text:
Chicago International Film Festival, Clemency, Comedy, Drama, Ford v Ferrari, Jojo Rabbit, Les Miserables, Lists and Insight, Parasite, Waves
This past weekend, I attended the Chicago International Film Festival at the AMC River East 21 in Illinois. Anyone that knows me knows that covering the fall festivals and awards circuit has been an aspiration of mine for years, and I was excited to attend this event and check out some of the fall's hottest titles. Due to time and budget constraints I wasn't able to see everything I wanted to see, but I saw a good number of films that I think will be interesting to read about, and will be discussed at length in the next few months.
First, I'd like to extend my thanks to the many volunteers and event coordinator involved in this year's films. This was a packed event filled with Q&As, screenings, and workshops, but I was able to find my way to each screening with relative ease. This was a well-organized event that I would recommend to any cinema lover who has the opportunity to attend.
This weekend, I saw six films. Five of them- Ford v Ferrari, Jojo Rabbit, Clemency, Les Miserables, and Waves were screened as part of the festival, and while I was in Chicago I also saw the acclaimed Bong Joon-ho film Parasite, which despite receiving universal acclaim has yet to screen anywhere else in the U.S. outside of the coastal cities. Below are brief reviews for all the films I saw.
Ford v Ferrari comes from director James Mangold, who has quietly become one of the world's foremost providers of adult drama- from biopics (Girl, Interrupted, Kate & Leopold, Walk the Line) to more mature action pieces (Cop Land, 3:10 to Yuma, Logan), Mangold makes films that feel synonymous with unabashed Golden Era showmanship. In his films, actors aren't just giving performances, they're being movie stars, having conversations that only movie stars could have, and with frequently rising runtimes, Mangold usually packs a whole lot of movie into each project.
This isn't to say that Mangold's work is retrograde- the technical wizardry alone is an argument for the singular nature of the cinematic experience. Ford v Ferrari isn't just long, it's also loud, with screeching tires and internal engine combustions shaking the seats with bombastic energy. Mangold is a stickler for process; with 150 minutes, he's clear to make his depiction of cars detailed, putting us behind the wheel and in the pit with the lead characters. The dialogue is precise and doesn't simplify; even if I wasn't sure what the characters were referring to, I was always sure that the actors did.
Based on a true story, the film follows two unlikely partners: car designer Caroll Shelby (Matt Damon) is waxing poetic about his former life as a racer, and Ken Miles (Christian Bale), is an eccentric racer whose caustic attitude has made him a tough bet for potential sponsors. As Ferrari dominates the racing landscape, Henry Ford II (Tracy Letts) enlists the pair to build a car that will guarantee a victory at the 1966 24 Hours of Le Mans, with Miles as the driver.
Sure enough, the film opens with a big race that sets the stage for Shelby's former life as a driver with an outlaw spirit, and quickly enough juxtaposes his menial day job. It's an easy tone setter, as we need to see the scale the film's operating at early on, but it's also a good way to show the type of restraint Mangold has. We start with a big race and use another small race to introduce Miles, and while there are intermittent races throughout as Shelby and Miles test their vehicle, for the most part the excitement is saved for the end. It's a way of not showing the cards too early, but also keeping the audience in on the effort. When Le Mans starts we know the interior and mechanics of the titular Ford by heart, yet we're still able to be blown away by the sheer ferocity of this epic race played out in full for the first time.
What makes Le Mans different within the racing world is that it's a day long race- the type of mistakes that wouldn't derail a shorter lap have time to manifest as the tired drivers and their teams rally around for a day long slog. It's fittingly a long sequence, but there's very little fat to it; at the end of the day, Shelby and Miles are problem solvers, and the lengths they go to perfect their craft and maneuver corporate politics are more interesting than just watching two cars edge past each other for a full day.
Bale is unquestionably the standout performance; he's a wild guy with an unmatched mastery of his field, and a scene as simple as Miles correcting a customer on how his vehicle should be driven wouldn't work if Bale's "No, I'm right" insistence wasn't backed up by a clear understanding that his ego is justified. Scenes with Miles's family are the ones that slow the film down the most, as they're mostly thankless and aren't particularly well developed, but the relationship between Miles and his son (a great Noah Jupe) do a good job at showing how strong the familial bond is. Miles is a guy we're inherently rooting for, but being a hero in his child's eye is just the right way to put a human behind the wheel.
Damon is also quite good here (as he almost always is); the film is smartly bookended with scenes of him behind the wheel, and although Miles is the one with the winning lap, it's clear that Shelby is very much equally in control. Damon can play the smartass and he can play the hapless hero, and this role gives him a chance to be both, as a cunning business type who plays Henry Ford for a shot at Le Mans and also a straight man to the more eccentric Miles. A final round of tie ups for the Shelby character gave an unexpected weight that I wasn't expecting, and no one is able to sell the idea that they love what they do quite like Matt Damon.
Ford v Ferrari has solid craftsmanship from everyone involved, and to say that it left me exhausted is not a bad thing. The racing scenes enough should be worth the price of admission, but it's also a testament to how a big-budget studio drama film should feel. Maybe you learn something, maybe you feel inspired, but this certainly isn't one that I expect will bore. Grade: B+
Based on my (somewhat) limited understanding, the overarching theme in South Korean cinema at the moment is the contrast between the haves and the have nots. Of course, this is a theme that holds weight in all corners of the world, but the particularly sharp class divide occurring now in South Korea has certainly inspired some of the world's most talented filmmakers to skewer privilege and wealth- Bong Joon-ho has actually done this several times previously, with Okja and Snowpiercer being two recent examples.
To put it bluntly, I've never seen a film tackle the bliss and yearning on each side of the wealth gap as well as Parasite. Often times satire comes from living out a fantasy that would otherwise seem implausible, but Parasite isn't trying to be cathartic. There's a gleeful joy in seeing Bong lay out the blunt reality of elitism, but as the story unravels it's hard to not laugh and cringe in equal manner. Throw a slew of great performances on this decadent balancing act and you have what I think is now unquestionably a modern classic.
Parasite is about the relationship between two families; the Kims live nearly underground, use a neighbor's wi-fi, and hustle for gigs that include boxing pizzas, while the Parks take residency in a slick mansion where their two children are groomed for success by expensive tutors. The Kim's son Ki-woo has recently left military service and through a friend finds himself the English tutor for the Park's teenage daughter Da-hye, despite having no qualifications. What starts off as a simple con becomes a means for the Kim clan to feed off of their wealthy counterparts, colliding these two families forever in a twisted confluence of lies and deceit.
It's beyond entertaining to see the Kims in action; this is a tight family unit that operates like the Ocean's Eleven crew, and they need to do so in order to survive. The skills they pick up aren't ones that seem super complex, but it's evident how these basic means of survival could be completely alien to the Parks, who live in a literal mansion that feeds off of their wildest desires. It's a gradual infiltration spearheaded by Ki-woo's initial deceit, and once the Kims understand that for the rich money is always a solution, it becomes a tight rope act as to when and how things will go awry.
I want to say as little as possible about the main plot of the film, but I'll say the second act (which is initiated with a reveal that inspired literal gasps from my audience) is some of the most suspenseful, confidently staged filmmaking I've ever seen. Bong and his team designed the Park mansion from scratch, and behind each luxury is the potential for a moment of suspense or conflict. The way in which characters are positioned- which room they're in at a particular moment and the individual steps that must be taken to get out of that environment, are transitioned with such magnetic grace that it plays out like a manic choreographed dance. It's easy to say "Hitchcockian," but Bong is so clearly someone who makes his environments products of his narratives in a manner reminiscent of Rear Window or Vertigo.
The Parks aren't nice rich people, Kim matriarch Chung-sook remarks at one point, but "they're nice because they're rich." The Kims' ignorance is often comical, but Bong never forgets the ramifications of what they have. It's really funny that this wealthy family hires an expensive art tutor to interpret their young son's abstract drawings, but it's less funny when there are people living below the streets whose very livelihood could be gone in an instant due to a natural disaster. The Kims never turn out to be mustache twirling maniacs with wicked intentions, and it's the normalization of their gross subjugation of the lower class that is almost scarier.
Parasite goes to many unexpected places, but never stretches believability beyond the truth of what we see these families are capable of. A film so hell bent on surprising its audience needs to have payoffs for each shock, and thankfully Parasite ends on the perfect note that signifies how this cycle could begin again. Dastardly funny and deviously thrilling, this is a film that could easily be rewatched to soak in all its meaning, but I doubt anything will top the pure visceral shock of its first viewing. Grade: A+
Taika Waititi's latest venture Jojo Rabbit is perhaps not being marketed as what it is: a family movie. It's a film that takes a look at life under the Nazi regime from a child's eyes, and all the stakes and sorrow found in that era is seen from the perspective of someone who is naïve and susceptible. The film itself isn't that naïve; the stakes are all real and they are felt, but the means with which it copes with these issues is geared towards a young audience and intended to both educate and entertain them in a PG-13 manner.
Jojo (Roman Griffin Davis) is a ten-year-old boy living in Germany during 1945, and despite not being the strongest or most bloodthirsty of his generation, he's found inspiration in his imaginary friend Adolf Hitler (Taika Waititi). Jojo wants to serve his country and makes his family proud, but his world is turned upside down when his mother (Scarlett Johansson) fosters a runaway Jewish girl (Thomasin McKenzie) in their attic.
While the "imaginary Hitler" subplot is by far the most talked about element of the film, the character only shows up momentarily throughout the film in order to urge Jojo's worst impulses. Waititi is clearly having a blast with his sendup of Hitler, and is able to confront his persona by depicting him as a blithering idiot, all while occasionally being genuinely scary. This is an important line that Waititi has to walk, both as an actor and a writer/director; it's important to show that Nazis are stupid, and the best way to do that is through humor, but he also has to communicate the irreparable damage that hateful ideology has.
I think Waititi succeeds in this regard; while there are moments that simplify the Nazi movement (at one point comparing the rise of Nazism to Beatles mania), the film revolves around Jojo's inability to grasp the gravity of the situation. To Jojo, the Nazis are the older kids at school who he needs acceptance from, and try as he might, Jojo is not a hateful person and will never belong. His mother tries to protect him and teach him, but when hate is so engrained within a culture it's hard to show another path.
The empathy within Jojo comes from his relationship with Thomasin McKenzie's character, and again it's a tricky one that Waititi pulls off. At first there's a hesitation, and obviously Jojo grows infatuated with this older girl, but in the end both characters have lost family, and as a result don't know their purpose. The joy of these two interacting doesn't downplay the terrors surrounding them; in fact it's an antithesis.
With all this being said, I have to give a massive amount of credit to Roman Griffin Davis, who gives one of the most impressive child performances I think I've ever seen. Jojo is a kid whose forced to be an adult, and the harsh juxtaposition of childlike energy and priorities with one of the darkest periods in human history requires Davis to grow from blissful irreverence to crushing self-awareness. He's a silly kid who has funny conversations with imaginary Hitler, and there's tons of great physical comedy (which gets fairly brutal at points), but there's images of a child growing up in a warzone that remain haunting.
Davis is also working with a tremendous ensemble; Waititi is uproarious and McKenize has to channel a slightly older, yet still innocent sense of adolescent charm. Many of the film's strongest moments come from Jojo's relationship with his mother. Johansson is simply wonderful; we get the sense that she's unsure of how to present the world to Jojo, and behind the façade of being a struct, playful mother is a determined person who deeply believes in the power of compassion. I'm sure there will be controversy surrounding Sam Rockwell's depiction of a Nazi officer who trains Jojo and the other boys, but I found the subtle reasoning behind his character's motivations to be inspired, and even thoughtful at points.
Behind the surface of Jojo Rabbit are many things that are left unsaid; many character arcs are relying on only what Jojo sees, and often what's left unsaid or implied is just as potent as the story that's visualized. This is a heartwarming story that doesn't pander, taking risks with how it depicts real issues whilst also speaking to universal truths. Take your kids to see the "imaginary Hitler" movie, please. Grade: A
Clemency is a very rough watch; it's a film that both begins and ends with an execution, and the surrounding conversations are not any easier to get through. In her post-screening Q&A, writer/director Chinonye Chukwu details the hours of interviews, research, and moral deep diving that it took to create this film, and none of the material makes for an easy sit. While the subject matter is certainly loaded, it asks the immortal questions: how can we convict someone without 100% certainty, and what makes legalized killing any more justified?
Tracking the relationship between a long standing prison warden Bernadine Williams (Alfre Woodard) and a prisoner (Aldis Hodge) on death row that proclaims his innocence, Clemency follows the process of someone's journey to lethal injection. The brilliance of the Alfre Woodard character is that things happen around her, but she's not a passive person. We see in detail the impact that duty has upon her, and how her unflinching commitment is unlikely to be understood by anyone else.
A majority of the film takes place in the prison itself, with the few snippets of media information or trips to Williams's home offering a small window into the outside world. There's not an awful lot of movement to the sequencing either; while the occasional nightmare sequences help to visualize Williams's vivid nightmares of the fateful execution table, the film is mostly shot with an uncomfortable stillness. Even the scenes with Williams's husband, played excellently by Wendall Pierce, offer no sense of comfort, as she's still stuck reliving all the lives she's seen taken in the name of the law.
It's important that the details of the case are never spelled out all the way; if there's legitimate doubt, why should it matter? Aldis Hodge is extraordinary in the role, and is able to be vulnerable in a very honest way. Not every scene can be a big emotional crying scene or outburst, and the points in which he has to placate himself and is forced to ignore the injustice are often the most potent in their bitter realism.
Clemency certainly will leave an impact, and both leads do tremendous work in making us understand their suffering. Still, it's the somber removal from anything that should feel normal that makes the film both rewarding and grueling- I have no idea how this story would be told any other way, and its uncomfortable by its very nature. Even though the film is clearly here to tell a message, it doesn't lose sight of the character story its telling; although it feels like there is no humanity in this practice, Clemency finds solace in the fact that we can have this conversation. Grade: B-
Les Misérables is not a musical, nor is it an adaptation of any specific character or storyline from Victor Hugo's legendary source material. Rather, it lifts the themes of injustice, solace, and unity of a movement that are found in the legendary text and places it within the context of modern day France, inspired by real riots in 2005. Showing a day within the life of a city cop who joins an elite squad to stop potential conflicts between ethnic groups on a hot summer day, Les Miserables gets up close and personal with the sparks that can light a city aflame.
Perhaps this was intended to be Les Misérables from Javert's perspective, but in the end I think the film concludes that there's a bit of Jean Valjean in everyone (this is implied though, the references to that story are minimal). The parallels are interesting, as it's also a story that shows the rise of a movement in response to police brutality, how victims become conquerors, and how someone's true colors are shown in the most inconvenient of times. These are the themes of Les Miserables, but it's a story for today.
Damien Bonnard gives a phenomenal performance as Stephane, the film's lead cop who is roped into a cycle of brutality that makes way for violence and uprising. Bonnard is good at making Stephane conflicted; like Javert, his loyalty is to the law, but when his colleagues take advantage of their power, where do his loyalties lie? Stephane isn't a bad guy, but he's part of the problem, and whether or not he's part of the solution is up to the viewer's interpretation of the final frames.
Director Ladj Ly leaves quite an impressive feature, with many intense chase sequences throughout the cluttered city streets. We don't need to see every corner of the city to convey its magnitude, nor do we need to see every face in order to depict the different sensibilities that are going around at any moment. It's a race against time for the cops to solve a dispute, and the film balances it's actual driving force with the audience's knowledge that under these circumstances something is bound to go wrong, and we should expect something horrific.
The final set piece of this film is genuinely brilliant, a chaotic frenzy in which the simmering conflicts between every player burst to the surface and emerge within one confined, claustrophobic building. It's a sequence in which we're caught begging for de-escalation, but we couldn't even begin to think of a way how. Perhaps this is the barricade moment for this Les Misérables; if the most interesting part is how we move on from the barricade, than this film is about the moments before the fallout. Grade: B
"Emotionally overwhelming" is a good way to start talking about Waves, but I'm not sure that any words I have would do justice to the wide range of feelings one may have experiencing this film. It's too overreaching to say that Waves is about everything, but there's so much to say about the film's approach to love, loss, and healing; this is a film that begins as a slow indoctrination into a specific family culture, rises up to be an intense climax of unchecked anxieties, then leaves us with a cathartic series of healing.
The story of Waves isn't as remarkable as the way writer/director Trey Edward Shults chooses to tell it; it's a clearly bifurcated structure, made to be off putting to the point that different aspect ratios are used, and the frantic motion of the first half gives way to a still beauty in the second half. The question is, does it work? Unquestionably, yes. Shults understands that trauma in itself isn't worth depicting unless it can be understood, realized, and ultimately confronted.
The Williams family live in the seemingly perfect world of suburban Florida. Ronald (Sterling K. Brown) is a patriarch who challenges his son Tyler (Kelvin Harrison Jr.) to go above and beyond in every aspect of life, as his daughter Emily (Taylor Russell) struggles to find love and live within the shadow of her brother. This is a family unit that is immediately understood; they go to church together and show up for each other's school events, but there's a point where love becomes more about duty than it does compassion, and that's the ambiguity that Waves is examining.
Is Ronald a bad father? Perhaps, but he isn't meant to be the antagonist. If Ronald's motivation for pushing Tyler to be the best is to show him the privileges he has, then are his expectations justified? Ronald isn't able to convey the unconditionality of his love, and for Tyler it's a crushing pressure that pushes him beyond reasonable expectations. Tyler can't confide in his father if he's worried about facing disappointment, and the result is a family that are all left wrapped up in their own thoughts and unable to communicate with one another.
On the other side is Emily, who is underseen in her family's eyes. When Emily finally finds someone worth spending her time loving in the nerdy boy Luke (Lucas Hedges), it's in the wake of events that have caused her family to splinter apart. She isn't able to forgive people that can't apologize to her, and the empty shadow that her family casts upon her forces her to confront dysfunction that is often left unsaid.
What Shults does visually with this film is unprecedented; with his relentlessly energetic pans, including many impressive 360 angles and tracking shots of the kids' everyday school days, Shults has utilized the cinema verite theories into something that is grimly realistic while also artful. It's said that many films look like paintings, but Shults is really able to cascade color off of his panoramic that feel like a distant, yet vivid memory. Often the film relies on the strength of the expressions of a human face, not dialogue, and the uncomfortable close ups Shults captures are works of art in of themselves.
Waves is a film that will take a toll on its viewer; while its structure is meant to be cathartic, the solutions it offers for coping with tragedy aren't always the easiest to swallow. I do think it's an essential viewing experience, and regardless of your own family dynamic, I think there's truth in everything Waves puts forward. In his post-screening Q&Q, Shults detailed that much of the film was autobiographical, and I can't think of any way this film doesn't come off as anything less than completely authentic. Grade: A


text:
Megan Mullally, who played Karen Walker payed tribute to the hilarious woman who portrayed her maid on the hugely successful show.
'Just got a bulletin on my phone that shelley morrison has passed,' she wrote.
'Putting shelley, her beloved husband walter & their children in the light. thank you for your friendship & partnership, shell. you accomplished wonderful things in this world. you will be missed.'
Debra Messing added, 'Oh, Shelley… what a loss. Our dear Rosario has passed on. Shelley had a career that spanned decades, but she will always be our dear Rosie. All my love to Walter and the entire family. #shelleymorrison 😢.'
Eric McCormack, who played Will to Debra's Grace, took to Twitter to pay his respects to the comedienne.
'Shelley was a beautiful soul & a wonderful actor. Her work as Rosario, season after season, was as nuanced and real as it was hysterical. She will be missed by everyone at #WillandGrace, she's a huge part of it. Sending so much love to Walter and Shelley's whole family. #Rosario,' he wrote.

subset: commoncrawl


text:
Function: Design/Fabrication/Repair
Department: Center for Solid State Electronics Research
College/Unit: IRA A. FULTON SCHOOLS OF ENGINEERING
Description:The Center provides resources and infrastructure for research and education in solid state electronics in the form of 30 laboratories covering more than 30,000 sq.ft.; including a Class-100 Cleanroom administered and maintained by a complement of 10 staff and 2 student workers.
Link to More Details:


text:
Friday, May 11, 2018
19 comments:
She may be fine off screen....but good riddance to the Vixen. Who needs all the glum vibes and negative energy.ReplyDelete
I,AGREE.....Kameron and Eureka were both stunning, and Eureka was really the only one to have a comedy side to her Cher.
Great recap, as always xoxoxoReplyDelete
WHY do I keep forgetting to watch? The Cher tribute would've been a complete hoot! Well, when will they pay tribute to that other 6-decade gay icon, Babs? I mean, come on....ReplyDelete
Last nightshade was much more entertaining. I see a top three of eureka,Aquaria and mix. I love Kameron, but I don't know she will win.ReplyDelete
Was back home last week & watched the Snatch Game episode with my 82 year old mother. She read Vixen for filth. Got home late last night, forgetting Ru was on (I know, I know, what wrong with me? Don't ask.) I will enjoy the episode more knowing vixen's gone AND I love Groove is in the Heart!ReplyDelete
I still can't believe Mix Cracker hadn't won a challenge yet....but glad Vixen gone.ReplyDelete
The Billy Eichner had me lol!!!!! Your so bad, but that's why we loved you.ReplyDelete
Kameron was the best Cher performer and singer! I also loved Monet X Change! She just radiated Cher's spirit and fierceness! Miz Cracker had the best look! What a stunner! It was my fave outfit of the night. Seriously, why hasn't she won a challenge yet? She was the best in the space/future challenge!ReplyDelete
Aquaria looked fantastic in the runway, too. Now I know where Madonna and Rihanna stole their Met Gala looks, from RuPaul's Drag Race!!! (See Dolores Delargo Towers' latest post in the side bar)...
Glad that the Vixen is gone, because in the end, the best performer won the lip sync. Asia wasn't clowning around! But I am grateful for Asia for stepping out to share some insight with Vixen, allowing us to understand both people better.
We are reminded that these characters are real people, who experience real problems, including class and racial inequalities, loss, and struggling to find yourself and a place to belong, a home.
I'm ready for a big girl win.ReplyDelete
Can't believe I'm saying this… but Kameron is quickly becoming my favorite! And yeah, something sexy about Billy EichnerReplyDelete
Miz Cracker should have been top 3, for some reason I feel Ru and the judges don't like her at all.ReplyDelete
'm actually kind of laughing to myself. Probably a month or two before this season began, I was talking with a friend and I said how shocked I was that "Groove is in the Heart" had never been used as a lip sync song.ReplyDelete
I'm so glad Vixen is gone with her bad attitude and atrocious hair...BYE GIRLReplyDelete
Yes, the Vixen had already set up her own shashsay away weeks ago with her behavior. Agreed with your entire POV on last night's episode.ReplyDelete
When I go to a drag show, Eureka is what I look for. She just glows on the main stage.
I finally saw the episode. It puzzles me the Vixen attacked Eureka and some others on a weak Cher. Ru didn't say you had to sing like Patty Lupone. They did what they were asked to do, and came through. As bad as Kameron was during rehearsal, he really did capture Cher's essence, as did Eureka with her looks and a few sound bites. Vixen and Asia were the right two be put up.ReplyDelete


text:
Immune Responses in Cancer
It is increasingly recognized that various types of immune cells play important roles in protecting humans from cancer. Dendritic cells (DCs), in particular, occupy a critical position in regulating immune responses, as they have the potential to translate signals issuing from innate immune cells into productive adaptive immune responses. Upon direct contact with DCs, naïve CD4+ T cells and CD8+ T cells can undergo differentiation into specific T cell subsets. These different types of effector T cells are specialized to destroy tumor cells and to protect the host against invading pathogens.
Regulatory T cells are crucial for maintaining self-tolerance, and they can suppress effector T cell functions and block antitumor-immunity. Because immature DCs promote the generation of regulatory T cells, whereas activated/mature DCs can launch the differentiation of naïve T cells into effector T cells, DCs are critically involved in balancing regulatory versus effector T cell functions.
Our current research focuses on the molecular mechanisms that govern the transition of DCs from the immature state to the mature state. We investigate the process of DC-maturation and the mechanisms that counteract this process. By using a combination of immunological and molecular biological methods, we analyze the state of DC maturation and investigate the properties of those cells to determine the outcome of the respective T cell responses.
Maier E., Mittermaier M., Ess S., Neuper T., Schmiedlechner A., Duschl A., Horejs-Hoeck J. Prerequisites for functional Interleukin 31 Signaling and Feedback Regulation by Suppressors of Cytokine Signaling (SOCS), 2015, J Biol Chem. Oct 9;290(41):24747-59. doi: 10.1074/jbc.M115.661306
Maier E., Werner D., Duschl A, Bohle B., Horejs-Hoeck J. Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way. 2014, J Immunol. Jul 15;193(2):645-54. doi: 10.4049/jimmunol.1301836.
Schwarz H, Posselt G, Wurm P, Ulbing M, Duschl A, Horejs-Hoeck J. TLR8 and NOD signaling synergistically induce the production of IL-1β and IL-23 in monocyte-derived DCs and enhance the expression of the feedback inhibitor SOCS2. 2013. Immunobiology. Apr;218(4):533 42. doi:10.1016/j.imbio.2012.06.007
Posselt G, Schwarz H, Duschl A, Horejs-Hoeck J. Suppressor of Cytokine Signalling 2 (SOCS2) is a feedback inhibitor of TLR induced activation in monocyte derived dendritic cells. 2011. J. Immunol., 187:2875-84. doi: 10.4049/jimmunol.1101044
Maier E, Hebenstreit D, Posselt G, Hammerl P, Duschl A, Horejs-Hoeck J. Inhibition of suppressive T Cell Factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling. 2010 J. Biol. Chem. 286:919-928. doi: 10.1074/jbc.M110.
Jutta Horejs-Hoeck, PhD
Associate Professor
Department of Biosciences
University of Salzburg
Dendritic cells (DCs) determine the outcome of T cell responses
The conversion of an immature DC into a mature DC is promoted by (micro)environmental factors such as danger-associated patterns (DAMPS), pathogen-associated patterns (PAMPs) and cytokines, which are recognized by the immature DC via the respective receptors (Toll-Like Receptors, Nod-Like Receptors and cytokine receptors). Upon maturation, DCs express a number of costimulatory molecules, including MHCI and MHCII, CD80/CD86, CD40, PDL-1, PDL-2, that contribute to the differentiation of cytotoxic T cells (CTL) or specific T helper cell subsets (TH1, TH2, TH9, TH17 TH22, Treg). Functional responses of effector T cells can be repressed by regulatory T cells (Treg).


text:
Supply Only Fortex Cladding
Fortex is a renowned range of cladding products that can provide low maintenance benefits from using PVC. We provide a wide range of Fortex cladding for trade and supply only in a wide range of effects and finishes. The Fortex cladding range is a popular choice for those seeking a unique textured wood effect appearance with the additional benefit of quick installation. Fortex cladding comes with a wide range of trims and accessories to ensure a neat and professional installation. The product comes in a wide range of beautiful colours including white, pale gold and sand. If you are looking for Fortex cladding, give us a call on 01744 758 881 or email email@example.com and a member of the team will be happy to assist you.


text:
The short answer is "No" except in Western Australia where they changed the regulations for just laser recently.
Our students are relieved when they learn this as they say that they have no interest in makeup, eyelashes, waxing or nails and want to be confident and competent in using energy-based devices for hair removal, tattoo removal, pigmentation, capillaries and skin resurfacing and rejuvenation.
The AS/NZS 4173:2018 Safe Use of Lasers and Intense Light Sources in Health Care expect that anyone who engages with or uses Laser or ILS equipment be trained in safe use of the laser or ISL equipment.
Personnel expected to receive training include:
The minimum certification required is available with us. To enrol please click here.


text:
The final page of chapter 2, it's been a long and bumpy road but we've made it! It seems Chris has new orders, involving Diego and Aria. How will our heroes handle this new threat? Stay tuned to find out!
We want to thank everyone for sticking with us through thick and thin. We will be continuing on with chapter 3, we hope that you guys enjoyed chapter 2 and will continue reading, things are about to really open up as the story moves into the next chapter!
Please consider supporting us on Patreon for access to exclusive high res and uncensored artwork, early sketches, access to pages early, etc!


text:
We first featured Katherine Massey, known as the Honest Blogger on our website on December 3,2018. Here's what we said about her at the time of her feature:
Katherine Massey is also known as "The Honest Blogger", with her no filter approach to life as she talks openly about her mission to end the stigma around mental health.She is the founder of Flintshire Housewives(FHW), a supportive community group with a charitable aim which supports local women and promotes open discussion around day to day struggles, as part of her mission to encourage others to lead their best life, no matter what their past or background.
Recently, we had the honor of reading Katherine's latest project, Living With Dolls: A story of Love, Mental Illness and Freedom. Our book review for Katherine's book is actually being completed by Zoe Monee, a blogger and makeup artist who spends the majority of her time with her face in books.
Take a moment to read Zoe's review below:
"Living with Dolls" is a book that keeps you drawn by suspense, but it does not fail to educate you on mental health. I literally had my strawberries and my Teddy Grahams in my lap as a sat and read the book biting my nails until I realized I literally read the book in one day. I believe Katherine Massey is indeed a gifted writer and God himself guided her pen to paper for this book it's breathtaking and inspirational to read. At the beginning of the book, she talks about her experience with her high school crush which every girl in the world has experienced. While reading this I jumped back in time with her and I have noticed her writing style taps into your imagination and puts her memories in your head like a movie.
One thing I would like to point out is that Katherine keeps the book interesting by telling her story and explaining it in ways we can relate to it. I like how in the start she gives a smooth intro into her abuse, for people that have never been around abuse or have experienced abuse you won't get overwhelmed by the extent of abuse and her home life. Instead of talking to the reader as if we already know her story she baby feeds her life to you and gives you a lot of background information for you to be able to understand her reasoning behind Katherine. I like to think of the way she tells her perspective as a path into her mind if you will. As she talks about her and her husband when they grew up it sends warmth into my heart that young true love does indeed exist.
I am a bookworm, so I am always head first into books but for those who do not like books as much as me, Katherine reels you in through her use of emotion in the way she writes.
Reading this book, I can absolutely say I felt every emotion she portrayed in this book. The suspense throughout this book is better than any Lifetime movie ever created! For example, when she talks about her and her husband and how they began to fall in love with each other, Craig essentially fell in love with her lies, which kept me on the edge of my seat. I wanted to jump through the book to see when Craig found out that everything she told him was lies how would he react to it, but she allows you to see her perspective of her lying to everyone by explaining that not only was it a surviving mechanism but she was protecting him from her real life and not the fairytale life that she let everyone believe.
I was heartbroken when Katherine stated that her eldest brother and sister had been sexually abused by their biological parents. I actually cried when she explained how her siblings called her the untouched child or the golden child but they didn't know that when they all moved out she was sexually abused by their mother as well. I absolutely could not put this book down. The fact that she was sexually abused at night and then the next morning her mom had self-harmed to the point of being wounded and very very weak. As I began to read on through the book I got angry not at Katherine but with her mother and the torture that her mother had put Katherine through. The fact that her mom instead of teaching Katherine about her periods, Katherine's mom used her own period to further take advantage of Katherine. I even got to the point when I wanted to jump into the book and back in time and just hurt Katherines' mom's second taxi boyfriend, not only did he sexually abuse Katherine but he had a second family with 3 kids and he was very perverted which means he sexually was attracted to little kids, I was absolutely SICKENED.
Her story begins to look up as her mother willingly goes into the mental hospital to get the help she always needed. I was excited to know that mental health was advancing and her mother got shock therapy. Though she lost some of her memory, I was happy that Katherine got the mom she always needed. I absolutely could not stop laughing when her mom comes home and sees the life-size dolls that she made during one of her manic states and she was absolutely mortified and quickly put them in the attic. I was also happy that she had Craig. I am honestly Katherines BIGGEST FAN and she has inspired me by pursuing her acting while having issues with mental health and I got affirmation by her getting the part, I can say that I am proud of Katherine for being able to overcome and tell her story. Katherine is such a very talented writer and I absolutely cannot wait to get my hands on the next book that she writes.
Living With Dolls: A story of Love, Mental Illness and Freedom is available on Amazon
Click here for more of Zoe Monee's book reviews


text:
Best Ways to Remodel a Condo and How to Hire the Experts for the Job
Condo remodeling constitutes a specific interior house design that most people have been adopting in current home. The beauty and luxury that condo remodeling comes with makes many opt for it as the best. Residential condos are usually constructed as apartments only that the number of detached condos are increased. The homes look like they are for single families but the yards, building exteriors, and streets are jointly owned and maintained by an association in the community.
Building and selling individual and multi-family residences is what residential construction is all about. It's market involves the single-unit, manufactured, duplex, quad-plex, and apartments. Manufactured housing further involves mobile homes and pre-built houses. The business puts into consideration the size and scale of the operations. In short, a builder buys some piece of land, develops the land by clearing and grading it, and finally constructs roads, drainages, waste removals, sidewalks, water supplies and electrical. The builder will therefore decide on the kind of home to have depending on the market that receives his services. One are two houses may be built with the sole intention that once they are finished, someone will always be there to buy them and therefore the constructor does this prior to sales.
It is more cheap and affordable to have a well-planned home than doing the work of remodeling all over again. Improving the value that a home has is what is called home addition. For less costly services of home addition, investing well on the materials and purchasing quality materials is the way to go. The results of home addition will be superb having enough space and also improvement on the appearance of the home.
Discovering The Truth About Remodels
In Clearwater home addition is far much better than buying a new home all together. Adding home extension are less stressful than having to move out into a new place. Clearwater home addition have the best options for those who do not love moving into new places or even sell their homes for better ones.
Remodels Tips for The Average Joe
At Clearwater condo remodeling offers the best services to their clients such that they will be contented with the project that they began. Finally, the upgrading of the home will be commenced and ended in time .
Clearwater Residential Pty Limited, have services such as designing, development and construction specialists. It is a more trusted constructer by both its clients and suppliers due to the services it offers.


text: Do you want a fun, interactive and motivational speaker who can help your audience discover unlimited levels of confidence in their lives? Confidence is the foundational principle to lasting success, and Chad Coe can connect with each person in the room to help them discover their hidden talents, self-esteem, and the confidence that is needed to break free of limiting beliefs. This 7-step process provides the audience with actionable tools that can be applied immediately. Chad teaches people to overcome obstacles, make a positive impact in the world, and step forward in leadership roles. By applying these principles in his own life, he was able to build a highly profitable financial services enterprise. Now he teaches these techniques in his leadership keynote to encourage people to find higher levels of success through improved self-confidence.


text:
Home > Ride-On / Tractor Mowers
An exceptionally manoeuvrable ride-on.
The Cub Cadet XT2 PS117 is part of their Enduro Series, and benefits from a powerful and reliable Kawasaki engine.
Market-leading agility
Despite this machine having a large cutting width, it retains the 17 cm turning circle that marks Cub Cadet's XT2 range out from the competition. This allows you to comfortably navigate around obstacles and lawn furniture without leaving huge swathes of grass remaining to be cut afterwards. Thanks to the RevTek system, the XT2 PS117 is able to cut in both forwards and reverse, allowing for exceptionally intuitive control.
Reliable power & performance
With Kawasaki's strong V-Twin 603cc engine inside it, the XT2 PS117 has the power to consistently get the job done. When combined with the 46 inch / 117 cm cutting width, this model is able to enjoy a mowing capacity of 9,000 m2 per hour through its side discharge channel. To achieve the best finish for your lawn, a choice of twelve cutting heights is provided, between 25 mm and 100 mm. You also have the added benefit of an included mulching kit to give extra cutting versatility.
A fantastic machine to work with
Soft touch cruise control and hydrostatic transmission mean this ride-on will take all the strain as you mow your large lawn. Driving much like an automatic car, you have smooth and infinitely variable control over momentum. In addition, the machine starts with an easy to use push button, ensuring it is reliable and quick to get going, A large fuel tank of 11.4 litres means you can work for longer without stopping to refill, and the clever Cub Connect Bluetooth app allows you to effortlessly keep track of servicing and inspection intervals.
Comes with a 3 year conditional warranty.
Brand: CUB CADETPower Source: PetrolDelivery Info: ***RESTRICTIONS APPLY*** Tractors & ride-ons must be delivered by our own staff, so are subject to delivery restrictions within our range (we can deliver to other areas for a charge). For more info, click here
Why choose us?
Garden Machinery Direct is a family run business with over 40 years experience in selling and servicing garden equipment. We're one of the biggest garden machinery retailers in the UK. Based in the Midlands, we're well placed to deliver products across the UK - though we do deliver internationally. We are main agents for all the biggest garden machinery brands, and have fantastic working relationships with world leading manufacturers.
Our goal is to offer customers top of the range garden machinery at discount prices, delivered direct to your door. Our friendly and professional staff are available by telephone or email to give expert advice on the equipment most suited to your needs or to answer any queries you may have. We also operate an efficient spare parts service, utilising the latest computer link-ups direct to manufacturers stocks.
All of the garden machinery we sell carries a manufacturers guarantee, supported by a nationwide network of authorised service dealers.
At Garden Machinery Direct we offer our customers the best deals and even better service.
Please feel free to contact us if you have any questions.
Be the first to Write a Review for this item!
View the Cub Cadet brochure for more information.
TORO X5450 Zero Turn Mower£6,349.00 £5,799.00
This mower has a 137 cm cutting deck, anti scalp wheels and a powerful Toro 708 cc V Twin engine, delivering superb performances.
TORO MX427ST Zero Turn Ride-On Mower£4,499.00 £4,199.00
The MX427ST zero turn mower, features the incredible MyRIDE and a 708 cc twin engine.
TORO MX5075T Zero Turn Ride-On Mower£4,699.00 £4,399.00
The MX5075T mower features a 127 cm deck, the MyRIDE Suspension System and Smart Speed Technology, delivering superb results.


text:
Girl in a Dress, Jacket, Boots and Hat Kristi Tullus, http://sidrun.spire.ee Size 28 cm (11") tall, with DK weight cotton yarn and 2,25 mm and 3,50 mm crochet hooks. Difficulty 3. Intermediate – includes more complicated crochet stitches and techniques, basic lace pattern, color changes and small details. Skills required Crocheting in spiral, crocheting in rounds, chain, slip, single, half double and double crochet stitch, increasing and decreasing. Contact Info Pattern includes unlimited support from me over email or Skype. Crochet photo and video tutorials and helpful tips are available on my website. [email protected] http://sidrun.spire.ee a0kristi Copyright © 2014 TÜ Spire. All right reserved. Contents of this document MAY NOT be copied, reproduced, altered, published or distributed in any way. You MAY sell finished products made with this pattern, provided you credit me (KristiTullus, http://sidrun.spire.ee) as the designer. Tip! You can use the same pattern to make larger or smaller toys by using finer or bulkier yarn. Pick a crochet hook at least a size smaller than suggested on the yarn label and crochet tightly enough to achieve a tight gauge that will not allow the stuffing to show through the fabric. You may also need to adjust the size of the safety eyes. Materials & Tools • Yarn. I used DK weight cotton yarn, 95 m = 50 g (107 yds = 50 g) / 10 ply / 9 wpi. You will need about 55 g of beige, 40 g of white, 20 g of gray, 20 g of pink, 8 g of black and 15 g of DK weight alpaca yarn. • 2,25 - 2,75 mm and 3,50 - 4,00 mm crochet hooks (US size 1/B – 2/C and 4/E – 6/G) or according to the yarn. • Polyester fiberfill, wool, wadding etc. for stuffing. • 12 mm (1/2") safety eyes or buttons, beads, felt etc. • Cotton embroidery floss in dark brown and pink. • Satin ribbon and matching thread. • Buttons. • Yarn needle, sewing needle, scissors, stitch marker. Abbreviations • • • • • • • • • • • • • • • • • • • • st(s) = stitch(es). mr, sc n = crochet n (number) single crochet stitches in to the adjustable loop (see page 9). ch = chain stitch. sl st = slip stitch (single crochet stitch in UK and Australia). sc = single crochet stitch (double crochet stitch in UK and Australia). bpsc = back post single crochet stitch (see page ). hdc = half double crochet stitch (half triple or treble crochet stitch in UK and Australia). dc = double crochet stitch (triple or treble crochet stitch in UK and Australia). fpdc = front post double crochet stitch (see page ). sh = shell – crochet dc 2, ch, dc 2 in the same stitch. sc (or ch, hdc etc.) n = make n single crochet stitches (or ch, hdc etc.), one in each stitch. inc = increase – crochet two single crochet stitches in the same stitch. hdc-inc = half double crochet increase – crochet two half double crochet stitches in same stitch. dc-inc = double crochet increase – crochet two double crochet stitches in the same stitch. hdc-inc3 = crochet three half double crochet stitches in the same stitch. dec = decrease – crochet two stitches together using the invisible decrease method (see page 10). sc2tog = crochet two single crochet stitches together using the regular method. dc2tog = crochet two double crochet stitches together using the regular method. (sc 4, inc) x n = repeat the pattern between parentheses n times. (sc 4, inc) x 6 (36) = number of stitches in a round after finishing round. Girl Doll | Copyright © 2014 TÜ Spire | http://engsidrun.spire.ee 2
© Copyright 2020


text:
ELEVATED Rear Clear 2 oz.
Rear Clear will be your #1 for going #2. Designed for the "rear" this is everyone's #2 Life Saver. This is for every poop use, especially for those uncooperative, messy or stinky #2s. No more feeling like you used sandpaper to wipe your bottom, no more using the whole toilet paper roll and thinking "Is it clear yet?" Rear Clear is a spa for your bottom.
It keeps the rear clear, freshens the stinker, moisturizes, soothes, and even clears the (not so pleasant) #2 aromas.
Clears the Rear. Pampers the Pucker. Soothes the Sh*tter
- 2oz Amber Glass with Fine Mister Spray
- Clears the bottom and aroma after #2s
- Organic and Natural, Made in the USA
- Vegan & Cruelty Free – Leaping Bunny Certified
Directions: SHAKE Well & give a few sprays on toilet paper / wipe. Gently glide rear clear wipe across rear & enjoy a freshening, soothing pampering, & cleansing experience.
Ingredients: Aloe Barbadensis Leaf Juice, Witch hazel distillate (non-alcohol), Olea europaea (Olive) Fruit Oil Calendula officinalis flower Extract, Chamomilla Recutita (Matricaria) Flower Extract, Symphytum Officinale (Comfrey) Extract, Stellaria media (Chickweed) & Tocopherol; LAVENDER: Lavendula hybrida (Lavender grosso) Oil; AFTER DINNER MINT: Mentha piperita (Peppermint) Oil


text:
Groundbreaking Research: Israeli Scientists Can Create Personalized Tissue Implants
Israeli researchers at Tel Aviv University have invented the first fully personalized tissue implant, engineered from a patient's own materials and cells.
The new technology makes it possible to engineer any kind of tissue implant from one small fatty tissue biopsy.
"We were able to create a personalized hydrogel from the materials of the biopsy, to differentiate fatty tissue cells into different cell types and to engineer cardiac, spinal cord, cortical and other tissue implants to treat different diseases," says Prof. Tal Dvir of TAU's Department of Biotechnology, Department of Materials Science and Engineering, Center for Nanoscience and Nanotechnology and the Sagol Center for Regenerative Biotechnology, who led the research for the new research study.
"Since both the cells and the material used derive from the patient, the implant does not provoke an immune response, ensuring proper regeneration of the defected organ," Prof. Dvir says.View More Personalized Tissue Implants Now Available


text:
With the evolution of companies, markets and new financial trends, AROLA is committed to the development of integrated logistics covering offer and demand fluctuations, transport mode connection, tax deferment and the preparation of orders for distribution.
With several miles of m² in warehouses with different customs regimes, customs bonded warehouse, free trade warehouses and different Logistics Activities Zone locations, CIM, ports and airports, our objectives are to provide a flow of optimal material and services, to maintain adequate quality standards, reduce supply times and maintain competitive costs.
We analyse the main characteristics, regulations and documents on the goods and financial agents that intervene in the logistics chain in an individualised manner, offering the best solutions in each situation and organising the proper connection of inter-modal transport means with the infrastructures. The result is a high added value on AROLA's storage, supply and distribution services.
- Loading, unloading and stowage.
- Location and design conditions.
- Storage, hazardous materials and refrigerated cargo and goods subject to deferred tax regimes.
- Handling, palleting, shrink wrapping, labelling.
- Cargo fractioning and unit changes.
- Inventory maintenance, order processing.
- Protective packing and packaging.
- Goods treatment, picking, returns, reverse logistics.
- Storage insurance.


text:
India was able to get to a respectable score of 250-9 as Cheteshwar Pujara kept the visitors into the contest. Pujara scored a valiant century which was his 16th in red ball version. Pujara also completed his 5000 runs during the course of his innings. However, Pujara was given good support by Ravichandran Ashwin.
Australia dominated the first session of the day as they scalped four wickets by giving only 56 runs. There were some loose shots from the Indian batters as they all went for expensive drives. KL Rahul continued his dismal form going as he was looking to drive through the covers. Josh Hazlewood was the pick of the Australian bowlers as the vice-captain took two wickets in the first session.
Murali Vijay could only find a faint edge as Mitchell Starc was able to get the better off the Indian opener. Meanwhile, Pat Cummins took only three balls to take out the big fish, Virat Kohli. The Indian skipper who was looking aggressive in his batting approach, chased the fifth stump ball (one of the chinks in his armour when he is in young minutes of his innings).
Usman Khawaja flew like a bird to take a blinder of a catch at the gully position. Meanwhile, Ajinkya Rahane also chased off the wide ball to perish in a familiar fashion.
On the other hand, Rohit Sharma looked good for his knock of 37 runs. However, Sharma gifted his wicket as he tried to go for another big shot after getting riding on his luck on the previous hit.
Subsequently, Ravichandran Ashwin and Cheteshwar Pujara did the rebuilding work as the pair added 62 runs for the seventh wicket. Pujara scored his 16th century as the right-hander was the lone warrior in the Indian batting line-up.
Meanwhile, Pujara showed great resistance as he showed the stomach for the fight. The right-hander scored seven fours and two sixes in his pivotal innings of 123 to keep India in the game.
Pujara was solid in his defence and was able to punish the Aussie bowlers when they veered off the track. Furthermore, Pujara changed gears while batting with the tail. However, Pujara innings was ended with a brilliant bit of fielding from Pat Cummins.
Brief Scores: India 250-9, Cheteshwar Pujara: 123
Josh Hazlewood: 2-52


text:
Standing in front of over 100 people, Philadelphia Mayor and Wharton alumnus Michael Nutter proclaimed, "You really do count."
At a rally Wednesday night in the Lower Quad hosted by seven different student and faculty groups, Mayor Nutter urged all Penn students to complete their census forms, both for the good of Penn and the city as a whole.
"It's all about resources," Nutter explained. "About $400 billion from the federal government goes out to cities and states across the country based on census data," Nutter added.
The 2010 Census will determine how much of those resources are allocated to Philadelphia. Responding to a question about how the census will directly affect Penn, Nutter explained that important services on campus, from improving the streets to maintaining SEPTA and other forms of mass transit, receive funding based on census information.
Beyond the funding the census provides, the data will also help determine the apportionment of members in the House of Representatives from each state as well as the formation of state and local districts. Of the 435 House seats, states like Arizona, Florida, Georgia, Nevada, Texas, Utah and Washington are all expected to gain at least one additional seat.
Because this also changes the number of electoral votes each state has, the census will have ramifications for the 2012 presidential election as well.
"I hope this event will help inform students about the census," Wharton and College junior and Chairman of the Asian Pacific Student Coalition Rohan Grover said. "I believe Penn will exceed its previous numbers and will be able to count nearly everyone at Penn," Grover added.
Filling out the census form is quite simple. Mayor Nutter simplified the process down to a simple slogan, "10-10-10": 10 questions that take 10 minutes to complete with effects that will last for the next 10 years.
Students living on campus will receive the form in their mailbox and should drop it off at the collection boxes by their college house information center. Those living in Greek housing will receive and return forms to their chapter house manager.
College junior and Undergraduate Assembly President-elect Matt Amalfitano explained the role that the UA will play in informing students about the census. "An e-mail alone won't compel students," Amalfitano explained. "We're hoping to take it further, to connect with local student groups. A grassroots campaign is what will compel students to fill out their forms," Amalfitano added.
According to College Houses and Academic Services Associate Director for Communications Sue Smith, census forms are due nationwide by May 14.
Comments powered by Disqus
Please note All comments are eligible for publication in The Daily Pennsylvanian.


text:
Some travel destinations steal your heart in a way you just can't shake, and you have no choice but to get married there too! This was Lindsey and Andrew's feeling towards an Okanagan destination wedding. So they hopped a plane and flew across the country from Toronto for their dream day, along with their family and friends. And it was SO worth it! The beauty, the laughter, the tears, EVERY moment…
August in Kelowna can be super hot, but today was completely perfect. A few puffy clouds in the sky offered the occasional reprieve from the beating sun, while a cool breeze blew in across the shimmering waters of Okanagan Lake for this amazing, one of a kind wedding at Eldorado Resort. We are so excited to share the beautiful images from Jess and Andy Photographers, Planning and Styling with Jenny McAlpine Weddings, Makeup & Hair by Loyal Hair Therapy, Videography by PixelPro, Flowers by Lavender and Lace, DJ Krucial K "the Flyin' Hawaiian", and cake by Sugar Sweet Cake Co.
You are going to love this wedding story. And if you love beautiful sunset images you'll definitely want to read all the way to the end to see some incredible photos. Enjoy!
We sat down with Andrew and Lindsey to chat all about their wedding experience. Check it out below!


text:
Click on a picture to
The first two pictures clear up an omission in the last log. I forgot to take some pictures of the hose end with the coupling off. You can see the blue fitting has a profiled insert that goes into the hose and compresses it against the inside wall of the red fitting. The blue end also is threaded to screw into the red fitting.
The following two pictures show the routing and connection of the EGT and CHT senders.


text:
Restaurant General Manager
Vacancy expired!
Our message is simple: We exist to Feed People's Lives with Más. That means that sometimes you just gotta kick up some dirt, make some waves, blaze some trails, burn up the night, be the first one to head out and the last one to turn in, try what you've never tried before, make a play, and let it ride. If you never do this, you'll never know! At Taco Bell, we hope you'll discover your own way to Live Más!
As the General Manager, you are responsible for the operation of the entire restaurant and building a strong team that consistently provides customers great food and a friendly experience.
General Manager Responsibilities
- Oversee team members and Shift Managers and ensure they complete all assigned duties and serve safe, quality food in a friendly manner
- Finding, hiring, and developing excellent Team Members and Shift Managers
- Conducting New Hire orientation and developing the training plan for each new hire
- Scheduling and deploying the Team correctly, addressing performance issues and managing the restaurant budget and financial plans
- Ensure that the restaurant is a safe place for team members to work and customers to visit
- Make sure health and safety standards are met
Priority Sequence
- Safety
- Service
- Cleaning
- Stocking
What's in it for you?
- Top pay in the industry
- Trip to Mexico! Every year, we reward our top performers on our Best of the Best trip to Mexico. In 2020, we'll be taking 85 General Managers!
- Bonus program! Supplement your base salary with huge bonus capabilities!
- Education programs, including GED and Tuition Reimbursement offerings
- Scholarship opportunities
- Medical/Dental/Vision benefits offered for all positions – even part-time!
- Free food!
- Vacation Time (Paid Time Off), Sick, and Holiday Pay
- Vacation Donation Program
- Border Family Cares Program
- Border Smiles Program
- An incredible culture that encourages career growth and support
"You are applying for work with a franchisee of Taco Bell, not Taco Bell Corp. or any of its affiliates. If hired, the franchisee will be your only employer. Franchisees are independent business owners who set their own wage and benefit programs that can vary among franchisees."
Vacancy expired!


text:
Ohio Bureau of Criminal Investigation agents and supervisors raised repeated concerns about expired body armor for more than a year before a union grievance was filed this May, public records show.
Emails released by Republican Attorney General Mike DeWine's office shed new light on behind-the-scenes anxiety surrounding more than 50 bulletproof vests that had passed the five-year expiration date set by the National Institute of Justice.
"I WILL NOT ALLOW MY FOLKS TO GO THROUGH A SINGLE DOOR!!!," a BCI supervisor declared in one of the emails obtained by The Associated Press.
All vests are now on order, said DeWine spokesman Dan Tierney, following a report on the grievance by The Associated Press.
As he gathered statistics on the number of expired vests, one employee emailed he was "afraid to ask" how old one officer's vest was.
Another employee said the vest situation could "seriously limit personnel that are able to participate in search warrants and other law enforcement functions."
One law enforcement agent described a practice he'd started that he urged colleagues to follow: submitting a monthly photograph of his vest to management.
"This will create an e-mail paper trail that can be recovered by your spouse in case of any misfortune! (May the good Lord forbid this!)," he wrote.


text:
U heeft geen artikelen in uw winkelwagen
Imploding Kittens is the first Expansion of Exploding Kittens, the award-winning card game that made Kickstarter history as the most-backed project, ever.
This Expansion deck includes 20 new cards illustrated by The Oatmeal featuring 6 new types of actions and an Imploding Kitten which expands the game from 5 to 6 players.
Includes a human-sized "cone of shame," which is used as part of the game.
This is an expansion only. It requires a copy of Exploding Kittens.
0 sterren gebaseerd op 0 beoordelingenUw review toevoegen
is toegevoegd aan uw winkelwagen.
Niet op voorraad


text:
The CAA4SCBoy's/Girl's Basketball
Boy's/Girl's Basketball
This winter The CAA4SC will offer Boy's/Girl's Basketball at the High School and Middle School level. The CAA4SC State Final 4 and Championship Game will be February 16th-17th, 2018 and the location is Oak Ridge Military Academy, 2317 Oak Ridge Rd, Oak Ridge, NC 27310 . The CAA4SC-ALL-STAR Classic game is March 10th and the location is.
HS/MS Boys/Girls Basketball-
1st Rd (Monday Feb. 12th)
2nd Rd (Tuesday Feb. 13th)
3rd Rd (Wednesday Feb. 14th)
Thursday Feb. 15th will be used as a make up day
MS State Semi-Finals Friday Feb. 16th (Played at the higher seed)
HS D2 State Semi-Finals Friday Feb. 16th (Played at the higher seed)
High School D1 Final Four/Championship (HS Only): Friday Feb. 16th and Saturday Feb. 17 (@ Oak Ridge Military)
CAA4SC Amendments of Basketball Rules
*Game balls must be made by Under Armour and have official NFHS stamp.
*Visual clothing that is not considered apart of the school's uniform can only be one of the school colors. So if the undershirt is one of the uniform colors then it is consider legal. If the player has a black or white undershirt it too is considered legal.
*In the event that a player has a piercing or bracelet it can be covered with tape or a bandage.
*Players occupying marked free-throw lane line spaces may not enter the free-throw semicircle until the ball touches the ring or until the free throw ends. Play resumes once the ball is released from the shooter's hand.
*A running clock starts once a team is leading by 40 points at any point in the game. If the team that is behind cuts the lead to 30 points then the clock goes back to the normal operational clock. If it gets to a 40 point lead for the second time then it is a continuous running clock. The clock will only stop during time outs by either team or officials. The game can be terminated if both coaches agree on it.
* If a technical foul is given to a coach then that coach is allowed to remain standing. The coach does not have to sit. On the second technical foul on the coach he is then ejected.
Our Upcoming Curricular Events & Activities
Board Members
Get In Touch
Location: 2300 W Meadowview St, #206,
Greensboro, NC 27407
Telephone: 662-50-CAASC (662-502-2272)
Email: email@example.com
Email For Officials: firstname.lastname@example.com


text:
By Bachem AG
Contact Supplier
To get in touch with Bachem AG, simply fill out the form below.
Subscribe to Supplier
Bachem returns as sponsor to AsiaTIDES, Tokyo
Bubendorf, Switzerland: –Peptide technology specialist Bachem AG will be a leading presence at this year's AsiaTIDES oligonucleotide and peptide therapies symposium in Tokyo.
Once again, Bachem is a sponsor of the event, which will allow it to present its world-leading 'Pioneering Partner for Peptides' capabilities and product ranges , as well as its peptide synthesis technologies to Asian audiences.
High visibility
The Bachem stand (Booth 20) will be highly visible near the main entrance into the Exhibit Hall at Hilton Tokyo Bay Hotel and will showcase its extensive manufacturing capabilities of peptide-based APIs and research and production-focused custom synthesis services for research labs and pharma and biotech industries.
The stand will also feature latest developments, such as the ISO 13485 certificated production facilities and Bachem's custom synthesis service catering for milligram up to kilogram scales.
Bachem are delighted to be returning to AsiaTIDES, which is a unique event in Asia for promoting oligonucleotide and peptide research and development.
Linear vs. convergent synthesis
Dr. Samson (Vice President API SPPS) will deliver a presentation on 'Linear and Convergent Approaches to Peptide Synthesis – A Comparison from A Manufacturer's Point of View' during the afternoon of the final day of the conference. (1345hrs, February 28).
His talk will compare linear vs. convergent approaches for peptide synthesis, with pros and cons of each approach discussed from the point of view of production efficiencies.
About Bachem
The Bachem Group is the world's only full service provider of peptides and provides a full range of other services to the pharma and biotech industries.
Under its banner Pioneering Partner for Peptides, Bachem specializes in the process development and manufacture of peptides and complex organic molecules as active pharmaceutical ingredients (APIs).
A comprehensive catalog of innovative biochemicals for research and exclusive custom syntheses for research labs complete its service portfolio.
Headquartered in Switzerland with subsidiaries in Europe, the US and Asia, the group has a global reach and shows total commitment to quality, innovation and partnership to its customers worldwide.
Bachem prioritizes continuous investment in R&D on chemistries and technologies as crucial for future success. Its ever-increasing knowledge of complex proteins and peptides derives from ongoing research in proteomics, as well as progress in mass spectrometry, synthesis and ligation technologies, complemented by collaboration with external research institutions.
Bachem has six production sites in the U.S. and in Europe along with research level production and full cGMP manufacturing facilities on both continents. These provide capacity to produce APIs, key intermediates, small molecule generics, new chemical entities (NCEs) and finished dosage forms at preclinical, clinical and production scales.
About AsiaTIDES 2019
The AsiaTIDES Oligonucleotide & Peptide Therapeutics conference is the only event in Asia bringing together science, technologies and partners to accelerate oligonucleotide and peptide molecules to market. Th event provides a forum for leading companies to share strategies and network.
The 3 day 2019 meeting will be held on 26th – 28th February and is expected to attract more than 250+ oligonucleotide and peptide leaders across Asia, Europe and North America and will feature keynote addresses by Dr. Jesper Lau, (Vice President for Protein and Peptide Chemistry at Novo Nordisk A/S), Dr. Thazha Prakash (Director of Medicinal Chemistry at Ionis Pharmaceuticals), Dr. 'Mano' Manoharan (Senior Vice President of Drug Discovery at Alnylam Pharmaceuticals Inc.) and Dr. Chandra Vargeese (Head of Drug Discovery at WAVE Life Sciences).
The co-located exhibition will feature displays from more than 20+ global technology leaders, as well as peer-submitted posters that contain new and unpublished research from scientists working across all phases of oligonucleotide and peptide development.
The event is organized by KNECT 365 with further information at: https://lifesciences.knect365.com/asia-tides/


text: Iraq War Trending 1 Defence minister launches propaganda blitz ahead of Commons war crime debate Joe Glenton , 21st September 2020 Opinion 0 The US criminalisation of WikiLeaks can lead to only one outcome: journalists beware Tom Coburg , 12th July 2019 Analysis 1 UN Rapporteur questions Assange judge's role as more conflict of interest evidence emerges Tom Coburg , 26th June 2019 Trending 2 The BBC's Jon Sopel & ITV's Robert Peston ride to the defence of Alastair Campbell Joshua Funnell , 29th May 2019 Analysis UK military veteran 'eternally grateful' to Manning and Assange for 'profound impact on his life' News Chelsea Manning's lawyers file the 'strongest appeal' possible to secure her release on bail Opinion The Guardian's latest smear headline compares Labour's Brexit approach to the Iraq war Trending 3 Watching people give frank opinions on Tony Blair will restore your faith in humanity James Wright , 20th March 2019 Analysis 11 The WikiLeaks documents that should be written on New Labour's gravestone John McEvoy , 7th March 2019 Trending 1 Moving words show that Jeremy Hardy never stopped speaking truth to power Fréa Lockley , 2nd February 2019 Analysis 0 MI6 knew that a key source justifying the invasion of Iraq was tortured, but used his 'intelligence' anyway John McEvoy , 6th November 2018 Analysis 0 Here's the religion sustaining global terrorism that no-one's really talking about John McEvoy , 19th August 2018 Trending 0 A Blairite MP is facing the mother of all backlashes after one terrible tweet Nye Jones , 29th June 2018 Global 0 High Court rules British troops are guilty of cruelty, despite alleged government attempts at 'cover-up' Tom Coburg , 15th December 2017 Global 0 One of the world's leading universities has caved into pressure from spooks. That should terrify us all. [TWEETS] Tom Coburg , 20th September 2017 Global 0 Tony Blair thought he'd got away with invading Iraq, but he could now be in for a nasty surprise Sophia Akram , 6th July 2017 Global 0 A disturbing BBC video has resurfaced and it's a blow to Corbyn's critics [VIDEO] Tracy Keeling , 26th May 2017 Back to Top 1 2 3 4 Get the news that really matters Sign me up Start your day with The Canary News Digest Fresh and fearless; get excellent independent journalism from The Canary, delivered straight to your inbox every morning. Email Address First name Last name Mobile number (optional) Website ×


text:
As of late, an increasing number of self-publishers have developed a preference for CreateSpace over all the other options available on the virtual world. This online publishing system allows authors to publish their work with ease and within a short
Avoiding Inventory Worries Through CreateSpace Publishing
Publishing can be described as a difficult feat for authors who have not yet proven their writing prowess. The only way to get the attention of publishers in the past could be just out of sheer luck or by having
[Updated ]Reasons Why Authors Choose CreateSpace for Self-Publishing
The publishing world is aware of the fact that CreateSpace has already established a reputation of being a huge favorite among self-publishing authors. And there are many reasons behind this popularity. Aside from being a part of the Amazon network,
[Updated] CreateSpace Book Distribution Channel You Can Rely On
CreateSpace is one distribution channel of a kind. It has many advantages that make it standout among other distribution channels. For many years, CreateSpace has been a reliable and highly effective Amazon tool. It doesn't offer you publishing platforms only
Making the Most of CreateSpace: [Tips] for Indie Writers to Maximize their Experience
Independent book publishing can be a huge challenge, and can sometimes also be a financial nightmare for self published authors. Luckily, CreateSpace has made it easy for freelancers and self publishers to compete with the "big gun" publishers. And in
CreateSpace and Kindle Direct Publishing: Great Distribution Channels Writers Should Explore!
Wow…It's all done! At long last you've finished the final edits for your next book. Good for you! Now what? You are leaning towards self publishing, and are looking for a distribution channel that will help you publish and distribute
CreateSpace Trim Size and Bleed Specifications
Proper book formatting is one of the key factors that not only enhance the chances of your paper back being accepted by CreateSpace but also give it a professional look in line with mainstream publishing standards. However, certain minute details