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Safety and Tolerability Study to Evaluate Lower Dose of GSK2248761 in Antiretroviral Treatment-Naive HIV-1 Infected Adults.
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00945282
Recruitment Status : Completed
First Posted : July 24, 2009
Last Update Posted : June 7, 2013
- Study Details
- Tabular View
- Results Submitted
- Disclaimer
- How to Read a Study Record
GSK has in-licensed a novel NNRTI-class candidate (GSK2248761, IDX12899) for the treatment of subjects with HIV-1 infection from Idenix Pharmaceuticals. Idenix Pharmaceuticals completed a proof-of-concept study evaluating GSK2248761 monotherapy over seven days in forty treatment-naïve subjects infected with HIV-1. GSK2248761 doses sequentially evaluated were 800 mg QD, 400 mg QD, 200 mg QD and 100mg QD.
This study will evaluate a lower dose, or doses, of GSK2248761 to better characterize the dose-response and concentration-response curves. The results from this study will be used to select doses for future clinical studies in HIV-1 infected subjects.
|Condition or disease
|Infection, Human Immunodeficiency Virus
|Drug: GSK2248761 Drug: Lopinavir/ritonavir Drug: HAART Drug: Placebo
|Phase 2
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|8 participants
|Intervention Model:
|Parallel Assignment
|Double (Participant, Investigator)
|Primary Purpose:
|Official Title:
|A Proof of Concept Study for GSK2248761 (An Extension of NV-05A-002: A Phase I/IIa Double-Blind Study to Evaluate the Safety and Tolerability, Antiretroviral Activity, Pharmacokinetics and Pharmacodynamics of IDX12899 in Antiretroviral Treatment-Naive HIV-1 Infected Subjects, Completed by Idenix)
|Study Start Date :
|October 2009
|Actual Primary Completion Date :
|December 2009
|Actual Study Completion Date :
|December 2009
Experimental: Cohort 1
In Cohort 1 subjects will receive either GSK2248761 30 mg or placebo once a day for 7 days. On Day 8 subjects will receive either Kaletra or HAART for 28 days. The doctor will choose the most appropriate medications for HAART.
Drug: GSK2248761
GSK2248761 30 mg capsule once a day for 7 days. GSK2248761 is an investigational (not approved by the FDA) HIV drug in the class of non-nucleoside reuptake inhibitor class.
Drug: Lopinavir/ritonavir
Lopinavir 400 mg and ritonovir 100 mg every 12 hours for 28 days. Lopinavir/ritonavir is approved by the FDA as an HIV medication in the protease inhibitor class. Kaletra is a trademark of Abbott Laboratories.
Other Name: Kaletra
Drug: HAART
Highly Active Antiretroviral therapy of the doctor's choice.
Drug: Placebo
Placebo is a capsule with no drug in it.
Experimental: Cohort 2
In Cohort 2 subjects will receive either GSK2248761 in the range of 10 mg - 20 mg or 40 mg - 90 mg or placebo once a day for 7 days. On Day 8 subjects will receive either Kaletra or HAART for 28 days. The doctor will choose the most appropriate medications for HAART. The dose for Cohort 2 will be determined following evaluation of results from Cohort 1. Cohort 2 may not be done.
Drug: Lopinavir/ritonavir
Lopinavir 400 mg and ritonovir 100 mg every 12 hours for 28 days. Lopinavir/ritonavir is approved by the FDA as an HIV medication in the protease inhibitor class. Kaletra is a trademark of Abbott Laboratories.
Other Name: Kaletra
Drug: HAART
Highly Active Antiretroviral therapy of the doctor's choice.
Drug: Placebo
Placebo is a capsule with no drug in it.
Drug: GSK2248761
GSK2248761 10 mg -20 mg or 40 mg - 90 mg once a day for 7 days. GSK2248761 is an investigational (not approved by the FDA) HIV drug in the class of non-nucleoside reuptake inhibitor class.
- Safety and tolerability parameters, including adverse event, clinical laboratory, electrocardiogram (EGC) and vital sign assesssments. [ Time Frame: 14 days ]
- Change from baseline through Day 8 in plasma HIV-1 RNA. [ Time Frame: 8 days ]
- GSK2248761 PK parameters following dose administration on Day 1 and Day 7. [ Time Frame: 8 days ]
- Change from baseline in reverse transcriptase sequences of HIV-1 at Day 8. [ Time Frame: 8 days ]
- Change from baseline CD4+ and CD8+ T-Lymphocyte cell count and percentages at Day 8. [ Time Frame: 8 days ]
- GSK2248761 PK parameters on Day 2 through Day 7. [ Time Frame: 8 days ]
- Day 1 and Day 7 PK data at different doses for the assessment of dose proportionality. [ Time Frame: 8 days ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|21 Years to 65 Years (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Male or Female, 21 to 65 years of age.
- Female of non-childbearing potential defined as: being post-menopausal, defined as 12 months of spontaneous amenorrhea and having a serum FSH level >40 MIU/ml at Screening OR have had a documented bilateral tubal ligation or hysterectomy of at least 6 months prior to study initiation, bilateral oophorectomy or bilateral tubal ligation.
- Plasma HIV-1 RNA value >= 5000 copies/mL.
- CD4+ count >= 200 cells/mm3.
- Is antiretroviral treatment-naïve and agrees not to start antiretroviral therapy prior to clinic check-in (Day-1).
- Subject agrees to start a standard HAART regimen on Day 8 of the study or Kaletra monotherapy for 28 days within 24 hours after the last dose of study medication.
- Capable of giving written informed consent, which includes being willing and able to comply with the requirements and restrictions listed in the consent form.
Exclusion Criteria:
- Subject is pregnant as determined by a positive urine/serum pregnancy test at Screening and Day -1.
- Lactating females.
- Male subjects of reproductive potential and unwilling to use double barrier method of contraception (e.g., condom plus spermicide) and continue to use an adequate method of birth control for at least 30 days after the last dose of the study drug.
- Has a positive screening Hepatitis B surface antigen, positive screening Hepatitis C virus (HCV) antibody and detectable HCV ribonucleic acid (RNA) on subsequent testing. If the Hepatitis C antibody is positive but the HCV RNA is undetectable, the subject may be included in the study.
- History of regular alcohol consumption within 6 months of Screening as defined as: an average weekly intake of >21 units for males or >14 units for females. One unit is equivalent to 8 g of alcohol: a half-pint (~240 ml) of beer, 1 glass (125 ml) of wine or 1 (25 ml) measure of spirits
- Has a positive pre-study drug screen. Drugs that will be screened for include amphetamines, barbiturates, cocaine and PCP.
- History of sensitivity to any of the study medications, or components thereof, or a history of drug or other allergy that, in the opinion of the Principal Investigator, contraindicates their participation. In addition, if heparin is used during PK sampling, subjects with a history of sensitivity to heparin or heparin-induced thrombocytopenia should not be enrolled.
Note: Study drugs include GSK2248761 placebo or the follow-up HAART or Kaletra therapy.
- Received an immunomodulating agent (e.g., interleukin-2) or immunotherapeutic vaccine within 30 days before Day -1.
- Requires a medication that is a known substrate, inhibitor and/or inducer of CYP3A4.
- Has received an investigational drug or participated in any other research trial within 30 days or 5 half-lives, or twice the duration of the biological effect of any drug (whichever is longer) prior to the first dosing day.
- Has ever had an AIDS-defining illness.
- Has a history of or has a currently active clinically important disease other than HIV-1 infection that, in the opinion of the Investigator, may put the subject at risk because of participation in this study (including renal and hepatic impairment, active infections including tuberculosis or opportunistic infection, malignancy and cardiac dysfunction).
- Has an intestinal malabsorption (e.g., structural defects, digestive failure, enzyme deficiencies, etc).
- Has a pre-existing NNRTI drug resistance based on genotyping at Screening.
- Where participation in the study would result in donation of blood or blood products in excess of 500mL within a 56 day period.
- Subject has any of the following laboratory parameters at Screening (a single repeat is allowed for eligibility determination): Hemoglobin <8.5 g/dL, Neutrophil count <1000 cells/mm3, Platelet count <100,000 cells/mm3, Serum creatinine > the upper limit of normal (ULN), AST or ALT <= 2.5 x ULN.
- Exclusion Criteria for Screening ECG (A single repeat is allowed for eligibility determination): Exclusion Criteria for Screening ECG: Heart rate: (males) <45 and >100 bpm (females) <50 and >100 bpm, QRS duration: >120 msec, QTc interval (Bazett): > 450 msec. Non-sustained (>= 3 consecutive beats) or sustained ventricular tachycardia. Sinus Pauses >2.5 seconds. 2nd degree (Type II) or higher AV block. Evidence of previous myocardial infarction (pathologic Q waves, S-T segment changes (except early repolarization)).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00945282
|Study Director:
|GSK Clinical Trials
|ViiV Healthcare
|Responsible Party:
|ViiV Healthcare
|ClinicalTrials.gov Identifier:
|NCT00945282 History of Changes
|Other Study ID Numbers:
|First Posted:
|July 24, 2009 Key Record Dates
|Last Update Posted:
|June 7, 2013
|Last Verified:
|March 2012
Keywords provided by ViiV Healthcare:
HIV Infections
treatment naive
Additional relevant MeSH terms:
Immunologic Deficiency Syndromes
Acquired Immunodeficiency Syndrome
HIV Infections
Immune System Diseases
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Slow Virus Diseases
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 Enzyme Inhibitors


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My daughter is 13+ months old and I'd like to stop pumping while at work. She eats solids well and we nurse whenever we are together (weekends and co-sleep at night).
However, I haven't been able to drop that last pumping session for 3 weeks now. I try to gradually push the time I pump later and later in the day, and by Friday it seems like I can be pump free (I get it down to 4:30 pm or so). Then I get to work on Monday after a weekend of unlimited nursing and I'm bursting with milk by 2pm. I've had lots of plugged ducts before, so I'm afraid to let my breasts get too engorged.
This has been going on for a few weeks now and I'm frustrated: I've been hoping to "hang up the horns" a month ago.
Any advice would be appreciated!

subset: commoncrawl


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Enjoy your favorite foods on occasion, but remember to keep portion size in mind. This recipe makes 8 servings.
Omit glass dish. Pour oil mixture over wings in resealable plastic bag. Seal bag; turn to evenly coat wings. Refrigerate 30 min. to marinate. Remove wings from marinade; discard bag and marinade. Grill wings as directed.
Serve as dippers with KRAFT Blue Cheese Dressing or KRAFT Classic Ranch Dressing.
Sprinkle with 1/2 cup toasted sesame seed before serving.
* Nutrition information is estimated based on the ingredients and cooking instructions as described in each recipe and is intended to be used for informational purposes only. Please note that nutrition details may vary based on methods of preparation, origin and freshness of ingredients used.


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This Week In Island History
The news of 10 and 15 years ago is from the Jamestown Press. The news of 100 years ago came from the collection of the Newport Historical Society.
100 years ago
From the Newport Journal, Dec. 6, 1912
A large buck was seen Friday in the west part of town, going south. Later it was seen near Beavertail on the Joseph Wharton farm.
The Ladies' Beneficial Society gave a clam chowder supper in memorial hall Tuesday evening. There was a good attendance.
75 years ago
From the Newport Daily News, Dec. 3, 1937
The committee of the Jamestown Post American Legion has made arrangements for the writing of competitive essays on a patriotic subject by the school children in their homes. Prizes will be given.
From the Newport Daily News, Dec. 6, 1937
Captain and Mrs. Clarence H. King quietly observed their 42nd wedding anniversary during the past week at their home on Narragansett Avenue. Captain and Mrs. King were married in 1895 at the home of Captain Charles Arnold in Saunderstown.
Mr. and Mrs. William A. Gosford, who have been occupying the Harry H. Horgan cottage on Union Street, have purchased the Gardner Inn Annex on Union Street. From the Newport Daily News,
Dec. 7, 1937
The Jamestown Rod and Gun Club held its first meeting as an organization chartered by the state of Rhode Island at Town Hall recently. The club proposes to affi liate with the State Federation of Gun Clubs and is starting work on a trap and skeet field for use by members next year.
50 years ago From the Newport Daily News,
Dec. 1, 1962
A group of young men in Jamestown will meet Tuesday to take the preliminary steps in organizing a junior chamber of commerce. From the Newport Daily News,
Dec. 5, 1962
Captain Kidd's 4-H clubs in Jamestown have organized a new horse group, with Charles Young as leader. Two field trips have already been taken by the group, which will elect officers at this week's meeting. From the Newport Daily News,
Dec. 6, 1962
The Jamestown Ferry lost $228,240 during the fiscal year that ended last June 30. Its loss for the current fiscal year is estimated at $110,000, but its projected loss for the fiscal year beginning next July 1 zooms again to $192,723.
25 years ago From the Newport Daily News,
Dec. 2, 1987
The Town Council is making a last ditch effort to change the proposed Route 138 bridge-connector design. A resolution sent out this week reflects the same concerns the council expressed last summer. Those concerns brought the road process to a grinding halt when the Federal Highway Administration ordered the state Department of Transportation to address them. From the Newport Daily News,
Dec. 3, 1987
Gov. DiPrete announced the awarding of $63,500 to the town of Jamestown and to two state agencies to combat the widespread use of alcohol and drugs. From the Newport Daily News,
Dec. 9, 1987
The New England Coatings Association intends to restore the inside of the Beavertail Lighthouse as part of a national contest. The "Picture it Painted" contest, sponsored by the National Coatings Association Community Service program, judges restoration of historical sites from each area of the country.
15 years ago
From the Jamestown Press,
Dec. 4, 1997
It was approaching midnight when the Zoning Board of Review unanimously approved a joint request by East Passage Sailmakers and the Jamestown Recreation Department to lease the second floor of the town-owned country club to these two tenants. The sailmakers want to occupy about 60 percent of the country club's second floor.
The Zoning Board of Review has voted to uphold a permit issued to the Conanicut Yacht Club Sept. 16 for the construction of two coin-operated paddle tennis courts for its members.
10 years ago
From the Jamestown Press,
Dec. 5, 2002
Town Tree Warden David Nickerson has presented a detailed report to the Town Council on village trees in response to the council's request for an evaluation of trees on Narragansett Avenue. The request was keyed especially to concerns about roots lifting sections of sidewalks in the village district, and discussions of designs for sidewalk renovations have been started.


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US President Barack Obama announces his choice of Jack Lew (R) as the next Treasury Secretary on January 10, 2013
President Barack Obama picked Jack Lew as his new Treasury secretary Thursday and called on the Senate to confirm him as quickly as possible, so he can press on with the work of reviving the economy.
Lew, Obama's current chief of staff, is slated to take over from Tim Geithner, who stood by Obama's side at the darkest moments of the crisis that was hammering American jobs and prosperity when he took office in 2009.
"I cannot think of a better person to continue Tim's work at Treasury than Jack Lew," Obama said, in a White House event rounding out his nominations for the top cabinet jobs in his second term which begins on January 20.
"Jack knows that every number on a page, every dollar we budget, every decision we make, has to be an expression of who we wish to be as a nation.
"So, I hope the Senate will confirm him as quickly as possible," Obama said, though almost as soon as he spoke, his Republican opponents ratcheted up a campaign of opposition against his new nominee.
Lew, 57, is a classic Washington insider, with multiple tours of duty across the government, including two as budget director, for former president Bill Clinton and Obama, and a spell as deputy secretary of state.
His selection symbolically hit the start button on a new showdown between Obama and Republicans on Capitol Hill, just over a week after the end of the "fiscal cliff" tax and spending tussle.
Lew will be charged with the job of persuading Republican lawmakers to raise the US government's debt ceiling from its current $16 trillion level to stave off the prospect of a disastrous government default.
He will also be in charge of another row over billions of dollars in automatic government spending cuts now due at the end of February after being delayed for two months in the fiscal cliff compromise.
Lew, who is widely respected in Washington but has taken on baggage after years in the partisan stew, will still likely have an easier confirmation process than other second term nominees like Chuck Hagel, Obama's pick to head the Pentagon.
"Jack has my complete trust ... in the words of one former senator, having Lew on your team is the equivalent as a coach of having the luxury of putting somebody at almost every position and knowing he will do well," Obama said.
Obama emphasized the success that Lew had in turning deficits into budget surpluses during the Clinton administration, but Republicans immediately focused on the more challenging time he had as this president's budget director.
"Under Jack Lew's leadership at the Office of Management and Budget, we saw trillion dollar deficits and no serious attempt to rein in spending," said Republican Senator John Cornyn.
"As president Obama's chief of staff, we've seen on-going dilatory tactics as the nation stares down one fiscal crisis after another."
Fellow Republican Jeff Sessions also hit out at Lew's record.
"I believe this man has been the architect of the Obama budget policy. I believe it's very fundamentally wrong and I do not believe he has been honest with the American people about it," Sessions said.
Given the advantage Democrats hold in the Senate however -- with 55 of the 100 seats -- many Washington observers expect Lew to be confirmed after a period of political bloodletting.
Obama also paid a glowing tribute to Geithner, who had a rocky start at Treasury, but has since emerged as one of the more high-profile people to hold the job in recent years.
"When the history books are written, Tim Geithner's going to go down as one of our finest secretaries of the Treasury," Obama said.
Geithner's sharp intellect is disguised by a humble manner and he is personally close to Obama, who liked his low maintenance style.
"There's (an) unofficial thing over at Treasury -- no peacocks, no jerks, no whiners. That would be a good thing for all of Washington," Obama said.


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Wright Elementary School's Site-Based Decision-Making Council has named Bethany Groves the new principal for the school, the school district announced.
Groves has five years of experience in administration, most recently in Jacksonville, Fla., at Hickory Creek Elementary.
A 1982 graduate of Shelby County High School, Groves has degrees from Ohio University and Northern Kentucky University and her Phase 1 doctoral work from Indiana University/Purdue University Indianapolis.
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It was certainly a big year for Amar'e Stoudemire and wife Alexis, but 2013 may just prove to be their slam dunk.
The couple, who were engaged in Paris in June and tied the knot on Dec. 12 (12-12-12) on their N.Y.C. apartment roof deck, reveal that they're expecting their fourth child together late this spring.
"We're blessed that we were able to extend our family," the New York Knicks forward, 30, tells PEOPLE exclusively.
"We're both huge on having a nice size family. It was something we've been talking about for a while. It happened naturally and at the right time so it all worked out."
"It was just perfect timing," adds Alexis, 29, who says she's had some morning sickness but overall, "can't complain!"
The duo, who already have three children together — Ar'e, 7, Amar'e Jr., 6, and Assata, 4 — say everyone is thrilled for the impending arrival.
"They're very, very excited," says Alexis. "They just keep guessing if it's a boy or a girl." And it won't be long before the sex is revealed, "I can't wait to know what it is," says Amar'e.
"As soon as Amar'e walks into the door those kids are all over him," says Alexis with a laugh. "He's like a big kid. He's a great dad."
And as for mom, who mans the house while Amar'e is on the road, "she does it all," says Amar'e. "She does such a phenomenal job with the kids. I'm just here to be the big teddy bear."
After marrying in December, the couple will hold another wedding celebration this summer. "We're planning a big, extravagant Cinderella wedding for Alexis!" says Amar'e.
"It was beautiful to have a private ceremony with close family and friends," says the star of their December nuptials. "I planned it; I wanted to have something that was more spiritual where we could really understand what being married means. It was a great way to end 2012."
And, says Alexis, "We included the children in our ceremony as well. That was very important to us. It's something they'll always remember."
Amar'e will be honoring his brother Hazel, who passed away last year in a car accident, this weekend by inviting 30 kids from his Florida hometown to the upcoming Orlando Magic vs Knicks game. "I just want them to get away for a little bit and enjoy."
Looking forward to the new year and a new baby, "Hopefully we'll bring home a championship and we'll celebrate with a wedding after that!" adds Amar'e.
— Jennifer Garcia


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Value Line is regarded as the best independent research available. More than just recommendations, Value Line provides the rationale behind its picks for greater understanding.
Among the many features found in each week's edition of Value Line's Selection & Opinion service is a list of the seven best and worst performing industries over the past six weeks. These rankings can be found on the inside back cover of Selection & Opinion. The roughly 1,700 stocks in the Value Line universe are currently divided among about 100 industries. Notably, for the purposes of calculating these results, the performance of each stock is equally weighted to the others in its industry (i.e., irrespective of market capitalization).
The latest six-week period covered in our latest Industry Price Performance rankings was an unexceptional stretch for equities. The bull market continued to push ahead to new heights in November, but stock prices faltered in early December, leaving most of the leading market benchmarks showing modest gains for the period between October 29th and December 10th. From an industry perspective, winners narrowly edged losers over the past six weeks, and a fairly pedestrian advance of 5.1% was good enough to qualify for a spot in our top seven. The Shoe Industry rose 9.4% to take home the top spot. Other groups in demand among investors were Life Insurance (8.6%), Securities Brokerage (7.8%), Retail Automotive (7.2%), Steel (6.2%), Computers & Peripherals (5.7%), and Aerospace/Defense (5.1%).
In looking for investment ideas among these seven industries, we are taking a closer look this week at Aerospace/Defense stocks. The group's strong performance of late is nothing new. Indeed, 2013 as a whole has been a very good year for investors in this space. Year-to-date, the median total return for this group exceeds 50%.
As is frequently the case, one of the sector's more volatile, small capitalization stocks has rung up some of the biggest gains this year. Shares of Astronics (ATRO), a designer and manufacturer of control, lighting, and power systems, have more than doubled in price so far in 2013. The New York-based company is certainly having a strong year, with sales and earnings on track to rise 26% and 21%, respectively. Aside from its strong operating performance, the company's appeal as a potential acquisition candidate by one of the larger players may well be contributing to its increased popularity with investors. That said, this equity is now trading at a lofty valuation (nearly 30-times earnings) that figures to be difficult to sustain over an extended period. In view of this, the stock's primary appeal at the moment is likely to be with more speculative investors anticipating further developments on the mergers and acquisition front.
Elsewhere, the industry's biggest names have hardly been shortchanging shareholders. Most notably, Boeing Company (BA) stock is up nearly 80% this year and now has a market capitalization of roughly $100 billion, more than double that of any other aerospace/defense stock. As with ATRO, though, we have concerns that the valuation on BA shares may have gotten ahead of itself. Granted, the operating performance of the Chicago-based jet manufacturer has been more than commendable of late. Most recently, September-quarter earnings rose 12% year over year, on an 11% increase in revenues. For the year, we look for share net to reach $5.80, up 14% from 2012, and we think per-share profits can continue to climb at a low double-digit clip in the upcoming year and out to 2016-2018. This is based, in part, on our view that rising rates of passenger air travel will push domestic and foreign airlines to replace their aging fleets with new aircraft.
Even with these generally favorable prospects, investors should proceed cautiously here, given the limited share-price appreciation potential we see for BA stock in the 3 to 5 years ahead. In particular, we have concerns that this equity's P/E multiple, which now exceeds 20-times 12-month earnings, will retreat back into the mid-teens range where these shares have typically traded in recent years.
That said, investors focusing on price appreciation potential to 2016-2018 don't have to completely swear off aerospace/defense stocks for the time being. For instance, shares of Spirit AeroSystems (SPR) have been on a tear this year (up about 90%) and still appear to offer worthwhile upside for the long term. Notably, the designer and manufacturer of aerostructures, such as fuselage, propulsion, and wing systems, has close ties to Boeing, generating more than 80% of its revenues from the aircraft giant. In fact, it operated under the Boeing umbrella before being sold in 2005 to Onyx Corp., the latter of which remains its largest shareholder.
Spirit Aerosystems is wrapping up a rather eventful year, in which it has revamped its management team (bringing in a new CEO and CFO) and announced plans to sell two plants in Oklahoma. Meanwhile, from an earnings perspective, the company will probably be glad to put 2013 behind it. Share net is likely to come in at $0.30, though profits would have been much higher were it not for second-quarter charges related to Gulfstream business jet programs. In the absence of such a setback, earnings should jump to $2.50 in 2014, a record high. Favorable fundamentals in the commercial aerospace industry ought to continue providing a backing wind beyond that, with annual profits likely reaching $3.50 a share or more in the 2016-2018 timeframe.
Given this positive long-term outlook and the current reasonable valuation (about 13-times 12-month earnings), investors here stand a good chance to be rewarded with above-average price appreciation in the 3 to 5 years ahead. On the downside, the stock can be rather volatile (Price Stability: 25 out of 100) and doesn't pay a dividend. These attributes will likely limit its appeal with more-conservative investors.
At the time of this article's writing, the author did not have positions in any of the companies mentioned.


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This letter is for Catherine Spencer. I don't believe that we have met face to face but I believe I know your heart from years' worth of letters to the editor that you have sent in. When I start to read a letter and the first feelings I get are anger and hatred, I look to the signature line and sure enough - it's from you. Most of the time I ignore your letters; other times I read them and think, " Wow. How can one woman be so mad all of the time?" Surely you must have high blood pressure. Are you so lonely, unloved or maybe just disgusted with your own life that you take it out on everyone else in a free "letter to the editor"? Bless your heart. I can't imagine such a life.
We all live a life of free will, Catherine. If you are that unhappy with everything around you in your community and your country then maybe you should leave and go somewhere else where everyone else agrees with you. Really - is there such a place? Or maybe head to Washington to press your points. Ranting and raving at your friends and neighbors in Cortez isn't going to solve anything. Of course, you probably just like the attention you stir up.
Having no idea of your religious background (if indeed you have one) I won't wish you a Merry Christmas or a Happy Hanukkah. I do however, wish you peace. Maybe instead of expending all that hatred and anger in your life, you could re-direct that energy to do something good in this world. You would probably breathe easier for it. And I think you might even find some happiness along the way.
Debie Schmitt
Via email


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Pennsylvania officials have expanded its quarantine of deer farms after its investigation into any that may have had contact or have had contact with a confirmed case of chronic wasting disease.
Twelve farms now are listed under the quarantine, the Pennsylvania Department of Agriculture announced Friday. The department is seeking any and all farms that have had any contact with the CWD-infected deer, according to this report in The Patriot-News.
The newspaper reported that as state officials from the U.S. Department of Agriculture Wildlife Services division were killing deer in an enclosure where an infected deer died, one doe broke through the fence and escaped. Officials are searching for that deer although the area surrounding the 1.5-acre enclosure farm is primarily wooded suburbia.
For the full story from Marcus Schneck and The Patriot-News, go here.
Schneck also has an updated story from hunters' check-in stations.
Ban on feeding?
Pennsylvania already prohibits feeding bears and elk but has no such restriction about whitetails.
David Wolfgang, a veterinarian in the Penn State University College of Agricultural Sciences, believes that should change. Wolfgang is an extension service veterinarian and field studies director in veterinary and biomedical sciences.
"The commissioners should follow the advice they have been given by a variety of deer experts, including the agency's own wildlife veterinarian, and stop the feeding of deer," Wolfgang said in this story posted on the Penn State University news site. "When we feed deer, we congregate the animals, and that dramatically increases the potential that diseases, such as chronic wasting disease (CWD), will spread among them. There is no disagreement about that.
"It would be wise for them to go ahead now and do the right thing for the wildlife of Pennsylvania," he said.
Wolfgang represents Penn State on the state's Chronic Wasting Disease Task Force, which also includes representatives from the Game Commission and the state departments of agriculture and health. He is most concerned about another practice that game commissioners could stop: the placing of salt or mineral blocks for deer.
"Where salt licks or mineral blocks are put out, obviously deer congregate, and that is bad enough," Wolfgang explained. "But what's worse is that after being exposed to rain and snow, the minerals leach into the surrounding ground, and then for years deer bite and chew at the dirt.
"If a CWD-infected deer would visit the mineral lick, prions that spread the disease likely would get into the soil from its urine and feces. The last thing we want is for deer to be eating dirt in areas where deer have congregated."
Wolfgang, who is a past president of the Pennsylvania Veterinary Medical Association, also is worried about the wide use of deer urine by bowhunters as a lure or attractant. He suggested that game commissioners consider banning that practice in Pennsylvania, as well.
Doe urine, collected at deer farms across the country, is packaged commercially and sold to help archers draw into arrow-shooting range the mature bucks they seek.
"Some scientists now wonder if the wide distribution of doe urine might be partly responsible for the spread of CWD from the West to the East," he said.
"Doe urine from deer in other states should not be introduced into Pennsylvania soils. Even the small risk that the purchased doe urine might contain CWD-causing prions should discourage responsible hunters from using it."
Read the entire PSU press release here.
What do you think about Wolfgang's assertions? Feeding and salt or mineral blocks should be prohibited? What about deer urine?
Let us know your comments below.


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28 U.S. Code § 2242 - Application
Application for a writ of habeas corpus shall be in writing signed and verified by the person for whose relief it is intended or by someone acting in his behalf.
It shall allege the facts concerning the applicant's commitment or detention, the name of the person who has custody over him and by virtue of what claim or authority, if known.
It may be amended or supplemented as provided in the rules of procedure applicable to civil actions.
If addressed to the Supreme Court, a justice thereof or a circuit judge it shall state the reasons for not making application to the district court of the district in which the applicant is held.
Based on title 28, U.S.C., 1940 ed., § 454 (R.S. § 754).
Words "or by someone acting in his behalf" were added. This follows the actual practice of the courts, as set forth in United States ex rel. Funaro v. Watchorn, C.C. 1908, 164 F. 152; Collins v. Traeger, C.C.A. 1928, 27 F.2d 842, and cases cited.
The third paragraph is new. It was added to conform to existing practice as approved by judicial decisions. See Dorsey v. Gill (App.D.C.) 148 F.2d 857, 865, 866. See also Holiday v. Johnston, 61 S.Ct. 1015, 313 U.S. 342, 85 L.Ed. 1392.
Changes were made in phraseology.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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Gateway to the Marvels of Luxor
While Safaga has its share of charms, including renowned healing properties of the mineral rich waters of the Red Sea, nearby Luxor is where the main attractions lie. Known as "the world's greatest open air museum", the monuments, temples, and tombs found in Luxor are amongst the most impressive in the world.
Nestled in the heart of the city, the Luxor Temple is a great place to start your ancient journey of discovery. Nod to the two massive seated statues of the most celebrated and powerful pharaoh, Ramses II, as you pass en route to the chapel of Alexander the Great. Then, continue on your way to Egypt's second most visited tourist site, Karnak, the largest religious site in the world. Marvel at the sheer enormity of the Temple of Amun, count all 134 columns in Hypostyle Hall, and then explore the array of smaller temples, sanctuaries, and shrines.
But wait, there's more! The Valley of the Kings is just a quick jaunt across the Nile. Here, you can see more than 63 tombs of Egyptian pharaohs and nobles, including the infamous final resting place of King Tutankhamen. End your day onboard a felucca (a traditional wooden sailboat) and sail back to the east bank as the sun starts to set over this mysterious land.
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Luxor Temple
Luxor Temple
Located on the eastern bank of the Nile River, the temple is one of the best examples of ancient Pharaonic architecture. Highlights found within the temple include the 1st Pylon, standing over 78 feet tall, and the colossal statues of Ramses II.
Temples Of Karnak
Temples Of Karnak
Step back in time and enjoy a leisurely walk through the three distinct areas of the temple site. Built over a period of 1,500 years, this was the most important temple in all of Egypt during the height of Theban power.
Luxor And Valley Of The Kings
Luxor And Valley Of The Kings
In Luxor, visit the greatest place of worship in history, the breathtaking Karnak Temple with its unique Hypostyle hall, sacred lake, and avenue of the Sphinxes. Enjoy a sumptuous buffet lunch in a deluxe 5-star hotel before visiting the Valley of the Kings.About Shore Excursions +Book Now +
Featured Safaga (Luxor), Egypt
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Safaga (Luxor), Egypt At a glance
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- 3.67
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- 1.09


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MANAMA, Bahrain (AP) — Bahrain's leaders pushed back against criticism by a leading rights group Wednesday that the Gulf state has failed to follow through with promised political and security reforms in the wake of the kingdom's anti-government uprising.
Authorities cited a series of measures taken since an independent report on the crisis came out last November, including giving more oversight to parliament.
Amnesty International says any progress has been overshadowed by harsh steps recently in attempts to quell the 21-month-old protests, including a ban on demonstrations and stripping 31 activists of citizenship.
"Bahrain is facing a stark choice between the rule of law or sliding into a downward spiral of repression and instability," Amnesty said in a report, issued on the anniversary of the independent fact-finding inquiry into Bahrain's unrest.
The inquiry, led by Egyptian-born legal scholar Mahmoud Cherif Bassiouni, called for sweeping overhauls in Bahrain's political system and investigations into alleged abuses by security forces after protests began in February 2011.
More than 55 people have been killed in clashes between Bahraini authorities and Shiite-led protesters demanding a greater political voice in the Sunni-ruled kingdom.
Amnesty claims that Bahrain's rulers have made no serious effort to open the political system and have turned to hard-line measures to try to crush and intimidate the Shiite opposition. Last month, Bahrain imposed a blanket ban on political protests and later stripped 31 activists of their citizenship because of alleged protest links.
Both moves brought criticism from Washington, which has critical strategic ties with Bahrain as host of the U.S. Navy's 5th Fleet. The base is one of the Pentagon's major counterbalances to Iran's expanding military presence in the Gulf.
On Tuesday, a senior U.S. official expressed worries that Bahrain's "society is moving apart" and could offer Iran new footholds in the tiny island nation. There is no direct evidence that Shiite power Iran supports Bahrain's protesters, but the U.S. and its Gulf Arab allies are wary of any chance of Iranian inroads in the region. The official spoke on condition of anonymity as part of a background briefing for journalists.
Amnesty said continued arrests and crackdowns by Bahraini authorities have made "a mockery of the reform process."
"Indeed, it has become evident that the authorities in Bahrain do not have the will to take the steps necessary to reform. Protestations to the contrary only underscore the gap between their rhetoric and reality," said Hassiba Hadj Sahraoui, Amnesty's deputy Middle East and North Africa director.
Hours after the Amnesty statement, a court in Bahrain sentenced 23 medical professionals to three-month jail terms on charges that included supporting protesters during the early weeks of the uprising last year. The sentences were suspended in lieu of fines, lawyers said. The cases against five other medics were dropped.
The U.S.-based Physicians for Human Rights group expressed dismay at the decision.
"We are disappointed, though not surprised, that the Bahraini regime once again has decided to punish health professionals merely for expressing their right to peaceful assembly," said Richard Sollom, deputy director of PHR, adding that Bahrain "should focus on prosecuting the people responsible for torturing many of those who were arrested and detained."
Bahraini authorities blame protesters for stepping up the level of violence, including frequent attacks by homemade firebombs and a series of blasts earlier this month that killed two expatriate workers from India and Bangladesh.
Bahrain's rulers also say they have made serious concessions, such as giving more oversight to parliament and investigating claims of abuse by security forces. Shiite leaders say that falls far short of demands for a role in high-level policymaking.
A Bahrain government progress report on the commission's recommendations says "ongoing reforms" are part of efforts to "combat violence and terrorism which has adversely affected the lives, security and wellbeing of citizens and residents."


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Main Site - :: Why Won't God Heal Amputees? ::
0 Members and 1 Guest are viewing this topic.
"I'm doing science and I'm still alive."--J.C.
You believe evolution and there is no evidence for that. Where is the fossil record of a half man half ape. I've only ever heard about it in reading.
You should have known from the start she was going to make waves.
Maggie is opinionated; it says that right in her username. You should have known from the start she was going to make waves.
Your suspicions are probably better placed in the posts that got me banned last time than what someone from IGI did or failed to do.
She was very insulting too and made lots of false accusations.
Anyway, once in a while we see this conflict between the two forums and don't fully understand why it actually happens - we know what has happened and the reasons for it, yet see little point in it - at the very least I don't see much point to it (I can't speak on behalf of everybody else).
Unfortunately, we get some bad rep from theists we've ended up banning (and probably atheists we've banned too)...but then you kinda expect that. Somebody who's banned isn't going to go around telling people how great the forum is.
I was a moderator when you were banned (Moderator B01) and I remember the thread in the admin section and the decision wasn't sudden.
IMO the best forums I've visited work by that mechanic, because it allows a moderator to deal with disruptive situation that's not technically against the rules if you were to use any legal interpretation. It doesn't suit everybody or every forum's goals and that's fine, you can't please everyone.
So welcome back to the forums. I hope it works out for you and hope to see all of us getting along.
Like I said, Maggie is Maggie.
And then, of course, there are the many individual stories of members who felt mistreated over the years not related to that early drama. You see, when anti-WWGHA sentiment shows up on IGI, very rarely is it from someone who hasn't been here. Nearly every single post is from someone who tried this forum and came away with bad memories. Now, you can write off some of the above as exaggeration or hearsay, and I fully admit that I was not a first-hand witness to most of it, but my point is that this isn't just one or two pissed off parties poisoning the well. There are an awful lot of people who have had an awful lot of problems with this site, which is why it baffles me that you would make a comment like that.
Not baffled that you personally don't see a point in it, of course. Moreso baffled in the overall message of what you're saying. Imagine someone telling a black man, "Anyway, once in a while we see this conflict between the two races and don't fully understand why it actually happens - we know what has happened and the reasons for it, yet see little point in it - at the very least I don't see much point to it (I can't speak on behalf of everybody else)." The point is that it's easy for one side to slight a group of people and then say, "My bad!" and expect them to get over it. It's a lot harder for the other side to ever trust them again, especially when the offending parties are still in charge.
Well, that's all well and good. In the future I will keep in mind that when I see a thread that specifically says, "You can do x as long as you don't do y," it means that doing x while avoiding y is lawyering. That should steer us clear of any problems, right?
Interesting you'd complain so much about our behaviour here and how the mods operate, but a theist like Maggie? She shows some pretty damn detestable behaviour, but she's just Maggie.
You wouldn't believe how many theists come here and don't show our forum rules the right amount of respect and often don't allow themselves to be accountable for the things they say.
No we're the intolerant atheists who hate theists and aren't interested in an honest discussion with them but are intent on banning them.
I have been on the receiving end of this forum's style.
But the arguments between IGI and WWGHA seem to be petty at times.
So essentially as a forum we're prejudiced towards theists?
it doesn't mean I'm gonna hold you to a different standard to anybody else.
Religions need books because they don't have gods.
Of course I would. I was on WWGHA for four years before I was banned. You probably still get a lot of drive-by preaching. Frankly, the website is set up to attract these people: it's going to rile up the most sensitive and angry of them, and then link them to the forum
I can only speak to my own experience. This site has always been hostile to theists, but it was around 2010 that I noticed the ban hammer was especially hammery.
So have I. It never bothered me much in the past, except for that period in 2010 where it seemed like the moderators were using their powers to keep it from being a fair fight.
Yes, definitely. It's been that way since WWGHA1
I always say what I mean. But sometimes I'm a sarcastic prick whose tone can't be properly communicated via text.
The famous pipe. How people reproached me for it! And yet, could you stuff my pipe? No, it's just a representation, is it not? So if I had written on my picture "This is a pipe," I'd have been lying! - Magritte
This person does not understand language. Does she have an email? I can set her straight, if you want.
The text exists within the context being represented. As such, from within its own reference frame, the text is false: The pipe could indeed be stuffed, smoked, broken. This could all be done to/with the image, and the image would represent stuffing, smoking, or breaking of a pipe. Text within the same image should accurately refer to the reality it shares with the pipe.
That quote is from the painter himself. He died before email was invented.


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Date: April 10, 2008
"Silent No More" Leaders
Urge Gov. Henry to Sign Pro-Life Bill
"From permitting women to see ultrasounds of their babies prior to
abortion to allowing health care workers to opt out of participating in
procedures that violate their consciences, this bill would protect the
rights of many people," said Georgette Forney, co-founder of SNMAC.
"It's rare that so much good could come from one piece of legislation."
The bill is particularly important to women who may be
pressured into abortion," adds Janet Morana, another co-founder of SNMAC.
"It would require that abortion facilities post a sign reminding women that it
is against the law for anyone, even a relative, to force them to terminate their
child's life. Governor Henry has a wonderful opportunity to protect
women's rights by signing this measure."
Since the launching of the Silent No More Awareness
Campaign in 2003, 2,326 women and men have shared their testimonies publicly at
over 200 gatherings in 44 states and six countries where more than 15,000
spectators have heard the truth about abortion's negative aftereffects.
More than 4,100 people are registered to be Silent No More. Raising
awareness about the hurtful aftermath of abortion and the help that is available
to cope with the pain are two of the Campaign's goals.
The Silent No More Awareness Campaign is a joint project
of Anglicans for Life and Priests for Life. For more information, please


text:
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Started this discussion. Last reply by Leah Sloan Sep 17, 2010. 3 Replies 0 Likes
**UPDATE** Looks like I should have left the URL for my blog. My profile had a typo in it. I am at…Continue
Tags: authors, challenges, parenting, books, adventures
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ONTOLOGY-BASED SEMANTIC INTEGRATION OF HETEROGENEOUS INFORMATION SOURCES by Sangsoo Sung A Dissertation Presented to the FACULTY OF THE GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (COMPUTER SCIENCE) May 2008 Copyright 2008 Sangsoo Sung
Object Description
|Ontology-based semantic integration of heterogeneous information
|Sung, Sangsoo
|Author email
|Doctor of Philosophy
|Document type
|Degree program
|Computer Science
|Viterbi School of Engineering
|Date defended/completed
|Date submitted
|Restricted until
|Restricted until 25 Jan. 2010.
|Date published
|Advisor (committee chair)
|McLeod, Dennis
|Advisor (committee member)
Horowitz, Ellis
Pryor, Lawrence
|The main goal of this research is to improve interoperability between different information sources. Since ontologies, collections of concepts and their interrelationships, have become a synonym for the solution to many problems resulting from computers' inability to understand natural language, they can capture the semantics of diverse representations in heterogeneous information sources. Thus, ontologies can facilitate the identification of semantic matching between the different representations. Therefore, this dissertation studies the role of ontologies in semantic matching structured data and a method of building ontologies for the semantic matching.; One of the critical problems in the federation of information sources is that similar domains have been expressed in different manners. To address this problem, this dissertation presents an ontology-based federation of heterogeneous information sources. We define a simple yet powerful representation model for structuring ontology which can extract canonical representation from a broad range of meta data models, including relational databases, XML, RDF, OWL, and DAML+OIL.; The second major problem in the federation is that similar domains also have been expressed in diverse terminologies by domain experts who typically have their own interpretations of the domain. To tackle this problem, we incorporate ontologies to identify matches among different terminologies. Since ontologies play a key role in knowledge management by providing solutions to many problems resulting from computers' inability to understand natural language, they can facilitate the identification of semantic matching between the different representations. The basic idea in computing the semantic similarity is that similar concepts share a more specific common parent.; As many thousands of articles are published daily on the Web, neologisms or domain specific terms appear as time passes. Thus, the third major problem in the federation is that the employment of out-of-date ontologies may decrease the accuracy of our matching framework. Also, the ontology learning process where traditional clustering algorithms are involved tends to be slow and computationally expensive when the dataset is as large as the Web. Therefore, it is essential to maintain ontologies to reflect up-to-date knowledge. To address this problem, we present an efficient concept clustering technique for ontology learning that reduces the number of required pairwise term similarity computations without a loss of quality.; This study makes three major contributions. The first contribution is a solution architecture that resolves conflicts in the semantics of existing information sources. The second major contribution of the research is a solution to automatically create semantic mappings. The another important contribution of this dissertation is a solution architecture that provides a well-founded, rapid ontology learning framework based on the reduction of the use of the expensive measure by pre-clustering a large dataset. Our approach can be coupled with any type of federating, matching, clustering methods and can be utilized for making algorithms scalable with respect to the millions of information sources and documents. Therefore, this dissertation has contributed to both understanding the integrating problem on diverse information sources and developing matching framework using ontologies.
|ontology management; ontology learning
|Part of collection
|University of Southern California dissertations and theses
|Publisher (of the original version)
|University of Southern California
|Place of publication (of the original version)
|Los Angeles, California
|Publisher (of the digital version)
|University of Southern California. Libraries
|Legacy record ID
|Contributing entity
|University of Southern California
|Sung, Sangsoo
|Repository name
|Libraries, University of Southern California
|Repository address
|Los Angeles, California
|Repository email
|Archival file
|Page 1
|Contributing entity
|University of Southern California
|Repository email
|Full text
|ONTOLOGY-BASED SEMANTIC INTEGRATION OF HETEROGENEOUS INFORMATION SOURCES by Sangsoo Sung A Dissertation Presented to the FACULTY OF THE GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (COMPUTER SCIENCE) May 2008 Copyright 2008 Sangsoo Sung


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EDISON, N.J. (AP) — In many ways, TiVo's digital video recorders have become redundant as cable and satellite TV companies offer their own DVR services. Yet the company that pioneered DVRs 14 years ago keeps churning out new products.
Avid television viewers will appreciate that. The fifth-generation TiVos, called Roamio, continue the company's tradition of giving you much more than you can get from your cable or satellite company. That includes the ability to watch recorded shows when you're away from home, starting this fall.
But you'll also pay much more for the experience — $400 for the mid-range model, plus a monthly service fee of $15. By contrast, you can often get DVR service through your TV provider for a comparable monthly fee, with no extra equipment to buy.
If you don't watch a lot of television, Roamio isn't for you. It would be like going to a five-star restaurant when all you want is bread. But Roamio is a worthwhile investment if you have hundreds of television channels and Internet video services and can't figure out where to start.
Like other DVRs, you can pause live television to answer the phone or the door. You can rewind live sporting events and create your own replays. Get home 15 minutes late? You can start watching a show from the beginning as it's still being recorded.
Where TiVo has excelled is in helping you find programs to record. You can create wish lists of favorite actors and have TiVo automatically record movies or talk shows they appear in. You can also do the same with keywords, such as "national park" or "dolphins." You can even have TiVo offer suggestions based on your past viewing, though I have found its picks dubious at times.
TiVos also integrate TV shows and movies from Internet video services such as Netflix Inc., Amazon.com Inc. and Hulu. When you search for "Breaking Bad," for instance, you get a list of episodes the AMC channel is showing over the next two weeks plus all the episodes available on Netflix or Amazon. To watch through TiVo, you still have to get a Netflix subscription or buy individual episodes through Amazon, but it's good to know you can get past episodes there. You can also search for related video on YouTube and see what other shows cast members from "Breaking Bad" are in.
The new TiVo has all that, plus suggestions on what to watch now, rather than just what to record in the future. It's based partly on what other TiVo users are watching at the moment or have watched in that time slot in the past.
Roamio also lets you customize the on-screen television listings. If you're in the mood for a movie, you can have TiVo show you just the movies when you scroll through the listings. You can customize that further and scroll through just comedies or documentaries. Instead of movies, you can also scroll through just sports, news shows or kids programming.
As is the case with previous TiVos, if there are channels you never watch, such as something in Korean or Russian, you can have TiVo remove them from your lineup. Shows on those channels will be filtered out of listings and searches. You can also do that with Internet services you have no interest in paying for.
Roamio also has a number of hardware improvements, mostly on the mid-level Roamio Plus ($400) and the high-end Roamio Pro ($600):
— Those two models will let you watch live or record up to six shows at once. That's up from a maximum of four. (The $200 base model has four tuners, up from two.)
— Both will let you watch your recorded shows on an iPhone or iPad. Before, you needed a separate $130 TiVo Stream box. Streaming is currently limited to iPhones and iPads connected to your home wireless network, but TiVo will start offering out-of-home streaming this fall. Users will be able to stream video in various ways, including through a hotel Wi-Fi on the road. Android streaming is promised by early next year.
— All three models come with a remote that uses radio signals rather than an infrared beam. What that means is you don't have to point the remote at the TiVo.
— All three models also have Wi-Fi built in, so you no longer need to attach an Ethernet cable or buy a separate TiVo Wi-Fi adapter for $90.
— The Roamio offers speed improvements over the previous model, which you'll notice when navigating menus. That said, the system did hang on me for a few seconds now and then as TiVo sifted through all the data.
The base model comes with 500 gigabytes of storage, enough for 75 hours of high-definition recordings. The Plus model, which is the one I reviewed, has 1 terabyte for 150 hours, while the Pro has 3 terabytes for 450 hours. That's nearly 19 days of TV without any sleep. There's even more room for non-HD recordings.
If you bought a new TiVo recently, you probably don't need to upgrade. If you want the streaming, you can simply buy the TiVo Stream device. It will get out-of-home streaming, too, when that's available. You can also get a device called the Slingbox, which essentially mirrors over the Internet what's being shown on your home TV. TiVo has at least one advantage over the Slingbox: It lets you and whoever's home watch different shows.
Roamio isn't compatible with satellite TV or video service through AT&T's U-verse.
It works with cable TV service, but you'll need to keep it. While the base model can accommodate over-the-air broadcasts, the Plus and the Pro models can't process signals from antennas. You would be stuck with TiVo as a streaming device, which isn't its strong suit. Both Roku and Apple TV offer access to many more Internet services than TiVo. TiVo is largely limited to Netflix, Hulu Plus, Amazon.com and a few others. That said, the Roamio has software changes that's designed to make future apps easier to write.
Game machines such as the Wii U and phones such as Samsung's Galaxy S4 offer apps that let you find shows and control the TV from the device. TiVo can replace your TV's remote, too, but it's expensive if that's all you want.
I have stopped channel surfing since I got my first TiVo in 2001. There's always something better to watch now that TiVo has helped me find and record programming. After just a few hours with Roamio, I was discovering even more shows and movies I want to watch.
And with streaming video, it does a good job of finding all that content. With one search, I can tell that Netflix has only the first four and a half seasons of "Breaking Bad." That same search tells me that if I want more recent episodes, I need to buy them through Amazon Instant Video or wait for reruns on AMC. With Roku, I have to search for online content one service at a time.
You can probably cobble together a bunch of services and devices that do what TiVo does. With the new Roamio, TiVo is the one that does it all and does it well.
The fifth-generation DVRs from TiVo Inc. comes in three flavors: a $200 basic model with 75 hours of high-definition recording, a $400 Roamio Plus with 150 hours and a $600 Roamio Pro with 450 hours. All three require TiVo service, which costs $15 a month with a one-year commitment, $20 a month with no commitment or a one-time payment of $500 for the life of the device.
The Plus and the Pro come with the ability to stream recorded shows on iPhones and iPads, with Android support to come. Initially limited to when you are connected to your home Wi-Fi network, the feature will work at hotels, at work and elsewhere this fall. The streaming feature replaces the need for a $130 TiVo Stream box. All three Roamio versions expand on TiVo's strengths in helping viewers find shows.
The Roamios are available online through TiVo, Amazon.com Inc. and Best Buy starting Tuesday. They will also hit Best Buy's physical stores in the coming weeks.
Anick Jesdanun, deputy technology editor for The Associated Press, can be reached at firstname.lastname@example.com.


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Ok. Now that I have a successful 100 under my belt again, it's time to turn thoughts to my second 100 of the year: Mohican 100 Trail Race. I DNF'd this race the two times I have attempted the 100 mile distance, both occurences due to timing out.
So, therefore, no big secret…I need to get faster at Mohican.
Aid Station Time
Aid Stations: The AS will not be the huge food spread that we had at Umstead. With Umstead being a loop, there was only the two AS (which you accessed 8 times each). Mohican is kind of a cloverleaf course. You do every Aid Station Twice, and the Covered Bridge, which is kind of at the center, multiple times.
I just went over the course, and the Aid Stations-19 aid stations! If you spend one minute in each AS, there is 19 minutes. I could have used a cushion of 19 minutes. You hit the Covered Bridge Aid Station 4 times. If you spend 5 minutes there-that's 20 minutes used of your racing time. I am starting to see where my race time went in the last two years…..
Both years I have timed out at Mile 75. I hit 15 AS before that. Eliminate Landoll's Castle, the first AS, which everyone just rolls through. Say I spent 5 minutes at each AS. There is 70 minutes! Holy cow!! One hour 10 minutes!!
Strategy: Roll through the AS. I think I will have my drop bags ready with food for me to eat. That way, I can eliminate the stopping, staring, and trying to figure out what I would like to have at the AS. If I pack the little baggies just right, I can grab the baggy, refill water bottles, and go.
I will try not to change socks or shoes unless it seems warranted. I will have them available, at both Rock Point and the Covered Bridge, if needed. Same with clothing, only if needed. I will have long sleeved shirts/hats/gloves available in drop bags.
Mohican is full of them. Unending. Not much flats here. Up and down. I need to get working on increasing my walking uphill pace. Right now, our field across the road is empty. (Sometimes we rent it out and there are horses pastured there). There is a great hill that I can do repeats on, so that is going to be a close to home workout!


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Perfect Inconveniences
- by WorldsImagine
- Rating:
- Published: 22 Apr 2014
- Updated: 28 May 2014
- Status: Complete
Ali Cross is different. She can see and hear things that other people can't. Communicating with the dead is only the beginning. Will she ever find a place where she belongs?
Join MovellasFind out what all the buzz is about. Join now to start sharing your creativity and passion
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My daughter is 4 days old. She is at higher risk of jaundice because my blood type is positive and hers is negative. When we got discharged from the hospital, her bilirubin level was 6.6, well below the 10.4 would have required bililights. They wanted me to take her to the pediatrician today to follow up on her bilirubin levels.
So, the pediatrician said that she looked a little yellow to her. And since she hasn't pooped since over a day ago, I need to replace two feedings with formula for three days to help her poop. This diagnosis was made before any blood tests of actual bilirubin levels. The pediatrician handed me a ton of free formula samples of various types she had lying around. She sent me to the lab to get my daughter's blood tested and is supposed to call me with the results later this afternoon.
The whole thing seems wrong to me! I am feeding on demand every 2-3 hours, sometimes more frequently. She had plenty of wet diapers. My milk only just truly came in late yesterday. She is gaining weight. I don't think one day is enough to base a pooping pattern on. I do not want to give her any formula!


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Maybe Terry Collins is giving Daniel Murphy a day to think over his defense, but he's not in the lineup for tonight's game against Florida.
Murphy's brain freeze set up Mike Stanton's game-winning grand slam. It also served notice Murphy remains a defensive liability and a man without a position.
GM Sandy Alderson said Murphy will not play winter ball to work on a position in hope of him mastering things during spring training.
Well, good luck with that.
Here's tonight's lineup:
Jose Reyes, SS
Justin Turner, 2B
David Wright, 3B
Scott Hairston, RF
Jason Bay, LF
Angel Pagan, CF
Lucas Duda, 1B
Mike Nickeas, C
Chris Capuano, LP


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Yesterday, we posted on the alleged Israeli missile attack on a Reuters "armored vehicle" in Gaza. If you haven't already read it, you should start by reading that post and looking at the photographs; this is an update.
As I said yesterday, the photographs that have been published of the Reuters vehicle do not seem to correspond to the attack described in news reports. That's a layman's view, but several readers with expertise in military ordnance have expressed the same opinion. This photo shows the roof of the vehicle that, according to the original accounts, was hit by two Israeli missiles. (Later news reports have said "one or two" missiles, presumably because there is no mark on the vehicle that could possibly represent a second missile.)
International news media are reporting the Israeli attack on the press vehicle as a fact. See, for example, this BBC story: "Israeli rocket hits Reuters car":
An Israeli air strike on a car in Gaza City during a security operation has injured a Reuters news agency cameraman and a local journalist. At least one rocket hit the car as the cameraman was filming, knocking him unconscious, while the second man received serious leg wounds.
The Reuters car was clearly marked all over as a media vehicle.
The Israeli army said the car had not been identified as press and expressed regret that journalists had been hurt.
Just in case anyone missed the point, the BBC repeats it:
[An IDF spokeswoman said:] "This car was not identified by the army as a press vehicle. If journalists were hurt, we regret it."
The Reuters armoured car was clearly labelled as a media vehicle, with signs on all sides, including the roof.
According to the Associated Press, the white sports utility vehicle was emblazoned with the Reuters logo and had "TV" and "Press" written on it in English, Arabic and Hebrew.
So the Israelis are liars, evidently. But the BBC never mentions that the incident took place in the middle of the night, so it is entirely likely that any markings on the vehicle would not have been visible.
The BBC describes the damage to the interior of the vehicle:
The front seats of the car were covered in blood, much of the inside of the vehicle was torn by shrapnel and one of the bullet-proof windows was completely destroyed, the agency says.
Here is the best picture I've seen of the interior of the vehicle:
I have a hard time correlating that description with the photo of the vehicle's interior. The inside of the vehicle looks like an old, junked van, just like the outside.
We did hear from one reader, who sounds like he may know what he's talking about and thinks Reuters's claim is plausible. Jim C. writes:
I was reading the article "Reuters Alleges Israeli Air Strike" and I have to disagree with Mike Weatherford. I retired last year after 24 years in Explosive Ordnance Disposal (EOD). I have years of experience with post blast investigations.The first photo of the Land Rover clearly shows evidence of an explosion. Looks to me like a hit from a 2.75″ HE rocket. The reason you don't see a "normal" entry hole is the warhead detonated after glancing off the truck. Many of the fuzes used have a graze sensitive feature, so that even if you don't get a good impact the secondary detonation train fires. The metal failed along the lines of least resistance. The pattern of damage is consistent with an explosion not in contact with the vehicle.
As for the rust in the next photo, I was a steel worker before I enlisted. High tensile strength steel easily flash rusts once the protective coating is removed.
I have no comment about the blood photos.
The last photo I believe Mike Weatherford is correct in his interpretation.
Valuable input. I'm still skeptical, however. The photos, taken as a whole, don't look to me like this vehicle was hit by a missile (or two) and suffered the damage described in news reports. As for the "flash rust," could this really happen in a matter of hours? In Gaza, in August, with no rain? As a non-metallurgist, I say No.
Another reader, Ted Carlson, joins the skeptical majority:
I spent twenty years in both military and civilian bomb disposal. The damage to the ambulance pictured in the article was NOT caused by any missile. Any missile that the Israelis have would completely destroy a vehicle like that ambulance. That hole in the roof looks like a couple of well placed hits with an axe.
A couple of readers have pointed out that Israel hasn't denied hitting the Reuters vehicle. That's true. But the IDF has a history of apologizing for alleged attacks that later turned out to be bogus. More important, Israel's admission that it fired at a vehicle that appeared to be involved in terrorist activity proves nothing at all. Israeli pilots can say that they fired at a vehicle, but they cannot say that the vehicle they fired at was the Reuters press van that is now being displayed by the Palestinians. Thus, Israeli newspapers have appropriately characterized the Reuters claim as a report by "Palestinian officials and residents."
As I said yesterday, I have no special expertise to evaluate claims of explosive damage. But the photographs of the Reuters vehicle that was allegedly bombed raise obvious questions about whether Reuters's claims are true. Almost all of our readers who have relevant experience have expressed great skepticism. So I draw two conclusions: 1) It is inappropriate for the world's press to report the Palestinians' claims as fact, when they are actually unproven allegations. 2) I hope the Israeli authorities will investigate this incident aggressively and determine the accuracy of Reuters's claims.
An important point lurks here: if the purported attack on a Reuters press van was a fraud–if, in fact, the Israelis fired on a terrorist vehicle, as they believed, and the Reuters van was dragged off a junk lot for propaganda purposes–then Reuters has crossed the line from being the dupe of a hoax–we know that's happened–to being the perpetrator of a hoax. It is worth some effort to find out whether that is the case.
UPDATE: More here.
FURTHER UPDATE: More here.


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November 2013 More than half of heroin-addicted patients treated with naltrexone via an implanted delivery device maintained abstinence throughout a 6-month clinical trial in Saint Petersburg, Russia. The implant device, which releases a steady dose of naltrexone continuously for 2 months, averted relapse to heroin use three times as effectively as daily oral doses of the medication.
February 2013 Despite the advances in treatment and prevention, roughly 50,000 new HIV infections still occur annually in the Nation. Research, in large part supported by NIDA, has produced a strategy to address this circumstance and break the epidemiological impasse: seek out HIV-infected individuals, particularly those in "hard-to-reach" groups that have minimal contact with the health care system; offer them HIV testing and treatment; and provide support to help them stay in treatment.
April 2010 Remembers Dr. James A. Inciardi, founder and co-director of the Center for Drug and Alcohol Studies and professor at the University of Delaware, who died on November 23, 2009.
April 2010 Reports trends in onset of injection drug use to infection with hepatitis C virus in developed countries and notes the influence of prevention efforts.
December 2009
Reports finding from a study showing that access to antiretroviral therapies, HAART in particular, can improve the health of HIV-infected patients who have a history of injection drug use.
November 2009 Highlights the disproportionately high rate of Americans who have used cocaine at some time during their lives as compared with other nations surveyed.
June 2008 Highlights the NIDA International Program which works to strengthen international research networks, creating opportunities for global research collaboration, training, and scientific exchange.
October 2007
Reviews a journal supplement that compiles studies on drug-related HIV transmission, with a focus on injection drug use, in 16 different localities across the globe.


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STOCKTON - Drivers on California roads on weekend nights are more likely to have drugs than alcohol in their systems, according to a results of a survey released by state officials on Monday.
STOCKTON - Drivers on California roads on weekend nights are more likely to have drugs than alcohol in their systems, according to a results of a survey released by state officials on Monday.
About 14 percent of drivers surveyed tested positive for drugs that could impair their ability to drive, according to the California Office of Traffic Safety. That's nearly twice as many drivers as the 7.3 percent who tested positive for alcohol, according to the survey.
The survey was the first of its kind in the state, but safety officials said it reinforced what other statistics have shown is a growing problem.
"While the use of alcohol while driving has been lessening, drugged driving has been growing," said Chris Cochran, an Office of Traffic Safety spokesman. Quantifying the problem with the survey is a step toward fighting it, he said. "This is just another step in determining how best to combat drugged driving."
Unlike with alcohol, there is no defined legal limit for the drugs - both legal and illegal - that can impair driving. Officers across the state undergo special training to help them detect drug-impaired drivers, according to safety officials. These include officers in Stockton, at DUI checkpoints and on patrol, said Officer Joe Silva, a Stockton Police Department spokesman.
It starts with recognizing the symptoms of drug use, then testing if the driver is impaired. "(Officers) will run a series of tests ... to see if drivers are under the influence," he said.
Whether a driver is under the influence of drugs or alcohol, Silva said, the negative consequences can be the same - arrest, jail or potentially fatal traffic accidents.
The percentage of drivers killed in crashes on California roads who test positive for drugs has been on the rise, according to the Office of Traffic Safety. In 2010, 30 percent of those killed drivers tested positive for legal or illegal drugs.
Survey results came from 1,300 drivers in nine cities who agreed to give breath and saliva samples between 10 p.m. and 3 a.m. on Friday and Saturday nights. Breath samples were tested for alcohol, while the saliva was tested for marijuana and a number of other drugs, legal and illegal.
Marijuana use was at 7.4 percent, slightly above the percentage of people testing positive for alcohol. Of the 7.3 percent of people testing positive for alcohol, 23 percent also tested positive for at least one other drug, a combination that could increase the effect of both substances.
Collecting information has helped in efforts to fight drunken driving, and it can do the same for drugged driving, officials said.
"We want people to know that it's not just alcohol; it's legal, illegal and over-the-counter drugs that can impair people," Cochran said.
Contact reporter Zachary K. Johnson at (209) 546-8258 or firstname.lastname@example.com. Visit his blog at recordnet.com/johnsonblog.


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More information on Post-Study Work Rights is available on the Department of Immigration and Border Protection website.
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#ardilaun hotel
Welcome to The Ardilaun Hotel
A Luxury 4 Star Hotel in Galway City
Welcome to The Ardilaun Hotel in Galway City and thank you for visiting our Official Website. Whatever the reason for visiting today we do hope you can navigate easily throughout our website. Contact us if you have any questions about any of our hotel services.
If you are looking to book a guestroom then browse through our hotel gallery and special offers to see our latest midweek, weekend, and golden years breaks. Book direct for best rates!
The 4 Star Ardilaun Hotel offer its guests many services including:
- 123 Modern Ensuite Guestrooms – take a look at our room gallery
- Free Parking
- Free Wi-fi throughout the hotel
- Workout or relax in The Ardilaun Leisure Club – facilities include swimming pool. sauna, steam, fitness classes etc
- Hotel with Kids Club our dedicated koala kids club offers enjoyment for all the family
- Book a relaxing treatment in our Avalon Beauty Salon
- Galway's finest Afternoon Tea served in our spacious lounge daily from 3-5pm. Booking advisable!
- The Ardilaun Bistro features boasts a popular menu with local artisan produce from West of Ireland suppliers
- Camilaun Restaurant overlooking mature gardens
- Extensive Conference Venue with excellent Banqueting facilities – meeting rooms available from 2 to 650 delegates!
- Popular Wedding Venue – stunning gardens for your wedding photographs
Nestled in the leafy suburbs of Galway, this traditional four star family owned hotel portrays contemporary style and is ideally located on the lovely environs of Taylor s Hill, only 1km from the bustling festival city of Galway, on the Wild Atlantic Way .
The Ardilaun Hotel is surrounded by lush gardens which makes the approach to the hotel particularly attractive. Taking a walk through the gardens after breakfast or before dinner, is a pleasure unique as a Galway city hotel.
Enjoy your stay in our luxury 4 star Hotel in Galway, and take advantage of our great value deals.
Over 50 s Breaks Great Value Offers Enjoy a 2 or 3 Night stay inclusive of dinner and breakfast each day from only 120 per person sharing.


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Silver is a valuable ore and metal in Skyrim. It can fashioned into accessories through smithing. It's also used to create silver weapons, which are strong against Werewolves and undead creatures.
To mine ores from mineral veins, you must have a pickaxe in your inventory. You don't need to equip it; just have it with you. Mines usually have pickaxes lying around and also you can purchase them from major merchants and stores.
EditMining Locations
- One of the easiest ways to get silver is to find members of the Silver Hand Faction and kill them, as most of them carry Silver Ingots. The higher level the enemy is, the more ingots.
- Cidhna Mine, reached during the No One Escapes from Cidhna Mine Quest in Markarth has 4-5 veins.
- Sanuarach Mine (NW in Karthwasten; Follow the path North from Karthwasten Hall: You will find Ainethach, and some villagers, and Atar, and his silver-hand group, confronting each other. After completing the quest, the mine will open.)
- This mine has 7 nodes. Depending on the results of the quest; the mine may have 1-2 low-level enemies. This mine does not have a marker on the map; you will need to fast-travel to Karthwasten.
- Fenn's Gulch Mine (NW in Karthwasten; to the right of the miner's barracks, NW of Karthwasten hall.)
- This mine has 1 vein, but no map marker.
Exit Theatre Mode


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An Egyptian leader who gets a lot of ass. Like A LOT of ass. There is literally no limit to the quantity of ass acquired by a thunderbitchen' pharaoh.
by Askthewizzard09 October 24, 2011
An ancient Egyptian Pharaoh that parties. One typically gets a lot of pussy; so much so that some would consider the amount obscene.
"Yo dawg, that guy gets entirely too much pussy"
"Man, homie be a thunderbitchen' pharaoh!"
"Man, homie be a thunderbitchen' pharaoh!"
by Kelsey0011 October 24, 2011


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I'm the author of several books, including Ice Mountain: An Elegy, Breakdown: Banjo Poems, Words on the Street: An Inaction Comic, and Odes to Tools, but my real work is at my literary blog Via Negativa. I'm the editor and publisher of Moving Poems, a webzine showcasing the best poetry videos on the web. More...
Follow via Email
Follow me on social media
Latest posts at Via Negativa
- Funeral procession September 5, 2018
- Makeover September 4, 2018
- Guerrilleros September 3, 2018
- Poet Bloggers Revival Digest: Week 35 September 2, 2018
- Paper pusher September 1, 2018
All writings by Dave Bonta are licensed under a Creative Commons Attribution-ShareAlike 3.0 United States License. For attribution, my name will suffice. Contact me for permission to waive the "share alike" provision (e.g. for use in a conventionally copyrighted work).


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Free Binding Mounting: We will mount you ski bindings for free whenever you order skis and bindings. If you order boots, too, we can adjust them so they are ready to hit the slopes right out of the box! Just be sure to fill out the mounting form that comes up after checkout.
Ideal Target Skier: Big Mountain Charger: Top speed, all the time, regardless of terrain, obstacles or children in the way, these skiers need stability on par with professional downhill racers. They are usually looking for long skis that are wide and heavy.
Sandwich Construction (SW): SW means that the sides of the skis are a vertical wall rather the the rounded Cap construction forund on most skis. Since none of the skis material needs to be exerting force maintaining shape at the edges, SW skis are stiffer than their Cap counterparts. Most people find SW skis to be damper, that is more glued to the snow, superior at high speed GS turns and top notch at busting through crud or choppy snow.
ISS Independent Suspension System: Elastomeric vibration killers located in the tip, tail and underfoot. The elastomers quiet the vibrations that are commonly associated with rockered skis. Underfoot, the vibrations are dampened to provide the skier with a smooth ride.
Ideal Target Skier: Powder Hound: If you use your sick days only when it snows 12'' or more overnight and not when you're actually sick, this ski is probably for you. Powder Hounds are on the search for deep and untouched powder, and fat skis to ski it with.
Tail Rocker: Just like Tip rocker, but in the tail, this feature allows the tails of the skis to release easier from the turn to give the skier the ability to turn the skis quicker in tight spots. It also allows skiers to dump speed by forcing the tails out and sliding sideways. The effective edge is reduced because of the tail rocker, so the skis will also be easier to control when forced to ski on the groomed slopes.
Extra Durable ABS Sidewalls: Because extra durability is never bad, right? RIGHT?!?!?!
Tip Rocker: This refers to the early rising of the tip to get the ski on top of the soft snow, rather than pushing through it. When the skis are held with the bases together, it will look like the tips are bent, and spread away from eachother. Tip rocker also helps skiers pivot the skis, making tight trees remarkably easy, and gives the ski a surf-like feel.
TNT Rocker: Tip and tail rocker combined with regular camber underfoot. This combination creates a surfy feel in powder while maintaining hard snow versatility. 40% Rocker, 60% Camber{block type="cms/block" block_id="smi_ski_uhm_c_base"}}
Expert Binding Choices: Some of the binding options (i.e. the Head GTO 15) available for this ski have high din ranges that start at 8 or 9. A very small percentage of skiers will be suitable for these bindings. If you know that you usually set your din at 8 or above, you are in the clear for a high din binding. Otherwise, those bindings are for EXPERT SKIERS ONLY!
Wood Core: The standard core which has throughout time provided the best performance and durability. Each model may have it's own density level to help define flex and maximum speed but every wood core ski will be solid.
TTS Technology: A stabilizing layer in the ski that dampens vibrations normally felt from rockered tips and tails. This unique feature to Head also adds torsional stiffness and increases performance in everything from crud to hard snow.
3 Choice Mount Position : The three choices are as follows. Park Mount is where the bindings are closer to dead center on the ski and is best for freeride skiers who want to ski switch a lot of the time. Manufacturer's mount is where the makers of the ski recommend you mount the bindings (usually between park and powder mount). Finally Powder mount is the furthest back on the ski which allows for more tip length and float in powder. If you wish to get more technical on where we mount your skis, please contact customer service.
Additional Info
|Ability Level
|Advanced, Expert
|Terrain Type
|All Mountain, Powder
|Discount range
|> 70%
|Model Year
|Waist Width Range
|Includes Ski Bindings
|Twin Tip
|Rocker Type
|International Availability-Prices USD
|United States, Canada, Australia/New Zealand/Chile/Argentina, UK, Ireland, Japan
|Country of Manufacturer
|Manufacturers one year standard warranty


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LU presents first TSUS Staff Excellence Award
Donna Blaisdell, executive assistant to the director of the Mary and John Gray Library, earned honors Tuesday as Lamar University's first recipient of The Texas State University System Staff Excellence Award.
Blaisdell is a resident of Lumberton and a 28-year veteran of the Lamar staff.
Five other LU employees earned Distinguished Staff Awards at Lamar's annual staff recognition program.
The awards were presented April 16 during a reception and program hosted by the Staff
Advisory Council in the University Reception Center of the Mary and John Gray Library. The program also featured the presentation of 110 service awards and recognition of 16 retirees. Distinguished Staff Award recipients are Kathleen Hawsey of Bridge City, Rachel Juneau of Nederland, Shannon Klutts of Port Neches, Ashley Spicer-Runnels of Beaumont and Marsha Williams of Beaumont.
* Hawsey is an administrative associate in the Department of Student Engagement.
* Juneau is an executive assistant in Strategic Enrollment Management.
* Klutts is coordinator of the master of business administration program and graduate certificate office in the College of Business.
* Spicer is director of Student Development and Leadership.
* Williams is laboratory coordinator for the Department of Chemistry and Biochemistry and hazardous waste manager for the Department of Environmental Risk Management.
The TSUS Staff Excellence Awards were established to recognize and reward support-staff employees of the system for outstanding contributions to the TSUS mission and that of its component institutions.
Criteria for selecting Distinguished Staff Award recipients include:
Performance and initiative – The employee must consistently produce quality work and exhibit a high level of commitment to the department and the university as a whole. This personal investment is demonstrated through individual resourcefulness, as well as collaboration, cooperation and teamwork. Often, the employee makes personal sacrifice or goes above and beyond what is required for a particular job.
Positive attitude and relationships – The employee must have a positive and dedicated attitude that enhances morale and be consistently respectful, compassionate and dignified. He or she unfailingly demonstrates a spirit of fairness in a culturally diverse environment.


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Student Engagement Mission
Student Engagement: Mission & Philosophy
The mission of the Office of Student Engagement is to design and implement comprehensive programs that enhance the overall educational experiences of students through the development of, exposure to and participation in social, cultural, multicultural, intellectual, recreational, community service, leadership abilities and campus governance involvement.
The office delivers comprehensive programs and services designed to meet the co-curricular needs of our diverse student population. We strive for excellence in the delivery of high quality programming, leadership activities, and effective facility and resource management.
Consistent with the University's mission of research, education and service, our goal is to expose students to diverse events, that address the different facets of life within the campus community including involvement with individual students, the Student Government Association, student organizations, the Campus Activities Board, faculty, staff, administration, alumni and friends.
The departmental staff of the Office of Student Engagement enhances the development of student life skills by promoting involvement, community awareness, service, cooperative programming and leadership opportunities. We value our role as educators in the campus community, and advocate and embrace the appreciation of diversity, values and exploration. In addition, the staff is encouraged to participate in ongoing staff development and training.
"Two thirds of a college student's waking hours is devoted to activities other than attending classes or studying… alumni frequently report that out-of-class experience increased their competence and assurance".
George D. Kuhl. et al