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Pi Shop
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The pizzas were delicious but we all wished that there was slightly more variety and two of our party asked for sauces to dip their crusts in but there was only one such dip available. It was a delicious dip though!
It was okay a decent pizza friendly service. We had a table indoors a bit disappointing on a warm sunny evening no ones fault. Lovely setting though and good ice cream
Very simple menu of pizzas, deliciously prepared in a wood burning oven. Delicious!
Excellent pizza and salad. Very pleasant cool surroundings on a hot day. The service was excellent: there when needed and quietly in the background at other times
2nd time I've been to Pi shop, and at least the 5th time my partner has been. Every time is just as Good as the last (if not better), and I couldn't recommend it enough! Perfection 👌
We'd heard good things about Pi so we were keen to try it. The location is very nice, overlooking Bathurst Basin. It was pretty empty when we arrived, but the bustling bar next door made it feel continental and lively.
The service was professional, but also kinda indifferent.
The food was pretty good. We're spoiled for choice for decent pizza joints in Bristol, and this was definitely at the higher end, with a nice doughy base, and decent tomato sauce and cheese.
Where it fell apart for us was the bill at the end - £60! The pizza was good, but not good enough to be 50% more expensive than other restaurants. The stinger was that my son had the kids meal, with a drink, pizza and ice cream, for £5, and I couldn't see any difference between his pizza and mine, other than the toppings. This made it feel like I basically spent £13 on a bit of deli meat.
We really wanted to like this place, and while the food was good the price left a bitter taste. We'll be going elsewhere in future because we want to be able to afford our mortgage repayments.
We went for my sons 7th birthday. A very nice evening with great food and service. The children's menu is excellent value and was thoroughly enjoyed by all three of our children. We were early so enjoyed a table outside. The service was quick and attentive which with three hungry children was great.
Very disappointed unfortunately. We were booked in advance for a special retirement party for a colleague who had worked at the Bristol General Hospital for 30+ years. We made a request if the evening was nice we would like to sit outside. We were greeted with "its first come first served for outside seating". An email to this effect would have been appreciated, and not even a 'so sorry!' Instead we were tucked in a corner. We found the pizza's to be standard.
Lovely location but the food was bland and overpriced
This was the fifth time I went to the Pi shop and it was brilliant like all the other 4 times :) The service is always excellent and the food is gorgeous. By far the best pizza in Bristol. Nice cocktails too :)
We really enjoyed it the first time we went here and thought it was great. However think the prices have gone up and didn't think the pizza was as nice as it was the first time (and compared to other Bristol Pizza places). There's a good drinks menu and a great venue but if you're picking a restaurant solely for the pizza I think there's better options.
Average tasting overpriced food in a nice environment. Pizza is better elsewhere in the city, at almost half the price.
Four of us dined at the PI Restaurant, which is basically a pizza restaurant with various accompaniments. Beautifully converted premises, attentive staff, fabulous location. The pizzas were okay, just not value for money. The wine was also too expensive for what it was. We are older ladies who are relatively easy to please, not picky or fussy, however we did feel a little short changed.
Always tasty but, sadly, no longer value for money. The prices have gone up considerably- £50 for 2 pizzas and 2 drinks is unreasonable. We won't be rushing back, especially with so many other pizza options nearby.
Love it here. If you can get a seat outside on a sunny day there's nothing better than enjoying delicious pizza and a bottle of wine in the sunshine. I came here for a date night with my boyfriend and we decided to try out the pizza tasting menu. Shared starters, then 3 mini pizza of your choice to share, topped off with a little pudding. Was wonderful to sample small bits of all the yummy flavours and having some time in between each pizza and course was lovely - changed our evening from an hour or so to several hours enjoying each others company and the warm weather. It's not cheap, but the quality, service and ambience make this a great place to go with friends, colleagues or on a date.
Love the Pi Shop. Excellent charcuterie, cheese and pizza. The ice-cream & drinks deserve mention too. Thanks for looking after us so well - loved the new tasting menu idea too. FEAST!
Pi shop takes pizza eating to a whole new level. Great ingredients makes great food. The only down side is the walk home!
Not our 1st visit, and as good as ever, We had the new dough base and it was just as good just slightly lighter. I note they are about to introduce more starters and revisit the pizza offering. Got to go back.
We were place next to fire extinguishers. PI needs to rethink such an area for its customers. Other than the seating place, PI is outstanding!
There are so many good pizza restaurants nowadays, but this one stands out above any I have ever tried
Amazing pizza, really friendly staff and a great restaurant.
Great meal at Pi Shop. Their lunch and afternoon menu is great value at £12.
Excellent food, attentive service nice atmosphere.
Overall, a disappointing experience.
Having had a lovely time at Casamia last year we really wanted to like the Pi Shop.
The pizza was soggy and impossible to keep on your fork. When we mentioned this to the staff we were told that they had a new mozerella supplier just that day and they knew that was causing it and they were still trying to get it right. It begs the question that if they knew this how come they were still prepared to offer a sub standard product to customers? They didn't charge us for our £3 salad, the least expensive item on our bill.
The young staff were somewhere on the scale between over confident and arrogant,
sincerity is not yet part of their vocabulary.
Maybe our expectations were raised to an unreasonable level at Casamia.
I'm happy to give them another chance to see if they have remedied the sogginess another day but my wife may take some persuading.
It was very lovely, serving only pizzas. Location was very good.
This was my first time visiting pi shop and I thought it was lovely, good quality food, beautiful setting and the staff were really friendly and helpful. Will defiantly return!
Slightly pricier than the competition but definitely worth the extra £ or two. Nice surroundings and a great pizza oven.
Two very good pizzas and some soft scoop ice cream (showing Pizza Hut how it should be done) to follow. Well-trained staff and a pleasant environment to soak up all the beer we'd been slowly sinking throughout the afternoon.
While Franco Manca is a great baseline for a city to have when it comes to pizza, this was a cut above. I look forward to returning.
Delicious pizza, ice cream and great service. Would definitely go back.
We came here for my mother's birthday and there was no acknowledgement of this by our waiter. After our food arrived very quickly we asked for another bottle of wine and was told by our waiter "you won't have time to finish another bottle of wine before the next table arrives but you can sit at the bar". No apology or even a warning when we first sat down or made the booking that we only had just over an hour to eat and drink. The atmosphere was nice, cocktails and pizza, though an extremely limited menu and ice cream as the only option for dessert. The overall attitude and the rush to get us out was really disappointing. Especially after paying £28 a bottle of wine £16 a pizza you would expect a higher level of customer service.
Cracking Thursday night cocktail and the best pizza outside of Naples. The team are top notch and prices depend on how much you want to indulge. The ice cream this time had moved onto Black Forest, excellent.
Tasty pizzas with a lovely short menu, which I really appreciate. Delicious artichoke starter which I would definitely have again. Really pleasant staff who were attentive and not overly so. Enjoyed the experience a lot and will return and recommend.
We enjoyed our Pizzas very much, they were piping hot and really tasty.
The waitress was very friendly and the surroundings were characterful.
I'd definitely eat there again.
We were really excited to try this place, but honestly, the starter was a warning sign. The garlic bread was almost tasteless; the garlic lacking a punch and there appeared to be a lack of salt in the dough. The pizzas when they arrived were just sloppy and the tomato sauce used was disappointingly bland.
The sole good bit was the G&T using a favourite local gin, but even that wasn't served as specified on the menu. Given the relationship of this place to Casamia (which had a good reputation, but now we are unlikely to visit), we were very disappointed... especially for a cost of £48.
We didn't like the atmosphere either, really. We felt it to be quite sterile and bland, but that's more a personal preference.
Short menu but everything excellently executed. Super pizzas and salads. Good selection of local beers. Friendly and prompt service.
Pizza was overloaded with olive oil,
My partner wanted to show the Waiter how the pizza had olive oil dripping on to the plate and his response was that's the pizza you ordered / the way they are served in Napoli.
Really disappointed with the service and attitude against "Italian" pizza
Will not be returning
Good night as expected
Lack of choice especially around desserts
Great Pizza, good selection and all beautifully prepared. Good dough, thin base but good sour dough crust. Opted for a starter but it was a bit too big. Leftovers boxed for us which was helpful and offered without asking. Pleasant staff. Lovely area, lots of development looks as if it will become a vibrant area. Would be great to visit on a warm day as outside eating overlooking water would be lovely.
Really good pizza - interesting combinations
I had aubergine with ewe cheese - really good
quick efficient service
Pi Shop does offer delivery in partnership with Deliveroo.
Pi Shop is rated 4.5 stars by 76 OpenTable diners.


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Ida Lundén
(born in Gothenburg, 1971, resident Stockholm/Sweden), is a contemporary composer mainly in the EAM and chamber field but she has also written music for theatre, film, dance and orchestra. She was the composer in residence at Swedish Radio P2 in 2011-2013. In her music you can hear her exploring of sounds and new ways of playing, for example, in her piece Vingring and Rrrp! In Boom-choff-leuit you can hear African wind-music and in Spänst åt alla (Vigour to everyone), the music is a performance-based solo piece. In Var modig mitt blödande hjärta (Be brave my bleeding heart) she worked together with her sister, the singer and performance artist Sara Lundén. In another project, which resulted in the music for the film Transire, she wrote music for the duo Jonny Axelsson and Ivo Nilsson, for self constructed synthesizers, trombone, percussion and five co-players. Lundén studied jazz piano and improvisation at the College of Music and Drama in Gothenburg. In 1996-1998 she studied composition with Sven-David Sandström at Gotland School of Music and in 1998-2002 with Pär Lindgren and Bent Sörensen at the Royal College of Music in Stockholm, in 2001-2002 with Mathias Spahlinger, at the University of Music in Freiburg, Germany. In 2002-2005 she studied and graduated with a Postgraduate Diploma in Music Composition, from the Royal college of Music, Stockholm. Between 2004 -2005 she held a scholarship at KunstForumHellerau, Dresdner Zentrum für zeitgenössische Musik and 2006 she was artist in residence and received the Omega Award at Visby International Center for Composers. Lundén is a keyboard player and performer in the fields of improvised music, avant pop and other experimental music. She collaborates with artists, film makers and dancers and plays regularly in the groups Ludd, together with Lise-Lotte Norelius, Syntjuntan and Konatus with Dror Feiler a. o. Lundén is a member of the board of the Swedish Arts Grants Committee.
Selected works: Grenvarv a musical walk in Pildammsparken, Malmö. A co-operation between landscape architects, visual artists, composers and musicians; Traktorbiblioteket for fiati quintet, perc; Concerto for playground together with Åse Ekström, daycare children play following a score. In Almedalen, Visby; Ett sorts omelett, an amplified making of an omelet mixed with tape, overhead projection and egg slicer. Lilla p for fl, vl, vlc, pf, composed for The Peärls Before Swine Experience; Klogolk for 3 rec, cemb; Ibland är man glad, fast lite ledsen, sound installation; Schfstr for 2 cb; Dadodado, 2003,for chit solo; Hlp for fl solo and electronics, com. by Anna Svensdotter.
Publications direction: Available at Svensk Musik/Swedmic AB
Awards, selection: 2010, Stockholm Stads Kulturstipendium (The city of Stockholm culture grant); 2006, 2007, Artist in Residence at VICC, Visby; 2007, FST, (The society of Swedish Composers); 1999 Fredrika-Bremer-Förbundet (The Fredrika Bremer Alliance); 1994 Adlerbertska stipendiefonden (The Adlerbertska grant foundation)
Ivana Loudovà
(born in 1941 in Chlumec, in Czech Republic, resident in Prague), composer. She studied composition at the Prague Conservatory and Academy of Arts, as well the Paris Conservatory. Her teachers were M.Kabelàč, E. Hlobil, O.Messian and A. Jolivet. She has written more than a hundred works: for orchestra, chamber music, vocal music, choral music, pedagogical music. Her works are published by C.F Peters, G. Schirmer (USA), Computer Music (NL), Panton and Supraphon (CZ). She worked as a freelance composer from 1972 until her appointment in 1992 as a professor of composition and music theory at the Prague Music Academy. In 1996 she founded there "Studio N"-Studio for contemporary music, with which she developes a lot of activities Her creative activity is accompanied by compositions for children - choruses, cantatas, successions, instructive compositions - which suggest the authoresses looking for a corrective for her aggressive style. Taking part in a number of composer competitions has brought the authoress outstanding appreciations. At the beginning of her art career she obtained an honourable mention in Mannheim for the compositon Rhapsody in Black. The music of Ivana Loudova finds favour with both interpreters and listeners, it si interested in abroad: a lot of titles have been published by the American houses Schirmer and Peters, some compositions were world-premiered abroad, e.g. in the USA (Chorale - 1971, Hymnos - 1973, Dramatic Concerto - 1980, Luminous Voice - 1986), in Switzerland (Partita in D - 1977), in Italy (Sonetto per voci bianche - 1979).
Selected works: Ballata antica, for trombone and piano; Per Tromba, solo trumpet; Quintetto giubiloso, for brass quintet, Musica festiva, 3 tps, 3 tbs; Cassazione, 4 tps, 4 tbs, tuba; Chorals; Hymnos; Magic Concerto; Concerto for 6 percussionists, organ and concerto band; Luminous voice. Concerto for English horn and concert band, Chamber Compositions Sonata for violin and piano (1960-61), Sonata for clarinet and piano (1963);String Quartet No. 1 (1964);Gnomai, trio for soprano, flute and harp (1970); Air a Due Boemi, for bass-clarinet and piano (1972); Romeo and Juliet. Renaissance suite for flute, violin, viola, violoncello and harp or lute (1974); String Quartet No. 2 "In Memory of Bedrich Smetana" 1974; Partita in D for flute, harpsichord and strings(1975)
Awards: the Arts Prize of Heidelberg; three times she was the winner in the competition Quido d'Arezzo in Italy (1978) with the works Sonetto per voci bianche, 1980 - Benedetto sia il giorno from the Italian Triptych, 1984 - Occhi lucenti e belli; a dozen prizes were won for her choral compositions of the Festival of choral production at Jihlava and in the competition of children s choral production at Jirkov; further prizes she was awarded in the international radio competition in Moscow 1978 (Little Christmas Cantata) and on the Redletter Days of Songs at Olomouc 1983 (Songs about the Rose).
Jeanette Lindström
(born in Ås/Östersund, 1971, resident Stockholm/Sweden), is a jazz vocalist and composer. Lindström's focus is on composing and performing her own material, both music and lyrics, but she has worked in other bands and projects and appeared on several occasions as a featured vocalist with jazz groups, big bands and chamber and symphony orchestras. Lindström has performed and toured throughout the Nordic countries as well as France, Belgium, UK, Japan and Canada. After being awarded the Jazz in Sweden prize in 1995, Lindström recorded her debut CD, Another Country, on the Caprice record label. This recording was followed by I saw you 1997 on the same label. In 1998 she recorded and toured with Norrbotten Big Band, led by trumpeter Tim Hagans in collaboration with pianist Kenny Werner, resulting in a CD with music by Kurt Weill as well as repertoire associated with Frank Sinatra, which was released in 1999. For several years Jeanette worked in a duo along with pianist Steve Dobrogosz. In 2000 they released the CD Feathers, Prophone Records. Her CD Walk was released in 2003 and in 2005 the album In The Middle Of This Riddle was released, both on Amigo record label. These two consist mainly of Lindström's songs. Her first standard album in her own name, Whistling Away the Dark was released in 2006. The song Leaf from the CD In The Middle of This Riddle was remixed in 2007 by the American DJ and producer King Britt, and was released exclusively on iTunes Europe. Another track from the same album was featured on the Saint-Germain des Pres Café – Ladies in Nu Jazz – Volume 7, alongside tracks with Norah Jones, Jamie Cullum, Susi Hyldgaard and others. On her album Attitude & Orbit Control, 2009, Playground Music Scandinavia /Diesel Music, drummer Magnus Öström from Swedish e.s.t. co-produced together with Lindström herself, and he is also playing drums. In 2010, she received a Swedish Grammis for the album within the Jazz category.
Selected works: All the world's a Stage, lyrics by Steve Dobrogosz; White lady in the window, lyrics by Steve Dobrogosz
Selected recordings: Leaf –The King Britt Remixes EP, 2007;
Publications direction: Available at Svensk Musik/Swedmic AB
Awards, selection: 2010, Swedish Grammis in category Jazz Album of the Year for the CD Attitude & Orbit Control.Diesel Music.

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Fireworks - Indiana - Stores
Lowest Firework Prices
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The Indiana source for fireworks at the lowest prices everyday. Shop the fireworks stores online for all your July 4th celebration needs or any event that fills the skies with explosive excitement. Looking for wedding sparklers? Check out the newest member of the family, the "Patriot Stick", This stickless sparklers with be a definite hit. No metal wire to get hot or end up in the lawn. If you shopping for the big fireworks stuff, hit the aerial fireworks repeater department. You will find everything from the newest 200 gram firework cakes like "Pee Ka Boo", up to the maximum loaded 3" fireworks finale cakes, the sky fillers like the best cake on the market "Believe", with its massive spread and earth rocking report . We sell Indiana's number selling fireworks artillery shells at the lowest prices everyday. "Excalibur", on sale, all the time. There is a full selection of skyrockets as well as the traditional "bottle rockets" with a variety of really cool effects. The biggest firecrackers are on the firecrackers page. Like the "Jumbo M-5000" cracker. It will wake the neighbors up in a hurry. Quantity buyers can take advantage of "free fireworks shipping" on their orders as well, which can save hundreds of dollars in shipping cost. . Click on the items below to see a sample of the "Top Selling Fireworks" currently on the market.


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Entails serving as a teaching assistant in a course previously completed with a satisfactory grade. Introduces strategies for the planning, preparation, presentation, and evaluation required for teaching at the college level. Students work with the faculty member teaching the class to develop a detailed plan for participation in the teaching of the class prior to the beginning of the semester in which the course is offered. This course may be repeated if serving as a teaching assistant in a different course.
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Sony Pictures Japan released a new international trailer for Ghostbusters, an upcoming American supernatural comedy film and a reboot of the Ghostbusters franchise.
Directed by Paul Feig and co-wrote with Katie Dippold.
Starring Melissa McCarthy as Abby Yates, a published author on the subject of the paranormal, Kristen Wiig as Erin Gilbert, a professor at Columbia University, who co-authored the book with Yates, Kate McKinnon as Jillian Holtzmann, a nuclear engineer and Yates' new partner, Leslie Jones as as Patty Tolan, an NYC subway worker who stumbles across the main supernatural threat in the film and becomes a new member of the team.
The cast also includes Chris Hemsworth as Kevin, the Ghostbusters' receptionist, Andy García as the Mayor of New York City, Neil Casey as Rowan, a mysterious evil powerful demon, Michael Kenneth Williams, Matt Walsh, & Cecily Strong.
"Thirty years after the original film took the world by storm, Ghostbusters is back and fully rebooted for a new generation.
Director Paul Feig combines all the paranormal fighting elements that made the original franchise so beloved with a cast of new characters, played by the funniest actors working today. Get ready to watch them save the world this summer!"
Ghostbusters is scheduled for a July 15, 2016 release.
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Sustainable fashion, materials and design
As committed yogis it's only natural that our yogi makers put sustainability at the heart of everything they do. They know that authenticity, trust and transparency make for a sustainable business.
They're focused on creating social impact – in the materials they use, the suppliers they choose, and the way they work with other people – collaboratively, transparently and with a sense of freedom.
They're focused on creating social impact – in the materials they use, the suppliers they choose, and the way they work with other people – collaboratively, transparently and with a sense of freedom.
Sustainable fashion
They make on trend yoga pants out of coffee grounds, recycled plastic, organic cotton, bamboo, and hemp.
Sustainable materials
They design beautiful yoga mats that are both sticky and sustainable. They create yoga gift bags out of almond shells. They plant seeds in their hangtags.
Social sustainability
They work with artisan villages in Bali, Nepal and Kerala. They give to charities – every sale helping young women in India, orphaned baby elephants in Africa, and even the stray dogs of Bali.
We connect yogi makers with people who share the same ethics and values, enabling us to better look after each other, the planet, and ourselves.
Urban Goddess is made in fair certified factories from certified organic cotton. Creator Marlene Smits has a recycling collaboration with the Salvation Army; old Urban Goddess clothes that are still wearable go to people in need, and the ones that aren't wearable are used to make blankets for the homeless.
Lo Blasta, creator of Blasta Henriet, only uses Oeko-Tex certified European linen. The linen is printed by a team of craftsmen in London using eco-friendly ink before it's returned to the studio for stitching, filling and packing. Her beautiful recycled packaging is made in England using renewable resources.
FAIR WAGES. Sylvia Daun's belief that dressing fashionably and responsibly goes hand-in-hand means that all Kismet clothing is made out of recycled natural fibres. She works only with small, family-owned businesses that have fair working conditions and pay fair wages.
Starseeds is a slow fashion label. Chief designer Natalia Zawada preserves the beauty of her natural colour palette with slow-dying techniques, using bamboo to create Starseeds' trademark softness, ramie and hemp to createdurability, and a super-cool yarn impregnated with waste coffee grounds to absorb sweat.
COMPASSION. At the heart of Asquith London is Alice's commitment to the yoga principle of Ahimsa - compassion for all living things. All materials are ethically grown, completely chemical free and sustainable.
There is more silver above ground than there is under. That's why Rebecca Joseph works with recycled 925 silver. All her packaging is 100% recycled and she donates to a charity, the David Sheldrick Wildlife Trust, to support orphaned baby elephants.
GIVING HOPE. Free Spirit is ethically made from organic cotton and bamboo in South India. The factory workers are treated well, paid a fair wage, the conditions are clean and safe and the factory gives back to the local community by supporting women and children in need. Founder Christina Gill donates 5% of sales to the HOPE Foundation in Calcutta, helping children off the streets, out of poverty and into education.
Trina and Charlene Solomon work with small-scale producers on beautiful Bali. Touched by the plight of stray dogs on the island, and wanting to end their suffering, SoloSol Movement donates a dollar from every sale to the Bali Dog Adoption and Rehabilitation Centre (BARC).


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News & Events
Delivering wine in stressful times22nd March 2020
In these times of stress and unprecedented adversity many of us have been forced to work from home and/or simply stay... Read More
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We were featured in Square Mile magazine's February edition. Richard told his story of finding wine as a career and finding a... Read More
The Independent Wine Retailer of the Year 2017: Wanderlust Wine20th January 2018
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Włodzimierz Ruka, Piotr Rutkowski, Zbigniew I. Nowecki, Anna Nasierowska-Guttmejer, Maria Dębiec-Rychter
Med Sci Monit 2004; 10(8): LE13-14
Dear Editor,
Gastrointestinal stromal tumors (GIST) compose a recently defined pathological entity, which due to molecular identification of characteristic mutation in c-KIT membrane receptor gene (detected by CD117 immunostaining) and introduction of first effective molecular targeted anticancer agent – imatinib mesilate – tyrosine kinase inhibitor (e.g. c-KIT) has focused attention of oncologists over the world [1,2]. The results of new epidemiological studies suggest that GIST is the most common abdominal mesenchymal tumor with the frequency of 16–20 cases/1 million/year. However, the clinico-pathological features of GIST are not well described. There are some data regarding the associations between GIST and other malignant tumors. The single cases of coexistence of GIST and the renal cancer, cancer of the gall bladder, gastric cancer and lymphoma of the stomach were described [3]. GIST may also occur as a part of other tumors syndromes. The description of so called Carney's triad includes the presence in one patient during his life: gastric GIST, paraganglioma and pulmonary chondromas [4]. GIST may also occur in association with neurofibromatosis type 1. The presence of other malignant neoplasms in the past history of GIST patients may be important issue. We analyzed the incidence of other malignant neoplasms in large group of patients with GIST. We performed a single-institution retrospective analysis of 180 consecutive patients (92 men and 88 women, median age 57 years; range: 19–82 yrs) with GIST treated between September 1999 and October 2003. All pathologic diagnoses were confirmed by positive immunostaining for CD117. During clinical examination all patients were interviewed for past history of other malignancies. Among the 180 GIST patients we found 18 patients with a history of other malignant neoplasms (10.0%). Two GIST patients suffered from more than one other malignancy. Most of these 18 GIST patients had gastric localization (72%), median age was 60 years, there were 8 men and 10 women; 5 cases were inoperable/metastatic (and treated with imatinib – 4 of them responded). Two women had a history of breast cancer (moreover one of them also suffered from chronic lymphocytic leukemia), 2 female patients were successfully treated for renal cell carcinoma, 2 men – for planoepithelial lung cancer and other 2 women – for invasive cancer of the uterine cervix. We also observed: 2 cases of gastric cancer, 2 cases of colon cancer, 1 case of gastric carcinoid, 1 case of the endometrial adenocarcinoma, 1 case of the uterine sarcoma and 1 case of seminoma (third neoplasm – primary spindle-cell bone sarcoma was diagnosed in this patient during imatinib treatment due to GIST liver metastases). In 2 patients treated primarily for GIST of the stomach multiple pulmonary chondromas were diagnosed (Carney's triad). In 4 patients also benign soft tissue tumors (lipomas) were diagnosed. Six cases of non-GIST tumors occurred after diagnosis or simultaneously with GIST. The other metachronous tumors were resected and any patient relapsed. All of these non-GIST tumors were considered sporadic (no family history). Our data are supported by observation of Chacon et al. [5] on smaller cohort of GIST patients, who found also approximately 10% GIST patients with prior history of other solid cancers. A high ratio of other malignancies in GIST patients focused the attention of clinical oncologists on this problem and may imply a common genetic mechanism of their etiology. It is not possible to answer yet if it is the common genetic mechanism or random co-incidence in patients undergone special supervision during follow-up (however, most of these GIST tumors – 15/18 were in high potential of aggressiveness not like the cases found accidentally during the surgery from other indications). Moreover, the fact of this frequent coexistence does not deprive the patient of the possibility of the only effective treatment in unresectable/metastatic GIST – imatinib and it cannot be the exclusion criterion for treatment of recurrent GIST in case of other metachronous malignancy, which had been previously successfully treated.
1. DeMatteo RP: The GIST of targeted cancer therapy: a tumor(gastrointestinal stromal tumor), a mutated gene (c-kit), and a molecular
inhibitor (STI 571). Ann Surg Oncol, 2002; 9: 831–39
2. Miettinen M, Majidi M, Lasota J: Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review. Eur J Cancer, 2002; 38(Suppl.5): S39–S51
3. Antonini C, Forgiarini O, Chiara A et al: Stromal tumor of the ileum (GIST) at the same time as renal carcinoma. Description of the case and review of the literature. Pathologica, 1998; 90: 160–64
4. Carney JA: Gastric stromal sarcoma, pulmonary chondroma and extra-adrenal paragnaglioma (Carney triad): natural history, adrenocortical component and possible familial occurrence. Mayo Clin Proc, 1999; 74: 543–52
5. Chacon M, Roca E, Barugel M et al: Report of solid cancer in patients with gastrointestinal stromal tumours (GIST) Annual Meeing Proceedings American Society of Clinical Oncology, 2004; Abstract 9065,
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Principal Lazaroski completes final year at helm of Mills
New principal appointment expected June 6
May 12, 2016
Lewis S. Mills High School is coming to the end of an era: June 2016 marks the conclusion of Principal Pamela Lazaroski's tenure. After serving Region 10 for 16 years, six of which she spent as principal, the administrator often referred to as Mrs. Laz, is retiring. For Lazaroski, the announcement was no surprise – she had been eligible to retire for several years prior and only just decided she was ready this year. However, the revelation rocked both students and the community.
Senior Jen Merritt says, "I was a little surprised because it doesn't seem like she's been here that long."
While her time at Mills may have felt brief to Merritt, Lazaroski's overall career was incredibly long: she served as an educator at Terryville High School for 26 years. Upon arriving at Region 10 in 2001, she was named the first Dean of Students, as well as the head of the technology department.
Looking back at her career, Lazaroski fondly remembered arriving at Mills in 2001. "My daughter was a senior that year, so I was nervous. She had all her friends and a niche here, and I didn't want to come in as the Dean of Students and ruin her fun, especially since it was her senior year. It ended up being great, though."
In 2007 she was promoted to assistant principal, and finally, in 2010, she was named principal.
Continuing to reflect on her career, Lazaroski felt especially proud of the sense of community she helped foster at Mills, "In a town like Burlington or Harwinton, there aren't many things for teenagers to do, so they really do get involved here. In the spring in particular, you can come to the campus and see students everywhere. You start at the tennis courts and see people playing, go to the baseball and softball fields and find practices or games, see kids running around the track and on the fields, and of course come inside the school and all the club meetings are happening." She continued, "Kids really do gravitate towards the school, and they do a ton of activities here, so I do consider it the hub of the community. It's a very welcoming environment, which I'm proud of."
In addition to extracurricular activities, Lazaroski's pride extends to students for being so dedicated to their studies.
"We've had educators from other districts come, and they'll ask if it's a teacher in-service day because they'll walk through the halls during a class period and see no students," she said. "Kids are where they're supposed to be 95 percent of the time, and that's fantastic. It's very unique to Mills."
Overall, Principal Lazaroski is proud of what she has done. She has no regrets other than that she wishes to see a few projects come fully to fruition.
She said, "There's never enough time. Even though I'm retiring, I still have to be a principal right now and make sure everything is getting done. There have been a few projects I've been working on for years, and I finally feel like they're able to continue without me, but I wish I could see them really come to life."
Assistant Principal Silvia Ouellette, a close coworker and friend to Lazaroski, could not agree more with the retiring principal's sentiments, "I have felt honored to work with her and to be able to continue her work. If one word were to define her, it would be integrity. She is the epitome of integrity and pride and passion in this school. That's what I'll miss most about her- she's also very funny too. We'll be able to carry on because we had her."
On her time working with Lazaroski, Ouellette quotes Isaac Newton, "If I have seen further, it is by standing on the shoulders of giants." In this case, Lazaroski stands as the giant that helped Ouellette and others accomplish more than they thought possible.
When asked about her future plans, Lazaroski is unsure of what she will do, "I'll still be involved in the community and Region 10 and help out if needed. Even though I'm formally out on July 1, it doesn't mean I won't still be here to help transition the new principal over. Plus, I live here, so I'll be at events and games. I have a few different things I could pursue after this, but really my schedule is free. It's kind of overwhelming to go from always having projects and deadlines to just being able to do things on my own time."
The soon-to-be retiree anticipates an adjustment period, but looks forward to benefits of a slower paced daily life.
"I do think I'll finally be able to do those small household chores that I've always pushed off," she laughs, adding: " I'm not sure how many I'll actually do, but some of them are bound to happen."
Summarizing her career, Principal Lazaroski, soon to just be Mrs. Lazaroski, says, "It's been a good run."
Principal Lazaroski will officially retire on June 31, and the new principal will start on July 1. In the meantime, a Search Committee has been interviewing candidates throughout May. Officials anticipate appointing the new principal by June 6.


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"The heart of the wise inclines to the right, but the heart of the fool to the left." Ecclesiastes 10:2
The National Prayer Center is hoping to spark a nationwide revival with its new initiative to pray for and with the country's elected officials. The Josiah Project is named after King Josiah of Israel, who led the nation to repent and pray after finding the Book of the Law.
"He tore his clothes and was convicted before the Lord and he saw the condition of the nation, the culture of Israel was in the toilet. They had pushed God out of the public square. Does all this remind you of something?" Tom DeLay, the former Republican House majority leader who is helping the National Prayer Center head up the effort, told TheBlaze.
Rather than lobbying, prayer intercessors with the Josiah Project will approach members of Congress and state legislatures and offer to pray with and for them, DeLay explained. Chapters will be organized by their congressional districts.
"The Constitution is based upon a higher authority. This government cannot exist in the future if we give that up and put man as the higher authority," DeLay said. "We need that higher authority and the truth that comes from that higher authority in order for us to survive. Otherwise we'll find ourselves where we are where man gets to define what truth is and everything crumbles." here
Tom DeLay is a 'good man', as 'good men' go. One little fact to back that up is his involvement now to pray with politicians, who are in dire need of Godly direction. Another is has unmitigated success as a Congressional Leader. So successful was he that the Democrats went above and beyond to get rid of him, permanently (literally, as Democrat District Attorney Ronnie Earle in Houston went through 12 Grand Jury's til he found one that would indite this man. The unjust and incorrect guilty verdict was eventually over turned, the Judge finding no evidence in the case. Wow. The lengths Democrats go to is frightening:Story here) . . . but I'm digressing . . . .
The only qualm I have is in Mr. DeLays wording. It's not a "higher authority", which is a silly as the term "higher power". Come on. Either say GOD or say naught. If God, the Lord, or Savior is offensive (and it will be), so be it.
There is no "higher authority" than the Creator God and Savior of His creation. If anyone rejects prayer to the Lord Jesus Christ, then he has rejected all that saves mankind anyway. Allah is non-existent (although, the devil is real… and he seeks worship); there is no other god nor gods to pray to or offer worship or sacrifices. Not a single 'religion' will save a single soul. Not one good work or special deed. Whether Jew or gentile, pagan or heathen, whether worshiping allah or following buddha — theses prayer get you know where but hell, and certainly no answers or blessings.
Our Lord knows politicians or political leader from city government throughout the halls of the Capital, and especially within the White House, need prayer and direction. It appears most of the time, these people are looking to their our souls for ideas and agendas instead of seeking wisdom from the wisdom giver.
'Good luck' and blessing, Mr. DeLay and all in the "The Josiah Project". I think our time might be very short to repent and turn to Him for direction. In any case, may God direct your path and be a light unto your feet . . . and come quickly Lord Jesus.
Eph. 2:8-9 – "For BY GRACE are ye SAVED THROUGH FAITH; and that NOT OF
YOURSELVES: it is the GIFT of God: NOT OF WORKS, lest any man should boast.", Rom. 4:6-7; Rom. 10:3 ; Rom. 5:17 ; Rom. 5:18


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These snaps are as light as air! A tasty shortbread cookie blanketed in a powdery sugar. Inside is delightful snap of key lime.
Unit Weight: 8 oz.
Brand: Flathau's Fine Foods
Flavors(s): Key Lime
Color: Green
Shelf Life: 6 Months
Dimensions: 9"H x 3.5"W x 3 "D
Case Pack Size: 6


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Businesses are bust, bosses aren't hiring and too many graduates are clogging the employment sector – but there's one industry still moving from strength to strength.
It's the beauty industry, and it's set to make more than $265 billion in 2017.
And it's not all about leggy blondes gliding down catwalks. From small boutiques to purveyors of fine fragrances, a budding graduate can easily make their mark in beauty – even if they have to start at the bottom of the ladder.
Whether you've got a degree in accounting, management or the fine arts, the world of coiffuring, cosmetics and clothing could make you millions.
So, what positions could you enjoy if you want to become beauty royalty? (more…)
Top Internships for Students
Popular Jobs for Recent Grads
Jobs in Growing Industries


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Everything is quite simple. Marriage registration between foreigners in Ukraine is a legal, easy, fast and fairly cheap procedure.
The accent. This "legal advice" is more useful for those couples, in which both are foreigners and both do not intend to obtain a residence permit or citizenship in Ukraine as a result of such a marriage.
The reasons. In practice, more and more foreigners are registering marriage in Ukraine for very noble reasons, for example, with the goal of adopting a child in Ukraine.
According to the provisions of Articles 211, 212 of the Family Code of Ukraine, a capable person must be at least twenty-one years old to become the adopter of a child, except when the adopter is a relative of the child. A foreigner must be married to become the adopter of a child, except when the foreigner is a relative of the child.
Another fairly common reason is the intention of the couple to use the services of surrogate motherhood after having their marriage registered. Although, only few are aware that in Ukraine, unlike in many other countries, in particular, Germany, France, Italy, Belgium, India, the surrogate motherhood is allowed. And, in view of that, the Ukrainian market for assisted reproductive technology is highly developed.
As stipulated in Article 123 of the Family Code of Ukraine, the spouses, who conceived a child with the help of assisted reproductive technologies, are the parents of that child, not the woman, who became a surrogate mother.
Also, the reason for the marriage registration in Ukraine is a banal desire to avoid various restrictions, for example, age-related requirements, lengthy procedures for collecting documents and obtaining official permits, as well as the need to observe special conditions for marriage in the jurisdictions of the future spouses' place of residence.
The situation in other countries. In order to officially register the marriage of a couple, in which one or both are non-residents of the country of marriage registration, for example, in France, you should first live in the country for at least three months and, then, face very undemocratic prices for wedding services. In a number of countries, for example, Germany, Great Britain, you need to obtain a "bride / groom" visa, having waited for it approximately 2-6 months (one should bear in mind the probability of not obtaining such a visa), and to speak the state language.
As for the marriage registration procedure in the CIS countries, its efficiency also leaves much to be desired, since the marriage registration takes place, as a rule, not earlier than one month after the submission of the appropriate application by the couple to the state bodies.
Furthermore, to register a marriage in Spain, you should have a bank account and real estate in this country. I will not even mention the countries, whose legal system is based on Sharia law, where the traditions of marriage and the preceding rites have their own specific characteristics.
The choice is yours, but in this case, Ukraine is a good choice.
The rights of foreigners and stateless persons in Ukraine. Foreigners and stateless persons have the same rights and freedoms as nationals of Ukraine have, unless otherwise provided by the Constitution, laws of Ukraine, as well as international treaties, to which Ukraine is a party, as stated in Article 2 of the Law of Ukraine "On the legal status of foreigners and stateless persons". Article 18 of this law establishes that foreigners and stateless persons have equal rights and obligations with nationals of Ukraine in marriage and family relations.
The conditions, the observance of which is necessary for the registration of marriage in Ukraine. According to the general provisions of the Family Code of Ukraine, the marriage age in Ukraine for women and men is set at 18 years. Upon the request of a person, who has reached the age of 16, he/she may be granted the right to marry, if it is determined that such a marriage meets his/her interests. Other conditions that must be met for state registration of a marriage are 1) monogamy, that is, a woman and a man have the right to remarry only after having terminated their previous marriages; 2) persons, who are relatives of a direct line of kinship, siblings, cousins, aunt, uncle and nephew, niece, adoptive parent and adopted child cannot be married to each other. Generally speaking, these are the all conditions.
The procedure for registration of marriage in Ukraine. In order to register a marriage in Ukraine, a woman and a man must submit an application to any state registration authority of their choice or to another institution that provides public services.
The couple should additionally provide the following documents, certified in the prescribed manner and translated into Ukrainian: the first page of the passport; the document confirming the dissolution of the previous marriage (if any). In this case, a copy of the above documents certified by a Ukrainian notary shall be deemed as documents, certified in the prescribed manner, except when legalization (apostilization) of a foreign document is required (for nationals of countries, which are not parties to the Minsk Convention on Legal Assistance and Legal Relations in Civil, Family and Criminal cases of 1993 or to the Hague Convention Abolishing the Requirement of Legalization for Foreign Public Documents of 1961).
After the authorized body accepts the documents, they are transferred to the migration service to check the legality of the foreigner's stay on the territory of Ukraine. The duration of such a verification is on average 5 working days, and sometimes even less. Upon obtaining the results of the verification, the marriage may be registered and, then, attested by a marriage certificate.
Thus, you do not have to live in Ukraine for a certain period of time before you may apply for registration of marriage, there is no need to obtain visas, other official permits or to have real estate in Ukraine and so on.
The registration procedure, including the preparation and submission of documents, the migration verification and marriage registration, may take you about 10 working days. And in this, you will encounter no high costs, no bureaucratic system or paperwork.
By Daryna Demchuk, Associate Integrites


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Wild Alaska Wolf Diamond Pendant GRP279WGND
- Product Details Below:
Product Details:
Diamond Information:
Total number of Diamonds: 1
Diamond Cut: Round
Setting type: Prong
Diamond Total Weight: .19 dtw
Gold Nugget Information:
Total number of Gold Nuggets: Several
Pendant Information:
Style number: GRP279WGND
Metal: 14kt white gold
Length: 32 mm
Width: 25 mm
Pendant Approx. Total Weight: 9 grams
Delightful ♦ Alaskan ♦ Enchanting
Our medium sized Alaskan Wolf Pendant handcrafted with natural Alaskan Gold Nuggets and a brilliant Diamond in 14kt White Gold.
The chain displayed in the picture is a wheat chain which you can select from the drop down option above. The wheat chains you can choose from are all solid 14Kt gold and are the strongest we have found in the industry. If you have questions or would like to order a different size, please call us at 907-456-4991.
Note: Jewelry prices and availability are subject to change without notice.
View our "Terms and Conditions" if you'd like more information.
View our "Terms and Conditions" if you'd like more information.
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The Oracle Of San Quentin.
Curtis "Wall Street" Carroll overcame poverty, illiteracy, incarceration and a lack of outside support to become a stock investor, creator and teacher of his own financial literacy philosophy. The media gave him the moniker the "Oracle of San Quentin" for his stock market prowess and ability to translate financial information into simple language for his students.
Carroll, grew up in a life of poverty, in an interview with VladTv, Carroll says: 'the people who told me I should be in school were the same people who sold me drugs, and of his role models they were 'the dope dealer who pulled up in a Bentley'. Many of Carroll's family members were addicted to crack cocaine, which led to bouts of homelessness. He says he first grew disillusioned with the world when he witnessed his mother stand in line at a blood bank to sell her blood so she had enough money to feed her children. To escape his life of poverty, instead on turning to the books, he turned to crime to 'get paid'. He sold drugs, stole cars, burglarised homes, stole welfare checks and committed robberies. In 1996, at 17 years old, he committed a robbery where a man was killed. He turned himself in and ended up an illiterate teenager in prison with a 54-to-life sentence.
However, it would be prison that would turn the former Saul into Paul, whilst incarcerated at age 20-21, Carroll decide to combat his illiteracy and learn how to read. It's here that Carroll finally learnt about the stock market, his role models changed from the Bentley driving drug dealer from his city to Wall Street legend Warren Buffet.
Carroll with his new-found skill of reading found out that over 60% of the American population had less than $1000 in savings, 60% of NBA and NFL players lose their millions by the time they retire and 40% of marital problems derive from financial issues. In a TED talk Carroll criticised the current economic climate most people are trapped in.
"Financial illiteracy is a disease that has crippled minorities and the lower class in our society for generations and generations, and we should be furious about that. Ask yourselves this: How can 50 percent of the American population be financially illiterate in a nation driven by financial prosperity?"
Carroll now provides a course for inmate and members of the public to become financially free, he calls it the FEEL system. This stands for Financial Empowerment Emotional Literacy, it's a program that helps people distinguish between emotion and finance. Carroll argues most decisions people make are heavily influenced by people frivolous spending habits. "You mean to tell me that people worked their whole lives, buying cars, clothes, homes and material stuff but were living check to check?"
Carroll's reincarnation is a very inspirational story to those who were on the wrong path but learnt from their mistakes. Carroll never blames his upbringing for his involvement in crime, he blames himself for thinking that was the only way out when he had other options. Carroll maybe released within three years, if his parole request is granted and we could be seeing more of the self-made wall street guru.


text: After the success of my eyelet messy bun hat pattern, I'm please to bring you my latest pattern! The eyelet wrist warmers coordinate with the messy bun hat, and the set would make a super cute gift this holiday season. The pattern includes adult, toddler and child sizes. Knit up in worsted weight yarn, they are a quick and satisfying project! The pattern is available for download from Ravelry. Thank you for your patronage!


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Win: Flora and Henri dress worth $168
Happy Thursday all! We have a special treat for you today.. we have not done a giveaway in awhile so this time we have teamed up with our friends over at Flora and Henri.. they are very kindly giving away the pretty Eloise dress to one lucky winner. The dress is available in sizes from 3 years to 10 years.
With the heat of the summer upon us, dresses are really the best way to go. Not only do they give breathing room, they look chic whatever the occasion is, so you can be sure the little one will feel comfortable but still look nice for that important tea party she has scheduled for 3pm with Mr bear, Ms rabbit and friends!
What you can win : Flora and Henri Eloise dress in Peach worth $168
What you have to do: Repin the image above on to your pinterest board and leave a comment below with the name of the little lady you think this dress would be perfect for. Make sure to leave the link to your pinterest board in the comment as well..
We'll choose a winner in a week, on 23 July 2015 and contact you, whomever the lucky person is, via email!
The entire Flora and Henri collection has something for everyone, the boys, the babies, the girls. Even the cool moms! You are going to love their Flora Femme collection.. we are already drooling.
{ Striped boatneck ; Baby jean in bright denim ; Ripped baby leggings ; Embroidery blouse set}


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Raw + Rice
After cementing its place as the spot to go on the Sunshine Coast if you're a die-hard poke lover, Raw + Rice made its way to Brisbane in 2019, opening a chic and minimal spot in California Lane. At Raw + Rice, poke is where the menu starts and ends, but the scope for malleability is large. Diners can pop in and select from one of the suggested bowl combos, or opt to build their own. First, select a base (sushi rice, brown rice, quinoa or mixed greens) then follow it up with your protein of choice – we're talking salmon, tuna or ocean trout (depending on seasonal availability), white fish, soy tofu or poached chicken. Once the essentials are locked in, get creative with 'the freshness' – avocado, red onion, carrot, edamame, wakame, coriander, bean sprouts and much more. The final touches are then added, including sauces such as sesame tahini, ponzu, wasabi mayo or tamari, as well as a bit of crunch from the likes of wasabi peas, crisp shallots, sesame seeds, tobiko or nori. Once you've got the perfect poke bowl, you can pair it down with a kombucha, Carton & Co. water, an ice-cold Karma Cola or a fresh whole coconut. All packaging comes from BioPak, which specialises in biodegradable products made from mulched sugar cane. Additionally, Raw + Rice chooses to pluck its staff from the local communities, engaging with schools to provide employment opportunities and training to kids looking to build their resume.


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So Flare lets us embed Mimic project files in our help system topics that compile when we render HTML5 help output. The resulting video displays inline in the output. However, every time I try to do this, I get the following error: System.NullReferenceException occurred at 7/29/2019 12:48:45 PM Object reference not set to an instance of an object.
As I understand it this is a legitimate Windows error event that Flare will just sort of throw every time something it doesn't understand goes wrong.
I WAS eventually able to successfully embed Mimic projects in the Flare topic by handcrafting the appropriate code, and the output works just fine. And, per the title of the post, this error only happens if the Mimic project contains interactivity - if it's just a video with no input for the user, then it embeds just fine with the normal Flare menus.
Does anyone know for a solution to/workaround for this? My team isn't as used to poking around the guts of Flare content as I am and I don't want to hand this down as the official process for embedding Mimic stuff if there's a better way.


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More About Domino's on Highway 82
Domino's: We're Reinventing Pizza at 919 Highway 82 W
When you're craving a heavenly slice of cheesy, meaty, veggie-loaded goodness, we know your tastebuds don't want just any old pizza in Greenwood. You're looking for a delectable pizza with a freshly made tomato sauce, perfectly sliced bits of pepperoni, generous piles of mozzarella and parmesan, and a golden-brown crust that's both crispy and chewy. You want to take a bite out of the perfect pizza. You want Domino's.
At Domino's on Highway 82, it's never been easier to get the fast and fresh pizza your tastebuds are begging you for! Call (662) 455-3030 to order your pizza over the phone, go online, or stop by to place a takeout order.
First, start by selecting from one of our handmade crusts, like our hand-tossed crust that's packed with buttery flavor, a pan crust featuring two colossal layers of cheese, a crunchy thin crust, or even a gluten-free pizza crust! Next, pick your sauce and load up on your favorite, most delish toppings. Whether you want to combine sausage, bacon, salami and green peppers, or stick to a blend of cheddar, mozzarella, feta, and asiago cheese, your neighborhood Domino's has it all!
We've got slices to suit any taste. How do we know? Because there are more than 34 million ways to craft a single Domino's pizza. Customize your pizza from bottom to top or choose from one of our chef-inspired specialty pizzas, like the popular Wisconsin 6 Cheese, Pacific Veggie, or ExtravaganZZa™, and have it delivered to your doorstep, super fast!
Order Greenwood Pizza Delivery Near Highway 82
When you order from your Highway 82 Domino's, you'll see that we're pretty serious about pizza delivery. In fact, we're so serious about it that we promise your pizza will arrive piping hot and freshly made, right from our oven to your door. Want to see how fast we can deliver? After you place your order, use our patented TrackerⓇ to stay up to date on the status of your pizza order. Follow it from the moment the sauce is added to the second it leaves our door for delivery... and try to keep your drool from falling onto your keyboard or phone in the meantime.
Call (662) 455-3030 or order pizza delivery online now! Why keep your hunger waiting any longer?


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Art Focus host Amanda Clem speaks with Portland artist Alyson Provax about her artistic practice, The Bachelor, and her exhibition you i everything else — on view at Wolff Gallery May 2nd - July 1st, 2018
ARTISTS STATEMENT: you i everything else
Sometimes I have the feeling that my experiences are not fully my own, that I have borrowed feelings from the past. This has lead to a personal interest in epigenetics as I search for the parts of myself that are relics from the experiences of my ancestors or my earlier self. A similar phenomenon is visible on The Bachelor: current contestants repeat the words and phrases of past contestants, experiencing the others' feelings. I think we watch these shows because of this repetition and the comfort of that predictability. In 1993 David Foster Wallace wrote about the irony of being told to "act natural" on tv because acting as though you are not being watched is a learned skill. We've spent the intervening 25 years collectively practicing this skill, and as a culture are now much better at acting natural.
To paraphrase Olivia Laing, loneliness exists not in solitude but in concealment. The idea that we should be a consistent and watchable self is a form of this loneliness. We are all inconsistent, the individual self is neither static nor true.
Alyson Provax is a printmaker and an animator. She was born in California in 1984 and lives and works in Portland, Oregon. She has shown regionally at Wolff Gallery, Upfor Gallery, Bridge Productions and the Whatcom Museum, nationally at A.I.R. Gallery and The Untitled Space in New York, and internationally at the Blueproject Foundation in Barcelona. Her work appeared in articles about artists' responses to the 2016 election in New York Magazine, Newsweek, and ArtSlant. In May 2018 her work will also be on view as a part of A LONE curated by Vignettes and Gramma in Seattle.


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Liposuction – Is it a long term cure for American Obesity Problem?
Liposuction – Is it a long term cure for American Obesity Problem?
To answer this question, we need to first understand what liposuction is. Los Angeles Liposuction experts contend that while liposuction is obviously not the first option when it comes to reducing fat, sometimes exercise and diet are not enough, and there are some stubborn areas of the body which require more drastic measures. Men and women tend to store fat in different areas. Men often put extra weight around their love handles and abdomen while women tend to gain it around their thighs and hips. Liposuction Los Angeles clients mentioned that the procedure provides selective removal of fat and therefore sculping the body in ways not possible by other means.Butt LiftBrazilian butt lift is an exciting new plastic surgery option getting popular with Los Angeles Butt Lift customers. In Los Angeles Buttock Lift and Liposuction combination is often preferred. Can a person regain fat in areas that were Liposuctioned? Most likely the answer is no. This is because fat only gets deposited into fat cells. Because Liposuction removes fat cells from the areas that were suctioned, new fat cells will be deposited in other areas of the body. This is not a big issue unless a person gains significant weight. The tighter and more elastic a person's skin is the nicer and smoother result they can expect with Liposuction.Liposuction can be performed all areas of face, neck, chest, abdomen, flanks, back, arms, buttocks, thighs, calves and ankles. Liposuction Los Angeles renowned expert Dr. Younai is board certified Plastic surgeon who receives patients at the California centre for plastic surgery from the Northern as well as Southern California region. Some of these cities include. Beverly Hills, Los Angeles, Santa Monica, Hollywood, Burbank, Sherman Oaks, Encino, Calabasas, Woodland Hills, Thousand Oaks, Westlake village, Pasadena, Glendaale, Valenica, Palmdale, Fresno and Oxnard.
Liposuction – Is it a long term cure for American Obesity Problem?
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This post on health related topics was brought to you by HealthCheckr.com – be sure to flick around and find something you like.
HealthCheckr has articles on Acne, Alternative Medicine, Beauty, Cardio, Depression, Diabetes, Disease-Illness, Fitness-Equipment, Hair-Loss, Health-Fitness, Medicine, Meditation, Mens-Issues, Muscle-Building, Nutrition, Supplements, Weight-Loss, Womens-Issues, Yoga


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How to live like a creative: a step-by-step guideAUTHOR: Desktop
Online platform for creatives Format reveals survey findings on how to live like a creative.
What do creatives do all day? How much coffee do they drink in a day? How do they end their day? How do they work? Do they own a pet? These questions and more are answered in a survey conducted by online platform Format.
Format collaborated with illustrator Sam Island to visualise the key findings and illustrate the respondents' daily habits, hour by hour.
More than 2000 of the site's members were surveyed and they revealed that "67% of creatives like to drink coffee" and half of the respondents own a cat or a dog, and "48% own a leather jacket".
There are a number of interesting findings for productivity, too. 20% of those surveyed saying they "find themselves to be most creatively productive during the late morning, between 10am to 12:59pm," and another 20% "most creatively productive during the night, between 9pm and 11:59pm."
Also, to note: "The tears of joy was respondents' most used emoji in 2015″.
How does your day match up to the findings?
See the full survey findings here.


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Do you like sports? What about hats? If you said yes to either or both of those question then you might want to pay close attention to the next auction taking place at the end of this month in Dayton, New Jersey. This live auction consists of 34 baseball caps in total. Among the lot your find caps of popular baseball, football, and basketball teams. Some of these caps as logos of college teams and others are of the big leagues. Ther hats all appear to be in brand new or excellent condition. Normally each one of these caps would cost you a pretty penny in stores, but if you attend this upcoming live auction, be prepared to save big! To learn more about this bulk auction and others just like it being held on the same day, simply click here to being your 3 day free trial account.
Posts Tagged with 'caps'
Lot of Various Sports Team Logos Baseball Caps: Show Your Love of the Game
Tags: baseball, baseball caps, caps, fashion, football, hats, seized caps, seized hats, sports
Posted in Live Auction, Live Auction Items, Seized
Hats, Sweaters, Pants: All For You!
If you are looking for a variety of clothing then you should check out this current online auction for a lot of Hats, Sweaters, Pants and more clothing! All of these clothes look pretty good and seem like they are in great shape. If you are looking for a nice amount of clothes for you to take home or resell then this would be it. Let's say you own a clothing store and are looking to stock your shelves with a quantity of new items. You would have definitely come to the right place and the best part is that you wouldn't even have to leave your home in order to bid on this lot of items. This whole lot of clothes is located in Virginia and can be shipped out to you when you win or you could very well pick them up from the auction site. The current bid on these clothes is only $85 with the auction ending extremely soon. You can find out more about this lot of items and about many more by clicking here.
Tags: baseball caps, caps, clothes auction, clothing, hats, pants, sweatpants
Posted in Online Auction Items, Seized


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N Holder (Navy)
/count/ sold in last /time/ hours.
N holder is a stylish accessory for Neo smartpen N2 & M1, enhancing the convenience of note-taking. Users can slip their business cards, pen t...
N holder is a stylish accessory for Neo smartpen N2 & M1, enhancing the convenience of note-taking. Users can slip their business cards, pen tip and other necessities on its left side, while N2 & M1 fits perfectly in the center. On the right side, users can fasten N memo or pocket notebook. In short, N holder is a must-have item for Neo smartpen users.
- N holder(115X170mm) is a stylish accessory for Neo smartpen.
- Carry around your pen, N pocket or memo notebook, pen tip, business cards and other necessities with N holder.
- One N memo notebook is included in each N holder package.
Product info
Navy / 115mm X 170mm / PU + SUEDE + PVC
- International buyers are responsible for all duties and taxes.We'll ship items in 1-2 business days after receiving payment
- We ship with USPS, K-packet (Korea post, EMS) UPS and DHL
- Shipment Transit time
Expedite Shipment
(DHL, Fedex)
Economy Shipping
Korea post
Asia 2 - 5 days 5 - 7 days USA/ Canada/ EU 3 - 6 days 7 - 15 days
- Buyers are responsible for paying import fees including duties and taxes. It usually as part of clearing their parcel through customs,
or when they receive their item.
Kindly note that EU country import around 20% of VAT for each shipment.
- In case you received a defective or wrong item, the customer has up to 3 days from date of receipt to request for refund or exchange for a new one
- We do not allow refunds or exchanges because of change of mind. Please read all description provided as a guide before you bid. While every step has been taken to ensure that we ship out correct item, there will be occasion when you receive items that are different from the description. In such case, we ask that you contact us immediately so we may remedy the situation.
- For any return or customer support issue, please contact email@example.com


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Durable WPC Sheet for Decking
Durable and Eco-friendly WPC Decking
Our high-quality WPC Decking boards are manufactured from 60% recycled hardwood fibre and 40% recycled plastic, and are an ideal choice where weather resistance and durability are required. It is eco-friendly and long-lasting, and is easy to clean and maintain. WPC Decking boards manufactured by us are extremely hard wearing and do not absorb water or fade in colour or attract mould. It will not split, crack or warp, and can be worked like timber using woodworking tools. WPC Decking is available in attractive colours and can be used for landscaping or exterior decoration.
Other Applications
Products - WPC Sheet
At Plastimber Impex, we have gained huge recognition as a prominent WPC sheet manufacturer in India, offering finest quality products that are fabricated in compliance with latest industrial regulations. The Wood Plastic Composite sheets are accurate in dimensions, highly robust and precisely finished. Being a leading WPC sheet manufacturer in India, we ensure that the sheets are carefully examined at all stages of production to deliver defect free, high quality products to our customers.


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The following Employment Tax guidance note by Tolley in association with Karen Cooper and Jeremy Cavendish, Cooper Cavendish LLP provides comprehensive and up to date tax information covering:
If a company is operating any tax-advantaged share scheme or arrangement (including EMI), it is required to make an online annual return by 6 July after the end of the tax year in which the scheme or arrangement was registered and each tax year during the life of the scheme or arrangement. This includes where the company is making a nil return (see below).
HMRC's 6 July deadline is a strict one and failure by a company to make the relevant annual return and / or declaration will have serious consequences, including penalties and, in respect of certain tax-advantaged schemes, the loss of tax relief.
It is therefore essential that companies operating these types of schemes are familiar with and fulfil their compliance obligations. HMRC has no obligation to issue reminders to a company about making its annual return(s). It is therefore important that the company is prepared to make the annual return(s) on time. The person responsible for making an annual return submission may find it helpful to set electronic calendar reminders in the period leading up to the deadline.
The company needs to use HMRC's ERS service to file annual return(s). The company will not be able to file an online annual return until the relevant scheme or arrangement has been registered with HMRC and the scheme or arrangement having been issued with a unique scheme reference number (see the Registration and self-certification of tax-advantaged share schemes guidance note).
HMRC strongly recommends that a company uses its templates as this will limit the margin for error and rejected filings as a result, but it is possible for a company to create its own template and HMRC has produced technical notes to support a company in this process. These are available for each tax-advantaged scheme and can be accessed by clicking the
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Notes, Exercises, Videos, Tests and Things to Remember on Ecological imbalance and their consequences
Please scroll down to get to the study materials.
The greenhouse effect refers to circumstances where the short wavelengths of visible light from the sun pass through a transparent medium (i.e. envelope of gases CO, CO2, SO2, etc.) and are absorbed, but the longer wavelength of the infrared radiation from the heated objects are unable to pass through that medium and are trapped causing more heating and a higher resultant temperature.
The causes of greenhouse effect are as follows;
The ozone layer is a deep layer in earth's atmosphere that contains ozone which is a naturally occurring molecule containing three oxygen atoms. An essential property of ozone molecule is its ability to block solar radiations of wavelengths less than 290 nanometers from reaching Earth's surface. In this process, it also absorbs ultraviolet radiations that are dangerous for most living beings.
In the stratosphere, the CFCl3 is broken down into chloride atoms in the presence of UV radiation. Each chloride atom reacts with more than 10,000 atoms of O3 converting into O2. Here, produced chlorine atom can destroy other molecules of O3.
Acid rain is a rain or any other form of precipitation that is usually acidic, meaning that it have the higher number of hydrogen ions (low pH). Normal or unpolluted rain has a pH of 5.6%, the acidity is due to the presence of CO2 in the air. But acid rain has a pH value of 4 to 4.5 that is due to SO2 and oxides of nitrogen present in it.
Oxides of sulphur and nitrogen (SO2, NO, NO2 ) are the main air pollutants produced mainly by the combustion of fossil fuels for power generation.
In the atmosphere, SO2 and NO2 react with moisture forming respective acids (H2SO4 and HNO3 ) which then dissolving in water vapor in atmosphere fall onto the earth as acid rain. These acidic oxides may even undergo physical and chemical transformations producing toxic agents. About 60% - 70% of acids in the atmosphere are derived by the oxidation and hydrolysis of SO2 and H2S and rest 30% - 40% from various nitrogen compounds and other compounds.
A textbook of biology 8th edition.
No discussion on this note yet. Be first to comment on this note


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Information about the 2020 Stewardship Campaign is here!
Learning and Growing
Giving and Serving
Financially Supporting
Friends in Christ,
I invite you to take a few minutes to view the attached video that highlights one of our many
church ministries in the words of someone very engaged in its execution. The theme at DPC
this year is Engage in the Mission of Christ, the Stewardship theme is "Engaging Generosity." As
you listen to fellow church members share the joy of engagement and the role generosity has
played in their faith walk, I hope you are inspired to consider new ways you might further
Engage in the Mission of Christ.
Enjoy the Journey!
Scott Overcarsh, Stewardship Council
"Let us not love with words or speech, but in action and truth." I John 3:18
In order to fulfill the mission to which God has called us, the time, talents, and financial resources of all of us will be needed. Important ministries within our congregation, in the greater Decatur community, and with our global partners depend upon our faithful and generous giving.
Please take a few minutes to fill out the below form. There are answer options for each area, just choose the one that best fits your level of interest.
Thank you for supporting the ministry of this church!
Our Mission Statement
The mission of the Decatur Presbyterian Church community is to share Jesus Christ's love for the world.
DPC's Bicentennial Goal
Every child of God – belonging, engaging, being transformed
Core Strategies
1. Engage people of all ages in high quality experiences of worship and faith formation
2. Implement courageous outreach efforts that engage new people with the church community
3.Care compassionately for those struggling with life circumstances, including those living on the margins of society
4.Intentionally build relationships within the church community


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IndependentSee below for a list of excursions of this travel style
Are you more of a free spirit who likes to be the artisan of your own destiny? This type of trip allows travellers to experience destinations at their own pace. They do not involve a guide or a host or a set routine of daily activities. Great Excursions presents this option to people who like to create their own journeys, once they have decided which course they aspire to follow.View all Travel Styles
Privacy Policy Top of Page


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3-DIY: Stereoscopic Moviemaking on an Indie Budget by Ray Zone
English | 2012 | ISBN: 0240817079 | ISBN-13: 9780240817071 | 408 pages | PDF | 306 MB
A must-have read for anyone looking to take their independently-produced film or video into the 3rd dimension. The text features technical, practical, and inspirational insight from the visionaries who've been producing 3D film and video for decades, not just in the recent past. They offer low-cost techniques and tricks they've been implementing themselves for years. A variety of styles are discussed, from full CG to time lapse - even a film made during a freefall skydive jump!
The filmmakers discuss
* Options for on-set playback
* Preparing for final playback in various formats
* Adapting existing technology to your needs
* Post production software choices
* Working with computer graphics in 3D
This book includes 3D glasses and a companion YouTube channel featuring the work of the filmmakers featured in the book (which you can view in 3D with the glasses), as well as the opportunity for you to upload your own videos for critique and feedback from the author and others.
3D glasses are not included in the purchase of the e-book of 3-DIY.
Download Rapidgator.net
Download Letitbit.net
The filmmakers discuss
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STOCKHOLM (Reuters) - Nordea NDA.ST is to cut at least 6,000 jobs after saying it would miss its 2018 cost target.
The Nordic region's biggest bank, which has invested heavily in IT over the last three years, said automation and digitalisation meant it would shed at least 4,000 of its 32,000 employees and some 2,000 consultants.
One in five of Nordea's customer meetings is now held online and the bank has introduced an artificial intelligence chatbot to answer common customer questions.
"We're becoming more digitalised, more automated," Nordea CEO Casper von Koskull told Reuters.
"This is not cutting cost within an existing structure, we're changing the way a bank works. On one hand it's very exciting, but on the other hand, of course, it results in the industry needing fewer people."
Staff reductions would be spread evenly over geographical regions and business areas and generate a one-off cost of between 100 and 150 million euros which would be booked in the fourth quarter, he said.
"You will see this coming through in pretty much the whole industry," von Koskull added.
However, the market was not impressed with the projected cost savings. Nordea said it saw costs of 4.9 billion euros (£4.37 billion) for the full year 2018 and that it would take a further three years to meet its target of 4.8 billion in annual costs.
Nordea shares were 5.7 percent lower at 1027 GMT, underperforming the European banking index .SX7P which was up 0.1 percent.
"What's surprising is that they cut 6,000 employees, but you see almost no savings. They have so much underlying cost inflation that they have to do this to keep costs at this level," Andreas Hakansson, analyst at Exane BNP Paribas, said.
Nordea posted operating profit of 1.09 billion euros ($1.29 billion) for the third quarter, matching the forecast in a poll of analysts but below a year-ago 1.15 billion.
The earnings report was the Nordic bank's first since it announced it planned to move its headquarters to Finland, sparking fury among Swedish political leaders and labour unions.
The move, aimed at cutting the cost of complying with Swedish regulations, is the first time since the financial crisis that a major bank has shifted headquarters to avoid tougher rules.
Reporting by Johan Ahlander; Editing by Niklas Pollard/Edwina Gibbs/Alexander Smith


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- Release of YES BANK – TERI study 'Electric Mobility: Achieving a Paradigm Shift', at World Sustainable Development Summit 2018
Delhi, February 16, 2018: YES BANK, India's fourth largest private sector bank partnered TERI (The Energy and Resources Institute) as Banking Partner for the World Sustainable Development Summit (WSDS) 2018 in New Delhi.
The joint initiative outlines key findings, including front runners in adoption of Clean Energy, basis ease of scalability and preferred mode of transport, and the convergence of the 'Make in India' initiative together with Green policy interventions and Green bonds to make EV a transport reality in India. This is in line with the Government's ambitious target of achieving 100% electrification of transport by 2030.
L – R: Dr. Ajay Mathur, Director General, TERI; Rana Kapoor, MD & CEO, YES BANK; Shri Anand Kumar, Secretary, Ministry of New & Renewable Energy; Shri Jayant Sinha, MoS for Civil Aviation; Shri Upendra Tripathy, Interim DG of International Solar Alliance
Hon'ble PM Shri Narendra Modi delivered the Inaugural Address on February 16 and stressed on re-enforcement of India's commitment to work towards a sustainable planet, for present and future generations. The PM highlighted India's steady progress on creating a carbon sink of 2.5-3 bn tonnes of carbon dioxide equivalent by 2030, a mighty feat. As the world's fastest growing major economy, the PM spoke about India's immense energy needs, expected to be met by 175 GW Energy from renewable sources, by 2022.
The Summit also witnessed participation from Shri H.S. Puri, Minister (IC) for Housing and Urban Affairs; Shri R.K. Singh, MoS (I/C), Power & Renewable Energy; Shri Jayant Sinha, MoS, Civil Aviation; Dr. Harsh Vardhan, Union Minister, Ministry of Science & Technology, Ministry of Environment, amongst a host of other National and International decision makers.
Commenting on this occasion, Rana Kapoor, MD & CEO, YES BANK, said "Electric mobility landscape in India is currently at a nascent stage, with India requiring nearly 8 times the existing global stock of EVs. There is an urgent need to scale creation of an enabling infrastructure. This ambitious target will provide the much required thrust to make Electric Mobility a programmatic reality in the near future."
YES BANK believes that as a financial institution, there is an inherent need to play a leading role in India's development. Since its inception in 2004, YES BANK through its 'Responsible Banking' ethos has believed in creating sustained value for its stakeholders, through social, economic and environmental dimensions. Integrated with core business strategy, Responsible Banking steers the sustainable development agenda at YES BANK through its pathways of Social & Developmental Impact, Climate Action, and Transparency & Disclosures.
About YES BANK
YES BANK is a 'Full Service Commercial Bank' providing a complete range of products, services and technology driven digital offerings, catering to Retail, MSME as well as corporate clients.
YES BANK operates its Investment banking, Merchant banking & Brokerage businesses through YES SECURITIES and its Mutual Fund business through YES Asset Management (India) Limited, both wholly owned subsidiaries of the Bank. Headquartered in Mumbai, it has a pan-India presence across all 28 states and 8 Union Territories in India including an IBU at GIFT City, and a Representative Office in Abu Dhabi.
For more information, please visit the Bank's website at http://www.yesbank.in/
Alisha Prakash
Email: email@example.com
Jyothi Goswami
Email: firstname.lastname@example.com


text: Edit Post Delete Post #Griffinsnation Oct. 2, 2019 Established in 1962 Eric Hamber Secondary boasts one of the most successful and well-rounded athletics programs in the City.Offering over 35 athletics boys and girls teams per school year at all grade levels. Eric Hamber provides the greatest variety of school sport opportunity for students in Vancouver. Last year over 500 student-athletes were involved in our programs as players, managers, and coaches.Student athletes over the past 5 years have excelled and been victorious at City, Regional, and Lower Mainland championships in Basketball, Football, Soccer, Field Hockey, Volleyball, Track and Field, Ultimate, Badminton, Table Tennis, Golf, Cross Country, Aquatics and Wrestling. These successes have resulted in Eric Hamber becoming a regular fixture at Provincial Championships.Our student-athletes not only excel on sports fields, courts, tracks, and rinks they are also very successful in the classroom with many having gone on to participate in Collegiate, CIS, and NCAA sport.The majority of our teams are lead by Eric Hamber teachers who volunteer to coach, sponsor, and organize our teams. We are also fortunate to have many excellent volunteer coaches from the Hamber community - parents, alumni, current students and VSB staff that come back and help build meaningful and safe connections with our students.All are welcome in the Griffin's Nation! Share


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I rolled out of Melbourne a year ago on a wicked, satiating road trip to the warmer climes of northern Australia and the time is nigh to do it again.
However this time, I venture South below the mainland to a place I've never visited; Tasmania. I've always been intrigued by its surreal images of nature. The people are always the best of us. Down to earth and proud of their Isle.
It's winter in southern Australia and colder still in Tasmania. I will be roughing it in the back of my trusty old ute ( that's an Aussie pick-up for you foreign readers), for a mere week. Hikes, dirt roads, camping and hopefully some fun and culture in the cities of Hobart and Launceston.
I depart tomorrow evening taking the car ferry (The Spirit of Tasmania) across the wild Bass Strait for who knows what!
I love the mystery and the nerves are kicking in. But I've always felt well guided by the spirit that guides all well intentioned journeyers and I hope I can feed any readers and friends with something insight and beauty as I take the plunge wayyyyyy down again.
Oh and as an afterthought: I go to S.E Asia in two weeks for another journey so the cold will be easy to bare with that in mind.
Peace to y'all.


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Accommodation – Services
Wellness Santa Hotel
Natural beauty and luxury combined
Wellness Santa Hotel is a brand new 5-star hotel in Thessaloniki, located on the iconic beach of Agia Triada in Neoi Epivates, just 10 minutes drive from the airport and 30 minutes drive from the city centre. Featuring an indoor seawater swimming pool and Spa services, Wellness Santa Hotel is the ideal destination throughout the year, offering luxurious accommodation along with exceptional services.
Our classical Mediterranean style rooms have granite & marble bathrooms and original curved wooden bedrooms with elegant embroideries. There is free Wi-Fi, air conditioning and flat-screen satellite TV. There is also an interior atrium lounge area by the lobby bar, a poolside bar and a terrace with lounge chairs.
Eco-friendly & cozy
Wellness Santa Resort is built and armoured seismically, eco-friendly, achieving the highest energy class A+. Energy design of buildings has become imperative in recent years due to the rapid increase in fuel prices, but also the need to reduce produced pollutants.
The overall philosophy of the hotel's energy design is to ensure thermal comfort with the most extensive use of passive cooling and heating systems. By minimising energy requirements for heating, cooling and hot water and by covering the required loads using renewable energy sources, maximum fuel economy and minimal environmental impact are achieved.
For this purpose, there have been installed systems that utilize practically inexhaustible sources such as solar and geothermal energy.
Superior DBL GV
aprox. 25m²
1 French or 2 Single Beds /Available 3rd Bed
Superior DBL Front SV
aprox. 25m²
1 French or 2 Single Bed
Superior DBL SSV
aprox. 25m²
1 French or 2 Single Beds /Available 3rd Bed
Superior TRPL SSV
aprox. 29m²
1 French or 2 Single Beds /Available 3rd Bed
Business Room Atrium
aprox. 25m²
1 French or 2 Single Beds /Available 3rd Bed
145 Superior Rooms & Suites!
Non Smoking Rooms
Rent a Car
Massage & Spa Treatments
Room service
Easy Access to the Beach
Open Pool & Pool Bar
Private VIP Pool Lounge Cafe' & Bar
Laundry Service
Parking Service (on charge)
Sunbeds & Umbrellas by the Beach
Executive Business Center
Wellness Santa Hotel's Rooms
Wellness Main Restaurant
Enjoy your everyday meals in one of Thessaloniki's best restaurants that combine luxury, coziness and an amazing view of the city during both day and night!
Wellness Santa Hotel's Chef together with a highly trained kitchen team, carefully prepare all meals using fresh ingredients along with a range of premium raw materials to ensure the best food quality and service.
The menus are based on the principles of the Greek & International cuisine, freshly cooked and presented by the Maître and his team with care and attention. There is also a wide selection of local and imported wines to accompany any meal.
The restaurant operates daily, offering a buffet or a 'la carte service and special menus.
Wellness Atrium Lounge Bar
Planning a special occasion with friends, a romantic evening for two or just looking for a meeting place? Atmospheric and elegant, the Wellness Atrium Lounge Bar is one of the most sophisticated coffee lounges.
Offering a wide variety of wines & champagnes, along with cocktails and liqueurs, it is undoubtfully the best meeting place of Thessaloniki and the perfect way to introduce luxury into your evenings.
Conferences & Events
Plan your productive and inspiring events or conferences in cooperation with our professional meeting planning staff.
Whether you're hosting a large corporate meeting or an intimate social gathering, we will provide all of the tools you need for a successful meeting.


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Mechanism of Nivolumab
Journal of pharmacy practice and education is an open access, peer reviewed journal that focuses on the interdisciplinary research offering therapeutic solutions to various neurological, genetics, psychological, and respiratory issues affecting the human beings.
Nivolumab, marketed as Opdivo, is a medication used to treat a number of types of cancer. This includes melanoma, lung cancer, renal cell carcinoma, Hodgkin lymphoma, head and neck cancer, colon cancer, and liver cancer. It is used by slow injection into a vein.
Common side effects include tiredness, rash, liver problems, muscles pains, and cough. Severe side effects may include immune-related lung, intestinal, liver, kidney, skin, or endocrine problems. Use during pregnancy may harm the baby and use when breastfeeding is not recommended. Nivolumab is a human IgG4 monoclonal antibody that blocks PD-1. It is a type of Immunotherapy and works as a checkpoint inhibitor, blocking a signal that prevents activation of T cells from attacking the cancer.
Nivolumab was approved for medical use in the United States in 2014. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. In the United Kingdom it costs the NHS about £5266 a month as of 2018. In the United States this amount costs about US$13,556 as of 2019, while in China it is about US$7,000. It is made using Chinese hamster ovary cells.
Mechanism T cells protect the body from cancer by killing certain cancer cells. But cancer cells evolve proteins to protect themselves from T cells. Nivolumab blocks those protective proteins. Thus, the T cells can kill the cancer cells. This is an example of immune checkpoint blockade.
PD-1 is a protein on the surface of activated T cells. If another molecule, called programmed cell death 1 ligand 1 or programmed cell death 1 ligand 2 (PD-L1 or PD-L2), binds to PD-1, the T cell becomes inactive. This is one way that the body regulates the immune system, to avoid an overreaction. Many cancer cells make PD-L1, which inhibits T cells from attacking the tumor. Nivolumab blocks PD-L1 from binding to PD-1, allowing the T cell to work PD-L1 is expressed on 40–50% of melanomas and has limited expression otherwise in most visceral organs with the exception of respiratory epithelium and placental tissue.
Editorial Manager
Journal of pharmacy Practice and Education


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Women's Business Enterprise National Council
This session is for aspiring or established small business owners and freelancers. The first part of class will cover:
Bring your questions for the second part of class for a group Q&A discussion.
Instructor: Patti Bisson of 585 North
When: Monday, December 9 from 6:00 - 8:00 PM
Where: CWE Vermont
431 Pine Street (Maltex Building), Suite 101
Burlington, VT 05401
Fee: $10. Must register to attend. Partial scholarships may be available to those who qualify.
Please click here to register: https://www.eventbrite.com/e/cwe-vermont-understanding-business-financials-12919-tickets-73449819387
Free Program – Cancellation and Notification Policy:
Sessions with low enrollment may be cancelled. CWE will notify you of class cancellations and changes.
If you can no longer attend a no-cost session for which you registered, please notify us at least 24 hours in advance.