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Python Web Development
Augurs, a pre-eminent Python Web Development Company, has 6+ years of experience in working with the latest Python web development technologies and frameworks, including Django. Our competent Python web developers choose the best framework to offer fast, secure, and reliable web solutions to the global clients. Our rich expertise in this domain has enabled us to build a variety of engaging applications: GUI applications, web development, and backend development.
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A federal judge ruled today that an Air Force major discharged in 2003 under Don't Ask, Don't Tell should be reinstated.
Judge Ronald Leighton ruled that former Maj. Margaret Witt was discharged unconstitutionally under the policy because the government hadn't shown that her firing benefited the military.Witt, a decorated reservist flight nurse, was suspended from the Air Force in 2004, after 17 years of service, and eventually discharged in October 2007.
In April 2006, during the discharge process, she sued to be reinstated, according to news reports. Leighton then dismissed her case, saying her rights had not been violated.
She appealed. In 2008, the Ninth District Court of Appeals ruled that the military can only fire a servicemember under Don't Ask, Don't Tell, if firing them will further the military's interests. The court sent the suit back to Leighton.
Today, Leighton ruled that Witt's firing was unconstitutional.
"The application of 'Don't Ask Don't Tell' to Major Margaret Witt does not significantly further the government's interest in promoting military readiness, unit morale and cohesion," he wrote in his ruling. "Her discharge from the Air Force Reserves violated her substantive due process rights under the Fifth Amendment to the United States Constitution. She should be restored to her position as a Flight Nurse with the 446th AES as soon as is practicable, subject to meeting applicable regulations touching upon qualifications necessary for continued service."
He also said that her discharge hurt her unit.
"The evidence before the Court is that Major Margaret Witt was an exemplary officer. She was an effective leader, a caring mentor, a skilled clinician, and an integral member of an effective team. Her loss within the squadron resulted in a diminution of the unit's ability to carry out its mission," Leighton wrote. "Good flight nurses are hard to find."
Leighton did not seek an injunction against the policy at large, as U.S. District Judge Virginia Philips did when she ruled DADT unconstitutional in a separate case two weeks ago. The Justice Department yesterday objected to that injunction.
Earlier this week, Senate Republicans managed to block the beginning of debate on the defense authorization bill, which funds the military, partly due to its inclusion of DADT repeal.
The military, which is undertaking a review of repeal, says it is a matter of "when," not "if."
Read the full Witt ruling:
Maj. Margaret Witt v. US Air Force
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subset: commoncrawl


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ALASKA – Kinross Gold of Toronto has decided to go forward with the Gilmore expansion at its Fort Knox gold mine about 40 km northeast of Fairbanks. The work is expected to extend the life of mine by six years to 2027 and the heap leach to 2030.
The Gilmore expansion will cost $100 million (all U.S. dollars) and recover about 1.5 million oz. of gold equivalent. The project is expected to generate an internal rate of return of 17% and net present value of $130 million based on a $1,200/oz. gold price, and an IRR of 26% and NPV of $239 million based on a $1,300/oz. gold price.
Kinross says the project includes a multi-phase layback of the existing Fort Knox pit and construction of a new leach pad. The company will use its cash flow to cover the initial capex. Construction is to begin in Q3 2018, followed by stripping in 2019, and production from Gilmore in early 2020. Ore will be stacked on the new leach pad beginning in late 2020. Milling will cease at that time.
Read the feasibility study at www.Kinross.com.


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Epcot's 19th Annual International Flower and Garden Festival Kicks Off Today
This is the second year that HGTV will sponsor the event along with the DIY Network.Read more
Park Related
This is the second year that HGTV will sponsor the event along with the DIY Network.Read more
This started more as a journal entry to keep track of where I want to go when I get toRead more
The concerts are FREE with your admission into Epcot and are performed at 5:15 pm, 6:30 pm, and 7:45 pm nightly in the American Gardens Theater in World Showcase.Read more
It takes a certain amount of bravery to ride the orange side of Mission: Space. It also would take a bit of bravery to do the same for a real authentic dining experience.Read more
We do not discriminate or poke fun (OK, yes we do) but that all depends on how much you may drink along the way, but one thing is for certain – Were going to have some serious fun!Read more
If you follow clockwise upon entering the World Showcase, chances are your staggering or seeing spots by the time you reach France, if you have sampled all the selections from each import stop above.Read more
If we used this logic in our everyday lives we wouldn't celebrate our children's first birthday. Why give them a giant cake to smash their hands into and destroy? They won't remember it right? We celebrate those moments for our own memories, not theirs. A trip to Disney World is no different.Read more
The Epcot Wine Walk is a new and fun idea that Disney came out with to introduce popular wines throughoutRead more
Disney spends a huge amount of money on Fireworks in their parks and certainly gets the attention they deserve. ForRead more
EPCOT's CANDLELIGHT PROCESSIONAL NARRATOR LINE-UP FOR 2011 The line-up is taking shape for this year. A few new narrators haveRead more
Be sure to plan accordingly for this since many of us enjoy the Food & Wine events in Epcot.Read more
Again this year, Big Bad Voodoo Daddy closes out the Epcot International Food & Wine Festival and the concert series. They are a GREAT band and not to be missed. The rest of the series isRead more


text: The guys go all Smeagol over the latest installment in a precious fantasy series, and they use the opportunity to revisit some other favorite flicks in the genre. What is best in life? Well, in addition to crushing your enemies, seeing them driven before you, and hearing the lamentation of their women, so also are the films "Conan the Barbarian", "Labyrinth", "Harry Potter", and more. Also discussed are "The Collection", "Hitchcock", and "Silver Linings Playbook". Tune in now to listen, m'lords and m'ladies!


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Simple Past vs. Past Progressive. Exercises and Tests Form See also explanations on Simple Past and Past Progressive Use After another or at the same time?
Do you want to express that the actions in the past happened one after another or at the same time? New action or already in progress? If you want to express that a new action happened in the middle of another action, you need both tenses: Simple Past the new action and Past Progressive for the action already in progress. Only mentioning or emphasising progress? Do you just want to mention that an action took place in the past (also used for short actions)? Certain Verbs The following verbs are usually only used in Simple Past (not in the progressive form). Simple Past vs. Past Progressive. Simple Past or Past Progressive - Online Exercise.
ESL Fun Grammar Games,Past Simple Vs. Past Progressive Betting TV Game. ESL Interactive Fun Games Here we have the games carefully laid out for you.
Follow the links to browse the variety of games offered. This is only the directory for interactive games and exercises. Our ESL fun games here include : Snakes and Ladders, Hangman, Spelling games, Wheel of Fortune, TV Games(Betting Game), Mazes, Memory Games, Matching exercises, Sequencing exercises, Picture Quizzes, Catch it and more. These games provide the ultimate fun in practising the following skills: Grammar Games & Interactive Exercises - Click Here!
Past Simple or Past Continuous?... Past Simple or Past Continuous?... Past continuous - Google Slides. Past progressive movie. Past Continuous and Past Simple examples in Songs! Past Simple and Past Continuous - Learn English Grammar. English Grammar in Use: Past Continuous.
Simple Past and Past Progressive 1. Past continuous/progressive tense. Play module 2 1-6 Jewel Game. Play module 2 Jewel Game. Welcome. Amazing stories. Past continuous. Garden. Past continuous. Busy. Busy. Past continuous. Nie podano tytu?u. Sports day. Arcade Game Generator. Arcade Game Generator Input one set of questions and answers, and create a whole batch of interactive, arcade-style games [view examples] Save them for use in the class, embed them in your blog/website/wiki!
IPad versions of "Wordshoot" and "Flashcards" already available - more to follow! STEP 1: QUIZ TITLE a. Type the title of your quiz in the box below. STEP 2: QUESTIONS*ANSWERS b. What is two plus two? If you would like to direct players to a particular game, specify it here: None: Free choice. Welcome.


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Source: CMA Website
The truth is, testing is the only way to determine which format works better for your particular product or service. However, you can make some assumptions by asking yourself the following questions:
- Is it a consumer or a business-to-business mailing? For B2B mailings, dimensional packages tend to get through the "gatekeeper" by looking more substantial.
- Is your product or service promotional, or does it tend to be more serious and personal? A #10 envelope tends to look more business-like. Self-mailers tend to be more promotional. However, this logic doesn't hold 100% of the time.
- Is the objective of your mailing acquisition or retention? You should be talking to your current customers differently than those prospects you're trying to acquire.
For the complete article visit: CMA Direct Mail Marketing FAQs


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When you get a rebate offer, there are certain things that are required to fulfill your obligation to receive your money back. So what does God require of us? Long before Jesus came, God directed the prophet Micah to record His requirements for us. They are not difficult; but surely will help us to have a better life.
Inspired by the Holy Spirit, the Micah records, "He has shown you, O mortal, what is good. And what does the Lord require of you? To act justly and to love mercy and to walk humbly[prudently] with your God." Micah 6:8 (NIV)
Today, act justly, love mercy (offer it freely) and walk prudently (in a way that shows care and thought for the future) with God.
Be Blessed and Be a Blessing
Remember God Loves You and I Do Too.
Mom, Granny, Sharan
Jesus is calling you – come to Him by faith.


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We support communities, organisations and networks to work together on the design of buildings, open spaces, homes and neighbourhoods.
We work openly and collaboratively across disciplines and sectors to develop research, projects, events and practical resources. We are committed to sharing the learning from our work to help affect change for people, places and practice.
Learn more about our different areas of work below.


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Taliban militants have captured a key district in Afghanistan's northern province of Kunduz, officials say.
The fighters attacked from several directions and government troops were forced to retreat to Kunduz city, which briefly fell to the Taliban last year. A lack of ammunition and reinforcements contributed to the fall of Khanabad district, the local authorities said. The Taliban have made gains since international troops officially ended their active fighting role in 2014, BBC reported.
Afghan security forces are currently battling the insurgents in nearly half of the country's 34 provinces. Earlier this week, the Taliban captured a district in neighboring Baghlan Province.
"The Taliban attacked the district from different positions and we resisted for hours but we received no support," Reuters quoted Khanabad district administrator, Hayatullah Amiri, as saying. Taliban Spokesman Zabihullah Mujahid confirmed the militants had captured the entire district, along with weapons and military vehicles, AP reported.
"If the central government does not pay attention to Kunduz, the Taliban will overrun Kunduz city as they did last year," Mohammad Yusouf Ayubi, head of the Kunduz provincial council, said.


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I bumped into one of the island's ODC (Ordinary Decent Clergy) yesterday, and the news was not good.
Like too many of his fellows, he had over-worked himself into severe illness. Unlike some he hadn't taken the management's kind offer of 'retirement on health grounds' and worked part-time (by his usual standards) until nominally well enough to put in 100 hour weeks again. To paraphrase his analogy of current 'working conditions', if clergy were butter, most Manx parishioners get dry bread.
But why should this concern any humanist/secularist/atheist, especially a hardcore one like me?
Because what he and other ODC experience is about more than the decline of established churches and organised religion. It's also about what isn't filling the gap left by retiring parish priests, who in their turn could never fill the gap left by the dismantling of the Welfare State right at the point when, entering a recession, all government departments are being told to cut back anyway.
Like it or not as atheists, full time clergy helped hold small traditional communities together and were on hand for more than just churchgoers. For example, in the case of this particular ODC I know in winter he almost weekly discovers injured pensioners forgotten by social services or neighbours. By comparison, 'hobby vicars' turn up on Sundays, do a service and go back to their other interests.
As I'm blogging regularly about the irritating stitch-up of 'community laison' between evangelicals and the Manx government, or the refurbishment of key Anglican churches with public money written off as 'heritage' or 'community and educational facilities' it is clear money (mostly from the public, not the faithful) is being thrown at the problems and so (in theory) public services exist.
In practice the public services do not exist and we can never, ever, expect that government will provide them. And the much reported 'third sector' involvement which was meant to replace them is a bigger myth than the invisible friend of the faith-led spongers reporting it.
What we actually see is the church (especially evangelicals) adopting good free market practice. They calculate which 'public service' requires little or no actual physical work and bid for it through government friends who are glad to farm it out. Politicians don't care about junkies, alkies, unconvicted prisoners or ex-convicts because that doesn't get votes. They don't care about the old, disabled or poor either because such losers have no executive directorships to offer lying toe-rags when the public doesn't re-elect them.
So, it doesn't matter to either dishonest politicians or dishonest evangelicals that proper services are provided. It only matters that caring noises are made, and that the cost to the public is apparently cut by the contracts going to faith-based amateurs with no overheads (having no qualified professionals to pay and no back-office or infrastructure costs).
Similarly, while full-time clergy acting as hospital chaplains tackle, unpaid, all the incidentals missed by the NHS (tracking down distant relatives, liasing with social services or undertakers, etc.,etc.), the vultures move in instead on the Hospice, where the desperately wealthy and their legacies are easily parted.
The broadcasting of a new film about Quentin Crisp over Christmas caused me to re-read his New York diary, Resident Alien, where I was struck by a comment on a letter Crisp received from an anonymous young gay man who complained that while there was much talk about "gay community", sadly(in Crisp's words) 'this happy confederacy does not exist'.
So, we have many lifestyle models, including Lifestyle Christianity and even Lifestyle Atheism or Humanism. But community (as in that thing where you help your neighbours and those with similar interests or problems get by) is as big a myth as the Imaginary Invisible Friend.
The difference is that we need not only to imagine it, but to make it happen.
5 years ago


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Trending News
Software Companies list in Delhi?
6 Answers
- 1 decade agoFavorite Answer
A-1 Technology Pvt Ltd Mahipalpur, Delhi a U. S. based firm, provides Offshore Software Development. Headquartered in New York, development facilities in UK, Germany, Canada, India. Here in India, two development centres, Delhi and Chandigarh with approx. team of 400 plus technocrats
2 Aaka Infotech Inc. D-670
Saraswati Vihar
Delhi 110034 Aaka Infotech Inc. is a professional web design & Development company providing full featured web services including B2B & B2C, E-commerce solutions and to act as a offshore development center for overseas development firms ASP, Call centre, Computer operator, Dot net, PHP/Mysql, Web Design, Web Developer,
3 Advance Informatics D-1070, New Friends Colony
New Delhi CAD and Engineering services firm established since last 4 years doing International Projects
Civil Engg,
4 All India Online Pvt Ltd 43, Community Centre, Naraina Industrial Area,
Phase I,
New Delhi 110028 All India On-Line Pvt. Ltd. a global e-business and Internet Commerce Company providing world-class services in India, Middle East, USA, and Mexico. We have own data centre at USA and providing local support from India
5 AMB IT INDIA LIMITED 165a, GANPATI HOUSE, GULMOHAR COMPLEX
6 Amity Pte. Limited Sumeet Chadha
New Delhi A Software Development House having offices in Singapore, USA, Australia.
7 Analyze-it Technologies K -1 / 76
Chitranjan park
New Delhi 110019 DatawareHousing, Database Administration Crm, Business Intelligence Solutions Provider Oracle, VC++, Visual Basic
8 Apostle Embedded Systems (p) Ltd. 417, Functional Industrial Estate,
New Delhi Embedded Systems, Networking and Network Security Protocol Programming/ Digital Signatures/ E-Commerce Application Programming
9 Aries Web Solutions 216, Kirti Shikhar, District Centre, Janakpuri
New Delhi 110058 Into website hosting and Designing business.
10 AsiaPacificConvergenceTechnologies -
New Delhi 110033
11 B S D Infotech jd -9B, dda flats, hari nagar
new delhi 110064 A company providing common platform to buyers and sellers accross the world.
12 BinSys Technologies Pvt. Ltd. 383, Bank Street, Munirka,
New Delhi 110067 We provide following services; 1. IT training programmes 2. IT outsourcing 3. Management Training programme
13 Brainwise Infotech Pvt. Ltd. B-138, Basement, Mohammadpur
Bhikaji Cama Place, New Delhi-66 Web Development Company
14 Broadways A-249, Defence Colony
New Delhi We are Software Consultant company doing offshore jobs and trunky projects.
15 Cache Technologies 121 Satya Niketan
New Delhi
16 CAD & SOFTWARE DESIGNERS J-4/111C, IInd Floor, DDA Flats, Kalkaji
New Delhi 110019 We are fast growing Web development organization. Having extensive experience in various areas of IT. Our clients include some of the biggest names in India and Internationally. Services: Website development, Database, ERP, CRM Applications, SEO. Computer operator
Marketing / Sales, Media / Advertising
17 Careershaper 287, Pratap House Sant Nagar, New Delhi
18 Cat Computer Services Pvt. Ltd. 2948/ A , 3rd Flr , Ranjeet Nagar
New Delhi 110008 Cat is leading provider of Anti-Virus and Internet Security tools and is leader in Anti-Virus Technology in India. A privately held company, Cat was founded in 1993 and has been actively involved in Research and Development of anti-virus software System admin-Windows,
19 CFCS C-31 Radhay Puri
Delhi 110051 Since 1993, CFCS has developed as a place for comprehensive solutions for all software, web, and services troubles. Computer Software Development and Web Solutions are the backbone of the company.
20 Confidign Solutions B-25, FIRST FLOOR,
NEW DELHI 110 020 Provides It Software Solutions Java/J2EE, Oracle,
21 Continental Computer E-294, LGF, East of Kailash
New Delhi 110065 IT Hardware and Software Maintenance Services Organization based in New Delhi ASP, Computer operator, Dot net, PHP/Mysql, Visual Basic, Web Design, Web Developer,
22 Cosmic Softech Ltd. B-1/ E-11, Mohan Co-operative Industrial Estate
Mathura Road
New Delhi 110044 A Maharishi Group IT Venture
23 Cranberry : Web Design Company Shivalik Main Road, Malviya Nagar
New Delhi 110017 Company for offshore web design and web development based in Delhi, India. ASP, Dot net, Java/J2EE, Linux, PHP/Mysql, VC++, Web Design, Web Developer,
24 D.I.Infotech Leaders Pvt.Ltd 60/ 20, Ist Floor, ashok nagar, tilak nagar
new delhi 110088 D. I. Infotech Leaders Pvt. Ltd is an software company
25 Damco Solutions Pvt. Ltd. E-46/ 8, Okhla Ind. Area Ph. II
New Delhi 110020 Damco, an IBM's Partner, provides packaged and customized software solutions with focus on E-Commerce, Client-Server Technologies and IBM AS/ 400. The Damco Competence Centers are located in New Delhi and has marketing offices in USA/ UK.
26 Dataman Computer Systems Pvt Ltd. (Corp. address)416 Bajaj House 97- Nehru Place
(H.O)25/16,Karachi Khana Kanpur-208001.
New Delhi 110019 DCSPL promoted in 1989 by group of IT professionals mainly focused on software turnkey projects process control and industrial automation projects. awarded by ISO 9001 certification. our clients include mcf trading uk ltd, Ceridian Inc. USA
27 Dataman Software CSC-8/19, Sector-8, Rohini, New Delhi-85 Dataman Softwares Offers an array of services in the field of Financial, Educational, Out bound call center, offset printing presses. We provide Database services, readymade software solution, web application design, Search engine optimization.
28 Dsi Software Pvt. Ltd. C-9/ 9532 VASANT KUNJ
NEW DELHI Most IT Skills,
29 DWON TECHNOLOGIES Near Bhikaji Cama Place
New Delhi 110066 A software and web development company, based New Delhi, INDIA. Working on Microsoft Technologies.
30 EarlySail Software Pvt Ltd Suite -6, Third Floor, Vasant Arcade
Nelson Mandela Road, Vasant Kunj
New Delhi 110070 EarlySail-an exciting US based firm providing software engineering services is a sister company of Vayusphere Inc. - a software company that was started with funding from world famous venture capital firm of Benchmark Capital and Marc Andreessen. Java / J2EE
31 Ecorel Computer Systems Pvt. Ltd. A-103, Shivalik
Malviya Nagar
New Delhi 110017 Computer Hardware Company with good turnover
32 eDynamic Softech Solutions Dynamic House, S-418, Greater kailash 2
New Delhi 110048 Software company headquartered in Canada, having representation in Europe and Australia. Our development centre is at Greater Kailash, Delhi. We have branch offices in Chennai and Okhla, Delhi.
33 Elcom Trading Company Limited 302 MADHUBAN BUILDING, 55 NEHRU PLACE
NEW DELHI 110019 Import & Resale Of Computer Integration Products Having A Turnover Of 60 Crores.
34 Elevations Consulting f/ 1, mata chowk, mahipal pur
new delhi 110037 Elevations Consulting is an Executive Search firm build with an aim to provide premium quality manpower solution by understanding clients need and to fulfill that need to IT Industries.
35 Epsilon India Pvt. Ltd. 216, A/19, FF, Gautam Nagar
Delhi 110049 Software Services
36 escosoft
New Delhi Escosoft has been promoted by the famous Escorts Ltd. , which is one of the India's top Industrial houses having an annual turnover of appox. US$ 800 million and an employee strength of over 20, 000. AS 400, Mainframe, ERP, Java/J2EE, Oracle, Oracle Financials, Telecom-Switching,
Most non-IT Skills,
37 ESRI India, NIIT GIS Ltd. 8 Balaji Estate Sudarshan Munjal Marg Kalkaji
New Delhi 110 019 A GIS focused company, ESRI India is a joint venture of NIIT with ESRI, Inc. New Delhi based ESRI India is the market leader in the Indian GIS market. At Map India 2001, ESRI India was voted as the Best GIS Solution Company of the Year.
- Anonymous4 years ago
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- Anonymous6 years ago
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Binary trading is advertised as the only genuine system that lets users earn preposterous amounts of money in ridiculously short period of time. Advertisers try to implicate as if you can make $350 every 60 seconds; if it was true then binary trading would truly be an astonishing business.
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The first challenge is finding a trustworthy binary broker; secondly, you need to find a binary trading strategy, which you can use to make profits consistently. Without an effective trading strategy, there is no way you can make money in this business.
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- How do you think about the answers? You can sign in to vote the answer.
- vakayil kLv 71 decade ago
Please check the following link for list of software companies in Delhi.
- 6 years ago
the best trading software http://tradingsolution.info
i have attended a lot of seminars, read counless books on forex trading and it all cost me thousands of dollars. the worst thing was i blew up my first account. after that i opened another account and the same thing happened again. i started to wonder why i couldn,t make any money in forex trading. at first i thought i knew everything about trading. finally i found that the main problem i have was i did not have the right mental in trading. as we know that psychology has great impact on our trading result. apart from psychology issue, there is another problem that we have to address. they are money management, market analysis, and entry/exit rules. to me money management is important in trading. i opened another account and start to trade profitably after i learnt from my past mistake. i don't trade emotionally anymore.
if you are serious about trading you need to address your weakness and try to fix it. no forex guru can make you Professional trader unless you want to learn from your mistake.


text:
- Study stopped early after review of safety and efficacy data demonstrated clear proof-of-concept and opportunity for further dose reduction to optimize clinical safety and efficacy
- Large statistically significant decreases seen for ALP in patients receiving MBX-8025; reversible dose related liver enzyme elevations observed
NEWARK, Calif., May 31, 2016 (GLOBE NEWSWIRE) -- CymaBay Therapeutics, Inc. (NASDAQ:CBAY), a clinical-stage biopharmaceutical company developing therapies to treat metabolic diseases with high unmet medical need, today announced that it has discontinued its current Phase 2 study of MBX-8025 in patients with Primary Biliary Cholangitis (PBC) after determining that the study met its objective of establishing proof-of-concept for MBX-8025 by showing marked improvements in biochemical markers of cholestasis. The study also identified a treatment emergent signal of transaminase elevations. Subsequent studies will investigate lower doses to optimize risk benefit. MBX-8025 is an orally administered potent and selective peroxisome proliferator-activated receptor delta (PPARδ) agonist.
"We are very pleased that this study demonstrated that MBX-8025 has a potent anti-cholestatic activity that could have meaningful therapeutic benefit to patients with PBC," said Harold Van Wart, Ph.D., President and Chief Executive Officer of CymaBay Therapeutics. "Having achieved clinical proof-of-concept, we can now focus on dose optimization to maximize the benefit to risk ratio in subsequent studies."
"I am impressed by the magnitude of the ALP lowering in this patient population and by the fact that it was not accompanied by pruritus," said Keith Lindor, M.D., Dean of the College of Health Solutions, Arizona State University. "I hope that CymaBay continues to explore this agent for cholestasis using lower doses."
Study details
The study was a placebo controlled, double blind, dose ranging study of 12 weeks duration in patients who had an inadequate response to ursodiol, as characterized by a persistent elevation in ALP. The study planned to enroll approximately 75 patients who were randomized to receive placebo, 50 or 200 mg doses of MBX-8025. The goal of the study was to assess whether the improvements in biochemical markers of cholestasis observed previously for MBX-8025 in other patient populations would be observed in patients with PBC.
The primary endpoint was the percent change in alkaline phosphatase (ALP). A secondary endpoint was the responder rate for patients achieving the composite criteria of serum ALP values less than 1.67xULN with a decrease of at least 15% and normal levels of total bilirubin (TBIL). ALP values were blinded to everyone involved in the study. Additional secondary endpoints were changes in gamma glutamyl transferase (GGT), TBIL and 5'-nucleotidase, other recognized biochemical markers of cholestasis. As these markers were part of the safety surveillance, they were only blinded with respect to the dosing group. It became apparent early in the study that many patients were showing pronounced decreases in these secondary efficacy endpoints, even greater decreases than those observed in earlier clinical studies, suggesting that MBX-8025 was exhibiting a potent anti-cholestatic effect.
During the study, three cases of asymptomatic increases in transaminases were observed (two in the 200 mg and one in the 50 mg cohorts). All three were reversible on cessation of treatment and were not accompanied by elevation of TBIL. No transaminase signal was observed in prior Phase 2 studies in which over 120 patients were treated with MBX-8025 at doses between 50 and 200 mg. Since the study had already shown a clear efficacy signal, the company made the decision to discontinue the study, with the knowledge that additional studies at lower doses would be needed.
After the study was unblinded, changes in the primary endpoint ALP were analyzed using data available for the 26 subjects enrolled in the study and completing at least two weeks of treatment. According to the original statistical plan, changes in ALP were calculated using the last observation carried forward (LOCF). While additional data may become available as patients complete ongoing study termination visits, this is not expected to affect the results appreciably.
The mean decreases from baseline in ALP for the 50 and 200 mg dose groups were 57% and 62%, respectively, vs. 0.37% for placebo (p < 0.0001 for both). The responder rates for the placebo, 50 and 200 mg groups were 10%, 67% and 100%, respectively. The p-values comparing the responder rates for the 50 and 200 mg groups vs. placebo were 0.020 and 0.0004 (Fisher's Exact Test), respectively. Thus, MBX-8025 exhibits a rapid and potent anti-cholestatic effect in patients with PBC. The lack of a dose response suggests that lower doses could be effective as well.
|Summary of Treatment Effects on Alkaline Phosphatase
|Treatment Group
Responder Rate‡
|MBX-8025 (50 mg)
|MBX-8025 (200 mg)
*p < .05 **p < .001 ***p < .0001 vs. placebo
‡ Percent of patients responding according to composite criteria of (1) final ALP < 1.67xULN (2) change in ALP > 15% and (3) total bilirubin < ULN
Patients receiving study drug also demonstrated improvements in metabolic parameters, including reductions of LDL-C of 16 and 26% for the 50 and 200 mg dose groups, respectively, vs. 0.8% for placebo after two weeks of dosing. It is also noteworthy that, despite the potent anti-cholestatic effect, no adverse events of pruritus were reported on treatment.
A recently completed preclinical study with MBX-8025 show that the main route of elimination of the drug is through bile and that the drug is concentrated in bile. Since patients with PBC have impaired bile flow, we believe that the exposure of the drug to the liver in patients with PBC could have been higher than in prior clinical studies in subjects with normal liver function, explaining both the more potent anti-cholestatic effect and the transaminase signal.
Conference Call
CymaBay will host a conference call today, May 31, 2016, at 8:00 a.m. ET / 5:00 a.m. PT to discuss the top line results of this Phase 2 study. The call can be accessed by dialing 1-855-327-6837 (domestic) and 1-631-891-4304 (international) five minutes prior to the start of the call. A slide presentation to be used in connection with the call entitled "MBX-8025 Phase 2 Study in Primary Biliary Cholangitis (PBC)" has been posted on CymaBay's website and can be accessed at http://ir.cymabay.com/presentations. A live audio webcast of the call can be accessed under the Investors section of CymaBay's website at http://ir.cymabay.com/events and will be available for 14 days following the call.
About MBX-8025
MBX-8025 is a potent and selective agonist of PPARδ, a nuclear receptor important for lipid transport, storage and metabolism in liver and muscle. MBX-8025 has shown favorable effects on lipid and metabolic parameters in a Phase 2 study in patients with mixed dyslipidemia. Treatment effects observed include lowering of LDL-C with selective depletion of pro-atherogenic dense LDL-C particles, decreases in triglycerides and increases in HDL-C, as well as decreases in hsCRP, a biomarker of cardiovascular inflammation. CymaBay has completed a pilot Phase 2 clinical study showing that MBX-8025 lowers LDL-C in patients with homozygous familial hypercholesterolemia (HoFH). The U.S. Food and Drug Administration (FDA) has granted the Company orphan drug designation for MBX-8025 as a treatment for HoFH and Fredrickson types I and V hyperlipoproteinemia. MBX-8025 also suppresses the synthesis of bile acids as well as upregulates hepatic transporters that export bile acids from the liver. Thus, it has an anti-cholestatic activity that may be beneficial to patients with primary biliary cholangitis (PBC). A Phase 2 study demonstrating that MBX-8025 improves markers of cholestasis in patients with PBC has recently been completed.
About CymaBay
CymaBay Therapeutics, Inc. (CBAY) is a clinical-stage biopharmaceutical company developing therapies to treat metabolic diseases with high unmet medical need, including serious rare and orphan disorders. MBX-8025 is a potent, selective, orally active PPARδ agonist. A Phase 2 study of MBX-8025 in patients with mixed dyslipidemia established that it has an anti-atherogenic lipid profile. CymaBay has completed a pilot Phase 2 study of MBX-8025 in patients with homozygous familial hypercholesterolemia and a Phase 2 study in patients with primary biliary cholangitis, establishing proof-of-concept in both indications. Arhalofenate, CymaBay's other product candidate, is a potential Urate-Lowering Anti-Flare Therapy that has completed five Phase 2 studies in gout patients. Arhalofenate has been found to reduce painful flares in joints while at the same time promoting excretion of uric acid by the kidney. This dual action addresses both the signs and symptoms of gout while managing the underlying pathophysiology of hyperuricemia.
Cautionary Statements
The statements in this press release, including those statements regarding the structure and conduct of clinical trials, future performance of CymaBay's product candidates, the potential of MBX-8025 to treat homozygous familial hypercholesterolemia or primary biliary cholangitis, the potential of MBX-8025 to be therapeutically effective at doses lower than previously studied, the therapeutic and commercial potential of CymaBay's product candidates, and any of the targeted indications for the potential future development or commercialization of CymaBay's product candidates are forward looking statements that are subject to risks and uncertainties. Actual results and the timing of events regarding the further development of CymaBay's product candidates could differ materially from those anticipated in such forward-looking statements as a result of risks and uncertainties, which include, without limitation, risks related to: the success, cost and timing of any of CymaBay's product development activities, including clinical trials of MBX-8025 and arhalofenate; effects observed in trials to date which may not be repeated in the future; any delays or inability to obtain or maintain regulatory approval of CymaBay's product candidates in the United States or worldwide; and the ability of CymaBay to obtain sufficient financing to complete development, regulatory approval and commercialization of its product candidates in the United States and worldwide. Additional risks relating to CymaBay are contained in CymaBay's filings with the Securities and Exchange Commission, including without limitation its most recent Annual Report on Form 10-K and Form 10-Q and other documents subsequently filed with or furnished to the Securities and Exchange Commission. CymaBay disclaims any obligation to update these forward-looking statements except as required by law.
For additional information about CymaBay visit www.cymabay.com.
Contacts: Sujal Shah CymaBay Therapeutics, Inc. (510) 293-8800 firstname.lastname@example.com or Hans Vitzthum LifeSci Advisors, LLC (212) 915-2568 email@example.com


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Argonne Rebels Drum and Bugle Corps
|Great Bend, Kansas
|Open Class
|Championship titles
|American Legion Nationals Champion
1971-72 in competition
1973 by proclamation
The Argonne Rebels Drum and Bugle Corps (also known as "Argonne" or "The Rebels") were an Open Class (a distinction now known as World Class) competitive junior drum and bugle corps. Based in Great Bend and Barton County, Kansas, the Rebels were one of the thirteen founding member corps of Drum Corps International.[1]
In August 1947, musician John Taff and the Rev. Joseph Tockert of the St. Rose Catholic Church started a drum and bugle corps for the Boy Scouts and Girl Scouts of the St. Rose Parish to operate under the sponsorship of the Knights of Columbus. The corps had its first public performance on November 26, 1947. When American Legion Argonne Post 180 took over the corps' sponsorship in 1949, membership was opened to all area youth, and the name was changed in recognition of the Legion Post, which had been named after the Argonne Forest, the site of major U.S. military action during World War I. In 1955, Bill and Mary Lou Fryberger became the corps directors for several years. Shortly after the Frybergers left, Glenn Opie[notes 1] became the corps director, a post he would hold through 1973. In 1974, Jenny and Bob Allford were co-directors of Argonne. H.Gene Specht became the director in 1975 and 1976. Jerry and Jan Becker became corps directors in 1977 and would continue until Argonne folded in 1988. [1][2][3]
Argonne competed with others in the Great Plains area in the 1950s and 1960s. They also competed in numerous VFW and American Legion, championships, and, in 1955, the Rebels won the first of thirteen Kansas State American Legion championships. From the mid-1950s, Argonne was also a major corps on the national scene. They were a finalist in the American Legion Nationals in 1955, '56, '61, '63,[notes 2] '65, '71, and '72; a finalist at VFW Nationals each year from 1968 through 1972; and were Legion National Champions in 1971, '72, and '73.[notes 3][1][2][3]
In 1971, two organizations were started with the intent of giving drum corps more control over their activity, which was then largely governed by the veterans organizations. The Midwest Combine was made up of the Blue Stars, Cavaliers, Madison Scouts, Santa Clara Vanguard, and the Troopers; and the United Organization of Junior Corps (also known as the "Alliance"), was formed by the 27th Lancers, Garfield Cadets, Boston Crusaders, Blessed Sacrament Golden Knights, and Blue Rock. In 1972, the ten corps from the Midwest Combine and the Alliance were joined by the Anaheim Kingsmen, the De La Salle Oaklands, and the Argonne Rebels as founding members of Drum Corps International (DCI), which remains as the sanctioning body for junior corps in North America. At the first DCI World Championships, held in Whitewater, Wisconsin on August 17 and 18, 1972, the Argonne Rebels finished in fifth place. The brass was instructed by Sandra Opie[notes 1] and was considered to be the premier brass section in drum corps; on several occasions, they received a perfect score of 5.0 for Content Analysis.[1][2]
In 1973, the expectations for Argonne were extremely high; not only had the corps finished in fifth place at DCI, but most of the members would be returning for the new season. When the expected new musical arrangements were not received from the arranger, the corps turned to Frank Minear, lead trumpeter for the Stan Kenton band, who had offered to write charts for the corps. Minear's arrangements of "Fanfare For The New" and "Málaga" were transcriptions straight from the Kenton band's arrangements. When combined with Ken Norman's arrangement of "Stars and Stripes Forever", the 1973 Argonne Rebels had what was almost unquestionably the most technically complex musical program that had ever been performed by a drum and bugle corps up to that time. Unfortunately, although things were changing under the new Drum Corps International, technical difficulty was not yet taken into consideration in judging a corps' performance. Additionally, the arrangements made getting the sounds to the fans in the stands in proper synchronization difficult at best, so that the field show was redesigned in mid-season by Drum Corps Hall of Fame senior corps designer Vince Bruni. Although Argonne would finish in eleventh place at DCI World Championships at Whitewater, the season was a disappointment for the members whose early expectations had been so high. Although future DCI Hall of Fame members Truman Crawford, Bernard Baggs, and Don Angelica addressed the corps immediately after the show and attempted to console the members, the corps would never recover from the blow.[1][2]
With the Opies' departure from the corps and Sandra Opie's move from instructor to judge, the corps' brass would never again approach its excellence of the early 1970s. In 1974, Argonne would drop to thirty-third at DCI. The corps would recover somewhat, finishing twentieth in 1975 and eighteenth in 1976, but it would fall to the lower levels of Open Class in 1977, '78, and '79 and would cease operations following the 1979 season. The Argonne Rebels would return as a Class A corps in 1983 but would leave the field for good following the 1984 season.[1][2][3] Although the Argonne Rebels have not been in field competition since 1984, its organization still exists to serve the alumni, since more than 3,000 youth from Great Bend and Barton County marched in the corps during its more than forty years of competition.[4]
During the Summer of 2015, a special exhibit remembering the Argonne Rebels was presented at the Great Bend Public Library. It was created under the auspices of the Smithsonian Institution's "Museum on Main Street" program and is sponsored by the Kansas Humanities Council. Additionally, a reunion of Argonne Rebels alumni was held on July 11, and on the 14th, the annual Drum Corps International show "Drums Across Kansas" moved from Wichita to Great Bend and renamed the "March of Champions" to honor the two-time American Legion champion corps and its alumni.[5]
Show summary (1962–84)[edit]
|Everything's Coming Up Roses (from Gypsy) Get Me To the Church on Time (from My Fair Lady) Slaughter on 10th Avenue (from On Your Toes) I Believe
|Who Will Buy (from Oliver) This Could Be the Start of Something Big Night and Day Put On A Happy Face Stars and Stripes Forever The Big Country
|Who Will Buy (from Oliver) This Could Be the Start of Something Big Stars and Stripes Forever I Could Have Danced All Night Show Me (from My Fair Lady) Get Me To the Church on Time (from My Fair Lady) Put On A Happy Face The Big Country
|Those Daring Young Men In Their Flying Machines Stars and Stripes Forever I Could Have Danced All Night Show Me (from My Fair Lady) Get Me To the Church on Time (from My Fair Lady) Who Will Buy (from Oliver) Come On In Sit Right Down The Big Country
|Those Daring Young Men In Their Flying Machines America God Bless America (from This Is the Army) Bess, You Is My Woman Now (from Porgy and Bess) Summertime (from Porgy and Bess) I Got Plenty of Nothin' (from Porgy and Bess) Our Day Will Come Jubilation T Cornpone The Big Count
|Barnum and Bailey's Favorite March American Salute Mission Impossible Hey Jude Our Day Will Come Preacher Shenandoah How the West Was Won
|Barnum and Bailey's Favorite March Mission Impossible Hey Jude Our Day Will Come Stars and Stripes Forever Shenandoah Preacher How the West Was Won
|Barnum and Bailey's Favorite March Stars and Stripes Forever Heaven on Their Minds (from Jesus Christ Superstar) I Don't Know How to Love Him (from Jesus Christ Superstar) I Only Want To Say King Herod's Song (from Jesus Christ Superstar) Crucifixcion John 19:10 (from Jesus Christ Superstar) Shenandoah
|Barnum and Bailey's Favorite March Jesus Christ Superstar Medley Stars and Stripes Forever Theme from Love Story
|Barnum and Bailey's Favorite by Karl King / Jesus Christ Superstar Medley by Andrew Lloyd Webber and Tim Rice /
Stars and Stripes Forever by John Philip Sousa / Theme (from Love Story) by Francis Lai
|Fanfare For The New by Hugo Montenegro / Malaga by Bill Holman / Stars and Stripes Forever by John Philip Sousa
|Mass by Leonard Bernstein
|French National Defile by Jean Robert Planquette, Joseph François Rauski, and Andre Turlet /
National Anthem by John Stafford Smith and Francis Scott Key. adapted by Stan Kenton /
Traces by Buddy Buie, J. R. Cobb, and Emory Gordy, Jr. / Let's Hear It For Me (from Funny Lady) by John Kander and Fred Ebb
|Channel One Suite by Bill Reddie / Fanfare For The New by Hugo Montenegro /
Farandole (from L'Arlesienne) by Georges Bizet / Flight of the Bumblebee by Nikolai Rimsky-Korsakov
|Repertoire unavailable
|New York City Rhythm by Barry Manilow and Marty Panzer / Mambo Tambo by Miguelito Valdés /
Cantina Band (from Star Wars) by John Williams / Come Sail Away by Dennis DeYoung / Stars and Stripes Forever by John Philip Sousa
|Jesus Christ Superstar by Andrew Lloyd Webber and Tim Rice / Mambo Tambo by Miguelito Valdés /
Don't Cry For Me Argentina (from Evita) by Andrew Lloyd Webber and Tim Rice / Stars and Stripes Forever by John Philip Sousa
|Corps inactive
|Alexander's Ragtime Band by Irving Berlin, Battle Hymn of the Republic by William Steffe and Julia Ward Howe, Watermelon Man by Herbie Hancock
|10th Class A
|Alexander's Ragtime Band by Irving Berlin / Battle Hymn of the Republic by William Steffe and Julia Ward Howe /
Stars and Stripes Forever by John Philip Sousa
|19th Class A
See also[edit]
- ^ a b Both corps director Glenn Opie and brass instructor Sandra Opie are in the Drum Corps International Hall of Fame.
- ^ On the way to the 1963 Legion Championships in Miami, Florida, the corps stopped for dinner in Birmingham, Alabama, several members of the corps were attacked by a group of white supremacists because some members of the corps were African-Americans. Although one member of the corps required medical care, the corps continued to Miami, where they finished in tenth place.
- ^ After the Argonne Rebels had won the American Legion title in 1971 and '72, the Legion national convention was held in Hawaii. Since few, if any, drum corps would travel to Hawaii for the Nationals, they were not held, and the Argonne Rebels were awarded the 1973 American Legion Championship by proclamation.
- ^ a b c d e f A History of Drum & Bugle Corps, Vol. 2; Steve Vickers, ed.; Drum Corps World, pub.; 2003
- ^ a b c d e "Argonne Rebels Drum And Bugle Corps, Great Bend Kansas". Archived from the original on June 3, 2011. Retrieved December 29, 2014.
- ^ a b c "History for Argonne Rebels". Retrieved December 29, 2014.
- ^ "Rural Kansas Tourism - Great Bend Exploration:". Retrieved December 29, 2014.
- ^ "Rebels with a Corps". Kansas Humanities Council. February 23, 2015. Retrieved July 8, 2017.


text:
Two world globes, one red and one blue, holding global wishes of peace, hope, goodwill and happiness, on this holiday greeting card. Your business company name will be imprinted below the message of Worlds of Good Wishes on the front of this card.
Recycled - 10% post consumer content FSC Certified Heavy weight semi gloss card stock Your name will be imprinted on the front - a proof will be emailed to you prior to production of your cards.


text:
Frankincense has been used as a natural remedy for inflammation for thousands of years. The recipes of our frankincense products are based on traditional knowledge from Buddhist monks. Organic+ Frankincense Original contains boswellic acids that inhibit the enzymes involved in inflammation and swelling of body parts. Frankincense has proven to be particularly useful for combatting chronic inflammation.
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text:
In the latest issue of SmartMoney magazine, Wall Street Journal columnist Walter Mossberg explores the relative merits of iTunes and its competitors, including Napster and Yahoo Music, in an article titled "Rent vs. Own." Essentially the article compares the Apple AA3 format with Windows Media, with a heavy focus on Windows Media's Plays for Sure subscription support.
The article has so faulty a premise (starting with its title) and so many misleading statements, that I felt compelled to challenge many of his points. The full text of the original article is here and my rebuttal to it follows:
>> In the download model championed by Apple, the music service functions like a physical record store. You choose a track, pay 99 cents, and you own it. <<
This is precisely that model that most of Apple's competitors follow as well. The fact that many of them also offer subscription services does not diminish this. Only one or two of the online music stores available through Windows Media Player require a subscription before you can buy tracks.
>> As long as you abide by the restrictions, which are designed to thwart mass copying by pirates, the song will play anywhere you want to hear it forever, with no further payments required. <<
Again, all purchased tracks from Apple's competitors are provided on this basis as well.
>> This rental model has attracted a solid audience, but it is nowhere near as popular as iTunes — not even close. That may be because the rental model is far more complicated and restrictive than iTunes, and has several big downsides. <<
This premise of "iTunes or rental" presents a false dichotomy. If people find the "rental" model too "complicated," they can choose to ignore it and consider only the purchased track model. Where is the downside in this?
>> Also, the rules for rental songs are more restrictive than for owned downloads such as Apple offers. At Yahoo, for example, you can store each song on only three computers, versus Apple's five. And you can install each song on only two portable devices, versus an unlimited number at Apple. <<
The number of PCs you can store your purchased tracks on varies by service. MusicMatch (now owned by Yahoo) and Napster allow you to store tracks on up to 3 PCs; MSN Music allows up to 5. Purchased tracks from any service can be copied an unlimited number of times to compatible portable devices.
>> At the Apple service, every song is a 99-cent download you can own, but at rental services, there are different kinds of songs. Some can be both rented and purchased (for that extra 79 cents each); others can be either rented or bought outright, but not both. Some songs can only be "streamed" — that is, they can be played directly from the Internet, but not downloaded, even on a rental basis. And some can be rented, but not streamed. You get the picture. <<
Actually, on Napster, most "rental" tracks can be downloaded, streamed, or purchased. I have come across only a few that can be "rented" and not purchased. It is true that some tracks are available for purchase only, and cannot be downloaded or streamed for free. But on iTunes, all tracks have this limitation! Does Mossberg really think that the additive option to subscribe to Napster or other services somehow diminishes their tracks-for-purchase offerings?
>> Another huge downside of the rental services is that the songs they rent — and even the ones they sell outright for the extra 79 cents — cannot be played on the world's best and most popular portable player: Apple's iPod…the rental-service songs are encoded in a format owned by Microsoft, Apple's rival, and Microsoft software is required to play them on a portable player. <<
With Apple's scheme, iTunes locks you into iPod, and vice versa. With Windows Media, an array of online stores provide tracks compatible with a wide array of players from a host of different manufacturers including Creative, iRiver, and Dell. Most Windows Media players are offered at lower costs than iPod, based on hard disk or flash memory size. The players and many of the services offer their own software, but you also give you the choice of using Windows Media Player as the single software tool for purchasing or subscription downloading or streaming of tracks, for playing them on your PC and for copying them to your portable player. The Windows Media format has created a market, while Apple has created a monopoly. Need I expand on the irony here?
>> Apple won't build the necessary Microsoft compatibility into the iPod. <<
Bingo! I wholeheartedly agree with that observation. The question is whether or not this is a defensible decision.
>> …the rental model is better for people interested in sampling a wide range of music without a large out-of-pocket expense. That might make it attractive to curious but cash-poor students, for example. The rental services also have many more "community" features than iTunes does, features that allow friends and families to share music recommendations, see what others are listening to and discuss music. So they may be better for people who view music as a social activity. <<
I'm not a cash poor student, and I'm not a teenager yearning to use my online music service as a chat or sharing tool (not that there's anything wrong with that). There's no question in my mind that music is a social activity, but my guess is that Mossberg is using the word "social" in a condescending teenage-gabbing sense of the word and does not mean to invoke the spiritual, uplifting power of music.
>> But for most people, it's no contest: Right now iTunes and the iPod are the better choice in digital music. <<
I beg to differ. Subscription services offer a great way to expand your horizons and listen to music you don't own. As you listen to the tracks you have purchased, you can click on links to artists that your service has determined have an affinity to what you're listening to. From there, you can check out the artists' discographies, pick an album, and start listening to it without plunking down more money and without having to wait for it to download. If you like what you hear, then you can buy it. I have done so many times, and have been very happy with my purchases because I knew what I was buying.
And here's a whole dimension that Apple doesn't even care to cover: owners of Windows Media Center PCs who are Napster subscribers can do all of this from their remote control, on their television (with a specially designed user interface that is living room-friendly) and listen to the music on their audio/home theater equipment. Portable players and earbuds are great (I have a Creative Zen 6GB player and I like it a lot), and music on PC speakers can be remarkably good, but getting the music on my own amplifier and speakers makes the other options sound just plain tinny. I suppose you could hook your Apple notebook up to your stereo, but it's just not going to be integrated nearly as well as a Media Center PC.
There's no question that the iPod is hugely popular and incredibly well designed, both from a technology and an industrial design perspective. Apple is heavily dominant in the portable music player market and probably will be for some time. About 25 years ago, there was another dominant player: the Sony Walkman. "Walkman" was then, as "iPod" is now, the generic noun for all products in the category. Sony had a great cash cow product that eventually became commoditized and irrelevant. Sony of course has survived, but they also had numerous other market-leading products like Betamax VCRs, Trinitron TVs, and mass market and high-end audio equipment. The Betamax died, but the PlayStation has arguably become even more important, especially as games for the console now command budgets and revenue comparable to major motion pictures.
Apple doesn't have this kind of diversified product line. In fact, iPods are starting to represent the lion's share of the company's revenue. Will the iPod eventually be "Betamaxed" or "Walkman-ed?" Will Apple become a one-trick-pony like Palm? Will it suffer a similar fate? Walter Mossberg owes his readers the courtesy of exploring these issues fairly, honestly and more thoroughly.


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USD/JPY: technical analysis 26.09.2019
Current trend
On 4-hour chart, USD/JPY is correcting down after growth to the level of 107.879. The key target of the correction is the level of 107.510, which corresponds to the middle line of Bollinger Bands. The area of 107.510 can prevent the instrument from falling as the possibility of the reverse of the price is high there. Meanwhile, breakout and pair's sustained trading below this level will let the price rich the level of 107.422 (Murray [2/8])-107.227 (Murray [1/8]). The upwward trend will be restored after the price is set above the level of 107.879. In this case, the next targets of buyers will be the level of 108.008 (Murray [5/8])-108.142. The technical picture is mixed. Bollinger Bands are pointed sideways. MACD volumes are decreasing in the negative zone. Stochastic has left the overbought area and is pointed downwards, reflecting the high possibility of the downward movement formation.
Support and resistance
Support levels: 107.617, 107.422, 107.227.
Resistance levels: 107.813, 108.008, 108.203.
Trading recommendations
Long positions can be opened above the level of 107.879 with the target at around 108.008-108.203 and stop-loss 107.779.
Short positions can be opened below the level of 107.510 with the target at around 107.422-107.227 and stop-loss 107.604.


text:
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Eighteen hot pink roses rise elegantly above dense greenery including ivy, pitta negra and salal.


text:
Wilmington – Just before 8:00 this morning, rescue crews from the Belvedere Fire Company, along with crews from the Five Points Fire Company and New Castle County Paramedics responded to Boxwood Road at Route 141 for a rollover crash.
Upon arrival, crews reported that the driver of an overturned tractor trailer had self-extricated and was uninjured.
HAZMAT and tow truck crews were requested to the scene and are currently working to right the truck.
Zone fire police and DelDOT crews have closed Boxwood Road in the area of Route 141 while crews work to clear the scene.
Delaware State Police are investigating.


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I'm baffled by the sights I'm allowed to behold in this game. You're a beauty, GW2. You're a beauty…
Innovation in Ingress
Phones are no longer just devices to call one another. Wait, that's old news? Well excuse me for trying to find at least some way to start this post. Psh, grumpy little readers. Alright, let's get to the point then: I got an Ingress invite, and I want to tell you about that. You happy now?
Anyway, Ingress. Yep, the ARG developed by Google has reached my smartphone as well, and after a dozen crashes (which are the fault of my phone), I was able to complete the tutorial and join the Enlightened (because it sounds cooler than "the Resistance" and green is awesome). So far, it looks like a nifty little game, which my phone doesn't allow me to play. Fortunately, I should be the owner of this little beauty by the end of the week, so then I will hit the town and paint it green.
It looks like a somewhat more innovative ARG so far, but I'm curious to see how it plays out. According to the Intel map, my hometown has quite some Portals which are fought over bitterly. I'm eager to join the fight!
In the mean time, I'm curious to hear about your experiences with this little game so far. Anything a freshly Enlightened like me should know? Any wisdom you have to share? Hit me up, as I prepare to bring the Shapers to this world…
How Jaime Lannister got on my good side
Before you read any further: spoiler alert. This text contains massive spoilers about the A Song of Ice and Fire books, and especially the events in A Clash of Kings and A Storm of Swords. If you still want to enjoy those books, better read something else on this blog. Please, stay on this blog. It will be worth your time.
With that out of the way, let me tell you something about Jaime Lannister. Ah, what hasn't been said about this smug-faced sisterlover already. With his good looks and his charming ways, he conquers many Westerosi hearts, but his own only beats for his twin sister. While being the father of a bunch of incest children, he still does his best to be the awesome member of the Kingsguard everybody thinks he is, despite the fact that he already killed a King he had sworn to protect. He has so much to hate, and many viewers of the HBO show and readers of the first two books really hate this arrogant tool. Until a few days ago, I was one of them.
You see, if you make it to the third book of the A Song of Ice and Fire saga, you will discover an entirely new side of Jaime. While trying to make his way to King's Landing with Brienne, the two get caught by the rather brutish and primitive Brave Companions, and in a sadistic turn of events, Jaime Lannister loses his sword-hand. That's right: this great knight loses what makes him so feared and famous, and he sure has a serious internal crisis about it. However, instead of turning into a wimpy idiot who just complains about how cruel the world is, Jaime makes up plans to get the most out of the situation, and even starts to appreciate the companionship and bravery of the female knight Brienne. When he gets a safe escort back to King's Landing without Brienne, he decides that he can't just leave her behind, rides back to Harrenhal and saves her from a bear, which she had to fight with a blunt tournament sword. Of course, he keeps his cool through all of this, almost never complaining about his lost hand, while risking his life and safety for a woman he could just as easily hate.
Ladies and gentleman, Jaime Lannister is, officially, my new favourite character of the entire saga.
Seriously, it's impressive how Jaime goes from charming jerk to handicapped good guy in just a few chapters. Even better, the entire transformation feels plausible and is well-written. It's great to see a tough, badass character like Jaime developing soft spots, and that almost makes you forget that he is the father of several incestuous children and the member of the family responsible for Eddard Stark's death (though you could write that one up to Joffrey's sheer madness). It also makes him believable, and that was just the thing he needed after being my favourite character to hate (next to Joffrey. God, I hate that brat).
So, next time you meet a fictional character that seems to be a prick, don't judge him too fast. Snape turned out okay, and Jaime Lannister seems to be a semi-good guy as well. Hate and despise them while you can, but respect them as soon as they find redemption for their douchery.
Now, if you'll excuse me, I got books to read.
Love the people, not the game
A week ago, I wrote about my return to Azeroth. Currently, my brave little panda is having some aquatic adventures, and as I kill sea monsters and gather crab meat, I wonder what called me back to World of Warcraft. Many things have changed, but the two expansions that I've skipped didn't add anything entirely new to the game. Also, there are several other MMO's out there that are just as fun (and more up-to-date) than WoW (like my beloved The Secret World). So what makes me put so much time in this old love of mine? Well, it's the people.
MMORPG's are a social experience (or at least they should be). In fact, every game is a social experience. You can't play Monopoly all by yourself, and neither can you have much fun playing football without two teams. While one half of the joy we experience during game comes from the quality of it, the other half comes from the people we play it with. The greatest MMORPG in the world could hit shelves tomorrow, but I wouldn't linger long in it if I had no one to share my excitement with.
One reason I left Azeroth behind me after the Cataclysm was because of boredom, but that boredom was born from a lack of fellow players. My guild, in which I had experienced two expansions, had started to fall apart, and we all followed our own paths. Some of us had left WoW, others were busy leveling new characters, and the rest had moved on to other guilds. The social unit that I had called "home" was no more, and so there was no guild chat in which we could tell lame jokes and no Ventrilo on which we could annoy each other with our bad taste in music. Most of these people were more than pixels to me; I knew them in real life. I knew what they looked like, and I recognised the timbre of their voices. This knowledge made their characters come to life, and thus, I travelled across Azeroth with real, organic beings, with whom I shared victory and defeat. In a way, we were a digital band of brothers.
Now, I have a new group of people who are exactly that. The people who dragged me back into a world I had almost forgotten are also the people I would have a beer or go to the movies with. Sometimes they're silly, sometimes they're childish, but they are always there with me in the game. It's a feature no game has, but that you add yourself: friends and buddies, journeying with you into new adventures.
So, be thankful for all the gaming buddies you have. Next time you rage about their low damage output or their annoying habits, be grateful for the fact that they add something to your gaming experience. Because no matter how awesome a game can be, nothing is as demotivating as a silent, lonely guild chat.
I'm the Chindividual, and I salute all gaming friends out there!
Why Dungeon World fascinates me
My winter vacation is coming to an end, and next to spending some more time with my girlfriend and playing video games, I'm also using my loads of free time to read through new tabletop role-playing games. Next to Fiasco (which I praised a few days ago), another title has caught my attention due to the amount of discussion about it in the blogosphere: Dungeon World.
If you have been so unfortunate to have not heard of this game, Dungeon World takes the well-known dungeoncrawling genre, and adds a layer of storytelling and narrative gameplay. The GM plays a rather small role in the entire campaign, being there to pose challenges to the party and to interpret their rolls. The GM himself never rolls a die (except for damage) and is only there to guide and navigate the story. This basic premise intrigued me, and now that I'm done reading the rulebook, I am more than intrigued. I am fascinated.
You see, Dungeon World puts emphasis on the conversation between players and the GM. It's an old concept, one that every one of us has used at the table: the GM describes a scene, sets the mood with the right words and when everyone has an idea of what's going on, the classic question "What do you do?" is posed. It's nothing special, but Dungeon World puts this whole conversation into the spotlights. It makes the whole back-and-forth between descriptions given by the players and the GM the essence of the game, instead of focusing on dozens of little rules that might disturb the flow of gameplay. Just keep on telling an epic story in a fascinating world full of adventures, and worry about the rules later!
Talking about a fascinating world, Dungeon World does not expect you to come up with a fleshed-out campaign setting before starting your first game. Instead, it expects you to start your first sessions with almost no preparation whatsoever, and to just use what the players throw at you. This premise is awesome: right after character creation (which also focuses on "bonds" and relationships between the party members, so that no mysterious guy has to recruit them in a pub) the players and their heroes dive into some cool scenario and fight their way out. Use what's on their sheet, instead of what's behind your screen. In a way, Dungeon World is the game for the lazy GM: just go with what your players want, as long as you keep the action flowing!
It makes me happy to see game that takes the old and somewhat boring dungeoncrawler concept, and makes it so enchanting by adding this layer of storytelling. Really, you should visit the author's homepage or head right to your digital friendly gaming store to buy it, and see what little gem they created. I will probably prod my group into playing this soon, and you will hear about it here. Have fun plundering dragon hoards!
TSWoD – More Anima, more rule hacks and more Fiddles!
Another day, another post about The Secret World of Darkness. In today's installment, we will take another look at what Anima has to offer for a character, look at some notes about conflicting rules and expand Fiddles' character sheet. Here we go!
Three reason why you should give the Song of Ice and Fire RPG a spin
A month ago, I did two things for the first time in my tabletop role-playing career. The first thing was to organise a campaign that will be played entirely online (well, except for our next session). The other thing was to start playing the Song of Ice and Fire RPG (SIFRP) by Green Ronin. I can say that both of these ideas were good ones, and I am especially surprised by the system presented in SIFRP. Today, I want to share my enthusiasm with you and give you three reasons for trying a game in Westeros.
Reason #1 – You don't create characters, you create a house
Alright, that is a lie. Sure, every player still creates a character, but before you get to that, the entire group creates a House. Anyone familiar with Martin's world knows that the Houses of Westeros play an important role in the daily life and politics, and it was a great idea to give players the chance to create their own. Through a series of dice rolls and choices, the group will give birth to a minor House, loyal to one of the famous major Houses. During their adventures, the player characters will influence the destiny of their House, and will hopefully uplift it.
The House system includes rules for the management of the House and "House Fortunes", which can be positive or negative. Players and their characters will have to decide where to take their House, and what role it will play in the Game of Thrones. It is intriguing and a nice distraction from the regular adventures and politics, and that can never be a bad thing!
Reason #2 – Combat is fast and deadly
I love Exalted. I do. I think that Exalted is one of the best games that I have ever played. But you know what I seriously hate about it? Goddamn combat. Why? Because it takes ages, and since every competent fighter is some demi-godly superhero, combat drags on and on until someone has run out of their supernatural fuel and is brutally murdered by the equivalent of a human nuclear bomb. Gosh, I hate it.
In SIFRP, combat is the exact opposite. It is fast and deadly, often done in just a few rounds. As long as a character has some competence, fights will be dramatic and exciting, yet short because of the high damage and low health points. The only problem it has is shown when two equal fighters meet each other. Then it can become the boring back-and-forth I despise so much about Exalted. However, as long as you as a GM know your PC's, and throw the right enemies in them, combat is just a delight in SIFRP.
Reason #3 – It's Westeros, damn it
Unless you have been living under a rock for the past two years, you will know that the HBO show of Martin's books has caused his fan base to grow by a gazillion percent. Everyone loves or hates Game of Thrones, but every geek on the planet now has an opinion about it.
I am not trying to say that you should play SIFRP because Westeros is all cool and mainstream now. No, what I am trying to say is that you should give the setting a spin because there is more source material now than ever before. Next to the books and source books by Green Ronin, you have two seasons of a marvelous TV show to refer to and use for your players to learn the setting. It is easier than ever before to discover the thrilling world of Westeros, and to create your own tales in it.
So, if you are still looking for a Christmas present for a fellow gamer, you could do worse than to buy him or her a copy of this game. Tell them that winter is coming, and what better to do during the Long Night than to roll some six-sided dice and pretend you are a knight?