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CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology CurriculumLearning ObjectivesStudents will be able to: Week 1-4: Fundamentals of Science and Biology
- List the major processes involved in scientific discovery
- List the different types of scientific studies and which types can establish causation
- Design experiments with appropriate controls
- Create and evaluate phylogenetic trees
- Define taxonomy and phylogeny and explain their relationship to each other
- Explain DNA sequence divergence and how it applies to evolutionary relationships and DNA barcoding
- Define and measure biodiversity and explain its importance
- Catalog organisms using the morphospecies concept
- Geographically map organisms using smartphones and an online mapping program
- Calculate metrics of species diversity using spreadsheet software
- Use spreadsheet software to quantify and graph biodiversity at forest edges vs. interiors
- Write a formal lab report
- Extract, amplify, visualize and sequence DNA using standard molecular techniques (PCR, gel electrophoresis, Sanger sequencing)
- Explain how DNA extraction, PCR, gel electrophoresis, and Sanger sequencing work at the molecular level
- Trim and assemble raw DNA sequence data
- Taxonomically identify DNA sequences isolated from unknown organisms using BLAST
- Visualize sequence data relationships using sequence alignments and gene-based phylogenetic trees
- Map and report data in a publicly available online database
- Share data in a formal scientific poster
A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research ExperienceLearning Objectives
- Students will be able to evaluate the strengths and weaknesses of data.
- Students will be able to employ prior knowledge in formulating a biological research question or hypothesis.
- Students will be able to distinguish a research question from a testable hypothesis.
- Students will recognize that the following are essential elements in experimental design: identifying gaps in prior knowledge, picking an appropriate approach (ex. experimental tools and controls) for testing a hypothesis, and reproducibility and repeatability.
- Students will be able to identify appropriate experimental tools, approaches and controls to use in testing a hypothesis.
- Students will be able to accurately explain why an experimental approach they have selected is a good choice for testing a particular hypothesis.
- Students will be able to discuss whether experimental outcomes support or fail to support a particular hypothesis, and in the case of the latter, discuss possible reasons why.
The Science Behind the ACTN3 PolymorphismLearning ObjectivesThis article accompanies the lesson "The ACTN3 Polymorphism: Applications in Genetics and Physiology Teaching Laboratories." Learning objectives for the lesson include:
- Test hypotheses related to the role of ACTN3 in skeletal muscle function.
- Explain how polymorphic variants of the ACTN3 gene affect protein structure and function.
- List and explain the differences between fast twitch and slow twitch muscle fibers.
- List and explain possible roles of the ACTN3 protein in skeletal muscle function.
- Find and analyze relevant scientific publications about the relationship between ACTN3 genotype and muscle function.
- Formulate hypotheses related to the relationship between ACTN3 genotype and skeletal muscle function.
- Design experiments to test hypotheses about the role of ACTN3 in skeletal muscle function.
- Statistically analyze experimental results using relevant software.
- Present experimental results in writing.
Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant...Learning Objectives
- Describe how cells can produce proteins at the right time and correct amount.
- Diagram a bacterial promoter with −35 and −10 elements and the transcription start site.
- Describe how mutational analysis can be used to study promoter sequence requirements.
- Develop a promoter mutation hypothesis and design an experiment to test it.
- Successfully and safely manipulate DNA and Escherichia coli for ligation and transformation experiments.
- Design an experiment to verify a mutated promoter has been cloned into a destination vector.
- Design an experiment to measure the strength of a promoter.
- Analyze data showing reporter protein produced and use the data to assess promoter strength.
- Define type IIs restriction enzymes.
- Distinguish between type II and type IIs restriction enzymes.
- Explain how Golden Gate Assembly (GGA) works.
- Measure the relative strength of a promoter compared to a standard promoter.
Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant GerminationLearning ObjectivesStudents will be able to:
- identify when germination occurs.
- score germination in the presence and absence of GA to construct graphs of collated class data of wild-type and mutant specimens.
- identify the genotype of an unknown sample based on the analysis of their graphical data.
- organize data and perform quantitative data analysis.
- explain the importance of GA for plant germination.
- connect the inheritance of a mutation with the observed phenotype.
Teaching Biodiversity with Museum Specimens in an Inquiry-Based LabLearning ObjectivesStudents completing this lab module will:
- Learn how to appropriately handle and measure museum specimens.
- Develop the necessary statistical skills to analyze museum specimen data.
- Become familiar with how to search an online museum database and integrate supplemental data with their own dataset.
- Strengthen scientific communication skills by presenting research to their peers.
- Demonstrate ability to investigate scientific questions and address obstacles that occur during data collection and integration.
- Increase proficiency in managing and using large datasets for scientific research.
- Make connections between natural history knowledge and morphology of organisms in developing and testing hypotheses.
Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model OrganismLearning ObjectivesStudents will:
- demonstrate understanding of the concept and details of experimental design.
- perform an organic lipid extraction to determine total lipid content.
- quantify enzyme activity, as well as triglyceride, glucose, and glycogen concentrations.
- organize their collected data into spreadsheets for statistical analyses.
- interpret the results to gain insight on the varying effects exercise has on an organism's physiology.
- graphically present their results so that trends can be easily identified.
A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO2?Learning ObjectivesStudents will be able to:
- Apply findings from each week's lesson to make predictions and informed hypotheses about the next week's lesson.
- Keep a detailed laboratory notebook.
- Write and peer-edit the sections of a scientific paper, and collaboratively write an entire lab report in the form of a scientific research paper.
- Search for, find, and read scientific research papers.
- Work together as a team to conduct experiments.
- Connect findings and ideas from each week's lesson to get a broader understanding of how plants will respond to higher levels of CO2 (e.g., stomatal density, photosynthetic/respiratory rates, foliar protein concentrations, growth, and resource allocation).
Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeographyLearning ObjectivesStudents will be able to:
- Estimate phylogenetic trees using diverse data types and phylogenetic models.
- Correctly make inferences about evolutionary history and relatedness from the tree diagrams obtained.
- Use selected computer programs for phylogenetic analysis.
- Use bootstrapping to assess the statistical support for a phylogeny.
- Use phylogenetic data to construct, compare, and evaluate the role of geologic processes in shaping the historical and current geographic distributions of a group of organisms.
A new approach to course-based research using a hermit crab-hydrozoan symbiosisLearning ObjectivesStudents will be able to:
- define different types of symbiotic interactions, with specific examples.
- summarize and critically evaluate contemporary primary literature relevant to ecological symbioses, in particular that between hermit crabs and Hydractinia spp.
- articulate a question, based on observations of a natural phenomenon (in this example, the hermit crab-Hydractinia interaction).
- articulate a testable hypothesis, based on their own observations and read of the literature.
- design appropriate experimental or observational studies to address their hypotheses.
- collect and interpret data in light of their hypotheses.
- problem-solve and troubleshoot issues that arise during their experiment.
- communicate scientific results, both orally and in written form.
A virtual laboratory on cell division using a publicly-available image databaseLearning Objectives
- Students will name and describe the salient features and cellular tasks for each stage of cell division.
- Students will predict the relative durations of the stages of cell division using prior knowledge and facts from assigned readings.
- Students will describe the relationship between duration of each stage of cell division and the frequency of cells present in each stage of cell division counted in a random sample of images of pluripotent stem cells.
- Students will identify the stages of cell division present in research-quality images of human pluripotent stem cells in various stages of cell division.
- Students will quantify, analyze and summarize data on the prevalence of cells at different stages of cell division in randomly sampled cell populations.
- Students will use data to reflect on and revise predictions.
CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate studentsLearning ObjectivesWeek 1: CRISPR design
- Locate the coding sequence, flanking sequence, protein product, and characteristics of a given gene from the Saccharomyces Genome Database (https://www.yeastgenome.org/).
- Design and defend the design of guide RNA and single stranded template for DNA repair in CRISPR/Cas9 gene editing studies to generate Saccharomyces cerevisiae auxotrophic mutants.
- Describe the qualities of the vector, pML104, that allow replication and selection in bacteria and yeast as well as allow expression of necessary factors in CRISPR/Cas9 genome editing, including Cas9 and sgRNA.
- Describe the rationale of and perform procedures necessary for cloning a small cassette (i.e., sgRNA gene) into a vector (i.e., pML104) including; restriction digest, annealing of DNA strands, removal of 5' phosphates, ligation, and transformation.
- Recognize and design appropriate controls for cloning procedures such as ligation and transformation.
- Describe the method of polymerase chain reaction (PCR), including the rationale for essential components of a reaction mixture and thermal-cycling conditions.
- Locate the binding sites of and design primers for PCR, then report the expected size of the amplification product.
- Describe and perform isolation of plasmid DNA from E. coli.
- Describe the rationale for and perform procedures to transform yeast, including the essential components of a transformation mixture and conditions necessary for transformation.
- Describe the basic conditions required for cultivating yeast.
- Describe the rationale for and perform agarose gel electrophoresis of a given size of DNA.
- Analyze DNA separated by agarose gel electrophoresis, including size estimation.
- Recognize and describe the qualities of a template for DNA repair that allows efficient DNA repair.
- Design an experiment to determine auxotrophic phenotypes.
- Predict the outcome of multi-step experiments.
- Recognize and describe conditions necessary for growth of E. coli and S. cerevisiae.
- Qualitatively and quantitatively analyze scientific data from scientific experiments, including bacterial and yeast transformation, agarose gel electrophoresis, extraction of plasmid DNA from bacteria, PCR, and auxotroph phenotypic analysis.
- Communicate science to peers through maintenance of a laboratory notebook, verbal communication with group members, and writing of a formal laboratory report written in a format acceptable for journal publication.
- Troubleshoot scientific protocols by identifying procedures that are prone to error, comparing recommended protocols to actual procedure, and using positive and negative controls to narrow the location of a potential error.
- Communicate specific potential or actual uses of CRISPR/Cas9 in science and/or medicine.
- Use various bioinformatics approaches to analyze macromolecular primary sequence and structure.
- Illustrate how DNA is replicated and genes are transmitted from one generation to the next in multiple types of organisms including bacteria, eukaryotes, viruses, and retroviruses.
- Define what a genome consists of and how the information in various genes and other sequence classes within each genome are used to store and express genetic information.
- Explain the meaning of ploidy (haploid, diploid, aneuploid etc.) and how it relates to the number of homologues of each chromosome.
- Predict the effects of mutations on the activity, structure, or stability of a protein and design appropriate experiments to assess the effects of mutations.
- Predict the growth behavior of microbes based on their growth conditions, e.g., temperature, available nutrient, aeration level, etc.
- Discuss the benefits of specific tools of modern biotechnology that are derived from naturally occurring microbes (e.g. cloning vectors, restriction enzymes, Taq polymerase, etc.)
- Accurately prepare and use reagents and perform experiments.
- When presented with an observation, develop a testable and falsifiable hypothesis.
- When provided with a hypothesis, identify the appropriate experimental observations and controllable variables.
Dynamic Daphnia: An inquiry-based research experience in ecology that teaches the scientific process to first-year...Learning ObjectivesStudents will be able to:
- Construct written predictions about 1 factor experiments.
- Interpret simple (2 variables) figures.
- Construct simple (2 variables) figures from data.
- Design simple 1 factor experiments with appropriate controls.
- Demonstrate proper use of standard laboratory items, including a two-stop pipette, stereomicroscope, and laboratory notebook.
- Calculate means and standard deviations.
- Given some scaffolding (instructions), select the correct statistical test for a data set, be able to run a t-test, ANOVA, chi-squared test, and linear regression in Microsoft Excel, and be able to correctly interpret their results.
- Construct and present a scientific poster.


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Borage (Blue)
Borago officinalis
Bright blue flowers attract bees and have a cucumber-like flavour. Leaves contain calcium and potassium and can be finely chopped (to mitigate the rough texture) and added to salads along with the flowers. They also make a delicious cooked green, either briefly boiled or sauteed. Keep plants well watered and feed with a nitrogen rich fertiliser if aiming for leaf production, and keep flower heads cut back. Some studies show borage can kill and inhibit the growth of cancer cells and there are many other medicinal claims for the plant, including beneficial effects on the mind and dispelling melancholy. An edible blue dye can also be made from the flowers. Said to accumulate calcium, silica and potassium. Height to 60cm. 9cm pot certified organic plant.


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予定表 -詳細情報-
|'39 三菱一式陸上攻撃機の初飛行
|毎年 10月
最初の予定 2005年 10月 23日 (日曜日)
|2008年 4月 27日 (日曜日)
投稿日時: 2014-12-17 11:47 更新日時: 2014-12-17 11:47
登録日: 2014-9-29
投稿数: 72
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March 16, 2013
'LA Times' reports the US is collecting intelligence that would be used for possible drone strikes on extremists rebels.
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ABC News Supreme Court Nomination Poll, July 1991 (ICPSR 9612)
Version Date: Sep 18, 2007 View help for published
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ABC News
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This survey focuses on the nomination of Clarence Thomas to the Supreme Court of the United States. Respondents were asked if they approved of the way the Supreme Court was doing its job, if the Supreme Court was becoming more conservative in its decisions, if they approved of Thomas's nomination to the Supreme Court, if the Senate should only consider Thomas's background and qualifications or if it should consider his political views as well, and if Thomas should be confirmed only if he indicates that he would vote to overturn/uphold the Supreme Court's 1973 ruling that allowed a woman to have a legal abortion for any reason during the first three months of pregnancy. Respondents also were questioned about White House Chief of Staff John Sununu's use of government and corporate planes while he was not on official White House business. Background information on respondents includes political alignment, education, age, race, sex, and state/region of residence.
Citation View help for Citation
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A weight variable is included that must be used in any analysis.
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Households were selected by random digit dialing. Within household, the respondent selected was the adult living in the household who last had a birthday and who was at home at the time of the interview.
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Adults aged 18 and over living in households with telephones in the 48 contiguous United States and the District of Columbia.
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telephone interviews
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- ABC News. ABC NEWS SUPREME COURT NOMINATION POLL, JULY 1991. Radnor, PA: Chilton Research Services [producer], 1991. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2007-09-18. http://doi.org/10.3886/ICPSR09612.v1
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text:
Environmentalists say Shenandoah National Park at risk
By Brian Wheeler
Charlottesville Tomorrow
Wednesday, July 18, 2012
State and local environmental protection advocates gathered in Darden Towe Park on Wednesday to warn about federal legislation that they said poses a clear and present danger to the Shenandoah National Park and other wilderness lands in Virginia.
Activists said unless the bills pending in Congress are stopped, wilderness areas in Virginia will be threatened by road building, development and resource extraction.
Charlottesville City Councilor Dede Smith said public parks are "some of our nation's greatest treasures."
"Here in Virginia we are lucky enough to have one of our crown jewels in our own backyard," said Smith. "More than one million people come to the Shenandoah National Park every year for its spectacular vistas, its quiet hollows and cascading waterfalls."
The press conference was timed with the release of a report by Environment America, entitled "Trashing our Treasures: Congressional Assault on the Best of America."
Priscilla Lin is a Washington-based preservation assistant with Environment Virginia, an affiliate of Environment America. The environmental advocacy organization works "to promote clean air, clean water and preserve natural spaces."
"If passed, the three bills highlighted in this report would have particularly devastating impacts on Shenandoah," Lin said. "The American Lands Act [H.R. 2588] would require the Forest Service and Bureau of Land Management to sell 8 percent of their lands annually until 2016 to the highest bidder."
"The Wilderness and Roadless Release Act [H.R. 1581] and the Wilderness Development Act [H.R. 2834] would allow road building and logging in the most pristine and sensitive areas of Shenandoah National Park," Lin said.
The latter bill's official name is actually the Recreational Fishing and Hunting Heritage and Opportunities Act.
Kyle Bonini is communications director for Michigan Republican Rep. Dan Benishek, the sponsor of the bill.
"The claim that Dr. Benishek's Fishing and Hunting Heritage and Opportunities legislation would allow logging in any national park is factually incorrect," Bonini said. "The bill is a common sense measure to protect the long-standing tradition of hunting and fishing on federal lands, but explicitly does not apply to logging in areas like Shenandoah National Park or any of the national parks in America."
Continue reading "Environmentalists say Shenandoah National Park at risk" »


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Silent Signal: Exploring Biomedical Science
These resources were developed to compliment the award winning Silent Signal project, funding by the Wellcome Trust and Garfield Weston Foundation. They include interactive lesson plans that explore the societal, ethical, and cultural aspects of biomedical science including immunology, infections, genetics,...
Psychology of Attraction - Who do we like and Why?
A workshop plan and resources backed up by notes of related scientific studies that were developed by Cinelive and Professor Viren Swami of Anglia Ruskin University.
These were delivered as part of 'What's the Grey Matter with Gregory?', an immersive arts/science project delivered across the UK in 2015/2016...
Attracting Hormones - What and Who do we like?
A series of resources developed by Cinelive alongside Professor Dave Hornby of the University of Sheffield, Professor Frank Hucklebridge of the University of Westminster and Professor John Wass of Oxford University.
These resources provide the opportunity for a group to explore the history of our...
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text:
Leaders considering resolution for plant contamination
A city in our area is urging a company and environmental workers to clean up a mess.
At Tuesday's Fort Smith Board of Directors meeting elected officials will urge Whirlpool and the Arkansas Department of Environmental Equality to get moving on a toxic waste spill from the shuttered plant on Jenny Lind Road.
Environmentalists said a plume of Trichloroethylene, a degreaser used at the plant, has gone into the groundwater underneath some nearby homes.
Last week, Whirlpool said they are taking responsibility for a toxic chemical spill that contaminated the groundwater underneath several homes just north of the closed plant in Fort Smith.
"I didn't want the community or Whirlpool or the ADEQ to think we were being lax in the effort so I thought that this ordinance would really have some teeth to it," said Fort Smith City Director Andre Good.
The drafted resolution, urges both Whirlpool and ADEQ to do something about the plume.
"I think this resolution just proves to the community that we're not trying to let Whirlpool off the hook and it also proves to Whirlpool that we are here to listen -- now we're here for open debate and conversation among all the entities involved," said Good.
City leaders are calling this an emergency situation and will have this resolution at their regularly scheduled meeting at 6 p.m.


text: Chris Trimper, 30, of West Ocean City, was recently installed as President or "King Lion" of the Ocean City Lions Club. Trimper currently is the quality control coordinator of Trimper's Amusements in downtown Ocean City. Above, Trimper is being congratulated by his grandfather, Granville Trimper. The elder Trimper has been a member of the Ocean City Lions Club for 58 years and served as its president from 1993 to 1994.


text:
One of the things that's so fun about comedy is that feeling that anything can happen. Anything can be said; anything can be done. Surprise and uniqueness are your friends; the mundane is your enemy. Bradley Beck seems to be a man who understands this. The other night at Accidents Will Happen, I watched him co-host (with Sarah Morawczynski, the latest in what is apparently an ever-increasing lineup of co-hosts) what was essentially a stand-up showcase where, throughout the night, he became increasingly drunker, progressively lost layers of clothing until he was shirtless, and rattled off Polish jokes at Sarah's expense while reading tweets from a Twitter fight he'd had on election night with numerous citizens of the states of Indiana and Kentucky.
And it's not just Bradley's hosting that drives this idea. The performers were just as unexpected a mix of stand-ups as one could imagine. We drifted from the storytelling of Brady Dale, to the character-based black metal comedy of Necrosexual, to the more traditional stand-up of the energetic Alex Grubard. The only thing tying the six performers' styles together was their strong talent and a sense of originality.
Of course, the other side to comedy is structure. Don't let me mislead you: Accidents Will Happen is certainly a well-structured show. Bradley Beck is more than competent as a host, regardless of where he is on the spectrum of intoxication. And the show, while at times chaotic, has a sense of cohesion. It takes place in the back room of the Adobe Cafe, a Southwestern-style restaurant & bar. With a small laminate wood-tiled stage (though the comedians all perform on the floor in front of it) facing a square room of tables and wire-framed, vinyl-coated chairs, you may feel like you're watching comedy in a sort of Tex-Mex themed bingo hall. But with the dynamic stage presence of the comedians, clear and professional sound, and a generally supportive audience, you will feel lucky to be there.
After the show, I sat down with a slightly drunk Bradley Beck and started off by asking him what his show was all about:
Bradley Beck: It's a show where we showcase some of my favorite young stand-ups and improvisers and storytellers and sketch groups from Philly. We also get performers from all over the Northeast. We also have a story that will play out over the course of the night—in between the acts—with me and a kind of a rotating team of co-hosts that usually involves me being the fool of some kind for the audience's enjoyment.
Matt Aukamp: How long has the show been running?
BB: It's been about nine months. This is our tenth one.
MA: How do you go about selecting all of your guests and features?
BB: Some of them are just people that I've been watching evolve over the stand-up scene and the storytelling scene for the last two years that I've been doing comedy. But some of the other acts come from [co-hosts] Alex J. Gross and Dan Vetrano. They know a lot of people from the improv and sketch scene so they'll recommend a lot of people and I think, between the three of us, we've been able to get people in the room that have never worked with each other before—so many people from different genres of Philadelphia comedy come together on one stage. It's very different from a lot of other shows.
MA: Is there an over-arching theme of the show?
BB: The over-arching theme of the show is alternative comedy. There's been a backlash in the last couple of years, I've noticed, against alt. comedy. They say that stand-ups should be able to go into any room and these alt. comedy rooms kind of coddle performers, but I put this show up in defiance of that. Like, I wanted these different performers to come together under the banner that we're doing something that's different. We're taking risks. And I want people to get together and it doesn't matter what genre you are, as long as you're doing something different, something new, something that's going to excite the crowd—that's the people that I want.
MA: What sets Accidents Will Happen apart from other shows in the city?
BB: I think that it's a mixed show. I think what sets it apart is that I'm trying to foster connections between the performers, where some of the people that do the show, or even performers that have been on the show before, who maybe aren't performing tonight and are just here, will see some of these different performers – people that they've never met before but live in the same city – and say, "I want to work with this person." That's how it started with Alex J. Gross. I'd never met him before, and I had him on the show, and I absolutely thought he was fantastic and then decided to bring him on as a full-time co-host. If it wasn't for the show, I wouldn't have really gotten to know him.
MA: The second half of the show is an open mic. Do you ever look at that as a place to cultivate talent for your showcase?
BB: Yeah, there's definitely been a few performers that I've booked specifically because I've seen them on the open mic. But also I just really enjoy watching some of the younger guys and girls in their early 20s perform at the open mic. Some of the comedians that are performing tonight have been performing for just a few months and watching them every two weeks here, I've seen them grow as comics. And once I feel confident that they can do at least six minutes of their best material then I'll have them on the main show in front of a bigger crowd.
MA: What are some of the stand-out moments of the show?
BB: The first time I had Necro[sexual] on. He brought up someone to do a Black Metal makeover. The first time I had Lisa Yost on. I'd been watching her perform for two years and I felt like she just put so much emotion into her performance she really threw the crowd for a loop. There's just been so many. I've seen so many performers in Philly put forth a great performance in front of our crowd. These are people that I really love and…I don't get to go out much. I've got two kids at home, and this is the show I would want to see. If I saw these six performers tonight on a bill, I'd say "This would be a great bill." And this way I get to host. It's like watching a comedy show for free.
MA: Any particularly bad moments?
BB: There was this one show I remember where I got really drunk and was shirtless by the end of the show—it was just like ten minutes ago.
MA: What, ultimately, would you like the show to become?
BB: I like the concept of having a story play out in between the acts. We've been doing that for a while. We had one story where we had a Battle of the Sexes. We've had an episode where I was fired and tried to get my job back. Tonight, obviously, we were talking about my Twitter wars and I was getting progressively drunker on stage. I want to give people something in between. I want it to be almost like a behind-the-scenes look at the drama that goes on at comedy shows but brings it to the front.
MA: Anything else you want to talk about?
BB: I just hope people come out. There's a lot of really talented performers in Philadelphia. And I guess I look at this show, ultimately, since it's free, as a way for people that are interested in comedy to sample what is available in Philadelphia. Since I am putting up every different genre of comedy, this is a way for you to come and say, "Oh, this is pretty interesting. Maybe I want to go to some other shows and pay for them. Maybe I want to see these performers at other shows." And it's a way for the performers, since it is a free show and no one's making any money off this, it's a way to put themselves out to people who maybe haven't seen them before. I started the show in South Philly to see if a show could work in an area that was a little off the beaten track. I wanted to bring the show to the young, hip people that live in that neighborhood, and make it a pain in the ass for performers to come down. I wanted them to want to do this show. Since there's no money on either side, I feel it's a way for people that have never seen an indie comedy show to discover the alt. comedy scene in Philly. For the performers it's a place to try new things in front of a really respectful audience. I love when people take a risk on my stage. We try to book a mix of newer acts that are excited just to get booked, and will bring their friends, and more seasoned performers who can use it as kind of an extended open mic to prep for their weekend gigs.
Accidents Will Happen occurs on the 1st Wednesday of every month at 9pm with an open mic at 11pm. South Philly Comedy Jawn, the open-mic-only spinoff of the show (open to any comedic act, with an emphasis on stand-up and storytelling), occurs on the 3rd Wednesday of every month at 10pm. Both shows are held at at the Adobe Cafe (1919 E. Passyunk Avenue). Admission is free!
Matt Aukamp is a writer, performer, and occasional improviser (The Win Show). You can usually find him bothering the world on Twitter at @mattaukamp.


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This is an information website to enable the participating providers of extended warranties for domestic electrical goods to display information about themselves and their services. Please note that this website does not contain details of all extended warranty providers or products. Currys/ PC World, Comet and Argos (the Retailers) agreed with the OFT that they would maintain this website.
You may use this website to search for information in accordance with these terms and conditions. Each extended warranty provider is only responsible for information which it provides about its own warranty services. In the event you have a complaint about information which has been displayed on this website, you should contact the relevant extended warranty provider directly. Nothing in this website shall constitute an offer which is capable of acceptance and nothing in this website is an invitation or inducement to buy any contract of insurance, but if and to the extent any can be construed as such, then the relevant provider has approved it for the purposes of section 21 Financial Services and Markets Act 2000.


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SOMEWHERE, U.S.A. – A few months back we told you about the cross-country bike ride proposed by VCU track and field athlete Tyler Simmons to benefit a paralyzed friend.
On June 1, Simmons, Andrew Kenny and Pawel Loj departed Manassas, Va. and have been chugging across the country for the last six weeks. On July 10, the group blitzed through Utah and into Nevada and are on pace to reach San Francisco on July 17. We plan on hitting up Simmons for a full report when stops pedaling. Whenever that ends up being.
To date, the group has raised more than $18,000 for their cause, which will offset the extensive medical bills of their friend, Ricky Chang. Simmons and Company want to let it be known that they are still taking donations, and that each dollar counts.
If you are still interested in helping, you can find out more at http://www.rickyridesagain.webs.com.


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Hodgdon (HHS) Class of 2012 Alumni List
Help us Update the Hodgdon 2012 Class List by adding any names missing from the list below:
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2012 Class List
Know Hodgdon Class of 2012 graduates that are NOT on this List? Help us Update the 2012 Class List by adding missing names.
Reunions and Hodgdon High School News
More 2012 alumni from Hodgdon HS have posted profiles on Classmates.com®. Click here to register for free at Classmates.com® and view other 2012 alumni.
The students that went to school at the Houlton high school called Hodgdon High School and graduated in '12 are on this page. Register to add your name to the class of 2012 graduates list.
While you are reminiscing about the times you spent in high school at Hodgdon High School, you should also check out alumni photos, yearbook listings and share any reunion info if possible.


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We can also deliver a motivation-themed keynote address at your upcoming conference, off-site meeting or in-service day.


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It may come as no surprise that in trendy Brickell, foodies are getting hip to the latest culinary trend: dark meat chicken.
"I actually like dark meat. White meat dries out if you overcook it," explained Robert Polk.
Grocery stores like Whole Foods Market have noted a spike in demand for dark meat, the chicken's deeper-colored, softer-textured legs and thighs, which fans believe are heavier on flavor.
"It's softer, more fat," said one aficionado, Andrea of Brickell. "Just like a red meat has more fat, just like a rib-eye has more than, say, a chuck steak."
"It's a lot cheaper to purchase, and a lot easier to cook sometimes," added Charles Villard.
Prices for dark meat are rising, according to the U.S. Department of Agriculture. The agency finds dark meat price tags are catching up to the more popular white meat chicken breasts.
In March, the USDA found prices for thighs rising about 15 percent, and 26 percent for drumsticks. The price for both is hovering around a $1.30 per pound.
Despite the extra cost, chicken fans said they are willing to pay a little more.
"You can't give up the drumstick for anything, I'm sorry, that's something you fight for sometimes," Villard said.


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This post was originally written on BARF for the 2008 Cal24. (original thread here). I've tried to edit out the non-bike-specific comments in this post, but if parts of it now don't make sense, the original thread will fill in the blanks.
It's a 2005 R1200RT. I picked it up new as a leftover in 2006. It has just about every option BMW offered at the time, save for heated seats. While the bike would be reasonably comfortable and likely competitive in the rally right off of the showroom floor, what fun would that be. So I've added a few gadgets and farkles along the way to make it just a little more capable.
From a comfort standpoint, I've got a Rick Mayer seat, which is truly all-day and all-night comfortable, compared to the stock seat that can't claim as much. The bike has a Gerbing heated clothing controller installed on the dash, with the pigtail for my heated jacket liner coming out right at the front of the seat. I can dial up anything from a little extra heat to nuclear. Between the Gerbing and the heated grips, cold simply isn't an issue. I've installed a Cee Bailey windscreen, which is significantly taller and wider than the stock BMW screen. The screen is electrically adjustable, so when it is in the all the way down position I can easily see over it, and am never looking through it in the twisty bits.
But when the road straightens out and I want some peace and quiet, or at least zero wind noise, I can move it up on the fly:
There are a few gadgets on the handlebars. From the left I have a Valentine One radar detector, a Garmin 60Cx GPS, the iPod Nano, and finally another Garmin GPS, the Zumo. The V1 needs no explanation, but the reason I have two GPS's may. Initially I had meant to replace the older 60Cx with the Zumo, but it turns out that the Cx has some very useful features that were left out of the newer gadget, so I just kept it on the bike. Also, having 2 GPS's on the dash allows me to aim them at different points during the rally. I typically have one always aimed at the next checkpoint, and the other at whatever bonus location I am currently searching for. This lets me know how I'm doing on time compared to the checkpoints, so I always know when it's time to drop everything and head straight for the barn. All of the audio from these gadgets is wired to an Autocom unit installed under the seat, so a single wire coming from there to my helmet allows me to hear all of them at once. The Autocom prioritizes the devices, so for example everything else is immediately muted the second the radar detector sounds an alert. The Zumo connects to my cell phone via Bluetooth, and allows me to make and receive calls on the fly; the audio is piped right through the Autocom to my helmet speakers/microphone. The clarity is surprisingly good, it's easy to hold conversations at speeds much faster than it may be recommended to have conversations at.
From a performance standpoint, I've swapped out the BMW's ESA shocks, which had worn out by 15k miles, and replaced them with Ohlins front and rear. The spring rate is set up for a larger than average bear, who likes to ride faster than average on twistier than average roads. It remains a smooth highway cruiser, but it is also surprisingly capable when the going gets twisty. I've run quite a few different types of tires on this bike, and my favorite, by far, are the Michelin Pilot Road 2's. The RT has a 7.1 gallon fuel capacity, and rarely gets less than 38 mpg. I usually fill up between 200 & 250 miles on a tank, but if I'm in fuel-saving mode I've gotten over 315 miles at a single stretch (on the 2007 Cal24, in fact, the leg before the checkpoint in Lone Pine). The trip computer has a miles-to-empty feature, which comes in quite handy. When it hits zero miles, which it likely will at least once during the rally, there are still 20 miles or so of gas left. Lighting is pretty important on these 24-hr rallies, so I've made some pretty substantial upgrades. Each of the 3 H7 bulbs has been swapped out with Ultrastars, which gave a nice bump in brightness and distance. I also installed two Touratech auxiliary lights; one HID on the left and one fog on the right. The HID is absurdly bright, while the fog is actually more useful for folks to see me rather than lighting up the road.
From a safety and reliability standpoint, I've added Hyperlites to the back of the bike to augment the standard brake light, these are two banks of LED's next to the license plate that flash continually when the brake light is engaged. When the 3 bags are installed on the bike, I feel that the stock light isn't as visible as I'd like, and these help. In the glove box on the top right of the fairing, I've stashed a maglight (there will be several flashlights in different places on the bike), a reasonable set of tools for minor roadside fixes, a tire plug kit, and an electric air compressor that plugs into the BMW's auxiliary power sockets.
I've saved one of the neatest gadgets for last, the SPoT Satellite Messenger. This is a small hand-held device that communicates with the Globalstar satphone network to report position, and a few different types of alerts. It sits right inside the top of my tankbag. I will have it configured during the rally to send up my position every 10 minutes, so people here can track the bike throughout the day.
But just in case all of the electronics get hit with a solar flare, I can always rely on some human assistance stashed in the topcase. Remind me to poke some holes in the plastic...
I've posted all of these pictures (in full 10 mp resolution) , as well as a short video, up at this smugmug gallery. Here's a video of it as well:


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Love is blind. And sometimes dumb. It's great that Broncomaniacs love their team. But being upset that there's a banner of Baltimore quarterback Joe Flacco on Sports Authority Field to promote the NFL season-opener?
Well, that makes us look like a dusty old cowtown. What's next? Throwing a brick at Howard Cosell when he appears on TV? Oh, wait. That already happened. Guess we haven't matured much as a major-league city.
Listen to me, Oren Lomena, Peter Burns and the Press Box crew discuss "bannergate" here:
Oh, we get why Bronco fans are irked. Many in Denver still have nightmares about Flacco's 70-yard TD pass in the playoffs. Me? I'm more upset with Rahmim Moore.
Kick it with Kiz and Peter Burns by joining the discussion on Mile High Sports Radio Monday through Friday from 7-9 a.m. on The Press Box at The Denver Post or at 93.7 FM and 1510 AM on Mile High Sports Radio.
Find Kiz on Twitter @MarkKiszla. And Peter Burns @PeterBurnsRadio.


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We are in the midst of a very exciting and important presidential election, so I thought that we could spend some time discussing what we think should be done about healthcare. In particular let's discuss what we think is wrong with the current healthcare system and what kind of things we think could be done to fix it. Below is a quick summary of the candidate's healthcare plans (based on a summary from the New York Times).
Clinton's plan - Require everyone to get health insurance, subsidized by employers and the government; pay for it by rolling back tax cuts for households earning over $250,000 and savings in the existing system.
• Requires large employers to provide insurance or contribute to the cost.
• Provide tax credits to small businesses and subsidies for low-income people.
• Create a pool of private plans similar to the program for federal workers and one public plan similar to Medicare.
• Make plans portable from job to job.
• Expand Medicaid, State Children's Health Insurance Program.
McCain's plan - For free-market, consumer-based system; has pledged affordable healthcare for every American without a mandate; says universal healthcare is possible without a tax increase.
• Sees controlling health costs as a top priority.
• Make plans portable from job to job and accessible across state lines.
• Provide $2,500 tax credits ($5,000 for families).
• Revise tax code to "eliminate the bias toward employer-sponsored health insurance."
• Move to compensate medical providers based on the quality of their work.
• Bring greater competition to drug markets by safe reimportation of drugs and streamlining the process for introducing generic drugs.
Obama's plan - Require that all children have health insurance; pay for it by rolling back President Bush's tax cuts for households earning over $250,000; aims for universal coverage.
• Requires employers to provide insurance or contribute to the cost.
• Exempt smallest businesses.
• Reimburse employers for catastrophic health costs.
• Provide subsidies for low-income people.
• Create purchasing pool with choice of competing private plans and one public plan like Medicare.
• Make plans portable from job to job.
• Expand Medicaid, State Children's Health Insurance Program.
When I lived in Europe, I was introduced to the social healthcare system in Holland and in France. It was basically the same as over here, except that the cost to visit a doctor, even a specialist, was very cheap. The most that I ever paid for a doctor visit was 50.00 euros and this was a heart specialist who did an EKG and an ultrasound in the office. I had to pay the cost up front because I was covered under a private insurance and my insurance company would refund the money. But still, I thought that it was cheap enough that I could afford it even if they were not refunding me.
If you were covered by the social healthcare system, you had a special card that looked like a credit card and they would use that card as the method of payment. If I recall correctly I don't think that they had to put money on the card, I think everyone got a certain amount. And, in Holland, they kept track of all your healthcare records electronically. They had a government database that all the doctors and pharmacists were plugged into and everyone knew the same medical information for you. There was no repeating your information to each doctor a thousand times because it was all in the database. I found it very nice and a very high tech system. France was not so sophisticated, they did not have a huge database but each doctor wrote a letter to your general practitioner explaining exactly what he or she did during the visit and what your symptoms were. This allowed my general practitioner to always know what was going on with me because he was in the loop.
The big problem with the social system is that the taxes were very high and sometimes there could be a long wait for a procedure. This was obvious to me more in Holland than in France. In Holland, they would often tell me that I could not get the procedure done for six months or so, but they would usually call within a month with a cancellation. For some reason, for me, I didn't encounter any problems with wait in France. But in France, I went to a private hospital for the fistula complications rather than the main hospital (where I went for my Crohn's appointments and Humira shots). It was much easier to have a procedure done at a private hospital (clinic) rather than the hospital.
I think that the cost of seeing a doctor here in the states is surprisingly high and if you don't have health insurance, I am not sure how someone with a chronic disease can afford it. I guess you could go to the emergency care or if they have some sort of out patient service. Maybe someone can provide more insight? I think that the cost for a doctor visit is high because all the doctors have to pay such high fees for the malpractice insurance and lawsuit protection.
One other problem that is very noticeable is that the insurance companies seem to dictate our medical treatment. The doctor prescribes me a medication and the insurance company says that they will not pay for that medicine that I have to take this other medicine that is not as good. Who are they to decide?! The doctor is the one with the medical degree and is the one who knows my situation and for reasons which the health insurance company may not know, he prescribed me that specific drug – not the one that they want to pay for. It is all about money and it should be about health.
I don't know what the solution is or what it should be, but I think that it would be an interesting topic of discussion. I am interested in hearing your opinions.
Take care,


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Mayor-elect Martin J. Walsh is shooting down the plan to arm some Boston patrol officers with military-style rifles — setting up a potential showdown with the department which has backed the controversial measure, citing a need for high-powered weapons in light of school shootings and the marathon bombings.
"Mayor-elect Walsh is opposed to the AR-15 rifles," his spokeswoman Kathryn Norton said in a short statement yesterday. "Unless otherwise convinced by the Boston Police Department, he does not think they are necessary."
Walsh would have to approve a budget for 33 AR-15 rifles at a cost of $2,500 each. Police were in the planning phases of acquiring the rifles to put in the cruisers of two specially trained beat cops in each of the city's 11 districts.
Boston police spokesman Sgt. Mike McCarthy had said the plan to buy the guns and arm officers was in the works before the marathon bombings and was motivated by a nationwide surge in massacres such as the Sandy Hook Elementary School shooting in Newtown, Conn., when suspects are still armed and shooting. The use of the weapons, he said, would be strictly regulated and would not be used during routine patrol. Use of the weapons could include an active-shooter incident, firing on a suspect from a distance and confronting a suspect wearing body armor.
Source: Police One


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We would love to welcome you in to our newest restaurant, Jin Sho!
Join us for Executive-Class Japanese Cuisine on California Avenue in the heart of Palo Alto!
- Omakase sushi 8pc
Enjoy chef choice 8pc best sushi of the day
- Monday-Friday
- Lunch: 11:45am-2pm
Dinner: 5:30pm-9:30pm
- Friday
- Lunch: 11:45am-2pm
Dinner: 5:30pm-9:45pm
- Saturday
- Dinner: 5:30pm-9:30pm
454 S. California Ave Palo Alto, CA 94306


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See also: Beckwood Press Company
Related Enterprise Zones: Presses


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DOVER — Police continue to investigate two separate acts of indecent exposure involving two school children earlier in the month.
Lt. Detective Brant Dolleman said police are interested in any information the public may have regarding to the acts which occurred Wednesday Sept. 5 and Thursday Sept. 6. To date, no arrests have been made.
According to police, on Sept. 5 between 8 and 8:15 a.m., a Woodman Park School student was approached by a man while waiting for the bus on Bellamy Road. She described the man as wearing no clothes from the waist down and stated the suspect was a cleanly-shaven white male with short brown hair driving a silver or tan four-door vehicle.
The second instance occurred Thursday afternoon between 2:20 and 3 p.m. when a middle school student reported being approached by a man while she was walking home from school on Alumni Drive. She reported the man offered her a ride home and was also naked from the waist down. That suspect is described as a white male with black hair and a goatee wearing a red shirt and driving a black car.
Both cases are being investigated by the Dover Police Department's Special Investigations Bureau and a letter was sent home to parents throughout the district alerting them to the incidents, which Dolleman previously told Foster's are very concerning.
On Monday he said leads are being followed and information being provided is helpful.
"We've gotten a lot of tips and appreciate the information the public has provided," Dolleman said.
Anyone who may have information regarding the acts of indecent exposure is asked to contact the Dover Police Department at 742-4646. Those wishing to remain anonymous can call the Dover Crimeline at 749-6000 or go to dovernhcrimeline.org on the Internet.
Police still seeking leads on indecent exposure incidents
DOVER — Police continue to investigate two separate acts of indecent exposure involving two school children earlier in the month.


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OKLAHOMA – It's almost time to say good-bye to 2016, and hello 2017!
People everywhere will be ringing in the New Year this weekend, but there are other events families can check out.
There is still time to see "Elf The Musical" at the Civic Center tonight and tomorrow.
Families can follow Buddy the Elf on his adventure from the North Pole to the Big Apple.
Click here to buy tickets online or you can buy them at the Civic Center.
If you'd rather be outdoors to kick off the new year, join the "First Day Hike" at Lake Thunderbird State Park on January 1, 2017.
The staff will lead the 2 mile hike at 1 p.m. starting at the Nature Center on Alameda Drive.
Hot chocolate and snacks will be offered after the walk.
You can watch Discover Oklahoma on NewsChannel 4 at 6:30 p.m.


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Tournament SignupJanuary 2012February 2012March 2012April 2012May 2012June 2012July 2012August 2012September 2012October 2012November 2012December 2012SeriesPoolsQuick LinksMembershipsAffiliate ClubsOffice Use Only
IDGC - Appling, GA
Tournament Director: Jason Allind
Email: jall...@pdga.com (click the dots to reveal)
Phone: (706)261-6342
Tournament website: www.discgolfseries.com
Quick LinkTM: Players / Results
Online registration preferred. Registration day of starts at 9am.
8/1/08 3:00pm EST Note: Online registration for this event has closed.
Choose your desired division:
"I hereby hold blameless and fully release the Professional Disc Golf Association (PDGA), the tournament directors, local and state park services, and all tournament partners/sponsorsand individuals or parties associated with the IDGC Monthly Series, from all liability of personal damage or injury which I may incur before, during or after my participation in this event. I accept fulland sole responsibility for any damage I may cause through negligence and/or malice, including damages orinjuries caused by my own throws in practice or competition, as well as damage occuring at any of thevenues where event activities are conducted.
I also recognize that the PDGA, event staff, and any other media outlets covering the event have the right and responsibility to record any participants via video and still photography.Such photography may be used for event publicity, public information or any other promotional use that falls within PDGA or event activities."
Note - A Parent or Guardian must sign if player is under 18 years of age.
Entries must be received by FRI 8/1/08 3pm EST.
A $3.00 handling fee will be charged on this registration.
Charges will show up on your credit card as "FRISBEES8885969347".


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Export 337 results:Author [ Title] Type Year
Filters: Author is Peter H.N. de With [Clear All Filters]
"ViCoMo: visual context modeling for scene understanding in video surveillance", in SPIE Journal of Electronic Imaging, 2013, pp. 041117-1 - 041117-19.,
"A Video Display Processing Platform or Future TV Concepts", in IEEE Transactions on Consumer Electronics, 1999, pp. 1230-1241.,
"A Video Display Processing Platform or Future TV Concepts", in International Conference on Consumer Electronics, 1999, pp. 208-209. (175.9 KB),
"Video-Based Fall Detection in the Home Using Principal Component Analysis", in Advanced Concepts for Intelligent Vision Systems, 2008, pp. 298-309.,
"Video-Object Segmentation using Multi-Sprite Background Subtraction", in IEEE International Conference on Multimedia and Expo (ICME), 2004, pp. 343-346.,
"View Interpolation Along a Chain of Weakly Calibrated Cameras", in IEEE Workshop on Content Generation and Coding for 3D-Television, 2006.,
"Virtual-view adaptation for 3D multiview video streaming", in IST / SPIE Electronic Imaging, 2010, p. 12 pages.,
"A vision-based approach for tramway rail extraction". 2015. (8.14 MB),
"Water Region and Multiple Ship Detection for Port Surveillance", in Proc. the 33rd WIC Symposium on Information Theory in the Benelux, 2012, pp. 20-27.,
"Water Region Detection Supporting Ship Identification in Port Surveillance (ACIVS)", in Advanced Concepts for Intelligent Vision Systems, 2012, pp. 444-454.,
"Water Region Extraction in Thermal and RGB Sequences Using Spatiotemporally-Oriented Energy Features", in IS&T Electronic Imaging - Algorithms and Systems, 2017. (9.89 MB),
"WIC Midwinter meeting on IP-Television (IPTV)", in Proceedings of a Workshop organized by Werkgemeenschap voor Informatie en Communicatietheorie and IEEE Benelux Chapters on Consumer Electronics and Information Theory, 2007, pp. 1-110.,


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I'm working on a review essay that covers the various academic podcasts about religion and religious studies that have appeared in the past few years. I'm limiting myself to academic podcasts, or at least podcasts that feature academics. So, I'm not including things like Interfaith Voices or On Being. I am interested in podcasts not necessarily in religious studies but that have scholars discussing religion, such as the Junto Podcasts. Here's a list of what I have so far.
What am I missing?
Let me know in the comments or on Twitter/Facebook/Morse code/carrier pigeon/YO.
Journal of Southern Religion http://jsr.fsu.edu/new-media/
Directions in the Study of Religion- Marginalia http://marginalia.lareviewofbooks.org/category/interviews/
First Impressions- Marginalia http://marginalia.lareviewofbooks.org/category/interviews/
Religious Studies Project http://www.religiousstudiesproject.com/podcast/
New Books Network http://newbooksnetwork.com/
McGill http://podcasts.mcgill.ca/tags/religious-studies/
Oxford http://podcasts.ox.ac.uk/keywords/religion
Research on Religion http://www.researchonreligion.org/
Center for the Study of Religion and Conflict https://itunes.apple.com/itunes-u/religion-and-conflict/id383721017?mt=10#ls=1
The World of Islam: Culture, Religion, and Politics http://aminetais.podbean.com/
The Junto Podcast Network: http://earlyamericanists.com/the-junto-podcast-network/


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Continued from the first thread. Hope not one minds if I start this new one up.
There's reception this Saturday in the Eagle, Idaho area (just west of Boise) and one at the end of March in Kirkland, Washington (across the lake from Seattle). I don't know if either of these are convenient, but I'd love to meet any of you in person
If you wanted them to be convenient, you're not only putting them in the wrong country, you're on the wrong side of the wrong country. Frankly I think is a deliberate attempt to exclude me. :P
I must say, Tach is quite a handsome fellow. Did you make that image, Gibson8088?
Thank you, Dawn. Actually, I cheated in a sense to make the image. I used the character creator that comes with Eve Online to make it and took screenshots during the process. They are generous enough to let you sign up for a free trial without having to buy anything.
IJ and Gibson. Great stuff you guys have got going on, very dramatic.
That said, I would like the point out: Tey Spires and Kenlan As Buka, the only single men in Tapestry, not to hit on Fiola. Future writers of Tapestry, endeavor to have your name put on this illustrious list!
What fun would being on such a list be? Heck, I propose my own list!
Women who have been hit on by Tach! The first is the lucky lady Fiola! Congratulations!
And thank you for the compliment, Ice! It's so nice to be writing with somebody again... reminds me of the early days!
Hey, great post, Gibson!
Thank you! A completely random bit of humor I decided to toss in for fun.
Why do I get this feeling Tach is going to end up getting wrapped up in more trouble?
Trouble? A kidnapping isn't trouble. It's Tuesday. You're only reaaalllly in trouble when Imperial cruisers hunt you down, or slavers catch you shop-lifting, or if the building you're in explodes, or if you meet someone with a card playing ferbil.


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If you go can you let us all know how good it is??
Nottingham viking stuff
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Re: Nottingham viking stuff
Its a touring one that is gong round the country. Some bits from the museum and other bits being asked to lend from re-enactors so the real exhibits will be interesting.
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