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TOLEDO, OH (WTOL) - Beginning Sunday, December 26, 2010, routes 17, 19, 22, and 32 have had modifications reflected in their weekday times.
Also, TARTA's agreement for the St. Joseph Park-N-Ride location expires at the end of 2010, Centennial Terrace will remain a Park-N-Ride, Muddy™ Shuttle, and Walleye™ Shuttle location in the City of Sylvania.
Lastly, Routes serving The University of Toledo Health Science Campus no longer make stops on Library Circle.
Get complete details of route changes on the TARTA news page.
Copyright 2010 WTOL. All Rights Reserved.


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subset: commoncrawl


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Estate agents in GU33
1 - 1 of 1
List Map
Hamptons International - Alton
31 High Street, Alton, GU34 1AW - We also cover GU33
With over 140 years experience in selling and letting property, Hamptons International has a network of over 85 branches across the country and internationally, marketing a huge variety of ... more
Residential for sale: 72
Avg. asking price: £692,734
Avg. sale listing age: 26 weeks


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Total Has Entered Exclusive Talks Alongside EDF Related To Sale Of Stake In Dunkerque LNG Terminal
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Work could eventually lead to cell transplants for people blinded by glaucoma, MS
Johns Hopkins researchers have developed a method to efficiently turn human stem cells into retinal ganglion cells, the type of nerve cells located within the retina that transmit visual signals from the eye to the brain. Death and dysfunction of these cells cause vision loss in conditions like glaucoma and multiple sclerosis.
"Our work could lead not only to a better understanding of the biology of the optic nerve, but also to a cell-based human model that could be used to discover drugs that stop or treat blinding conditions," says study leader Donald Zack, M.D., Ph.D., the Guerrieri Family Professor of Ophthalmology at the Johns Hopkins University School of Medicine. "And, eventually it could lead to the development of cell transplant therapies that restore vision in patients with glaucoma and MS."
The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.
Using a genome editing laboratory tool called CRISPR-Cas9, investigators inserted a fluorescent protein gene into the stem cells' DNA. This red fluorescent protein would be expressed only if another gene was also expressed, a gene named BRN3B (POU4F2). BRN3B is expressed by mature retinal ganglion cells, so once a cell differentiated into a retinal ganglion cell, it would appear red under a microscope.
Next, they used a technique called fluorescence-activated cell sorting to separate out the newly differentiated retinal ganglion cells from a mixture of different cells into a highly purified cell population for study. The cells showed biological and physical properties seen in retinal ganglion cells produced naturally, says Zack.
Researchers also found that adding a naturally occurring plant chemical called forskolin on the first day of the process helped improve the cells' efficiency of becoming retinal ganglion cells. The researchers caution that forskolin, which is also widely available as a weight loss and muscle building supplement and is touted as an herbal treatment for a variety of disorders, is not scientifically proven safe or effective for treatment or prevention of blindness or any other disorder.
"By the 30th day of culture, there were obvious clumps of fluorescent cells visible under the microscope," says lead author Valentin Sluch, Ph.D., a former Johns Hopkins biochemistry, cellular and molecular biology student and now a postdoctoral scholar working at Novartis, a pharmaceutical company. Sluch completed this research at Johns Hopkins before transitioning to Novartis.
"I was very excited when it first worked," Sluch says. "I just jumped up from the microscope and ran [to get a colleague]. It seems we can now isolate the cells and study them in a pure culture, which is something that wasn't possible before."
"We really see this as just the beginning," adds Zack. In follow-up studies using CRISPR, his lab is looking to find other genes that are important for ganglion cell survival and function. "We hope that these cells can eventually lead to new treatments for glaucoma and other forms of optic nerve disease."
To use these cells to develop new treatments for MS, Zack is working with Peter Calabresi, M.D., professor of neurology and director of the Johns Hopkins Multiple Sclerosis Center.
This work was completed through the Wilmer Eye Institute's Glaucoma Center of Excellence and its Stem Cell Ocular Regenerative Medicine Center, of which Zack is co-director.
Study co-authors were Chung-ha Davis, Vinod Ranganathan, Kellin Krick, Russ Martin, Cynthia Berlinicke, Nicholas Marsh-Armstrong and Hai-Quan Mao of Johns Hopkins; and Jeffrey Diamond and Justin Kerr of the National Institute of Neurological Disorders and Stroke.
This work was supported by grants from the Maryland Stem Cell Research Fund under grant number 2014-MSCRFI-0774; the National Institutes of Health under grant numbers T32-90040730, 1RO1EY02268001, 5T32EY007143, 5P30EY001765 and R01EY023754; and unrestricted funds from Research to Prevent Blindness Inc., the Guerreri Family Foundation, and Mr. and Mrs. Robert and Clarice Smith.
Marin Hedin | EurekAlert!
Further reports about: > Johns Hopkins > MS > culture > fluorescent protein > ganglion cells > glaucoma > nerve cells > new treatments > optic nerve > retinal
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A professional graphic designer – HTML banner maker in order to create banners for a campaign. This campaign has 8 concepts. For each concept we will brief the developer with frames scenario, instructions for animation, colors to be used. All graphics will be provided. After approval of each concept's first banner (master) it must be adapted to other
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I am creating a database for a college of about 80 classrooms and meeting spaces. This database will focus on audio and visual technologies in each classroom as an asset management tool for the college.
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Ive had a boy friend that stayed at a gospel mission in seattle and complained an complained how bad they were there. He came over to my house, which im not blaming him, he has never been bitten. Plus we had another person at our house that came over that has the same problem. Ive been getting bit for about 4 months. Kids sleep in my room an they havent got bit at all. I bombed the room, ive vacuumed, scraped mattress,washed all clothes several times in hot water searched everywhere took off matting that was on my box spring and I could not find a single one!!!! Well since i bombed I havent been bit, but tonight as i was sitting here i finally saw one crawling on my clothes that were on the floor. Now im freaked out! Could there only be one? Or do they always produce a family?
The prognosis for bedbug bites is excellent. The vast majority of people who experience bedbug bites will recover without any long-term problems, and many individuals who are bitten may not exhibit any physical signs at all. However, the recent resurgence in bedbug infestations will require increasing public education and awareness, instituting effective preventive and control measures, and continuing research into the development of more effective, safe insecticides.
The next sign is that the bites will occur nightly while sleeping and the rashes will increase daily. These rashes will usually be located on the legs, arms, neck, face and back, which are the most common areas. The reason these places are the most common sites is because these areas are usually exposed during the night. Exposed areas of the host are what they prefer.
Health.com is part of the Meredith Health Group. All rights reserved. The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments. All products and services featured are selected by our editors. Health.com may receive compensation for some links to products and services on this website. Offers may be subject to change without notice. See the Terms of Service and Privacy Policy (Your California Rights)for more information. Ad Choices | EU Data Subject Requests
The significant resurgence of bedbugs in the past decade has been attributed to pesticide resistance, more frequent travel, lack of public awareness, and inadequate pest control programs. Bedbugs are obligate blood parasites (insect family Cimicidae). They can withstand a large range of temperatures but are attracted to warmth and carbon dioxide. They typically feed just before dawn. Cutaneous reactions to bedbug bites can include macules, papules, wheals, vesicles, bullae, and nodules. Bites may be confused with other skin conditions. Bedbug bite reactions are typically self-limited and resolve within one to two weeks without treatment. Bedbug infestation may cause significant psychological distress. The diagnosis of a bedbug infestation is based on history, appearance of bites, and inspection of sleeping quarters. Although there is no evidence that bedbugs transmit disease, systemic reactions may include asthma, angioedema, generalized urticaria, iron deficiency anemia, and, rarely, anaphylaxis. An integrated pest management strategy should be employed to eliminate infestation. Tactics include vacuuming, heat or cold treatment, trapping devices, and pesticides.
Bed bugs often hide in seams, folds and crevices of mattresses, box springs, bed frames and headboards. A thorough inspection requires dismantling the bed so that upper and lower seams and surfaces can be examined. Things to look for are the bugs themselves, shed skins of the nymphs (immature bed bugs), and the blackish fecal spots. The dark spots of dried bed bug excrement are often present along mattress seams or wherever the bugs have resided. Box springs afford many places for bed bugs to hide, especially along the upper seams and underneath, where the bottom edge of the box rests on the frame. If an underlying dust cover is present, it may have to be removed to gain access for inspection and possible treatment. Successful treatment of mattresses and box springs can be difficult, however, and infested ones may need to be discarded or encased in a protective cover.
While you are sleeping, bed bugs will bite using their mouthparts, commonly referred to as beaks. As they bite, they release an anticoagulant in their saliva preventing your blood from clotting. This allows them to receive a steady two- to three-minute blood meal—what they need in order to survive and reproduce. Bed bugs will not bite in defense, they will only bite for the sole purpose of feeding.
For about 3 almost 4 weeks now something has been bitting me around my ankles and feet. My fiancé hasnt been bit by anything and if he has he can't tell. I took all sheets off the bed, found nothing. i have no idea if its bed bugs or fleas. But the itching is driving me insane. My fianc roommate did bring a stray kitten into the house not to long ago, and I'm thinking its fleas. But I don't know for a 100%. I have a couple bites on my arms but mainly on ankles and feet.there is no carpet in house, just hardwood and one rug in living rm. I saw 2 tiny tiny bugs last night, but I couldn't grab them in time. Pplease help its driving me insane and grossing me out
I am apparently allergic to these things. My bites swell to huge sizes and I get red marks running up my arms and it itches like crazy, almost like a burning itch. However, doing some research I found an effective way to stop the itch. Its not for everyone, but for someone like me who can't even touch the shells (my fingers have gotten swollen searching for the damn things), this works for me. Again, not for everyone:
Another solution you hear about is vacuuming. You can vacuum up a lot of insects, but eggs are harder to get, and vacuuming won't in and of itself kill bed bugs. Indeed, vacuuming can end up spreading bed bugs to other rooms—when emptying the canister, for example. Pest control operators who use vacuums take measures to prevent bed bugs from escaping when the vacuum is emptied.
About five weeks ago bed bugs were found out work, then two weeks ago they spread, pest control has seen continuously coming to check and yesterday they gave the place the green light. I work with a largely indigent populace, the office I work at was not sprayed, during the night at some point, I will feel painful stings, hours later I have been finding small lumps or even large and hard ones, Could it be bed bugs? There is a particularly painful lump on the back of my thigh, it's very hard too.
Bed bugs are obligatory bloodsucking. They have mouth parts that saw through the skin, and inject saliva with anticoagulants and painkillers. Sensitivity of humans varies from extreme allergic reaction to no reaction at all (about 20%). The bite usually produces a swelling with no red spot, but when many bugs feed on a small area, reddish spots may appear after the swelling subsides.[15] Bedbugs prefer exposed skin, preferably the face, neck, and arms of a sleeping person.
Found worldwide, bedbugs are most common in developing countries. Still, reports of bedbugs in luxury hotels are not uncommon. They are most commonly found in areas like hostels, hotels, shelters, and apartment complexes where there are many visitors coming and going. When they enter your home, it's often because they have hidden in luggage, furniture, clothing, or boxes that are being moved. They can also travel on pets' fur. Increases in international travel may be responsible for the rise in bedbug sightings.
Barriers: You can purchase bedbug-proof encasement covers for mattresses, box springs, and pillows. Also get bedbug interceptors to place under each leg of the bed or furniture items. These also allow you to see if there are any remaining bedbugs as they get trapped in the double rings of the interceptor disks. Ensure the bed is at least 6 inches from the wall and the bedding doesn't touch the floor.
We've randomly gotten bites here and there but it's summer so we were unsure. We had a cleaning lady come in recently and use her vaccuum so we suspect that could've brought in bed bugs! Last night was worst ever but I was outside yesterday but didn't notice these bites til I just woke up. No signs of spots left behind on mattress, maybe one dot on bedding but could be anything. What do you think?? I have about 6-8 on my middle back and they are about an inch or so apart in one line across bra line area
We vacuum the carpets and bed almost everyday, wash everything every week and even sprayed every with bed bug spray. It seems to be working a bit cause they have lessened but I'm still getting bitten quite a bit. Of course they itch and I scratch a lot. I've been using the baking soda and water remedy (it works pretty well for me) but before I used to scratch until they bled and now I'm having trouble healing old bites.
Insect and spider bites and how to deal with them Insect and spider bites can occur almost unnoticed, or they can be painful. Either way, home treatment is usually enough for most symptoms. However, some bites can spread serious disease, such as Lyme disease and malaria. Find out how to protect against bites and what to do if someone has a severe reaction to a bite. Read now
The bites usually last about 7 days, even if they are treated correctly. However, if you have sensitive skin like myself, they can last a couple weeks or in my husbands case, they last only a few days. As mentioned, if you scratch the bites its going to make things worse and besides running the risk of a bacterial infection, they will also take longer to heal so keep your nails away from them!
Bedbug bites typically are stealthy and not felt by the host. This is because they inject a numbing substance into the skin along with an anticoagulant agent to prevent blood from clotting at the feeding site. Itchy, red bites on the skin may be the first sign you've been bitten. Bites are most common on the arms and shoulders, and the bites often occur in straight rows, as pictured here.
Bedbugs live in any articles of furniture, clothing, or bedding, so they or their eggs may be present in used furniture or clothing. They spread by crawling and may contaminate multiple rooms in a home or even multiple dwellings in apartment buildings. They may also hide in boxes, suitcases, or other items that are moved from residence to residence or from a hotel to home. Bedbugs can live on clothing from home infestations and may be spread by a person unknowingly wearing infested clothing.
The likelihood of bed bugs increases if the affected individual has been traveling, or if they have acquired used beds or furnishings before symptoms started to appear. Bed bugs also are suspect if you wake up with itchy welts you did not have when you went to sleep. It's important to recognize, however, that not all bite-like reactions are due to bed bugs. Confirmation requires finding and identifying the bed bugs, shed skins, fecal spots, etc., which often requires the help of a professional. (Other possible sources of irritation that may be mistaken for bed bugs are discussed in University of Kentucky entomology fact sheet ENT-58, Invisible Itches: Insect and Non-Insect Causes).
Known to be international travelers and expert hitchhikers, bed bugs are everywhere. As you travel, you increase your chances of being bit. However, knowing how to identify the bites and what your treatment options are will help you decide your next course of action. Learn more about where to look for bed bugs and how to avoid them with these great blogs:
Bedbug bites usually do not require any treatment. If you develop itching of the skin around the site of the bite, you can use an over-the-counter antihistamine pill or cream such as diphenhydramine (Benadryl). Some individuals may also experience relief from the itching by applying a hot washcloth directly to the affected area. Try to avoid scratching the skin, as this can cause skin breakdown and a subsequent secondary bacterial skin infection.
No. Bed bugs are also pests in poultry operations, and they're known to parasitize bats. Some labs that study bed bugs rear them on guinea pigs and mice. The bugs might feed on cats and dogs. Fur is probably a barrier to them, but they could feed at any place on the body without fur. Bed bugs are not specific to humans, but they are adapted to parasitizing us.
We have already replaced are furniture, threw out our bed that we still haven't be able to afford to replace I have treated the house daily with sparaies and powders. We have torn up our carpet one three rooms of the house. Did all that before getting new furniture but yet we still can't seem to rid of these bedbugs. The infestation doesn't seem to be as bad, yet we are still getting bitten nightly by them we don't have a lot of money we are struggling the way it…help what can I do
Oh, I just killed one crawling up my arm as I'm typing right now and it was filled with MY blood!!!…I don't know what to do or where to turn…I'm a senior citizen and I am on a limited income so I can't spend alot of money on this….I am so discouraged and sleep deprived that before I started typing this I sobbed for at least an hour…I cam covered in bed bug bites and treatment is not working anymore. I live in an apartment complex for people 65 and older and someone came down the hall and knocked on my door and ask me if I was alright…I just said I was having a bad night which is an understatement!!!
Last Saturday, I slept over my boyfriend's house to be safe from that hurricane that came to NY. His house is pretty infested with them, but he bombed the room where I slept, and sprayed a whole lot of bug spray on and around his mattresses, did all his blankets and pillows, and yet I've either been bitten so much, that I can't even tell if they are "breakfast, lunch, dinner" dots, or just rashes from a bad reaction to something. And the baking soda trick, to my surprise, didn't work! Grrrrr!!!
Nightstands and dressers may need to be emptied and examined inside and out, and tipped over to inspect the woodwork underneath. Oftentimes the bugs will be hiding in cracks, corners, and recesses. Other common bed bug hiding places include: along and under the edge of wall-to-wall carpeting, especially behind beds and sofas; cracks in wood molding; ceiling-wall junctures; behind wall-mounted pictures, mirrors, outlets and switch plates; under loose wallpaper; clothing and clutter within closets; and inside clocks, phones, televisions and smoke detectors.
When traveling, inspect the bedding prior to exposing yourself or your belongings. Seal your dirty clothes in plastic bags. You may even consider encasing your luggage in a plastic bag while you are in a hotel room. Launder your clothing as soon as you get home. You can treat your suitcase by vacuuming, using a clothes steamer, or handwashing it with hot water and soap. You might also consider encasing luggage in a plastic bag between trips.
Did you or someone else in your home recently come home from a trip? Bugs can stow away in clothing and in the recesses of your luggage. A good preventative measure is to check lodging you are staying in immediately after arrival. As mentioned before, signs are evident, even during the daytime, include the blood-colored excrement they leave behind.
Should I worry about a tick bite? Ticks are parasites that feed on blood, and although their bites are harmless they can still transmit diseases, such as Lyme disease or Rocky Mountain spotted fever. Learn what ticks are and how to recognize the signs and symptoms of a bite. This MNT Knowledge Center article also explains how to prevent tick bites. Read now


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Tuesday - Thursday: 17:30 - 21:30
Friday - Saturday: 17:00 - 22:30
Sunday: 17:00 - 21:00
Saturday: 12:00 - 14:00
Very tasty food and good service. Quick turnaround which is good as they are very strict on the time allocated per table.
The food was and the staff are exceptional.
A must attendance for any foodie is this new kid on the block.
Watch this space.
We really, really enjoyed our visit to Host. It was a perfect friends' Saturday dinner. We left feeling very glad to have discovered this little restaurant with creative cuisine, tasteful menus and very friendly staff. The Chef's Menu for 2 is a great option if you are new to the place or cannot decide what to order (cause all tastes great), so you can have a bit of all together with a friend or partner. Good wine list, amazing pasta, tasty appetisers, and the Rib Eye was so good! Will definitely visit again the next time we 're in Dublin!
Really loved our experience - food was fantastic, especially the rib of beef, and the atmosphere was great.
You must get the chefs selection- don't even look at the options, just go for it! Delicious food, great wine list, friendly staff
Excellent choice between small and large plates of creative and tasty food.
Every time I go to host it gets better and better even when you think it can't improve any more.
Favorite restaurant, has it all.
Bookclub Christmas evening
We enjoyed a wonderful evening at Host. Food was SUPERB - top quality and such delicious flavors. Service was excellent and so friendly - no sense of Christmas rush! This restaurant just gets better and better.. can't wait to return.
Girls Christmas night out and we could not have loved it more!!!! Absolutely amazing in every way!! 👌
The food was amazing. Best meal we've had. The flavours were stunning. A real find.
It was my first time visiting your restaurant and it was fantastic. We cleaned out plates. We will be back asap
Wonderful food - inventive and full of taste surprises
Went there for a family dinner for four and we all thought it was excellent. We had the tasting menu which was cooked beautifully. The service was friendly and timed to perfection. Also it has to be said a very relaxed vibe in the restaurant. I shall return.
Always a great experience to eat at Host- food, wine and people are all 5 star!
Amazing food! Lovely staff. I've been twice and I'm already planning my next visit
Great atmosphere and the food was good! Don't like how you only get a 2 hour time slot. Because we arrived 15 minutes late they wouldn't let us do the tasting menu with 1h45 min left. They also didn't let us order dessert. This new 2 hour time slot system in Dublin is ruining the overall dining experience.
Food was great. The staff were brilliant, very friendly and accommodating. Background music taste was also class.
Highly recommend!
Also enjoy going to Host for a night out with my boyfriend. Tasty good food, great value and nice atmosphere always made feel welcome. Highly recommend :)
Another delicious meal at Host. I just love it here. We dined early so the restaurant was quite empty but the food was once again stellar.
Fantastic food great service. Group of 6 girls and we loved it
Second time at Host, just as great as the first time. Had the Chef's menu, which means you get 2 starters, 2 pasta dishes, 2 sides and one main course and one dessert to share for 2 people. That gives you a lot of different, well prepared, seasonal dishes to try. My favourites were the mozzarella with candied beetroot and the pasta. All great value at 35 per person, and we felt well taken care of by the staff. Menu changes daily, so we will have to come back. Great for dates - how someone deals with food sharing is the real relationship test. By the time we got dessert, I was full enough to handle dessert sharing, so all's good!
Lovely food- beautifully presented and smallish wine list but very well selected wines. Lovely service from people who really care.
Love Host! Fabulous food, fantastic atmosphere, perfect service, a total 10 out of 10! Can't wait to go back!
Food and service was great. The chef did a great job providing a vegan option. Definitely coming back
I love this restaurant, second time at Host and it was as good as the first, I think this is now at the top of my list for Dublin restaurants due to the quality and the value. My entire party were extremely happy with the food and staff. I would really recommend the lamb chops, burrata and any of the pasta dishes. I'll be back :D
Host was fabulous!! The food was of a very high standard! The rib eye was really excellent! There was a great atmosphere!
We will be back
Really enjoyed my first visit to Host. I had a catch up with my friend over a glass of wine and some pasta. The atmosphere of the place was extremely pleasant and comfortable. The food was delicious - I will definitely be back to try some dishes from the lunch menu. I feel like it can be a good place for reading a book over a cup of coffee in the afternoon or for a date in the evening.
The venue creates a really nice atmosphere as soon as you enter. The perfect size and love the way the tables are set up. The host was so welcoming and the entire team was so attentive. The food was unbelievable, personal favourite was the pasta. Will definitely be back. Thanks for a fantastic night.
Lovely casual dining in a modern convenient setting. There's always something delicious to look forward to here.
Enjoyed every minute of it. Atmosphere really pleasant .Staff really helpful and both portion size and food quality excellent. Wine selection interesting but good. Veg selection a little disappointing but nothing to quibble about. Will be back
Everything was amazing but the noise level is very high - the only downside - apart from that everything was perfect !!
Brought a friend for their first visit - they fell in love and immediately booked a dinner event. Great food and service - always get a sense of super team work from the kitchen through to front of house - friendly, buzzing and with quality food - highly recommended
Couldn't have been better in terms of food and service.
Excellent quality food in a lovely relaxed environment
Friendly, nice styling and intimate space wise. We found the music a bit loud. Kind of meant folk were shouting but maybe that's the vibe. We ordered too much with the sharing menu and an extra main for three people but it was all tasty and looked great, the started are great. I always find Dublin overpriced and this was similar but it's a good place with good food.
As a total foodie I can be pretty picky and having eaten here on many occasions I'm always happy to return. Wine List is always growing and very well thought out. They are outstanding when it comes to the pasta dishes which is always easy on the wallet and lets you splurge on the wines.
Another great meal in one of my favourite restaurants. Lovely god and service
Another really enjoyable experience at Host, great food, wine and staff!
Top tip .... if you are booking in the winter request a table away from the door as you get a full blast of cold EVERY time the door opens! Other than that it is great!
Excellent food really impressed with the tasting menu
Lovely! Would recommend and will return. Had the chefs menu which seemed to be most popular.


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Discrimination against women in Kenya has for many years been widespread and widely accepted. Every day we hear of rising cases of injustices based on gender, class, physical disability, sex and religious beliefs in Kenya. Sometimes it goes to extreme cases of sexual harassment against women in Kenya and other times unfortunately domestic violence, where women are beaten senseless by their husbands as a way of them showing their superiority, in which at times the consequences are fatal.
The Federation of Women Lawyers in Kenya was establi Continue reading ...
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Climate 2017, 5(2), 37; https://doi.org/10.3390/cli5020037
Evaluating Vegetation Growing Season Changes in Northeastern China by Using GIMMS LAI3g Data
State Key Laboratory of Remote Sensing Science, Institute of Remote Sensing and Digital Earth, Chinese Academy of Sciences, Beijing 100101, China
Environmental Monitoring Center of Hebei Province, Shijiazhuang 050037, China
Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China
State Key Laboratory of Resources and Environmental Information System, Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Maoyi Huang
Received: 29 November 2016 / Revised: 8 May 2017 / Accepted: 17 May 2017 / Published: 22 May 2017
(This article belongs to the Special Issue Dynamics of Land-Use/Cover Change under a Changing Climate)
AbstractAccurate understanding and detecting of vegetation growth change is essential for providing suitable management strategies for ecosystems. Several studies using satellite based vegetation indices have demonstrated changes of vegetation growth and phenology. Temperature is considered a major determinant of vegetation phenology. To accurately detect the response of vegetation to climate variations, this study investigated the vegetation phenology in the northeast (NE) region of China by using in-situ temperature observations and satellite-based leaf area index estimates (LAI3g) for the period 1982–2011. Firstly, a spatial distribution of the averaged phenology over the 30 years was obtained. This distribution showed that a tendency for an early start of the growing season (SoS) and late end of the growing season (EoS) was observed towards of the southeastern part of NE China, with the late SoS and early EoS occurring at higher latitudes. Secondly, the temperature-based and satellite-based phenological trends were analyzed. Then the significant advanced trend (SAT), significant delayed trend (SDT), and nonsignificant trend (NT) of SOS and EOS in NE region of China were detected by using the Mann-Kendall trend test approach. Finally, changes in phenological trends were investigated by using the temperature-based and satellite-based phenology method. A comparison of the phenological trend shows that there are some significant advanced trends of SOS and significant delayed trends of EOS in the NE region of China over 30 years. The results of this study can provide important support of the view that a lengthening of growing season duration occurred at the northern high latitudes in recent decades. View Full-Text
Keywords: vegetation growth; vegetation phenology; start of the growing season (SOS); end of the growing season (EOS); China Meteorological Data (CMD); significant advanced trend (SAT); significant delayed trend (SDT); nonsignificant trend (NT); Global Inventory Monitoring and Modeling Studies Leaf Area Index third-generation (GIMMS LAI3g)►▼ Figures
Figure 1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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MDPI and ACS Style
Ni, X.; Xie, J.; Zhou, Y.; Gao, X.; Ding, L. Evaluating Vegetation Growing Season Changes in Northeastern China by Using GIMMS LAI3g Data. Climate 2017, 5, 37.
AMA Style
Ni X, Xie J, Zhou Y, Gao X, Ding L. Evaluating Vegetation Growing Season Changes in Northeastern China by Using GIMMS LAI3g Data. Climate. 2017; 5(2):37.Chicago/Turabian Style
Ni, Xiliang; Xie, Jianfeng; Zhou, Yuke; Gao, Xizhang; Ding, Lin. 2017. "Evaluating Vegetation Growing Season Changes in Northeastern China by Using GIMMS LAI3g Data." Climate 5, no. 2: 37.
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Management of Acute Non-cirrhotic and Non-malignant Portal Vein Thrombosis: A Systematic Review
- 2.1k Downloads
- Citations
No definitive evidence exists regarding the treatment of acute portal vein thrombosis (PVT). Treatment modalities described include conservative management, anticoagulation, thrombolysis, and thrombectomy. This review examines the impact of such treatment, its outcomes, and the complications resulting from the resultant portal hypertension.
A Medline literature search was undertaken using the keywords portal vein thrombosis, anticoagulation, thrombolysis, and thrombectomy. The primary end point was portal vein recanalization. Secondary outcome measures were morbidity and the development of portal hypertension and its sequelae, including variceal bleeding. Data from articles relating to PVT in the context of cirrhosis, malignancy, or liver transplant were excluded.
Early systemic anticoagulation results in complete portal vein recanalization in 38.3% of cases and partial recanalization in 14.0% of cases. Spontaneous recanalization without treatment can only be expected in up to 16.7% of patients. Frequently this is only when associated with self-limiting underlying pathology and/or minimal thrombus extension. Thrombolysis can be associated with major complications in up to 60% of patients.
The natural history of acute PVT is poorly described. Spontaneous resolution of acute portal vein thrombosis is uncommon. Early anticoagulation results in a satisfactory rate of recanalization with minimal procedure-associated morbidity. Thrombolysis should be used with caution and only considered if the disease is progressive and signs of mesenteric ischemia are present. Further well-designed trials with precise outcome reporting are needed to improve our understanding of the disease.
KeywordsPortal Vein Portal Hypertension Thrombolytic Therapy Portal Vein Thrombosis Superior Mesenteric Vein
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- 27.Tateishi A, Mitsui H, Oki T et al (2001) Extensive mesenteric vein and portal vein thrombosis successfully treated by thrombolysis and anticoagulation. J Gastroenterol Hepatol 16:1429–1433PubMedCrossRefGoogle Scholar
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Minnesota Attorney General Debate
Clip: Season 2019 Episode 3 | 35m 54s
Candidates Keith Ellison, Noah Johnson and Doug Wardlow debated legal topics.
Aired: 09/21/18Video has closed captioning.
Clip: Season 2019 Episode 3 | 35m 54s
Candidates Keith Ellison, Noah Johnson and Doug Wardlow debated legal topics.
Aired: 09/21/18Video has closed captioning.
Second District Congressional Race
Mary Lahammer previewed the hotly-contested race between Jason Lewis and Angie Craig.
The Wrap | How Almanac Does Debates
Producer Brendan Henehan explained how Almanac organizes its political debates.
Political Panel | AG Race and Kavanaugh Hearings
Panelists Annette Meeks, Noah Rouen, Sarah Walker and Javier Morillo-Alicea.
New members of congress, budget forecast, holiday baking
Jim Hagedorn + Dean Phillips, budget forecast, remembering President George H. W. Bush
New light rail line, Steeles holiday tunes, poli sci panel
SW light rail, winter storm, holiday tunes by the Steeles, political scientist panel
Keith Ellison, a Kevin Kling story, a holiday recipe
Atty General-elect Keith Ellison, profile of Peggy Flanagan, a Kevin Kling holiday story
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Region: McLaren Vale, SA
I often go to the small restaurant 'Fino' in the southern McLaren Vale town of Willunga. Sharon, who runs the front end, has a good wine selection and when I ask for a glass of something new and interesting, it is often a local Cabernet.
The seaside influence that develops the wine flavours in McLaren Vale wines is not far away in this variety and I detect a cooling, mintiness which is most attractive and merges into the bigger warmer flavours. This makes for a complex mix and the wines do well in the show ring with McLaren Vale Cabernets being awarded a good share of the top trophies and the golds. There is also a pleasing contrast between McLaren Vale and Barossa Cabernets and I urge you to drink them side by side. The maker of the wine was Nicholas Bourke and we are pleased with his talent and believe our customers will be as well.
Region: Limestone Coast, SAPrinceland remembers part of our past as this was the proposed name for a new state between Victoria and South Australia. For Glug customers Princeland is about the fabulous value we find from the vast region that encompasses Coonawarra, Wrattonbully, Padthaway and another dozen or so districts. A must for a serious consumer is to visit Coonawarra as it does have a hallowed feeling. The beauty of the reds of Coonawarra meant numerous other areas were planted with vines. These of course do not have the same reputation as Coonawarra and we find beautiful, full bodied reds, in our view identical to Coonawarra can be purchased at low prices. For Shiraz you need to go to vineyards that are warmer thus we do not favour coastal regions. Padthaway and Bordertown, the limestone plateau east of Naracoorte, and a few other spots is where you find the Shiraz gold and at good prices.
Region: McLaren Vale, SAExperiments began over 10 years ago, back in 2009, to develop a sappy, tasty red to open after a luncheon white. A red which has flavour but low to very low extract, resembling say a Yarra Valley Pinot, yet sourced from South Australia with a different mouthfeel to a big Barossa Shiraz. Benjamin settled on McLaren Vale Grenache and this is the fourth release. As you can see from the alcohol the Perfect Press does not develop the feel of lightness from low alcohol, low extract, and low flavor from early picked or unripe fruit but by using a variety like Grenache and not fermenting on skins for long and not returning the pressings to the wine. This is nailing the flavours I had envisioned back in the early 2000s.
Region:Limestone Coast, SACoonawarra is justly famous and a pilgrimage to Penola, the local headquarters, was an essential for a young wine merchant back in the 1970s. Much has happened since then and Coonawarra is now the 'capital city' of a vast area called the Limestone Coast.Over the last decades we have found many great bargains and the Kincraig is one of these. Glug does not make wine from the Limestone Coast but we have many contacts and from a regular supply of samples find what we are after for the right price. The best reds are made from Cabernet which gets full ripeness in this cooler region. With Shiraz we are much more cautious and knock back most samples. We do not want and do not expect a Barossa Valley look alike but we do like ripeness. This is a good wine and will give customers much pleasure. It has now been in barrel for many years so you will discover oak on the palate. This is the final bottling.
Region: South Australia
Small parcels of back vintage wine exist in many wineries. Wineries are good housekeepers and these lots are well looked after. At some time though they must be sold and thankfully we get a few of the right calls. Benjamin has done a wonderful job with this base, and recall we purchased way too much of this vintage, so we had several interesting varieties to add to the final blend. Lastly and 'please forgive us' if you are the ultimate purist the final blend was freshened with younger Barossa wine. The Adelaidean concept first appeared in 2015 as we wanted a large multi-district regional name which would allow us to blend wines from premium places like the Clare Valley, McLaren Vale, Barossa Valley and Langhorne Creek. Thus Adelaidean-Mount Lofty wines come from the continuous range which extends 350 kilometres from the Southern Flinders to Kangaroo Island.
Region: Barossa Valley, SA
The Stockwell Reserve is a gorgeous wine from a single vineyard of 40 year old bush vines on Belvidere Road in the northern Barossa.
A few months back I talked to four of the best Barossa winemakers about Mataro. What I was told was summed up best by Rolf Binder, 'it's an intellectual variety'. I discovered reasons why this remarkable variety was forgotten and you can read about this on Glug.
As often mentioned the best wines are made in small volumes and we only bottled 55 dozen of this wine after it had spent 20 months maturing in puncheons. My notes show that before oak we had left the wine on skins for 18 days after fermentation, a risky but rewarding procedure which large companies would never contemplate.
Of all the Mataro's we sell this Stockwell best displays the wonderful characters of this variety; the 'Chinese spices' of Tim Smith, the 'slippery tannins' of Rolf Binder, the 'nuts and spices' of Kym Teusner and the 'delicacy and fragrance' of Pete Schell.
Each mixed Dozen contains:
Oakley Adams Langhorne Creek Shiraz 2016
Bagot Station 'Captain's Table' Barossa Valley Dry Red Blend 2016
P B Burgoyne McLaren Vale Cabernet Sauvignon 2014
Restless Farm 'The Camel' Coonawarra Cabernet Sauvignon 2015
Village Belle Barossa Valley Cinsault 2017
Kincraig Limestone Coast Cabernet Sauvignon 2015
Light and Finniss McLaren Vale Cabernet 2014
P. B. Burgoyne Langhorne Creek Shiraz 2016
Oakley Adams Coonawarra Cabernet 2015
Stonevale 'Red Barn' Barossa Valley Grenache Mataro 2016
Light and Finniss Adelaidean SA Big Dry Red 2012
Restless Farm 'The Bunny' McLaren Vale Shiraz 2016
Includes a FREE copy of Mike Langfords photographic book on Tasman Peninsula (70 pages) which we sell for $29.90. I was with Mike when he took the photos which is how I obtained the book remainders. The mix is a compelling, add in the REF savings and you have a bargain.
Each case contains:
Rara Avis Barossa Valley Mataro Grenache 2013
Stockwell Creek Reserve Barossa Valley Shiraz 2014
Grandma Raethel Barossa Valley Shiraz 2015
Karrawirra Single Vineyard Moculta Barossa Valley Cabernet 2015
Trennert Reserve McLaren Vale Shiraz 2012
Stockwell Creek Reserve Barossa Valley Shiraz Durif 2013
Then to fill the box you receive six bottles of a kitchen red, Trial Bin 657 South Australia Merlot Cabernet NV for free, value $35.00. There is also a saving on the six premiums of $31.00 plus included a FREE copy of Mike Langfords photographic book on Tasman Peninsula (70 pages) which we sell for $29.90. Langford is a multiple winner of the Australian Landscape Photographer of the Year and I was with him when he took the photos which is how I obtained the book remainders.
Contains 1 bottle each of the following wines:-
The reds of South Australia are very special. The reason is the geography of the premium vineyard regions means the climate is a balance between cooling and ripening in a way which is not found anywhere else on the globe. The bunches of grapes are pulled towards the coolness of the Great Southern Mega Ocean which slows flavour development, which can alter quickly by the intense, inland, heat flowing in from the baking, red centre. It is this balance, constantly tilting, which makes complex, intense, interesting flavours which are best referred to as warm flavoured reds. Though a grower in Coonawarra may well disagree. Any-way this is the second mix of a wonderful new selection.
Contains 1 bottle each of the following wines:-


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Sundays at 9 AM EST
Below, you will find a collection of recent sermons and sermon series:
2018-12-09 – Heartcry – Worship: A Sacrifice of Praise
2018-12-02 – Heartcry – Worship: Not Just for Church
2018-11-25 – Heartcry – Worship: A Fresh Perspective Due to copyright laws we are unable to post and archive the video that was included in this. sermon: "LEARNING TO WORSHIP IN THE DARK" by David Uth. Please visit RightNow Media to view video: www.rightnowmedia.org (Please contact the church office for a free account to view…
2018-11-18 – Heartcry – Getting Ready for the End
2018-11-11 – Heartcry – GOD WANTS our LIFE TO BE an OPEN BOOK
2018-11-04 – Heartcry – Be Strong and Courageous
2018-10-28 – Heartcry – God Wants Me to Be Happy
2018-10-21 – Heartcry – There are Many Ways to Heaven
2018-10-14 – Heartcry – God Won't Give You More Than You Can Handle
2018-10-06 – Heartcry – Suffering Always Results from Sin


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Force Ten 3
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By Zohra Bellahsène, Michel Léonard
This e-book constitutes the refereed court cases of the twentieth foreign convention on complex info platforms Engineering, CAiSE 2008, held in Montpellier, France, in June 2008. The 35 revised complete papers and nine revised brief papers provided including 1 keynote lecture have been conscientiously reviewed and chosen from 273 submissions. The papers are prepared in topical sections on duality and approach modelling, interoperability of IS and agencies, refactoring, info platforms in e-government and life-science, wisdom styles for IS engineering, standards engineering for IS, conceptual schema modelling, carrier infrastructure, provider evolution, versatile info applied sciences, metrics and approach modelling, details procedure engineering, and IS improvement with ubiquitous applied sciences.
Read Online or Download Advanced Information Systems Engineering: 20th International Conference, CAiSE 2008 Montpellier, France, June 18-20, 2008, Proceedings PDF
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