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Dorry Segev, M.D., Ph.D.
Dorry Lidor Segev, M.D., Ph.D.
Associate Vice Chair for Research
Professor of Surgery
Languages: English, Hebrew
Expertise: Abdominal Surgery, Incompatible Kidney Transplant, Kidney Transplant, Minimally Invasive Live Donor Surgery, Minimally Invasive Surgery, Pancreas Transplant, Transplant Surgery, Vascular Surgery ...read more
Research Interests: Disparities in access to transplantation; Outcomes after kidney, liver, and pancreas transplantation; Mathematical simulation, modeling, and optimization; Advanced biostatistical methods, decision analysis and Markov models; Kidney transplantation and renal failure in the elderly; Kidney paired donation (living donor kidney exchange); Incompatible Kidney Transplantation; Allocation of non-directed donors; Expanding utilization of expanded criteria organs; Donor-recipient matching; Gender disparities in transplantation; Organ preservation solutions; Decision-making algorithms for high infectious risk donors; Safety and long-term survival in living kidney donors ...read more
Johns Hopkins Outpatient Center
601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 443-287-7789
Fax: 410-510-1526
Dr. Dorry Segev is an abdominal transplant surgeon focusing on minimally invasive live donor surgery and incompatible organ transplantation. His research uses advanced statistical methods for mathematical modeling and simulation of medical data, analysis of large healthcare datasets, and outcomes research. He has made significant contributions to the field of transplantation including development of a mathematical model to facilitate a nationwide Kidney Paired Donation program in both the US and in Canada. He is an NIH Clinical Research Scholar, American Geriatrics Society Dennis Jahnigen Scholar, National Institute of Aging Paul Beeson Scholar, senior investigator for the Scientific Registry for Transplant Recipients, and Doris Duke Clinical Scientist Development Award recipient for his groundbreaking work in clinical decision-making for renal failure patients over 65. He has authored more than 250 peer-reviewed research articles in journals including New England Journal of Medicine, JAMA, American Journal of Transplantation, Annals of Surgery, Journal of the American Society of Nephrology, and others. He is an Associate Editor for American Journal of Transplantation, American Journal of Kidney Diseases, and Liver Transplantation. His work is regularly featured in widely read media including TIME magazine, the Discovery Channel, US News & World Report, and the New York Times.
- Associate Vice Chair for Research
- Director, Epidemiology Research Group in Organ Transplantation
- Professor of Surgery
Departments / Divisions
- Surgery - Transplant Surgery
Centers & Institutes
- MD, Johns Hopkins University School of Medicine (1996)
- Johns Hopkins University School of Medicine / Surgery (2004)
Research & Publications
Lab Website: Epidemiology Research Group in Organ Transplantation
Selected PublicationsSegev, DL, Gentry SE, Warren DS, Reeb B, Montgomery RA. Kidney Paired Donation and optimizing the use of live donor organs. JAMA. 2005 Apr 20; 293 (15) 1883-90.
Gentry SE, Segev DL, Montgomery RA. A comparison of populations served by Kidney Paired Donation and List Paired Donation. Am J Transplant. 2005 Aug; 5(8): 1914-21
Segev DL, Simpkins CE, Warren DS, King KE, Maley WR, Melancon JK, Cooper M, Kozlowski T, Montgomery RA. ABO incompatible high-titer renal transplantation without splenectomy or anti-CD20 treatment. Am J 2005 Oct;5(10):2570-75.
Segev DL, Gentry SE, Melancon JK, Montgomery RA. Characterization of waiting times in a simulation of kidney paired donation. Am J Transplant. 2005 Oct; 5(10):2448-55.
Montgomery RA, Zachary AA, Ratner LE, Segev DL, Hiller JM, Houp J, Cooper M, Kavoussi L, Jarrett T, Burdick J, Maley WR, Melancon JK, Kozlowski T, Simpkins CE, Phillips M, Desai A, Collins V, Reeb B, Kraus E, Rabb H, Leffell MS, Warren DS. Kidney Paired Donation permits successful transplantation with incompatible live kidney donors. JAMA. 2005 Oct 5;294(13):1655-63.
Montgomery RA, Gentry SE, Marks WH, Warren DS, Hiller J, Houp J, Zachary AA, Melancon JK, Maley WR, Rabb H, Simpkins CE, Segev DL. Domino paired kidney donation: a strategy to make best use of live non-directed donation. Lancet. 2006 Jul 29;368:419-21.
Simpkins CE, Montgomery RA, Hawxby AM, Gentry SE, Locke JE, Warren DS, Segev DL. The Effect of Cold Ischemic Time on Live Donor Renal Transplantation: Is Organ Transport Feasible for Live Donors? Am J Transplant. 2006.
Segev DL, Gentry SE, Montgomery RA. Association between waiting times for deceased donor kidney transplantation and rates of live donation. Am J Transplant. 2007 Oct;7(10):2406-13.
Gentry SE, Segev DL, Simmerling M, Montgomery RA. Expanding kidney paired donation through voluntary participation by compatible donors. Am J Transplant. 2007 Oct;7(10):2361-70.
Segev DL, Maley WR, Simpkins CE, Locke JE, Montgomery RA, Nguyen GC, Thuluvath P. Minimizing risk associated with elderly liver donors by matching to preferred recipients. Hepatology. 2007 Dec;46(6):1907-18.
Segev DL, Simpkins CE, Thompson RE, Locke JE, Warren DS, Montgomery RA. Obesity impacts access to kidney transplantation. J Am Soc Nephrology. 2008 Feb;19(2):349-55.
Segev DL, Kucirka LM, Nguyen GC, Cameron AM, Locke JE, Simpkins CE, Thuluvath PJ, Montgomery RA, Maley WR. Effect modification in liver allografts with prolonged cold ischemic time. Am J Transplant. 2008 Mar;8(3):658-66.
Segev DL, Sozio S, Shin EJ, Nazarian SM, Nathan H, Thuluvath PJ, Cameron AM, Montgomery RA, Maley WR. Steroid avoidance in liver transplantation: meta-analysis and meta-regression of randomized trials. Liver Transplantation. 2008 Apr;14(4):512-25.
Segev DL, Montgomery RA. Regional and Racial Disparities in the Use of Live Non-Directed Kidney Donors. Am J Transplant. 2008 May;8(5):1051-5.
Segev DL, Kucirka LM, Gentry SE, Montgomery RA. Current practice of kidney paired donation in the United States. Transplantation. 2008 Aug 27;86(4):502-10.
Montgomery RA, Katznelson S, Bry WI, Zachary AA, Houp J, Hiller JM, Shridharani S, John D, Singer AL, Segev DL. Successful three-way kidney paired donation with cross-country live donor organ transport. Am J Transplant. 2008 Oct;8(10):2163-8.
Segev DL, Thompson RE, Locke JE, Simpkins CE, Thuluvath PJ, Montgomery RA, Maley WR. Prolonged waiting times for liver transplantation in obese patients. Ann Surg. 2008 Nov;248(5):863-870.
Stewart ZA, Cameron AM, Signer AL, Dagher NN, Montgomery RA, Segev DL. Histidine-Tryptophan-Ketoglutarate (HTK) is associated with reduced graft survival in pancreas transplantation. Am J Transplant. 2009 Jan;9(1):217-221.
Locke JE, Montgomery RA, Warren DS, Segev DL. Renal transplantation in HIV-positive recipients: long-term outcomes and risk factors for graft loss. Arch Surg. 2009 Jan;144(1):83-86.
Stewart ZA, Cameron AM, Signer AL, Montgomery RA, Segev DL. Histidine-Tryptophan-Ketoglutarate (HTK) is associated with reduced graft survival in deceased donor livers, especially those donated after cardiac death. Am J Transplant. 2009 Feb;9(2):286-293.
Kucirka LM, Alexander C, Namuyinga R, Hanrahan C, Montgomery RA, Segev DL. Viral nucleic acid testing (NAT) and OPO-level disposition of CDC high-risk donor organs. Am J Transplant. 2009 Mar;9(3):620-8.
Kucirka LM, Namuyinga R, Hanrahan C, Montgomery RA, Segev DL. Formal policies and special informed consent are associated with higher provider utilization of CDC high-risk donor organs. Am J Transplant. 2009 Mar;9(3):629-35.
Lonze BE, Warren DS, Shah A, Stewart ZA, Dagher NN, Singer AL, Montgomery RA, Segev DL. Kidney transplantation in previous heart or lung recipients. Am J Transplant. 2008 Mar;9(3):578-85.
Segev DL, Kucirka LM, Oberai PC, Parekh RS, Boulware LE, Powe NR, Montgomery RA. Age and comorbidities are effect modifiers of gender disparities in renal transplantation. J Am Soc Nephrology. 2009 Mar;20(3):621-8.
Rees MA, Jopke JE, Pelletier RP, Segev DL, Rutter ME, Fabrega AJ, Rogers J, Pankewycz OG, Hiller J, Roth AE, Sandholm T, Unver U, Montgomery RA. A non-simultaneous extended altruistic donor chain. NEJM. 2009 Mar 12;360(11):1096-101.
Stewart ZA, Lonze BE, Warren DS, Signer AL, Dagher NN, Montgomery RA, Segev DL. Histidine-Tryptophan-Ketoglutarate (HTK) is associated with reduced graft survival of deceased donor kidney transplants. Am J Transplant. 2009 May;9(5):1048-54.
Kucirka LM, Namuyinga R, Hanrahan C, Montgomery RA, Segev DL. Provider utilization of high-risk donor organs and nucleic acid testing: results of two national surveys. Am J Transplant. 2009 May;9(5):1197-204.
Gentry SE, Montgomery RA, Swihart BJ, Segev DL. The roles of dominos and never-ending altruistic donor chains in kidney paired donation. Am J Transplant. 2009 Jun;9(6):1330-6.
Thuluvath PJ, Maheshwari A, Thuluvath NP, Nguyen GC, Segev DL. Survival after liver transplantation for hepatocellular carcinoma in MELD and pre-MELD eras and the independent impact of HCV. Liver Transplantation. 2009 Jun 26;15(7):754-762.
Massie AB, Zeger SL, Montgomery RA, Segev DL. The effects of DonorNet 2007 on kidney distribution equity and efficiency. Am J Transplant. 2009 Jul;9(7):1550-7.
Stewart ZA, Locke JE, Montgomery RA, Singer AL, Cameron AM, Segev DL. ABO-incompatible deceased donor liver transplantation in the United States: a national registry analysis. Liver Transplantation. 2009 Jul 29;15(8):883-93.
Melancon JK, Kucirka LM, Boulware LE, Powe NR, Locke JE, Montgomery RA, Segev DL. Impact of Medicare coverage on disparities in access to simultaneous pancreas and kidney transplantation. Am J Transplant. 2009 Dec;9(12):2785-91.
Segev DL, Muzaale AD, Caffo B, Mehta S, Taranto SE, McBride MA, Montgomery RA. Short-term and long-term survival in a 15-year cohort of all live kidney donors in the United States. JAMA. 2010 Mar 10;303(10):959-66.
Grams ME, Womer KL, Ugarte RM, Desai NM, Montgomery RA, Segev DL. Listing for expanded criteria donor kidneys in older adults and those with predicted benefit. Am J Transplant. 2010 Apr;10(4):802-9.
Kucirka LM, Ros RL, Subramanian AK, Montgomery RA, Segev DL. Provider response to a rare but highly publicized transmission of HIV through solid organ transplantation. Arch Surg. In press.
Kayler LK, Segev DL. The impact of nonidentical ABO deceased-donor kidney transplantation on kidney utilization. Am J Kidney Dis. In press.
Kucirka LM, Singer AL, Ros RL, Montgomery RA, Dagher NN, Segev DL. Underutilization of hepatitis C positive kidneys for hepatitis C positive recipients. Am J Transplant. In press.
Activities & Honors
- Inducted, American Society for Clinical Investigation, 2012
- Mid-Level Faculty Award, American Society of Transplant Surgeons, 2012
- Maryland Top 40 Professionals Under 40, Maryland Daily Record, 2010
- New Key Opinion Leader, The Transplantation Society, 2009
- John Merrill Award in Transplantation, American Society of Nephrology, 2009
- Julius Jacobson Promising Investigator Award, American College of Surgeons, 2009
- Clinical Scientist Development Award, Doris Duke Charitable Foundation, 2008
- Dennis W Jahnigen Scholars Award, American Geriatrics Society, 2007
- Vanguard Prize, American Society of Transplant Surgeons, 2006
- Clinical Science Faculty Award, American Society of Transplantation, 2006
- Science of Hope Medicine Compassion Award, Johns Hopkins Transplant Center, 2006
Videos & Media
Living Donor Kidney Transplant
Meet Our Expert: Dr. Dorry Segev
Recent News Articles and Media Coverage
Dr. Dorry Segev is one out of the four physicians featured in this article who began his career in a field other than medicine. Read about his journey.
Patient Ratings & Comments
The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
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Intelligence officer shot dead in northern Yemen
September 6, 2013
SANAA, Yemen (AP) — Security officials say militants have killed a high-level Yemeni intelligence officer working near the country's border with Saudi Arabia.
Officials say Lt. Col. Omar Mahmoud was walking to his car after midday Muslim prayers on Friday when gunmen on a motorcycle shot him to death in the province of Hadramawt in the city of al-Qatn.
The officials spoke on condition of anonymity because they were not authorized to speak to the media.
The Yemeni military has waged an offensive in the province to try to stop al-Qaida militants from taking over towns there in June.
The United States has also launched dozens of drone strikes in Yemen, killing at least six suspected al-Qaida militants in Hadramawt just last month.

subset: commoncrawl


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CACHED, Eastman Professor John Fetter Awarded for their Commitment to Diversity
The Center for Advocacy, Community Health, Education and Diversity (CACHED), led by Adrienne Morgan, and John Fetter, assistant professor of music education at the Eastman School of Music, will be honored as the 2012 Presidential Diversity Award recipients at 6 p.m. on Friday, Jan. 27, as part of the University of Rochester's Martin Luther King Jr. Commemorative Address in Strong Auditorium.
Both awardees were chosen for their commitment to building strong connections between the University and the Rochester community. CACHED was praised for providing visible leadership for the School of Medicine and Dentistry's diversity and community outreach initiatives, while Fetter was recognized for his work with the Urban Strings program at Rochester City School No. 17.
"Part of the institution's mission includes creating an environment that encourages individuals to contribute and improve the quality of life for others," said University President Joel Seligman. "I am grateful to both recipients for their dedication to building sustainable programs and initiatives that are of great service to members of both the University community and the Greater Rochester community."
CACHED, which is a division of the Offices for Medical Education, provides leadership for SMD diversity and outreach initiatives through a variety of approaches, including community engagement, pipeline programs, affinity groups for medical students, and diversity activities.
In a letter nominating CACHED for the award, Dr. David Lambert, senior associate dean of medical student education, wrote that the center has "created a supportive and responsive environment for students from diverse backgrounds" and has a "well-documented history and commitment of designing effective interventions to respond to community needs and to assist individuals most in need."
Dr. Linda Chaudron, senior associate dean for diversity, wrote that CACHED is a "cornerstone of the medical school's diversity efforts at the early end of the educational spectrum," citing their "stellar efforts to engage underrepresented students in considering a medical career through education pipeline programs," such as the Summer Undergraduate Research Fellowship and the Science and Technology Entry Program.
CACHED also was praised for its advocacy of student participation in service learning activities in the community, including the Free School, Work Permit, and Sports Physicals outreach program. Through this program, faculty and student volunteers provide free physical examinations and physician clearance to attend school and participate in sports for students in the Rochester City School District who may not have access to a doctor. CACHED coordinates six sessions for students, providing more than 700 free physicals each year. "CACHED, in conjunction with the dedicated student volunteers, has had a sustained and transformative impact on diverse populations and underserved individuals in Greater Rochester," wrote Brenda Lee, assistant dean for medical education and student affairs.
As a master's degree student at the Eastman School of Music, John Fetter became a leader and advocate for the Urban Strings program, which provides private or small group lessons to string students in grades three through seven at Enrico Fermi School No. 17. Now a member of Eastman's faculty, Fetter makes weekly trips to the school, where he coaches current Eastman students as they teach the children. In a letter nominating Fetter for the Diversity Award, Elizabeth Hanan, an Eastman alumna and teacher at School 17 wrote that Fetter is the "driving force behind organizing the Eastman teachers and getting them ready to be successful in the urban teaching environment."
In addition to the strings program, Fetter has been an active member of the Eastman School's Committee on Diversity and Inclusion. Ellen Koskoff, professor of ethnomusicology at Eastman and a member of the committee, wrote that Fetter is a strong member of the committee, always ready to "present different perspectives on the diversity issues confronting schools of music."
Fetter also delivered a presentation during the University's 2011 Diversity Conference, using his violin to demonstrate the many musical styles that can be associated with one instrument and the varying biases audiences develop toward different styles. He used this concept as a springboard to create dialogue about broader issues of diversity.
"John is a violinist, conductor, and educator with a mission," wrote Jamal Rossi, Eastman School executive associate dean, in a nomination letter. "He is deeply dedicated to urban education, demonstrating for our students and faculty a philosophy of teaching that he lives out every day."
The Presidential Diversity Awards were created in 2009 by Joel Seligman to recognize faculty, staff, students, units, departments or teams that "demonstrate a commitment to diversity and inclusion through recruitment and retention efforts, teaching, research, multi-cultural programming, cultural competency, community outreach activities, or other initiatives." This year's winners were chosen from among nine nominees who were recommended by their colleagues. The recipients and other nominees also were honored at a reception with the president and other University leaders yesterday at the Witmer House.
Each Presidential Diversity Award includes a $2,500 prize; individual award winners will receive half and will designate half to support the budget of a program or department of the winner's choice. Team award winners will designate the entire $2,500 prize to the program or department of the team's choice.
"The nominees for the 2012 award have impacted the lives of the faculty, staff, and students by helping us appreciate the value of diversitywithin our University and the greater Rochester community," said Dr. Vivian Lewis, deputy to the president and vice provost for Faculty Development and Diversity and chair of the award's selection committee. "CACHED and John Fetter stood out from this field of outstanding nominees for their ongoing dedication. We hope their examples will serve to inspire others to become involved in making the environment more inclusive. "


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Abduction attempt reported in Goffstown
November 18. 2013 10:35PM
GOFFSTOWN — A woman who told a driver she didn't want a ride fought off the same man after he returned and tried to pull her into his car Monday night, police said.
Police say the woman was approached by the man around 7:10 p.m. on Daniel Plummer Road near Cote Avenue. The woman said the driver left the area after she refused his offer for a ride, but returned and grabbed her.
Police said the woman was able to break free of the man, run away and call police.
The vehicle was described as a dark-colored, four-door vehicle.
A Nixle message was sent out to alert members of the community.
Anyone with information is asked to call Goffstown police at 497-4858.


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**1/2 (out of four)
The people behind "The Guilt Trip" should feel proud, not guilty, for the places the comedy doesn't go.
During an eight-day, cross-country road trip, Andy (Seth Rogen) and his overbearing mom, Joyce, (Barbra Streisand) don't, say, accidentally eat pot brownies and stay out all night. They don't hit a deer. The script from "Crazy Stupid Love" writer Dan Fogelman affectionately incorporates some Jewish humor without turning Joyce into a caricature.
Of course, "The Guilt Trip" does include a detour involving a topless bar (which, in order to maintain the PG-13 rating, contains zero topless women) that Joyce at first thinks advertises "tapas." In the car the pair listens to an audio book of Jeffrey Eugenides' "Middlesex" and Joyce initiates numerous conversations about her past sex life. The big joke "The Guilt Trip" has up its sleeve is Andy's awkwardness, and frequently the humor feels so sitcommy I expected to hear a laugh track.
But the movie's heart is in the right place. Initially planning to hit the road from New Jersey to Las Vegas to sell his FDA-approved, poorly named cleaning product Scieoclean, Andy invites his mom to join him when she confesses that he was named after the love of her life—whom Andy tracks to San Francisco. Hiding this ulterior motive from mom screams of "plot device," but "The Guilt Trip" doesn't overplay the revelation. Like many mothers of any religion, Joyce dotes on her son—she tells him "Good luck, sweetheart," in front of one of his potential buyers—and hopes that he'll appreciate her the way she adores him.
While not as funny as it should be, "The Guilt Trip" is sweet and adult enough to admit that a parent's advice, even if it's unsolicited, is often good just the same.
Watch Matt on "You & Me This Morning," Friday at 6:55 a.m. on WCIU, the U
Want more? Discuss this article and others on RedEye's Facebook page.


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Janine Nabers is Hartford Stage's new Aetna New Voices Fellow, a season-long position previously held by Pulitzer Prize-winning playwright Quiara Alegria Hudes, as well as Daniel Beaty, Will Power and Martthew Lopez.
The fellowship allows playwrights to develop work and become involved in the ongoing life of Greater Hartford. The residency includes working with the theater's education department, advancing community development, and the commissioning of a new play, as well as a series of readings and workshops throughout the year.
Nabers' newest play "Welcome to Jesus" will be part of "Brand:NEW," Hartford Stage's annual play reading festival. Her play "A Swell in the Ground" was presented in last year's festival.
The 2012-13 Aetna New Voices Fellow Matthew Lopez's "Somewhere" is making its East Coast premiere at Hartford Stage this spring. Poet and playwright Marcus Gardley, whose play "The House That Will Not Stand" runs this spring at Yale Rep, served as the 2011-12 fellow. "Fetch Clay, Make Man," by 2010-11 fellow Will Power, just opened at off-Broadway's New York Theatre Workshop. Hudes, the 2008-09 fellow, won the 2012 Pulitzer Prize for Drama for "Water by the Spoonful," a work which premiered at Hartford Stage. "Breath and Imagination" by 2007-08 fellow Daniel Beaty premiered last season.
The Houston-born Nabers is a 2013 graduate of the Lila Acheson Wallace Playwriting Fellowship at Juilliard. Her play "Annie Bosh is Missing" premiered in August 2013 at Chicago's Steppenwolf Theatre Company. A 2012-2013 New York Theatre Workshop Playwriting Fellow, she is also a member of the MCC Playwrights Coalition and the Dorothy Strelsin New American Writers Group at Primary Stages. She was Page 73's 2011 Playwriting Fellow and is an alumna of the Ars Nova Playgroup, the Soho Rep Writer/Director Lab, the Dramatists Guild Playwriting Fellowship, the MacDowell Colony Fellowship, and the 2010 and 2011 Sundance Theatre Labs.
Her musical "Mrs. Hughes" about Sylvia Plath and Ted Hughes was developed as the 2012 Williamstown Theatre Festival fellowship musical and was part of the 2013 Yale Institute for Musical Theatre, Manhattan Theatre Club's 7@7 series, and the Theatreworks New Works Now Festival.
Presently Janine is working on commissions from Playwrights Horizons and Berkeley Rep.


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DENVER (AP) — Kyrie Irving and the Cleveland Cavaliers used a balanced offensive attack to close out a successful Western Conference road trip.
Irving scored 23 points, Tristan Thompson had 20 points and 10 rebounds and the Cavaliers beat the Denver Nuggets 117-109 on Friday night.
Cleveland had five players score in double figures. C.J. Miles added 19 points, including four free throws down the stretch, and Luol Deng scored 18.
"Everyone has to be guarded," Irving said. "It's a luxury right now."
The Cavaliers finished their five-game trip with a 3-2 record after winning in Denver for the second time in three years. They led most of the way and held off a late rally by the Nuggets that cut a double-digit lead to three early in the fourth quarter.
Cleveland went 28 for 35 at the free-throw line, including 12 of 15 in the fourth quarter.
"We had each other's back because on the road it's us against the world," coach Mike Brown said. "We had a lot of guys step up. We were aggressive with 35 free-throw attempts."
Wilson Chandler scored 23 points and Ty Lawson had 19 points and 11 assists for the Nuggets, who have dropped two of three. Denver had won its last four home games, but fell to 11-9 at Pepsi Center this season. It had a 38-3 home record last season.
"These games should be in the win column," Lawson said. "We just keep letting easy games go. Our last month is tough, we've got to get these games right now."
The Nuggets attempted a season-high 37 3-pointers, making 14, but struggled from long range down the stretch.
"We were taking what the defense was giving us," Nuggets coach Brian Shaw said. "In the second half we threw up a lot because we were down and we were trying to get back in the game. But I don't think our offense was hurting us - it was defense."
After Tyler Zeller's free throw made it 94-86 with 9:33 remaining, Evan Fournier hit a floating jump shot in the lane and Nate Robinson made a 3-pointer to cut the deficit to three. It was the closest Denver had been since the second quarter.
"We still had the lead. The momentum was in their favor but that happens on the road, especially against a good home team," Irving said. "We had to remain aggressive and that's what we did."
The Cavaliers responded with five straight points. Anderson Varejao hit a jumper and free throw and Irving also scored to make it 99-91.
Denver made a couple more charges, but each rally fizzled when it got close.
Chandler hit two 3-pointers to help the Nuggets get within three at 111-108. Denver had a chance to get within one or tie but an offensive rebound by Irving led to a dunk by Deng with 43.8 seconds left, and Cleveland closed it out from there.
"We wanted it and we went out and took it," Irving said. "Couple of mistakes at the end but it didn't rattle us."
The Cavaliers led by 14 in the third quarter but Denver made a push to close to 87-80 heading into the fourth. Chandler scored seven points in the period.
Irving, Thompson and Miles all had 13 points in the first half for Cleveland, which used an 18-6 run to take a 68-57 lead at the break. Irving scored 10 points in the spurt and Miles hit a corner 3-pointer just before the end of the quarter to push the lead to 11.
The Nuggets hit nine 3-pointers in the first 24 minutes to keep it close but allowed the Cavaliers to hit 56.5 percent from the field in allowing 68 points in the first half for the second time this season.
Randy Foye led Denver with 14 points at the break.
"That second quarter we gave them 42 points," Foye said. "That just killed us. Every other quarter we held them down. That second quarter killed us."
NOTES: Nuggets F Darrell Arthur (left groin strain) missed his third straight game. ... Deng is averaging 18 points since coming to the Cavaliers in a trade with Chicago on Jan. 7. ... Shaw missed shootaround with a sinus infection but was on the sideline for the game.


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NetWellness is a global, community service providing quality, unbiased health information from our partners. NetWellness is commercial-free and does not accept advertising.
Tuesday, September 15, 2015
Esophageal Cancer
GERD and esophageal cancer
I have GERD so I am a little worried about getting esophageal cancer. What are some things I could do to help prevent this?
There are 2 types of esophageal cancer. The more common type in the US is adenocarcinoma, which has been linked to gastroesophageal reflux disease or GERD.
We must remember that the overall risk of developing cancer in patients with GERD is extremely low. However, it is also important to see your physician if those symptoms of GERD persist. If, after medical management, there is no improvement, your physician may recommend an esophagoscopy. If there is evidence of changes in the lining of the esophagus, then it would be important to obtain endoscopies at regular intervals.
Although it has never been proven that good control of GERD can reduce the incidence of cancer (it would take a trial of many thousands of patients to show that), it is still reasonable to assume that diminishing the injury from reflux is helpful. Dietary control, weight management, and using antireflux medications may all help reduce the long-term effects of GERD.
Abbas Abbas, MD
Assistant Professor of Surgery
College of Medicine
The Ohio State University


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Designers from around the world are submitting creative designs for JuliaF in logo design - custom.
Need a graphic that can be used as the visual representation of the doctor's practice.
none, just doctor's name is Val Kravtsov, DC or Valerian Kravtsov, Chiropractic Physician. Website is docval.com
1. As far as colors, we are still flexible, but would like to stay with neutral versions (earthy) of either green/orange, blue/green or any combination thereof.2. We are looking for a "soothing" feel but with a very contemporary design. Simplicity is KEY.3. Our website is docval.com and we do need that text to be incorporated with the logo for some material. 4. We would like an icon as part of the logo, possibly, although your recommendation as the designer is requested. If we DO use an icon, see the one in the logo attached and work from it. We want to make sure to create an original icon, as opposed to the stock image that was used in the past. Please try to create something that is an abstract yin/yang with a hand incorporated into the image.5. There is no corporate identity "name" persay. For print material we will just be using the text Doctor Valerian Kravtsov, Chiropractic Physician or Val Kravtsov, DC, Chiropractic Physician, so for your logo and icon presentation, if you could recommend fonts and possibly incorporate Dr. Val's title in some options and docval.com in others. 6. Ultimately, we are looking for a graphical representation of a corporate identity with limited text that can be used in various print material along with Dr. Val's name and physician title.
I may not always be able to make a personal comment on each entry soI am introducing the following rating system (thanks to moltoallegro and ysolutions)
Ratings System:
1 star - wrong direction
2 star - some elements I like
3 star - getting closer but need revisions or a different take on your design
4 star - design is being considered
5 star - made the final cut!
- A graphical representation using an abstract hand, yin yang, or valerian plant, or other natural herb (valerian root is an idea).
- Limited text. We just need font. Since there is not exact brand name, we need to be flexible on text incorporated into the "logo". We will use just the icons presented as the main logo contest winner. The text we will add on our own as needed. But please present font options that you believe work with the "icon".
- No " stick people" icons, especially with waves as part of the body, etc.
Find out how a design contest works or learn more about our logo design services.


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We've had some isolated reports this morning that myTube, one of the more popular premium YouTube apps for Windows Phone, has gone missing in the Store. With all the brouhaha between Microsoft and Google, it doesn't take too long before people start wondering if a cease and desist is the cause of the app being pulled.
No worries, fellow YouTubers. The app was deliberately hidden due a bad XAP being accidently uploaded to the Store. The developer, Christopher Blackman, reached out to us to explain the situation.
"I made a pretty terrible mistake and uploaded the wrong XAP for myTube to the Store (version 220.127.116.11). lots of functionality in the app will be missing and I've decided to hide it from the Store. The biggest missing functionality will be the background audio feature, and support for 720p screens. I've submitted another update to fix it which should be certified in a few days."
So what to do? If you haven't updated, then don't (though with the app hidden, you shouldn't be able to) and if you did, you have two options:
- Wait until the updated XAP goes through; We'll tell you and the app too will notify you when you open it (clever)
- Open the application bar menu and join the myTube beta, which is a fun thing to be a part of
So all in all, an inconvenience but no worries as myTube will be in action soon enough. Stay tuned.


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The Intercession
The Intercession of Our Most Holy Lady Theotokos and Ever-Virgin Mary (In Russian Pokrov, Покров) is a feast of the Orthodox Church. For Russian Orthodox it is one of the most important feasts and perhaps the most important after the Twelve Great Feasts. The feast day is October 1.
The origin of the feast of the Pokrov arises from the legend about the miraculous appearance in Constantinople of the Theotokos during the middle of the tenth century. The appearance occurred in the Blachernae Palace church where several of her relics were kept. The relics were her robe, veil, and part of her belt that had been transferred from Palestine during the fifth century.
In early morning of an All-Night Vigil on Sunday October 1 with an over flowing crowd of worshippers St Andrew Fool for Christ, with his disciple St Epiphanius, saw the virgin Mary walking in the air above them glowing with a heavenly light and surrounded by angels and saints. She knelt and prayed for all Christians in the world, imploring the Lord Jesus Christ to accept the prayers of all people and to respond to her intercession. After finishing her prayer of intercession she spread her veil (pokrov) over all the people praying in the church, protecting them from all their enemies.
The Russian Primary Chronicle noted that the intercession of the Theotokos was needed for the protection of the people of Constantinople when a large fleet of the pagan Rus, led by Askole and Dir, was threatening Constantinople. The invading fleet was defeated and the event remembered. Strangely, the feast came to be considered a very important feast by the Slavic Orthodox Churches but not by the Greeks.
A twelfth century Russian chronicle describes the establishment of the intercession as a special feast day honoring the event. Within a few centuries churches began being named in honor of the Protection of the Mother of God.
Among these churches two that are world famous are: in Moscow, the Cathedral of Intercession upon a Moat (In Russian: Храм Покрова "на рву," Cathedral of the Pokrov upon a moat), which is popularly known as the St. Basil's Cathedral and in Bogolyubovo near Vladimir, the Church of Intercession upon the Nerl River (In Russian: Церковь Покрова на Нерли, Tserkov Pokrova na Nerli).
The Moscow cathedral was built in the mid 1500s by Tsar Ivan IV and the Bogolyubovo church was built in 1165 by Prince Andrew Bogoliusky. In Novgorod, the Monastery of the Intercession of Our Lady (Zverin Monastery) was also built during the twelfth century.


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Black History to be celebrated Feb. 18
Holy Covenant United Holy Church, 237 Snowfield Road SE in Leland (Snowfield Community), will host a Black History celebration at 6 p.m. Saturday, Feb. 18, featuring keynote speaker Nicole Williams. The theme will be "Lift Every Voice." Local music groups will also be performing.
There will be a special missionary service at 3 p.m. Sunday, Feb. 19, with guests the Rev. Angela Collins and Price Cathedral AME Zion Church in Wilmington. For more information, call 763-2282.
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text: For more than seventy-five years the Florida Museum of Natural History has served as a repository for collections and information on the archaeology of Florida and surrounding regions, especially the southeastern United States and the Caribbean. Nearly 2,000 archaeological sites are represented in the collections (more than 1,500 in Florida). It is recommended that scholars wishing to use the collections and associated archival materials first contact the appropriate curator for information.


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Chemotherapy for Mucinous Adenocarcinoma of the Colon
Dear OncoLink "Ask the Experts,"
I was wondering what you could tell me about Mucinous Adenocarcinoma of the colon and a new treatment using CPT11-5FU-LUKOVORAN?
James P. Stevenson, MD, Assistant Professor of Medicine in the Hematology/Oncology Division of the University of Pennsylvania School of Medicine, responds:
Mucinous adenocarcinoma is a term that describes the way this colon cancer looks under a microscope. We treat it the same way as any other colon cancer. The CPT11/5-FU/leucovorin combination is now the standard front-line treatment for metastatic colon cancer. It combines drugs that have been known to be active against colon cancer. Multiple studies have shown that by combining them, better tumor response rates (about 50%) and survival of patients can be expected than when they are used alone.
The treatments are given once a week for 4 consecutive weeks followed by a 2-week break period with no treatment. These 6-week cycles can be repeated if there are signs of improvement. There are randomized trials looking at adding newer drugs to this combination, such as anti-VEGF and celecoxib that may be available in your area, and are being studied here at Penn. You might ask your oncologist if you may be eligible for any of these studies.


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A sporty girl, Cambria loves running, swimming, taking cardio classes, and strength training all while wearing a gorgeous lip gloss and sleek beach waves. She balances her love of fitness and beauty on her YouTube channel, BreeLovesBeauty, where she has videos on workout DVDs, hairstyles, free weights, and different makeup looks. The self-professed skincare lover also creates helpful tutorials on her own product regimen and how she keeps her face acne-free.
The beauty blogger shares what lip balm she literally won't go a day without using, which braided hairstyle livens up any outfit, and how to create a successful channel of your own.


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Crazy Baby Shower Cakes
These May Be the Craziest Baby Shower Cakes You'll Ever See
These May Be the Craziest Baby Shower Cakes You'll Ever See
When you think of a baby shower cake, you usually envision pink or blue with perhaps a teddy bear, stroller, or floral motif. Or at least, that's what you'd like to envision. But extreme pregnancy and new-baby-themed cakes are popping up at showers across the country, and sometimes, it's not pretty. Check out 17 cakes that we're pretty sure went just a little bit too far (including ones from Christina Aguilera and Snooki).
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On Our Radar: How to Make Your Cell Phone Battery Life Longer
UBS is moving quickly on its plan to cut 10,000 jobs and restructure operations. So fast, in fact, that scores of traders were locked out of their London offices Tuesday, according to this WSJ story. Most of the job losses are expected to come from that city, but it's still not a pleasant way to find out your job has been eliminated. — Melissa Korn
How to make your cell phone battery life last longer, even during a Sandy-related power outage, via Quartz — Rachel Silverman
We order movies using algorithms, why not conduct staffing searches that way? An argument on the Harvard Business Review blog suggests that employers are increasingly likely to find staff online, a process which, the author claims, is more efficient and less clubby. — Allison Lichter
And finally…
Must employees still be paid if their offices are closed due to the storm? AskaManager.org takes a stab at the question. — Rachel Silverman


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AnnaLynne McCord One Shoulder Dress
AnnaLynne McCord punched up a sophisticated green one-shoulder cocktail dress with a gold statement necklace and sleek ponytail. Fabulous.
Jessica Lowndes Evening Dress
Jessica Lowndes glammed it up in a summery black maxi gown with red flowers.
Browse: AnnaLynne McCord | Jessica Lowndes | One Shoulder Dress | Evening Dress
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The hubbub around URL shorteners
I never thought I'd say this with a straight face, but URL shorteners are now the topic du jour.
For those of you that have no idea what I'm talking about, a definition, from Wikipedia:
URL shortening is a technique on the World Wide Web where a provider makes a web page available under a very short URL in addition to the original address.
You've all seen the tinyurl.com addresses before, or the bit.ly addresses we use on the World Bank News Twitter stream, so URL shortening isn't anything new. What is new is the increasing attention being placed on these shorteners and their advantages and disadvantages.
Earlier this year, Joshua Schachter wrote an excellent piece citing some of the latent issues with URL shorteners, including adding levels of redirection and the possibility of link rot. The piece set off a good discussion on the value of shortening tools and best practices around URL shortening in general.
The conversation revved up recently when Google and Facebook announced their own forays into URL shortening, and bit.ly announced a new pro feature set, currently in beta, being used by organizations like the New York Times and Wall Street Journal.
All that context to say: is it time for the World Bank to invest in its own URL shortener?
With increased use of tools like Twitter at the Bank, the need for short, easy URLs is growing. How to approach fulfilling that need?
- Do we explore options like bit.ly pro and leverage their already rich suite of statistics and monitoring tools?
- Do we build our own shortener so that we don't run the risk of link rot if anything should happen to bit.ly?
- What domain should we use/acquire that is short enough but yet memorable?
- Finally, is this something we should even be looking at here at the Web Program Office?
Just a few things running through my head these past few weeks. Would appreciate any feedback you may have.


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English to polish translation jobs
As discussed via emails
500 words article. Don't bid if you are unable to complete it in next 18 hours. low budget.
have the text and possible templates just someone to plug them in and polish the slides to look good.
Hi Freelancers, We Need To Translate Our Online Product . Actually We Need Accurate And Manually Translator . Rate 0.01$ Per Words .New Freelancer Are Most Welcome
...and ios. the application is to be directed to the Polish market. the task of the application is to combine shelters for entrusting and animal owners. I want every lover of his pet to put his pet's profile in the application so that if there is a disappearance, it would be possible to compare them with animals that came to the shelter in his ...
Hello Jesus M.... Here is the project we discussed about. We will give you our project in UNITY to get started as we need someone to polish it up and make it look MUCH MORE realistic like the youtube GOPRO in the barrel waves we showed you. The mini demo game must have these elements: 1. surfboard first person view only 2. demo starts with surfboard
English to Polish translator 100 - 500 words.
...design. There need to be around 3 pages with semi-static information (text / images). The theme must be black / orange. You can work with dummie information we will add the text and images to products and static pages but we can provide all images logo's etc if needed. This will be a multi-lingual website, main language is English followed by Dutch
- Edit and polish a less than 500 word document in depth( secondary application for med school ) - Due in 1 day - A native English speaker wanted - Prefer someone with a medical background or has previous experiences with editing secondary application for med school - Expertise in creative writing, content writing, & proofreading.
...articles x 1000-1500 words each (4000-4500 words for all - acceptable). The language: Polish language The description of the articles: 1 (first) article Title: "Innowacyjność w sektorze usług zdrowotnych". No subtitles needed. The number of words: from 1000 to 1500 words is acceptable. Note: References should be included as footnotes on the same
Polish web agency needs a sales consultant to help bring clients. We are offering 8% commission on gross sales generated, for instance 100k sales= 8k commission! Naturally we are hiring a professional from Krakow, Poland because our headquaters is in Krakow. Our story is that we are a small group of marketing passionate individuals and IT geeks who
Articles about 12 biggest competitions in international football Polish texts delivered Each text 8,000 - 12,000 characters
Need a translator to convert the data from polish language to English language. We need the guy who can work at my location for a period of time
I need you to write some articles. Polishing a medical scientific paper
We are looking for a number of Polish agents with experience in Customer Services. Contractor requirements: We are looking for a contractor who: 1. Is available for 8 hours per day, Monday to Friday and Saturdays by Rotation. 2. Has worked doing Outbound sales before 3. Has to be Fluent in Polish Fluent in English. 4. Internet connection of 2Mb or
Hello! We are looking to develop a new nail-polish line and we need a full visual 3d rendering to provide to potential manufactures. We have a lot of new products in the works so we're hoping to go lower cost on this model in order to find the best suited freelancer to work with long term. We would like the nailpolish bottle to be smal...
...with good UI / UX instincts to help make improvements. It is a one page website that only sells 2 products (it is an HTML site but checkout is connected to Shopify). I also would like to add certain elements like a blog (for SEO), and embed instructional videos on the page. For this project, I would like the freelancer to submit mockups incorporating
I have a powerpoint presentation and want that to be enhanced and condensed . Below will need to be taken care of. Alignment Check Consistency Check Re-do Design Elements Adhere to Style Guide Recreate Images to Slides PowerPoint Animation Templates Icons Illustrated Graphics Infographic Conceptual Storytelling Motion Graphics Corporate Collateral
-Proofread and polish a ~600-word document ( short answers to medicine-related questions) - Due in 1 day - A native English speaker wanted - Prefer someone with a medical background - Expertise in creative writing, content writing, and proofreading.
I'm selling magic props on amazon My English is poor I hope someone can help me Polish my title, selling points and product details. I hope to be an American freelancer who has also been exposed to magic props. We can work together for a long time
...Sleeping place in apartment with kitchen and bathroom Work Clothing Materials Salary very reasonable per month according to work knowledge and speed of working. Bonus when work is done perfect and fast. Work: Mon – friday = 8 to 17h Saturday = 4 hrs cleaning Experience: We demand for experienced painters....
I need to translate 4 pages from english to polish by native speaker
I need a freelancer who can polish the transcribed [login to view URL] is a 12 minute audio, I have more than 9 minutes done. I need someone to check and complete the audio.
...someone with a sharp critical mind who loves words. That person should be experienced with different styles of poetry and be able to see the link between the message of the poetry and the extended analysis. The editor must help polish, refine and enhance the analysis ONLY. Not one comma of the poem can be changed regardless of your opinion. The total analysis
We are currently looking for a...currently looking for a Russian/Polish-speaking individual to conduct short telephone interviews with Electrophysiologists and Interventional Cardiologists on cardiac rhythm procedures. The ideal candidate will have previous experience conducting market research interviews and fluency in English, Russian and/or Polish.
Human resource - Find a team of 3 Polish, Romanian or Ukrainian Solar PV installers To install on +- 60 locations in Belgium small PV installs. Job starts immediate and end at 20 december 2018.
I have three Formulas A, B, C, that need to be written mathematically, and possibly write an algorithm to go with it. % PREPOSITIONS % COMMON NOUNS % PLURAL NOUNS % BASE VERBS % DETERMINERS % ADVERBS % PRONOUNS % ADJECTIVES The % is defined, but not in above example, since this post is public to freelancer.com. What I Need is mathematical formula
We are looking for a dedicated indivual. Someone who can: - scrub footage - find the best B-roll from hours of footage - rough cut videos together - polish, and colour grade - top and tail - add effects, designs and transitions - balance and edit audio Adobe Premier Experience a must. Must be conversant with the whole Adobe Creative cloud suite
I need a male polish vioce over / lektor
We are Polish start-up who created the first-ever Evacuation Management System which based on RFID technology. To learn more about EMS, please look here: [login to view URL] We need an animator, who would make a clear yet interesting and eye-catching animation that would present "how does it work" and engage viewer to contact
...musical videos and are broadcasted worldwide. The job will be to translate the lyrics from English to one of the foreign language listed below and provide a singing voice in the same foreign language. To give you an idea of what kind of lyrics need to be translated and how the English singing voice sounds, you can take a look at the episodes we'v...
...for a person to call all 150 companies, introduce my company and after that, ask for a meeting. After they agree on a meeting, put everything in one nice schedule according to location of companies so that it would make sense for me to go through all of them by a car. Polish should be used for calling companies in Poland. When it comes to Czech and Slovakia
This is an article I wrote, to recount a personal experience of mine and since I'm a non native speaker I'd like an experienced proofreader to polish the text and make it more suited to a mainstream north-american publication like Vice or Medium. I am attaching a text sample.
I need a text to be translated from English to Polish by a native speaker. I would like to hire someone, who I can work with in the long term, since I have texts for translations every month.
Media Kit for the movie festival, seeking a designer to polish the written power point, require Chinese/Film/Australia elements.
Hi there, I have an English document to be translated into Polish. Professionals as well as freshers are welcomed to. Native to Polish language are proffered. Only bid if you can do it. Best Regards, Navalli.
Hi there, I would like to proofread and edit my word document. Polish native speakers only. Please send me your rates. Thank you.
Swarms Agency is excited to bring you on board as Sales Specialists. We're just a few formalities away from getting down to work. Please take your time to review offer. It includes important details about your compensation, benefits and the terms and conditions of your anticipated employment with Swarms agency. Swarms Agency is offering a B2B position
we have 2 wp installations ruining on s...2 wp installations ruining on same server which are very low in words and looking for someone to translate admin backed and front end and add a language selector on both installations on front end and backedn no google trasnlations need a proper translation with good 3rd part company or similar. NO TIMEWASTERS
I have some English tech-scripts that is needed to translate into Portuguese & Polish. They are about e-commerce sites that involves native Portuguese & Polish idioms. There are about 5000 words in it. I wanna hire native speakers who have general tech-knowledge about web. Thanks and cheer!
...exploratorily and focus on the functionality. The purpose of this contest is for us to try out the concept of letting freelancers help with the bug hunt. The freelancer who can find and present the most errors in the best way will be chosen as the winner. In addition to this contest we are looking for several freelancers who can help us searching error
I have a small security device that I am taking to market. I have a written a press release but I would like to have someone proof read it for me before I send it out. Possibly add some polish to it as well.
...research as possible, for e.g I found an English list that has more than 370k words, while the Oxford dictionary has only about 171k I prefer the 370k words in this case, as I said the more the better. The languages: English Chinese Danish Dutch Swedish French German Hindi Icelandic Italian Korean Norwegian Polish Portuguese Romanian Russian Spanish Turkish
We're looking to hire an independent contractor to assist a relocating associate in Irvine, CA. The associate is authorized for one day of assistance.
I am looking for a Polish native speaker who can write 15-20 pages on Management and Innovation in Polish language. Prior knowledge of Academic, assignment writing and referencing styles is essential. This will be a one-time project and I would need it as soon as possible. Let me know your rate and I will give you more details on the topic of this
...hiring a ghostwriter to create posts for my blog. The blog is about search funds, a niche private equity model for entrepreneurial buyouts of SMEs. I would like to start out by paying for two blog posts immediately - $60 total for the 2 posts. If all goes well, I'll need 4-8 posts per month on an ongoing basis. I will ask you to write posts on topics
I am looking for a native Polish speaker who will translate a hand book from German to Polish (~1500 words in total). I am especially looking for SMART translation done by a real human - meaning the translator should take the context and the audience into consideration. Best, FW
I have several articles that need to be proofread, priority will be given to the native Polish freelancers.
I have written a marketing plan, I need it organized and edited by a very qualified professional!
...webshop has a Gel polish brand called CCO. Attached you will see the 15 ml bottle. It has fresh, modern, minimal style. Now we are starting to sell the same brand 5 ml version. The bottle is simple and black, thats why I need somebody, who are planing a cool label for that bottle. I will need a vector format and 30 colour versions according to the colour of


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We require a set of inspections for all permits to confirm various steps in the construction and installation process. Find out what's required and when to schedule each type:
You can schedule most inspections by:
Annual inspections for boilers and elevators or escalators and inspections for code compliance and design review are scheduled automatically; special inspections require that you select an inspection agency and arrange site visits with them.
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Using computer simulations to predict which drug candidates offer the greatest potential has thus far not been very reliable, because both small drug-like molecules and the amino acids of proteins vary so much in their chemistry. Uppsala researchers have now cunningly managed to develop a method that has proven to be precise, reliable and general.
The largest class of human target proteins for drugs are the so-called G-protein-coupled receptors. They are targets for about 40 per cent of all drugs on the market. These receptors are found in the cell membrane and handle the communication between the outside and the inside. When they react to external stimuli, by binding molecules, for example, a structural transformation takes place on the inside that triggers a signalling cascade (see 2012 Nobel Prize in Chemistry).
- In this way these receptors regulate our senses of smell, taste and vision as well as a number of other conditions and feelings, explains Professor Johan Åqvist, who directed the study, which is now being published in the prestigious journal PLOS Computational Biology.
Of the roughly 900 G-linked-protein receptors in humans, today we know the three-dimensional molecular structure of only about twenty. It is important to know this molecular structure when drugs are developed.
The method used today to understand how the receptors function is complicated and time-consuming. First the binding strength of series of molecules is measured (the binding of so-called agonists and antagonists). Then mutations are induced in the receptors in order to see how the binding properties are affected.
- This is both time-consuming and often difficult, because the genetically modified receptors have to be expressed in living cells. With our computational method, the mutation can be created in the computer, and the effect on receptor binding can be calculated with great precision, says Johan Åqvist.
The problem with this type of computer simulation has previously been that the amino acids of the proteins are so different, in terms of size, electrical charge, etc., which has presented problems in the calculations. But when the researchers divided the procedure into a long series of smaller computations, something happened - suddenly they were getting exact and stable results.
The method has now been tested on a neuropeptide receptor and has been shown to be able to predict with great reliability both the effects of mutations and the receptor's ability to bind a series of different molecules. The method also makes it possible to determine whether a three-dimensional structural model of the molecules that are bound to each other is correct.
- The results are brilliant. We believe this has the potential to be extremely useful in drug research. It quite simply makes it easier and faster to find candidates for new drugs. The computational method is also so general that it can be used to study all sorts of other proteins bound to various types of functional molecules, says Johan Åqvist.
Article: Lars Boukharta, Hugo Gutiérrez-de-Terán, Johan Åqvist: Computational Prediction of Alanine Scanning and Ligand Binding Energetics in G-Protein Coupled Receptors. PLOS Computational Biology, Published: April 17, 2014. DOI: 10.1371/journal.pcbi.1003585


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Selectable vs. Automatic - The Differential ShowdownPosted in How To: Transmission Drivetrain on July 3, 2013
Installing a locking differential into your 4x4 is one of the best upgrades you can do. Understanding that a locker is what allows your wheels to spin at the same speed (no more one-wheel-peel), installing one (or two) in your rig can boost its off-road performance tremendously. Getting the right type of locker for your rig is just as important. For the sake of this argument, we've split the locker debate into two camps: selectable and automatic.
An automatic locker is one that automatically engages (locks) when power (throttle) is applied, whereas a selectable locker requires additional input to engage (with the pull of a cable or push of a button, generally). While the end goal is the same for both, how they affect the handling and performance of your 4x4 on- and off-road can be very different. Senior Editor Brubaker is hedging his bets that the selectable locker is the logical decision for the modern rig in need. Technical Editor Mansour is holding ground that the no-frills automatic locker is the one to have. So which side will have you engaged?
Selectable Locker: You're in Control
There are times when I want a locked axle, and there are times when I do not. For example, when plowing snow in tight quarters or off-camber an unlocked axle lessens the chance of side-to-side movement that could cause my rig to slide into a building, another vehicle, or down a slope. The same goes for slick surfaces like ice and mud. With the axle unlocked, the tires tend to stay more laterally planted in off-camber and pushing/pulling situations.
But there are also times when I need a locker. For example, when I mess up and get my plow rig stuck, my rig is twisted up and one wheel of my 4x4 is in the air, or when I need the most traction to climb an obstacle. In these situations sending power to both wheels on an axle is the key to continuing forward progress.
A selectable locker gives you even more control over how your 4x4 reacts and behaves.
It's for these reasons that I'm a fan of selectable lockers. I've had a number of automatic lockers in my rigs over the years and they work great in most situations, but I prefer to decide when power is going to both wheels on an axle and when it is not. Additionally, after over two decades of wheeling I've found that in most situations my rig just doesn't need full-time lockers and open diffs work just fine for most wheeling, working, and inclement weather.
I'll admit that automatic lockers are generally less expensive than selectable lockers and they install far easier because they are self-contained. Selectable lockers are a bit more labor intensive to install, depending on which kind you choose. The ARB Air Locker requires the installation of an air source like a compressor (you needed a compressor on your rig anyway, right?), as well as other items such as air lines, wiring, and actuator button. An electrically-actuated locker like the Eaton E-Locker requires tapping into a power source and installing wiring and an actuator button. The Ox Locker, on the other hand, allows manual engagement of the locker via a cable. Most selectable lockers also require drilling a hole in the axle centersection or diff cover to run wiring, an air line, or a cable to the locker mechanism.
Another benefit of a selectable locker is that because it can be disengaged, it can be installed in a front axle, where you normally wouldn't want a fulltime locker due to adverse handling. When unlocked, it will be transparent, with no negative effect on steering or handling, but when locked you get power to both wheels. Another bonus of a selectable locker is that it will not be locking and unlocking automatically, which wears parts like clutches and gears.
Summary: A selectable locker allows you to choose exactly when power is distributed to both wheels on an axle. A selectable locker gives you even more control over how your 4x4 reacts and behaves.
–Ken Brubaker
Automatic Locker: Don't Think, Just Do
I'm a frugal enthusiast, or as my wife says, cheap. When I first got into wheeling, I couldn't afford the biggest and the best, so most of my upgrades were based around cost and performance. Seeing that selectable lockers were more expensive than automatic lockers, auto is what I opted for. Over the years, I have been fortunate to use both auto and selectable. While I will admit that selectable lockers are nice to have on the street, I am still more likely to champion the auto locker—especially full-carrier replacement types such as the Detroit Locker.
Automatic lockers are no-nonsense traction aids that are designed with strength and simplicity in mind.
With that being said, I will be the first to admit that I am terrible at compromise. I have found that I do much better with having a purpose-built trail rig, rather than a dual-purpose rig that also has to work as my daily driver. This means I am more tolerant of handling quirks and noises that automatic lockers sometimes deliver on the street. Similar to a new steering setup or an aggressive set of mud-terrains, your rig will act different with automatic lockers. The good news is that in most cases the strength and simplicity of the auto locker is well worth the minor on-road handling gaffes.
The worst handling characteristics are usually most prevalent in short-wheelbase vehicles like the Suzuki Samurai and Jeep Wrangler. Those short-wheelbase rigs equipped with manual transmissions can aggravate the situation. Longer wheelbase 4x4s and those equipped with automatic transmissions will find the automatic lockers much less invasive. Unlike selectable lockers where you have to worry about air compressors, plumbing lines, and additional components failing, the automatic locker is a self-contained device. There is no switch to activate, no knob to turn. The automatic locker is like your own traction mercenary. It only needs a little input from your skinny pedal and it will do exactly as you want.
Another advantage of the automatic locker is there are entry level versions that are extremely installer and budget friendly. These are often referred to as lunch-box or drop-in lockers as they fit inside of your open differential carrier and take place of the stock spider gears. These types of lockers allow virtually any shade-tree mechanic with a basic tool set and understanding of the axle at hand the ability to install a locker. Oh, and for just about the same cost as one selectable locker, you can have two automatic lockers. How's that for savings?
Steering is another area where people have a misconception that the automatic locker is bad. Yes, when not engaged, a selectable locker is easier to steer and places less strain on driveline parts. The trouble is when you engage a selectable locker it becomes, in essence, a spool. This spool will not allow any give between the tires. Although this makes the locker very strong, it also can make steering extremely difficult. The automatic locker on the other hand, will actually allow give and/or slight differentiation between the tires rotation. This makes steering much easier compared to an engaged selectable locker.
Summary: Automatic lockers are no-nonsense traction aids that are designed with strength and simplicity in mind. If your 4x4 is a dedicated trail rig, then the automatic locker absolutely makes the most sense. Sure, there are on-road handling quirks, but nothing that you can't live with. When it comes to bang for your buck, it's hard to beat an automatic locker.
–Ali Mansour


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City to pay people to get tested for HIVBy KIMBERLY HOUGHTON
Union Leader Correspondent
June 26. 2013 10:33PM
NASHUA - As part of National HIV Testing Day, $10 gift cards will be offered today to anyone who is tested for the disease at two different sites in the city."We will be handing out $10 gift cards for Walmart or Market Basket. This is the first year we are really making a big campaign out of this," said Christine Villeneuve, nurse manager for the city's Division of Public Health and Community Services.Anyone interested in being tested for HIV is encouraged to visit the city's mobile outreach van from 11 a.m. to 2 p.m. today at 28 Railroad Square, the Laton House.
Testing will also take place from 3 to 9 p.m. at the city's health department, 18 Mulberry St.All testing is free of charge, according to Villeneuve, who said the procedure takes about 20 minutes. Including registration, however, the entire process could be about 45 minutes.
"Hopefully we can reach somebody that needs our help," she said.Today's initiative is part of the Centers for Disease Control and Prevention's Know Your Status campaign.
For more information, call 589-4500.
In addition to this one-time free HIV testing event, the city's Division of Public Health and Community Services conducts weekly STD/HIV clinics from 3 to 6 p.m. each email@example.com


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BERLIN (AP) — Ground staff at Lufthansa, Germany's biggest airline, are staging a several-hour strike that has prompted the company to cancel hundreds of flights.
The ver.di union called workers at several airports including Frankfurt and Munich out on a so-called warning strike ahead of wage negotiations. The walkouts started Thursday at 4 a.m. (0300 GMT; 11 p.m. Wednesday EDT) and are to continue until late morning.
Ahead of the strikes, Lufthansa canceled nearly 700 flights — including much of the morning's domestic and European flight schedule.
The union and Lufthansa are to meet Friday to discuss ver.di's demand for a 5.2 percent increase over the next year for 33,000 Lufthansa employees. Ver.di says Lufthansa's call for a two-year pay freeze until January 2015 and the extension of the work week by an hour is unacceptable.


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By MARCY GORDON
AP Business Writer
WASHINGTON (AP) — JPMorgan Chase CEO Jamie Dimon says the bank did its best to fully inform investors about its risk strategy several weeks before it suffered a $2 billion-plus trading loss.
Dimon told the House Financial Services Committee Tuesday that the bank trusted its methods for assessing risk and that the models used provided the best information at the time. The risk models are frequently updated, he said.
"We disclosed what we knew when we knew it," Dimon told the panel.
The Securities and Exchange Commission is examining whether JPMorgan's earnings report on April 13 gave adequate information on the risk model the bank was using.
Earlier at the hearing, SEC Chairman Mary Schapiro told the panel "there could be" violations that would merit legal sanctions against the bank.


text: George Moses Horton (ca. 1797-ca. 1883) was born the property of William Horton, who owned a plantation in Northampton County, NC, but subsequently moved to Chatham County, NC. At William Horton's death in 1814, George became the property of William's son James; at James' death in 1843, James' son Hall inherited George. As a child, Horton "taught himself to read and began composing in his head a series of stanzas based on the rhythms in Wesley hymns" (Dictionary of North Carolina Biography 3:207). By the time he was twenty, he was walking to Chapel Hill on Sundays to peddle fruit. Horton composed poems for students, selling them for twenty-five to seventy-five cents and becoming well known for acrostics on the names of students' sweethearts. For several decades Horton was able to buy his time from his master with the money he earned from students and by working as a campus laborer. Students loaned him books, and Caroline Lee Hentz, novelist and wife of modern languages professor Nicholas Hentz, helped him publish his first poems in newspapers. With her encouragement Horton published in 1829 The Hope of Liberty, the first book published in the South by an African-American. Horton intended to use the proceeds to buy his freedom and move to Liberia, but when the profits were inconsiderable, Horton's own "hope of liberty" was dashed. In 1845 The Poetical Works of George M. Horton, The Colored Bard of North-Carolina, To which Is Prefixed The Life of the Author appeared. At the close of the Civil War, Horton left Chapel Hill, following a Michigan cavalry unit, and with the help of Captain Will H. S. Banks published his third book Naked Genius (1865). Horton spent the last eighteen years of his life in Philadelphia. He married a slave of Franklin Snipes and fathered a son and a daughter, both of whom retained their mother's name (Dictionary of North Carolina Biography 3:207).


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In 1960, Mr. and Mrs. Vernon Coulter, members of the Willisburg Christian Church, donated 26 acres of land to be used as a spiritual camp for kids. The first group of 86 campers arrived in the summer of 1963 and learned about the teachings of Jesus Christ. Since those early days, the camp has expanded to more than 400 acres. Dormitories, meeting halls and a covered pavilion have been built. Last year, more than 1,200 campers attended events at Camp Calvary.
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McMichael High School principal hurt in head-on crash
McMichael High School principal hurt in head-on crash
A high school principal is recovering after being hurt in a head-on crash while driving to work.
Leigh Jones, 39, was injured in the crash around 7:15 a.m. Friday on U.S. 220 just north of U.S. 158.
Jones has been the principal of McMichael High School since August 2011 and was named Rockingham County Schools principal of the year in 2012.
Counseling will be made available at McMichael on Monday, RCS officials said. School officials notified McMichael parents by phone on Saturday.
RCS officials didn't release any details about the crash, saying the highway patrol is investigating. Immediate attempts to reach investigators weren't successful.


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Living Big and Writing the Same Way
Last year at this time, if you read this blog, you knew all about Tough Mudder, because I ran it. For those who don't know, Tough Mudder likes to bill itself as probably the toughest event on the planet. The people who run Tough Mudder have obviously never rooted for the Jets on a nationally telecast football game, but it's still pretty tough.
Tough Mudder is an eight-to-twelve mile cross-country run with some obstacles built in. You know, little things like a dumpster filled to chest level with ice water, and a matrix of wires you run through–some of which are live. If you live in a place with mountains, you run up and down a ski area. Otherwise, you run through a huge amount of mud.
Unless something horrible happened, I completed this year's Tough Mudder over the weekend. Been there, done that, got the t-shirt. (Literally, you get a t-shirt and the best-tasting beer you've ever had when you cross the finish line.) If Ernest Hemingway were to run an extreme event, this might be it. Then again, he might just shoot someone and decide it was enough.
The point of this post isn't to convince you to run Tough Mudder. It's to convince you that as a writer, it's part of the job requirement to suck the marrow out of your life. Experience it for all you're worth, both good and bad. Then take those experiences and write about them.
As someone who has been excessively risk-averse through most of my adult life, I believe my writing has only blossomed since I stopped being so worried about what might happen. In taking more chances in life, I've also starting taking more chances in my writing. We're not talking about running around with a metal pole in a thunderstorm. Or going to Texas wearing a t-shirt that says "Texas is for Sissies."
We're talking about being bold and challenging yourself, doing something uncomfortable, just so you can see how it turned out. Maybe it's writing a different genre, a different point of view, or writing about something that's close to your own areas of vulnerability.
It's about living big and writing the same way.
In less than a month, it's going to be time for the dreaded New Year's Resolutions. That gives you a few weeks to really think about your writing life, and consider what you might challenge yourself to do in 2013 that will push you to the next level.
Get thinking, because there will be a test.
January 8, 2013 11:54 am
Read about this in The Palm Beach Post. Some people (Seminarians from Boynton Beach) participated in it. Until then, hadn't heard about the event.
A bigggg Bravo! for you.
Comments are closed.


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Senior Lighting Designer
- Recruiter
- Mindseye Architectural Lighting Design
- Location
- London
- Salary
- Competitive Salary
- Posted
- 09 Jan 2013
- Closes
- 06 Feb 2013
- Sector
- Architecture, Lighting
- Function
- Design
- Job Type
- Permanent
Mindseye is recruiting a senior project lighting designer. It's an opportunity to run projects with a high degree of autonomous creative control, whilst having excellent support from dedicated and passionate junior designers, as well as an excellent in house project manager, and an Associate and a Director each with their own well established reputation for design excellence. Mindseye breaks boundaries, always challenging the definitions of what a lighting design team can provide.
Mindseye combines a rigorous and uncompromising approach to design with a practical attitude towards reliability and maintenance, all underpinned with exacting attention to detail.
If you are interested in joining our small busy team, and you can demonstrate breadth and depth of creative and technical ability, we are interested in hearing from you. You will have three to four years of experience with a solid background in project based lighting design. Excellent AutoCAD, AdobeCS, Dialux are essential, as well as Microsoft Office. You will also be expected to demonstrate excellent visual and verbal communication skills, an organised approach, and commercial acuity.
We do not accept applicants from recruitment agencies, so if you would like to apply, please do so directly.
Please apply in writing with CV to:
Daniel LaDuc


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This from press release sent by Starting Point with Soledad O'Brien:
After winning the Florida primary, GOP presidential nominee hopeful Mitt Romney explains to CNN anchor Soledad O'Brien that he is focused on a particular portion of the American population in his campaign.
Romney says, "I'm not concerned about the very poor. We have a safety net there. If it needs a repair , I'll fix it. I'm not concerned about the very rich.... I'm concerned about the very heart of America, the 90-95 percent of Americans who right now are struggling."
O'Brien asked him to clarify his remarks saying, "There are lots of very poor Americans who are struggling who would say, 'That sounds odd.'"
Romney continues, "We will hear from the Democrat party, the plight of the poor.... You can focus on the very poor, that's not my focus.... The middle income Americans, they're the folks that are really struggling right now and they need someone that can help get this economy going for them."
Starting Point with Soledad O'Brien airs week mornings from 7-9am ET on CNN.


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HSAM2000 - Health Care Law and Ethics
Fall 2012
This course will familiarize students with the basic concepts of law as formal social constraint and ethics as informal social mores as they relate to the delivery of health care. Health care law will track the growing right to privacy as developed and applied by the U.S. Supreme Court in cases involving contraception and abortion, the right to refuse treatment, the right to withhold treatment and the right to die. Health care ethics will address questions regarding non-legal but essential societal decisions regarding who gets care and how and the right of health care professionals to refuse to treat. Ethical and legal questions in the area of informed consent, privacy of information and access to information will also be covered.
3 Credits
Schedule Book for All Active and Available Future Terms, Course starting with HSAM2000
No Courses Found


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By ,
Published January 13, 2015
A Utah judge denied bond to a young father accused of plotting for a month before killing his infant son with a rifle.
Joshua Petersen, of American Fork, will stay locked up until formal charges are filed Friday.
Utah County prosecutor Craig Johnson says a police sergeant testified Monday that the 21-year-old planned for a month to shoot his 5-month-old son and did so last Friday.
Johnson tells The Associated Press the motive for the shooting at a home is unclear.
Family members tell Utah news outlets that Petersen was suffering from depression and the recent breakup of his relationship with the boy's mother.
Police say Petersen sought to turn the gun on himself after killing his son but was stopped by a family member.


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She'sTheFastest wrote:DudeMan2766 wrote:Powerslam, super plex, middle rope DDT that Punk escapes, middle rope DDT that Orton hits, missed RKO followed by an RKO that connects. Either that or Orton hits someone with an RKO after the match
Bret Hart NEVER changed it up either.
But that was back when I was like 8 and wrestling was real so that stuff didnt both me lol


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You look like you could use a good old fashioned 20% off. Code: SPACE20
The first chopper bicycle was on sale in 1969.
bike chopper bikes cycle cycling bicycle bicycles fixie fixed gear vintage retro racing race old messenger amsterdam love cool grunge vector raleigh schwinn wheels frame red suburbain fence grass garage america american 1969
Nice one! I seen some images on Fubiz of bikes the other day that looked like your illustrations. Were they yours?
heres the link https://www.facebook.com/photo.php?fbid=1015155...
Thanks for your comments, no those ones arn't mine but very similar. Thanks for the link!
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The Clifton Historical Museum is a worthy tribute to the district's pioneering past. Housed in the old butter factory, you can take a step back in time and visit a 1930s dining room, a pioneer bedroom, an early hospital ward, kitchen and children's room.
The Heritage room allows access to original records of local businesses and schools. Read the memoirs of long-time residents, browse through the photographic collection, or look for your forebears on the database.
An extensive range of early agricultural tools and machinery will evoke memories of yesteryear.
Old movie memorabilia, communication, history, musical pieces; there's something for everyone, discover it for yourself.
Note: Information on listed products and services are provided by the operator and were correct at the time of publishing. Rates are indicative based on the minimum and maximum available prices of products and services. Please visit the operator's website for further information. All prices quoted are in Australian dollars (AUD).


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Pablo Schreiber is very good at being bad. The Tony nominee for "Awake and Sing!" and half brother of Liev Schreiber is compelling and repelling viewers on Netflix's hit "Orange Is the New Black." Schreiber plays prison guard George "Pornstache" Mendez—so named for his John Holmeseque facial hair, who thinks nothing of copping a feel from the female inmates. He will also return to "Law and Order: Special Victims Unit" Sept. 25 as rapist William Lewis to wrap up last season's cliffhanger. And while his future on "Orange" is uncertain—they're currently filming the second season but nothing has been confirmed regarding his return—he starts a new series in the fall with the premiere of the rebooted "Ironside." Backstage spoke to Schreiber about finding the heart of a villain and the surprise success of "Orange."
Embrace the love. And the hate.
Schreiber is enjoying portraying the controversial Pornstache, even though some viewers despise his character. Say people are in love his performance and he corrects, "They're madly in love-slash-hate. Which is just as I would have it." He relishes the opportunity to play someone so awful, noting, "What a great freedom to be given the gift of having zero filter and no inhibitions." He admits that the success of the show, which has beaten properties like "House of Cards" and "Arrested Development" for views, has caught everyone off guard. "I think part of that is the element of discovery. Because there's no major brand names associated with it, other than maybe Jenji [Kohan, the creator]. So I think people had a real sense of discovery. How many wonderful actresses are there in that show that you've never heard of and just knock your socks off?"
Take a leap of faith.
Schreiber signed on to play Pornstache having only read the pilot script, in which the character makes a brief appearance as he checks in new inmates. "There wasn't much of a character yet," he admits. "I had no idea what was in store." He had previously worked with Kohan on "Weeds" and says she "is a person I would follow anywhere." He also had a friend in the writer's room who tipped him off that there would be fun stuff for the part. "But I didn't know what it would entail or become," he says. "I think three or four episodes in, I started to sense something, just by the reactions on set and how much the crew was enjoying the character."
Find the humanity. And the facial hair.
In his review of Neil LaBute's play "Reasons to Be Pretty," New York Times critic Ben Brantley said Schreiber "confirms his great gift for making unsympathetic characters not just believable but also understandable." This was after Schreiber had played twins in "Dying City," one of which was an angry actor who lashed out at others. Says Schreiber, "If there is a reason I'm able to make unsympathetic characters human it's because it's my desire to find what drives the unsympathetic behavior. Almost always at the bottom of it is some deep insecurity. Putting your finger on what each individual's particular insecurity is goes a long way to fleshing that person out." Also helping is just the right facial hair—his character in "Pretty" sported a pathetic goatee that he says "really helps communicate you're playing a douchebag." And believe it or not, the moustache he sports on "Orange Is the New Black" is not his own. Calling his upper lip "folliclely challenged," he says the moustache was key to the role. "The role was an offer, but they did bring me in to try on moustaches," Schreiber admits. "I was very eager to find the right look. I wanted him to have a flattop like Dolph Lundgren so I brought in a picture of him from 'Rocky IV' and we did our best to imitate that style. "
Play nice.
Schreiber will get a chance to "get a little closer back to myself and play a good guy" with "Ironside," premiering Oct. 2 on NBC. The reboot of the Raymond Burr classic finds Blair Underwood as a cop, paralyzed in the line of duty, who puts together a special task force of officers. Schreiber plays Virgil Burke, who he says has a history of violent sanctions, but lives in the suburbs with his family. "He's trying to balance the violent nature of the job and how much he actually likes it with being a family guy at home," he says. "There's still some darkness there, but at least he works for the right team." And what kind of facial hair will be sporting on the series? Schreiber laughs. "There will be no facial hair in this one! I am completely clean shaven!"


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Wednesday, August 21, 2013
Parc de Bagatelle
26 comments:
The deep pink, almost red dahlias are wonderful also. Thanks for the garden tour. Can't wait to hear more about cheese.ReplyDelete
I have some of those Phlox in white and pink ones, compliments of my neighbor thinning hers out. :) I love this post. What a wonderful place to go visit. I hope to see the Lily ponds and you need to go back next June for the Roses. Oh and that Peacock...would I love to have it bothering me. Your Rose painting and its colors looks like an old fashion painting. Love it.. Fab post.ReplyDelete
They are indeed phlox blooming along my pink ones also right now in QC.ReplyDelete
What glorious gardens..Your rose paintings are expressive and unique..
I would love a peacock sighting!!
The white flowers are Phlox they have a scent and bloom in last part of summer till fall usually. They come in other colors and they return each year. I love themReplyDelete
I always enjoy the Bagatelle when I get the chance to go there. Love that little bijoux of a building.Looks like you had a lovely day!Replies
I wonder how crowded it gets, this being August it was quiet.Delete
A wonderful place to return to many times
I can't wait to see more of your trip to Bagatelle, Carol. Lovely. On another note, is this where the Duke + Duchess of Windsor lived at one time? xoReplyDelete
Yes, Villa Windsor. Diana and Dodi visited it for 30 minutes the day they died. His dad was renovating the villa at the time. The contents of the house were later auctioned off. Mind-boggling, the history of this incredible park.ReplyDelete
Some of those arbors look like wisteria....worth a springtime visit just to inhale the scent.ReplyDelete
So beautifulReplyDelete
- Anonymous2:22 AM
My God these gardens were just breath taking.. Your blood pressure must have been at its lowest...ReplyDelete
It"s low tobrgin with so...Delete
Thanks for this post. I tried to tour the Chateau de Bagatelle last October on a rainy Sunday at 3pm (at that time, the only time available for tours), but the guide never showed. Also thanks for the directions on how you arrived there. I am familiar with the past history of the Chateau de Bagatelle -- now must investigate Villa Windsor.ReplyDelete
Green with envy!ReplyDelete


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David D. Nolte
ORCID(not set)
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BiographyProf. David D. Nolte is a professor of Physics at Purdue University. His research interests range over broad aspects of interferometry and holography, and he has written "Optical Interferometry for Biology and Medicine", published by Springer in 2011. His current research is on a high-speed biosensor known as the BioCD, and on motility contrast imaging of live tissue. He is a Fellow of the Optical Society of America and a Fellow of the American Physical Society. He was a Research Fellow of the Alfred P. Sloan Foundation, and a Presidential Young Investigator of the National Science Foundation. In 2005 he received the Herbert Newby McCoy Award, the highest scientific honor awarded by Purdue University. He received his baccalaureate from Cornell University in 1981 and his PhD from the University of California at Berkeley in 1988 in solid state physics, followed by a one-year post-doctoral appointment at AT&T Bell Labs before joining the faculty at Purdue. He is a technical founder of Perfinity Biosciences, a small biotech start-up company providing proteomic technology solutions, and has recently launched a new start-up company, Animated Dynamics, to pursue applications of motility contrast imaging in the pharmaceutical industry.


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Volunteer drivers needed in Windham
WINDHAM — The departure of Cooperative Alliance for Regional Transportation's (CART) services from the Windham region has left a growing void for the elderly who had previously relied on its affordable bus trips to get them to medical appointments and the grocery store.
In an attempt to cut $13,000 in town spending, the Windham Board of Selectmen voted last January to withdraw from the Derry-based agency that once filled that need.
At the time, then board chairman Bruce Breton said Windham could do without CART's services since the town already allows its residents to schedule rides in the municipal van.
But despite the services offered by the town, the staff of a nearby nonprofit said there are still plenty of Windham residents who have been asking for help lately.
"Right now we're seeing a definite increase in the need for transportation services," Cindee Tanuma, executive director of Community Caregivers of Greater Derry. "So we're currently filling that need almost entirely by drivers in surrounding towns.
Tanuma said the local nonprofit, which will celebrate its 25th anniversary later this year, is hoping some Windham volunteers might step forward to help out.
"If you have two days a month to drive a fellow community member to a local appointment, we want to hear from you," Tanuma said, noting that a common misconception about volunteering is that it's more of a commitment than it really is.
"For every new driver, we can help three new members from the community," she said.
Organization officials said the majority of rides given would be within a 10-mile radius, though occasionally some volunteers might be asked to drive clients to other nearby Massachusetts or southern N.H. towns.
Finding dependable volunteers is a constant struggle for the Caregivers, according to Tanuma, who noted that outreach efforts typically take place during town fairs and other public events.
Staffed almost entirely by volunteers, Community Caregivers assists the elderly and disabled with services such as friendly visiting, grocery shopping, light chores, home repair and maintenance, and medical transportation, with all services provided at no cost to the clients.
"Services offered through Caregivers are vitally important as they allow individuals to maintain independence in the community and home environment," Tanuma said. "The idea is to encourage citizens to help others within their own neighborhoods and communities.
Volunteer training will take place in early June. For more information on current volunteer opportunities, visit www.comcaregivers.org or call Tanuma at 432-9877.