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U.S. Attorney Preet Bharara applauded a judge's ruling in a major fraud case. Richard Drew/AP hide caption toggle caption Richard Drew/AP The Two-Way Judge Orders Bank Of America To Pay $1.3 Billion Fine July 30, 2014 A jury had found the bank liable for fraud related to mortgages sold by its Countrywide Financial unit last October. Bank of America may appeal.
Attorney General Eric Holder, seen here Monday, has supported changes in drug sentencing, but the Sentencing Commission went further than he preferred Pablo Martinez Monsivais/AP hide caption toggle caption Pablo Martinez Monsivais/AP The Two-Way Drug Sentencing Guidelines Reduced For Current Prisoners July 18, 2014 More than 46,000 inmates can petition for early release starting next year, unless Congress acts soon.
Nashville Tennessean Editor John Seigenthaler testifies at a Senate Commerce Subcommittee hearing in Washington in 1969. Seigenthaler died Friday at 86. Bob Daugherty/AP hide caption toggle caption Bob Daugherty/AP The Two-Way Newspaper Editor, Activist John Seigenthaler Dies At 86 July 11, 2014 He worked for The Tennessean and took leave to assist Robert F. Kennedy in the White House and during the senator's 1968 presidential campaign. He later helped shape USA Today.
New Jersey Democrat Robert Menendez, chairman of the Senate Foreign Relations Committee, has asked the Justice Department to investigate a smear campaign against him. Alex Wong/Getty Images hide caption toggle caption Alex Wong/Getty Images The Two-Way Senator Asks U.S. To Investigate Possible Cuban Plot Against Him July 8, 2014 Did fake accusations that Sen. Robert Menendez had visited underage prostitutes come from Cuba's intelligence agency? That's the question the senator wants the Justice Department to look into.
A photo provided by the U.S. Marshal's office shows terrorism suspect Adel Daoud, of Hillside, Ill. Daoud, a 20-year-old U.S citizen, has denied government allegations that he accepted a phony car bomb from undercover FBI agents in 2012, parked it by a Chicago bar and pressed a trigger. Uncredited/AP hide caption toggle caption Uncredited/AP The Two-Way Court Overturns Sharing Of FISA Surveillance With Defense Lawyers June 16, 2014 The 7th Circuit Court of Appeals says that the Justice Department can keep intelligence information secret in terrorism cases.
The Two-Way In A Standoff With Montana Officials, The Justice Department Blinks June 10, 2014 Two years ago, the Missoula county attorney defied the DOJ's efforts to force his office to change the way it handles sexual assault cases. Today, the county won a partial victory.
Department of Justice The Two-Way New DOJ Policy Urges Agents To Videotape Interrogations May 21, 2014 The policy shift, set to take effect July 11, is designed to align practices across the federal government, where some law enforcement agencies employ recordings and others don't.
Press materials are displayed on a table at the Justice Department in Washington on Monday before Attorney General Eric Holder was to speak at a news conference. Charles Dharapak/AP hide caption toggle caption Charles Dharapak/AP The Two-Way U.S. Files Criminal Charges Against Chinese Officials Over Cyberspying May 19, 2014 The Justice Department accuses five Chinese officials of stealing trade secrets by spying using military and intelligence facilities. These are the first charges of their kind to be made by the U.S.
The Two-Way Karl R. Thompson Tapped To Lead Key Justice Department Unit March 25, 2014 Thompson has been named acting head of the Office of Legal Counsel, which approves executive branch legal arguments on armed drones, surveillance and other national security issues.
Debo Adegbile, special counsel of the NAACP Legal Defense Fund, speaks with the media outside the Supreme Court in Feb. 2013 after presenting arguments in the Shelby County, Ala., v. Holder voting rights case. Evan Vucci/AP hide caption toggle caption Evan Vucci/AP It's All Politics Senate Democrats Defect On Obama Civil Rights Nominee March 5, 2014 The clash over attorney Debo Adegbile's Justice Dept. nomination pitted powerful law enforcement interests against the civil rights community. Senate Democrats Defect On Obama Civil Rights Nominee Listen · 4:28 4:28 Toggle more options Download Embed Embed <iframe src="https://www.npr.org/player/embed/286393192/286408085" width="100%" height="290" frameborder="0" scrolling="no" title="NPR embedded audio player"> Transcript
Senate Democrats Defect On Obama Civil Rights Nominee Listen · 4:28 4:28 Toggle more options Download Embed Embed <iframe src="https://www.npr.org/player/embed/286393192/286408085" width="100%" height="290" frameborder="0" scrolling="no" title="NPR embedded audio player"> Transcript
A bag of marijuana being prepared for sale sits next to a money jar at BotanaCare in Northglenn, Colorado, in this file photo taken on December 31, 2013. Rick Wilking/Reuters/Landov hide caption toggle caption Rick Wilking/Reuters/Landov The Two-Way Feds Clear Banks To Do Business With Budding Pot Industry February 14, 2014 The departments of Treasury and Justice signal that banks can work with the legal marijuana industry without fearing prosecution for such crimes as money laundering.
The Two-Way Justice Dept. Seeks To Expand Clemency For Some Drug Offenders January 30, 2014 Deputy Attorney General James Cole asked lawyers to make their clients aware of new clemency opportunities. By commuting sentences, the Obama administration is trying to correct the different treatment given to crack-cocaine and powder-cocaine offenses.
The Two-Way Colo. Man Files First Challenge To Surveillance Law January 29, 2014 The suit is the first direct challenge to the FISA Amendments Act, the statute the government relies on to collect international communications in bulk.
A marijuana bud and cash at a shop in Denver. An owner of marijuana stores in the city says of his company's bank account, "We treat it like gold." Ed Andrieski/AP hide caption toggle caption Ed Andrieski/AP The Two-Way Holder Favors Pot Banking, And Legal Dealers Shrug January 24, 2014 The attorney general's view could make it easier for marijuana businesses to have bank accounts. But shop owners say they never doubted that banks want a cut of a billion-dollar industry.
The Two-Way Lawyers Seek Justice Department Records On Would-Be Bomber January 13, 2014 Lawyers for a young Portland man convicted of trying to blow up a Christmas tree ceremony are asking a judge to order the Justice Department to open its files and share "facts and circumstances" of electronic surveillance that prosecutors disclosed only months after his conviction.


text:
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Date: 1898
Description: Jacob Gasser family standing in front of farmhouse at Tower Rock Farm.
Date: 1937 ca.
Description: The lawn of the Dell View Hotel.
Date: 1957
Description: Aerial view of the Baraboo Wisconsin Dells airport.
Description: People playing golf on Thomas Ridge at Hillside Home School, an early progressive school operated by Ellen and Jane Lloyd Jones, aunts of Frank Lloyd Wrigh...
Date: 1906
Description: A double exposure of a landscape featuring a very large tree and farm houses superimposed on an image of buildings and crowds at the Sauk County Fairground...
Date: date unknown
Description: Elevated view of House on the Rock. Some of the view is obscured by trees growing in and around the roof of the walkway.
Description: The Dawn Manor, a small "gothic" house on the Dell View Hotel grounds. Also called the Abraham Vand House (later the W.J. Newman House) it was built ca. 18...
Date: 1945-09-27
Description: Three farm wives taking a break at the terrace plowing demonstration and conservation field day on the Carl Ribbke farm near Ableman. From left are Mrs. Ar...
Date: 1952
Description: Wisconsin author August Derleth standing in front of his Sauk City home, "the Place of the Hawks."
Date: 1952-02-13
Description: The Prairie du Sac High School basketball team plays Lodi on Friday night. If the Prairie du Sac team were to win the game, it would share the Tri-County L...
Date: 1883
Description: A group portrait of about 40 members of the Lloyd Jones family. The empty chair in the front row was placed in memory of the wife of Richard Lloyd Jones.
Description: From a portfolio of collotype prints issued in 1900, a sewing class at Hillside Home School, an early progressive school operated by Ellen and Jane Lloyd J...
Description: View across river of Woolens Mill.
Description: Exterior view of the Remington House, located on 2nd Street.
Description: A Mills Violano Virtuoso adds frets and strings to violins. This image was used in the original House on the Rock brochure.
Date: 1925 ca.
Description: Construction workers stand in front of the Butterfield covered bridge.
Description: Women of the Free Congregation (Free Thinkers) of Sauk City, gathered in the basement of their meeting house.
Date: 1910 ca.
Description: Exterior of bark-clad cabin near Devil's Lake. The cabin has wooden steps leading up to the second floor and is surrounded by trees and the lake can be see...
Date: 1911-10-07
Description: Rising waters of the Wisconsin River at the construction site. This view shows the coffer dam, pile drivers, and narrow gauge railroad. Note the partiall...
Date: 1929
Description: View from town of the road leading out of town towards fields and low hills. On the left at the curb is a fire hydrant and a Red Crown Gasoline gas pump. A...
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subset: commoncrawl


text:
PeriwinkleVinca speciesTrees and Shrubs, Plants of Home and GardenCan be grown from seed, though germination irregular: sow shallowly and keep dark until germination occurs. Grows well in even heavy shade; prefers fertile, moist soil. Good ground covers. Easy from cuttings in summer, by serpentine layering, or divide in fall or early spring. Vinca major, the greater periwinkle, is hardy to zone 7-10; Vinca minor, the common or lesser periwinkle, or common myrtle, zones 4-10 See Also Madagascar periwinkle (Catharanthus roseus, Vinca rosea) Related Topics Cuttings
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691 Dudley St Dorchester, MA 02125-2204
This MBTA station is accessible (Accessibility Key)
Parking Spaces: N/A
Average Weekday Availability:
Parking Rate: N/A
Accessible Spaces: N/A
Bike Spaces: N/A
Managed By: N/A
No MBTA parking. Street or private parking may exist.
Commuter Rail Lines
Fare Information
Travel anywhere on the MBTA system for the same price.See all Fares & Passes information.
Transit Mode | Passes / Tickets |
Rail |
$2.25 - $12.50 Zones 1A - 10 $84.50 - $398.25 Monthly Pass, unlimited travel to and from your zone plus travel on all bus, subway and Inner Harbor Ferry. 50% Seniors and Persons with Disabilities |
Bus |
$1.70 CharlieCard $2.00 CharlieTicket / Cash-on-board $55.00 Monthly Bus Pass $84.50 LinkPass - unlimited travel on Local Bus and Subway. |


text:
Let me begin this post by saying while I am all up for breaking records and supporting a good cause, I do not support eating my own kind. Personal feelings aside, I wanted to let you all in on an exciting new addition to this year's Oktoberfest.
Thursday, September 15th, between 3-4pm, The Berghoff will attempt to break the Midwest record to the longest brat and unveil a 45 foot brat. Together with Highland Bakery, Schmeisser's Meats and Sausage, and Halls Rental; Berghoff will go where no brat has gone before. Bites of the brat will be sold as a fundraiser for Mercy Home for Boys & Girls.
In preparation for this amazing feat, Carlyn has so kindly posted the recipe for The Perfect Brat (and no, it is not named after me). But don't eat too many before the big day, save that appetite for bites of the 45 foot brat.
Herman Der German


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Want to know who attends, what topics are discussed, which companies sponsored - or just how last year's event performed? This is the place.
View a quick and easy snapshot of the complete rundown from start to finish of by date and time. Find out when and where you need to be.
See our registration packages and rates. Find out if you're eligible for any discounts. Check out our upgrades and ancillary products.
CLICK HERE for a short video from the 2016 opening session to help get you ready for this year!
View our conference program and see what makes us so great each and every year!
Whether you're crossing oceans or crossing the street, buttoned-up travel plans are a must. Get all you need to know about the trek - right here.


text:
This is an early grammar for elementary learners of English. The units are divided into two sections: the first explains form and structure; the second concentrates on functions performed by structures. The book contains various conversational examples of the structures covered.
"synopsis" may belong to another edition of this title.
Book Description Book Condition: Brand New. Book Condition: Brand New. Bookseller Inventory # 97801395266401.0
More Information About This Seller | Ask Bookseller a Question


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Dance Review: "Studio Three: New Works Festival"
Read More: Richmond Ballet, Studio Three
Richmond Ballet's "Studio Three: New Works Festival" features four up-and-coming, innovative choreographers showing original works. All four pieces in the Studio series are very diverse, and really show what these supremely talented dancers are capable of.
The first piece, "The Edge of Place" with choreography by Amy Seiwert and featuring music by Hildur Guónadottir, has the female dancers being moved at times like dolls by the male dancers. The movements are rigid and mechanical while simultaneously being very graceful and peaceful. The piece was almost reminiscent of Kabuki theatre with the strong contrasting colors of red and whites in the dancer's costumes.
The second piece, "Dominant Curves" choreographed by Sasha Janes and music by Osso and Sufjan Stevens, evokes the feeling of watching animals on the Serengeti. "Curves" really highlights the athleticism of the dancers as they move together channeling the graceful lengthening movements of exotic wild animals. The costumes are beautiful navys and purples creating the illusion of a night time scene.
The third piece, "Vanish" choreographed by local talent, Starrene Foster, and with music by Gavin Bryars, has an almost haunting feel to it. The movement in the beginning felt zombie-like. Out of the four pieces I saw on Friday, "Vanish" elicited the most emotion. With costumes in tones of gray, slate, and white, there were times when the dancers almost looked like tombstones placed around the stage. While the piece could translate as a bit macabre, I found it to be overwhelmingly beautiful. Foster's choreography is organic and the dancers are perfectly in sync.
The final piece, "Saideira" is choreographed by Darrell Grand Moultrie with the exciting and fast paced music of Rodrigo y Gabriela as the backdrop. I really enjoy Moultrie's idea of having the dancers being able to dance, let loose and just have fun while not necessarily having a plot behind the piece. However, I did find the piece to be a bit too chaotic and it also felt very long, possibly because there was no order to the dance.
As with most of the Studio series, there are videos featured in between the works, where the choreographers explain their creative process and give the audience some insight into the piece they are about to see.
"Studio Three: New Works Festival" has performances through April 14th at the Richmond Ballet's Studio Theatre.
Do be sure to join Richmond Ballet for "Out at the Ballet" on April 10th at 6:30p.m.
www.richmondballet.com for information.
Jen Maciulewicz is theatre critic for GAYRVA.com and is a Richmond local. Jen attended VCU and holds a B.S. in Anthropology. She has starred as Reno Sweeney in Cole Porter's "Anything Goes" and attended VCU's School of Music. Follow Jen on Twitter at www.twitter.com/jenlaumac.
Related Stories
Richmond Ballet premieres three-show residency at Carpenter Theatre this weekend
Richmond Ballet introduces "Trio", an iconic performance of three shows in one night on November 4-6 at the Carpenter Theatre at the Dominion Arts Center. "Trio" will feature The Kingdom of the Shades from Marius Petipa's classic full length ballet, "La Bayadiere", George Balanchine's "Slaughter on Tenth Avenue", and Ma Cong's "Lift the Fallen". This [...]
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I notice that Wilson Champions Choice hybrid set with gut and ALU rough is not listed for sale anymore at TW. Does anyone know whether it will be back or what happened? Thanks, Harry
It seems it's on some serious back order with wilson but the strange part is that TW took champions choice off their site. The good thing is that you can still buy lux alu rough and pacific tough gut and that is the same as champions choice.
For whatever reason, when TW doesn't have an expected date, items are removed from the web site. This doesn't mean it's no longer available, it just means TW doesn't have a date in the near future.


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can you believe that next week my life will be over and so will season 3 of skam and i will forever be in a state of numbness bc
on the one hand i will be so happy to have gotten to witness this entire series in real time whilst making the BEST memories along the way on this whole epic journey of isak and even's as both individual characters and together as a couple
but i'll also be in a constant state of mourning bc i KNOW that NO OTHER show will ever meet this intangible standard that skam has set, ever, to fulfill every deep need of mine i have ever wanted to see be depicted on a tv show in such a REAL form and be represented SO ACCURATELY. no other show is just gonna do it for me now? how do i move on now? how do i go back to life without skam until season 4 now? what am i gonna do?
ugh this is so bittersweet bc this HONESTLY is a case of "i know you're gonna end, and i know you have to end, because all good things come to an end … but i don't want you to end and go because … you've been so good to me. so good to me."


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How to Launch a Product Online With a Number of Methods
Executing on a successful product launch is essential for starting your product off with a bang and improving upon your product's perception. You can manufacture and create buzz about your product through a successful product launch, thus attracting more affiliates and improving your product's conversion rate.
In this article we're going to address how to launch a product online with several effective strategies.
The Countdown
Creating a countdown for your product is a great way to create buzz. Make sure that when you're using the following traffic methods that in the weeks leading up the official launch that you're revealing more and more information about your product and reminding them about the countdown/launch date.
Whenever someone sees that there is a countdown associated with a product launch, the implication is that this is something worth waiting for and following along. It substantially increases the perceived value of your product to no matter who reads about it, so create your release date and let the countdown begin.
Email Marketing
Email marketing is your best friend when it comes to launching a new product. I'm not just talking about interacting with your own list, but pursuing a solo mailing or ad swap is a great way to reach an entirely new and targeted audience, particularly when you're ready to launch a new product.
Write up a very attractive sales pitch for your new product and pay to blast that offer out to someone else's sizable list or swap lists with someone in exchange for mailing your list about that other webmaster's offer. You can do this either to potential customers of your product or to potential affiliates of your product.
Forum Marketing
Hit up influential blogs in your niche and use them to build the buzz on your product. Put information about your product launch in your signature/profile information and keep it updated to reflect the countdown to your product's actual launch date.
PR Sites
PR sites are an obvious choice whenever you want to promote anything new. This gets the word out about your product and can help to spread some buzz as people see and share that press release.
Online Advertising
AdWords, Facebook Ads, and similar advertising networks are great ways to reach targeted audiences to promote your product to. Facebook Ads specifically enables you to get ridiculously targeted to find your exact customer base so that you don't waste a penny in advertising costs without converting on that traffic.
Group Buying Sites
Heard of sites like Groupon and Living Social? Millions of people regularly peruse these sites looking for deals on interesting products and services. If your offer can be presented at a special discount tier, these sites can be a gold mine for getting lots of opting in customers.
Guest Blogging
Guest blogging is a great way to look like an authority on a particular topic and build credibility so that people will be more inclined to check out and purchase or promote your product. Convince (or pay) another webmaster in your niche to let you hop on their blog and make your own informational post one day which relates to your product, then sneak in info about the launch.
Affiliates are the lifeblood of any successful product launch. Whenever you're using any of the above traffic sources that you mention about the affiliate program to go along with your product. Check out my post on how to get affiliates for more information on how to do just that but just as importantly check out this post on how to screen affiliates to learn how to sift through those affiliates who aren't worth your time and ensure that you only have the best promoting your product.
Source: EzineArticlesArticle Tags:
How To Launch A Product Online
Hence the professional search engine services are very beneficial and also help to increase traffic and clients on your site. This is also helpful to attain target and increase sale. Is you have
Some people are still unaware about how helpful the redesigning of website can be for them. In order to have a better understanding, these people should have clear knowledge the importance of website
If you use SEO, Montreal is a great location for tapping an online audience because of the city's sophisticated business landscape. For your small Montreal business, maximizing your blog's visibility
As it is a well known fact that website development carries big dream of people; it is none other than revenue generation quickly. Although many people fantasize that creating and building website
Today everybody is after a successful business and to make a business successful one goes to any length resorting to different tactics. If anyone has an online business, he must be trying best to
Website development has transpired as an industry in the last decade. A company or a person develops web sites to be placed on the World Wide Web in the field of web development. Here Helena tries to
American tech entrepreneur Eric Ries insists "Success can be engineered by following the right process." As start-ups are a dime a dozen and such a large portion of new online businesses fail in
Online advertising within the fashion retail industry is bigger than it has ever been before. With all the different social media networks, blogs, article websites, picture posting and all the other
Business strategy can also be referred to as a suitable game-plan that is specifically designed to reach certain pre-defined goals & objectives. The two most important stages of a well-designed
If you are launching a product you want to be noticed, think visual! Pinterest, Tumblr and other channels will help you find an audience.
Cloud backup, as the name implies, is a kind of backup plan that is used to store data and information in the 'cloud' or in a remote server, other than the computer itself. In the cyber world, this
Today, if you asked MBA students to discuss a successful product launch, they would probably give you a case study with one of Apple Corporation's most recent products. Even with the passing of Steve


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Try the Truck Wizard
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6304 North 10th St
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The stars of the main page are arranged vertically by their
colors (from blue to red) and temperatures (from about 50,000
Kelvin to under 3000 Kelvin) according to their spectral classes. Go to the table to see how class,
temperature, and color relate to one another. The stars are
arranged horizontally according to their luminosity classes, that is,
according to whether they are main sequence "dwarfs", giants, subgiants (which fall
between the dwarfs and giants), supergiants, or bright
(which fall between the giants and the supergiants). With one
known exception, class L is a mixture of
low mass dwarfs and brown
dwarfs, while T stars are all brown dwarfs. If the
components of a double or multiple star are significant and
highlighted in the star's story, each is listed
seperately. Carbon stars,
class C, for which carbon exceeds oxygen in abundance, and class
S, for which they are about equal, are listed at the end of the
main table.
Each star in the table is introduced by its MKK class, which consists of
its decimalized letter class (in which the broad classes are
subdivided 0 [zero] through 9 from warmest to coolest) followed
by a Roman numeral that gives the luminosity: I through V for
supergiant, bright giant, giant, subgiant, and dwarf. Ia
supergiants are more luminous than Ib supergiants; "0" ("zero")
as a luminosity class stands for "hypergiant," a star more
luminous than a supergiant. Hypergiants are included with Ia
supergiants. Stars with "p" for peculiar or "m" for "metallic
line" cannot be simply classified. Brown dwarfs are referred to
as "BD," while "pms" indicates a not-quite-stabilized "pre-main
sequence" star (a "protostar".
Separate tables at the end list white dwarfs, neutron stars, black holes, and various
kinds of variable stars.
You can find many of these stars on this classic HR diagram.
AB Aur | 30 Tau B |
Alpha CMa B | Alpha CMi B | Alpha Leo Ab | Omicron-2 Eri B | 14 Aur Cb | 16 Dra B |
X Per-B |
Cyg X-1 | V Pup |
Alpha UMi | Beta Dor | Delta Cep | Eta Aql | Kappa Pav | l ("el") Car |
FF Aql | RR Lyr | S=10 Sge | V1334 Cyg | U Aql | W Sgr |
X Sgr | Zeta Gem |
Chi Cyg | Omicron Cet | R Hya | R Leo | R Lep | U Ori |
Delta Sco | Eta Car | R CrB | T CrB |
Mu Eri | Nu Eri | Tau Her | Zeta Cas | Zeta Peg | 3 Vul |
53 Per |
Gamma Dor | Gamma Ser | Iota Vir? | HR 4686 UMi |
Alpha Cen C | Alpha Gem C | 40 Eri C | V1200 Oph |
Alpha Vir | HR 6535 Sco | Pi-5 Ori | T CrB | 2 Lac | 35=UU Psc |


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Disaster Recovery and Business Continuity for Cloud Services
Cloud Computing Disaster Recovery
Disaster Recovery and Business Continuity for Cloud Services News
March 10, 2017
AWS S3 outage: Channel partners mull redundancy options
Channel partner executives and industry observers consider redundancy options in the aftermath of Amazon Web Services' recent Simple Storage Service outage.
November 22, 2016
Case closed: Law firm selects iland DRaaS for faster, easier DR
Minutes count in legal work, and Graubard Miller needed a simpler platform for disaster recovery. The verdict: The law firm chose iland disaster recovery in the cloud.
October 28, 2016
Dell Services elevates Alabama city's DR plan with the cloud
After a massive tornado touched down across the state, the city of Opelika, Ala., looked to the cloud to get its IT infrastructure up and running in case of disaster.
May 31, 2016
Sneak peek: Zerto DR application detailed by vendor's VP of product
Zerto's mobile disaster recovery app, one piece of the vendor's next release, allows customers to check on their business continuity environment from anywhere.
Disaster Recovery and Business Continuity for Cloud Services Get Started
Bring yourself up to speed with our introductory content
disaster recovery as a service (DRaaS)
One approach to a strong disaster recovery plan is DRaaS, where companies offload data replication and restoration responsibilities to a third-party provider. Continue Reading
Partners retool per-gig BDR services, software pricing model
Faced with an unsustainable per-gigabyte backup and disaster recovery pricing model, channel partners explore and implement new pricing strategies in hopes of making a profit. Continue Reading
Cloud disaster recovery guide: The value of DRaaS
DR as a Service enables providers to offer a more affordable alternative to conventional DR services. Find out how to get started with this disaster recovery guide. Continue Reading
Download: How to thrive in a cloud ecosystem
In this 17-page guide, learn how to tackle the top challenges that occur in cloud ecosystems, take a closer look at specific ecosystems and partnering considerations and realize how to verticalize your offerings to specific industries.
By submitting your personal information, you agree that TechTarget and its partners may contact you regarding relevant content, products and special offers.
You also agree that your personal information may be transferred and processed in the United States, and that you have read and agree to the Terms of Use and the Privacy Policy.
Evaluate Disaster Recovery and Business Continuity for Cloud Services Vendors & Products
Weigh the pros and cons of technologies, products and projects you are considering.
Enhance cloud resiliency with proper data management
Explore factors that can influence your level of cloud resilience, such as outages in different geographic locations, and the importance of positioning data for quick recovery. Continue Reading
Match disaster recovery as a service providers to business needs
DRaaS vendors must do more than make your data available in a disaster. The specifics of how their recovery works can determine if a vendor is right for your organization. Continue Reading
Implementing cloud recovery services: Take advantage of accessibility
Cloud disaster recovery is a boon for SMBs and other businesses that may have previously been scared off by the cost and complexity of DR. Just use caution in picking a provider. Continue Reading
Manage Disaster Recovery and Business Continuity for Cloud Services
Learn to apply best practices and optimize your operations.
Cloud data recovery: Documentation is the key to success
In creating a plan for data recovery in the cloud, it's important to keep track of your infrastructure, DR requirements and the potential duration of failover. Continue Reading
Syncplicity opens cloud file management software to channel partners
Cloud-based file management provider Syncplicity unveiled its channel program with discounted pricing for initial orders and renewals, and admin controls. Continue Reading
Managed backup services: Pros and cons of hosting approaches
There are two basic approaches to providing managed backup services: reselling services from another provider or, for brave and deep-pocketed providers, building your own NOC. Find out the pros and cons of each approach. Continue Reading
Problem Solve Disaster Recovery and Business Continuity for Cloud Services Issues
We've gathered up expert advice and tips from professionals like you so that the answers you need are always available.
Using metro storage clusters to manage data growth, add value to IaaS
Metro storage clusters -- geographically distributed, interconnected storage platforms -- can help IaaS providers manage data growth and add value. Continue Reading
What are the main challenges associated with DRaaS SLAs?
Cloud providers must cover security, access control and restoration time when negotiating DRaaS SLAs with customers, says cloud expert Mooney Sherman. Continue Reading
Disaster recovery in the cloud: What do customers expect in an SLA?
Crafting an SLA for DR in the cloud requires providers to address several issues up front with customers, according to cloud expert Mooney Sherman. Continue Reading


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What is it/what does it do?
You don't even need to click through to the product's website, I have produced a summary of what they say about themselves here:In the next 60 seconds – gain access to a work-at-home program paying as much as $87 an hour
- Limited Number of Positions, Check Availability in Your Area.
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Is anyone buying it?
Here I can provide you with some hard facts. We can turn to statistics provided by the payment processor. They release something they call the product's "Gravity". It's an indicator of a product's sales rank. I've processed this figure and produced a rating out of 100. Products with a high rating are popular. Autopilot Income System scores 61.43/100 which is around standard.Your buying options
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You click on the following link to https://autopilotincomesystem.org/?cb=1&hop=0, and look for their link to buy the product. From there you'll be linked through to the payment processor page and you can pay with a credit/debit card or PayPal. As of the time of writing this review the standard price for the product is $97.Option 2: Buy Through My Link
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Mellanox MSX6002TBR SwitchX 36 port FDR-10 40GigE VPI Spine (MPN:MSX6002TBR) is a 36 port FDR-10/40GigE VPI spine for SX65xx chassis switches with RoHS-6 compliant.- Technical Specs
Learn more about Mellanox MSX6002TBR SwitchX 36 port FDR-10 40GigE VPI Spine
Specifications Manufacturer Mellanox Technologies Model MSX6002TBR Type Switch - 36 Ports
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RoHS-6 - Return Policy
Limited Replacement Return Policy- Return for refund within: non-refundable
- Return for replacement within: 30 days (no return shipping provided)Products eligible for replacement must be returned to SabrePC within 30 days of the invoice date for this policy to apply. Products covered by this return policy may only be returned for a replacement of the same or equivalent item, if the original is no longer available. "Return" constitutes receipt of the product by SabrePC, and not the mere issuance of an RMA - Customer Review
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THE WORLD HAS BEEN INVADED BY ALIENS! It's up to a nerdy, lazy high school kid to save it!
3.82 / 5.00 7,916 ViewsA gorgeous and artistic first person adventure, from start to finish.
Clip -Prologue- is a true experiment for me, first started as an art picture, continued to be so much more.
This is the first of many, many parts to come for this series, this is mainly due to the giant size created with the art style I have in mind.
To let you guys know how huge this little thing is, its a whopping 10 megs, mainly due to the art, its quite shocking something this short, has been such a big piece of my time.
It was started, June 14th, 2008, and was completed, January 15th, 2009.
It was beta tested prior to release, but if you spot any bugs, be sure to PM me about it.
I hope you enjoy the game.
Thank you all!
wait a minute.
in the instructions u said the main character's name was ali right?
thats my name, anyway its a great game but really short even for a prologue,
maybe try and lower the quality of the art and sound to fit more in.
Haha, thats a very neat coincidence!
i also loved the techno remix of the portal credits!
Haha, thanks, I thought it would be a perfect modern ending to it.
IDK wat all these people are saying, or can't they read. Because it says PROLOGUE! That means this is like a preview.
Thanks man, glad to see a couple people understand.
Whoaaoww!! Oh darnnn...
So short!!
Great gameplay, both smooth a responsive.. It's only too short, me wants more, almost can't wait to see the full game.
Great effort, great result... This is why I love visiting NG. Easily: 5/5 10/10
Thank you so much!
This is why I love making games, to hear the praise from others, and to know that my hard work was put to good use!
I hope to see more of these
Thank you very much, and your wish is my command.


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Diversity in the IT Industry is Key to Solving Global Problems
Corporate Social ResponsibilityThis blog post was guest-written by Nora Ayanian, Assistant Professor and Director of the ACT Lab at USC. She'll be guest-speaking during the "Meet the Amazing Women Using Technology to Change the
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G.U.N.T.H.E.R Care for Customer Care, Beyond Robotic
CollaborationSome of the most iconic characters in movies and television haven't even been human. For example, most people don't realize the name of the robot on Lost in Space was
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Making the Factory of the Future a Reality with FANUC
ManufacturingFANUC announced a collaborative effort with Cisco, Rockwell Automation, and Preferred Networks (PFN) to jointly develop the FANUC Intelligent Edge Link and Drive (FIELD) system.
Read More -
The Workplace of the Future: Connected, Collaborative, Creative
Digital TransformationThe Internet of Everything is reshaping every aspect of our lives—including how and where we work. Think back to the 1950s, when the telephone was the only connected device in
Read More -
Cisco's Chief Futurist Shares Top 5 Predictions for 2013 and Beyond #IoE
The PlatformThe future intrigues us all, especially when every now and then we're able to catch a glimpse of what's to come. At Cisco, one of the ways we build our
Read More


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OMG- is San Cristobal de las Casas the cutest place evar? I'm here with Moya and both of our Cute-dars are worn out from overuse. There are the cute colorful buildings, the cute little courtyards you can peek into and see little gardens and sleeping dogs, and the cutest of all- little indigina abuelitas who are like four feet high carrying adorable laughing babies in slings around their neck. Does this sound patronizing? I don't care, yesterday I saw an old woman walking her 7 year-old son home from school and they were the same exact height! I nearly died from a cute-attack.
Here are the photos:
La Calle es Nuestra- Da Streetz is Ourz! (Ladies!)
I didn't know which haircut to choose..
This guy has got G.O.A.T. status! "I don't walk, I get carried."- Old Dirty Bastard, R.I.P.
Actually this was from the Museum of Mayan Medicine, so it could be that the dude is just sick. The museum is a reccomendation, by the way.
It's considered rude to photograph Indiginous people, so I didn't get many good shots of their colorful clothes and delightful babies.
Glamorous times in San Cristobal
We cooked back at the hostal all the things we got at Merket. Some kind of white fish, beautiful little multicolored chiles, mango, lime, cilantro and green tomatillos, wrapped in little packets.
This photo didn't come out, but with some sauteed Swiss Chard and piping hot fresh tortillas, this meal was binoculars.
Cafe life with the German girls.
On the left you can see one of Patricia's patented "adorable" faces.
Fruit salad on the street, 10 peso breakfast
Taco Heaven in the San Cristobal Markets
If you want your coke to go... you got to bag it up!
Yoga time to offset the monumental food fest we'd been having.
San Guadalupe.
We went to Las Grutas, which is a cavern 10 miles outside of town, and had a picnic.
Aguacate, Jamon Serrano y Queso Gouda- these sandwiches were legendary.
Having a total juice-box moment.. what a dork
Good picnic.
Check out the Chino and Negro masks up there! Anybody want one of these as gift back home?
We went to a Thai-Indian restuarant run by a Mexican Sikh, and this guy was singing an accoustic cover of "Unbelievable" by EMF! It was unbeli-- well, you know.
So, what is Pad Thai made by a Mexican Sikh like? Well, it not like anything else, but it was a nice respite from tortilla-and-meat combos.
Our Shrine.


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Crocodile attacks handler and pulls him into the water
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Naga Hills rugs in cream have been hand loomed in India with a 100% undyed natural wool yarn which creates subtle colour variation on the soft and luxurious pile. A skilfully hand carved border provides extra dimension and gives this rug the ability to make a statement or to fit naturally into a wide range of interiors, both contemporary and traditional.
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$ 10.00
This stainless steel ID tag has a red medical symbol on the front and attaches to any of our custom made bracelets. This medical tag measures 1 1/2 x 3/8 inches.
This slender medical ID bracelet can be engraved to fit your needs. On the front you can have up to 4 lines of information, each line can have up to 18 characters (this includes spaces). The back can also be engraved, add up to 4 lines of information, each line can have up to 25 characters.
For example: Madelyn H Smith = 15 characters (letters and spaces)
Because of the custom and very personalized nature of engraving, custom jewelry cannot be returned or exchanged.
Please allow approximately 2 weeks for delivery.


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There was a time when being a musician meant being a performer. The two words were interchangeable. And in that time, to be a good performer meant internalizing the mood, the melody, the pain, the joy, and the ecstatic orgasmic release that sometimes only music can provide an inward traveler. If you think back on whom the great performers of pre-war America were, the names read like a roster of murderers and malcontents, disturbed individuals who knew only their instrument as a means to express the isolation they felt inside. For, in those dusty days, the musician was not the respected, mythologized artisan that he is today. The musician was the outcast — the slightly cracked, socially incapable, wandering loner who couldn't hold down a job, a lover, or even a friend. These wayward daydreamers were cast to the fringes of society, only to be respected decades down the road when they emerged from the blast furnace of isolation with a repertoire of raw, unfiltered songs that smoldered from the core of their being. Son House, Leadbelly, Lonnie Johnson, Mississippi Fred McDowell, Dock Boggs, Roscoe Holcomb: these were not delicate men. If you walked into a bar while Son House was playing, you wouldn't wax poetic (like I am now) about the emotional honesty of the performance — you'd be downright frightened. But in that moment of fear, you'd recognize his pain in yourself and that would be the root of your fear. And you wouldn't stop listening until the last note was played.
When I saw Frank Fairfield performing at 3 Clubs in Los Angeles some weeks ago, I knew I was hearing something that I hadn't heard, or felt, before. Here was a young man with a banjo, a parlor guitar, and a side-saddle fiddle playing songs that hadn't been sung — and certainly haven't been in vogue — in decades. In his quivering voice and his relentless, brutal attack on his instruments, I stood witness to the type of performer who earned his stripes on the stage and on the street. Not in pro-tools. Only just recently has he released his first mp3 (a live recording, aptly enough) for us to enjoy. More, Robin Pecknold of Fleet Foxes was duly impressed and invited Frank to open for him on their upcoming tour of the United States. Enjoy the track, but please don't miss a chance to see Frank live if you can.
[ stream ] Frank Fairfield – Mole in the Ground
Bascom Lamar Lunsford – Mole in the Ground (original)
or [ download ] Frank Fairfield – Mole in the Ground


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Effortless Eater Kid's Cook-off: The results are in!
By Melissa Ford
Have you ever watched Masterchef, Iron Chef or Chopped, those amateur cooking challenges on TV? No need to turn on the tube to catch the latest in culinary challenges because we have our very own: Effortless Eater Kid's Cook-off! This event brought kids from ages 5 to 9 out on a rainy August day to Dominican University's Jay W. & Doris K. Christopher Nutrition Science Center for some seriously fun competition!
These budding culinary talents had one intention - to show off their skills in the kitchen!
Skills and enthusiasm they displayed. Bernard Jean-Simon, dad of contestant Emelie Jean-Simon, reported, "My daughter left the house a bit nervous but when she came home she had a new light of excitement for cooking; this was a great event!"
First place winner, Nicholas Rosenbaum, wowed the judges with Ahi Tuna Poke topped with a micro green and Hearts of Palm salad in a white miso butter vinaigrette garnished with avocado, tobiko, micro shiso and enoki mushrooms. Pretty impressive fare! When Nicholas was asked how he felt while creating the winning dish, he replied, "I was really confident and stayed focused while preparing my meal."
Effortless Eater Kid's Cook-off is the brainchild of Angela Douge MPH, RD, LDN, who has taken her love of cooking and turned it into a community kid-friendly event! Why is she so passionate about kids creating in the kitchen? "Cooking with my son has shown me another way to make life long memorable moments, which I believe will be valuable to his health in life."
Douge plans on making this competition an annual event so get busy with your child - mixing, beating, experimenting, and honing that special receipe in the kitchen, but more importantlly, making delicious life long memories!
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Melissa from OakPark.com/EmpoweredParent
Posted: August 22nd, 2011 6:30 PM
What a great way to help your child develop proficiency in the kitchen AND encourage a healthy lifestyle! Thanks, Angela!
Angela from Oak Park
Posted: August 22nd, 2011 9:52 AM
All those families out there with kids that can cook, be on the look out for us next year!
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text:
Publication number | US6541256 B1 |
Publication type | Grant |
Application number | US 09/913,218 |
PCT number | PCT/US2000/003531 |
Publication date | Apr 1, 2003 |
Filing date | Feb 11, 2000 |
Priority date | Feb 11, 1999 |
Fee status | Lapsed |
Also published as | WO2000047040A1 |
Publication number | 09913218, 913218, PCT/2000/3531, PCT/US/0/003531, PCT/US/0/03531, PCT/US/2000/003531, PCT/US/2000/03531, PCT/US0/003531, PCT/US0/03531, PCT/US0003531, PCT/US003531, PCT/US2000/003531, PCT/US2000/03531, PCT/US2000003531, PCT/US200003531, US 6541256 B1, US 6541256B1, US-B1-6541256, US6541256 B1, US6541256B1 |
Inventors | Ko-Hua Chen, Nancy C. Joyce |
Original Assignee | The Schepens Eye Research Institute, Inc. |
Export Citation | BiBTeX, EndNote, RefMan |
Patent Citations (6), Non-Patent Citations (1), Referenced by (5), Classifications (18), Legal Events (6) | |
External Links: USPTO, USPTO Assignment, Espacenet | |
This application claims the priority of U.S. Provisional Patent Application No. 60/119,788 filed, Feb. 11, 1999 entitled GROWTH MEDIUM FOR HUMAN CORNEAL ENDOTHELIAL CELLS, the whole of which is hereby incorporated by reference herein.
Part of the work leading to this invention was carried out with United States Government support provided under Grant No. NEI R01 EY05767 from the National Eye Institute. Therefore, the U.S. Government has certain rights in this invention.
Corneal endothelial cells are different from vascular and pulmonary "endothelial cells" as they have a different embryonic tissue origin. Human corneal endothelial cells do not normally proliferate in vivo to replace those lost due to cell injury or death. Growth of these cells in culture is also extremely limited. This can be a serious problem as age, diseases such as glaucoma and diabetes, and ocular surgical procedures, such as laser vision correction and cataract extraction and intraocular lens implantation, cause an accelerated loss of these precious cells. There are no medical treatments for corneal diseases resulting from endothelial cell loss. Currently, corneal transplantation is the only way to restore normal vision.
The relative ability of corneal endothelial cells to proliferate in vivo and in culture appears to be a function of age; i.e., embryonic corneal endothelial cells and cells from neonates will proliferate much more readily than cells from children and adults. In a few cases, researchers have been able to culture cells from older donors, but growth has been supported by seeding the cells onto an artificial matrix, such as chondroitin sulfate/laminin, or onto extracellular matrix secreted by corneal endothelial cells from cows, one of a number of species whose corneal endothelial cells do grow readily in culture. A reliable way of supporting cell culture of human corneal endothelial cells would be highly desirable.
A new formulation for a culture medium that can be used to overcome such difficulties has now been developed. In general, the invention is directed to a formulation for a growth medium for culturing cells of neural crest origin, most preferably corneal endothelial cells, or for accelerating the growth and proliferation of such cells. The formulation for the nutrient medium of the invention includes nerve growth factor, preferably at a concentration of 1-100 ng/ml and most preferably 20 ng/ml. The growth medium formulation preferably also includes epidermal growth factor (preferably at a concentration of 1-200 ng/ml and most preferably 5 ng/ml). Most preferably, the formulation of the invention also includes fibroblast growth factor, at a concentration of 5-400 ng/ml or, most preferably, 40 ng/ml.
A commercial growth medium, particularly a serum-free medium, forms a useful basis for the growth medium of the invention. The growth medium of the invention can be augmented with serum, e.g., fetal bovine serum, as needed. As is well known to cell culture specialists, a useful human cell growth medium preferably also includes added ascorbic acid, human lipids, antibiotics and cell viability stabilizers.
Other features and advantages of the invention will be apparent from the following description of the preferred embodiments thereof and from the claims, taken in conjunction with the accompanying drawings, in which:
FIG. 1 is a cross-section of a cornea showing the orientation of the corneal layers;
FIGS. 2A and 2B are micrographs showing comparative examples of the growth of human corneal endothelial cells from older donors using a prior art formulation (FIG. 2A) and the growth medium of the invention (FIG. 2B);
FIG. 3 is a bar graph showing cell density of transplanted corneas. A line drawn at 500 cells/mm2 indicates the cell density below which there are insufficient cells to maintain corneal clarity;
FIG. 4 is a graph showing pachymetry of transplanted corneas after ouabain treatment following 14 days in organ culture to illustrate that transplanted endothelium is functional; and
FIGS. 5A and 5B are micrographs comparing the morphology of normal and transplanted human corneal endothelium.
The cornea is the "window" of the eye. Because it transmits light into the eye and protects the eye from the environment, normal vision requires a clear cornea. Corneal clarity results from the specific arrangements of fibrils in the stromal layer (see below) that permit light to be transmitted through the cornea rather than to be absorbed. If water is present in the stroma in excess amounts (corneal edema), the arrangement of these fibrils is disrupted, resulting in corneal clouding and loss of visual acuity.
As shown in FIG. 1, the cornea consists of four major layers. The epithelium is the outermost layer of the cornea. It is 5-7 cells thick and protects the eye in a manner similar to that of skin. It is bathed on the outside by tears. The stroma is the thick, gel-like middle layer that contains numerous long filaments separated from each other by molecules which tend to attract water. These filaments are precisely arranged to let light pass through the cornea without being bent or absorbed. The stroma also maintains the cornea in the curved shape required to focus light on the lens and the retina.
Bordering the interior of the stroma is a thick acellular layer known as Descemet's membrane. Endothelial cells secrete the gel-like material of this layer, and the composition of this layer differs from that of the stroma. Descemet's membrane is the substrate to which the endothelial cell layer is attached. The endothelium forms the innnermost layer of the cornea and is just one cell thick. The base of this cell layer is attached to Descemet's membrane and the surface is bathed by aqueous humor, the nutrient fluid that occupies the anterior chamber of the eye.
The cornea does not contain blood vessels and, as is such, nutrition of the corneal tissues occurs through both the ocular surface (which supplies the majority of oxygen) and the aqueous humor (which supplies all other nutrients). Cells of the endothelial monolayer permit slow percolation of aqueous humor through the intercellular spaces into the stroma, but the arrangement of these cells is sufficiently tight to form a barrier to prevent excess fluid from entering the stroma. Endothelial cells also contain an "ionic pump" in their plasma membrane that actively removes excess water from the stroma and returns it to the aqueous humor.
In spite of their importance in maintaining normal vision, corneal endothelial cells do not divide to replace dead or injured cells. So, throughout life, human endothelial cells are lost but not replaced. Instead, the remaining cells enlarge to cover the area formerly occupied by the dead or injured cells. As humans age, this gradual cell loss and enlargement of the remaining cells can cause breakdown of the endothelial barrier. In addition, diseases such as glaucoma and diabetes, and ocular surgical procedures, such as laser vision correction and cataract extraction and intraocular lens implantation, cause an accelerated loss of these precious cells. When cell density is reduced below a critical number (e.g., 500 cells/mm2), water enters the stroma and disrupts the filament arrangement. This disruption causes the cornea to become cloudy. The visual loss resulting from corneal clouding is a form of blindness. Light can be perceived, but images are blurred, giving the appearance of looking through a dense fog. There are no medical treatments for corneal diseases resulting from endothelial cell loss. Currently, corneal transplantation is the only way to restore normal vision. The growth medium of the invention makes possible important new approachs to correcting these problems.
The optimal formulation of the growth medium of the invention was determined by dose-dependent testing of each ingredient on the viability and/or 3H-thymidine uptake (a measure of DNA synthesis/proliferation) of cultured rat corneal endothelial cells (a species whose cells grow well in culture). As the formulation developed, it was used to culture corneal endothelial cells from adult (>50 y.o.) human donors. For this culture, Descemet's membrane and attached endothelial cells were mechanically stripped from the donor cornea. The resulting tissue pieces were incubated for 1 hour in 0.2 mg/ml ethylenediaminetetraacetic acid (EDTA) to remove endothelial cells from Descemet's membrane. After centrifugation, the isolated cells were placed in 6-well tissue culture plates and incubated in culture medium at 37� C. in a 5% CO2 humidified atmosphere. Medium was changed every other day. Cultured cells reached confluence in 7 to 14 days.
Prior to the development of this formulation, studies were conducted to test the ability of adult corneal endothelial cells to grow on an artificial matrix (1% chondroitin sulfate/1% collagen) and on bovine or rabbit corneal endothelial cell matrix. Better growth was obtained on the artificial matrix, but cell shape frequently differed from normal. Once the preferred formulation of the growth medium was determined, it was possible to grow cells from older adult (>50 y.o.) donors is directly on tissue culture plastic and still have them retain their normal polygonal shape. Thus, the use of the growth medium of the invention does not require coating the plastic with either artificial matrix or cell-derived matrix as is required by prior art formulations. FIG. 2 shows the results when endothelial cells from older corneal donors were cultured for the same period of time in either Medium 199 (GIBCO/BRL) supplemented with 10% fetal calf serum and 1% chondroitin sulfate and plated on a 1% collagen matrix (A) or were cultured with the growth medium of the invention on tissue culture plastic (B). Cells in (A) exhibit a lower density and abnormal, elongated morphology. Cells grown in the growth medium of the invention grow to a higher density and exhibit normal, polygonal morphology.
The preferred formulation of the growth medium of the invention has the following composition:
1. OptiMEM (containing insulin, transferrin, and selenium)—OptiMEM is a commercially available serum-free medium.
2. 8% fetal bovine serum (Hyclone) preferred range 125%.
3. 20 μg/ml ascorbic acid (Sigma)
4. 0.005% human lipids (Sigma)
5. 40 ng/ml fibroblast growth factor (pituitary) (Biomedical Research Technologies)—preferred range from 5-400 ng/ml
6. 5 ng/ml epidermal growth factor (mouse)—(Upstate Biotechnologies)—preferred range from 1-200 ng/ml
7. 20 ng/ml Nerve Growth Factor—(Biomedical Research Technologies) preferred range from 1-100 ng/ml
8. 0.08% chondroitin sulfate (Sigma)
9. 200 μg/ml calcium chloride (Sigma)
10. 50 μg/ml gentamycin (GibcoBRL)
11. RPMI-1640 Multiple Vitamin Solution- {fraction (1/100)} (Sigma)
12. Antibiotic Antimycotic Solution- {fraction (1/100)} (Sigma)
The growth medium of the invention differs from prior formulations in a number of specific ways. For example, the base medium used in the preferred formulation, OptiMEM (GIBCO/Life Technologies), contains ingredients important for supporting cell proliferation, such as insulin, transferrin, and selenium. Other nutrient media containing these three ingredients could substitute for OptiMEM. The growth medium of the invention also contains nerve growth factor, which is generally not included in culture media. Preferably, the medium of the invention contains a combination of nerve growth factor (NGF), epidermal growth factor (EGF) and fibroblast growth factor (FGF). Additionally, the preferred FGF concentration, at 10 ng/ml, is significantly lower than the 400 ng/ml FGF concentration in other conventional media, e.g., Englemann's medium.
The following example is presented to illustrate the advantages of the present invention and to assist one of ordinary skill in making and using the same. It is not intended in any way otherwise to limit the scope of the disclosure.
Evaluation of the morphology and function of cultured human corneal endothelial cells transplanted onto denuded Descemet's membrane of donor corneas.
Corneas from donors (52-80 years old) were obtained from an eye bank. Descemet's membrane was stripped and endothelial cells were removed by mild EDTA treatment. Cells, cultured in the preferred formulation of the culture medium, were identified by RT-PCR of collagen type VIII and keratin-12 and by morphology. Cells (2.5�105) were seeded onto denuded Descemet's membrane from a second donor cornea. The cornea was incubated in culture for up to 1 month. Cell-cell contact of transplanted cells was evaluated by ZO-1 staining. Morphology and ultrastructure were examined by transmission electron microscopy. Pump function was tested by pachymetry after exposure to 200 μM ouabain. Cultured cells were identified as corneal endothelium by characteristic mRNA expression and morphology. The success rate of primary cultures, obtained from corneas stored <5 days after death, was about 99%. Cultures became confluent within one week. ZO-1 staining revealed normal cell shape and cell-cell contacts compared to normal corneas. Furthermore, as can be seen in FIG. 3, after 14 days in organ culture, the cell density (number of cells/mm2) of the transplanted corneas is within the range of both the normal donor and normal recipient corneal cell densities.
With time, cell-substrate adhesion, cell-cell contact, and lateral interdigitation increased, and the cells rearranged to form a monolayer. When the endothelium is functional, it draws water out of the corneal stroma, resulting in a thin cornea. Ouabain, a cardiac glycoside, inhibits the function of the endothelial "ionic pump", causing an increase in corneal thickness. Upon exposure of the transplanted endothelium to ouabain, corneal thickness increased to a level equal to that of corneas denuded of endothelium, as measured by pachymetry. Referring to FIG. 4, pachymetry of transplanted corneas after ouabain treatment is graphically depicted. The open triangles represent thickness measurements from a cornea that was denuded of endothelial cells (negative control). Without a working "pump", this cornea remains thick (about 950 μm). The other symbols represent data from 5 corneas containing transplanted endothelial cells (transplants were maintained for 14 days in organ culture prior to thickness measurements). With exposure to ouabain, corneal thickness increased over a 2-3 hour period and reached the maximum thickness exhibited by the negative control. The ability of ouabain to increase corneal thickness indicates that the endothelium in the transplants was functional prior to ouabain addition.
The various determinations described here show that the morphology and function of transplanted human corneal endothelial cells from older individuals are similar to those of normal endothelial cells. Referring to FIG. 5, thick plastic sections are shown comparing the morphology of normal and transplanted human corneal endothelium. The micorgraph on the left is a section of normal cornea obtained from a 61 year old donor. The micrograph on the right shows a cornea from a 63 year old donor that has been cultured in the growth medium of the invention. The transplanted cornea was photographed after 14 days in organ culture. After this time in culture, a normal monolayer of cells can be seen associated with the recipient Descemet's membrane. The density of the transplanted cells is similar to that of normal endothelium. (Original magnifications: Left micrograph=40�, right micrograph=63�.)
The growth medium of the invention may be applied to a patient's eye as topical drops or injected into the anterior chamber to induce transient proliferation of corneal endothelial cells in older individuals whose visual acuity is impaired due to low endothelial cell counts. Furthermore, cells from an older individual having low corneal endothelial cell density could be cultured in the growth medium of the invention to increase cell numbers. These could then be re-seeded onto the cornea of the patient to increase cell density and improve visual acuity.
The growth medium of the invention may be used as an irrigating solution (most probably not including serum) during anterior chamber surgical procedures to maintain the overall health and stability of the corneal endothelium (which can be compromised during these procedures) and to promote proliferation to replace cells damaged during the procedure. Furthermore, the growth medium of the invention (also without serum) would be a better supportive medium for the storage of donor corneas prior to transplantation than the prior art media.
The growth medium of the invention can support growth of human corneal endothelial cells for use in the development of "artificial" corneas. Up to this time, experimental artificial corneas have been prepared either with endothelial cells from species that grow better, such as mouse, or with SV40 transformed corneal endothelial cells.
With the use of the medium of the invention, researchers can now grow adult human corneal endothelial cells in culture without the need to seed cells onto artificial or cell-derived matrices. This will provide a ready supply of cells for molecular and cell biological studies that have been impossible to perform up to now.
Other Embodiments
The tissue embryonic origin of the corneal endothelium is neural crest. During fetal development, neural crest cells migrate and then differentiate to form many types of tissue. Many of the cell types formed from neural crest do not readily proliferate in vivo. The growth medium of the invention would be useful to induce proliferation in other ocular cells of similar origin, including, but not limited to, lacrimal gland acinar cells, ciliary body epithelium, corneal stromal keratocytes, skeletal muscle of the dorsal iris, and trabecular meshwork epithelium. Other non-ocular cells of similar embryonic origin should also proliferate upon exposure to this medium. Among non-ocular cell types of neural crest origin are sensory neurons, Schwann cells associated with the peripheral nervous system, and smooth muscle cells associated with the branchial arch arteries. Thus, the growth medium of the invention could be useful for repair of damaged tissue made up of the indicated cells, such as peripheral nerve damage and peripheral skeletal muscle damage, or for treating heart muscle after infarction.
The preferred formulation of the growth medium of the invention can be varied by those of skill in the art without compromising the positive effects of the invention as long as the formulation used includes nerve growth factor (NGF).
While the present invention has been described in conjunction with a preferred embodiment, one of ordinary skill, after reading the foregoing specification, will be able to effect various changes, substitutions of equivalents, and other alterations to the compositions and methods set forth herein. It is therefore intended that the protection granted by Letters Patent hereon be limited only by the definitions contained in the appended claims and equivalents thereof.
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US4973493 * | Oct 15, 1987 | Nov 27, 1990 | Bio-Metric Systems, Inc. | Method of improving the biocompatibility of solid surfaces |
US5045454 | Feb 23, 1990 | Sep 3, 1991 | Medi-Cult A/S | Serum-free growth medium and use thereof |
US5332671 | Aug 4, 1989 | Jul 26, 1994 | Genetech, Inc. | Production of vascular endothelial cell growth factor and DNA encoding same |
US5407669 * | Mar 4, 1992 | Apr 18, 1995 | Lindstrom; Richard L. | Method and apparatus of a defined serumfree medical solution |
US5589451 | Sep 21, 1992 | Dec 31, 1996 | Board Of Regents, The University Of Texas System | Methods and treaments for corneal healing with hepatocyte and keratinocyte growth factors |
Reference | ||
1 | * | Kruse et al. Growth Factors Modulate Clonal Growth and Differentiation of Cultured Rabbit Limbal and Corneal Epithelium; Investigative Ophthalmology & Visual Science, 1993, vol. 34, No. 6, pp. 1963-1976. |
Citing Patent | Filing date | Publication date | Applicant | Title |
US6824230 * | Sep 12, 2001 | Nov 30, 2004 | O'sullivan Industries, Inc. | Corner computer workcenter |
US7601487 | Apr 6, 2006 | Oct 13, 2009 | Cleo Cosmetic And Pharmaceutical Co., Llc | Composition using HMW dextran and method for in vitro preservation of corneal tissues |
US20030184194 * | Sep 12, 2001 | Oct 2, 2003 | Richard Probst | Corner computer workcenter |
US20060228693 * | Apr 6, 2006 | Oct 12, 2006 | Soll David B | Composition and method for in vitro preservation of corneal tissues |
CN101597592B | Jun 11, 2009 | Dec 28, 2011 | 山东省眼科研究所 | 人角膜内皮细胞培养液及其制备方法和应用 |
U.S. Classification | 435/405, 435/404, 435/325 |
International Classification | A61K35/12, C12N5/02, A61K38/18, C12N5/071 |
Cooperative Classification | A61K38/185, C12N2500/80, C12N5/0621, C12N2500/84, C12N2500/25, C12N2501/11, C12N2501/115, C12N2501/13, A61K35/12 |
European Classification | C12N5/06B8C, A61K38/18F |
Date | Code | Event | Description |
Sep 14, 2001 | AS | Assignment | Owner name: SCHEPENS EYE RESEARCH INSTITUTE, INC., THE, MASSAC Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:CHEN, KO-HUA;JOYCE, NANCY C.;REEL/FRAME:012260/0222;SIGNING DATES FROM 20010815 TO 20010821 |
Sep 26, 2006 | FPAY | Fee payment | Year of fee payment: 4 |
Jul 10, 2007 | CC | Certificate of correction | |
Nov 8, 2010 | REMI | Maintenance fee reminder mailed | |
Apr 1, 2011 | LAPS | Lapse for failure to pay maintenance fees | |
May 24, 2011 | FP | Expired due to failure to pay maintenance fee | Effective date: 20110401 |


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Characteristics of Excellence in Undergraduate Research (COEUR) Download: http://www.cur.org/publications/publication_listings/COEUR/ COEUR Co-authors Roger Rowlett, Gordon & Dorothy Kline Professor of Chemistry, Colgate College Linda Blockus, Director of Undergraduate Research, University of Missouri Susan Larson, Professor of Psychology, Director of Undergraduate Research, Concordia College
Outline of session A bit about CUR and undergraduate research Purpose and motivation for COEUR Overview of COEUR Executive summary of the major topics addressed in COEUR Uses for COEUR Opportunity for discussion and conversation
Council on Undergraduate Research (www.cur.org) Founded in 1978, is a national organization of individual and institutional members representing more than 900 colleges and universities. Mission of CUR: To support and promote high- quality undergraduate student-faculty collaborative research and scholarship.
CUR activities Biennial conference & specialized institutes for faculty and administrators, including Undergraduate Research Program Directors CUR Dialogues (brings faculty/admin. to DC to interact with funders) Publications and quarterly journal Advocacy with funding agencies & government Consulting and Program Review Now responsible for student-centered annual NCUR meeting
Defining Undergraduate Research CUR Definition: An inquiry or investigation conducted by an undergraduate student that makes an original intellectual or creative contribution to the discipline.
Benefits of undergraduate research Enhances student learning through mentoring relationships with faculty Increases retention Increases enrollment in graduate education and provides effective career preparation Develops critical thinking, creativity, problem solving and intellectual independence Develops an understanding of research methodology Promotes an innovation-oriented culture http://www.cur.org/about_cur/fact_sheet/
AAC&U 2013: THE QUALITY OF U.S. DEGREES: Innovations, Efficiencies, and DisruptionsTo What Ends? Explore a wide range of approaches to quality learning Address important efforts to increase completion rates and access to higher education, alongside comprehensive efforts to ensure the integrity of college degrees Make sure that all degrees offer students pathways along which they will creatively engage complex, real-world challenges Ensure that these experiences produce assessable evidence of authentic student work and achievement http://www.aacu.org/meetings/annualmeeting/AM13/index.cfm
What is COEUR? COEUR is a summary of best practices that support and sustain highly effective undergraduate research environments The purpose of COEUR is to provide a guide for those who wish to build, evaluate, and maintain robust, productive, meaningful and sustainable undergraduate research programs COEUR is for institutions, programs, academic departments, faculty and administrators as they work to develop and enhance their undergraduate research programs
Campus mission and culture A campus culture that values and rewards undergraduate research (UR) is essential. Institutional commitment to UR Scholarly faculty and faculty commitment to UR Broad disciplinary participation by students Accessible opportunities Integration with other engaging & high impact opportunities
Administrative support Administrative support and commitment are critical for excellent UR programs. Intramural budgetary support and, if appropriate, startup funding Faculty load credit for supervising undergraduate research and for research- related tasks Student support, including for travel Research grants office
Administrative support: Office of Undergraduate Research Most successful UR programs have a central office, which oversees campus-wide UR activities Director of Undergraduate Research Full- or part-time Sufficient, well-located space Infrastructure support, such as support staff, an office and publicity budget
Research infrastructure To sustain productive research and scholarship with undergraduates, research infrastructure is needed. Space, instrumentation and equipment Library and computational resources Research oversight structures Support, administrative and technical staff
Professional development opportunities Professional development should be available for all those involved in UR. Research leaves Mentor training for faculty, graduate students and post-doctoral fellows Other professional development opportunities, for all involved in UR
Recognition An institution that values UR as an activity integral to its mission will provide clear, tangible forms of recognition for faculty and students. Acknowledgement of undergraduate research in promotion and tenure guidelines, salary review and campus awards Prominent publicity for research accomplishments
External funding External funding is essential for the development of a rich, productive, and contemporaneous faculty-student research environment. Faculty should seek and be supported for seeking external research funding Institutional research funding should also be available
Dissemination of Research Faculty and students should strive for peer- reviewed dissemination in the form of publications, exhibition or performances. Other desirable forms of dissemination include Presentation at professional meetings Student research conferences On-campus symposia
Student-centered issues UR experiences should incorporate best practices in undergraduate education and UR programs should strive to integrate student research with other engaging experiences, such as Capstone and Writing experiences Study Abroad, Global Learning Service Learning, Citizenship Leadership, Student Development Orientation and First Year Experiences Peer Communities and Peer Learning
Student-centered issues Other student-centered issues Creating a community scholars, possibly with peer mentoring/teamwork Programming to promote professional development Providing opportunities for early and sustained involvement in UR Establishing and communicating expectations Providing developmentally appropriate expectations Faculty mentor availability
Curriculum Departments and programs should design curricula that expose students to skills necessary to undertake UR and curricula should be designed in ways to facilitate faculty and student involvement in UR. Research-supportive curriculum Integration of teaching and research Attention to faculty load management Training opportunities and workshops E.g., Responsible Conduct of Research Student course credit for research
Summer research program A robust summer research program is essential to a vibrant UR environment, and includes Faculty and student compensation Student access to facilities and student services, including housing Programming, including research symposia Coordination between multiple programs and attention to issues for hosting students
Assessment activities Institutions and programs should have multiple approaches to assessment to recognize successes, illuminate gaps, and collect benchmarking data. Assessment of student learning outcomes Program assessment and evaluation Collection of participation/outcome data
Assessment activities Program assessment and evaluation should include Feedback from faculty and students on their satisfaction with activities Sustainable method to collect data on participants (e.g., demographic information) and faculty mentors (e.g., outcomes) Mechanism to track external funding and post- graduate career plans of students
Strategic planning Institutions that aspire to creating and sustaining an excellent undergraduate research environment will have thoughtful and clearly articulated benchmarks and strategic plans.
Excellence in UR These 12 characteristics (and their many sub- characteristics ) work together to create excellent UR programs "...a successful undergraduate research program must be embedded in the culture of an institution and thereby supported through multiple organizational structures, policies, and programs. By using COEUR to guide efforts aimed at achieving this goal, an institution is much more likely to achieve this desired result. Andrea Chapdelaine, Provost and Vice President for Academic Affairs, Albright College
Faculty support Adequate startup funding Professional development leave opportunities and travel support Research grants office Recognition of undergraduate research in promotion & tenure guidelines Creating time for faculty
Faculty load credit for supervising undergraduate research Research-supportive curriculum & scheduling Integration of teaching & research Technical support staff Reassigned time for research related-tasks Undergraduate Research Office/Coordinator
Undergraduate research office Full or part-time coordinator Interfaces with other campus constituents Promotes UR to internal and external audiences Oversees assessment activities Distributes research funding to students Coordinates campus-wide research symposium Can seek grants, implement strategic planning around UR
Summer research program Research-supportive teaching calendar Student and/or faculty compensation Affordable student housing/services Student programming Student peer community Summer research symposia Faculty mentoring as professional development
Discussion Will use this a time to learn how others are moving towards excellence in UR The successes you have had at your institution in achieving these characteristics The challenges you have had What are some things characteristics of excellence COEUR that particularly resonate with you/your campus?
Uses of COEUR Purpose of COEUR To provide a guide for those who wish to build, evaluate, and maintain robust, productive, meaningful and sustainable undergraduate research environments Serve as a guide to sustain best practices in undergraduate research Many examples of uses of COEUR in the CUR publication
Function as a guide for strategic planning Provide programmatic and institutional benchmarking against national standards CUR in process of developing a system for institutional reviews making use of COEUR Uses of COEUR
Outline a structure for UR self-study Utilized in assessment and evaluation of UR Provide guidance for resource allocation decisions Encourage the development of new initiatives related to UR Provide a framework for campus discussion and setting priorities Uses of COEUR
Examples of how COEUR is being used General discussion about the document to improve the undergraduate research experience Used for integrating undergraduate research in the curriculum Used to address faculty professional development needs Used to develop a mission statement or strategic plan around undergraduate research Used for improving faculty research productivity/support Used in conversations within departments about workload, evaluation and rewards
Discussion and Questions How can you use the COEUR document/ framework to improve UR on your campus? How can it be used at different levels in your institution (e.g., by deans or other administrators, faculty, communications, marketing, advancement)?
COEUR on-line Download or purchase a hardcopy, find executive summary here, too: http://www.cur.org/publications/publication_listings/ COEUR/
CUR at AAC&U CUR Session - Developing a Shared Vision to Expand, Sustain, and Connect Undergraduate Research Culture and Practice. Friday @ 4:15pm, Grand Hall East C CUR Reception – Friday (5:30-7:00 pm) in the Hanover C Room
Upcoming Webinar Faculty Support and Undergraduate Research: Innovation in Faculty Role Definition, Workload, and Reward Please join Nancy Hensel and Elizabeth Paul as they discuss the issues covered in their new publication When: Wednesday, February 6th 2-3pm et Register here: http://www.cvent.com/d/ycq44r/4W Pricing: Enhanced – Complimentary (free to first 50, $20 after) Institutional Members -- $30 Individual Members -- $50 Non-Members -- $75
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Please note: NFPA 87 moved from the Annual 2018 to the Annual 2017 revision cycle. Beginning with the Fall 2016 NFPA Standards, all Public Inputs and Public Comments must be submitted online. This is yet another enhancement that allows NFPA to facilitate wider and easier participation in the development of its Standards. Read more on how to submit public input and public comment
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TOWN OF ULSTER — A Kingston man was arrested Thursday evening and charged with driving drunk with his 15-year-old daughter in the vehicle, said state police.
Police said William Harder, 53, was driving east on Frank Sottile Boulevard when he turned left into the path of a Nissan Altima being driven by an 18-year-old Kingston woman. Her car then struck a van waiting to enter Frank Sottile Boulevard.
The driver and a passenger in the Altima were treated for minor injuries. Harder was charged with felony drunk driving under Leandra's Law and released to a relative.
The Ulster Hose Fire Department and Town of Ulster Police assisted at the scene.
Nathan Brown
Kingston man charged with felony DWI after crash
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StemCor Signs Agreement With Hospira to Market New Medical Device to Oncologists and Hematologists
(Logo: http://www.newscom.com/cgi-bin/prnh/20071030/STEMCORSYSTEMSLOGO)
StemCor will develop the System for Hospira, and Hospira will manage theclinical trial program, leading to commercialization. The System has 510(k)clearance from the U.S. Food and Drug Administration and CE Mark in Europe,and Hospira plans to initiate post-approval clinical use studies in early 2009to support product launch thereafter. Under the agreement, Hospira will marketthe device to Oncologists, Hematologists and other physicians specializing inbone marrow transplantation.
"We are excited to develop this System's potential in collaboration withHospira, a leading global specialty pharmaceutical and medication deliverycompany," said Vartan Ghazarossian, Ph.D., President and CEO of StemCor. "Thisis a specialized market that varies from country to country, and we arepleased to have a strong distribution partner in both the U.S. and around theworld."
Andrew Robbins, Director of Strategy and Ventures at Hospira, said, "Thisagreement is a step forward as Hospira seeks to provide innovative productsfor the oncology market. Hospira is excited to provide a new device tofacilitate bone marrow harvest, with the goal of improving the donorexperience."
About StemCor's Product
StemCor's proprietary System is designed to rapidly and easily harvestbone marrow in a minimally invasive manner, in the outpatient setting, andwithout general anesthesia. The System consists of an access guide, a poweredhandle that drives a flexible atraumatic shaft through which marrow isaspirated, and an integrated marrow collection container. The shaft gainsaccess to the bone marrow cavity through the access guide to allow the removalof bone marrow through a single entry site. This is in contrast to the currentpractice of bone marrow aspiration through the repeated insertion of a needleinto multiple sites in the iliac crest of the hip, which usually requiresgeneral anesthesia, an operating room, and multiple clinical personnel.Preclinical studies demonstrated the ability of the System to safely harvestlarge volumes of marrow with greater stem cell activity than is contained instandard needle aspirates.
About StemCor Systems
StemCor Systems is a privately held medical device company located in theSan Francisco Bay Area. The company's initial product is a proprietary,minimally-invasive bone marrow collection system. The technology was licensedexclusively from Stanford University.
About Hospira
Hospira, Inc. is a global specialty pharmaceutical and medication deliverycompany dedicated to Advancing Wellness(TM). As the world leader in specialtygeneric injectable pharmaceuticals, Hospira offers one of the broadestportfolios of generic acute-care and oncology injectables, as well asintegrated infusion therapy and medication management solutions. Through itsproducts, Hospira helps improve the safety, cost and productivity of patientcare. The company is headquarted in Lake Forest, Ill., and has more than14,000 employees. Learn more at http://www.hospira.com.Contact: Vartan Ghazarossian, Ph.D. President and CEO StemCor Systems, Inc. 650-321-6884 email@example.com
SOURCE StemCor Systems, Inc.
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text: 298 FXUS63 KSGF 271210 AFDSGF Area Forecast Discussion National Weather Service Springfield MO 710 AM CDT Mon Mar 27 2017 .SHORT TERM...(Today and tonight) Issued at 243 AM CDT Mon Mar 27 2017 Upper level system currently situated over eastern Kansas with the surface low over central Oklahoma and an associated warm front situated across northern Arkansas. Showers with some embedded thunderstorms continue across the area. As the upper level system makes its was into the Ohio Valley...the surface front will continue to lift northward during the day. The moist unstable air to the south of this front could make it into south central Missouri by this afternoon. If this pans out...there will be a marginal threat for severe storms with hail and wind being the primary threat. Highs in the warm sector will make it into the upper 60s to possibly 70 this afternoon while areas in west central MO will be in the upper 50s. .LONG TERM...(Tuesday through Sunday) Issued at 243 AM CDT Mon Mar 27 2017 Progressive pattern will continue through the forecast period with two systems expected to affect the area during the period. The first system is currently approaching the California coast and will dig into the southern Rockies and form a closed low in the four corners area Tuesday afternoon as it makes its way into the southern Plains on Wednesday. Rain should begin late Tuesday night with SPC having the area in a slight risk for severe during the day on Wednesday. This system also has the potential for dropping 1-2 inches of rain area wide before departing on Friday. Friday and Saturday should be mild with temperatures near to slightly above seasonal normals. The next system then approaches Saturday afternoon and remains through the weekend. Still some issues with timing and positioning between the different models that will need to be resolved in later runs. Overall...temperatures will warm into the mid to upper 60s for highs and low to mid 50s for lows with the approach of each system and fall into the mid to upper 50s for highs and low to mid 40s for lows as the system passes. && .AVIATION...(For the 12Z TAFS through 12Z Tuesday morning) Issued at 703 AM CDT Mon Mar 27 2017 A warm front in the vicinity of the Ozarks this morning will slowly lift north today. This will bring continued showers and scattered storms. Ceilings and visibilities will initially be VFR with ceilings falling to MVFR to IFR late this morning into this afternoon. Overnight ceilings and visibilities at area terminals will impact aviation concerns as ceilings fall to IFR with MVFR visibilities. && .SGF WATCHES/WARNINGS/ADVISORIES... MO...NONE. KS...NONE. && $$ SHORT TERM...Gaede LONG TERM...Gaede AVIATION...Hatch


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johnmperry commented on the word prince albert
Wikipedia: "The Prince Albert piercing (PA) is one of the common forms of male genital piercing. The PA pierces the penis from the outside of the frenulum and into the urethra."
So now we know!
Different from ordinary albert.
June 18, 2008


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Another theme that I'm not familiar enough with. I started watching Blade Runner the other year, but couldn't get into it. I need to give it another try cause drawing this was a blast! I probably spent more time on it than I needed to, but I was having too much fun playing with ink.
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with Chris Hedges
LeighaCohen on Aug 9, 2014
[…] Prior to the rally starting, I was approached by Chris Hedges who mentioned that he had written an 8 minute speech that he wanted to deliver to the thousands of people attending the rally. However, he was told that all of the speakers where being limited to 2 minutes speaking time at the rally.
This is that special speech that Chris Hedges wanted to deliver that day that talked about the historical and religious background to what is the re-occurring violence in the area that the Israelis and Palestinians presently live in. […]
[embedding disabled, please watch on Youtube, or see below.]
Updated: Sept. 8, 2014
Transcript of Hedges' speech
Biggest ever UK demonstration for Gaza
Stop the War Coalition on Aug 9, 2014
150,000 take to London's streets on 9 August 2014 to protest against four weeks of Israeli barbarism that killed 2000 Palestinians, including over 430 children. And we were there to say to the people of Gaza facing such horrific crimes against humanity: You are not alone. http://stopwar.org.uk/
#GazaDayofRage: Tens of thousands march worldwide in support of Palestinians
RT America on Aug 8, 2014
People across the globe have gathered to support the plight of Gaza, with the most impressive turnout taking place in London. Since the start of the Israel-Hamas conflict a month ago, over 1,800 Palestinians, mostly civilians, have been killed. READ MORE: http://on.rt.com/329tul
Updated: Sept. 8, 2014
Cornel West: "We won't stand for annihilation" in Palestine
News2Share on Aug 2, 2014
For more, go to News2share.com! Subscribe above to get all of our coverage on the Palestine/Israel conflict!
Democratic Socialist philosopher Cornell West speaks at the pro-Palestinian march on Washington, where he juxtaposes issues facing Palestinians to issues facing African Americans in The United States today.
Filmed by Ford Fischer (@fordfischer on twitter)
Updated: Aug. 10, 2014
(2014) Cornel West: Speaking at Gaza Rally in NYC
via Youtube
see also
Exclusive: Israel's Video Justifying Destruction of Gaza Hospital Was From 2009 by Gareth Porter
Hamas Rocket Launches Don't Explain Israel's Gaza Destruction by Gareth Porter, Sept. 9, 2014
Chris Hedges Supports BDS + Aftermath of Assault on Gaza Worse Than Operation Cast Lead
Noam Chomsky: Hideous. Sadistic. Vicious. Murderous. + Transcript
Noam Chomsky: Israel Committing Major War Crimes In Gaza
Alison Weir: The Hidden History of How the U.S. Was Used to Create Israel (must-see)
A War Crime In Progress by Jason Farbma