text:
Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01249443
Recruitment Status : Terminated (Inadequate accrual rate)
First Posted : November 29, 2010
Last Update Posted : December 21, 2017
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
This phase I clinical trial is studying the side effects and the best dose of vorinostat when given together with paclitaxel and carboplatin in treating patients with metastatic or recurrent solid tumors and human immunodeficiency virus (HIV) infection. Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving vorinostat together with paclitaxel and carboplatin may kill more tumor cells.
NOTE: An administrative decision was made by NCI to halt further study of vorinostat in this specific patient population as of February 1, 2013. No patients remain on vorinostat. Going forward this study will determine the safety and tolerability of the paclitaxel and carboplatin combination in this patient population.
|Condition or disease
|HIV Infection Recurrent Anal Cancer Recurrent Breast Cancer Recurrent Esophageal Cancer Recurrent Gastric Cancer Recurrent Metastatic Squamous Neck Cancer With Occult Primary Recurrent Non-small Cell Lung Cancer Recurrent Ovarian Epithelial Cancer Recurrent Salivary Gland Cancer Recurrent Squamous Cell Carcinoma of the Hypopharynx Recurrent Squamous Cell Carcinoma of the Larynx Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity Recurrent Squamous Cell Carcinoma of the Nasopharynx Recurrent Squamous Cell Carcinoma of the Oropharynx Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity Recurrent Verrucous Carcinoma of the Larynx Recurrent Verrucous Carcinoma of the Oral Cavity Salivary Gland Squamous Cell Carcinoma Stage IV Anal Cancer Stage IV Breast Cancer Stage IV Esophageal Cancer Stage IV Gastric Cancer Stage IV Non-small Cell Lung Cancer Stage IV Ovarian Epithelial Cancer Stage IV Salivary Gland Cancer Stage IV Squamous Cell Carcinoma of the Hypopharynx Stage IV Squamous Cell Carcinoma of the Larynx Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity Stage IV Squamous Cell Carcinoma of the Nasopharynx Stage IV Squamous Cell Carcinoma of the Oropharynx Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity Stage IV Verrucous Carcinoma of the Larynx Stage IV Verrucous Carcinoma of the Oral Cavity Unspecified Adult Solid Tumor, Protocol Specific
|Drug: vorinostat Other: diagnostic laboratory biomarker analysis Other: pharmacological study Drug: carboplatin Drug: paclitaxel
|Phase 1
I. To determine the safety and tolerability of vorinostat in combination with paclitaxel and carboplatin in solid tumor patients with HIV infection.
II. To determine the maximal tolerated dose (MTD) of the combination in this patient population.
*NOTE: An administrative decision was made by Cancer Therapy Evaluation Program (CTEP) to halt further study of vorinostat in this specific patient population as of February 1, 2013, and no patients remain on vorinostat. The primary objective going forward will determine the safety and tolerability of the paclitaxel and carboplatin combination in this patient population.
I. To preliminarily assess response rates of the therapeutic combination in lung, head and neck, and esophageal cancers.
II. To evaluate the pathological characteristics of non-acquired immunodeficiency syndrome (AIDS) defining cancers of the upper aerodigestive tract.
III. To determine the presence and oncogenic activity of human papillomavirus (HPV) infection in tumor tissues and to correlate HPV infection with clinical outcomes.
IV. To investigate possible pharmacokinetic interactions between paclitaxel and antiretroviral therapy in persons with HIV infection.
OUTLINE: This is a multicenter, dose-escalation study of vorinostat followed by an expansion cohort study.
Patients receive vorinostat orally (PO) once daily on days 1-5 and paclitaxel intravenously (IV) over 3 hours and carboplatin IV over 30 minutes on day 3. Treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity.
Some patients undergo blood sample collection at baseline and periodically during course 1 for pharmacokinetic studies and HIV viral load analysis.
Note: An administrative decision was made by CTEP to halt further study of vorinostat in this specific patient population as of February 1, 2013. No patients remain on vorinostat. The primary objective going forward will determine the safety and tolerability of the paclitaxel and carboplatin combination in this patient population, without vorinostat. The information pertaining to vorinostat is for historical purposes.
After completion of study therapy, patients are followed up every 6 months for up to 3 years.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|17 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase 1 Study of Paclitaxel and Carboplatin in Solid Tumors (With Focus on Upper Aerodigestive Cancers) in Persons With HIV Infection
|Actual Study Start Date :
|November 2013
|Actual Primary Completion Date :
|May 2016
|Actual Study Completion Date :
|December 2017
Experimental: Treatment (carboplatin, paclitaxel)
Patients receive paclitaxel IV over 3 hours and carboplatin IV over 30 minutes on day 3. Treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity.
Before February 1, 2013, patients also received vorinostat PO once daily on days 1-5 with paclitaxel and carboplatin.
Drug: vorinostat
Given PO
Other Names:
Other: diagnostic laboratory biomarker analysis
Correlative studies
Other: pharmacological study
Correlative studies
Other Name: pharmacological studies
Drug: carboplatin
Given IV
Other Names:
Drug: paclitaxel
Given IV
Other Names:
- Incidence of adverse events during paclitaxel and carboplatin treatment according to dose-limiting toxicities (DLTs), graded using Common Terminology Criteria for Adverse Events version 4.0 (CTCAE v4.0) [ Time Frame: 21 days ]
- Response rates in patients with lung, head and neck, and esophageal cancers assessed by Response Evaluation Criteria for Solid Tumors (RECIST) 1.1 [ Time Frame: Up to 3 years ]For each stratum, binomial proportions and their 95% confidence intervals will be used to preliminarily assess response rates of the therapeutic combination in lung, head and neck, and esophageal cancers.
- Effects of therapy on HIV viral load and CD4 cell count [ Time Frame: Baseline and at 6, 12, and 18 weeks ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients must have known HIV infection and histologically confirmed solid malignancy that is metastatic or unresectable and is therefore incurable; although the focus of this trial will be on upper aerodigestive cancers (non-small cell lung cancer, head and neck squamous cell carcinoma, and non-gastroesophageal junction esophageal cancer), patients with other incurable solid tumor with disease potentially sensitive to carboplatin and/or taxanes (including but not limited to salivary gland cancer, gastric cancer, breast cancer, ovarian cancer, or anal cancer, BUT excluding Kaposi sarcoma), will be eligible
- Up to 1 prior systemic therapy regimen will be permitted for palliative treatment of metastatic or unresectable relapsed disease; however, previous chemotherapy delivered with curative-intent (i.e., chemoradiotherapy or adjuvant [postoperative] chemotherapy at a time disease was considered potentially curable) will be permitted; prior taxane (including paclitaxel or docetaxel) and/or platinum exposure will be permitted; however, patients must not experience disease progression within 3 months of platinum-based therapy; at least 4 weeks must have elapsed since prior chemotherapy or radiation therapy, 6 weeks if the last regimen included carmustine (BCNU) or mitomycin C; toxicities from prior anticancer therapy must have recovered to =< Grade 1
- Serologic documentation of HIV infection at any time prior to study entry, as evidenced by positive enzyme-linked immunosorbent assay (ELISA), positive Western Blot, or any other federally approved licensed HIV test; a positive HIV viral load prior to study entry will also be permitted
- Eastern Cooperative Oncology Group (ECOG) performance status =< 2 (Karnofsky >= 50%)
- Documented life expectancy of greater than 12 weeks
- Leukocytes >= 3,000/mcL
- Absolute neutrophil count >= 1,500/mcL
- Platelets >= 100,000/mcL
- Total bilirubin within normal institutional limits
- Aspartate aminotransferase (AST)(serum glutamic-oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT)(serum glutamic-pyruvic transaminase [SGPT]) =< 2.5 X institutional upper limit of normal
- Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal
- Additionally, serum magnesium and potassium must be within institutional normal limits, and a CD4 count > 100/mcL will be required within 2 weeks of study participation
- Presence of at least one measureable tumor lesion is required
- Participating patients must receive medically appropriate care and treatment for HIV infection, including antiretroviral medications, when clinically indicated, and should be under the care of a physician experienced in HIV management; with the exception of treatment with zidovudine and stavudine, patients will be eligible regardless of antiretroviral regimen (no antiretroviral therapy, nonnucleoside reverse transcriptase inhibitors [NNRTI]-based therapy, or protease inhibitor based therapy), provided there is no intention to initiate therapy or the regimen has been stable for at least 4 weeks with no intention to change the regimen within 8 weeks following study entry; the exact regimen used for HIV therapy will be captured on Case Report Forms; as study-specific (antiretroviral therapy-based) strata fill, however, only patients fitting the remaining open strata will be accrued
- Because histone deacetylase inhibitors as well as other therapeutic agents used in this trial are known to be teratogenic, women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, during the duration of study participation, and for at least 3 months following study completion; should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately; women of child-bearing potential must have a negative pregnancy test within 7 days before initiation of study drug dosing; post menopausal women must be amenorrheic for at least 12 months to be considered of non-childbearing potential; (Note: A woman of childbearing potential is one who is biologically capable of becoming pregnant; this includes women who are using contraceptives or whose sexual partners are either sterile or using contraceptives)
- Ability to understand and the willingness to sign a written informed consent document; as the correlative studies are critical to the clinical and scientific value of the trial, CD4 count/HIV viral load determinations will be required, and participation in the tumor-based correlative studies will be strongly recommended; additionally, investigators MUST request sample donation to the AIDS Cancer Specimen Resource (ACSR); however, the patient may refuse sample donation; patients accrued to the expansion phase of the study will be required to undergo pharmacokinetic sampling
- Subjects must in the opinion of the Investigator be capable of complying with this protocol
Exclusion Criteria:
- Patients who have had chemotherapy or radiotherapy within 4 weeks (6 weeks for nitrosoureas or mitomycin C) prior to entering the study or those who have not recovered from adverse events (toxicities not improved to =< Grade 1) due to agents administered more than 4 weeks earlier; additionally, patients experiencing disease progression within 3 months of platinum-based therapy will be excluded from trial participation
- Due to availability of effective first- and second-line therapies (as well as disease-specific clinical trials), patients with diagnosis of active Kaposi sarcoma will be excluded from study participation; however, persons with other active malignancy with prior history of Kaposi sarcoma can be considered for participation at the discretion of the Study Chair
- Patients may not be receiving any other investigational agents
- Patients with known brain metastases should be excluded from this clinical trial because of their poor prognosis and because they often develop progressive neurologic dysfunction that would confound the evaluation of neurologic and other adverse events
- History of allergic reactions attributed to compounds of similar chemical or biologic composition to the study agents used in study (including hypersensitivity to paclitaxel, Cremophor, or platins)
- For subjects assigned to take vorinostat, inability to take oral medications; vorinostat capsules must be administered whole; note: this criterion does NOT apply to subjects treated on the Expansion Cohort (accruals post February 1, 2013)
- As ketoconazole may inhibit paclitaxel metabolism, patients receiving ketoconazole for any treatment indication are ineligible; patients receiving any other medications or substances that are inhibitors or inducers of CYP450 enzymes will be eligible; however, use all such medications or substances must be documented in the Case Report Forms
- For subjects assigned to take vorinostat, prior exposure to vorinostat or other known histone deacetylase (HDAC) inhibitors for cancer therapy; patients should not have taken valproic acid, another histone deacetylase inhibitor, for at least 2 weeks prior to study enrollment; note: this criterion does NOT apply to subjects treated on the Expansion Cohort (accruals post February 1, 2013)
- Since zidovudine and stavudine have potential for severe hematological toxicity potentially overlapping with toxicities of the study therapy, treatment with these agents will be disallowed
- Due to potential toxicity associated with study therapy (particularly with paclitaxel), patients with peripheral neuropathy > Grade 1 will be excluded from study participation
- Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, opportunistic infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements; patients with HIV infection will be eligible provided they meet the criteria specified; patients with known Hepatitis B infection should be screened for active disease prior to study participation; patients with chronic Hepatitis C infection will be eligible at the discretion of the treating investigator
- Pregnant women are excluded from this study and women who become pregnant while on study must be immediately discontinued; women who are breastfeeding will not be eligible for study participation
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01249443
|United States, California
|UC San Diego Moores Cancer Center
|La Jolla, California, United States, 92093
|UCLA Center for Clinical AIDS Research and Education
|Los Angeles, California, United States, 90035
|United States, District of Columbia
|Lombardi Comprehensive Cancer Center at Georgetown University
|Washington, District of Columbia, United States, 20057
|United States, Florida
|University of Miami Miller School of Medicine-Sylvester Cancer Center
|Miami, Florida, United States, 33136
|United States, Illinois
|John H. Stroger Jr. Hospital of Cook County
|Chicago, Illinois, United States, 60612
|United States, Massachusetts
|Boston Medical Center
|Boston, Massachusetts, United States, 02118
|United States, Missouri
|Siteman Cancer Center at Washington University
|Saint Louis, Missouri, United States, 63110
|United States, New York
|Montefiore Medical Center
|Bronx, New York, United States, 10467-2490
|United States, Pennsylvania
|Pennsylvania Oncology Hematology Associates
|Philadelphia, Pennsylvania, United States, 19106
|United States, Washington
|Benaroya Research Institute at Virginia Mason
|Seattle, Washington, United States, 98101-2795
|Principal Investigator:
|Missak Haigentz
|AIDS Associated Malignancies Clinical Trials Consortium
|Responsible Party:
|AIDS Malignancy Consortium
|ClinicalTrials.gov Identifier:
|NCT01249443 History of Changes
|Other Study ID Numbers:
NCI-2011-02511 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
CDR0000689900 ( Registry Identifier: clinicaltrials.gov )
AMC-078 ( Other Identifier: AIDS - Associated Malignancies Clinical Trials Consortium )
AMC-078 ( Other Identifier: CTEP )
U01CA121947 ( U.S. NIH Grant/Contract )
|First Posted:
|November 29, 2010 Key Record Dates
|Last Update Posted:
|December 21, 2017
|Last Verified:
|December 2017
|Studies a U.S. FDA-regulated Drug Product:
|Studies a U.S. FDA-regulated Device Product:
|Product Manufactured in and Exported from the U.S.:
Additional relevant MeSH terms:
Breast Neoplasms
Communicable Diseases
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
HIV Infections
Acquired Immunodeficiency Syndrome
Stomach Neoplasms
Esophageal Neoplasms
Laryngeal Diseases
Neoplasms, Glandular and Epithelial
Ovarian Neoplasms
Laryngeal Neoplasms
Oropharyngeal Neoplasms
Carcinoma, Verrucous
Salivary Gland Neoplasms
Nasopharyngeal Neoplasms
Paranasal Sinus Neoplasms
Anus Neoplasms
Head and Neck Neoplasms
Neoplasms, Unknown Primary
Neoplasms by Histologic Type
Neoplasms by Site
Breast Diseases
Skin Diseases
Respiratory Tract Neoplasms
Thoracic Neoplasms


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This biography was auto-generated by a GEDCOM import. It's a rough draft and needs to be edited.
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Our men's basic t-shirts can be worn alone or in combination with practically any other piece of clothing in the G-Star RAW collection. You'll find high-quality comfortable shirts made of 100% cotton to match every style in the book. Choose a fitted style or try a more loose fit. All men's basic t-shirts are made of the finest materials and are designed to make you look your best. Order a 2-pack and make sure you'll never go a day without our basic t-shirts again. If you're looking for printed tees make sure you check out our section of men's printed t-shirts too. Select to find your favourite basic t-shirts Using the left-hand menu you can easily select your favourite type of basic t-shirt. Start by selecting the colour and size you're looking for and indicate whether you want your t-shirt to have long sleeves short sleeves or no sleeves at all. By selecting the type of neckline you want your t-shirt to have you've created your personal collection of men's basic t-shirts. Now all you have to do is pick your favourite. Ordering men's basic t-shirts online With the G-Star RAW online store shopping for basic t-shirts just became a lot easier. To place an order simply click 'Add to bag' pay in our secured environment and have your t-shirt shipped to your home.
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PVC pipes have different ratings. Schedule 40 PVC pipes and fittings will have different applications than Schedule 80 PVC pipes. Schedule 80 pipes and fittings are thicker and stronger, and should be used to jobs that require higher system pressure and higher water temperature. The Drip Store uses schedule 40 PVC fittings up to 1" that are suitable for use in irrigation for landscape and agriculture. All sizes of the PVC Schedule 40 pipes and fittings are manufactured in strict accordance to the requirements of ASTM D1785 for physical dimensions and tolerances.
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Whether you are installing a new irrigation system or only making a repair, knowing how to install the PVC fittings and pipe can be a useful skill that can make your irrigation system last. Please read below our recommendations for a good installation or repair.
Tools and materials suggested:
Before you begin the process of installing a new irrigation system or start a repair, please be aware of the correct steps needed, and that inspection is needed on completion.
After inspecting the system and finding the cause of the problem, you will be in the position to know the equipment needed for the repair. If you are unable to obtain the PVC fittings in the correct size, you may need to use some combination of fittings to satisfy your need.
Once you have all the required measurements, cut the PVC pipe in accordance with your notes. Stretch the tape measure along the pipe to the required length and mark the distance to be cut with a pencil line. Secure the fittings to prevent them from slipping while they are being cut. Ensure that your efforts were correct by drying the fitting and pipe and then testing that they slot into place as they should and are properly aligned. When the fittings are firmly in place and secure, trace a pencil line along the edge of the fittings so that you can return them to the correct position when you glue them. Once this is complete, you can disassemble the pipe and fittings.
Make sure that the fittings and pipe are clean. Open the Red and Blue PVC glue and using the brush swab the glue around the outside edges of the pipes and inside the side of the fitting you are gluing. Make sure to limit this action to the portions that will be fitted together, Insert the pipe into the fitting and allow it to dry for a few seconds. When all the parts are correctly in place, quickly use a rag to wipe away any excess glue that remains on the outside of the pipes before it dries. After completing the job refrain from turning on the system for a few hours. After few hours pass, you may cover some of the pipe but leave all the connections exposed. Turn the system on and review to make sure that no leaks are found. At this point you can cover the rest of the pipe.
This information is from doityourself.com, a place where you can find useful information on home repair.
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We have all been there... You open your fridge. You grab a bottle of soy sauce and do the sniff test. You flip over the bottle looking for the expiration date and think about the soy sauce's shelf life. You try to remember how long ago did you buy it and when you last used it.
AsianSupper investigates what the shelf life for Asian condiments are after they are opened. What we found out? It varies, depending on the type of sauce and even the specific brand. Properly stored, all sauces should have a shelf life of at least one to three months. On the Kikkoman website, their recommendation is "For the best quality, we recommend using the sauces within one month of opening." Hmm... this seemed to contradict all my cooking memories growing up. And so, I did what any good Asian daughter would do. I asked the Asian Supper moms (Umma and Nang).
Below are Asian Supper's table of condiments to 5 popular Asian sauces:
Oyster sauce = 6 months max, once it is opened in the refrigerator.
Soy sauce = until you finish using it. In Asian countries, older soy sauce is revered.
Fish sauce = depending how salty it is, but it's been boiled down to very long time, and it should last for a long time in the refrigerator - 1 yr or longer, I can say.
Hoisin sauce = It has starch, and different seasoning and vinegar - about 5-6 months when opened
Gochujang (Korean Hot Pepper Sauce) = Usually it lasts for a long time - longer in the refrigeration, I suppose. In Korea, they usually kept it in a big hangari (ceramic jar) outside, and kept it forever - usually gochujang and doenjang, they say the longer you kept the better it taste...
Some tips on keeping your Asian sauces fresh:
• Make sure the opening of the bottle is clean at all times
• Always keep the container tightly sealed
• Store non-refrigerated sauces in the refrigerator to keep the flavor at its peak longer (even if refrigeration is not required)
• Buy smaller bottles (especially if you are new to Asian cooking at home). Asian Supper recommends buying the smallest bottle possible for your recipes. Not only does it save space, it ensures that your Asian condiments and sauces have the highest peak of flavor.
Want us to investigate what the condiment shelf life is for other Asian sauces or ingredients? Tell us in the comments section and we'll compile an updated list!


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Trashed on Amazon
I'm in Manchester, England now. I'll be speaking here on Friday evening and running an all-day zazen on Saturday. You can find the relevant likes by clicking here.
Gudo Nishijima's translation and commentary on Nagarjuna's Fundamental Wisdom of the Middle Way is finally out and available now at decent bookshops all over the USA as well as on the Barnes & Noble and Amazon websites. I helped Nishijima fix up his English and contributed extensively to the commentary so I received a co-writer credit.
But speaking of Amazon, the book has been getting a total trashing in their reader reviews section. It's been so nasty and vindictive in there that I thought it would be good to address the matter.
There are now five extraordinarily mean-spirited and angry one star reviews of the book on Amazon. You can read them for yourself if you enjoy bile and vitrol. But I'll try to summarize the key issues here without quite so much bitterness.
The main criticisms appear to be that 1) some believe the book is presented in such a way as to deliberately fool people who want to buy Jay Garfield's translation of the same Nagarjuna poem into thinking this is his, and that 2) the book is not an accurate translation of the poem itself.
The first criticism is based on the fact that both Garfield and Nishijima chose to title their books Fundamental Wisdom of the Middle Way. This is one of the standard English translations of the Sanskrit title of the work, Mulamadhyamakakarika. While some scholarly translations such as the one by Kenneth Inada used the Sanskrit, Monkfish Books thought that would be too difficult for most readers and instead chose to go with a standard English translation. Other translations of the Sanskrit title include Root Stanzas of the Middle Way, Fundamental Verses of the Middle Way and Fundamental Song of the Middle Way. Personally I did not notice that the title was the same as Garfield's and that his was the only currently available English version that used this specific translation. Had I noticed this, I probably would have substituted something like "poem" for the word "wisdom" in the title. I regret having not done so, but it's too late to change it now.
Also some have said that the cover resembles the cover of the Garfield version. It's true. It does. It also resembles the covers of about 80% of all books on Buddhism these days. Monkfish followed the very standard practice of illustrating the cover with an ancient Chinese painting of the master who wrote the original piece. Pretty much every publisher follows this practice when designing a cover for a translation of an ancient Buddhist work.
In any case none of this was an attempt to deceive the public into thinking they were buying Garfield's translation. Why would anyone want to do that? It's not as if the Garfield translation sells in Harry Potter-like or Twilight-like quantities, thus making it attractive to try and copy. It's also not as if the intended readership are the kinds of people who'd buy the book without checking out who wrote it first. It's an absurd allegation, but one that is repeated in four of the five negative reviews on Amazon.
Some of the other allegations are similarly absurd. One reviewer states that, "Dogen, Godzilla, and Nishijima--the autonomic nervous system-- are all more fully present than Nagarjuna." Godzilla is mentioned once in my introductory essay in a sentence in which I apologize to readers familiar with my other books for not mentioning Godzilla in this one. There is one commentary in which Nishijima outlines his ideas about the autonomic nervous system. I quoted this commentary in full in an earlier posting on this blog, which can be found by clicking here and scrolling about halfway down the piece. This commentary is then referenced briefly several more times in later commentaries. Dogen is mentioned a lot. But Nishijima says right in his introduction, "My own thoughts regarding Buddhism rely solely upon what Master Dogen wrote about the philosophy. So when reading the Mulamadhyamakakarika it is impossible for me not to be influenced by Master Dogen's Buddhist ideas." Why then would it be surprising to find a lot of references to Dogen in the commentaries?
As for the book not being an accurate translation, this is a more complex issue. I address it in great detail in both my foreword and my afterword to the book. I have put those on a webpage so you can read them in full. Just click here.
In part I said there that, "We'll never know Nagarjuna's real intentions. We'll only ever know what his words mean to us. This book represents what those words mean to Gudo Nishijima." Further along I wrote, "Every translation of anything is an interpretation. For fifteen years I worked at a job where one of my main tasks was translating the dialogue of cheap Japanese monster movies into English. Even when doing this seemingly simple and straightforward work I had to change a lot of details to make them comprehensible to English speaking people. Nagarjuna's Mulamadhyamakakarika is a lot more complex than any monster movie. For one thing it is a poem. A poem isn't like an instruction manual in which there is only one correct way to interpret its meaning. There are as many ways to understand a poem as there are people to read it and all of them are valid in their own right."
I also said in the afterword, "I still don't know whether it will be accepted as a translation of Nagarjuna or not. I'm anticipating that a lot of scholarly types will debate its merits as a translation without ever giving the philosophical points contained within it much notice. If they do so, that would be a shame." This seems to be precisely what is happening. The current critics on Amazon don't really comment on the actual contents of the book. One even admits that he hasn't read it! Is it fair to criticize a book you have not even bothered to read?
Kumarajiva was a fifth century Indian scholar who translated many of the canonical works of Buddhism into Chinese. His translation of the Heart Sutra is still chanted in Buddhist monasteries all over the world. Nishijima contends that when it came to Mulamadhyamikakarika, Kumarajiva got it wrong. He simply did not understand what Nagarjuna was talking about. Furthermore, Nishijima contends that all later translations and commentaries have relied upon Kumarajiva's faulty understanding of the poem — even the very ancient ones. As evidence of this, Nishijima notes that Dogen quotes extensively from Nagarjuna's other works but never mentions Mulamadhyamikakarika, which is regarded as Nagarjuna's masterwork. This, he says, is because Dogen had access only to Kumarajiva's translation and found it lacking. Therefore Nishijima deliberately avoided consulting any other translations of the work either in English or in Japanese. It's no wonder then that his translation does not sound much like any of the others.
I said it before and I'll say it again, this is a damned good book. If you are interested in knowing what I learned in fifteen years of studying Buddhism under Gudo Nishijima, most of it is in this book. It is deep and difficult Buddhist philosophy. Nishijima Roshi believes that all of these ideas are present in Nagarjuna's poem. I trust that he found them there. But whether they are really there or not, I know that it's valuable stuff. If he found all of this philosophy in the wood grain of the wall he sat in front of every day for seventy years it would still be valuable stuff. Maybe he did but he thought it would be more believable to say he found it in Nagarjuna! (That's a joke, he was very methodical in his translation and he presents his translation methods to readers of the book very clearly. This is something few others have done.)
Some of you have written to me saying you've ordered the book or that you bought it in a store (hooray for you for supporting bookstores!). If you have read the book and you like it, please take a moment to go to Amazon and express your feelings. It would really help out a lot.


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Chances are you came across this site because you are interested in finding out more information on Emergency Medical Technician Career - EMT Courses, EMT Certifications and EMT training in Carlisle. EMT is an exciting and very rewarding career for those who love to help others in need. Our goal is to provide vital information you'll need to pursue this rewarding career as an EMT and also providing insights as to future advancements in this field as a Paramedic in Carlisle.
Did you also know that EMTs/Paramedics are a fast growing profession in the healthcare service provider industry? According to the US Bureau of Labor Statistics, employment of EMTs and Paramedics are predicted to grow rapidly at 33% between 2010 and 2020. The fact is, these types of employment opportunities can't be replaced or shipped overseas so there will always be an expanding demand for EMT and Paramedics all across the United States.
Distinctions between EMR, EMT and Paramedic in Carlisle, LA
In Carlisle, EMTs or Emergency Medical Technicians are professionals that establish a vital role in the health care process. They are usually the first to arrive at the patient's location and perform first aid. Most of the time, patient's lives depend on the EMTs since they are the ones that provide the initial care before the patients are rushed to the hospital for advanced medical treatments.
The main difference between an EMT and Paramedic is typically the level of certifications. Both EMT and Paramedic are Emergency Medical Technicians. Paramedics are an advanced EMT, also referred to as EMT-Paramedic. In the field of emergency medical service technicians, EMT Paramedic is the highest certification one can obtain.
First responders are often a crucial part in the calls they will receive and then have to quickly evaluate situations. First responders can be trained to use defibrillators, provide CPR, help out with emergency childbirth and also apply bandages and splints. Their basic responsibilities are to stabilize the situation and get the patient capable for transfer.
First Responder training in Carlisle Louisiana, is typically 46 hrs and CPR training is usually needed prior to taking a course. First Responders can anticipate an examination which range somewhere between 80-110 questions in addition to an assessment of field work.
An accelerate EMT Basic course in Carlisle, LA. will take around 120-160 hours of classroom instructions. Training requirements might differ slightly from state to state nevertheless; they are expected to carry out the NREMT examination between 70-100 questions, and a Psychomotor examination to obtain EMT Basic certification.
Similar to the other levels, EMT Advanced in Carlisle includes an itemized test of 150 questions and a more intense Psychomotor Assessment. Anytime students start training for EMT Advanced is when they will really begin to deeply study anatomy and physiology. EMT Advanced certification in Carlisle is often 250 hours in length.
Paramedic Exams in Carlisle are 80-120 questions and also includes a Psychomotor test plus the schooling can be up to 1,500 hrs. As you can see, the number of training hours jump drastically from EMT Advanced 250hrs to Paramedic 1,500hrs. This final milestone distinguishes Paramedics from other EMTs and it's the most prestigious achievement one can obtain in this rewarding career as an Emergency Medical Technician. Request Info to get started!


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The economy and the climate for Jeffco businesses were discussed by 11 political hopefuls from across the county last Friday morning at a candidates forum sponsored by the Jefferson County Economic Development Corp.
The forum, at the Holiday Inn at Wadsworth Boulevard and U.S. 285, was attended by about 50 people.
As might be expected, the discussion focused largely on what the candidates have accomplished in the business world and how much they are committed to improving conditions in the business sector.
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Divison Series reflection of competitive season
A telling scene played out around a small television set at a barbecue restaurant in Berkeley, Calif., this week during the final few innings of Giants-Reds Game 5. More >
Mozeliak watches proudly as Cards' pieces produce
Last winter, Cardinals general manager John Mozeliak was given the unenviable task of constructing a club capable of an encore. He'd have to do it, too, without a legendary manager and without the greatest hitter of the generation. More >
After thrilling Division Series, more surprises await
Whatever happens in the days and weeks ahead, this much is known: The 2012 Division Series have set up the road to the World Series like never before. More >
'Pen runs out of ink at critical juncture
Closers dream of the situation that Drew Storen faced in the ninth inning on Friday, his Nationals leading by two runs in the ninth inning. But after Storen followed Carlos Beltran's leadoff double with two quick outs, the game began unraveling. More >
Cardinals have perfected the art of the comeback
The Cardinals became the first team in Major League postseason history to come back from a six-run deficit and win a sudden-death game. No team had come back from more than a four-run deficit in a do-or-die contest. More >
Veteran DeRosa not sure of baseball future
For the most part, the group of Nationals players left speechless by their heartbreaking Game 5 loss will be back next year. More >
Wizard of Koz: Late magic lifts Cards to NLCS
The Cardinals stunned the Nationals with a four-run ninth inning to cap a comeback that was as improbable as the one this team had in an elimination game against the Rangers last October. More >
Yanks have little time for celebration as Tigers loom
The Yankees didn't have time to savor their win over the Orioles in Friday's Game 5 of the ALDS. They were scheduled to face the Tigers the next night in the first game of the ALCS. More >
Solid young core will help Nats bounce back
The Washington Nationals had a season to remember. It, however, came to an end they would have to work to forget. And it won't be easy, but the Nationals have a strong young core to work with. More >
Latest Cards comeback most remarkable of all
The Cardinals' Game 5 win over the Nationals, in some ways, was the most amazing of all of the Cards' comebacks -- even more remarkable than Game 6 of the 2011 World Series against Texas. More >
Did you know? NLDS Game 5: Cards 9, Nats 7
A look at some notable facts and figures from the St. Louis Cardinals' 9-7 victory over the Washington Nationals in Game 5 of the National League Division Series at Nationals Park on Friday night. More >
Rookies Kelly, Rosenthal step up in relief for Cards
Trevor Rosenthal and fellow rookie reliever Joe Kelly played an integral role in St. Louis' momentous comeback win in Washington on Friday. More >
Euphoric after rally, Cardinals believed all along
The Cardinals went from grasping at a comeback to grasping each others' jerseys in euphoria after they completed the largest comeback in any winner-take-all postseason game. More >
After falling flat early, Wainwright lifted by 'mates
This was what Adam Wainwright lives for -- starting in an elimination game -- until it wasn't, when he was shelled early. But Wainwright went from the lowest of lows to the highest of highs on Friday. More >
Cards get toughest at-bats from unlikely sources
Daniel Descalso and Pete Kozma, take your star turn. Instead of the Cardinals' big boppers getting the key hits in the Redbirds' comeback win Friday, it was the two light-hitting middle infielders. More >
Angelos: Orioles in position for sustained success
Orioles chairman and CEO Peter Angelos made his second appearance in five days following the organization's postseason run -- which ended with Friday's 3-1 Game 5 loss -- and spoke of building on a phenomenally successful 2012. More >
Orioles say 'see ya later' instead of 'goodbye'
The dramatic improvement of the Baltimore Orioles can be expressed in many ways. But one of the most telling ways is the respect that they now receive from the opposition. More >
Lynn to start NLCS opener should Cards advance
The Cardinals will not use Lance Lynn out of the bullpen on Friday in order to preserve him for a start in Game 1 of the National League Championship Series, should they advance. More >
Garcia likely to have exploratory surgery
Though Jaime Garcia plans to seek out a third opinion on his ailing left shoulder, the Cardinals are expecting the left-hander to undergo exploratory shoulder surgery by the end of the month. More >
Game 4 victory reminded Davey of Nats' early wins
Had the result been different, Nationals manager Davey Johnson surely wouldn't have been viewing his club's inability to put a runner past first base on Thursday as merely a flashback to earlier in the year. More >


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The Look
明けましてお目出度う y'all! That's "happy new year" for those who can't read Japanese.
Here's an email I got recently.
Attached is a picture of Behring Breivik, the guy who shot, bombed and killed about 77 people in Norway this summer. He has been examined by psychiatrists and they have come to the conclusion that he is/was a paranoid schizophrenic, meaning he was insane at the time of his murderous actions.
But look at his picture closely, look at his eyes...he is very balanced according to the Tibetan theory of "eye science."
I sometimes ask myself if this means that Hitler, Stalin, Osama and all other crazy wackos are also just paranoid schizos then?
So are these people really just sick or are they just simply "evil" ? This guy Behring Breivik planned and planned and worked at this for years and went to such lengths to kill these people that it is very hard for me to consider him sick, as most healthy and very intelligent people would not have managed the task of producing, orchestrating and manifesting such a killing even if they wanted to. Should that not say something about his sanity?
I think this is a really important question. And to me the question is, What is sanity and how does it relate to Enlightenment?
I think it's clear that there is no real correlation between I.Q. and morality. Some of the most immoral people in history have been extremely intelligent as measured by the accepted standards of measuring such things. Several of the people who followed Shoko Asahara's orders and placed poison gas on the Tokyo subway system were highly educated. Many of the top leaders of the Nazi party were also very brainy.
This means that the ability to carefully plan out and execute some specific operation does not relate at all with being a moral person. It is quite possible to create a very complex proceedure and to carry it out without having any sense of morality. Whatever you think really happened in Lower Manhattan on the morning of September 11, 2001, it was clear proof that planning and executing complex schemes does not require any sense of morality. Whoever did that stuff was very smart. I'm sure they all knew how to conduct themselves socially and be accepted as sane. If not, they wouldn't have been able to interact with the many people they needed to deal with in order to accomplish their goal. These were not raving lunatics. They never are...
But one would expect that enlightenment in the Buddhist sense would correlate with morality and just basic human decency. This is where things get tricky. Because it all depends on how one defines enlightenment.
The general consensus seems to be that an enlightened person is one who has undergone what they call an "enlightenment experience." This experience reveals to the enlightened person the true nature of reality. After having had this experience, the person is transformed into something more than what he or she was before.
But I suspect there is precious little more correlation between true morality and the ability to have one of these so-called "enlightenment experiences" than there is between true morality and the ability to score high on an I.Q. test.
OK. I'll back off a little there. At some level an "enlightenment experience" shows the person who has it the real meaning of moral action — that anything one does to another person is something one does to oneself. And I don't mean this in any kind of figurative or metaphorical sense. I mean that when Moe hits Curly on the head with a sledgehammer, Moe is really only hitting Moe on the head with a sledgehammer. It only appears to be Curly getting hit.
But that's not always what gets labeled as an "enlightenment experience." Often what passes for an "enlightenment experience" is something quite different. Sometimes it's much more like a drug-induced hallucination. People on psychedelic drugs often report feeling at one with the universe. But it's not the same kind of oneness. It's a oneness in which the experiencer owns that oneness and incorporates it into his/her sense of self, thereby making that sense of self infinitely big and infinitely exclusive.
Even if an "enlightenment experience" is genuine, the ego is very powerful and exceedingly clever. Absolutely anything, even a true experience of oneness with all things, can be transformed into something the ego can use to bolster itself.
As for the ability to achieve the stereotypical "look" that a realized master is supposed to have, this is even less correlated with morality or even with enlightenment. A decent actor can convincingly act out a variety or roles even when the actor has not experienced anything like what the character he's portraying is supposed to have experienced. It's easy to look the part of the balanced guru without being the least bit balanced.
Osama bin Laden could do it.
Shoko Asahara can do it.
Kirtanananda Swami Bhaktipada, who allegedly ordered several killings on the New Vrindaban Hare Krishna farm community could do it.
I suspect that Mike Myers can do it but refrained from doing it lest he look too much like his buddy...
...Deepak Chopra who has really got it down!
Which isn't to say Deepak is anything like Osama bin Laden, Shoko Asahara and Kirtananda. I don't think he is at all. But that beatific grin he's mastered doesn't prove it.
So sanity is something quite difficult to define. Like the famous quote about pornography, "you know it when you see it." But you don't know it just because someone looks the way the media tells you they're supposed to. It's much more subtle.
And people are uncomfortable with that. They want easy definitions that never change. Unfortunately, in real life easy definitions that never change are hard to come by. They want stereotypes that are reliable. But stereotypes are never reliable.


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1960's Retro Candy
Items 1-15 of 55
Items 1-15 of 55
What's groovy enough to go with bell-bottom jeans and mini skirts? Fruit Stripe Gum, Now and Laters, and Lemonheads, of course. Our nostalgic retro candy from the 1960's is full of the spirit of the decade of peace and love, as you can plainly see from the psychedelic color selection of Zotz.
Looking for an old-fashioned candy favorite that is fashionable, matches any outfit, and delightful to eat? Then you need a candy watch, and we sell them in bulk so you can have a new one daily, all year long. If anybody asks, tell them it's a 60's thing.
Our other retro candy selections from the 1960's include perennial must-haves, such as Starburst Fruit Chews, Swedish Fish, and Twizzlers. Did you know that SweeTarts were developed to be a less-messy version of Pixy Stix? Because we have both of these old-fashioned candy favorites, that means you have a choice when you shop with us: messy or less-messy.
Enjoy the selection of 1960's candy, and if you haven't already, browse our other decades, as well.


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In this activity, students quantitatively evaluate the accuracy of a classification and understand a simple difference/error matrix. Students sort birds into three possible classes based on each bird's beak: carnivores (meat eaters), herbivores... (View More) (plant eaters), and omnivores (meat and plant eaters). Students compare their answers with a given set of validation data and generate a difference/error matrix. Students discuss how to improve their accuracy based on identifying specific mistakes they made as indicated by the difference/error matrix. The resource includes color diagrams of common birds, a data table, and four student activity sheets. The activity is part of the Land Cover/Biology chapter of the GLOBE Teacher's Guide, and is supported by Land Cover/Biology protocols. GLOBE (Global Learning and Observation to Benefit the Environment) is a worldwide, hands-on, K-12 school-based science education program. (View Less)
Materials Cost: $5 - $10 per group of students


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Bubbling upAl Kominski moving his pizza shop, craft beer operations
Less than five years ago, Central Pennsylvania was somewhat of a craft-beer desert when it came to specialty brands by the bottle or draft.
But tucked away off Wertzville Road in Hampden Township was a little oasis known as Al's of Hampden, a small pizza shop that would help drive the mix-a-six trend and give local beer enthusiasts another option to sample those one-of-kind microbrews.
"We started with six taps and then grew to 14 and then 24," said Al Kominski, a Hazleton native who founded what he calls a "hole-in-the-wall" pizza shop in 2002.
Kominski jumped into the craft beer craze with both feet in 2008 as a way to grow his business.
In addition to the beer taps, which are constantly cycling through various beer labels, Al's has become a buffet of bottled options — both warm and cold — for customers. The pizza shop sells about 350 varieties of beer, and Kominski is always on the lookout for more.
"I get requests all the time," Kominski said.
That's part of the problem. For starters, the Valley Road restaurant's tight quarters make it tough to find room for any more beer.
And with growing competition from other restaurants in the area, cases and kegs of those nontraditional beers are harder to come by, Kominski said.
The latter led to the creation of Pizza Boy Brewing in 2011, an in-house label Kominski started for his own line of beer.
"I didn't want to be (solely) reliant on beer distributors," he said.
With certain brands, he was only able to get a case or two, which doesn't meet high customer demands in a growing area.
The Pizza Boy line of beer, which is made in the lower-level storage area of the building, has allowed Kominski to offer 28 beers at any time. His German-built beer system can brew up to 150-gallon batches, he said.
Pizza Boy currently makes 10 different styles of beer.
Business evolution
Before launching Pizza Boy, Al's was already in need of an expansion, said Kominski, 34, who began making pizzas when he was 13.
"We got even smaller," he said.
Everything Pizza Boy brews up for sale goes right back out the door.
"We brew on a cycle, but we can't keep up with what we sell," he said.
Hoping to take the business to new heights, Kominski purchased a 1.5-acre lot in the nearby Pyramid Business Park, where construction has begun on a 9,600-square-foot brewpub.
The new multimillion-dollar location, which expects to be done in April, will provide five times the seating for the restaurant side of the business and more than quadruple the number of beer taps.
His beer production also will ramp up to 600-gallon batches with the purchase of new equipment, and bottle varieties sold should double, he said.
The current restaurant is across the intersection, opposite the Cumberland Technology Park. It is surrounded by the construction of stores being built by Weis Markets and Giant Food Stores.
"In three years, this building would be obsolete," Kominski said of his current building, which he anticipates will be further pinched off to traffic by the new shopping centers. "We had to look forward. The area's growing, and we're growing."
With the new brewpub, Kominski said, he has plans to distribute kegs of his beer outside Central Pennsylvania and potentially into other states.
He expects the business, which employs about 26 people, to expand by another 20.
The new Al's will include outdoor dining space, which will be twice the size of the current restaurant, Kominski said. It will feature a separate kitchen and bar area with a wood-fired pizza oven.
Kominski said he is hoping to hire a five-star chef for the outdoor area.
The indoor area will carry on the traditional Al's menu with some new items, including steaks and rotisserie chicken, he said, plus a beer sampling area.
The Millennium Way site will utilize beer-serving tanks for Pizza Boy's core house beers that are on tap, which will create more efficiency in the brewing operations.
"It's going to be a big step for us," Kominski said. "It will be a bigger hole-in-the-wall pizza shop."
If the concept works, he said, he could see the potential in hiring a restaurant management group to open additional Al's of Hampden brewpubs in other areas.
"Everything we do is a risk," he said. "This should have been done five years ago, before we sold beer."
Market difference
Unlike Appalachian Brewing Co. in Harrisburg, Tröegs Brewing Co. in Derry Township and other regional craft brewers, Al's of Hampden has specialized in selling single bottles and six-packs of microbrews that have traditionally been available only at distributors in cases or kegs.
Al's also has a rotating list of craft beers on tap, including selections from Tröegs, for dine-in and carryout customers.
The Hampden Township pizza shop has built its local reputation on carrying one-of-a-kind beer labels.
With the launch of its Pizza Boy Brewing line, Al's has entered the brewpub market minus the distribution. To date, all of Al Kominski's beer styles have been sold in-house and in draft form only.
With the move to its new location next year, Al's will place even greater emphasis on its house beers for restaurant patrons and others stopping in to fill up their beer mugs, often known as growlers. Kominski also will begin selling kegs of Pizza Boy.
Kominski said he does have plans to begin distributing outside Central Pennsylvania — likely starting with the Pittsburgh and Philadelphia markets — once everything at the new restaurant is running smoothly. That could take a year, he said.
Craft beer growth
Growth of the craft-brewing industry in 2011 was 13 percent by volume compared to 2010, when growth was 12 percent, according to the Colorado-based Brewers Association, an organization of craft brewers.
Craft-brewing sales accounted for 5.7 percent of beer volume in 2011, the association said.
A craft beer is defined by Merriam-Webster as a specialty beer produced in limited quantities. Craft brewers are small, regional brewers.


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Heavenly Dining- Abundant Meal.
When Jesus prepares a meal, a little is more than enough. Even when feeding more than 5,000 people with only, "five loaves of bread and two fish" Luke 9:13 (NIV), there were more than 12 baskets of leftovers. When we look heavenward for nourishment, we are always filled.
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Check out what's hot online right now.
Hot video
In the annual battle for best Super Bowl TV ad, perennial contender godaddy.com has released a sneak peek at their offering.
Trending topic: January Jones hair loss
Actress January Jones – who stars in "Mad Men" – said at the Screen Actors Guild Awards that she is losing her hair. Jones said it appears that it's falling out "in clumps" because of excessive hair dyeing.
GateHouse News Service


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What's the point of trying to reason with the dirty foreigners? So we've lost status around the world, eh?
Well maybe that's because we can't finish what we started.
Maybe this guy can. no more wimps for president!
There's only one way to win back respect for America and this guy knows the way.
Oh, by the way, I've broke over 5 million hits this week, so thanks loads, everybody!


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Crosswords Printables > Themed Crossword Puzzles > Bible Crossword Puzzles > 12 Spies Sent into Caanan Crossword Puzzles
12 Spies Sent into Caanan Crossword Puzzles
We hope you enjoy your crossword puzzle that you have selected! Remember to check our more of our Thanksgiving Crossword Puzzles and share them with your friends. If you are a parent or teacher, print as many as you'd like and use them for extra learning practice and fun activities!
How well do you know your Old Testament? Test your knowledge with this free themed crossword puzzle about the 12 spies in the Bible's early books.
This crossword consists of a few words Across(A) and a few words Down(D). Review the clues for each word and fill in the corresponding boxes with the letters that spell out the word!
Download or Print PDF!
|See More Bible Crossword Puzzles


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حكماتو الكمرا 😜
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Designer - MariR Designs
My name is Mari Romualdo. I graduated in law, but I dedicate myself exclusively to my home and my family. I am 54 years old, I'm brazilian girl and have a child 15 years of age.
I started in 2006 to research and work with scrapbook. It was love immediately. I love photography, image editing, reading, movies and television shows since his teens and have an absolute passion for all arts and crafts. Hope you enjoy my products.


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Monday, February 8, 2010
Coming Soon! More Useless Blogs!
I feel kind of confined by HoseMaster of Wine. Sure, it's brilliant comedy and, well, there's not a lot of that out there in the wine blogosphere, though LusciousLushes is hilariously inept. And sure I've won the Nobel Prize, a Pritzker, several Humanitarian awards, a People's Choice, an NBA MVP, and a coveted Psoriasis Society Biggest Flake Award, but I'll be honest, there are so many other bloggers I want to be, so many different kinds of blogs that I admire and want to emulate. So I'm thinking of starting a few more wine blogs. Hey, I'm basically unemployed, I've got the time, and, besides, as so many so aptly demonstrate, they don't take much work or thought.
I love the blogs that just review the stupid and virtually worthless samples that are sent to them. Listen, friends, here's a clue: When the cost of shipping the bottle exceeds the bottle's price, don't review it! It's crap, and the winery is fishing for a fool to slap their label on their wine blog, and you're the bottom feeder they've hooked. But I love the concept. Post after post about truly mediocre wine, every one praised as though it's the Second Coming of Yquem. I get the wine for free, I steal descriptions from the marketing material included with the bottle, and then I match it with a poem or a song or a porn movie, and, voila, I have a successful wine blog. One thing about the Internet--no shortage of stupid people reading it.
"The Ironstone 2006 Cabernet Sauvignon would be perfect with Vivid's 'The Hurt Licker.'"
If cyberspace can be said to be wasted, this species is the Cheech and Chong of wine blogs. I'd model mine after WineHarlots (please, for the love of God, I'm begging you, believe me, you MUST believe me, do NOT go there), which, if there were any justice, would be ground up and put in cow horns and buried in a BioDynamic vineyard. Here two sisters, equally ignorant about wine, review samples that seem to have been sent to them instead of The Dollar Store. Not only do they wax rhapsodic about these dogs in prose that is surely computer generated and stiffer than the lead actor in "The Hurt Licker," they feel the need to tell you what closure the bottle sports (no doubt because you wouldn't want to rush out and purchase a fraudulent bottle of this unmitigated piss), and they match the wine with music. So I'm supposed to believe that two women with very little in the way of discernment when it comes to wine know music? And, hell, am I supposed to chug the bottle in the four minutes it takes to play your crappy iPod selection, or do I just play it over and over until the wine is finished and my sanity deeply injured?
There are countless blogs out there like WineHarlots. I see them as the Special Olympics of Tasting Notes. I want in. I think WineBottomFeeder will be a huge hit.
So this would be my blog where I list lots of events going on in the wine world and act like I'm doing a public service by writing about them, tweeting about them, and posting them on my Facebook page, so I am generally responsible for their success. This gives me great feelings of self-importance. I get an email from someone putting on a wine-related event, I jot down the info on my blog, make it sound like it is of critical importance for everyone who loves wine to participate or read about it, and, there, I've got me a blog! You can do these posts in your sleep, and lots of bloggers do. The lastest conference on Social Media and Wine, you should go!! (Hey, if Social Media is so powerful, why do we have to have a conference? Can't we just do it from home, at our computers, on our iPhones? Do we have to go to some dumpy hotel to listen to Alder and Andy and Joe and Steve tell us how much influence they have? I already know how much influence they have--look at the dumpy hotel ballroom they're speaking in.)
Of course, a blog like this demands that you post five days a week. So keep those PR notices coming! Otherwise, I might actually have to have something to say. Have a stupid wine event? I'll publicize it! And then I'll tweet about it so that my 674 followers on Twitter can feel like they're important, that they're the very lifeline of existence without whom information simply does not exist, and I'll post it on Facebook because, well, that's where I go to reassure myself I have friends, really good friends, friends who would do anything for me. All of this proves I am important in the wine business, and, as we all know, importance translates into expertise. Not the other way around.
OK, I'm a little old to start this blog, but I can pretend. I play the part of a frustrated writer (my friends always tell me I'm so good at writing I should start my own blog! I wrote for my high school newspaper, you know) who has discovered his passion for wine. Join me on my journey of discovery! Why? Well, because it is so interesting and I have so much to say. Together we'll explore wine. And none of that icky European stuff, and nothing that costs much money. Frankly, tasting all of those expensive and great wines just ruins your palate and you can't really enjoy the kind of wines you can afford, so why bother? I've had lots of wines under $15 that I'd rate over 95 points! Why? Hell, it's easy when you don't know anything. That's why they call it a journey. But wouldn't you much rather enjoy a $12 bottle that gets 95 points than a $125 bottle that gets 96? And you can! Just join me as I discover the amazing world of wine! Here are just a few of the things you'll learn along with me:
Did you know Pinot Grigio and Pinot Gris are the same grape! They mean "old pinot" in Italian and French.
Did you know not all Gewurztraminer is sweet? I know! Neither did I? And the "w" is pronounced like a "v," just like in Der Wienerschnitzel--and they're a perfect wine and food match!
Did you know professional wine people spit wine out when they taste it?! Not me. That's just stupid.
29 comments:
- Puff Daddy said...
Wine Harlots or Brix Chicks?
Which is your favorite girl band?
I prefer solo singers myself.
- February 8, 2010 at 11:04 AM
- Puff Daddy said...
Speaking of solo singers.
Do you give advice for the lovelorn? I mean, this silly blog cannot be all you do?
Well, HMW, here is my problem. I have this thing for this chick named Sam. And I think I am getting along fine with her, but she keeps flrting with some Ron guy, and then she introduces to me to her friend Alice and tells me to play nice with Alice.
Do you think Sam still loves me?
- February 8, 2010 at 11:07 AM
- Puff Daddy said...
OK, HMW, I won't start a blog until I have checked out its name with you. It's just that I am running out of wine and can't wait for those sample of $7 Chilean Carmenere to come flooding in. Oh, and will someone please send me Gruner Veltliner? I have to wash my hubcaps.
- February 8, 2010 at 11:09 AM
- Samantha Dugan said...
Mr. Puff Daddy Sir,
Might I just point out that it was YOU that had your head spun by Alice. You were the one that was so bold as to tell me that you were going to cheat on me with Alice, broke my heart you brute....I thought I was your special girl, (you must picture big sad eyes and a pouty lip here).
I don't flirt, was born without the gift of purring sweet nothings, flicking little snips of wit and sass that seem to land on the intended in such a way that it leaves them feeling as if I've taken a big, wet, groan indicing bite out of their neck. So sorry, if you saw flirting...wasn't me, (helps to picture me walking away and looking over my shoulder while saying this).
And yes, I still love you!
- February 8, 2010 at 11:52 AM
- Samantha Dugan said...
Oh, and great post Ron! Keep up the good work. You know, you are getting to be kind of funny and junk...you just might give the Heimoff a run for his money....
Backing away
Covering my hide
Sending you kisses...
- February 8, 2010 at 11:58 AM
- Thomas said...
Who the hell is this Ron Washburn anyway? Why does he think he haz sumething to saye? And he can't even rite. I don't lik hiz blog.
- February 8, 2010 at 12:49 PM
- Wine Harlots said...
Thanks for the kind words, Ron.
You may want to apply for Rahm Emanuel's job, I hear it might be opening up and you'd be perfect.
- February 8, 2010 at 2:26 PM
- mia said...
Is there a logic in bashing other bloggers? I prefer to read about the wines you enjoy then the less than professional comments.
Mia Frank
- February 8, 2010 at 3:16 PM
- CabFrancoPhile said...
Ron, there are a few more blogs you might consider starting. The Sample Slut, where your expertise is based on receiving free bottles. Selling t-shirts and etched glasses with your catch phrase "I swallow all the swill they send me so you won't know what's shit . . . ."
Or, Wanting To Be a Wino. Where you write up polite reviews on everything you receive, being especially in awe of expensive wines. Your palate education will be at the whims of the marketers--just the way the want it.
- February 8, 2010 at 4:02 PM
- Ron Washam said...
Puff Daddy,
My favorite girl band is Adam Lambert, whose family owns Lambert Bridge, don't they? And, no, I do not dispense advice to the lovelorn. I always keep my opinions to myself. As for starting a blog--well, most people start a blog in an hour. It's been seven months for you. I'll believe it when I see it. Though I'm thinking if it's not called Puff Daddy of Wine I may start one with that name.
My Gorgeous Samantha,
Hmmm. I wonder what a Sans Dosage parody would read like...
I adore you, my little troublemaker.
Ms. Wine Harlot,
I picked on you but I could easily have picked on fifty other blogs doing the same schtick. I'm afraid the HoseMaster was in a foul mood this morning when he wrote this. But at least I spelled your name right; and thank you for providing a link to your blog with your comment so that others can judge whether I was too harsh. Of course I was, it's satire, in the loosest definition of the word. Was it mean, sure. Was it unjust? Just one bozo's opinion.
You're in the wrong place. This is the wine blogosphere. We don't get paid. None of us is professional. Unless you count getting bribed with free wine as professional, in which case we're, well, harlots, the world's oldest profession.
"Bashing" other bloggers isn't about logic, Mia. The sort of nonsense I do here is about using satire as the weapon it is intended to be. The point wasn't the bashing, the point was expressing a view rarely, if ever, expressed in our little corner of the Internet--that most wine blogs are unbelievably idiotic. I just like to make it a more interesting opinion than that.
Cab Frank,
One is clearly too many blogs for the ol' HoseMaster.
- February 8, 2010 at 6:52 PM
- Eric V. Orange said...
Ha. Let me emphasize that...HA HA!
I keep coming back for more. I can't help it.
Keep at it Ron..or..is that Rahm?
- February 8, 2010 at 7:50 PM
- Arthur said...
A long time ago, in a blogging galaxy far, far away, wine bloggers enjoyed being skewered by a blog called wine-ing 2.0 and almost wanted that dubious honor.
What changed?
- February 8, 2010 at 7:59 PM
A friend and good pal from the Department of Repetitiveness and Redundancy pointed out, with respect to this topic, many and most wine blogs are, uh, useless.
Are the Bricks Chix, at least, well stacked? Maybe that's why Sir Puffnstuff is a fan of their Lodi Klinkers??
Hosemaster, Sir...
If you are serious about posting more wine blogs...
If you had one evaluating wine made from grapes grown within walled vineyards... CLOS-MASTER of WINE
If you post on dealing with racking wine using gravity... FLOWS-MASTER OF WINE
Write one evaluating solely the aromatics of wines: NOSE-MASTER OF WINE
Issue periodic reviews of wines vinified in lagares and from grapes crushed by feet: TOES MASTER OF WINE
A blog with witicisms and reviews of a prominent St. Estephe chateau: COS-MASTER OF WINE
A wine blog to cure insomnia (which many do already): DOZE-MASTER OF WINE
If you're going to mimic many blogs where the authors attempt to appear knowledgeable about wine: POSE-MASTER OF WINE
A wine blog dealing with one particular Northern Rhone appellation (Sam will love this one): CROZES-MASTER OF WINE
A wine blog emcompassing Eisweins from Germany: DER FROZE-MASTER OF WEIN
If yuo choose to write a wien blgo fro dyslexics: TRANSPOSE MASTER OF WINE
- February 8, 2010 at 9:45 PM
- Arthur said...
Don't forget: SootInMyWine.com - specializing in smoke-tainted wines...
- February 8, 2010 at 10:25 PM
- Puff Daddy said...
- February 8, 2010 at 11:08 PM
- Samantha Dugan said...
Troublemaker...moi?! C'mon, not even close...but if it is trouble you seek, call me.
I've been waiting for a Sans Dosage parody for months, bring it Hose Boy...I can take it. If it stings too much I will see if My Charlie will beat you up for it. Would love to have you take a bite outta me, as it were...
- February 9, 2010 at 3:36 AM
- Thomas said...
Let me see: around 1,000 wine blogs are in circulation...it's so obvious what follows that thought that nothing more needs to be said.
Charlie has the right idea, thus far. Do not succumb ole man. Don't be pressured into doing it. But if you must, I'll sell you my blog for a pittance, which will then finally make the drivel that I've typed over the years pay off.
- February 9, 2010 at 6:53 AM
- Puff Daddy said...
The problem with selling things is that they have a market value. Care to estimate the market value of your blog?
Now Sam's blog--that another thing. I get to look at pictures of feet, and that's way better than not looking at picture of pretty girls now that Ron has eschewed that subject.
If I ever do a blog, here is my first promise. No pictures of my feet; pictures of Sam's feet instead.
- February 9, 2010 at 7:55 AM
- Samantha Dugan said...
My feet?! Then why did you have me send you all those glossy pictures of my boobs?! Dang it Charlie....
- February 9, 2010 at 8:31 AM
Puff Daddy, Sir: If you're going to write a wine blog specializing in "foot" photos, you'll have to move to Piedmont.
One can only imagine Samantha Avec Dosage...still bubbly, but with less 'bite.' BRUTal?
SECsy? I think the Hosemaster is being MAGNUMinous by not barbing SSD. Besides, there are many websites so deserving of his sharp lampoon (or is it a harpoon?).
- February 9, 2010 at 8:44 AM
- Puff Daddy said...
I should live so long.
- February 9, 2010 at 8:46 AM
My most recent comment to Sam, not Anon1, who should keep his feet to himself.
- February 9, 2010 at 8:48 AM
- Ron Washam, HMW said...
Hey Gang,
Gee, remember when Samantha used to come here to flirt with ME?
Don't you people sleep?
Damn blog is turning into FaceHoseMaster of Wine. Hey, I have 41 Friends!
- February 9, 2010 at 9:08 AM
- Thomas said...
You haven't 41 friends, you have numeric dyslexia...
I said I'd sell the blog for a pittance--you want me to embarrass myself and name a price to all 14 people reading?
- February 9, 2010 at 10:25 AM
Little Ronnie
Time for you to really get serious about something in your life. This wine stuff is way too much fun.
Jimmie Schnipke
- February 9, 2010 at 12:26 PM
Little Ronnie ??
I like that.
And it is so nice that little Ronnie has a friend named little Jimmie.
By the way, did you know that Ekpinhcs is Schnipke spelled backwards? Neither did I.
And you also probably did not know that you can get schnipkes from working for bubkes.
- February 9, 2010 at 1:16 PM
- Erin said...
Dear Mister,
As always, I adore you, and my silly blog is on your pinch list, and for that I also am grateful, even though it's really quite silly.
I do believe you're my wine blog saviour but don't get a big head yet, Heimoff just lost that title and look where he ended up! (Insert song lyrics and wine pairing here.)
Love, Erin
- February 9, 2010 at 9:59 PM
- The Wine Mule said...
Do you think Tom Wark has gotten crazier since he stopped smoking?
I would like to take this opportunity to thank you and thousands of other people for not visiting my blog. It is already both useless and boring. If anybody actually read it, I'd probably feel obliged to, you know, apply myself to it.
- February 21, 2010 at 10:20 AM
- helen said...
Cheers for the compliment. Actually I don't really know how to do build my own modules unfortunately. What I'll do at some point in the near future is take the site to another town in the UK and when I do that I'll build a module for it. I'm still kind of learning the ropes when it comes to Dru pal.
- October 18, 2010 at 5:18 AM


text:
I'm a mom trying to raise four kids to be courteous, caring adults so I figure that I ought to at least practice what I preach and be polite--even under duress. But there are those times when you get pushed to the brink of sanity you know?
Tell me that I'm not the only one ready to pass a moratorium on political pollsters? It used to be that I'd get a call or two asking who I was likely to vote for but now . . . NOW they all start out months ahead of V-day with "I'd like to ask you a couple questions, it will only take a moment . . . " and then they proceed to ask seventy or eighty questions that take so long to answer that by the time I finish the polls are closed and the election's been called.
Maybe I'm odd but "a couple" means two. TWO. As in, "Have a COUPLE cookies" or "They are a COUPLE" or "It costs a COUPLE of bucks." This translates into: "Are you registered to vote?" followed by "Who are you most likely to vote for?"
Not "Given the incumbent candidate's views on abortion, the environment, NAFTA, the price of oil, domestic violence, apartheid, Volkswagen bugs, mullets, Paris Hilton and bologna are you definitely unlikely, really unlikely, somewhat unlikely, unlikely, kind of likely, pretty likely, mostly likely or completely likely to support their opponent in the upcoming election?"
"Uh, can you repeat the question?"
The thing is I'm too darn nice to get uppity with them and object. I should just refuse to take the poll from the very beginning but I'm held back by the guilt I feel at the possibility that maybe if I refuse to take a poll I'm jeopardizing the entire political process and shaking the foundations of freedom and democracy all over the world. That and I can't ever bring myself to hang up on a person.
But this last call did it and I've decided that I'm never again going to take a poll. Never--and you've got that in writing. If you want my opinion, submit it by email or better yet, visit my blog (I'm always giving out an opinion there).
You see they're getting sneakier because they're not just trying to find out my opinion they're trying to influence my opinion and I'm onto them like lipstick on a hockey mom. Or is that lipstick on a pit bull? I get them mixed up. I mean, I may not have a rock-solid political platform here but darn it, it's mine and I'm not so stupid that I can't see where all those leading questions are taking me.
"Given candidate X's recent vote on bill 476 which will promote strip mining as well as minors stripping can you in good conscience still support her opponent?"
"What if, in the course of the campaign, it were proved that candidate Y were a child-loving bibliophile? Would that change your vote?"
And my personal favorite, "Have any of these questions changed your opinion?"
The last poll I took like this started out innocuously enough but after five minutes of questions that were repetitive, partisan and leading I finally got gutsy enough to ask "You said it was only a couple of questions, how much longer will this take?" I was assured we were at the end but the questions continued and continued until I finally got irritated enough to interrupt (yes, I actually interrupted!) and say, "I'm sorry but I don't have any more time. Thank you for calling."
I told Grace that in the future any pollsters would be directed to her. They can talk with her--probably the only person in the world who has more stamina with a phone receiver in her hand and could outlast them in a phone call-to-phone call smack down. She'd never get tired of talking in a million years.
But the ultimate? The absolute limit? A couple weeks ago the kids had received coupons for personal pizzas from Pizza Hut at school and had been begging me to take them to Pizza Hut so they could cash them in. We called ahead for take-out, they picked up the pizzas, went home and ate them. End of story. Completely non-interesting. Except that . . .
A couple days later (a couple meaning TWO) I got a call from a person asking if I would be willing to answer a couple of questions about my experience ordering from Pizza Hut.
Suspicious but once again, not wanting to be rude I said, "Okay? . . . ."
Now maybe I'm weird but somehow knowing that I could go and pick up some pizzas, make my way to the safety and security of my home and then have them track me down to hound me about the purchase didn't sit well. It's not like I want to order pizzas under an alias or anything but where's the privacy people?? I just want my pizzas, let me eat them in peace.
She proceeded to question me about whether I physically went into the restaurant to pick up said pizzas, what toppings I had on my pizzas, whether I chewed them on the right side or left side of my mouth, whether I used unleaded or diesel, whether I'm a natural blond and whether I'd ever considered adopting a badger before finally asking "How likely are you to order pizza from Pizza Hut again in the future?"
I'd had enough. As if being hounded by political pollsters trying to get me to vote for their guy wasn't enough, as if pre-recorded messages from our local school board reps cutting into family activities weren't enough, as if being interrupted at dinner every other night to see if I would sponsor blind children to go to the movies weren't the limit, NOW Pizza Hut is tracking me down to grill me about my choice of pizza toppings?? I just wanted some pizza, dang it! Is that so wrong?
I took a breath and said something to the effect of, "Well you know, I've always thought Pizza Hut was pretty good--I've eaten there lots of time and had plans to come back as often as my cravings called but if I'm going to walk in, pick up a pizza, then be phoned by Pizza Hut later and hassled with lots of questions about the whole thing I don't think I'll be going back ever again. The relationship is over--I'm through. I prefer a silent, one-night's stand pizza experience."
So don't even try calling me again Pizza Hut because on Tuesday? I'm voting for Little Caesar's.
Sponsored by Pak Naks--Decorate your stuff with these adorable rubber charms.
Technorati tags: polling, telemarketers,


text:
I received this photo from Ryan MacMicahel who writes a vegetarian themed blog called Veg Blog. It's of his daughter Rasine who spontaneously chose to pick up and read a copy of Hardcore Zen from her dad's bookshelf. Maybe she will learn to be as angry and hateful as I am! Wouldn't that be sweet?
I was reading the comments section of the last post sorta scratching my head about why this whole "Brad is so angry" business had started up again. Then I remembered that I had called Genpo Roshi a scumbag. I guess that makes people think I'm angry at him. I'm not angry at him. I just think he's a scumbag for deliberately lying to people about Zen practice in order to make himself rich, that's all. You don't need to be angry at someone to feel that way about them. Whatever.
Oh and to the commenter who thought the bird in the photo I posted last time was "about to take a shit in that girl's mouth." That's no girl in the picture, it's me! And Sunny was such a cool bird that he would not take a crap on you. He'd fly away somewhere else and do it. We never taught him that, but he somehow worked it out that we didn't like him pooping on us so he stopped.
Oh & before I begin, another reminder that the usual zazen at 10 am this Saturday July 18th at 237 Hill St. Santa Monica 90405 will happen & I'll be there. But don't park in the lot because it's being used that day for some event at the church. This will be a regular sitting not one of the all-day things. The all-day one will be on July 25th. Sunday July 19th at 11am I'll host zazen at Against The Stream, 4300 Melrose Ave LA 90029.
I've been thinking about the subject of ego lately because it keeps coming up in my writing for the new book I'm working on. When Eastern religions, including Buddhism, first started washing up on our shores the buzz on the streets said that meditation was all about giving up, transcending or sometimes even destroying the ego.
There is some truth to that. But a lot of times the word "ego" is used as a synonym for self-esteem. In fact if you look it up using the thesaurus tool on MS Word that's one of the synonyms that comes up. It's often paired with the word hubris, which means excessive pride.
In some of the interviews John Lennon gave in the early Seventies you can see that he, for one, picked up on this meaning of the word ego. So he spent a lot of time cutting himself down, destroying his self-esteem and the natural pride he felt in his work. I'm sure a lot of people did this and probably are still doing it.
This is one reason why I avoid using the word "ego" in this context. It's unhealthy to try and get rid of your self-esteem and there is no sin in pride as long as it doesn't get out of control.
Ego, in the sense that it's used in Buddhism, is not self-esteem. In fact, your ego can often be enriched even better by a negative self image than a positive one. I am worthless, I am ugly, nobody loves me. All of this just builds it up even more.
Also, in a somewhat related topic is the idea of using positive thoughts to try and combat negative ones. This never works either. Because every thought includes its opposite. White is white precisely because it's not black. "I am a good person" is what it is because it contrasts with "I am not a good person." And so on and on and on and on. It's all just more thought.
If you're absolutely drowning in negativity maybe the contrast can lift you up a little. But it's not going to hold for long. The trick is to see that none of the ways you characterize yourself are ultimately any better than any other.


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