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Atlantic City's Gleaming Vision Has Some Tarnish, Warns Mayor [AUDIO]
The hope of a revived, sparkling, safe and competitive Atlantic City embodied in the newly-approved Tourism District Master Plan is baseless if the city around it is neglected, says Mayor Lorenzo Langford.
After months of painstaking planning consuming lengthy days and interminable nights, repeated public comment sessions and hundreds of thousands of dollars in expense, the Casino Reinvestment Development Authority late last week green-lit their plan to resurrect the fortunes of New Jersey's number-one tourism destination. Governor Chris Christie spearheaded it when he delineated his plans for New Jersey's fiscal future, placing the resort city ahead of New Jersey's race tracks and a failed entertainment venture in East Rutherford.
The CRDA vision is for a vibrant, family-friendly zone centered in the waterfront hotel-casinos, fueled by public-private partnerships and restoring the kinds of revenues that embellish not only the Boardwalk, but programs and services statewide, including those that cater to the elderly and those with physical and emotional challenges.
Langford says he isn't ungrateful for the attention. He just wishes he'd been a guest at the party, not a gate-crasher.
The Governor indicated that the Mayor would be a welcome addition to the team he was gathering to map out a tourism zone that would reverse the fortunes of the Boardwalk casinos that have been decimated by defections to Pennsylvania, New York and Connecticut. But Langford contends that the call never came – and that the Governor needn't bother waiting for his phone to ring, either.
"There's no point in placing itl," Langford bristles. "That horse has been let out of the barn, and the door's been closed. I'm not gonna kiss his ring, and I sure as hell ain't gonna kiss his ass."
Langford supports the CRDA's short-term and mid-range goals. He says they're "in keeping with the Mayor's Strategic Planning Committee." However, he sees some glaring gaps.
"There was no attention given to the Route 30 corridor," says Langford of the highway that offers entrance to the city's north end – an amalgam of casino billboards interspersed with motels, restaurants, small businesses and vacant space fronting marshland. "Certainly if you want to give the impression of being clean and safe and lively, then given the fact that the city has only three ways in and three ways out, and one of those corridors does not present a welcoming feeling…I think that was missed."
Langford says that the plan lacks provisions for turning certain vacant acreage, particularly in the center of town. But overall, he says, he agrees with the CRDA's objectives.
His overriding concern is the concentration of attention on a small part of Atlantic City at the expense of its struggling outskirts. "By erecting real boundaries in the place of what used to be artificial boundaries, plays on the psyche of local residents who have always felt that it was always an 'us-against-them' kind of dynamic," he says. Langford raises the spectre of more than a half-century ago, when racial undertones informed the habit of police asking people what business they had venturing into the two-block stretch from Pacific Avenue to the oceanfront.
The healthier choice, says Langford, is for state elected and appointed officials to consider the city as a complete entity. "I wouldn't have a line at all. It's one city," he says. "You can lend assistance, you can create programs that bring investment from the state to the whole city without the state creating an agency to oversee that."
Listen to a conversation with Mayor Langford.
Segment 1
Segment 2


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A recent series of studies concluded that vitamin supplements A through E were virtually impotent in preventing various forms of cancers. What was the recommendation following these studies? The most effective means of preventing cancers involved healthy dietary selections and performing as much daily exercise as possible. Treadmill desks allow workers to walk throughout the day while working, eliminating the number one reason most employees do not exercise consistently: time.
Treadmill desks allow individuals to feel empowered again. There is significant evidence that daily walking increases productivity, brain function, energy levels, mood and wards off major diseases such as cancers "Study after study is showing that our long term health is dependent upon significant amounts of exercise and healthy diets, yet the focus until recently has been on developing a magic pill that replicates what we can do for ourselves with a little determination and common sense," states Steve Bordley founder of TrekDesk, a treadmill desk manufacturer.
The evidence is overwhelming regarding the health enhancing qualities of daily walking. The challenge is trying to fit in enough time into schedules that involve primarily sedentary activities at a desk. "Walking has been shown to prevent colon, prostate and breast cancer along with a multitude of other diseases. Once people make the connection that they are in control of their health we think you will see more people requesting the option of walking while at work," Bordley stated. Major corporations have taken notice and have already signed on including Humana, Best Buy, GlaxoSmithKliine and Mutual of Omaha.
TrekDesk's website at http://www.trekdesk.com contains excerpts of numerous studies outlining the effectiveness of incorporating daily walking and the correlated reduction in cancer rates. "Treadmill desks allow individuals to feel empowered again. There is significant evidence that daily walking increases productivity, brain function, energy levels, mood and wards off major diseases such as cancers," states Bordley.
The supplement studies, which found no positive correlation between cancer reductions with Vitamins A,B, C, D & E were conducted by some of the most prestigious research centers in the nation including the National Cancer Institute, Harvard Medical School and the National Institutes of Health.
Many of these same institutions have published previous studies showing a direct reduction in cancer risks and other major diseases by individuals engaging in as little as three hours of walking per week.

subset: commoncrawl


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The LEWIS surname appears in Eileen's maternal line. The line stretches back into Canada just after the time of the American Revolution, but it's ultimate origins have not been discovered. Quite possible that the family was American with Loyalist ties.
Stories and History:
Ahnentafel # 48: Nathaniel LEWIS (1791-1830). Nathaniel was born July 13, 1791 in Canada. He married Nancy Ann SNYDER. Nancy was born August 31, 1794 in Colchester Township, Essex County, Ontario. They moved to Montgomery County, Ohio before 1820 and Wayne County, Indiana before 1830. Nathaniel died October 20, 1830 in Hagerstown, Wayne County, Indiana and Nancy died October 17, 1830 in Hagerstown, Wayne County, Indiana. Both are buried in Ulrich Baptist Cemetery, Hagerstown, Indiana.
Ahnentafel # 24: Solomon LEWIS (1820-1895). Solomon was born January 9, 1820 in Montgomery County, Ohio. Solomon married Margaret RINEHART on January 31, 1841 in Henry County, Indiana. Margaret was born July 6, 1822 in Henry County, Indiana. Solomon was a farmer and they raised their family in Huntington County, Indiana. Solomon died December 18, 1895 in Lancaster, Huntington County, Indiana.
Ahnentafel # 12: Jacob LEWIS (1847-1898). Jacob was born January 17, 1847 in Huntington County, Indiana. Jacob married first to Laura GROFF on March 30, 1871 in Huntington County, Indiana. After her death, Jacob married Marietta COOK on November 28, 1878 in Wabash County, Indiana. Marietta was born April 6, 1855 in Grant County, Indiana. Jacob died April 22, 1898 in Lancaster, Huntington County, Indiana.
Ahnentafel # 6: Lawrence Solomon LEWIS (1885-1947). Lawrence was born March 30, 1885 in Lancaster, Huntington County, Indiana. Lawrence married Ruth Alice SILLS on February 24, 1906 in Dora, Wabash County, Indiana. Ruth was born March 29, 1889 in Dora, Wabash County, Indiana. They had 12 children in Wabash County, Indiana. Lawrence died June 26, 1947 in Dora, Wabash County, Indiana.
Related blog posts:


text: The stocks are cheap, and growth prospects for developing nations dwarf those of established countries. By Elizabeth Leary, Contributing Editor November 5, 2012 The emerging-markets "anthem" is as familiar as "We Are the Champions" at sports events: Developing nations, such as China, India and Brazil, are growing faster than the rest of the world, and they stand to deliver outsize stock gains as they industrialize and their middle classes grow. But in recent years, the song has been off-key. Over the past five years, the MSCI Emerging Markets index was essentially flat, compared with a 1.1% annualized gain for Standard & Poor's 500-stock index. In the past year, emerging-markets stocks earned 24.6% and the S&P 500 returned 33.0% (all returns are through October 4). SEE ALSO: Our Special Report on Emerging Markets In part, the bum performance is collateral damage from economic woes elsewhere. Over the past couple of years, many asset classes around the globe have been whipsawed by a phenomenon known as risk-on, risk-off trading. When investors learn of positive developments about, say, the European debt crisis, they scoop up risky investments, such as emerging-markets stocks, in a fit of optimism. When headlines bear bad news, investors sell their risky holdings. "The recent precipitous declines have been driven predominantly by European and other worldwide economic fears," says Howard Schwab, co-manager of Driehaus Emerging Markets Growth Fund. That's understandable, given that Europe accounts for almost 20% of Chinese and Indian exports. But it's also partly because of a self-fulfilling prophecy: Even though many emerging nations have stronger balance sheets and better growth prospects than the developed world, investors think of the stocks as riskier than developed-market stocks, so they treat them as riskier. So the stocks fall disproportionately on bad news and rise disproportionately on good news. Advertisement But many emerging nations also face serious problems. China's economy, which grew at a double-digit percentage pace as recently as last year, is slowing and may expand only 7% to 8% in 2012 and 2013. Any attempt to stimulate the country's economy needs to avoid adding air to China's precarious real estate bubble. And it's possible that less-heady growth will be the new normal for China as it refocuses its economy away from a dependence on exports and government investments and toward greater domestic consumption. All of this is happening as the country goes through a once-per-decade change in its political leadership. The Shanghai Composite index of Chinese stocks dropped 11.6% over the past year. Meanwhile, the economies of big commodity exporters, such as Russia and Brazil, are bound up in China's fate because Chinese demand has been the key driver of commodity prices over the past decade. Although India is less dependent on China, its economy is also slowing. And India is plagued by persistent inflation, trade and budget deficits, and a business environment riddled with corruption and burdened by government red tape. The Wealth Effect Still, in the long run the core reasons for owning a stake in these markets remain unchanged. Emerging markets have huge populations—China and India together account for half of the world's population. And as their economies industrialize, large numbers of people are moving from rural areas to cities—opening up opportunities for them to get a better education and higher-paying jobs. That leads to increased consumption. "Despite the fact that emerging-markets stocks have done relatively poorly, the fundamental picture continues to be strong," says James Donald, co-manager of Lazard Developing Markets Equity Fund. Advertisement Emerging-markets stocks appear to be cheap. The MSCI Emerging Markets index trades at less than 10 times estimated earnings for the coming 12 months, compared with 13 for the S&P 500. Furthermore, many developed nations and their citizens are still at the beginning of a long process of belt-tightening and debt-reduction, and that makes emerging-markets shares look all the more appealing. "The contrast between the long-term-growth outlook for developed and emerging markets couldn't be starker," says Lewis Kaufman, manager of Thornburg Developing World Fund. Some emerging-markets stocks have continued to thrive. Shares of companies that sell goods and services around the world, and those that primarily serve domestic demand, have diverged. Exporters, such as China Shipping Container Lines and state-owned Russian oil producer Gazprom, which depend on a strong global economy, have suffered. But firms that largely serve demand within their own borders—such as Philippine grocer Puregold Price Club and Turkish supermarket discounter Bim Birlesik Magazalar—have performed well and are poised to deliver further growth. If you don't already have a stake in developing markets, start by putting 25% of the money you have dedicated to foreign stocks into an emerging-markets fund. (Before doing so, check to see how much your diversified foreign stock funds have in these markets and adjust accordingly.) Our top pick among broadly diversified funds is T. Rowe Price Emerging Markets Stock (symbol PRMSX), a member of the Kiplinger 25. Manager Gonzalo Pangaro looks for growing companies selling at reasonable prices. He believes that earnings of economically sensitive industries, such as commodity and materials producers, will disappoint for several years as profit margins retreat from recent highs. Advertisement Shares of companies that serve domestic consumption are in some cases much more expensive than those of firms that rely on exports, Pangaro says. But he doesn't mind paying a higher price for a firm with strong growth prospects, such as Turkey's Bim Birlesik or Brazilian department store Lojas Renner. "Companies that are generating earnings growth of 20% per year can quickly grow into their valuations," says Pangaro. Over the past three years, Price Emerging Markets returned 6.6% annualized, matching the MSCI Emerging Markets index's annualized gain. Managers at Driehaus Emerging Markets Growth (DREGX) also prefer to focus on consumer-driven businesses. Schwab and co-manager Chad Cleaver seek companies of any size with above-average earnings growth and a catalyst that is likely to drive stock-price gains. One of their themes has been to shun businesses that are subject to government meddling. For example, Cleaver says, the case for Brazilian mining giant Vale has been hampered by government-levied royalties. And state-owned energy companies in Brazil, China and India have at times found themselves unable to pass higher costs on to consumers because their governments want to keep a lid on prices. Recently, the fund also had 14% of its assets stashed in so-called frontier markets—nations such as Cambodia and Nigeria that don't yet qualify for emerging status. For example, Nigeria's Zenith Bank, a Driehaus holding, has a strong balance sheet and highly profitable lending operations, says Cleaver. The fund returned 9.2% annualized over the past three years, beating the MSCI Emerging Markets index by an average of 2.7 percentage points per year. For a steadier, income-centric approach, consider Matthews Asia Dividend (MAPIX). The fund, also a member of the Kiplinger 25, seeks growing companies that also pay handsome dividends. The fund invests all over Asia, including in developed markets; Japan recently accounted for 24% of its assets. But many of its Japanese holdings, such as Pigeon Corp., which makes maternity, baby- and child-care products, earn a big portion of profits from emerging Asia. "With all of the food-safety scares in China, being a Japanese company has sway," says Jesper Madsen, lead manager of the fund. Advertisement Madsen says he and colleague Yu Zhang have anchored the portfolio with relatively steady stocks. Consumer staples companies account for the largest portion of the portfolio, at 21%. (For comparison, the fund's benchmark, the MSCI All Country Asia Pacific index, allocates 7% to consumer staples.) But Madsen and Zhang are also taking small positions in stocks of economically sensitive businesses that they believe have been overly punished. The fund returned 11.7% annualized over the past three years, with slightly less volatility than the S&P 500. It recently yielded 3.1%. For a zippier approach, consider Lazard Developing Markets Equity (LDMOX), an aggressive fund that seeks companies that are cheap relative to their projected earnings growth. Its managers have loaded up on economically sensitive firms in the industrial, energy and financial-services sectors. Co-manager James Donald says the fund typically races ahead when markets are on a tear. That was the case in 2009, when it gained a stunning 108.2%, compared with 73.8% for the average emerging-markets fund. But the fund will often fall farther than its peers when markets take a dive—witness its 26.3% decline in 2011, compared with the average emerging-markets fund's 19.9% drop. Because of that, Donald says, the fund isn't suitable as a core emerging-markets holding. But it can be a nice complement to one of the more conservative funds. If keeping costs down is a priority, consider Vanguard Emerging Markets (VWO), an exchange-traded fund that tracks the MSCI index and charges just 0.20% in annual expenses. You'll have a larger position in some of the big natural-resources firms and other economically sensitive industries than you would with some other options, and that could make for a bumpier ride. But if your aim is to hold on for the long haul, the fund is a fine choice. Kiplinger's Investing for Income will help you maximize your cash yield under any economic conditions. Subscribe now!


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Reel World
Why We Discuss—Why We Fight, the Grand Jury Prize winner at the 2005 Sundance Film Festival, will begin screening this weekend at the CCA Cinematheque in Santa Fe. The documentary explores the economic underpinnings of the American military and the economic necessity of war. This Saturday, March 11, directly following the 7 p.m. screening, there will be a panel discussion featuring Col. Richard Rael (commander of the 515th Corps Support Battalion in Operation Iraqi Freedom II), William Morgan Stewart (Time magazine bureau chief in the Middle East), Zelie Pollon (cofounder of the Independent Press Association), David Bacon (Green Party 2002 gubernatorial candidate) and Alex Rubin (UNM assistant professor). Tickets for the screening, panel discussion and reception are $10. Donations will be accepted at the reception to benefit Veterans For Peace. The CCA Cinematheque is located at 1050 Old Pecos Trail. Tickets can be reserved by calling the CCA box office at (505) 982-1338.
Film Review
Failure to Launch
Abort! Abort!
Occasionally, moviegoers like to play a game called "What the hell is wrong with film critics?" In this game, they attempt to figure out what it is that makes film critics so different from ordinary folks. Clearly, people who review movies for a living are a pack of crusty old player-haters. How else to explain the fact that, say, that jerk from the Alibi hated Big Momma's House 2? Big Momma's House 2 was hilarious! It was the No. 1 movie in America! Obviously, the guy hates film and knows nothing about the tastes of the average American.
Film Review
The Libertine
Depp's historical drama explores all the uses of the word "dirty"
The controversial new Johnny Depp-led historical drama The Libertine hews closely to England's long and proud tradition of Mud, Blood and Horse Crap-style realism. This school of thought believes that the more mud, blood and horse crap you show on the screen, the more historically accurate the film will seem. While The Libertine does look as dimly lit and disease-ridden as possible, it doesn't necessarily translate into a particularly pleasant moviegoing experience.
Idiot Box
Host-Traumatic Stress
An Oscar night wrap-up
Now that it's all said and done, let's put aside the minuscule controversies (Crash won! Rap songs are now guaranteed Oscar material!) and look at the actual show. How was the "78th Annual Academy Awards" telecast? In a word (OK, two): rather dull.
Week in Sloth
The Week in Sloth
"Build a Better Burger" (Food Network 7 p.m.) You ask, Food Network, for the nigh impossible! What innovations are left for that humble hallmark of our fast food nation, the hamburger? Tonight, a group of cook-off contestants will answer that question as they vie for a $50,000 prize.
"Battlestar Galactica" (Sci-Fi 8 p.m.) Who would have guessed that this season would end on a "West Wing"-inspired cliffhanger? Will President Roslin fix the vote or will she allow crazy Cylon puppet-boy Balthar to take over the space fleet's highest office? At least Sci-Fi is giving us a 90-minute finale in which to wrestle with such thorny political issues.


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UEFA Europa League: Real Betis 0 Sevilla 2
Nono's penalty miss for Real Betis gifted Sevilla a place in the UEFA Europa League last eight after a stunning second-leg comeback.
The visitors won 2-0 on the night to overturn Betis' first-leg lead and then held their nerve in the penalty shoot-out, despite Vitolo missing their first kick.
Goals from Jose Antonio Reyes and Carlos Bacca either side of the break on Thursday inflicted Betis' first home defeat of the season in Europe and it was Sevilla who prevailed from 12 yards, as Alfred N'Diaye and Nono let Vitolo off the hook.
The result marked the first time Sevilla have overturned a first-leg home defeat in UEFA competition, leaving the hosts to focus on their battle for La Liga survival.
Having lost the first leg to goals from Leo Baptistao and Salva Sevilla, Unai Emery named a bold starting XI at Benito Villamarin, with Bacca and Kevin Gameiro starting together in attack.
With Betis sitting on the first-leg lead, the visitors were invited forward right from the start and they went close to finding the net in the 11th minute, but Gameiro narrowly failed to reach Bacca's low cross.
Sevilla attacked relentlessly in the opening stages and took a deserved lead 20 minutes in as Reyes slotted Alberto Moreno's left-wing delivery into the bottom-left corner.
Gabriel Calderon's Betis struggled to create any kind of momentum but will count themselves unfortunate not to have been awarded a penalty just after the half-hour mark, with the ball appearing to strike Diogo Figueiras on the arm.
Betis' aggregate lead was almost wiped out three minutes into the second period as Stephane M'Bia played a one-two with Gameiro before shooting straight at Adan from point-blank range.
After a nervous start to the second half, Betis started to show more attacking intent as Ruben Castro headed wide 55 minutes in, before Baptistao struck just wide from 25 yards less than a minute later.
Sevilla goalkeeper Beto kept his side in with a shout thanks to a crucial stop in the 64th minute, parrying Baptistao's half-volley after a clever chipped pass by Nono.
And the away side drew level on aggregate 15 minutes from time as Moreno exploited space down the left before drilling a low cross into the danger area for Bacca to knock past Adan unchallenged.
With the score level after 90 minutes, the match entered extra-time and Sevilla should have clinched the tie.
Adan pulled off an excellent stop when one-on-one with Gameiro, before palming away Bacca's headed effort on the rebound.
The Betis keeper saved from Vitolo to give the hosts the early edge in the shoot-out, but N'Diaye struck the post and Nono dragged wide to give Sevilla a place in the quarter-finals.


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Vitamin D is a hormone produced by human skin in response to the Sun and to other sources of ultraviolet-B (UVB) light. Our vitamin D blood levels are lower in the winter due to the lower angle of the sun and the resulting reduced amount of natural UVB light. Blood levels are "highest in late […]View Post
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|Oracle® Fusion Middleware Developer's Guide for Oracle IRM Server
11g Release 1 (11.1.1)
Part Number E12326-03
|PDF · Mobi · ePub
This section contains the following topics:
Resealing is the process of altering the custom metadata or editing the encrypted content. Oracle IRM Desktop allows certain formats, such as Microsoft Office, to be edited in sealed form. The process of saving edits is called resealing.
The sealing server supports resealing to update the custom metadata but does not support updating the encrypted content of the sealed file. Content is uploaded to the sealing server, the custom metadata is updated, and the sealed content is returned to the caller.
For JAX-WS generated web service proxies, the content is provided as a
DataHandler parameter. Using a data handler allows the web service stack to stream the binary content to the server without having to load the complete file into memory.
javax.activation.DataHandler input = new javax.activation.DataHandler(new FileDataSource("example.stml"));
The data source does not have to be a file.
A call to reseal requires the sealed data (in the form of a
DataHandler) and the custom data for the update. The following demonstrates how to reseal a sealed file using the
reseal method adding XML-based custom data to the sealed file.
The XML based custom data is provided as an XML element.
Element element = document.createElement("SampleCustomData"); element.setTextContent("Some example custom data provided as an XML element containing this text"); CustomData data = new CustomData(); // UUID identifies the custom data, this example uses a fixed example UUID value data.setUuid("7f79d1e8-fc07-464c-8477-834951e07060"); // Custom data is XML document data.setData(element);
Then the
reseal operation is called to reseal the content and re-sign the metadata.
SealingServices sealingServices = new SealingServicesService().getSealingServices(new javax.xml.ws.soap.MTOMFeature()); DataHandler results = sealingServices.reseal(input, new CustomData[] {data});
To call the
reseal operation, the authenticated user needs rights that allow the reseal feature to be performed for the classification of the sealed content.
DataHandler class can be used to write out the resealed content to an output stream of the programmer's choice. This example shows the resealed content being written out to a file.
java.io.FileOutputStream outputStream = new java.io.FileOutputStream("example.stml"); results.writeTo(outputStream); outputStream.close();
Resealing is the process of altering the custom metadata or editing the encrypted content. Oracle IRM Desktop allows certain formats, such as Microsoft Office, to be edited in sealed form. The IRM Java API allows the custom metadata to be altered. Custom data is provided as an XML element, this code does not show how the XML element is created, just how to use a XML element with custom data. The Java API for XML Code Samples show how to create and manipulate XML documents.
org.w3c.dom.Element element = ...
Custom data entries are identified with a UUID value.
java.util.UUID uuid = java.util.UUID.fromString("7f79d1e8-fc07-464c-8477-834951e07060");
As sealed content can contain multiple custom data entries, each one must have a unique UUID value. This value can be used when peeking the content to identify the custom data. This example uses just one custom data entry.
import static oracle.irm.engine.content.sealing.CustomDataFactory.createCustomData; import static oracle.irm.engine.content.sealing.CustomDataCollectionFactory.createCustomData; import oracle.irm.engine.content.sealing.CustomData; ... // Create custom data, identified by the UUID value CustomData data = createCustomData(uuid, element); // Resealing allows multiple custom data entries, and expects a collection type java.util.Collection<CustomData> data = createCustomData(data)
Once the custom data has been created, the reseal operation can then be called to reseal the content and re-sign the metadata.
import oracle.irm.engine.content.sealing.CustomData; ... // Sealed file provided as a file java.io.InputStream input = new java.io.FileInputStream("sealed.stml"); // Resealed file written out to a file java.io.OutputStream output = new java.io.FileInputStream("resealed.stml"); // Reseal the sealed content, altering the custom data reseal(input, output, data);
To call the reseal operation, the authenticated user needs rights that allow the reseal feature to be performed for the classification of the sealed content.


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The United States is ankle deep in our quadrennial political ice water swim known as a presidential election campaign. With the Democratic candidate (and current president) running unopposed and the Republican side of the ticket pretty much down to a field of two, we know that multiple sclerosis has been a part of the life of each of these three candidates.
Politics aside (like that's attainable!) I'd say that the discussion of MS and the White House is worth having on this day before the largest primary vote of the season to date. To ensure full disclosure, I have decided for whom I hope to vote in November but will try to keep that out of our conversation. That should, actually, be pretty easy as I'd like this to be a discussion about MS in the national political conversation.
To begin, the relationships:
- President Obama's late father-in-law lived with MS. The First Lady mentioned it prominently in her husband's last run for the office.
- Former Speaker of the House Gingrich's former wife was diagnosed with MS while they were married.
- Former Governor Romney's wife lives with MS and has served on the board of her local chapter of the National MS Society.
In no particular order, I'll start with Mr. Gingrich:
During the recent South Carolina primary campaign, it came to light in an interview with the former Speaker's wife that he asked for a divorce not long after her diagnosis. The accusation sparked an impassioned response and denial from the candidate at a televised debate days prior to the vote. Days after, the campaign changed course and advised that Gingrich did know of his wife's MS when he asked her for a divorce.
Also notable: Gingrich's first wife was asked for a divorce while under treatment for cancer.
Now, Mr. Romney:
Some (even some in the MS community) are surprised to hear that Ann Romney, the former governor's wife, lives with MS. Even though the two have been interviewed on the subject, it doesn't come up much in political conversation.
Mrs. Romney isn't secretive about her disease and the campaign website states that her MS "has been in remission since 2002."
Though one online bio of Mrs Romney's states that she is a board member for the New England chapter of the National MS Society, she left that position when her husband began his run for the 2008 Republican nomination (because, according to the Society, it "is a not-for-profit organization that must maintain a non-partisan stance in the political arena. We have not worked directly with Ann since that time.").
Finally, President Obama:
Mr. Obama brought his connection to MS with him to the Senate, but we haven't heard much of it since his election to the Oval Office in 2008.
While Mrs. Obama's experience growing up with MS in the family is obvious, she has taken on the cause of childhood obesity as her calling as First Lady (though a very worthy calling, many of us were hoping that MS would figure more in her public persona).
While I have an opinion on all of this, I'll wait until the general election before I start spouting off on the topic. For now, I'd like to hear your thoughts on the candidates' connections to MS.
Will this shared connection influence your vote? Do you think any one relationship is good or bad for our cause? Do you think MS will matter once the election is over?
Gearing up for a long nine months until the election and, as always,
Wishing you and your family the best of health.
Don't forget that you can also follow me via my Life With MS Facebook page and on Twitter. Check out our bi-monthly blog I'm doing for the Multiple Sclerosis Society of the United Kingdom, A Yank's Life With MS, as well as our very special new monthly blog for the National MS Society.


text: Ammyy Admin Crack 3.5 Activated Full Version Free DownloadAmmyy Admin Crack Activated Free Download Ammyy Admin Crack is remote desktop software used for sharing and server control. It is very easy to use and requires no installation and works like charm. It is very fast and can be used without problems on the slow networks. It is compatible with the …Read More »


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> PLEASE CHOOSE ONE <Bakery Roll Amoroso Roll
> PLEASE CHOOSE ONE <American Swiss Provolone Mozzarella No Cheese
> PLEASE CHOOSE ONE <Hot Toasted Neither Hot or Toasted
The location and menu you have chosen is currently closed and unavailable for immediate orders.
You may continue to place your order, but the earliest time the order will be ready is:
Delivery : Friday, February 21 @ 4:55PM
Pickup / Dine In : Friday, February 21 @ 4:25PM
I understand. Continue my order...


text: Prelude 1/2 Violin D - nickel/steel: medium Catalog ID: STVNPRE33_1NIB Prelude violin strings are manufactured using a solid steel core. Unaffected by temperature and humidity changes, they have excellent bow response. Prelude strings have a warm sound in a solid steel core string design.Scaled to fit 1/2 size violin with a playing length of 11 1/2 inches (290mm), these medium tension strings are optimized to the needs of a majority of players. Packaged in uniquely-designed sealed pouches providing protection from the elements that cause corrosion. Brand: Prelude String: D String Size: 1/2 Winding Material: Nickel Core Material: Steel Gauge: Medium String End: Ball In Stock List Price: $10.75 $4.84 Buy Continue Shopping


text:
I was playing around with zip and accidentally deleted my /home/ folder (I wanted to delete home/ which got created by unzipping an archive).
I used
rm -r /home/instead of
rm -r home/ as root. Is there anything I can do to restore my /home/ dir?
I am using Debian 6 as a VM on VMware Player. Unfortunately I have no backups.


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Ask the cubicle expat: Help! My star client has begun making unreasonable demands on my time!
January 29th, 2011
L. asks: One of my favorite copywriting clients has me on a retainer, which usually works out very well for us both. However, in the last two months a third project manager has been added. My lovely retainer has gone from well-managed to every reason to say "no" to such work in the first place: non-stop emails, minuscule timelines, and repeated fires. When I talk to the PM and try to correct the behavior, her response is, "Just tell me and I'll get another writer." (A family member of hers is a copywriter.) My three contacts are peers, so I'm not sure how to best broach the issue. I'd hate to lose the client, but things do need to change. Any recommendations? Thanks!
I answer: Ack! I feel your pain! Obviously this is not a sustainable situation or you wouldn't be writing to me. Some suggestions (feel free to mix and match as you see fit):
1. Meet with all three managers (or whomever was your initial contact) and tell them you can better serve the company by having one point of contact, not three. Make it about the benefits to their business (more efficient, more personalized attention, whatever) than the benefits to you. If you only meet with one of your contacts, don't badmouth the others; be diplomatic.
2. Let the client(s) know that the workflow has changed and it's no longer efficient. (Last minute requests mean you're not always available that minute or you have to do a rush – and thus, less than ideal – job.) Suggest that they funnel all requests into one daily or weekly phone meeting or email. Any other requests will have to wait until the next meeting/call.
3. Since I don't know what you're making on this gig, how many hours you've agreed to work, and how many hours you're actually working, it's hard to get super-specific on how much more money or what timeframe limitations to ask for. But clearly you're being subjected to scope creep, which can only mean one thing for a freelancer: you're working more for the same amount of money, which means you have less time for other clients and essentially are losing money. This has to stop!
Tell your client(s) that the parameters have changed and you'd like to renegotiate. You can put a time cap on the hours you devote to them each week, you can ask for more money, or you can ask to reconfigure the pay structure (instead of retainer they pay you per hour or project). If what's happening is that they expect you to be on call 40 hours a week but are only paying you for 10 hours' worth of work, I'd say you're getting the short end of the stick. If they want you on call all week long, they should give you a full-time contract.
4. Speaking of contracts, do you have one? If so, I'm guessing they're violating the terms. Even if you don't, it sounds like it's high time you mentioned – nicely – that they're not sticking to the agreement you made at the start of the project and since the parameters of the job have changed, you'd like to renegotiate. And this time, get all the terms in writing so you can point to them later if things go haywire again.
If the client finds any of these requests so unreasonable that they feel they need to hire a family member they can abuse instead, it sounds like you'll be dodging a bullet by letting them go, regardless of whether they're friends of yours. It's just business; in fact, letting them go might prevent any damage this situation is causing to your friendship. Also think of all the time you're wasting and money you're losing on this gig. Instead you could focus those however many hours a week on replacing that client with a saner one.
Good luck with this!
Folks, if you want to hash out client problems like this with me and a group of your freelance peers, check out my online class on dealing with nightmare clients, which starts Feb. 5 and still has openings. Details here.
Entry Filed under: Ask the Cubicle Expat,Events
2 Comments Add your own
1. GoOctopus Job Search | February 20th, 2011 at 11:49 pm
To be honest, most of problems from workplace are generated from "afraid to talk". If you don't take steps, the problem will become bigger and bigger.
2. Michelle H | February 22nd, 2011 at 12:57 am
Ugh. This is a sticky situation to be in. I feel your pain L. Great advice given once again by Michelle G. I hope everything works out for the absolute best.
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So yeah, adding another co-blogger was theoretically supposed to increase frequency of posting, but then A Sarah and Fillyjonk both had the nerve to go out of town and have lives or something, and Sweet Machine and I have both been dealing with shit that keeps us away from the blog, and I got really caught up in following and writing about Dr. Tiller's murder, and here we are.
So, two things, before I tell you to talk amongst yourselves.
1) Reminder: Marianne and I and Lessons from the Fat-o-Sphere contributor/Fatshionista extraordinaire Lesley Kinzel will be reading, signing books, and hanging out at Re/Dress in Brooklyn this Friday night, June 5, starting at 6 p.m. Deets:
Re/Dress NYC
109 Boerum Place
Brooklyn, NY
between Pacific + Dean
f/g train to Bergen Street stop
Shopping at 6:30, reading begins at 8.
Fillyjonk will be there, too, and there will be a dance party afterwards, and refreshments, and all the fatty vintage shopping you can handle. Come on down!
2) This article pissed me off on so many levels, I don't even want to get started. I'll just quote from a gchat I had with Fillyjonk yesterday.
FJ : was that the article about how there are fewer plus size fashion shops/lines because of lack of demand?
unlike every other segment of the retail economy, which is just zipping along?
life and style reporters are probably going to be sucking that teat for a while
"demand for popsicles is down!"
"demand for furbies is down!"
me: "demand for newspapers is down!" oh, wait.
[There is some discussion of just posting inflammatory quotes from the article and letting Shapelings have at it.]
me: "For one, plus-size collections are expensive to make—as much as 10% more than standard lines, experts estimate—because they require additional fabrics, and special fit models and patterns."
SPECIAL fit models and patterns. The other ones are normal, so they don't count.
Or cost money.
"'They're really bargain shoppers,' says Catherine Schuller, a plus-size expert and former editor at Mode, a magazine for larger women. Many are homemakers who can't spend considerable amounts on clothes and are willing to sacrifice their own spending for their families, especially now, Ms. Schuller says."
Um, with all due respect to the segment that fits that description, if that's your understanding of the entire fatty fashion market, maybe I get why Mode failed.
FJ: maybe i should write something
it would have to be really short and horrible
me: And the one that really got me: "Because these shoppers prefer to buy online, according to industry insiders…"
FJ: aaaaaaaaaaaaa
Me: Which extends to the fact that, if we go to the mall, it's to see if the one fat store has anything that fits us, so there's not so much point in going to the damned mall
Whereas people buying straight sizes can go to the mall to try on things at 20 stores.
FJ: right! but no, it must be because WE PREFER TO SIT IN OUR HOUSES AND WALLOW IN SHAME
Me: Also, once again, a company's marketing fail gets blamed on the market.
How many Shapelings have said, "Wait, Ann Taylor carries up to 18? I had no idea."
And then no one comes in and buys those sizes, so obvs, the market doesn't exist
FJ: it's as though they have to rediscover marketing for the plus-size market
"well, for normal-size people, we make a product and tell them how great it is, and then they buy it"
"for fatties, i think maybe we should try pretending the product doesn't exist and see how that goes"
me: Ha, no kidding! We'll cram a couple of plus sizes in the back, never say anything about it, and just wait for the customers to arrive! It's a plan!
FJ: we'll be rich! rich!!
me: Also, it's important to have a deep understanding of the market…
So here's what you need to know:
They never leave the house. They don't like to spend money. They don't want to look attractive.
FJ: they're unlovable & they eat too much
they probably own one million cats
we did a lot of focus groups
on 4chan
me: HA!
There you go, Shapelings. What else would you add? What else do you want to talk about? Thread is yours.
(Oh, I just realized SM put up a fluff post while I was writing this. Oh well. Now you'll have TWO threads to muck around in!)


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Missouri State Genealogical Association
2010 Conference Schedule
Jefferson City, Missouri
Friday, August 13-Saturday August 14, 2010
9:30-11:30-- Pre-conference Workshops (Additional $20 fee)
Workshop 1: If You Don't Tell the Story, Who Will? With Marilyn Collins. The search for family ancestors is the primary focus of genealogists. This workshop comes into play after the charts are complete. Learn how to write the story of a family, town, church, people, or events.
Workshop 2: When the Records Didn't' Get It Right, with Mary Celeste, MLS. If your family consists of names, dates, and places only, you may have missed out on really getting to know some interesting characters. In this workshop you will be inspired to roll up your sleeves, dust off your resources, call your cousins, and get back into the research mode. This is an interactive program.
9:30-1:00 -- Registration
1:00-2:00-- Conference Begins
Keynote Presentation: Civil Records in Germany, Roger Minert
2:30-3:30-- Breakout sessions
Researching Your Missouri Czech (Bohemian) Immigrant, June Sommer, MLS
Searching High and Low: Using Cartographic Records in Genealogical Research, Patricia M. Luebbert
4:00-5:00-- Breakout sessions
Overcoming Brick Walls When Researching Our Family History, Gene Block
The Rope and the Open Square: Civil War Crime and Punishment, Tom Pearson, MLS
6:00-- Banquet: Self-Defeating Behaviors in German Family History Research, Roger Minert
8:00-9:00-- Registration
8:30-9:30-- Troubleshooting in Germanic Family History Research, Roger Minert
10:00-11:00-- Breakout sessions
History Through Genealogy—Researching "Dred and Harriet Scott: Their Family Story", Ruth Ann (Abels) Hager, CG, CGL [Book signing to follow]
St Louis At War, 1861-1865,Tom Pearson, MLS
11:30-1:00-- Luncheon and Annual Meeting
1:15-2:15-- Surname Changes in Northwestern Germany, Roger Minert
2:45-3:45-- Breakout sessions
Heritage Societies, Certificate Programs, and Lineage Research Projects, Mary Celeste, MLS
Ireland Here and There, Suzanne Vinduska and Maria Forsha
More info / to register: http://www.mosga.org/conference2010.html


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Authentic Chanel handbags outlet
In this review we will tell you about the Authentic Chanel handbags outlet, which are manufactured by CHANEL. Read, see photos of the Authentic Chanel handbags outlet which differ in shape and size, design and color schemes. Share with your friends!
Before you see the photos of Authentic Chanel handbags outlet, we offer insight into the history.
Chanel Company is known to have stated in the beginning of the last century and since then it has developed into a world-famous fashion leader being recognized throughout the world. Gabrielle Bonheur Chanel preferred to be referred to as Coco, revolutionized the fashion world of the 20th century. It all started with selling hats in a small Parisian shop in 1909. 1919 was the year of opening of the Chanel Fashion House, and 1920 was the year when the classical little black dress was introduced to the world. 1921 is one more turning point, but now as far as fragrances are concerned – she makes «Chanel №5»
February, 1955 is the time for bags – the fashion world welcomes the fabulous Chanel 2.55, which has to become the most outstanding and well-known women's bags in history.


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Available Options:
Dr. Wright brought this spiritual cleansing technique back with him from Burma where he was a cultural attache. The principle technique he learned and practiced is a variation on what is called the "breath of fire" in Hatha Yoga. But what Dr. Wright learned is a separate discipline in its own right because it employs a specific combination of breath and focused intentionality to spiritually cleanse the body, section by section. The rhythmic breathing clears the aura almost scientifically. Healing can take place "out of the overflow of spirit," as Dr. Wright says.
Saraswati Publications, LLC | 3300 NW 185th Avenue, #92 | Portland | OR | 97229 | © 2012 | Privacy Notice


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CLR News
Continental Resources Increases Proved Reserves 54 Percent To 785 MMBoe
Company's Bakken Proved Reserves Almost Double, Exceeding a Half-Billion Barrels of Oil Equivalent
58 Percent Estimated Production Growth Achieves 2012 Target
PR Newswire
OKLAHOMA CITY, Jan. 23, 2013 /PRNewswire/ -- Continental Resources, Inc. (NYSE: CLR) increased its year-end 2012 proved reserves to 785 MMBoe (million barrels of oil equivalent), a year-over-year gain of 54 percent. With the 2012 increase, Continental has grown proved reserves at a compound annual growth rate of 45 percent since year-end 2009.
(Logo: http://photos.prnewswire.com/prnh/20120327/DA76602LOGO)
Continental's 2012 proved reserves had a net present value discounted at 10 percent (PV-10) of $13.3 billion, a 45 percent increase over the PV-10 of $9.2 billion for proved reserves at year-end 2011.
Proved reserves growth in 2012 primarily reflected strong production growth in the Bakken play of North Dakota and Montana, which Continental believes is the nation's premier oil play. Continental is the largest producer and leaseholder in the Bakken, with approximately 1.1 million net acres. The Company has also accelerated production growth in its South Central Oklahoma Oil Province (SCOOP), an oil- and liquids-rich play in Oklahoma.
Thirty-nine percent of Continental's total 2012 proved reserves, or 309.0 MMBoe, were proved developed producing (PDP), compared with 40 percent of year-end 2011 proved reserves.
Crude oil reserves represented 72 percent of 2012 total proved reserves, a significant increase over year-end 2011, when crude oil accounted for 64 percent of the Company's 508 MMBoe in proved reserves. The higher percentage of crude oil proved reserves in 2012 was accomplished despite two crude-oil concentrated divestitures.
Continental currently operates 85 percent of its total proved reserves, compared with 86 percent at year-end 2011.
"We continue to increase our concentration in high-value, high-growth, crude oil assets, especially in the Bakken," said Harold Hamm, Chairman and Chief Executive Officer. "We are growing the value of our Bakken assets through strategic acquisitions, exploration, and the expanded use of pad drilling, which should improve efficiencies and translate into even better rates of return."
Through acquisitions and leasing, Continental increased its Bakken leasehold by 24 percent in the past year, from 915,863 net acres at year-end 2011 to 1,139,799 net acres at year-end 2012.
The Company is also leveraging the increased demand for high-quality Bakken crude oil at U.S. refineries. "We have more than adequate pipe and rail capacity out of the basin at this time, so we can move our production to the most advantageous markets," Mr. Hamm said. "Realizing the Bakken's full potential is essential to our five-year plan to triple production and proved reserves by year-end 2017, while increasing operating margins."
Strong Production Growth
Estimated fourth quarter 2012 production was 9.8 MMBoe, or 106,831 Boe per day, a 42 percent increase over fourth quarter production for 2011. The Company deferred some fourth quarter well completions to stay within its capital expenditure budget for 2012. Fourth quarter 2012 was the 19th consecutive quarter in which Continental has increased production compared with the immediately previous quarter.
Based on continued production growth, as well as an acquisition and a divestiture announced December 20, 2012, Continental's current production is approximately 116,000 Boepd.
Increased Proved Reserves
Other significant components of year-end 2012 proved reserves included the SCOOP play in Oklahoma, with proved reserves of 63 MMBoe (PV-10 of $955 million) and the Red River Units, where proved reserves increased in the past year to 78 MMBoe (PV-10 of $2.0 billion).
Exploration and development activity was the primary driver in the Company's 2012 proved reserves growth, adding 234 MMBoe of proved reserves in the year, of which 27 percent were PDP and the remainder PUDs (proved undeveloped reserves). In total, a reconciliation of 2012 proved reserves included:
Also notable was the fact that the Company for the first time booked proved reserves in lower benches of the Bakken Three Forks formation, with the recognition of three PDPs and 11 PUDs in 2012. Continental has completed two wells in the Three Forks second bench and one well in the third bench. Traditionally operators in the play targeted the Middle Bakken zone above the Three Forks and only the first bench of the Three Forks zone.
Ryder Scott Company, L.P. evaluated properties representing 98 percent of the Company's proved reserves and 99 percent of Continental's PV-10 at year-end 2012, with Continental reserve engineers evaluating the remaining properties.
Continental has two major exploration/appraisal programs planned for 2013. The Company is testing productivity of the lower Three Forks benches with a 14-well program at locations across the play. In addition, the Company has initiated the first of four increased density pilot programs that will involve multiple wells in the Middle Bakken and the first three benches of the Three Forks zone, to test the appropriate density for full development. Successful results from these programs would prove commercial productivity and could significantly impact future reserve bookings.
The Company expects to begin reporting results from new lower-bench productivity tests quarterly over the next 12-to-18 months.
"2012 was a good year for Continental. We completed the move of our headquarters to Oklahoma City, and we increased our focus by selling mature properties and redeploying capital to higher growth-rate assets," said Rick Bott, President and Chief Operating Officer. "We have expanded our land position, increased production, increased proved reserves, embarked on an ambitious exploration/appraisal program, retooled our marketing efforts, secured capital to fund our ongoing growth, and continued to build our leadership and technical staff.
"As we begin 2013, we see multiple catalysts and opportunities to enhance the value of our operations, particularly with these lower Three Forks programs and further delineation of our SCOOP acreage. 2013 looks to be as exciting as 2012," Mr. Bott said.
About Continental Resources
Cautionary Statement for the Purpose of the "Safe Harbor" Provisions of the Private Securities Litigation Reform Act of 1995
The Company cautions readers that these forward-looking statements are subject to all of the risks and uncertainties, most of which are difficult to predict and many of which are beyond the Company's control, incident to the exploration for, and development, production, and sale of, crude oil and natural gas. These risks include, but are not limited to, commodity price volatility, inflation, lack of availability of drilling and production equipment and services, environmental risks, drilling and other operating risks, regulatory changes, the uncertainty inherent in estimating crude oil and natural gas reserves and in projecting future rates of production, cash flows and access to capital, the timing of development expenditures, and the other risks described under Part I, Item 1A. Risk Factors in the Company's Annual Report on Form 10-K for the year ended December 31, 2011, registration statements and other reports filed from time to time with the SEC, and other announcements the Company makes from time to time.
Readers are cautioned not to place undue reliance on forward-looking statements, which speak only as of the date hereof. Should one or more of the risks or uncertainties described in this press release occur, or should underlying assumptions prove incorrect, the Company's actual results and plans could differ materially from those expressed in any forward-looking statements. All forward-looking statements are expressly qualified in their entirety by this cautionary statement. This cautionary statement should also be considered in connection with any subsequent written or oral forward-looking statements that the Company, or persons acting on its behalf, may make.
Except as otherwise required by applicable law, the Company disclaims any duty to update any forward-looking statements to reflect events or circumstances after the date of this press release.
SOURCE Continental Resources


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Artist: Andre Williams and The Sadies
Album: Night & Day
A new year is upon us, full of great new music to explore, but before we move on to embrace the new it's always a good idea to look back and see if there was anything we missed. This is especially important now; in the era of disposable information, where we glut and feast on new facts as frequently as possible, fantastic things can get overlooked – buried alive, as it were.
Andre Williams and The Sadies is just one of the blips that you might have missed. Their album Night & Day was released in May of 2012, and is absolutely alive with verve and pockmarked soul. This is rhythm and blues at its grittiest, 70s-style traveling music at its catchiest, and features vocals with so much character that they seem to growl and snap at your elbow with every listen.
The lyrics range from topics of bitter love ("Hey Baby!", "Me And My Dog") to threats of violence ("Your Old Lady", "Bored") and thwarted jail time ("I Gotta Get Shorty Out of Jail"). The world of Night & Day is indeed often more night than day, with a kind of casual callousness broadcast in every song. In "America (You Say "A Change Is Gonna Come")" Andre Williams spits out his philosophy against a background of organs and supporting vocals that evoke a blend of both haunted house and gospel house, spirits and the spiritual: "cuz without cash you're trash, you gotta be blessed to live in America." The result is an intoxicating moodiness as rich as any top shelf cocktail.
The following song may contain lyrics that are offensive to listeners.
Andre Williams has the deep, purring bass of a jungle cat, his voice percolating through his saliva to rattle out his threats and observations. If Andre is the night of Night & Day, then The Sadies are indeed the day; their supporting vocals hum, bing, and jive with a lithe, limber quality to perfectly complement Williams' expletives. In fact it's The Sadies' vocals that add so much frank fun to the single "I Gotta Get Shorty Out of Jail," transforming Andre's violent promises into a song full of funk and sass.
The music is a rich medley of folk, including slow blues waltzes ("I Thank God"), gospel touches, and quick country fiddling blending with rock ("I'll Do Most Anything for Your Love"). Sometimes Andre sings, sometimes he speaks, but whenever he vocalizes you can't help but listen. So before we move onto the new releases, remember to look back and appreciate what's come before; you might find something new – to you – out there.


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A performer in Bono's rock musical Spider-Man: Turn Off The Dark was left seriously injured on Thursday following an onstage accident.
Dancer Daniel Curry's leg became hooked in a stage trap door as the elaborate set was moved at the beginning of the second act at Broadway's Foxwoods Theatre.
Aides rushed to help and a hole was cut in the floor in a bid to release his limb. Curry, 23, who plays one of nine Spider-Man dancers in the show, was then carried out on a stretcher and taken to Bellevue Hospital in New York. The performance was immediately cancelled.
Audience member Melissa Kessler tells the New York Times, "The floor looked completely closed on his leg… A stretcher was brought out, they were using a saw to cut a hole in the stage floor. All we cared about was whether the actor was and would be O.K."
No further details of his condition were available as WENN went to press.
It is the latest in a long line of accidents which have blighted the highly technical show.
Performer Christopher Tierney narrowly cheated death when he fell from an onstage platform in 2010, and subsequently underwent treatment for injuries including broken ribs, a fractured elbow, a bruised lung, three fractured vertebrae and a cracked skull, while he also endured back surgery and months of subsequent rehabilitation treatment.
The musical features a score by U2 stars Bono and The Edge.
A performer in Bono's rock musical Spider-Man: Turn Off The Dark was left seriously injured on Thursday following an onstage accident.


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It's Your Day Star Card
Learn how to make this birthday card using these free instructions. Handmade cards are the perfect way to show you care, and with these card-making steps, creating this design is easy.
SUPPLIES: Cardstock: (white) Neenah Paper; (yellow) Bazzill Basics Paper Clear stamp: (sentiment from It's Your Day set) Hero Arts Dye ink: (black) Hero Arts; (Broken China) Tim Holtz/Ranger Industries Watermark ink: Tsukineko Embossing powder: (clear) Hero Arts Finish: (dimensional glaze) Ranger Industries Tool: (border punch) EK Success Finished size: 5 1/2" x 4 1/4"
1 Make card from cardstock. 2 Sprinkle water on cardstock. 3 Quickly add embossing powder to wet cardstock and emboss. 4 Ink embossed panel. Note: Wipe off excess ink from embossed portions. 5 Adhere panel to card. 6 Stamp sentiment on cardstock; trim. 7 Adhere stamped panel to cardstock with foam tape. Trim panel and adhere to card. 8 Border-punch cardstock. Apply dimensional glaze to punched stars and adhere to card. Note: Adhere some stars with foam tape.
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The Girvan Methodist church is situated in the centre of Girvan. click here for location map
The Sunday service is held at 11:00 except for joint services which are at 10:30 - see the Circuit Plan for details.
There is also a weekly lunchtime Shoppers' Service on Wednesdays at 12:30. We start with tea and a snack, with informal worship at 13:00
Notes about the location map links
These links direct you to a mapping site and show a map of the relevant area. The actual location is shown on the map by an arrow. You can either zoom in for more detail or zoom out to see the general area. The arrow should stay in the correct place.
Girvan Methodist Church is a Charity – No. SC038086


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I hope everyone had a great weekend. Ours was fun and too short as always!
As promised I'm back finally with pics of our tweaked bookcases, and guess what…they have books on them, lots of them. I'm digging the cute little seating area we've got going on now in our bedroom, in between the bookcases. You can sit down grab a book and chillax, all in the little corner of our room.
Bryan usually makes fun of me because we have more "stuff" on the shelves then books. But not this time. All our hardcover and paperback books are living happily together in one spot. Who says all your books have to be great looking hardcover books to look great out in the open, not this girl. Right now my trashy beach reads are living at home with Bronte and Hardy, comingling nicely together.
Below is where we left off last time. The bookcases weren't looking terrible before but it was about time I switched up what was on them, moved some stuff around and took the rest of our books that were collecting dust up in the attic and placed them on shelves where they belong.
Of course there was A LOT of mess making before I got it all back together. Whenever I want to completely change something around I take everything completely down off the shelves and start from scratch. I've always found that if I don't do this a couple things happen. I will get bored/distracted br something shiny and never finish or it ends up looking very similar to where I started. Taking everything down gives me a chance at a clean slate and not to mention a chance to get at all those dust bunnies that tend to accumulate in every nook and cranny.
Of course it doesn't come without a down side, that being the giant mess of books and stuff everywhere.
One I had everything off the shelves I loosely sorted out the books by subject and started placing everything back on the shelves, then standing back and looking, placing some more things on the shelves and stepping back again.
Eventually I got it the way I was mostly happy with it left it alone for a while then came back and tweaked again over the next few days.
Now most of my summer reads are at home on the shelf above our collection of vintage Popular Mechanics Do-It-Yourself library from Bryan's Dad. All My Home Decorating Books now live on the top shelf. Along with our brass fish.
Admittedly I've also amassed quite the collection of James Patterson Books on the top shelf. All our beach tags from summers past live in the vase along with some found beach glass.
Bryan's collection of survival type zombie books hang out on the bottom shelf.
I think I'll sit down grab a book and a cup of coffee and stay awhile.


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- Spring Arts Collective Logo by Stu Moskowitz
Spring Art Collective (SAC) is the name of a program which offers fine art and music classes to interested young people. This year's program, held at the Mateel Community Center in Redway, began March 1, 2013 and will run through April 26, with a requested $5 donation per class session.
Click here for more information on the program.
Use the player below to hear more on this story, which was aired on the KMUD Local News, Monday, March 4, 2013 by KMUD News Director, Terri Klemetson.
Photos below from the SAC: student paintings on silk, drying (left) and to the right, Kathryn Guillette with SAC music students.
According to a press release from the Humboldt County Sheriff's Office, dated Fri., March 1, 2013:
On 03-01-2013, approximately 12:15 p.m. the Humboldt County Sheriff's Office was notified by a citizen that they located a male, believed to be missing person Jeffrey Panutsos in the woods near Redwood Fields, deceased. Deputies responded to the scene and the Humboldt County Coroners Office was notified. It appeared that Panutsos injuries were self inflicted.
The original post of this incident appears below.
According to a press release from the Humboldt County Sheriff's Office, dated Feb. 28, 2013:
On 2-27-13 at about 1000 hours, the Humboldt County Sheriff's Office received a call from a concerned relative of Jeffrey Panutsos reporting him as a missing person. The relative informed the sheriff's office he was last seen on 2-26-13 at about 2:00 p.m. when he left for a walk in the 3200 block of Cedar Street, Eureka. The sheriff's office also learned that Panutsos frequently walks in the areas of Redwood Fields, Sequoia Park and other forested areas surrounding these locations. The relative is concerned because he suffers from unspecified medical conditions and for him to be gone overnight is unusual.
The sheriff's office is asking the public's help in locating Panutsos. Panutsos is described as a white male age 20, 6'2, 175-180 lbs., blond hair and green eyes. Panutsos was last seen wearing a green sweatshirt with "Humboldt" printed on the front, blue jeans, dark colored vans and a black beanie cap.
Panutsos has been entered in the state missing persons' database and other local law enforcement agencies have been alerted. Anyone with information is asked to contact the Humboldt County Sheriff's Office at 707-445-7251 or the Sheriff's Tip Line 707-268-2539.
Update- Thurs., Feb. 28, 2013; wanted suspect, Walter Kristopher Miller, arrested in Ukiah. Hear more on the KMUD Local News tonight at 6 PM.
According to a press release from the Mendocino County Sheriff's Office, Walter Kristopher Miller has been arrested. Miller is a suspect in a vehicular pursuit which, according to a Sheriff's Report, included gunshots fired by Miller at the pursing officer's car. Miller was taken into custody on Wed., Feb. 27 and booked for: attempted murder, illegal possessing a firearm, burglary, possessing stolen property, conspiracy and parole violation. See the press release directly below for more information on the arrest of Miller. Also, check below for previous audio aired on this story and additional press releases.
Press release update:
On 02-27-2013 at approximately 1130 hours Sheriff's Detectives received information that Walter Kristopher Miller was possibly occupying a room at the Best Western Orchard Inn in the city of Ukiah. Sheriff's Detectives conducted investigations into the information while members of the Mendocino Major Crimes Task Force and County of Mendocino Marijuana Eradication Team established surveillance on the hotel. Approximately 2 hours later Sheriff's Detectives uncovered substantial information that showed Miller was currently occupying a room at the hotel.
A perimeter was established around the hotel with the assistance of personnel from the Mendocino County Sheriff's Office, Ukiah Police Department, California Highway Patrol (officers and helicopter) and Mendocino County District Attorney's Office.
The Mendocino County Sheriff's Office SWAT team, comprised of personnel from the Mendocino County Sheriff's Office and Willits Police Department, were summoned to the scene. The SWAT team was deployed to the inside of the hotel where the team then confined Miller to the room he was solely occupying on the second story. Customers inside the hotel were evacuated to a safe location away from the hotel and nearby businesses were instructed to shelter in place. The City of Ukiah Fire Department in addition to the City of Ukiah Ambulance service and Ukiah Ambulance service were summoned to the area to stand by in the event of a medical emergency.
Personnel from the Mendocino County Sheriff's Office Crisis Negotiation Team were summoned to the hotel in an attempt to contact Miller. Prior to their arrival a Sheriff's Detective established telephone communications with Miller and began to negotiate his peaceful surrender. During the approximately 2.5 hour negotiation process Miller expressed a desire to surrender to his parole agent from the Division of Adult Parole Operations with the California Department of Corrections and Rehabilitation. As the parole agent was arriving at the hotel Miller exited the room and surrendered himself to members of the SWAT team.
Sheriff's Detectives conducted a search of the hotel room pursuant to a search warrant and seized an AP 9mm machine pistol with 2 loaded high capacity magazines (20 & 30 round magazine). Sheriff's Detectives noted this was one of the firearms stolen from the Van Arsdale Road residence in Potter Valley on 02-25-2013 and was the firearm believed to be used during the attempted murder of the Mendocino County Sheriff's Deputy on that same day.
Miller was transported to the Mendocino County Jail where he was booked on charges of attempted murder, illegal possessing a firearm, burglary, possessing stolen property, conspiracy and parole violation. Miller is currently being held on a no bail status.
The original post of this story appears below.
A high speed pursuit, with shots fired at the pursuing Mendocino Sheriff Deputy's vehicle, occurred last Mon.evening. One of the two suspects in the incident has been arrested, but the other suspect, Walter Kristopher Miller, age 33, from Ukiah, California, is still at large and is considered armed and dangerous,
Use the player below to hear more on this incident, including press conference audio from Mendocino County Sheriff Tom Allman. This story was aired by KMUD News Director, Terri Klemetson, on the KMUD Local News Tues., Feb. 26, 2013.
Below, see the photo of wanted suspect Miller, arrested suspect Christopher Skaggs, and the Mendocino Sheriff's Office press releases.
Wanted suspect, Walter Kristopher Miller, shown below:
Arrested suspect, Christopher Skaggs, is shown below.
Original press release, dated Mon.,Feb. 25, 2013:
On 02-25-2013 at 2149 hours a Mendocino County Sheriff's Deputy conducted a traffic stop of a sedan displaying an expired registration in the 1200 block of South State Street in Ukiah, California. Once the sedan stopped the Deputy approached the driver?s window to contact the driver. Upon reaching the window the vehicle quickly accelerated southbound on South State Street, which prompted the Deputy to give chase.
The Deputy engaged the sedan in a vehicular pursuit as the sedan reached speeds of approximately 80-90 miles an hour. The sedan shortly thereafter turned westbound on Highway 253 and slowed to speeds of approximately 50-60 miles an hour. At this time the sedan swerved into the opposing traffic lane several times, even in the presence of blind curves in the roadway In the 900 block of Highway 253 the front passenger of the sedan partially exited the open passenger window and shot several times at the Deputy's patrol vehicle with a handgun. One of the bullets struck the patrol vehicle's radiator and shortly thereafter rendered the patrol vehicle inoperable.
Mendocino County Sheriff's Deputies from county-wide converged to the area in an attempt to locate the sedan that was last seen traveling westbound of Highway 253. At this time the search was aided by personnel from the California Highway Patrol, Ukiah Police Department, Cloverdale Police Department and Sonoma County Sheriff's Office.
During the search the sedan was found abandoned in a driveway leading to a residence located in the 6000 block of Highway 253. As a result, a reverse 911 call was initiated to residents in the surrounding area. During a search of the driveway near the sedan several items where found that showed the escape path, by foot, of the suspects. Deputies on scene noticed the items found were reported as being stolen from a residential burglary on Van Arsdale Road in Potter Valley earlier in the evening. It was noted by Deputies that several firearms (handguns, rifle and shotgun) and ammunition had been stolen during the residential burglary but had not been recovered with the abandoned sedan.
Sheriff's Detectives responded to the scene and are conducting further investigations into the shooting incident.
At this time Detectives have identified Christopher Skaggs (30-years-old from Redwood Valley, California) and Walter Kristopher Miller (33-year-old from Ukiah, California) as persons of interest in this incident. The public should consider Skaggs and Miller to be possibly armed and dangerous. Skaggs is currently wanted on an unrelated burglary and robbery incident reported to the Sheriff's Office on 02-19-2013.
Anyone with information on the current whereabouts of Skaggs and Miller are urged to contact the Sheriff's Office Dispatch Center at 707-463-4086 or the Sheriff's Office Tip-Line at 707-234-2100.
Updated press release- Tues., Feb. 26, 2013:
On 02-26-2013 at approximately 0900 hours Sheriff's Detectives received information that Christopher Skaggs was seen walking in the 3000 block of South State Street in Ukiah. Sheriff's Detectives responded to the area and saw Skaggs near the intersection of South State Street and Norgard Lane. When Sheriff's Detectives attempted to contact Skaggs he fled on foot and was subsequently apprehended after a short foot chase.
Through further investigations Sheriff's Detectives have identified Walter Kristopher Miller as being the person whom discharged a firearm at the Sheriff's Deputy during the vehicular pursuit.
At this time Miller's current whereabouts are unknown and the public should consider him to be armed and dangerous. Sheriff's Detectives believe Miller to still be in possession of a firearm and he has a history of violent behavior.
A photograph of Miller can be found by accessing the Mendocino County Sheriff's Office website at www.mendocinosheriff.com and by selecting the "County's Most Wanted" link on the left side of the main page.
The Mendocino County Sheriff's Office would like to thank the California Highway Patrol, Ukiah Police Department, Cloverdale Police Department, Santa Rosa Police Department, Sonoma County Sheriff's Office, Mendocino County District Attorney's Office, California Department of Justice Forensic Bureau and U.S. Marshals Service for assisting in this investigation.
Anyone with information on the current whereabouts of Miller is urged to contact the Sheriff's Office Dispatch Center at 707-463-4086 or the Sheriff's Office Tip-Line at 707-234-2100.
According to KMUD News Director, Terri Klemetson:
"New research shows rat poisons killing 25 different animals in California. Scientists and environmental groups are putting pressure on agencies and manufacturers to stop distributing the second-generation anti-coagulents."
Use the player below to hear more about this issue in a story aired by Terri Klemetson on the KMUD Local News on Thurs., Feb 21, 2013.
Additional Resources:
Click here for more info from Center for Biological Diversity.
Info on the Lawsuit Launched to Protect Endangered California Fox, Other Wildlife From Rat Poisons.
EPA Limits Most Toxic Rat Poisons in Homes But Still Leaves Wildlife at Risk
SF Gate article on the rodenticide issue
Previous KMUD News Posts:
Greenleaf Power, the current owner of the Eel River Power plant in Scotia, Calif., is a California-based company which describes itself on its web page as: "...committed to providing reliable green power for North America." The Eel River Power plant in Scotia has been in temporary shut down since Oct., 2012 but is scheduled to reopen in May.
Use the player below to hear interviews and more details related to the Eel River Power Plant, Geenleaf Power, biomass power production, pollution issues and more. This story was aired on Wed. Feb. 20, 2013 by KMUD News Director, Terri Klemetson.
Additional Resources:
Greenleaf Power-click for website
Eel River Plant - Scotia
Rewood Coast Energy Authority-website
Final Comprehensive Action Plan for Energy (CAPE)
Repower Humboldt-A Strategic Plan for Renewable Energy Security and Prosperity;links to documents
The Eel River plant is based in California's North Coast region about 30 miles south of Eureka. The plant was built in 1988 with Greenleaf Power taking ownership in 2010. See photos below:
Update: Thurs., Feb. 28, 2013- David Anthony Williams located.
According to a press release from the Arcata Police Department, dated Fri., February 28, 2013, David Anthony Williams, who was reported missing by a family member on February 21st, has been located after admitting himself to a local medical facility. For more information see the press release update below. The original post on this story can also be viewed below.
Updated press release:
On Tuesday, February 27, 2013 the Arcata Police Department was notified David Anthony Williams, age 53, had been located after admitting himself to a local medical facility. Williams was reported missing by a family member on February 21st.
The Arcata Police Department would like to thank all those who assisted in the search for Mr. Williams.
See the original post below.
According to a press release from the Arcata Police Department, dated Fri., February 22, 2013:
The Arcata Police Department is seeking assistance in locating David Anthony Williams, age 53. Williams and his wife were in town visiting family in Arcata on Thurs., Feb. 21 when he went for a walk at about 11:00am. Williams told family he was walking to the northtown area to get something to eat. He did not return. Williams was reported missing by a family member later that evening. He has a history of mental health issues and is considered at risk.
Anyone who has seen Mr. Williams or has any information as to his whereabouts is asked to call the Arcata Police Department at (707)822-2428.
Williams is described as a white male adult, 6'-2" tall, weighing 150 lbs with short brown hair and blue eyes. He wears glasses.
According to a press release from the Cailfornia Department of Fish and Wildlife, dated Feb., 21, 2013:
The California Department of Fish and Wildlife (CDFW) is announcing several changes to recreational groundfish regulations that apply to state waters, zero to three miles from shore. The new recreational regulations were adopted by the Fish and Game Commission and will take effect on March 1, 2013. "Department staff worked closely with the public for more than four years to implement this change," said Marci Yaremko, State/Federal Fisheries Program Manager. "Allowing retention of shelf rockfish inside the CCAs when the groundfish season is open will reduce discarding without impacting cowcod. It also simplifies regulations by allowing shelf rockfish take and retention both inside and outside the CCAs." Additionally, anglers will now have the ability to retain shelf rockfish while fishing inside the Cowcod Conservation Areas (CCAs) in waters shallower than 20 fathoms. Take and possession of bronzespotted rockfish, canary rockfish, cowcod and yelloweye rockfish will remain prohibited statewide.
Other changes to regulations pertain to bocaccio rockfish and include:
- An increase in the sub-bag limit to three fish within the 10-fish Rockfish, Cabezon, Greenling (RCG) complex bag limit.
- Removal of the minimum size limit and fillet length limit.
The open season dates and allowable fishing depths for the recreational Groundfish Management Areas are as follows:
- Northern – open May 15 through Oct. 31, in 20 fathoms (120 feet) or less.
- Mendocino - open May 15 through Labor Day, in 20 fathoms (120 feet) or less.
- San Francisco - open June 1 through Dec. 31, in 30 fathoms (180 feet) or less.
- Central- open May 1 through Dec. 31, in 40 fathoms (240 feet) or less.
- Southern – open March 1 through Dec. 31, in 50 fathoms (300 feet) or less.
For more information about recreational groundfish regulations and to stay informed of inseason changes, please call the Recreational Groundfish Hotline at (831) 649-2801 or check the CDFW Marine Region website at http://www.dfg.ca.gov/marine.
Additional Resources:
According to a press release from the Humboldt County Sheriff's Office, dated Feb. 17, 2013:
On 02-17-2013, at approximately 1:00 a.m. the Humboldt County Sheriff's Office received a 911 call from a citizen who reported three males were at a large party in the area of East Ferry Road, Ferndale and were assaulting several people. Sheriff's Deputies, California Highway Patrol Officers and Ferndale Police responded to the scene. While deputies were enroute they were advised the three male suspects were attempting to leave the area in a dark colored KIA Rio. A Ferndale Police Officer spotted the SUV near Fernbridge and stopped it. Deputies and CHP Officers joined the Ferndale Officer and detained the three males who were in the Kia. The officers saw the occupants had fresh injuries to them and showed signs of alcohol intoxication. The officers could also see open alcoholic containers in the vehicle. All three subjects identified as Douglas Wayne Flowers, 43 years old, from Fortuna and Curtis Flowers, 22 years old, from Fortuna and Christopher James Hanly, 23 years old from McKinleyville were detained. Douglas Flowers is the father of Curtis Flowers. Curtis was the driver of the KIA Rio. Medical was requested to respond to the scene and treat them for their injuries.
Deputies then contacted witness and the victims. They were told by the witness and victims that the Flowers and Hanly showed up at the party on the Ferndale River bar intoxicated. The suspects shouted "White Pride", as they walked around through the crowd. They were asked to calm down by party attendees. Curtis Flowers started pushing people and challenging them to fight. An 18 year old female attempted to leave the party in a Toyota Pickup truck because of Curtis Flowers behavior. As she got into the truck Curtis Flowers walked up to the truck and swung the truck door open. In doing so the door struck another 18 year old female who was watching what was occurring and standing near the pickup truck. When the female who was struck by the door made a comment about being struck by the door to Curtis Flowers, he punched her in the face with a closed fist. When the injured female got back up Douglas Flowers then punched her in the face knocking her back to the ground. The female immediately fell to the ground a second time. Meantime the female who had been in the truck exited the truck to assist the assaulted and injured female and she was punched in the face, which knocked her to the ground and unconscious. A 16 year old male who was close by came to both females aid and was punched in the eye by Curtis Flowers. Then all three suspects Curtis Flowers, Douglas Flowers and Hanly began punching him in the face after knocking the 16 year old to the ground.
Deputies could see the sixteen year old's eye was swollen almost shut. One of the eighteen year old females received a broken jaw which required surgery at a local hospital. The other female refused medical attention.
Curtis Flowers was transported by ambulance to Redwood Memorial Hospital to be treated for a cut on his neck and was admitted, however he fled from the hospital on 2-17-2013 around 5:00 p.m. Fortuna Police checked the area for him and were unable to locate him. Curtis Flowers is on active State Parole for a conviction of Assault with a Deadly Weapon. Curtis is wanted for Assault Causing Great Bodily Injury, Driving under the Influence, Assault and Battery, and Violation Parole. A Be-on-The-Lookout was broadcast to local Law Enforcement.
Douglas Flowers and Hanly were both arrested and booked into the Humboldt County Correctional Facility. Douglas Flowers was booked for Assault Causing Great Bodily Injury and Public Intoxication. His bail was set at $50,000.00. Hanly was booked for Assault, Probation Violation and Public Intoxication and was released on his own recognizance.
The Sheriff's Office will be increasing patrols in the Eel River area for the foreseeable future to help curtail parties and other criminal activity.
Anyone with information for the Sheriffs Office regarding this case or related criminal activity is encouraged to call the Sheriffs Office at 707-445-7251 or the Sheriffs Office Crime Tip line at 707-268-2539.
Wanted suspect, Curtis Flowers:
Update - Wed., Feb. 20, 2013:
According to an update from the California Correctional Center, James Robert Prinz who walked away from the High Rock Conservation Camp near Weott on Mon., Feb. 18, 2013, was apprehended, without incident, a day later in Fortuna. The press release update appears below.
Minimum security inmate James Robert Prinz, walked away from the High Rock Conservation Camp CC# 32 in Weott, California on February 18, 2013. Inmate Prinz was apprehended in Fortuna, California by Fortuna Police Department at approximately 3:15 p.m. on February 19, 2013, without incident. Special agents from the California Department of Corrections and Rehabilitation transported Inmate Prinz to the California Correctional Center in Susanville, California. Inmate Prinz was committed to the California Department of Corrections and Rehabilitation for Criminal Threat to Cause Great Bodily Injury, Resisting an Officer with Force and Violence and Battery on a Peace Officer from Placer County. He was scheduled to be paroled in April 2013. This matter will be referred to the Humboldt County District Attorney's Office for prosecution.
Of all offenders who have escaped from an adult institution, camp or community-based program since 1977, 99.1 percent have been apprehended.
The original post on this incident may be viewed below.
According to a press release from the California Correctional Center, dated Feb. 19, 2013:
A Minimum security inmate walked away from High Rock Conservation Camp which is located just outside Weott, California on February 18, 2013.
The walkaway, 43 year old James Robert Prinz, is described as a White male, 200 pounds, with blue eyes, short brown hair and medium complexion. He stands approximately 6'2" tall with a medium build. He was last seen wearing orange pants with "C.D.C. R. Prisoner" written on them.
Prinz was committed to the California Department of Corrections and Rehabilitation on April 21, 2011, from Placer County for Criminal Threat to Cause Great Bodily Injury, Resist Officer with Force and Violence and Battery on a Peace Officer. He was scheduled to be paroled in April 2013. He was last seen approximately 3:30 p.m. this afternoon. Escape apprehension efforts are continuing. Anyone seeing him should contact 9-1-1 or law enforcement authorities immediately.
Additional Contact Information:
Anyone having information about or knowledge of the location of James Robert Prinz should contact the California Correctional Center Watch Commander at (530) 257-2181 extension 4173.
James Robert Prinz, shown below:
KMUD News has been following the recent flurry of criticism surrounding Green Diamond Resource Company's logging practices, including their timber harvest plan for the Strawberry Rock area near Trinidad, California. Recently Green Diamond hosted a public meeting to discuss their current plans, and KMUD covered the event.
Use the player below to hear more on this story, including a report from KMUD News Correspondent Eric Black. This audio includes coverage of the meeting held by Green Diamond on Wed., Feb. 13, at the Bayside Grange, updating the public on Green Diamond's current plans. This story was aired by KMUD News Cordinator, Christina Aanestad, on the KMUD Local News, Feb., 14, 2013.
Click here for a map showing the location of Strawberry Rock.


text:
Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01591902
Recruitment Status : Terminated
First Posted : May 4, 2012
Last Update Posted : September 11, 2018
- Study Details
- Tabular View
- Results Submitted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Diabetic Retinopathy HIV
|Drug: Tesamorelin Drug: Placebo-Control
|Phase 4
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|129 participants
|Intervention Model:
|Parallel Assignment
|Double (Investigator, Outcomes Assessor)
|Primary Purpose:
|Official Title:
|A Prospective, Randomized, Placebo-controlled, Double-blind Clinical Trial to Evaluate Whether EGRIFTA® (Tesamorelin for Injection), 2 mg Once Daily SC, Increases the Risk of Development or Progression of Diabetic Retinopathy When Administered to HIV-infected Subjects With Abdominal Lipohypertrophy and Concomitant Diabetes
|Actual Study Start Date :
|June 2012
|Actual Primary Completion Date :
|May 2018
|Actual Study Completion Date :
|August 2018
Experimental: EGRIFTA Treatment Grop
Sterile, lyophilized, nonpyrogenic powder containing tesamorelin acetate with mannitol as excipient
Drug: Tesamorelin
Daily 2 mg subcutaneous injections of tesamorelin
Placebo Comparator: Placebo
Drug: Placebo-Control
3.0 mL vials
- Difference in percentages of subjects with a 3-step or greater progression (from both eyes) on the Early Treatment Diabetic Retinopathy Study (ETDRS) PERSON scale. [ Time Frame: 3 years ]Subjects will undergo an opthamologic examination including fundus photographs at 3 month intervals for duration of 36 months
- Change from baseline in HbA1c by intensification of concomitant diabetic treatment [ Time Frame: 3 years ]HbA1c values will be obtained at screening at month 3, 6, 12, 18, 24, 30 and 36
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion criteria:
- Subject has given written informed consent and is willing to comply with the requirements of the protocol;
- Subject is an adult man or woman (≥ 18 years old);
- Subject has laboratory confirmed HIV infection;
- Subject is receiving ART that has been stable for at least 8 weeks prior to screening;
- Subject has physical evidence of abdominal lipohypertrophy, as determined by the examining study physician;
Subject has T2DM as determined by previous HbA1c ≥ 6.5%, previous fasting plasma glucose
- ≥ 126 mg/dL (7.0 mmol/L), and/or previous 2-hour plasma glucose ≥ 200 mg/dL (11.1 mmol/L) during oral glucose tolerance testing (OGTT), and/or previous random plasma glucose ≥ 200 mg/dL (11.1 mmol/L) with symptoms of uncontrolled DM;
- if subject has been diagnosed with T2DM and is on glucose lowering medications for greater than 1 year the above glucose parameters do not apply;
- Subject, at the time of screening, has HbA1c between 6.0% and 12.0%;
- Subject's diabetes has been treated for at least 1 year by diet alone, individuals who are on a stable dose (at least 3 months) of insulin, an OHA, or a GLP-1 analogue plus insulin to control diabetes are permitted if their HbA1C is below 6.0%. OHA, GLP-1 analogue, or OHA/GLP-1 analogue plus insulin according to current American Diabetes Association (ADA) guidelines, and doses have been stable for at least 3 months;
- If the subject is using lipid lowering drugs, the dose must be stable for at least 2 months prior to screening;
- Subject must have an electrocardiogram (ECG) without clinically significant abnormalities within 6 months prior to screening;
- Pre-menopausal women of childbearing potential are eligible only if they are not pregnant (negative urine pregnancy tests at screening and baseline) or lactating and are using an acceptable form of birth control prior to study entry and for at least 2 months after completing treatment. Acceptable contraception is defined as two barrier methods, or one barrier method with a spermicide, or an intrauterine device, or an oral contraceptive;
- Women of non-childbearing potential must be post-menopausal (no menses for more than 1 year) or surgically sterile (tubal ligation or hysterectomy);
- Women over 40 years old must have a negative mammogram within 6 months prior to screening or a mammogram will be taken at screening;
- Men must have a normal prostate exam and a prostate specific antigen (PSA) Individuals who are on a stable dose (at least 3 months) of insulin, less than or equal to 5 ng/mL within 6 months prior to screening or PSA and, for men 50 years of age or older, a prostate specific antigen will be measured at screening
Exclusion Criteria:
- Subject has Type 1 DM;
- Subject has body mass index (BMI) < 18.5 kg.m2;
- Subject has or has had an opportunistic infection or acquired immune deficiency syndrome (AIDS)-defining illness within 3 months of screening;
- Subject has or has had a malignancy or, for women, personal or family (first degree relative) history of breast cancer. Exceptions are basal cell carcinoma, in situ carcinoma of the cervix, in situ anal carcinoma, treated and stable cutaneous squamous cell carcinoma. and stable Kaposi's sarcoma;
- Pre-existing PDR or severe non-PDR (NPDR), defined as an ETDRS level of ≥ 53 in either eye;
- Subject has or has had cytomegalovirus (CMV) retinitis, toxoplasmosis, or any other ocular infection that would prevent evaluation of DR;
- Subject has previously been treated for DR (treatments such as laser photocoagulation, intravitreal injection, or vitrectomy);
Subject has any of the following illnesses or conditions:
- hypopituitarism, history of pituitary tumor or pituitary surgery;
- untreated hypothyroidism;
- head irradiation or head trauma that has affected the somatotropic axis;
- uncontrolled hypertension, defined as systolic pressure > 140 mm Hg and diastolic pressure > 90 mm Hg;
- unstable CV condition, defined as:
i. acute MI; ii. unstable angina; iii. decompensated congestive heart failure (CHF, new onset or exacerbation); iv. stroke; v. history of any of the above within 6 months prior to screening; f. hepatic abnormality, defined as aspartate aminotransferase (AST) or alanine aminotransferase (ALT) > 3 times the upper limit of normal (3 x ULN); g. renal abnormality, defined as serum creatinine > 2 x ULN; h. lipid metabolism abnormality, defined as fasting triglycerides > 1500 mg/dL; i. anemia, defined as hemoglobin ≤ 7 g/dL;
Drug or hormone use as follows
- Men: change in regimen or supraphysiological dose of testosterone within 2 months prior to screening;
- anabolic steroids, GH, GH secretagogue, GHRF products or analogs (including EGRIFTA®), IGF-1, or IGF binding protein 3 (IGFBP 3) within 6 months prior to screening;
- Drug or alcohol dependence within 6 months prior to screening;
- Subject is using or has used anorectics, anorexigenics, or anti-obesity agents within 3 months prior to screening;
- Subject is pregnant or nursing;
- Other significant disease that, in the Investigator's opinion, would exclude the subject from the trial;
- Participation, within 30 days prior to screening, in another clinical trial of an investigational agent that could affect IGF-1 levels;
- Known hypersensitivity to the study drug treatments.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01591902
|Marilyn De Chantal
|Responsible Party:
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
|First Posted:
|May 4, 2012 Key Record Dates
|Last Update Posted:
|September 11, 2018
|Last Verified:
|September 2018
Retinal Diseases
Diabetic Retinopathy
Eye Diseases
Diabetic Angiopathies
Vascular Diseases
Cardiovascular Diseases
Diabetes Complications
Diabetes Mellitus
Endocrine System Diseases
Growth Hormone-Releasing Hormone
Growth Substances
Physiological Effects of Drugs
Hormones, Hormone Substitutes, and Hormone Antagonists


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LOVE the merging of several of the threads into one common thread! GREAT IDEA!!
I'm thinking that I'm sad because my last remaining grandparent is going to pass away in the next day or 2. :(
I love Outdoor Christmas Lights!!
"Christmas: it's not the giving, it's not the getting, it's the loving." - Garfield
I'm Admin of AllThingsChristmas Forum - Click Here to Message Me with questions or if you need help!
Sorry I wasn't specific...it's my grandmother. At this point, we are all praying for an end to her suffering, and her eternal life in Heaven. It's been awhile now, and we all believe she is ready. It's still very hard and sad.
I love Outdoor Christmas Lights!!
I pray Tink is well too.
I love Outdoor Christmas Lights!!
Sorry to hear about your grandmother Mike
I'm Dreaming of a White Christmas


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All nine middle schools offer comprehensive programs of study designed to meet state grade level and graduation
requirements. Additional evening and summer courses are available through the Alternative Education Program.
Harford County middle schools offer a wide and varied range of extracurricular and club related activities.
These can include experiences in music, drama, fine arts, publications, and areas of student interest. All
secondary schools maintain a website; you are encouraged to visit the site for specific school information.