text:
Phase 2 Study to Explore the Efficacy of Novel Proteasome Inhibitor in
Patients with Relapsed and Refractory Multiple Myeloma
SOUTH SAN FRANCISCO, Calif. and NORWALK, Conn., Aug. 15 /PRNewswire/ -- The Multiple Myeloma Research Consortium (MMRC) and Proteolix, Inc. today announced the enrollment of the first patient in a multi-center Phase 2 clinical trial to study Proteolix's potent and selective proteasome inhibitor, carfilzomib (PR-171), in patients with relapsed and refractory multiple myeloma. Ten MMRC Member Institutions will participate in the study, under the MMRC leadership of Melissa Alsina, MD, H. Lee Moffitt Cancer Center & Research Institute. The nine additional sites are the City of Hope, Emory University, Cancer Center at Hackensack University Medical Center, Mayo Clinic, Princess Margaret/University Health Network, Saint Vincent's Comprehensive Cancer Center, University of Michigan, and Washington University.
The MMRC is the only research model of its kind that brings together 13 leading academic institutions to accelerate the development of novel and combination treatments for multiple myeloma, an incurable cancer of the plasma cell.
"Proteasome inhibitors are an important class of drugs for the treatment of multiple myeloma and we are proud to work with Proteolix to advance the clinical development of carfilzomib," said Kathy Giusti, Founder and Chief Executive Officer of the MMRC. "This trial and the others the MMRC are facilitating underscore our commitment to bring better, more effective treatments to myeloma patients as quickly as possible."
The trial will evaluate the overall response rate (ORR) for two cycles of carfilzomib in patients with multiple myeloma who have previously received specific FDA-approved therapies, have relapsed after two or more of such therapies, and are refractory to the most recently received therapy. Secondary objectives of this study include safety and tolerability, clinical benefit response (CBR), time to progression (TTP), duration of response (DOR), progression-free survival, and best ORR throughout the study. Patients enrolled in the trial will receive carfilzomib twice weekly for three weeks every 28 days.
"Based on promising laboratory and clinical data, we believe that carfilzomib holds promise in treating patients with multiple myeloma, including those for whom other treatments have failed," said Sundar Jagannath, M.D., Saint Vincent's Comprehensive Cancer Center, where the first patient was enrolled. "We are excited to bring this compound into the MMRC as a critical step in bringing this new treatment to patients."
In the coming weeks, the MMRC and Proteolix will also begin enrolling an open-label, single-arm, Phase 2 study of carfilzomib in patients with relapsed multiple myeloma, who will be stratified by bortezomib (Velcade(R), Millennium Pharmaceuticals, Inc.) history.
About Carfilzomib
Carfilzomib is a structurally- and mechanistically-novel proteasome inhibitor that exhibits a high level of selectivity for the unique N-terminal threonine active sites within the proteasome. Carfilzomib is similar to bortezomib in that it is a potent inhibitor of the proteasome chymotrypsin- like activity, but unlike bortezomib, carfilzomib has shown minimal cross- reactivity with the other catalytic sites within the proteasome or across other protease classes. Phase 1 clinical studies confirmed that patients who have relapsed or progressed following multiple therapies can still achieve durable anti-tumor responses with carfilzomib. In addition to the two Phase 2 single-agent trials in myeloma and ongoing studies in lymphoma, a clinical trial in solid tumors and a trial exploring carfilzomib in combination with an FDA-approved agent will be initiated by the end of the year.
"The Phase 1 data consistently demonstrate carfilzomib anti-tumor activity in myeloma patients who have failed multiple lines of therapy, and we are excited to be moving our clinical program forward. We are very pleased that the MMRC sponsorship has made the rapid initiation of our Phase 2 trials possible and has enabled us to reach out to a larger group of myeloma patients. The thoughtful scientific expertise and collaborative effort of this group have helped speed development of new agents in the field of multiple myeloma," said Lori A. Kunkel, M.D., Chief Medical Officer of Proteolix, Inc.
About the Multiple Myeloma Research Consortium (MMRC)
The Multiple Myeloma Research Consortium (MMRC) is a 509(a)3 non-profit organization that integrates leading academic institutions to accelerate drug development in multiple myeloma. It is led from MMRC offices in Norwalk, Conn., and comprises 13 Member Institutions: City of Hope, Dana-Farber Cancer Institute, Emory University's Winship Cancer Institute, the Cancer Center at Hackensack University Medical Center, H. Lee Moffitt Cancer Center & Research Institute, Mayo Clinic, Ohio State University, Roswell Park Cancer Institute, Saint Vincent's Comprehensive Cancer Center of Saint Vincent Catholic Medical Centers of New York, University Health Network (Princess Margaret Hospital), University of Chicago, University of Michigan, and Washington University. In addition to these trials with Proteolix, the MMRC is supporting six other clinical trials exploring several investigative agents.
The MMRC was founded in 2004 by Kathy Giusti, a myeloma patient, and with the help of the scientific community. The MMRC is a sister organization to the Multiple Myeloma Research Foundation (MMRF), the world's leading funder of multiple myeloma research. The MMRC is widely recognized as an optimal research model to rapidly address critical challenges in drug development and to explore opportunities in the today's most promising research areas- genomics, compound validation, and clinical trials. The MMRC is the only consortium to join academic institutions through membership agreements, customized IT systems, and an integrated tissue bank. For more information, please visit http://www.themmrc.org.
About Proteolix
Proteolix, Inc. is a biopharmaceutical company dedicated to discovering, developing and marketing pharmaceutical products that target certain cancers and immunological conditions by inhibiting the proteasome and thereby disrupting protein turnover in cells. In addition to its lead product candidate, carfilzomib (PR-171), which is delivered intravenously and is currently in multiple clinical trials to evaluate its safety and efficacy in different types of cancer, Proteolix is developing next generation proteasome inhibitors, including an oral proteasome inhibitor and a selective immunoproteasome inhibitor, to expand the therapeutic potential of this new target class. Proteolix is headquartered in South San Francisco. For more information, please visit the Company's website at http://www.proteolix.com.
MMRC Contact: Anne Quinn Young, Program Director, 203-652-0212
Proteolix Contact: Stephen R. Brady, Executive Director of Business & Legal Affairs, 650-615-7521
|SOURCE Proteolix
Copyright©2007 PR Newswire.


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Joined: 04 May 2005
Posts: 6266
Location: Knoxville, TN, USA
Posted: Sun 02 Nov 2008, 23:27
Post subject:
Putting Unleashed under a Revisioning System
Subject description: Thoughts?
This has been discussed a little in different spots, but it was always an off topic side discussion. I'm very serious about setting something like this up, so I'm starting a real thread for it.
Reasoning for putting Unleashed in a revisioning system like Subversion:
It allows the developers to contribute directly.
Direct contribution may make certain things easier, such as going through and properly localizing Puppy, and keeping it that way. (Obviously we'd have to watch the devs and yell at them when they don't localize their code).
Removing the middle man removes opportunity for accidental errors.
Removing the middle man lifts a lot of burden from the "coordinator", assuming we keep using coordinators. He doesn't have to manually add in every little change. If we stick with the coordinator approach, he would still make the decisions and stuff, just not have to implement everything himself. I'm sure WhoDo understands what I'm saying here
Changes are recorded automatically. If you notice that something has broken in the latest release of Puppy, you can look up exactly what has changed in each file.
By allowing anonymous reading, people can see what has changed on a day to day basis, and who changed it. They can test new features immediately, or simply satisfy their curiosity. If a bug fix is implemented, it is available immediately.
Collisions are much less likely. A collision is when two people are working on the same file, and one submits their modified one after the other has already submitted his, causing the other one to be overwritten. It is difficult to keep track of that sort of thing when middle-men are involved. SVN will automatically notify you if the file has changed while you worked on it, and it will help you to merge the changes together, often taking care of it automatically (like if you were working on the bottom of the file, and the other person modified the top).
This link explains some of what I was talking about with regard to collisions, and helps explain how SVN works:
There are several options for what software to use. I'm leaning toward SVN, because that seems the most straightforward. Git has some fancy features, but we don't really need them AFAIK.
So, I've been working on setting up my old computer to serve as a test server while we figure out the best layout and stuff. Then, Caneri is considering hosting us on one of his new servers if they prove to be stable.
I was going to get it all set up tonight and then start this thread for discussion, but I ran into a snag: Neither SVN nor Git can handle device files (like in /dev/). We could get around that by keeping those in an archive, and having a script to unarchive them and remove the archive before building Puppy. We probably need a script to go from the svn layout to a proper unleashed layout anyways, so that could just be part of it. There could be another one to go in reverse. I'm going to play with this next time I have free time.
Does anybody have a better idea? Or know of another software that handles these files?
How best to handle upgrades to new base-versions of Puppy (such as after a rebuild from t2)? I think that the simplest method would be to single out any packages with significant Puppy changes (like 0rootfs_skeleton) and handle them by doing an svn copy on the old version to the new version's name, then replace the files with the new version. That way the histories for the files that are kept (like the wizards) would be preserved. Things with almost no Puppy changes might be easier to just import, I dunno. I still haven't gotten around to fiddling with T2, as I've been so busy with school. What are your thoughts?
Unleashed is big. We will need to set up a method to download the actual packages and such for unleashed from the package server like we do now, and then extract them and move them into the proper layout for SVN. Then do the svn checkout over those files, using the --force option. Then we'd have to do an 'svn revert' to bring it up to date with the server (when it checked out the files, it considered any differences in the local files to be new, not old, so we'd need to use revert rather than update). Finally, we may need to run a script to get a list of all files under revision control, and then go through the tree and remove any that aren't. Otherwise if a file that existed when the package was made gets removed later, it will still hang around because SVN will ignore it. This doesn't cause any problems directly, but it could be confusing to the user, as he may not realize that the file isn't being used, or may think that the file belongs and re-add it, causing issues. All this stuff can be scripted of course, so that the user just has to run the script and it will take care of everything.
Maybe doing all that isn't necessary, but I think it might be more efficient than just checking out the entire system. I think a checkout would download a lot more small files, rather than the smaller number of package files. It depends on how SVN transfers its data I suppose. Anybody know which would be more efficient?
What file layout would be best? I suspect that it would be easiest to have the standard 'tags', 'branches', and 'trunk' directories at the top, then put the main line in 'trunk'. This way when doing a major upgrade of Puppy, it can be done in /branches, and when a release version is ready, the whole thing can be put into /tags with one command. This makes it seem like maybe branching a single package wouldn't work well, but SVN is very flexible. You can simply branch it to /branches/my_branched_package. SVN doesn't actually care if the layout of everything in /branches matches /trunk. When you finish, just remove it from /branches. Tagging packages would be more of an issue, but wouldn't really be necessary afaik. If the package reaches a good stable stopping point before the next version of Puppy is ready, just copy the package over to a new version number and keep going, leaving the packages.txt file pointed at the old stable version until the new one becomes stable. Every now and then we could prune out the old unused versions, just to make things cleaner. The wouldn't actually be removed though, since it's SVN, so if you need the old version you can just go back and get it.
I also think that the packages directory should be split out from the unleashed_core. For people who maintain a full local tree, it makes no real difference. But for people who just want to check out the unleashed_core so they can work on it don't want to have to do fancy commands to skip checking out all of the packages. So separating it into a packages directory containing all the packages and an unleashed_core directory for the core would correct this. They can be put back together easily when it's time for a build, or simply simlinked.
So the overall structure I'm envisioning would be like this:
bash-3.00# tree
|-- branches
|-- tags
`-- trunk
|-- packages
| |-- 0rootfs_skeleton-4.02
| |-- pkitchensink-9.54
| `-- some_prog-0.24
`-- unleashed_core
|-- boot
|-- isolinux-builds
|-- kernel
`-- packages -> ../packages
(obviously many files and directories have been omitted for clarity)
Any other thoughts? Problems? Better ideas?
How will something this large handle? That question is the main reason I'm setting up my test server. I want to experiment with it to see what kind of performance I get. I also want to simulate a large number of changes and see how fast the size grows. It's running on a 450MHz PIII, so it isn't the fastest machine in the world, but it's reasonable. If it performs well on this, it ought to be just find on Caneri's server, CPU wise.
Initial numbers: it looks like when you take a 996 MB unleashed tree and import it into SVN (minus the device files, which are probably insignificant), it only seems to use 269 MB. So it looks like it compresses stuff. That's good. I was expecting it to be 10% more than the original, but it's actually 75% less than the original.
Is using the svnserve program good enough (for now)? Does anybody think we really need to be using encryption to contribute? Does anybody think that they in particular will need an encrypted connection (oppressive laws or whatnot)? I do plan to work out a web frontend, but that's low on my priority list.
I have the test server running and most of the data loaded in. I need to get a little more done before I can make it public though, and I won't have time tonight. I have to go decide what classes to take next semester, which is harder than it sounds - have to make sure the schedules work out properly. Pain in the butt. Then if I don't get in and sign up immediately, a key class may be filled up and have broken the entire schedule. I think I'm in the very first group to sign up this year though, so hopefully that won't be an issue.
How many people are interested in playing with the test server? If you tell me now I can get you all usernames right away. Or should I just make a generic test user and post the password here? It is only a test server, so that's an option for now. Unless people start abusing my bandwidth. I'm on my campus's network, and the policy here is that hitting a GB a day more often than once a week or so is abusive.
Hopefully I'll be able to finish up on Tuesday. Nearly there now, but I'll probably spend all evening tomorrow doing homework.
So, discuss! Any deal-breaking problems I've overlooked? Any better options? Any suggestions? Speak boy, speak.
Good doggy
Oh, and to head off the "SVN has been tried before, didn't work" argument: No, it has not. Not like this, anyways. An SVN for Puppy-related programs is one thing. An SVN for the official Unleashed tree is quite another. Until now, Barry has done most of the work, and he did it himself. Now the Community is supposed to do the work. What better way than to simply allow the Community to do the work? As opposed to picking one person to shoulder the burden and try to put together everything that everybody is submitting to him? No. Let the devs develop, I say.
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Joined: 28 Jan 2007
Posts: 1169
Location: USA
Posted: Mon 03 Nov 2008, 01:41
Post subject:
is there some reason you are setting up a private svn? some inadequacy on sourceforges part?
there is the concern that the svn server could fail.... witch is an issue with private svn moreso than source forge
if you are worried about the size... i don't think even 500mb is an issue there are larger project on source forge... also unleashed isn't that big is it? the kernel should not be in svn... should it? or any binary package
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Joined: 11 Jul 2006
Posts: 4440
Location: Lake Macquarie NSW Australia
Posted: Mon 03 Nov 2008, 03:17
Post subject: Re: Putting Unleashed under a Revisioning System
Subject description: Thoughts?
Pizzasgood wrote:
[*]Removing the middle man lifts a lot of burden from the "coordinator", assuming we keep using coordinators. He doesn't have to manually add in every little change. If we stick with the coordinator approach, he would still make the decisions and stuff, just not have to implement everything himself. I'm sure WhoDo understands what I'm saying here
WhoDo "understands", applauds, begs and pants in anticipation!
cb88 wrote:
if you are worried about the size... i don't think even 500mb is an issue there are larger project on source forge... also unleashed isn't that big is it?
Oh yes it is, cb88. In fact it is significantly bigger than that. Unleashed core for 4.1.1 is 51Mb but there is around 590Mb+ of packages in the basic Unleashed tree, and up to 1Gb for a comprehensive tree - maybe more if we have a significant boost in private development for Puppy. Keeping those up-to-date is a major task for any Puppy builder, and is one of the reasons why I stipulated that I wouldn't be spending time chasing package updates and bugs in 4.2 without some assistance from the community. PG's idea puts that in a framework that package developers don't have to PM/email the coordinator with every request to include a new or updated package in the tree.
It doesn't matter to me whether the repository exists on Sourceforge or some other private/public server. All that matters is that at any point in time I can capture a snapshot of the Unleashed tree to build a release, and I'm reasonably sure that the most up-to-date packages are in that snapshot. At the moment that involves package devs sending me updates via email or PM, or them uploading and me downloading updates from a shared FTP server to my Unleashed partition. The problems come when I'm not sure whether what is in that partition is the latest I've been provided or the latest available.
I'm not semi-retired like BarryK, and I have to make time for Puppy alongside my real job and my family life. Anything that makes it easier for me to contribute my bit to Puppy is a plus in my book. I'm too old and too set in my ways to risk a divorce for my hobby!
Actions speak louder than words ... and they usually work when words don't!
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Joined: 26 May 2006
Posts: 2946
Location: Southampton, UK
Posted: Mon 03 Nov 2008, 07:49
Post subject:
cb88 wrote:
is there some reason you are setting up a private svn? some inadequacy on sourceforges part?
My understanding was that sourceforge is unwilling to host entire distros on svn.
I would be interested in having at least read access for automated testing. I don't make changes that often so would be happy to submit changes to someone else if I didn't have write access.
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Joined: 25 May 2005
Posts: 4839
Location: Manila
Posted: Mon 03 Nov 2008, 19:34
Post subject: core
Thanks, Pizzasgood.
A number of terms here refer to a filesystem and/or minimum size for Puppy, like "base version", "unleashed core", or "0rootfs_skeleton". We have user-oriented terms, too, like "onebone" (no X) and "barebone" (no big applications). These terms are relevant to the SVN with respect to limiting its scope for building a working base.
Someone (or a small group) will have to decide what constitutes a minimal Puppy build, from which larger builds can be based on. The build script itself may have to be changed. An illustrative question could be, "What if someone wanted to build a Puppy with a different GTK version, or would not use GTK?", or "Would 'building Puppy' be synonymous to 'using GTK', and if so, how would different GTK versions be handled?"
New PCs/netbooks require new drivers, and new kernels include new drivers and features. This adds complications to a build system. Forum member amigo describes one way out, which is to use a longtime supported kernel, like 2.6.16 c/o Adrian Bunk (which is now
). (This is one of the questions in coming up with a basic build of Puppy.)
Puppy user since Oct 2004. Want FreeOffice?
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Joined: 04 May 2005
Posts: 6266
Location: Knoxville, TN, USA
Posted: Mon 03 Nov 2008, 23:14
Post subject:
is there some reason you are setting up a private svn? some inadequacy on sourceforges part?
I'm not sure if inadequacy is the right word, but yeah. I read their terms, and they basically don't like to host entire distros, though they will consider it if asked. But the main thing is their name - sourceforge. They are mainly a source place. I'm not talking about sources, I'm talking about the entire unleashed tree. This is the intermediate stage between compiling the binaries from the source files, and the iso itself. It's where everything is put together.
I'm not trying to make the SF account obsolete. Actually, I think the two repositories would cooperate. SF is where the development of applications for Puppy could happen. For example, I'm using it for my RetroVol program. If we decide to include that in Puppy someday, a binary unleashed package could be put together and imported into the Unleashed SVN.
WhoDo mentioned that he doesn't particularly care where this is set up. I agree. I don't think it would fly very well with SF though, and Caneri has offered to host us if those new servers work out. That would give the Puppy community much more control over the server than if we were hosted elsewhere. If it doesn't work out with Caneri, then it may be worth contacting SF and seeing if they'd make an exception for us. I think Google also hosts some open source projects? Maybe they'd be another place to inquire. Right now though, I'm more concerned with getting a test server working so we can figure out what we'll need. Then if we do have to look elsewhere, we'll at least have a pretty good idea of what to ask for.
1: I was going to get it all set up tonight and then start this thread for discussion, but I ran into a snag: Neither SVN nor Git can handle device files (like in /dev/). We could get around that by keeping those in an archive, and having a script to unarchive them and remove the archive before building Puppy.
And, a good way to do this is to go into each package with device files (mainly 0rootfs_skel) and place them into a tar archive for that package, and then add some lines in that package's pinstall.sh script to extract them and remove the archive. Besides being a nice clean way to do it, it also means that in
the SVN and Unleashed tree's normal state, the device files would be in the archive. I think that's probably a good thing, because I've had some issues with device files becoming messed up when I moved them around too much. I think it was transferring them to my laptop via scp. This way they stay archived, so things can be moved around safely. It may be a slight annoyance to have to add new device files to the archive, but it's pretty rare that they ever need to be dealt with, so not a real issue.
I would be interested in having at least read access for automated testing.
My thinking has always been to have anonymous read access. Maybe find a way to disable checking out the entire thing at once anonymously, IF bandwidth becomes a problem, but anybody should be able to check out any revision of any package any time, IMHO.
@raffy: I do agree that there is a lot we can do to improve the puppy creation process, especially with regard to further facilitating puppy derivatives. But I think that's a topic that is outside the scope of what I'm trying to do here. For example, I think that we should maintain at least one extra packages.txt file, for creating a small basic Puppy to use as a foundation for derivatives. But that doesn't impact the use of SVN at all. I also have ideas about modifying Unleashed to make it easier to work on a derivative long term, across multiple versions of Puppy. That would require some structural changes to Uneashed, but only slight changes to the SVN tree (mainly moving a couple directories around).
Between depriving a man of one hour from his life and depriving him of his life there exists only a difference of degree. --Muad'Dib
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Joined: 20 May 2006
Posts: 6850
Location: Auckland, New Zealand
Posted: Tue 04 Nov 2008, 00:36
Post subject:
SF seems to be painfully slow to browse anyway (at least around here). Will this be browseable (in a browser, rather than an SVN client)?
What exactly is/will be the connection between the unleashed SVN and the petget repository?
I'm thinking it will get quite a bit bigger, as it will include all the files for petget, and we will probably want to move from everyone posting .pets on the forum to actually making official .pets instead. Or will it not include everything?
Do you know a good
program? Please post a link
Classic Puppy quotes
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Joined: 04 May 2005
Posts: 6266
Location: Knoxville, TN, USA
Posted: Tue 04 Nov 2008, 03:06
Post subject:
Browser-browsablility is a definite goal. Right now I'm focusing on just the basic server aspect though, since that's the part that really matters. My homework, need for sleep, and the shipment of LEGO gears and pneumatic pistons that just arrived limit my time somewhat. (Must exercise my willpower for a while and refuse to open that package until more important things are done.)
As for SVN vs PETget: SVN is the development area. When a stable version of Puppy is ready, it would be "tagged", which is basically just a way to mark that particular revision as being special and giving it a name. Then that revision would be used to build the .iso files, and the package directories would be compressed, turned into .pet packages, and uploaded to the normal file server.
Between versions of Puppy, one could checkout a package from the SVN to get the latest changes. It would come out extracted though, so to install it you'd have to either copy it into your filesystem manually, or turn the directory into a .pet package (easy, just
tar czf package-1.2.3.tar.gz package-1.2.3; tgz2pet package-1.2.3.tar.gz
) and install it that way. Or I believe you could have SVN generate diff files for the changes between the stable version and the current revision, then just apply those.
I'm thinking it will get quite a bit bigger, as it will include all the files for petget, and we will probably want to move from everyone posting .pets on the forum to actually making official .pets instead. Or will it not include everything?
Hmmm.... I guess it depends on how we do the normal repositories. Currently, the SVN repo would hold all the "official" packages, and therefor so would the normal PETget repo. We definitely wouldn't want to start having everybody make pets that go into the SVN repo. That would make things too big. I think if we ever set up a larger more formal repository system, we'd probably need to modify the idea of the "official" pets. Rather than have a good number of stuff we never plan to use officially, we'd want to just keep the stuff we are using or considering using. When we finish and upload the isos, we'd also upload all the packages we used, along with any we considered using that have notable changes from the "stock" versions in the normal repository. They'd mainly be for people making derivatives, or to add in the "deleted scenes" that the devs didn't include. The package manager would mainly be oriented at what you could call the third-party repository, but at that point I think it would be more of a first or second party repo (can you have a second-party repo?) where the stuff has gone through some kind of quality control.
Between depriving a man of one hour from his life and depriving him of his life there exists only a difference of degree. --Muad'Dib
Last edited by Pizzasgood on Tue 04 Nov 2008, 03:19; edited 1 time in total
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Official Crustacean
Joined: 04 May 2005
Posts: 15239
Location: Paradox Realm
Posted: Tue 04 Nov 2008, 03:15
Post subject:
I think Google also hosts some open source projects?
YinYana AI Buddhism
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Joined: 26 May 2006
Posts: 2946
Location: Southampton, UK
Posted: Tue 04 Nov 2008, 04:05
Post subject:
I think Google also hosts some open source projects?
google ToS wrote:
Users residing in countries on the United States Office of Foreign Assets Control sanction list, including Cuba, Iran, Libya, North Korea, Sudan and Syria, may not post or access Content available through the Google Code website.
Do the US government rules apply to all software or just that related to encryption? Is the onus on the website owner to prevent such access?
community website
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Joined: 28 Jan 2007
Posts: 1169
Location: USA
Posted: Tue 04 Nov 2008, 10:29
Post subject:
the only reason unleashed is so huge is that it includes the kernel... that is a binary package and should not be included
unleashed should consist of ONLY the build scripts as those chance little between versions
kernels should not be in unleashed
Taking Puppy Linux to the limit of perfection. meanwhile try "puppy pfix=duct_tape" kernel parem eater.
X86: Sager NP6110 3630QM 16GB ram, Tyan Thunder 2 2x 300Mhz
Sun: SS2 , LX , SS5 , SS10 , SS20 ,Ultra 1, Ultra 10 , T2000
Mac: Platinum Plus, SE/30
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Joined: 04 May 2005
Posts: 6266
Location: Knoxville, TN, USA
Posted: Wed 05 Nov 2008, 00:36
Post subject:
I don't think you're getting it yet.
the only reason unleashed is so huge is that it includes the kernel... that is a binary package and should not be included
That's the main reason that the unleashed_core
is big, yes.
I'm not talking about only that package. I'm talking about the ENTIRE tree. As in, you've downoaded and extracted the unleashed_core, and then you've downloaded and extracted every .pet package from the petget repo and placed them in the tree. Now you're ready to start changing things.
At that point, the kernel stuff uses around 135 MB in Puppy 4.1's tree. The packages/ directory amounts for 858 MB.
But fortunately, SVN shrinks the entire 996 MB (including the non-kernel and non-packages/ stuff) down to around 270 MB.
Also, it seems that the bandwidth used to check out the trunk is also ~270 MB. Which means that you probably wouldn't save any bandwidth with the long convoluted mess I've been planning, where you'd grab the packages from the package server and overlay the SVN over them. However, doing that could get you better download speeds, especially right now while this is running from an old computer stashed under my bed...
Unfortunately, it seems that when you do the checkout and set up a working copy of that same data, the working copy expands to about 1.7 GB. I found that surprising, but I don't think it's a deal breaker.
Now that I have everything finished, when I get some more free time I can start seeing how it grows.
You should now be able to access the repo (through svn only) at svn://pizzasgood.no-ip.org/puppy, or svn://18.104.22.168/puppy, whichever floats your boat. I haven't gotten an opportunity to test this from off campus so I'm not entirely sure it will work, but I think it does. A word of warning: if nobody has accessed it in a while, it will probably hang for a bit when you first try to connect, until the lazy machine wakes up and restarts the harddrive. When I've finished experimenting with growth rates I'll look into setting up a web frontend.
If you're interested in navigating around in it, without actually checking anything out, you may be interested to hear that SVN has an "ls" option.
svn ls svn://pizzasgood.no-ip.org/puppy/
That way you can see what there is to see see see.
Read access is currently anonymous.
For write access, you need to log in.
: testperson
: irnotreelyo
If you don't specifically give it parameters telling it who you are, it will probably ask you for the root password. Just hit enter, and it will give you a chance to input the username. Once you put int the username and password, your local svn client will cache that in /root/.subversion so that you don't have to enter it again. You can disable that in a configuration file somewhere.
I haven't set up the scripts to automate the first checkout yet, and as I said above, it turns out it's only a ~270 MB download to checkout the entire trunk. So you can either do that, or you can check out specific directories, files, etc. (Use the --depth=immediates option if you only want a specific level of the filesystem, without grabbing everything in its subdirectories).
Note - when I've said things like "check out the whole thing" I actually only meant the whole trunk. Do NOT check out the entire repository. That would involve also checking out every tagged version and every active branch. In this case, there are no branches yet and only one tagged version, so you'd "only" double your download size. In the future, and in other people's SVN repositories, there could be ten different tagged versions!
Assuming you want to check out the trunk to /mnt/sda4/puppy_svn_trunk, you would do this:
svn co svn://pizzasgood.no-ip.org/puppy/trunk /mnt/sda4/puppy_svn_trunk
If instead, you only wanted 0rootfs_skeleton-410, you would do something like this:
svn co svn://pizzasgood.no-ip.org/puppy/trunk/packages/0rootfs_skeleton-410 /mnt/sda4/0rootfs_skeleton-410
Then you can go in there and mess around. Don't mess with the .svn directories, you'll confuse SVN.
Here are links to more info on using SVN:
Here is the current layout of the repo:
bash-3.00# tree -d -L 4
`-- puppy
|-- branches
|-- tags
| `-- demo-1.00
| |-- packages
| `-- puppy-unleashed
`-- trunk
|-- packages
| |-- 0pkgs_db-4.00
| |-- 0pkgs_db-4.10
| |-- 0rootfs_skeleton-4.00
| |-- 0rootfs_skeleton-410
| |-- 915resolution-0.5.3-patched409
| |-- zip-232
| |-- zlib-1.2.3
| `-- zmixer-0.2.1
`-- puppy-unleashed
|-- boot
|-- isolinux-builds
|-- kernels
`-- packages -> ../packages
If you cannot connect to the repository, please tell me exactly what you did, how it behaved, and any error messages it gave (copy-paste directly from rxvt if possible). If the "pretty" address doesn't work, try the ip address. Also, see if you can attempt to connect to my ssh (ssh pizzasgood.no-ip.org). Obviously you won't have much chance of actually logging in through ssh, but it should at least say something like "permission denied". But do be aware that after you try five times, my computer will ignore your attempts at connecting with ssh for fifteen minutes or so. So don't let that confuse you. (No, it doesn't do that with SVN, only SSH).
And like I mentioned above, also be aware that it may take 10-20 seconds for my computer to get off it's lazy rear. I just wrote and started a simple bandwidth logging daemon, so maybe that will avoid this. Anyways, don't assume it isn't working until you actually get a timeout error.
Between depriving a man of one hour from his life and depriving him of his life there exists only a difference of degree. --Muad'Dib
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Joined: 26 May 2006
Posts: 2946
Location: Southampton, UK
Posted: Wed 05 Nov 2008, 06:14
Post subject:
Looking good
I checked out one of the absvolume packages
added a new file
and committed my changes
all looks rosy
As I was playing with svn I also had a look at retrovol. I like the look of the sliders and the desired feature list is impressive.
community website
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Joined: 25 May 2005
Posts: 4839
Location: Manila
Posted: Wed 05 Nov 2008, 07:35
Post subject: subversion client
Subversion client 1.3.1 is a pet package for Puppy 2 up to Puppy 3, so it is easy to add, no reboot required.
This helped me with a quick intro and commands:
Made a checkout (without target work area) and 8 MB of the trunk/unleashed got into /root/puppy. Transfer is a bit slow, but it's early evening here and that's expected.
Puppy user since Oct 2004. Want FreeOffice?
Get the sfs (English only)
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Official Crustacean
Joined: 04 May 2005
Posts: 15239
Location: Paradox Realm
Posted: Wed 05 Nov 2008, 09:39
Post subject: Re: subversion client
raffy wrote:
Puppy 3, so it is easy to add, no reboot required.
Thanks Raffy - I installed using Puppy 4.1.1 package manager (the SVN is under
version 3 pets
) and was able to use a few command lines immediately. I then got 'the fear of geek' and need to know if there is an SVN front end?
At one time we did have some sort of revisioning system in Puppy main - what was it? Did it have a front end? It seems there is a serious and determined recognition by major developers that revisioning is essential. Good news
There have been several previous attempts. I looked at a few myself. No real multi-developer support and so it never caught on. This time I am very hopeful.
It might be of interest a revisioning system I was involved in developing for the CURL language.
Curl is a language most comparable to PHP or possibly XUL
- however XUL is not available for Opera - so PHP is the better option.
Everything was done from a web interface.
We had two trees displayed in a webpage
The local and the remote. Once designated as a developer, you could download and work on a file locally and decide when it was ready to upload. You could also leave messages or notes about what you were doing etc. We kind of developed and used the system simultaneously.
Anyway feel free to use the 'Tick' name and logo if useful.
YinYana AI Buddhism
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text:
While global demand has been weak for Whirlpool, CEO Jeff Fettig said on Friday he's optimistic that a rebound in the U.S. housing market and consumers' need to replace old appliances will boost sales during the next three to five years.
"This is another year, where we're bouncing along the bottom in terms of demand from a recessionary level — down about 25 percent from the high in 2006," said Fettig of the sluggish U.S. market. The company is forecasting another 1 to 2 percent decline this year as consumers make few discretionary appliance purchases.
Europe and Asia have also been weak, while Latin America has proven to be a strong market for Whirlpool.


text:
Trading and gambling are similar in that they both attempt to create a capital gain, over a relatively short period of time, without creating new wealth. If I am a shoemaker, then my efforts create a pair of shoes that someone else can wear (new wealth), while I earn an income from cobbling. When I am a trader or gambler, I may earn an income, but there is no additional wealth created. Some markets experts would claim traders create market liquidity to the benefit of long-term investors, and that this in itself has value, similar to "new wealth" creation. But because trading and gambling involve capital transfer without capital creation they are viewed skeptically, especially when their outcomes are unpredictable. Society generally prefers the shoemaker-type endeavor because it creates something others find valuable.
Trading and gambling are both fundamentally stochastic, that is unpredictable, and because of this they are often viewed negatively. We feel an "honest effort" has more predictability to it, and we may hold those who take too much risk in disdain. However, many who have tried their hand at a new business will attest to significant luck when successful. The goal of new wealth creation, and the time needed to develop a successful business, act to mitigate the risks involved. But then, traders and gamblers will often describe many years of practice before becoming successful.
Trading and gambling both occur because, at least at their start, the participants have accrued wealth in excess of what they need to live. This is similar to the investor who possesses excess capital (and typically much more than the average trader or gambler). Investing has a connotation preferable to trading because the investor is viewed as enabling new wealth creation and because it involves delayed gratification – the benefits of a sound investment may take many years to realize – just those attributes described above. There seems to be an inherent respect for a long-term investment that turns out well: The successful investor is considered patient and prescient. On the other hand, trading and gambling have a get-rich-quick aura to them and are often viewed with disdain because of it. In fact, a professional trader or gambler may not get rich quickly, but simply earn income slowly over time.
When modern civilization enabled some individuals to amass wealth in excess to what was needed immediately to survive, speculative trading and gambling naturally evolved, and traders and gamblers may be viewed negatively because they are using money that others do not have. Because no one has yet determined an equitable means of evenly distributing wealth, trading and gambling should not be considered inherently evil. No one objects to an employee retirement fund investing in the stock market: The capital has been amassed and must be somehow managed.
Successful traders and gamblers are typically highly skilled and spend years becoming proficient. Success often means a steady regular income and not a one-time jackpot event. Because society values most activities that require a highly-developed skill, the successful trader or gambler will be viewed in a positive light, while the failed participant is merely seen as one more "loser."
Both trading and gambling have seen the development of numerous mathematical (and pseudo-mathematical) techniques in order to increase their chances of success. Because the mathematics of trading and gambling can be made precise and add to our understanding of natural events, there is new wealth creation from those who have contributed to defining profitable trading and gambling techniques. Often these individuals are held in esteem while the practitioners of the techniques are not. For example, the Nobel Economics Prize was awarded to the inventors of the Black-Scholes options pricing model, while those who daily use the model's outputs are viewed merely as traders.
So much for a broad-brush outline of the similarities of trading and gambling; what of their differences?


text:
POSTED: Jul 18, 2013 8:00 PM ET
SACRAMENTO, Calif. (AP) — The Sacramento Kings have signed second-round draft pick Ray McCallum.
General manager Pete D'Alessandro announced the move Thursday.
McCallum was drafted 36th overall last month out of the University of Detroit. The guard averaged 15.9 points, 4.8 rebounds and 4.4 assists over three college seasons. He was a three-time All-Horizon league selection and the conference's player of the year last season.


text:
* MSCI Asia ex-Japan drops as tech-heavy Seoul shares dip
* Nikkei surges as the yen hits fresh lows vs dollar and
* Samsung Electronics posts record profit, cautious on capex
* Positive economic outlook supports copper, limits oil loss
By Chikako Mogi
TOKYO, Jan 25 (Reuters) - Asian shares fell on Friday, hurt
by a drop in regional technology stocks and on caution ahead of
the corporate earnings season, but gains in Japan and Australia
limited overall losses for equities.
Upbeat manufacturing reports from the United States, Germany
and China underpinned sentiment for other assets, supporting
copper while curbing selling pressure in oil.
"The PMI indicators from the U.S., Europe and China should
serve to keep markets tracking higher," said CMC Markets senior
trader Tim Waterer in Sydney.
The MSCI's broadest index of Asia-Pacific shares outside
Japan eased 0.5 percent, and was set for a
weekly drop of 1 percent, its biggest such loss in two months.
A 1.4 percent slide in the technology sector
dragged the pan-Asian index down, as tech-heavy markets such as
South Korea and Taiwan fell.
Seoul shares declined 0.9 percent, weighed by weak
profits for automakers, while tech shares continued to falter as
Samsung Electronics announced cautious spending
plans for the first time since the global financial crisis.
Shares of Apple Inc's suppliers extended their
declines after Apple's below-estimate results announced earlier
in the week: Taiwan's Largan Precision weakened and
Samsung shares shed as much as 3.3 percent.
Hong Kong and Shanghai were the other
laggards as investors took profits from recent rallies and
remained cautious ahead of the upcoming earnings season.
A 0.3 percent rise in London copper to $8,118 a
tonne and gold prices steadying around $1,669 an ounce
helped push commodity-reliant Australian shares up 0.5
percent to a fresh 21-month high, marking an eighth straight
session of gains.
U.S. crude eased 0.1 percent to $95.87 a barrel and
Brent inched down 0.2 percent to $113.11.
"It now seems that the stronger tone in global equity
markets, coupled with a notable easing in European and US market
tensions, is leading to short-term pressure on gold," said Ed
Meir, an analyst at INTL FCStone, in a research note.
European markets are seen falling, with financial
spread-betters predicting London's FTSE 100, Paris's
CAC-40 and Frankfurt's DAX would open down as
much as 0.4 percent. U.S. stock futures were down 0.2
percent, pointing to a softer Wall Street start.
Japan's Nikkei stock average outperformed its Asian
peers with a 2.9 percent surge as the yen hit fresh lows versus
the dollar and the euro on expectations Japan will continue to
pursue bold policies to beat deflation and stimulate growth.
The Nikkei rose for an 11th straight week.
"Trading on Japan is gaining momentum among foreign
investors, centering around the dollar/yen, which has dictated
Nikkei's direction," said Tetsuro Ii, the chief executive of
Commons Asset Management.
The yen's slide bolsters sentiment for Japanese equities as
it lifts earnings prospects for exporters, ahead of the
quarterly earnings season set to start next week.
The dollar scaled its highest level since June 2010
to reach 90.695 yen early on Friday and the euro rose
to 121.32, its highest since April 2011. Prime Minister Shinzo
Abe's new administration has made clear it wants a weaker yen,
providing investors a reason to short the currency.
More than 80 percent of Japanese firms are in favour of
Abe's drive for aggressive monetary easing and huge fiscal
spending, though most also feared Japan would face a debt crisis
within a few years, according to a Reuters poll.
The yen's two-month decline has more legs, many traders and
analysts believe, noting the yen has barely caught up to levels
before a potential debt default by Greece sparked the euro zone
debt crisis and sent the euro plummeting nearly three years ago.
The yen was around 95 yen against the dollar and 123 yen
against the euro early in May 2010 when protests flared up in
Greece against its austerity steps in exchange for a bailout.
Despite the recent rallies, the Nikkei remains well below
levels before the 2008 financial crisis while the Standard &
Poor's 500 Index and Germany's benchmark stock index have
both already exceeded that level, thanks to the weakness of the
euro and the dollar, measured against a basket of currencies.
"JPY weakness should continue over the coming year driven by
an expansion of the Bank of Japan's balance sheet relative to
the European Central Bank and the Federal Reserve," said Kit
Juckes, FX strategist at Societe Generale in a note. "I don't
know how long the USD/JPY is going to pause at around 90, but a
move to 100 still seems very likely in the longer run."


text:
Top NH Golfers Tee Off
Allen Lessels' NH Golf: Harrity, 'kids' ready for women's State AmBy ALLEN LESSELS
New Hampshire Union Leader
July 27. 2013 3:23PM
Dana Harrity of Rye won her first New Hampshire Women's Golf Association State Amateur championship at Abenaqui Country Club, her home course, in 1982.
She bookended that initial title with her latest at Hanover Country Club last year and the state's premier female golfer over the last three decades has won exactly half of the championships contended in the last 30 years.
But that sparkling resume doesn't make her the favorite heading into this year's 54-hole women's State Am, scheduled for Tuesday, Wednesday and Thursday at the Nashua Country Club, Harrity feels.
"I'm playing fine and I'm the defending champion," Harrity said last week. "But I feel as though this year's tournament really belongs to the younger players."
The list of top contenders starts with Tracy Martin, Harrity feels, and includes folks such as Tara Watt, who won the tournament in 2011, Tracy Marshall, Lisanne Schmidt of Grantham and her younger sisters, Alex and Colette, among others.
"There are some great kids out there," Harrity said. "We're very fortunate to have some really nice kids playing."
One young player who is not entered this week at the State Am is Lauren Thibodeau, the 13-year-old out of Hampstead and Windham Country Club who won her third straight junior title last month.
Thibodeau finished 10th last year at Hanover and shot a 75 on the second day of the tournament.
Martin plays out of Nashua and tied for second in the New England Amateur earlier this month at Renaissance in Haverhill, Mass. She's from Tyngsborough, Mass., and starred at Bishop Guertin of Nashua. She just wrapped up her collegiate career at the University of Richmond with the second-lowest career scoring average (78.44) in the program's history.
"She hasn't played the State Am in ages and she's playing really well," Harrity said.
Harrity gets no argument from Nashua Country Club pro Dick Dichard on the assessment of Martin as the favorite.
"She's playing well and she definitely knows the greens," Dichard said. "And, in fact, she's really stepped up her game in the last month. She's breaking par regularly and she had a hole-in-one and the best round I know of going back to the Pat Bradley days."
Martin shot a 66 at Nashua a couple of weeks ago and that may be a record, Dichard said.
"I can't remember that Pat Bradley (the LPGA standout and a World Golf Hall of Famer) shot a 66," Dichard said.
Marshall, who is a member at Abenaqui with Harrity, led last year's tournament on the final hole and needed a par to close it out She ran into all kinds of problems and carded a 10 on it.
"She got stuck in a bad spot and didn't think clearly about how to get out of it," Harrity said. "She learned from that and she hits it a long way. She's a great kid. She's a contender. She's going to be a factor."
Harrity, 54, could well be, too, of course.
"I think I'm going to be competitive, but I just don't know," she said. "I didn't play well in New Englands, but I wasn't feeling well and you never know. I have a tendency to play better in State Ams then in normal tournaments. I think I concentrate harder."
She gives up yardage off the tee to some of the big-hitting younger players, but feels Nashua suits her game.
"I don't feel you have to be too long and I think I can score well there," she said. "The greens are quite quick. It will be about chipping and putting and obviously if you're going into them with wedges, it's much better than if you're going in with a 6-iron, but it's still doable."
Lisanne Schmidt doesn't count Harrity out.
"Dana's just a phenomenal player," she said. "She's so consistent. She doesn't shoot 65, but she's very consistent and so good at what she does. I love playing in golf tournaments with her. She really loves the game. It's great to have a role model like Dana and for her to win the tournament is totally doable. You don't need to be 25 to win the state tournament."
There are 84 golfers in the tournament and after the first 36 holes the field will be cut to 60 and ties for the final 18.
email@example.com On twitter: @AllenLessels


text:
Thalian Hall's new digital projection system will get a workout
Thalian Hall's new digital projection system will get a workout from "Renoir," a flawed but gorgeous French film about the last days of the great Impressionist painter that's screening at the Cinematique film series next week.
The year is 1915; effigies of the German Kaiser hang from trees. The place: the village of Cagnes-sur-Mer in a mountainous corner of France's Mediterranean coast. In a splash of color, a girl in an orange dress is cycling down a country road.
The young woman, we soon learn, is Andr�e Heuschling, or "Deedee," a sometime actress who is seeking out Renoir to apply for work as a model – supposedly on the recommendation of the painter's wife.
This mildly astonishes the inhabitants of the Renoir household since Madame Renoir is dead. It turns out (though the film doesn't explain this) that Aline Renoir had passed away in May 1915, so it's just possible that she and Deedee had spoken. In the film, Madame Renoir's ghost briefly appears to her husband in his sleep, asking how the new model is working out.
As it turns out, amazingly well. By 1915, Renoir was in his 70s, crippled by rheumatoid arthritis, confined to a wheelchair, his hands knobbed and gnarled. He was still painting, though, and in the movie, Deedee becomes his muse, inspiring a remarkable late series of paintings of bathers that were among his greatest works.
Deedee inspires others as well. About 20 minutes into the film, the painter's middle son, Jean, comes limping home from World War I. Jean is already tinkering with cameras and film projectors. Deedee, who quickly becomes his lover, pushes him to become a director.
Jean Renoir would go on to become one of France's greatest filmmakers, creating such classics as "La Grande Illusion" and "Rules of the Game." DeeDee, under the stage name Catherine Hessling, would become his first wife and first star.
And that's about it. Nothing much happens in "Renoir," although a lot seems about to happen. The director and co-screenwriter, Gilles Bourdos, is known in France for his thrillers, but this movie deliberately stomps out suspense the moment it lifts its head.
Threads of plot – like the supernatural aspect of Deedee's arrival – are picked up, only to be dropped a few minutes later. Early on, there's sexual tension between Deedee and the painter's youngest son, Claude, or Coco, a surly pre-teen who stomps around the Renoir estate angrily slashing at grass with a stick. Once Jean arrives, however, Coco slips into the background.
Deedee's free-spirit personality never quite jells, although the movie points out the tension between who she is and the idealized woman Jean and his father would like her to be.
Two things salvage "Renoir": the camera work and the acting.
Bourdos and Korean cinematographer Mark Ping Bing Lee go to great lengths to recreate the vivid colors of Renoir's palette. After watching the blue murk that predominates in most CGI-spectacular movies these days, watching "Renoir" is like stepping outside on a bright day out of a darkened movie house.
Strong performances help, notably from Michel Bouquet, the 87-year-old veteran of so many Francois Truffaut films. He plays the aged Renoir as an intriguing mixture of grumpy old man, pixie and Zen master, still exercising a sort of dominion over a court of mysterious female servants who wait on "the Boss."
In French, with English subtitles, "Renoir" is rated "R." Theret and the other models in the cast spend much of the movie in the nude.
Ben Steelman: 343-2208


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Author Archives
Pep Band Formed at EMU
This year EMU will welcome the Pep Band at home basketball games. The Pep Band, which is comprised of EMU students, will be playing during half-times, timeouts, and also preceding games. "Everyone in the EMU community should be super pumped… Read More ›
Housing Equality Meeting Raises Issues, Questions
Luke Hartman, Vice President for Enrollment, and Gloria Rhodes, Chair of the Department of Applied Social Sciences, brought together a group of students and staff to discuss housing equity at EMU last Tuesday. Hartman invited staff members from Residence Life,… Read More ›
(Re)Imagining Masculinity Challenges Men to do More
As part of Take Back the Night, four men came together to talk last Wednesday about societal pressure on men and what it means to be masculine. Sophomore Matej Gligorevic, Senior Nathanael Ressler, CJP student Andrew Daniels, and Community Member… Read More ›
Word From the District: Tech Industry Grows in D.C.
When many people think of the center of this country's technology industry, they often think of Silicon Valley. The east has yet to develop a tech giant. However, D.C. seems to be on its way to becoming that giant. Last… Read More ›
Faculty Feature: Hill's Compassion Guides Her Life
All of the work to get young minds admitted into Eastern Mennonite University starts with Gwen Hill. She arranges the tours and helps keep the admissions office running smoothly and efficiently. Gwen Hill is known for her compassion, which is… Read More ›
A Day of Exploration Through the Country's Capital
Students with groggy expressions boarded a charter bus in the early hours of the morning on Saturday, Nov. 7. Normally most of us would spend our weekends in bed catching up on sleep, but the opportunity of visiting Washington D.C…. Read More ›
Virginia Film Festival Progresses From Broken to Hopeful
When attending the Virginia Film Festival, or any film festival really, the guide to having a good time rests with the movies you choose and the order in which you see them. As you view three movies back to back… Read More ›
Royals' Weekly Recap 11/12/15
The Men's Soccer team played Washington and Lee University last week, resulting in a 2-0 loss. Daniel Nyce recorded 13 saves. Jake Lind, Emmanuel Boamah, and Jonathan Bush each recorded one shot. This concludes the men's soccer season with a… Read More ›
Reflections from an Athlete: Travis Hull
I love EMU golf. I love the opportunity and the challenge. I know most people do not see golf as a team sport if they only know about professional golf tours, but those who play the sport would say otherwise…. Read More ›
Women's Basketball Team Bounces To Second In Poll
With a successful 2014-2015 season, Eastern Mennonite University's women's basketball team is picked second in the ODAC Preseason Poll. Last season, the women's team finished the season with 23 wins and 5 losses. 15 of those games were conference wins…. Read More ›


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Project Soul Guru Tuesday 09/10/2012, 10:36
So i was reading the comments on the LD cards and some of them extend to like 10-12 pages of complaints of how bad they are and have to work really hard for an unusable card and most wanting to have them remade. Such as Scott , Lianah , some how ever are good like Futoshi and Bonnie.
So what do you guys think of this?
Thoazol Moderator Wise Men Distracted Tuesday 09/10/2012, 18:04
Remaking Ld's? To the point of the weakest one (Naja, Scott, maybe Lianah and Bella) being at least on par with the average cards. Or unique. Power = Power opp +2, or something would do it for Naja.
10 to 12 pages of complaints? There's a lot of same arguments, lot of arguments without reasoning, some downright outrageous arguments (8/4 and -4 opp dmg, min 2). Not to mention the spam such as the guy sitting on the can. That's one of the venues that should be cleaned up.
UM_AaaBattery Moderator URBAN MADNESS Tuesday 09/10/2012, 21:19
I personally find the Lds fine, they are all usable. Also they are Free so theres not much to complain about.
Project Soul Guru Wednesday 10/10/2012, 02:16
I find all comments amusing to read for some reason lol some are quite hilarious
Zero Guru Harbingers of Ares Wednesday 10/10/2012, 11:22
I think they should put some sort of uniqueness or at least something cool about the card.
Like Scott Ld is trying to take down the GHEIST while jaxx is responsible for the rescue clan.
thats pretty awesome.
Or like thoazol said, some cool abilities.
Or just some downright hilarious cards.... like 1/1 Attack + 25 or a new clan thats stats are like all 8/8 and they're abilities are all backlash??
Whatever it is i think some lds are an excuse to be honest. Like bikini joe ld , whats so special about him???
I definitely like what they did with Lds but i do think they should remake them
mahawirasd Imperator Immortality Friday 12/10/2012, 06:33
Scott is actually quite OK imho. He's that DR bluff that can potentially deal decent damage without any pill invested.
Lianah is a good filler as well as low pill bluff.
I'd have to agree with Zro that bikini joe is borderline useless, but at least his art is enjoyable hahah
+1 Thoazol and project regarding the comments
Sure some of them only have niche uses, but the missions itself are oft times fun and i definitely won't complain about the 10 credits TEE HEE
Pilluminati Titan URBAN MADNESS Friday 12/10/2012, 17:50
Yeah,some lds do suck,admittedly; i don't think i have any use for a bella ld or fhtagn ld or kreenk ld to be honest. Their stories are just ho-hum average-joe stories that nobody would pay attention to if they were just regular new blood filler pieces,but as these card were released in the really early stages of the ld releases,i think the devs noticed that these cards really do suck in every aspect of being a card,and that's visably noticeable when you see the order of cards and as it goes down,the newer ones at least are interesting if not useful.But,i dont think they should be remade. They are what they are,and they probably wouldn't be much better off for it aside from being the flavor of the month and being dropped down to fifth best in their respective clan star position depth chart.It's a reason why im not exactly in favor of changing diego or pulsar or ogoun kyu to updated stats or at least an ability because they lose that reputation(some will say notoriety) of being that terrible card and just be another mediocre card with 10 comments on it.Besides,whether you like it or not,you'll have to use them anyway as they all get missions now
On a related note though,Bikini joe ld is pretty useless,but his story is actually pretty entertaining,so i would say the jury it out on him as an overall card.
But hey,since new clans come out every year and consequently so does a new ld,might as well save the debate for then,right?


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News Posts
A Hornbill Spoon
by AMNH on
For much of human history, poisoning—whether by accident or malice—was much more common than it is today. How was the hornbill spoon used to protect against the threat?
CT Scans of Baby Mammoth Mummies Yield Trove of Insights
by AMNH on
Three-dimensional scans of two mummified newborn woolly mammoths recovered from the Siberian Arctic are revealing previously inaccessible details about the early development of prehistoric proboscideans.
Manhattanhenge Returns
by AMNH on
Manhattanhenge returns for the last time this Friday and Saturday, July 11-12, 2014. Here is what you need to know:
Blue Whale: Watch the Whale Wash
by AMNH on
Each year, the Museum's blue whale model gets spruced up in an annual scrubdown. The 2014 Whale Wash is happening this week, from Monday through Wednesday.
New 3D Film: Great White Shark
by AMNH on
Sightings of great white sharkshave been reported at the Museum! In the Samuel J. and Ethel LeFrak Theater, the new large-format film Great White Shark is now playing in 3D digital and 2D.


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Skip to Content
Work Study is need-based financial aid programs that give students the opportunity to work part-time while going to school. Work Study students can therefore find jobs and may be able to keep their loan debt down by earning part of their aid eligibility, rather than borrowing more loans.
If work study is not listed as an award on the letter, students are welcome to come in or call the Financial Aid and Scholarship Office to investigate their eligibility. You may also visit the UW Guide to Work Study for more information.
UW Work Study
For on-campus jobs, look for jobs with "Bothell Campus" listed as the department name.


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WebVet Online allows Veterinarians to use a Web form to store vaccinations they have administered and licenses they sold. Veterinarians must sign in and be registered with Animal Care and Regulation's online site before processing records. For more information and registration, contact Broward County Animal Care and Regulation at 954-359-1314.
You are leaving the Official Site of Broward County, Florida. The County provides links to information created and maintained by other public and/or private organizations for your convenience. As described in the Terms of Use, the County does not promote or endorse non-County links.
If your browser doesn't automatically redirect within ten seconds, click here.


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How cool would it be to travel from Philadelphia to New York in 37 minutes? I don't know. Truth is, we may never know. I would put high-speed rail -- the subject of an interesting multi-part series that began in the Inquirer today -- near the top of the great ideas of 2008 that is surely getting lost in the kill-all-government-spending-except-the-Bush-and-Obama-wars-and-Bush-tax-cuts-for-the-rich frenzy of 2010.
As I'm sure Glenn Beck will say sometime in the near future, show me one place where the Founding Fathers said anything about high-speed rail!!!
Here's the crux:
Want to go from Los Angeles to San Francisco in two hours, 40 minutes? Or from Philadelphia to Pittsburgh in 21/2 hours? Or from Philadelphia to New York in 37 minutes?
Want to cut carbon-dioxide emissions by 71 percent per passenger-mile compared with car travel, or 76 percent compared with air travel?
Want to cut travel fatalities to zero? That's how many people have died in high-speed train accidents in France or Spain or Japan.
Want to escape airport security lines? Want to get out of seat belts? Want to elude traffic gridlock?
Want to spend $10 billion a year?
To the Tea Party crowd, you lost them at $10 billion. What a shame. This is a program that would create literally thousands of manufacturing jobs in the private sector in the United States, as contracts are awarded, and then would create thousands more jobs for mechanics to maintain the trains and the tracks, and for people to operate the system once it is running. Frankly, the global warming and traffic and safety benefits, while importantly, are tangential to the jobs right now. But it doesn't really matter because America has lost its nerve, especially our leaders.
One other quote from the article stuck with me:
"This is what the rest of the world is doing," said Robert Yaro, an urban planning professor at the University of Pennsylvania and president of the Regional Plan Association, a New York-area research group. "We're behind not only France and Spain and the U.K. and Japan and China and Korea, but now Morocco and India and Vietnam are building high-speed rail. This is what we have to do.
The rest of the world isn't paralyzed by fear.


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Latest update : 2012-05-28
Egypt after the revolution
Egypt has just held the first free and democratic presidential election of its history. The run-off will take place mid-June. A few days before this historic vote, France 24 went to meet Egyptian voters.
Has the revolution achieved its goals? What challenges will the new president face? With a new chapter of Egyptian history about to be written, our reporters Willy Bracciano and Khalil Béchir went to meet the population shortly before polling day.
The result of these elections will be crucial for the future direction of the Arab world's most populous country. Currently, it appears torn between the temptation of voting for Islamist candidates and ones who promise normality, paradoxically embodied by figures from the Mubarak era.
Some thought the departure of Hosni Mubarak over a year ago would resolve everything. And yet every day there are new protests against the ruling military council who run the country. Every day, the population is calling for solutions to the problems of everyday life, to the economic crisis, to unemployment and to corruption.
Meanwhile, many are wondering about the successes and failures of the revolution. Fifteen months after the first protests on Tahrir Square, we take you to the heart of Egyptian society. We travel to Cairo, to Suez -- the birthplace of the revolution -- and to Luxor, one of the main tourist sites affected by the upheaval.


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Game Leaders
Team Stats
Passing Yards
Rushing Yards
Time of Poss.
ASHLAND, VA -- Randolph-Macon College Football got a three yard touchdown run and a two-point conversion from Thaddeus Scruggs with 4:37 to go in the game to come away with a 36-29 victory over visiting Shenandoah Saturday afternoon.
Scruggs ran for 119 yards and two scores on the day for R-MC, which is now 3-0 for the second consecutive year and just the second time since the 1986 season. Shenandoah, which will join the ODAC next season, drops to 1-2 on the season.
A Jeremy Bowry interception set up the Jackets for the first score of the game when he picked off SU quarterback Daniel Wright and it returned to the Hornets 12 yard line. Three plays later, Jackets quarterback Zac Naccarato scored on an eight yard bootleg.
SU scored its first touchdown of the day on the first play of the second quarter when Wright found Rico Wallace on a 27 yard touchdown pass.
A 14 yard run by Scruggs pushed the Jackets ahead 14-7 and capped a 12 play, 69 yard drive with just 1:15 to go in the half.
The Hornets got the kick off and answered right back 59 seconds later, when Wright found Qiydaar Murphy on a 15 yard scoring strike, sending the teams to the locker room tied 14-14.
After holding R-MC on its first possession of the second half, SU needed just three plays before Wright hooked up with Wallace for a 53 yard pass to push SU ahead 21-14.
On R-MC's ensuing possession, Scruggs ran the ball six times for 47 yards and Naccarato found the end zone on an eight yard scramble to tie the game.
A Chris Pace interception of Wright later in the third quarter gave R-MC the ball at the one yard line and Naccarato plunged for in for the score to pull R-MC ahead 28-21 with just under four minutes to go in the third quarter.
Shenandoah was able to cut the lead to 28-23 on a safety with just over 10 minutes to play and then took the ball back and drove 60 yards on five plays, making the score 29-28.
R-MC took over on its ensuing drive and used five straight runs by Drake Sanders to moved 34 yards down to the Shenandoah 15 yard line. From there, Scruggs rushed for a 12 yard gain, then the three yard scamper that proved to be the game-winner.
Bowry finished the day with nine tackles, including eight solo. David Fetter and Patrick Moses each had eight stops on the day as well for R-MC.
Randolph-Macon will cap its ODAC schedule next Saturday after Frostburg State. Kickoff is slated for 1:00 p.m.
-Yellow Jackets-


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Eddins sworn in as judge
With his family, friends and a room full of attorneys and co-workers at his side, Gerald W. Eddins put his hand on the Bible and swore an oath to serve the people of Jefferson County as judge of County Court at Law No. 1. on Thursday, Nov. 29.
Jefferson County Judge Jeff Branick and 58th District Court Judge Bob Wortham spoke kindly of Eddins before his swearing in.
Both grew up with Eddins, they said, and spoke of his upbringing in Pear Ridge and how it will help the people of Jefferson County.
"Gerald's dad taught him from the beginning the importance of public service," Wortham said, noting Eddins worked as a volunteer firefighter for no pay at a young age.
"He even started driving the fire truck at 18. Can you imagine that?" Wortham said. "When I was 18, I don't think anybody would've given me a fire truck."
Judge Jeff Branick said that, although he was six years younger than Eddins, he looked up to that 18-year-old firefighter.
"Gerald and I were both born and raised in the bustling metropolis of Pear Ridge," Branick said.
Later in life, Branick joined Eddins at the Provost Umphrey Law Firm where Eddins was a partner and mentor to Branick, who was still working on his law degree.
"I could always count on being able to go to Gerald whenever I had questions about difficult legal concepts," Branick said. "He was very patient in a very encouraging way, assisting me in performing my duties in legal research."
After taking the oath of office, Eddins became momentarily emotional, saying he was humbled by those who precipitated his rise to judge.
"It is truly humbling and I'm truly honored by the universal support and acceptance I've received in this particular race," he said. "I received total support from the community. I received total support from the bar. I've very humbled by that."
Eddins said his time as judge of the County Court at Law No. 1 will be one of impartiality.
"I have been given a special trust, a chance to do right," he said. "And I'll live up to that."
Eddins is taking the seat vacated by Al Gerson, who retired after 27 years on the bench in October 2011. Tom Rugg of the Jefferson County District Attorney's Office occupied the seat in the interim.


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ELK GROVE VILLAGE, Ill., April 29 (UPI) -- Children most often obtain warts from a family member or another child in the classroom, rather than in a public setting such as a pool, Dutch researchers say.
Dr. Sjoerd C. Bruggink, Dr. Just A.H. Eekhof and colleagues of the Department of Public Health and Primary Care, Leiden University Medical Center in Leiden, Netherlands, said warts are caused by infection with human papillomavirus, which is transmitted by direct contact with contaminated skin or indirectly via objects that carry the virus.
To avoid transmitting the virus, public health recommendations are often issued to wear flip-flops in communal showers and to cover warts with waterproof bandages while swimming.
The study authors inspected the hands and feet of grade-school children in three schools in the Netherlands for the presence of warts, and again a year later.
Researchers asked their parents if other family members had warts, whether the child walked barefoot at home, went to public swimming pools, used public showers and practiced sports barefoot.
The research team also collected data on classmates and close friends who had warts.
The study, published in the journal Pediatrics, found children whose family members or classmates had warts were at higher risk of developing warts, but the use of public pools or showers was not a significant risk factor.
Bruggink and colleagues concluded health recommendations should shift toward reducing transmission among families and school classes, rather than in public settings. For example, covering warts at home would potentially prevent transmission more effectively than covering warts at the swimming pool.


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Court won't hear appeal from ex-Ill. governor
WASHINGTON (AP) — The Supreme Court won't hear an appeal from ex-Illinois Gov. George Ryan over his corruption conviction.
The justices on Tuesday turned away Ryan's appeal without comment.
The former governor wanted them to reconsider his conviction based on a 2010 decision saying honest service fraud requires bribery and kickbacks. Ryan said the jury instructions at his trial were wrong, and that it was never proven that he took bribes. The 7th U.S. Circuit Court of Appeals refused to overturn his conviction, and the high court refused to reconsider that decision.
A jury convicted Ryan in 2006 of racketeering, conspiracy, tax fraud and making false statements to the FBI. Ryan was released from prison earlier this year and is serving the rest of his sentence on home confinement.


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Inflammatory Bowel Disease
The University of Chicago Medicine is at the forefront of treatment and research into inflammatory bowel disease (IBD), with a multidisciplinary team of world-renowned experts who collaborate to bring patients the best possible treatment and the latest research and innovations into these complex conditions.
Inflammatory bowel disease is an umbrella term that includes Crohn's disease, ulcerative colitis (UC) and indeterminate colitis. These painful diseases involve an abnormal response by the immune system that damages the lining of the digestive system, causing inflammation and ulceration, severe abdominal pain, diarrhea, bloody stools, fatigue and/or weight loss.
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Because Crohn's disease and ulcerative colitis are complex and chronic conditions, it's important to work with physicians who understand their intricacies and have access to the latest therapies. The University of Chicago Medicine Inflammatory Bowel Disease Center is made up of a team of experts in clinical care and research, basic science and translational approaches – all working together to further knowledge of IBD causes and treatments. Our team approach ensures that every aspect of a patient's care involves specialists from different disciplines, all experienced in the management of Crohn's disease and ulcerative colitis. » Learn more about the IBD Center.