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Objecting to restoration
Objecting to restoring a limited partnership to the register
A person may object to the restoration of a limited partnership by written request to the Registrar.
Information you'll need to provide
You'll need to provide us written confirmation of your objection. The objection must be lodged within the objection period stated in the public notice.
How to lodge your objection
To lodge your objection and any supporting documents, please use the 'Lodge Other General Documents' service.
- Log in to your online services account.
- On the dashboard, select the limited partnership from your 'My Businesses' list.
- From the menu, select 'Maintain Limited Partnership' and choose 'Lodge Other Documents'.
- Select 'Objection to Restoration' from the list of document types.
- Upload your objection document and click 'Submit'.
Objection to restoration received
If an objection is received to the restoration, the limited partnership cannot be restored by the Registrar. However, the applicant may consider applying to the High Court to restore the limited partnership to the register.


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CapriCMW Insurance makes it fast and convenient to pay your insurance premiums online. Choose your method of payment below and complete the secure transaction on the Moneris website.
Simply choose the method of payment to begin:
Interac Online is an electronic payment service that allows individuals and businesses to make payments directly to Capri CMW from their online banking account. In order to use Interac Online payment option, the following requirements must be met:
I am set up for online banking with one of the following financial institutions:
- Royal Bank of Canada (RBC)
- TD Canada Trust
- First Nations Bank of Canada
- Various Credit Unions including Interior Savings, Prospera Credit Union, and others
Why is my financial institution not listed?

subset: commoncrawl


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Home. Civil War fashion show in SW Pa. to revisit 1860s: EBSCOhost. Civil War Womens Clothing: Civil War Dresses, Hair Jewelry, and the Snood - Visit Gettysburg. The Civil War womens clothing outfits worn by the female citizens of Gettysburg and Victorian women visiting after the battle are hard for us to imagine in the modern age of shorts and tank tops.
There were specialized Civil War dresses every occasion: mourning gowns, ball gowns, riding habits, etc. The Hoop Skirt Civil War Southern belles are best known for their hoops. Women's Clothing of the South in the American Civil War. The clothing worn during the American Civil War (1861 - 1845) is a popular costume for Halloween and for Civil War reenactors.
In general, the fashions worn before and during the Civil War are Victorian styles, but the clothing worn by women in the Confederate States take on a slightly different consideration. Cotton was produced in the American South, but the textile mills that manufactured fabric were located in the northern states. The blockade of southern ports by northern forces prevented the importation of European as well as American fabrics.
Though blockade runners managed to move some goods through, those imports were few and far between. Fashion in the Civil War.
National History Day. National History Day in Wisconsin. Contest Rule Book.


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Once you click the Buy Now button and complete the Checkout Process, we will receive an instant notification that your $499 deposit has been made. The $499 deposit is credited towards your purchase and we cover ALL of the Closing Costs.
The remaining balance may be paid by Wire Transfer, Cashier's Check, ACH Bank Draft, Credit Card and/or Debit Card. We make the whole process super simple and we can complete your purchase in as little as 1 day.
Call or Text us anytime at 866-8-LANDiO (866-852-6346) for questions or to purchase this property.
Please reference the LANDiO Property ID Number: WY_Sweetwater_00006
This Property is SOLD
Just 450 yards off County Road 67 (Tipton-North Road) and joins BLM Land along the Northern and Eastern boundaries.
Recent photos of the actual property show Antelope and Wild Horses throughout the area.
Southern Wyoming's Carbon County is rich in wildlife. This property falls in the regions designated for hunting of Antelope, Mule Deer, Elk and Mountain Lions. For more information visit the Wyoming Game & Fish Department Website.
Nearby Points of Interest
65 miles to Rawlins, WY : Population 9,200 (more info)
77 miles to Rock Springs : Population 24,000 (more info)
Parcel Size: 80 Deeded Acres
LANDiO Property ID Number: WY_Sweetwater_00006
Account Number: R0137160
Parcel Number: 2196-17-1-00-056-00
Legal Description: T21N R96W SEC 17 N2 NE4
Access: 450 yards west of County Road 67
Property Taxes: $60 / year
Title: Free & Clear
Conveyance: Special Warranty Deed


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Data & Analytics Executive
(parttime – Groningen)
As a Data & Analytics Executive you will be involved in almost all international research projects. Your responsibility lies in programming digital surveys, testing and innovating the way surveys, fieldwork, recruiting etc. is done. Next to that, you will have to maintain the quality of the MeMoPanel (+/- 290.000 dutch respondents). What is the best way too keep the panel active? Which way do they respond best? Further you will assist with PR-research for MeMo² and MeMoPanel.
Below are the following requirements for the Data & Analytics Executive:
- You have the drive to be the best
- You are interested in marketing and advertising
- You are a real team-player
- You are interested in a practical function, with lots of changes for personal growth and input
- You have a variety of work tasks and will work in a challenging and informal working enviroment
- Bachelor/Master degree with a solid marketing knowledge and interest in market research
- You are an enterprising person with well developed analytical skills
- You are a quick learner in computer tasks (e.g. PhotoShop / HTML / Excel)
- You live nearby Groningen


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4 3rd St SW (Street Level)
Rochester, MN 55902
Telephone: (507) 226-7763
CATEGORIES: Gifts & Novelties | Summer Sale
Tessa's Office: Wine & Spirits Boutique specializes in unique, eclectic, and small batch products. Within only 184 square feet, the shop is curated to maximize your wine and spirit adventure. With 20 wine samples daily, we are sure to find your new favorite! Looking for food to go with your great wine? Our neighbors at Grand Rounds Brewing Company waive their corkage fee with wines bought from Tessa's Office.
Tessa's Office is located inside Grand Rounds Brewing Company.


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The best cheap tablets will give you the most bang for your buck with a smooth-performing operating system, which will most likely be Android or FireOS. You'll also have easy access to your favorite apps while you get to enjoy a satisfactory, portable experience.
For under $200, you can get some of the best tablets around, such as the Amazon Fire 7. It's a heavy hitter for the price, according to our Fire 7 (2019) review.
- Check out the best kids tablets
- See our Amazon Fire 7 vs. Walmart Onn face off
But of course, when you're purchasing a cheap tablet, you'll have to make some trade-offs. The question is, which features are you willing to sacrifice? We've laid out the pros and cons of the best cheap tablets we've reviewed; this way, you can get an easy-to-digest overview on which affordable tablet is the best for you.
If you want a kids-friendly tablet, consider getting the Amazon's Fire HD 8 Kids Edition, which packs a sharper screen, a protective case, free kid-friendly content and a 2-year no questions asked return policy. With a bit of trickery, you can even get Google Play on a Fire Tablet (though there are some issues involving security).
You can actually get a tablet under $200 with USB-C charging from the Amazon Fire HD 10 (2019) tablet, which also has a kids edition. We also reviewed the $64 8-inch Onn tablet, which offers pure Android, but has its own limitations.
What is the best cheap tablet?
The best cheap tablet is the Amazon Fire HD 10.
The Amazon Fire HD 10 is a tablet that can definitely hold its own in today's market. Not only does the Fire HD 10 finally charge over USB-C, but the tablet's octa-core processor makes it snappier and speedier than previous Amazon Fire tablets, which felt a little behind the curve. Add in more than 13 hours of battery life, and you've got one of the best tablets out there.
But if Amazon tablets aren't your speed, there are plenty of other best cheap tablets on this list that could better suit your needs.
The best cheap tablets you can buy today
- Amazon Fire 7
- Amazon Fire HD 10
- Amazon Fire HD 8
- Lenovo Tab 4 10
- Lenovo Tab 4 Plus, 10-inch
- Amazon Fire HD 8 Kids Edition
- Amazon Fire HD 10 Kids Edition
- Lenovo Yoga Tab 3
Our best cheap tablets list has to begin with the Fire 7, which Amazon offers at the low, low price of $50. Its price might make you think it's an unreliable device, but its sturdy-feeling case will make you think otherwise. It's also quite bright for its price. We just wish it had the Google Play store and a higher-resolution display.
See our full Amazon Fire 7 review.
The new Fire HD 10 (2019) proves that Amazon can make a fantastic tablet that's still one of the best cheap tablets, provided you pay a little more. From its fantastically long battery life to its sharp, bright display to its USB-C charging port, this slate competes with the much more expensive iPad ($329). If only it included the Google Play store or Google apps.
See our full Amazon Fire HD 10 review.
Amazon gives you more bang for less buck with the 2018 Fire HD 8 tablet; it offers 16GB of local storage, which is twice as much as 2016's model. Its 9-plus hours of battery life is OK, but the 2017 model lasted almost 2 hours longer.
See our full Amazon Fire HD 8 review.
The long-lasting Lenovo Tab 4 10 is one of the best cheap tablets you can buy with a 10-inch screen. Not only is its performance decent for its price tag, this slate lasts over 11 hours, beating the Amazon Fire HD 8. Since it comes rocking Android 7.1 Nougat, you can split its screen between two apps to make the most of its size. And that means you get the real Google Play store — enough for it to be the best cheap tablet that actually runs an unfiltered version of Android — and you can get real Google apps, like YouTube.
See our full Lenovo Tab 4 10 review.
The Lenovo Tab 4 Plus is the successor to the Lenovo Tab 4.
This 10.1-inch tablet provides an eye-catching, vivid display, features a comfortable design that is easy on your hands and has superb battery life. However, the downside is that you get an older version of Android. At the same time, the Tab 4 10 Plus is a highly rated media tablet for the price, especially since you also get a nice pair of cameras and solid speakers. No wonder it has 4 out of 5 stars on Amazon.
See our review of the full 10-inch Lenovo Tab 4 Plus.
It's not the cheapest kid-friendly Amazon tablet -- that's the Fire 7 Kids Edition-- but the $129 Fire HD 8 Kids Edition is, dollar-for-dollar, the best option available. It gives your child speedier performance and a brighter display, as well as a whole five hours of additional battery life. Sometimes it pays to spend a little more.
See our full Fire HD 8 Kids review.
If you want to get your kid something a little bigger and stay under $200, we recommend the Amazon Fire HD 10 Kids Edition. Its battery lasted an epic 13 hours and 29 minutes and it's packed with a ton of parental controls as well as a 2-year warranty, like its predecessor. Its 10-inch display is super bright, at 411 nits, and offers decent color, covering 103% of the sRGB color gamut. It's by far among the best cheap tablets for kids.
See our full Amazon Fire HD 10 Kids Edition review.
If you prioritize battery life, the Yoga Tab 3's 15 hours of life might make it the best cheap tablet for you, even though its $170 price tag is on the high-end of the budget field. The Lenovo Yoga Tab 3 may not have the most powerful processor inside, but it does make watching videos for hours easy, thanks to the built-in kickstand. The bright, 1280 x 800-pixel screen and front-facing speakers are nothing to sneeze at, either.
See our full Lenovo Yoga Tab 3 review.
How to choose the best cheap tablet for you
If you're a huge Amazon consumer, and perhaps you've got a Prime account, an Amazon tablet such as the Amazon Fire HD 10 is a perfect fit for you because you'll have easy access to all your favorite Amazon features, including Audible, Prime Video, Amazon Photos and more.
If you're not a big Amazon shopper, perhaps Amazon tablets aren't the best pick for you because you won't be utilizing many of the pre-installed apps on the tablet.
Perhaps you'll prefer having access to the Google Play store so that you can download all of your favorite Android apps and games. In that case, perhaps you'll want to opt for the 10-inch Lenovo Tab 4 Plus, which has an impressive 13 hours of battery life. You'll get all the features similar to any other Android-based phone, but on a bigger, more interactive screen.
How we test the best cheap tablets
To offer our readers a thorough and exhaustive review of the tablets that come through our labs, we dive into testing battery life, display quality, performance, audio quality and more. If there is a camera or two, we give it a whirl through real-world testing to give our readers the best description of what they can expect from our tablet review unit.
For performance, for example, we use the Geekbench benchmark to test the tablet's processing power. We also measure tablets' graphics capabilities using the 3DMark benchmark.
We sift through the tablets' software to see what pre-installed apps and programs you'll get to play around with -- or delete -- once you get the best cheap tablet for yourself.
We also compare tablets with other competitors, such as MediaPad M5 Lite vs. iPad: Why Huawei Almost Beats Apple, to give our readers a better perspective on which tablet would be the best slate for their needs.


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1. VERY FEW PEOPLE KNOW THAT I… am over 40 years old.
2. WHEN I'M NOT ON TOUR … my favourite past time is growing herbs and vegetables in the car park out the back of my warehouse.
3. WHAT I LOVE MOST ABOUT MY ART IS… working with the whole ensemble on one trick, like a giant human pyramid using 7 people.
4. A LIFE LESSON I WOULD LIKE TO SHARE WITH CENTRE COLLEGE STUDENTS IS: Follow your heart. You might not get where you want, but you will get where you need to be.
5. I DEFINE ART AS: Expression through technique.
6. MY MOST MEMORABLE MOMENT IN SHOW BUSINESS THUS FAR WAS: Rescuing a woman from a broken elevator, while I was dressed as "King Willy Wheaty" (a giant puffed wheat dressed as a king). A true super-hero moment.
7. THE PERSON WHO MOST INFLUENCED ME: Was my grandmother, who told me I could perform if I wanted too. And not to listen to people who try and tell you what you can and can't achieve.
8. IF I COULD BE ON STAGE WITH ANYONE, PAST OR PRESENT, ALIVE OR DECEASED, FICTIONAL OR REAL, IT WOULD BE: Mr Bean. Totally funny, totally inspirational, totally awesome.
9. WHILE TOURING, ONE OF MY GUILTY PLEASURES IS: Buying rare second hand books on Australian and Southeast Asian history.
More about the artist:
Jeremy "Jez" Davies has been a core member of Canberra's Warehouse Circus, co-founded circus company Kronik and has co-created many independent theatre productions. He runs Melbourne's major independent circus training space Blue Circus Studios. He has also toured puppetry to 42nd Street New York. This is his second stint with Circus Oz.
More about Circus Oz:
Get set for the breathtakingly brilliant, the beautiful, and the absurd as Australia's Circus Oz fills Newlin Hall with its renowned brand of collective physicality and mayhem. Stunt-jumping acrobats defy physics, fearless aerial artists laugh at gravity, slapstick knockabouts descend into chaos, and live onstage musicians rock the house! Founded in 1977 out of a desire to reinvent the dynamism of the traditional circus while displaying a signature Aussie voice, these acrobats, trapeze artists, jugglers, musicians, and comedians have put a fresh face on highly skilled stuntsinfused with a healthy dose of satire and sauciness for audiences across 26 countries on five continents. Each show—like every Circus Oz performance over the past 34 years—is a one-of-a-kind wonder. "With a raw, upbeat energy and lovely spirit" (Sunday Telegraph), this audacious spectacle of fun has performed on Broadway for family audiences for the past three years.
Jeremy Davies will perform with Circus Oz in Newlin Hall at Centre College's Norton Center for the Arts on Saturday and Sunday, February 15 & 16, 2013. Tickets are available on our website or by calling the box office at 1-877-HIT-SHOW.


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Imagine a gift of mooncakes that are specially crafted with rare and fine ingredients such as wild snow chrysanthemum and Tuscan spring water. The Straits Times' premium wine club, ST Wine, is collaborating with boutique gift company Empire Artisans to present a collection of Mid-Autumn wine gift sets featuring mooncakes of outstanding quality and curated fine wines.
Empire Artisans is a home-grown firm specialising in high-end lifestyle and gifting experiences, such as its exclusive applewood smoked bak kwa (barbecued meat) that comes in a gold and velvet gift box.
Its baked skin mooncakes are packaged in an elegant gold box containing four smaller gold boxes, each containing an individually sealed mooncake.
The top-of-the-range Emperor Snow Chrysanthemum Double Yolk Mooncake is infused with delicate flavours of wild snow chrysanthemum harvested from the snow-capped Kunlun Mountains in Xinjiang. The snow chrysanthemum is a much sought-after and hard-to-procure ingredient as the low-yielding flower has a short blooming season.
Empire Artisans spent three years on the research and development of its recipes and sourcing for top-rate ingredients. The aim was to make the "ultimate mooncake", a company spokesman said.
Mr Tan Ooi Boon, senior vice-president (business development) for The Straits Times, said: "We are delighted to partner Empire Artisan because they share our mission in offering the best product at the best price for our readers. Just like wine, not all mooncakes are created equally. Their secret is in the finest ingredients used, such as snow chrysanthemum, which results in an exquisite floral honey- like aftertaste for their mooncakes."
The wines featured in the gift sets are a Chilean red, the Montes Alpha Merlot 2013 rated JS 92 by James Suckling, and the Evans & Tate Breathing Space Cabernet Sauvignon 2014 rated JH 90.
The gift sets are available for order at stwine.sg
Get two bottles of wine with one box of Prince Double Yolk Imperial Lotus Paste Mooncake at $188, or two bottles of ST Wine with one box of Emperor Snow Chrysanthemum Double Yolk Mooncake at $238. Mooncake gift sets without wine are also available at $168 for two boxes of the Prince Double Yolk Imperial Lotus Paste Mooncake and $268 for two boxes of the Emperor Snow Chrysanthemum Double Yolk Mooncake. Prices are net and include delivery.
ST Wine also has special wine packages which are curated, with new wines featured monthly.
Join the ST Wine Club and enjoy surprise monthly packages of fine wines delivered to your doorstep.
•For enquiries, e-mail STWine@ sph.com.sg or call 6319-5076 during office hours.


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Women-specific organised rides: a joyful, much needed step-up for women riders, or a ride that's more intimidating than the first day at High school?
Adele sharpens her pencils and prepares to discuss…
By Adele Mitchell
While I truly believe the world would be a better place if more women rode mountain bikes, I tend to avoid organised 'women-only' rides (note – as opposed to riding with mates who are women, which is generally great). While others enthuse about the mutual support, absence of machismo and general kittens-in-a-basket loveliness of a same gender ride, my experience has led me to scuttle off in the opposite direction at the first mention of 'post-ride cupcakes'.
Just because we're all women doesn't mean we all like doing the same thing, nor have the same level of skill. Imagine if a ride was advertised as a 'men-only' ride – you'd be scratching your head about what to expect too (a detour to a shed, mid-trail press up competition, pies?).
My wariness is rooted in a women's only ride that I was asked to help lead, several years ago. It was advertised as a cross-country ride with some singletrack. On the day around thirty women turned up, all of different ability and riding everything from a High Street hardtail to a long travel full suspension bike. We also had a man join us, apparently because he didn't think his girlfriend could ride without him.
Predictably, the High Street hardtail survived for about half a mile before repeated technical issues forced the rider to return to the car park, in tears. The rest of us carried on but it wasn't long before long-travel lady decided to throw a bit of a strop every time we went up hill ('it's boring!"). She soon changed her tune when it was time to go downhill of course, and set off at speed – but not before yelling "last one down is a loser!'" at the group of obviously nervous riders behind her. Charming.
With the ride now split (it only takes one!) and 'a bit of an atmosphere' going on, those same nervous riders decided to bypass the next technical section so I took them round to the end of it to wait for the others. This proved to be quite a long wait as Ms Downhillchampionoftheworld had managed to go OTB mid trail. Anyway, she was a bit quieter after that.
But there's more to my avoidance of women's rides than the risk of being rubbed up the wrong way by someone who's a bit rude.
Truth be told I harbour a dread-filled anticipation of joining a group of women whose ability may put my riding skills to shame. Of course I should be more concerned about falling off or carrying a spare inner tube – instead my biggest fear is where I will fall in the pecking order of mountain biking sisterdom: one of the cool girls at the front (unlikely!), or the gangly one at the back doing the walk of shame down some massively technical trail while everyone else waits at the bottom, swapping high-fives and having great hair. It's like being the new girl at St Enduro's, with gap jumps in place of hockey.
This week, however, Hopetechwomen were hosting a ride on my local trails in Peaslake, and I think it's pretty awesome of them to make the effort on our behalf so I took a very deep breath, grabbed my trusty bike and joined the ride.
I turned up at the car park with a churning stomach and sweaty palms, not really knowing what level of ability to expect. After all, the days when women mostly had their other half's old bike and a flowery top are long gone. We choose our own bikes and ride them at every level. An impressive turn out of forty riders had turned up and there wasn't a High Street hardtail or a boyfriend in sight. Instead there was a sea of Commencal, Orange and Juliana bling. These women were mountain bikers from head to 5Ten-wearing feet.
Things got off to a bad start for me. Blame a severe case of 'all fingers and thumbs' but, as I went to put my back wheel on, my chain contorted into a lump of uselessness that I couldn't untangle. In the end, a nice man (I know, I know) from Hope had to help me sort my chain kerfuffle out. Which was very kind, of course, but did little to soothe my 'I'm hopeless' angst.
The ride was split into two groups – enduro rider and Hope Tech Brand Manager Rachael Walker led the easier ride group (somewhat over qualified for that role, incidentally), while ultimate mtb cool-girl Anna Glowinski had rocked up (as only cool people can) to lead the more technical ride. I've met Anna before and she is lovely – but I also know she is no stranger to defying gravity at great speed. Would I be okay pedalling along in her dusty wake?
After another deep breath I decided to leave my superego in the car park, chuck my comfort zone into the long grass, and join the vast majority of riders who were now rolling out behind Anna.
Polite conversation in the group focussed on a) do you know these trails and b) how long have you been riding for. Clearly then, I wasn't the only one who was a bit nervous. Having negotiated the first singletrack section it was clear that the average standard of riding was firmly in the 'very capable' (for either gender!) bracket. But you know what? I was doing okay, and I wasn't at the back – and not just because Anna took that position to make sure everyone got to the bottom of the trails safely.
Soon we were darting through the woods, dappled by evening sunlight, as a fast flowing train of mtb goddesses. And no one moaned about the hills. I even nailed a trail nemesis that had bugged me for months – it's amazing what you can do when faced with the potential embarrassment of holding a few strangers up.
I watched up-close as confident, ass-kicking women made scary descents look easy, and realised that my angst is nothing to do with a lack of skills. I'm already dropping my heels, sticking out my elbows and bending my knees on my lovely, capable trail bike: I just need a bit more self belief – and a lot less comfort braking.
A small group of male riders watched, jaws dropped, as forty divas of dirt and their blingy bikes rolled past them, owning the moment like a band of biking Beyonces. These women were fabulous, and I was proud to ride with them.
Afterwards we swapped tips, contact details and discussed future rides, "So many women are nervous about their ability when they turn up", Rachael tells me over a cup of tea. "But we make sure everyone has a good time".
So, what did I bring away? The knowledge that I am a better rider than I think I am, a lot of inspiration, new ride buddies… and a post-ride cupcake, which was very tasty.
For more information about Hopetechwomen rides click here.
Comments (4)
Anyone doing regular rides like this a bit further south? Trying to get my GF's confidence up again, but can't get her to come out on the MTB with me any more cos she's paranoid about holding me up sadly! Gisburn sounds wonderful, but it's a 3hr drive each way for us, which for a Tuesday night, isn't really that feasible!
mboy – Dude, it's easy; just take a nice picnic. You carry it, make time for looking at the view. Include a blanket, a couple of napkins, some chilled sauvignon (or whatever) and a couple of tumblers.
Smiles per hour, not miles per hour.
Mboy, check the Trail Takeover series of rides which happen all over the place. Last one was at Llandegla but I think they've done them at Swinley in the past.
Also Bike Park Wales are apparently going to be running more women's weekends soon.
There's a lady's ride at bedgebury on 3rd July if that's any good to you? Info on http://www.boarsonbikes.co.uk
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A Gold Coast bus driver has been caught on video scuffling with a teenager who refused to get off the vehicle.
Nine News reporter Chris O'Keefe filmed the incident with his phone after boarding the bus in Broadbeach to travel to work this morning.
The driver is seen in the video wrestling with the teenager and trying to drag him off the bus.
The 15-year-old passenger, Joran Corby, is seen grabbing the driver by the collar of his shirt.
Joran later told Nine News the scuffle began after the driver grabbed him by the throat and punched him in the face after he refused to leave.
He said the argument started over a trivial matter.
"One of my friends had a $50 note so he couldn't pay because the bus driver didn't have change," he said.
"So we all just sat up the back and the driver kept telling my friend to come and sit at the front."
The bus driver then told the teenagers to get off the bus but Joran refused.
"I said 'I've paid, I've got my ticket'," he said.
"Then he grabbed me by the throat so I stood up, then he punched me in the face."
Joran said he was "pushing the driver in the face" as the pair wrestled.
The bus company involved plans to review security footage of the incident and interview the driver before taking action.
Source: Nine News
Author: Fiona Willan
Author: Fiona Willan


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Marisol, a Venezuelan-American artist who fused Pop Art imagery and folk art in assemblages and sculptures that, together with her mysterious, Garboesque persona, made her one of the most compelling artists on the New York scene in the 1960s, died on Saturday in Manhattan. She was 85.
The cause was pneumonia, Julia M. Ruthizer, her executor, said.
María Sol Escobar, who adopted Marisol as her name when she began exhibiting in New York in the late 1950s, introduced a distinctive new element to the emerging Pop Art lexicon. Influenced equally by pre-Columbian art and the assemblages of Robert Rauschenberg, she began constructing tableaus of carved wooden figures embellished with drawings, fabric and found objects.
"The Family," exhibited at the Stable Gallery in 1962, showed a painted-wood family reminiscent of Dorothea Lange's photographs of the Dust Bowl: a seated mother holding a baby, her three children standing at her side, all staring stiffly at the viewer. They wore real shoes and sneakers. It was a down-market counterpart to her 1960 work "The Kennedy Family," which made the first family look like a set of tribal totems.
Critics were puzzled. Was Marisol a Pop artist or not? The critic Lucy Lippard, in "Pop Art" (1966), said no, calling her work "a sophisticated and theatrical folk art" that had nothing to do with Pop. It was often overtly political and funny — "clever as the very devil and catty as can be," John Canaday wrote in The New York Times of her 1967 exhibition featuring sculpture caricatures of the British royal family, President Lyndon B. Johnson and other eminent figures. She drew on celebrity images, as well, creating sculptures of John Wayne and Bob Hope.
Marisol often appeared at parties beside Andy Warhol, who turned the camera on her in his underground films "The Kiss" (1962) and "13 Most Beautiful Women" (1963). She returned the favor by creating a seated Warhol out of wooden boxes and table legs.
As Warhol did, Marisol turned self-absorption into an art form, incorporating casts of her own body parts and images of her face into works like "The Party," whose 13 figures and two servants all derived from her own features. She also fused commercial products with her work, most notably in "Love" (1962), in which a cast of her own open mouth received an upended Coca-Cola bottle.
Like Warhol and his disciple Jeff Koons, Marisol was aloof and opaque, a master of the gnomic pronouncement. "I don't think much myself," she told the critic Brian O'Doherty in The Times in 1964. "When I don't think, all sorts of things come to me."
Marisol's first show at Sidney Janis in 1966 drew the largest crowds in the history of that gallery. She was enormously popular but interviewers found her elusive, and her personal aura nearly eclipsed the art.
The "Marisol legend," Grace Glueck wrote in The New York Times Magazine in 1965, depended in no small part on "her chic, bones-and-hollows face (elegantly Spanish with a dash of Gypsy) framed by glossy black hair; her mysterious reserve and faraway, whispery voice, toneless as a sleepwalker's, but appealingly paced by a rich Spanish accent."
Seemingly indifferent to the public and the demands of an art career, Marisol periodically headed off to remote corners of the globe for years at a time, confounding her dealers.
"She was an incredibly significant sculptor who has been inappropriately written out of history," said Marina Pacini, the chief curator at the Memphis Brooks Museum of Art, where she organized a traveling survey of Marisol's work in 2014. "In the 1960s, she had more press and more visibility than Andy Warhol."
María Sol Escobar was born on May 22, 1930, in Paris, to a wealthy Venezuelan family. Her father, Gustavo, dealt in real estate. Her mother, the former Josefina Hernández, committed suicide when her daughter was 11.
She grew up in Paris and Caracas. After the family moved to Los Angeles in 1946, she attended the Westlake School for Girls and studied art with Howard Warshaw at the Jepson School. She went to Paris to study at the École des Beaux-Arts but left after a year and took courses at the Art Students League of New York, where the naïve, decorative style of Yasuo Kuniyoshi, one of her teachers, was a decisive influence. She also studied with Hans Hofmann at his schools in New York and Provincetown, Mass., but abandoned Abstract Expressionist painting for sculpture after seeing examples of pre-Columbian art at a gallery.
Leo Castelli included her in a group show with Jasper Johns and Rauschenberg in 1957 and that same year presented her first solo show. It could have been an immediate springboard into art-world fame if she had not bolted for Rome, where she lived for two years.
On her return to New York, her shows at the Stable and Sidney Janis galleries tuned her into a star. She was included in "The Art of Assemblage" in 1961 at the Museum of Modern Art, which gave her her own room in the showcase exhibition "Americans, 1963." Gloria Steinem profiled her in Glamour. In 1968 she exhibited work at both the Venice Biennale and Documenta in Kassel, West Germany.
She then went on a two-year jaunt around the world. When she returned, the art scene had changed, and she no longer fit in. She turned to more mythic, folk-oriented work, carving mahogany fishes, and explored a more private world in semi-surreal works on paper, filled with violent imagery, bearing titles like "Lick the Tire of My Bicycle" and "I Hate You Creep and Your Fetus."
In recent years, revisionist critics and curators have rediscovered her work. She was the subject of a retrospective at the Neuberger Museum of Art in Purchase, N.Y., in 2001, and her work was included in two exhibitions in 2010: "Seductive Subversion: Women Pop Artists, 1958-1968," at the Brooklyn Museum, and "Power Up: Female Pop Art," at the Kunsthalle in Vienna. Ms. Pacini's exhibition, "Marisol: Sculptures and Works on Paper," traveled to El Museo del Barrio in Manhattan.
Marisol, who leaves no immediate survivors, might or might not have cared about the renewed attention. When asked in 1964 how she would like her work to be seen by critics and the public, she seemed puzzled by the question.
"I don't care what they think," she said.


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Clinical Pilates
At Back in Strength Deakin, our approach to Clinical Pilates is quite unique.
We start with developing awareness and recruitment of specific core muscles, and progress to advanced exercises that result in a strong and stable body. We will observe you carefully to ensure you receive maximal benefit from your class and ensure your safety.
Our sessions are run in our Deakin studio and have individualised programmes and individualised attention. We use a range of equipment including; reformers, trapeze tables, wunda chairs and barrels. In addition we incorporate other Physio equipment, such as Core Align, redcord and slacklines. This allows us to make your program specific, challenging and varied.
A wonderful and enjoyable way to stay strong and active throughout your pregnancy.
Many people join a gym or buy expensive exercise equipment and begin strength training without knowing how to properly lift weights. Remember the cliché: "what you don't know can hurt you". The experienced weight lifter may be able to execute movements that may very well be dangerous for a beginner,..Read More
For an athlete, getting injured is one of the worst things that can happen. Depending on the type of injury you may be out of competition for a long time. Instead of lying on the couch throwing paper balls into a bin, speak to your physiotherapist about other forms of..Read More
The decision to return to sports after a knee replacement is one that should be made in consultation with your surgeon and physiotherapist. Your overall satisfaction with the outcome of the surgery and your pre-operative condition would have some bearing on whether you are able to return to sports or..Read More
Scar tissue and muscle adhesions can be a major cause of dysfunction in athletes and people who are very active. Swimming, bowling and computer use are some activities that eventually lead to muscle adhesions as a result of overuse. These muscle adhesions cause pain and stiffness and may also restrict..Read More
One of the major contributors of back, neck pain and general fatigue is poor posture. This throws the spine out of alignment and puts added strain on muscles. Over time this may lead to a change in the anatomical structure of the spine, and affect blood vessels, nerves and other..Read More


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Core Avionics & Industrial Announces the Acquisition of OpenGL Graphics Driver Intellectual Property for a Range of Graphics Processors for use in Safety Critical Real Time Systems
CoreAVI announces the purchase of all residual intellectual property assets of ALT Software through ALT Software's bankruptcy proceedings in Canada, where ALT Software had been headquartered. This acquisition allows for support of legacy and future graphics systems based on these technologies and expands CoreAVI's existing line of OpenGL Graphics Driver products, resulting in the broadest offering in the industry.
Airbus Defence and Space to deploy CoreAVI's DO-178C certifiable graphics solutions in their latest high performance situational awareness display products utilizing AMD embedded Radeon(tm) graphics processors
Tampa, Florida, U.S. January 5, 2015. Airbus Defence and Space has selected Core Avionics & Industrial's (CoreAVI) AMD Embedded Radeon OpenGL SC and OpenGL ES 2.0 driver suite, DO-254 GPU and DO-178C driver certification packages to be used in their latest safety certified avionics display system for situational awareness application for commercial and military aviation. The high performance graphics processing system of Airbus Defence and Space includes support for real time operating systems and safety critical operation with OpenGL graphics and complete DO-254, DO-178C and ED-12C certification artifacts.
CoreAVI enables Wind River VxWorks MILS with advanced OpenGL graphics supporting multiple independent levels of security in a multicore system architecture
On display at MILCOM 2014 (Military Communications Conference) to be held October 6-8, 2014 at the Baltimore Convention Center in Wind River's booth #643, CoreAVI, Curtiss-Wright, ANSYS, and Wind River demonstrate advanced graphics capabilities based on their fully integrated multicore, multiple secure partition solutions running on Wind River VxWorks MILS Platform.
Boeing selects CoreAVI solutions to harness the high performance capabilities of AMD embedded Radeon(tm) graphics processors to be used in next generation advanced cockpit display systems
The Boeing Company has selected the combined graphics technologies from AMD (NYSE:AMD) and Core Avionics & Industrial (CoreAVI) to enable next generation high performance avionics cockpit display systems. Boeing is the latest major avionics system manufacturer to take advantage of CoreAVI multi-platform, multi-program licensing and long term support that enables customers to maximize their investment in deploying graphics processing technologies.
CoreAVI completes delivery of its OpenGL SC driver and DO-178C certification package to Cobham Aerospace Communications
For Immediate Release: Believed to be the first ever completed DO-178C project, CoreAVI completes delivery of its OpenGL SC driver and DO-178C certification package to Cobham Aerospace.


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- Attend Events
- Stay Informed
- Learn & Teach
- Advance Your Career
- Participate & Advocate
- Connect with AAA
The below table of contents is interactive to help you navigate this page so that you are able to review the information more easily. If you would like to print these guidelines or view them as a PDF, you may review them in both standard print and large print format. This page was last updated in August 2019.
To create your poster, you will need to use software such as PowerPoint or Photoshop, other professional software programs, or open source alternatives to these programs.
After using your preferred software program to create your poster, you will need to print the poster using a professional printer service of your choice. It can be beneficial to check out multiple options to find the best price and quality for your needs. The poster material you choose to use is based on your preference. When submitting your printing order, your poster should be no larger than 4 ft high by 6 ft wide/1.2 m high by 1.8 m wide.
To travel with your poster, you will need to purchase an art or a poster tube, which may be found at a local arts & crafts store or online.
Please feel free to review the following references and resources as you prepare your poster for the Annual Meeting.


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Rob Stats
2019 SAG-AFTRA Election Candidate:
-National Secretary-Tresurer # 9
-NY Local Vice President # 9
-National Board Member NY # 46
-Local Board Member NY # 72
-Convention Delegate NY# 153
Rob Stats has over 12 years of union experience as an actor, stunt performer and stand-in.
In addition to his many years as a contributing member of SAG-AFTRA he also an educational background in Business Administration and is currently working towards his masters degree.
As a member of SAG-AFTRA he serves on the National & NY Local: Health Care & Safety Net Committees. He understands the struggle that many of our uninsured & under-insured members face on a regular basis & has been working to provide more affordable and alternative treatment options for his fellow members for the past three years.
As a performer of Hyper Exposed work I understand the importance of implementing strict safety measures & protocols to protect our members from sexual harassment & abuse in the work place.
The versatility & work ethic he bring to set as a performer is what he will bring into office to represent members of all categories in SAG-AFTRA.
He believes that all categories of membership should be represented with adequate diversity at both the national & local levels. He will make a conscience effort to not only listen to the issues that our members face, but also understand those issues and help provide adequate and timey solutions to them.
One of his many strategies at the national level in be to implement dynamic ideas to help organizing more union work in right-to-work states & create more working opportunities for current SAG-AFTRA members.
Platform Outline:
Diversity in represntation:
All of the National Officers since the 2012 Merger have been members of the Los Angeles Local. With 25 locals all across the United States, it only makes sense to have at least one National Office held by someone outside of Los Angeles. Whis is one of the biggest reasons I have chosen to run for the position of National Secretary-Treasurer.
Committee Representation at the National & Local Levels
-Diversifying committees to represent all types of performers in membership sub-categories.
-Requiring committee chairpersons to be elected officials.
-Elected officials every two years via traditional elections or
-Elected via a separate election by respective members of each category.
Hyper Exposed Work (Nudity & Close Contact/Intimate Nature) & harassment:
-Establish a formal set of suggested guidelines or stands & procedures for productions to abide by when filming any type of Hyper Exposed work.
-Mandatory need for "Intimacy Coordinators" on set any time Hyper Exposed work is being performed.
-Establish policies and procedures for enforcement of guidelines or standards & procedures.
-Have penalties and punishments that are suitable for various types of offenses and serve as deterrents to prevent multiple-time offenses.
-Have a permanent punishment for multiple-time offenders.
(Add three proposals sent to W&W to this list for more detail).
Contractual proposals that have been submitted to the negotiation for consider were as follows:
Motion 1:
-add language of "Intimacy Coordinator" to the codified agreement. And have "Intimacy Coordinators covered under SAG-AFTRA contracts in a similar manner to Stunt Coordinators. Incldued contributions towards health and pension plans.
Motion 2:
-Require a mandatory on set coordinator/advocate known as an "Intimacy Coordinator" be on set for all scenes that call for scripted work that involves hyper exposed work involving nudity, simulated sex, sexually explicit content and/or close contact work.
-All Hyper exposed work that involves nudity, sexually explicit content, nudity, simulated sex, and/or close contact shall require an "intimacy coordinator" and must be scripted and can NOT be improvised into a scene on the day of filming if an intimacy coordinator is not present at the time.
Motion 3:
-Add language to define what a "closed set" is.
This language should include but not be limited to:
Minimizing the number of individuals on set to a bare minimum for hyper exposed work involving nudity, simulated sex, sexually explicit content and/or close contact work: The bare minimum of individuals should be limited to the following: one individual operator for each camera, no more than 2 boom mic operators (no more than one if only one is needed). No dolly grip shall needed be on set if the camera is static & not moving. One wardrobe member per every two actors to collect modesty cover before the take begins and return the once the take is complete before set is re-opened to the crew. And AD's do not need to be on set to yell action & cut. No cell phones or other types of recording devices shall be permitted on a closed set.
In addition to thos motions I'd also like to see SAG-AFTRA provide members with some form of educational eminar or training for Hyper Exposed work. It can be benefictial to membrs that perform this type of work, and also members that may be interested in this type of work in the future. Proper eduction can answer a lot of questions members may have about Hyper Exposed work.
Money Management:
-Implement an education system of workshops and seminar that focus on educating on:
-Basic money management
-Affordable & Alternative investment options:
-Beneficial for tax incentives & deduction
-Investing in your career: training, equipment, facilities, etc.
-Alternative retirement options:
-Filing for unemployment
-Knowing how to file, what to file and when to file.
Constitutional Amendment:
In light of the situation pertaining to the newly negotiated Netflix contract, I will make an official motion to amend the language of the SAG-AFTRA Constitution to mandate a membership vote of approval for contracts with the magnitude of the new Netflix agreement. Too many of our members will work under this contract for it to have been approved without their vote. From base rates to residuals, allowing this contract to pass without a membership vote was criminal.
I will also push to have Netflix be incorporated into the main TV & Film contract when the time comes to renegotiate.
Pension & Health:
-Explore options to help reduce the liability value of both pension plans
-Keep track of qualifying thresholds and monitor alternate plan options for members if coverage becomes too expensive.
-Use National & Local Health-Care-Safety-Net Committees to continue to provide alternative and affordable treatment and coverage options for uninsured or under-insured members.


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Hello, my minions! The clock has struck the midnight hour and it is time for me to pontificate at you once more. Mwa ha ha ha ha!
Ahem. So I seem to recall mentioning that I was in school. I am currently attending EdCC (or Edmonds Community College, for those of you playing the home game). It shares a campus with the Lynnwood branch of Central Washington University, and as such is one of the "youngest" community colleges I've ever witnessed. What I mean by that is there is a larger percentage of fresh-out-of-high-school teens at EdCC than one might normally expect. There is even a (very) small on-campus dormitory/apartment building for the CWU kids. It's a nice enough campus - a bit spread, but not ridiculously so, with a good combination of old and new buildings. They offer a nice variety of classes, although their dance program is sadly lacking compared to other schools I've attended. They even have a pleasantly diverse online course selection. There's some absurd bureaucracy but you'll encounter that no matter where you are. All in all, I'm happy with the school.
What I find most striking about the campus, however, is the lack of personal diversity. Let me explain. This is a very ethnically/racially diverse campus - it is by far the biggest melting pot of cultures I have encountered in an institution of higher learning. I think that's fantastic. That said, they almost all seem to fit into one of three social circles - the hipsters, the fashionistas, and the "regular" kids.
The hipster population in Seattle is a little astounding to begin with. For those of you who enjoy this sort of thing, I would like to encourage you to go to Fremont some time, find a coffee shop, and play a few rounds of hipster bingo. They're everywhere - in Philosophy, I actually sit next to one of the cutest little hipsters I've ever met. She even has the iconic glasses. I'm sure in a few more years when she's old enough she'll be downing PBR and talking about how obscure all her interests are.
The fashionistas are how I refer to a certain roving sect of women I've seen on campus. They are almost exclusively Asian - this is an actual observation, so don't start calling me names - but also include a number of white girls and a handful of Muslim women who sport some of the most fantastically bedazzled hijabs I have ever seen. They are also exclusively women. While there are a number of fashionably dressed young men on campus, none of them take it to the extreme these young women do. These girls, no matter what the weather, always look like they just stepped off a runway. They huddle together for warmth in colder months, because a heavy coat would cover and wrinkle their ensemble. They slide all over the place if the parking lots ice over, because heaven forbid they trade out their ballet flats or stripper heels for something with traction. The really funny part is that they're all wearing variations of the same outfit, but the absurdity aside I have to admit that they look good. When I stop laughing as another one tries to cross the street and falls on her butt.
And then there is everyone else, and there really isn't a better way to describe it. While you will on occasion see a lone person stand out - like the strange, unkempt gentleman who wears cat ears all the time, or the rather fashionable young man with the leather trench that always seems dressed as if he's about to head off for some affair - I really haven't noticed a representation of other social groups. There are no goths, no metal heads, no kandi kids, not even any steampunks which is very surprising given the writhing life form that is the Seattle Steampunk community (more on that in a different entry). The area is very trendy/preppy/whatever you want to call it, and that is what you see at the school.
Perhaps I'm wrong, though. Perhaps it is there, and I just haven't found it yet. Perhaps I need to look harder.


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A bittersweet reminder of what could have been...
This is the Saab Aero-X Concept car, which was displayed at the Geneva International Auto Show in 2006. The Aero-X would be the last concept car under GM ownership, and the second to last concept ever from the Swedish icon.
The exterior design of this car is nothing short of elegant. The elongated hood and bulging fenders flow to the slopey fastback rear. The back end is somewhat of a breadvan design; the car featured both a hatchback trunk and a pull-out "drawer" for additional storage.
The windshield glass wraps around to the side windows with no A pillar to speak of. In true concept car fashion, there weren't any doors but rather a cockpit style canopy that lifted up and away from the body. Most certainly a nod to Saab's aeronautical history, but you probably figured that out on your own. Probably a pain to get into your car during the rain, but completely badass for a car that will never intentionally see the outdoors.
The car featured a twin-turbo 2.8l V6 engine and all-wheel-drive (sounds like a Saab, doesn't it?), good for 400hp to shoot this carbon fibre masterpiece to 60mph in under 5 seconds. Sadly, the car never saw production and Saab fizzled out from there. GM sold the company to Spyker, but they couldn't do anything with it and sold it to an electric vehicle manufacturer NEVS, and I don't think we've heard much since.
DNA Collectibles, and up and coming resin model maker, had the courage to bring this wonderful concept to the 1/18 world. I scooped one of their Aero-X's of their super limited run of 320 during an impressive Black Friday sale: 50% off!
Like most high-end resin models, this Saab has incredible details that you wouldn't find on a traditional diecast car. The photo etched badges look amazing and the pearl white paint is as glossy as a mirror. Panel gaps are phenomenal, and the headlamp lenses shine like jewels.
DNA did an amazing job with this little piece of Swedish eye candy. Proportions are fantastic, the ride height is perfect, and there's no issues with the wheel gap. Speaking of wheels, they're brilliant! Right down to the centercaps, the wheel and brake details on this thing are among the best in my collection. The whole thing is a gorgeous, gorgeous model!
Of course, the major drawback of resin models is that the cars a sealed. That means no opening canopy roof, and no sliding breadbox trunk. I know, I'm cutting onions over here too.
Another unlovable characteristic with most resin cars, the plastic film used for the windows is dangerously thin. With a canopy like the one on the Aero-X, there's a ton of real estate covered by glass. I'm afraid to handle this model; I was worried my thumb was going to pierce the roof while I positioned the car for photos.
Both of these flaws I mention are of not fault of DNA, however. This is just the nature of the resin model world.
I'm happy I got this car on sale, because it's retail price of $180 is incredibly steep. At that price, I expect perfection. The chrome foil on the front grille accent piece is a little crinkled. Lastly, the badge, exhaust outlet, and center reverse light are misaligned ever so slightly. The badge is too far right, the exhaust is too far left. I didn't know notice it until I was trying to line up the grid lines on my camera.
This is my first model from DNA, and it definitely won't be my last! They just released their 2019 lineup which includes the V70R and Coupe Concept from Volvo, as well as a Volkswagen W8 Passat. DNA is basically the model car company that we would be, if we had one...


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Motorcoach transportation, 9 nights lodging including 5 consecutive nights in the Montreal area (cost is $1079).
16 meals: 9 breakfasts and 7 dinners, local guide with you each day in Canada, guided tours of Montreal, Quebec City-Ottawa, visit Notre Dame Basilica, go to Montreal's Underground City and Ottawa's Parliament Hill, Narrated Cruise on the stunning St. Lawrence River, Admission to the world famous Montreal Tower and much more
Departure: 8:00am from Roswell Adult Center, 830 Grimes Bridge Rd. Roswell, GA,


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Feeder Protection for Primary and Secondary Distribution
Fanox SIL-A Relay has been designed for overcurrent and earth fault protection. It takes a step forward in terms of line protection providing advanced communications and more protection functions such as auto-recloser.
Moreover, the ability of being able to choose between standard /1 A or /5 A CTs easily by software, combined with more sensitive measurements, provides the flexibility and reliability you need for a complete line protection.


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So tired of squats? Every woman today wants to have a shapely and well-defined backside. The key to get rear is introducing new exercises that tone every inch of your butt.
To make your buttocks look bigger, you need to do exercises to tone and increase your muscle mass at the same time.
Alright, ready to look even sexier in those skinny jeans!
Let's begin!
1- Hip Bridge
The single-leg bridge is an excellent exercise for the buttocks that isolates each side while providing booty activation.
2- Forward Lunge
The forward lunge is one of the best body weight exercises to strengthen the body, it works the buttocks and the hamstrings. It also works the quadriceps and helps increase the range of motion of the hip flexors.
3- Bird Dog
A full-body exercise that tightens the core and strengthens the buttocks, hamstrings, quadriceps, hips, shoulders and arms
4- Plank Leg Lift
It is an isometric exercise that uses your own weight to tighten the muscles and keep them in a stationary position. It is very simple, but effective for buttocks.
5- Curtsy Squat
Curtsy squat are basic exercises if you want to work on your buttocks and legs. Also target the inner thighs and the gluteus medius, a smaller butt muscle that helps stabilize the hips for better posture.
6- Split Lunge Hop
When the leap is performed, it targets the buttocks, quadriceps, hamstrings, hip flexors, and calves. It will also activate the muscles that stabilize the core and hips, which are used for rotation movements and even improve ankle stability.
7- Pelvic Tilt
This effective exercise to tone your butt, and also helps lift and sculpt the buttocks.
8- Jump Squat
Jumping squats is one of the fastest and most effective ways to firm up your butt. The maximum, minimum and medium buttocks is the 3 big and strong muscles that form the buttocks.
Watch this video below to get a more detailed instruction guide of each exercise.
To make your glutes look bigger, it is necessary to do exercise as well as consume healthy foods. So, with this food, you can increase your buttocks and see results more quickly.


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Hot Topics in Practice Management - a Roundtable Discussion
Modern customers are more demanding than ever. Generations raised on digital and mobile technologies expect speed, choice and customization in nearly everything – including their interactions with care providers.
To succeed, veterinary practices cannot simply meet customer expectations, they must exceed them. This is forcing practice managers to completely rethink the traditional methods of contacting clients which fail to meet today's consumer expectations. Savvy practice managers are using 2-way texting and digital reminders- growing customer satisfaction and bottom line revenue.
Join this roundtable discussion to hear first-hand from veterinary team members who have embraced texting and photo sharing, intelligent reminders to her how they are better growing, serving and retaining customers while improving pet wellness compliance.
- How are consumer expectations shaping your digital strategy, including communications?
- How can you leverage 2-way texting with photo sharing across your practice team as a competitive advantage (customer acquisition, customer retention, lower costs, add new lines of revenue)?
- Who has made the jump to intelligent reminders (push notification, text, email), and what has that done for their business?


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Houston Texans vs. Tennessee Titans - 10/1/17 NFL Pick, Odds, and Prediction
Photo by USA TODAY Sports
Tennessee Titans (2-1) at Houston Texans (1-2)
NFL Football: Sunday, October 1, 2017 at 1:00 pm (NRG Stadium)
The Line: Houston Texans +1.5 -- Over/Under: 44 Click Here for the Latest Odds
TV: CBS Stream live sports and exclusive originals on ESPN+. Sign up now!
The Tennessee Titans and the Houston Texans face off in an AFC South divisional showdown in week 4 NFL action from NRG Stadium.
The Tennessee Titans will look to build on back-to-back wins, including a 33-27 victory over Seattle in week 3. Marcus Mariota threw for 225 yards and 2 touchdowns on 20 of 32 pass attempts. DeMarco Murray led the Titans with 115 yards and a touchdown on 14 carries, while Derrick Henry added 54 yards on 13 carries for Tennessee's ground attack. Rishard Matthews led the Titans' receiving corps with 6 catches for 87 yards and a touchdown, while Eric Decker and Delanie Walker each caught 4 passes and Jonnu Smith added a touchdown grab for the second straight week. Defensively, an Erik Walden sack highlighted an otherwise disappointing effort from Tennessee's D, giving up 433 yards of total offense and 27 points to a Seattle team that had scored 21 points and racked up 537 yards of total offense through the first two weeks of the season.
The Houston Texans will try to bounce back after dropping a heartbreaking 36-33 loss to New England in week 3, falling to 1-2 this season. Deshaun Watson threw for 301 yards and 2 touchdowns that were cancelled out by 2 interceptions in the loss. Lamar Miller put up 56 yards on 14 carries while Watson racked up 41 yards on 8 carries. DeAndre Hopkins led the etam with 7 catches for 76 yards, while D'Onta Freeman put up 65 yards with a pair of receptions. Ryan Griffin and Bruce Ellington each chipped in a receiving touchdown in the losing effort. The Texans combined for 5 sacks, 4 forced fumbles and a fumble recovery from Jadeveon Clowney who returned it 22 yards to the house for the defensive score.
Tennessee is 13-35-3 ATS in their last 51 division matchups and 16-37-3 ATS in their last 56 games overall while the over is 6-2 in their last 8 road games. Houston is 8-3-1 ATS in their last 12 division matchups and 1-4 ATS in their last 5 home games while the under is 10-4 in their last 14 home games. The favorite is 6-0 ATS in the last 6 meetings between these two teams.
I won't lie, I thought the Titans were just a flash in the pan until they made me eat my words last week, beating Seattle. Houston kept it close against New England and gave the Patriots a scare, but a loss like that does things to your confidence more often than not, and keeping it close in a game that has a 14-point spread is nice, but this line is low enough that Tennessee shouldn't have a problem getting the job done. Give me the Titans.
Chris's Pick Tennessee -1.5
AUTHOR: Chris Ruffolo
Follow Chris Ruffolo on Twitter @ruffthepickdawg


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On the Mac, you can pretty much count on the fact that no matter where you go, you've got a menu bar at the top of your display. Along with all the menu controls for your currently active application, you've got the all-important Apple Menu sitting there, with its System Preferences link, as well as Software Update and other old favorites. With Windows machines, the menubar is tied to the current application, and may be configured differently or behave in unexpected ways.
Back on the Mac, now that you're a big kid, you may be running a couple of different monitors. All of a sudden, the menu bar isn't behaving the same. It may appear on the primary display, but it doesn't show up on that second screen. Now when you need to invoke a menu command, you've got to navigate clear back to that other display to hit what you're after. That's where MenuPop can come in handy.
With this application, you get a menubar—or at least all the commands from your menu bar—on each display attached to your system. Specifically, you hit a hotkey and you get a pop-up menu at your mouse's current position. All the power of the menu bar, but with none of the hassle of having to navigate clear back to the other side of the world.
MenuPop is a free download. It's a Mac application, and runs under OS X version 10.6 (Snow Leopard).


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WLRH Events
Repeats every day 3 times .Friday, August 23, 2019
Saturday, August 24, 2019
Sunday, August 25, 2019
You can enjoy exquisite music at Twickenham Fest, August 23rd through 25th. The concert brings the rising stars of classical music to Alabama. In honor of its tenth anniversary, Twickenham Fest will be featuring ten concerts. There is no cost for admission, but reservations are required. For more information: http://twickenhamfest.org


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Pretty 60s vintage green abstract floral full skirt party dress is perfect for a spring or summer garden wedding.DETAILS•Nylon chiffon impressionist/abstract inspired green floral print over blush beige taffeta lining.•Fitted sleeveless bodice with scooped neck and V back neckline.•Matching fabric attached at back neckline can be tied above zipper. Really cute detail.•Slightly dropped waist with a full gathered skirt.•Layer of tulle between top and lining layer.•Back metal zipper.•Jonathan Logan label. •Made in USA/60s era.GARMENT MEASUREMENTSBust 36" Natural Waist 27"Shoulder to natural waist 15"Shoulder to dropped waist 18"Skirt length 26"FIT AND CAREYour own measurements needs to be at least an inch smaller in bust and waist to fit the dress comfortably. Gentle hand wash cool/hang to dry or dry clean.CONDITIONVery good to excellent. 3" tear on hem of tulle layer. Few spots on lining. Nothing noticeable when wearing.
Shown with petticoat for display purposes. Sold separately.
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By the end of chorus one, track one, Twisted Wheel have already rhymed "mind" with "shine". Is it any wonder that Noel and Liam handpicked them as support on their October tour? No, because the Gallaghers have always had kiss-of-death taste when it comes to patronage, and these boys are firmly destined for the also-rans pile. By recruiting this Oldham three-piece, they've merely given the world the next Proud Mary.
Filtered through The Jam, The Courteeners and The Enemy, their laboratory-perfect ladrock saw them snapped up by a major label at In The City 2007 and handed a wedge of Oasis comparisons to get them underway. They even shared a producer – in the shape of Dave Sardy, who midwifed 'Don't Believe The Truth' and 'Dig Out Your Soul'. Pity that, after flying all the way to LA to work with him, someone forgot to pack the effects pedals.
Their debut suffers heavily from a lack of variety. The guitars are all recorded meat'n'tatties clean, there's barely a noticeable riff present, and it's hard
to figure out what Sardy did before cashing his cheque, short of pressing 'Record' and 'Don't Record'. Even at
the level of amoeba-basic punk, at least the Pistols had the temerity to turn up the distortion. Arctic Monkeys' debut didn't hang around long enough to sound expansive, but they had protractor-angled riffs to burn. This
is just three-chord flailing, attached to a uniquely hackneyed line of imagery. 'Strife''s attempt to essay Manc pondlife offers us the key: "Sheila, she's a dealer/Dropped off in a blue three-wheeler".
Uh, great, but it's 2009. When did you last actually see a Reliant Robin on Britain's roads? Was it around about Christmas time? Was it on an old episode of Only Fools And Horses, perchance? They're pilfering a stock
of clichés that is at least 20 years out of date. 'Bouncing Bomb' is 'That's Entertainment' if you mistook Weller's sharply sculpted observations on the tyranny of suburbia for a simple list of blithe banalities.
'We Are Us' is the most genuinely Oasis-like cut here and it offers such bon mots as "You're you, you do what
you do", and its corollary: "I'm me, who else could I be?". We're stumped: is it a) John Selwyn Gummer? Or b)
Jonny Brown, 21-year-old lead singer of the band who are destined to usurp Liam Fray's position as ladrock's whipping boy? Twisted Wheel is an explosion of underwhelmingness, a kaleidoscope of grey, a fiesta of sag.
Gavin Haynes
More on this artist:
Twisted Wheel NME Artist Page
Twisted Wheel MySpace


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These tips help you configure your B2G interface. They help with developing, testing, troubleshooting, or if you are looking to enhance your existing interface.
The tips cover the following areas:
- Security
- High-volume transactions and performance
- Transfer all registrations
- PPSR notification retrieval (large files)
- Setting additional B2G mailbox addresses for your SPG
- Managing additional notification addresses
- Errors and charging of transactions
- Interpreting NEVDIS written-off codes
Database maintenance and scheduled outages
Database maintenance and reconciliation jobs are generally scheduled between 1 am and 7 am (AEST) every day. Transaction times may increase during this period.
The PPSR has scheduled outages to perform routine maintenance. See availability for times.


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This 1837 log house was the home of Col. Nathan Boone, son of Daniel Boone. He was a military officer and an early developer. The house retains many of its original features, such as hand-planed moldings and walnut clapboard siding. In addition to the family cemetery, there are slave graves on the property. The site features hiking trails and a picnic shelter.
Order your 2020 Official Missouri Travel Guide and start planning your #MissouriAdventure today.Order Now


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What we like to do
This service is created after a lot of inputs from a big group of extensive stock cash traders; in this service, we deliver bigger targets for Intraday trading and also we provide telephonic support on the position of the traders. In this service, we have a tendency to take utmost when making a decision on levels of calls execution and profit booking, as traders with volume should get the correct time to enter and exit the trades.
Also, the scripts during which calls are provided are voluminous. While generating a crystal cash call we first analyze broader market, then we analyze sector to which script belongs and its various sector index, then we tend to move right down to the analysis of technical patterns and after that, the level of buying and selling is generated.
Please go through our service features to get in-depth of the value proposition of Crystal Cash package:


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Time Heals All
by Rob Loveless
A fiend from the past has come for his revenge.
Some say that the past will come back to haunt you, which proves true for the citizens of the formerly peaceful town of Bellumwood. When a classmate is mysteriously murdered at a nightclub, Scott Monroe begins to do his own investigative work to find the perpetrator. After a series of various coincidences, he unveils the plans of a deranged murderer who plans to kill off several members of the student bodyincluding Scott. As the psychopath taunts police and pupils alike, Scott stumbles upon a dirty little secret kept by Bellumwood High School that occurred twenty-six years prior. With no clues left other than ominous messages and a trail of symbolic murders, he attempts to unmask the killer. Can Scott piece together the mystery before his own life is claimed in the name of revenge?
About the Author:
Rob Loveless is a Duquesne University graduate, with a bachelors degree in public relations and broadcast journalism. Originally from Mountain Top, Pennsylvania, he has been an avid reader and aspiring author from a young age. Rob currently resides in Pittsburgh and continues to write while launching his communications career.
(2016, Paperback, 234 pages)


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COSPURS: 2017/18 Episode 2
Season 2017/2018 – Episode 2
A special quick turn-around between podcasts since the Chelsea match is a big one … but, more importantly, we had to get Mac Cowie (aka "Dad") on the podcast while he was in the States!
Not only do we get some incredible stories from a long-time fan, we learn a lot about Glen, too … how he got his name, how an FA Cup semi-final loss drove him to tears, and how a 5 year-old Glen became Hoddle's favorite dance partner.
WARNING: "Colorful" language in this episode.
Questions? Comments? Like the podcast? Rate and review on iTunes so more listeners can find us!
Be sure to subscribe to the RSS feed–or look for us on iTunes–so you never miss an episode!
The Colorado Spurs Podcast is licensed under a Creative Commons Attribution 4.0 International License.
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Android | RSS


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Mass No: 3 in D Major (Op. 111), 1830
These pieces (in Noteworthy Composer format) are for private use only. You may download them for your own personal use. You may NOT market them for monetary gain. You may NOT use the scores to give a public performance unless you have the permission of the copyright holder/user who submitted the file. You will find the contact details in this file. If you are having difficulties, please contact for further advice. For more information on copyright, please read this.
hummass_dz.zip (July 2015) 60 kB
|Full name of work:
|Mass No: 3 in D Major (Op. 111), 1830
|Hummel, Johann Nepomuk (1778-1837), Austrian
|Music category:
|Classical Choral Mass
|arranged for SATB (piccolo, clarinet, French horn, bassoon) and piano (converted to strings etc)
|Name of file creator:
|Hooper, John
|e-mail address:
|john "at" learnchoralmusic "dot" co "dot" uk
|Running time:
|This ZIP File contains the following:-
1-Kyrie.nwc 1: Kyrie
2-Gloria.nwc 2: Gloria
3-Credo.nwc 3: Credo
4-Sancts.nwc 4: Sanctus
5-Bened.nwc 5: Benedictus
6-Agnus.nwc 6: Agnus Dei
There are no text/lyrics; these Files were generated purely for Choral Rehearsing purposes (using a published piano-reduction Score), and so don't look pretty even though they should sound reasonable. Voice-emphasised Midi Files of the whole work can be downloaded for free from my Website (above).
The Site also contains Midi Files for several rather more modern Composers, for which NWC versions may be available.
There is an excellent performance of (some of) this Work by Collegium Musicum 90, under Richard Hickox, starting at https://www.youtube.com/watch?v=WI983NMlTbo


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No vaccine is an island
January 2013
In the world of pharmaceuticals, vaccines have largely been islands unto themselves.
Although purely prophylactic in nature until recently, vaccine clinical trials were different than those for typical pharmaceutics, as they relied largely on surrogate endpoints in healthy individuals to determine efficacy, rather than direct endpoint improvements in unhealthy individuals. Likewise, the goal of treatment was ironically to give the patient a mild form of the disease, at least from an immunological perspective, so the body could learn to defend itself.
Recently, however, that scenario has started to change. Vaccinology is supplementing the preventative with the therapeutic. High-profile safety issues have forced researchers to look at how they present the "active" component of the vaccines and its supporting adjuvant players. The expanding market potential of the developing world has shone a brighter light on issues exclusive to these regions. Even the canonical paradigm of "one-shot-fits-all" has fallen by the wayside with an expanding variety of delivery vehiclesand yes, even a personalized approach.
To discuss some of these changes and how they have impacted one vaccine producer in particular, ddn recently spoke with Jim Tartaglia, vice president and the North American head of Sanofi Pasteur's New Vaccine unit.
ddn: We recently published two features on personalized medicinethe idea of individualizing treatment to the level of the patient based on his or her biomolecular makeup. A similar concept"vaccinomics"is developing in immunization, and would seem to fly in the face of the traditional "one-vaccine-fits-(practically)-all" paradigm.
Tartaglia: Vaccine development has traditionally been an empiric science, where you process through multiple steps to build vaccines and try to find an effective candidate. But it is also an evolving science that is relying more on convergent technologies which allow us to understand the immune system as a wholewhich may, in the long run, allow us to rely less on surrogate markers of efficacy when licensing new vaccines.
We're amassing data on a number of different fronts, both with respect to functional immune responses and protective profiles, to give us a more complete and comprehensive understanding of what's underlying a protective immune response, because you always need to relate that to the clinical outcomewhether it be protection against or modulation of infection, or some kind of therapeutic clinical outcome. I really see the systems biology approach to immune response and linking it to clinical as being something that is going to be more attainable in the short term in the more therapeutic setting.
I see immunotherapy one day being an important component of disease management in various settings. For example, the immune response is at the crux of a lot of disease states, including allergy, asthma, autoimmunity, potentially diabetes and cancer. There you have a greater opportunity to really link your immune response with a therapeutic outcome in a more manageable timeframe. I see vaccinomics as something that could be key in the therapeutic sense, in being able to dissect out what a protective outcome is and which populations are able to mount such a response.
With respect to thinking about prophylaxis and vaccinomics, a lot is being done looking at different disease states caused by infectious agents. A lot of people are trying to link these observations now from a systems biology approach to outcomes from a clinical setting and providing a better understanding of the immunobiology.
For instance, Rafick-Pierre Sécaly [of Florida's Vaccine & Gene Therapy Institute] has just published a couple of papers in this area, both with respect to dengue and tuberculosis, that could be applied to any type of clinical development for such vaccines, even as a preventive, but you won't have that validated until you actually have a vaccine. That's where you need the tight understanding of the basic biology and marrying that to clinical development and efficacy outcomes and endpoints, so you can validate the associations from the various settings that are done more upstream.
Vaccinomics and systems biology approaches are key. We are investing in these areas and trying to link them to outcomes in our clinical development efforts. It does take some planning, making sure that you can amass the right samples and assess them in the appropriate way. But you need that linkage, and it will be important in the future to better inform us and enhance our probability of success, whether it's in the prophylactic or immune therapeutic setting.
ddn: It appears that despite the availability of a hundred or more different vaccine adjuvants, most commercial vaccines seem to use only a small subset of adjuvants.
Tartaglia: Any licensed adjuvant in a vaccine formulation today is in the context of that specific formulation. There are no generic licenses from an adjuvant perspective. So, there is aluminum (whether aluminum phosphate or aluminum hydroxide), MF59 in the flu vaccine from Novartis and the GlaxoSmithKline PLC (GSK) formulation in Cervarix. There are a number of adjuvant formulations that are under development, whether they be oil-and-water emulsions, squalene or others that contain known immunomodulators, like the TLR agonists, but none of those are in-licensed products yet.
Most of the easy targets have been taken care of, and we know the tougher targets have profiles that we really feel are going to be important from an adjuvant perspective. We are going to need novel adjuvants to not just elicit the appropriate response, but also to have a durable immune response. That's especially true in prophylaxisparticularly when thinking of things that concern the developing world, where you're going to need a regimen that is cost-effective for these governments to deploy.
But novel adjuvants come with a two-edged sword. You have to remember that you're going to be using these formulations in healthy individuals, so the safety profile has to match that expectation from a risk-benefit perspective. Now, with adjuvants and immune modulators in other settings like cancer therapeutics, the risk/benefit is totally different. That being said, in all cases, one really needs to know the mechanism of action of the adjuvant, how it's actually enhancing immune responses, and have a handle on any untoward events.
Cervarix was licensed with the adjuvant ASO4, but that came with a price for GSK. They have significant post-license commitments around safety, especially from an autoimmune perspective. So you really do need to know your product; you need to know the mechanism of action. But even with that, as novel adjuvants become licensed, especially in the prophylactic setting, there's going to be significant post-license commitments looking at long-term safety in people that receive the vaccine.
Obviously, we're working on adjuvantswith our own and with othersin various areas of our new vaccine pipeline.
ddn: Sanofi Pasteur has made its mark in the control of infectious disease, but a lot of interest in recent years has shifted to the development of vaccines targeting cancer.
Tartaglia: Before I was in Pennsylvania, I headed R&D at the Toronto site for 13 years, where we had a cancer vaccine project. The program was focused on colorectal cancer and melanoma. We went to Phase II in both settings and we did not meet our endpoints, either because of enrollment sensitivities or from a clinical outcome, so we dropped the program.
I think in some ways, it was a bit premature to have such a program. I would have done it a bit different today. There are newer tools, newer ways to modulate the immune response that have come forward. Maybe we were a bit ahead of our time. The world is awaiting the GSK results with its MAGE vaccine in lung cancer, which should come out relatively soon, and we know that Provenge from Dendreon was the first cancer vaccine that was licensed in the United States.
The difficulty is you're going to need to develop your treatment in the context of standard of care, and you really need to show improvements in overall survival. You're going to have to differentiate yourself from what's out there already. You really have to demonstrate that there's true medical value to what you bring forward above what's currently used.
Not all cancers are the same within a person or between patients. Being able to better predict who will or will not respond, and being able to better modulate immune responsesboth from a positive and negative perspectivewill be key.
Maybe we didn't know enough at the time. I do believe we added to the field, but we didn't add a product to the field that can help cancer patients. I think that some of the things we did, in combination with some of the evolutions that I just mentioned, are going to be important for peoplemaybe even us some dayin developing these products such that they are a value-added component to disease management, at least of some cancers. One can think of those things even in the context beyond cancer, in areas such as autoimmunity, transplantation, diabetes, etc.
ddn: Another area of intense vaccine research is in the prevention and treatment of HIV/AIDS.
Tartaglia: I think I'm the only person still in the company who was originally involved in our efforts on HIV that started in the 1990 timeframe. I was responsible for RV144, which was the Thai efficacy study that we were involved in, published three years ago [in the New England Journal of Medicine]. This was the first vaccine regimen that was shown to be able to protect against HIV infectionalthough only at modest levelsand certainly not something that was licensable.
At that point, I put forward a strategy that would be focused on substantiating and extending upon the RV144 results, and I started discussions that led to the formation of P5 (Pox-Protein Public- Private Partnership). Since its inception, our HIV program has been partnered with academia, not-for-profit organizations, various funders (e.g., the Gates Foundation, the National Institutes of Health (NIH), the U.S. Army and the Thai Ministry of Health) and other companies (e.g., VaxGen, Merck, Novartis). The P5 is with Novartis.
One of the reasons I wanted to partner with Novartis was the RV144 results. The one-year observation suggested we had around 60-percent protection, but that protection waned with time. At the three-year post-vaccine point, we were down to 31.6 percent. I knew Novartis was involved at some level in HIV vaccine development, and we had partnered with them before. They knew how to produce the recombinant envelope component, but they also had MF59, which had a significant human safety database and was in-licensed. I thought that this would be a better adjuvant on top of the aluminum to give us a more durable response with the prime-boost regimens we were looking at.
We have an agreement with Novartis, but then became part of P5, which contains the Gates Foundation, the NIH, the HIV Vaccine Trial Network and the U.S. Army. Our focus is on extending the observations of RV144 to the Republic of South Africa, where we are looking to move to Phase IIb, which could start in the 2015 timeframe, with the appropriately designed vaccines that look to mimic, as much as possible, what we used in RV144.
So there's a development component and a research-track component, because we know that, as we speak today, although RV144 did provide some signals from a biomarker or surrogate immune perspective, those have not been fully validated. They are more hypothesis-driven. They'll form the basis of some of the questions we ask as we move forward with subsequent clinical trials.
There's a clinical research perspective, too, understanding that HIV vaccine clinical development as it exists today is an iterative process we need to build. We know that if we're able to achieve 50- to 60-percent protection in South Africa in the development track, this will lead to a license there and perhaps a deployable vaccine. Not a home run, by any means. Obviously, what we want to move towards is a globally relevant vaccine, one that's broadly protective, and we're not there yet.
We're going to have to explore new technologies, new regimens and new ways of looking at these things. In addition to having a development track, we must have a clinical research track. That way, we can bring these new elements forward and test them from a clinical perspective, but also be able to better understand them with systems biology solutions, and perhaps more firmly nail down elements around a biomarker of protection from a vaccine-induced perspective.
We are also looking to build off what we did in Thailand to potentially move to a population indication that could be licensable and deployable in Thailand. We've started some additional studies in Thailand to better understand the immune response and things around protective profiles that we talked about earlier. Hopefully, each of the elements will inform the others so that we can make decisions and move the field forward.
ddn: Sanofi Pasteur has an extensive portfolio of vaccines against well- characterized infectious diseases of the developed world, but what about emerging diseases coming from the developing world?
Tartaglia: From a business perspective, we are no. 1 in emerging markets, and facilitating vaccine R&D and deployment for the future in such areas is very important. We are at the forefront of developing a dengue vaccine. We 've just had some disappointing but promising results. We've been working on dengue for 20 years or more. It's the first vaccine in the last stage of clinical developmentPhase III clinical trials in Latin Americaso this is an important program.
The other areas that are important now in our portfolio are pneumonia caused by Strep. pneumoniae. We're working on a conserved- protein approach, and have been partnering and are looking to partner to bring that to a proof-of-concept study. We're currently in Phase I in Bangladesh in infants, and have just completed enrollment. And we have a tuberculosis vaccine program in infants and adolescents, and that is partnered with others. These are areas where one clearly needs to partner.
With infectious disease becoming more and more a global public health concern, building the clinical and regulatory infrastructures in these countries has become more important. Everything that we do in this regard goes toward that capacity building. I think that some of the things we did with HIV in Thailand, for instance, in preparing for RV144 really strengthened the Thai FDA.
If you think about the prior vaccine distribution paradigm, things were licensed first in the developed world and then 10 to 15 years later, after recouping R&D investments, people started to move to license in other parts of the world. So the national regulatory agencies in these countries were always dependent on the developed world regulators as the primary review.
Now, as we're talking about dengue, as we're talking about HIV, that 's not going to be the case, so the local regulatory agencies have to be competent in this regard. Through RV144, working with the Thai Ministry of Health, the Thai FDA and the U.S. Army, we sought to improve the strength of the Thai FDA in being able to review primary applications. I think that actually paid forward and they were able to apply these learnings to our application for Japanese encephalitis vaccine that is now licensed there.
The capacity building really helps in facilitating vaccine R&D and the ultimate implementation and deployment of programs around those vaccines.
The more we do to bolster public health in these countries bolsters the economies of these countries, and that builds stronger markets around the world for everybody. There is also the need to share risk, share investment and share the benefits to be able to effectively develop vaccines in these areas of the world, especially when thinking of our shareholders. We are in business.
The ROI is low, but that's why you have partners. You shift the equation a bit and it's more helpful. Each of the pieces has to be looked at as a whole, but whether it's in the upstream or downstream front, we're looking to public health partners (e.g.,UNICEF, GAVI). There's a push-pull mechanism, and for all the different indications, the different situations, you have different partners that you look at, and now with the Gates Foundation and the investment they have, partnering with them is also important.
When we were looking at dengue, we were looking to partner to maximize efforts to prepare for vaccination programs, so we joined forces with these international groups to raise awareness and to move dengue vaccination to a higher priority as necessary. But it also depends on the results of the study. It is similar with all of those things, whether talking about existing vaccines or ones under development.
In 2009, we acquired Shantha Biotechnics, an Indian biotech company. They've been working to develop and market several pediatric vaccines including the first recombinant Hep B vaccine that was produced in India. We're thinking about how to utilize them from an R&D perspective, but also from a manufacturing and deployment perspective in such regions.
ddn: The creation of vaccines and immunization programs for the developing world provides unique challenges that are not commonly seen with developed world immunization programs.
Tartaglia: Thermostability is a key component, and there are a number of programs that are underway here, both for existing and newly developed vaccines. Anything you can do to eliminate or reduce the reliance on cold chain and extend shelf lives so you can utilize your available doses more effectively is key. I know the Gates Foundation and other funding organizations are interested in those things. We work with these groups to look at that from a competitive and precompetitive perspective.
Depending on the device, there is also a cost-of-goods question. We were the first to license a vaccine with an intradermal device in Europe and Australia with VaxiGrip ID and then in the United States with Fluzone ID. Here, the business case is more around convenience, as opposed to effectiveness of vaccine.
ddn: Speaking of devices, there seems to have been a lot of activity in recent years focused on the delivery mechanisms for various vaccines (e.g., IM vs. ID vs. oral vs. intranasal).
Tartaglia: Some of these things are going to be more for differentiation. I don't see where what devices are available would lead to a vaccine that is more potent. Perhaps in the future, that will be the case. How you use that and where you use that will depend upon the situation at hand.
Intradermal had been used for rabies in some parts of the world, but always with the Mantoux method, which was not always reliable and needed extensive training for administrators. That's where we partnered with Becton Dickinson on the intradermal device.
Same with intranasal, where the goal was getting it to the mucosal surfaces more effectively, the areas where the viral portal of entry. One also has to look at convenience, compliance and reliability. It's not a given, but it has to be explored.
Our ability to promote and adapt to change has been essential. We're a company that has come together from three separate avenues, all three of which are about 100 years old. Innovation is key, and we 're investing a lot in innovation, both to facilitate vaccine R&D as well as deployment.
Technologies such as genomics, immunology, informatics and modeling will allow us to better appreciate the overall immune responsethe systems biologyso that we become less empiric. I don't think you can ever dismiss the empiric piece, because you're going to have to do the clinical trials, but at least it allows us to become more predictive. It's easy to say it's going to be a slam-dunk, but it's not.
We just invested in acquiring VaxDesign, a Florida-based biotech that has a system called Mimic, which is essentially a lymph node in a test tube, but with great automation behind it. One can use these in-vitro human immune systems to maybe ask different questions and get awaynot totally, but to some extentfrom the animal models that have not been predictive. This helps us gain a greater appreciation and handle on probabilities for success in our clinical development plan.
All of those elements come together around the key message of trying to use a more informed basis of progressing our development programs.
Code: E011326
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Examine the issues with changing our own views of ethics based on the situation we are in?
Management of Information Systems
Ethical and Societal Challenges for Businesses Related to Interconnected Systems
The upsurge of customer and organizational use of technology and the growing dependence on multi-device access to interconnected systems has produced numerous ethical and societal challenges for businesses.
1. Customer privacy
2. Employee privacy
3. Freedom of speech
4. Online annoyances
5. Phishing and identity theft
6. IT professionalism.
7. Predatory business practices
Choose one of the ethical and societal challenges above. Explain what the challenge is and why it is an ethical issue. Give examples of the issue. Give suggestions on how to overcome the challenge. Cite sources used in researching the issue.
The post Examine the issues with changing our own views of ethics based on the situation we are in? appeared first on nursing experts help.
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I always thought Santa Babara Polo Club is a brand of luggage bags.
Mana tau really got a real Santa Barbara Polo Club in California!
« ADV: The Jewel of NZ South Island | Main | It's Been 6 Years Since You're Gone »
I always thought Santa Babara Polo Club is a brand of luggage bags.
Mana tau really got a real Santa Barbara Polo Club in California!
not funny one
You came to California and you didn't call me?
ya lo. not funny
A picture and two line in this post only... -_-"
er... ha-ha? whats the point of this post man.
kenny posts are getting lamer and lamer..prolly he is too engrossed in commercializing his blog
Nice trip. Please blog about it when u r free
Kenny Sia's blog is getting lame. being a rolay reader of KS for years, I guess it's time to take a break fr reading his lame/ commercialized blog.
sorry kenny, you used to be funny, but..
jeff c, if you've been reading Kenny Sia's blog for years, you should've known that he writes what he wanna writes. if you wanna read funny stuff, go make your own lame jeff_cibai_kennysia.com
wenfei, go suck Kenny's dick if you like him so much. make your own lame wenfei_sucks_kenny_lanciao.com
suck his cock? why would I do that?
I like what he wrote. Sometimes it's inspiring, sometimes it's funny.
You know what pisses me off?
You're just following others. Like a dog. People said that it's lame, you follow. People are saying that they're gonna take a break, you follow. Just look at how you commented back at me.
If you're really a.. uhh, loyal reader. Use some common sense, he's still blogging though he's running his business and stuff. You know what, try doing that and see how you would end up.
Remarkable! It's really awesome piece of writing, I have got much clear idea on the topic of from this piece of writing


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FOUR ZERO is 40 days centred around the cross of Jesus Christ and how it relates to your everyday work and life.
100% of humans aged four and over spend sometime everyday doing something that can be called work. 67% of those of us between 16 and 65 years old spend more waking hours on work than anything else. So work is a massive part of our lives and effects us all, all of the time.
The most massive piece of work ever done in human history was that done by Jesus of Nazareth in six hours on the cross. It was the work, which changed the world. The heart of FOUR ZERO is to help you let this work of Jesus transform your days, so that the One who changed the world can change the way you work.
Week 6 Study Notes – Click Here
Week 5 Study Notes – Click Here
Week 4 Study Notes – Click Here
Week 3 Study Notes – Click Here
Week 2 (a) Click Here
Week 2 (b) Click Here
Week 1 (a) Click Here
Week 1 (b) Click Here
Week 1 (c) Click Here