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- Home
- About Us
- Our Services
- Wealth Management
- Business Insurance
- Financial Planning
- General Insurance
- Health Insurance
- Life Assurance
- Mortgages
- Equity Release
- Pensions
- Savings & Investments
- Taxation
Wealth, just like your health, must be carefully preserved. Your assets need to be protected against the potential threats of erosion by taxation, the effects of inflation and investment risks.Read More
Whatever your level of wealth, there is nothing wrong in making the decision to prepare a risk aversion strategy. Risk aversion is a reasonable and prudent strategy for anyone who is sure that they already have ample to provide for themselves and their family into the future.
There are plenty of ways of preserving wealth in real terms...
All businesses are exposed to risks in their day-to-day operations. Without business insurance cover to provide protection against some of these risks, businesses would find it difficult to operate efficiently and profitably.Read More
Adequate business insurance is therefore not a luxury - it is an absolute necessity.
These days, many people are not afraid to seek compensation. No win - no fee advertisements encourage claims, and businesses need to protect themselves against liability claims that could run into millions...
We all have goals, dreams, ambitions for the future, for ourselves and our families, but how do we achieve them?Read More
Professional Financial Planning is the process which aims to help you realise your ambitions - whatever they may be. As professional financial advisers we can help you make informed decisions about your financial future, short, medium and long term.
You will almost certainly have plans of one kind or another - buying a home, starting a family, living abroad...
This is an area of financial planning that is often overlooked. Traditionally, we have our buildings and contents insurance with our mortgage lenders, which may be uncompetitive in a very competitive marketplace. It may also be the case that a property may be underinsured, due to decoration, extension or the increase in house prices.Read More
In addition to home insurance, we can also provide access to cover for accident, sickness and unemployment.
General insurance is important for your peace of mind.
Health Insurance is probably one of the most important types of insurance you can own. Without it, an illness or accident can have serious long-term financial implications for you and your family.Read More
Most people will be aware that Health Insurance can cover the cost of private medical treatment for any acute conditions you may suffer in the future - from something as simple as a broken bone to more serious conditions like a heart attack or cancer.
However, there are a number of other types...
The main purpose of Life Assurance is to provide money for those people who may depend on you financially, in the event that something should happen to you. These people could include family members or business partners.Read More
It can provide the reassurance of financial protection for you, your family and your business associates.
A Life Assurance policy pays out a sum of money when the person who is covered by the plan dies. The money is intended to pay off any outstanding debts and support your dependants financially...
Your mortgage is probably the largest financial transaction and commitment you are likely to undertake. Surely then you should seek mortgage advice which is individually tailored to your needs and requirements?Read More
We are not tied to any particular lender, which means that we have the ability to act on your behalf in order to establish the most appropriate mortgage solution for you.
Since 2007 the Credit Crunch has had an effect on the number of mortgage providers available in the UK and has caused...
If you're over the age of 55, equity release offers you a way to use the value of your home to raise money.Read More
There is a range of equity release schemes available on the market offered by reputable equity release providers, and they fall into two main categories, Lifetime Mortgages and Home Reversion Plans.
Each type of equity release scheme facilitates a different method of releasing the equity in your home, and there are various other useful features available to create the ideal equity release scheme for you.
When you retire you still need food and shelter as an absolute minimum, but of course you will want to maintain the lifestyle to which you have become accustomed, so unless you can guarantee a large inheritance, you need to provide yourself with a secure income for the rest of your life.Read More
A well prepared pension plan which is regularly reviewed should go some way to providing you with a reasonable level of income in your retirement.
A pension plan requires action as soon as possible, so start now - and if you have already started, take the opportunity to have a closer look...
Often, people save for a specific reason and it's usually the safest way to build up a pot of money.Read More
It's less risky than investing, but it offers limited growth. The most you'll earn on the money you save is the interest added. Saving is perfect for people who don't want to take any risks with their money, and most savings accounts have easy access or are for a fixed term.
There are many different ways to save, but whichever way you choose, the general idea is the same: to build up some money - savings - that can be used, for example, to make a large purchase...
Most of us face being taxed on our income, our capital gains, and in some circumstances the value of our estate when we die.Read More
Taxation can be very complicated and the rules, reliefs and allowances often change, so it is worth obtaining a clear grasp of how these taxes work by discussing with a professional adviser the most efficient way to arrange your finances.
An expert will be able to help you plan your taxes in advance, and come up with effective strategies that will use the lawful reliefs and allowances to minimise the amount you have to pay.
- Testimonials
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Pensions & Capital
Pensions & raising capital
Directors may prefer to establish a separate pension plan from that of their employees. The reasons for this are that the term of their employment may be a fixed number of years, their tax position may be more complicated than other employees, or they may prefer to set up a form of self administered scheme more suitable to their circumstances.
Directors and partners may also wish to leverage their company pension scheme at some stage to raise funding for the business. This may be a more tax and cost efficient way of funding the acquisition of commercial property.
In these circumstances sound pension advice will be valuable.
Other Areas of Expertise
Wealth Management
Wealth, just like your health, must be carefully preserved. Your assets need toRead More...
Retirement Planning
When you retire you still need food and shelter as an absolute minimum, but of cRead More...
General Insurance
This is an area of financial planning that is often overlooked. Traditionally, wRead More...
Health Insurance
Health Insurance is probably one of the most important types of insurance you caRead More...
Life Assurance
The main purpose of Life Assurance is to provide money for those people who mayRead More...
Your mortgage is probably the largest financial transaction and commitment you aRead More...
Do you fancy the idea of living on a little over £115 per week when you retire?Read More...
Savings & Investmen..
Often, people save for a specific reason and it's usually the safest way to builRead More...
Most of us face being taxed on our income, our capital gains, and in some circumRead More...
Equity Release
There is a range of equity release schemes available on the market offered by reRead More...
Matrix Financial Limited is authorised and regulated by the Financial Conduct Authority.
Matrix Financial Limited is entered on the Financial Services Register (www.fca.org.uk/register) under reference 577053.
Registered in England and Wales under Company Number 7905019.
Registered office at Tofino House, 32 Newmarket Road, Cambridge CB5 8DT.
The FCA do not regulate National savings products, loans, Will writing and some forms of mortgage, offshore funds and inheritance tax planning.
The guidance and/or advice contained within the website is subject to the UK regulatory regime and is therefore targeted at consumers based in the UK.
If you wish to register a complaint, please contact us either in writing at: Matrix Financial Limited, Tofino House, 32 Newmarket Road, Cambridge, Cambridgeshire, CB5 8DT or by phone 01223 365340.
A summary of our internal complaints handling procedures is available on request and if you cannot settle your complaint with us, you may be entitled to refer it to the Financial Ombudsman Service at www.financial-ombudsman.org.uk or by contacting them on 0800 023 4567.
Client Testimonials
Christopher Murphy, Director, Physio UK Ltd, Epsom
I have had the pleasure of working with Kelvin and Matrix Financial for the past 5 years. My initial enquiry was with respect to investments and planning my retirement. Kelvin handled that seamlessly and has continued to update me, check in and make sure the plans I am in are working as best as possible. In addition, further requests regarding a new mortgage were dealt with in the same extremely efficient and friendly manner. There is never any chasing, it all just seems to magically happen, brilliant!
David LLB, London
I have been a client of Matrix Financial for many years now. They have provided me with expert financial planning and investment advice, helped with obtaining mortgages (both personal and buy-to-lets), and have arranged my affairs in the most tax efficient way. I have been working abroad for most of the last 25 years, and left my financial affairs to Matrix. I was most pleasantly surprised to return and find everything in order. Matrix has provided me with quick, friendly, efficient and effective service over the years, I have no hesitation in recommending them to others.
Gillian Trier, Yorkshire
I feel I have been extremely fortunate in having the benefit of the services of Kelvin, Matrix Financial, for around the past 22 years. Since my early days he has offered sound advice about planning finances to meet lifestyle choices, financial obligations and retirement funding. He has on three occasions advised on and progressed mortgage funding to suit my particular financial requirements for home extensions and one recent purchase. He continues to monitor my investments and advise on any advantageous or necessary changes from which I benefit both financially and through peace of mind.
TJ Salih Chartered Physiotherapist, Back2normal, London
I have used the services of Matrix Financial for over 10 years for mortgages, pension planning, protection and investments for myself and my family and have been amazed by the service that I have received; so much so that I recommend Matrix Financial to everyone I know who may need any financial services. Whenever I have a query, I receive a prompt reply via email or telephone, and often the query is answered immediately. I plan to continue to use Matrix Financial for the foreseeable future.
T.Webb, Dorset
Matrix financial have been my advisers for 11 years during which time I have found their dedication to providing sound financial advice and investment market awareness, excellent. I have been particularly pleased with the retirement planning where a guaranteed income route was recommended ensuring that, despite the recessionary times of 2008/09, my fund values achieved growth and my retirement income has been maintained.
P K Jones, Spain
I am expatriate, now resident in Spain, since 2000. Matrix Financial has provided investment advice and managed my portfolio successfully and appropriate to my risk levels, ensuring that my income levels have been maintained. Their regular review service is both important and valuable. I have recommended Kelvin and Matrix Financial to many of my friends and will contiue to do so.
Contact Us
Matrix Financial Limited
Cobble Yard
Email : Email Us


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2 more Polish plane victims buried in wrong graves
WARSAW, Poland (AP) — Forensic testing has proven that two more victims of the 2010 plane crash in Russia that killed Polish President Lech Kaczynski and 95 others were misidentified and buried in the wrong graves, Polish prosecutors said Wednesday.
The number of misidentified victims has now grown to six and highlights flaws in the handling of the crash's aftermath in Russia. Such errors are deepening Polish distrust of historic foe Russia, while also fueling Polish conspiracy theories about the cause of the disaster. But a Polish official also has been blamed for misidentifying one of the victims, while even the families of victims of the brutal crash have made mistakes in identifying their loved ones.
Capt. Marcin Maksjan, an official with the military prosecutors, said two bodies suspected of being in the wrong graves were exhumed from two separate locations in Warsaw last week, and that forensic testing confirmed the suspicions.
"The results show unequivocally that the bodies of the victims were laid to rest in the wrong graves," a separate statement by military prosecutors said. It said the genetic tests were carried out independently by two research centers.
Polish media have said they were two Roman Catholic priests, but authorities wouldn't confirm their identities.
The suspicions arose after a study of forensic medical documentation sent by Russia raised suspicions that errors had been made.
Maksjan said it appeared that families of the victims made a correct identification of their loved ones after the crash but that Russian officials probably then put them in the wrong coffins in a Moscow institute of forensic medicine where the bodies were handled before they were sent to Poland for burial.
Since September Polish authorities have also exhumed four other bodies and confirmed they were mixed-up. In one case, the Solidarity hero Anna Walentynowicz was found to have been confused with another female victim. Soon after that Poland's last president-in-exile, Ryszard Kaczorowski, was exhumed and reburied after being found to be in the wrong grave.
In Kaczorowski's case, a Polish Foreign Ministry official misidentified the body in Russia. He recently apologized for that mistake.
Authorities say more exhumations could take place.
The string of exhumations, repeat forensic testing and reburials has revived the pain of the 2010 tragedy, which killed not only the president and first lady but also dozens of the country's top civilian and military leaders.
An awareness that something was amiss in the identification of the bodies has also added to suspicions some Poles hold of Russian ill will, and they are feeding conspiracy theories that Russia caused the crash intentionally.
Most Poles, however, reject the conspiracies. A Polish state investigation found bad weather and human error to have caused the crash.
Russian officials have said that any mistakes in identifying the bodies resulted from the badly damaged state of the bodies after the impact of the crash.
Copyright 2012 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

subset: commoncrawl


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- This event has passed.
Strength Training
May 10, 2019 @ 9:30 am - 10:30 am
|Recurring Event (See all)
An event every week that begins at 9:30am on Friday, repeating until December 20, 2019
Event Navigation
AT ST. CATHERINE'S OF SIENA ($5 drop-in)
Sitting and standing, using weights, and having fun, participants work to strengthen and stretch their muscles. A good way to burn off some calories, build up your base for balance and health, and share the time with like minded people. Instructor: Deb Bosanko
$5 drop in or Lifelong members are eligible for $30/month unlimited Health and Wellness classes


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There's only one adjective to describe SVJ Roadster: unrivaled.
Produced in just 800 units, it is the most iconic model of the Aventador family, thanks to its aerodynamic lines that slice through the air, and its breathtaking design, the expression of the most refined Italian taste and craftsmanship.
Lamborghini aerodynamics are the most futuristic ever: the ALA 2.0 system and aero-vectoring ensure minimum drag on straightaways, and optimal aerodynamic load in cornering. The naturally-aspirated V12 engine, with its 770 CV, is the most powerful ever, capable of reaching more than 350 km/h at 8500 rpm, with braking from 100 to 0 km/h in just 31 meters.The interiors are entirely customizable, and the technology is designed to highlight the experience of record-breaking performance.
Driving at race car speeds, hitting 100 km/h in just 2.9 seconds, hearing the roar of the engine blend with the sound of the wind: these are the adrenaline-pumping experiences you can live aboard the Aventador SVJ Roadster.
Vibrant emotions are made possible by perfect aerodynamics, groundbreaking technology, and a futuristic aesthetic that makes no compromises. This makes the SVJ Roadster ideal for a performance that is nothing less than thrilling.
Sophistication, aggressiveness, lightness, and aeronautics-inspired aerodynamics. The beauty, power, and performance of the SVJ Roadster are guaranteed by ultra-light materials, such as carbon fiber, used for the body and the removable hardtop. The body features air intakes larger than any previous model, more extended side skirts, accentuated aerodynamic profiles, and a lighter and higher-mounted exhaust system.
The hardtop is made using an innovative high-pressure RTM technology that guarantees a product of superior workmanship and quality.
The hood, front fenders, and doors are also made of ultra-light materials, providing a significant reduction in the weight of the car, where every detail is never just an end in itself, and where the emotions are the expression of truly bold performance.
The technological look of carbon fiber – featured in the monocoque, which forms the cockpit and recurring in the doors, seats, central tunnel and console – coexists with a design of clear aeronautical inspiration, while the leather and Alcantara® upholstery add a boldly exclusive touch to the luxurious interiors.
Finally, the exquisite cross-stitching details and notable presence of the SVJ Roadster internal plate confer a truly unique character to this new gem of engineering and highly-refined aesthetics.
Each of the systems at work inside Lamborghini vehicles is a masterpiece of engineering and technology. And the Aventador SVJ Roadster incorporates all the best technologies ever developed by the company. The lateral vehicle dynamics is controlled by a steering system that acts on all four wheels via Lamborghini Dynamic Steering (LDS) and Lamborghini Rear-wheel Steering (LRS), aided by the use of active torque distribution between the front and rear axles (4WD) and aero torque vectoring (ALA). The vertical vehicle dynamics is managed by the Lamborghini Magneto-rheological suspension (LMS) and the active aerodynamics. Finally, the longitudinal dynamics relies on the four-wheel drive system (4WD), the integrated traction control and the new operative logics of the ABS. The LDVA 2.0 system combines all the information gathered through the car's inertial platform, and determines in real time the optimal settings for any driving condition. The result is perfect performance, absolutely safe and always compelling.
Aerodinamica Lamborghini Attiva 2.0
Lamborghini's patented ALA system has been developed to an enhanced level for the Aventador SVJ Roadster, now the ALA 2.0, including new optimized air inlet and aero channel designs. The system has been re-calibrated taking into account the enhanced vehicle's lateral accelerations.
The ALA system actively varies aero load to achieve high downforce or low drag, depending on dynamic conditions. Electronically-actuated motors open or close active flaps in the front splitter and on the engine bonnet that steer the air-flow, front and rear.
The new Aventador SVJ Roadster offers a unique combination of the active steering system (Lamborghini Dynamic Steering) and the rear steering system (Lamborghini Rear-wheel Steering), ensuring top-of-the-line dynamic performance.
The LDS system adapts to the speed and the selected driving mode, moving between direct steering and a more indirect mode, while the LRS system manages the rear steering axle by means of two electromechanical actuators. Thanks to this system, at low speeds the rear axle steers in the opposite direction of the front axle, generating a virtual reduction of the wheelbase that translates into greater agility and unrivaled performance around corners. At high speed, instead, the two axles rotate in parallel, resulting in a virtual increase of the wheelbase, to ensure full control of the vehicle and excellent stability.
The new Aventador SVJ Roadster features magneto-rheological front and rear shock absorbers with pushrod system, which constantly modify the behavior of the suspensions according to the road conditions and the driving mode selected. In addition to compensating for roll and undesired movements of the vehicle's body, the system was designed specifically to work in concert with the Rear-wheel Steering, thus ensuring a perfect response in any type of condition and allowing ALA to maximize efficiency and downforce, maintaining a constant aerodynamic flow between the bottom of the vehicle and the ground.
The four-wheel drive system of the new Aventador SVJ Roadster was specifically optimized to work together with all the new active systems, in particular Rear-wheel Steering, whose stabilizing effect allows a high percentage of torque to be distributed to the rear wheels. This produces a sportier and more engaging experience at the wheel, without compromising on safety or ease of driving. Working in symbiosis with the car's other active systems, the four-wheel drive system allows for excellent performance and supreme driving pleasure even in situations involving poor grip. The torque distribution between the front and rear axles varies dynamically, in real time, depending on driving conditions, grip as well as the selected driving mode. Moreover, Aventador SVJ Roadster can count on a new generation of Pirelli PZero Corsa tires, conceived to take full advantage of the car's innovative systems thanks to improved grip and outstanding consistency, thus ensuring superior driving dynamics.
No matter what driving conditions you find yourself in, the new Aventador SVJ Roadster gives you full control thanks to the dynamic mode selector, which lets you optimize engine, transmission, drive, steering, suspensions, and stability control settings by choosing between STRADA, SPORT, CORSA and EGO MODE. This last option allows full customization of every individual setting, for the most personal driving experience ever achieved. By uncoupling the longitudinal, lateral and vertical dynamics, EGO mode makes it possible to obtain the vehicle's top performance at all times and in any condition.
The indomitable V12 engine of Aventador SVJ Roadster stands out for its exceptional design and the advanced technology of its materials. Boasting 770 CV at 8,500 RPMs, and capable of accelerating from 0-100 km/h in 2.98 seconds, Aventador SVJ Roadster provides thrills unlike anything that has ever been experienced before.
The ISR (Independent Shifting Rods) transmission ensures amazingly fast and exciting gear shifts. The design goal was simple: to create an extremely fast robotized transmission, capable of generating unique driving thrills. The ISR gearbox also offers two crucial advantages for the realization of a super sports car: extremely low weight and a size even smaller than a manual gearbox.
The use of carbon fiber and its derivatives is among the characteristics that give the Aventador SVJ Roadster, entirely manufactured at Lamborghini's plant in Sant'Agata Bolognese, its phenomenal driving precision. The monocoque of the Aventador SVJ Roadster offers incredible weight reductions and, at the same time, unprecedented rigidity.
Extreme personalization, capable of rendering the SVJ Roadster a timeless, one-of-a-kind vehicle.
Exclusivity has always been embedded in the Lamborghini spirit, because the luxury of endless possibilities is not for everyone.
The Ad Personam program makes such luxury an inherent feature of the new Lamborghini SVJ Roadster, which was designed to grant any wish of personalization down to the slightest of details.
From the colors and leathers to the stitchings and upholstery, every element can be customized to make the car literally unique.


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Nationals stuck in neutral vs. Wainwright, Cards
Defense commits four errors, while offense musters just two hits
WASHINGTON -- The Nationals are off to a slow start when it comes to proving they belong in the same league as the Cardinals.
Washington had a tough time catching the baseball on Thursday night in an 8-0 loss at Nationals Park. The Nationals have lost eight consecutive games to the Cardinals, dating back to Game 5 of the 2012 National League Division Series.
What made this loss even worse was that the Nationals made four errors, two of them by shortstop Ian Desmond. And that doesn't account for the misplays that were ruled hits. In the first inning, for example, Nationals right-hander Taylor Jordan misplayed a ball off the bat of Kolten Wong that was ruled a hit. Jordan had a tough time getting the ball out of his glove and Wong beat Jordan's throw to first.
After the game, manager Matt Williams had a closed door meeting with his players. When it was time to talk to reporters, Williams was clearly upset, but declined to reveal what he said to his players.
"That's for me and my team." Williams said. "I seem very upset? I'm just not answering that question. That's for me and my team, and nobody else's business. Regarding the game, it was probably the worst one we played."
Catcher Jose Lobaton confirmed that Williams was upset after the game.
"Not only him, I think everybody," Lobaton said. "It's all in everybody's faces. We are a little down. We know that we played pretty bad. We are professionals and we have to get ready for tomorrow."
The offense was stymied by Adam Wainwright, who pitched a two-hit shutout. The only time the Nationals had a legitimate chance to score was in the second inning. They had runners on first and second and no outs, but Danny Espinosa flied out and Nate McLouth grounded out. After Lobaton was walked intentionally, Jordan struck out looking.
"He has four pitches that [he] can throw at any time in any count," catcher Yadier Molina said. "We can go with a curveball, we can go with a cutter. It's so good that he can do that. Anytime you see a guy who can throw four pitches for strikes, it's tough to hit. And that's what he showed tonight."
Said Williams: "[Wainwright] throws two kinds of fastballs and spots it well. He threw a lot of curveballs tonight. He has the ability to reach back when he needs to and throw at 94 [miles per hour]. He is a pretty special pitcher."
It was Desmond's error in the first inning that helped St. Louis score three runs. With runners on first and second, no outs, and Jordan on the mound, Matt Holliday doubled down the third-base line scoring Matt Carpenter, who reached base on the error by Desmond. Desmond leads the Major Leagues in errors with seven. He is looking like the player who made a lot of errors in 2010 and '11.
"The first ball of the game, I booted. I set the tone. If I want to be captain of this team, and I do, I have to be better than that," Desmond said. "I've been in some dark places defensively and this is right there with them."
Matt Adams followed Holliday and grounded out to second baseman Espinosa, but Wong scored on the play. Molina then followed with a single to left field, scoring Holliday to make it 3-0.
The Cardinals scored their fourth run three innings later. Wainwright hit a ground ball to Desmond, who threw to Espinosa for the force at second, but Espinosa dropped the ball and Peralta scored on the play.
"We verified with our guys, it looked like [Espinosa] didn't have a lot of control," Williams said. "It was a tough throw down and away from him, trying to turn two and trying to get two out of it."
Jordan lasted 5 1/3 innings, allowing seven runs -- five earned -- and striking out four batters.
St. Louis scored four additional runs by the seventh inning. Adams highlighted the scoring with a two-run single in the sixth inning off of Blake Treinen.
So how do you fix the defense? Williams said the Nationals will continue to work hard before games to make things right.
"We'll keep grinding away at it," Williams said. "We will go out there tomorrow and we'll certainly take a full [batting practice], full grounders. It is scheduled to be extra work for the pitchers tomorrow. It's part of the schedule. ... We do it all the time. What to make of [the bad defense]? I don't know."


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Hanggang Sa Dulo Ng Buhay Ko August 19 2019
SHOW DESCRIPTION: Yvie (Megan Young) and Matteo (Rayver Cruz) are childhood sweethearts who fell in love and married each other. Together with their adopted son, they happily moved into their new family home, along with Yvie's best friend and cousin, Katya (Kim Domingo). But their bliss is quickly replaced by fear. Naomi (Kris Bernal), Matteo's ex-girlfriend, will stop at nothing to disrupt their perfect lives—dead or alive.


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Some of the major consumer outreach strategies behind Go RVing's new "Away" national advertising campaign will be examined during an all-attendee session at the RV Dealers International Convention/Expo Oct. 1-5, in Las Vegas.
Dealers will learn about the consumer research behind "Away" and its sophisticated methods for reaching consumers based on what people say they're looking for right now in leisure, vacation and personal travel, according to a news release.
"Go RVing: Research-based Strategies to Motivate Today's RV Buyers," is a special General Session scheduled for Thursday, Oct. 4, from 8 a.m. – 9:30 a.m.
"This will be an excellent opportunity for dealers to get a detailed look at some consumer outreach initiatives that are included in the new Go RVing "Away" campaign and how some of these ideas can help reach new customers in local markets," said RVDA President Phil Ingrassia, one of the speakers on the panel.
In addition to reviewing some of the latest consumer research, panelists will discuss how public relations, mobile apps, and social media fit into this multi-media consumer outreach program. The Richards Group developed the campaign in collaboration with industry representatives on the Go RVing Coalition.
In addition to Ingrassia, the session also features Chris Mahony, executive director of Go RVing Canada; James Ashurst, vice president of public relations and advertising for RVIA; and Chad Strohl, account manager for The Richards Group.
The RV Dealers International Convention/Expo will be held Oct. 1-5, at the Rio All-Suite Hotel & Casino. The convention is sponsored by RVDA–The National RV Dealers Association, RVDA of Canada and the RV Learning Center.
The 2012 convention will feature an exhibit hall filled with the RV industry's top suppliers offering products and services to help dealers improve profitability. RVDA's Partners in Progress Brand Committees will also meet to work on important dealer/manufacturer issues.
Companies interested in sponsorship opportunities and exhibitor information can contact RVDA at (703) 591-7130 or send an e-mail to [email protected] To register and for more information on the Convention/Expo, visit www.rvda.org.


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Men's Vintage Checked Flannel Shirt - Large
£20.00 £16.00
Men's vintage checked flannel shirt - Red and blue colourway.
+ Size label states: Large
+ Measurements (inches) : Pit to pit = 21, body length = 30, sleeve length = 22
Model: 5"10 / Medium build.
Please note that all vintage items have been previously worn, and may show some signs of previous wear. However, any significant damage will be photographed in the items listing.
Royal Mail 48 Hour (2-3 Working Days) - £2.99
Royal Mail 24 Hour (1-2 Working Days) - £4.99
Royal Mail International Tracked & Signed (up to 7 Working Days) - £9.99
Royal Mail International Tracked (up to 8 Working Days) - £11.99
All orders are despatched within 1-2 working days after payment confirmation.
All items can be returned and issued with a refund. You have 14 days from receiving your item, to send back any full price items for a refund or exchange (21 days for international orders). Items received back after the 14 day period will not be eligible for a refund, and there will be a charge for returning the goods to the sender.
For more information, please visit our Returns Policy.


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Welcome to Reid and Rhea Dentistry
We know a healthy and beautiful smile is important; at Reid and Rhea Dentistry, Dr. Shirley Reid and Dr. Randy Rhea provide personalized dental care for our patients with an emphasis on prevention and education. Our goal is to provide the highest quality dental care in a comfortable, compassionate manner to those who recognize the value of their teeth and their smile.
We are dedicated to educating our patients on the benefits of keeping their mouths healthy, and committed to providing the most aesthetic, state-of-the-art care in a modern and safe environment. Our affordable services include most aspects of general family dentistry, cosmetic dentistry, periodontal treatments, teeth whitening, and snoring prevention.
Our staff is concerned about your needs, wants, and desires. We are happy to serve you in any way we can to make your visit as pleasant as possible. Please feel free to contact our Little Rock dental office to schedule an appointment today!


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How much is a boot camp?
The cost of fitness boot camps depends on how often you go, the package you are purchasing (or if you are paying a drop-in fee), the location of the bootcamp, the equipment the instructors provide, and the background and reputation of the instructor. Smaller towns and areas with a lower cost of living typically have lower rates for boot camp services than big cities and regions with a higher cost of living. If you're paying per class on a drop-in basis, expect to pay anywhere from $12 to $25 or more, depending on the region and the instructor. When you purchase a package of classes, typically the more you buy at one time, the cheaper each class is. The same boot camp class might be $20 for a drop-in student, $15 for a student who pays for 10 classes per month, and $10 for a student who pays for 30 classes a month. Studio space can also affect costs, so if your boot camp takes place in a high-end gym with top-of-the-line equipment, the prices will likely be higher than a class that meets in an outdoor space with limited or no equipment. Shop around to find the right type of boot camp class and the right instructor for you.
What do you need for kickboxing?
What you need to bring to kickboxing depends on where you are working out and what your goals are. For a gym or fitness club's cardio-based group kickboxing class that does not use punching bags, you generally need only appropriate workout gear and enough water. For kickboxers who are training in a martial arts studio, working one-on-one with a trainer toward a specific goal or sparring with competitors, you will need your own boxing gloves (12- to 16-ounce gloves provide more protection for beginners) and hand wraps (to protect and support your hands under the gloves, as well as keep them dry). If your lessons are in a martial arts studio, you may not be permitted to wear shoes, so bring clean socks if you don't like to go barefoot. If your training includes sparring, you may be required to wear a mouthguard and/or protective headgear. Whether you're in a group fitness class or hardcore training session, bring a sweat towel for your comfort and the comfort of people around you.
What is kickboxing?
Kickboxing is a type of martial art whose basic moves are widely practiced in personal and group fitness regimens. In combat kickboxing, two competitors fight using four points of contact — both hands and both feet — unlike traditional boxing, where competitors are allowed to use their hands. In competitive kickboxing, opponents must remain standing, and no fighting can occur on the mat or ground. Kickboxing has its roots in Muay Thai and other ancient martial arts. Some elemental moves from kickboxing include roundhouse kicks, back kicks, hooks, uppercuts and more.
Modern group fitness kickboxing is practiced in gyms and workout studios across the country. It draws its moves from combat kickboxing, but instead of fighting with an opponent, participants perform jabs, crosses, punches and kicks in instructor-led, choreographed routines set to music. Personal trainers also incorporate kickboxing moves into workout routines, spending time punching and kicking the bag. These strength-building moves, mixed with high-intensity intervals, boost heart rate and increase strength.
Is kickboxing good exercise?
Kickboxing is great exercise. It works your whole body and really gets your heart pounding. Kickboxing combines upper- and lower-body movements like roundhouse kicks and uppercut punches that boost calorie burning. The type of kickboxing you do will determine how much exercise you get. Kickboxing training that takes place in a martial arts studio will involve kicking and punching a sandbag or sparring with a competitor, both of which will sharply increase the amount of exercise you'll experience in a kickboxing session. Comparatively, a study by the American Council on Exercise (ACE) found that women doing group fitness cardio kickboxing burned between 6.45 and 8.3 calories per minute, or approximately 350-450 calories burned during an hour-long class. This is roughly what you can expect to burn with jogging or similar exercise, but ACE says that cardio kickboxing offers the added benefits of increased strength and flexibility, sharper reflexes, and improved coordination. Whether you're training to fight competitively, learning kickboxing as a form of self-defense, or taking cardio kickboxing at your local gym, you'll get a full-body workout with positive health benefits.
Is kickboxing hard?
Kickboxing is as intense a workout as you want it to be. As with any fitness regimen, the more effort you put in, the more results you will get. The type of kickboxing you do will determine how physically challenging it is. Combat or self-defense kickboxing, where you train in a martial arts studio with sandbags or spar against combat partners, can be an intense physical workout. Group kickboxing classes that use sandbags as part of the workout will also elevate the degree of intensity, because of the level of exertion punching and kicking the bag requires. Cardio kickboxing group fitness, which employ kicking and punching moves but no sandbags, has comparable intensity to jogging but works a wider range of muscles while increasing strength, flexibility and coordination. Here are some of the core kickboxing moves:
- Cross: A straight punch that you throw slightly across your body, using your dominant hand.
- Jab: A quick, straight, face punch. Usually thrown with the non-dominant hand.
- Uppercut: A punch thrown up from the midsection (using either hand) that connects with the underside of your opponent's chin.
- Hook: A curved punch (using either hand) that connects with your competitor's jaw or chin.
- Side kick: A kick delivered when your competitor is at an angle to you. Raise your leg to the side, then bend at the knee to deliver the kick.
- Front kick: A kick delivered straight on while you are facing your opponent.
- Roundhouse kick: A kick delivered by swinging a leg up in a clockwise or counterclockwise motion (depending on which leg you're using) with momentum to strike the opponent with the instep of the foot.


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Lung Cancer is the leading cause of cancer-related death in both men and women, and it is notoriously difficult to treat, but as research studies are showing, there are promising new treatments on the horizon. Our expert guest, Dr. Heather Wakelee, leads one such study testing new treatments for early stage lung cancer.
Dr. Wakelee is assistant professor of medicine in the Division of Oncology at Stanford University and a member of the Stanford Cancer Center, where she is the co-leader of the lung cancer disease management group. In this interview, Dr. Wakelee discusses advances in lung cancer research over the last five years and why she is excited about the future of treatment for early stage lung cancer.
Why Is Lung Cancer So Difficult to Find and Treat?
Dr. Wakelee:
I think one of the most important reasons that lung cancer is difficult to treat is that we are not yet very good at finding the disease when it's in an early stage, so most people are diagnosed after the cancer has already spread and is not curable. Also, in people where it is found early, even when the disease has been removed completely with surgery, the chance of it coming back is much higher in lung cancer than in many other types of cancer. And, finally, many of the treatments that we have such as chemotherapy, for reasons that we don't completely understand, are not as effective in lung cancer as they are in other cancers.
It might also be that we often don't have any symptoms until the cancer has gotten to be quite advanced. We don't have pain receptors in the lung that would tell us if something unusual is growing there. And we can't feel our lungs the way someone would, say, detect a breast cancer. So that might be part of it.
Types and Stages of Lung Cancer
Dr. Wakelee:
We tend to group lung cancer into two big groups. The first, which is actually the least common, is called small-cell lung cancer, and that's somewhere between 15 and 20 percent of all lung cancers. It's called small cell because that's how the cells look under the microscope, and that disease tends to be more aggressive in that it's almost never treated with surgery. Usually at the time it's found, it has either spread throughout the lungs or throughout the body, and we treat that with chemotherapy and radiation.
The other and much more common type of lung cancer we call non-small-cell lung cancer, again in contrast to the small cell. And within non-small cell lung cancer, there are these major groups: There is adenocarcinoma, which is the most common; squamous cell carcinoma; large cell carcinoma; and then an "other" category. Knowing the differences between those is becoming more important because some of our new treatments actually work differently in the different types of lung cancer.
About a third of patients are diagnosed in what we call early stage disease, and "early stage" means that it's a mass that's just in the lungs or a mass that's in the lung and has spread to some lymph nodes that are also in the lungs. In that situation, surgery is the most important part of treatment.
Another approximately one-third or so of patients have the disease where it's called "locally advanced," meaning that it has spread into the lymph nodes that are in the center part of the chest known as the mediastinum. When that happens, surgery alone isn't quite as helpful. It can be a part of treatment for some patients, but people in that situation need to have chemotherapy and usually radiation as well.
Close to 40 percent of patients are found [at the time of initial diagnosis] with advanced stage or stage IV disease, where it has spread either significantly throughout both lungs or outside of the lungs. In that situation, we talk mostly about systemic treatments like chemotherapy.
So with the numbers, stage I is a small mass that hasn't gone to any lymph nodes, stage II is in the lymph nodes in the lungs, stage III is in the lymph nodes in the mediastinum, and then stage IV is more distant spread.
Hope for Better Screening for Lung Cancer in the Future
Dr. Wakelee:
Screening methods have been an ongoing problem for a long time with lung cancer. Years ago, we were hopeful that by getting chest X-rays on a regular basis for people at high risk, such as those who were heavy smokers, we might be able to find the disease earlier. Or perhaps by having people cough up sputum, we could look in the sputum and find cancer cells and hopefully diagnose it earlier. Unfortunately when [clinical] trials were done looking at those techniques, there wasn't an overall improvement in survival between the groups that were getting more extensive screening and those that were not, and so those efforts were abandoned. Now we have CAT (computed axial tomography) scans, or CT scans, and there have been ongoing tests looking at getting CT scans on a regular basis for people who are at high risk of lung cancer.
There is controversy in that area right now. There was one trial known as the I-ELCAP (International Early Lung Cancer Action Program) study, which was published in the New England Journal of Medicine, which hinted that there was a benefit from CT screening in the group of patients that they studied, but there were some problems with the methodologies used in that study. There is another trial that has just completed enrollment that was sponsored by the National Cancer Institute. We don't know any information from that study yet. Hopefully in 2009 we will have some early results.
I think everyone who treats lung cancer patients is very, very hopeful that we will end up having a way of screening or finding the disease earlier. Where the controversy lies is in whether the CT screening is going to be enough. We are all hoping that maybe we will have blood tests that will help us also, and there is also the problem that we don't know who to screen. Most of the work has been focused on people with a history of heavy smoking, and that's certainly the biggest risk for lung cancer. But probably about 20 percent of women who get lung cancer have never smoked, and around 10 percent of men. So that's a substantial number of people who are at risk for lung cancer and would never be included in the screening. So that's another problem.
Surgery Plus Chemo for Early Stage Lung Cancer: A Cure for Some?
Dr. Wakelee:
Treatment for non-small cell lung cancer depends on stage. Patients with stage I and II cancers, the cancers that are still in the lungs, are mostly treated with surgery. And now additionally some of them get chemotherapy. Patients who have stage III lung cancer usually get some combination of chemotherapy, radiation and sometimes surgery. And people with the metastatic or stage IV lung cancer are treated mostly with the systemic treatment such as chemotherapy as well as some newer drugs, what we call targeted therapy. Those new targeted drugs work a little bit different than chemotherapy, but are also treatments that are either given by vein or as pills.
The biggest change in treatment recently was the introduction of chemotherapy after surgery, what we call adjuvant chemotherapy. That's something that we have known is helpful for many years for colon cancer and breast cancer, and everyone assumed it would help in lung cancer, but we really didn't have any good data from clinical trials until just the last few years. Several trials in the last five years have shown that by giving chemotherapy after surgery we were able to cure more people from their lung cancer. The first trial that came out was in 2003, and then in 2004 we had more trials and in 2005 another big study, all finally showing that by giving chemotherapy you could cure more people. That was really the biggest change.
Again, these results were for patients with early stage disease. Surgery alone, for patients who only have the cancer in the lung itself, can cure up to 70, maybe even 80 percent of patients who have really small tumors. Once the lymph nodes are involved, those cure rates drop down to maybe 50 to 60 percent [for surgery alone], depending on the size of the tumor and how many lymph nodes are involved. So we have a long way to go. It's very different than the cure rates of surgery alone for many breast cancers, say, as a comparison. The hope was that by adding the chemotherapy we could improve those cure rates.
What Other Factors Influence Lung Cancer Treatment Success?
Dr. Wakelee:
There are many factors that go into the decision of which patients should receive adjuvant chemotherapy. Part of it has to do with the tumor itself. With the studies that have been done so far, we know that chemotherapy is definitely helpful for patients who have what we call stage II, where the cancer has gone into lymph nodes within the lung. We know that it is also helpful for patients who have stage III lung cancer who had surgery. Sometimes we don't know that the lymph nodes in the center part of the chest, the mediastinum, have cancer in them until the surgery happens. And if that's found at the time of surgery, we know those patients are definitely helped with chemotherapy as well.
We don't know if patients with stage I lung cancer, the ones who don't have any lymph nodes involved, are helped as much with the chemotherapy. Perhaps patients with larger tumors are helped, but that is an area where some of the [clinical] trials have shown benefit, others have not. It has depended somewhat on the size of the tumor as well. So that's the tumor part.
And then the patients obviously factor into it considerably. People who recover very well from surgery clearly are going to be able to tolerate chemotherapy much better than people who have a long recovery time. So generally if someone has recovered pretty well within a month or two, that's someone we would consider offering chemotherapy. And if someone is still really having a hard time after two months, that's someone who is probably potentially going to be more harmed than helped by chemotherapy.
We also look at what other medical problems someone has. Age can also be a factor. Though in at least one of the trials that was recently reported, and it was strongly in favor of adjuvant chemotherapy, they defined older patients as those over age 65 and found that they had as much benefit as the younger patients. So it's not just the age though age can be an indication in some people of their other health status. I think for people who are over the age of 80, most would be pretty cautious about offering chemotherapy unless it's someone who is still jogging every day. But for people in their 70s, most who have lung cancer who are able to have a surgery are also going to be fit enough to tolerate chemotherapy.
Using More Than One Chemotherapy Drug to Treat Lung Cancer
Dr. Wakelee:
We tend to start chemotherapy about a month or two after the surgery has been completed and patients have had time to recover. Sometimes that's extended out to maybe three months after surgery, but further than that we don't know how much the chemotherapy might help. So that's the window. The treatments themselves last about three months. Most of the treatment is given one day intravenously every three weeks for a total of about four treatment cycles, so that ends up being about 12 weeks total.
Normally, one chemotherapy drug can work okay. But with lung cancer we know from patients who have advanced-stage disease that a combination of two drugs is better than one. And when you add a third traditional chemo drug, at least in advanced-stage lung cancer, that just adds side effects without improving the likelihood of it working. Now, that's different in different diseases, but in lung cancer it's specific.
Side Effects That Patients Can Expect with Chemotherapy
Dr. Wakelee:
Almost always in adjuvant (post-surgery) treatment, in the early stage, we use a drug called cisplatin (Platinol), and that's a chemotherapy drug that's been around for a long time that works right at the level of the DNA [deoxyribonucleic acid, the cell's genetic material]. It's often given in combination with a second drug, and there are several that have been used. The most common one used in adjuvant treatment is called vinorelbine (Navelbine), and that's a drug that's given also intravenously. They are both given together on the first day. The vinorelbine has to be given a little bit more frequently, so it's also given one week later.
Other drugs that we are looking at because we use them a lot in the metastatic setting are the taxanes, such as paclitaxel (Taxol) and docetaxel (Taxotere), and there is also a drug called gemcitabine (Gemzar). Again, those are all traditional chemotherapy drugs that at different levels work on DNA, though the taxanes are a little bit different in how they work, but it does get back down to the DNA.
The biggest side effect with all chemotherapy drugs, the traditional chemotherapy drugs, affects the bone marrow, which means that the levels of the white blood cells that usually fight infections go down. The red blood cells can also go down, making people anemic. The platelets, which are involved in clotting of blood, can also go down a little bit. And those effects all are what we call transient, meaning that they will happen for a week or so after the chemotherapy, and then it gets better on its own. Those are things that we can follow closely and usually treat pretty well. There are some drugs that can be given to counteract that as needed as well.
Chemotherapy also certainly has a reputation for causing nausea and vomiting, and those side effects are certainly a possibility. But very good drugs have been developed in the last few years to combat nausea and vomiting, so that's rarely as much of a problem as it has been in the past.
The cisplatin can affect the kidneys, and so we have to monitor kidney function and make sure people get a lot of fluids. But with doing that, we're usually pretty safe there. There are also effects on the nerves, what we call neuropathy - numbness and tingling in the hands and feet. Usually that also gets better though sometimes it does not completely get better after chemotherapy, and those are things that we look for as well. And then there are a handful of other problems that can happen that are much less common.
As someone is going through chemotherapy, we watch them very closely. We see people back at least every three weeks and talk about side effects and make adjustments as needed in the dosing if we need to do that.
Clinical Trial Aims to Prove Cancer Growth Can Be Blocked
Dr. Wakelee:
The way that we are able to move forward in treating lung cancer, really any cancer, is by doing clinical trials. And most of the trials are designed to look at how we move from what we know works, the standard of care, to the next level. So when I talk to my patients in clinic, I always talk to them about the fact that until five years ago we didn't know to even give chemotherapy at all in patients who had had their lung cancer removed until we had trials where people got chemotherapy or did not, and from that we learned that chemotherapy was helpful. Now that we know that the chemotherapy is helpful, all of the ongoing trials offer chemotherapy to everybody but now offer additional drugs to some patients on the trial, trying to see if the additional drugs can add to the chemotherapy.
The trial that I am running is looking at a drug known as bevacizumab. The trade name is Avastin, and that drug is an antibody. Antibodies are also given by vein, just like most of the chemotherapy. This antibody blocks what's known as VEGF, or vascular endothelial growth factor, and VEGF is a very important molecule in developing new blood vessels. How does that relate to cancer? Well, all cancer cells, in order for a tumor to grow to any particular size, have to get blood vessels to come into them. And so if you are able to block those new blood vessels from forming, that will block the cancer from growing.
In patients with metastatic lung cancer, we know that adding the bevacizumab to chemotherapy makes the chemotherapy work better. In that setting, it might work a little bit differently than actually blocking the blood vessel growth, but nonetheless we definitely know that it has worked in several trials. It increases the chances of the tumor shrinking, increases the time before the cancer starts to grow again and actually improved survival in at least one of big trials. So with that knowledge, it made sense to take bevacizumab and see if we could cure more people with it by bringing it into the early stage treatment setting, where patients have already had their cancers removed, many of them are cured, but we still need to improve those cure rates.
So in the trial I am running, everybody who enters the trial gets the standard chemotherapy we have been talking about with that cisplatin drug, and either vinorelbine or docetaxel or gemcitabine, and then half the patients on the trial also get bevacizumab.
How Biologic Treatments Stop 'Bad Behavior' of Cancer Cells
Dr. Wakelee:
Biologics differ from the traditional chemotherapy in that they are going after a different target that makes the cancer cell behave in a way we don't like. The traditional chemotherapies all focus on the making of new DNA, and if you block it, then the cancer cells die. The new biologics focus on something else that makes the cancer cell behave poorly, as I mentioned. Bevacizumab (Avastin) works at the level of the blood vessels. If we can block blood vessels from forming, that's going to make a tumor mass shrink and help the chemotherapy work better.
Some of the other new targeted agents such as erlotinib, commonly called Tarceva, work at the level of different proteins that are on the surface of cells, particularly cancer cells. That drug, erlotinib, goes after what's called the epidermal growth factor receptor or EGFR, and there are other agents that target that. There are also hundreds of new compounds being developed that focus on other proteins that are either more common in cancer cells or only seen in cancer cells. And therefore if you can block them, you are more likely to attack the cancer cell and not harm as many normal cells.
In this study, we are using bevacizumab because it was the first drug that was shown to really add to chemotherapy in metastatic disease. There had been dozens of trials looking at chemotherapy with or without new drug X, Y or Z, and up until bevacizumab none of them had shown an improvement in survival versus the chemotherapy by itself. So when the study came out showing that bevacizumab was able to improve survival when added to chemotherapy for patients with metastatic disease - not curing, but helping people live longer - it made sense to then take that drug and bring it into the early stage disease where we were hoping we could cure more people.
Additionally, because of how the drug works by blocking blood vessel growth, the hope is that it's going to work even better in the situation where you have just a few floating tumor cells that escaped at the time of surgery or before the surgery and are hanging out in the body. If we can stop them from growing and pulling in blood vessels to divide and then become a big tumor mass, then hopefully we will be able to cure more people that way.
Mixed Results on Biologics Depending on the Lung Cancer Stage
Dr. Wakelee:
We don't have a lot of data yet on biologics for treating early stage lung cancer. The closest we have is a trial in patients with stage III disease who had the involvement in the center part of the chest, the mediastinum. Those patients were treated with chemotherapy and radiation, and then half of them got a biologic known as gefitinib (Iressa), which is similar to erlotinib, and half of them got just a placebo pill. And in that study, for reasons we don't understand, the patients getting the gefitinib didn't do as well as those who weren't getting it. So that certainly is a word of caution and another reminder of why it's so important for us to do the clinical trials. We can't assume something is going to work in a different stage of disease just because we know it works in metastatic disease.
However, I am very, very hopeful that the treatments that we are looking at with bevacizumab, a vaccine trial being looked at in early stage disease and an ongoing adjuvant trial with erlotinib will all hold promise. I am obviously biased towards the bevacizumab, but I think that there is a lot of room for hope that with those we will be able to improve cure rates even further.
Participating in Clinical Trials for Early Stage Lung Cancer
Dr. Wakelee:
Our study is open to anybody who has a lung cancer that has been completely removed with surgery. It's very important that we know the stage of the patient, which means that if a patient is looking at having a surgery, they need to check with the surgeons that the lymph nodes that are in that mediastinum are sampled at the time of surgery, because that helps us know what stage they are.
So anybody who has a stage I, II or III lung cancer, is eligible for the trial assuming that they are otherwise in good shape. People who have significant heart disease, we don't allow on the trial because if you think about it, the bevacizumab works by blocking blood vessel formation. If you have heart problems, you probably need a little bit more blood vessel formation, especially around the heart. We don't want to put people at risk. Also, in anyone with history of a stroke, there is the same potential concern. We don't want to put anybody on trial that's going to be at higher risk because they have a history of a stroke. But otherwise patients with stage I tumors that are at least four centimeters in size - and that is because of the earlier studies showing that we weren't helping the patients with smaller tumors as much - and anybody with stage II and stage III-A lung cancer.
It's always best to talk to your doctor, and that can be talking to the surgeon but almost everybody with a resected lung cancer should meet with a medical oncologist. They might choose not to get treatment at all, but at least talk with the people who actually give the treatment to learn more about it. Most physicians in this country are aware of this trial. We have close to 700 sites throughout the country that are open to enrollment for patients. There is a lot of information available on a Web site run by the National Cancer Institute, called clinicaltrials.gov. To look up our particular trial, search for the name of the study, E1505.
The Benefits and Risks of Participating in a Clinical Trial
Dr. Wakelee:
The benefits of participating in trials are the ability to have access to drugs that might not be available any other way. Also, the patients on clinical trials are watched a little bit more closely. And in addition to your doctor and the nurses, you also have the people who are working on the trial helping you, which can be a very good thing. I think that the importance of feeling like you are actually focusing on helping yourself but are doing something to help others who are suffering with the same disease really shouldn't be downplayed. That's pretty important.
Risks? Well, with any treatment for cancer there are risks, unfortunately. We haven't yet come up with treatments that don't have any side effects, and with the clinical trials sometimes we don't know. We don't know all of the potential side effects of a drug fairly early in development. There is a lot of uncertainty. And we also don't always know that the treatment is going to be better than the standard of care.
Trials are designed very carefully to make sure that people are offered at least the standard, and we try to design them as you are either going to get the standard of care, which you would get if you weren't on the trial, or you are going to get the standard of care plus something else. Now, occasionally if we are in a situation where there is no approved agent, where there is nothing that we know helps, then there are still some placebo-controlled trials, but that's not usually the situation. If you are going into a clinical trial, you will know if you are on a study that involves a placebo or not. That's one of the important things to talk to your doctor about if you are looking at a study.
Lung cancer remains a very challenging disease, but we are definitely making progress. In the last five years, we have seen development of many new targeted agents for advanced-stage disease. We have also seen the onset of a time where we are able to use adjuvant therapy, and we are being able to focus now on treating people more individually. Those are areas of very exciting research. I think that as we continue to move forward, the ongoing clinical trials are really leading the way in helping us know where to go.
More Information About Lung Cancer
If you'd like to know more about treatment advances for early stage lung cancer, listen to the entire webcast of Research Advances: Changing Treatment for Early Stage Lung Cancer.
For more information about lung cancer and how to live well with the condition, check out these related HealthTalk features:


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Additional Photos
With over 115,000 people Arvada is the 7th largest city in Colorado and a suburb of Denver. Named by some locals "West Denver", and a first-ring suburb, Arvada is close enough to Denver proper to conveniently take advantage of all of the entertainment and amenities that Denver has to offer, but just far enough to retain its small town charm. Residents have a variety of neighborhood options, including charming downtown historic bungalows and cottages, golf and country club areas, suburban neighborhoods with new construction, farm and equestrian estates and plenty of apartment, condo and townhome areas.
Arvada has grown not only in population but in prosperity and is one of the top wealthiest zip codes in Colorado. It is considered part of the Denver MSA (Metropolitan Statistical Area) and largely in Jefferson County, with a small portion of it extending into Adams County.
In 2016 the real estate website Trulia named part of Arvada as the best neighborhood in Denver. The ranking was based on ease of living a healthy lifestyle, including quiet streets, access to parks and playgrounds and number and proximity of hospitals and care facilities in the area.
Olde Town Arvada is quickly becoming a destination for residents and non-residents alike. A very pedestrian-friendly design and the Olde Town commuter rail line station at Grandview Avenue consistently bring crowds to this little borough marked by historic buildings and an authenticity that can't be faked or developed. Olde Town Arvada is on the National Register of Historic Places, and savvy entrepreneurs have scooped up spaces that now have some of the best eateries and bars in the west Denver Metro.


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When it comes to finding new work, attitude and skill are important, but character is what really counts.
"Every employer wants a positive attitude, but as we understand, attitude and skills will take you to the top, but character is what keeps you up there," said Cesar Valladares of the Department of Public Social Services.
In addition to reeducation for job seekers, the DPSS helps people change their perspective about the job market, Valladares said.
U.S. & World
"What's increasing, what's decreasing, and just change their attitude as to what their looking for work nowadays," Valladares said.
The DPSS serves low-income residents of Los Angeles County through temporary financial assistance, health insurance and other benefits.


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Our automated, data-driven drilling approach was developed by NOV experts from downhole technologies, instrumentation, wired pipe, and rig systems. The system combines industry-leading products and systems with proprietary software and specialists in drilling dynamics throughout each phase to enhance drilling operations. This innovative approach challenges the traditional services model, and it will change the way wells are drilled.
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The success of our automation projects is dependent on the continuous drilling-program process optimization. The iterative process consists of four phases: analysis, planning, execution, and evaluation.
Our eVolve service helped a client improve drilling performance in the Eagle Ford Shale. After an initial benchmarking, six wells were drilled with wired drillpipe feeding the automated control system at surface. The process significantly enhanced performance, with the client achieving an impressive 43% reduction in spud-to-TD time, while maintaining an incident-free rigsite.
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We're the only company in the world that can automate the entire drilling system in house, and we're aligning our automation services with the desired value for all customer segments.
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Tech Update
Upgraded Cradle-Straightener-Feeder
Where traditional units unwind the coil from the bottom, Coe's design unwinds from the top, producing a small slack loop for improved performance. The unit's hydraulic pilot release effectively releases the feeding and straightening rolls, compared to traditional models that do not effectively raise the straightening rolls. Models are available for processing coils to 60 in. wide, 63-in. OD, and weighing as much as 20,000 lb.
Standard features include two driven coil-support rollers, two exit pinch rolls (3.93-in. dia.) and seven straightening rolls (3.93-in. dia.), all synchronously driven. Also standard is hydraulic opening/closing of the alligator-style straightening head for material threading and roll cleaning, a holddown arm with a motorized end wheel, and a snubber/peeler for hands-free material threading.
Coe Press Equipment: 586/979-4400; www.cpec.com
See also: Coe Press Equipment Corporation
Related Enterprise Zones: Coil Handling


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Third-Seeded Tigers Snap FAU's 11-Game Winning Streak
CHAPEL HILL, N.C. – Senior righthander Mike Volpe earned his tenth victory of the season and senior catcher Andrew Parker blasted a monstrous three-run homer as Towson University (30-28) continued its magical post-season with a 7-2 victory over No. 23 Florida Atlantic (39-21) in the first round of the NCAA Regional Tournament at Boshamer Stadium on Friday afternoon.
Volpe, who pitched the Tigers into the NCAA Tournament last Saturday with a 5-2 win over William & Mary in the Colonial Athletic Association championship game, pitched seven very strong innings as the Tigers ended Florida Atlantic's 11-game winning streak.
Volpe, who has a 3-0 record in the post-season, scattered four hits and allowed one unearned run with two walks and four strikeouts as he improved his record to 10-3 on the season. After issuing a leadoff walk to senior centerfielder Nathan Pittman in the eighth inning, he turned the game over to the bullpen. Junior righthander Nik Nowottnick finished the game with a flourish, striking out the side in the bottom of the ninth inning.
Parker, who went one-for-four in the game, helped the Tigers offensively and defensively. He highlighted the Tigers' five-run sixth inning with a three-run homer to left. He also threw out a runner trying to steal and ended a Florida Atlantic rally by picking off Mark Nelson with the bases loaded in the eighth inning.
"It is so great to be back in this environment," said Towson Coach Mike Gottlieb, who guided the Tigers to their first regional appearance since 1991. "It is quite rewarding and I am so thrilled that these guys have the opportunity to experience this."
The win over Florida Atlantic marked the first time in three NCAA regional tournaments that the Tigers won their opening game. Towson will play their second NCAA regional contest on Saturday evening at 6:00 p.m. against the winner of the first round game between host North Carolina and fourth-seeded Canisius.
"When you can get a pitching performance like we received from Mike (Volpe), you have a great chance to win," added Gottlieb. "Obviously, the sixth inning was the turning point in the game. Up until that point, we had been struggling with the bats. But, we turned it around in the sixth inning and gave ourselves a nice lead."
The Tigers' first NCAA regional game in 22 years started off as a pitcher's duel between Volpe and righthander Jeremy Strawn. Strawn shut out the Tigers on two hits through the first three innings before the Owls threatened in the bottom of the third inning. With one out, Pittman drew a walk on a 3-2 pitch to start the rally. Junior leftfielderGeoff Jiminez reached base on an infield single to shortstop to give the Owls two runners on base with one out. After a prolonged at-bat, Nelson was retired on a fly ball to right as Pittman advanced to third base. With Jiminez on first base and Pittman on third, the Owls tried a trick play by having Jiminez break for second base. However, Volpe wasn't fooled and allowed Jiminez to steal second base while Pittman remained on third. Then, Volpe won a six-pitch battle with junior designated hitter Tyler Rocklein by getting him to fly out to rightfield where junior Dominic Fratantuono made the catch.
In the top of the fourth inning, the Tigers scored the first run of the game, thanks to junior designated hitter Kurt Wertz. Wertz led off the inning with a single to centerfield on a 3-2 pitch. Wertz stole second base while Strawn was striking out sophomore leftfielder Peter Bowles. With a runner on second base and one out, Fratantuono reached base when he was hit by a pitch. Wertz advanced to third base when sophomore first baseman Brendan Butler flew out to centerfield. With Wertz on third and Fratantuono on first base, the Tigers tried a delayed double steal. Junior catcher Levi Meyer threw down to second base but sophomore shortstop Mitch Morales cut off the throw and was ready to throw the ball home. But, Wertz had already scored to give Towson a 1-0 lead. Strawn pitched out of the jam by striking out Parker.
Once the Tigers gave Volpe a lead, he got tougher. He retired the Owls in order in the fourth and fifth innings as the Tigers took their 1-0 lead into the top of the sixth inning.
Junior second baseman Pat Fitzgerald led off the sixth inning with a single to centerfield, extending his on-base streak to 28 games in a row. When Wertz lined a double to right centerfield, Fitzgerald reached third base to give the Tigers runners on second and third with no outs. Bowles followed with a single to right centerfield, Fitzgerald scored while Wertz held up at third base.
Fratantuono upped the Tigers' lead to 3-0 when he doubled to left centerfield as Wertz scored his second run of the game. After the double by Fratantuono, Strawn was relieved by junior righthander Kevin Alexander.
Alexander got Butler to hit a weak ground ball to first base where Nelson threw home to retire Bowles, trying to score from third base.
On a 2-2 pitch, Parker launched a long home run well over the left field fence, his 11th homer of the season and the 23rd of his college career. His three-run homer broke the game open and gave Towson a 6-0 lead.
Staked to a 6-0 lead, Volpe retired the Owls in the sixth inning without incident. In the seventh inning, he allowed a one-out single to Meyer, Florida Atlantic's first hit since the third inning. But Volpe retired the next two hitters to preserve the shutout.
With one out in the eighth inning, Butler gave the Tigers a 7-0 advantage with a solo home run to left centerfield. It was his fifth homer of the season,
In the bottom of the eighth, the Owls came to life. After Volpe walked Pittman to lead off the inning, he was relieved by junior lefthander Kyle Paul. Paul got Jiminez to hit a ground ball to shortstop. In his haste to turn a double play, junior shortstop Hunter Bennett committed a rare error as Florida Atlantic had two runners on base with no outs. When Nelson was hit by a pitch, Florida Atlantic had the bases loaded with no outs.
While Paul was pitching to Rocklein, Parker made one of the biggest plays of the game. With Butler playing behind Nelson, the runner at first base, Parker threw down to first base when Butler snuck in behind the runner and he picked him off for the first out of the inning.
The pickoff play proved to be even more important when Rocklein singled to left field, scoring Pittman with the Owls' first run of the game. Freshman second baseman Brendon Sanger followed by hitting a ground ball between first and second base. Fitzgerald ranged to his right and threw to Bennett at second base for the force play while Jiminez scored an unearned run. Senior rightfielder Corey Keller came through with a double down the left field line as Sanger reached third base.
After the double by Keller, Nowottnick came out of the bullpen to relieve Paul. He pitched out of the jam by getting Meyer to ground out to shortstop.
In the bottom of the ninth, Nowottnick nailed down the 7-2 win by striking out the side.
"Getting the big lead in the sixth inning helped me a lot," said Volpe. "I concentrated on keeping the ball down and I was able to throw my curve ball for strikes. I knew it was a big game but I just tried to treat it like any other game and not get too excited. When we got the lead, I just tried to pitch to contact and get through the innings."
Volpe, who became only the third pitcher in Towson baseball history, to win at least 10 games in a season, pitched seven innings and allowed one unearned run on four hits. He walked two batters and had four strikeouts. Volpe allowed only one hit after the third inning and retired 14 of the last 17 batters he faced.
The CAA champion Tigers outhit the Sun Belt Conference champion Owls by an 11-6 margin as all nine Tigers in the starting lineup had at least one base hit. Sophomore centerfielder Richie Blosser and Wertz each had two hits. Wertz was two-for-five with two runs scored while Parker had three RBI's.
With the win, the Tigers reached the 30-win level for the seventh time in school history. The Tigers have now won five games in a row and seven of their last eight games.
TIGER TALES: The Tigers faced Florida Atlantic with regular centerfielder Brandon Gonnella … Gonnella was sidelined with an injury but Coach Gottlieb hopes he will be available for the Tigers' game against either North Carolina or Canisius … When Volpe was charged with an unearned run in the eighth inning against Florida Atlantic, it was the first run he allowed in 11 innings … While improving his record to 10-3, Volpe became the first Tiger pitcher to throw more than 100 innings in a season … He has started a school record 16 games and has thrown a school record 102.2 innings this season.
With the victory, the Tigers improved to 3-4 all-time in NCAA Tournament games … By beating 23rd-ranked Owls, Towson is now 3-5 against nationally-ranked teams this season … Towson went 0-3 against No. 30 Pittsburgh before dropping a 7-1 decision to No. 5 Virginia … The Tigers won two of three games against No. 21 North Carolina Wilmington before beating the No. 23 Owls.


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If you just listened to Republican politicians, you'd have almost no sense that conservative thinking has changed much since Barack Obama beat Mitt Romney over a year ago. But if you hang around the conservative policy wonks, and read certain conservative magazines, the picture is quite different.
I'd invite you, for example, to cast your eye over the new issue of National Affairs, the right-leaning policy journal edited by Yuval Levin. You'll find nine different articles that hang together coherently around what could well be the dominant style of conservatism of the coming years. This is the conservatism of skeptical reform.
This conservatism is oriented, first, around social problems, not government. For many years, conservatives spoke as if runaway government was the only major threat facing the country. Defining themselves against government, Republican politicians had no governing agenda for people facing concrete needs.
But the emerging conservatives begin their analysis by looking at concrete problems: how to help the unemployed move to where they can find jobs; how to help gifted students from poor families reach their potential. If you start by looking at these specific matters, then even conservatives conclude that, in properly limited ways, government can be a useful tool. Government is not the only solution, but it is also not the only problem.
In the lead essay of the issue, Michael R. Strain looks at broken labor markets. Strain embraces some traditional conservative ideas, like streamlining regulations, but also some ideas that use government power: public investments in infrastructure, more aggressive monetary policy, wage subsidies, cash bonuses for people who get off unemployment insurance and find jobs, relocation subsidies to help the unemployed move.
Second, this conservatism is populist about ends but not means. Over the past decade, many Republican politicians have spread the message that the country's problems would be easily solved if only the nefarious elites would get out of the way and allow the common people to take over. Members of this conservatism are more likely to conclude that, in fact, problems are complex and there are no easy answers, but there is room for policy expertise, and perhaps philosophical rigor, even if it comes from Washington.
But these experts should focus on specific needs and desires of working-class Americans, not gripes and obsessions of the Republican donor community. "Modern conservatives have tended to discount the moral value of the average person, focusing instead on extolling the moral superiority of the great." Henry Olsen of the Ethics and Public Policy Center writes. "How many times in recent years have conservative leaders told us about the virtuous entrepreneur?"
Third, this conservatism supports effective government, not technocratic government. Like all proper conservatism, it begins with a sense of epistemological modesty, a sense that the world is too complicated to be centrally planned. Therefore, it opposes the style of government embodied in Obamacare, where officials in the center define insurance products and then compel people to buy them.
This conservatism knows that central decision-makers, even conservative ones, are no match for complex reality. Therefore, they favor market mechanisms, which take advantage of dispersed knowledge. They prefer simple programs to complex ones. In National Affairs, Eli Lehrer and Lori Sanders argue that a carefully structured income support grant could replace the morass of existing welfare programs for the poor.
Fourth, this conservatism is skeptical in temper, especially about itself. Recently, conservatives have been filled with fervor and conviction, and regarded compromise as selling out. Some recent conservatives have ideologized the Constitution, turning it into a rigid system that answers every political question for us. But the founders constructed a constitutional order that left room for different policy approaches; that was humble before the evolving needs of the future; and that required compromise and coalition building. The founders did not believe in concentrating power in the hands of any group of highly fallible individuals.
Today's emerging conservatives embrace that constitutional mind-set, embodied both by Madison and Hamilton. Moreover, the National Affairs authors understand that most policy programs, like most businesses, fail. Conservative programs like urban enterprise zones failed to produce measurable results. Liberal programs like Head Start scarcely produce identifiable long-term gains. Therefore, it is best to approach government in a mood of skeptical reformism: Engage in a constant process of gradual concrete reform even as you are aware that most of your efforts will not pan out.
The Republican style of recent years has produced a vacuum where concrete proposals should be. The emerging conservatives won't have to argue with or defeat the more populist factions on the right; they can just fill the vacuum. Republican politicians, when they are asked to come up with specific programs, will find there is no other game in town.


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NEW YORK (Reuters Health) - Most U.S. adults are eating far more sodium than dietary guidelines recommend, despite decades of health advice urging them to cut back, says a new study.
"People are trying to follow the guidelines, but it's difficult because there's so much sodium in the processed and restaurant food we eat," said Dr. Mary Cogswell who led the study at the Centers for Disease Control and Prevention in Atlanta.
The American Heart Association (AHA) and the U.S. Department of Agriculture recommend that most healthy people limit the sodium they eat to 2300 milligrams a day.
Less than 10 percent of people in the study met this recommendation. Cogswell's team found that most U.S. adults are eating far more sodium than recommended - 3371 milligrams per day, on average.
Regardless of education, age, race, and sex, people are consuming too much sodium, said Cogswell, whose team published their findings in the American Journal of Clinical Nutrition.
Research suggests that a high salt diet can raise blood pressure. On the other hand, it's been shown that potassium may reduce that effect by helping the kidneys get rid of sodium the body doesn't need.
So researchers asked more than 12,000 adults what they ate during the previous 24 hours to get an idea of how much sodium and potassium they were eating. They excluded table salt as it's difficult to judge its contribution.
Dietary guidelines recommend people eat 4700 milligrams of potassium a day-that's about the same amount of potassium as you'd get from 10 bananas or eight sweet potatoes, two of the best sources of the mineral.
But according to the new study, less than two percent of people are meeting the guidelines. Those surveyed ate 2632 milligrams of potassium a day, on average.
People can take action to cut down their salt intake and increase how much potassium they're getting. Dr. Kirsten Bibbins-Domingo, a heart disease specialist at the University of California, San Francisco, told Reuters Health.
"Nearly all fruits and vegetables contain potassium so it is possible to achieve these targets with a diet high in fruits and vegetables generally," said Bibbins-Domingo, who studies the effects of salt intake.
Cogswell suggests that people eat more fresh fruits and vegetables or choose frozen options without sauces, ask that salt is not added to food in restaurants, and read nutrition labels.
"There's a wide variation in the amount of salt in processed and restaurant food. You can look at a jar of tomato sauce and see about 400 milligrams difference between brands," explained Cogswell.
Still, it's not always easy for people to make healthy choices.
"People in poorer communities don't always have many alternatives to choose from; it can be harder for them to find fresh fruits and vegetables," said Bibbins-Domingo, who was not involved in the study.
With close to 80 percent of sodium in the average diet coming from processed food, Cogswell suggests that the food manufacturing industry also has a role to play in reducing dietary sodium.
The National Salt Reduction Initiative - a group of local and national health authorities led by New York State - has set voluntary targets for salt in packaged and restaurant foods. To date, 28 food manufacturers, supermarkets and restaurants - including companies like Heinz, Kraft foods and Subway - have signed up to the targets.
About one in three U.S. adults has high blood pressure, putting them at increased for heart disease and stroke.
According to Cogswell, "even small decreases in the amount of sodium we consume each day (400 milligrams on average) could potentially reduce our risk of (high blood pressure) and the amount we spend on health care."
"The main message is that we're all eating too much sodium and…consumers, through their purchasing power, can to do something about it. Choosing products that say low sodium on the label can make a difference," she said.
SOURCE: bit.ly/MEDTvQ American Journal of Clinical Nutrition, online August 1, 2012.


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Do puddings get more comforting than a cheesecake? Crumble perhaps plays a close second to this decadent, comforting dessert that feels like a warm, sweet hug and tastes like a little slice of creamy heaven.
It sits firmly in the camp of luxurious puddings with crème brulee, panna cotta and ice cream – a real treat but also one which works incredibly well with a spot of sharp fruit involved. Think of crème brulee spiked with the aromatic tang of passionfruit, panna cotta served with a spoonful of stewed, tart blackcurrants providing a beautiful, stark colour contrast too – deepest night-purple against purest white, or vanilla ice cream with raspberry sauce.
I love both varieties of cheesecake – a NY one studded with that all-American favourite, the blueberry, cooked to a gentle wobble and then left to set overnight; or a no-cook number, a classic digestive base coupled with mascarpone or some other cream cheese and double cream and plenty of red fruit swirled through it. You'll notice this recipe is low on the sugar front – because it's so rich I find the filling must be relatively unsweetened – with the base providing a sweet, crunchy finish to the dish. Feel free to add ground or smashed nuts to the base – hazelnuts or pistachios would make a delicious addition. You could easily use frozen fruit here too – just defrost before use.


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Maine church looks at ways to muffle loud steeple bell after complaints
BATH, Maine (AP) � A Maine church is looking to mollify neighbors for whom its bell tolls too loudly.
People in Bath say the First Baptist Church bell has tolled more loudly since the church tower's clock was worked on about a year ago.
The innkeeper at the Kismet Inn says the complaints ring true. She says she likes the bell during the day, but it keeps her guests up at night.
The Times Record (http://bit.ly/HJvuVT ) reports the inn's on the market, but the deal's on hold until the bell issue's resolved.
Church and city representatives say tests will be done in the next couple of weeks looking at different materials and how the bell is struck in an attempt to dampen the noise.
Information from: The Times Record, http://www.timesrecord.com


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Sep 04, 2019
The Lakota Family YMCA is looking for 1-2 Assistant Coaches for our year-round YMCA/USA swim team. We are located just north of Cincinnati in Liberty Township, Ohio. We compete as a member of the Southwest Ohio YMCA Swim League as well as being a USA Swimming registered club. Our club has seen tremendous growth, both in participation and ability level, in recent years. This summer our swimmers have been championship finalists at Ohio Swimming Junior Olympics, USA Swimming Central Zones Championships, and YMCA National Championships. We have an immediate need for 1-2 coaches to lead one of our 10 & Under practice groups. The right candidate for these positions will be someone who enjoys working with younger swimmers and can be enthusiastic on the pool deck, both at practices and meets. This candidate should also have a strong knowledge of the technical aspects of all four competitive strokes, as well as starts and turns. Competitive swimming and/or coaching experience is preferred. Time Commitment: A minimum of 5 hours during the week as well as weekend meets 1-2 times per month. Practice times are currently 5:45-7:00pm. Additional hours (up to 15 per week, not counting meets) are available if desired by assisting with other practice groups. Required Certifications (must be able to obtain within 30 days of hire-Lakota YMCA can assist if needed) YMCA Principles of Swimming and Diving USA Swimming Coach Member – Background Check and Athlete Protection Training included Safety Training for Swim Coaches from an approved organization CPR/First Aid certification from an approved organization This is a part-time position with hourly rate commensurate with experience. Opportunities for additional hours exist if desired through teaching group or private swim lessons and/or lifeguarding at the Y. Please email a resume and short letter of interest to Head Coach, Tom Cuticchia, at firstname.lastname@example.com.
Lakota Family YMCA Stingrays Lakota Family YMCA, Liberty Township, OH, USA Part time


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Collection Items
Map[Part of DeKalb and Fulton County, Georgia : compiled for the use of the Topographical Engineers from the original land map and surveys of DeKalb County Shows parts of DeKalb, Fulton, and Cobb counties. Indicates "rebel works" southeast of "Isoms ford and ferry." Relief shown by hachures. Title and date from Stephenson's Civil War maps, 1989. Original version: Marietta, GA : Topographical Engineers Office, Dept. of the Cumberland / compiled and published between July 5th and July 11th, 1864. Originally printed on 2 sheets, 54 x 35 cm. and 54...
- Contributor: United States. Army. Department of the Cumberland. Topographical Engineers
- Date: 1864