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UNC Lineberger News
N.C. Cancer Hospital on "Great Oncology Program" list
Becker's Hospital Review has named the N.C Cancer Hospital as one of "70 Hospitals with Great Oncology Programs."
Triangle Bladder Cancer Support Group: Here to Help
Bladder cancer patients in the Triangle area are not alone. They have a monthly group where "true loving support for each other" is shared, says David Langham, a bladder cancer survivor and one of the organizers of the group.
UNC and partners to study policies to restrict tobacco marketing at point of sale: multi-institutional $6.7 million research grant awarded
The way tobacco products are marketed and sold changed with the June 2009 passage of the Family Smoking Prevention and Tobacco Control Act. For example, this law mandates larger and stronger warning labels on packs and advertising and prohibits the sale of "light" and clove cigarettes. The FDA Act also now allows states and local communities to regulate the time, place, and manner of tobacco advertising. Thus, states could restrict tobacco promotions or restrict the location of tobacco advertising.
UNC scientists collaborate on colon cancer therapy comparative effectiveness study
In 2008 UNC and Harvard University's Brigham and Women's Hospital in Boston were selected by the U.S. Agency for Healthcare Research and Quality to carry out accelerated practical studies examining the comparative effectiveness of cancer treatments. The collaboration is called the Cancer Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Comparative Effectiveness Consortium.
Chase Jones pitches Basebald for the Cure to teams across the country
When Chase Jones organized Basebald for the Cure, he hit a home run!
Latest in treatment for Hodgkin Lymphoma, Park comments at annual ASH meeting
As part of Patient Power® coverage of the annual meeting of the American Society of Hematology (ASH), UNC Lineberger member Steven Park, MD, talks about the latest in treatment for Hodgkin Lymphoma.
Tar Heel 3-point shots benefit UNC Lineberger thanks to Coca-Cola
Coca-Cola and Tar Heel Athletics team up to help cancer research and treatment.
real doctors, real people - Paul Godley
Whether photographing a child in the streets of Vietnam or consulting with a patient about a diagnosis, Dr. Paul Godley employs his intuition and charming personality to put the person in front of him at ease within a matter of moments.
UNC scientists collaborate to find first major genetic mutation associated with hereditary prostate cancer risk
Chapel Hill - After a 20-year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the disease.
UNC radiation oncologists co-author Journal of Clinical Oncology editorial on breast cancer radiotherapy and coronary artery stenosis
Timothy Zagar, MD, assistant professor of radiation oncology, and Lawrence Marks, MD, professor and chair of radiation oncology, co-authored an editorial in the December 27, 2011 issue of the Journal of Clinical Oncology.
UNC surgeons co-author study on breast cancer treatment decision making
Chapel Hill, NC - How much medical information does a woman understand and retain about her breast cancer diagnosis? UNC scientists participated in a four-institution study involving 440 women with early-stage breast cancer and found that breast cancer survivors had limited knowledge about their surgical options, including an understanding of something as important as the risk of recurrence.
Technology tackles dieting and exercise, Tate comments
Deborah Tate, PhD, associate professor in the Department of Health Behavior and Health Education and the Department of Nutrition at UNC-Chapel Hill, is quoted in the article "Latest gadgets give diets, workouts a high-tech boost" published in today's issue of The News & Observer.
UNC Lineberger geriatric oncology program leaders co-author Journal of Clinical Oncology editorial about older women and breast cancer
UNC Lineberger Geriatric Oncology program leaders Hy Muss, MD, and Jan Busby-Whitehead, MD, co-authored an editorial in the December 10, 2011 issue of the Journal of Clinical Oncology. Muss is professor of medicine. Busby-Whitehead is professor of medicine, and director of the UNC School of Medicine's Center for Aging and Health and Division of Geriatric Medicine.
New research study examines behavioral economics of colorectal cancer screening in underserved populations
CHAPEL HILL, N.C. – A new study at UNC Chapel Hill will examine what complex and conjoined behavioral factors influence low income people to pursue colorectal cancer screening and what strategies could increase screening rates in disadvantaged communities.
UNC GI oncologists author editorial in the Journal of Clinical Oncology
UNC Lineberger GI Oncology program directors Joel Tepper, MD, and Bert O'Neil, MD, co-authored an editorial in the December 10, 2011 issue of the Journal of Clinical Oncology. Tepper is the Hector McLean Distinguished Professor of Cancer Research. O'Neil is associate professor of medicine.
Nancy Thomas, MD, PhD, appointed first Irene and Robert Alan Briggaman Distinguished Professor
Nancy E. Thomas, MD, PhD, was appointed the first Irene and Robert Alan Briggaman Distinguished Professor. The professorship is named in honor of Dr. Briggaman, who served as chair of the UNC Department of Dermatology from 1987-1999, and his wife, Irene.
Hepatitis C virus hijacks liver microRNA
Mechanism explains how virus survives in the liver and how a new antiviral works
Gonzalez-Crespo talks about his work as a Spanish interpreter and what it means to him
Ruben Gonzalez-Crespo, a Spanish interpreter at UNC Lineberger Comprehensive Cancer Center, was highlighted in the November 2011 issue of the University Gazette in an article titled "Former singer finds new voice helping others battle cancer."
UNC radiation oncology resident Nathan Sheets wins ASCO Merit Award
The Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO) will award 20 oncology trainees with Merit Awards at the 2012 Genitourinary Cancers Symposium. The symposium will be held February 2 - 4, 2012 in San Francisco.
Wrapped up in making a difference
Tori Frahm has experienced just eight Christmases, but she epitomizes the true spirit of the holiday. She and her family organized collection and delivery of 750 presents for pediatric oncology patients and their siblings at UNC Lineberger Comprehensive Cancer Center. The gifts helped 125 families have a brighter holiday.
Sing a song of hope - local caroling tradition brings cheer each year
One neighborhood in Cary has become the centerpiece of a holiday tradition that benefits UNC Lineberger.
Editorial urges rapid clinical trials for targeted breast cancer therapies
Chapel Hill, NC – In an editorial published today in the Journal of Clinical Oncology, UNC associate professor E. Claire Dees, MD, reviews current evidence on the safety and efficacy of combination therapies currently used for metastatic breast cancer and urges clinical researchers to move forward with new studies that leverage advances in the identification of tumor biomarkers.
UNC Lineberger remembers Marci Campbell
Dr. Marci Campbell, professor of nutrition at the University of North Carolina Gillings School of Global Public Health, died December 14 after living with cancer with grace and caring for almost two years.
Six UNC faculty recognized by prestigious international scientific society
Six University of North Carolina at Chapel Hill faculty members have been named fellows of the American Association for the Advancement of Science.
UNC scientist elected Fellow of American Institute for Medical and Biological Engineering
Weili Lin, PhD, has been elected a Fellow of the American Institute for Medical and Biological Engineering. Lin was cited for his outstanding contributions to the development and translation of MR functional neuroimaging.
American Cancer Society Revises Cancer Screening Guideline Process; UNC scientists are report co-authors
ATLANTA –December 13, 2011– The American Cancer Society has revised its guideline formation process to achieve greater transparency, consistency, and rigor in creating guidance about cancer screening. The new methods align with new principles from the Institutes of Medicine (IOM) by creating a single generalist group for writing the guidelines, commissioning systematic evidence reviews, and clearly articulating the benefits, limitations, and harms associated with cancer screening tests. The new process is outlined in a Special Communication in the December 14, 2011 issue of the Journal of the American Medical Association.
The power to help, hurt and confuse: direct-to-consumer whole genome testing
CHAPEL HILL – The era of widely available next generation personal genomic testing has arrived and with it the ability to quickly and relatively affordably learn the sequence of your entire genome. This would include what is referred to as the "exome," your complete set of protein-coding sequences.
UNC scientists funded to study genome sequencing in clinical settings
Chapel Hill - The complete sequence of an individual's genome – all 3 billion DNA building blocks - will soon be affordably available to doctors, patients and even consumers. While knowledge of one's genome may have important medical benefits, tremendous questions remain regarding an avalanche of such data means and how they should be used. Many clinical, ethical and social issues arise from the evaluation, use and sharing of the data.
Donald Rosenstein serves as president of Academy of Psychosomatic Medicine
Donald Rosenstein, MD, professor of psychiatry and medicine in the UNC School of Medicine and director of the UNC Comprehensive Cancer Support Program, will serve a one-year term as president of the Academy of Psychosomatic Medicine. Dr. Rosenstein is a member of UNC Lineberger Comprehensive Cancer Center.
President Obama taps Barbara Rimer to lead National Cancer Panel
President Obama has announced his intent to nominate Barbara K. Rimer, DrPH, Dean and Alumni Distinguished Professor of the University of North Carolina Gillings School of Global Public Health, to chair the President's Cancer Panel. The panel was established as part of the National Cancer Act, signed by President Nixon in 1971
Cell molecule identified as central player in the formation of new blood vessels
The molecule is the protein Shc (pronounced SHIK), and new blood vessel formation, or angiogenesis, is seriously impaired without it.
P Rex-1 protein key to melanoma metastasis
UNC scientists contribute cell studies and protein expression analysis
Viruses and cancer focus of Damania's talk at National Academy of Sciences annual science symposium
Blossom Damania, PhD, was a speaker at the Twenty-third Annual Kavli Frontiers of Science Symposium, held November 17-19, 2011 in Irvine, California. The symposium is hosted by the National Academy of Sciences.
Gehrig named director of UNC Gynecologic Oncology
Paola Gehrig, MD, associate professor of obstetrics and gynecology, has been named director of UNC Gynecologic Oncology. In her new role she will oversee gynecologic oncology in the School of Medicine's Department of Obstetrics and Gynecology and the UNC Lineberger Comprehensive Cancer Center.
Protein associated with childhood cancer alters the structure of DNA, leading to cancer, UNC study shows
Chapel Hill - UNC scientists have demonstrated for the first time how a critical gene associated with a type of childhood cancer alters the way DNA is packaged in cells and leads to cancer. Their laboratory discovery could result in the development of a targeted therapy to treat Ewing Sarcoma, a malignant bone and soft tissue tumor of children and young adults.
Scarring a necessary evil to prevent further damage after heart attack
CHAPEL HILL, N.C. – After a heart attack, the portions of the heart damaged by a lack of oxygen become scar tissue. Researchers have long sought ways to avoid this scarring, which can harden the walls of the heart, lessen its ability to pump blood throughout the body and eventually lead to heart failure. But new research from the University of North Carolina at Chapel Hill School of Medicine shows that interrupting this process can weaken heart function even further.
Biomedical Research Imaging Center to be fourth U.S. site for MRPET scanner
Chapel Hill, NC – UNC's Biomedical Research Imaging Center (BRIC) will be the fourth site in the United States to obtain a leading-edge imaging system called an MRPET scanner (also known as a PET-MRI). The machine will first be installed in current BRIC building but will be moved to the new building going up adjacent to the UNC Lineberger Comprehensive Cancer Center, and BRIC director Weili Lin, PhD, is already strategizing with top experts in the field to put this innovative technology to good use.
No evidence for potential competition between human papillomavirus types in men
Chapel Hill - The Centers for Disease Control and Prevention Advisory Committee on Immunization Practices recently recommended that teenage boys be vaccinated against the human papillomavirus.
University of North Carolina and SAS fight cancer together
UNC Lineberger and SAS developing technology that tracks patient characteristics, treatment and outcomes
Dianne Shaw named Hometown Hero for November 8
WCHL named Dianne Shaw a Hometown Hero for November 8, 2011. Each weekday the station selects a Hometown Hero who goes "over and above the call of duty," exemplifying excellent service and dedication to others in the community.
NBC Nightly News looks at latest research on aging, Sharpless comments
Ned Sharpless, MD, professor of medicine and genetics and associate director for translational research at UNC Lineberger, commented on Mayo Clinic's latest research on aging on the November 6, 2011 broadcast of the NBC Nightly News.
Loretta Muss named Hometown Hero for November 4
WCHL named Loretta Muss a Hometown Hero for November 4, 2011. Each weekday the station selects a Hometown Hero who goes "over and above the call of duty," exemplifying excellent service and dedication to others in the community.
Growing without cell division
CHAPEL HILL, N.C. - An international team of scientists, including biologists from the University of North Carolina at Chapel Hill, may have pinpointed for the first time the mechanism responsible for cell polyploidy, a state in which cells contain more than 2 paired sets of chromosomes.
2011 Oncology Nursing Excellence and Clinical Excellence Award winners announced
Chapel Hill - The Oncology Nursing Excellence and Clinical Services Excellence Awards recognize four employees who exemplify the very best in cancer care at UNC Lineberger Comprehensive Cancer Center and UNC Cancer Care.
Chapel Hill's big running event to benefit UNC Lineberger
Wells Fargo Tar Heel 10 miler and Fleet Feet 4+ mile run take place April 21, 2012
Study links chemotherapy response to heritable factors
Findings guide future research on chemotherapy resistance
Multidisciplinary research urged for optimal melanoma surgery
UNC surgical oncologist co-authors Lancet editorial
UNC scientists offer first evidence of using biologically targeted nanoparticles to boost radiation therapy effects
Chapel Hill - Making a tumor more sensitive to radiotherapy is a primary goal of combining chemo and radiation therapy to treat many types of cancer, but with the chemotherapy drugs come unwanted side effects.
UNC scientist receives grant to identify biomarkers for breast cancer recurrence risk
Chapel Hill - A UNC scientist was awarded one of seven grants presented by the Avon Walk for Breast Cancer at their seventh annual event in Charlotte, NC.
Study confirms males and females have at least one thing in common: upregulating X
Cellular "mathematics" help equalize X chromosome gene expression
Morning UV exposure may be less damaging to the skin
CHAPEL HILL – Research from the University of North Carolina at Chapel Hill suggests that the timing of exposure to UV rays – early in the morning or later in the afternoon – can influence the onset of skin cancer.
UNC cancer researcher awarded top V Scholar ranking
The V Foundation for Cancer Research announced this week that Greg Wang, PhD, has been awarded the Martin D. Abeloff, MD, V Scholar Award. This award goes to the research project that receives the highest rating from the V Foundation's Scientific Advisory Board. Wang was tied with Hongwu Zheng, PhD, of Cold Spring Harbor Laboratory for this honor and is the 10th V Scholar from UNC Lineberger.
UNC nanotech entrepreneur to speak at TEDMED annual conference
Joseph DeSimone, PhD, has been invited to join an elite list of speakers at this year's TEDMED Conference in San Diego, Calif., Oct. 25 – 28.
Fast Break Against Cancer raises more than $210,000 for cancer research and treatment
Coach Roy Williams' 7th annual Fast Break Against Cancer raised more than $210,000 for cancer research and treatment at UNC Lineberger and in our community.
Study quantifies false positives for yearly mammograms
Breast Cancer Surveillance Consortium also compares digital and film mammography
Event honors Durhams, raises money to name a consultation room in their honor
Woody and Jean Durham were honored on October 13 in Chapel Hill for their volunteer service to UNC Lineberger Comprehensive Cancer Center at a dinner called "A Toast to Woody."
Meet Kimryn Rathmell, MD, PhD - a kidney cancer doctor at UNC Lineberger
Kimryn Rathmell, MD, PhD, thrives on discovery, whether in her lab developing a new experiment for kidney cancer or in her kitchen trying out a new food or cuisine.
Spotlight on Terry Magnuson - his work featured on UNC's website
Terry Magnuson, PhD, Sarah Graham Kenan Professor, Chair of the Department of Genetics, and Vice Dean for Research at the School of Medicine, is featured in a spotlight story on UNC-Chapel Hill's website.
Earp talks about the creation of UNC Lineberger on "Good to Great at Carolina"
UNC-Chapel Hill Chancellor Emeritus James Moeser talks with Shelley Earp, MD, director of the UNC Lineberger Comprehensive Cancer Center, about the creation and development of the cancer center. This discussion is the third in a series based on the book "Good to Great" by Jim Collins.
Project to improve use of cancer support services
Grant from the Centers for Disease Control focuses on younger breast cancer patients
UNC scientists recommend rethinking brain MRI for early-stage lung cancer patients
UNC scientists report that in early stage, asymptomatic non-small cell lung cancer, early brain recurrences are potentially detectable prior to surgery and recommend that physicians consider including a routine pre-operative staging brain MRI. In addition, patients whose tumors are determined to be higher risk based on the findings at surgery, should consider post-operative MRI to offer early treatment of unrecognized metastasis.
UNC researcher to help lead new esophageal cancer network
Dr. Nicholas Shaheen, professor in the UNC School of Medicine, adjunct professor in the UNC Gillings School of Global Public Health and director of the UNC Center for Esophageal Diseases and Swallowing, will co-direct Barrett's Esophagus Translational Research Network (BETRNet) projects.
Jin's research highlighted in endeavors magazine
Jian Jin, PhD, an associate professor and director of medicinal chemistry in the Center for Integrative Chemical Biology and Drug Discovery at UNC-Chapel Hill, is featured in endeavors magazine.
UNC surgeon trains future surgeons in Malawi: The Malawi Surgical Initiative
Carol Shores, MD, PhD, FACS, has been interested in the link between viruses and cancer for over 20 years, after working on virus- associated cancers as a pre-doctoral fellow in the UNC Department of Biochemistry and Biophysics. Oropharyngeal cancers, like cervical cancer, are associated with human papilloma viruses and endemic Burkitt lymphoma, a childhood cancer in sub-Saharan Africa, is associated with Epstein-Barr virus.
Combination therapy beneficial for head and neck skin carcinomas, UNC study shows
CHAPEL HILL, N.C. - Patients who have high-risk non-melanoma skin carcinomas of the head and neck may benefit from concomitant radiotherapy and chemotherapy, according to a UNC-led study. Their study is the first to report on multiple patients with these skin carcinomas treated simultaneously with radio-and chemotherapy.
Laws aren't enough to make sure girls are vaccinated for HPV
Noel Brewer, a professor of public health at UNC who has also studied HPV vaccine use, said the public controversy has been less harmful than the fact that many doctors simply don't know or choose not to recommend it, or that many parents have insurance plans that don't cover the vaccine or charge large co-pays for it.
Triple-Negative Breast Cancer: Still A Hard Fight For African-American Women
Keith Amos, MD, quoted in The Huffington Post
UNC spin-off receives $3M Small Business Innovation Research grant
Chapel Hill, NC – G-Zero Therapeutics, an RTP company started in 2008 based on technologies from the University of North Carolina at Chapel Hill, has been awarded a $3 million Phase II Small Business Innovation Research Grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.
UNC Lineberger Scientist Channing Der's memorable visit with Carolina for Kibera in Kenya
Channing Der and his wife, Kathy, had already planned a 30th wedding anniversary trip to Kenya. After hearing Carolina alumnus and author Rye Barcott talk about his book, It Happened on the Way to War: A Marine's Path to Peace, and describe the Carolina for Kibera program in Nairobi, Kenya, they knew they had to see the program in action.
UNC partners with Community Health Centers to improve colorectal cancer screening
Toolkit moves best practices to the community
UNC team reports link between protein overexpression and head and neck cancer outcomes
Chapel Hill - A team of UNC scientists report that in laboratory studies, overexpression of a specific protein could be used as a prognostic marker and as a guide for therapeutic choices for patients with head and neck cancer. Their findings appear in the September 9, 2011 online issue of the journal Clinical Cancer Research.
UNC researchers identify important step in sperm reprogramming
CHAPEL HILL – When sperm meets egg, the chemical instructions that tag sperm cells must be erased so that human life can start anew. One way these instructions are erased is through demethylation, the removal of specific chemical tags or methyl groups that dot the underlying DNA of cells. Though scientists have known about this phenomenon for a decade, exactly how such "reprogramming" occurs has proved elusive.
UNC scientist proves potential of new nanoparticle design for cancer therapy
Chapel Hill - A new type of nanoparticle developed in the laboratories at the University of North Carolina has shown potential for more effective delivery of chemotherapy to treat cancer. Wenbin Lin, PhD, Kenan Distinguished Professor of Chemistry and Pharmacy, and colleagues report their finding online in advance of print on September 14, 2011 in Angewandte Chemie, the German-based flagship chemistry journal.
Weili Lin, PhD, appointed Dixie Lee Boney Soo Distinguished Professor in Neurological Medicine
CHAPEL HILL, N.C. – Weili Lin, PhD, professor of radiology, neurology and biomedical engineering and director of the UNC Biomedical Research Imaging Center, has been appointed The Dixie Lee Boney Soo Distinguished Professor in Neurological Medicine.
Large international study discovers common genetic contributions to mental illness
CHAPEL HILL – A team of over 250 researchers from more than 20 countries have discovered that common genetic variations contribute to a person's risk of schizophrenia and bipolar disorder.
Researchers identify components that keep immune system in check
CHAPEL HILL – Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body's own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.
NSF grants awarded for soft matter research
Two recent grants from the National Science Foundation will support soft matter research at the University of North Carolina at Chapel Hill.
Chemist receives NIH award to support innovative research
Kevin Weeks, a chemist at the University of North Carolina at Chapel Hill, has received an award from the National Institutes of Health to support innovative research on creating new drugs that work by binding to RNA.
ESPN anchor Stuart Scott featured speaker at Fast Break Against Cancer
Seventh annual event benefits cancer research and treatment in our community
UNC Lineberger patient Morgan Throckmorton talks with WRAL about her diagnosis, clinical trials
UNC Lineberger patient Morgan Throckmorton was diagnosed with colon cancer in 2009 when she was 24 years old. She is now part of a UNC-led trial to test a new drug, Regorafinib.
Two UNC Lineberger faculty receive 2011 Hettleman Awards
Two UNC Lineberger faculty, Noel Brewer, PhD, associate professor of health behavior and health education in the UNC Gillings School of Global Public Health, and Karen Mohlke, PhD, associate professor of genetics in the UNC School of Medicine, have received the 2011 Hettleman Prize for Artistic and Scholarly Achievement by Young Faculty at UNC-Chapel Hill.
UNC scientist to study post-mastectomy breast reconstruction surgery decision making
Chapel Hill - Deciding whether or not to have breast reconstruction after mastectomy is highly challenging for many patients. Clara Lee, MD, MPP, a UNC School of Medicine physician/scientist, has received a five-year grant award to examine patients' decision-making process about reconstruction and the effects of reconstruction on quality of life and body image. The $862,700.00 career development award to the plastic and reconstructive surgeon is from the National Institutes of Health.
Lawrence Marks, MD, appointed Dr. Sidney K. Simon Distinguished Professor of Oncology Research
Chapel Hill, NC – Lawrence B. Marks, MD, chairman of the UNC Department of Radiation Oncology, has been appointed the Dr. Sidney K. Simon Distinguished Professor of Oncology Research at UNC-Chapel Hill. The professorship, established by a $500K gift from Wally (class of '66) and Lil Loewenbaum of Austin, Texas, is named in honor of Mr. Loewenbaum's grandfather, Dr. Sidney K. Simon.
Peer Connect Program trains survivors to "guide" patients and fellow survivors
Peer Connect provides training for cancer survivors who wish to "give back" by talking with or being a buddy to another patient or survivor. Peer Connect meets a need for more formalized training for the "guides" or peer counselors by teaching effective communication skills and strategies based on Motivational Interviewing (MI), which focuses on listening and meeting the needs of the recipient rather than giving advice or telling people what to do.
Powell Hammond selected as White House Fellow
Wizdom Powell Hammond, PhD, assistant professor of health behavior and health education at UNC Gillings School of Global Public Health, has been named to the 2011-2012 class of White House Fellows, the White House recently announced.
McKenney among 17 nurses honored by local media
Susan McKenney, APRN, BC, MSN, OCN, Clinical Associate Professor of Surgery, has been selected by NBC 17, along with Chapel Hill and Durham magazines, as a Super 17 Nurse.
Grants to fund research into improving bone marrow transplant complications, outcomes
Chapel Hill, NC – Stefanie Sarantopoulos, MD, PhD, was recruited to UNC in 2009 with the help of the University Cancer Research Fund. Now she is a recipient of two grants that have helped establish her own laboratory to look into the causes of chronic Graft vs. Host Disease. Sarantopoulos is an Assistant Professor of Medicine in the Division of Hematology/Oncology and Microbiology and Immunology and a member of UNC Lineberger Comprehensive Cancer Center.
$100,000 grant from Hyundai Hope on Wheels to fund childhood sarcoma research
Hyundai Hope on Wheels and Raleigh-Durham Area Hyundai Dealers today awarded Ian Davis, MD, PhD, a $100,000 grant to support research into the causes of and treatments for pediatric sarcoma. Davis, assistant professor of pediatrics and genetics and a member of UNC Lineberger Comprehensive Cancer Center is one of 71 recipients of Hyundai Hope on Wheels' 2011 Hope Grant program, where $7.1 million will be awarded to support research and programs in honor of National Childhood Cancer Awareness Month.
Free prostate cancer screenings offered at UNC Hospitals, Sept. 21-22
Men who are 40 years old or older, or who have a family history of prostate cancer, may make an appointment in advance by calling 919-966-1316. Walk-ins are also accepted.
UNC Lineberger hosts the North Carolina Lung Cancer Partnership Advocacy Summit on August 26-27
Close to 40 participants braved Hurricane Irene to learn how to be effective advocates for lung cancer.
Cancer Conversations: a community monthly educational series for cancer patients and families
The UNC Comprehensive Cancer Support Program is sponsoring a monthly community educational series called "Cancer Conversations." Featuring UNC physicians and others, the series is a time intended to help people learn from and talk with cancer experts. The sessions will be held the third Tuesday of each month from 7:00 – 8:30 pm: September 20, October 18, November 15 (no session in December).
UNC study shows potential for nanotechnology-based therapy for ovarian cancer
Chapel Hill - A UNC-led study has shown the potential for nanotechnology therapy for ovarian cancer. Scientists at UNC Lineberger Comprehensive Cancer Center and Duke University Medical Center conducted a preclinical study using nanoparticle technology to deliver doses of chemo- and radiotherapy that specifically targeted metastasized ovarian cancer cells, eradicating the cancer and lessening the toxicities often associated with the treatment.
St. Baldrick's Foundation announces $330,000 grant to University of North Carolina at Chapel Hill
CHAPEL HILL, N.C. It takes life-saving research to Conquer Kids' Cancer! The St. Baldrick's Foundation, a volunteer-driven charity dedicated to raising money for childhood cancer research, has awarded a $330,000 St. Baldrick's Scholar award to Timothy Gershon, MD, PhD, and assistant professor of neurology at the School of Medicine at the University of North Carolina at Chapel Hill.
Causes of African-American breast cancer incidence study receives $19.3M: UNC partners to form largest US database
Chapel Hill - UNC scientist Robert Millikan will partner with Christine Ambrosone, of Roswell Park Cancer Institute, and Julie R. Palmer, of Boston University, in the most ambitious study to date of breast cancer among younger African-American women.
USA Today looks at pancreatic cancer, Goldberg quoted
Richard Goldberg, MD, physician-in-chief of the N.C. Cancer Hospital, is quoted in the Health section of USA Today's website.
V Foundation grant supports local cancer research
A grant from The V Foundation for Cancer Research is helping to fund skin cancer research at UNC Lineberger.
National Cancer Institute-funded center to study proteins for better cancer diagnosis, treatment
Proteins made by cancer cells focus of effort
Oncology nurse Delma Armstrong recognized for her patient care
Each month the Patient Resource Cancer Guide recognizes an oncology nurse who exhibits dedication and compassion for his/her patients and profession - Delma Armstrong, BSN, RN, OCN, is the featured oncology nurse for June 2011.
Working on workplace wellness, Linnan featured in an expert interview
An expert interview with Laura Linnan, ScD, CHES, is featured in News & Views, a publication of the Wellness Council of America (WELCOA).
Charles Perou, PhD, appointed May Goldman Shaw Distinguished Professorship of Molecular Oncology Research
Chapel Hill, NC – Charles M. Perou, PhD, professor of genetics, and pathology & laboratory medicine, and leader of the UNC Lineberger Comprehensive Cancer Center breast cancer research program has been appointed the May Goldman Shaw Distinguished Professor of Molecular Oncology Research. The professorship, established by a $1 million gift from Wally (class of '66) and Lil Loewenbaum of Austin, Texas is named in honor of Mrs. Lowenbaum's mother, May Goldman Shaw.
UNC scientist to partner on nanoparticle vaccine for prostate cancer
Chapel Hill - University of North Carolina at Chapel Hill researcher Joseph DeSimone, PhD, will partner with scientists at two universities and a local biotechnology company to develop a nanoparticle vaccine for prostate cancer. The Prostate Cancer Foundation awarded the UNC-Beth Israel Deaconess Medical Center/Harvard-Johns Hopkins-Liquidia Technologies consortium a Challenge Award of $1 million, one of ten such awards funded by the organization.
New UNC Cancer Care commercials now airing
New television ads for UNC Cancer Care are now airing. As we launch the UNC Cancer Care brand, we hope these ads reflect a little bit of what our outstanding clinical care programs are all about. Be sure to look for them on television! The ads can also be viewed below.
Single fatherhood due to cancer, UNC faculty offer support
Cancer is a leading cause of widowed fatherhood in the United States. Faculty with UNC Lineberger Comprehensive Cancer Center's Comprehensive Cancer Support Program authored a commentary titled "Single Fatherhood Due to Cancer" in the August issue of the journal Psycho-Oncology outlining challenges these fathers face and future directions to develop supportive interventions for them and their children.
Molecular delivery truck serves gene therapy cocktail
CHAPEL HILL, NC – In a kind of molecular gymnastics, scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with "misfolded" proteins.
Breaking down blood clots, Moll quoted
Stephan Moll, MD, is quoted in an article titled "Blood Clots Pose Threat to All of Us," published today on Fox Business' website.
Welcome the 2011 radiation oncology residents
Six new residents have begun their training with the UNC Department of Radiation Oncology.
Rapid rise of robotic surgery in treating cancer, Stitzenberg quoted
Karyn Stitzenberg, MD, MPH, is quoted in an article titled "Tracking the Rise of Robotic Surgery for Prostate Cancer" published in the August 9, 2011 issue of the NCI Cancer Bulletin.
Campbell sees cancer as a team sport
Marci Campbell, PhD, MPH, RD, authored a guest editorial titled "Cancer is a Team Sport" for the August 2011 issue of the Clinical Journal of Oncology Nursing.
Whitehurst stands up to cancer through research
Angelique Whitehurst, PhD, and her Stand Up to Cancer research grant were featured in an article in the August 2011 issue of Nature Medicine.
Lifetime Televison looks at colon cancer, talks with Dr. Richard Goldberg
Richard Goldberg, MD, physician-in-chief of the N.C. Cancer Hospital, talks with Kristy Villa, one of the hosts of Lifetime Television's "The Balancing Act" about colon cancer.
UNC-Duke ties lead to collaborative finding about cell division & metabolism
Discovery may have implications for many diseases
Lisa Carey, MD, appointed Preyer Distinguished Professor in Breast Cancer Research
Chapel Hill, NC – Lisa A. Carey, MD, Professor of Medicine, Medical Director of the UNC Breast Center and Associate Director for Clinical Research at UNC Lineberger Comprehensive Cancer Center has been appointed The Richardson and Marilyn Jacobs Preyer Distinguished Professor in Breast Cancer Research.
UNC, NC community colleges partner to prevent cancer
Project will assess needs and work to accelerate adoption of evidence-based cancer prevention interventions
"Corona Cares" program to benefit N.C. Cancer Hospital Kicks Off August 1
RALEIGH, NC – Crown Imports announced today that the highly successful "Corona Cares" charitable donation program in North Carolina will kick off on August 1 to benefit patients and families at the N.C. Cancer Hospital.
Male circumcision lowers prevalence of penile precancerous lesions among African men, UNC study finds
Chapel Hill - A University of North Carolina-led international study shows that among Kenyan men, circumcision is associated with a lower prevalence of human papillomavirus-associated precancerous lesions of the penis.
Band rocks out to raise awareness about gynecologic cancers
The article "Oncologists by day, rock stars by night" written by Rachel Saslow and published in The Washington Post on July 25, 2011 features the band, N.E.D (which stands for "No Evidence of Disease").
Jacobson receives award for his contributions to the field of fluorescence
Ken Jacobson, PhD, Kenan Professor of Cell and Developmental Biology in the UNC School of Medicine, received the Gregorio Weber Award for Excellence in Fluorescence Theory and Applications at the annual meeting of the Biophysical Society in Baltimore, Maryland.
Taking a look at telemedicine: program director talks about how it's helping to fulfill UNC Lineberger's mission
CHAPEL HILL, N.C. – The article "Telemedicine: Know why you're doing it " published online July 21, 2011 in Cardiovascular Business highlights the use of telemedicine at the N.C. Cancer Hospital.
UNC researchers identify seventh and eighth bases of DNA
CHAPEL HILL – For decades, scientists have known that DNA consists of four basic units – adenine, guanine, thymine and cytosine. Those four bases have been taught in science textbooks and have formed the basis of the growing knowledge regarding how genes code for life. Yet in recent history, scientists have expanded that list from four to six.
UNC Scientists Create "Excellent" Probe to Study Gene-Controlling Proteins
Collaboration between University of North Carolina at Chapel Hill and Canadian scientists has resulted in a molecular probe capable of specifically targeting two proteins that affect a wide range of biological functions in humans by controlling the expression of certain genes.
UNC study looks at dose levels of the breast cancer drug, tamoxifen
Using a patient's genetic information can be successfully used to manage the drug concentrations of tamoxifen, a drug used to treat and prevent breast cancer.
UNC radiation therapy faculty and student win national writing award
Chapel Hill, NC - Robert Adams, EdD, RT, CMD; Bahjat Qaqish, MD, PhD; and Jessica A. Church, BS, RT, all from UNC, and Kimberly L. MetCalf, EdD, RT, MR, from the Massachusetts General Hospital Institute of Health Professions are the winners of the 2010-2011 Jean I. Widger Distinguished Author Award from the American Society of Radiologic Technologists.
Welcome to this year's hematology/oncology fellows
Six new fellows have joined the Division of Hematology/Oncology.
New Fellowship Program in Psychosomatic Medicine Opens at UNC School of Medicine
Chapel Hill - A new fellowship training program in psychosomatic medicine is beginning at UNC, a partnership of the UNC School of Medicine Department of Psychiatry and the UNC Comprehensive Cancer Support Program, part of UNC Lineberger Comprehensive Cancer Center.
Channing Der and Yue Xiong receive 2011 Battle Distinguished Cancer Research Award
Chapel Hill - Channing Der, PhD, Kenan Professor of Pharmacology, and Yue Xiong, PhD, Kenan Professor of Biochemistry and Biophysics, have been awarded the fourth annual Hyman L. Battle Distinguished Cancer Research Award in recognition of their accomplishments in cancer research. Both are members of UNC Lineberger Comprehensive Cancer Center.
Obesity epidemic may reduce life expectancy
American life expectancies, which have climbed steadily for almost a century, may drop in years to come as the obesity epidemic progresses.
Second round of Health-e-NC pilot projects funded statewide
Technology used to promote better health and cancer prevention statewide
The Cancer Genome Atlas completes detailed ovarian cancer analysis
UNC completes miRNA and array analysis
UNC Lineberger associate director chairs national bone marrow group advisory committee
Chapel Hill - Thomas Shea, MD, will serve a two-year term as chair of the Scientific Advisory Committee for the Center for International Blood and Marrow Transplant Research (CIBMTR). He was previously elected as chair-elect. The Advisory Committee establishes policy for, and provides scientific direction to the CIBMTR.
Breland honored with Honda Inspiration Award
Recent UNC-Chapel Hill graduate and former UNC Women's Basketball player Jessica Breland – who now plays in the WNBA for the New York Liberty – was honored with the the 23rd annual Honda Inspiration Award.
UNC scientists describe new protein's role in immune response to pathogens
Chapel Hill - The human immune system is a double-edged sword. While it is finely adapted to fighting potentially deadly viruses, such as the H1N1 influenza, the mechanisms it uses to fight pathogens can have negative effects such as inflammatory disorders or autoimmune diseases.
UNC Lineberger awards inaugural clinical oncology fellow awards
Chapel Hill - UNC Lineberger Comprehensive Cancer Center honored three clinical oncology fellows with $5,000 awards for their research accomplishments and clinical excellence. These first-ever awards were given to Daniel Higginson, MD, Autumn McRee, MD, and Emma Rossi, MD.
Gary Rosson Honored by 2011 Susan G. Komen for the Cure with Co-Survivor Award
Gary Rosson was honored by the NC Triangle Komen Race for the Cure as the 2011 winner of the Co-Survivor Award. Rosson is a research associate in the lab of UNC Lineberger faculty member Scott Bultman.
Genetic finding offers hope for orphan disease
New drugs should work for rare blood disorder
Earp, Valvano discuss V Foundation support, new cancer research
Dr. Shelley Earp, UNC Lineberger Comprehensive Cancer Center director, joined Nick Valvano, CEO of The V Foundation for Cancer Research, on ABC 11's Heart of Carolina Perspectives show which aired on Sunday, June 19, 2011.
Acute Hepatitis A evades immune system more effectively than chronic cousin
Finding points new direction for study of chronic Hepatitis C
UNC project collaborating with Fayetteville community to address cancer disparities
Input sought from Fayetteville's African-American and Latino communities
UNC's Hammond helps shape national cancer agenda
Each year, the President's Cancer Panel assembles a group of experts to provide official testimony about the nation's cancer agenda. The theme changes annually – for 2009-2010 the panel focused on "America's Demographic and Cultural Transformation: Implications for Cancer." A full report was released this spring.
Goldberg, Tepper recognized by American Society of Clinical Oncology
2011 Statesman Award honors extraordinary voluntary efforts
American Society of Clinical Oncology Recognizes Hematology/Oncology Training Program
UNC Lineberger's Fellowship Program in Hematology/Oncology is being recognized by the American Society of Clinical Oncology (ASCO) this weekend at the organization's annual meeting in Chicago, Illinois.
New research looks at masculine traits and how they influence health behavior
CHAPEL HILL, N.C. - The article "Why do men die earlier?" written by Bridget Murray-Law and published in the June 2011 issue of Monitor on Psychology, looks at new research that analyzes how men take care of themselves.
Pure Gold: video captures essense of UNC Pediatric Hematology/Oncology program & its chief
Dr. Stuart Gold is division chief of UNC Lineberger's pediatric hematology and oncology program.
LIVESTRONG® Survivorship Center of Excellence Network to Host Landmark Meeting on Survivorship Care and Advocacy in Response to 2011 Report Findings
Conference will be held in Washington, D.C., Sept. 15-16. UNC Lineberger Comprehensive Cancer Center is part of a collaborative effort among leading medical institutions brought together by LIVESTRONG.
Of Mice and Men: UNC-led team solves mouse genome dilemma
Data will help scientists worldwide design better experiments.
University Cancer Research Fund updates, record poster session highlights of 2011 scientific retreat
The sixth annual UNC Lineberger scientific retreat drew a record number of posters – 68 – for the poster session and competition – and close to 150 people for the talks and reception.
Common transplant drug inhibits breast cancer growth, UNC laboratory study shows
Chapel Hill - Tacrolimus, a drug that is commonly used to prevent organ transplantation rejection, inhibits breast cancer growth in pre-clinical studies. The finding from UNC scientists was reported in the May 26th Public Library of Science.
Cancer battle changes view of donating blood
Tom May used to donate blood, but not often. If he had it to do over, he'd give as much as possible. But he can't.
Dr. Carol Otey talks about pancreatic cancer on Here's to Your Health
CHAPEL HILL, N.C. – Carol Otey, PhD talks about the hope & health that has resulted from recent pancreatic research & collaboration on the May 14, 2011 broadcast of Here's to Your Health.
UNC study examines NC cancer patient emergency department visits
Chapel Hill - When cancer patients experience medical problems, they may visit emergency departments, but how often and for what reasons, there is little data.
UNC breast cancer program recognized as national model
A University of North Carolina at Chapel Hill study has joined the ranks of an elite group of programs recognized for their contributions to reducing cancer.
Cell rigidity linked to activity in proteins associated with cancer
Innovative collaboration between physics and cell biology demonstrates pathway
Sartor Featured on Here's to Your Health
CHAPEL HILL, N.C. – Dr. Carolyn Sartor discussed the "New Life After Cancer" organization on the April 28, 2011 broadcast of Here's to Your Health. Dr. Sartor is a breast cancer survivor and former Chair of Radiation Oncology at UNC.
Goldberg Appointed to Chair 2012 Steering Committee
Richard Goldberg, MD, distinguished professor and chief of the division of hematology/oncology, has been appointed to chair the 2012 Gastrointestinal Cancers Symposium Steering Committee on behalf of the American Society for Clinical Oncology (ASCO).
UNC Lineberger Holds 35th Annual Scientific Symposium
The 35th annual UNC Lineberger scientific symposium attracted more than 530 participants. Held at the Friday Center on April 27-28, 2011, the event featured speakers on "Cell Metabolism and Cancer."
Team pinpoints role of key protein in pancreatic ductal adenocarcinoma
NCCU-UNC Lineberger scientific collaboration yields new findings
Two UNC Lineberger Physician-Scientists Selected ELAM Fellows
Prestigious Executive Leadership in Academic Medicine Program builds pipeline of women leaders
Normal stem cells made to look and act like cancer stem cells
CHAPEL HILL – Researchers at the University of North Carolina at Chapel Hill School of Medicine, after isolating normal stem cells that form the developing placenta, have given them the same properties of stem cells associated with an aggressive type of breast cancer.
UNC Scientist Receives Grant to Address Lung Cancer Disparities
Chapel Hill, NC - Samuel Cykert, MD, has received a $1.8 million five-year grant from the American Cancer Society (ACS) to study "Lung Cancer Surgery: Decisions Against Life Saving Care."
UNC-Mission Cancer Partnership Welcomes New Personnel
The UNC-Mission Hospital Cancer Partnership, part of the UNC Cancer Network, welcomes Candace Cox, RN, OCN, to the program staff.
April 2011 "Around the Town" Episode Features UNC Lineberger
Local show features UNC Lineberger
Study in roundworm chromosomes may offer new clues to tumor genome development
A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors.
UNC physician scientist receives National Academy of Sciences grant to develop cancer nanotechnology
UNC study helps clarify link between high-fat diet and type 2 diabetes
New research from the University of North Carolina at Chapel Hill School of Medicine adds clarity to the connection. The study published on-line April 10th in the journal Nature Immunology finds that saturated fatty acids but not the unsaturated type can activate immune cells to produce an inflammatory protein, called interleukin-1beta.
Tet Further Revealed! Studies Track Protein Relevant to Stem Cells, Cancer
"Tet is likely to be one of the important players for stem cell reprogramming."
UNC Physician-Scientist Receives Grant to Study Breast Cancer Brain Metastases
Prestigious Breast Cancer Research Foundation-AACR Grant funds preclinical studies
Oncology Nurses Present Grand Rounds: Beyond the Diagnosis
CHAPEL HILL, N.C. - On Friday, March 11, a group of nurses gathered for a UNC Health Care Grand Rounds presentation by Jerome Schiro, RN, MN, OCN, Pat Decator, RN, BSN, OCN, and Amy De Pue, RN, BS, OCN.
Website Serves as New Tool for Colon Cancer Patients, Goldberg Featured
CHAPEL HILL, N.C. - My Colon Cancer Coach, a new website that launched this week, serves as a tool to help people diagnosed with colon cancer.
Study Finds Shoulder Function Decreased After Breast Cancer Treatment
UNC researchers working toward a rehabilitation road map
Carey Discusses Treatment for Triple-Negative and Basal-Cell Breast Cancers
CHAPEL HILL, N.C. - The article "Next Generation Treatment for Triple-Negative and Basal-Cell Breast Cancer" written by Jonathan Batchelor and published on the website cancernetwork.com on March 9, 2011 features an interview with UNC Lineberger member Lisa Carey, MD.
UNC Study Finds Oral Tongue Cancer Increasing in Young, White Females
CHAPEL HILL, N.C. - A UNC study released this week in the Journal of Clinical Oncology finds an increasing incidence of squamous cell carcinoma of the oral tongue in young white females in the United States over the last three decades.
UNC Reaches Out to Stylists for Early Cancer Detection
C.A.R.E. Behind the Chair® program scheduled for May9
Cancer Pharmacology Expert Joins UNC Personalized-Medicine Institute
CHAPEL HILL, N.C. - Federico Innocenti, MD, PhD, has been appointed associate professor of pharmacy in the UNC Eshelman School of Pharmacy. He will serve as associate director of the UNC Institute for Pharmacogenomics and Individualized Therapy and a member of UNC Lineberger Comprehensive Cancer Center.
UNC Spinoff Wins Gates Backing for Vaccine, Nanomedicine Work
CHAPEL HILL, N.C. - A Triangle-based UNC spinoff company at the forefront of efforts to use nanotechnology to tackle diseases has received a $10 million investment from the Bill & Melinda Gates Foundation.
UNC Lineberger Physician Co-Author of Study of Screening Mammography in Women with Personal History of Breast Cancer
Promise of Genomics Research Needs a Realistic View
James P. Evans, MD, PhD is lead author of a commentary about the potential of genomic medicine.
Weili Lin, PhD Appointed Director, UNC Biomedical Research Imaging Center
Weili Lin, PhD, has been appointed Director of the UNC Biomedical Research Imaging Center (BRIC).
E-Cigarette Study Featured on Time Magazine Website
UNC Lineberger member Kurt Ribisl, PhD, was part of the study's research team.
Congratulations to UNC's Top Cancer Docs!
Sixty physicians at the University of North Carolina Hospitals are listed in the latest version of "America's Top Doctors," a compilation that is published annually by Castle Connolly Medical Ltd. Of those, 32 are members of UNC Lineberger Comprehensive Cancer Center or involved in UNC Cancer Care's multidisciplinary programs.
Goldberg Cited in USA Today
Richard Goldberg, MD is physician-in-chief of the N.C. Cancer Hospital and UNC Lineberger associate director of clinical research.
FDA Restrictions on Outdoor Cigarette Ads Near Schools May Hurt Business Less than Industry Says
When the U.S. Food and Drug Administration (FDA) proposed new rules restricting outdoor tobacco advertising near schools and playgrounds in 2009, the tobacco industry argued that such rules would lead to a near complete ban on tobacco advertising in urban areas. An article in the March 2011 issue of the American Journal of Preventive Medicine shows that the effect of these rules would be less severe on businesses than the industry contends.
Bernard, Palliative Care Team Highlighted in University Gazette
The article discusses Bernard's work with the UNC Palliative Care Program and the Supportive Care Consult Service and Clinic.
Anders, Hoadley are First Recipients of New Brain Tumor Research Award
Anders was chosen for her work on breast cancer brain metastases. Hoadley was selected for her contributions to the analysis of glioblastomas.
Gold, Henry Family Featured on WRAL
The Henry family shares the story of brothers Collin and Patrick, both diagnosed with cancer and receiving care at the N.C. Cancer Hospital.
Startup Companies Address Unsolved Problems
UNC Lineberger members are involved in over 20 active startups.
Just in Time for Valentine's Day: UNC Researchers Identify a Gene Critical for Heart Function
It's a gene called DOT1L, and if you don't have enough of the DOT1L enzyme, you could be at risk for some types of heart disease.
Sole Sisters 11th Exercise Program for Women Recruiting 2011 Participants
Interested in starting a regular exercise program and supporting a good cause?
Health E NC Projects to Improve Cancer Prevention, Outcomes
University Cancer Research Fund Enables Innovative Solutions to Complex Problems
Viral Protein Mimic Keeps Immune System Quiet
Kaposi sarcoma-associated herpesvirus produces a protein that blocks the cell's inflammatory response
Roundworm Unlocks Pancreatic Cancer Pathway
C. elegans model shows how RAS oncogene switching determines a cell's fate
Molecular Battle in Cancer Cells Offers Clues for Treatment
Researchers investigating a genetic mutation in brain cancer and leukemia patients have discovered how one cancer metabolite battles another normal metabolite to contribute cancer development. Helping the "good guys" win that battle could yield new approaches for treatment.
Oncology Winter Coat Drive Warming Hearts
Heartfelt thanks to the staff of the N.C. Cancer Hospital, fellow UNC employees, our volunteers, patients, families, and friends. The Oncology Winter Coat Drive was a tremendous success - 107 winter coats were collected and distributed to our families and their caregivers throughout the month of January until February 11, 2011. Hats, scarves, gloves, and socks were added to each winter coat selection as needed. A very special Valentine's Day thank you to all for sharing your hearts!
Your Questions, Our Experts
An Interview With Oncology Clinical Pharmacist John Valgus, PharmD, BCOP, CPP
UNC Lineberger Primary Benefactor for the Wachovia Tar Heel 10 Miler - Chapel Hill's Largest Running Event
Breast Cancer Genetic Subtyping Licensed for Development
Technology developed by UNC Lineberger members may lead to diagnostic test
UNC-led Team Tests Commonly-Used Antibodies
Resulting Database to Yield Big Gains for Genetic Scientists
UNC Team Discovers a Mechanistic Link Between Genetic Variation and Risk of Atherosclerotic Disease
Normal humans produce a novel, circular form of non-coding RNA that regulates aging
UNC Hospitals Earns National Recognition for Nursing Excellence
UNC Hospitals is one of 378 facilities in the world, and among only 6 percent of all U.S. hospitals, that have earned Magnet designation.
UNC Named LIVESTRONG® Community Impact Project Award Recipient
Organization will receive The Artist in Residence Program to help people affected by cancer
UNC Startup Receives Federal Grant to Kick-Start Cancer Research Commercialization
G-Zero Therapeutics funded under Qualifying Therapeutic Discovery Project
Drug That Inhibits Vascular Development Does Not Help Colon Cancer Survival
In a study published this month in the Journal of Clinical Oncology, the results of a clinical trial of the drug bevacizumab to treat colon cancer in combination with the standard therapy found that the drug did not significantly increase disease-free survival in patients with stage II and stage III colon cancer.
UNC Team Discovers Promising Target for New Pancreatic Cancer Treatments
Cell signaling protein may hold key to blocking long-studied genetic mutation
NCCU and UNC Lineberger Receive NCI Partnership Grant
$11.9 Million in awards to address cancer disparities
National Charity Tennis Event to Benefit UNC Lineberger Comprehensive Cancer Center
N.C. native John Isner and doubles partner Sam Querrey to host
UNC Lineberger Announces Jessica Breland Comeback Kids Fund
ABC Anchor Robin Roberts Guest of Honor at Kickoff Event
UNC Scientist Receives NIH Director's New Innovator Award
Project Focuses on Efficient, Low-Cost Genetic Analysis


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Heather Coble of Shippensburg was killed in Monday morning Chambersburg crash.
A 27-year-old Waynesboro man was charged with homicide by vehicle in Monday morning's fatal crash in the Borough of Chambersburg. Chambersburg police said Agustin Macias-Marquez, no address given, was driving a vehicle along Cleveland Avenue just before 12:30 a.m. when he hit another vehicle driven by Nicholas Fortenberry, 30, of Shippensburg at the intersection of Cleveland and McKinley Street. Franklin County Coroner Jeffrey R. Conner identified the passenger who was killed at the scene as 25-year-old Heather Coble of Shippensburg. Police said Fortenberry and a second passenger, 24-year-old Madison Perry of Shippensburg suffered serious injuries and were flown from the scene to York Hospital. The force of the crash left both vehicles resting against a nearby residence, police said. After Marquez was treated for unspecified injuries at Chambersburg Hospital, he was arraigned before Magisterial District Judge Glenn Manns. He also faces charges of homicide by vehicle while driving under the influence, two counts of aggravated assault while DUI, and related traffic offenses. He remains in Franklin County Jail in lieu of $350,000 bail. A preliminary hearing has been set for Jan. 8.

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Amanda Jaskot and Michael Hank, both of Butler, were united in marriage Sept. 10 at The Brick House. The Judge Lewis Stoughton officiated. A reception followed at the The Brick House.
The bride is the daughter of John and Pamela Jaskot of Butler. Parents of the bridegroom are Varity and Dave Hirtz of Butler.
The honor attendant was Kristen Elliott of Pittsburgh.
Performing the duties of best man was Joe Panei of Butler.
The bride is a 2006 graduate of Butler High School and a 2009 graduate of St. Margaret's School of Nursing.
She is a registered nurse at Seaton Hospital in Fort Hood, Texas.
The bridegroom graduated from Butler High School in 2003.
He is a Staff Sgt. in the U.S. Army based in Fort Hood.
The couple is making their home in Fort Hood.


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Float no.2901094
Temperature and salinity profiles
Time series plots
Download the data Using the float data with ocean analysis maps
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This page accesses data from several sites, so loading may take some time.
This APEX float was launched by U.K. scientists at 4°N, 66.2°E on 1 February 2008. It has recorded a total of 188 profiles, and made its last report on 25 March 2013 from 8.6°N, 51.3°E.
Interpreting the data from this and other Argo floats means thinking about the float trajectory, the climate of the region the float has passed through, and the currents that have moved the float from place to place.
Our hints on interpreting the plots give examples of the sort of thing you should look out for in the float data. You may also find useful information by looking at floats from our float selection. Choose a float from a similar location to this one, and see how the two floats compare.
Temperature and salinity profiles
Profiles of temperature (left) and salinity (right) from Argo float 2901094. The profiles show how temperature (T) and salinity (S) change with depth from the surface to 2000m. Early profiles are dark blue, the latest profiles are deep red or brown. Click on the images for larger plots. Source of plots: IFREMER/Coriolis.
Time series of temperature and salinity
Time series of temperature (left) and salinity (right) from Argo float 2901094. The sections show all the temperature (T) and salinity (S) profiles measured by the float during its life-time side by side. Each profile is represented by a very thin column where deep red is the highest values and deep blue the lowest. The colour bars on the right relate the colours to actual data values. Profile numbers are given along the top of the plot, with corresponding measurement dates along the bottom. Click on the images for larger plots. Source of plots: IFREMER/Coriolis.
Using the float trajectories with ocean analysis maps
Look at the float trajectory in Google Earth to see where the float has been. (If in doubt about how to reveal the float tracks, see our Google Earth screenshot for help.) Compare this to the maps of temperature and salinity for different depths available for example from Mercator ocean analyses.
Downloading the float data
The Argo Information Centre has more information about this float. You can also download the data from one of the Data Centres - just select Data > Data Downloads.
There are many different formats available. ASCII data can be viewed in spreadsheets such as Excel. The other data types may require more specialist software.


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Atrial Septal Defect
What is Atrial Septal Defect?
The atria are the the upper chambers of the heart. An atrial septal defect (ASD) is a hole in the wall between the left and right chambers of the atria. It is present at birth. Blood passes from the left atrium to the right atrium in babies born with ASD. This eventually can cause problems in the lungs.
Heart Chambers and Valves
Copyright © Nucleus Medical Media, Inc.
Causes, Risk Factors & Symptoms
ASD is occurs during fetal development. It is present at birth. Some cases may be caused by a genetic defect or abnormality inherited from a parent. Others can be caused by illnesses suffered by the mother during pregnancy. Most of the time, the cause is unknown.
Risk Factors
Factors that increase the risk of having a child with an atrial septal defect include:
- Smoking by the mother during pregnancy
- Down syndrome
Symptoms of atrial septal defect include:
- Tiring easily during activity
- Sweating
- Rapid breathing, difficulty breathing, or shortness of breath
- Ongoing respiratory infections
- Poor growth
- Irregular, rapid beating of the heart
- Poor appetite
People with minor to moderate defects may show no symptoms. They may not begin to show symptoms until later in life.
Diagnosis & Treatment
You will be asked about your symptoms and medical history. A physical exam will be done. A murmur may be heard when listening to the chest with a stethoscope.
Your doctor may need pictures of your heart. This can be done with:
- Echocardiogram
- Electrocardiogram
- Doppler image
- Cardiac catheterization
- Chest X-ray
- MRI of the heart – mostly done in adults
Your doctor may need to check the health of your arteries. This can be done with coronary angiography .
Small defects that produce few or no symptoms may not require treatment. Many defects may close on their own without treatment. Talk with the doctor about the best treatment plan. Treatment options include:
Surgery may be needed if large defects cause significant symptoms.
A procedure may also be performed that closes the opening without surgery. Performed in St. Elizabeth's cardiac catheterization lab, doctors insert a heart catheter in the inner part of the thigh. A closure device is inserted through this catheter.
If your condition is repaired through surgery, you may need to take an antibiotic before you have dental procedures.
The condition is a congenital defect with unknown causes. There are no preventive measures. Early diagnosis and treatment can help prevent complications.


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Artifact created by the presence of frequencies in the image that are too high compared to the sampling frequency of the sensor. Staircasing-effects or Moiré patterns are two different forms of aliasing.
Ratio of effective focal length and entrance pupil diameter of a lens. Same as f-Number or f# or f/d. The smaller the aperture, the "faster" (brighter) the lens.
APS-C sensor
Image sensor approximately the size of an APS (Advanced Photo System) negative (roughly 25.1x16.7 mm.)
Conspicuous elements in the image that do not exist in the real scene. They may be caused by any part of the image acquisition system (optics, sensors or processing).
Backlighting, backlit
Illumination of a subject from the back. Usually the subject is dark on a bright background.
The most used pattern of photosites for color cameras, named after its creator, a researcher at Kodak in 1976. Photosites are grouped by four, with two sensitive to green wavelengths, one to blue wavelenghts, and one to red wavelengths.
Change of a standard behavior. Usually Exposure Bias or White Balance Bias.
Set of phenomena following which a point-wise light source is not imaged on the sensor on a single pixel. It is due primarily to optical causes and sensor integration. If the light source moves during the integration time, the phenomenon is known as motion blur.
Estimation of the specific parameters of a device; for example, the main calibration parameters of a sensor are sensitivity, spectral responsitivity, and noise; the main parameters of a lens are distortion, vignetting, chromatic aberration and MTF.
Charge-Coupled Device: one family of electronic image sensors that output an analog signal. In a digital camera, this analog signal is converted to digital by a separate component.
Complementary metal–oxide–semiconductor: one family of electronic image sensors that output a digital signal
Collimated light source
Light source or beam whose rays are parallel. A point-wise light source positioned at a lens focal distance provides a collimated beam. A very far point-wise light source, such as a star other than the sun, can also be considered as a collimated beam.
Color filter array
A two-dimensional array of colored filters placed on top of a sensor that allow the color of the input light to be recorded. Each photosite outputs a value that depicts the light in a subset of the visible spectrum. The most-used color filter array is the Bayer array.
Color depth
The number of colors that can be coded as digital values. A color channel coded on 8 bits can represent 256 different values.
Acutance (Edge Acutance/Texture Acutance)
An objective measure of sharpness which takes into account the sensitivity of the human visual system to specific spatial frequencies and the viewing distance of an image. Edge acutance refers to the ability of a photographic system to show a sharp edge between contiguous areas of low and high illuminance. Texture acutance refers to the ability of a photographic system to show details without noticeable degradations.
Color neutrality
Characteristic of a reflection or transmission material that does not change the spectrum (though the color) of the illuminant.
Color rendering
Process that transforms the color values of the captured scene into digital RGB values displayed on an output device (screen, printer). By extension, also designates the process that transforms raw sensor values into displayed RGB values.
Contrast Sensitivity Function (CSF)
CSF is a functional description of the human visual system threshold sensitivity to the contrast (i.e. peak-to-peak luminance difference) of sine wave patterns of a range of spatial frequencies. The Contrast Sensitivity Function (CSF) is dependent on the viewing conditions, i.e. viewing distance, size of the displayed image and luminance viewing conditions.
Color sensitivity
Numerical values defined by DxO Labs researchers that represent the numbers of colors that a sensor can distinguish, up to noise. Read more
Color shading
Non-uniformity of color rendering in the field: an object may not have the same color all across the image field (see Vignetting).
Color space
Coordinate system representing the visible colors, under a given illuminant. The L* coordinate represents the luminance, while a* and b* represent color (respectively the green-magenta axis and the blue-yellow axis). The Lab color space was designed to be perceptually uniform, meaning that a same distance between two colors should be perceived as the same difference whatever those colors are.
Color temperature
Numerical value characterizing the radiation spectrum of a perfect black body. High color temperature leads to a bluish light, low color temperature leads to a reddish light.
Statistical numerical value describing the degree of dependence of two random variables.
Dark noise
Noise measured on a sensor in the absence of light. A perfect sensor should have a uniform signal in the dark, meaning no noise. See Noise, thermal [electronic]
Decibels (dB)
Logarithmic scale used to describe phenomena taking a large range of values. Decibels are not a unit and always describe the ratio to a reference value like Signal to Noise Ratio.
Numerical algorithm used to reconstruct a multi-channel image from single-value pixels that can be read on a sensor behind a color filter array (typically a Bayer sensor).
Denoising filter
Algorithm that attenuates noise in a signal to improve its quality.
Density filters
Optical elements that absorb light used to simulate different levels of illumination. They are usually chosen to be as neutral as possible (i.e. their absorption is independent of wavelength) so that they do not change colors but only intensity.
Digital signal
Signal composed of numerical value or digit (or bits). Digital signals are now widespread since they can be easily stored, copied and transmitted with no signal loss on any media.
Digital single-lens reflex
Algorithm used to reduce the dimension of an image. According to information theory, down-sampling needs to be performed so that it cancels frequencies too high (over Nyquist frequency) to avoid aliasing.
Dots per inch, describing the precision of a display device (screen, printer, fax).
Digital Single Lens Reflex: digital camera with a removable unique lens used as a viewfinder and for image capture.
DxO Noise chart
DxO Labs transmission chart with density filters used to measure noise. This type of chart has a high dynamic, and no graininess that could be measured as camera noise. Read more
Dynamic range
A numerical value describing the ratio between the highest and lowest luminance values that can be accurately measured on a sensor. Read more
DxOMark Score
The DxOMark Score reports average lens-camera performances over the whole focal length and aperture ranges.
The DxOMark Score is reported using a gauge that shows the score itself as well as the range of scores over the focal range. WIth this gauge, photographers can view the homogeneity of the lenses image quality over their focal range.
The DxOMark Score is measured for defined exposure conditions corresponding to low-light scene with 150 lux illumination and an exposure time of 1/60s. These conditions were chosen as we believe low-light performances are very important for today's photography and it is also important for photographers to know how well lenses perform at the widest aperture.
Read more about the DxOMark Score for lenses and how it is designed.
Distortion is the variation of the magnification of the lens throughout the image field. In practical terms, photographic distortion describes the degree to which a lens cannot render straight lines in a scene as straight lines in the final image. Read more about how distortion is defined, measured and scored.


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Linked by Thom Holwerda on Mon 2nd Feb 2009 18:00 UTC
A long time ago, we asked everyone to show their desktops, and we figured it would be nice, on this (for me) cold and dreary Monday to do that all over again, over two years later. The questions remain the same: cluttered or clean? Icons or no icons? Dual or single panel layout in GNOME? How free-form is your Plasma desktop? Are there any real computer users in here (as in, using CDE)? Read on for my own two desktops.
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Arch Linux and KDE 4.2 featuring Bespin theme. Been after that maccish feeling...


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Things people do in the name of fun.
People do any number of things in the name of "fun." Some of the activities folks undertake to amuse themselves you wouldn't catch me doing on a bet, dare or under threat.
A little Web research turned up a list of "hobbies" that many insurance companies turn their noses up at. The list includes:
1. Extreme mountain or rock climbing.
2. Skydiving and B.A.S.E. jumping, where people jump from buildings, antennas, bridges or rock formations.
3. Scuba diving.
4. Private aviation, which not only includes going up in a plane, but hot air ballooning and hang gliding.
5. Racing a car, motorcycle, go-cart or any other form of motorized vehicle.
6. Back-country skiing.
7. Extreme water sports such as power boating or boat racing. White water rafting and surfing are typically included.
8. Boxing.
9. Bungee jumping.
While not included on the list of insurance "no-nos," I found myself listening wide-eyed recently as a person told me about his experience in a Tough Mudder event that took place last month in Topeka, Kan.
For the uninformed, Tough Mudder is not a race. On the Tough Mudder Website it defines its events as a personal challenge, where the objective is "simply to complete the course."
The 10- to 12-mile course is filled with an assortment of hardcore obstacles that include mud, fire, ice-water and 10,000 volts of electricity. There are 12-foot walls to scale and underground mud tunnels through which one must slither.
Those who successfully complete the course usually need around three hours. But not everyone who pays good money to participate actually finish the course. In fact, according to organizers only 78 percent of the mudders successfully complete the challenge.
So why do it? These events, which reportedly have attracted over 1 million participants worldwide and raised more than $5 million for the Wounded Warrior Project, are intended to prepare each mudder to take on the obstacles in their life. There also is an "enormous sense of accomplishment that you feel when you overcome them." And because it is not a competition, participants are actually encouraged to forge camaraderie by helping others on the course.
I failed to ask the Tough Mudder participant I know if he completed the course. He did assure me, however, that he is already looking forward to taking part in another one.
At this point it would be appropriate for me to tell you how inspired I am, and how I'm looking forward to taking on the Tough Mudder challenge. Truth be told, I don't think I'm cut out to be a Tough Mudder.
I enjoy the fact that one of my biggest challenges is finding the TV remote amidst the pillows on the couch. Camaraderie? That's what I build with my wife, Nancy, as together we look for the TV remote.
I can't begin to imagine the hours of prep work it would take to get my body in shape to participate in (survive) such an event. I would have to say my philosophy in life is summed up by an e-mail forward sent to me recently by my brother, Larry.
"If walking is good for your health, the postman would be immortal.
"A whale swims all day, only eats fish, drinks water, but is still fat.
"A rabbit runs and hops and only lives 15 years, while a tortoise doesn't run and does mostly nothing, yet lives for 150 years."
Now before you write me off as someone whose life is totally devoid of risk and daring, just remember the next time that lightning flashes at night I'm likely out trying to photograph it. But please, don't tell my insurance agent.


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Even as utility crews from across the country swarmed New Jersey ahead of Hurricane Sandy, another industry began amassing a presence here — disaster-recovery contractors.
A big storm like Sandy is a big opportunity for companies whose work is to get hard-hit areas back in working order. But before they can begin the challenge of cleanup, they first must win business in emergency conditions that don't necessarily include standard bidding processes.
"We come in with the technical expertise and the understanding of how to do it," said Jared Moskowitz, executive vice president and general counsel at Florida-based AshBritt Inc.
The company has extensive experience cleaning up after hurricanes, blizzards, windstorms and other natural disasters, including in the Northeast. Moskowitz said his firm has the know-how to collect, dispose of and recycle everything from tree trunks to refrigerators. Just as importantly, he said, they know how to deal with the Federal Emergency Management Agency, which has an intricate set of requirements that must be met before the agency will reimburse cleanup costs.
AshBritt isn't the only firm setting up shop here. Troy Garrett, president of Minnesota-based Ceres Environmental Services Inc., said his company had personnel in place even before Sandy hit New Jersey's shores.
"I had a team out in Trenton and Philadelphia and up in New York actually riding the hurricane out, so we could assess damage and do aerial reconnaissance right off the bat," Garrett said.
Ceres is already at work in New York, but it hasn't been as easy to get work in New Jersey. That's because New Jersey chose AshBritt for a potentially lucrative, no-bid state contract. The contract serves as a ready-made framework that local governments can use if they choose to hire AshBritt; otherwise, towns and counties must either do the work themselves or go through the time-consuming process of soliciting bids.
Rather than bid out the AshBritt contract, New Jersey adopted wholesale a 300-page pre-emptive contract AshBritt signed with Connecticut in 2008, to become effective in the event of a disaster. Connecticut estimated the value of its contract with AshBritt at $100 million. The New Jersey deal simply includes a provision saying New Jersey laws win out if any contract clauses conflict with state regulations.
Bill Quinn, a spokesman for the state Department of Treasury, said the state has the authority during times of emergency to sign contracts without the normal procurement procedures.
"If they had gone through the standard bidding process, it would have taken weeks or months — and (the state had) an immediate need for capabilities which AshBritt had," he said.
Though the New Jersey contract wasn't bid out, Quinn noted the Connecticut contract was, and the New Jersey deal grandfathers in the same prices offered in the four-year-old Connecticut agreement. Moskowitz said the Connecticut bidding process took several months and involved all of his firm's national competitors, totaling more than 10 firms.
Still, the arrangement puts companies like Ceres at a competitive disadvantage.
Matthew Weng, staff attorney with the New Jersey League of Municipalities, said New Jersey sets up state contracts for a variety of services — even office supplies. He said state contracts are generally the simpler option.
"It's easier if you go through the state contract because it doesn't have to go through a public bidding process," Weng said.
Garrett said he hopes local governments will shop around, because prices can vary widely.
"They're going to overpay for the services," he said.
He believes he can save counties and towns money, in part due to lower administrative costs.
Regardless of what contractor a local government chooses, the odds are good that New Jersey workers will be involved, as both Ceres and AshBritt use local subcontractors.
"Right now, 75 percent of all the work getting done (by AshBritt) is being done by New Jersey contractors," Moskowitz said. He said that number is likely to surpass 80 percent as the company signs more towns and subcontractors.
AshBritt has engaged the Conti Group, in Edison, to locate local contractors. The firm also is taking recommendations from towns that have a reliable contractor, to see if that contractor can be folded into the state contract.
The state has also executed contracts with two debris-removal monitoring firms, a service required for FEMA reimbursement. Both companies plan to hire New Jersey workers.
"Once we determine where our services are needed, we typically hire new local staff to meet those needs, as we've done with recovery efforts for more than 25 different nationally declared disaster events," said John Buri, director of client services in the disaster recovery division of Virginia-based SAIC, in an e-mail.
The other monitoring contract went to Arcadis, a Dutch firm with U.S. headquarters in Colorado.
Spokeswoman Debra Havins said Arcadis has already hired some 120 temporary staffers through its Rostan Solutions unit to help with the cleanup effort in New Jersey and New York. The company did not have a breakdown of how many new staffers were from New Jersey.
Havins said the size of its work force is likely to ebb and flow, but "we expect to keep at least 100 temporary workers for the next several weeks."
Both companies also have permanent offices in the state.
On Nov. 13, New Jersey issued a Request for Information related to debris cleanup. Department of Environmental Protection spokesman Larry Hajna said the request was related to future procurement of debris-removal management services. He said respondents were asked to provide pricing information from any previous contracts with public entities. Quinn said 28 firms responded to the request, though the names of those firms are not public.
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