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Kids' stuff, perhaps, but Robert Louis Stevenson's bit about the world being full of a number of things and how we could all be as happy as kings leaps to mind. Those lines had resonance for me! Just out of Columbia as the 1950's commenced, and equipped with a Master's Degree, how could I doubt the poet? I read, read, read in preparation for my calling, a pursuit I imagined as my route to happiness. So I charged into post-war New York City's publishing industry, the hub of its world.
I pictured it waiting, that one position for me alone — someone whose eyes had been fixed upon a life at its center. And I dreamed of the marvels I could introduce: Who else could turn up the best young talent, spot the emerging thinkers and hear the poets of our generation — those aspiring Joyces, and young Dylan Thomases? I'd pick up Europeans not yet translated into English along the way. It was my special version of a missionary vocation. Only I wouldn't depend on charity — I'd have to earn my keep.
Perfecting these skills, I'd seek inspiration to become more discerning while learning spectacular things every day of the week. I saw it as the high road to the romance of literature. A profession to command a panorama of all times and places!
I got busy, scouring Manhattan. Month after month, I chased about, answering newspaper ads, writing letters to editors to tout my abilities and traipsing into the offices of publishing houses. Finally, under the supervision of those few "elite" agencies that offered such job listings, I went to interviews to find that crack in the wall, the ideal match for me, a perfect publisher to show my stuff off to.
I exhausted every institution in the business, slogging my way back and forth along those streets in the 40's through 60's, on Fifth, Madison or Park, until I knew every crevice of the pavement, every lunch joint in the vicinity. I worked my way through skyscraper buildings, posh lobbies and doormen, from one company to the next.
What fantasy my notions proved! When I did manage to get a proper interview and attended those who had sought my help, it was only to be disillusioned. Demands were enough to dismay any novice: "Can you type?" "Can you take shorthand?" were regularly shot at me. What followed was the news that pay would be scant. So many beginners, they casually tossed out, sought such posts, they could find eager workers merely for the love of it. These spots, they referred to as their "internships," an innovation for graduates of Vassar, Smith or Radcliffe, and other colleges for children of the rich.
Such starter positions had been smartly designated by employment agencies as "Assistant to Editor," though their hunt was actually for a "Secretary," in a practice providing these straitened publishing houses help cheaply. Elaborate promises accompanied their offers: for exposure to educated company and an intellectual atmosphere, new and ingenious ways of thinking. Even in distant recollection, I can hardly bear to contemplate the disenchantment all this brought me. Abject naiveté, as it manifests itself in youthful inexperience, has long since perished from my memory.
I came to see no "breaking into" that business along that route. At least, not for the impatient, impoverished like of me. I was no Vassar Girl, newly-arrived in the metropolis for the purpose of imbibing "culture" or " city polish" before marrying. Nor was I "apprentice" material, I was in too much of a hurry. Moreover, I'd been taught by my struggling immigrant folk, that an honest day's work came rewarded, if modestly at first. All that education, as my Dad sneered, didn't come free! Nor should efforts that resulted from it.
What became plain as I struggled through those Manhattan offices was that at best, one could go on for years performing menial chores, typing letters and fetching coffee, yet hardly experiencing the pleasure of uncovering young talent. An overworked superior might deign to delegate a manuscript for reading over a weekend, only to find out what "the kid thought," and whether it might be dumped outright or required her own time.
However, such assignments came straight from the "slush pile" publishers stocked by the cartload. These were still the times before literary agents had conquered total control of the business. There was also the off chance that office politics could allow some lucky new world change, a promotion of a superior, elevating her assistant to greater prestige in the company, yet the change would not alter those daunting routines before her daily.
The realization left me not only jobless but despondent too. At least, until I came upon a different course, an occupation that could pay its way while still engaging the head. The idea arrived one day, in the form of a fortunate recollection from my undergraduate days at the University of Chicago. There, any number of graduate student friends, themselves desperate for employment, had found their own solutions. Smack on Chicago's campus was the American seat of the vastly successful Encyclopedia Britannica, to which they could offer their research skills. Why not, thought I, seek an equivalent here in New York City? There must clearly be such.
I remembered too that as a child my own mother had, one morning years before, answered our doorbell to find standing in the hallway an upstanding fellow, well-dressed, young and selling some product. During those difficult economic times, it was not uncommon. Had she herself not succumbed to such a purchase when that salesman explained to her that he represented the BOOK OF KNOWLEDGE? A work, he had claimed, whose aim was "to transport her children to a new world."
Elegant talk, and such a convincing spiel, he managed to clinch the deal. In that Depression era, books of any kind were hardly a priority item, and my Mom was a tough customer. Still, these books appealed, seemed special enough to her to lead us on a path to discovery, to new thoughts, another way of life. And, she chirped, "how deluxe" the edition would look in her living room!
So it wasn't long after that we kids discovered a series of huge volumes, some twenty of them, delivered in box after box. Each of them leather-bound, printed on fine vellum paper. Indeed, they were to become the road to another kingdom. Just to read tales of past glories right under our own roof was inspiration.
Why not, raced my thoughts in my job-hunting frenzy, seek out that company? The same which had sold us? Could there be any doubt that they thrived, or that they were here in central Manhattan? So I turned my attention in a new direction, to market what I termed "my research skills," a dubious notion, since graduate school work for a Master of Arts degree taught little enough about how to find information, or categorize it.
The curious fact was that once I'd found this path, I had rid myself of the curse haunting me. Those wretched demands for secretarial skills which had soured every potential now went unmentioned. The Grolier Society, parent company for The Book of Knowledge as well as the Encyclopedia Americana, was to prove a venerable institution still intact and situated comfortably in an old emporium just off Fifth Avenue on 45th Street, a street I had slogged across often enough during that long hot job-hunting summer. And after a mere explorative phone call, I was directed to come in "to visit."
It was already into late August by then, and oddly enough that worked in my favor. I had discovered when ringing the company's line that the hiring staff was off on its yearly holiday, and that none were available for weeks to come. Yet, the gentleman who had picked up did not interrupt me as I made my little pitch and even seemed interested (or perhaps, it was merely his own boredom with the quiet currently in his office). He then agreed to meet and interview me for that first appointment. I soon learned that he was none other than the Editor-in-Chief of their Research Department.
If a touch abstracted and casual, he proved charming. A scholarly fellow, dressed in proper summer linen and Ivy League necktie, which seemed appropriate to his upper-class Boston speech. His chat was worlds apart from the newspaper ad and agency world I'd been trekking through in these last months. The moment was such as one seldom encountered in the course of job hunting.
I spent almost a full hour with the cordial gentleman, who appeared happy for company on such a dull summer day. We conversed rather than interviewed, about literature generally, and later on he discoursed about the true nature of research. His casual, "Indeed, we are always seeking to find those educated broadly in the humanities for our staff," heartened me. Yet nothing of any specific need was so much as touched upon.
So did he proceed, explaining that as publishers of the BOOK OF KNOWLEDGE and the ENCYCLOPEDIA AMERICANA, they employed the finest scholars of our own nation and England's as well. And, that there still were other responsibilities which his own department must carry. With the purchase of each set, readers were presented with a series of coupons. These, he continued, could assure buyers that if solid material within Grolier encyclopedia were not easily available — about historic or contemporary figures — or any other subjects, such answers would be forthcoming. They could submit one of these coupons with the demand that The Grolier Society staff promptly research a thorough report in answer to such missing links. These materials were guaranteed delivery to subscribers within a short period, 10 days or less, via the US Post Office.
He concluded, "This is what we here at the Research Division occupy ourselves with. Our need therefore, for informed, and organized young scholars remains constant."
Encouraged, I was enabled to mention my own exposure during my years at the University of Chicago to some of the best minds in the Academy. I spoke of those professors whose very aim was to organize young minds with emphasis upon tying together human achievement in all of history for future example.
And, if this gentleman ended our fine hour on an uncertain note regarding an immediate opening, I left him that day satisfied that he could turn everything in my favor there. For once, I had made an impression.
But what I learned too was something more. It made me see the futility in my earlier hunt, that the book publishing industry was not the way. For one so impatient to do her own thinking, it could lead only to frustration. Research, on the other hand, demanded ingenuity, provided a chance to hone my thoughts, work at my own writing skills to make them serve the needs of readers.
I persisted in a few half-hearted investigations of publishing houses after that momentous interview, and kept up with the employment agencies, but to no avail. And, not a month went by before I was indeed called upon by a member of the abstract gentleman's staff to return to the Grolier office, where I managed to snag a job. My first position, exaltedly titled, Research Editor. And the salary, though still low for that period, was a couple of dollars above any I'd yet been offered at a publishing house.
Even my Dad had little complaint. His silence was tolerance at least. It made living at home possible, which in those days was something of a requirement for those unmarried. In sum, he muttered out to my Mom a meager compliment, "At least she can pay her subway fare and lunches now."
Yet I saw it as liberation, a different standing, one that counted. When I told of it, it smacked of someone on her way. Not perhaps to my parents, but to more knowledgeable friends. And I launched into my new assignment with energy and excitement. An eagerness evident to a staff at my new office who themselves had already settled into their routines and grown blasé.
Oddly, learning from these office mates turned out an education in itself, arriving in novel form. For me, it was the people themselves, their intellectual inclinations, their sophisticated speech, their crisp wit in delivery which touched every aspect of my days and later still, my evenings as well. They themselves attracted, fascinated even more than the daily grind of the research. I had hardly met an assembly of such varied sorts in my Bronx world before. Among them were not just New Yorkers but some who'd come from other sections of our vast country. Several already lived Bohemian lives in trendy Greenwich Village. They knew a city that I had had no real hint of, had not yet encountered.
First of the group to claim such attention was my immediate superior, the editor assigned to oversee my research. He was a tall blonde young man, about twenty-five or six, handsome, soft-spoken, his native tones from some upstate New York "hick" town, and one which he wryly explained was a place, "I could not escape from fast enough!" I was instantly awed by his sophisticated manner. Nor was I alone in such admiration, apparently. Just about every young female in that office was mooning over his dreamy blue eyes, and thought themselves more than a bit in love with him.
Such was his casual flirtatiousness, it proved tough enough to resist. Naturally there was that inevitable studio apartment right "down on 10th Street" to which he was soon to offer invitations of various sorts, among them "to listen to his classical music on his collection of "long-playing" records, then much coveted and only just coming in. It was he, in fact, who first introduced me to such works as Schubert's Die Schöne Müllerin, Stravinsky's Symphony of Psalms and to the still little-known Mahler wonders. He could even discourse seductively upon the latest classical performers emerging during that period, the like of Glenn Gould or Vladimir Horowitz, for instance. How might anyone not fall for such a marvel?
There was, among that group as well, our Mid-Western contingent, young women whose own knowledge of the City I had grown up in staggered me. They knew secreted lairs everywhere: those special libraries and archives, haunts for scholars of each period and variety. This surprised me. You could hardly anticipate such expertise coming from attractive young girls, who were least of all inclined to interest themselves in these remote matters. During their off moments, and often enough, they stood together in the office clacking about their hair-styles or make-up, gossiping about their boyfriends.
There was one lovely sophisticate in that office from the distant West Coast. She had taken to New York City as thoroughly as any native. She knew her way about alright! Such a savoir faire in that olive-skinned face, those black-eyes, so smooth she could stare you down with a mere glance. About her was an oddly watchful, even suspicious manner. In every conversation or event, she seemed to to glance over her shoulder, listening for a whisper behind her back. Yet, what puzzled most was how she combined such ill-ease with worldliness. At least, until I learned of her circumstances.
This occurred one evening at an unexpected meeting in The Museum of Natural History, where we had met by chance. She escorted a child, a black boy of ten, newly-come from Los Angeles for a visit, and whom she presented as her visiting nephew. I was stunned to learn then of her true origins. She came of a Black family in Los Angeles; yet having removed herself from home,, she'd crossed the country to begin again in New York as she offhandedly boasted, to "pass for white."
Since we were safely distant from our office environment, had met entirely by accident, she made that introduction casually enough, if in a somewhat subdued manner. With no one else in sight, she laughingly confessed to what had now become evident. Moreover, within minutes she managed to communicate that she planned to keep it that way. The circumstance was not to be mentioned in office circles! Nor did I, ever.
Those days were full of dramatic disclosures. They varied, but each had its poignance, tales of life's vicissitudes, all revelations for a shielded Bronx girl just now moving toward independence. Indeed, I came to comprehend Hamlet's cautionary remark to Horatio that there are more things in "heaven and earth" than I'd ever dreamt in my philosophy! Those disclosures were nothing like the childish or adolescent discoveries I'd once made.
And in the course of my years at Grolier, I saw much, much more of the world, distressing to me from time to time. There were diverse, alternate and even deviate relationships possible. They were all around us, the sexual ones, for example, of the very sort that had always remained unmentionable among my parents and relatives. They poured out before me to make evident my own well-protected middle-class Bronx childhood.
Still other discoveries came at me fast in learning how to do the job. To seek, to find, to see, in short, to acquire successful ways to dig for information. To learn, and learn quickly was the aim. While I trained at the Grolier's Research Section, they undertook to initiate these skills. What with the plethora of special libraries buried in the City's bowels, one could manage to unearth obscure materials, from ancient or medieval history, from histories of art, or pursue exacting theories of the sciences and engineering. Uniquely, one studied the means to do so with efficiency and speed. That was the greater challenge at Grolier.
My very first assignment chosen for such training is memorable. A subscriber had complained to the Encyclopedia staff that though he had scoured their volumes, he'd not found his key question answered. He submitted his "coupon" to demand his need be answered. His request read: "HOW CAN I MOVE MY HOUSE FROM ONE LOCATION TO ANOTHER PLACE ACROSS THE CITY?" Moreover, he made himself quite plain: he required specifics, not just the sort of thing he had already found in the book: "get a truck and loader," etc. He planned to execute the entire process by his own labor, with the assistance of his son; hence his need for "specifics."
My chore was clear. I must find instructions, procedures, a blueprint for this layman, that he might accomplish his momentous task without mishap. Awesome! And the most terrifying part for me was the deadline to manage such a complete operational plan inside a week.
Those first moments of despair finally passed. I was dispatched to the section of Grolier Society's own extensive library and advised on where to look. When that research was completed with the discovery of several books on planning for the execution of a house move, I was next advised to locate and call upon some construction engineers for further instruction, and, finally to telephone our own City consultants to hear further particulars about local law for house moving, those safety regulations governing such movement through New York City streets. I was able, astonishingly, to present for my senior editor some semblance of a workable program.
There were scores of such "off the wall" assignments. Indeed, they came at a pace. Take the one that read, "What is Natural Childbirth? Why should I consider it?" That had me scouring the 42nd Street Public Library, whizzing through volume after volume and on to Grantly Dick-Read, the then most recent researcher on this subject, and, in the end, learning far more than I'd ever dreamed about giving birth to a child! And, following right along, came scores of assignments which demanded particulars about career possibilities. Endless requests for summaries of "Architecture as a Career," or "Foreign Trade as a Career," and any number of variations on that theme.
Yet all this was mere prep. I was quickly allowed to move away from such miscellany, to get on to my supposed area of specialization, queries pertaining to the arts. I can recall as well, the earliest of these to come my way. Someone, way out in mid-America, had recently heard of musicians and singers termed "troubadours." She'd learned from her high school teacher that back in the Middle Ages fine ladies had been regaled by them with song. The idea so enticed her, she must find out more. Could her coupon claim a thorough investigation of such remote musical practices in those early centuries?
The young lady yearned to know its sounds of both voices and instruments, to discover in what circumstances songs might have been heard, and by whom? What were the instruments, she wondered, with which this music was played? Her inquiry concluded with a sweet lament about how few might have enjoyed such privileges, while she, at 15 years of age could listen to her "long-playing magic every single day of the week."
Dispatched to The Cloisters at the northern tip of Manhattan, I was soon to investigate her theme in all its variety as it passed through the centuries in which such practices prospered (12th to 14th), all the while delighting in the study of intricacies in courtship, chivalry and courtly love. Such, indeed, were the pleasures of this, my first job in the real world! Of course, I'd visited at The Cloisters before, wandering the City in my adolescent days. But when, I appeared now as a representative of the staff of the Encylopedia Americana, I merited special attention. Cloister librarians were attentive, happy to help. Their satisfaction came in being able to produce the proper works for my rapid research. Then too, there came a bonus: they offered techniques new to me for handling precious books, the aged editions held in their Medieval collection. Their strictures regarding the need for delicacy in examining these ancient tomes has ruled me in libraries ever since.
I rushed as well to the Music Library, then still at 58th Street (and not yet re-designated The Performing Arts Library, to be centered at the later-built Lincoln Center), another venerable institution in the City, there to seek more particulars about unique musical instruments of the period. The miracle was that I managed against the odds to write up a cogent treatise for our eager young subscriber by the week's end.
There were countless demands by coupon senders for strictly historical pieces. These were frowned upon by our dedicated staff editors. We all were aware that such information was amply provided within our volumes, whether they be within the juvenile encyclopedia or those for adults. Had such readers consulted them, they would easily have found particulars. Yet, our orders were not to question, but simply to get on with assignments promptly, accomplishing this by seeking out new sources for the purpose.
I can recall the sudden expert on Constantine the Great I became during those heady days. I lectured anyone who would listen to those historical facts I myself had only just acquired. His eager approach to a new religion of the time, his conversion to Christianity so emphasized in school history was in hardly ardor on his part. His urge might be accounted for by a politically-motivated need to save his decaying realm far more than by a 'divine inspiration'. Then too, along came his subsequent ascendance to undisputed mastery of the West — in Europe and Africa — together with his reform of the army. Above all, his accomplishments by the time his rule ended allowed for his overseeing the growth of a Constantinople that was to rival the former splendor of Rome, giving that city not merely world power but a lavish magnificence of its own.
So it went with every endeavor, until I had been finally elevated to tackling the most complex artistic assignments at Grolier. One, I recollect having undertaken when a coupon bearer posed the philosophical question: "What is the true nature of a painting?" The inquirer followed with, "And what constitutes such a creation? What kind of materials does one employ in these works? Just how do I distinguish a competent piece from a masterpiece?"
To recollect it even now strikes me as rather daunting. Suddenly, I found myself contemplating the essence of art itself, and in a hurry yet! Yet such were our preoccupations in that Grolier office. Exalted thought, awesome learning, and a pay check on Friday too!
Curiously withal, what came as most welcome in the working situation was our freedom of movement. When you consider that was my earliest experience with a daily job, little question I'd landed in a dream world. What with seeking out libraries, consulting experts of various sort on many subjects, the gathering of remote sources, we scarcely spent time at our desks but for those hours when completing a project. We would return to a typewriter just to produce and send off our stuff to a waiting subscriber.
I've often wondered whether that initiation to the world of work spoiled me for office employment? Perhaps. But considering the learning I acquired during that time, the incredible rate at which it was imparted, not to speak of the solid introduction it provided for producing serious knowledge on demand, I can only doubt that. From that Grolier experience, I found skills to meet deadlines, and discovered how to manage my time in any future research.
So it was that I came to understand disciplined methods by which to structure whatever material into cogent ideas to satisfy an audience. It opened doors, paved a way to a continuing career, not in research itself, but in magazine and newspaper journalism. And later still, it worked wonders for me in the writing my books. Who would fault such a lucky start?


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text: moshiposhi 0 Posted September 5, 2013 Hi, i have the same problem. It´s hard to control the volume with the master volume. When i turn the volume 1 mm then its going up to the full volume and my ears nearly explode. I play my valve in my arpartment and so its hard to control the volume. I do at the moment a workaround that I use the "Channel Volume" but everytime i switch to another sound, the volume is going to maximum. The master volume is currently not to control with the knob. Do you have an idea, what i can do with this knob ? Can i use any spray. Is is hard to pull the know out, that i can use contact spray ? Regards moshiposhi Quote Share this post Link to post Share on other sites


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IMO the risk of disease is less with packages. Packages only come from commercial producers, it is very easy to research what sources people have good luck with and what sources to avoid. With a nuc it is more important to get a good recommendation for a supplier... Anybody can raise a nuc and they may be full of disease.
If I wanted to purchase a nuc as somebody who was new to beekeeping I would ask on here who to go with. Buy from the members who have a long history on the forum and frequent posts. It shows that they have a reputation with the forum which they value so they are less likely to sell a bad product that word of will resurface on the forum. Members with few posts and/or a short history can just as easily sell a bad product and then resurface under a new user name.
Avoid searching for random websites when looking for nucs... you never know what you will get. I know of one person selling "Northern Survivor" stock at a premium, but on their website it states that their mother queens come from a supplier in Southern California. There are all kinds of shady deals out there... which is why I would only go with good recommendations from either this site or your local bee association.


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Jim Blix
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- 1980
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|- Registered as a JHHS Class of 1980 alumni. 2010


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Has anyone ever heard of Koukou Debut?
Summary [taken from Aicoalition]: Haruna Nagashima gave her all to softball in middle school, and now that she's made her high school debut she's decided to give her all for a new goal. Getting a boyfriend and falling in love! However, she has one small problem. Since she never paid any attention to fashion or trend in middle school she has no idea how to go about attracting her yet-to-be-found love. But a chance encounter with with Yoh Komiyama provides her with the opportunity she needs. If he coaches her in how to become attractive, surely she can find herself a boyfriend!
http://www.aicoalition.com/images/manga/koudebut.png << is a link to a picture of the main characters.
It's a really cute manga, filled with all sorts of wackiness, bad outfits and humor.
Rating wise... on a scale from 1-10, (one being worse, ten, best) it'd get a ... 7-8ish. Not because it's not enjoyable, but because my tastes are actually quite different from what the manga is. But, the manga is so fun that I like it anyway, despite it not being my type (WHICH IS WHY YOU GUYS HAVE TO READ IT). It's a overall, very light, funny, romantic type of manga that's so wacky it can pass the border between fantasy and wacky at times, but it'll surprise you here and there by the sincerity and devotion it shows between characters when you least expect it. It can be cliched at times, but what works of fiction aren't? So far, it's on chapter 24, scanlated-wise, (to my knowledge at least) but it has a lot to develop, so stick around!
My favorite characters are actually Asaoka and Assa-chan. Assa-chan is so creepy and cute that it's hard not to love her ^^"
If you haven't read it, go now! If you have, what are your thoughts on it?
hmmm i read a couple chapters of it a few months ago, but i wasn't interested so i stopped ^^;; but if you say it's really good, i might pick it up again _________________Never underestimate the power of stupid people in large groups.
I like this series too!! The couple are like first time falling in love.
Boku tachi is doing it, and they are aroudn Vol. 6.
Thought is best to say it here, before you pick up this series
Oh, it's really good ^^ At least the first couple of volumes! I totally agree with you about it needing some developing! I saw the raws for the recent chapters and well they seem a bit "flat" and kinda like oneshots... the author ought to make a more steader red thread that one can follow througout the series. The humour is great, but yeah I would like some real story development._________________Thanx to Joanne Kuang for the awesome avatar!
Needs more scans. </3_________________
i agree:D i love this manga to bitsssssssss.
omggg love kokou debut!!
last chapter i read was like chapter 25
sry guys but i have some news...it was lincesed(by Viz i think)...and it was dropped by boku tachi and everyone else...so no more...and it makes me angryyyyyy
I really like this one too!! love the way the romance between the 2 characters, haruna and yoh develop - especially when the gal's so "rough" and forward... she's really fun to watch and her romance seems so pure! another interesting one is the romance between the sister and the other guy... they're so cute together too!!
I love Koukou Debut
It's just so cool and so different from the shoujo mangas I usually read. Haruna is really cute, especially her personality. Yoh and Haruna have wonderful chemistry ^^ It's really sad that Boku Tachi has dropped Koukou Debut, I wish to see it published in my country soon
I love koukou debut!!
At first, I think this manga will end when harunaXYoh ended up together and there's no story about them...but I'm glad I was wrong!!
I love their relationship! It's so funny and yet so romantic!It's funny to see haruna who loves shoujo manga and Yoh who didn't like stuff like that!!
Even when there are some rivals for yoh (that is soo shoujo manga!) but the mangaka really make it different!!
can't wait for the new volume!!
Originally posted by mami:
sry guys but i have some news...it was lincesed(by Viz i think)...and it was dropped by boku tachi and everyone else...so no more...and it makes me angryyyyyy
GAH! I feel the same way. I feel like I'm in a paradox: I want them to license my favorite manga, then if they do I have to wait months for them to catch up for anything new!
Originally posted by mami:
sry guys but i have some news...it was lincesed(by Viz i think)...and it was dropped by boku tachi and everyone else...so no more...and it makes me angryyyyyy
aah! this manga is SO cute! Even though I think Haruna can be annoying sometimes with her whole "I'm dense and the slightest touch of a dude makes me pass out, etc"
though it does call for alot of funny situations.
Definitely though, Yon is so cute when he shows his affection, I love this couple and series!
this is one of my favourite shoujo manga! haruna and yoh are just too sweet to be true! sometimes i just wish i could be as dense and innocent as her...
volume 10 is coming out! can't wait~!
Koukou Debut is adorable!!
Viz is releasing it as High School Debut. Boo. T_T Good for the mangaka, I guess, but their title is so much worse than Koukou Debut!!
It's adorable, cute, and not high drama, but people going through the funny parts of their life as they grow. And how to REALLY treat and grow in a relationship. How it's suppose to be take and give, not submission. How both needs to make an effort and do something nice for each other, not just male OR female. But that you should never completely think this, but just do it because you want your other half to be happy.
It's such a heartwarming, funny, adorable manga. ^^ And the art is so feel-good too! It makes me want to smile right back. It has a happy quality to it, though at first glance, you'd think it was normal shoujo style. The mangaka has some great qualities to her art that makes it stand out though, and thank god it's not one of those chibi chibi mainstream manga like say, H3 (I like H3, don't get me wrong, but it's art is like that).


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**Thanks to Jonathan Miller for bringing this to the HREB's attention.
"We were actually shocked they did this," says Scott Simon, who as the head of the giant bond fund PIMCO's mortgage-backed securities team is one of the world's biggest mortgage bond traders. "It seemed so out of line with their mission."
The trades "put them squarely against the homeowner," he says.
Freddie Mac Bets Against American Homeowners
by Jesse Eisinger, ProPublica and Chris Arnold, NPR News Jan. 30, 2012, 5 a.m.


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Black Jack (GN 4)
Title: Black Jack
Volume: GN 4
Pages: 300
Distributor: Vertical
Release date: 2009-03-03
Suggested retail price: $16.95
Age rating: 13+
Black Jack is a mysterious and charismatic young genius surgeon who travels the world performing amazing and impossible medical feats. Though a trained physician, he refuses to accept a medical license due to his hatred and mistrust of the medical community's hypocrisy and corruption. This leads Black Jack to occasional run-ins with the authorities, as well as from gangsters and criminals who approach him for illegal operations.
Black Jack charges exorbitant fees for his services, the proceeds from which he uses to fund environmental projects and to aid victims of crime and corrupt capitalists. But because Black Jack keeps his true motives secret, his ethics are perceived as questionable and he is considered a selfish, uncaring devil.
Story and art by Osamu Tezuka.
(added on 2008-08-18, modified on 2008-08-18)
- Encyclopedia information about Black Jack (manga)


text:
As the world's leading specialist recruiting company, we want the very best people to join us as experts.
Find us on Facebook and engage with us on what you would like to know.
If you actually joined Hays, what would you first day, your first month, your first year be like?
Have you got what it takes to succeed in the world of professional recruitment?
© Hays Specialist Recruitment 2000 - 2011. All rights reserved.


text:
If you aren't requesting an audit of something, or if you don't work for something that somebody wants audited, you're a nobody in California politics today.
Yes, Sacramento has gone audit crazy.
Everyone is over-compensating, of course. The revelations of $54 million in hoarded state parks funds and small discrepancies in special funds have suddenly made auditing popular. Everyone wants to know where the money is -- or wants to make whatever entities they dislike spend time under the microscope.
U.S. & World
Legislators are calling for an audit of the state's mental health fund, created by Prop 63. Business interests want an audit of the Air Resources Board, which has been a target of their criticism.
And everyone wants to audit every inch of the state parks department. Yesterday.
Since I don't want to be left out, why don't we audit the University of California? Or the Public Utilities Commission? Or the state auditor?
How can you have audits if you don't trust the auditor?
All the auditing might be healthy -- if it weren't so misleading to a public that already knows too little about how the state works.
Californians still believe that the state's problems are merely a matter of poor accounting or waste.
There's both, of course, but not enough to explain the state's financial problems.
California is short of money because it can't govern itself, because there are so many tax and spending rules locked in place that planning, management and tradeoffs aren't possible.
The one audit that the state could really use is a performance audit -- of the voters who have constructed this broken system over the generations.
Because the big question is not what cash is in which account today.
The big question is why there are so many accounts in the first place--and why it's so hard to keep track of all of them.
Lead Prop Zero blogger Joe Mathews is California editor at Zocalo Public Square, a fellow at Arizona State University's Center for Social Cohesion, and co-author of California Crackup: How Reform Broke the Golden State and How We Can Fix It (University of California, 2010).
Send us your thoughts via Twitter @PropZero or add your comment to our Facebook page.


text:
- Description
|Item NO.:
|11053.png" title="733a611053.png" alt="blob.png"/>
|tempered bent glass 12mm
|1PC/1CTN;Carton and wooden box
|Delivery time:
|40 days after we get L/C or T/T deposit
Introduction of our company:
LANGFANG KAILIDE FURNITURE CO., LTD is a comprehensive glass process manufacturer,
which is located in the south of Beijing-Langfang Development Zone, China, and was
founded in 2000. It has nearly 160 employees and covers an area of 50 acres with convenient
Our company is engaged in research, development, production, design, and sales of tempered
glass, bent glass, steel and wood furniture, such as coffee table, nesting table, side
table, console table and TV stand.
All the producing lines are equipped with the most advanced facilities in China and around
the world. And we have professional designer, senior engineers and high quality production
team. Our products have passed the rigorous test and get the quality certification of
ITS. As a result, our products sell well at home and also enjoy popularity in more than 10
countries and regions, such as France, Germany, Italy, Croatia,United Kingdom, Spain,
Switzerland, Australia, New Zealand and so on. After more than 10 years, our company has
established good cooperation with international furniture companies.
Our company has strong financial power with talents, management, service, technology
and machine. We always keep the principle in our mind---"Pacing with technology, Living
with quality, Serving customers first, Being the best". We are making great efforts to meet
and satisfy the demands of markets and clients with good quality in both products and
We highly recommend you to visit our website and please do not hesitate to give us your
requests, we thank you for giving us this opportunity to serve for you and look forward to
establish a good and long business relationship with your honor company.
Product and packing:


text:
Sunday, September 02, 2012
Hills Make You Strong
Great long run today, hitting every big hill within a five mile radius of my house including Ossipee Hill (summit is 1034'). Total elevation gain for the run was 1722'. Pace was pretty easy, but the good news is it felt easy and I even picked things up in the end.
Before I got to Ossipee Hill, I ran up Deering Ridge and down the hill to the town hall. Pretty uneventful and I just got into the grove during that seven mile portion. Then I hit Ossipee Hill. It's about a two and a half mile climb to the top, gaining 720' in the process. This was the first time that I ran the whole thing. There are a couple of sections that are wicked steep and in the past I would just power hike them, but today I raised the bar and ran up the entire route non-stop.
Climbed up the firetower once I was there and took in the panoramic views at the top. I could clearly see the ocean, Mt. Washington and even Portland. Hung out there for about seven minutes and then ran back down.
Next climb was up to Robert's Ridge Road, which seemed like a mere speed bump after Ossipee. Down that, and then up Bennet Hill Road and then looped around back home.
This capped off a great training week that turned out to be pretty hill specific, including this run, the run up Cadillac the other day and a tempo run on hills earlier in the week. Quite pleased and good hay in the barn for MDI. Weekly total now stands at 58.6, and I just might be a nerd and go out later for a couple of miles to get over 60 for the week.
Ran 20.5 miles @ 8:16/mile pace.
Paved roads, dirt roads, jeep trails.
Extremely hilly.
Lower 60s, overcast, light rain.
Saucony Kinvara 3, shorts, short sleeved shirt, handheld bottle (diluted Gatorade).
Posted by jamie at 12:48 PM
3 comments:
- Jeremy Bonnett said...
That sounds like a hell of a run man! Love to join you on that one sometime.
- jamie said...
Ya know, it occurred to me during the run that I should have asked if you wanted to join me. Next time for sure, even if we just do Ossipee. It's a great hill run. I bet Jeff would love it as well.
- middle.professor said...
I would...if you shrunk the distance 25%
Subscribe to: Post Comments (Atom)


text:
Episode 8 Preview
Preview: Season 8 Episode 8 | 30s
Share in the Turners' emotions over May's impending adoption. Sister Hilda digs deep to give a terminally ill patient her final wish. Valerie and Trixie must testify in a grueling court case. Fred and Reggie keep secrets from each other.
Aired: 05/19/19Video has closed captioning.
The full episode is no longer available for online streaming. Why?
Please continue to enjoy extra(s) from this episode. The full episode is still available for purchase through the "Buy Now" links.
Buy Now:
Problems Playing Video?
Call the Midwife Season 8, Episode 8 GIF Recap
Before this last episode, Season 8 has already taken us on quite the adventure.
When the Past Reveals the Problems of Today's Choices
Andrea Altomaro on what this Season 8 says about abortion laws.
The Poetry of Life
Deborah McBain on the importance of supporting roles.


text:
From HaskellWiki
< HaskellImplementorsWorkshop
Revision as of 12:45, 1 March 2011 by Benl23 (talk | contribs) (→Haskell Implementors Workshop 2011)
Haskell Implementors Workshop 2011
The Haskell Implementors Workshop is an informal affair with no proceedings, just talks from people involved in building tools, infrastructure, or libraries for Haskell development. The aim is for this workshop to give the people involved with building the infrastructure behind this ecosystem an opportunity to bat around ideas, share experiences, and ask for feedback from fellow experts. There is usually a mixture of short talks, longer talks, discussion and demos.
The Haskell Implementors Workshop will run again this year, co-located with ICFP 2011. A call for talk proposals will be distributed towards the end of March.
Important Dates
- Workshop: Friday 23rd September, 2011
- Rebekah Leslie (Portland State University)
- Ben Lippmeier - co-chair (University of New South Wales)
- Andres Löh (Well-Typed LLP)
- Oleg Lobachev (University of Marburg)
- Neil Mitchell - co-chair (Standard Chartered)
- Dimitrios Vytiniotis (Microsoft Research)


text:
Autologous Transplant in HIV Patients (BMT CTN 0803)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01141712
Recruitment Status : Completed
First Posted : June 10, 2010
Results First Posted : March 28, 2017
Last Update Posted : October 27, 2017
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Lymphoma HIV
|Procedure: Autologous transplant Drug: BCNU Drug: Etoposide Drug: Cytarabine Drug: Melphalan
|Phase 2
Non-Hodgkin lymphoma (NHL) is an AIDS-defining diagnosis for patients infected with the Human Immunodeficiency Virus (HIV). While the incidence of NHL has decreased amongst HIV-infected patients since the advent of highly-active anti-retroviral therapy (HAART), lymphoma remains a significant cause of death for this patient population. The prognosis for patients with AIDS-related lymphoma is dramatically different in the era of HAART therapy. In a comparison of treatment outcomes for patients treated before and after the advent of HAART, there is a statistically significant improvement in the overall survival of patients treated with HAART. Unfortunately, despite considerable advances in the treatment of AIDS-related NHL, induction-failure and disease relapse remain key challenges. The prognosis for patients with refractory and relapsed NHL is poor with overall survival rates of less than 20 percent for patients treated with non-transplant salvage therapies. Based upon a randomized trial and numerous phase II trials, high-dose therapy with autologous hematopoietic cell transplantation (HCT) has been established as the standard of care for patients with chemotherapy-sensitive relapsed non-Hodgkin lymphoma.
All patients must have chemosensitive disease as demonstrated by response to induction or salvage chemotherapy. Patients must also have less than or equal to 10percent bone marrow involvement after their most recent salvage therapy. Patients cannot have had prior autologous or allogeneic HCT. Patients must initiate conditioning therapy within 3 months of mobilization or bone marrow harvest.
Mobilization therapy may be employed per institutional guidelines. Patients must have an adequate autograft to be eligible for the protocol. Patients may not have HIV refractory to pharmacologic therapy. Patients must not have opportunistic infection that is not responding to therapy. Patients will receive Carmustine (BCNU) 300 mg/m^2 Day -6, Etoposide 100 mg/m^2 twice a day (BID) on Days -5 to -2, Cytarabine 100 mg/m2 BID on Days -5 to -2, and Melphalan 140 mg/m2 Day -1 followed by autologous HCT.
Patients will be followed for 2 years post-transplant. Survival data, time to progression data, progression-free survival data, time to progression after Complete Remission (CR) data, lymphoma disease-free survival data, time to hematopoietic recovery data, hematologic function data, toxicity data, incidence of infections, treatment-related mortality data, immunologic reconstitution data, data assessing the impact of therapy on the HIV reservoir and microbial gut translocation will be recorded and reported periodically to the BMT CTN Data and Coordinating Center (DCC).
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|43 participants
|Intervention Model:
|Single Group Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|High Dose Chemotherapy With Autologous Stem Cell Rescue for Aggressive B Cell Lymphoma and Hodgkin Lymphoma in HIV-infected Patients (BMT CTN #0803)
|Study Start Date :
|April 2010
|Actual Primary Completion Date :
|May 2015
|Actual Study Completion Date :
|June 2016
Autologous transplant
Patients will receive BCNU 300 mg/m^2 Day -6, Etoposide 100 mg/m^2 BID Days -5 to -2, Cytarabine 100 mg/m^2 BID Days -5 to -2, and Melphalan 140 mg/m^2 Day -1 followed by autologous HCT.
Procedure: Autologous transplant
Participants will receive the BEAM conditioning regimen followed by autologous HCT.
Drug: BCNU
Participants will receive BCNU 300 mg/m^2 Day -6
Other Name: Carmustine
Drug: Etoposide
Participants will receive Etoposide 100 mg/m^2 BID Days -5 to -2
Other Name: VP-16
Drug: Cytarabine
Participants will receive Cytarabine 100 mg/m^2 BID Days -5 to -2
Other Name: Depocyt
Drug: Melphalan
Participants will receive Melphalan 140 mg/m^2 Day -1
Other Name: Alkeran
- Overall Survival (OS) [ Time Frame: Year 1 and 2 ]Assess the OS after autologous hematopoietic stem cell transplantation (HCT) for chemotherapy-sensitive aggressive B cell lymphoma or Hodgkin's lymphoma in patients with HIV using BEAM for pre-transplant conditioning. The primary analysis will consist of estimating the 1 year OS probability from the time of transplantation based on the Kaplan-Meier product limit estimator. The 1 year and 2 year OS and confidence interval will be calculated.
- Relapse/Progression [ Time Frame: Year 2 ]Relapse is defined as the appearance of any new lesion more than 1.5 cm in any axis during or at the end of therapy, even if other lesions are decreasing in size. Progression is defined as a lymph node with a diameter of the short axis of less than 1.0 cm must increase by >= 50% and to a size of 1.5 x 1.5 cm or more than 1.5 cm in the long axis.
- Progression-Free Survival (PFS) [ Time Frame: Year 2 ]The time to this event is the time from enrollment until death, relapse/progression, receipt of anti-lymphoma therapy, or last follow up, whichever comes first. Progression-free survival (PFS) will be estimated using the Kaplan Meier product limit estimator. The PFS probability and confidence interval will be calculated at two years post-transplant.
- Complete Remission (CR) and/or Partial Response (PR) [ Time Frame: Day 100 ]The frequencies and proportions of patients who have a CR or PR. CR is defined as the disappearance of all evidence of disease, and PR is defined as the regression of measurable disease and no new sites.
- Time to Progression After CR [ Time Frame: Year 2 ]This will be assessed in patients with CR. Patients are considered failure for this end point if they relapse after complete remission. Surviving patients with no history of relapse/progression are censored at time of last follow-up.
- Lymphoma Disease-free Survival [ Time Frame: Year 2 ]This will be assessed in patients with CR. Patients are considered failure for this end point if they die or if they relapse after complete remission. Patients with no history of relapse or death after complete remission are censored at time of last follow up.
- Cumulative Incidence of Neutrophil Recovery [ Time Frame: Day 28 ]Neutrophil recovery is defined as two consecutive days of absolute neutrophil count (ANC) > 500 neutrophils/μL following the expected nadir.
- Cumulative Incidence of Platelet Recovery [ Time Frame: Day 100 ]Platelet recovery is defined as a platelet count greater than 20,000/μL for the first of two consecutive labs with no platelet transfusions 7 days prior.
- Hematologic Function [ Time Frame: Days 100 and 365 ]Hematologic function will be defined as ANC > 1500 neutrophils/μL, Hemoglobin> 10g/dL without transfusion support, and platelets > 100,000/μL
- Number of Participants Experiencing Toxicity [ Time Frame: Year 2 ]Toxicities will be defined by using the version 3.0 NCI Common Terminology Criteria for Adverse Events (CTCAE) criteria. Only grade 3 and higher toxicities will be collected.
- Number of Participants Experiencing Infections [ Time Frame: Year 1 ]Microbiologically documented infections will be reported by site of disease, date of onset, severity, and resolution, if any.
- Treatment-Related Mortality (TRM) [ Time Frame: Day 100 ]TRM is defined as death occurring in a patient from causes other than relapse or progression. A cumulative incidence curve will be computed along with a 95% confidence interval at 100 days post-transplant.
- Immunologic Reconstitution [ Time Frame: Year 1 ]Immunologic Reconstitution will be assessed by quantitative immunoglobulin measurement (IgM, IgG and IgA)
- HIV Single-Copy Polymerase Chain Reaction (PCR) [ Time Frame: Baseline, Days 100, 180, 365, and 730 ]HIV RNA assay will be performed at the specified time points and summarize the assessments of the viral copy number using descriptive statistics.
- Microbial Translocation Markers [ Time Frame: Day 30 and 100 ]Level of microbial translocation markers will be determined by nonparametric Mann-Whitney tests comparing the distribution of prior microbial translocation markers between patients.
- Ig and Epstein-Barr Virus (EBV) DNA in Blood [ Time Frame: Day 100, 180, and 365 ]The presence of clonal Ig DNA in plasma will be assessed, as will EBV copy number in plasma and in peripheral blood
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|15 Years and older (Child, Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Diagnosis of persistent or recurrent World Health Organization (WHO) classification diffuse large B-cell lymphoma, composite lymphoma with > 50% diffuse large B-cell lymphoma, mediastinal B-cell lymphoma, immunoblastic, plasmablastic, Burkitt's or Burkitt-like or classical Hodgkin's lymphoma. Patients transformed from follicular lymphoma are eligible for the study, pending fulfillment of other criteria.
- 15 years old or older
- Three or fewer prior regimens of chemotherapy over the entire course of their disease treatment (including one induction chemotherapy and no more than 2 salvage chemotherapies). Monoclonal antibody therapy and involved field radiation therapy will not be counted as prior therapies.
- All patients must have chemosensitive disease as demonstrated by at least a partial response to induction or salvage therapy.
- Less than or equal to 10% bone marrow involvement.
- Patients with adequate organ function as measured by: a)Cardiac: American Heart Association Class I: Patients with cardiac disease but without resulting limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, dyspnea, or anginal pain. Additionally, all patients must have a left ventricular ejection fraction at rest greater than or equal to 40% demonstrated by Multi Gated Acquisition Scan (MUGA) or echocardiogram; b)Hepatic: (i) Bilirubin less than 2.0 mg/dL (except for isolated hyperbilirubinemia attributed to Gilbert syndrome or antiretroviral therapy) and alanine transaminase (ALT) and aspartate transaminase (AST) greater than 3x the upper limit of normal; (ii) Concomitant Hepatitis: Patients with chronic hepatitis B or C may be enrolled on the trial providing the above criteria are met. In addition, no active viral replication - undetectable (viral load less than 500 copies/ml) hepatitis B DNA level by PCR and no clinical or pathologic evidence of irreversible chronic liver disease; c)Renal: Creatinine clearance (calculated creatinine clearance is permitted) greater than 40 mL/min; d)Pulmonary: Carbon Monoxide Diffusing Capacity (DLCO), forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) greater than or equal to 45% of predicted (corrected for hemoglobin).
- Autologous peripheral stem cell graft with a minimum of greater than or less than 1.5 x 10^6 CD 34+ cells/kg (target greater than or less than 2.0 x 10^6 CD 34+ cells/kg) or if peripheral blood stem cell (PBSC) mobilization fails, cells can be obtained by bone marrow harvest per institutional practices (in cases where bone marrow will be used for transplantation, the required CD34+ dose does not apply and institutional requirements for total nucleated cell dose should apply).
- Initiate conditioning therapy within 3 months of mobilization or bone marrow harvest.
- Signed informed consent.
- Patients on antiretroviral therapies (ARVs) can either have: a) Undetectable HIV viral load (VL less than 50 copies); b) If VL detectable at less than 2000 copies/mL must have review of previous antiretroviral regimens or previous genotypic or phenotypic testing which indicate the ability to fully suppress virus by addition of sensitive drugs. This review will be carried out by the Infectious Disease (ID) specialist caring for the patient; c)If VL detectable at greater than 2000 copies/mL, a current HIV genotype and/or phenotype must be obtained. If a HAART regimen to which the patient's virus is sensitive can be determined based on genotype and previous antiretroviral experience, then the patient will be considered eligible in this regard. This review will be carried out by the ID specialist caring for the patient.
Exclusion Criteria:
- Karnofsky performance score less than 70%.
- Uncontrolled bacterial, viral or fungal infection (currently taking medication and with progression or no clinical improvement).
- Prior malignancy in the 5 years prior to enrollment except resected basal cell carcinoma, treated cervical carcinoma in situ or Kaposi's sarcoma: a)Symptomatic Kaposi's sarcoma currently requiring therapy is excluded (patients receiving topical therapy for minimal disease are not included in this definition); b)Prior treatment with topical agents, local radiation, or up to 6 cycles of cytotoxic chemotherapy at least six months prior is permitted; c) Other cancers treated with curative intent less than 5 years previously will not be allowed unless approved by the Medical Monitor or Protocol Chair; d)Cancer treated with curative intent more than 5 years previously will be allowed.
- Pregnant (positive β-HCG) or breastfeeding.
- Fertile men or women unwilling to use contraceptive techniques from the time of initiation of mobilization until six-months post-transplant.
- Prior autologous or allogeneic HCT.
- Patients with evidence of Myelodysplastic Syndrome (MDS)/Acute Myeloid Leukemia (AML) or abnormal cytogenetic analysis indicative of MDS on the pre-transplant bone marrow examination. Pathology report documentation need not be submitted.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01141712
|United States, California
|City of Hope National Medical Center
|Duarte, California, United States, 91010-3000
|University of California San Diego Medical Center
|La Jolla, California, United States, 92093
|Los Angeles, California, United States, 90035
|University of CA, SF
|San Francisco, California, United States, 94143
|United States, Florida
|University of Florida College of Medicine
|Gainesville, Florida, United States, 32610
|H. Lee Moffitt Cancer Center
|Tampa, Florida, United States, 33624
|United States, Georgia
|Emory University
|Atlanta, Georgia, United States, 30322
|BMT Program at Northside Hospital
|Atlanta, Georgia, United States, 30342
|United States, Maryland
|University of Maryland Medical Systems, Greenebaum Cancer Center
|Baltimore, Maryland, United States, 21201
|Johns Hopkins Medical Institution
|Baltimore, Maryland, United States, 21231
|United States, Missouri
|Washington University/Barnes Jewish Hospital
|Saint Louis, Missouri, United States, 63110
|United States, New York
|Weill Cornell Medical College
|New York, New York, United States, 10065
|Memorial Sloan-Kettering Cancer Center
|New York, New York, United States, 10174
|University of Rochester
|Rochester, New York, United States, 14642
|United States, Ohio
|Ohio State University Medical Center
|Columbus, Ohio, United States, 43210
|United States, Texas
|University of Texas/MD Anderson Cancer Center
|Houston, Texas, United States, 77030
|Study Director:
|Mary Horowitz, MD
|Center for International Blood and Marrow Transplant Research
Additional Information:
Publications of Results:
|Responsible Party:
|Medical College of Wisconsin
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
U01HL069294 ( U.S. NIH Grant/Contract )
U01HL069294-06 ( U.S. NIH Grant/Contract )
U01CA121947 ( U.S. NIH Grant/Contract )
|First Posted:
|June 10, 2010 Key Record Dates
|Results First Posted:
|March 28, 2017
|Last Update Posted:
|October 27, 2017
|Last Verified:
|October 2016
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
|Plan Description:
|Findings will be published in a manuscript
|Time Frame:
|Within 6 months of official study closure at participating sites.
|Access Criteria:
|Available to the public.
B-cell Lymphoma
Burkitt's Lymphoma
Follicular Lymphoma
Hodgkin's Lymphoma
Neoplasms by Histologic Type
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases
Etoposide phosphate
Antineoplastic Agents, Phytogenic
Antineoplastic Agents
Topoisomerase II Inhibitors
Topoisomerase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Antimetabolites, Antineoplastic
Antiviral Agents
Anti-Infective Agents
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antineoplastic Agents, Alkylating
Alkylating Agents
Myeloablative Agonists


text:
Dundalk Florist
7233 German Hill Road
Dundalk, Maryland 21222
410-284-1600 | 800-287-0136
Monday-Friday: 8 am - 6 pm
Saturday: 8 am - 5 pm
Sunday: 9 am - 3 pm
Search for Flowers
St. Patrick's Day
International Women's Day
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Thank you
Fruit and Snack Baskets
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Product Details
Click Here For Larger Image
DFF367 Woodland Delight Bouq
Item No: DFF367
This design in made in a plastic plaid pot with a deer and saying on the front. Filled with red and white flowers and mixed evergreens. This is a one sided design. Overall design is approx. 15"h x 13"w.
Select Delivery City
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Help & FAQ
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Dundalk Florist
7233 German Hill Road
Dundalk, Maryland
410-284-1600 | 800-287-0136
Monday-Friday: 8 am - 6 pm
Saturday: 8 am - 5 pm
Sunday: 9 am - 3 pm
Dundalk Florist is your full-service, local florist in Dundalk, Maryland.
In business for over 100 years, Dundalk Florist on German Hill Road has been the choice for flowers and gifts for Dundalk, Marlyand and the surrounding areas.
We have the perfect gift for anniversaries and birthdays, and have a friendly and professional staff to assist you with your wedding flowers. We also deliver sympathy flowers to many of the areas funeral homes.
Order online or call our shop today and see the difference with Dundalk Florist!
Florist Website Design by Media99


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Data privacy statement
We are delighted that you are interested in our company and our website. We would like to provide you below with information about the processing of your personal data in connection with your visit to our website.
Who is responsible for the data processing?
The controller within the meaning of the data protection legislation is
HanseYachts AG
Ladebower Chaussee 11
17493 Greifswald
E-mail: firstname.lastname@example.com
You can find more information about our company, the duties of the individual authorised to represent the company and also other options for contacting us in our legal notice.
Our data protection officer
You can contact our data protection officer at:
HanseYachts AG
Attn. Data protection
Ladebower Chaussee 11
17493 Greifswald
E-mail: email@example.com
Your rights as a data subject
If your personal data is processed, you are the data subject within the meaning of the General Data Protection Regulation (GDPR) and you are entitled to assert the following rights against us:
You can ask us to confirm whether personal data that concerns you is processed by us (right of access).
Furthermore, you have to right to rectify incorrect data, a right to object to the processing, the right to restriction of the processing, a right to have your personal data erased and to assert your right to data portability. Should you have reason to believe that we are conducting processing unlawfully, you have the right to submit a complaint to a supervisory authority. You can submit a complaint for example to the supervisory authority that has jurisdiction over us:
Landesbeauftragte für Datenschutz und Informationsfreiheit (State Commissioner for the Protection of Data and Freedom of Information) of Mecklenburg-Vorpommern
Werderstrasse 74a
19055 Schwerin
What data concerning you do we process? For what purposes? On what legal basis?
We process the most varied of data, which you transmit to us while you are visiting our website. We provide a clear presentation of the individual processing for you below.
Provision of the website and creation of log files
Description and scope of the data processing
Each time our website is visited, our system automatically records data and information from the computer system of the requesting, i.e. your, computer.
The following data is collected here:
- IP address of the user
- Date and time of access
- Websites from which the user's system was directed to our website
- Websites that were visited by the user's system from our website
- Volume of data received and sent in bytes
The data is also stored in our system's log files This data is not stored together with other personal data of the user.
Legal basis for the data processing
The legal basis for the temporary storage of the data and the log files is Article 6(1) f) GDPR.
Purpose of the data processing
The temporary storage of the IP address by the system is necessary in order to enable the website to be delivered to your computer. Your IP address has to be stored for the duration of the session for this.
The data is stored in log files in order to ensure that the website functions properly. Furthermore, the data helps us to optimise the website and to guarantee the security of our information technology systems. No evaluation of the data for marketing purposes takes place in this connection.
These purposes are also based on our legitimate interests in the data processing pursuant to Article 6(1) f) GDPR.
Duration of storage
The data is erased as soon as it is no longer necessary to achieve the purpose for which it was collected. If the data is collected in order to provide the website, the data is erased when the current session is ended.
If the data is stored in our log files, it is erased after no more than seven days.
Contact – Your interest in us
Description and scope of the data processing
You have the option on our website of getting in contact with us using a variety of contact forms in order to order a brochure, to submit a general enquiry, to request access to a product configurator or even to arrange a meeting at a boat show.
If you use this option, the data entered on the input screen will be sent to us and stored. This data includes:
Title, given name, family name, address, post code, town, country, e-mail, telephone number, contents / subject matter of your enquiry.
No disclosure of the data to third parties takes place in principle in this connection. We disclose your data to your nearest specialist dealer, who will process your enquiry. The data is used in principle only for processing the enquiry.
Legal basis for the data processing
The legal basis for processing the data is provided by Article 6(1) f) GDPR. If the purpose of getting in contact by e-mail is to enter into a contract, an additional basis for the processing is provided by Article 6(1) b) GDPR.
Purpose of the data processing
The processing of the personal data helps us to answer your enquiry. These purposes are also based on our legitimate interests in the data processing pursuant to Article 6(1) f) GDPR. We take care in this connection that we process only the data from you that is actually required.
Duration of storage
We store your data in our management system. The data is erased as soon as it is no longer necessary to achieve the purpose for which it was collected, its erasure is not in conflict with any statutory retention requirements (10 years) and it is no longer required for our interests. We conduct a regular review every two years to this end.
Newsletter data
If you would like to access the newsletter offered on the website, we need to have your email address as well as information allowing us to check that you are the owner of the email address provided and that you agree to receive the newsletter. Additional data are not collected or are collected only on a voluntary basis. We use these data exclusively for sending the information requested and do not disclose them to third parties.
The data entered on the newsletter registration form are processed exclusively on the basis of your consent (Article 6(1a) GDPR). You may use the "unsubscribe" link in the newsletter at any time to withdraw the granted consent to save the data, email address and the use thereof for sending the newsletter. The lawfulness of any data processing already carried out is not affected by this withdrawal.
The data kept by us for the purposes of receiving the newsletter will be saved by us until you unsubscribe from the newsletter and will be deleted after the newsletter stops. Data that are saved by us for other purposes are not affected by this.
Description and scope of the data processing
We use cookies to operate our website. Cookies are small text files that are automatically stored on your system by your browser. We use what are known as session cookies in order to make our website easier to use and fully functional. Furthermore, we use what are known as "persistent cookies" in order to analyse search behaviour, but also to measure the reach of the website with the help of Google Analytics and Facebook. You will find more information on the use of cookies for marketing purposes and for the measuring the reach in this statement.
Legal basis for the data processing
The legal basis for processing the data is provided by Article 6(1) f) GDPR.
Purpose of the data processing
We process this data for the purpose of the commercial operation of this website. This purpose is also based on our legitimate interests in the data processing pursuant to Article 6(1) f) GDPR.
Duration of storage
Session cookies are deleted after you leave our website or at the latest when you close your browser. The persistent cookies that we and third parties such as Google use are valid for between 24 hours and two years depending on their function.
Opt-out and rectification option
You can switch of the use of all cookies in the basic settings of your browser. This can mean, however, that our website will no longer be fully functional. Furthermore, you can object to the use of cookies for advertising purposes and for the measurement of the reach (opt out). You can use the following websites for this for example: http://optout.networkadvertising.org/ or http://www.youronlinechoices.com/uk/your-ad-choices/
Web analysis using Google Analytics
Description and scope of the data processing
We use Google Analytics on our website to analyse your surfing behaviour. The software places a cookie on your computer (see the section on cookies above). The following data is stored if individual pages of our website are visited:
- Three bytes of the IP address of the user's client system
- The website visited
- The website from which the user came to the website now being visited (referrer)
- Sub-pages that are visited from the website being visited
- Time spent on the website
- Frequency of visits to the website
- Origin (country and town)
- Language
- Operating system
- Device (PC, tablet PC or smartphone)
- Browser
- Screen resolution
- Traffic sources
- Downloads
- Retrieval of specific URLs
- Interactions with the website (clicks)
The Google Analytics software is a service offered by Google LLC, 1600 Amphitheatre Parkway, Mountain View, CA 94043, USA (Google). All data is (generally) transmitted to Google servers in the US and stored there for processing.
In order to guarantee that European data protection law is complied with, Google has signed the Privacy Shield Framework
We have set up Google Analytics so that the IP addresses is not stored in full, but with the last byte of the IP address masked. This means that the IP address counts as anonymised and there is no possibility of identifying you through it.
Collecting the specified data allows us and the other clients of Google's advertising services to display advertisements to you that might match your interests.
The stored data is used by Google among other things in order to analyse and compile reports on the usage behaviour on our website.
We are able to use these services on the one hand through a direct connection and, on the other, by using the "Google Tag Manager".
Legal basis for the data processing
The legal basis for processing the personal data of the user is provided by Article 6(1) f) GDPR.
Purpose of the data processing
The processing of your personal data enables us to analyse surfing behaviour. Thanks to the analysis of the data acquired, we are able to compile information about the use of the individual elements of our website. This helps us to constantly improve the commercial operation of our website and its user-friendly design, but also to configure target group-specific advertising. These purposes are also based on our legitimate interests in processing the data pursuant to Article 6(1) f) GDPR. Your interest in the protection of your personal data is taken into satisfactory consideration by the anonymisation of your IP address.
Duration of storage
We have set up the Google services in such a way that the data is erased after 26 months, as we no longer need this data for analysis and processing purposes after that time,
Opt-out and rectification option
Cookies are stored on your computer and sent from there to our page when you use our website.. As a user, therefore, you also have full control over the use of cookies. You can deactivate or restrict the transfer of cookies by changing the settings in your Internet browser. Cookies that have already been stored can be deleted at any time. This can also be done automatically. If cookies are deactivated for our website, it may no longer be possible to use all the functions of the website to the full extent.
You can restrict or prevent the processing of the data mentioned above. Google provides a browser plug-in for this: http://tools.google.com/dlpage/gaoptout?hl=de.
Google provides you with more information on the use of the data, settings options and how to submit an objection:
"Use of data by Google when you use websites or apps of our partners" – https://www.google.com/intl/de/policies/privacy/partners, "Use of data for advertising purposes" – http://www.google.com/policies/technologies/ads and "Managing information that Google uses to show you advertising" - http://www.google.de/settings/ads.
Use of content and services of third parties
Description and scope of the data processing
We use various technologies and services of third parties on our website. These include, for example, map services, technologies to filter spam in forms, but also the embedding of videos in blog entries. Data from you will therefore also be forwarded to third parties when your visit our website. This includes your IP address. We endeavour always to use service providers who use your data only for the relevant visit. The following are used:
- Services of the provider Google Inc., 1600 Amphitheatre Parkway, Mountain View, California 94043, United States. When these services are used, data is transferred from and to Google services mainly in the US. You will find Google's data privacy policy at: https://policies.google.com/privacy. You can adjust the use of your data by logging in to your Google account: https://adssettings.google.com/authenticated Specifically, we use the following Google services:
- We use the Google Maps map service to display maps.
- Fonts of the service provider "fonts.com" Monotype GmbH, Werner-Reimers-Strasse 2–4, 61352 Bad Homburg. Each time you visit our website, font data from this service provider is loaded so that our website can be displayed in accordance with our settings. This embedding is also necessary for the billing of the licensing fees for the relevant font. You can find more information on the use of data, the responsibility of "fonts.com" and settings options in its data protection policy (https://www.monotype.com/legal/privacy-policy).
- Services of the provider "JWPlayer" LongTail Ad Solutions, Inc., d/b/a JW Player, 2 Park Avenue, 10th Floor, New York, NY 10016, USA. The video player provided by JWPlayer is used on our website. If you visit our website and a video is played back using this video player, your browser transmits information on this to the developer. We do not use other forms of tracking in the videos using JWPlayer. You can find more information on the use of data, the responsibility of "JWPlayer" and settings options in its data protection policy (https://www.jwplayer.com/privacy/).
In addition to the service providers expressly specified here, other service providers may also be used that we require to provide the website or individual content. It is possible that personal data will be transferred to these service providers in this process. We ensure in principle that we conduct a careful analysis and use only service providers that can guarantee an appropriate level of security.
Legal basis for the data processing
The legal basis for processing the data is provided by Article 6(1) f) GDPR.
Purpose of the data processing
We process this data for the purpose of the commercial operation of this website. This purpose is also based on our legitimate interests in the data processing pursuant to Article 6(1) f) GDPR.
Reference texts
We process your data in principle only to process your enquiry. To this end, we transmit this data to the nearest authorised dealer so that they can advise you concerning your enquiry and send you offers and brochures. You can find further statements on this in our data privacy policy.
We process your data in principle only to process your enquiry and to provide access to our press releases in connection with that. You can find further statements on this in our data privacy policy.
We process your data in principle only to provide and to operate our newsletter. You can find further statements on this in our data privacy policy.
Appointment at dealers and certain boat shows:
We process your data in principle only to process your enquiry. To this end, we transmit this data to the authorised dealer you have selected so that they can advise you concerning your enquiry and send you offers and brochures. You can find further statements on this in our data privacy policy.


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Who's waiting for marriage? Not even evangelicals, it seems.
Eighty percent of evangelicals are sharing the marriage bed before marriage.
(Flickr photo cc by Quiet Here)
Despite the widespread prevalence of chastity rallies, purity rings, abstinence pledges, and popular guides to varying levels of intimacy, it turns out that evangelicals are having sex outside of marriage just as much as everyone else. An article in the September/October issue of Relevant reports that "80 percent of young, unmarried Christians have had sex. Two-thirds have been sexually active in the last year." The number is only slightly higher when you look at all of 18-29-year-olds, 88 percent of whom are having sex before tying the knot.
The story begins with a young woman who stayed a virgin until 20 and had planned to stay one until she was married. Why did she change her mind? A lack of role models and the fact that all of her other Christian friends were doing it.
The subsection of the article titled, "Why waiting is so hard," goes onto theorize that "the media's marketing of sex, the cultural endorsement of the 'do what feels good' mentality, the prevalence of pornography, and the widespread misunderstanding of sex that prompts people to chase after love and acceptance in unhealthy physical relationships are all factors that make it difficult to practice chastity." Further reasons include the church not placing a high enough value on marriage (to which I'd respond, "What church are you from?"), the need to talk more openly about "God's intention and design and purposes [for sex]," and the notion that "our culture wants to convince us sex is really about two bodies coming together for a great time."
Note how in all of these reasons the blame is placed on the wider culture, never on the individuals, and certainly not on the way Christians talk—or rather, don't talk—about sex.
I don't disagree that popular culture plays a roll in influencing young people's sexual behavior. Having watched a few episodes of MTV's Awkward, I've experienced my fair share of disgust at the nonchalant writing about a 15-year-old having clandestine sex with a boy who isn't even willing to hold her hand in public. But I'm frustrated with how the story passes off the blame to a "hyper-sexualized society where sex is constantly available," while never questioning the personal responsibility of the "offenders" and only mildly addressing the revising of the message of abstinence at the very end of the article.
Plus, all this blame on popular culture is backed up by zero evidence. I'd like to know how many Christians were having sex before marriage 20, 30, and 40 years ago. Where are the stats that show popular culture is any more sexualized now than in 1960? You'd be hard-pressed to find anything to back that up, and might even find evidence to the contrary.


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Oscar De la Renta Cerulean Printed Cashmere Bead Embroidery Coat, Circa: 2000's
- Designer
- Brand
- In the Style OfClassic
- Place of OriginUnited States
- Period
- ConditionExcellent
- DimensionsD 50 in.D 127 cm
- Marked Size8 (US)
- Bust36 in. (91.44 cm)
- Waist36 in. (91.44 cm)
- Hip44 in. (111.76 cm)
- Length50 in. (127 cm)
- Seller LocationCincinnati, OH
- Reference NumberLU2548687532
Shipping, Returns & Payment
- Shipping$70Standardto anywhere in the world, arrives in 1-2 weeks.Delivered by a parcel delivery service such as UPS, FedEx, or DHL.Shipping methods are determined by item size, type, fragility and specific characteristics.Shipping costs are calculated based on carrier rates, delivery distance and packing complexity.
- Return Policy
This item can be returned within 1 day of delivery.View details
- Online Payment Methods1stdibs accepts the following payment methods
- Item InvoiceGenerate an invoice that you can customize and print.
About Oscar De La Renta (Manufacturer)
Oscar de la Renta was not just a designer for the ages but a designer for women of all ages — from Hollywood starlets to silver-haired doyennes, from fashion icons (Sarah Jessica Parker) to iconic brides (Amal Alamuddin Clooney), from leading ladies of hip-hop (Nicki Minaj) to First Ladies of the United States (Jacqueline Kennedy all the way through to Michelle Obama). The secret to his broad and enduring appeal? "I have always thought that my role as a designer is to do the very best I can for a woman," de la Renta told 1stdibs in a 2010 profile.
And for de la Renta, doing the very best meant making a woman feel beautiful, glamorous and full of confidence, whether she was walking down the red carpet or a crowded city street. "You carry the clothes, the clothes don't carry you," he went on to say in our story.
A perennial favorite on 1stdibs, Oscar de la Renta designs evolved over the years, as the large selection of items below attests, but whether bolero or ball gown, vintage or current, the pieces exude elegant sophistication and enduring originality — much like the man himself.
About the Seller
Why Shop on 1stdibs?
Only Vetted, Professional Sellers
Buyer Protection Guaranteed
Fully Insured Global Deliveries


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New Products
High-Shear, High-Temperature Fiber-Filled Transfer Tapes
The transfer tapes are part of Adchem's range of bonding solutions used in automotive, construction, electronics and general industrial applications. Adchem's 7742-74 and 7745-74 durable transfer tapes, 2 and 5 mils respectively, consist of pressure-sensitive acrylic adhesive and provide excellent shear strengths at temperatures to 300 F, according to company officials. Fiber reinforcement provides stability when the tape is slit to widths as narrow as 1⁄8 in. Adchem's adhesive transfer tapes adhere to metals and plastics, including low-surface-energy substrates.
Adchem Corp.: 631/727-6000; www.adchem.com
See also: Adchem Corporation
Related Enterprise Zones: Coil Handling


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The 10 Best-Paying Jobs of 2014
Is college still worth it? If you want a sure path to making lots of money, yes.
Nearly all of 2014's best-paying jobs require an advanced degree, according to a new ranking from the job portal Careercast.com. Seven of the 10 most lucrative positions are in the health-care industry.
Topping the list this year is surgeon, with an average annual income of $233,150, according to CareerCast, which gathered data from the Bureau of Labor Statistics, trade associations and its own Jobs Rated report. General practice physicians, psychiatrists, orthodontists, dentists, pharmacists and podiatrists also appeared in the top 10.
"If your interest is in doing something you love and generating a high income, there's no question that you need a degree, and you need a graduate degree," said CareerCast publisher Tony Lee. "That's all there is to it."
Besides high incomes, this year's top 10 jobs have another thing going for them: high growth. Nine of 10 are projected to see the number of positions increase by double-digit percentages over the next eight years, according to the Jobs Rated report. The exception is air traffic controller, with a current average annual income of $122,530 and a projected growth rate of 1% by 2022.
After the jump, the 10 best-paying jobs of 2014 as rated by CareerCast.
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The LMX2541 is an ultra low-noise frequency synthesizer which integrates a high performance delta-sigma fractional N PLL, a VCO with fully integrated tank circuit, and an optional frequency divider. The PLL offers an unprecedented normalized noise floor of -225 dBc/Hz and can be operated with up to 104 MHz of phase-detector rate (comparison frequency) in both integer and fractional modes. The PLL can also be configured to work with an external VCO.
The LMX2541 integrates several low-noise, high precision LDOs and output driver matching network to provide higher supply noise immunity and more consistent performance, while reducing the number of external components. When combined with a high quality reference oscillator, the LMX2541 generates a very stable, ultra low-noise signal.
The LMX2541 is offered in a family of 6 devices with varying VCO frequency range from 1990 MHz up to 4 GHz. Using a flexible divider, the LMX2541 can generate frequencies as low as 31.6 MHz.
The LMX2541 is a monolithic integrated circuit, fabricated in a proprietary BiCMOS process. Device programming is facilitated using a three-wire MICROWIRE interface that can operate down to 1.6 volts. Supply voltage ranges from 3.15 V to 3.45 V. The LMX2541 is available in a 36-pin 6-mm × 6-mm × 0.8-mm WQFN Package.
|Part number
|Output frequency (Min) (MHz)
|Output frequency (Max) (MHz)
|Normalized PLL phase noise (dBc/Hz)
|1/f noise (10-kHz offset at 1-GHz carrier) (dBc/Hz)
|Current consumption (mA)
|Integrated VCO
|3.15 to 3.45


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text: If your employer's retirement plan doesn't offer a stable-value fund, consider one of these instead By Thomas M. Anderson, Contributing Editor October 1, 2009 Investors in stable-value funds want it both ways. They prefer the stability of a money-market fund with the higher returns of a bond fund. By buying insurance to guard against share-price declines, stable-value funds have, with a couple of minor exceptions (see Stable Funds in Chaotic Times), been able to keep customers happy. No wonder employer-sponsored retirement plans have more assets in stable-value funds than in any other category.Stable-value funds typically yield a couple of percentage points more than money-market funds. Currently, the average stable-value fund yields 3%, while the average taxable money fund yields 0.06% -- essentially nothing. Unfortunately, stable-value funds aren't available to everyone. About half of employer-sponsored retirement plans have a stable-value option, and you can find them on the investment menus of some 529 college-savings plans. Moreover, you can't buy a stable-value fund directly from a financial-services provider. If you don't have access to a stable-value fund, consider a high-quality bond fund instead. Many of them yield more than stable-value funds, which typically hold high-quality corporate bonds, rated single-A or better, that mature in two to five years. But regular bond funds can't guarantee the constant share-price value that makes stable-value funds so attractive to risk-averse investors. Advertisement Bond funds face two main kinds of risk. First, there's interest-rate risk. As rates rise, bond prices fall. You also have to be mindful of credit risk, the chance that a fund's holdings will default on their obligations. You can mitigate some of the risk by looking for well-managed funds that hold high-quality bonds and don't extend maturities very far. Here are three bond funds that make worthy substitutes for stable-value funds. Two are members of the Kiplinger 25, and one is an index fund. The average credit quality of all three funds is single-A or better. Managed by Bill Gross of bond powerhouse Pimco, Harbor Bond (symbol HABDX) has consistently topped its rivals. The fund, a member of the Kiplinger 25, has beaten the average intermediate taxable-bond fund nine out of the past ten years (including 2009 through August 31). Over the past ten years, it returned 7.2% annualized, outpacing its rivals by an average of two percentage points a year -- a huge discrepancy in the normally stodgy world of bonds. Gross and his team minimize risk by holding healthy doses of high-quality corporate bonds and cash. The fund, which yields 3.9%, would lose about 4.8% of its share price if interest rates rose one percentage point. Since its inception in late 1987, the fund's biggest one-year loss came in 1994, when it lost 3.8%. Harbor Bond earned 3.3% in last year's difficult market. Its annual expense ratio is a below-average 0.55%. Advertisement The nine managers at Dodge & Cox Income (DODIX) seek out bargains in the corporate-bond market, taking advantage of the kind of irrational selling that was so prevalent last year. Also a member of the Kiplinger 25, the fund earned 6.6% annualized over the past ten years. That beat the typical intermediate-bond fund by an average of one point a year. Dodge & Cox topped the category average eight years out of ten. The fund, which yields 5.5%, would fall about 3.9% if interest rates rose one percentage point. Like Harbor Bond, Dodge & Cox Income sustained its worst annual loss in 1994, losing 2.9%. In 2008, it lost 0.3%. The expense ratio is 0.4%, near rock bottom for an actively managed fund. Index funds are boring. And that's why a solid one, such as Vanguard Total Bond Market (VBMFX), makes a good alternative to a stable-value fund. Total Bond reliably tracks the Barclays Capital U.S. Aggregate Bond index, a broad benchmark of market performance for investment-grade bonds, and carries a low, 0.2% expense ratio. Total Bond, which yields 4.3%, returned an annualized 6.0% over the past ten years. The fund holds more than two-thirds of its portfolio in government bonds and mortgage-backed bonds guaranteed by government agencies. If interest rates rose one percentage point, Total Bond would see its share price decline by about 4.3%. Since its launch in 1986, the fund's worst year was 1994, when it lost 2.7%. Last year, it earned 4.6%. High-quality bond funds, as well as stable-value funds, are for storing your mattress money, not for getting rich. If you want higher returns, invest in stock funds.