Frontier Cancer Center
|Billings, Montana, United States, 59102
|Bozeman Deaconess Hospital
|Bozeman, Montana, United States, 59715
|Saint James Community Hospital and Cancer Treatment Center
|Butte, Montana, United States, 59701
|Benefis Healthcare- Sletten Cancer Institute
|Great Falls, Montana, United States, 59405
|Big Sky Oncology
|Great Falls, Montana, United States, 59405
|Great Falls Clinic
|Great Falls, Montana, United States, 59405
|Northern Montana Hospital
|Havre, Montana, United States, 59501
|Saint Peter's Community Hospital
|Helena, Montana, United States, 59601
|Glacier Oncology PLLC
|Kalispell, Montana, United States, 59901
|Kalispell Medical Oncology
|Kalispell, Montana, United States, 59901
|Kalispell Regional Medical Center
|Kalispell, Montana, United States, 59901
|Montana Cancer Specialists
|Missoula, Montana, United States, 59802
|Saint Patrick Hospital - Community Hospital
|Missoula, Montana, United States, 59802
|United States, Nebraska
|CHI Health Saint Francis
|Grand Island, Nebraska, United States, 68803
|CHI Health Good Samaritan
|Kearney, Nebraska, United States, 68847
|Great Plains Health Callahan Cancer Center
|North Platte, Nebraska, United States, 69101
|University of Nebraska Medical Center
|Omaha, Nebraska, United States, 68198
|United States, Nevada
|University Medical Center of Southern Nevada
|Las Vegas, Nevada, United States, 89102
|Nevada Cancer Research Foundation CCOP
|Las Vegas, Nevada, United States, 89106
|United States, New Jersey
|Cooper Hospital University Medical Center
|Camden, New Jersey, United States, 08103
|Virtua Memorial
|Mount Holly, New Jersey, United States, 08060
|Virtua Voorhees
|Voorhees, New Jersey, United States, 08043
|United States, New York
|Veterans Affairs Western New York Health Care System-Buffalo
|Buffalo, New York, United States, 14215
|Hematology Oncology Associates of Central New York-East Syracuse
|East Syracuse, New York, United States, 13057
|Glens Falls Hospital
|Glens Falls, New York, United States, 12801
|Orange Regional Medical Center
|Middletown, New York, United States, 10940
|Weill Medical College of Cornell University
|New York, New York, United States, 10065
|Staten Island University Hospital
|Staten Island, New York, United States, 10305
|State University of New York Upstate Medical University
|Syracuse, New York, United States, 13210
|United States, North Carolina
|Mission Hospital Inc-Memorial Campus
|Asheville, North Carolina, United States, 28801
|UNC Lineberger Comprehensive Cancer Center
|Chapel Hill, North Carolina, United States, 27599
|Carolinas HealthCare System NorthEast
|Concord, North Carolina, United States, 28025
|Duke University Medical Center
|Durham, North Carolina, United States, 27710
|Wayne Memorial Hospital
|Goldsboro, North Carolina, United States, 27534
|Margaret R Pardee Memorial Hospital
|Hendersonville, North Carolina, United States, 28791
|Vidant Oncology-Kinston
|Kinston, North Carolina, United States, 28501
|Marion L Shepard Cancer Center at Vidant Beaufort Hospital
|Washington, North Carolina, United States, 27889
|United States, North Dakota
|Mid Dakota Clinic
|Bismarck, North Dakota, United States, 58501
|Saint Alexius Medical Center
|Bismarck, North Dakota, United States, 58501
|Sanford Bismarck Medical Center
|Bismarck, North Dakota, United States, 58501
|United States, Ohio
|Summa Akron City Hospital/Cooper Cancer Center
|Akron, Ohio, United States, 44304
|Cleveland Clinic Akron General
|Akron, Ohio, United States, 44307
|Summa Barberton Hospital
|Barberton, Ohio, United States, 44203
|Toledo Clinic Cancer Centers-Bowling Green
|Bowling Green, Ohio, United States, 43402
|Mercy Medical Center
|Canton, Ohio, United States, 44708
|University of Cincinnati/Barrett Cancer Center
|Cincinnati, Ohio, United States, 45219
|North Coast Cancer Care-Clyde
|Clyde, Ohio, United States, 43410
|Ohio State University Comprehensive Cancer Center
|Columbus, Ohio, United States, 43210
|Grandview Hospital
|Dayton, Ohio, United States, 45405
|Good Samaritan Hospital - Dayton
|Dayton, Ohio, United States, 45406
|Miami Valley Hospital
|Dayton, Ohio, United States, 45409
|Samaritan North Health Center
|Dayton, Ohio, United States, 45415
|Dayton NCI Community Oncology Research Program
|Dayton, Ohio, United States, 45420
|Hematology Oncology Center Incorporated
|Elyria, Ohio, United States, 44035
|Mercy Cancer Center-Elyria
|Elyria, Ohio, United States, 44035
|Blanchard Valley Hospital
|Findlay, Ohio, United States, 45840
|Atrium Medical Center-Middletown Regional Hospital
|Franklin, Ohio, United States, 45005-1066
|Wayne Hospital
|Greenville, Ohio, United States, 45331
|Kettering Medical Center
|Kettering, Ohio, United States, 45429
|Saint Rita's Medical Center
|Lima, Ohio, United States, 45801
|Lima Memorial Hospital
|Lima, Ohio, United States, 45804
|Saint Luke's Hospital
|Maumee, Ohio, United States, 43537
|Toledo Clinic Cancer Centers-Maumee
|Maumee, Ohio, United States, 43537
|Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
|Maumee, Ohio, United States, 43537
|Fisher-Titus Medical Center
|Norwalk, Ohio, United States, 44857
|Saint Charles Hospital
|Oregon, Ohio, United States, 43616
|Toledo Clinic Cancer Centers-Oregon
|Oregon, Ohio, United States, 43616
|North Coast Cancer Care
|Sandusky, Ohio, United States, 44870
|ProMedica Flower Hospital
|Sylvania, Ohio, United States, 43560
|Mercy Hospital of Tiffin
|Tiffin, Ohio, United States, 44883
|The Toledo Hospital/Toledo Children's Hospital
|Toledo, Ohio, United States, 43606
|Saint Vincent Mercy Medical Center
|Toledo, Ohio, United States, 43608
|University of Toledo
|Toledo, Ohio, United States, 43614
|Toledo Community Hospital Oncology Program CCOP
|Toledo, Ohio, United States, 43617
|Mercy Saint Anne Hospital
|Toledo, Ohio, United States, 43623
|Toledo Clinic Cancer Centers-Toledo
|Toledo, Ohio, United States, 43623
|Upper Valley Medical Center
|Troy, Ohio, United States, 45373
|Fulton County Health Center
|Wauseon, Ohio, United States, 43567
|Clinton Memorial Hospital
|Wilmington, Ohio, United States, 45177
|Wright-Patterson Medical Center
|Wright-Patterson Air Force Base, Ohio, United States, 45433-5529
|Greene Memorial Hospital
|Xenia, Ohio, United States, 45385
|United States, Oklahoma
|Cancer Centers of Southwest Oklahoma Research
|Lawton, Oklahoma, United States, 73505
|Cancer Care Associates-Norman
|Norman, Oklahoma, United States, 73071
|University of Oklahoma Health Sciences Center
|Oklahoma City, Oklahoma, United States, 73104
|Mercy Hospital Oklahoma City
|Oklahoma City, Oklahoma, United States, 73120
|Mercy Physicians of Oklahoma-Lakeside
|Oklahoma City, Oklahoma, United States, 73120
|United States, Oregon
|Clackamas Radiation Oncology Center
|Clackamas, Oregon, United States, 97015
|Legacy Mount Hood Medical Center
|Gresham, Oregon, United States, 97030
|Providence Milwaukie Hospital
|Milwaukie, Oregon, United States, 97222
|Providence Newberg Medical Center
|Newberg, Oregon, United States, 97132
|Providence Willamette Falls Medical Center
|Oregon City, Oregon, United States, 97045
|Legacy Good Samaritan Hospital and Medical Center
|Portland, Oregon, United States, 97210
|Providence Portland Medical Center
|Portland, Oregon, United States, 97213
|Adventist Medical Center
|Portland, Oregon, United States, 97216
|Providence Saint Vincent Medical Center
|Portland, Oregon, United States, 97225
|Compass Oncology Rose Quarter
|Portland, Oregon, United States, 97227
|Kaiser Permanente Northwest
|Portland, Oregon, United States, 97227
|Legacy Emanuel Hospital and Health Center
|Portland, Oregon, United States, 97227
|Mid-Columbia Medical Center/Celilo Cancer Center
|The Dalles, Oregon, United States, 97058
|Legacy Meridian Park Hospital
|Tualatin, Oregon, United States, 97062
|United States, Pennsylvania
|Abington Memorial Hospital
|Abington, Pennsylvania, United States, 19001
|Lehigh Valley Hospital-Cedar Crest
|Allentown, Pennsylvania, United States, 18103
|Bryn Mawr Hospital
|Bryn Mawr, Pennsylvania, United States, 19010
|Butler Memorial Hospital
|Butler, Pennsylvania, United States, 16001
|Geisinger Medical Center
|Danville, Pennsylvania, United States, 17822
|Ephrata Cancer Center
|Ephrata, Pennsylvania, United States, 17522
|Geisinger Medical Center-Cancer Center Hazleton
|Hazleton, Pennsylvania, United States, 18201
|Penn State Milton S Hershey Medical Center
|Hershey, Pennsylvania, United States, 17033-0850
|Lewistown Hospital
|Lewistown, Pennsylvania, United States, 17044
|Riddle Memorial Hospital
|Media, Pennsylvania, United States, 19063
|Paoli Memorial Hospital
|Paoli, Pennsylvania, United States, 19301
|Guthrie Medical Group PC-Robert Packer Hospital
|Sayre, Pennsylvania, United States, 18840
|Hematology and Oncology Associates of North East Pennsylvania
|Scranton, Pennsylvania, United States, 18508
|Geisinger Medical Group
|State College, Pennsylvania, United States, 16801
|Mount Nittany Medical Center
|State College, Pennsylvania, United States, 16803
|Associates In Hematology Oncology PC-Upland
|Upland, Pennsylvania, United States, 19013
|Geisinger Wyoming Valley/Henry Cancer Center
|Wilkes-Barre, Pennsylvania, United States, 18711
|UPMC Susquehanna
|Williamsport, Pennsylvania, United States, 17701
|Lankenau Medical Center
|Wynnewood, Pennsylvania, United States, 19096
|Main Line Health NCORP
|Wynnewood, Pennsylvania, United States, 19096
|United States, South Carolina
|Roper Hospital
|Charleston, South Carolina, United States, 29401
|Greenville Health System Cancer Institute-Easley
|Easley, South Carolina, United States, 29640
|Saint Francis Hospital
|Greenville, South Carolina, United States, 29601
|Greenville Health System Cancer Institute-Butternut
|Greenville, South Carolina, United States, 29605
|Greenville Health System Cancer Institute-Faris
|Greenville, South Carolina, United States, 29605
|Greenville Memorial Hospital
|Greenville, South Carolina, United States, 29605
|Greenville Health System Cancer Institute-Eastside
|Greenville, South Carolina, United States, 29615
|Self Regional Healthcare
|Greenwood, South Carolina, United States, 29646
|Greenville Health System Cancer Institute-Greer
|Greer, South Carolina, United States, 29650
|Greenville Health System Cancer Institute-Seneca
|Seneca, South Carolina, United States, 29672
|Greenville Health System Cancer Institute-Spartanburg
|Spartanburg, South Carolina, United States, 29307
|United States, South Dakota
|Avera Cancer Institute
|Sioux Falls, South Dakota, United States, 57105
|Avera McKennan Hospital and University Health Center
|Sioux Falls, South Dakota, United States, 57105
|United States, Tennessee
|Wellmont Holston Valley Hospital and Medical Center
|Kingsport, Tennessee, United States, 37660
|Thompson Cancer Survival Center
|Knoxville, Tennessee, United States, 37916
|University of Tennessee - Knoxville
|Knoxville, Tennessee, United States, 37920
|United States, Utah
|Huntsman Cancer Institute/University of Utah
|Salt Lake City, Utah, United States, 84112
|United States, Vermont
|Central Vermont Medical Center/National Life Cancer Treatment
|Berlin, Vermont, United States, 05602
|University of Vermont College of Medicine
|Burlington, Vermont, United States, 05405
|White River Junction Veteran Administration Medical Center
|White River Junction, Vermont, United States, 05009
|United States, Virginia
|Fredericksburg Oncology Inc
|Fredericksburg, Virginia, United States, 22401
|Centra Lynchburg Hematology-Oncology Clinic Inc
|Lynchburg, Virginia, United States, 24501
|Southwest VA Regional Cancer Center
|Norton, Virginia, United States, 24273
|Virginia Commonwealth University/Massey Cancer Center
|Richmond, Virginia, United States, 23298
|United States, Washington
|Providence Regional Cancer System-Centralia
|Centralia, Washington, United States, 98531
|Saint Francis Hospital
|Federal Way, Washington, United States, 98003
|Saint Clare Hospital
|Lakewood, Washington, United States, 98499
|Providence - Saint Peter Hospital
|Olympia, Washington, United States, 98506-5166
|MultiCare Good Samaritan Hospital
|Puyallup, Washington, United States, 98372
|Rockwood Clinic
|Spokane, Washington, United States, 99220
|MultiCare Allenmore Hospital
|Tacoma, Washington, United States, 98405
|MultiCare Tacoma General Hospital
|Tacoma, Washington, United States, 98405
|Northwest NCI Community Oncology Research Program
|Tacoma, Washington, United States, 98405
|Saint Joseph Medical Center
|Tacoma, Washington, United States, 98405
|PeaceHealth Southwest Medical Center
|Vancouver, Washington, United States, 98664
|Compass Oncology Vancouver
|Vancouver, Washington, United States, 98684
|Legacy Salmon Creek Hospital
|Vancouver, Washington, United States, 98686
|United States, West Virginia
|West Virginia University Charleston Division
|Charleston, West Virginia, United States, 25304
|Edwards Comprehensive Cancer Center
|Huntington, West Virginia, United States, 25701
|United States, Wisconsin
|Langlade Hospital and Cancer Center
|Antigo, Wisconsin, United States, 54409
|Fox Valley Hematology and Oncology SC-Appleton
|Appleton, Wisconsin, United States, 54913
|Aurora Cancer Care-Southern Lakes VLCC
|Burlington, Wisconsin, United States, 53105
|Marshfield Clinic-Chippewa Center
|Chippewa Falls, Wisconsin, United States, 54729
|Marshfield Clinic Cancer Center at Sacred Heart
|Eau Claire, Wisconsin, United States, 54701
|Aurora Cancer Care-Franklin
|Franklin, Wisconsin, United States, 53132
|Aurora Health Care Germantown Health Center
|Germantown, Wisconsin, United States, 53022
|Aurora Cancer Care-Glendale
|Glendale, Wisconsin, United States, 53212
|Green Bay Oncology at Saint Vincent Hospital
|Green Bay, Wisconsin, United States, 54301-3526
|Saint Vincent Hospital Cancer Center Green Bay
|Green Bay, Wisconsin, United States, 54301
|Green Bay Oncology Limited at Saint Mary's Hospital
|Green Bay, Wisconsin, United States, 54303
|Saint Vincent Hospital Cancer Center at Saint Mary's
|Green Bay, Wisconsin, United States, 54303
|Aurora Cancer Care-Kenosha South
|Kenosha, Wisconsin, United States, 53142
|Gundersen Lutheran Medical Center
|La Crosse, Wisconsin, United States, 54601
|Holy Family Memorial Hospital
|Manitowoc, Wisconsin, United States, 54221
|Bay Area Medical Center
|Marinette, Wisconsin, United States, 54143
|Marshfield Clinic
|Marshfield, Wisconsin, United States, 54449
|Aurora Saint Luke's Medical Center
|Milwaukee, Wisconsin, United States, 53215
|Marshfield Clinic-Minocqua Center
|Minocqua, Wisconsin, United States, 54548
|Green Bay Oncology - Oconto Falls
|Oconto Falls, Wisconsin, United States, 54154
|Aurora Cancer Care-Racine
|Racine, Wisconsin, United States, 53406
|Ascension Saint Mary's Hospital
|Rhinelander, Wisconsin, United States, 54501
|Marshfield Clinic-Rice Lake Center
|Rice Lake, Wisconsin, United States, 54868
|HSHS Saint Nicholas Hospital
|Sheboygan, Wisconsin, United States, 53081
|Ascension Saint Michael's Hospital
|Stevens Point, Wisconsin, United States, 54481
|Green Bay Oncology - Sturgeon Bay
|Sturgeon Bay, Wisconsin, United States, 54235
|Aurora Cancer Care-Waukesha
|Waukesha, Wisconsin, United States, 53188
|Aspirus Regional Cancer Center
|Wausau, Wisconsin, United States, 54401
|Aurora Cancer Care-Milwaukee West
|Wauwatosa, Wisconsin, United States, 53226
|Diagnostic and Treatment Center
|Weston, Wisconsin, United States, 54476
|Marshfield Clinic - Weston Center
|Weston, Wisconsin, United States, 54476
|Aspirus UW Cancer Center
|Wisconsin Rapids, Wisconsin, United States, 54494
|Marshfield Clinic - Wisconsin Rapids Center
|Wisconsin Rapids, Wisconsin, United States, 54494
|United States, Wyoming
|Rocky Mountain Oncology
|Casper, Wyoming, United States, 82609
|Welch Cancer Center
|Sheridan, Wyoming, United States, 82801
|Principal Investigator:
|George Philips
|Alliance for Clinical Trials in Oncology
|Responsible Party:
|National Cancer Institute (NCI)
|ClinicalTrials.gov Identifier:
|NCT01198158 History of Changes
|Other Study ID Numbers:
NCI-2011-02603 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
CALGB 90802 ( Other Identifier: Alliance for Clinical Trials in Oncology )
CALGB-90802 ( Other Identifier: CTEP )
U10CA180821 ( U.S. NIH Grant/Contract )
U10CA031946 ( U.S. NIH Grant/Contract )
|First Posted:
|September 9, 2010 Key Record Dates
|Last Update Posted:
|September 27, 2018
|Last Verified:
|September 2018
Additional relevant MeSH terms:
Carcinoma, Renal Cell
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Kidney Neoplasms
Urologic Neoplasms
Urogenital Neoplasms
Neoplasms by Site
Kidney Diseases
Urologic Diseases
Endothelial Growth Factors
Antibodies, Monoclonal
Immunoglobulin G
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
Growth Substances
Physiological Effects of Drugs
Growth Inhibitors
Antineoplastic Agents
Immunologic Factors
Immunosuppressive Agents
Anti-Bacterial Agents
Anti-Infective Agents


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Increased expectations for linear motion products industry, robotics
Recent news that Foxconn plans to increase automation in the company's Chinese factories has increased expectations of the market for linear motion products and linear and torque motors. These are important components and sub-assemblies in machinery used in electronics production, and are widely used in automated industrial machinery in general.
Two recently published reports by IMS Research found that the electronics machinery sector accounted for nearly 9% of the linear and torque motor market and over 6% of the linear motion market in 2010.
Foxconn's intended increase in the number of industrial robots in its Chinese factories, from 10,000 currently, to 300,000 in 2012 and 1 million by 2013, will provide an immediate boost to manufacturers of industrial automation machinery. It is also an indicator of a wider trend.
According to The United States Bureau of Labor Statistics, the hourly compensation costs in manufacturing for China increased from US $0.62 in 2003 to US $1.36 in 2008. Estimates indicate the hourly rate reached US $1.98 per hour in 2010. In February 2011 it was reported that Wuhan, capital city of Hubei province China, held eight job fairs in one day. More than 80% of enterprises in Wuhan have raised salaries to attract workers. It is expected that as labor costs increase in China, investments in automated machinery will also increase.
Increases in factory automation in Chinese factories in all industry sectors, will drive growth in the world market for linear motion products and for linear and torque motors for many years to come. The World Market for Linear Motion Products considers in detail how this and other trends will affect the development of this market up to 2015.
IMS Research
Foxconn Technology Group
– Edited by Chris Vavra, Control Engineering, www.controleng.com


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Presupuesto ₹1500-12500 INR
drawing for a story books for the kids
12 freelancers están ofertando el promedio de ₹7488 para este trabajo
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Hannibull - Follow Da Flo [Unsigned Hype]
"HOT97NY/BIG DAWG PITBULL "THE FINISHER" MISTER CEE and DJ 50 Grand (discovered NOTORIUS BIG) introduces HANNIBULL- Follow Da Flo mixtape performance video of "FOLLOW DA FLO" from OUTTA DA CAGE: RELOADED available for download at FIREMIXTAPES.com. CONTACT: email@example.com
**TAGS : HANNIBULL, HOT97, FOLLOW DA FLO, DJ Mister Cee, DJ 50 Grand, ReelRood**"
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Connect Hearing Thunder Bay
947 Memorial Ave
Thunder Bay, ON, P7B 4A1
Toll Free: (888)501-2661
The Connect Hearing clinic in Thunder Bay is located at the set of lights between Lakehead Motors and Value Village, in the small office building with the Connect Hearing banner out front.
Submit the form at the right or call us today to schedule a complimentary hearing screening. It's quick, easy and will confirm the health of your hearing. If your test reveals that you would benefit from hearing aids, a qualified professional will make a recommendation, with no cost or obligation.
We accept ADP, WSIB and VAC.
We are currently accepting new clients. No physician referral is required.
There are so many reasons to connect:
- Free, no-obligation hearing aid demo
- Complimentary hearing evaluation for clients aged 50+
- Price Match Guarantee
- Advantage Payment Plan
- Soundcare Assurance aftercare program
- Exclusive benefits for CAA Members
- Save up to 15% on hearing aids
- 5 years of free batteries with hearing aid purchase
- Save 15% on Everyday Listening Products
- Best offer guarantee
* Private clients only. Cannot be combined with any other offer, rebate or previous purchase and is non-redeemable for cash. Lyric, BAHA and econoaids excluded. ®CAA and CAA logo trademarks owned by, and use is granted by, the Canadian Automobile Association. ™ CAA Rewards is used by the Canadian Automobile Association.


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|An easy find out by Utah Lake (note the GPS )
KBYU was right what I needed at the time to soothe me during the sadness of my empty nest depression.
It showed a bunch of people from all walks of life who hunted with their GPS systems for caches that were hidden all over the world. Caches that are hidden in plain sight! But- camouflaged from everyday folks. Well what do you know, a game I can play anywhere in the world for free? I am a really good seeker of things; I just seem have a gift for finding things. Just ask my mom, I always used to know where she hid her crap. So as I went to the website Geocaching.com and I began to do my homework.
- First, I registered for free on the website.
- Second, I typed in my zip code
- Third, I dropped my jaw at the sheer amount of caches just on the west side of Provo.
- Fourth, I went to get my first cache at the Walkers just around the corner from our house.
It has all been so much fun since that first cache. I bought myself a really great GPS unit dedicated to geocaching. All I have to do is log on to the website and then I download the caches I want to seek out. Since August 10, 2011 I have found over 40 caches and have hidden 13 of my own in various places all around the city. This is an activity that I plan to stick with for many years. Some of the benefits are exercise, good company*my daughter Jordan loves it*, and learning so much about the areas I visit. I cannot think of a better family activity. I only wish I knew about this activity when we lived overseas. I could have really logged some great caches then. I guess I will just have to start over and go back to revisit those places again!


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About Us...
Chos Black Belt Academy is located in Fond Du Lac, WI. at 331 Winnebago Dr. (N.E. corner of Harborview Plaza) 920-922-9401, and in Ripon, WI. at 404 Eureka St. 920-748-3481.
Cho's Black Belt Academy is headed by Supreme Grandmaster Instructor Byung Kon Cho who is a 9th. degree black belt in tae kwon do. What is a Supreme Grandmaster? A Supreme Grandmaster is a master who has been a ninth degree black belt for 10-years or more.
Cho started training in Soul Korea at age 10. He later trained soldiers to get ready to go to Viet Nam. He them moved to the U.S.A. and started a school in Green Bay, WI. Cho is the founder of the Universal Martial Arts Association and is a leader in the Moo Duk Kwan style of Tae Kwon Do.
Check out Grand Master Cho's website at http://www.cbbatkd.com.
Cho's Black Belt Academy of Fond du Lac and Ripon, WI. is run by Grandmaster Instructor Paul Benish who is a 7th. degree black belt in Tae Kwon Do. Paul is a member of the World Tae Kwon Do Federation, the International Tae Kwon Do Federation, and the Universal Martial Arts Federation. Paul has been an instructor since 1989. His youngest student to get a black belt was 7 1/2 years old, and his oldest student to get a black belt was 75 years old.
Cho's of Green Bay is run by Master Dale McDermid who is a 6th. degree black belt in Tae Kwon Do.
We are committed to providing quality martial arts instruction to each and every student. We teach the traditional Moo Duk Kwan style of Tae Kwon Do. This is the first style of Tae Kwon Do that was started after Korea broke free of the occupation of Japan. We also teach Skillz Dynamic Martial Arts Training to ages 3-14.
The Lil'dragons classes are for kids ages 3 & 4 at the Fond du Lac and the Ripon locations. In these classes we concentrate on teaching your child the Early Skillz Program with age appropriate skills such as kicking, punching, blocking, crawling, hopping, rolling, running, and catching. The classes are on Tuesday at the Fond du Lac school, and on Monday at the Ripon school. You can do this class for only $45.00 per month.
Our tae kwon do classes are divided into age specific groups to work on the skillz that children and adults need.
*Our Basic Skillz Program is for ages 5 & 6.
*Our Core Skillz Program is for ages 7 to 11.
*Our Extreme Skillz Program is for ages 12 & up.
To find out more about our Skillz Programs click on Skillz Dynamic Martial Arts Training at the top of this page.
Adult Taekwondo classes:
Our adult taekwondo classes will get you in great shape because of the cardio, strength training, and flexibility exercises that are involved in our classes. You will also learn self-defense techniques, and sparring. We also offer weapons training.
Our Taekwondo oath:
1. I shall observe the tenets of Tae Kwon Do.
2. I shall respect my instructors and seniors.
3. I shall never misuse Taekwondo.
4. I shall be a champion of freedom and justice.
5. I shall build a more peaceful world.
Taekwondo Tenets:
1. Courtesy
2. Integrity
3. Perserverance
4. Self control
5. Indomitable spirit
Please click on classes for our class schedule for both schools.
*We have a class for every member of your family!
*Weapons class at our Black Belt Club Classes on Friday nights.
Knife defense
* For a free introductory week of classes and class prices please call Fond du Lac 920-922-9401, Ripon 920-748-3481, or text us at 920-960-2707.


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Lexus Group VP and General Manager Mark Templin reveals the 2014 Lexus IS Sport Sedans at the Detroit auto show. (Video)
Copyright Notice
All materials on this site are for editorial use only. The use of these materials for advertising, marketing or any other commercial purpose is prohibited. They may be cropped but not otherwise modified. To download these materials, you must agree to abide by these terms.


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NEW YORK (BP) -- Raised in the South Bronx neighborhood of Mott Haven, Shamar Smith is no stranger to the lifestyle and perils that mark the lives of many in the neighborhood; his own brother is already serving out a sentence on Rikers Island, New York's primary jail complex. Had Smith not found his safe haven through Graffiti 2 Community Ministries, his path might have looked the same.
A high school student, Smith has attended the ministries' after-school program for years. "Without Graffiti 2, without Andrew," he said, "… I don't know where I might have ended up."
Many of the children and families Andrew Mann, pastor and director of Graffiti 2 Community Ministries, works with every day have similar stories. Since Mann opened the church and community center doors in 2005, he has seen tremendous growth and influence in Mott Haven.
When Mann planted the church he was the sole staff member. Now it has grown into a beloved part of the community, and includes six full-time staff members (seven counting Proof, Mann's beloved therapy dog). The staff all relocated to the area from other parts of the U.S. after serving short-term alongside Mann. Together they host daily after-school programs and tutoring for more than 60 children and teenagers, a weekly fellowship meal and Bible study every Thursday, monthly life skill classes, mentoring programs for teenagers, special outreach events and camps and weekly Sunday services. All of it is designed to reach the families of Mott Haven for Christ.
"We're a family program," Mann explains. "We work hard to empower the families we serve as a whole. That's really God's mission for our ministry."
Mann's sense of God's mission is what has kept him living in Mott Haven for nearly a decade. The area is home to some 90,000 people -- 30,000 of whom are under the age of 18 and subject to a number of risk factors for future struggles including poor education, gang violence and instability in the home. Despite these hurdles, Mann says there is a real strength to the neighborhood.
"There is a strong sense of the value of neighborhood here and a deep rooted community. We may face difficult circumstances in Mott Haven, but God is always working."
Mann is one of six missionaries featured this year by the North American Mission Board (NAMB) as part of its 2014 Annie Armstrong Easter Offering promotion. New York City, where Mann serves, is one of 32 Send North America cities NAMB is bringing special emphasis and resources to in its effort to help Southern Baptists start 15,000 new churches in 10 years. Half of NAMB's financial support comes from the Annie offering.
Mann moved to Mott Haven from suburban Missouri after serving alongside missionary Taylor Field and his team at Graffiti in Manhattan. He connected with the church while attending New York University to pursue a degree in music. He quickly jumped in, joining the music team his second Sunday in attendance. However, Mann soon made the decision to transfer to Wheaton College in Illinois. That decision took him out of the city and away from the ministry of Graffiti. Even still, Mann says God was preparing his heart for his return to the city one day.
"Every step was preparing me for my eventual move to Mott Haven," Mann says. "When I transferred to Wheaton I started serving in Humboldt Park, a tough part of the Chicago area. God was slowly growing in me a heart for neighborhoods like this -- neighborhoods like Mott Haven."
Mann continued to spend time alongside Field and his team at Graffiti, serving two summers with them before Field asked the recently graduated Mann to consider leading the launch of a second campus for Graffiti in the Bronx.
"I spent some time prayerwalking through Mott Haven after Taylor asked me about launching Graffiti 2. Walking those streets, I really felt a sense of calling to the people there. In that moment I believe God gave me a promise -- if I would be obedient to His call to Mott Haven, He would take care of my needs."
And since the launch of Graffiti 2, God has been faithful to that promise, Mann says. The workload for him and his team is heavy, each one taking on a number of responsibilities to keep the church growing and thriving. Mann does everything from leading worship band practice and Bible studies to preaching Sunday services and mentoring and tutoring students after school each day.
The relationships Mann and his team have built in the community have helped the ministry at Graffiti 2 to flourish. Their dedication to the community didn't miss a beat last year when Mann was diagnosed with cancer. The ministry soldiered on as Mann endured two major surgeries and months of chemotherapy, taking him in and out of work repeatedly over the course of the year. Now cancer free and back to work full time, Mann says the experience reminded him of God's faithfulness to not just him but to the people of Mott Haven as well.
"I'm still trying to process all that God showed me during that year, but I know one thing: God is faithful. He called me to Mott Haven, but with or without me, God will continue working to see this community changed in His name because He loves these people even more than I do."
The support of Southern Baptists and the Annie Armstrong Easter Offering has also given Mann a great sense of encouragement throughout his ministry but in particular through the last year.
"I appreciate so much the prayers of our network of churches in the Southern Baptist Convention," Mann says. "The generosity and support they've shown our ministry has empowered us to press on in the work God has called us to do in Mott Haven."
For more on Andrew Mann and his ministry at Graffiti 2 Community Ministries, visit graffiti2ministries.org. To view a video on Andrew Mann's ministry, visit www.anniearmstrong.com.
Sara Shelton writes for the North American Mission Board.
Copyright (c) 2014 Southern Baptist Convention, Baptist Press www.BPNews.net


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The pomegranate is one of those fruits that is a little mysterious and sometimes hard to find - but did you know it's actually been cultivated for thousands of years.
On the health side, pomegranates explode with fiber, vitamins, nutrients, flavonoids (which, in some studies, are known to be anti-inflammatory), and phytochemicals.
This month, Covenant Care facilities will be cooking up a variety of recipes using apples, as well as creating displays to educate our staff, residents and families. The kitchen will incorporate pomegranates in some creative ways, from salads, sauces, sparkling drinks and more. This is all part of the Enhanced Dining services which includes the "Dietitians Healthy Pick of the Month".
< Back to Catered Manor Nursing Center News & Events
Catered Manor Nursing Center
4010 Virginia Road
Long Beach, CA 90807
Phone: (562) 426-0394
Fax: (562) 424-1529
Covenant Care was founded in 1994 by healthcare professionals who wanted to create a company that
would exceed customer expectations through quality care. We strive to provide complex, comprehensive and compassionate care in a safe and comfortable environment. Learn More >
Covenant Care Announces 2015 Chairman's Award Winner Read More >
Covenant Care Rolls Out "Enhanced Dining" Read More >
27071 Aliso Creek Road, Suite 100
Aliso Viejo, California 92656


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Salisbury seniors Jake Latamondeer and Austin Francis, along with sophomore Keegan Wyatt all scored two touchdowns Friday as part of the Panthers 49-6 football win against Paris that spoiled the Coyotes' Senior Night.
The win allowed Salisbury to claim a three-way tie for the Lewis & Clark Conference football championship with Westran and Marceline as all three schools posted identical 4-1 conference records.
Class 1 7th-ranked Salisbury put up 21 points during the opening period and led 35-0 by halftime. The rest of their points were scored in the third quarter, and Paris scored a touchdown against the Salisbury jayvee unit in the final period.
For his second straight week Austin Wyatt filled in as a running back nicely for Salisbury (8-1). Wyatt, who was a standout wide receiver before taking over the quarterback position during the first seven weeks of the season while Francis healed from a lengthy foot injury, led the team in rushing with 92 yards on eight carries.
Latamondeer rushed nine times for 74 yards. Sophomore Daniel Linneman gained 67 rushing yards and Francis had 51 reported Salisbury football coach Kirk Stott on Monday.
Francis also completed 8 of 14 passes for 144 yards and a pair of TDs.
Tight end Alex Wilson had two receptions that netted 71 yards and a score. Keegan Wyatt caught three passes for 51 yards and a touchdown to help pave the way.
Salisbury limited Paris (3-6, 2-3 LCC) to only 84 yards of total offense in the game.
Caleb Henke led the Panthers in tackles with 11 and Brady Francis had seven. Zach Wyatt and Wilson each had an interception.
Sophomore Kyle Popkes replaced injured sr. Steven Hayhurst at quarterback and Popkes completed 7 of 18 passes for 46 yards and he threw two interceptions.
Slater Stone rushed for 41 yards on 14 carries, but justin Wolfe was thrown for a loss of 3 yards on his six carries.
Zac Baladenski had 15 tackles in the game for the Coyotes while Kole Berry and Wolfe each had 10.


text: Job Discussion Forums :: View topic - bangkok roomy Get TEFL Certified & Start Your Adventure Today! Job Discussion Forums"The Internet's Meeting Place for ESL/EFL Students and Teachers from Around the World!" FAQ Search Memberlist Usergroups Register Profile Log in to check your private messages Log in bangkok roomy Job Discussion Forums Forum Index -> Thailand View previous topic :: View next topic Author Message chidoJoined: 23 Jun 2004Posts: 2 Posted: Tue Jun 29, 2004 7:52 pm Post subject: bangkok roomy yo all. i am coming to bangkok on the 6th of july. has anyone heard of the school, Fun English? i am supposedly going to teach for them. i need a place to live. i much prefere living with other people, lots of other people so if you are looking for a roomy and wanna share rent and space with me. lemme know. becky. ps any recomendations about hoods to avoid or funky places to live in bangkok are welcome too. Back to top Display posts from previous: All Posts1 Day7 Days2 Weeks1 Month3 Months6 Months1 Year Oldest FirstNewest First Job Discussion Forums Forum Index -> Thailand All times are GMT Page 1 of 1 Jump to: Select a forum Where to Begin----------------General DiscussionNewbie ForumCurrent Events ForumTechnology ForumOnline Teaching Forum Africa Forums----------------General Africa Forum Asia Forums----------------CambodiaChina (Job-related Posts Only)China (Off-Topic)Hong KongIndiaIndonesiaJapanMalaysiaPhilippinesSingaporeTaiwanThailandGeneral Asia ForumVietnam Caribbean Forums----------------General Caribbean Forum Europe Forums----------------Czech RepublicFranceGermanyGreeceItalyMacedonia and the BalkansPolandRomaniaRussia & C.I.S.SpainTurkeyUkraineUnited KingdomGeneral Europe Forum Latin America Forums----------------ArgentinaBrazilChileColombiaCosta RicaMexicoMexico (off-topic)PeruGeneral Latin America Forum The Middle East Forums----------------BahrainEgyptIsraelKuwaitOmanQatarSaudi ArabiaUnited Arab EmiratesGeneral Middle East Forum North America Forums----------------General North America Forum Oceania----------------Australia/New Zealand You cannot post new topics in this forumYou cannot reply to topics in this forumYou cannot edit your posts in this forumYou cannot delete your posts in this forumYou cannot vote in polls in this forum This page is maintained by the one and only Dave Sperling. Contact Dave's ESL Cafe Copyright © 2018 Dave Sperling. All Rights Reserved. Powered by phpBB © 2001, 2002 phpBB Group Teaching Jobs in China


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Leigh Griffiths restored some local pride for Hibernian as he earned them a Clydesdale Bank Premier League 1-1 draw in the first Edinburgh derby since their William Hill Scottish Cup final thrashing by Hearts.
Griffiths was a constant menace and finished off a slick move 30 seconds before half-time to allow Hibs fans some respite from the taunting of the visitors to Easter Road.
Alan Maybury had earlier gifted his former club the opener on his Hibernian debut when Andrew Driver pounced on his short header back to goalkeeper Ben Williams, and Hearts stretched their unbeaten derby run to 12 games.
Copyright (c) PA Sport 2012, All Rights Reserved.


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U.S. Equal Employment
Opportunity Commission
WASHINGTON - Naomi C. Earp was sworn in today as a member of the U.S. Equal Employment Opportunity Commission (EEOC), serving in the capacity of Vice Chair, to fill the remainder of a five-year term expiring July 1, 2005. President Bush signed the recess appointment of Ms. Earp last week on April 22. Under the recess appointment, she will serve until the end of the 108th Congress unless she is confirmed by the Senate in the interim. The President nominated Ms. Earp on November 27, 2001, and again on January 9, 2003.
"Our new Vice Chair is no stranger to the Commission, having served here earlier in her career," said EEOC Chair Cari M. Dominguez today during a swearing-in ceremony at agency headquarters. "Naomi Earp brings to the agency a wealth of EEO expertise, as well as hands-on leadership and management experience. She has a strong track record in promoting diversity in both the private and federal sectors. My fellow Commissioners and I extend a warm welcome to our new Vice Chair and look forward to her contributions."
Ms. Earp's work experience in promoting diversity and EEO includes a series of progressively responsible leadership positions in the federal government with various agencies, including the National Institute of Science and Technology, the National Institute of Health, the Federal Deposit Insurance Corporation, and the U.S. Department of Agriculture. At NIH, she spearheaded the development of a world-class diversity initiative and a nationally-recognized Alternative Dispute Resolution program. Ms. Earp also served as an Attorney Advisor at the EEOC during the mid-1980s. In addition, she has worked as an independent consultant providing services to private employers and public agencies on a variety of employment-related issues and programs. Her educational background includes a law degree from Catholic University, a masters degree in education from Indiana University, and bachelor's degree from Norfolk State University.
Ms. Earp joins Chair Dominguez and Commissioners Paul Steven Miller and Leslie E. Silverman on the five-member Commission, with one seat remaining vacant. Further information about the Commission is available on its web site at www.eeoc.gov.


text: Dave's ESL Cafe's Student Discussion Forums :: View topic - Study TEFL in Cusco Dave's ESL Cafe's Student Discussion Forums"The Internet's Meeting Place for ESL/EFL Students and Teachers from Around the World!" FAQ Search Memberlist Usergroups Register Profile Log in to check your private messages Log in Study TEFL in Cusco Dave's ESL Cafe's Student Discussion Forums Forum Index -> Travel View previous topic :: View next topic Author Message mackenrroeJoined: 07 Jun 2010Posts: 1 Posted: Wed Jun 09, 2010 6:03 am Post subject: Study TEFL in Cusco hi everybody! Has anyone studied a TEFL course in Peru? Could you recommend me wich one to study? Thanks a lot, have a nice day John Back to top Display posts from previous: All Posts1 Day7 Days2 Weeks1 Month3 Months6 Months1 Year Oldest FirstNewest First Dave's ESL Cafe's Student Discussion Forums Forum Index -> Travel All times are GMT - 8 Hours Page 1 of 1 Jump to: Select a forum Student Forums----------------ComputersCurrent NewsCultureEnglish SchoolsFamilyFilm and CinemaFoodHealth and FitnessHelp CenterHobbiesHolidaysLearning EnglishLiteratureMaking FriendsMusicOpinionsPetsScienceSportsThe Strange and MysteriousTOEFL and Other English ExamsTravel You cannot post new topics in this forumYou cannot reply to topics in this forumYou cannot edit your posts in this forumYou cannot delete your posts in this forumYou cannot vote in polls in this forum Dave's ESL Cafe is maintained by the one and only Dave Sperling. Banner Advertising | Bookstore / Alta Books | FAQs | Articles | Interview with Dave Copyright © 2018 Dave's ESL Cafe | All Rights Reserved | Contact Dave's ESL Cafe | Site Map Teachers College, Columbia University: Train to Teach English Here or Abroad Powered by phpBB © 2001, 2002 phpBB Group


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Africa is a pear-shaped continent that stretches from the mid-latitudes of the Northern Hemisphere across the equator to the mid-latitudes of the Southern Hemisphere. Most would also find surprising that northern Africa is at a latitude equivalent to Norfolk, Virginia and that the southern tip is at a latitude equivalent to Buenos Aires, Argentina.
Africa is like a large, "Dagwood" climate sandwiched between a good deal of symmetry either side of the equator. The northern and southern tips have a Mediterranean climate with a cool, relatively wet winter and a sunny, warm and dry summer. This gives way quickly as you move equator-ward to hot, semi-arid or arid climates. Here you find the two of the world's most famous deserts, the Sahara and Namibia. Further equator-ward, the climates turn wetter with at least one wet season. Nearer the equator, we find a very wet tropical rain forest climate and in most places two wet seasons.
The primary cause of this mirror-image, climate layering is the seasonal movements of the Subtropical Highs of both hemispheres and the Intertropical Convergence Zones (ITCZ) that separate them.
In the winter seasons, extreme northern and southern areas of Africa find themselves poleward of the subtropical highs and vulnerable to passage of the polar front and polar cyclones. This can lead to periodic general rains and even high elevation snows along with chilly temperatures. Places where we find this happening include northern Morocco, Algiers, Tunisia, and northernmost Egypt in the Northern Hemisphere and the Cape region of South Africa in the Southern Hemisphere. During summer in these regions, the subtropical high dominates with warm and dry conditions. These conditions are typical of Mediterranean Climates.
Within regions where the subtropical highs dominate, the accompanying sinking air leads to sunshine and hot, desert dry conditions. The countries here are parts of Morocco, Egypt, Libya, Algeria, and in the Southern Hemisphere, Namibia.
In regions where the ITCZ passes, we find a distinct rainfall maximum during its passage. This usually is at the time of the highest sun. In those areas where the ITCZ reaches just once a year, we find a single rainfall maximum. The fringe areas where the ITCZ barely reaches (the Sudan, the Sahel Belt countries of Mali, Upper Volta, Niger and Chad)) are the most vulnerable to drought and famine when the ITCZ is weak and out of position. Further equator-ward, the rainfall during the wet season is more dependable and heavier. Countries like Gambia, Sierra Leone, Senegal, Ghana and Guinea get relatively heavy rainfall during the Northern Hemisphere summer with disturbances that swirl along the tropical convergence zone. These tropical waves spin out into the Atlantic where they can become tropical storms or hurricanes.
Closer to the equator, in places like southern Cameroon, Zaire, the Congo, Gabon, Liberia, the Ivory Coast, Rwanda, Kenya and Uganda, the ITCZ passes twice. As a result, these areas have a dual rainfall maximum.
Temperatures vary considerably across the continent, especially in winter. For example, in the north, in the winter, temperatures may drop below freezing and, in the extreme, even below zero. The continent's all-time record low was a surprising -11°F (February 11, 1935 at Ifrane at 5,364 feet elevation in Morocco). Closer to the equator, temperatures may reach 110°F in winter, which is the dry season. In between, in the desert, dry air means an abundance of sunshine and a large diurnal (day to night) temperature variation.
In summer, the Sahara experiences excessive heat. El Azizia in Libya reached 136°F on September 13, 1922. In areas and seasons where rainfall occurs, the temperatures are less extreme, but very high humidity makes the air extremely uncomfortable.
The Namibia desert in southwest Africa is much less hot than the Sahara in the north thanks to the cooling effect of the Benguela Current, which flows offshore.
Higher elevations also have cooler temperatures. Nairobi near the equator in the Kenya Highlands is a good example. Highest recorded temperature there has been just 87°F. Johannesburg over a mile high in the high veld in South Africa has a relatively pleasant and healthy climate. The area is subject to cold temperatures during winter nights due to the high elevation and relatively high latitude (26 degrees South) and dry air.