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Mineral Content Of Mangoes Biology Essay
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The uniform, healthy, full-bearing mango trees (25 years old) growing under similar conditions from two commercial orchards, one in district Multan (30.15°N; 71.36°E) and other in district Lodhran (29.32°N, 71.38°E), Punjab province were selected for the experiments. Uniform sized, well-developed and healthy fruit were harvested at mature green stage from each tree. The fruit were treated with fungicide (Sportak), completely air dried (30 ± 2°C; 75-80% RH),packed in the corrugated fiber board boxes, and were shifted to Postharvest lab, Institute of Horticultural Sciences, University of Agriculture, Faisalabad (Punjab) by reefer van at 18°C. The study was comprised of two experiments.
Experiment 1: Comparative fruit quality of Mango cv. Samar Bahisht Chaunsa from two commercial orchards at ambient conditions (30±2°C; 50-60% RH) in relation to nutritional management.
The experiment was laid out according to the Completely Randomized Design (CRD), replicated thrice. Nine fruit were taken as replication unit. The fruit from two commercial orchards were kept under ambient conditions (30±2°C; 50-60% RH) for 6 days until fruits were ripened. The data were recorded regarding leaf mineral contents (at flowering, fruit set and harvest), soil mineral contents (at flowering, fruit set and harvest), fruit peel and pulp mineral contents (at harvest and ripening at each removal), physical characteristics of fruits (daily at shelf), organoleptic characteristics of fruits (on ripening) and biochemical characteristics of fruits (on ripening).
Experiment 2: Comparative fruit quality of Mango cv. Samar Bahisht Chaunsa from two commercial orchards in relation to nutritional management following cold storage (11°C; 80-85% RH).
The experiment was laid out according to the Completely Randomized Design (CRD) with factorial arrangements, replicated thrice (9 fruit per replication). Fruit were stored at (11±1°C; 80-85% RH) for 4 and 6 weeks. Following cold storage, fruit were ripened at ambient temperature (30±2°C; 50-60% RH). The data were recorded regarding leaf mineral contents (at flowering, fruit set and harvest), soil mineral contents (at flowering, fruit set and harvest), fruit peel and pulp mineral contents (at harvest and ripening at each removal), physical characteristics of fruits (every 4th day during storage and daily at shelf), organoleptic characteristics of fruits (on ripening) and biochemical characteristics of fruits (on ripening).
The experimental parameters were determined by using three types of samples:
Fruit samples
Leaf samples
Soil samples
Leaf Sampling
Leaf sampling was done at thee stages (at flowering, fruit set and harvest) to determine the status of different nutrients (Ca, Mg, N, P, K). The leaf samples comprised of 15-20 mature and healthy leaves were collected from the experimental trees at flowering, fruit setting and harvesting stage.
Soil sampling
Soil samples were taken from the soil of the selected trees between the trunk and the outer edge of the tree canopy. One sample per tree was taken from the surface to a depth of 15-20 cm with a soil auger. Soil sampling was done at flowering, fruit setting and harvesting stage.
Mineral Analysis
The mineral contents were determined in leaves of experimental trees and in the peel and pulp of the fruits to find out their relationship with fruit quality in mango cv. Samar Bahisht Chaunsa. For the mineral analysis of leaves, the leaf samples comprised of 15-20 mature and healthy leaves were collected from the experimental trees. First leaves were washed with tape water then water having 5% detergent in it and finally washed them with tape water again and rinsed with distilled water. Then the samples were air-dried. The dried leaves were ground to powder form. For peel and pulp mineral analysis, fruit were washed with detergent, rinsed with distilled water for 3-4 times and air dried at room temperature. Then peel and pulp samples were taken after peeling the fruit. These peel and pulp sample were already dried at 65°C, subjected to air drying under ambient conditions (25±1°C, 75-80% RH) for the period that no moisture could be found in the samples. Then these samples were subjected to oven drying at 65°C for 24-48 hours, grinded and the powder (about 100 g) was saved in plastic bottles for the determination of N, P K, Ca and Mg.
Digestion of the samples for determination of Ca, Mg, P and K
One gram of oven dried leaf material was transferred to a 100 ml beaker and 10 ml of concentrate HNO3 was added to it. It was allowed to stand till initial reaction was completed. It was covered with watch glass and low heat was provided until the solid material disappeared. After cooling, to each sample 5 ml of HClO4 was added and then again the sample was heated gently at first and then vigorously until a clear colorless solution resulted. When the volume reduced to 1 ml, it was cooled and transferred through filter paper to a 50 ml volumetric flask and the volume was made up to mark. This filtrate was stored in plastic bottles for further analysis to estimate Ca, Mg, P and K (Chapman and Parker, 1961).
A) Calcium
The Ca contents in leaves, peel and pulp were determined by using flame photometer (Flame photometer 410, Sherwood, Nottingham, England) as outlined by Sobkowska and Basinska (1975). The standard curve (Fig. 3.1) was obtained by using standard solutions of different concentrations. For the determination of Ca, the already prepared filtrate was fed into flame photometer at optimum sensitivity level and reading was recorded. The quantity of the element was found in ppm by comparing the emission (at 624 nm wavelength) of flame photometer with that of standard curve which was then converted to percentage by using the formula:
B) Magnesium
Mg was determined by atomic absorption spectrometry (Analyst-100, Parkin Elmer, Waltham, U.S.A.) at 318.4 nm wave length (di-nitrogen oxide-acetylene flame) as described by Vargas et al. (1994). The filtrate was fed to the apparatus and magnesium contents were recorded in mg/litre (ppm).
C) Phosphorous
The P was determined according to the method described by Chapman and Parker (1961). The standard solutions ranging from 0.5 to 5.0 ppm were made at a continuous difference of 0.5 ppm. For making standard solution, colour was developed by adding each of 5% 1:6 H2SO4, 5% ammonium molybdate and 0.25% ammonium vanadate. The standard curve (Fig. 3.2) was obtained by using potassium hydrogen phosphate instead of samples. Then the samples were fed to spectrophotometer (Evolution 300, Thermo Electron Corporation, Waltham, USA) at a wavelength of 420 nm and transmittance was noted which was compared with that of standard curve to find out the quantity of the element in ppm.
The percentage of phosphorus in the samples was calculated by using following formula:
D) Potassium
Potassium was also determined according to the method described earlier by Chapman and Parker (1961). Potassium concentration was determined by the flame photometer taking 5 ml of wet digestion material. Standard curve (Fig 3.3) was obtained by using potassium chloride.
The quantity of the element was found in ppm by comparing the emission of flame photometer with that of standard curve which was then converted to percentage by using the formula as under:
E) Nitrogen
For the determination of N, the procedure described by Chapman and Parker (1961) was used which included digesting the plant material (1 g) with 30 ml concentrated H2SO4 and 5 g digestion mixture (FeSO4: K2SO4: CuSO4 = 1:10:0.5). On cooling, the contents were then transferred to 250 ml volumetric flask and volume was made up to the mark. Then 5 ml of aliquot from this prepared material was distilled in micro-kjeldhal apparatus using 40% sodium hydroxide, 4% boric acid and mixed indicator of methyl red and bromo creso green (BCG). This distillate was titrated against N/10 H2SO4 till the original colour of methyl red was restored. From the quantity of acid used in titration, the percentage of N was calculated by using the following formula:
A = Quantity of acid used
B = Blank reading
0.0014 = Constant (which is equal to grams of nitrogen present in 1
ml of N/10 sulfuric acid)
Blank reading was taken for estimating the actual percentage of N in sample. All the procedure of digestion, distillation and titration was same for blank but it was done without leaf sample.
Physical Analysis
Following parameters were included in Physical analysis.
Respiration rate
One fruit from each replication was randomly selected and placed into a sealed plastic jars for 1 h. Respiration rate was determined by measuring CO2 production using a CO2 analyzer (Vaisala MI 70, Vaisala Inc., Helsinki, Finland) and expressed as mg CO2 kg‾¹ h‾¹.
Skin Colour
Skin colour development was scored manually according to the following scale used by Malik and Singh (2005), where 1 = 100% Green, 0% Yellow; 2 = 75% Green, 25% Yellow; 3 = 50% Green, 50% Yellow; 4 = 25% Green, 75% Yellow; 5 = 0% Green, 100% Yellow.
Textural softness
Textural softness was also scored manually using the scale used by Malik and Singh (2005) where 1 = Hard, 2 = Sprung, 3 = Slightly soft, 4 = Eating soft, 5 = Over ripe
Fruit weight Loss
Fruit weight loss was calculated on the basis of initial weight (before storage) and final weight (at the end of storage period).
Skin shriveling:
Skin shriveling of fruit were scored manually using the following scale described by Malik and Singh (2005), Where 1 = Nill, 2 = <10%, 3 = 10-25%, 4 = 25-50%, 5 = 50%
Injuries were assessed manually by scale used by Akhtar and Alam (2002) where 1= Nill, 2 = <5%, 3 = 5-10%, 4 = 10-25%, 5 = >25%.
Extent of internal breakdown
Extent of internal breakdown was assessed by scale already described by Raymond et al. (1998). The symptoms were visually rated as early, intermediate, or advanced. For Stem end cavity (SEC) rating of the symptoms was based on the presence and/or the size of the cavity at the proximal end of the fruit. Early symptoms of SEC were those in which no visible cavity was formed at the peduncular extension of the fruit. Symptoms of SEC were considered as intermediate when a 0.1-0.5 cm diameter cavity was visible at the proximal end of the fruit, accompanied by a necrotic area around that cavity. Symptoms were ranked as advanced when the cavity was larger than 0.5 cm diameter and was accompanied by deterioration of the fruit mesocarp around the stone.
For jelly seed and soft nose, early symptoms were characterized by a pronounced yellow colouration of the mesocarp around the stone (jelly seed) or at the distal end or at the sinus of the fruit (soft nose), indicating that the senescence process had been initiated. Intermediate symptoms were those in which the disordered mesocarp had an orange colour, whereas the surrounding tissue (exterior of the mesocarp) was still white or pale yellow, indicating that the exterior of the mesocarp was not ripe. Symptoms of jelly seed and soft nose were considered as advanced if the mesocarp showed advanced deterioration and/or discoloration.
Biochemical analysis
Biochemical analysis of fruit pulp was done to study the different components of fruit quality i.e. solubel solids content (SSC), titratable acidity (TA), ascorbic acid and sugars (total sugars, reducing and non reducing sugars). For the determination of biochemical components, all the fruits of each replication were peeled off with a stainless steel knife. The juice was extracted from each sample and homogenized to study the biochemical parameters.
A)Solubel solids content (SSC)
Digital Refractometer (RX 5000, Atago, Japan) was used for the determination of SSC. A drop of juice was placed on the prism of refractometer, the lid was closed and SSC (°Brix) was noted directly from the digital scale of refractometer at room temperature.
C) Titratable Acidity (TA)
For the determination of TA, method given by Hortwitz (1960) was used. Ten ml fruit juice was taken from each sample in a beaker, diluted (1:4) with distilled water and titrated against N/10 NaOH solution by adding 2-3 drops of phenolphthalein (C20H14O4) as an indicator. The results were expressed as % citric acid. Following formula was used for the determination of total TA.
SSC: TA ratio
It is calculated by given formula
B) Ascorbic acid
For the estimation of ascorbic acid in the pulp, the method described by Ruck (1969) was used. For this purpose extracted juice from each sample was filtered through Whatman® filter paper. Ten ml of filtered aliquot was taken in 100 ml round bottom flask, then volume was made up to the mark by adding 0.4% oxalic acid. Out of 100 ml aliquot, 5 ml was taken in a beaker and titrated against freshly prepared dye (2, 6-dichlorophenol indophenol) till light pink end point appeared which persisted for 10-15 seconds. For the preparation of dye, 42 mg baking soda (NaHCO3) and 52 mg 2, 6-dichlorophenol indophenol were taken in a 200 ml volumetric flask and volume was made up to the mark by adding distilled water. Ascorbic acid was calculated by using following formula:
D1 = ml dye used in titration of aliquot
D = ml of dye used in titration of 1ml standard ascorbic acid solution prepared
by adding 1ml of 0.1% ascorbic acid + 1.5 ml of 0.4% oxalic acid
A = ml of juice used
V = volume of aliquot made by addition of 0.4% oxalic acid
B = ml of aliquot used for titration
D) Sugars
Method described by Hortwitz (1960) was used to estimate the pulp sugars. Following solutions were prepared for determination of reducing and non reducing sugars:
i) Juice filtrate
ii) Invert sugar solution
iii) Fehling's solution
i) Preparation of juice filtrate
Ten ml of juice was taken in 250 ml flask in which 100 ml distilled water, 25 ml lead sub acetate solution (430 g of lead acetate/L) and 10 ml of 20% potassium oxalate solution were added. The volume was made up to the mark using distilled water. The solution was filtered and then the filtrate was used for the estimation of reducing and non reducing sugars.
ii) Preparation of standard invert sugar solution
As neutral or alkaline solutions of sugar should not be kept for longer time and should be prepared when required (Ronald and Sawyer, 1981); therefore standard sugar solution was freshly prepared. For the preparation of standard invert sugar solution, 23.75 g pure sucrose (analytical grade) was dissolved in about 120 ml water in a 250 ml volumetric flask, 9 ml concentrated HCl was added and the solution was kept for 8 days at room temperature for inversion of the sugar contents. On completion of inversion, volume was made up to the mark with distilled water (When inversion is complete, rotation in a 200 mm tube is 11.80°± 0.05 °S). Two hundred ml of the solution was transferred into a 2 L volumetric flask, 200 ml water was added and 71.4 ml of sodium hydroxide solution (40 g/L) containing 4 g benzoic acid was added along with continuous shaking. Then 1 L of distilled water was added, mixed, pH was adjusted at 3 and volume was made up to the mark. In this way, a stable 1% m/v stock solution of invert sugars was obtained which was diluted to make 0.25% standard solution and neutralized by using 1N NaOH.
iii) Preparation of fehling's solution
Fehling's solution deteriorates slowly so fresh fehling's solution was made sufficient to meet immediate requirements only. For the preparation of fehling's solution, equal quantities of solution A and B were transferred to a dry flask and mixed thoroughly. Fehling's solution A and B were prepared using following procedure.
Solution A: Copper sulphate pentahydrate (69.3 g) was dissolved in water and Volume was made up to 1 L.
Solution B: Sodium hydroxide (100 g) and 345 g sodium potassium tartrate (345 g; KNaC4O6.4H2O) were dissolved in water and volume was made up to 1 L.
Reducing sugars
The filtrate was taken in burette and titrated against 10 ml fehling's solution using 2-3 drops of methylene blue trihydrate (C16H18ClN3S. 3H2O) as an indicator with continuous boiling till brick red end point appeared. Reducing sugars were calculated by using following formula:
Reducing sugars (%) = 6.25 x (A/B)
A = ml of standard sugar solution used against 10 ml Fehling's solution
B = ml of sample aliquot used against 10 ml Fehling's solution
Total sugars
For estimation of total sugars, 25 ml of aliquot already prepared for reducing sugars was taken in a 100 ml volumetric flask in which 20 ml distilled water and 5 ml concentrated HCl was added and solution was kept for 24-48 hours for converting the non-reducing sugars into reducing sugars. Then it was neutralized with 50% concentrated NaOH solution and volume was made up to the mark (100 ml) with distilled water. The prepared solution was taken in burette and titrated against continuous boiling Fehling's solution (10 ml) to brick red end point using 2-3 drops of methylene blue trihydrate (C16H18ClN3S. 3H2O) as an indicator. Total sugars were calculated by using formula:
Total sugars (%) = 25 x (A/C)
A = ml of standard sugar solution used against 10 ml Fehling's solution
C = ml of sample aliquot used against 10 ml Fehling's solution
Non-reducing sugars
For the estimation of non-reducing sugars, following formula was used:
Non reducing sugars (%) = 0.95 x (% Total sugars - % Reducing sugars)
Total carotenoids:
Total carotenoids were estimated by the method given by Lalel et al. (2003). One gram of homogenized ripe fruit pulp was grounded with 0.05 g of magnesium carbonate in silica sand using glass mortar and pestle and centrifuged at 5000 rpm. Two extractions were made using 20 mL of acetone: n-hexane (75:60, v/v) mixture per sample. The extract was collected in separating funnel and washed with a 40 mL of 10% NaCl and 2 x 40 mL of distilled water to avoid acetone. The hexane extract was determined for its absorbance at 436 nm using spectrophotometer (Evolution 300, Thermo Electron Corporation, Waltham, USA) and was expressed as μg.g-1 of β-carotene equivalent from a standard curve of β-carotene.
Organoleptic evaluation
The fruits were evaluated at fully ripe stage for organoleptic acceptability on the basis of taste, flavour, pulp colour, texture and aroma using the 9 point hedonic scale described by Peryam and Pilgrim (1957). Nine judges were called in the panel for organoleptic evaluation of treatments.
Hedonic scale (Peryam and Pilgrim, 1957)
Product: ______________ Variety: _________________ Date: ______________
Name of Judge: _________________________ Signature: __________________
Instructions: (Please read the instructions carefully before filling the blanks)
This is an organoleptic evaluation form for different mango treatments.
Please follow the numerical system for scoring the samples.
Dislike extremely……………..1 Like slightly……………6
Dislike very much…………….2 Like moderately………7
Dislike moderately……………3 Like very much………..8
Dislike slightly…………………4 Like extremely…………9
Neither like nor dislike………5
Please do not disturb the sequence of the samples provided.
Please wash the tongue before testing next sample, with the water provided.
Sr. No.
Pulp Colour
Statistical analysis
The collected data was statistically analyzed using the computer software MSTAT- C (Russel and Eisensmith, 1983). Analysis of variance techniques was employed to test the overall significance of the data, while the Least Significant Difference (LSD) test (P ≤ 0.05) was used to compare the differences among treatment means (Steel et al., 1997).


text: Got a couple of resources for you here, both dealing with manhood, womanhood, marriage, and the gospel of Jesus Christ. The first is a 36-minute interview with the Family Policy Council of West Virginia. I did this with Jeremiah Dys of the FPC and thoroughly enjoyed myself. The second is a two-part interview with Carroll [Read More…]

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Greenhouse (Soilless) Media Testing
Samples are analyzed for pH, nitrate-nitrogen, ammonium-nitrogen, soluble salts, phosphorus, potassium, calcium, magnesium, sodium, boron, copper, iron, manganese, and zinc using the saturated media extract method with DTPA. The final report includes the analytical results along with an interpretation based on the crop specified.
Service Fees
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Fees effective 7/01/12 |
Soilless Media Kit | $40.00 |
Faxing reports (cost per page) | $1.00 |
Submitting Your Sample
Purchase a "Soilless Media kit" from your county Penn State Extension offices, collect your sample, and submit using the form below.


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News Roundup for December 8th, 2014
/Low Concept, High Fantasy
In the world of light novel Kuusen Madoushi Kouhosei no Kyoukan (Aerial Combat Wizard Candidate Instructor), mankind has retreated to floating cities against the threat of insect-like monsters. The army needs more mages to fight them, which is where ace-swordsman turned instructor Kanata Eiji comes in--except he's been assigned to train a squad of three girls with personality issues that are on a ten-battle loosing streak! See Eiji turn their quirks into perks when the anime adaptation hits in April.
Official homepage: Official homepage: http://ku-sen.jp/
What a Tease
Magical breast harem anime Highschool DxD will be back with a third season this April. The latest promo gives us a peak at Rossweisse, the purple-haired Valkyrie and Sairaorg Bael, Rias' cousin who loves a good fight. Head over to the official homepage to see the cast in action.
Official homepage: http://www.haremking.tv/news/#141261_tt
Damn It Feels Good to Be a Gangster
When you're surrounded by scum, getting your hands dirty is all part of a day's work. Drama CD turned anime TV series Gangsta follows Nick and Worick who play both sides of the law as they take care of dirty deeds for the cops and the mob in a city as corrupt as the pigs in charge. Animation studio Manglobe (Deadman Wonderland, Samurai Flamenco) brings these exploits to the small screen next July.
Official homepage: http://gangsta-project.com/
Ghosts 'n Giggles
High schooler Hibiki Amami sees dead people. But that doesn't stop her from having wacky fun with her friends in the yon-koma manga, Re-kan! While ghosts may not be able to find rest at least they can be comic relief when the anime adaptation haunts the airwaves next spring.
Official homepage: http://www.tbs.co.jp/anime/re-kan/
Keep Your Bearings
The new trailer for Yuri Kuma Arashi proves what I've suspected all along: that bears are invaders from outer space here to eat all the cute girls! It's a crazy setup for a plot, but director Kunihiko Ikuhara (Revolutionary Girl Utena, Mawaru Penguindrum) wears crazy as naturally as, uh, a space bear wears the skin of a bishoujo. Grab your bib because the yuri feast begin this January. Gao!
Official homepage: http://yurikuma.jp/
Super-size Your Prize
What's pink, soft and waiting for you to bury your face in it? These Super Sonico hand towels, of course! Win them and more merch in the latest Ichiban Kuji promotion for Super Sonico: The Animation. See the homepage below for the full spread.
Official homepage: http://1kuji.bpnavi.jp/item/900/
Kancolle for Gearheads
Kick your obsession for min/maxing into high gear with Shanago, a social game that gives you a garage full of anthropomorphic versions of flagship cars from Japan's top auto makers. Customize your ride, overhaul their chassis and become the fastest thing on four wheels. Just don't ruin that petite frame by putting a HEMI in it.
Official homepage: http://syanago.com/
Amplify the Flavor
Does feeding guitar feedback to miso make it taste better? Miso maker Marukome aims to find out with a new kind of sonic-enriched soybean. Look for this GMO (guitar modified organism) this winter.
Official homepage: http://misoshiru-s.com/


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Items where Department is "Lancaster University Management School" and Year is
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BBozkurt, Ödül Beyond national confines? : foreign employers and women managers in Japan. In: Work in Late Capitalism-- Feminist Reflections. . (In Press) MMason, Katy J. Effect of new organisational forms on market orientation: maximizing customer value services. In: Complexity and Management: A Collection of Essays. . Mason, Katy J. and Mouzas, S. Flexible business models. European Journal of Marketing. (In Press) |


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Lot 604: Lacoste René: (1904-1996) French Tennis Player & Businessman. Nicknamed "The Crocodile" Because Of His Tenacity On The Court. Worldwide Known As The Creator Of The Lacoste Tennis Shirts. Signed And Inscribed 6 X 8 Photograph Of Lacoste, In A Full Length Action Pose, Playing Tennis. Signed In Bold Blue Ink To A Light Area Of The Image. Vg
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Clarion Hotel Grand Östersund
Select your stay dates to check availability at Clarion Hotel Grand Östersund
Clarion Hotel Grand Östersund
About the Hotel
Property Location
A stay at Clarion Hotel Grand Östersund places you in the heart of Hornsberg, walking distance from Stadsmuseum and Badhusparken. This hotel is within close proximity of Ostersund Town Hall and Mid Sweden University.
Stay in one of 197 guestrooms featuring flat-screen televisions. Complimentary wireless Internet access is available to keep you connected. Bathrooms have bathtubs or showers and hair dryers. Conveniences include phones, as well as safes and desks.
Enjoy a range of recreational amenities, including an indoor pool, a sauna, and a fitness center. This hotel also features complimentary wireless Internet access, gift shops/newsstands, and tour/ticket assistance.
Satisfy your appetite at the hotel's restaurant, which serves breakfast, lunch, and dinner, or stay in and take advantage of 24-hour room service. Quench your thirst with your favorite drink at a bar/lounge.
Business, Other Amenities
Featured amenities include a 24-hour front desk, luggage storage, and an elevator (lift). Self parking (subject to charges) is available onsite.
Hotel Facilities
- Bar/lounge
- Smoke-free property
- Number of buildings/towers - 1
- Luggage storage
- Elevator/lift
- 24-hour front desk
- Restaurant
- Total number of rooms - 197
- Tours/ticket assistance
- Conference space
- Sauna
- Accessible bathroom
- Free WiFi
- Number of floors - 5
- Indoor pool
- Fitness facilities
- Free breakfast
- Coffee/tea in common areas
- Gift shops or newsstand
- Self parking (surcharge)
- In-room accessibility
Room Facilities
- Free WiFi
- Private bathroom
- Phone
- Bathtub or shower
- Desk
- Free cribs/infant beds
- Flat-panel TV
- In-room safe
- Iron/ironing board
- Hair dryer
- Rollaway/extra beds (surcharge)
- Room service (24 hours)
Hotel Policy
Know Before You Go
- Up to 2 children 12 years old and younger stay free when occupying the parent or guardian's room, using existing bedding.
- Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section).
The following fees and deposits are charged by the property at time of service, check-in, or check-out.
- Self parking fee: SEK 140.00 per day
- Pet fee: SEK 250 per pet, per night
- Rollaway beds are available for an additional fee
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
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A Dose of Deception
Miya, Pamela A.
Bibliographic Citation
American Journal of Nursing. 1996 May; 96(5): 67.
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Get an overview of this hotelHotel in Xining with restaurant and nightclub
Located in the heart of Xining, this hotel is within 1 mi (2 km) of QingHaiSheng KeXue JiShuGuan, Dongguan Great Mosque, and Nanliang Hutai Ancient Ruins Park. Xining Botanical Garden and QingHai DiKuang ZhanLanGuan are also within 1 mi (2 km).
Hotel Features
A restaurant, a nightclub, and a fitness center are available at this smoke-free hotel. Additionally, a bar/lounge, a coffee shop/café, and a sauna are onsite.
Room Amenities
All 141 rooms provide conveniences like refrigerators and coffee makers, plus 24-hour room service and TVs with satellite channels. Guests will also find minibars, hair dryers, and safes.
Information missing or incorrect? Tell us!Opens in a new windowTianniange Hotel
Hotel Amenities
Tianniange Hotel features a sauna and a fitness center. Dining options at the hotel include a restaurant and a coffee shop/café. A bar/lounge is on site where guests can unwind with a drink.
Business-related amenities consist of a business center and meeting rooms. This Xining hotel also offers a nightclub, a picnic area, and 24-hour room service.
Tianniange Hotel is a smoke-free property.
- 24-hour front desk
- Arcade/game room
- Total number of rooms - 178
- Number of floors - 10
- ATM/banking
- Babysitting or childcare
- Bar/lounge
- Business center
- Coffee shop or café
- Express check-in
- Express check-out
- Fitness facilities
- Gift shops or newsstand
- Hair salon
- Health club
- Tours/ticket assistance
- Meeting rooms
- Porter/bellhop
- Safe-deposit box at front desk
- Sauna
- Smoke-free property
- Supervised childcare/activities
Family Friendly Amenities
- Babysitting or childcare
- Arcade/game room
- Playground on site
Room Amenities
- Pay movies
- Air conditioning
- Phone
- Minibar
- Coffee/tea maker
- Daily housekeeping
- Turndown service
- Hair dryer
- Iron/ironing board
- In-room safe
- Television
- Room service
- Room service (24 hours)
Where to Eat
Tianniange Hotel has a restaurant on site.
24-hour room service is available.
Nearby Activities
Recreational amenities at the hotel include a sauna and a fitness center.
- Playground on site
Hotel Policies
Check-in time starts at 14:00:00
Check-out time is 12:00:00
Children and extra beds
- Children are welcome.
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.


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Report Corrections Here
Oklahoma County District Court
Oklahoma County Office Building
320 Robert S. Kerr Avenue, Room 409
Oklahoma City, OK 73102
320 Robert S. Kerr Avenue, Room 409
Oklahoma City, OK 73102
Phone: 405-713-1705
Online Court Resources
Resources for the Oklahoma County District Court as well as online resources applicable to courts generally in Oklahoma County, Oklahoma, and resources applicable to all courts in Oklahoma.
Search court case records
Oklahoma District Court Case Information
Search Oklahoma District Court case information by county, case type, date range, case number, party name and party type.
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Oklahoma Court Forms
View and download Oklahoma Court general court forms, child support, workers compensation and some juvenile forms.
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Oklahoma County Small Claims Information
View information on filing a small claims case in Oklahoma County District Court.
Oklahoma County Probate Information
View information about probate and guardianship matters in Oklahoma County District Court.
Oklahoma Small Claims Court Information
View answers to frequently asked questions about Oklahoma Small Claims Court.
Foreclosure Prevention Resources
View resources for preventing foreclosure in Oklahoma, including local housing counseling agencies, information about unlawful practices, and links to legal aid providers.
Oklahoma Expungement Information
View information related to the expungement of Oklahoma criminal and arrest records.
Oklahoma Court Mediator
View Information about Oklahoma Court mediation services and links to mediation centers throughout the state.
Oklahoma Court Rules
Oklahoma Court rules including District Court, Workers Compensation Court, Court of Tax Review, Court on the Judiciary, and rules related to the conduct of judges and attorneys.
Child Support Services
The Oklahoma Department of Human Services offers a variety of services related to child support, including legal information, an online application for services, and an online child support calculator.
Oklahoma Legal Research and Resources
Search Oklahoma laws, Constitution, cases, codes, and court rules.
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View information about Oklahoma Department of Human Services court-related services for children, seniors, and families. Select the "Services" menu item for links to specific services.
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View information about the Oklahoma County Public Defender office, which provides free legal representation to the indigent, juveniles, mentally ill, and adults and children in certain civil cases.
Attorney Complaint Forms and Information
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Complaints About Judges
The Council on Judicial Complaints investigates allegations of judicial misconduct and may recommend discipline by the Supreme Court, or removal or mandatory retirement of a judge by the Court on the Judiciary.
Oklahoma Domestic Violence Programs
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Oklahoma Free or Low-Cost Legal Assistance
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Toshimi Tanaka
Game Credits
Design | ||||
Last Resort (1992) | (Designers) | |||
Art/Graphics | ||||
Rhapsody: A Musical Adventure (1998) | (Battle Graphics: Monster (戦闘モンスターキャラクラー)) | |||
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Add to Added. 28 X-Frame Flat Steel Table Legs, 15 width table legs,. 28 X-Frame Flat Steel Table Legs, 15 width table legs, Height 26 to 32 SET(2). Shop outside the big box, with unique items for metal table legs from thousands of independent designers and vintage collectors on Etsy. Find great deals on eBay for Steel Table Legs in Tables. Shop with confidence. Pair (2) Metal H-Frame Table Legs – DIY Steel Table Legs 28 X 28. 125.00.
Industrial Metal Table Legs DIY Steel Table Base Steampunk Modern Salvage. The frame of this table is made of a 5mm rectangular metal tube, while the top is made of clear tempered glass. Table Leg World is your trusted source for custom metal table legs, stainless steel table legs, bases & much more! Customize your tables & desks today. For your own health and that of your employees our adjustable desk frames offer a modern solution to an old problem our bodies were not designed to sit for long periods. Well I will start with the shameless plug. My buddy and I design and hand make industrial table legs here in Portland, OR. Check out Steel Table Legs by Symm.
Our table legs and frames are available in heavy duty cast iron black or brushed stainless steel or chrome and other powder coated RAL colours. Table Frames – Electronic Height Adjustable View All. Find great deals on eBay for Metal Table Legs in Kitchen and Drinking Tables. Shop with confidence.
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what the living room of the cabin looked from upstairs.
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Invoice funding is similar to invoice factoring as both methods rely on accounts receivable to provide businesses with capital. However, when a company chooses to use an invoice factoring company, they retain their invoices, along with the responsibility to collect them. The invoice funding company, American Prudential Capital, will provide a certain percent of the value of the accounts receivable invoices which the business must repay within an agreed upon period of time.
Retaining ownership of the invoice can be advantageous to the business owner as the customer is unaware the business received invoice funding from an invoice factoring company. Invoice factoring is more like a cash advance against the value of the businesses accounts receivable invoices and must be paid back whether they are paid or not. This means that if the customer fails to pay the business, the invoice funding received from an invoice factoring company, like APC, must be paid with alternative capital.
Although there is some risk involved for the company, it isn't much more risk than obtaining a loan using traditional funding sources such as a bank or credit company. Invoice factoring is quite popular among establishments of all sizes but is especially popular among proprietors that haven't built a credit-history or sufficient collateral. Invoice factoring from a company like APC, is a great alternative funding source, providing them with a reliable solution to the sort of temporary cash flow issues organizations and startups often experience.
Invoice factoring companies, such as APC, readily provide alternative funding to businesses whose accounts receivable invoices bill with repayment dates from between 30 to 90 days. Invoice factoring is the perfect solution for those that are not well established and unable to obtain loans from traditional sources. By accessing the cash tied up in accounts receivable, they are able to keep their business flowing with enough cash-on-hand to make a difference and keep the doors open.
Invoice factoring companies, like APC, also help service businesses achieve the yearly growth needed to keep them in the game. Each time a company repays the invoice financing capital, the funding company then increases the amount of cash flow available for invoice factoring. This means they are able to build an expanding source or readily available cash for them to access. One of the most important aspects of owning a business is their ability to grow and without a ready source of fast cash, this may not occur. Obtaining alternative financing using invoice factoring allows them to purchase equipment, payroll, hire new employees, stock much-needed inventory, and to continue to grow.
As a small company grows, the invoice factoring company, APC, grows and increases the businesses access to invoice funding as the business shows their creditworthiness by paying back the funding fast and in full. Eventually, this creditworthiness will be recognized by traditional funding sources, allowing them to access funding through traditional loans. But APC will stand by every business for as long as needed, providing easy access to cash-flow through invoice factoring, a fantastic alternative finance funding solution.
One of the of the advantages of invoice factoring is that it allows the business to maintain complete control over their invoices, supplying as few or as many as they like to obtain financing. Invoice factoring companies, including APC, will never ask for a business to provide purchase orders from their accounts receivable that they aren't wishing to use. The company remains in control of all invoices, supplying the purchase orders they chose to have funded. Small business owners are able to decide which invoices they wish to have funded and will never be pressured to offer more or present invoices that add up to a certain cash amount.
Every company stays in complete control of their invoices. Not only does each business owner stay in control, the account receivables presented for invoice factoring to the invoice funding company can garner cash flow in as little as 24 hours. Proprietors are able to present the ones that will best provide the assistance needed to keep cash flow healthy, shelves stocked, payroll met, taxes and fees paid, utilities paid, equipment purchased and anything else the business needs to achieve growth. Invoice factoring companies like APC are only interested in how they can be of service to startups and small firms in Houston. Keeping them open and growing is their main concern and they are dedicated to providing alternative funding solutions to achieve just that.
Selecting Invoice Funding Services Versus Invoice Factoring Services
Invoice factoring allows company owners to retain full control over their financial systems, unlike invoice factoring which requires proprietors to sell their accounts receivables to the invoice factoring company. By keeping control of the business, customers will never know that the business has received alternative invoice financing from an invoice factoring company.
Surprisingly, invoice factoring companies report that invoice financing is not only great for small business but is the preferred financing method for a number of larger corporations as well.
Invoice financing provides funding that grows as the small business grows, allowing more funding to be accessed with each new invoice financing experience. Being able to increase working capital required and essentially build creditworthiness. Invoice factoring allows small firms to continue growing and operating without missing a beat.
Invoice factoring services may be the best option for financial staff that oversees rigorous credit control procedures that may prohibit borrowing from traditional funding sources.
Both invoice funding and invoice factoring services help proprietors receive the funds as they need them, often within 24 hours of approval. Both alternative funding methods allow proprietors to select the account receivables they wish to use and how much financing is desired. Each business simply selects the invoices and the cash amount needed. These then become collateral, staying in hand when opting for invoice factoring services and getting transferred to the invoice funding company when invoice factoring is selected.
Whether invoice funding or invoice factoring is selected as the alternative funding source, the creditworthiness is not factored into the financial arrangement. Invoice funding providers, such as APC, provide working capital without regards to credit, or lack thereof. However, invoice funding does consider the repayment history of past invoice funding transactions in order to upgrade the invoice financing amounts. As the business continues to repay promptly, the amount available for invoice financing increases.
Determining if invoice factoring service is the best option: Contact an APC finance advisor today to learn more.
To learn more about how invoice factoring assists small organizations and startups, just call the finance experts at APC today to speak with a trusted finance advisor. As one of the highest ranked invoice funding companies, APC has years of experience in finding alternative financial funding solutions for proprietors in Houston.
A cornerstone invoice factoring company, APC proudly serves small business pioneers, ensuring the backbone of America has the support and working capital required to continue to grow and expand. Call APC today and discover all the alternative funding solutions available for small business and startups of industries like a freight or a trucking company, even healthcare, and healthcare products providers.
- Or keep reading
- Acquisition Funding
- Growth Funding
- Invoice Factoring
- Purchase Order Financing
- Small Business Startup Funding
- Working Capital Financing


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Now that summer is in full swing, I find that I crave meals full of fresh and in-season foods.
My blogging friend Kate, of Modern Alternative Mama, recently released an ebook that covers some great tasting summer recipes.
I'm excited to have another cookbook in my kitchen to give me fresh, new ideas! I often tend to make the same meals over and over….and over.
From Kate:
Here, you'll find delicious marinated chicken for the grill, fresh salads, fruit dishes, party dips, pita chips, and even light desserts! All of the fresh flavors of summer, prepared to be light yet filling are in this book. If you want to cook seasonally…now it's easy!
In writing this, I was inspired by smoky grills, crisp salads, bright lemons and peaches, succulent tomatoes, and other key flavors of summer. These dishes are appropriate for parties and sharing — if you can bring yourself to share! (Just wait until you taste that bacon-wrapped chicken!)
Are you an allergy sufferer? Unsure if this book would work for your family's needs? This book comes with a set of icons to let you know which of the top 8 that each recipe is free of, making your recipe selection easier! Nearly half of the recipes are top 8-free, so this book will be appropriate for many with allergies, even multiple allergies!
I was sent this ebook a few weeks ago and will be adding a few of her recipes into my meal plan over the next couple of weeks. The salmon with dill and grilled parmesean potatoes are at the top of my list.
Kate has also decided to sponsor a giveaway her at NKU, so one of our community gets a chance to whip up some fantastic new food as well! (and it all looks to be very husband friendly too)
To Enter:
- Comment on this post
Additional entries:
(leave an additional comment for each entry)
- Check out the recipes offered in the book and let us know which you want to try
- subscribe to NKU
Entries will be accepted until Monday, August 6, 2012 at 6am.
Giveaway Fine Print
1) giveaway item will be as stated above. 2)Entrants must be over 18 and have a US mailing address. 3) Giveaway to run from 7/30/2012 – 8/06/2012 6:00am EST. 4) Entries will be considered when left as a comment, valid e-mail address required. 5) Winner will be chosen via random number by the WP plugin 'and the winner is….' and they have 48 hours to claim their prize after I send an email. 6) Duplicate entries will be deleted if found, contest will be extended is site issues come up. 7 ) giveaway sponsored by Modern Alternative Mama 8 ) No purchase necessary to win. 9) Prize not redeemable for cash. 10)Naturally Knocked Up, LLC is not liable for any injury or damage to persons and/or things as a result of the acceptance of the prize offered.
All images and content are protected under US copyright laws, please do not copy and paste.
Links in the post above may be affiliate or referral links - meaning that through a sale I may be given monetary benefit. I blog with integrity and only endorse companies and products I love.
I am not a doctor and don\'t pretend to be one. Use everything you read only to inspire you to do your own research and be an advocate for your own health. Please read my disclaimer in full.


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Lt213 47TH AVE PLEASANT PRAIRIE, WI 53158
Located minutes east of I-94 and just west of the heart of Pleasant Prairie, Village Green Heights is a beautiful 200-acre neighborhood with approximately 30 acres of open space including a neighborhood park. Only a few lots remain! Home and lot packages starting in the mid-300s.
Listing provided courtesy of: Korndoerfer Homes
General Features
- Tax Year 2015
- Total Taxes $1,446
- Directions I94W/US-41N to Exit 347, Wisconsin Hwy 165. Take Hwy 165 East approximately 5 miles to 47th Ave. Take 47th Ave north. Lot is on the west side of the street.
- County KENOSHA
Building Features
Room Features
Property Features
- Water Waste Municipal Sewer, Municipal Water, Sewer Laterals to Lot, Water Laterals to Lot
- Utilities Cable, Natural Gas, Telephone, Underground Electric
- Lot Description Level, Finished Lots, Curb/gutter
- Elementary School Prairie Lane
- Middle School Mahone
- High School Indian Trail
- School District Kenosha
Price & Status History
Days on Market
- This property has been listed on the market for 237 days


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Hassayampa Inn
Select your stay dates to check availability at Hassayampa Inn
Hassayampa Inn
About the Hotel
Property Location
With a stay at Hassayampa Inn in Prescott, you'll be minutes from Yavapai County Courthouse and Prescott Historic Downtown. This romantic hotel is within close proximity of Whiskey Row and Sharlot Hall Museum.
Make yourself at home in one of the 67 air-conditioned rooms featuring flat-screen televisions. Complimentary wireless Internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with separate bathtubs and showers feature complimentary toiletries and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.
Enjoy recreation amenities such as a 24-hour fitness center or take in the view from a garden. Additional amenities at this hotel include complimentary wireless Internet access and concierge services.
Satisfy your appetite at the hotel's restaurant, which serves breakfast, lunch, and dinner. Dining is also available at a coffee shop/café, and room service (during limited hours) is provided. Quench your thirst with your favorite drink at a bar/lounge.
Business, Other Amenities
Featured amenities include a business center, complimentary newspapers in the lobby, and dry cleaning/laundry services. Free self parking is available onsite.
Hotel Facilities
- Free WiFi
- Number of buildings/towers - 1
- 24-hour fitness facilities
- Meeting rooms 4
- In-room accessibility
- 24-hour front desk
- Business center
- Total number of rooms - 67
- Garden
- Free newspapers in lobby
- Safe-deposit box at front desk
- Coffee shop or café
- Restaurant
- Free self parking
- Dry cleaning/laundry service
- Luggage storage
- Bar/lounge
- Concierge services
- Accessible bathroom
- Number of floors - 4
Room Facilities
- Premium bedding
- Hair dryer
- Private bathroom
- Coffee/tea maker
- Connecting/adjoining rooms available
- Free local calls
- Free toiletries
- Free WiFi
- Separate bathtub and shower
- Iron/ironing board
- Free cribs/infant beds
- In-room climate control (air conditioning)
- Daily housekeeping
- Flat-panel TV
- Desk
- Cable TV service
- Room service (limited hours)
- Air conditioning
- Free bottled water
- Phone
Hotel Policy
Know Before You Go
- Children 17 years old and younger stay free when occupying the parent or guardian's room, using existing bedding.
- The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
- This property allows pets in specific rooms only. Guests can request one of these rooms by contacting the property directly, using the contact information on the booking confirmation.


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Lexus has been showcasing an edgy crossover concept for the past several months at major auto shows around the globe. The concept, called the LF-NX, previews a new compact crossover the Japanese automaker is planning to launch later this year, but it may have just been revealed. During a Society of... read more
The 2015 BMW M3 and M4 are here just a bit early--look for the full, official details later today--but we're not ones to look gift horses (or gift U.K. websites) in the... read more December 11, 2013 by Nelson Ireson
The latest C7 Corvette is one of the most capable sports cars on the planet, but in the tech department it's letdown slightly by its available six-speed auto. That may not be... read more December 9, 2013 by Viknesh Vijayenthiran
The 2015 Ford Mustang is all over the place--literally. First an early run of Autoweek outed the 2015 Ford Mustang in leaked images of its next issue. Then TIME added to the... read more December 4, 2013 by Nelson Ireson
Ferrari's latest special project car is getting closer to completion. This patent image leaked to Car News China appears to show a hardcore GTO version of the F12 Berlinetta... read more November 8, 2013 by Stephen Edelstein
The all-new 2015 Mercedes-Benz C-Class has been revealed in full thanks to these leaked photos. They show the car's front styling for the first time, revealing a look... read more October 29, 2013 by Viknesh Vijayenthiran
It isn't long before next year's most anticipated new car, the 2015 Ford Mustang, is revealed in all its glory. Now, full details of the new model have leaked, giving us full... read more October 28, 2013 by Antony Ingram
A photo depicting a completely undisguised version of the 2015 Hyundai Genesis sedan has hit the web, revealing the car in full ahead of its official online reveal later this... read more October 18, 2013 by Viknesh Vijayenthiran
This very well may be our first look at the completed design for Ferrari's replacement for its California convertible sports car. The images are alleged to be official... read more October 10, 2013 by Viknesh Vijayenthiran
Barely disguised prototypes for BMW's new 4-Series Convertible have been running around Europe for the past couple of months, but now we have the first official images... read more October 9, 2013 by Viknesh Vijayenthiran
Caterham has made quite the business out of selling updated and improved versions of the original Lotus Seven over the past several decades, but recently announced... read more September 19, 2013 by Nelson Ireson
The BMW 3-Series Coupe replacement, the new 2014 4-Series, has been six months in coming since its debut in concept form at the 2013 Detroit Auto Show. Today, the official... read more June 14, 2013 by Nelson Ireson
Mercedes-Benz this week started production of its sixth-generation S Class at its main plant in Sindelfingen, Germany, and in an official video showing the production line... read more June 14, 2013 by Viknesh Vijayenthiran
Photos of a slightly updated BMW M5 due on the market later this year have surfaced early, thanks to the inadvertent launch of the car's configurator on BMW's... read more May 14, 2013 by Viknesh Vijayenthiran
UPDATE: The 2014 Porsche Panamera has been revealed. Click here for all the details. We just brought you updated spy shots of the 2014 Porsche Panamera undergoing final... read more April 2, 2013 by Nelson Ireson
Though it isn't set for an official debut until tomorrow at the 2013 New York Auto Show, the facelifted 2014 Chevrolet Camaro was revealed earlier today on the Live!... read more March 26, 2013 by Viknesh Vijayenthiran


text: Chancellor Recommends Institution ConsolidationsToday, the University System of Georgia announced that the Board of Regents will act on a recommendation to consolidate Abraham Baldwin Agricultural College and Bainbridge State College at its meeting on Wednesday, January 11, 2017. While the proposed consolidation will present challenges, ABAC President David Bridges and Bainbridge State Interim President Stuart Rayfield pledge to work together to enhance educational opportunities for students. The announcement from the University System of Georgia can be found at: http://www.usg.edu/news/release/chancellor_recommends_institution_consolidations Presidents Bridges and Rayfield will reserve comment until the Board of Regents takes final action next Wednesday. |


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Malham Cove
This spectacular cliff was a backdrop for Harry Potter & the Deathly Hallows.
Built in 1705 as a yeoman's cottage, Beck Hall became a "wayfarers' hostel" in the 1930s. Over the years, this quaint, riverside cottage has grown into a little hotel that is now being lovingly restored by new owners Andy and Louise Macbeth. Beck Hall isn't posh or perfect, but its charming history, fairy-tale location and devoted staff make it a truly unique and friendly little hotel.
Think candlelit evenings by the babbling beck where you can enjoy delicious wholesome dishes cooked to order by head chef Louise.
Making the most of the best local ingredients available on Beck Hall's doorstep, the seasonal menus offer good honest British food with a Yorkshire twist.
Opening hours
Wednesday to Sunday From 6pm (Closed Monday & Tuesday)
Open from 12pm 7 days a week with a delicious new all day menu from Spring 2017!


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Duncan Sheik Covers Eighties on 20-City Sunset Sessions Tour
David Gordon • New York City • Oct 17, 2012
Tony and Grammy winner Duncan Sheik will headline a 20-city Sunset Sessions tour kicking off at the beginning of November in Las Vegas.
The musician will perform tunes from his new album Covers Eighties Remixed, which is set to be released on November 6 via his label Sneaky Records/MRI. The release features tracks by bands including Dépêche Mode, The Cure, and The Smiths.
City stops include Las Vegas's Cosmopolitan Hotel (November 9); New York's Gramercy Theatre (November 23), Nashville's 3rd and Lindsley (November 28); and Austin's Paramount Theatre (December 4), among others.
Sheik received Tonys and a Grammy Award for his musical Spring Awakening. He received a 1996 Grammy nomination for Best Male Vocal for his song "Barely Breathing." His theater credits also include Whisper House and the upcoming musicals American Psycho and The Nightingale.
- Duncan Sheik
- Gramercy Theatre
- Covers Eighties
- Covers Eighties Remixed
- Depeche Mode
- Spring Awakening
- Sunset Sessions
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Arsenic Trioxide in Treating Young Patients With Refractory Leukemia or Lymphoma
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die.
PURPOSE: This phase I trial is studying the side effects and best dose of arsenic trioxide in treating young patients with leukemia or lymphoma.
Condition | Intervention | Phase |
Leukemia Lymphoma |
Drug: arsenic trioxide |
Phase 1 |
Study Type: | Interventional |
Study Design: | Primary Purpose: Treatment |
Official Title: | Phase I Trial and Pharmacokinetic Study of Arsenic Trioxide in Pediatric Patients With Refractory Leukemia or Lymphoma |
Study Start Date: | March 2000 |
- Determine the toxic effects of arsenic trioxide in pediatric patients with refractory leukemia or lymphoma.
- Determine the maximum tolerated dose of this drug in this patient population.
- Determine the plasma pharmacokinetics of this drug in these patients.
OUTLINE: This is a dose-escalation, multicenter study. Patients are stratified according to disease (acute promyelocytic leukemia [APL] vs non-APL).
- Stratum I (APL patients): Patients receive standard-dose arsenic trioxide IV over 2 hours daily 5 days a week for 4 weeks. Treatment continues every 6 weeks for up to 3 courses in the absence of disease progression or unacceptable toxicity.
- Stratum II (Non-APL patients): Cohorts of 3-6 patients receive escalating doses of arsenic trioxide (according to the stratum 1 schedule above) until the maximum tolerated dose (MTD) is determined. The MTD is defined as the dose preceding that at which at least 2 of 3 or 2 of 6 patients experience dose-limiting toxicity. Once the MTD is determined, additional patients are accrued to receive treatment with arsenic trioxide at the recommended phase II dose.
Leukemia patients in both strata without progressive disease who have not achieved complete remission after the first 20 doses may continue to receive arsenic trioxide for 2 additional weeks.
Patients are followed every 3 months for 1 year.
PROJECTED ACCRUAL: A maximum of 18 patients will be accrued for stratum I of this study within 2-3 years. A total of 3-30 patients will be accrued for stratum II of this study within 1-2 years.
Ages Eligible for Study: | 2 Years to 21 Years (Child, Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
- Histologically confirmed leukemia or lymphoma refractory to standard curative treatment regimens
- Measurable or evaluable disease
- No meningeal leukemia or lymphoma
- No HIV-related lymphoma
- No lymphoproliferative diseases
2 to 21
- Acute promyelocytic leukemia (APL) patients (stratum I) must be age 2 to 12
Performance status:
Life expectancy:
- Not specified
- Not specified
- Bilirubin normal
- SGPT less than 2 times upper limit of normal
- No significant hepatic dysfunction that would preclude study therapy
- Creatinine normal (age adjusted) OR
- Creatinine clearance at least 60 mL/min
- Potassium, magnesium, and calcium at least lower limit of normal (oral or IV supplementation allowed)
- No significant renal dysfunction that would preclude study therapy
- Rate corrected QTc interval no greater than 0.48 on EKG
- No significant cardiac dysfunction that would preclude study therapy
- No cardiac disease, including dysrhythmias
- No significant pulmonary dysfunction that would preclude study therapy
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective contraception
- No persistent grade 3 or greater sensory or motor neuropathy
- No prior grand mal seizures (grade 3 or greater) within the past 2 years other than febrile seizures (except for patients with APL at discretion of investigator)
- No clinically significant unrelated systemic illness that would preclude study therapy (e.g., serious infection)
- HIV negative
Biologic therapy:
- At least 1 week since prior colony-stimulating factors (e.g., filgrastim [G-CSF], sargramostim [GM-CSF], and epoetin alfa)
- No concurrent immunotherapy
- No prior arsenic trioxide
- At least 2 weeks since prior chemotherapy (4 weeks for nitrosoureas) and recovered
- No concurrent intrathecal chemotherapy except for acute promyelocytic leukemia (APL) patients experiencing progressive meningeal leukemia and demonstrating benefit from arsenic trioxide for systemic disease
- No other concurrent anticancer chemotherapy
Endocrine therapy:
- No concurrent steroids (except corticosteroids for retinoic acid syndrome)
- At least 4 weeks since prior radiotherapy and recovered
- No concurrent radiotherapy
- Not specified
- At least 6 months since prior anticonvulsants
- At least 1 week since prior retinoid therapy
- No concurrent retinoids
- No other concurrent investigational agents
Please refer to this study by its ClinicalTrials.gov identifier: NCT00020111
Show 52 Study Locations
Study Chair: | Frank M. Balis, MD | National Cancer Institute (NCI) |
ClinicalTrials.gov Identifier: | NCT00020111 History of Changes |
Obsolete Identifiers: | NCT00004548 |
Other Study ID Numbers: |
Study First Received: | July 11, 2001 |
Last Updated: | April 28, 2015 |
Keywords provided by National Cancer Institute (NCI):
recurrent childhood acute myeloid leukemia childhood acute promyelocytic leukemia (M3) recurrent childhood acute lymphoblastic leukemia recurrent childhood large cell lymphoma recurrent childhood lymphoblastic lymphoma |
recurrent childhood small noncleaved cell lymphoma recurrent/refractory childhood Hodgkin lymphoma childhood chronic myelogenous leukemia atypical chronic myeloid leukemia, BCR-ABL1 negative |
Additional relevant MeSH terms:
Lymphoma Leukemia Neoplasms by Histologic Type Neoplasms Lymphoproliferative Disorders |
Lymphatic Diseases Immunoproliferative Disorders Immune System Diseases Arsenic trioxide Antineoplastic Agents |
ClinicalTrials.gov processed this record on March 24, 2017


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Item #A1990LA
Neon Blue and Aqua Glow Two Tone Long Wavy Wig
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Product Description
With two times the blue, this Neon Blue and Aqua Glow Two Tone Long Wavy Wig will help you become the most mesmerizing mermaid under the sea! This glamorous wig features brilliant aqua highlights and face framing layers. Wear it with your mermaid costume or use it to create a new and unique look!
Additional Information
Product Number: | A1990LA |
Material: | 100% Olefin |
Gender: | F |


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Sci fi/Fantasy image by
Laura Sullivan FosterMeet Trevor, another character in Mistletoe's Quest. You see, he's no ordinary Ogre (as though there's such thing as an ordinary Ogre...)! He used to be a nobleman, until a sorceress' spell transformed him. He's now searching for a way to become human again. He really relates to Mistletoe, because she, too, is now something other than the human she used to be. I thought I'd show him sketched, then inked, then 'finished' in Flash.
Published More than a year ago
Category Fantasy
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Categories > Celebrities > My Chemical Romance > Ashington
(#) annabel-lee 2011-04-16
Wilfred. LOL More soon?Author's response
Yeah I'll update tonight I'm writing as soon as I press respondAshington
(#) rainbow_apocalypse 2011-04-17
he he wilfred wtf lol it was not that bad :D updata as soon as you can pleae :)!!!Author's response
Yeah I will tonight I promise :) I completely forgot to finish the chapter last night
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Date: 1895 ca.
Description: Elevated view of Lake Geneva with the Lake Geneva steamboat.
Date: 1969-12-21
Description: Cupola-adorned top portion of the Van Bergen/Bowen house, 302 South Mills Street, built by Seth Bergin, a farmer and real estate investor, in 1846 in the I...
Date: 1894-05 ca.
Description: The Botkin house at the corner of Fairchild Street and Washington Avenue.
Date: 1940 ca.
Description: A marker at the site of the former village of Oshaukuta on highway 51, north of Portage. The marker states: "This tablet marks the site where the village o...
Date: 1963
Description: A boy taking part in a National Bicycle Week Celebration stands near a bicycle. Sterling Standiford, a State Trooper who was present to explain proper ope...
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Description: Log driving crew sitting down for lunch on the bank of a river (probably the Trap River or Rib River). There is a batteau at the water's edge, and one man...
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Date: 1960-02-23
Description: Once a year, members of the Shorewood Hills village board and members of the Blackhawk Country Club board of directors get together for a social evening to...
Date: 1915 ca.
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Date: 1937 ca.
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Date: 1959 ca.
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Date: 1969-12-28
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Date: 1905 ca.
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The Colt Government 1911 A1 - Ranking amongst the most successful gun designs in the world today, the Colt Government 1911 A1 is the predominant at the dynamic shooting competitions of the IPSC and the Bianchi Cup shooters. This model lives up to the high expectations of champions requiring a pistol for target competitions and fulfils the leisure role of snap fast shooting. This CO2 model will not disappoint.
Legal Notice to Customers - It is illegal to sell or hire an air gun of any type or style to a person under the age of 18. As a result, please do not be offended if we ask for proof of your identity to prove your age, as a law abiding and conscientous retailer we reserve the right to refuse any sale without reason or explanation.
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Alexander McQueen: Savage Beauty
Courtesy of The Metropolitan Museum of Art / Sølve Sundsbø / Art + Commerce
The first collection, 1992
In 1992, McQueen's graduate collection from London's Central Saint Martins College so impressed fashion editor and stylist Isabella Blow that she purchased all his pieces for £5,000. This satin coat from the collection, called Jack the Ripper Stalks His Victim, was inspired by the Victorian era, which fascinated McQueen for its "austerity, severity (and) melancholy."
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Lucha and Jamson exchange information in the aftermath of their accident.
Lucha remembers the day she left her childhood behind.
Jameson contemplates the multifaceted nature of his personality.
Lucha and Jameson connect at Lucha's performance of Orpheus and Eurydice.
Romance blooms on Lucha and Jameson's first date.
Lucha and Jameson share a passionate physical experience.
The metaphysical peak in Lucha and Jameson's love.
On their wedding day, Lucha gives Jameson a fateful gift.
Lucha receives a mysterious phone call from a voice she seems to recognize.
Before leaving Los Angeles, Orlando pays his last respects to his wife.
Reflect on the impact of a location's geography on a person's psyche.
In a state of darkness, Lucha is haunted by Jameson's red notebook.
Still submerged in darkness, Lucha dreams of Jameson's infidelity.
Lucha descends to the underworld in search of Jameson.
After years apart, Lucha and Orlando reunite in Los Angeles.
Lucha makes peace with Jameson's disappearance.
"We see young Orlando take a book off the shelf of Libros Schmibros book store in Boyle Heights. He reads the book in Spanish – Jose Ortega y Gasset's Meditations on Quixote – as he walks down 1st Street.
"Without looking up he finds his way in a car, where another version of him is playing on the cello. We then hear the voice of a third Orlando through the car speakers, from the stand-point of the future. He claims to barely recognize this younger version of himself, but he remembers the moment that he felt he was addressed from a voice that spanned generations: it was like a moment of calling.
"I think all of us who have dedicated our lives to the arts can remember similar moments, when a connection with a work of art strikes us like a thunderbolt, and a previously unknown destiny emerges as an inevitable path for our lives.
"Numbering the chapters was a back-and-forth process towards the creation of an arc that would add up if you could follow the characters chronologically.
"The older voice of Orlando speaks from a position that is closer to the Luchas of Chapter 29, Chapter 31, or Chapter 33 – and following Lucha's reminiscence of the supernatural connection she felt to Monteverdi's Orfeo in the previous chapter, this chapter shows Orlando experiencing the same thing with different results. But of course, and quite intentionally, no audience member could ever actually experience the piece in anything resembling a proper order. Depending on the direction the live audience travelled, the chapter that followed this one was either Chapter 4 or Chapter 17 – not Chapter 33. Like the Cortázar novel, I was hoping the audience would feel the sense of a center to the work, a place where all the various chapters connect, even if they cannot experience it. Beyond the post-modern aesthetic exploration of this sense of discontinuity, I think the existential implication of this idea was central to the concept of Hopscotch.
"I read Ortega y Gasset's essay immediately after reading Cervantes' original – I'm not sure I felt as thunderstruck as Orlando, but I've never forgotten the brilliance and clarity of his ideas, and I think many of them shaped some of the philosophical underpinnings of Hopscotch. The young Orlando reads a part I thought about a lot in the early stages of Hopscotch: 'When shall we open our minds to the conviction that the ultimate reality of the world is neither matter nor spirit, is no definite thing, but a perspective?' Or even more powerfully: 'I am myself plus my circumstance, and if I do not save it, I cannot save myself.'
"Gabriel Garcia read the text as if to himself – but to make sure he didn't have to sacrifice that illusion while on the street, we gave audiences headphones for their walk from the car to Libros Schmibros bookstore. The amazing result was not just the more intimate connection of his voice in our ears, but the sound of the streets were also amplified and alienated through the process. I loved that the ideas of the Ortega y Gasset, which ask us to consider how the circumstances of our lives shape who we are, was not only better heard through the headphones but brought to life."


text: The icons of the Civil Rights Movement of the 1960s are celebrated and well-known, but there were countless foot soldiers working for justice alongside Martin Luther King, Malcolm X, Rosa Parks and Medgar Evers. One of the Justice Department's foot soldiers was Gordon Martin. In the early 1960s, he was a young, idealistic lawyer who was sent down to Hattiesburg, Mississippi to interview blacks who had been denied the right to vote by a Forrest County clerk of court. Martin helped prepare the case against Theron Lynd and wanted to celebrate the brave witnesses who stood up for their democratic rights years before the Voting Rights Act of 1965. Martin's book about his experiences is titled Count Them One by One: Black Mississippians Fighting for the Right to Vote. The book also follows Martin as he finds and talks with the witnesses on how things have changed over the past 50 years.


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John Leslie Waters
Found 10 Records, 10 Photos and 1,846,430 Family Trees
Born in Amador City, California, USA on 1914 to Frederick Tyack Waters and Edith A Lessley. John Leslie married Doris Adeline Gebhardt and had a child. He passed away in Folsom, California, USA.
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Surname meaning for "Waters"
English: patronymic from an altered form of the personal name


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They've taken the Minecraft world by storm with their fun-packed gameplay and animation and now Little Kelly, Little Carly and MineVengers bring their brand of fun to GamerCon Dublin. All will be part of the YouTuber meet and greet that will take place at GamerCon Dublin on March 18th and 19th 2017.
'My 7 year old daughter loves these guys, so I've been familiar with them for some time, so I'm delighted that we can have some homegrown stars of YouTube be at the event to meet their fans in this way' (GamerCon founder – Ferdi Roberts).
Little Kelly, Little Carly and MineVengers will appear on both the 18th and 19th March at GamerCon Dublin at the Convention Centre Dublin.
enquiries: firstname.lastname@example.com


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Life hasn't been quite the same for computer engineer Island Chaptal since March, when an OCD-ridden professional killer burst into her life to clean her bedroom and take her on a global chase for a legendary diamond. Sadly, the (hit) man doesn't just break bones; he breaks hearts, too.
Since then, Island has found solace in Alex - the perfect boyfriend - and Ruby, a software project about to revolutionize online banking security...for the worse. When Island's boss is found dead after allegedly using Ruby to steal a vast fortune, it's up to her to clear his name and recover the money. Someone else wants answers, though, and this time, Island might be in over her head.
From New York to Zürich, it's going to take the return of a cleaning expert, a mini-octopus, and Island's wits to beat Ruby. All while deciding whether to trust a man who already jilted her, or one who may have his own deadly secrets...
©2016 Camilla Monk (P)2016 Yaypub
"Totally great series!"
Island and March on their second "mission" was as good as their first. The love March has for Island is beautiful and she loves him back. There is a 3rd book in this series that recently came out. I decided not to listen to it until the 4th one is coming out. Don't want to end the series so putting off the 3rd for a while will prolong it a bit. Don't hesitate - chose to be entertained by mystery, unrequited love, murder and a bit of James Bondism!
Say something about yourself!
"Love it twice!"
This is an enjoyable series. The fun continues. The best line for this book… Island is dressed up to get in a club. The bouncers are Germany. She says to them, I am very rich, barely dressed, and very low self-esteem, can I get in? Her Germany is not her strong language.
Island is always pulled into situations trying to illustrate the best in someone. This time her, new boyfriend, Alex and of course March are off to find Ruby. All the Island and March stuff you normally expect to find is here. I have already given you one of the best lines.
The comedy continues in the juvenile manner in which Alex and March fight for the attentions of Island and the gift of her virginity. Of course, no one can do it better than March. Island is still throwing herself in front of guns to keep someone from getting shot. She gets her attitude on and gives March and Alex a much-needed check with all the tongue wagging that a pissed off woman can give. March and his OCD issues still offer many of laughs. March has made an impressive gesture in his affections for Island. I just hope that it does not lower his body count.
Amy McFadden does it again! What a wonderful listening experience. March is back and Island is right back in the mix of her mother's old life! Even if you have already read this you need this audiobook! It really brings the story to life. I would give it more than 5 stars if I could.
"My go-to escape!"
I LOVE this series! These books have all the elements found in my favorite books all rolled into one: romance, humor, mystery, unpredictability, action, sexual tension. . . maybe I'd like a bit more sex, but I'm freaky that way! I've listened to this book no less than three times. I put it on when I need a chuckle or am tortured with some mindless task like cleaning. This author has a fan for life!
And the narrator? She flawlessly brings the characters to life. Some narrators lose me when switching around to voices of the opposite sex or accents. Amy really pulls you into the story. I sure hope she continues her recording career as I'll be following her also!
Great story, lyrical narrator, edgy suspense, intelligent writing, Laughing Out Loud (seriously)! Books and Audible don't get any better. I now have a new standard for 5 stars.
"eating live animals? really?"
I liked the first book in the series despite the absurdity of the grown woman who can't lose her virginity. Still, the story itself was really good and kept me hooked.
This time around its the same old story in terms of virginity. I could live with it until the main characters started eating live animals. The author is very talented so not sure why she sunk to the shock value. It appears to have nothing to do with the plot, so I'm quitting here.
Amy McFadden is incredible - so good!


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When it comes to the Pentagon, the GOP says, "What Deficit"?
The Pentagon has been a financial burden for the last 50 years. They are a necessary evil, but it's time to rein them in. Taxes should be raised for the super income 2% American population and it's also the Pentagon's turn.
Pam in Oregon
Correction to Post:
The Pentagon has been a financial burden for the last 50 years. They are a necessary evil, but it's time to rein them in. Taxes should be raised for the super income 2% American population and it's also the Pentagon's turn for a budget reduction.
Pam in Oregon
$400 billion is a drop in the bucket. How many $500 hammers is the Pentagon buying these days?
You cannot be serious about deficit reduction without cuts in Defense Spending. It is long overdue....
Pentagon better get used to belt tightening. It can no longer rely on the flag waving sunshine patriots in the GOP/Tea Party to support a large defense budget.
Buck McKeon's idea of "constitutional responsibility" to provide for defense, is keeping his California defense contractors in the big bucks.
I would welcome defense spending cuts . Progressives have been saying for decades that wars and defense would break the bank. If we look at the numbers real close well- it turns out to be true.
Lets fire more teachers. With the huge savings from those bloated teacher salaries, we could double our military. Get those space jockeys back into business at same time, blast that money off into space.
It is quite simple. Reduce the budget. Period. Let the Pentagon big-shots figure out the details.
Mr. Boehner is supposedly for cutting wasteful spending. The frigging ARMY says that they have more than enough M1A1 tanks [which happen to be built in Boehner's district]. But guess what, Mr. Boehner wants to OVERIDE the Pentagon, the people that know best and continue to have these tanks built. He has ZERO credibility – cut everybody elses spending but leave mine alone.
Beyond Boehner, the DOD's budget is like $720 BILLION this year and in just the past 10 years is has almost DOUBLED. Tell me what other SPENDING has DOUBLED over this period? If we had frozen spending at 2001 levels we'd have saved TRILLIONS!
So that we are clear, everyone should understand that extra spending was covered by borrowing money from China. It is part of the $14.3T National Debt that the Republicans are now trying to hang around Obama's neck.
I really don't want to hear anymore BS from the Republicans about "America's defense". You guys talk a good game but can't execute for $ _ _ + It was Obama that got Osama, not the paper tigers that talk tough. The gravy train for your Blackwater buddies is over. They've gotten rich enough from this GOP backed SPENDING.
Close foreign bases or make host countries pay the cost.
ABOUT DAMN TIME.. I'm all about keeping the country protected against external threats and such, but the DoD is probably one of the biggest reasons why we're in this debt crisis. The Military should be downsized. We do not need to maintain 737 military bases in foreign nations. This is a waste. We spend more on the military than every other country in the world put together? And for what? The war in IRAQ was illegal and had no point – there were no WMAD's, the country is still a mess and our oil is no cheaper. The war in in Afghanistan was to find OBL. We basically spent 10 years of our armed forces resources searching for ONE MAN – and we made Al Qaeda stronger in the process. Contractors are feasting off our taxpayer dollars. What are we so afraid of as a country? We spend so much to protect a country that we aren't even investing in! It totally frustrates me that our infrastructure and education systems are crumbling and we've lost the will and capacity to innovate. So I'm happy that at least the conversation is being had with regards to military spending because it seriously needs to be cut for our own survival as a nation.
Keep an eye on this one. Wall St. ended up driving America into the ground and then got rewarded for it. The military-industrial complex will be just as resistant, if not more. While many of the GOBPbaggers are neocon nutjobs, I welcome any decent Republican willing to acknowledge our military is grossly oversized. We don't need it, we can't afford it, and America has no business being the world's policeman or providing bodyguards for Big Oil.
cut! cut! cut! Our biggest threat today is some clod in jerkistan somewhere hacking into our power grid and throwing us back into the dark ages. Why do we need billions of dollars on new weapon systems when we have drones and cruise missiles to take him out?
The Pentagon could cut $400 Billion in a week, but who is going to willingly give up all that free money – certainly not those that have all the guns.
Leave th millitary alone and let them defed this country from all whom wish us harm. Their are too many enemies poised to strick us form any direction remeber that when you start your cuts.


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Pokemon Adventures Heart Gold Soul Silver : 1 Paperback
by Hidenori Kusaka
Part of the Pokemon series
All your favourite Pokemon game characters jump out of the screen into the pages of this action-packed manga!
Pokemon Trainers Gold and Silver are back! Crystal too! And so is Team Rocket...In this two-volume thriller, troublemaker Gold and feisty Silver must team up again to find their old enemy Lance and the Legendary Pokemon Arceus.
Meanwhile, Team Rocket is on the rampage digging up, stealing and collecting 16 mysterious plates for some nefarious purpose known only to them...What is the hidden power of the 16 plates, and what do they symbolize...?
- Format: Paperback
- Pages: 208 pages, Illustrations
- Publisher: Viz Media, Subs. of Shogakukan Inc
- Publication Date: 10/10/2013
- Category: Manga
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We've never been disappointed at Maggie's. The food is good (typical tavern fare), the beer is cold and the service (love the ladies that have been there for decades!) is warm. Popcorn a nice bonus. Always fun to munch on while you wait.
Went into Maggie's for drinks on date night. Popcorn was fabulous and drinks very cold and a great selection! The staff was very friendly. Nice atmosphere Would return here in a heart beat
Nothing fancy, but good, clean decor - great AMERICAN food, fair prices and great service. Lots of good places to eat in Cadillac, but for very casual dining, we usually stop here. Never had a bad meal and the popcorn is free. BONUS!!!
Great food, great beer! Little bit of everything to offer. Still has that "old school" feel. Staff is always pleasant!!
This place is a tradition when in the area for our family. We had a variety of meals and everything looked good. Our favorite is their wet burrito which is large enough to share. The service was excellent and friendly.We had burgers at our first visit and found them to be only average. The meat appeared to be from a... More
I grew up in Cadillac and have always had the best of service and food at Maggies. The popcorn is always delicious and the servers are impecible. One of the ladies there, Tami is the sweetest most loving lady. 10/5 would recommend.
A little of everything on the menu- Irish, Mexican, and American. It was a nice place with church pew seating and animal heads on the walls. The burger was typical bar food and the service was OK. Very average experience but decent food at a decent price.
The atmosphere is fun. Good food and pleasant service. Loved the popcorn and cookie that came before and after the food. Decent prices.
Great service, especially the older lady that works there often. however, the food was the worst. Dont get the roast beef sandwich or any burger. Frozen patties. The roast beef was like plastic and the gravy was like salt paste. I got so sick. :(
We have stopped here for over 13 years. Nice friendly, place, with great specials. Everything we have tired is very good.
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Flight United Kingdom Malaga
Looking for flights from United Kingdom to Malaga? Planning a holiday in Spain and want to find out where you could fly from in United Kingdom? If so, we've got the right deals for you. Eurowings flies to Malaga from just £79.99* and is looking forward to welcoming you on board for your journey to Spain soon. The best price for a flight from United Kingdom to Malaga by month is shown in the overview.
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I clean houses do pretty much anything you need done. I can give work references and reasonable rates.
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