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Posted By Kurt Schlichter On August 8, 2011 @ 4:38 am In 2012 Budget, 2012 Election, Congress, Featured Story, Federal Spending, Politics, Tea Party | 45 Comments
It's already happening – the liberal dream of a perpetual social welfare state where deadbeat liberal constituencies feed off of the work of productive conservative citizens in perpetuity is dying. There's no doubt about that; the only question left is how long and hard the process will be as the hideous leviathan the utopian liberal establishment has created convulses and dies.
It's going to die hard. And ugly.
The collapse is well-underway in Europe – Greece has gone from the cradle of democracy to a cesspool of union-fueled mobs – but America faces the same trauma. As the contradictions inherent in the vision [1] of a societal plan based on the notion that an ever-expanding pool of Democratic-voting serfs sucking the wealth away from the mostly Republican-oriented producers who labored to create it become more apparent, the reactions and rear-guard efforts of the terminal liberal elite will grow more extreme.
We are already seeing the liberal elite lash out in anger and frustration at what is a perfect storm of failure. Glenn Reynolds, the legendary Instapundit [2], chronicles the daily disintegration, while the brilliant Mark Steyn's cheery new book, After America: Get Ready for Armageddon [3], drops on August 8, 2011 – I'll race you to Amazon to get a copy.
As the three components of the liberal establishment – the media, the unions and politicians – rage at the dying [4] of the liberal light, the insanity meter will swing far into the red. It's already begun. The Tea Party has dared to speak the truth, and the uncomfortable realities it has pointed out have destroyed the bogus consensus that has allowed the debt Titanic to sail giddily on toward the iceberg. That's why the establishment response is to demonize the popular movement. We're "terrorists" or "lunatics" or, bizarrely, "hobbits." Our crime is telling the truth.
Never mind that the Tea Party candidates were absolutely clear about their debt crisis solution when running for election – the voters spoke. Apparently, the only polls that matter get taken around the tables at Manhattan and Georgetown dinner parties – and, oddly, the results are always unanimous in favor of a "compromise" that tries to shore-up the crumbling status quo.
The problem with the Tea Party is not what it does – at best, right now, it can only make a moral and political case; it does not have the numbers to make anything happen without non-Tea Partiers joining it. The problem with the Tea Partiers, in the eyes of the liberal establishment and the pet moderate GOP enablers, is that it dares to point out the indisputable truth that must be hidden at all costs: That the social welfare state is unsustainable and will collapse.
But the demonization campaign does not seem to be working as expected – amazingly, the Tea Party caucus was able to provide the missing spine to the go-along/get-along gang running the House and present a primary-based incentive to the collegial Senate Republicans who have to face the voters next year and don't want to join booted squish ex-Utah senator Bob Bennett in his new sinecure as the MSM's go-to, slam-the-conservatives, pseudo-GOP nobody. While the resulting deal was terrible, it was still a massive humiliation for the liberal establishment. They are not in a forgiving mood, and it's easier to hate on the Tea Party than face the fact that they've driven us to bankruptcy.
So when demonization doesn't work, government lifers like Senator Kerry advocate silencing the opposition [5]. One might think that a United States senator demanding that the media refuse to report the views of his political opponents because too many people are accepting them might stir some outrage in the media. But then, if you did, you probably might believe in unicorns, leprechauns and global warming as well.
Instead of a chorus of outrage at this creepy fascism, the media elite seem to think this is a great idea. But that should not be a surprise. The media – at least the old media (call it the MSM) – is dying, killed off not only by technology that allows conservatives to evade the gates it used to defend to prevent the political discourse from being contaminated with ideas that challenge its foundational liberal premises [6]. It is grasping at a life preserver, trying to take in a few more lungfuls of air before it sinks under forever.
With the establishment politicians far "out of their depth [7]" in response to the coming crisis, watch for more moves by the Left not to resolve the situation but to kill the messenger. Do not put it past the elite to actually try again to limit debate using law and/or regulations. They still salivate at the notion of killing off conservative radio by resurrecting the Orwellian Fairness Doctrine [8], and the government at one point argued that it had the right to criminally prosecute citizens for publishing a book critical of politicians [9] until it backed down. Note that the MSM strongly supports these forays into fascism – not surprising since they think that the Constitution that allows conservatives' voice to be heard is a "problem." [10]
But it will be impossible to regulate conservative opposition out of existence – not just because of the First Amendment but because the coming reckoning will be so severe that it can no longer be swept under the rug. Yet, rug sweeping will become their next strategy. Playing off the demonization tactics, they will continue to attempt to engage moderate – read "squishy" – Republicans toward some sort of "compromise" that will give them just a bit more time before everything comes crashing down. Watch for this when the "Super Commission" comes back with its plan. Their goal – get past November 2012 then hopefully use the crisis to their advantage to turn the ship of state even harder to port.
But that's a fool's errand. The DC establishment can ignore math, but math won't ignore it. There is simply not enough wealth that exists or can be imagined into existence through borrowing to support the redistributionist utopia they seek. Greece is a harbinger of the future. The EU will cobble together a bogus bailout that will keep the Hellenic rowboat afloat just a bit longer before it is swamped, but Zorba best learn to swim because it is going under.
Then the other failed states of Europe – Ireland, Spain, Italy, Portugal – will collapse too, taking with them Europe's banks and our banks along with them. The only reason we won't fail first – S&P did not act too early but, rather, far too late in downgrading the US – is that Europe's social democratic elite is even more delusional than ours.
It's over. The system must crash and reboot. The choice is a hard landing or a harder landing.
The prescription is clear to anyone looking at the situation, except for the establishment that will not see it because to admit what must be done and embrace it means to wave goodbye to its members' power, prestige and position. We need to slash spending to less than the revenue we take in – the difference going to pay off the $14 trillion-plus tab. And we need to do it now, not in some hazy future where some other Congress will have to make the tough calls – though reality may just make them for it.
That means a radical return to Constitutional government where the federal government goes back to what it was formed to do – those things set forth in the Constitution and nothing else. The relatively easy part will be zeroing out the cowboy poetry slams, largely unwatched government TV networks and creepy shrimp-on-a-treadmill study grants. [11]
The hard part is the entitlements all of us were promised and none of us will ever see. It means repealing Obamacare, but moreover returning the responsibility for health care to where it belongs – the individual. The same with retirement – Social Security is a ponzi scheme and everyone knows it.
Government student loans, farms subsidies, corporate bailouts, food stamps, Section 8 housing – none of these are federal responsibilities. These should be eliminated not only because they are counterproductive, ineffective and soul-crushing for recipients but because if we don't do it on our own terms fiscal reality will do it for us cold turkey. And let's not forget eliminating vast swaths of federal regulations – something that will both free up business and have the added benefit of dumping hundreds of thousands of government loafers off of Uncle Sam's payroll.
There is a major change coming, and it could get ugly. Union members will do their masters' bidding with the support of the MSM, threatening violence and maybe committing some. Look for well-planned and carefully-coordinated "spontaneous" mass marches on public buildings by scores of public employee union slugs demanding we keep subsidizing their retirements at full pay at age 50.
Fortunately, again as observed by Glenn Reynolds [12], the present crop of union activists aren't the hardscrabble blue collar bruisers of the storied past. Today, most seem to be skinny green tea-sipping public school teachers, naggy Department of Weights & Measures diversity officers, or massive welfare-dispensing office drones clad in form-fitting purple size-XXXXL SEIU t-shirts that were made in China. Not exactly a fearsome crew, unless you're between them and a muffin.
The Tea Party did not cause what will be a brutal reckoning. It only pointed out the truth and said, "No more" – an unforgivable crime to the people who caused this disaster and want to keep milking the system for as long as possible. The key to getting through the coming trauma – and it will be traumatic, as the social contract the liberals unilaterally imposed is rewritten by an implacable reality – is for the productive citizens of the United States to stand firm and stand fast. In other words, just the way Americans have gotten through every other crisis we've faced before.
America's greatest days need not be in the past. Guided by the Founder's vision and the principles of the Constitution, we will find that they lie ahead, over just one more hill.
Article printed from Big Government: http://biggovernment.com
URL to article: http://biggovernment.com/kschlichter/2011/08/08/anticipating-the-coming-convulsions-as-the-welfare-state-dies/
URLs in this post:
[1] contradictions inherent in the vision: http://www.telegraph.co.uk/comment/columnists/janetdaley/8685945/If-we-are-to-survive-the-looming-catastrophe-we-need-to-face-the-truth.html
[2] Instapundit: http://pajamasmedia.com/instapundit/
[3] After America: Get Ready for Armageddon: http://www.amazon.com/gp/product/1596981008/ref=pd_lpo_k2_dp_sr_1?pf_rd_p=486539851&pf_rd_s=lpo-top-stripe-1&pf_rd_t=201&pf_rd_i=0895260786&pf_rd_m=ATVPDKIKX0DER&pf_rd_r=10WMQX340X23NMF037HT
[4] rage at the dying: http://www.americanthinker.com/2011/08/raging_at_the_dying_of_their_light.html
[5] advocate silencing the opposition: http://www.realclearpolitics.com/video/2011/08/05/john_kerry_media_has_responsibility_to_not_give_equal_time_to_tea_party.html
[6] foundational liberal premises: http://biggovernment.com/kschlichter/2011/08/05/keeping-on-the-offense-more-lessons-for-our-side/
[7] out of their depth: http://blogs.telegraph.co.uk/news/peteroborne/100099792/in-this-grave-crisis-the-worlds-leaders-are-terrifyingly-out-of-their-depth/
[8] Fairness Doctrine: http://online.wsj.com/article/SB123508978035028163.html
[9] criminally prosecute citizens for publishing a book critical of politicians: http://www.campaignfreedom.org/blog/detail/kagan-campaign-finance-and-banning-books
[10] they think that the Constitution that allows conservatives' voice to be heard is a "problem.": http://newsbusters.org/blogs/noel-sheppard/2011/08/07/cokie-roberts-problem-we-have-here-constitution-united-states-america
[11] creepy shrimp-on-a-treadmill study grants.: http://www.oregonlive.com/news/index.ssf/2008/11/treadmillrunning_shrimp_is_a_y.html
[12] as observed by Glenn Reynolds: http://washingtonexaminer.com/opinion/columnists/2011/06/sunday-reflection-hard-get-good-goons-these-days#ixzz1OPX3VnrI
[13] Image: #


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Return To www.bpclips.com Front Page!
Remember, any credit you buy can be used on all bpclips.com and www.bpclips.com studios!
Cheyenne is talking at the phone with her boyfriend, on the couch. We can see some good close up of her soles in nylon pantyhose.
She hears a noise outside the living room and this makes her scared. She goes to the bedroom and asks if anybody is there. Bella is hidden behind the door and wears a pair of black leather gloves. She grabs Cheyenne from behind and puts a chloro cloth over her mouth and nose. Cheyenne struggles and makes muffled screams. Bella tells her she is the sandwoman. The substance makes her weaker and she passes out after one minute of action.
Bella starts playing with limp body of Cheyenne. She fondles it, takes off her bra and squeezes her breasts. When Cheyenne wakes up, she puts her both gloved hands over her mouth and nose, smothering her. Then she takes the chloro cloth and puts it over her face. Another struggle until faint scene.
Bella plays with limp body again and waits her awakening. She handsmothers her with a gloved hand, then she puts her to sleep with the third chloroform inhalation.
The limp body play ends and Bella decides to finish all games. She takes a piece of cellophane and puts it over Cheyenne's head. This makes her very scared and she tries to remove it. Bella has no mercy and keeps it tight, until her death.

subset: commoncrawl


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ANTIQUE 14K GOLD VICTORIAN EDWARDIAN AQUAMARINE RING GENUINE GEMSTONE ice blue. About Aquamarine - History and Introduction. Aquamarine is a blue to green-blue gem-quality variety of beryl. The beryl group of gemstones is most famous for chromium-rich green emerald, one of the'precious four' gems (diamond, sapphire and ruby are the remaining three). Aquamarine is an official birthstone for those born in March.
Aquamarine is exceptionally hard and has an outstanding vitreous glass-like luster. It is most famous for its breathtaking sea-blue colors which can range from pale light blue to medium-dark blue. The name'aquamarine' was derived from an old Latin expression which meant'seawater'.
Aquamarine and emerald belong to the same family, but they are surprisingly different. Aquamarine and emerald are both beryllium aluminum silicates, but emerald is colored by trace amounts of chromium (and sometimes vanadium), while aquamarine obtains its color from iron impurities within colorless beryl (goshenite). Aquamarine and emerald have essentially the same specific gravity and refractive index, but emerald tends to be hazy and full of inclusions, while aquamarine is known to occur with excellent transparency and clarity.Aquamarines name comes from the Latin for seawater and it was said to calm waves and keep sailors safe at sea. Marchs birthstone was also thought to enhance the happiness of marriages. The best gems combine high clarity with limpid transparency and blue to slightly greenish blue hues. Like many beryls, aquamarine forms large crystals suitable for sizable fashioned gems and carvings. The name aquamarine is derived from two Latin words: aqua, meaning water, and marina, meaning of the sea. It has been said that the mineral beryl gives the wearer protection against foes in battle or litigation. It makes the wearer unconquerable and amiable, and also quickens the intellect. Aquamarine is the birthstone for March. The item "ANTIQUE 14K GOLD VICTORIAN EDWARDIAN AQUAMARINE RING GENUINE GEMSTONE ice blue" is in sale since Thursday, November 09, 2017. This item is in the category "Jewelry & Watches\Vintage & Antique Jewelry\Fine\Victorian, Edwardian 1837-1910\Rings". The seller is "4744366" and is located in Andover, Massachusetts. This item can be shipped to United States.


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Don't be afraid to lift your head
"Keep your head down" might be the worst swing advice ever. Staying down and keeping the body quiet on a pitch leads to an arms-only swing and trouble controlling contact (below, left). Instead, feel as if you're getting taller through impact as you keep turning (below, right). It'll help you use the bounce and control the swing's low point.


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Treatment of Children With Acute Promyelocytic Leukemia (APL)
Treatment of acute promyelocytic leukemia (APL), the M3 subtype of acute myeloid leukemia (AML), differs from the usual AML treatment. This leukemia usually responds well to treatment, which is given in 3 phases:
- Induction
- Consolidation (also called intensification)
- Maintenance
Many children with APL have bleeding and blood-clotting issues at the time APL is diagnosed, which can cause serious problems during early treatment. Because of this, children with APL must be treated carefully and are often given an anticoagulant ("blood thinner") to help prevent or treat these problems.
Children with APL get a non-chemotherapy drug similar to vitamin A called all-trans retinoic acid (ATRA). ATRA alone can often put APL into remission, but combining it with chemotherapy (usually daunorubicin and cytarabine) gives better long-term results. APL rarely spreads to the brain or spinal cord, so intrathecal chemotherapy is usually not needed.
Along with the possible side effects from the chemotherapy drugs, ATRA can cause a problem called differentiation syndrome (formerly known as retinoic acid syndrome). This can include breathing problems from fluid buildup in the lungs, low blood pressure, kidney damage, and severe fluid buildup elsewhere in the body. It can often be treated by stopping the ATRA for a while and giving a steroid such as dexamethasone.
Consolidation (intensification)
This is usually similar to induction, using both ATRA and chemotherapy (daunorubicin, sometimes along with cytarabine). Because of the success of this treatment, a stem cell transplant is not usually advised as long as the leukemia stays in remission.
Children with APL may get maintenance therapy with ATRA (often with the chemo drugs methotrexate and 6-mercaptopurine) for about a year.
Relapsed APL
If the leukemia comes back after treatment, most often it can be put into a second remission. Arsenic trioxide is a drug that is very effective in this setting, although it can sometimes cause problems with heart rhythms. Children getting this drug need to have their blood mineral levels watched closely. ATRA plus chemotherapy may be another option. A stem cell transplant may be considered once a second remission is achieved.
Last Medical Review: April 17, 2015 Last Revised: February 3, 2016
American Cancer Society medical information is copyrighted material. For reprint requests, please see our Content Usage Policy.
Treating Childhood Leukemia
- Immediate Treatment for Childhood Leukemia
- Surgery for Childhood Leukemia
- Radiation Therapy for Childhood Leukemia
- Chemotherapy for Childhood Leukemia
- Targeted Therapy for Childhood Leukemia
- Immunotherapy for Childhood Leukemia
- High-dose Chemotherapy and Stem Cell Transplant for Childhood Leukemia
- Treatment of Children With Acute Lymphocytic Leukemia (ALL)
- Treatment of Children With Acute Myelogenous Leukemia (AML)
- Treatment of Children With Acute Promyelocytic Leukemia (APL)
- Treatment of Children With Juvenile Myelomonocytic Leukemia (JMML)
- Treatment of Children With Chronic Myelogenous Leukemia (CML)


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Publication Date
This project deals with a set of ten narratives and illustrations. The narratives become progressively more difficult. Each line of the narrative has steps giving questions, substitution drills, and ideas on how to teach particular grammatical points. At the end of each narrative there is a supplementary material to be used once all of the preceding material is mastered.
Bilingual, Multilingual, and Multicultural Education | Curriculum and Instruction | Education | Teacher Education and Professional Development
Recommended Citation
Blount, Alice Raidl, "A Booklet of Narratives for the ESL Classroom" (1975). MA TESOL Collection. 17.
Included in
Bilingual, Multilingual, and Multicultural Education Commons, Curriculum and Instruction Commons, Teacher Education and Professional Development Commons


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Just entering his second and final year in Flushing, Michael Cuddyer has pulled off the ultimate magic trick, making himself disappear, much like he practiced throughout the 2015 campaign. While he limped through the 2015 season and playoffs, it is somewhat surprising he would end his career on such a down note. Not only did he vanquish himself from the Mets, he left a parting gift of his unexpected $12.5 million dollar guaranteed salary.
While there is no guarantee Alderson and the Wilpon's will immediately reinvest this money, it is know they need a bullpen arm, 5th starter to keep Wheeler's seat warm and an outfielder to either split time with Lagares or make him an excellent defensive 4th outfielder. I fully expect the Mets to re-sign Jerry Blevins, possibly Tyler Clippard, and a few minor league deal reclamation projects. Likely the 5th starter will be Bartolo Colon, but maybe save that money and see what Verrett or Montero can do on the cheap. And the reason I suggest saving the money on Colon is because the answer to many of our past and potential future problems is still lying in the wings, waiting for the right offer to strike. If you haven't figured it out yet, I am indeed speaking of Yoenis Cespedes.
Now we all learned towards the end of last season, and through the post-season, Cespedes is not the prototypical superstar that every team covets. But for 2 months he put this team on their back and took them to the playoffs. I firmly believe, if not for him, Murphy would not have put on his power display and the whole lineup who have been approached differently every step of the way. Sure, we can all point out his strikeouts in key spots, lack of hustle at times, and the first ball put in play in game 1 of the World Series, but remember, there would have been no World Series without him. He has an arm like no other, crazy speed for a guy of his build, and power that no park can contain. And if the owners happen to read this, he filled the seats (ka-ching)!
The longer Cespedes sits out on the market, the more the Mets have to be thinking the door for a return is creeping back open. After Heyward (26) just signed for below projected value, I can't see Cespedes getting what he is looking for and the Mets should ignite negotiations and put themselves on his and his agents minds immediately. If somehow they can talk Yo down from his 6-7 year wish list, I think a 5 year offer for the 30 year old slugger at 22-24 per is more than enough to garner interest in a return to Flushing. Heck, since it worked for Hayward and guys like Sabathia and Aroid, they should even offer an opt out after year 2 or 3 and raise the AAV slightly for those first couple of years, where on that scenario he would still be young enough to re-up with someone on another monster deal. And if he chose the opt-out, the Mets would free up money at a time when many of their young starters would be looking for mega deals as well.


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Principal Structural Engineer
- Recruiter
- Penguin Recruitment
- Location
- London
- Salary
- £50000 - £65000 per annum + Benefits + Bonus + Pension
- Posted
- 26 May 2018
- Closes
- 23 Jun 2018
- Ref
- Contact
- Sam Jackson
- Specialism
- Structural
- Function
- Civil Engineer, Engineer, Structural Engineer
- Job Type
- Permanent
- Level
- Principal
Principal Structural Engineer
Competitive Salary + Benefits + Bonus + Company Pension
This is a fantastic opportunity for a highly experienced Principal Structural Engineer to become a leading part of a highly respected, multi-disciplinary consultancy in London. Our client delivers a wide range of small, medium and large scale projects to numerous clients across the South East of England. Our client is undergoing a strong period of growth and as a result are looking to recruit a Principal Structural Engineer to help ensure to high quality delivery of projects, in addition to playing an important part in the company's development. Our client is looking to offer a competitive salary for this position, in addition to offering a wide range of exciting benefits and a company pension.
In order to be considered for this Principal Structural Engineer role you will:
- Hold professional membership with recognised institution (ICE/ IStrcutE)
- Possess a thorough understanding of British Standards and Eurocode
- Possess a good knowledge of AutoCAD and BIM software
- Possess experience working on large scale projects
- Possess excellent written and verbal communication skills
Key responsibilities of this Principal Structural Engineer role include:
- Play a central part in the delivery of a range of projects from inception to completion
- Aid the delivery of more junior engineers
- Assist in bid proposals
- Create, develop and maintain strong working relationships with valued clients
- Carry out structural design and analysis as required
- Contribute to the overall development of the company
In order to discuss this Principal Structural Engineer role and to discuss other roles in the BUILDING STRUCTURES sector please call SAM on 01792 365108 or alternatively please email a copy of your CV to email@example.com


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Thursday, 17 March 2011 03:47 PM
President Barack Obama said on Thursday that nuclear power was an important part of the U.S. energy future, and that while the country is bringing all resources to bear to monitor the situation in Japan, there is no risk to any U.S. territory.
He said he had asked U.S. regulators to undertake a comprehensive review of domestic nuclear plants in light of the natural disaster that has taken place in Japan.
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{The flight was packed and I'd suggest all to Website check in as the regular check in requires quite a long time.
If you're reserving vacation for kids that are travelling by itself, please Test the age restrictions established by the running provider prior to booking.
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See all FAQs May well I request a bassinet, diaper and infant meal when obtaining an toddler ticket on the net?
Tooltip about travelling being an adult. Press enter to expand. An Grownup travelling with little ones have to be above 18 years of age. For ticket bookings of much more than nine travellers, you should Make contact with your local reservations Place of work
Tooltip about scheduling reference. Press enter to grow. Your reference is a combination of 6 to seven letters and quantities. You could find it in your itinerary receipt or ticket.
We make just about every hard work to ensure the rate the thing is on Skyscanner is the price you pay back Together with the airline.
If you intend to e-book for an toddler, remember to Be sure to suggest the accompanying Grownup. Kindly restart your scheduling website and guide the Grownup and toddler with each other in a single transaction.
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Something I learnt travelling...Slovenia is beautiful! The sun setting over the gorgeous Lake Bohinj.
There is a danger this is going to sound like a CV or job application, but the things I have been lucky enough to learn on my travels have proved very useful in interviews for academic courses and in the hunt for jobs. Presenting yourself at an interview to strangers, is no different to presenting yourself to the strangers you meet when you travel. The only difference is you are probably wearing flip flops and a massive grin on your face during the latter scenario! Travel, and especially solo travel, requires you to be confident enough to talk to complete strangers about yourself in an interesting way without being overbearing or intensely annoying. Closely linked to this is the ability to listen to other people. The number of times I have been involved in conversations where people are happy to talk about themselves for hours on end without taking much (if any) interest in your thoughts or background infuriates me. And, to be honest, travel has taught me that these are the kind of people to avoid in all aspects of life. However, do not let this stop you from reaching out...striking up a conversation with a random person can be a useful tool, in the right circumstances. In work situations, I have successfully applied this principle, and have found myself talking to people who some of my colleagues were too afraid to engage with for fear of their status in the organisation, for example. The trick is to listen. I may make the mistake of assuming that life and work is like the rather flat/equal structure that exists amongst travellers, but I enjoy it and feel like I have gained a lot from it.
Travel has helped me realise I can enjoy my own company and get a lot done. The time I get to be alone to think (often in a beautiful location) is a real luxury these days. Without the distraction of other people, travelling solo (in particular) can allow you to really appreciate your destination; watching the people come and go, take in other cultures and also take pleasure in the scenery that lay before you as you look across the horizon.
Trust that intuition! It is usually right. Having put myself and having been put into a number of exciting and hair-raising situations, always go with your intuition. Travel has acted as a useful training ground for my intuition, allowing me to make some great friends, avoid some not so great people, get involved in some great activities and stay away from some not so great travel diversions. Judging the quality of a hostel at 20 paces or the best place to eat in the backstreets of Vilnius has proved so useful in everyday life. The idea that I can use my experiences to forge a positive future, based on my judgement was a fantastic revelation. I know...obvious for most people, but for me, knowing that I could decide what I wanted to do based on a number of factors was an eye-opener.
Big deal! So what! Who cares?! Having seen many different places, cultures and experiencing a fair few things during my travels, my sense of perspective has improved massively. When things get stressful at work, I sometimes have to remind myself that I do have a sense of perspective, but it is the things that I have seen on my travels that helps me remember that in the grand scheme of things nothing really matters. That deadline...yes, it is important, but so what?! If it is a day late, it is inconvenient, but ultimately no-one died and there are far more important things to worry about in life. Having seen the way that people live, work and what they have experienced, I am always mindful to count my blessings. My first trip turned me into a right hippy. I backpacked without any desire for all the possessions I owned back in the UK. After about two weeks of travelling, I could have easily given them up for my backpack full of clothes and a couple of good paperbacks. Stupidly idealistic and probably quite impractical, but what I took from that was the realisation that the 'stuff' we work so stupidly hard to accumulate to fill our homes is pretty worthless - 'mo money, mo problems' and all that! What I did miss were my family and friends. So, travel changed my perspective regarding where my priorities lie. Before that first big trip, the accumulation of financial wealth and belongings was my main objective in life. And, after that trip, I know that the only things that really matter are not fulfilling someone else's targets at work or generating cash for me to spend on a huge state-of-the-art flat screen TV or on the repayments for a new BMW, but family and the people around you. Success, for me, is not measured in material wealth, but by the relationships you cultivate and maintain with the people around you. Maybe this came to the fore during my trips, as travelling is a very people-centric activity that really helps you understand your fellow man. Ultimately though, this aspect of discovery I have made on my travels is of greatest importance to me.
So, travel...the great educator! You don't believe me?! Well, all I can say is go find out for yourself, you may be surprised what you learn.
Please feel free to comment below on any things that travel has taught you. I would love to hear your views on this!


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Thursday! Midsummer! London! Drinking! etc!
well, it's Monday morning, you're probably all mopey, so I'm going to offer you something to look forward to or something.
This Thursday is Midsummer's Eve, so it will be light til at least 10.30 hopefully. It's also my 25th birthday. So, to celebrate, I suggest Some Form of Drinking in Camden After Work. If it's sunny we can sit by the canal outside the Lloyds Bar, if it's not, we can go somewhere else. Um, yeah!
i like this idea
although i'm going to see tokyo police club in hoxton...
"Some Form of Drinking in Camden After Rehearsal"
But I will attempt to transit up to Camden, in any case.
There's a lot of birthdays this week isn't there?
Hurray for people who's parents had sex in September!
was it at all sketchy?
i mean i'm pretty sure i have, but i wouldn't want to repeat it if it's not the done thing.
I will try and attend but I have brownies and leaving drinks
for my old boss
If someone buys me drink
I'll be there. Although it seems I'll be the only one.
I'll buy you one, I suppose
I'm sure we can gather more people!
i probably can come, it just depends on what time you're out.
i'll come
but I will not be drinking. Perhaps if somebody buys me a sandwich?
jesus. Has it even began yet?
Worst Summer ever.
why, what?
why will i not be drinking? or why do i like sandwiches?
p.s i made my own sandwiches today!
I'll research some form of pagan ritual to celebrate
I'll be in Worthy Farm
but happy birthday! x
what in the farmhouse?
I was in there once and a fax came in from PAUL WELLER - PROLEFACT. Michael Eavis asked me if I liked him and I had to say 'yes'
This is a true story that I'll reel out on the Jonathan Ross SHow or something.
God yes I will - yes. I WILL DO IT.
^ this
plus i need to stop coming to london, getting drunk and making a tit of myself!
you should be carefull what you say dude
it just might happen, well, at least in two weeks, for blood brothers!
I can possibly make it
how shit am I?
I'll try and organise things so I can make it.
I might come
if I'm invited, but not if it's raining
I don't think I have anything in my diary
on said evening:
chiaroscuro (likely)
It's ok
they know about Deptford already. It's their job.
um, bump?
for anyone who wasn't here yesterday. You should totally come.
you need to find some Swedes in London
to party with - they do Midsummers for real
alcohol poisoning is obligatory
We could go to the Hawley
I'm sure some cunt from Razorlight will be cluttering up the place.
well, I was thinking there
if it's not sunny. It's actually a really nice pub, if there's no slebritees there.
I know
I do like the Hawley. It's nowhere near as much of a celeb hangout as the free shitrags would have you believe, despite the fact they now have paparazzi outside on Friday nights. Want me to pop in and book a table?


text:
Still sitting at the starting line, just waiting to take off already.
I fee like I'm stuck in a rut and my wheels are just spinning. There are SO many things and changes that I am looking forward to, and I feel like the hours on the clock are not moving. Like the pages on the calendar just aren't turning fast enough. I know that 9 months from now I'll probably look back and wonder where the time went. But for right now, it just can't move fast enough!
I'm still in the process of starting my business. It is VERY slow-going. We are always so busy, I feel like I never have enough time to work on it. I long for the day I can go on maternity leave and hopefully NOT come back. I'm so ready to be further along in my pregnancy – ready to start showing, ready to tell my bosses, ready to start buying things for baby, ready to figure out where we are going to live – will we ever buy a house? or will we rent a cheaper place? – and then get the baby's room ready.
I know all these things will come in time. I just feel like I'm right on the edge of something big and new and exciting and I just can't take off yet!


text:
Key figures
Technical and Financial Resources
Human Resources
For a "sustainable intensification" of agriculture
In the current context of population growth and limitation of arable lands and fossil resources, global food security is still a major challenge worldwide. In addition, there is an ever growing interest in and need for increasing the quantity and improving the quality of plant biomass for green chemistry and energy. Simultaneously, the limitation of natural resources, such as water and fossil resources, climate change and the importance of preserving the environment and biodiversity make the sustainability of agriculture another key challenge. Therefore, "sustainable intensification" of agriculture is crucial for the future.
Towards a more predictive biology…
Improving production and use of plants for food, feed, human health, environment or industry in a sustainable way will require creative plant biology research. Various traits associated with the genetic, physiologic and environmental controls of plant growth can have a significant impact on the sustainable intensification of plant production. In order to meet these challenges, an in-depth understanding of the underlying molecular processes and new tools for transferring this knowledge to the crop varieties used in agriculture are required. Given the inherent complexity of living organisms and the unprecedented increase in the power of analytical tools, a major challenge for biologists is the application of more mathematics and informatics to describe and model this complexity and make biology more predictive.
… by understanding the plant's basic biological mechanisms
Nevertheless, the predictive value of the knowledge relies on, and is strengthened by, the understanding of basic processes involved in the regulation of plant physiology and development. It should be noted that the development of efficient engineering tools for research and development (e.g. translation to plant breeding) and the mechanistic understanding of plant development and physiology are tightly linked.
3 scientific challenges
Therefore, taking into account the current socio-economic and scientific contexts we have identified three strategic, complementary and interconnected scientific challenges that consist of :
- moving towards a more predictive biology,
- understanding basic mechanisms that control plant development and physiology,
- developing tools and biotechnology for research, innovation and valorisation.
A state-of-the-art research moving towards innovation
To address these challenges, the strategy of the SPS network is to support the best academic research, teaching and training that is necessary for innovations over the long term and to ensure that academic excellence is accompanied by relevant thematic priorities, dissemination and valorisation of research and training activities, based on scientific and socio-economic issues.
The SPS network provides a unique opportunity to consolidate all these aspects, excellence, valorisation of the results and overall attractiveness in the area of plant sciences and biotechnology. Indeed, SPS is one of the largest consortia of research, teaching and training, focused on plant biology in Europe, with the highest impact in this field in France.


text:
Life Science
Functional Genomics & RNAi
Product Overview
We are a member and distributor of The RNAi Consortium for phase 1 and 2 (TRC1.5 and TRC2) development of human and mouse lentiviral-based shRNA libraries. The TRC1.5 shRNA collection, comprised of almost 200,000 clones targeting greater than 22,000 human and 20,000 mouse genes, is complete and clones are available as whole genome libraries, subsets categorized by gene family or pathway, or as individual clones. TRC2 is now complete. TRC2 contains more than 127,000 clones targeting more than 15,000 human genes and almost 13,000 mouse genes. There are more than 4,100 genes covered exclusively in TRC2. The TRC2 vector includes the WPRE (Woodchuck Posttranscriptional Regulatory Element), which has been shown in literature to promote RNA processing and enhance nuclear export of viral and shRNA RNA. This may lead to increased viral titers from packaging cells, and enhanced expression of the shRNA in target cells.
We are the exclusive provider of TRC clones in purified DNA and lentiviral formats for any combination of TRC clones. Bacterial glycerol stock format is also available. Click on the diagram below to find the product that best meets your needs.
General Information About MISSION® TRC shRNA Clones
Each MISSION® shRNA clone is constructed within the lentivirus plasmid vector pLKO.1-Puro or TRC2-pLKO-Puro followed by transformation into Escherichia coli. The pLKO.1–Puro and TRC2-pLKO-Puro vectors contain bacterial (ampicillin) and mammalian (puromycin) antibiotic resistance genes for selection of inserts in either bacterial or mammalian cell lines. Each gene is represented by multiple individual shRNA constructs or clones targeting different regions of the gene sequence. Therefore, a range of knockdown efficiency, with at least one construct from each gene set being >70%, can be expected when using these clones. This allows one to examine the effect of loss of gene function over a range of gene knockdown efficiencies. Each shRNA construct has been cloned and sequence verified to ensure a match to the target gene. The clones are available in frozen bacterial glycerol stock format, purified plasmid DNA format, or lentiviral transduction particle format.
As shown in the RNAi workflow and the diagram below, bacterial stocks may be used to create plasmid DNA. The plasmid DNA may either be transfected directly into your cells of interest or used to make lentiviral particles via a viral packaging process. The DNA and viral formats require less handling and reduce the number of steps to start your research. You may acquire MISSION® TRC shRNA clones in any format and start the process at the point that is most convenient to you.
Bacterial Glycerol Stock Format (SHCLNG)
Bacterial cultures may be amplified from the glycerol stocks for use in purification of shRNA plasmid DNA. Subsequently, target cell lines may be transfected with the purified plasmid for transient or stable gene silencing (puromycin selection). In addition, self-inactivating replication incompetent viral particles can be produced in packaging cells (HEK293T) by co-transfection with compatible packaging plasmids.
Individual shRNA clones are provided as a frozen bacterial glycerol stock (E. coli) containing Terrific Broth (TB), carbenicillin at 100 µg/ml and 15% glycerol.
Go to the Getting Started Page
Download the SHCLNG Technical Bulletin (171 Kb PDF)
Purified Plasmid DNA Format (SHCLND)
We offer the highest quality purified plasmid DNA for downstream transfection and lentiviral packaging. DNA purified with our 96-well DNA purification system, developed specifically for the TRC library, yields the highest quality lentiviral particles.
Purified plasmid may be directly used in transient or stable gene silencing (puromycin selection). In addition, self-inactivating replication incompetent viral particles can be produced in packaging cells (HEK293T) by co-transfection with compatible packaging plasmids.
Individual constructs are provided as frozen stocks containing 1 µg of plasmid DNA in Tris-EDTA (TE) buffer at a concentration of 20 ng/µL. See gene family set technical bulletins for specifications, inquire for library specifications.
Log in and try out our powerful MISSION® shRNA ordering interface to select the standard vector backbone or customize your shRNA by choosing an alternate vector backbone. Visit the Vector map website for details on these alternate vectors.
Go to the Getting Started Page
Download the SHCLND Technical Bulletin (149 Kb PDF)
Lentiviral Format (SHCLNV)
Self-inactivating replication incompetent viral particles are produced in packaging cells (HEK293T) by co-transfection with compatible packaging plasmids. In addition, the lentiviral transduction particles are pseudotyped with an envelope G glycoprotein from Vesicular Stomatitis Virus (VSV-G), allowing transduction of a wide variety of mammalian cells. The lentiviral transduction particles are titered via a p24 antigen ELISA assay and pg/ml of p24 are then converted to transducing units per ml using a conversion factor.
Individual constructs are provided as a 200 µL frozen stock containing a minimum of 1.0 x 106 TU/ml (via p24 assay) in Dulbecco's Modified Eagle's Medium with 10% heat-inactivated fetal bovine serum and penicillin-streptomycin. Our average titers for individual clone orders are routinely greater than 1.0 x 107 TU/ml (via p24 assay). See gene family set technical bulletins for specifications, inquire for library specifications.
Choosing Your Titer and Volume
As a logged in customer, you have the ability to customize not only the vector backbone (visit the Vector map website for details), but also the titer and volume you desire. Please refer to the table below for standard aliquotting. If you require different aliquotting, please use our custom request form.
Go to the Getting Started Page
Download the SHCLNV Technical Bulletin (181 Kb PDF)
Manufacturing Information and Shipping Timelines
Orders of 25 or fewer individual clones are provided in individual vials. Each vial contains a unique two dimensional barcode label that can be read using a corresponding reader. A printed value corresponding to The RNAi Consortium (TRC) clone number is also provided on each tube. For glycerol and DNA, orders of >25 individual clones are provided in a 96-well plate with a one dimensional barcode label on the plate. 96-well plates are provided with a USB drive containing plate map positions.
Each set of individual clones is produced on demand in our state-of-the-art manufacturing facility. The following times are required to produce each format after the order appears in our LIMS manufacturing database:
Please Note:
If your order includes customization of volume, titer, or vector, the turn-around-time will be longer than listed above.
Additionally, if your order contains >25 individual clones with vector customization, or >50 individual clones in the standard vector, the turn-around-time will be longer than listed here. We recommend contacting your local sales representative for pricing and timelines for larger orders.
Orders ship Monday through Thursday. Glycerol format orders received after 10:00 am on Wednesday may not ship until the following Monday. As indicated, some orders may require additional time to process. Please allow up to 2 weeks additional shipping time for international orders.
For questions about the library, pricing and quotes or other concerns, please e-mail us at: firstname.lastname@example.com.
MISSION is a registered trademark of Sigma-Aldrich Co. LLC Label License.
© 2019 Merck KGaA, Darmstadt, Germany and/or its affiliates. 保留所有权利。严格禁止在未经同意的情况下转载本网站之所有信息。 Sigma-Aldrich品牌产品均由Sigma-Aldrich LLC.独家贩售。的注册商标。沪ICP备14038167号-2.
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text:
The pump that had served me for 18months has gone to retirement. It was quite accidental that day was.
I returned a bit late from lunch that fateful Tuesday 28th September 2010. So I thought, "Ok I can pump later at 3 or 4pm." But work caught up to me and I was engrossed doing something until I totally forgot about it.
The next day, I was busy too at work and afterwards I went out with my colleagues. It was close to 10pm when Tufeil finally drank from me. And I didn't feel anything with regards to soreness or what.
Even before these two days, I had been tweeting my thoughts, "Why the hell am i still pumping at work when Tufeil absolutely refuses to drink expressed Breastmilk?" Back then, I didn't wanna stop still cause I was afraid I might feel lost at work without anything "extra" to do. In honesty, it was a 20min reprieve from work.
But after those 2 days of lapses, I felt lazier and lazier and never touched my pump since! But I left the equipment here in the office. Just in case.
You know how I feel about it now? Liberated. I feel FREEEEEEEEEEEEEEEEEEEEE. hahaha
I had been planning to go to the gym during lunch time. But now the previous gym-going boss has left the company, I'm not sure what's the view of this new guy. PLUS, its gonna cost me $90 per month, so I'm still stalling.
But the next thing to look forward to is to totally wean him from Breastmilk so I can start taking slimming pills or whatever ya know.
By the way, I saw Desperate Hosuewives Season 2 Epi 15 or so a few nights ago and there was this lady who was BFing her 5 year old and claimed that she could still eat a lot of donuts and maintain a slim figure because of it. Well i say BS! It didn't work for me after 12 months! The moment Tufeil turned 1 year old, I started to steadily gain more and more weight till now I feel like a balloon. I feel worse when I look at pictures of my slim self from a year ago. T_T
The Pump Has Retired
The pump that had served me for 18months has gone to retirement. It was quite accidental that day was.
4 glasses of Juice:
- The 6 of Us said...
Congrats on regaining ur freedom hehe ;-) But cherish the closeness during BF and co-sleeping, 'cos when they grow bigger and become more independent, cuddles and hugs are not easy to come by.
- Fri Oct 08, 09:06:00 AM 2010
yah manz. i will miss that too. *sobs* my bm is slowly depleting too now that sarah is turning 2.
- Fri Oct 15, 04:23:00 PM 2010
- Jussaemon said...
Kak Nor, how do you now the supply is depleting? I mean can u actually feel it? For me, i think mine's not much either but T just continue to, u know, suckle for comfort?
- Mon Oct 18, 10:55:00 AM 2010
- Jussaemon said...
Kak R, Hmmm yes I should heed what you said after all, You're more experienced than me!
- Mon Oct 18, 10:56:00 AM 2010


text: So the notes I read from the keynote only mentioned backlighting with the 2.4Ghz model. The "tech specs" listed on Apple's site do not list backlighting for the 2.0Ghz model, but do list it for the 2.4Ghz model. However, when I go to order a 2.0Ghz, it clearly shows "Backlit keyboard" as standard. It isn't an option (although you can pick between english or spanish). I checked both the Canada and US store and both give backlit as standard. Who is right? If I order online, will I get backlit? Is it some sort of online thing only? Am I going to get hosed when I go to the Apple store tomorrow to buy a standard model and it doesn't come with backlighting?


text: Brain Control in colour. I've been taking the time to adjust some black and white drawing into colour with Photoshop, deleting the black and replacing it with colour. Just a bit of technology practice instead of watching walking dead! Advertisements Share this:TwitterFacebookLike this:Like Loading... Related This entry was posted in Illustration and tagged #illustration #paolo fiore illustration, Illustration, photoshop. Bookmark the permalink.


text:
proofread/copyedit my article
Bajet $10-30 USD
I'm a writer and I want a native English speaker to help me proofread and copyedit my work. Thanks.
The article attached is only about 2000 words, so should be an easy job.
19 pekerja bebas membida secara purata $34 untuk pekerjaan ini
I take grammar and spelling very seriously, and am always willing to proofread or edit any material needed.
hi my name is mark, the photo is real and i am who i represent to be (happy to prove everything) i about me, i have a Juris Doctor law qualification from Australia and a Masters of Education and Linguistics, I also com Lagi
Hi There, I can provide top quality proofreading/copyediting to attached 2000 words article fulfilling all the requirements. I'm a NATIVE ENGLISH Speaker with 8+ years of experience in writing on various niches. Hav Lagi
I have worked as an instructional designer, technical writer, and writing instructor. I've written, edited, and proofread a wide variety of content for over 20 years. I am well versed in using library data bases, inte Lagi
Hi there. I have a first-class degree in English Literature so I can assure you I can proofread and edit your article to a high standard of English. I'm also very responsive so feel free to message me if you have any q Lagi
Dear client I am readily available to proofread and copy edit your content. I am a skilled proofreader, please contact me at the soonest. Thanks
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Superior level of English, passionate writer myself. Edited many documents in science fields. Would be great to work with you in a long term relationship


text:
Proposed salary hike doesn't satisfy SC officials
The parliament endorsed a proposal to hike the salary of judges working in all three tiers of courts, but the Supreme Court officials said they are not happy with the proposed hike. They said the hike is less than what they had proposed.The proposal on Some Acts Amendment Bill Relating to Judges' Remuneration, Condition of Service and Facilities was sent to the parliamentary Law, Justice and Parliamentary Affairs Committee for a clause-wise discussion.The bill, tabled by Minister for Law, Justice and Parliamentary Affairs Narendra Bikram Nembang, has proposed salary hikes for Chief Justice and judges of all three tiers of courts.The government proposed Rs 31,800 as monthly salary of the CJ along with allowances, and Rs 25,800 as monthly salary of Supreme Court justices and allowances, but Supreme Court officials feel the proposed hike is not enough.If the proposal is passed, an appellate court chief judge will get 24,300 and judges will get 22,800 as monthly salary.
District court judges will get 18,800 as monthly salary. The judges will get housing allowance, petrol allowance, telephone and electricity allowance, and newspaper allowance. During official visits, they will get daily allowances.However, Supreme Court officials feel that the proposed increment is different from the Supreme Court's suggestion that was forwarded to the government before July. "Our recommendation was a bit different from the government's proposal," spokesperson for the SC Til Prasad Shrestha told . The SC had forwarded its suggestion before the increase in the salary of civil servants."The bill does not even uphold the spirit of the constitution that bars deduction in facilities enjoyed by judges," he added. According to him, the bill violated the constitution while fixing new housing allowance.The judges have been enjoying half-month salary as housing allowance. The new proposal has proposed giving judges less than a half-month's salary as housing allowance. "The proposed salary is comparatively higher than that of civil servants, but the state should provide enough salary to the judges so they will be committed to their duty," president of the Supreme Court Bar Association, Prakash Raut, said. "The justices should be empowered by every means to make sure their judgement is not affected.""The bill does not even uphold the spirit of the constitution that bars deduction in facilities enjoyed by judges."
Monday, December 03, 2007
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text:
Billionaire's Ex Files Racketeering Claim
(CN) – The ex-wife of one of America's richest men sued her former husband in New York, saying billionaire hedge fund manager Steven Cohen used fraud to hide millions from her during their divorce. Patricia Cohen says her ex, with a reported net worth of $6.4 billion, made a lot of his money from insider trading.
Steven Cohen's firm, SAC Capital Advisors, which is also named as a defendant, has about $14 billion under management, according to published reports.
All told, he owns or controls at least 25 domestic and of-shore entities, which Business Week has described as a "highly secretive and stupendously successful" group of funds.
Patricia Cohen, who married Steven Cohen in 1979 and left him 9 years later, claims her ex "consistently and systematically" defrauded her through repeated acts of mail and wire fraud. She seeks at least $100 million.
Patricia Cohen says she discovered her former husband may have been concealing assets after he was profiled by "60 Minutes" in March 2006. Subsequent investigation revealed more unflattering media profiles – including a Fortune profile that described Gruntal, a firm with which her husband was affiliated, as a "den of corruption" – and also revealed bank accounts, mortgage holdings, real estate transactions and deals that Cohen had not disclosed, Patricia Cohen says.
She says her ex-husband's fraudulent concealment of activities, which ranged from compelled testimony before the U.S. Securities and Exchange Commission to multimillion-dollar investments in co-op apartments in Queens, was "consistent with a pattern of highly secretive conduct that has long characterized his business and personal affairs."
As recently as Dec. 4, Reuters reported that "SAC places a premium on secrecy" and that defendant "Cohen is so intensely private he hates being photographed and has even brought the rights to some pictures taken by freelancers."
The SEC summoned Cohen to explain profitable trades he made before General Electric bought RCA in early 1986. During that testimony, Cohen declined to answer many questions, citing the Fifth Amendment, according to the complaint.
But Patricia Cohen said her husband told her of the pending deal in late 1985. She says he told her that he wasn't engaging in insider trading because while he knew the inside source of the information was a Wharton classmate, he received the tip he acted on from an intermediary.
Patricia Cohen claims that a financial statement her ex-husband provided to the court during their divorce proceedings in 1988 "was materially false and misleading," that it failed to disclose a bank account in Miami and the activities of hedge funds he controlled.
She says an affidavit Steven Cohen filed as divorce proceedings continued into 1991 was also false and misleading.
Named as defendants are SAC Trading Corp. SAC Capital Management Inc.; SAC Capital Management LP; SAC Capital Management LLC, SAC Capital Associates LLC, Sigma Capital Management LLC; and Cohen's brother, Donald.
Patricia Cohen is represented by Paul Batista of New York.


text:
Greg Berlanti, co-producer and co-writer of the upcoming Green Lantern movie, has given some updates on Warner Bros./DC Comic film, Flash movie. Berlanti has said that while Green Lantern might be lighter in the tone of the film, they want the Flash to be darker and be placed some where between Green Lantern and Dark Knight. They want the sci-fi & crime component of the film to work well by borrowing elements from Se7en and Silence of the Lambs. Also, they want the film to feel "real" which is where elements from The Matrix will help them in that department. Another reveal was that this Flash will be the Barry Allen character, just in case you were wondering.
What do y'all think of this news? Is this the kind of Flash movie you want or do you think they will screw it up in some way. Personally, I think this may be an interesting take on the Flash character and might create interest for some folks who originally didn't care for the speedy superhero. Tell us what you think by leaving a comment.
Source: GeekTyrant


text:
Reading / Re-reading.
Travels With My Aunt - Graham Greene
I'm only halfway through this, but I'm loving it so far. Very well written, with characters you'd love to meet.
The Tarot Cafe Part 1 - Sang-Sun Park
It's more of a graphic novel, featuring four little stories of supernatural characters dealing with love and loss. It's very nicely drawn, and it's a sweet little book.
Millions of Women are Waiting to Meet You - Sean Thomas
Hmmm. This book confuses me. This is the story of a single man who tries internet dating. There are two parts to the story - the current events and the past events. The current bits are reasonably funny, and can hold my interest. The flashbacks... well, he seems to find it necessary to graphically talk about all the amazing sex he's had in the past, as if he's concerned we'll think he's unmanly for dating online. Now, you know me, I'm happy to talk or read about sex. But, if I'm to be honest, it just got very, very tedious.
The Man in the Rubber Mask - Robert Llewellyn
Very funny, with a lot of background and behind-the-scenes looks at what it's like to play 1/4 of the Red Dwarf cast.
Colony - Rob Grant
A darkly funny read from one of the writers of Red Dwarf.
Is it Just Me, Or is Everything Shit? Volume 2 - Steve Lowe and Alan McArthur
The perfect book for a grumpy person like myself. It's one of those books that have you laughing out loud and reading snippets to people. The first one's good, too.
After the Funeral - Agatha Christie
One of my favourite Poirot mysteries.
The Lovely Bones - Alice Sebold
I'm never sure about this book. On one hand, this is about the third or fourth time I've read it, and I like parts of it, but I'm not sure that it deserves the hype it got when it came out.
The Children of Green Knowe - Lucy M. Boston
A child's classic. I loved the Green Knowe series of books when I was a child. They're so magical and haunting.


text:
4 Initiatives for 2018's Most Influential CFOs
According to a detailed three-part survey of CFOs conducted by Ernst and Young*, CFO's feel now, more than ever before that there are four different initiatives or tasks they must perform in order to be effective. The importance of each of these four had become a higher priority compared to just three years earlier.
Five Reasons to be THANKFUL for A/P Automation
November is the month for reflection and Thanksgiving. When considering your day-to-day routines, are you thankful for your company's Accounts Payable functions? Are you set up with systems that leave behind manually-labor-intensive and expensive processes? Today's A/P best practices are definitely something many can be thankful for this holiday season.
Must-Attend 2017 Conferences for Financial Professionals- Part 2
Are you a CFO, Controller, CIO or Accounts Payable Manager? Are you interested in making plans for attending educational or other conferences later this year? Here you will find a list of conferences from around the nation that offer opportunities to explore, discover, and widen the scope of your financial knowledge.
Breaking Through the Barriers to Accounts Payable Automation
With the proliferation of automation in Manufacturing, Human Resources and Sales & Marketing, do you think your peers within your company would be surprised to learn that your Accounts Payable department still writes paper checks to suppliers and vendors? Would your family and friends think that working where you do that accounts payable systems must certainly be automated?
accounts payable automation solutions website here


text:
Degree Type
Degree Name
Bachelor of Science in Business Administration (BSBA)
Date Information
May 2016
Accounting and Finance
First Advisor
Lillian Little
Do women's choice in apparel, hair, makeup, and overall appearance have an impact in the way they are perceived in the world of business? In careers that are predominantly male, are women not taken seriously based on how they look? We challenge the idea that a woman can't be attractive, confident, and smart. With research taken from academic journals and prominent magazines, we explore whether or not there is a gender barrier in the workplace. The findings are geared towards young women entering the business world so they can be better prepared for the scene of a male-dominated field.
Recommended Citation
Salazar, Beatriz Alexandra, "These Heels Were Made For Working: Women's Appearance in the Workplace" (2016). Honors Theses. 119.


text:
Macroautophagy is an evolutionarily conserved catabolic mechanism that delivers intracellular constituents to lysosomes using autophagosomes. To achieve degradation, lysosomes must fuse with closed autophagosomes. We previously reported that the soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) protein syntaxin (STX) 17 translocates to autophagosomes to mediate fusion with lysosomes. In this study, we report an additional mechanism. We found that autophagosome–lysosome fusion is retained to some extent even in STX17 knockout (KO) HeLa cells. By screening other human SNAREs, we identified YKT6 as a novel autophagosomal SNARE protein. Depletion of YKT6 inhibited autophagosome–lysosome fusion partially in wild-type and completely in STX17 KO cells, suggesting that YKT6 and STX17 are independently required for fusion. YKT6 formed a SNARE complex with SNAP29 and lysosomal STX7, both of which are required for autophagosomal fusion. Recruitment of YKT6 to autophagosomes depends on its N-terminal longin domain but not on the C-terminal palmitoylation and farnesylation that are essential for its Golgi localization. These findings suggest that two independent SNARE complexes mediate autophagosome–lysosome fusion.
- Submitted: 12 December 2017
- Revision received 1 April 2018
- Accepted: 7 May 2018
This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
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text:
Three ads are currently getting the proverbial goat:
Firstly, the ads warning us about how to spot if someone is having a stroke. All worthy of course, but if they scare a (wussy, admittedly) 35 year old six-footer like me, then God knows what they do to kids watching.
Secondly, the Thomson ads featuring Welcome To My World by Jim Reeves. I love that song, and their edited version makes a mockery of its meaning, structure and rhyme, and really irritates me. Here's the proper version...
Thirdly, the anti-speeding advert, featuring the dead child everywhere the man turns. Don't ever let anyone live with a mistake, will you? And it can't do much for the drivers who knocked down children when they weren't speeding ... sometimes the pedestrian is at fault too, y'know...
10 March 2009
I've ad enough
Authored by Matthew Rudd
2 comments:
- Callum said...
Can I also suggest the one for bloody Saclà pasta sauce? Stupid annoying percussionistic vanity-accented twattery.
And of course the Lloyd's Bank (AKA HM Taxpayer) ones with that creepy theme tune and the little cartoon folk getting on a train.
One thing to be thankful: Parships.co.uk has stopped adertising on telly.
- 10/3/09 10:54 pm
- Charles Nove said...
"Sausages? Leave it out!"
This appallingly written piece of tat is propping up undersold breaks all over the place and it makes me M A D !
- 12/3/09 12:32 am
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Auto Repair: Tips To Keep Your Car In Shape
You were probably not born knowing how to do any auto repairs. You must work on gaining knowledge that will help you protect your investment. Your car is a huge investment and must be cared for properly. With these tips, you will be able to relax.
Be sure to ask lots of questions when taking your car to an auto repair service. Find out what caused the issues, and ask what you can do so this does not happen again. You can save a lot of money when you know how to prevent problems.
Monitor your radiator. Run your engine for several minutes, and then turn it off and pop your hood. Don't open your radiator cap if your car is on. Use a dipstick to check the radiator's fluid level, and remember to always mix water in with your coolant if need be. Some coolants come premixed.
You might not need a mechanic to fix your car problem. You can fix some things easily. You can take your chances by going on the Internet to find some information to see if you can locate the problem. If the repair is not difficult, you can fix it yourself and save a lot of money.
A good referral makes it much easier to locate a trustworthy mechanic. Ask co-workers, friends and family for recommendations. They will be able to give you a heads up about satisfaction, quality and price. They will be the first to tell you about a dishonest mechanic too!
Keep car records handy. Some people keep this paperwork in the glove compartment of their car so it is readily available, if needed. The people repairing your automobile are going to need to look over these records. This will help to diagnose any problems.
Look at the reviews of local auto shops online. These reviews will inform you of the company's quality, customer service satisfaction rates, etc. This information is useful as you search for the right shop for your needs.
If you notice your headlights do not shine as brightly as they used to, check to make sure they are clean. The roads you drive on sometimes contain greasy residues, which can get on your lights. Therefore, this will reduce the brightness of your lights. Cleaning your lights with a glass cleaner will allow them to perform better.
Ensure that your mechanic is familiar with your vehicle's make. Though some basic components are similar, the way different models utilize space varies. If you're not sure, go to the dealership for repair.
If you have something major that needs to be done by someone at a shop, you have to be sure you get more than just a single price. Do not pay extra money for a service that can be performed at a fraction of the cost. Seek out good shops that that are reputable and familiar with your type of vehicle. Shops like this may understand your car's needs better.
Think about using a mechanic who works from home. You can usually find lower prices if you go through mechanics that are not affiliated with a franchise. You can support small business and save hundreds on the cost of the repair.
Keep an eye on the lights located on the dash, and make sure you are aware of what they all mean. They are intended to give you a warning when you need it. Ignoring these warning lights will not make the problem go away.
Keep in mind that it's not always safe to do some auto repairs. Ensure that you have help close at hand in case something goes wrong. If you buy good quality tools, they will last a long time. This is particularly true with tire changing tools. Remember that you need a jack that can hold the vehicle up especially when you need to get under it. Thus, hydraulic jacks and jack stands are important to have.
Check your tire pressure every time you fill up your gas tank. Make sure that your tires are not punctured in any way. Any problems should be fixed immediately. You don't want to take any chances by driving with weak tires.
Auto Repairs
Wouldn't you like to make your next auto repair experience a little easier than your last one? With the right information, you can enjoy better luck with auto repairs. Put this advice to get your auto repairs done today.


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|The largest independent, non-commercial, consumer-oriented resource on the Internet for owners, collectors and enthusiasts of fine wristwatches. Online since 1998.
A marketplace for chronographs, dive watches and other tool-type wristwatches and timepieces
|Please see our ChronoTrader Policies and Terms of Use.
|Learn more about How To Include Photos In Your Postings.
Rules: Postings must be an ad announcing an intent to sell, buy or trade. Full item description and photo(s) must be posted within the message here, not as links to other websites. Links to online auctions and other sites: Links to online auctions, dealer sites or other listings of items are permitted, but you should be careful to ensure that such listings will comply with our other ChronoTrader Policies. In addition, we request that sellers linking to online auctions or listings offer some benefit or accomodation to ChronoTrader readers (for example, some discount or an undertaking to end an auction early, to keep a watch "in the family"). Photos must be of the actual item for sale in its present condition. No counterfeit or replica products. No post for the same item may be repeated within 7 days, except to lower the asking price. Commercial dealers are limited to three unique posts per day. [More...]
Hi guys
Last reduction before withdrawn, now asking price for this is 3400€ including bracelet.
I think this is a total bargain considering actual market prices. Don't have much more to say. Watch is stunning IMO, truly better that other pieces sold for a lot more from famous resellers :) I can also provide videos in order to show you how great this watch is in "real life", if needed.
Let me know if interested, thank you all
|Chronocentric and zOwie site design and contents (c) Copyright 1998-2005, Derek Ziglar; Copyright 2005-2008, Jeffrey M. Stein. All rights reserved. Use of this web site constitutes acceptance of the terms of use.


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Sunday, November 6, 2011
Carnet de croquis
6 comments:
Gorgeous M!ReplyDelete
This is a wonderful vista....
If i had known you were there I'd have gladly had a glass of wine...a conversation!
I went from being very much the awkward outsider to mooching along in delight! 2 days is not enough... but yet it is more than enough to furnish one's dreams!
S x!
Thank you, Sophie! It would have been great to catch up with you—and you were certainly already in my quartier (St. Michel / Notre Dame area).ReplyDelete
La prochaine fois, alors...
I think this is a lovely watercolour sketch! looks like a beautiful place :)ReplyDelete
Thanks, Ben! Northern Italy is lovely this time of year...ReplyDelete
Yes it,s Rugolo!ReplyDelete
Thanx Maral!
Hope i can take a tour to Sarmede to see your work!
Ciao Tullio—thanks for your comment!ReplyDelete
I borrowed your book from the library just last week, the one about the ant: "Une fourmi pas comme les autres". It is so funny! Especially the ending..."PENG!"
Benvenuto nel mio blog!


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The Nigerian Football Federation is set to honor iconic goalkeeper, Vincent Enyeama as the Losc Lille shot stopper marks his one hundredth appearance for the Super Eagles.
Enyeama would win his 100th cap for Nigeria on the 26th of March when the Super Eagles take on Bolivia in Uyo, Akwa Ibom which is coincidentally, Enyeama's home state. NFF plans a special celebration to honor the goalkeeper who made his debut for Nigeria in 2002 in a match against Kenya and has gone on to appear in 3 world cups for Nigeria. An autographed glove of Enyeama's would go to a lucky fan during the celebration as Nigeria celebrates one of the better goalkeepers it has had in its history. "Nothing matches being recognized by your own country. I am very excited at the prospect of reaching 100 caps, and more so at the decision by the NFF to honour me on the day," Enyeama told the federation's website.
Enyeama has stated that he intends to carry on keeping for the super eagles and win matches. Congratulations to Vincent Enyeama who becomes only the second player to reach 100 caps for Nigeria since the inception of the NFF(formerly NFA) 70 years ago.


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Friday, December 12, 2008
What time is it?
This clock is making a better wreath holder than timepiece - television filming was underway for the famed Christmas parade and Main Street looked completely different from its normal holiday look for a few days, including this new use for the clocks...
Labels: Magic Kingdom
3 comments:
- Gator Chris said...
I suspect this was done to help mask the fact that the parade is *not* aired live (minimize the visual intrusions).
- December 15, 2008 at 4:15 PM
- Michelle said...
Wow, that's brilliant! Wreaths, not just for decoration.
- December 17, 2008 at 8:19 AM
- Andy said...
Very interesting, I never even put that together but it makes prefect sense!
- December 23, 2008 at 8:26 AM
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Wax on. Wax off. I am the karate kid of singing. No, I'm not talking about the fancy karate-kick-with-a-broken-ankle kind of karate kid. I mean the washing-and-waxing- dilapidated-cars kind. Except instead of cars, I have five notes. Up and down. On a rolled R. Sometimes—if I'm really doing well—on an eee vowel. Absolutely, positively, no consonants. Except g. Sometimes there's a g consonant.
This has been a major part of my singing life for the last two months.
I recently started voice lessons again. My teacher is amazing. And very technical. And exacting.
And thus began my hour-long, "do-or-do-not-there-is-no-try" lessons and multiple hours of weekly practice on five notes. Up and down. Rolled r's. The occasional g.
It's not as boring as it sounds. The whole time I'm thinking about whether my larynx is open, whether my vocal folds are relaxed, whether the ligaments are stretched or loose, what my soft-palate is doing, how my hard palate is placed, keeping my tongue in the right place at the right time, and a whole host of other things. That's a lot to do in five little notes, up and down the scale.
Why? Why I am doing this? If you imagine the voice as a series of bicycle chains and gears, mine don't flow together as well as they could and the switch between them is sticky. Plus, one of the chains is hit or miss, performance wise. That was never a problem as long as I was on the flat, so to speak, but anything really challenging showed the weaknesses. The aim of these lessons is to work these chains and gears, or voice registers, so that they run smoothly and perfectly, no matter the conditions. And so that I can sing Strauss. And meaty Mozart arias. And all sorts of other music I've always shied away from.
I should be thrilled. And I am, but…
Here's the thing. Voices generally match bodies. What I mean is—from a physical standpoint—a tall woman with a large jaw has a much bigger instrument than a short, slight woman. All that means—really—is that the tall woman doesn't have to work as hard as the slight woman to produce a big sound.
But it does, on some level, go farther than that. We also expect that voices match bodies in a more specific sense (regardless of whether it's true). Tall, willowy blonde with ankles the circumference of pencils? Surely she has an ethereal, super-high voice that spins and spins and spins into the rafters before floating down and wafting around you.
Squashy, curvy woman with a big jaw and meaty wrists? Of course you're going to get a big sound that surges through the room, envelops you, slaps you around a bit, and then sinks into your bones.
I want to sound like the tall, willowy blonde with ankles the circumference of pencils. I don't want to sound like that squashy, curvy woman with meaty wrists.
Why? Because my whole life I have wished I had ankles that might snap at slightest misstep. (Not really. It's metaphorical.)
I have never looked like that. And I won't ever look like that, either. But in some ways, trying to emulate this light, floaty voice made me feel willowy, even if only for a few minutes.
I remember being a slim kid who was still taller, broader, and just plain bigger than every other kid around me. At the age of twelve, a distant uncle tried entice me to work on his farm for a few weeks because, you know, I was "sturdy".
I don't know a single woman who genuinely wants to be sturdy. Myself included.
Tapping into this big, meaty voice I supposedly have has required me to confront demons that seem to plague me no matter what I'm doing or what the situation is. Or how much weight I lose. It's not a fun process.
I imagine that's why it's called "personal growth".
While I continue to ponder that, I must get back to my five notes up and down.
We tried the octave last week, but my teacher quickly decided I wasn't ready for eight notes at time. Maybe next month, she said.
Wax on. Wax off. Do-re-mi-fa-sol. Sol-fa-mi-re-do.


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[13] Considering that the good results and popularity of a search engine is decided by its capacity to generate the most appropriate outcomes to any supplied search, very poor excellent or irrelevant search results could lead on consumers to search out other search sources. Search engines responded by establishing additional complicated position algorithms, taking into consideration supplemental variables which were harder for webmasters to control. In 2005, an annual convention, AIRWeb, Adversarial Data Retrieval on the internet was created to convey collectively practitioners and researchers worried about search engine optimization and connected topics.[fourteen]
Early versions of search algorithms relied on webmaster-supplied data like the keyword meta tag or index information in engines like ALIWEB. Meta tags give a guidebook to every website page's content material. Working with meta facts to index pages was located to generally be under reputable, nevertheless, as the webmaster's selection of keywords while in the meta tag could possibly be an inaccurate illustration of the location's real content. Inaccurate, incomplete, and inconsistent data in meta tags could and did lead to internet pages to rank for irrelevant searches.
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Good morning!!
I know this is not a good move if you've just started to blog, but today we're leaving for a very short trip to Europe. That means I decided to reschedule the Weekly RoundUp post for today.
I will tell you all about our tour next week.
Have an amazing week+weekend!! I know I will :)
An ode to colours and amazing images here and here (via VSL).
Where did France's wine go?
Believe me, you never fall this graciously.
Red Bull always does it better.
Nr. 23 is everything. Happy Birthday!
So me one and a half year ago. I wonder that the graph for "after marriage" would look like.
Important when travelling.
An insider's glimpse of the Tory Burch Fall 2013 show.
Attacking the birds on TV.
I haven't read the books and I won't watch the series. I refuse. I won't become a GoT freak.
A pinch more: tripping over subway stairs - this comment is absolutely right: "Fantastic how many people break into a little sprightly jog after they trip". I actually do the same.


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Citing alarming statistics regarding teen suicide, both county officials and a Pasadena nonprofit organization have set out to combat the problem.
The Los Angeles County Board of Supervisors approved a plan Tuesday to offer Internet-based suicide prevention training to school officials.
Meanwhile, a Pasadena-based nonprofit organization is trying to fill support groups with depressed and bipolar teenagers to help them cope with their illnesses.
The Board of Supervisors gave its approval to a $765,000 project to give officials in the county's 81 school district access to a Web-based suicide prevention training system over the next three years, according to county documents. The program will be paid for by state funds set aside for mental health.
The program was proposed by Los Angeles County Department of Public Health Director Marvin Southard.
In a letter to the board, Southard said the program had the potential to reach millions of students, their family members and school faculty.
"This coordinated expansion of suicide prevention measures will make a difference in alleviating the problems that have been statistically identified as ending overwhelmingly in chronically serious mental illness and even death," Southard said.
The Department of Public Health will contract with the Los Angeles County Office of Education's Center for Distance and Online Learning to have the Internet system set up and maintained, Southard said.
Officials will receive input from the Los Angeles Unified School District's Youth Suicide Prevention Program – the only school suicide prevention program in the United States, Southard said. LAUSD, which has operated the suicide prevention program since 1986, has about 800,000 students and one of the lowest suicide rates in the nation, he added.
But the work is not over once a depressed or potentially suicidal teenager is identified, said Marsha Gifford, executive director of the Mental Health Alliance for Teenagers in Pasadena.
Gifford's nonprofit organization, which opened its doors last April, offers an aspect of treatment for teens suffering from depression or bipolar disorder she said she believed is sorely lacking throughout the country: peer-support groups.
MHAT brings teenagers suffering from depression or bipolar disorder together with a licensed clinician to talk about their experiences with the diseases, Gifford said.
"It helps their self-esteem to be able to do that: talking to each other about the same problems that they're going through," Gifford said.
One class of about a half-dozen teenagers currently attends the group on a weekly basis, she said. Officials want to expand the program and are looking for teens who could benefit from the group.
By the end of the year, Gifford said she plans to add another two classes.
Participants are charged $20 per week to help offset the cost of the clinician, she said.
Gifford and Southard both used statistics to illustrate the need for action on the issue of teen suicide.
Every two hours, a teenager commits suicide in the United States, Gifford said, and teen suicides have tripled since 1970.
According to Southard and a report from the Centers for Disease Control and Prevention, suicide is the third leading cause of death for young people ages 15 to 24. In that age group, there are between 100 and 200 suicide attempts for every successful suicide, according to the CDC.
The CDC also reported that 14.5 percent of American high school students reported considering suicide in the previous 12 months, and 6.9 percent of them had made at least one attempt.
Gifford said there is no national organization that provides peer-support groups for depressed or bipolar teenagers. She said she hopes that one day MHAT will meet that need.
She said she became involved in the subject because both she and her son suffer from bipolar disorder.
"I tried to find a support group for him (my son)," Gifford said. "I couldn't find anything, so I wanted to start up something that would help other teens."
For more information on MHAT, call 626-794-2007.
626-962-8811, ext. 4586


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Cheers to the weekend! I hope everyone has something fun planned. The weather is supposed to be gorgeous (following the foot of snow we got on Tuesday- Colorado is weird), so I'm planning on spending as much time outside as possible. Maybe I'll be able to re-establish my disappearing beach tan. Maybe. In the meantime, enjoy these fun links from the week! xx
Mountains [Yosemite National Park hikes- dedicated to Danimal's vaca there tomorrow!].
Mode [Nanashuka Spring 2013].
How to pin like a pro.
Big cats like boxes too.
^^^And that made me think of one of my favs, Christian the lion.
The FCC supports the F-word.
I'm so obsessed with this wrap skirt. I want it, I want it, I want it!
The best dad ever.
I will definitely make family dinners mandatory one day.
The road to success is often
A Bill Murray story nobody will believe.
Remember that Dove Beauty Sketch from last week? Men's version. One point for the dudes.
I love this DIY for upgraded entertaining.
A Cinco de Mango menu. I like it.
Jimmy Kimmel interviews hipsters at Coachella. Hilarious.
I am in love with these sandals! And for only $42? Sold.
Image via everyday Occasions


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Donal- English, History, Writing, Reading, Studying, "Getting it done"
Donal- English, History, Writing, Reading, Studying, "Getting it done"
I'm CBEST certified, and I've worked privately with students as well as with after-school companies. Recently I helped put together an after-school supplemental program for a charter school's CAHSEE prep. As a result, we had a 90 percent passing rate in total for all classes participating, a record!
I believe in three things when it comes to learning: routine, preparation and repetition. After a couple lessons of getting to know each other, it's important to develop a consistent schedule...
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Want more info about DONAL T.? Get free advice from education experts and Noodle community members.


text:
The Secrets of the Dark is by debut Arka Chakrabarti who spins a tale so intricate that leaves you breathless. The book revolves around the mystical land of Gaya, two immenent prophecies bind the fate of men and empires alike. It is said that the Destroyer who will be born of royalty, in the Land of the Setting Sun will bring the empires down. For an instant you get a deja vu of Oedipus Rex and a lot of heckles are up.
"The secrets of the dark are sometimes so terrible that they are better left unsaid". The book takes you on a journey where you empathize with the protagonist. You feel his desperation, his unquenchable desire for vengeance. If an author is able to emotionally engage their readers to this level, I personally feel half his job is done! Arka's style of writing is probably an icing on the cake!
To be honest the fact that Arka belongs to Kolkata a lot of expectations are built for me. No biases here just a soft corner for my hometown, where Bengali's are known for their penchant for Literature and their writing skills are commendable. The fact that Arka impressed me and so much more is an understatement.
What one must consider is that Arka is under tremendous pressure, given the fact that with this book, he is in the same league as Amish Tripathi and Ashwin Sanghi who has done an exceptional job and have already raised the bar. To deliver something which is worth a read is in itself half a battle won for Arka. What totally hooked me is first the writing style and the second is just how engaging the book was.
Given the fact that I have a full time career at hand I found it hard to treat this book as a light read. The moment the mind wandered off, I had to go back to read those pages again to get the grip of the plot, the book was that engaging. I could barely wait to finish the book and wished, what was for the millionth time, that I could read this book in leisure when I can savor it as the story unfolded. Written in a lucid, free flowing way, the plot of comprehensible and concise that is why this book stands tall in the historical fiction category which has such great contenders.
Pick this book up because it has the ability to surprise you and debut authors need all the encouragement they can get.
My rating is a 3.75/5
Publisher : Srishti Publishers
Genre : Hictorical Fiction
Price : Rs195/-