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For a number of years the Commission has been in a position to fast track the authorisation of Qualifying Investor Funds ("QIFs") and the registration of Registered Collective Investment Schemes by placing reliance on the warranties provided by designated managers. The Commission considers that a similar approach can be taken in respect of the approval of investment compartments (i.e. sub-funds, cells and share classes) of QIFs and Registered Collective Investment Schemes. To enable the fast tracking of these approvals, the Commission has released today two new application forms being; 1) Form QIFSF and 2)Form REGSF.
The Commission can confirm that within three business days of the receipt of a fully completed Form QIFSF or Form REGSF, together with the documentation required by those forms, the Commission will issue the relevant approval.


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Abandonment and Quality Control
Even if some person or entity was able to prove first use of a trademark in the marketplace for a good or service, if other people began using the same term to describe their independent goods and services at around the same time and continued to do so for several years, any rights created by the first use would be abandoned. At some point OIF realized that any claim it might make to trademarks had been abandoned because all Osho centers and many individuals had been independently using "Osho" for at least nine years. OIF had to recreate history to try and make it appear that the centers had not, in fact, been independent during that time. Around 1998 OIF or Global Connections in Pune had sent out Letters of Understanding (LOUs) for centers to sign. Either at that...Read More

subset: commoncrawl


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WILLOUGHBY HILLS, Ohio -- The Ohio State Highway Patrol confirmed to Fox 8 News that all four victims of a Willoughby Hills plane crash were students at Case Western Reserve University.
The pilot was identified as William Michael Felten, 19, of Saginaw, Michigan.
The passengers were Lucas Vincent Marcelli, 20, of Massillon, Ohio; Abraham Pishevar, 18, of Rockville, Maryland; and John Hill, 18, of St. Simons, Georgia.
The 1999 Cessna crashed shortly after takeoff on Monday around 10 p.m. on Bishop Road just east of the Cuyahoga County Regional Airport. It was the first day of school.
People were asked to avoid Bishop Road through Tuesday afternoon.
Scott Huth, the air traffic manager at the airport, said no flight plan was filed for the plane that crashed, which is common for local flights. The pilot reported this was to be a brief, local sightseeing trip and he planned to land at the Cuyahoga County airport.
Huth also said the airport has 100-300 flights per day.
The aircraft belonged to a flying club that rents planes and trains pilots.
A National Transportation Safety Board investigator at the scene of the crash Tuesday said the pilot reported the plane was having trouble after takeoff and requested a return to the airport.
He began turning around when the plane crashed.
The investigator said Felten got his license about a year ago, but that does not indicate his experience level.
Case Western Reserve University released a statement Tuesday that said:
State police have released the names of the four young men who died in last night's plane crash. They are second-year students William Michael Felten, 20, of Saginaw, Michigan, and Lucas Marcelli, 20, of Massillon, Ohio. Also on board the plane were first-year students John Hill, 18, of St. Simons, Georgia, and Abraham Pishevar, 18, of, Rockville, Maryland.
Three of the four—Marcelli, Pishevar and Hill—were members of the university's varsity wrestling team. Felton and Marcelli also were active in Greek Life on campus.
"We are truly heartbroken about these promising lives cut short," President Barbara R. Snyder said, "and feel profound sympathy for their loved ones and friends."
Officials are still investigating the details of the crash; investigators from the National Transportation Safety Board are expected to arrive at the scene this afternoon. The plane, a 1999 Cessna, reportedly crashed just outside the Cuyahoga County about 10 o'clock Monday night. Identification of the victims was delayed because the plane caught on fire upon impact.
Counseling and student affairs staff are working closely with the undergraduates' roommates and friend to provide support and guidance. The University Counseling office is accepting walk-ins all day.
The university offered condolences at a news conference Tuesday as well.
Neighbors described what they heard and saw as the plane crashed.
"I came out and flames were shooting out pretty high. I can't tell you how high. But you could smell the fuel in the air and then all the squad cars starting coming," Mary Brenner, who lives near the crash scene, said. "It was like it instantly hit and we were out here."
"I heard the plane crash," Austin Evans, another neighbor, said. "It was just like a big boom. I live right across the street. Moments later you just smelled the jet fuel and stuff like that. It was just crazy."
Mark Gerald said he heard a sputtering sound and ran out of his house seconds after the crash.
"By the time I got maybe within twenty feet of it, that was maybe as close as I could, the flames were too intense, the heat was just very, very hot and fuselage was completely consumed," he said.
Ruzanna Tovmasyan also heard something that sounded like engine trouble.
"It was the sound of a propeller, the engine was like something was wrong. Something was wrong with the plane. You could hear it," she said.
The cause of the crash is under investigation.
Click here for extended coverage on the plane crash in Willoughby Hills.


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Charlotte Jackson is a Registered Clinical Counsellor and Clinical Supervisor working in the field of Mental Health and Substance Use for over 15 years. She works from a harm reduction, strengths based, trauma informed perspective, as well as from an anti-oppression framework.
Charlotte works with individuals and couples addressing trauma, anxiety, depression and with the integration of difficulties arising from non-ordinary states of consciousness. She is a Multidisciplinary Association for Psychedelic Studies (MAPS) trained therapist with their research study using MDMA assisted therapy for individuals with severe PTSD.
Charlotte has trained as a co-therapist with Dr. Ingrid Pacey, Principle Investigator in MAPS Phase II study researching MDMA for treatment resistant PTSD.
Charlotte has studied Holotropic Breath work with Dr. Stanislav Grof and Diane Haug.
Most recently, Charlotte has studied with Annie and Michael Mithoefer, of the Multidisciplinary Association for Psychedelic Studies (MAPS), exploring non-directive therapy as well as the non pathologizing recognition of multiplicity as manifest in MDMA assisted therapy in individuals with severe PTSD.


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96 Waioweka Road
Useful Tools
Retirement Planning
To achieve a comfortable retirement requires forward planning. You need to consider such things as when you will retire, how much income will be required to allow the retirement you desire, how to acquire that income, and what role the government will play.
The friendly team at Cookson Forbes & Associates Limited can help you answer these questions and plan for the relaxing retirement that you've earned.


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Peonies are thriving bushes in the garden, and feature bright and fragrant red, orange and pink blooms in summer. These plants are relatively hardy and do best with fall plantings in most areas, to give them time to grow and establish before the heat of summer arrives. Peonies can grow in a range of soil types, but do best in acidic to neutral soil that drains quickly. They require only minimal feedings when they sit in good soil.
Nutrition for peonies should start at planting, to ensure an easier gardening experience. These plants need quick drainage and a pH of 6.0 to 7.0, so incorporate 4 inches of organic matter into the top 12 inches of soil at planting. This matter ensures drainage, nutrition and moisture retention for the plants.
Peonies do well with 10-10-10 fertilizer, bone meal or superphosphate at planting, though gardeners must mix these amendments into soil that doesn't touch the plant roots. Avoid over fertilization or nitrogen-heavy fertilizer, as this will weaken the plant's growth.
Continued Care
Feed peonies in spring after spring growth begins. Give each plant 1/2 cup of slow-release low-nitrogen fertilizer like 5-10-10 or 10-20-20. Add 2 inches of organic compost to the soil around each peony plant in spring as well, to maintain soil health, drainage and nutrition. Use well-rotted manure as an organic alternative to synthetic fertilizer.
Mulch protects soil temperature and moisture, and restricts weed growth around peonies. As mulch breaks down, it also adds organic nutrients to the soil, to help maintain soil and plant health. Keep a 2- to 3-inch layer of mulch on the soil around peonies at all times to aid the plants in their growth.


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Tech Day 031
2013.7.20 1919 going to the corn field
2013.7.20 Cars at show
2013.7.20 Cutting wood
2013.7.20 Dodges Lined up for Rides Train in background
2013.7.20 Engine
2013.7.20 getting in place
2013.7.20 hold on
2013.7.20 Kim and Tom
2013.7.20 line-up
2013.7.20 racing 2
2013.7.20 Racing the train
2013.7.20 Tom behind the wheel
2013.7.20 tracks
2013.7.20 loading Truck
DODGE BROTHERS CLUB©,INC. Founded 1983 Incorporated 1986 For the research and preservation of Dodge Brothers Motor Vehicles and Graham Brothers Commercial Vehicles 1914-1938 DODGE BROTHERS CLUB NEWS© Dodge Brothers Club News ISSN 10600817 is published bi-monthly. Regular issues in the volume are: Dec/Jan, Feb/Mar, Apr/May, Jun/Jul, Aug/Sep, Oct/Nov.


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About the ProductSpunky and often elusive are the birds of the wild. Sold in sets of two, Kala captures their grace and tenacity in its elegant stance and plumage on your tabletop.
The BrandMore about this Brand
Kenneth Cobonpue has always gravitated towards the natural. While completing his Industrial Design degree at Pratt Institute in New York in the late 80s, he apprenticed for a leather and wood workshop near Florence Italy. He also studied furniture marketing and production in Reutlingen Germany. It wasn't until 1996 that he returned home to the Philippines to manage Interior Craft of the Islands Inc; a company founded by his mother in 1972.
Environmental Performance


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Here's a fun and sweet twist on traditional cornbread from cookbook author and baking expert Julie Hasson. Try it for breakfast, as part of your Thanksgiving lineup, or for dessert. This cornbread is not only delicious, but vegan too.
How to Make It
Make the cornbread: Preheat the oven to 400°. Grease a 10-inch cast iron skillet well with shortening.
Combine the cornmeal, flour, granulated sugar, baking powder, and salt in a large bowl. In a medium bowl, whisk together the orange juice, soymilk, and oil. Add the soymilk mixture to the flour mixture, stirring just until combined. Add the cranberries and orange zest and fold in, being careful not to overmix the batter.
Scoop the batter into the prepared skillet. Bake until lightly browned on top and a tester inserted in the center comes out clean, 40 to 50 minutes. Remove the cornbread from the oven and place on a rack to cool slightly.
Make the orange "butter": In a small bowl, whisk together the margarine, confectioners' sugar, and orange juice concentrate until smooth.
Serve the cornbread warm, spread with the "butter."
The Lodge Cast Iron Cookbook


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Code folding not working for methods with JavaDoc comments (#2114) Follow
Hi All,
Just noticed (#2114+, win XP) that code folding doesn't work for methods with JavaDoc comments. For such methods the JavaDoc is collapsed to "{...}" while before I believe this was "/*.../". And the method body doesn't have the small folding controls outlining it.
Anybody else having same problem?
2 comments
Comment actions
happens here too - WinXP, B2114
Comment actions
Yup, still in 2118. Filed a tracker entry yet?
Please sign in to leave a comment.


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Where To Find This Example
Select Help > Open Examples... from the menus and type either the example name listed above or one of the keywords below.
Or in Version 13 or higher you can open the project directly from this page using this button. Make sure to select the Enable Guided Help before clicking this button.
Design Notes
Double Stub EM Optimization Example
This example demonstrates MWO's ability to perform optimization on an EM structure. In the interest of simulation speed and simplicity, and relatively basic structure, a double stub microstrip filter, is being optimized.
Setup Details
There are two schematics in this project, "New_Discrete_Optimization" and "Old_Discrete_Optimization". The "Old_Discrete_Optimization" schematic uses the old optimization method for EM which is more complicated and time consuming. In the old method, you had to define a variable in the schematic and then optimize the variable. As you can see in the "Old_Discrete_Optimization" schematic, there are two different variables, L1 and L2. These variables have been assigned to the length parameters of the MLEF elements. The reason for using variables instead of simply choosing those two parameters to be optimizable is so we can use discrete optimization. The benefit of using discrete optimization when optimizing an EM structure is that we can set the step size of the discrete variable list to be the same as the cell size of the extracted EM structure. The "L_VECT" vector is defined to set up for discrete optimization. Finally you set L1 and L2 to be optimized.
However in the new method, using the Discrete Local Search Optimizer, all the set up can be done in the Variable Browser. Go to View > Variable Browser and look at the L values for MLEF elements in the "New_Discrete_Optimization" schematic. The Lower, Upper, and Step Size columns are set and the Constrained box is checked.
An optimization goal has been set so that S21 must be less than -10 dB from 4.5 GHz to 8.5 GHz.
Simulation and Optimization
After simulating the schematic, it is clear the filter in its current state is not meeting the optimization goal. At this point the circuit can either be optimized to achieve the goal.
To optimize the circuit, bring up the Optimization window and click the "Start" button. Note that the optimization method is set to "Discrete Local Search". Unlike other optimizers, this optimizer will only search over the discrete set of values determined by the Lower, Upper, and Step Size properties of the optimization variables. While the circuit is being optimized, you can see the layout of the extracted portion of the filter (2D and 3D) changing. Because of the number of frequency points and the nature of EM simulation, it may take up to a minute for the optimizer to reach its goal.
ACE Optimization
Note: In order to utilize this feature, the user must have a license that includes ACE
To change the solver from AXIEM to ACE, simply change the Simulator parameter of the EXTRACT block to "ACE". Also, disable the EM_MESH annotation and enable the EXT_CKT3D annotation.
In the Optimizer window, click on Revert > Initial to reset the dimensions of the filter. Now click "Start" in the Optimizer window or use the tuner to manually tune the circuit. ACE simulation will be much faster than using a standard EM solver.
Tuning on Dielectric Height
One other feature to try is tuning on the dielectric height. In the Global Definitions window, you can see that the parameter for the substrate height in the STACKUP has been defined as a variable, T, which is tunable. If you tune this variable, you can see the change in the filter response and see the dielectric height change in the 3D view of "EM_Extract_Doc".


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Tribune Obituaries
August 21, 2004
Anthony R. "Tony" Garcia, 20, of Greeley died Tuesday, Aug. 17, at his home.
He was born March 9, 1984, in Greeley to Raymond Phillip and Charlotte Ann (Keberlein) Garcia.
Mr. Garcia grew up in Greeley where he attended Madison Elementary, Franklin Middle and Heath Junior High schools and graduated with
his high school diploma from Aims Community College. He enjoyed hunting, fishing, camping and pottery. He loved the outdoors. He enjoyed cooking and computers. He also enjoyed being with his friends and family. Survivors are his mother and stepfather, Charlotte and Thomas DeBrock of Greeley; two brothers, Terry R. Garcia of Florida and Tommy DeBrock of Greeley; numerous aunts and uncles; and a nephew. Memorial services will be at 10 a.m. Monday at St. Peter's Catholic Church, 915 12th St., Greeley. Cremation. Contributions may be made to the Anthony R. Garcia Memorial Fund in care of Northern Colorado Crematory, 700 8th St., Greeley, CO 80631.
Cheryl L. McCorkle, 52, of Fort Lupton died Friday, Aug. 20, at her home. She was born Jan. 29, 1952, in Lexington, Neb., to Donald and Virginia (Styles) Gunn. Mrs. McCorkle lived in Fort Lupton for 30 years. She worked as a baker at the Branding Iron Restaurant for nine years. She enjoyed sports and music and loved her friends and her only grandchild. Survivors are two sons, Stuart McCorkle of Castle Rock and Cory McCorkle of Fort Lupton; a sister, Chrissy Gunn of Bayard, Neb.; a brother, brother, Chuck Gunn of Pine Bluffs, Ariz.; and her grandchild.
Services will be at 10 a.m. Tuesday at Bostick Funeral Home, 806 Denver Ave., Fort Lupton. Interment will be private.
Dorothy Evangeline Miller, 101, of Greeley died Monday, Aug. 16, at Bonell Good Samaritan Center, Greeley. She was born July 16, 1903, in Midway, Pa., to Herbert R. and Minnie Luetta (Kleckner) Morris. Mrs. Miller came to Colorado as a young woman with her family. Her father was a Methodist minister circuit rider and ministered at several of the rural Methodist churches and settled in Greeley.
She graduated from Greeley High School in 1922 and Colorado State Teachers College, now the University of Northern Colorado, in 1926. After two years of teaching, she married her high school sweetheart, Leon Miller, on Sept. 12, 1928. They became Methodist missionaries to Chile and Costa Rica
for 35 years and returned to Greeley when they retired in 1968. The Millers were active in the First United Methodist Church
of Greeley. Mr. Miller died in 1987. Mrs. Miller had been a resident of Bonell since 1994.
Survivors are two daughters, Marguerite "Peggy" Briles of Northampton, Mass., and Katherine "Kitty" Allen
of Thornton; two sons, Theodore "Ted" Miller and wife Phyllis of Banning, Calif., and Gerald "Jerry" Miller and wife MaryLou of Fullerton, Calif.; a sister, Marguerite Mead of Anchorage, Alaska; 11 grandchildren; 17 great-grandchildren; and four great-great grandchildren. Two brothers, Alfred and Everett Morris, are deceased.
Memorial services will be at 10 a.m. Wednesday at the First United Methodist Church of Greeley, 917 10th Ave. Cremation.
Contributions may be made to Bonell Good Samaritan Center or Hospice and Palliative Care of Northern Colorado in care of Allnutt Funeral Service, 702 13th St., Greeley, CO 80631. An obituary and a guest book are at http://www.allnutt.com.
Virginia Mae Titmus, 68, of Evans died Friday, Aug. 20, at her home.
She was born Jan. 1, 1936, in Lamar to Lillard Dave and Allice Louise (Line) Mills.
On July 25, 1964, she married Allen LeRoy Titmus in Greeley.
Mrs. Titmus graduated from Lamar High School in 1953. She enjoyed bowling and playing bingo. Everyone liked her.
Survivors are her husband, LeRoy Titmus Sr. of Evans; six daughters, Janet Lucas
of Amarillo, Texas, Cynthia Powell of Pampa, Texas, Melody Wilder of Garfield, Kan., Melinda Miller and Monica Titmus, both of Evans,
and Sherry Kirkbride of Yuba City, Calif.; two sons, Allen LeRoy Titmus Jr. of Greeley and Robert L. Titmus of Fresno, Calif.; 13 grandchildren; and four great grandchildren.
Also surviving are five sisters, Mary Ferguson of Orcutt, Calif., Shirley Kelly of Mobile, Ala., Bobbie Barkfelt of Visalia, Calif., Carol Simmons of Banning, Calif., and Judy Neel of Dallas, Texas; and a brother, Jimmy Brothers, also of Banning.
A daughter, Pamela Jo Brooks, and a son, Richard A. Brooks, her parents, two sisters, Jessie Bessinger and Betty Lewis, and a brother, Charles Mills, are deceased.
Services will be at 2 p.m. Tuesday at Stoddard Funeral Home. Interment will be in Sunset Memorial Gardens, Greeley.
Friends may visit from 4-7 p.m. Monday at the funeral home.
Contributions may be made to the Virginia Titmus Memorial Fund in care of Stoddard Funeral Home, 3205 W. 28th St., Greeley, CO 80634.
An online memorial is at http://www.mem.com.


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- 100: BROWNFACESUBMIT NOW with W S Dunn 99: SINGAPORECOMING SOON with A Pang and J Ip 97 & 98: PROPAGANDAwith M Breeze and S groth 96: NO THEME IXwith M Gill and J Thayil 95: EARTHwith M Takolander 94: BAYTwith Z Hashem Beck 93: PEACHwith L Van, G Mouratidis, L Toong 92: NO THEME VIIIwith C Gaskin 91: MONSTERwith N Curnow 90: AFRICAN DIASPORAwith S Umar 89: DOMESTICwith N Harkin 88: TRANSQUEERwith S Barnes and Q Eades 87: DIFFICULTwith O Schwartz & H Isemonger 86: NO THEME VIIwith L Gorton 85: PHILIPPINESwith Mookie L and S Lua 84: SUBURBIAwith L Brown and N O'Reilly 83: MATHEMATICSwith F Hile 82: LANDwith J Stuart and J Gibian 81: NEW CARIBBEANwith V Lucien 80: NO THEME VIwith J Beveridge 57.1: EKPHRASTICwith C Atherton and P Hetherington 57: CONFESSIONwith K Glastonbury 56: EXPLODE with D Disney 55.1: DALIT / INDIGENOUSwith M Chakraborty and K MacCarter 55: FUTURE MACHINES with Bella Li 54: NO THEME V with F Wright and O Sakr 53.0: THE END with P Brown 52.0: TOIL with C Jenkins 51.1: UMAMI with L Davies and Lifted Brow 51.0: TRANSTASMAN with B Cassidy 50.0: NO THEME IV with J Tranter 49.1: A BRITISH / IRISH with M Hall and S Seita 49.0: OBSOLETE with T Ryan 48.1: CANADA with K MacCarter and S Rhodes 48.0: CONSTRAINT with C Wakeling 47.0: COLLABORATION with L Armand and H Lambert 46.1: MELBOURNE with M Farrell 46.0: NO THEME III with F Plunkett 45.0: SILENCE with J Owen 44.0: GONDWANALAND with D Motion 43.1: PUMPKIN with K MacCarter 43.0: MASQUE with A Vickery 42.0: NO THEME II with G Ryan 41.1: RATBAGGERY with D Hose 41.0: TRANSPACIFIC with J Rowe and M Nardone 40.1: INDONESIA with K MacCarter 40.0: INTERLOCUTOR with L Hart 39.1: GIBBERBIRD with S Gory 39.0: JACKPOT! with S Wagan Watson 38.0: SYDNEY with A Lorange 37.1: NEBRASKA with S Whalen 37.0: NO THEME! with A Wearne 36.0: ELECTRONICA with J Jones
Fiona Hile
Mosaically Speaking: Pieces of Lionel Fogarty's Poetics
As the Hong Kong riots reach their sixth consecutive week, I'm emailing a friend at Hong Kong University who writes about liberty and subjection.
Posted in ESSAYS Tagged Dashiell Moore, Fiona Hile, Lionel Fogarty, Tyne Daile Sumner
Introduction to Elena Gomez's Body of Work
There's a difference between occupying a seemingly unceasing parade of subject positions through a kind of colonising, thieving, dissipatory borderlessness … and inhabiting them as a form of aesthetic and political revolt.
Posted in GUNCOTTON Tagged Elena Gomez, Fiona Hile, Zoë Sadokierski
Sandra D'Urso Interviews Fiona Hile
To read Hile's poetry is to encounter what it means to be a desiring subject in a contemporary world. Her use of vernacular recalls and transforms the details of everyday life, while gesturing toward the grand themes of a European philosophical tradition.
Posted in INTERVIEWS Tagged Alain Badiou, Anne Carson, Fiona Hile, Jacques Derrida, Julia Kristeva, Sandra D'Urso, Shulamith Firestone
MATHEMATICS Editorial
I was already quite a few years into a creative writing PhD titled 'Generic Engineering' and flailing around quite spectacularly in a galaxy of words when an academic friend, perhaps hoping to spare me the indignity of a completed thesis and potential employment, flipped to the middle of the 526-page book he was reading and wordlessly pointed to a single sentence. 'Due to a predilection whose origin I will leave it up to the reader to determine,' he read, 'I will choose the symbol ♀ for this inscription.'
Posted in ESSAYS Tagged Alain Badiou, Fiona Hile, Justin Clemens, Rachel Blau DuPlessis
Submission to Cordite 83: MATHEMATICS
The invention of transfinite set theory by the 19th Century German mathematician, Georg Cantor, hinges the romantic conception of a boundless infinite to a post-Cantorian description of an infinity of infinities.
Posted in GUNCOTTON Tagged Fiona Hile, Georg Cantor, Kent MacCarter
dictate your every word, you bright nymphs mistake the possible. Thank you for the plangent note, the sacrifices that were not at all intended as an offering. The snare you prepared with the guile of an anxious siren. If I …
Posted in 53.0: THE END Tagged Fiona Hile
Every star has its double, different coloured blood cometing at length. How you will defeat me, with a scythe or a ladder, a hoked up piece of trash untucked beneath a raging plinth. Your feelings, juiced on perforated, in which …
Posted in 50.0: NO THEME IV Tagged Fiona Hile
Fiona Hile Reviews Lionel Fogarty
Lionel G. Fogarty is an indigenous Australian poet who is recognised for the excavation of a poetic space in which, as Michael Brennan has written, 'his community and culture is recuperated and asserted' whilst 'dominant discourses, both political and poetic' are subverted and destabilised. These qualities make Fogarty's work difficult to review in a context in which the status of indigenous literature remains, for some institutions at least, seemingly unapproachable.
Posted in BOOK REVIEWS Tagged Alain Badiou, Andrew Reimer, Daniel Boyarin, Fiona Hile, Giorgio Agamben, Lionel Fogarty, Pam Brown
Review Short: Andrew Burke's One Hour Seeds Another and Nicola Bowery's married to this ground
Addressing the quotidian in writing is an ongoing practice for many poets. Andrew Burke's One Hour Seeds Another and Nicola Bowery's married to this ground approach this preoccupation with a robust commitment and urge to render it lucidly, but each is in conversation with different lineages. Burke's cycle is cross-fertilised with jazz and folk music, with Hindu and Buddhist references, with playful abstraction, but it is the intentional elegiac timbre in this collection that lingers in the reader's mind.
Posted in BOOK REVIEWS Tagged Andrew Burke, Antonia Pont, Fiona Hile, Nicola Bowery
The Satisfaction of Speech
Stretched out across the selfish wool table, I fix on a mood in the high key of you, twiddle my hi-viz wedding ring and laugh at the way rhyme and metre protect us from happiness. Angels' tears fill the rivers …
Posted in 46.1: MELBOURNE Tagged Fiona Hile
Review Short: Fiona Hile's Novelties
In Lacanian theory, 'matheme' and 'patheme' share an interesting correlation. While the matheme is, obviously, on the side of science, the patheme is part of the 'logics' of affect, whereby the body is an effect of language. Matheme and patheme don't immediately have anything to do with sexual difference or 'mechanistic' versus 'organicist' understandings of the universe. There is nothing mysterious about the patheme. Rather, the patheme could be thought of as what the poem does to the poet's body analogously to what a matheme does to a mathematician's body: force it to work and, in some cases, give it pain.
Posted in BOOK REVIEWS Tagged Andrew Carruthers, Fiona Hile
(Notes from a Lecture Delivered by a Former English Poet Laureate) At the age of six you were a bloody little genius Bauxite was the only word you could spell But I knew the year of the Battle of Hastings …
Posted in 42.0: NO THEME II Tagged Fiona Hile


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The Grosvenor Pine Range furniture is beautifully crafted from New Zealand pine with traditional dovetail joints, tongue and grove pine linings with deep drawers for storage. This range is affordable, elegant with a hand waxed finished to bring out the warm colour of the New Zealand pine and a smooth surface finish.
Grosvenor Pine: Pedistal Dressing Table drawer internal dimension 16cm (6.5 inches) deep.
|42 x 104 x 74 cm


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Australian made performance ProForm™ with Added High iQ™ Cool Comfort. Comfortable and lightweight fabric, up to three times more durable than natural fibres; added High iQ™ Cool Comfort transports the moisture from your skin to the fabric's surface resulting in rapid evaporation, keeping you cool and dry.
Contrast Cross Band.


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New Research In
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CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization
Communicated by Barry R. Bloom, Harvard School of Public Health, Boston, MA, February 14, 2005 (received for review December 7, 2004)
Acquired immunity to Streptococcus pneumoniae (pneumococcus) has long been assumed to depend on the presence of anticapsular antibodies. We found, however, that colonization with live pneumococci of serotypes 6B, 7F, or 14 protected mice against recolonization by any of the serotypes and that protection from acquisition of a heterologous or homologous strain did not depend on anticapsular antibody. Further, intranasal immunization by live pneumococcal colonization or by a killed, nonencapsulated whole-cell vaccine protected antibody-deficient mice against colonization, suggesting independence of antibodies to any pneumococcal antigens. Protection by intranasal immunization with whole-cell vaccine was completely abrogated in T cell-deficient mice, and in mice that were congenitally deficient in CD4+ T cells or depleted of these cells at the time of challenge. In contrast, mice congenitally deficient in, or depleted of, CD8+ T cells were fully protected. Protection in this model was observed beyond 2 months after immunization, arguing against innate or nonspecific immune mechanisms. Thus, we find that immunity to pneumococcal colonization can be induced in the absence of antibody, independent of the capsular type, and this protection requires the presence of CD4+ T cells at the time of challenge.
Almost 1 million children in the developing world die of infections due to Streptococcus pneumoniae (pneumococcus) each year (1). Pneumococcus is considered an "extracellular" bacterial pathogen, i.e., it is killed upon ingestion by phagocytic cells. Ingestion is facilitated by antibody (Ab) to its capsular polysaccharides (PS), of which there are at least 90 different serotypes. The two existing pneumococcal vaccines are based on injected mixtures of PS. Plain (unconjugated) PS vaccine contains 23 serotypes but is not efficacious in children <2 years old and therefore fails to protect those at highest risk. Protein-conjugated PS contains seven serotypes and protects infants (2), but it is difficult to manufacture (resulting in repeated shortages), is expensive, needs refrigeration, requires multiple injections, and does not include many of the capsular serotypes that cause pneumococcal disease in the developing world. Furthermore, serotype replacement, whereby pneumococcal serotypes not included in the conjugate vaccine become more prevalent causes of colonization and disease, has already been observed in clinical trials (3) and in epidemiologic studies (4) after implementation of conjugate vaccine immunization programs. Therefore, despite the success of the capsule-based vaccines, alternative strategies are urgently needed.
The success of serum therapy (passive transfer of anticapsular Ab from hyperimmune animals) and the efficacy of PS and PS-protein conjugate vaccines have clearly demonstrated that anticapsular Ab alone is sufficient to treat or prevent pneumococcal disease. Furthermore, studies in animals (5) and humans (6) clearly demonstrate that anticapsular Abs can protect against nasopharyngeal pneumococcal colonization, which precedes pneumococcal disease (7). However, several observations suggest the hypothesis that natural immunity to colonization might nonetheless be acquired independently of anticapsular Ab. The age-specific incidence of pneumococcal disease in humans declines simultaneously and in a parallel fashion for a wide range of serotypes and well before natural acquisition of anticapsular Abs (8), suggesting a common and probably capsular serotype-independent mechanism of protection. Additionally, we have previously shown that a vaccine made from killed, unencapsulated pneumococci whole-cell vaccine (WCV) given intranasally to mice with cholera toxin (CT) as an adjuvant prevents colonization by pneumococci of various capsular serotypes (9, 10). More recently, McCool and Weiser (11) reported that clearance of carriage of a recently acquired pneumococcal strain in mice could occur independently of Ab, further supporting the possibility that other components of the immune response (whether innate or acquired, specific or not) may play an important role in this process, but the mechanisms for this protection have not been elucidated to date.
The purpose of our studies was to identify immunologic mechanisms of prevention of pneumococcal colonization. Here, we show that long-lasting immunity to pneumococcal colonization can be conferred independently of immunity to the PS capsule, in a fashion that is Ab-independent but dependent on CD4+ T cells present at the time of challenge. Protection conferred by these T cells was observed >2 months beyond immunization, arguing against nonspecific or innate responses. Our data therefore indicate a previously unrecognized, critical role for cellular immunity, independent of Ab, in the prevention of colonization by pneumococcus.
Bacterial Strains and Immunogens. S. pneumoniae strains TIGR4J, TIGR4:6B4, TIGR4:7F4, and TIGR4:144 are isogenic variants (12) of S. pneumoniae strain TIGR4. TIGR4J is acapsular; the other strains express serotype 6B, 7F, or 14 capsules, respectively (12). Strain 0603 is a serotype 6B clinical strain (9). Frozen midlog-phase aliquots were thawed and diluted to ≈106 colony-forming units (cfu) per 10 μl of intranasal inoculum for challenge. WCV was derived from strain RX1AL-, a capsule- and autolysin-negative mutant, and prepared as described in ref. 9. The final vaccine mixture contained 108 (killed) cfu of this strain plus 1 μg of CT (List Biological Laboratories, Campbell, CA) per 10-μl dose. Control mice were immunized with 1 μg of CT in 10 μl of saline.
Animal Models. To assess the role of capsular serotype in protection against nasopharyngeal carriage, groups of 20 C57BL/6J mice (female, age 6 weeks, The Jackson Laboratories) were randomized by cage to receive ≈106 cfu of TIGR4:6B4, TIGR4:7F4, TIGR4:144, or saline control, as described in ref. 9. Inoculations were given three times at weekly intervals. One week after the last inoculation, two i.p. injections of 1 mg of rifampin (Sigma) in 0.25 ml were provided 1 day apart [a dose that effectively eradicates pneumococcal colonization and does not prevent subsequent colonization (data not shown)]. Two weeks later, serum and saliva samples were obtained from anesthetized mice. Salivation was induced by i.p injection of 100 μg of pilocarpine (Sigma). Saliva was kept on ice, an equal volume of 1× PBS containing 5% FCS (HyClone) and 12.5 μg/ml aprotinin (Sigma) was added, and samples were frozen at -70°C until use. Mice were challenged intranasally with ≈106 cfu of one of the TIGR4 serotype variants. At 1 week after challenge, the mice were killed by CO2 inhalation; an upper respiratory wash was performed by instilling sterile, nonbacteriostatic saline retrograde through the transected trachea and collecting the first six drops (≈0.1 ml) from the nostrils. An animal was considered to be nasally colonized if at least 1 cfu per 100 μl of wash fluid was detected.
To test the role of Ab in protection, C57BL/6J, muMT-/- [B6.129S2-Igh-6tm1Cgn/J, in which B cell development is blocked at the pro-B stage (13)], nu -/- (nude mice, lacking T cells) and their respective nu +/- littermates were obtained from The Jackson Laboratories. β2-microglobulin (β2m)-deficient mice [B6.129-B2mtm1 N5 (14)] and MHC Class II-deficient mice [B6.129-H2-Ab1tm1Gru N12, with a disruption of the H2-Ab1 gene (15)] were purchased from Taconic Farms; these mice lack CD8+ and CD4+ T cells, respectively. Mice were randomized by cage to receive vaccine or control preparations (live 0603, killed WCV/CT, CT alone, or saline; mice lacking T cells or T cell subsets received only WCV/CT or CT). Immunization was delivered as described above except for the concentration of bacteria (106 cfu of 0603; 108 cfu of killed WCV/CT). Inoculations were given at weekly intervals (thrice for strain 0603 and saline; twice for WCV/CT or CT). Only the mice that received strain 0603 or saline received rifampin treatment. All mice were challenged with 106 cfu of strain 0603 (3 weeks after immunization with WCV/CT or CT; 2 weeks after rifampin treatment for mice that received strain 0603 or saline). One week after challenge, mice were killed, and nasal wash was obtained as above.
To test the role of T cell subsets at the time of challenge and also to evaluate whether protection was long-lasting, the same protocol with WCV/CT or CT was followed as above, except that the pneumococcal challenge was performed 10 weeks after the last immunization. One group of mice (n = 16) received intranasal CT, and four groups received WCV/CT (n = 12-16 for each group). To deplete T cell populations, three groups of WCV/CT mice were administered 1 mg of Abs 1 day before, 1 day after, and 4 days after the challenge (16). A control group received rat IgG (Calbiochem), whereas experimental groups received either rat anti-mouse CD4 monoclonal IgG2b (purified from hybridoma GK1.5, American Type Culture Collection) or rat anti-mouse CD8 monoclonal IgG2a (purified from hybridoma 53-6.72, American Type Culture Collection). More than 95% of CD4+ or CD8+ T cells were depleted from the spleens of respectively treated animals, as assessed by flow cytometry.
ELISA. ELISAs were performed on serum and saliva samples collected before exposure to the challenge strain. A subset of at least 10 mice exposed to serotype 6B, 7F, or 14 or saline was evaluated for salivary IgA and serum IgG and IgM Abs to capsular PS 6B, 7F, and 14. In this case, saliva and serum samples were preabsorbed with both C-PS and type 22F capsular PS at a concentration of 5 μg/ml. MuMT-/- mice were evaluated for Ig and IgG (serum) Abs to whole cells of strain TIGR4J and IgA (saliva) Abs to the pneumococcal proteins PsaA and PspA and to TIGR4J. Whole-cell ELISA was performed as follows. TIGR4J strain was grown in THY to late-log phase, harvested by centrifugation, killed by 1-h incubation in 70% EtOH (vol/vol), and washed extensively to remove any residual EtOH. Ninety-six-well ELISA plates were coated overnight with 0.1 ml of this killed TIGR4J preparation (corresponding to a concentration of 108 cfu/ml). After blocking in PBS/Tween (0.05%) with 5% FCS, dilutions of serum or saliva were added and incubated at room temperature for 2 h. Plates were washed, and secondary Ab to mouse Ig was added and incubated at room temperature for 1 h. The plates were washed and developed with SureBlue 3,3′5,5′-tetramethylbenzidine microwell peroxidase substrate (Kirkegaard & Perry Laboratories).
Statistical Analysis. Proportions colonized were compared by Fisher's exact test, and colonization density was evaluated by the Mann-Whitney U test or by the Kruskal-Wallis test with Dunn's correction for multiple comparisons.
Prior Exposure to Homologous and Heterologous Capsular Serotypes Confers Similar Protection Against Subsequent Pneumococcal Colonization. The role of capsule in immunity to colonization was examined. C57BL/6J mice were intranasally inoculated thrice at weekly intervals with 106 cfu of serotype 6B, 7F, or 14 variants of pneumococcal strain TIGR4, which were isogenic except for the cps locus (12). A week later, colonization was cleared with rifampin treatment (9). Two weeks afterward, mice of each group were challenged intranasally with 106 cfu of one each of the three strains. One week later, colonization was assessed by tracheal wash. Fig. 1 shows the proportion of animals colonized with each serotype, with naïve (saline controls) compared with animals that had previously been exposed to one of the three strains. Prior colonization offered protection ranging from 24% to 93%, but not statistically greater with the homologous than with the two heterologous serotypes. Consistent with this finding, no anticapsular Ab was measurable in serum or saliva obtained from animals before the final challenge (9), suggesting that the mechanism of protection is independent of such Abs. Therefore, these studies show that exposure to homologous and heterologous capsular serotypes confer similar protection against subsequent pneumococcal colonization, suggesting that immunity to the capsular PS does not play a critical role in prevention of colonization.
Prevention of Pneumococcal Colonization Is Independent of Ab. Next, we evaluated whether Abs of any specificity were involved in prevention of pneumococcal colonization in this model. Immunization was performed by exposure to live pneumococci (as described above) and also by intranasal vaccination with a killed, unencapsulated pneumococcal preparation (WCV) that we previously demonstrated to be highly effective in the prevention of pneumococcal colonization due to several different serotypes (9, 10). MuMT-/- (Ab-deficient) mice were immunized intranasally, either thrice with live serotype 6B pneumococcus strain 0603 (followed by rifampin treatment as above) or twice with WCV with CT as an adjuvant. Four weeks after immunization, mice were challenged intranasally with strain 0603. Colonization evaluated 7 days after challenge was significantly reduced by the previous exposure to live strain 0603 and almost completely prevented by the immunization with WCV/CT (Fig. 2). No serum or salivary Ab to pneumococcal antigens was detected, confirming that protection against colonization in this model is independent of systemic and mucosal Ab.
Immunity to Pneumococcal Colonization Depends on CD4+ T Cells, Which Must Be Present at the Time of Challenge. Because immunity to colonization elicited by the WCV is long-lasting [complete protection against colonization is observed >2 months since the last immunization (9)], we hypothesized that cognate T cells may be playing a role in protection. Therefore, to test T cell dependence of the protection, the vaccination protocol with WCV (9) was repeated in the following types of mice: (i) T cell-deficient (nu -/-) and heterozygote control (nu +/-) mice; (ii) β2m-deficient (β2m-/-) mice that lack CD8+ T cells (14); and (iii) MHC Class II-deficient mice (H2-Abl-/-) that lack CD4+ T cells (15). As in the case of wild-type (WT) mice, protection was observed in the heterozygote controls and in the β2m-/- mice, but was completely abrogated in the nu -/- and H2-Abl-/- mice (Fig. 3). It is noteworthy that CD4+ T cell-deficient mice that received CT only (and thus were naïve to pneumococci) were no more heavily colonized than CD8+ T cell-deficient mice immunized with CT. These data, which do not indicate an important role for naïve CD4+ T cells in the prevention of nasopharyngeal colonization, are in contrast with findings by Kadioglu et al. (17) suggesting a role of naïve CD4+ T cells in the protection against invasive disease. Overall, these results suggested that, after mucosal exposure to pneumococci, CD4+ T cells may be required for protection against pneumococcal colonization.
To assess whether CD4+ T cells were required at the time of challenge as part of the mechanism of protection, C57BL/6 mice were immunized with WCV as before and, 10 weeks after the second immunization, were selectively depleted of CD4+ or CD8+ cells, by using anti-CD4 or -CD8 monoclonal Abs. Control groups received intranasal CT alone or WCV/CT followed by treatment with irrelevant Ab or no Ab. Mice that received WCV/CT were all significantly protected against pneumococcal colonization except those that were depleted of CD4+ T cells (Fig. 4). Because T cell depletion was performed >2 months after immunization, these results argue strongly against nonspecific, innate responses to immunization and suggest a role of acquired immunity mediated by CD4+ T cells at the time of challenge.
Immunity to extracellular, encapsulated bacteria has long been assumed to depend on the humoral arm of the immune system. In the case of pneumococcus in particular, immunity to disease and colonization generally has been associated with Abs to the main virulence factor of the organism, the capsular PS. This concept has even led to the conclusion that, from the perspective of the host immune system, each different pneumococcal serotype represents a different potential pathogen, as determined predominantly by the capsular PS (18). Recently, however, data derived from two different approaches have challenged this generally accepted view. Data from sero-epidemiologic studies argue against a primary role of anticapsular Ab in the prevention of pneumococcal disease (8). Unimmunized children demonstrate a significant reduction in susceptibility to pneumococcal invasive disease before the development of measurable systemic anticapsular Abs. Secondly, this age-related decline in pneumococcal invasive disease is observed across serotypes, arguing strongly for a serotype-independent, common mechanism of protection. In a murine model of pneumococcal colonization, McCool and Weiser (11) demonstrated that clearance of pneumococcal carriage did not depend on the presence of Ab, because Ab-deficient mice were able to clear pneumococcal colonization similarly to WT mice, although the responsible mechanisms were not elucidated.
The data presented herein suggest an Ab-independent, CD4+ T cell-dependent mechanism by which immunity to pneumococcal colonization can be acquired after exposure to pneumococci. To our knowledge, such a mechanism of protection against extracellular, encapsulated bacteria has not previously been demonstrated. Although T cell help is required for the primary induction of an anticapsular Ab response by capsular PS-protein conjugate vaccines, it is the Abs induced by such vaccines that are the effectors of immunity. Moreover, the T cell help is required at the time of immunization with conjugate vaccines, to induce affinity maturation, class switching, and B cell memory (19, 20), but may not be required at the time of challenge, as it is in the experiments described here. Stimulation of antigen-specific CD4+ T cells by Group A streptococci has recently been described, but no evidence for a protective role of these cells was obtained (21).
The role of CD4+ T cells in pneumococcal pathogenesis has been evaluated in other studies. Kadioglu et al. (17) have shown that mice lacking CD4+ T cells due to a deletion of MHC Class II are compromised in host defense against systemic pneumococcal challenge in the first 3 days after infection. These studies were conducted in naïve mice. By contrast, in our colonization model, MHC Class II-deficient mice exposed to CT only (and thus naïve to pneumococcus) were no more heavily colonized than controls that lacked CD8+ T cells. Thus, whereas Kadioglu et al. (17) showed the importance of CD4+ T cells in primary clearance of pneumococci during invasive disease in naïve mice, we have shown the involvement of CD4+ T cells in a long-lasting, acquired immune response. Kadioglu et al. (17, 22) also showed that T cells are rapidly recruited after pneumococcal pulmonary infection and that human CD4+ T cells migrate toward pneumococci in vitro, in a fashion that depends, at least in part, on the cytotoxin pneumolysin. It would be valuable to understand to what extent the induction of acquired immunity during initial exposure to live or killed pneumococci in our system depends on migration and activation of CD4+ T cells through a pneumolysin-dependent mechanism of the sort described by Kadioglu et al. (17, 22).
Thus, in mice, nonserotype-specific resistance to colonization can be induced by intranasal exposure to live or killed bacteria in the absence of anticapsular Ab and, more surprisingly, without Ab of any specificity. Instead, long-lasting WCV-induced immunity is mediated by CD4+ T cells. It remains to be determined how closely our non-type-specific immunization by intranasal inoculation models the acquisition of natural immunity and whether this CD4+ T cell-dependent phenomenon occurs in humans. Individuals with profound Ab deficiency (such as Bruton's agammaglobulinemia) are known to be at high risk for invasive pneumococcal disease (23), but whether there is like-wise a high risk of nasopharyngeal colonization is not clear. Moreover, it is unknown whether the critical defect in such Ab-deficient individuals involves anticapsular Ab or Ab against one or more other pneumococcal antigens.
Anticapsular Abs not only prevent invasion but, as shown by active and passive immunization (5, 24), are sufficient to prevent pneumococcal colonization; however, they may not be necessary. As mentioned above, children naturally acquire resistance to invasive disease from all serotypes on a similar timescale and before the appearance of anticapsular Abs, suggesting that other immune effectors may be involved. Abs to noncapsular antigens are sufficient in some animal models to protect against colonization or invasive disease, but the role of these Abs in natural protection in humans is also uncertain. In normal children, colonization persists in the first years of life, despite the appearance of such Abs (25), which thus might merely be markers of exposure, not effectors of protection.
During invasive disease, the pneumococcus is shielded by its PS capsule against phagocytosis (26). The phenotype of pneumococci colonizing the nasopharynx, however, differs in several respects from that of pneumococci causing invasive disease, including reduced expression of capsular PS and increased expression of certain noncapsular antigens (27). Further elucidation of the role of T cells in defense against pneumococcal colonization will require an assessment of whether these T cells are responding to antigens from pneumococci that have been internalized by professional antigen-presenting cells and/or epithelial cells (28), as well as identification of the antigen(s) involved.
The precise mechanisms whereby CD4+ T cells may effect protection against colonization remain to be determined. One possibility is that the CD4+ T cells protect against pneumococcal colonization by generating a T helper 1 (Th1)-type response, a process similar to that shown to protect against "intracellular" bacteria such as Listeria, Salmonella, and mycobacteria (29, 30). Our previous finding that the preservation of a Toll-like receptor 4 ligand in the WCV is critical for protection (ref. 31 and R.M., unpublished data) is consistent with this hypothesis, because Toll-like receptor 4 ligands have been shown to bias toward T helper 1-type responses (32). Another potential mechanism, independent of T helper 1 or 2 profile, may be IL-17A-producing CD4+ T cells, which have been shown to mobilize neutrophils through granulopoeisis and chemokine induction (33). Recent data suggest that IL-17A release by these T cells depends on dendritic cells producing IL-23 through Toll-like receptor-dependent pathways (34).
Limited serotype coverage and cost restrict the usefulness of the oligovalent conjugated capsular vaccine for childhood disease prevention worldwide, and therefore more economical modes of immunization are urgently needed. It may be useful to evaluate vaccination strategies based on mechanisms of naturally acquired immunity to colonization and specifically based on the Ab-independent immunity demonstrated here. Vaccines that reduce carriage and induce herd immunity against pneumococcus, based on antigens shared among serotypes, may represent a viable strategy to reduce the burden of disease in both developed and developing countries. Despite the fact that the heptavalent PS conjugate vaccine offers only partial protection against a limited range of serotypes (24), it appears already to have prevented a substantial amount of disease by means of its indirect effects on transmission to nonvaccinated age groups (35); this experience suggests that a vaccine that offered better protection against carriage of a wider range of serotypes could have a major impact on disease, not only in those who are vaccinated but in other groups as well. A number of the noncapsular antigens have been proposed as vaccines, but have not yet been demonstrated to have efficacy in humans (36). We had previously shown that WCV has the ability to stimulate Ab responses to multiple antigens and that these Ab responses can protect against invasive disease (9). Here, we have shown that WCV additionally stimulates Ab-independent, CD4+ T cell-dependent immune responses that are protective against asymptomatic carriage. Furthermore, the WCV has properties that suggest excellent potential for developing countries: low cost, mucosal administration, and broad coverage. It will be of great interest also to see whether the WCV (given intranasally with a suitable mucosal adjuvant) will protect humans as well as mice against colonization.
We thank B. Bloom, E. Kurt-Jones, J. Rengarajan, M. Starnbach, M. Swamy, A. Tzianabos, and M. Wessels for helpful discussions during the course of this work; M. Rojas-Lopez for assistance with flow cytometry; and Eddie Ades (Centers for Disease Control, Atlanta) and Susan Hollingshead (University of Alabama, Birmigham, AL) for providing recombinant protein antigens for ELISA. R.M. was supported by the Meningitis Research Foundation and National Institutes of Health Grant K08 AI51526-01. A.S. was supported by National Institutes of Health Training Grant AI07061-26. M.L., C.M.T., and K.T. were supported by National Institutes of Health Grant 5 R01 AI048935.
↵ † To whom correspondence should be addressed at: Division of Infectious Diseases, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115. E-mail: richard.malley{at}childrens.harvard.edu.
Author contributions: R.M., P.W.A., and M.L. designed research; R.M., K.T., A.S., C.M.T., and M.L. performed research; R.M., K.T., A.S., C.M.T., P.W.A., and M.L. analyzed data; and R.M. and M.L. wrote the paper.
Abbreviations: β2m, β2-microglobulin; cfu, colony-forming units; CT, cholera toxin; PS, polysaccharide; WCV, whole-cell vaccine.
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Lewis Hamilton takes Formula One drivers' championship lead with Italian Grand Prix win
Sixth win of season and 59th triumph of his career sees the Mercedes-GP driver go three points clear of Sebastian Vettel.
Lewis Hamilton won the Italian Grand Prix at Monza to take the lead of the Formula One drivers' championship for the first time in 2017.
The triple world champion dominated the 53-lap race to take the chequered flag by 5.5 seconds ahead of his Mercedes-GP teammate Valtteri Bottas.
Hamilton's championship rival Sebastian Vettel was third home in his Ferrari, and the result saw the Briton turn a seven-point deficit to the German into a three-point lead with seven races of the year remaining.
⚫⚫⚫⚫⚫— Formula 1 (@F1) September 3, 2017
Hamilton has now won six races this season, and coming on the back of last weekend's success in Belgium he is the first driver to have back-to-back wins in 2017.
Daniel Ricciardo produced one of the performances of the day as the Red Bull Racing driver came through from 16th on the grid to finish fourth. A mixture of good overtaking and a long first stint in a race where the majority of the field only pitted once, saw him make up the ground.
BREAKING: @LewisHamilton wins at Monza to take the lead in the drivers' championship #ItalianGP 🇮🇹 #F1 pic.twitter.com/Sk2ikB1dlh— Formula 1 (@F1) September 3, 2017
Kimi Raikkonen's Ferrari was fifth, ahead of Esteban Ocon's Force India and the two Williams cars of Lance Stroll and Felipe Massa.
Max Verstappen recovered from a puncture after contact with Massa to finish 10th, one place behind the second Force India of Sergio Perez.
The next round of the season is in Singapore on September 17, with the final race of the year, the Etihad Airways Abu Dhabi Grand Prix, on November 26 at Yas Marina Circuit.
Updated: September 3, 2017 05:21 PM


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Great article from Chris Coyne [@malgorithms]. Full article here: https://keybase.io/blog/2014-10-08/the-horror-of-a-secure-golden-key
A key takeaway:
What you consider cool today might be an embarrassment or personal risk tomorrow. A photo you can rip to pieces, a letter you can shred, a diary you can burn, an old flag you can take out into the woods with your friends and shoot with a bb-gun till it's destroyed and then have a nice, cold beer to celebrate. Cheers to that.
But memories in the cloud are there forever. You will never be able to destroy them. That data is backed-up, distributed, redundant, and permanent. I can tell you first-hand: do not assume that when you click "delete" a file is gone. Take Mary Winstead's word for it. Bugs and tape backups often keep things around, regardless of the law or programmer effort. This is one of the single hairiest technical problems of today.
Instead, how can you burn that digital love letter, or tear up that digital picture? The only answer is to start with it encrypted, and then throw away the only key.
You need the legal right to use software that makes you the sole owner of that key.


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I'm at a little bit of a crossroads.
I've used Plaxo for several years, even through the "those guys are spammers" times. I've always benefited and enjoyed the service they offer. More than once they've saved me from inadvertent stupidity and a deleted Address Book. Now they've released their updated Plaxo 3.0 service and are launching their social networking service also.
All good, right?
Then there's Google. I've never been much of a Gmail user. I use my Gmail address to subscribe to lists, mostly. I don't ever use Gmail in a browser – I'm totally happy with Apple Mail and what it does for me, and I've usually got my MacBook Pro on hand. But Google Calendar is cool. I subscribe to several calendars for different things including my posting schedule for Web Worker Daily – Judi has us on a short leash ;) – and I use Spanning Sync to keep iCal and Google Calendar on the same page.
But coordination! Oh, my. I don't know whether it's me and some oddness I'm creating, but when I have iCal, Plaxo and Google Calendar trying to coordinate with each other, I frequently end up with multiple instances of the same event in my calendar.
My kingdom for a calendar solution that syncs everywhere, is social and doesn't make a mess!


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Gee, where have I heard this before?Full Story... →
How Do You Dial Back Opening the Gates of Hell?
John McCain is now in a very interesting position. Having lost the American people to an economic crisis and his foreign policy wheelhouse having been taken away from him by circumstance and blunder, McCain set off on a course that didn't quite square with his deeply held personal beliefs of how to conduct oneself with honor and dignity. Indeed the firestorm of personal attacks against Barack Obama and the narrative that he is dangerous, pals with terrorists, and can't be trusted was a hardball negative campaign tactic that surely must have been thrust upon John by the Steve Schmidt's […]Full Story... →
John McCain: Unfit to Lead
Hooray YouTube indy political ads! So much good stuff on our side:
(ht BI)Full Story... →
Memo to Team Obama: Listen to teh YouTubes!
YouTube member CartwrightDale says of his ad concept:
Although I enjoyed Barack Obama's recent web ad "Embrace" (the one with lots of hugging between Bush and McCain), I still think the campaign needs to be a little harsher. The idea of a continuation of Bush policies into a third term should be scary, not playful. Furthermore, I think it's important to emphasize that McCain has been "doubling down" on Bush's policies at the same time the rest of the nation (and world) has been abandoning them.
I created this ad to illustrate the kind of concept I'd like to […]Full Story... →
WMD's 3 Questions Episode 1: Pure Hilarity
Update 2: The video has been salvaged!
Update: Sadly, they've decided to pull the video. It is no longer available. But never fear! Uncle Eric is here! Details forthcoming.
Probably not the kind of pure hilarity they were aiming for, but pure hilarity still. I am so anxious for episode 2! Kinda jonesin' already for it.
I'd comment, but I'm speechless.Full Story... →
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In 2006, the western-themed Wild ARMs series entered its fourth installment, and with it came a radical change in the series' combat. Blending traditional RPG conventions with small-scale tactical combat, Wild ARMs 4's HEX combat system was creative and thoroughly enjoyable. Wild ARMs XF (pronounced Crossfire) is an SRPG spin-off of this series, and if the first few hours are any indication, it looks to be an excellent and unusual tactical experience.
so we get more japanese titles localized in the US! From what I've played so far the game is pretty good especially for RPG/strat-RPG fans.


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About Mark Z Miller
Mark Z Miller is a published author. A published credit of Mark Z Miller is The Secret Generate Extra Cash, Inner Game and Accounting & Finance for Friendship Rings Web Biz 3 Course + Resource Guide.To edit or update the above biography on Mark Z Miller, please Log In or Register.
Link to this page: https://www.jacketflap.com/mark-z-miller/105101
Published Works by Mark Z MillerClick a book's title or cover for more details and to read reviews
|Title, Creators, Comments / Reviews
|Date Published
|1. The Secret Generate Extra Cash, Inner Game and Accounting & Finance for ...
Author: Mark Z Miller
Publisher: LTBR, Inc
|Add Review
|Bestselling order determined by Amazon.com SalesRank(tm)


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BOGUE BANKS — Long-period waves, those with a greater than normal distance from crest to crest, race up the beach to the dune line Sunday at Fort Macon State Park just before high tide.
Video shows the effects at the park just after 9 a.m.
Greg Rudolph with the Carteret County Shore Protection Office, which surveys beach erosion and manages renourishment projects, said long-period waves force the water far up the beach well ahead of any hurricane, and at high tide, water may approach or reach the dunes, as was the case Sunday morning.
"Like clockwork this started occurring late Saturday," Rudolph stated in comments he shared Monday with the county Beach Commission and with Coastal Review Online.
He said the waves' arrival was confirmed in data from the Onslow Bay buoy No. LEJ3.
Rudolph said that photos would be taken Tuesday morning and after the storm has passed at customary points along Bogue Banks for comparison to assess any erosion damage to the beach.
Like This Story?
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Joss and Main Coupons & Promo Codes 2020
Joss And Main is a online store that offers exclusive sales on the world's best brands for your home and life. Joss And Main provides finest designers, looks, and brands for your home, at remarkable savings every day. Sign up now on Joss And Main to find best deals & offerings each day!
Frugaa > Stores > Joss and Main: 2 Active Coupons Found
Joss and Main: 3 Unreliable Coupons Found
About Joss and Main
Joss and Main is an online furniture and home goods retailer who offers limited time only deals to its members. In order to shop their great, low priced deals, consumers must join the site, which is free of charge, by inputting their email address on the main page. Members will be updated daily about the exclusive deals that move quickly and are on-time offers as long as supplies last. Shoppers receive access to the highest quality furniture, home accents, décor, housewares and lifestyle accessories that can be as much as 70% off the regular retail price. Joss and Main is the child company of Wayfair, an e-commerce furniture business established in 2002 headquartered in Boston, Massachusetts. Wayfair LLC operates its retail corporations in the United States, the United Kingdom, Australia, Ireland, and Germany.
Wayfair LLC and Joss and Main pride themselves on offering the best deals and service to their customers. For that reason, the customer service team will cater to your every need and inquiry by helping with order details, inventory questions, shipping and installation options, cancellations, returns, and refunds and more. Shopping at Joss and Main will allow you to put your best foot forward when it comes to a stylish home that will look like it cost a fortune, but in reality cost a fraction of what the high end designers normally charge through other retail vendors. It's sister companies, AllModern, Birch Lane, and DwellStudio all sell furniture and home goods and décor at affordable prices.
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- Furniture: Dress every room in your house from the bedroom, living room, dining room, and more. Everything from tables, chairs, couches, armoires, china cabinets, and more.
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For more collection of furniture and home décor products from other well known retailers you can shop at our site that provides huge money savings coupons.
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Shop for the products you want to purchase by visiting the website. Add it to shopping cart and click checkout. Once you add an item to your cart, you'll be given the sale price you know and love. Enter the available promo or coupon code in the box provided. Next add your shipping and billing address and proceed to payment.
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Contact Info
4 Copley Place, Floor 7
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John Dumelo won the baby jackpot because whilst most people have to wait nine months to have a baby, the actor was able to do so in only five months.
John married Gifty Mawuenya in May and in October, they have already welcomed their first child together. This has left Ghanaians scratching their heads trying to work out the math of how John Dumelo's wife has given birth so soon after marriage.
The obvious answer is that Gifty was pregnant before the couple got married, which actually dovetails with reports from the time of the marriage that John had to marry his wife because he had knocked her up.
On social media Dumelo is being mocked for this fact and the actor has responded to one of these trolls who can't believe John Dumelo's wife can make a baby in only five months.
READ ALSO: "The Money Belongs To Me" – Patapaa Reveals Why He Picked Monies "Sprayed" On Him While Performing
After someone tweeted at him about the issue, Dumelo responded.
According to him, he used the NPP's double track system and that helped him get his baby ahead of time. LOL.
Check out twitter interaction below…
I used double track system… https://t.co/8vQlkZv4za
— MrDumelo (@johndumelo1) October 16, 2018
Source: GhanaCelebrities.Com


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My name is Anna Sweet. I love creating music and learning from history, and it is my desire to share my passion for both music and history with others. I am a member of Lake City Community Church and play on the worship team there regularly. I have a BS in Music Education from Corban University and have previously taught General Music, Orchestra, and Choir at the Elementary Level, as well as teaching private lessons since 2006.
I will be teaching music and social studies at Lakewood Lutheran this year. I am excited to work with the students this year and help them discover their passions


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I have been trying to process through the verbal comments I hear regarding my work. The process has been necessary and helpful.
The most important perspective is that my work is not a performance. There is no planned choreography, no scripts, no calculated outcomes that can be counted on. Of-course there are goals and knowledge based plans of care…but there is NO Performance.
There is a deep need to have a Supernatural Lead as I prepare to meet, walk up to a door, introduce myself and begin to talk through their hospice need. If it were not for that Supernatural Lead, I would be stumbling and hurting people in their time of grief and surrender.
Know I am grateful for that leading and any feedback that comes my way!


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It's fair to say Taylor Swift has had a bad week…
The 'Bad Blood' singer suffered backlash after Kim Kardashian West published a video of her appearing to okay some of the lyrics to Kanye West's 'Famous' - and it's been revealed that she always feared something like this happening.
Taylor told Capital back in 2015 that she's pretty paranoid when it comes to being secretly recorded.
"I have a lot of issues with buildings like this, 'cos I always feel like someone has bugged the room, and is either videoing me or recording me," she admitted.
"So that's one of my paranoias."
Sadly for Taylor, her fears came true, and she posted a Note from her phone on Twitter to try to explain the situation following's Kim K's video - but even then there was an apparent twist in the tale...
Digital Spy's Entertainment Reporter Naomi Gordon recaps the history of Taylor and Kanye's feud with Kimye below:


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The amusing yet revealing story of how a singing competition helped build a new Europe, sequin by sequin.
Read more | Buy DVD
Cracking The Colour CodeJudith2018-08-13T17:16:03+08:00
A lush and visual exploration of how we see colours, how we make them, and the meanings they hold in our world.
Read more | Enquire DVD | Buy VOD


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Holiday Art Collection
Have you ever realized there is pretty much some holiday for EVERY month of the year?! Looking for a simple way to decorate each month? Monthly subway art is the perfect way to celebrate throughout the year.
Choose from a variety of already framed professionally printed subway art prints (13 prints included inside each frame for you to rotate each month) OR purchase a digital download for your favorite months and print your own!


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The grayness all around us appeared as ephemeral, wide wisps of varying chiaroscuro tones, as might fine smoke from a fire composed of a variety of combustible items seem on a clouded night. Darkness prevails, only a dim glow coming from the stuff guides our way. Pressing with force through any section of it leaves…Read More
All articles filed in flash firction
The Crash
Lester sat reading his daily devotional with a steaming mug of black chicory-laced coffee. He heard what sounded like a tree falling across his barn but he knew there was no tree near enough to do that. By the time those thoughts had cleared, he stood in the farm yard looking at the tail end…Read More


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Supreme Ky
Rapper/MC – Grime, Hip-Hop, Rap
Supreme Ky is a South London rapper with a talent like no other. He's a very energetic MC and spits flames every time he gets on the Mic. Ky started his career at the age of 14, now with over 10 years of experience he's become a master of his craft. Whenever Ky gets on stage his passion can be felt by everyone in the audience, he'll never leave a show with disappointed fans. His influences come from genres such as Hip-hop, Reggae, Grime, RnB, Alternative rap and Rock. He's a very versatile artist meaning he's open to experimenting with different genres of music. His early influences have come from listening to So Solid Crew and many other garage artists at the time. This then stemmed into influences such as Biggie Smalls, Nas and Wu Tang Clan. Being exposed to such major artists has made Ky aspire to be one of, if not the biggest rapper in the UK and globally. Some of his biggest achievements are winning "Get Discovered" and performing in front of members from So Solid Crew. Plus, Supreme Ky has aired on the national TV channel London Live and has been featured in the Voice Newspaper for his "Get Discovered" win.


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As EU negotiators have continued to push back the deadline for achieving a draft Brexit treaty this week, Theresa May and her EU counterparts have expressed tentative support for extending the Brexit transition period, the latest "compromise" proposal to crop up during the seemingly interminable negotiations. However, this proposal isn't a solution. As one BBC editor put it, the proposal for a longer transition is "an extension to an extension that's not a request for a longer transition period but a desire perhaps to have the option" at some point in the future, assuming the two sides can even agree on a treaty to create a framework for those negotiations in the first place. Of course, when politicians are facing an intractable problem, they rarely miss a chance to engage in some preemptive can-kicking.
With the March 29 "Brexit Day" drawing ever nearer, and the risk of a "no-deal" Brexit looming ever larger, many who haven't been following every headline about the increasingly fraught negotiations (and even some who have) are struggling to piece together what, exactly, is going on.
Fortunately, the Automatic Earth has created a handy chart to help readers with this. It's called "The Brexit Trilemma". It represents the three promises made by May's government that are in direct contradiction with one another.
With this in mind, it appears May has four options all whof which are politiclal unteneable.
Option A: Break promise to DUP and erect a border in the Irish Sea.
Option B: Break promise to Ireland/EU and impose border checks in Ireland in violation of the Good Friday agreement.
Option C: Stay in single market and customs union, violating promises made to conservative Brexiteers, likely resulting in a leadership challenge.
And Option D: The "unicorn" trade deal - also known as "magical thinking."
These conflicts pertain solely to the so-called Brexit "backstop" agreement, a last-resort measure that would only take effect if the two sides fail to negotiate the final Brexit terms on customs and trade during the transition. Another conflict has arisen over whether the backstop agreement should be time limited or open ended, which recently led one government source to propose that the backstop "can't be limited by a fixed date, but might be capable of limitation by reference to a formula or a test to establish redundancy".
How will @theresa_may reassure Brexit backstop is temporary? Government source: "can't be limited by a fixed date, but might be capable of limitation by reference to a formula or a test to establish redundancy". https://t.co/MRvRhDqiIZ— Robert Peston (@Peston) October 16, 2018
Which provoked the following penetrating comment penetrating comment illustrating the extent to which these negotiations have descended into absurdity.
Oh for fuck's sake. So brexit is now reduced to a woman standing on her head, on the back of a unicorn, being restrained by Ulster Presbyterian flat earthers, in a parallel universe, balancing Fermat's last theorem on her left big toe #clusterfuck— Alan Kirwin #FBPE (@alankirwin) October 16, 2018
Perhaps this is what the EU meant when it chided May to "get creative" in attempting to square these opposing interests?


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The next day Jesus decided to leave for Galilee. Finding Philip, he said to him, "Follow me."
Philip, like Andrew and Peter, was from the town of Bethsaida. Philip found Nathanael and told him, "We have found the one Moses wrote about in the Law, and about whom the prophets also wrote—Jesus of Nazareth, the son of Joseph."
"Nazareth! Can anything good come from there?" Nathanael asked.
"Come and see," said Philip.
Philip was the first one to meet Jesus where John was preaching. He had a brother named Nathanael and he went and told him about Jesus. Nathanael was incredulous at the notion. But then Philip did something wise. He didn't preach at him, lecture him, work to convince him or anything like that. He just said this,
"Come and see."
It's probably the best evangelistic advice still today. Show them Jesus so they can decide for themselves.


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This webcast features: Dr. Fai Poon, President, Quacell Biotech Ltd.
China's biopharma sector faces multiple challenges in quality management, including lack of experience and talent, a rapidly changing regulatory environment, as well as cultural issues in management. In Part 3 of our series Fai Poon, President, QuaCell Biotech, Ltd., will cover China regulatory issues, a review of current challenges in biopharma quality management in China, and opportunities for progress in this field with the growing CMO platforms and the emerging CQO business.
Just fill out the form below to watch the recorded webcast now.


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Richard Butler-Creagh is the founder of Henley Finance which is a short- term bridging finance company. Here is Henley Finance advice about getting your taxes right:
Being an entrepreneur and establishing your own business provides tremendous freedom that you just can't get working for someone else. When tax time arrives, entrepreneurs must take a totally different approach to taxes than the average worker. For example, when you work for someone else, your employer takes care of withholding taxes from your checks. But when you're self-employed, that tax requirement falls only on your shoulders.
Know and calculate your self-employment tax obligations.
As mentioned above, you have to pay self-employment tax if you work for yourself. Part of this tax goes to Social Security and part to government medical insurances. This is in addition to individual income tax. If this is the first year that you're in business for yourself, you'll need to estimate how much money you expect to earn by December 31st. Otherwise, you can use online worksheet programs to help you figure out your tax obligation based on your prior year's tax return.
Seek advice from your accountant
Once per quarter, see to it that you sit down with your accountant, and review several items. First, check to make sure you are setting aside the right percentage of funds in your accounts.
Also take a look at the changes in your business since your last meeting with your accountant. Looks at trends, and discuss the company's status. Finally, know of any changes in tax laws that might affect the way you are currently operating. This meeting doesn't take a lot of time, but make sure you are doing the right things and heading in the right direction. This gives you time to make course corrections before you stray too far.
Know Your Tax Laws
Your accountant is your best, most consistent source of information about important changes to the tax code. But you can't get lazy and expect a third party to do everything for you. If you're an active partner in making sure you're up to date on the tax laws that affect you, you can be better positioned to take advantage of opportunities to reduce your liability and ensure you're not caught short when it's time to write the government a check.
Know Your Tax Deductions
This is another area where it pays to use an accounting service, so talk with certified tax accountants as necessary. While you certainly want to pay all the taxes you owe, there's no sense in paying more than you're legally obligated to. Consult with your accountant to make sure you're positioned to take advantage of the tax breaks you're entitled to. Just make sure you're claiming all of your available deductions; many entrepreneurs don't. While none of us particularly enjoys paying taxes, it's far less painful when you have the funds to cover your obligation. Careful planning and regular checkups can help ensure you're never surprised to see your taxes again.
.Learn more about Richard Butler-Creagh here, Visit Richard Butler-Creagh CrunchBase page here, connect with Richard Butler-Creagh on his Linkedin page here and visit Richard Butler- Creagh website here.


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First, I have some exciting news! My work was published in the latest issue of Crazy Quilter's Quarterly! Isn't that awesome? Sure, it's Viewer's Submissions but I'm published! What?!
I can't believe I'm saying this but I did almost no hand stitching in the months of March and Apirl. I managed to keep up with the Round Robins that I signed up for but that's about all. Carpel tunnel sucks, although I have to admit yoga has really helped so much. This is part of the Batik Me Round Robin. I tried a woven stitch for these Egyptian like flowers. They turned out pretty cool but I'd have to admit that my execution needs some improvement.
I tend to do a lot of paisleys, I know. Can't help it, I love them. I also did the rick rack below it.
This rose ribbon was given to me by a member of the Yahoo Crazy Quilters Group. I was rummaging through my lace box and it fell out on to the block and I just loved the colors with the block! It's almost cheating but not really. It certainly helped with my carpel tunnel, just a quick slip stitch and it was done.
I've lost track of who this block belongs to. I'm pretty sure it was part of the Novice Round Robin that is just finishing up. These pictures are terrrible but you'll get the idea. I did a zigzag chain with bugle beads in the center. Then along this great velvet striped fabric, I did orange stars with green colonial knots in the open area.
Then I added the threaded linked chain leading up to the tatted butterfly that someone else did. It's super wonky but kind of appropriate for a butterfly trail.
And, this is my May Crazy Quilt Journal Project. I love the little duckling but I fear it gets a little lost. I'm still working on keeping things balanced. My ribbon work often over takes the block. We'll have to see what next month brings.
I realize how ridiculous it is that this is me, giving up stitching for prom season... What can I say? I'm a bit crazy.
Thanks for stopping by!
I realize how ridiculous it is that this is me, giving up stitching for prom season... What can I say? I'm a bit crazy.
Thanks for stopping by!


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Members of the Kansas delegation to Congress are working to advance the decorated military career of Bob Dole, the former U.S. senator who was badly wounded as a soldier in World War II.
The U.S. Senate last week passed legislation sponsored by Sen. Pat Roberts and Sen. Jerry Moran that would promote the 95-year-old Russell native from captain to colonel in the Army.
U.S. Rep. Roger Marshall, from Kansas' 1st District, is pushing for the bill to gain traction in the House.
"I am humbled to know that my friends in the Kansas delegation made it a priority to honor me in this way," Dole said. "I was certainly proud to serve in the U.S. Army during World War II -- alongside many heroes who never returned to American soil. To me personally, this legislation is a shared honor."
Dole joined the Army Enlisted Reserve Corps in 1942 and was called to active duty the following year. He was deployed to Italy as an infantry lieutenant in the 10th Mountain Division, and he was wounded in 1945 when German machine gun fire struck him in the upper back and right arm.
Dole was cited for acts of heroism under fire and received two Purple Hearts and the Bronze Star. His injuries left him with numbness in his left arm and limited mobility in his right arm, which he minimized in public by holding a pen in his right hand.
"Bob Dole is an American hero and Kansas' favorite son," Roberts said. "I'm proud my colleagues in the Senate acted quickly to pass this important legislation, which will give Senator Dole the military promotion he has earned during his decades of service to our country."
Dole won election to the Kansas Legislature in 1950 and became the Russell County attorney two years later. He represented Kansas in the U.S. House from 1961-1969, then spent the next 27 years in the U.S. Senate. He stepped down in 1996, when he became the Republican nominee for president.
In Congress, he cosponsored bills to improve veterans benefits, improve accountability for missing members of the Armed Forces and recognize women veterans, among other initiatives.
"I can think of no one more worthy of an honorary promotion to the rank of colonel in the United States Army than Senator Bob Dole, who has for decades served our country with the utmost distinction," Moran said. "From his time in the military and in Congress, to his continued leadership on veterans, hunger and disability issues, he is a true model of public service for Kansans and all Americans."
Marshall's staff is working with the House Armed Services Committee to advance the honorary promotion and has asked House leadership to bring the bill forward.
"It was really good to see the Senate take swift action on this," Marshall said. "I cannot think of anyone more deserving of this honorary promotion than Kansas' finest, Senator Dole. I now call on the House to honor his exemplary service and sacrifices to this country and pass this legislation."
Last year, Dole received the Congressional Gold Medal as President Donald Trump hailed his "extraordinary life." In September, Washburn University unveiled a bronze statue of Dole on campus. In November, he was inducted into the Russell County Hall of Fame.
In a poignant moment in December, he saluted former President George H.W. Bush as his casket was displayed in the Capitol Rotunda.
"Bob Dole's legacy of valor in combat and lifelong career of selfless service to the nation represents the highest ideals and values of the Army as well as the Greatest Generation," said Gen. Mark Milley, the Army chief of staff.
This article is written by Sherman Smith from The Topeka Capital-Journal and was legally licensed via the Tribune Content Agency through the NewsCred publisher network. Please direct all licensing questions to firstname.lastname@example.com.