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On July 18, 2019, an arsonist set the Kyoto Animation studio on fire injuring several people and leading to the loss of lives. Details on this unbelievable act are still developing.
Sentai Filmworks hopes to help the KyoAni team during this time of need and asks that you join us in this endeavor.
Update: 7/18/19 8:15am CST
Although the situation is still developing, it is clear that our friends at Kyoto Animation (KyoAni) have suffered greatly. In addition to the loss of life, many lives will be forever changed. Like all of you, we wanted to take action to help however we can. That is the purpose of this Gofundme effort. (https://www.gofundme.com/f/help-kyoani-heal)
We've known KyoAni through their many works that have inspired, influenced and entertained us over the years. They are true masters of their art and one of Japan's national treasures.
Your pledges and the funds we raise are intended to provide the most direct, meaningful assistance possible to the victims of this heartbreaking tragedy. We are coordinating with others in the Japanese anime industry within Japan to ensure that funds collected reach those in need. We will continue to provide updates as those details develop.
For now, I want to thank everyone for their kindness, generosity and support of this effort. The outpouring of pledges and messages of support has been tremendous. Please help us continue this effort.
John Ledford
Sentai Filmworks
To help KyoAni , please visit (https://www.gofundme.com/f/help-kyoani-heal) This is a fundraiser created by Sentai Filmworks
In this video are all of KyoAni's created animes
Witnesses say Shinji Aoba claimed he started deadly blaze over plagiarisation dispute
Article by TheGuardian.com
Japanese police have named a 41-year-old man suspected of carrying out an arson attack on an animation studio that killed 34 people. Witnesses said Shinji Aoba confessed to the massacre as he was arrested. He was allegedly overheard telling police he started the fire because the studio, Kyoto Animation, had copied his ideas and stolen his novel.
Were it not for the three-storey burnt-out building visible over the tops of the houses along the narrow backstreets of Rokujizo in the Fushimi Ward of Kyoto, it would be hard to believe the area was the scene of the biggest mass killing in Japan in living memory.
On Thursday, Aoba allegedly burst into the building carrying 40 litres of petrol and a bag full of hammers and knives and set fire it. In addition to the 34 studio staff who were killed in the blaze, 35 were injured.
A chalk outline on the ground where Aoba was found lying is just behind a police cordon blocking the streets leading to the studio, where young artists created anime that won fans across Japan and beyond. The narrow streets had made it difficult for the dozens of emergency vehicles to reach the building, according to witnesses.
Keiyu Hada, a high-school student, was walking past the studio on Thursday morning with his mother when he saw the studio ablaze.
"We were about 10 metres away, but the heat was so intense on my face it was unbearable. There were three people outside that I saw had come out of the building. They were on fire; their clothes and hair were burning," said Keiyu, whose family looks after and lives at the local Buddhist temple.
"After a while, I couldn't stand to look, so we went back to the temple. Some people from the neighbourhood came with us, they thought there might be another explosion."
There were firefighters at the scene but it took a further 10-15 minutes before more arrived with hoses, Keiyu said. "I wonder if they had been quicker more people could have been saved, but I think it was hard for them to drive down there."
Under grey skies on Friday, a steady stream of mourners stopped to lay flowers. Others simply put their hands together and made long, silent bows in the direction of the building's charred remains.
Shoumyou Oh, a 23-year-old from China, made the trip down on the bullet train from Tokyo, where he is studying Japanese, to pay his respects.
"Kyoto Animation's productions are very popular in China – I have known them since I was in junior high school. They make anime and stories that touch your heart. This news was trending top yesterday on Weibo, the Chinese Twitter," he said.
"I can't understand why someone would do this. I want to hear the reason from the criminal."
Shortly after, the police had named the man they have in custody in hospital as Aoba.
"He is badly burned on his hands, feet, chest and face; his hair has been burnt off. We are waiting for word from the doctors as to when we can question him," Hiroyuki Sakai, the deputy chief of the local Fushimi police station told the Guardian.
Sakai confirmed 19 bodies had been found on the third floor and the staircase leading to the roof, with some piled on top of others, suggesting they were scrambling to escape.
Fushimi Ward usually had a low crime rate, said Sakai, and there had not been a single murder there last year, though a woman fatally stabbed a man in March during a domestic dispute.
About 100 police and medical examiners are working on the KyoAni case. An investigation headquarters has been set up in a gym in the the Kyoto police training centre as the local station is too small to cope.
"Five autopsies were carried out today. The bodies of the victims are in different states, depending how and where they died," Sakai said.
"There will be more autopsies done in the coming days. Once everyone has been identified and the families informed, we will release the names of the victims."
The suspect has yet to be arrested or charged. If he is, prosecutors will almost certainly seek the death penalty.


text: Add to Cart Compare Quick view Jeff Beck RARE Guitar Shop Framed Litho Autographed MSRP: Now: $1,299.99 Was: Very rare Jeff Beck Guitar Shop framed litho. Signed and hand numbered by Jeff Beck. This has some marks on the litho from being originally shipped still looks great and a very cool piec to have. MSRP: Now: $1,299.99 Was: Add to Cart Compare Quick view

subset: commoncrawl


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Module Information
Course Delivery
|Delivery Type
|Delivery length / details
|3 hour practical per week
|Assessment Type
|Assessment length / details
|Semester Assessment
|Sci LAB exercise
|Semester Assessment
|4 lab reports - 15% each
|Semester Assessment
|Lab Diary
|Supplementary Assessment
|As determined by the Departmental Examination Board
Learning Outcomes
On completion of this module, students should be able to:
1. keep a laboratory diary
2. write laboratory reports using a word processing package
3. determine the causes and minimize the effect of experimental uncertainty
4. present a value of a physical measurement together with its associated error
5. use and appreciate the limitations of simple laboratory instruments
6. use Sci Lab to perform basic computational exercises in physics
7. apply the above skills to the performance of basic experiments in physics
Brief description
Introduction to computational physics using SciLab.
Basic error analysis.
Keeping laboratory diaries and writing reports.
Students will be expected to perform a selection of experiments allocated on a "round-robin" basis.
Module Skills
|Skills Type
|Skills details
|Application of Number
|In essence, physics is based on the use of mathematics and experimental physics on the manipulation of number. Application of number is a central part of this module
|Students will keep laboratory diaries and write reports on experiments
|Information Technology
|Mathematical modeling is depent on the use of computers. In the experimental physics, students use Excel and SciLab to analyse data and will be expected to word process their lab reports
|Problem solving
|This is developed in the computational physics side of the module. Students will attend weekly problem solving workshops.
|Research skills
|Students will be expected to research the background to experiments.
|Subject Specific Skills
|Design and performance of experiments. Analysis of experimental uncertainty.
|Team work
|Students will generally do experiments in groups of two and we would encourage co-operation in the solution of modeling problems
Reading ListGeneral Text
Nelkon, Michael. (1987.) Advanced level physics /Michael Nelkon, Philip Parker. 6th ed. Heinemann Educational Primo search Should Be Purchased
Tipler, Paul Allen (2004.) Physics for scientists and engineers /[Paul A. Tipler, Gene Mosca] 5th edition. W.H. Freeman Primo search
This module is at CQFW Level 4


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Gavilon Grain
Roachdale, IN
Location:Roachdale, IN
Cost per bushel:$2.50
DescriptionGavilon Grain's project site soil quality was very poor, driving up the cost of steel bins due to the required sub-surface construction. Our foundation design for hoop buildings is easily altered to accommodate soil quality. With a pre-harvest construction period and lower cost-per-bushel than steel bins, we recommended adding a 180' by 304' hoop building, which they are using to store beans. They were so pleased we are now building a hoop building for corn for them.
- Receiving system
- Above floor aeration
- Constructed on 1700 psf soil
- MaconFortress™
- MaconMaximizer™


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Illegal Police Detention Waiting for CDS Drug Dog Allows Criminal Defense Attorney David Putzi to Negotiate Dismissal of Charges in Anne Arundel District Court - Glen Burnie, Maryland
Client charged with CDS Possession of Cocaine and Marijuana after police approached our client's car parked at a McDonald's. Our client, when asked, refused to consent to the search of himself and his car. Police then, without cause, made our client wait for a CDS Drug Dog to arrive. The State dismissed all charges.


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Influence of different endodontic irrigants on the push-out bond strength of an epoxy-resin based sealer and newly introduced bioceramic sealer to root dentin: An in-vitro study
Article Type : Research Article
Author Details:
Volume : 7
Issue : 1
Online ISSN : 2393-9834
Print ISSN : 2320-7302
Article First Page : 9
Article End Page : 18
Aim: The present in-vitro study evaluated the influence of different organic and inorganic root canal irrigants used during chemomechanical preparation on the push-out bond strength of an Epoxy-resin based AH Plus sealer and a Bioceramic Endosequence BC sealer.
Materials and Methods: Eighty extracted permanent human mandibular single rooted premolar teeth were used and randomly assigned to four major groups [according to irrigation protocol using sodium hypochlorite (NaOCl) with MTAD (mixture of tetracycline, acid and detergent) or ethylenediaminetetraacetic acid (EDTA) or phosphoric acid or normal saline (NS) as control group]. The root canals were instrumented using rotary nickel-titanium Hyflex® CM file system to size 30/0.06 taper, at the working length, as final shaping and finishing file, following different irrigation protocols, as per group allocation. The samples were further subdivided into two groups, with ten samples each (n=10), based on endodontic sealer; roots were obturated with gutta-percha and test sealers (AH-Plus or Endosequence Bioceramic sealer). The teeth were decoronated and obtained samples of eighty obturated roots of eight groups were cut to obtain 2mm thick coronal root slices (10 root section in each group), using hard tissue microtome. Bond strength of sealers was then measured by subjecting each root section to a compressive load via Instron Universal testing machine. The data were tabulated and statistically analyzed using analysis of variance (ANOVA) and Tukey's HSD along with Bonferroni's post-hoc test and level of significance set at a p value<0> Results: The highest mean push-out bond strength of 5.38 MPa for AH Plus sealer was obtained in Group 2A followed by 3.94 MPa for Endosequence BC sealer (Group 2B), when phosphoric acid was used as chelating agent. However, mean bond strength of AH Plus sealer was significantly decreased (p<0> Conclusion: The Bioceramic based Endosequence BC sealer and gutta-percha core combination was not superior in push-out bond strength to AH Plus and gutta-percha core combination. Moreover, use of different organic and inorganic endodontic irrigants influenced the push-out bond strength of both the sealers.
Clinical Significance: In dynamic clinical situation, for longer functional viability of an endodontically treated tooth, adhesion of a sealer to root dentin is necessary to avoid its dislocation during tooth flexure and also even during operative procedures like post space preparation. Adequate measures should be undertaken while using different irrigation protocols bearing in mind that the canal irrigants used during chemomechanical preparation can affect root dentin surface, thereby influencing sealer adhesion.
Keywords: A-H plus sealer, Bioceramic Sealer, MTAD, Push-out bond Strength, Sodium Hypochlorite.
Doi No:-10.18231/j.jds.2019.003


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At KMP+ House of Mentoring we specialize in designing and implementing mentoring programmes. We offer full tailor-made programmes as well as sub-elements. We have therefore developed a range of courses and workshops tailored to enable companies to facilitate parts of their mentoring programmes themselves.
We also offer courses and workshops tailored to the individual, as well as online webinars.
Most of our open courses take place in our venue in Virum, but we also use external premises. In addition, we have the opportunity to complete all courses and workshops internal within the company, as well as tailor the courses according to company objectives. It is also possible to complete the courses as virtual workshops.
Overview of our courses, workshops and webinars
Mentor+Facilitator Accreditation & Licence
Date: On-going – see our course overview for specific dates
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Place: Kongevejen 155, 2830 Virum
The Mentor+Facilitator accreditation & licence is a 2 day course that gives you the skills and knowledge you need to train mentors and mentees yourself, reducing the cost of your organisation's mentoring programme whilst ensuring its quality.
Business+Mentor Training
Date: On-going – see our course overview for specific dates
Time: 9am – 4,00pm (all days)
Place: Kongevejen 155, 2830 Virum
The Business+Mentor training programme is a 2 day intensive and professional mentor training course for mentors, managers and project managers who wish to develop and increase their mentoring, leadership and talent development skills.
Sign up for our newsletter and receive
- News and inspiration in the fields of mentoring, leadership and talent development.
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For more information about our privacy policies read here.
When signing up for our newsletter you give your consent to receive the above listed information and offers. You can change your mind at any time by clicking the unsubscribe link in the footer of any newsletter you receive from us, or by contacting us at email@example.com. We will treat your information with confidentially.


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- Ideal for turning branches and twigs into nutrient-rich garden mulch
- Powerful 15 amp motor effectively chips and shreds branches up to 1.5-Inches thick.No Load Speed (rpm):4100 rpm
- Compact design with 6-inch wheels for easy portability; Sound power level: 113 dB
- Safety hopper with locking knob prevents the motor from operating when opened. Hopper Dimensions-2 x 5 inches. Wheel Size-6 inch
- ETL approved; Full 2-year warranty
- SPECIFICATIONS - This All Electric Corded Wood Chipper Shredder & Mulcher is designed w/ a durable Polypropylene body & all powerful 15-AMP 1800Watt 120VAC 60Hz Electric Belt Driven motor, capable of 1.57" (39mm) MAX Limb Chipping Capacity to 17:1 Reduction w/ a Speed of 4,100RPMs. Unlike gasoline powered chippers this electric wood chipper produces no smog & is quieter, making it ECO & USER FRIENDLY. Included are a set of Dual Edge Blades that are Reversible, giving longevity for extended use.
- EFFICIENT DESIGN & CAPABILITIES - The durable Polypropylene housing will not rust nor dent & protects the rotor assembly which consists of (2) Cutting Blades for maximum chipping capability. Our Wood Chipper is equipped w/ an easy instant start switch & a Overload Protection switch. Also included is a Supply Cable of 13.7" (0.35m/1.1') & transported easily w/ the (2) 6" Wheels giving great portability. We included a Sturdy Push Paddle, so you can safely feed material into the hopper.
- SAFETY & PROPER USE - Our Electric Wood Chippers are OSHA, RoHS, ISO: 9001, 14001, CNAS, SQC, IAF, CSA, EL, cETLus, Intertek GS Listed approved standards & certified, including cull quality tested. Always use the correct extension cord type/size for the distance of extension needed, refer to the owner's manual on page E2 for recommended instructions, also always connect Wood Chipper to a GFCI outlet. Landworks Wood Chippers are best suited for outdoor environments.
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- VERSATILE: Ideal for turning leaves, twigs, brush, and branches into nutrient-rich mulch ; Rated Voltage 120 V ~ 60 Hz
- POWERFUL: 15-amp motor effectively chips and shreds branches up to 1. 73-inches thick
- SAFETY: Safety hopper with locking knob prevents the motor from operating when opened
- PORTABLE: Compact design with 7-inch wheels for easy portability
- WE'VE GOT YOU COVERED! : Your new chipper is backed by the Snow Joe + Sun Joe Customer Promise. We will warrant new, powered products for two years from the date of purchase. NO QUESTIONS ASKED. Contact Snow Joe + Sun Joe customer support at 1-866-766-9563 for further assistance.
Are you finding a machine to mulch plants or tree branches? Here a list of best wood chipper shredders or wood chippers for you to consider in a minute.
Anyone at any time can require a wood chipper. Whether you're looking to take care of backyard garden waste, or you own a business, you will find a chipper can come in handy. However, as there are so many different chippers on the market, it can be challenging to determine which is going to be most suitable for your requirements.
If you're a homeowner with minimal garden waste, you may find that an electric or battery powered chipper can be all that you require. Typically, they can take care of small branches and twigs, creating bark chips that you can then distribute back onto your garden. Some also come with a shredder or mulcher function as well, making it easier to bag up for removal.
If you're a business owner, a farmer, or have a lot of garden waste to remove, a wood chipper powered by gas might be a better option for you. These typically have more grunt, can chip large branches, and can also shred and mulch as well. Once you've established your needs, you can then set about checking out these top-rated options below.
9. Sun Joe Electric Wood Chipper Shredder
If you like to dabble in a little gardening and yard clearing, then you will at some stage require a wood chipper. However, rather than go out and buy a sizeable gas-powered chipper with a significant amount of power, a smaller and more compact chipper might be all you require. This one from Sun Joe might tick all the boxes for your needs.
It's affordable, meaning more homeowners can afford to buy one, and it's suitable for small yards in need of a quick clean up. You can pick up a range of branches and twigs, put them into the chipper, then benefit from the resultant garden mulch that comes out the other side.
To chip and shred your garden waste, this wood chipper uses a powerful and robust 15-amp motor. It can tackle branches up to one-and-half-inches thick, before making short work of preparing it for garden mulch.
Aside from its undeniable power, this wood chipper is also very convenient for homeowners. It's very compact, comes on six-inch wheels to make it portable, and comes with a two-year warranty for peace of mind as well. Any homeowner will be more than happy with how well this chipper can deliver.
8. LawnMaster Electric Chipper Shredder
If you have a small garden, but it's overrun by twigs, branches, and general garden waste, it might be time to purchase this wood chipper and shredder from LawnMaster. Designed to cater to the homeowner with a small patch of land, you will be impressed by all the features this machine has to offer.
It's electric powered, which means you don't have to worry about the hassle of oils and fuels, and it's safe for the environment too. It runs on a 15-amp motor which tackles all manner of branches and twigs. While it can't shred or chip bamboo, it can handle softwood up to one-and-a-half inches in diameter, and hardwood slightly smaller. Whether you have spruce, pine, oak, or beech branches to shred, you will find this electrically powered chipper can deliver.
Aside from its power, there is also a lot else to love about this chipper. It comes with a collection bag to make removal of the shredded wood a breeze, and you can also use it to prepare garden mulch as well. It offers a ratio of 10:1 for mulch and makes the entire process seamless.
When it comes time to pack the chipper away, the eight-inch wheels will come in handy. Wheel the chipper into your garden shed and forget about it until next time.
7. GreatCircle Machinery Gas Powered Multi-Function Wood Chipper Shredder for Lawn and Garden
If an electrical-powered wood chipper is not enough to tackle your large yard, then this gas-powered alternative from GreatCircle Machinery might be. As a three-in-one unit, it's versatile enough to carry out a range of backyard tasks, while also being affordable enough for the average homeowner. There's nothing you won't love about this machine.
It comes with a top hopper if you intend on shredding and chipping a lot of wood at a time, as well as a side chute for smaller branches as well. What's more, it also comes equipped with an inlet for the shredding of leaves as well. There's very little this wood chipper can't tackle.
Because of its powerful 212cc engine, it's able to handle wood up to three inches in diameter without a problem, as well as various other wood items as well. The engine is CARB and EPA3 certified, it comes with a three-year warranty, and it's packed full of power and convenient features to see you tackle your yard clearing duties with gusto.
6. Snow Joe Electric Silent Wood Chipper Shredder
If you're an avid gardener with an eye for detail, then adding a wood chipper to your garden shed is a must. Not only can this one from Snow Joe help your yard look spick and span, but it can also help you to turn previously unusable garden waste into mulch that's rich in nutrients. Rather than throw it in the trash can, those leaves and twigs can become useful once more.
One of the standout features of this chipper is its engine. As it's electric, you can rest assured it will require minimal maintenance. It's eco-friendly, releases no emissions, and doesn't need you to deal with the hassle of fuels and oils as well.
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5. Tazz Chipper Shredder with 5 Year Warranty
If you're tired of buying low-quality outdoor power tools that keep breaking down, it might be time to upgrade to this wood chipper from Tazz. Rather than spend thousands of dollars replacing your shredders and various tools over time, you can instead rely on this one to last the distance.
It comes with a five-year warranty for all manufacturers faults, has a tough and robust 301cc Viper engine that will provide no end of power, and is suitable for both small and large yard clearing tasks. You are sure to find this wood chipper is all you need and more.
With its vacuum kit and expansive rotor, you can also rely on this wood chipper to produce more vacuum power than most other chippers on the market. While it's compact, it packs a punch.
However, aside from its power, there is also a lot of convenient features packed into this chipper. It comes with a debris bag you can unzip from the bottom for easy deposit, as well as a lock bag and connector. What's more, the 11-inch wheels are durable, won't go flat, and make portability from one job site to the next a breeze. You are sure to find this wood chipper from Tazz is a standout against its competition.
4. Powerhorse Chipper Shredder
Whether you're a homeowner, a farmer, or a professional, you will soon find that this wood chipper from Powerhorse will cater to all your needs well. Not only is it affordable, given its substantial gas engine and feature list, but it will provide years of faithful chipping service.
It comes with a robust 420cc gas engine, a cast iron sleeve to further reiterate its longevity, as well as engine protection in the form of a low-oil shutdown function. There's so much to love packed into one small engine.
What's more, this wood chipper is multi-functional. You can use it to either chip or shred branches – both of which will be suitable for the garden. Then, when you no longer require it, you can use its built-in handle with 13-inch pneumatic tires to transport it back to the garden shed. Take care of garden waste with confidence thanks to this wood chipper and shredder combination from Powerhorse.
3. Eco-Shredder Electric Chipper Shredder
With the changing of seasons, it's not uncommon for homeowners to require a wood chipper. After all, how else are you supposed to dispose of the many hundreds of sticks and branches, and the endless leaves? If your yard is looking a little worse for wear, but your garden could benefit from a pick-me-up, then this wood chipper is the answer.
Manufactured by Eco-Shredder, it's a chipper, shredder, and mulcher, all in one. With a powerful 14-amp motor, it can take care of brush, leaves, chips, and limbs, as long as they are all under 1.3 inches in diameter.
Even if you're not skilled in the use of outdoor power equipment, you will find this wood chipper is easy to use as well. Plug it in, turn it on, insert the wood and leaves and let the triple action cutting blades get to work. You can then remove the waste and scatter it over your garden. It even comes with extra cutting blades for user convenience, as well as being exceptionally portable and easy to store.
Everything about this wood chipper is designed to be convenient for the user. There's every reason to add it to your shopping list today.
2. YardBeast Wood Chipper
If you're a farmer or own a lifestyle block, there's every possibility you will require a wood chipper at some stage. After all, trees are often abundant on any agricultural block, and keeping them in check can take a lot of hard work. However, if you own a wood chipper such as this nine horsepower one from YardBeast, you will find the job goes far more effortlessly. Therefore, there's every reason to consider purchasing it today.
To help with its performance, this unit is kitted out with a V-belt transmission, a centrifugal clutch, and a robust Yamaha engine to power it all. It can take care of all manner of branches – from twigs through to substantial branches that are two-and-half-inches in diameter. What's more, it uses 14 foot-pounds of torque to deliver on this promise.
If you're a farmer, you will also enjoy how portable this wood chipper is. It comes with a trailer kit so you can attach it to your farm trailer, and even comes with gloves, safety glasses, and earplugs as well. As you should always put safety first, this is an exceptional deal on offer from YardBeast. If you're tired of a messy farm or lifestyle block, there's every reason to invest in this wood chipper today.
1. Worx Electric Leaf Mulcher Shredder
While this Worx electric leaf mulcher and shredder is not a wood chipper, it's still a convenient outdoor item many homeowners would be happy to own. As the changing of the seasons begins, and your yard becomes covered with leaves, there's every reason to invest in a leaf shredder.
Rather than put up with leaves rotting away and causing havoc in your yard, you can rake them up, then use them as mulch in the garden. While some wood chippers have a leaf shredding component, this leaf shredder is focused only on shredding leaves. With its 13-amp motor, it can mulch 53 gallons of leaves per minute into your choice of debris bags and uses high-quality bladeless systems to do it. What's more, it has a cutting diameter of 13 inches to ensure it can shred more leaves than most other shredders on the market.
When you purchase this leaf mulcher, be prepared to be impressed. It has a clean motor with a cooling system, it's easy to turn off and on, and it even comes with 24 cutting lines, a support ring for a bag, and a three-year warranty. You are sure to find this leaf mulcher ticks all the boxes for your backyard cleaning requirements.
Last update on 2020-07-27 / Affiliate links / Images from Amazon Product Advertising API


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The Henry B. Gonzalez Convention Center's number one priority is the health and safety of our guests, employees, and partners. We have taken proactive measures in response to this rapidly evolving situation and continually monitor information from various resources. Our team is ready to work with meeting planners to develop plans and procedures specific to each event. Find more COVID information.
Henry B. Gonzalez Convention Center
Henry B. González Convention Center
Phone: 210.207.8500
Mailing Address: PO Box 1809
San Antonio, TX 78296
Physical Address: 900 E. Market Street
San Antonio, Texas 78205


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By Gabe Teran, Operations Specialist, Youth Development Programs, Ventura County Office of Education
Gabe has worked in the field of adolescent alcohol and other drug prevention since 2003. He is a member of the Ventura County Rx Abuse & Heroin Workgroup and brings a focus on youth education and prevention. Ventura County Office of Education provided two secondary schools with support in Prescription Drug and Heroin prevention education measures. The Prescription Drug Media Campaign targeted high-school age youth, to impact awareness, prescription drug use and intended behaviors.
The Prescription Drug Pilot Project attempts to demonstrate changes in perception of harm, increased awareness of known risks, and associated levels of drug use. Parent brochures provide families with tips on identifying and understanding painkiller and heroin abuse.
> Download the PDF to read the full story
By accepting you will be accessing a service provided by a third-party external to https://venturacountyresponds.org/


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Next Episode of The Wrong Mans is
Based on the eponymous BBC Two series, The Wrong Mans follows two ordinary office workers who have their menial existence turned upside-down by a chance phone call and a case of mistaken identity: "If you are not here by 5 o'clock, we will kill your wife." As the only people who can help, these two unlikely characters must find their inner hero in their quest to save not just themselves, but their loved ones and ultimately their whole town.
Looks like something went completely wrong!
But don't worry - it can happen to the best of us,
- and it just happened to you.
Please try again later or contact us.


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Yearbook 5.01 (Air Date: 12/6/19)
The best of the best on the high school gridiron. Volleyball finals brought 5-set excitement and a surprise finish. Plus cross country, swimming, and the end of an era in tennis.
Minnesota Prep Spotlight 6.11 (Air Date: 11/10/19)
Check on football's defending champions and see how many made it to the semifinals. In volleyball, could Stewartville scratch the 5-year itch and bring a Title to southern Minnesota? Catch highlights from the biggest week of games ever.


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Free Postern Apk Latest Download For PC Full Version
Postern Apk Latest Download For PC Windows Full Version.Postern Apk Full Version Download for PC.Download Postern Apk Latest Version for PC,Laptop,Windows.With Postern, you can redefine your the behavior of all your devices' network traffic:
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SSH Tunnel
SOCKS5 Proxy
HTTPS/HTTP CONNECT method Tunnel
And it naturally can be used to by-pass Internet censorship(for Chinese users especially and in corporate networks that have firewalls to block you from certain sites), and a perfect tool to hide your IP address/identify.
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Visit our site for Postern tutorials and configuration samples : https://github.com/postern-overwal/postern-stuff
How to Run Postern Apk for PC,Laptop,Windows 7/8/10/XP
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Louppy-sur-Loison tourism and travel guide
Photo is of Verdun at 32 km from Louppy-sur-Loison
Visit Louppy-sur-Loison: highlights and tourist informationTo Visit Attractions
Louppy-sur-Loison is situated in the Meuse department and Lorraine region (now part of the Grand-Est region), in the north-east of France at 76 kilometres from Bar-le-Duc, the department capital (general information: Louppy-sur-Loison is 228 kilometres from Paris).
Popular places to visit nearby include Verdun at 32 km and Sedan at 41 km. For more places to visit and local tourist attractions see the map and listings below.
Louppy-sur-Loison, France: places to visit and attractions
Some of the places that we have visited and reviewed and can recommend when you are sightseeing close to Louppy-sur-Loison in Grand-Est.
Note that all distances below are 'direct' and real driving distances will be greater!
Map of places to visit near Louppy-sur-Loison
Markets in and near Louppy-sur-Loison
- Stenay: market Friday (13km)
- Longuyon: market Friday (18km)
- Longwy: market Thursday & Saturday (31km)
- Verdun: market Friday (32km)
- Piennes: market Thursday (34km)
- Sedan: market Wednesday & Saturday (40km)
- Villerupt: market Tuesday & Friday (42km)
- Audun-le-Tiche: market Saturday (44km)
- Vrigne-Aux-Bois: market Sunday (48km)
- Jarny: market Saturday (50km)
More information about Louppy-sur-Loison, Lorraine
Tourist attractions near Louppy-sur-Loison, France
What to do at Louppy-sur-Loison? Some places with official tourist classifications and other places of interest to visit nearby that should provide inspiration if you are visiting Louppy-sur-Loison.
Heritage sites
- Longwy ville neuve (Vauban fortifications) (31km)
Sites of natural beauty
- Lac de Bairon (42km)
Towns of Art and history
- Sedan (40km)
Geography and distances
Geographical Information
Commune: Louppy-sur-Loison
Canton: Montmédy
Arrondissement: Verdun
Department: Meuse
Region: Lorraine
New region: Grand-Est
Postcode: 55600
Distance to Louppy-sur-Loison
from Bar-le-Duc (prefecture): 76 km
from Paris: 228 km
from Calais: 300 km
from Nice: 655 km
from Bordeaux: 680 km
from Strasbourg: 199 km
Getting here
For driving distances to Louppy-sur-Loison from anywhere in France see driving distances and route planner.
We have 10 other places listed as being close (less than kilometres from ): Bazeilles-sur-Othain, Brandeville, Delut, Han-les-Juvigny, Ire-le-Sec, Jametz, Juvigny-sur-Loison, Quincy-Landzecourt, Remoiville and Vittarville.
This page in French: Visiter Louppy-sur-Loison


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Vidal Sassoon: Pro Series Color Protect Gloss (Review)
Product Summary:
This gloss color creme's rich moisturizing formula provides a veil of protection to help ensure the brilliant shine of your color treated hair. A professionally inspired formula for fashionably vibrant coloured hair. The best way to use this gloss is to either apply a dime sized amount onto towel-dried hair and comb through. Or you can apply some of the product on dry hair to finish your hair style. This product costs around $10.
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For the past few weeks I have dyed my hair quite a few times which comes to no surprise that I gravitated towards this type of product. I tend to use this more when it's the second or third day after washing my hair and I see that my hair looks dull. I definitely love using this product when my hair needs a little extra help. It adds shine and helps get me a nice finished look to my hair.
I am going to give this gloss 4.5 stars on 5. Truthfully, I don't have any complaints with this product. It adds shine and enhances the vibrancy of my hair color. It helps me finish my hair style and moisturizes my hair. The only thing I do have a problem with is the fact that this product is not cruelty free. If it was cruelty free I wouldn't have a problem giving it a perfect rating. Otherwise, this is a great product.
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Episode Description:
Synopsis of The humble Farmer TV show for December 27, 2015
You may be amazed when you read this email from Sherrie Benner in Gorham, Maine dated October 27, 2015: "I was watching channel 2 for my public service ad for my running for Gorham Town Council. I came across your show and I was mesmerized. You have a new fan. Loved the music and the personality. Sherrie Benner"
Thank you for looking at a program called "Real Maine Husbands, a Maine Reality Show."
56 minutes. This show includes 5.58 minutes of guitar virtuoso Denny Breau and Rayford Starks .
Although The humble Farmer is just as contrived as any reality show, here you will see no overweight people with tattoos pretending to repossess automobiles or emaciated wealthy models getting a massage. But don't give up. In this show you will see humble boiling lobsters that are dropped, alive, into the pot. You will learn the easiest and most efficient way of eating a lobster, which is cutting it apart with scissors. This is an educational show which, combined with the music in the background, makes it a program that will benefit any lobster lover who watches.
Well received in Northern New England as a radio show for 37 years, this is the same old fashioned music and humorous social commentary show that has delighted young and old alike every week since April 6, 1978 for radio --- and now for television.
Most of the video over the music is of humble buying lobsters, cooking them and eating them with his Canadian broadcasting friend, Phil Tilney. This is a show to be watched as well as be listened to. It is, and always has been, a radio show adapted for television.
Music is by: Clark Terry, Aaron Robinson, Gerry Mulligan, Paul Desmond, Ron Carter, Chet Baker, Stephane Grappelli, Coleman Hawkins, Rayford Starks and Denny Breau.
Tame fare, you say, for viewers expecting someone to be shot while stealing seaweed, arrested, attacked by protesting lobster lovers, or sink while paddling inside a 1,000 pound pumpkin.
The show is tightly scripted. It starts out with humble and Phil in down at the Marshall Point Light where Forrest Gump completed his cross country run. humble then visits his friend Dougie, at Dougie's Seafood place in Port Clyde and shocks watching tourists by littering. Phil and humble eat their lobsters at the humble farm. The show ends, as usual, with the Keystone Cops driving a car off the end of a dock.
The humorous and/or informative commentary that humble delivers between the songs is approximated below.
TV Rants December 27, 2015
1. What's going on with my body? Used to be I could feel an occasional bone sticking out of my chest. Now I can get my fingers in behind them. My friend Claire says I need to start eating at McDonald's.
2. I miss going to my exercise class. I was usually the only man there. For years I was in the front row at the exercise class, and I never knew what the 20 or so ladies were doing behind me. I never turned around to look and see. I do know that this exercise class is like most any other exercise class you are likely to see anywhere, because the tiny little bird like ladies who attend this exercise class religiously do not look anything like the ladies who really should be there. So --- you might well ask --- what motivates ladies to get out of a warm bed early, early in the morning and then show up at a building where they try to jump out of their skins for an hour? I'm going to tell you, because one morning, for the first time, I turned and looked over my shoulder --- and saw them passing around a small tin of chocolates.
3. Here's your humble Farmer weekly tip for health and happiness. My wife Marsha, The Almost Perfect Woman, just looked up from our neighbor's newspaper and said that the oldest man in the world had just died at the age of 115. Many of us would like to know his secret for a long and happy life --- so --- of course I asked Marsha to read more. She said, "He never married."
4. According to Dr. Addler, a psychologist at the college in Thomaston, many Knox County marriages that end in divorce could be saved. Addler suggests that men be content to let their wives be boss. If your wife wants to cook and clean and scrub, don't get in her way or argue with her. If it makes her happy, don't complain.
Young people don't seem to realize that anyone who's careful in selecting a mate can have an ideal marriage. Suppose that neither of you ever noticed that a wet towel or a wet water glass causes a white water stain on varnished surfaces. Perhaps you both drop your clothes beside the bed or in the bathroom and leave them there in a moldering pile for days. Or you each have a cat that walks on the kitchen counters with germ infested feet and eats out of your frying pan. Great! You and no one else should be married to each other.
On the other hand, suppose that each one of you knocks the other one down while rushing over to pick up a small raveling on the floor. You wouldn't be able to sleep if there was an unwashed dish in the sink. You'd have a wonderful marriage and would probably spend enjoyable hours grooming each other like monkeys.
Do not look in the personal column of the newspaper for a mate. It will give you the idea that everyone in the world wants to take moonlight walks on lonely beaches. A Port Clyde couple walked moonlight beaches for years before they discovered that they both hated it.
Which brings up the topic of Mutual Suffering, which is the basis for most of the successful marriages you see today. Let's say that you are going to buy a car that your wife doesn't want. The Mutual Suffering system allows her to buy furniture that you don't want to balance it out.
It works the same way with meals. If you have scallops for supper and she doesn't like them, she eats them without making a face or saying anything because the next night she gets back at you by serving pea soup which you hate.
With Mutual Suffering man and wife each get at least a piece of what they want. You want to shingle the roof because the rain leaks in, but she feels a kitchen stove is more important. You end up shingling half the roof and buying a second hand stove with only two burners that work. That makes it fair.
Sometimes Mutual Suffering works both ways at once. Suppose you're going bowling. You think she wants to go and she thinks you want to go. A week later you ask her to watch a Mel Gibson and the Body Snatchers video with you and she says, "But I went bowling with you last week." That's when you first discover that neither one of you wanted to go.
Then you have the situation where nobody owes anybody anything, so you both sit home and sulk and suffer nobly in silence while thinking, "We never go anywhere, we never do anything."
5. You know you're getting old when you're watching the TV advertisements for weight loss and the girl in the "before" picture looks a lot better than the skinny one.
6. You know people who drive new cars without health insurance. They will tell you that they can't afford health insurance. Only you can decide if they are daring or foolhardy. I feel safer with supplemental health insurance. It costs an arm and a leg, and, as I recall, when I pay it every month I have only $109 left over in my social security check. But within the past 100 days I have been flat on my back on an operating table twice. And have slept in a hospital bed two nights. Except for a couple of $100 aspirin, my insurance will probably take care of all of it, so I don't worry. But --- if I didn't have that supplemental insurance and were obligated to pay off those two operations, it would screw up my present plans to have the mortgage on our home paid off when I'm 84 so we can retire.
7. Haunted French pancakes give me the crêpes. England has no kidney bank, but it does have a Liverpool. Do you have friends who send you things like this? Have they really nothing better to do? I'm the humble farmer at gmail dot com.
8. Did I ever tell you about the time my friend Priscilla Adams went off to Mexico? When I asked her if she was going to get a hacienda, she said, "No, I plan to live alone."
These TV shows are now being posted on YouTube under Robert Karl Skoglund.
The radio version of this show now covers metropolitan New York City on WFDU.
Your viewers and I thank you for considering The humble Farmer. Have fun.
Episode Short Description: N/A
Downloads of This Episode: [SD File Downloads]: 16 [HD File Downloads]: 0 [Total File Downloads]: 16
[SD File Downloads]: 16
[HD File Downloads]: 0
[Total File Downloads]: 16
File Name of SD Episode: humble 2015 1227.mpg
Total SD Episode Video Runtime (hh:mm:ss): 00:55:59
File Size of SD Episode Video: 2,662,785,028 Bytes
Resolution of SD Episode Video: 720x480
Date SD Episode Video Uploaded: Monday, February 29, 2016 - 07:41
This episode has not been uploaded by the producer in HD format and is not available for download.
If you wish to have HD format, you can private message a request to the show's producer at The humble Farmer.


text: 110 Rolinata Drive, Riesel, TX – Virtual Tour Posted on October 23, 2013 by chasesager 0 Flares Filament.io 0 Flares × Click here to see more pictures and detailed information. Cute 2/1 in Riesel ISD! Charming home for first time home buyers or investors. Come check this out before its gone! Schedule a Showing Riesel Homes For Sale Search All Homes For Sale in Waco and Surrounding Communities Free List of Foreclosed Homes For Sale What is Your Home Worth? Homes Close to Where You Work Chase Sager Keller Williams Realty Waco 254-424-8766 Questions?Schedule a Showing! MLS#: 152120 Licensed In:Tx L2L Virtual Tours


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Goldin Peiser & Peiser LLP (GPP) of Dallas announced that Erick Cutler and Angela Walters have been admitted as equity partners.
"Over the years, Erick and Angie have demonstrated the leadership, motivation, people skills and financial expertise necessary to be strong firm leaders," says Allan Peiser, MP of GPP. "These traits, paired with their vision and true compassion for our team, make them both ideal candidates for equity partner. I am confident in their abilities, and I look forward to our growth and success as a result of their influence."
Cutler joined the GPP team in 2002 as a senior tax associate and was promoted to non-equity partner in 2006. He focuses on tax compliance and consulting work in the health care and real estate industries, where he oversees the preparation of all annual federal and state compliance and regularly reviews the client's financial statements.
Walters began her public accounting career in 1992 and joined GPP in 2013 as the director of accounting and consulting services. She is responsible for providing accounting, consulting and business advisory services to the firm's clients, as well as building a CFO advisory services practice within the accounting services group. The majority of her focus is on new business development strategy within the firm's key niche business – manufacturing and health care.


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Question about 2004 Audi A4
Posted by clenton on
Computer fault showing oil level sensor fault,how do I rest the fault if it is in fact a diagnostic issue??
if avalon engine replaces lexus 3.0 , why doesnt avalon have oil level sensor
I also have a '04 AUDI A4 3.0 Quatro and the low oil sensor comes on and goes away after I pull the oil stick out and put it back. I did notice that when I had the oil changed and it came on exactly 3,000 miles after that, which is the mileage recommended to change oil by the place I had oil changed. It goes away and comes back on after every 60/65 miles.
I am afraid to go back to the same garage because they might recommend something outrageous. How to find out which sensor it is and how to replace it by yourself. HELP!!
Posted on Oct 07, 2008
You have two sensors that could cause the light to go on. The oil pressure sensor and oil level sensor. Both are easily replaced by someone relatively OK with cars (DIY). You would want to spend the $100 or so and have the dealership do a full diognostic to verify if its truly the sensor and which one. In my case, same problem, and it has been verified that it was the oil level sensor.
Posted on Aug 30, 2008
I also have a 2004 Audi A4 3.0 Quatro and the low oil sensor comes on periodically. I pull the oil dip stick and put it back and it goes away. Maybe it will work itself out.
Posted on Aug 13, 2008
Tips for a great answer:
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this warning light or any other stays on in the dash it is indicating
that the systems control module (or the system sensor in the case of
lights like low oil pressure, door open indicators etc.) has detected
a fault, it then disables the system (this applies to ABS,TCS, TCM,
SRS and BCM faults and others) as long as the light is on. You must
now have the dealer hook up a special electronic diagnostic tool and
"scan" the system for the fault code that is stored for the
Legend of Abbreviations. ABS Antilock brake system.TCS Traction control system, TCM Transmission control module, SRS Supplemental restraint system, BCM Body control module
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bronchitis morning - Bronchitis ??? Information and Symptoms
Bronchitis ??? Information and Symptoms
is usually due to an infection and generally lasts for no more than a few weeks and will resolve either with treatment or on its own. It can be caused by the same viruses that cause the common cold and is a common complication of the cold or flu.
# Divya Madhukalp Vati Removes weakness & irritation, as well as increases the capacity of the brain by making it strong. # Divya Madhukalp Vati Cures the numbness of hands & feet and makes the nervous system strong.
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Divya Ashwagandha Churna for Stress, Fatigue and General Health # Ashwagandha (Indian ginseng) has many important benefits, but is best known for its commanding adaptogenic properties, meaning that it helps mind and body become accustomed better to stress.
' Powder of tulsi leaves added with saunth (dried ginger) and sugar when taken with hot water is a famous remedy for fever. ' A Tulsi seed processed in castor oil is very effective remedy for hair lice problem.
is almost always caused by viruses that attack the lining of the bronchial tree and cause infection. As your body fights back against these viruses, more swelling occurs and more mucus is made. It takes time for your body to kill the viruses and heal the damage to your bronchial tubes. In most cases, the same viruses that cause colds cause
acute bronchitis
. Research has shown that bacterial infection is a much less common cause of
than we used to think. Very rarely, an infection caused by a fungus can cause acute
Divya Singhnaad Guggulu for Rheumatism # Guggulu is the oleogum resin from a small tree (Commiphora Mukul) which grows in the Himalayas of northwestern India. It has anti-inflammatory and lipid-lowering properties. It also helps remove fat, excess fluids and ama from the body, and penetrates deep into the tissues.
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Divya Medha Kwath for Headache and Memory Enhancement * Divya Medha Kwath Cures chronic headache, migraine, sleeplessness or loss of sleep, negativity and depression.
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# Singhnaad Guggulu is used to address rheumatic conditions. According to Ayurveda, rheumatism is viewed as the body's inflammatory reaction to an excessive amount of toxins in the system. Singhnaad Guggulu combines the potent cleansing ingredients of castor oil and triphala, which remove toxins from the joints and blood. In addition, it contains anti-inflammatory agents, such as Guggulu, that work to calm and sooth painful and swollen joints. This formula serves to rejuvenate the body and improve digestion, thus minimizing further production of toxins and rheumatic symptoms.
Most worshipped plant in Hindu culture. It has a mythological background as tulsi is considered as lord Krishna's wife. Literal meaning of tulsi is incomparable so as the name suggest, it really has properties that are incomparable with any other herb. Every thing mentioned in Indian mythology has a scientific background. So as the culture of planting tulsi in center of court yard in Hindu homes. It is a strong belief that those who plant tulsi in there houses never get ill, as it is very lovable to lord Krishna and lord Krishna has blessed this herb with this property. Scientific reason of this story is that tulsi contains such a chemical composition that no mosquitoes and flies can come near the plant because of it s peculiar odor. Thereby by planting tulsi in courtyard prevents entry of these creatures in house thus rendering home safe from any diseases caused by these organisms.
# Divya Medohar Vati Also cures linked complications like insomnia, feeling of nervousness, palpitation, pain in the chest and head. There is no need to take any extra medicine for the relief of these complications. Intake of this 'Mukta Vati' will not produce excessive sleep in persons who by now have normal sleep.
affects babies and young children as their airways are very small and gets blocked easily. Bronchitis occurs until the baby is 2 years old. However, the peak occurrence affects infants mostly aging 3-6 months. Children who're mostly affected by this bronchitis are male's children, children who reside in crowded conditions, those who're exposed to cigarette smoke, and children who're not fed through breasts.
# It helps in relieving from complications like pains caused by it; # Helps in removing edema & pain of kidney; stops the tendency of stone formation.
# Divya Medohar Vati Especially useful in thyroid disorders (hypo & hyper thyroid), rheumatic arthritis, joint pains, pain in lumbar region and knee, joints.
Divya Sanjivani Vati for Cold, Fever and Flu * Divya Sanjivani Vati is the perfect medicine to combat cold, fever and flu. It helps strengthen the immune system so that there will be no recurrence of the sickness.
Signs And Symptoms ??? Fever is not common in people with acute
, although it may be a sign of another condition such as the flu or pneumonia. A
persistent cough
is the most common sign of
acute bronchitis
; this usually lasts between 10 and 20 days. In some people, coughing produces sputum (mucus); this does not mean that there is a bacterial infection or that antibiotics are needed.
* Divya Shilajeet Rasayan Vati Vayu-alleviating, promoter of strength and the quantity of semen (spermatopoetic). * Divya Shilajeet Rasayan Vati Particularly useful in night fall swapnadosha, prameha (obstinate urinary disorders including diabetes) and leucorrhoea.
* Divya Udarkalp Churna Stimulates digestion & digests ama (undigested material caused by impaired digestion & metabolism). Divya Vatari Churna for Arthritis
Tulsi finds great importance in respiratory tract disease. It gives marvelous results in upper respiratory tract infection (URTI). As mentioned earlier that it acts rigorously on kapha hence it works as good expectorant relieving from wet cough. It also finds its good use in
and asthmatic conditions. It helps to fight the cause of allergy by which our respiratory tract gets inflamed and then resolves the causative agent. Good results have also been seen in anti-tubercular treatment as it works as antibiotic eliminating the bacteria. It also shows good results in chest pains. Tulsi finds great use in fever as it act as antipyretic, pain reliever, and provides strength to our body.
unless you are a smoker antibiotic's are not needed bronchitis is not a bacterial infection it is viral. how ever you do need to go to the doc if you are having trouble breathing or if your cough is keeping you up they will give you a abutorol inhaler and some codeine cough syrup.
# It helps in total evacuation of stomach; removes disappointment & makes the body active. Divya Dant Manjan Tooth Powder # Helps in Strengthens the gums, as a result of which discharge of pus mixed with blood gets stopped;
Swami Ramdev Born in year 1974 also known as Baba Ramdev is in fact an Indian Hindu swami and an passionate admirer of Swami Vivekananda and Netaji Subhas Chandra Bose. He is mainly well-known for his efforts into popularizing Yoga Practices in different part of world. He is as well one of the founders of the Divya Yoga Mandir Trust that aims to popularize Yoga and offer Ayurvedic treatments.
Divya Pidantak Ras for Joint Pain and Arthritis * Useful in joint pain, arthritis, lumbar pain, cervical spondylitis, sciatica; gives immediate & permanent relief in all types of bodily pains.
* An excellent tonic for lungs to nourish them. Divya Triphala Churna for Rejuvination and Detoxification # Divya Triphala Churna detoxifies and rejuvenates your body. It gently cleanses & detoxifies the system while simultaneously replenishing & nourishing it, this formula supports the proper functions of the digestive, circulatory, respiratory & genitourinary systems.
Divya Kanti Lep for Increasing Skin Splendour * Divya Kanti Lep Instantaneously cures skin-disorders, viz. pimples, acne, wrinkles on face, loss of shining & luster, darkness, etc.
Colds in children are very mild and might last for about 7 to 10 days. It is known by a stuffy, bubbly, and runny nose accompanied by light coughing. Position your infant with her or his head elevated might aid her or his to breathe comfortably. Avoid contacts with your infants if you've colds. Simple, regular washing is very effective in preventing these colds. It's not advised to provide drugs to your kid without proper prescription.
* Divya Shilajeet Sat Very effective remedy for cold, cough, rhinitis, coryza, asthma (dyspnoea),
, weakness of lungs , tuberculosis, weakness of bones, general weakness, seminal diseases, diabetes, etc. Promotes immunity power, can be taken by all, i.e. men, women and even children, to cure diseases.
* Divya Kayakalp Tail Gives quick relief in cracks of hands & feet, burns, cuts & wounds. This oil is extremely useful & beneficial, so it should always be kept in each & every home.
Antibiotic treatments may help eradicate the symptoms and then cures the strep throat. It's necessary for seeking advice from 1 health care professional for obtaining treatment recommendation. This might prevent strep throats like scarlet or rheumatic fever.
Divya Madhukalp Vati for Diabetes # Divya Madhukalp Vati Activates the pancreas and helps it to secrete a balanced quantity of Insulin, through which extra Glucose gets converted into Glycogen.
Divya Kayakalp Tail Oil for Skin Problems, Cracks and Burns * Divya Kayakalp Tail Quickly curses all types of skin-disease, like ring-worm (dadru), itching, eczema, leucoderma, psoriasis, urticaria, freckles, skin allergy & sun-burning.
Bronchitis usually comes when some kind of infection happens in your upper breathing system. It shows abrupt symptoms and it's seldom considered like a separate entity in childhood. It's often accompanied with hacking, dry, persistent coughs which might last for 2 to 3 days and a mild fever. Coughing might worsen during night and sometimes it causes chest pains. The tachypnea rate during 1 minute is greater than 60 breaths.
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Divya Chandraprabha Vati for Urinary Disease # Chandraprabha Vati is Very famous & useful medicine for the diseases relating to urinary tract & uterus as well as seminal disorders.
Divya Madhu Nashini Vati for Diabeties # Divya Madhu Nashini Vati Activates the pancreas and helps it to secrete a balanced quantity of Insulin, through which extra Glucose gets converted into Glycogen.
Divya Pidantak Tail Massage Oil for Joint Pain and Arthritis * Divya Pidantak Tail Immediately relieves joint pain, pain of lumbar region and knee-joints, cervical spondylitis, slip disk, trauma & different types of pain, oedema & inflammation.
* Divya Kanti Lep Application of this paste absorbs all the complaints of the skin, as a result of which the skin again becomes healthy; the natural beauty of the face reappears; it also promotes splendor, shining & luster on the face.
Tulsi is being used in variety of herbal ayurvedic formulations. Most dominantly it is used in bronchitis and asthmatic conditions. It gives great relief in cough especially one predominated by kapha.
# Supports healthy digestion & absorption, gently maintains regularity. It is a natural anti-oxidant, and it assists natural internal cleansing. Triphala nourishes & rejuvenates the tissues.
* As Divya Kesh Tail is prepared with many celestial herbs, it also strengthens your eyes & brain, as well as cools the brain. * Divya Kesh Tail is also useful in headache & different types of head-diseases.
Divya Shilajeet Rasayan Vati for Impotency * Divya Shilajeet Rasayan Vati Produces positive effect on vatavahini nadi (nervous system), kidneys and channels which carry virya (semen).
# Divya Yauvanamrita Vati Exceedingly strength promoting & nourishing for persons whose body is exhausted & emaciated; and also useful for persons who are entering into old age.
Abhishek is an ex-
sufferer and he has got some great tips for
Treatment! Download his FREE 100 Pages Ebook, "How To Win Your War Against Bronchitis" from his website http://www.Health-Whiz.com/797/index.htm. Only limited Free Copies available.
Divya Amla Churna for Eyes, Digestion and General Health Amla or amalaki (Phyllanthus emblica) is full of medicinal actions and is considered as one of the richest possible natural source of vitamin 'C' or ascorbic acid. It also contains many necessary elements for keeping our body healthy and anti to germs and infections.
Divya Peya Herbal Tea # Divya Peya is An Ayurvedic drink, free from alcohol, having sweet taste & the best substitute for tea. # It Promotes immunity in the body, so protects the attack of kaphaja diseases
As we begin with the skin problems, as mentioned earlier it acts as anti bacterial and anti parasitic, therefore is widely used in infectious diseases. It act on nervous system providing them strength, relieves stress and also helps in relieving pain, as it is vata suppressant. It work as appetizer and promotes digestion by helping in secretion of digestive enzymes. It helps in preventing flatulence and avoids constipated stool. It also keeps check on any infection that might invade our digestive system. Tulsi is also seen very useful in heart disease. It provides strength to heart and helps in proper working. It also helps to detoxify any toxin that might be circulating through our body via blood thereby have the property to purify blood.
- The breathing pattern of your infants can be changed. Respiration would be considered normal if gas exchange (like oxygen) in the lung occurs. The measurement for breathing is taken each minute.
Divya Medohar Vati for Weight Loss # Divya Medohar Vati first removes disorders of the digestive system and then reduces the extra fat in thebody, making the body beautiful, compact, lustreful & active.
* Divya Medha Kwath Cures uneasiness. * Divya Medha Kwath Promotes memory. Divya Medha Vati for Memory Loss and Improving Intelligence # Divya Medha Vati Cures different types of mental disorders, like loss of memory, headache, insomnia, irritative temperament, epileptic fits.
Divya Mukta Vati for High Blood Pressure # Divya Medohar Vati Absolutely free from side effects. # Divya Medohar Vati Cures high blood pressure caused by any cause, either by kidney disorder, heart disease or by increased cholesterol, anxiety, tension, or for inherited reasons.
* Divya Gashar Churna helps in digesting the food, so there is no incidence of gas & acidity, etc., caused by indigestion. * Divya Gashar Churna immediately cures feeling of heaviness of abdomen, flatulence, colic pain and anorexia after food.
* Helps in treating fistula-in-ano if taken regularly. Divya Ashmarihar Ras for Kidney Stones # It is in powder form &, is diuretic; # It helps in dissolving deposited calculi & takes it out from the body
Mothers must understand the important truths about bronchitis. They may avoid hysterics and very late response if the children show bad health symptoms linked with bronchitis.
# If by somehow there is an attack of kaphaja disease, patient gets immediate relief by its use. # Stimulates power of digestion; strengthens body & brain, makes the brain tranquil; controls cholesterol & protects from heart-disease.
Divya Kayakalp Vati for Skin Disease, Acne and Pimples * Divya Kayakalp Vati Purifies blood, so cures all types of skin-diseases successfully. * Divya Kayakalp Vati Removes acne, pimples, dark spot on checks & spots on the face.
Divya Shilajeet Sat for Gout and Weak Immune System * Divya Shilajeet Sat Cures gout , cervical spondylitis, sciatica, pain in the lumbar region & knee joints, parkinson, joint pain & all other types of pain;
Divya Kesh Tail Hair Oil for Hair Loss, Dandruff and Headache * Divya Kesh Tail is like nectar for your hair; it cures untimely hair fall, dandruff, alopecia, premature graying of hair, etc. By applying this oil, hair becomes healthy & luxurious.
Yograj Guggulu is a traditional formula designed to reduce excess vata in the system. It is particularly useful for accumulated vata in the joints and muscles, which may be indicated by cracking or popping of the joints, tics, spasms or tremors. Chronic accumulation may lead to such serious conditions as rheumatism and arthritis. In vata-type arthritis, the joints may feel cold to the touch and although not necessarily swollen, they may be dry and painful, especially upon movement. Yogaraj Guggulu contains a synergistic blend of detoxifying herbs, including Triphala, Chitrak and Vidanga that work in conjunction with guggulu to remove excess vata from the joints as well as the nerves and muscles.
Divya Stri Rasayan Vati for Menstruation * Divya Stri Rasayan Vati Cures all types of diseases of woman viz., leucorrhoea, menorrhagia, irregularity in menstruation, pain in lower abdomen or lumbar region;
Mothers should observe the respiration rates of their children for 1 minute. Abdominal movements will be noticeable. Infants below 1 year old should have some 40-60 respirations in a minute. 1 year old babies should have 25-35 respirations in 1 minute. Toddlers should have 20-40 respiration a minute. However, crying increases respiratory rates as sleeping decreases the heart rate.
Infant Bronchitis is basically a viral infection. Sometimes symptoms are so apparent in children having bacterial pneumonia. This causes serious or very fatal consequences if it's not treated at the right time.
* Intake of this medicine makes the cells of the lungs more active, and removes the inflammation of bronchioles & bronchi. So lungs become capable to take more oxygen & patient gets rid of chronic diseases like
Divya Arshakalp Vati for Piles * It helps in curing all types of piles like bleeding piles as well as dry piles * Helps in relieving complications like pain, burning sensation, itching and colic pain.
# Takes away food-particles from teeth; # Helps in removing foul smell of the mouth, # Makes salivary gland fit for doing its work properly. Divya Gashar Churna for Removal of Gas
# Promotes strength, sustenance & luster, produces gradual & enduring effect in prameha (obstinate urinary disorders including diabetes) & complications arising out of it; cures seminal disorders caused by gonorrhea and syphilis.
* Divya Vatari Churna It is anodyne and it cures ama-vata (rheumatoid arthritis), sciatica, pain in back as well as in lumbar region. Divya Yauvanamrita Vati for Weak Bodies and Impotency
To define
, it's just a small cold which will spread out throughout these bronchial tubes of the lungs. Bronchitis possesses its degree of severity. It might range from a small condition without fever then it becomes very much serious. Normally, a cough is present. This might be extremely dangerous for infants. They might feel shortness in breath. Squeaky noise would be heard if the infant starts breathing. If you see these in your kid, then you should call a physician.
- Sore and strep throats might also affect these kids. This condition is governed by inflammation of tonsils which gives pain inside the throat and accompanied by fever, sometimes. Swallowing might be very difficult. A very itchy throat might often be associated with cold. Toddlers possessing strep throat might be irritable, possessing low fever, losses in their appetite, having swollen glands, and having yellow spots over their tonsils.
Biological name of tulsi is Ocimum sanctum and in common English language it is called holy basil. This herb is commonly found everywhere in India. Plant height varies from 2 - 4 ft. It flowers in winter season i.e. about December to February. It contains some biological active chemical compounds like ursolic acid, luteolin and apigenin extracted from leaves. Herb has katu and tickt rasa predominance. It is ushan (hot) virya in potency. It has laghu (light) and ruksh (dry) properties. Its major act is of as krimighan (anti bacterial and anti parasitic). Plant parts used are leaves, flower, seeds and root.
Dr John Anne
Learn More about Natural Bronchitis Remedy
Is Bronchitis Contagious?
Yes and no. It is not a trick question or answer. The real answer is - it depends. Bronchitis is divided into two very different categories. First is acute bronchitis which is what most think of when they hear the word bronchitis. This type of bronchitis is caused by a viral infection called influenza and is highly contagious. It is easily spread by coughing, sneezing, and even simply breathing....
Complementary and Alternative Treatments for Emphysema
Nutrition and Supplementation Before breakfast, drink a mixture of one teaspoonful of pure, cold-pressed olive oil and apple juice to provide essential fatty acids and help eliminate toxic waste. Experts recommend a raw-foods diet with emphasis on vegetables and raw fresh vegetable juices. Garlic and onions should be part of the daily diet. Frequent use of spicy foods, such as chili...
Infant Bronchitis - Seeking The Best Solutions To Treat Your Kid
To define bronchitis, it s just a small cold which will spread out throughout these bronchial tubes of the lungs. Bronchitis possesses its degree of severity. It might range from a small condition without fever then it becomes very much serious. Normally, a cough is present. This might be extremely dangerous for infants. They might feel shortness in breath. Squeaky noise would be heard if the...
Natural Cure in Bronchitis
Bronchitis is a disease of the lungs. It is an inflammatory disease. The pathogenic agents which determine Bronchitis are viruses, bacteria or fungi. Bronchitis is also influenced and worsen by the weather. So it is recommended to avoid wet weather and winds. A natural cure includes different oils, a well balanced diet which means fruits, vegetables and honey. One of the most...
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|Shanghai Stadium
|Tongji University
|Shanghai University of Finance and Economics
|Hongkou Football Stadium
|Changning District
|Huangpu District
|Shanghai Botanical Garden
|Hongkou District
|Fudan University
|Zhabei District
|Shanghai Art Museum
|Jade Buddha Temple
|Chang Feng Park
|Nanjing Road
|Yu Garden
|The Government of Shanghai Municipality
|Shanghai Railway Station
|Oriental Pearl Tower
|Super Brand Mall
|Changshu Road (Shanghai Metro)
|Xujiahui (Shanghai Metro)
|Shanghai South Railway Station
|South Shaanxi Road (Shanghai Metro)
|Laoximen (Shanghai Metro)
|Zhen Ping Road
|Caoyang Road
|Jiangsu Road (Shanghai Metro)
|Xinzha Road (Shanghai Metro)
|Jin Mao Tower
|The Bund
|Bund Center
|Lupu Bridge
|Central He Nan Road Station
|Nan Pu Bridge
|Peoples Square
|South Huangpi Road
|Jingan Temple
|Shanghai Museum
|Zhongtan Road
|Jingan Temple (Shanghai Metro)
|Peoples Square (Shanghai Metro)
380 South Huang Pi Road
0 reviews Guests consider this Hotel as correct.
380 South Huang Pi Road
Shanghai, China.
Among others, the 88 Xintiandi Hotel Shanghai offers the following services: Room Service, Disabled Access and Air Conditioned.
The 88 Xintiandi Hotel Shanghai is a 5 star Hotel. The rooms quality and cleaning service are correct, this Hotel is close to Super Brand Mall, Jingan Temple, Lupu Bridge, and other sights to see.
In addition to they have dry cleaning service, as well as this hotel is the perfect choice for people who want to book non-smoking rooms. Not only tennis courts are one of the most popular services of the hotel, also enjoy this hotels restaurant.


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The City of Elizabethtown invites you to attend a Public Visioning Workshop for the Envision Elizabethtown 2040 Comprehensive Plan. Elizabethtown, KY – The City will be hosting a public visioning workshop on July 18th from 4:00 -6:00 pm at the Pritchard Community Center (404 S. Mulberry St.) that will serve as the first opportunity to … Continue reading HELP ELIZABETHTOWN ENVISION & PLAN FOR THE FUTURE AT UPCOMING PUBLIC WORKSHOP PRESS RELEASE AND NEWS ARTICLE
Author: swisertswdg
The City of Elizabethtown kicked off the planning process for the Envision Elizabethtown 2040 Comprehensive Plan in May of 2019. Residents, business owners, and community organizations are invited to be an active part of this process. To find out how you can get involved, visit the Timeline page and subscribe to receive email updates.


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Map of Gaston Mississippi MS
Gaston Mississippi MS Map professionally designed by GreatCitees.com. Feel free to remix and share.
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Madelyn Marie
Jessica Lynn and Madelyn Marie are two hot pieces of a love triangle. Madelyn's ex, Johnny, is dating Jessica but Jessica is secretly fooling around with Madelyn. When Jessica calls both of them to her place, things turn from strange to sexy once all the pieces fall into place... (Video duration: 33 min)
I guess, ideally, I would be making love to my girlfriend tonight in my huge house. However, I don't have a girlfriend, mostly because I'm never home. So maybe this isn't ideal, but my girlfriend tonight is Madelyn Marie. She's sexy, sweet, gentle... kind of like my girlfriend would be... if I were ever home. At least this way my girlfriend is always in lingerie, can't wait to please me, and never needs anything outside the bedroom. I'm sorry, I think I just said this wasn't ideal. I don't really know what I was thinking when I said that.
Madelyn Marie, the head of human resources, is giving Justin a talking-to because women around the office have complained that he's been touching them inappropriately. To give him a taste of his own medicine, Madelyn has Justin strip down, and she spanks him on the ass. She tells him that she can help him with his problem, and puts her hand promptly on his cock. She follows company protocol and sits on his dick until he cums all over her.
Madelyn Marie and Joe have been madly in love for years. They enjoy each other's company, like the same things, and have an amazing sex life. After months of trying to bring it up with her husband, Madelyn finally tells him what her greatest fantasy is. Although Joe is a little hesitant, he'll do anything for his wife, even let another dude fuck her.
Download Hardcore Wife Videos at Real Wife Stories now!
Madelyn Marie heard about our party and was bored so she decided to come and check it out. Well boy did we have a surprise for her... Ramon was ready and waiting. Now Madelyn was pretty horny herself. As soon as she got on the couch, she began playing with herself, warming that nice pussy up for Ramon. As soon as Ramon came in, that's where all the real action began!
Click here to watch this whole 100% uncensored XXX Video!
Porn-Star.com Unveils New 'Porn Stars Top 100'Carrying on with its yearly tradition, famous free pornstars website porn-star.com has compiled the Top 100 Most Popular Pornstars of 2011, an actual ranking of the 100 most visited pornstars on the site in the past 12 months. Congratulations to Madelyn Marie who is ranked number 42!
Check out the full list here: Top 100 Most Popular Pornstars of 2011
It's Madelyn Marie's big day! The Royal Princess of Porn is getting married to Ramon, the Royal Prince of Porn. Their union leads to a hot and hardcore session of matrimonial humping, the likes of which you've never seen!
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Madelyn Marie is mesmerizing with her chocolate brown eyes staring back at you. Wearing red satin lingerie, she touches the length of her curvaceous body before stripping down. Feeling as horny as ever, she squeezes her luscious tits together and spreas wide open to finger her tight pussy.
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Madelyn Marie Lesbian Action From Brazzers Network
Scene description: When Madelyn hits a rough patch with her boyfriend, she decides to move into a women's shelter. Something seems weird though. Everybody living there seems to be a little bit too comfortable around Madelyn. When the head of the house, Capri, finds out that her newest tenant is talking to her ex, she's not too happy. She'll teach her a lesson she won't soon forget.
Check out the full lenght video in hd at Brazzers Network!
Madelyn Marie Gets Fucked In This Gallery From Digital Playground
Gorgeous latin pornstar Madelyn Marie in a hot sex scene. She drops her sexy outfir and gets down to business. Sucking and fucking like a pro.
Check out the gallery here or go to Digital Playground for the full set and video.


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Confitex USA Launch
For the 25 million Americans who experience bladder control issues, few underwear products have combined comfort, fashion and performance – until now. Confitex has introduced the first line of fashionable leak-proof and washable underwear designed for both men and women with light bladder leakage (LBL).
Confitex's collection of light and moderate absorbency underwear and lingerie is now available in the U.S. after initial success in the UK, New Zealand and Australia. Combining patented textile technology and high quality fabrics with discrete, confidence-boosting designs, Confitex products for people with LBL look, feel and perform like regular underwear and lingerie.
"People who experience light bladder leakage should be able to enjoy their lifestyle, freedom and independence no matter what happens," said Confitex CEO and Co-Founder Dr. Mark Davey. "We created Confitex to enable people who suffer from LBL to live the life they want to live."
Each pair of Confitex underwear features an advanced inner layer that wicks moisture away from the skin quickly, a high absorbency middle layer that provides maximum moisture retention, and a leak-proof outer layer that protects all day long. This results in breathable, odor-free, pad-free and machine washable absorbent underwear that is suitable for any age or style.
According to a Confitex survey of 1,008 U.S. adults, 25 percent of women and eight percent of men say they have experienced LBL. The condition is particularly common for women after childbirth and during menopause and for men dealing with prostate health issues.
Yet, it remains an uncomfortable subject for those who suffer from it. The Confitex survey also found that 22 percent of Americans who have experienced LBL are embarrassed to discuss it with immediate family members. But if presented with a washable, leak-proof and fashionable underwear alternative to disposable products, 90 percent of those who've experienced LBL say their confidence and freedom would be restored.
"I see many patients who are seeking help in managing their LBL," says Urologist and Sexual Health Expert Dr. Jennifer Berman. "LBL is more common than most people think, and it can be an embarrassing and limiting condition."
Dr. Berman is partnering with Confitex to help introduce the product line in the U.S.
"Unfortunately, few options exist on the market for LBL protection and they consist of products that can make people feel self-conscious due to bulkiness and potential for odor. What differentiates Confitex is its revolutionary textile technology and fashion-forward design, which wicks fluid, prevents odor and helps restore confidence to people who experience LBL."
Confitex washable and leak-proof underwear is available in a variety of colors, sizes and absorbency levels in both women's styles (hipster, boy leg and full brief) and men's styles (full brief and short brief) for $34.90 on www.ConfitexUnderwear.com. The women's collection is also available on www.HSN.com.
Survey Methodology
The Confitex Light Bladder Leakage Survey was conducted from May 4 to May 7, 2017, using ORC International's Telephone CARAVAN® omnibus among a landline and cell phone probability sample of 1,008 U.S. adults age 18 and older. The margin of error for each sample was plus or minus 3.09 percent at the 95 percent confidence level.
Confitex makes comfortable, fashionable and premium performance underwear that is designed for men and women with light bladder leakage (LBL). The Confitex collection of leak proof undergarments is thoughtfully and discretely designed to look and feel like real underwear and lingerie. Using a patented textile technology that was originally created to help keep extreme athletes dry, Confitex products are machine washable, dryer-friendly and long lasting. Free of pads and plastic, washable Confitex products offer consumers with LBL an eco-friendly and confidence-boosting alternative to disposable products.


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Well, Christmas is nearly here at Templeton's Hardware and PC Tucknott, Doreen and myself would like to wish you a very Merry Christmas !
The new news here is that recent circumstances (which I am not prepared to go into) have resulted in me deciding to share some of the key business decisions with PC Tucknott and Doreen. Tucknott has now finished his community service order following the scout in a headlock incident and Doreen is happier now that Tucknott and I have started lifting the toilet seat and doing No 2's at home rather than at work.
Templeton's is a happy workplace.
So, I've formed a Buying Committee and Tucknott, Doreen and I meet on Wednesday mornings to mull over the latest market offerings. I am proud to announce that we have decided on our key range offering for the season 2012/2013. All the products below are available in store now at a range of competitive prices. Do pop buy and stock up on
The Motorized Rolling Pin
No longer will you have aching wrists or "rolling-pin elbows" with our fantastic motorized rolling-pin. Just press the button on the handle and go with the flow. Price £36.99
The Family Blankeez
God we know its cold at the moment – especially in East Yorkshire, but now families can wrap up toasty warm with the Family Blankeez. The brilliance of this clever invention is that it doubles as a cover for the family on weekend bike rides in less than clement weather. Price £27.99
The Pet Sweep
How many times have pet owners had to clear up muddy paw marks from the previously beautifully clean kitchen and hall floors. Wel know we let the pets do the work with Pet Sweep. Simply attach the dust boots to the paws of your favourite pooch and sit back and watch your floors get clear. Price £19.99
Merry Christmas
Derek, PC Tucknott and Doreen – Templeton's Hardware Buying Committee
Filed under: Extra income, shoes | Tagged: christmas, christmas gifts, christmas presents, father christmas, free gifts, gifts | Leave a comment »


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Love your Cohoma Coffee and want to gift some to your friends and family? We've got you covered.
Our gift hampers offer you the convenience of selecting the products that you want and making your gift, exactly your way!Fill out the form below and we'll help you create the perfect gift


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Such was a house I was called to to look at storm damage to the stair window. As I finally negotiated my way down a lane and missing the entry causing me to go on to a railway station that I did not know existed, I finally went across the cattle grid to be presented with this.
Yes, as I was to learn, this is a Greek Thomson house, possibly his first outside Glasgow. This is an architect of such importance that there is a society established to study his works. This grand house is impressive in its size as well as in the amount of light he allowed into the building. No other architect at the time was filling the wall with so many windows.
The front door is as impressive as the rest of the house. And probably the scale was meant to impress visitors with the wealth of the owner. The front doors are twice the height of the average person.
The back of the house is no less impressive than the front. The house is marred by the modern extension at the left, but still is a handsome house. Note the number of windows all of which face over the River Clyde to the south.
This gives an impression of part of the view just from the garden.
The view from the first floor must allow views over to the Mull of Kintyre and the Isle of Aran.
But now I have to get to work. This is the external view of the area of storm damage.
Fortunately the leaded glass had been covered with protective glazing some years ago. This meant that the falling slates and guttering extensively damaged the external glazing, but not much of the leaded glass.
As I was welcomed into the house, I noted the generous cloak rooms with the fine cornices at the upper level of the walls.
This kind of elegant decoration continues into the modern down stairs lounge - which would have been the dining room originally.
As we went round the stairs to the kitchen, there were a pair of windows under the stair:
And just to the left of them the door into the kitchen:
You can see from these pictures that coloured glass was not an important element in Thomson's architectural decoration. What there is is simple and elegant, relying on varied textures in the glass for interest.
Now, really, I must get to work. The falling roofing materials had broken the protective glazing extensively, and in some places had come through to the leaded glass.
My job was to get up to these breaks, which were about 4 metres above the landing, and repair them. Fortunately, the client has a friend who runs a scaffolding firm. The scaffolding was put in place for me to get up to the glass. It was difficult as much of the broken glass was pieces next to each other and the lead had been twisted by the impact. The obvious pieces are at the right centre of the picture, but there were others broken under the glazing bars.
Fortunately the broken original glass has modern imitators that are a very good match, so I was able to fit the glass and leave it appearing to be original.
I have been to this town many times, but would never have seen the outside of the house, let alone its inside. The owner of the house is proud of it and happily pointed out lots of things to me, but of course does not want a string of visitors. So, my job is a good job for someone - like me - who is interested in domestic architecture


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Purdue UniversityNews Service1132 Engineering Administration BuildingWest Lafayette, IN 47907-1132Voice: 765-494-2096FAX: 765-494-0401
August 23, 2001
'Imprinted' Gels Hold Promise For Future Medical Devices
Sources: Nicholas Peppas, (765) 494-7944, email@example.com
Mark Byrne, (765) 494-3331, email@example.com
WEST LAFAYETTE, Ind. -- Scientists at Purdue University are creating a biological sensor for glucose in research that ultimately may help to design "intelligent drug delivery" devices that could be implanted in the body to administer medications such as insulin.
The researchers formed a mesh-like "biomimetic" gel containing glucose molecules and then used a slightly acidic chemical to remove the glucose, leaving behind spaces where the glucose used to be. If placed in a liquid such as blood, glucose in the liquid diffuses into the gel and binds to the empty spaces. The gel is said to be "imprinted" for glucose molecules. Similar materials might be used in future medical devices to sense the presence of glucose, perhaps signaling an action to release insulin or other medications for diabetics, said chemical engineering doctoral student Mark Byrne.
"I'd be the first one to say that we have a lot of work to do, but our findings so far are very encouraging," said Byrne, who will discuss the work Tuesday (8/28) during the American Chemical Society's national meeting, Sunday through Thursday (8/26-30), in Chicago. The student is working with Nicholas A. Peppas, Purdue's Showalter Distinguished Professor of Chemical and Biomedical Engineering, and Kinam Park, a professor of pharmaceutics and biomedical engineering.
"There is a lot of interest in glucose sensing for diabetes research," Byrne said. "And that has been the main focus of this work. However, we are also working on systems that bind other molecules that are important for the treatment of other conditions.
"It's a tremendous task to design something that will eventually work in the human body."
The approach attempts to mimic how some molecules attach to "binding sites" on other molecules, similar to the way in which a key fits into a lock. Such binding is critical to various biological processes. Each binding site, however, must possess the proper shape and other characteristics for it to bind to a specific molecule.
The biomimetic gel contains numerous binding sites for glucose.
"Essentially, we are trying to design what nature has done so well, and that's a difficult thing to do," Byrne said. "We are creating artificial binding sites."
Artificial sensing mechanisms might one day be incorporated into medical devices implanted inside the body. The sensing mechanism would be part of a meshwork containing medications inside numerous microscopic cavities. Sensing glucose in the blood would automatically trigger the meshwork to expand, opening pores and releasing insulin or a medication that would enable the body to more efficiently absorb insulin.
"Ultimately, it would be nice to design something of this sort that would provide therapy for type one diabetes," Byrne said. "It would automatically sense when the glucose level was high, and then it would release an appropriate level of insulin. Then, whenever the glucose level went down again, the polymer gel would intelligently stop the release of insulin."
About 700,000 Americans suffer from insulin-dependent diabetes, also known as type one diabetes. People who have insulin-dependent diabetes must take insulin, either by injecting themselves with a needle at least twice a day or by using a battery-operated "insulin pump." The pump is worn outside the body, on a belt or in a pocket, and delivers a steady supply of insulin through a tube that connects to a needle placed under the skin.
Because insulin-dependent diabetes usually afflicts young people, it used to be called juvenile diabetes. About 12,000 children in the United States are diagnosed with the disorder every year.
The gels might be incorporated into a drug-dispensing system that receives signals from the sensors and then commands the meshwork to expand, releasing insulin. Another possibility is that the sensors themselves might directly command the meshwork to expand.
"The system would be sensitive to what is in the blood, and then, depending on what it sensed in the blood, would administer the right amount of drug," Byrne said.
Such applications probably will be at least five years in the future, researchers said.
An important aspect of the Purdue research is that the scientists have been able to make the gel with a non-toxic solvent and in water, meaning it would be compatible with the human body.
The gel is created by ultraviolet light, which causes molecules surrounding the glucose to form the binding sites. Then, the glucose is removed with an acidic chemical, leaving the empty, synthetic binding sites.
The research is supported by the National Institutes of Health, and the work is being conducted under the auspices of the recently formed Program in Therapeutic and Diagnostic Devices, which is supported by the National Science Foundation and directed by Peppas. The program brings together engineers from a broad range of backgrounds and expertise and was formed to train researchers in the field of biomedical devices, including artificial organs, biomaterials, controlled release devices and tissue-engineered materials.
Writer: Emil Venere, (765) 494-4709, email@example.com
Related Web sites:
Nicholas Peppas: http://ChE.www.ecn.purdue.edu/ChE/Fac_Staff/Fac.Staff/peppas/
American Chemical Society: http://www.acs.org/
Biomimetic Materials for Drug Targeting and Drug Delivery
M.E. Byrne and N.A. Peppas
Engineering the molecular design of biomaterials by controlling recognition and specificity is the first step in coordinating and duplicating complex biological and physiological processes. Design and synthesis of artificial molecular structures capable of specific molecular recognition of biological molecules is classified and fundamentally defined by the term biomimetic materials. Molecular imprinting and microimprinting techniques, which create stereo-specific, three-dimensional binding cavities based on a biological compound of interest, will produce these biomimetic materials for intelligent drug delivery, drug targeting and tissue engineering devices. Developments of particular interest to the field are expected to be wide and far-reaching, such as recognition of undesirable biologicals, nano-scale patterning and recognition of proteins, site-specific interaction with tissues, etc.
We have been successful in synthesizing novel glucose-binding molecules based on non-covalent directed interactions formed via molecular imprinting techniques within aqueous media. Numerous polymer systems were identified; however, the synthesis scheme and biological oriented application limited the choices to a few systems. Of particular importance in our polymer design is the network morphology, which spatially varies in crosslinking density (microporous and macroporous regions). Emphasis has also been placed on fundamental studies regarding the specific recognition event needed to produce a spatially defined recognition site. By tailoring the polymer gel structure composition, effective recognition sites can be created in polymer gels.


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Just as children are precious in Jesus's sight, they are precious in ours too. The safety and security of your child are among our top priorities. We have created a safe, nurturing space for your child to learn about God and grow with others. We look forward to meeting you soon!
Each week when checking a child in at the KidZone desk you and your child will be given a matching security sticker by one of our team members. Parents are asked to present the sticker at pickup where one of our team members will match to your child and then release them to your care. Thank you for helping us keep the safety of all our children a priority here at Exchange Church.
The Parent Cue App helps every parent do something each week to help move their child toward a deeper faith and a better future. Parent Cue allows parents & kids to continue the conversation through the week that our KidZone Team will begin each Sunday.