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Soft tissue sarcomas arise in nearly 10,000 persons in the United States each year, and about 40% of patients die of either loco-regional disease or distant metastasis. As sarcomas and other solid tumors outgrow their blood supply, hypoxia (or oxygen deprivation) stabilizes hypoxia inducible factors 1a and 2a (HIFs), which bind to ARNT (a.k.a. HIF-?) and drive the expression of over 150 genes. These genes regulate) a variety of tumor phenotypes including tumor angiogenesis (or new blood vessel formation), invasion, and metastasis. Vascular endothelial growth factor (VEGF) is one of the genes controlled by HIFs and is also one of the most important factors driving tumor angiogenesis. HIFs and VEGF are overexpressed in human sarcomas, and increasing levels of these factors correlate with extent of disease and metastasis. HIFs and VEGF may also contribute to tumor resistance to radiation therapy. Numerous preclinical studies have found that anti-VEGF therapies can augment the effects of radiation therapy, and this synergistic effect was confirmed in a phase II clinical trial of neoadjuvant bevacizumab (an anti-VEGF antibody) and radiation therapy for sarcomas. The long-term objective of this proposal is to expand the use of agents targeting VEGF and HIFs in patients with sarcoma to reduce loco-regional recurrence and distant metastasis. Consequently, this proposal is designed to test the hypothesis that HIFs and VEGF play critical and interdependent roles in regulating sarcoma progression, metastasis, and radiation sensitivity. To test this hypothesis, this research proposal will (1) determine the role of HIFs in sarcomagenesis and metastasis, (2) determine the effects of VEGF inhibition on HIF activity, tumor invasion, and metastasis, and (3) determine the effects of HIF and VEGF inhibition on response of sarcomas to radiation. The methods of this proposal include analysis of sarcoma cell lines and primary endothelial cells in vitro, analysis of genetically engineered mouse models, and analysis of tumor tissue samples from sarcoma patients.
Oxygen is essential for tumor growth, and tumors must correct oxygen deprivation in order to expand and metastasize. In sarcomas, hypoxia (or low oxygen) stabilizes hypoxia inducible factors 1a and 2a (HIFs) which in turn upregulate (1) vascular endothelial growth factor (VEGF) which induces the formation of new tumor blood vessels and (2) other HIF-target genes which mediate tumor invasion and metastasis. This project will examine the critical and interdependent roles of HIFs and VEGF in sarcoma formation, progression, metastasis, and radiation sensitivity, and identify therapeutic means of targeting these pathways in patients with sarcoma.
|Xie, Hong; Simon, M Celeste (2017) Oxygen availability and metabolic reprogramming in cancer. J Biol Chem 292:16825-16832
|Yoon, Changhwan; Chang, Kevin K; Lee, Jun Ho et al. (2016) Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1? inhibition, and hypoxia-activated chemotherapy. Oncotarget 7:42844-42858
|Lewis, Daniel M; Park, Kyung Min; Tang, Vitor et al. (2016) Intratumoral oxygen gradients mediate sarcoma cell invasion. Proc Natl Acad Sci U S A 113:9292-7
|Simon, M Celeste (2016) The Hypoxia Response Pathways - Hats Off! N Engl J Med 375:1687-1689
|Hayano, Koichi; Tian, Fang; Kambadakone, Avinash R et al. (2015) Texture Analysis of Non-Contrast-Enhanced Computed Tomography for Assessing Angiogenesis and Survival of Soft Tissue Sarcoma. J Comput Assist Tomogr 39:607-12
|Yoon, C; Lee, H-J; Park, D J et al. (2015) Hypoxia-activated chemotherapeutic TH-302 enhances the effects of VEGF-A inhibition and radiation on sarcomas. Br J Cancer 113:46-56
|Tan, Marcus C B; Yoon, Sam S (2015) Surgical management of retroperitoneal and pelvic sarcomas. J Surg Oncol 111:553-61
|Kambadakone, Avinash; Yoon, Sam S; Kim, Tae-Min et al. (2015) CT perfusion as an imaging biomarker in monitoring response to neoadjuvant bevacizumab and radiation in soft-tissue sarcomas: comparison with tumor morphology, circulating and tumor biomarkers, and gene expression. AJR Am J Roentgenol 204:W11-8
|Lee, Hae-June; Yoon, Changhwan; Park, Do Joong et al. (2015) Inhibition of vascular endothelial growth factor A and hypoxia-inducible factor 1? maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculature. Int J Radiat Oncol Biol Phys 91:621-30
|Yoon, Changhwan; Park, Do Joong; Schmidt, Benjamin et al. (2014) CD44 expression denotes a subpopulation of gastric cancer cells in which Hedgehog signaling promotes chemotherapy resistance. Clin Cancer Res 20:3974-88
Showing the most recent 10 out of 16 publications


text: Is it possible to ever lose weight when you are hypo without being over medicated? I have a lot of weight around my tummy and look pregnant. Since starting NDT it has reduced slightly but before hypo symptoms I was a size 8-10 and I hate it my tummy was very flat. Does exercise reduce it ever as before I knew I was hypo and not on any meds I would walk, run 6 miles a day and actually ended up putting on weight.

subset: commoncrawl


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Larken Rose published an excellent article ("You Should Be Offended") recently where he discusses his experiences with confronting people with the truth. This article really resonated with me because I deal with very similar situations almost on a daily basis, and I share much of Larken's views on this. Here are some quotes from his article that I liked in particular:
It may seem a tad ironic that, as someone who advocates a society based upon voluntary peaceful coexistence, I think it's a good thing that some people are capable of being confrontational, argumentative bastards who don't mind insulting and offending others. […] I'm talking about people willing to tell the truth even when the truth is not popular, and even when telling the truth can earn one the scorn and hatred of the general public.
It is neither brave nor useful to go around loudly telling a truth that everyone already knows. What matters—what changes the world—is people telling the truth when the rest of the world doesn't know it, and doesn't want to hear it. Going around today and proclaiming, "Slavery is wrong!" doesn't require any courage or fortitude. The time to proclaim that was back when much of the world still thought that slavery was proper and legitimate, even righteous. What needs saying today is whatever truths still make people uncomfortable.
Even in a free society, there will still be ways in which people are rewarded for speaking about "safe" topics that the majority will approve of, and punished for undermining people's paradigms and going beyond their comfort zones. But if you want to see the nauseating results of what happens when someone tailors and waters down his message in the hopes of pleasing everyone—or as many people as possible—you need look no further than politics: a huge substance-free parade of empty suit puppets spewing whatever vague, meaningless, feel-good tripe might dupe the moronic majority into supporting them.
In the long run, there is an advantage to having such an outlook. Yeah, you may be broke, and possibly despised by everyone you know, but at least people will know that you are genuine, that you say what you think, and that your soul is not for sale.
I absolutely hate watering down or sugar-coating anything I have to say. When done "correctly" it's essentially a form of mind-manipulation — something I despise and avoid as much as I can. And when it's not done "correctly" it's an ineffective way of communication, because it distorts your message and your message can lose much of its impact or meaning by the time it reaches your audience. This can cause a lot of misunderstandings. Not to mention that it's a complete waste of any mental energy that you have to put into worrying and transforming your message so that it might be perceived in a more positive way by people. In my experience it's a much better approach for the long term to keep your message clear, frank, direct and to the point. Lean and mean; no beating around the bush.
People often complain that I'm too direct, too sharp or come across too offensive in my communications. The earliest I can remember getting such feedback was when I was around 20 years old, and wrote an internal email to the management team at one of my first full-time employers. In that email I expressed my criticism with the way things were going in the company, while, of course, also offering my views on ways to improve things. The feedback I got later from one of the managers was that I was "very sharp" and that he "almost felt attacked" and that I might want to consider "choosing my wording more carefully" in the future. But choosing my wording more carefully has never been, and will never be, my style. So other subsequent employers had to deal with my frankness and directness as well.
And the reason why I choose to be like this, is because I know from experience that it's the best approach. People might get uncomfortable, maybe even offended, but your message will have been received in absolute clarity, free from any noise and bloat, and will be precisely understood (eventually). And I like to communicate in this way especially if it concerns telling the truth to people and pointing out that they're wrong, in the hope that they might change and improve themselves. Especially in such cases, sugar-coating or watering down your message will seldom motivate people to change in the right way. Even if you bring it to them as polite and respectful as possible, the truth will often hurt people, it might shock them when they first learn about it, and it might even completely shake up and destroy their worldview. But all of that is needed in order to leave a mark in their subconscious (or unconscious) that will eventually motivate them to change. Consciously they might (try to) shut themselves off from your message, but subconsciously it will continue to keep them busy — you can be absolutely confident of that. What has been seen/heard, cannot be unseen/unheard. You'll eventually come to notice the effects. And sometimes change is a relatively slow process, so be realistic about your expectations and don't expect results too soon.
I admit that even for me, the truth can be painful to accept sometimes, especially when I find out that I've been wrong, but I also know that it's an opportunity for me to grow. The truth can only hurt or offend you if you've been living a lie. And I don't want to live a lie. I want to be true to myself, and to everyone else.
If you think that dealing with (people like) me might be difficult, think about how painful it eventually always is to deal with people who have hidden agendas, who're not being truthful, and who're being hypocrites in your presence. How will you feel about them when you find out later what they really think? Wouldn't you rather deal with people who are honest, genuine, and tell you exactly what they think? 😉
Wat is nou de "waarheid"? Iedereen heeft zijn of eigen versie van de "waarheid". Een subjectieve waarheid zou ik dat noemen. In dit artikel praat jij over de waarheid gebaseerd op feiten en objectieve waarnemingen. De waarheid doet zeker pijn. En een individu kan zich zelf pas "open minded" noemen als hij of zij deze waarheid kan testen of neerleggen naast dat wat hij of zij altijd heeft gedacht/geleerd wat de waarheid is. Zelfreflectie is ook de sleutel. Een waarheid moet gebaseerd zijn op feiten niet op meningen. De laatste alinea heeft de spijker op de kop geslagen. Dat doet zeer zeker zeer. In zo een geval waardeer ik het als een individu de waarheid spreekt en open is t.o. mij. Maar dan nog moet er naar mijn mening een zekere balans zijn. Ga geen "waarheid aan een persoon verkopen om deze bewust te pesten. Woorden/zinnen met een negatieve lading uitgesproken door een persoon voor jou kan als een kogel door het hart aanvoelen en jouw hele leven achtervolgen.Verkondig een objectieve waarheid of een waarheid dat op feiten is gebaseerd aan een persoon of personen, zodat het hun kan helpen om hun ogen te openen, hun zelf en hun omgeving te helpen verbeteren of een proces te laten triggeren die kan leiden tot een betere samenleving. Hoe mensen deze waarheid gaan opvatten is weer een ander verhaal. Want de waarheid doet pijn. Woorden kunnen heel krachtig werken op een mens en dan heb ik het over de negatieve effecten. Spreek zoveel als mogelijk de objectieve waarheid ook al doet het pijn maar op lang termijn is het voor beide partijen goed. Al dan niet in de relatie of zakelijke sfeer.


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Hey Doggies!
I'm so excited to tell you Canyon and I had our very first doggy playdate today. We met up with A LOT of doggies at Dogtown outside of Philadelphia. They have a very nice indoor play area with artificial turf and they even have a fire hydrant to pee on! I got to meet lots of blogging huskies today. Sasha and Isis and Magnum and Blue (and their newfie sister, Ananya) and about 9 other doggies, including MaPaw foster brothers Rocky and Buck (who are still looking for their furever home).
Canyon and I hope you enjoy our little slide show of our playdate.
Canyon was a little shy at first, but Pa (from MaPaw) was there and helped him to come out of his shell, although he always made sure he knew where mom and dad were in case he got scared. Kelsey wasn't too upset since she got to stay home and catch up with her old friend, Hennessy. If you remember, about 2 weeks ago Hennessy came for a trial visit and this morning he came to stay for about 10 days while his mom and "new" dad go on their honeymoon to Europe. We are doing our best to make Hennessy feel at home. We even tried to teach him some husky play out in the yard this afternoon. We will tell you more about Hennessy tomorrow.
Kisses, Sky boy


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|Romantics Courses
|Adriana Craciun (U. Nottingham)
|Nineteenth-Century British Women's Poetry
|Prose of the Romantic Period: Women Writers
|Women in Literature, 1790-1996
|Paul Brians (Washington State U.), Reason, Romanticism, & Revolution (includes study guides)
|Ron S. Broglio & Bill Ruegg (U. Florida), Writing About Visionary Selves and Virtual Landscapes (course on Romantic and post-Romantic writers, including Blake, W. Wordsworth, Coleridge, M. Shelley, Kerouac, Delillo, Ginsberg; taught in a "networked writing environment" utilizing online pedagogical tools and assignments)
|Canon Dreaming (I) (links to "online course syllabi in the Romanticism field that either revise the canon or explore the history and theory of canon-making"; part of the
|Stuart Curran (U. Penn)
|English Romanticism: The First Generation
|Romantic Poets
|Neil Fraistat and Susan Sniader Lanser (U. Maryland), Romanticism and Revolution, 1789-1807
|Michael Gamer (U. Penn)
|The Enlightened Sublime: Poetry and the French Revolution
|Gothicism and Romanticism
|Romantic Poetry
|Romantic Production: Communities of Reaction, Revolution, and Reform ("materials and contexts of the first generation of Romantic Writing, focusing particularly on notions of literary production and how they relate to theories of community. We will pay particularly close attention to the rhetorical traditions
|Sex, Violence, Law, and Gothic
|Gary Harrison (U. New Mexico), Studies in British Romanticism (graduate course)
|Steven Jones (Loyola U., Chicago)
|Industrial Romanticism (course on late 18th- and early 19th-century literature and the Industrial Revolution)
|Studies in the Romantic Period
|Laura Mandell (Miami U., Ohio)
|The Early Romantic Period: 1789-1816
|Rethinking Literary History: The Eighteenth- and Early Nineteenth-Century British Novel (course)
|Jerome J. McGann & Patricia Meyer Spacks (U. Virginia), The Novel of Sensibility
|Jerome J. Mcgann (U. Virginia)
|Incarnate Textualities: Blake, Dickinson. D. G. Rossetti
|David S. Miall (U. Alberta)
|Gothic Fiction (course)
|Romantic Poetry and Prose (course)
|The Shelleys (course)
|Wordsworth and The Prelude (course; includes abstracts of critical literature on the poem and Romanticism)
|Ashton Nichols (Dickinson C., Penn.), Wordsworth and Hardy (course that reads across the Romantic/Victorian divide; makes extensive use of technological tools to link classes at Dickinson C., Gettysburg C. and Franklin & Marshall C.)
|Janice Patten (San Jose State U.), Romanticism
|Romanticism Courses (Michael Gamer, U. Penn)
|Morri Safran (U. Texas, Austin), Masterworks of Literature: British (includes use of Morri Safran and Daniel Anderson's
|Will Scilacci (U. California, Santa Barbara), Rise of the Reader High and Popular Readers in the Romantic Period (hypothetical course designed as part of graduate seminar on "Canon Revision")
|William B. Warner (U. California, Santa Barbara), Cyborg Genealogies: The Gothic (studies "a selective group of novels and films and theoretical texts so as to trace the modern cyborg back to the gothic monster") (Transcriptions Project, U. California, Santa Barbara)
|Daniel E. White (U. Penn), Writing about British Romantic Poetry


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MINNEAPOLIS, Sept. 11 (UPI) -- Minnesota defensive tackles Kevin and Pat Williams can play before a decision on whether they used a banned substance, a federal appellate court ruled Friday.
Last season, both players received four-game suspensions for using a product containing a possible masking agent for steroids.
The players are arguing the positive test results should be excused because the NFL knew about the presence of bumetanide, an unlisted ingredient in StarCaps, an over-the-counter supplement, and did not advise the league's players.
Neither has tested positive for steroids, and Friday's ruling by a three-judge panel of the 8th U.S. Circuit Court of Appeals in St. Louis upheld previous rulings by U.S. District Judge Paul Magnuson in Minneapolis this this summer.
The players' case against the NFL continues in Hennepin County (Minn.) District Court.


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The higher the thermometer climbs outside, the higher the risk of gestational diabetes, according to Canadian researchers.
In the database study, and after adjusting for influential risk factors, each 10°C increase in mean 30-day outdoor air temperature was associated with a 6%-9% relative increase in the risk of gestational diabetes mellitus, according to Gillian Booth, MD, of St. Michael's Hospital in Toronto, and colleagues.
Gestational diabetes occurred among 4.6% of women who were exposed to extremely cold mean outdoor air temperatures (≤ -10°C) in the 30-day period before screening. That percentage increased to 7.7% among those exposed to overly hot mean 30-day temperatures (≥ 24°C). Each 10°C increase in mean 30-day temperature was associated with a corresponding 1.06 (95% CI 1.04-1.07) times higher likelihood of gestational diabetes, after adjusting for factors including maternal age, parity, neighborhood income quintile, world region, and year, they wrote in the CMAJ.
"We observed a direct relation between outdoor temperature and the risk of gestational diabetes among nearly 400,000 women residing in a single urban area in Canada," Booth stated in a press release.
Booth's group used databases at the Institute for Clinical Evaluative Sciences and included women in the greater Toronto area who gave birth from Apr. 1, 2002 to March 31, 2014. Those with "extreme" preterm (<28-week gestation) or post-term (>42-week gestation) births were excluded from the study population, as were those who had type 1 or type 2 diabetes before they became pregnant.
Ultimately, 555,911 births were tracked and analyzed among 396,828 women in the area. The primary time-frame for measurement was the pregnant women's exposure to outdoor air temperatures, as compiled based on data from Environment and Climate Change Canada, the Canadian government agency overseeing environmental and related initiatives, during the 30-day period before a woman's 27th week of pregnancy, which is the time when gestational diabetes most typically occurs.
Among all pregnancies, the authors determined that gestational diabetes occurred in 35,879 (6.5%) cases for women having one birth and 6.3% among those having two or more births during the course of the 12-year study period. Prevalence of gestational diabetes among women exposed to a mean outdoor air temperature of -10°C or lower was 4.6% (95% CI 3.5%-5.3%), whereas prevalence of gestational diabetes among those exposed to a mean 30-day outdoor air temperature of 24°C or higher was 7.7% (95% CI 7.2%-8.2%). That translated to an absolute difference of 3.1% (95% CI 2.2%-4.0%).
What's more, each 10°C increase in mean 30-day outdoor air temperature was associated with an additional 1.06 (95% CI 1.05-1.07) times higher risk of gestational diabetes. Among women with two consecutive pregnancies (n=133,500), Booth's group also uncovered a 1.06 times higher adjusted odds of having gestational diabetes for every 10°C increase in temperature between pregnancies (adjusted OR 1.06, 95% CI 1.05-1.08).
Booth's group stated that the findings were consistent with previous results from other studies.
"A growing body of research supports the biological plausibility of our findings," they wrote. "Studies using positron emission tomography and involving small numbers of participants have shown the presence of stores of functional brown adipose tissue in humans that can be stimulated by even brief exposure to cold temperatures, with an exposure to cold as short as 2 hours augmenting insulin sensitivity."
Additionally, with leading climate scientists pointing to climate change as the key factor behind the record-breaking worldwide heat of recent years, Booth's group suggested that the trend lines unveiled in the study could only gain importance in the years and decades to come.
"If the association between air temperature and risk of gestational diabetes mellitus is real, then modifying the thermal environment (e.g., lowering the setting on a home thermostat or spending more time outdoors in cooler weather) may reduce risk of gestational diabetes mellitus," they wrote. "Moreover, it raises some broader questions. Climate change models forecast that the earth's surface temperature will rise by 1-2°C by the year 2050, with the greatest increase in colder climate regions. If these assumptions are correct, and our current findings are valid, then we would expect an increase in the number of cases of gestational diabetes mellitus worldwide."
The study had some limitations, including a lack of pre-pregnancy BMI for only 6.6% of births, and no information on weight gain during pregnancy, activity level, or diet. Also, the authors did not measure the direct effects of cold exposure on brown adipose tissue and insulin sensitivity.
The study was funded by the St. Michael's Hospital Foundation and the Canadian Institutes of Health Research (CIHR).
Gillian disclosed support from the Heart and Stroke Foundation of Ontario. A co-author disclosed support from CIHR Reproductive and Child Health Services and Policy Research Chair.
Gillian and co-authors disclosed no relevant relationships with industry.
- Reviewed by F. Perry Wilson, MD, MSCE Assistant Professor, Section of Nephrology, Yale School of Medicine and Dorothy Caputo, MA, BSN, RN, Nurse Planner


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Supermarkets are over-promoting fatty and sugary products using special offers and price reductions, according to a study.
Professor Paul Dobson, from the University of East Anglia (UEA), led a three-year study of consumer behaviour towards food and the impact on overeating and food waste.
He concluded that unhealthy foods receive too much promotion from supermarkets, and said the food industry must do more to promote healthy living.
"It is simply irresponsible for supermarkets to overly promote foods with high sugar and fat content," he said.
"The food industry must play a much greater role in promoting healthy diets.
"Food producers can do more by reducing the fat, sugar and salt content of processed foods, while food retailers can ensure that healthy and nutritious choices are available and affordable to all consumers and that they practice responsible marketing."
Prof Dobson said that if retailers and producers did not take responsibility, regulation might be needed.
Special offers are worth more than £50bn in sales to supermarkets and account for over a third of all consumer spending.
The research team analysed weekly price and nutrition data of a full range of food and drinks products sold over a year by four UK supermarkets - Tesco, Asda, Sainsbury's and Ocado.
They found a bias towards sugary products for price promotions, while straight price discounts were on average more skewed towards unhealthy products.
Special offers also tended to be slanted towards more unhealthy products, especially those with high sugar content.
However, multi-buys were on average more biased towards healthier items.
"While price promotions can offer savings for consumers they may not be so good for our waistlines and health," he added.
"With almost a quarter of the population classed as obese, overeating and food waste are serious concerns for modern society."
Prof Dobson is outlining his findings at a lecture in London.


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Capitals' Backstrom expects to play opening nightNHL.com @NHLdotcom
After skating with his teammates Friday, Washington Capitals center Nicklas Backstrom told reporters in Washington he did not have a concussion and expects to be in the team's lineup when the 2012-13 NHL season begins.
Backstrom reportedly was injured Dec. 26 while playing in Russia during the work stoppage and had not skated since then. He met with Dr. Jeffrey Kutcher, head of the University of Michigan's Neurosport program, earlier in the week, and Backstrom reported the diagnosis to be a sore neck.
"It was more the neck, the stiffness and all those kind of things," he said. "It was nothing serious. It feels good to be back here and practice on the ice again."
Backstrom added that after going through the informal workout with his teammates, he has no reason to doubt he'll be in the lineup for opening night.
"I feel good," Backstrom said. "I'm 100 percent. I know it's a lot of speculation about what's going on and stuff, but it's something I wanted to check out. So I went to Michigan and I got it checked out. No concussion, so we can all be calm."


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Huawei Ascend P7 Mini goes official before "regular" Ascend P7
by Apr 27, 2014 7:36 pm0
While we are waiting for the Huawei Ascend P7 smartphone to coming in the market, the Huawei is quietly release the new device that make a surprise for some people. Since the company is release the Huawei Ascend P7 Mini version.
Huawei seems trying to different strategy to offers the mini version flagship smartphone before the regular "larger size" hit the market. And now we can find the Ascend P7 Mini before Ascend P7 smartphone.
The Ascend P7 Mini is packs with 4.5 inch screen size with 940 x 540 pixels resolution and qHD display. This phone is powered by Qualcomm Snapdragon 400 quad-core processor that running at 1.2Ghz clock-speed, support by Adreno 305 GPU.
The new Huawei Ascend P7 is support by 1GB of RAM and 8GB of internal storage, while the storage can be expand using microSD card slot. The phone is also coupled with 8 megapixel rear main camera with auto-focus and 5 megapixel front facing camera.
Interestingly, this phone is packs with NFC features, USB OTG, microUSB, DLNA, A-GPS, Bluetooth and WiFi. The WiFi can be used as WLAN router so the other device can connected through the Ascend P7 Mini smartphone.
Unfortunately, there is no information about the price. But this phone has bee announced in Germany and expected to available in European market in the near future.


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Is it really unlimited?
Yes, our service allows you to have unlimited access to the Internet. However, the connection speed will be reduced until 12am once the data traffic volume exceeds 110MB(220MB on the first day)/350MB(the high speed data amount is different depending on the package) that day. After 12am, the counter is reset.
What can I do with 110MB a day?
You can do all of these within 110MB data. (Estimate)
- Surf the web:100 web pages
- Message app (LINE, Whatsapp, etc): 100 messages
- Email: 20 messages
- Facebook: View 100 updates on the news feed
110MB is not sufficient to watch Youtube(normal quality). You will finish high speed data if you watch a video for more than 20min.
Check how to save data on GetAroundJapan: How to Save Data on Smartphone While Traveling
How fast is the speed?
Theoretical maximum speed is 260Mbps(best effort). The actual speeds will vary depending on the time and location and are not guaranteed.
None of the packages suit the period I need.
Please pick one from the packages that are available. If none of the packages suit the period you need, you can either extend the rental later or simply get a longer package and return it a little early. For example, if you need it for 8 days, you can buy 7 days package now and extend 1 day later, or buy 10 days package. Tips: Depending on the period you need, it could be cheaper to get a longer package. For example, if you need it for 9 days, it is cheaper to get the 10 days package than the 7 days+2 days extension. Please compare the prices and pick the best option for you. Check the extension rate on the following page: Extend Rental Period
I am going to visit different prefectures in Japan. Will I have the internet everywhere I go?
Our SIM card uses Docomo network, which is the best in terms of coverage among all mobile phone networks in Japan. However, it is up to your device whether it can make full use of it or not. If your device supports all of the following bands, you will have stable internet pretty much everywhere you go: 3G/LTE Band 1 (2100MHz), 3G/LTE Band 19 (800MHz), and LTE Band 21 (1500MHz).
Can I use messaging apps such as Whatsapp, LINE, and facebook messenger?
Yes. Your account will work even if you change the SIM card.(When you insert a new SIM card and start an app, you might be asked to "Change Number", but just ignore the message and proceed.) IMPORTANT: If you don't have an account yet, please create one before coming to Japan. Our SIM is data SIM, therefore you cannot create a new account with apps that require a phone number for verification.
Will tethering/hot spot work?
Yes and no. Our SIM card itself does not restrict tethering, however, with some devices it does not work even if the device itself supports tethering/hotspot feature. We don't have information on what works and doesn't, so if you are planning to use the feature, please be aware that there's a chance it may not work.
For more FAQ and answers to them please check the following page: FAQ.
What is a SIM card? A SIM card is a small chip inserted in a smartphone that allows the device to get access to a mobile network. You can still use your phone overseas without swapping the SIM card, however, international roaming charges will be applied, which are not cheap. By changing the SIM card to the local mobile operator's, you can keep your device online economically.
What you need to use a CDJapan SIM card An unlocked smartphone that is compatible with 3G/LTE Band 1(2100MHz) and 19 (800MHz).
Unlocked devices mean they are not locked by a specific operator. If you buy devices directly from a particular operator, they are locked by the operator. Also, the devices that indicate a specific operator's name are most likely locked.
To use our SIM card with your phone, you will need to configure the APN(Access Point Name) setting. It does not work automatically. If you have an android device, you will create a new APN by entering the information we provide manually. If you have an iPhone or apple devices, you will download the profile using Safari browser and install the APN profile.
If you're going to use iPhone, please delete our APN profile once you have finished using our SIM card. If you don't delete it, your own SIM card outside Japan may not work properly.
For the details on how to set the APN, please check the following page: SIM Card APN Setting
If you are not sure if your phone is unlocked, or if you are not familiar with changing a SIM card, we recommend you rent a mobile wi-fi instead of a SIM card. Using a mobile wi-fi is very easy and it will work with any wi-fi enabled devices. (See our mobile wi-fi plans: Mobile Wi-Fi Rental)
You can extend your rental period easily from your My Page, anytime until the return date.
Extension packages will be available for purchase on your My Page once the package is sent out.
Check the rate on the following page: Extend Rental Period
If your device was not compatible with our SIM card, post it back within 2 days from the start date with the refund request slip enclosed in the package (the postmark date will be considered proof). When the SIM card is posted back within 2 days, the charge will be the minimum amount as below and the balance will be paid back to your credit card.
Handling fee: 300 yen/SIM
Shipping: 540 yen/order
*Express shipping fee is non-refundable.
Before ordering, please read the following page carefully: SIM Card Compatibility.
To use our SIM card, your phone must be unlocked. As long as your device can connect to 3G/LTE Band 1 (2100MHz), you will have internet access in most parts of Japan except in mountain area. In addition to 3G/LTE Band 1, the coverage will be wider and the speed will be stable if your device supports 3G/LTE Band 19 (800MHz) and LTE Band 21 (1500MHz).
We issue a full refund when an order is cancelled 5 days or more prior to the start date. There are some charges for the cancellation made later than that. The balance will be paid back to you.
For more details about Refund and Cancellation, please read the following page: Refund and Cancellation
* Once the payment is completed, a confirmation email of your order payment will be sent.
* Once your package is sent out, a delivery information email with the tracking number of the package will be sent.
* A reminder email will be sent few days before the return date.
Please read the following page carefully for the details. How to Receive the Rental Items
Post Offices at the Airports: Location and Opening hours
|Narita Airport Terminal 1
|8:30 - 20:00
|4F: Departure Lobby
|Narita Airport Terminal 2
|8:30 - 20:00
|3F: Departure Lobby
|Narita Airport Terminal 3
|Please use the post office in Terminal 2.
|Kansai(KIX) Airport
|9:00 - 17:00
|Terminal 1, 2F South
|Chubu(Centrair) Airport
|9:00 - 17:00
|Weekdays Only
|New Chitose (Hokkaido) Airport
|9:00 - 17:00
|2F: Arrival Lobby
|Haneda Airport(Domestic)
|9:00 - 17:00
|Weekdays Only
|Terminal 1, 1F (Domestic)
*Please make sure you allow yourself plenty of time to collect the package. We recommend you choose this option only if your flight is scheduled to arrive early enough before the closing time of the post office, in case the flight delays.
*This service is currently available only at the airports listed above.
*Please make sure you enter your PASSPORT NAME as the recipient of the package. You will need to present your passport to collect the package at the airport post office. When the name is different, they will not release the package.
Our service is rental. All items including SIM cards need to be posted back on the last day of your rental.
Late charges will be applied if you do not post the return envelope on the return date. We will check the postmark on the envelope as well as the data usage history.
You may be able to find the red mailbox on streets and in the airports.
*At the airports, there are no mailboxes after you pass the security check. Please make sure you post it before you proceed to the security check.
*In some terminals in the airports, there may be no mailbox. Please check the official website of the airport terminal you are going to use.
Please read the following page carefully for the details. How to Return the Rental Items


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Some strange discussions is the only way I can describe it have emerged on various media platforms with reference to two previously popular episodes as well in St James and Kingston, the latter unfolded at a party after the individual doing the blaming arrived with tests results with as we say 'blood in his eyes' it also shows that maybe the post test counselling in that matter was not effective enough or may not have been done if any. There is a deficiency in the support group meeting department as they are not continuous and are sometimes haphazard and in response a soon to be concluded pilot called 'Brothers' Positive on Positive' tried to address and better unpack with a small group of persons. It sought to fill in some of the gaps that the only hour long sessions elsewhere do not address some of the situations adequately.
Revenge via HIV blaming ought to be a thing of the past given the strides in terms of the high knowledge of safer sex and indeed post positive treatment adherence and diet alongside the support systems now available in the national program. They still need to get the medication collection part straightened out as long waits at dispensaries outside of the social workers collecting for really ill patients or disabled persons is ridiculous. An announcement via Jamaica Information Service, JIS recently though suggests that more pharmacies will be added to the mix to offer ARVs, CART and HAART prescription filling at a discounted price, the clip never mentioned the other supportive drugs for opportunistic infections such as Co-Trimoxazole to control basic infections and skin maintenance or vitamins and so on. Probably the emphasis has been too much on condom use and or prevention and not equally on sustained quality of life. Condom pinching came up as well in an online discourse which was a bit surprising to me as we thought we had gotten over that problem but apparently not.
As persons await the judgement of the pending case many have condemned the accused men; be it the partner and his roommate who he forced to assist him in dumping the body under pain of violence as well which came out in the trial and his unsworn statement. Mistakes can happen, condoms can break, less vigilance in the heat of the moment, using oil based materials as lube or when persons realise flaw but continue through to the climax while hoping for the best can be some of the avenues for facilitating transmission; outside of assaults and non consent. Overseas cases of deliberate infections have been addressed by some countries passing legislation to deal with it but this is after the fact. A recent case with an African American man just showed the madness that can flow from such matters.
An infamous incident on the outskirts of Emancipation Park in New Kingston some years ago where a man and his supposed partner ended up in an awful clash that led to security interventions and subsequently the police in 2013; yet more evidence how sensitive matters can spill out into the streets with unneeded attention or results. Accepting the positive test results as not a death sentence and that suspected infidelity or cheating needs to be and can be dealt with more effectively via conflict resolution measures and third party possible professional interventions. Fighting or violence is not the way out, if lovers really love each other even said cheating and sometimes surprise HIV positive results they should find a way out, if not they were not lovers to begin with, in the true sense but merely in a 'spirit tek' farce or tolerated relationship for matters of convenience and or co-dependency.
Then with talk of transgender persons now factoring supposedly more in HIV infection rates when really they always did as far as I am concerned, given transwomen (male to female) often have integrated themselves in the men who have sex with men umbrella group as invisibility of the trans population in HIV prevention prior was almost normative. The previous results there in HIV infection rate surveys are not brought into serious doubt if not disrepute as if the lumping was so pronounced as we are now beginning to find out then a whole new rethink will have to go into the design of the HIV response to marginalised groups. The violence that may attend to that may also have to be researched properly in the ever tendentious quest for 'evidenced based advocacy' but if the data and collection is already flawed how does the relevant agencies solve those concerns and arrive at the true situation or as close to it?
The conflation of drag queens with gay men only when feminization forced or unforced leads to the feminine aesthetic has been an issue leading to advocates, NGOs and even funders themselves misreading the landscape. More needs to be done in conflict resolution as stated above. Legislation may have to be considered for some of this but the gay/bi male populations may get left out seeing we are already marginalised by way of an archaic 485 year old piece of theocracy in a buggery law. If we do not have legitimacy in everyday life then why focus of issues affecting us via formal governmental structures.
Then there is the matter of assault driven willful infections in the MSM/transgender mismatch as the latter is seen as gay without any reassignment surgery to boot; so many stories often unconfirmed of said abuse and assault with HIV positive alleged perpetrators and yet the reporting to police is virtually nonexistent as the gross indecency or buggery charges may attend if one tries to. This is why the amendment of buggery in as far as rape is concerned between men as rape already in law covers women as a case I often referred to in former dancehall artist Zebra who has been serving a thirty year sentence after he raped and sodomised a young lady so the jury gave him 20 years for the rape and the full 10 years for buggery.
More anon
Peace & tolerance
also see:


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Bill was born in Los Angeles on August 15, 1925, the only child of William W. Taylor, Sr. and Alice Aten Taylor, formerly of Scranton, Pennsylvania. Bill Sr. was the head of the English Department at Harvard Military School, an exclusive school for boys. Alice was a typical housewife of the era. During Bill's formative years the family lived at 12928 Bloomfield St., North Hollywood, California in a typical California bungalow style house in a typical neighborhood in the San Fernando Valley.
Bill Taylor, Jr. left home on Monday, October 4, 1943 for Fort MacArthur. The following day he wrote letter 1 of this collection and we pick up the story from there.
My father, Pfc. William W. Taylor Jr. served in the 100th. Infantry Division, 399th. Regiment, Co. A. His Division saw duty in France and Germany spending 185 consecutive days on the battle line. He wrote nearly 300 letters home chronicling his service to our country. Like so many combat veterans of the war, he spoke little of his experiences, but these letters tell the story.


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The winter of 2009-10 was the worst winter in more than 30 years for much of northwest Missouri. So, it was logical to expect a milder winter this year. That was the certainly the case until the second week of January. We've almost received our annual average snowfall in just the past three weeks and up to a foot of snow is on the way.
What does that mean on the farm? Expect cattle feeding to take twice as long. If we get a blizzard (there are blizzard warnings posted) it could take triple the time. I remember a couple of times when the sun was setting and we were still feeding. Normally we would finish by 11am to noon this time of year.
I'll probably be scooping feed bunks tomorrow. If one man scoops all of the bunks, he'll end up scooping a path almost a half mile long. Tomorrow should be interesting to say the least!


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My second table for the Warmachine & Hordes World Team Championship 2013 (a rather ponderous name, especially since abbreviating it to WTC gives people all kinds of references, but usually not a game of Warmachine) was to be a Cryx table. After reading the Fluff in Colossals, I was absolutely blown away by the idea of a gigantic cave, bursting with creepy cryxian crawleys, running (or levitating) up and down among a lot of machinery where new machines are built.
I decided to twist the idea a bit from the fiction though. Where the fluff calls for a gigantic factory where Cryx's most devious contraptions are born/constructed/brougth back from death, I decided to focus more on the necrotite manufacturing part of it. Mainly for 3 reasons:
- First, because a warjackfactory is ridiculously expensive and time-consuming to make. You need lots and lots of partially assembled jacks in there and that can get quite costly quite fast. Also, painting racks of unfinished jack parts takes quite a bit more time than painting a pool filled with ooze.
- Second, because of the Gooo. It gives me an excuse to make puddles of neon-green ooze, with bits of bodies or skeletons sticking out of it. Honestly, what's not to love about that. Instant Cryx-atmosphere.
- Third, because I had already been experimenting with Hirst Arts' plaster moulds for a chemical plant. Time is tight on these tables, so being able to recycle some of the work I had already done (and probably wouldn't use for the intended project anyway) was a big advantage.
Contrary to the Khador table, I didn't want to plan too much for this one. I did a few sketches before starting, but mainly to give me an idea of atmosphere. I wanted to let the material lead me this time. A cave should look organic, so I like to create it in an organic way. I already had a few buildings and pipe clusters, so I decided to just start without a plan and see what the chaos would bring me.
I did make a drawing for the ground floor though. Like I said before, it is quite easy to make the side boards look interesting, it is a lot harder to make the table itself look interesting. The sketch you see here is what the actual playing area will look like (sorta). The bended lines are pipes running over the table. The goo river is also visible (beneath the metal construction). The idea was to put it all in different levels (each less than an inch high, so it wouldn't count as elevation). I plan on putting grated metal plates over the lower parts, so the different levels won't get in the way of playing a game too much.
Last part was making the wooden frames to later fit the foam in. As you can see, I went a bit haywire with my jigsaw. I wanted the table to look like just a small part of a big underground complex, with different caves connected to each other. That's why I cut the holes in the sides, to give people a feeling that things didn't stop at the edges of the table.
Also, I thought it would be cool to have people watching the game from these holes.
Finally, as you can se I made notes on the side of the sideboards. I am going to finish the side boards first and the do the central gaming area later. To do that though, I had to put markers on the side so I would know what would have to line up where once I start to put in the foam.
So, on to the next part: gluing and cutting foam.
If you have questions or would like to comment or make suggestions, I opened a new forum topic on the Privateer Press Forums. I'll try and post some more pictures over there and try to answer any questions you might have.


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Polycystic Kidney Disease Foundation Polycystic Kidney Disease Foundation
Here's a sample of our volunteer opportunities:VIEW AS
Mission Statement
The PKD Foundation is the only organization, worldwide, dedicated to promoting research to find a cure for polycystic kidney disease (PKD) and improving the care and treatment of those it affects. Our vision is that "no one suffers the full effects of PKD."
In 2007, the PKD Foundation will fund more than $4.2 million in vital PKD research and lobby the federal government for millions more. In addition to funding research, the PKD Foundation provides a forum for patients, family and friends through more than 70 volunteer-led Chapters across the country and the world and holds the annual Walk for PKD, held each year on the third weekend in September, and the National Convention on PKD, the only conference in the world for PKD patients and medical professionals.
This information
Might be out of date
Do you work for this organization?
Request administrator status and update its information!


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Yep 63 days today...... It baffles me that I wasn't able to to do this before...
I wish I could say I feel full of beans with lustrous hair gleaming white teeth and a glowing complexion, but I don't.... I still have zero energy, gum disease, insomnia (this is a new one in the last couple of weeks) and in absolute agony with Fibro/ME.......BUT.....I feel different, I feel proud of myself and happy in what I have achieved, the cravings have gone now, they are replaced with a fancying of a fag, they don't even need batting away it's just a shrug of the shoulders, you don't smoke Donna so get in with it I never intend going back to smoking, I am suffering at the moment, I'm not sure if that's unusual at 9 weeks or not? But I am hoping in a few weeks I will feel better... I must see some benefits soon, the only benefit so far is the extra money
*****alert question for the ladies men avert your eyes you delicate things*****
Ladies I must say this past week or so has been dire, do you find your PMT has got worse and lasts for longer since you quit? I am due on 9th but feeling really off since last week... :/


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So last night our new puppy decided my camera cord that was plugged into the USB port looked rather tasty. My boyfriend was on the computer when suddenly it stopped. Mouse, keyboard, everything just didn't work. Obviously he found the cable the dog ate and pulled it out. Tried to restart. Everything still has power, the fans in the tower work and all that jazz, the lights on the front come on, so he figures the motherboard got fried. So what I was wondering was, 1) Could the usb cord actually fry the motherboard, 2) if it can, could anything else be damaged, and 3) if I can just buy a new motherboard and plug it in and have it work.
Obviously I'm not super technical, ecspecially with hardware, and i'm not even 100% you can answer without seeing it. But i figured I'd ask for a better understanding of my situation before I call our computer friend over.
Thanks for any help you have.


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You most likely have heard how vitamin C is one of the major go-to sources for fighting illness, particularly the common cold. It can be found infused in many food items, cough drops and even beauty
In the daily laboratory battle to eradicate cancer, researchers from the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have recently traveled one step closer to more
It seems like news reports are constantly warning of the next big cancer threat from what you thought was a benign product. Currently, the new target is the dangers of one of the most innocent and trusted
Humans have made great strides in fighting all kinds of cancers, but it still is one of the leading causes of death worldwide. Changing your diet, exercising, taking supplements, reducing stress and
Chemotherapy can be a difficult process. In many cases it wreaks havoc on the entire system acting like a complete apocalypse, killing everything in its path.
It is an approach that some feel is too


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If you are running a modern business, you will need the most efficient and reliable access to a lot of information, which is why it pays to find out more about Metro Fiber Ethernet. Today, there is a lot of online content with much of it involving multimedia and which is radically different from conventional metro transport technology.This is in fact, the one network technology that is most widely used in the business world and almost every business is using Ethernet at its platform to converge data, internet, video and voice. The simple truth is that this option is able to address different needs such as Dedicated Internet Access, layer two networking and IP VPN Access.Metro Fiber Ethernet offers a very effective means of connecting remote local area networks (LANs) within a given metropolitan area and at good speeds. This is why it is a much better solution as compared to using private lines (dedicated), Frame Relay and even ATM.There are several good reasons to centralize your network servers at your company data center. Metro Fiber Ethernet helps you to connect your remote offices to all the necessary resources and in a manner that makes it seem like everything is available at your siteThis option is also good because it allows you to use high speed transmission and in addition allows you to scale you access to services that are hosted offsite.. It also allows you to obtain transport for backup, data storage and more. In addition, it also makes it easy for you to consolidate your storage systems.There are other pressing reasons why you should make use of this particular technology including the fact that it provides support for new and upcoming IP PBX systems that make use of these LAN technologies to connect different users in a corporate environment to the corporations phone system.It also provides a better solution than remote office connections. There is more to using this network solution than fiber cables because it also allows you to obtain numerous paths to any destination. This helps you to get the best possible service.A Metro Fiber Ethernet network is well liked because it is so reliable and yet at the same time offers agility to help you take care of requirements related to future network designs. It is being successfully used in many metros and can cover thousands of miles and there is also a lot of scope for future expansion.In addition, it also provides you with many benefits not least of which is that it helps in lowering costs. No modern business can afford to ignore it as it is a very cost effective and also very scalable way of connecting remote locations.It offers more benefits than the digital subscriber line or DSL options and is also better than T1 and even T3. You also have many options regarding how to use Metro Fiber Ethernet. It can for example be used as a pure such technology and also over SDH.The first option (pure Ethernet) is very inexpensive but at the same time is not too reliable and even scalability can be an issue. It is best used in a small environment. The SDH option is useful in any place where there is already an SDH infrastructure but it is not a very flexible solution.
Metro Fiber Ethernet,Metro Fiber,Fiber Ethernet,Metro Ethernet,Metro Ethernet Providers,Metro E


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|These valentine crackers are made with clean, recycled cardboard tubes, tissue papers, lace, tags and a bit of imagination.
These Valentine crackers are easy to make and also inexpensive, creative wrappings for Valentine sweets. Most folks wrap fancy paper around a tube, in this case I used a clean recycled toilet paper tube, tie off one end and then remove the tube before stuffing the wrapping with treats. Then they gently tie the opposite end shut. I sometimes leave the tube inside the wrapping in order to give the items inside a bit more protection from handling. These are usually set at a dinner party table, one per guest. At the end of the meal, the recipient pulls either end of the cracker to open the gift of small toys and or candy. Crackers originated in England and are most usually crafted during the Christmas holiday.
|One of the two Valentine crackers up close.
See More Cracker Crafts: the Christmas cracker link has a video demonstration.


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Read this tip to make your life smarter, better, faster and wiser. LifeTips is the place to go when you need to know about Hockey Positions and other Hockey topics.
Playing right wing is not as complicated as it sounds. Basically, you are like any other forward, trying to score goals and helping out the centerman. Always remember hard work in the corners.
I don't know, all I'm getting is that when your son is good at hockey and scores, your considered a "hog" and not a good hockey player. My son just turned 8 and scores. You will see him though standing on the ice to give other players a chance which is incorrect, but, hockey's not hockey anymore. If your not good, people talk about you --- if your good ---- people talk about you. you lose either way. I wish I could talk to my son differently, but I just don't know how. He's a scorer - not a hog. He's a solid, solid ice skater. He skates unbelievably. You can't knock him down. his stick handling has come into play unbelievably already. He lives and dreams hockey. He's in clinics all summer. He's in clinics during the season as well. loves it. I wish people would stop being jealous - it might make the game come back again and the kids have fun. I don't know what site I'm on --- I'm just venting and hopefully someone is listening.
A frustrated mother of a wonderful 8 year old who loves hockey and is a scorer.
|Guru Spotlight
|PJ Campbell


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Looking back on the 7th Academic Conference on Health IT Systems
January 7, 2013 in Medical Technology
The leading event in healthcare IT in Argentina and Latin America, which was held between the November 28-30 2012 at the Hospital Italiano in Buenos Aires was free and part of the annual program of the Hospital's healthcare IT department.
This edition attracted over 600 participants, 200 in person and 420 who registered online, meaning that the event had connections with over 15 countries, especially Chile, Peru, the USA, Colombia, Uruguay and Venezuela. With a record international attendance, participants were able to enjoy conferences and panels with world-renowned speakers such as Charles Friedman, Patricia Abbott, William Hersh, William Tierney, Judy Logan, Guilherme Del Fiol (USA), Javier Carnicero (Spain), and Andrés Fernández (Chile), amongst others. There was also significant representation from the region through 30 national and international panelists, mainly from the Southern Cone region (Argentina, Brazil, Uruguay and Chile). The awards handed out included a special recognition from FEMI (Medical Federation of the Interior of Uruguay) for the work of Fernán González Bernaldo de Quirós, Vice-Medical Director for Strategic Planning at the Hospital Italiano.
EHealth Reporter at the Event
"The presence of Ehealth Reporter as one of the only media outlets covering the events was very positive as it informed many professionals of the program in advance," said Dr. Analía Baum from the Hospital Italiano's health IT department. She added: "The objective for next year will be to add training workshops so those attending can get up to date with key issues such as HL7 computing, Introduction to Medical IT, etc. and also to add more local speakers in addition to professionals from other parts of the world." Also new this year was the presence of three recognized companies who accompanied the lunches, presenting new products that can help to improve the efficiency of healthcare processes.
These included Microsoft who gave the presentation "Windows 8 in a World of Connected Devices" and, on the last day, the company Inteligentia and Estanislao M. Irigoyen who spoke about "Analyzing Data Easily, Quickly and Intelligently." Another highlight was the exhibition presented by Dr. Alejandro Pazos (Spain) who together with his team of researchers at the Ibero-NBIC network, or the Ibero-American Network of Convergent Healthcare Technologies, financed by the Ibero-American Science and Technology Program for Development (CYTED), has conducted research into the social impact of Convergent Technologies; Nano-Bio-Info-Cogno (NBIC). In another field, the Association HL7 Argentina provided oversight and organization in order to promote the latest advances and discuss difficulties related to Digital Agendas in the Latin American region.
This story originally appeared at E-Health Reporter Latin America.
Article source: http://www.healthcareitnews.com/news/looking-back-7th-academic-conference-health-it-systems


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Two Antioch teens get the American Idol ticket to Hollywood.Mark DiMercurio | August 20th, 2015
Antioch was proudly represented last night on American Idol. Two teens were sent to Hollywood while doing their audition on the Queen Mary in Long Beach. Briana Oakley and Nicholas Crossen were both honored with the golden ticket. Briana is a junior at Carondelet High School and Nicholas is a sophomore at De La Salle High School. Briana's story was profiled due to the challenges of being bullied at a younger age. Good luck to both local singers as they move on to Hollywood. Attached is an article profiling Briana's story.


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Dr. Berler uses his comprehensive knowledge and diagnostic acuity to address disorders and diseases of the eye, especially retina and cataract problems. In addition to his private practice, he teaches and directs programs at numerous academic institutions throughout the Washington metropolitan area. He has been noted as one of our region's best ophthalmologists by Washingtonian Magazine on three separate occasions.
The New York Hospital, Cornell University Medical College, New York, NY, ophthalmology residency
Barnes Hospital, St. Louis, MO, medical internship
Cornell University Medical College, New York, NY, M.D.
Cornell University, Ithaca, NY, A.B.
Academic Appointments and Affiliations
Georgetown University Medical Center, clinical associate professor
Washington Hospital Center, Retina Service, senior attending surgeon
Washington Hospital Center, director of training and education
American Academy of Ophthalmology, fellow
Washington Academy of Ophthalmology, charter member
American Ophthalmological Society, member
American College of Surgeons, fellow
American Board of Ophthalmology


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National Water-Quality Assessment (NAWQA) Project
More Information about Nutrients
Nutrients National Synthesis
| Effects of Nutrient Enrichment on Stream Ecosystems | Sources, Transport, and Fate of Agricultural Chemicals
Sorted by: | Publication Date (newest first) | Publication Date (oldest first) | Author (A-Z) | Author (Z-A) | Title (A-Z) | Title (Z-A) |
Showing results 1 to 26 of 721.
Go to page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
Justus, B.G., Petersen, J.C., Femmer, S.R., Davis, J.V. and Wallace, J.E., 2010, A comparison of algal, macroinvertebrate, and fish assemblage indices for assessing low-level nutrient enrichment in wadeable Ozark streams: Ecological Indicators vol. 10, no. 3, p. 627-638. doi: 10.1016/j.ecolind.2009.10.007 Available Online
Ashbury, Clyde E., and Oaksford, Edward T., 1997, A comparison of drainage basin nutrient inputs with instream nutrient loads for Seven Rivers in Georgia and Florida, 1986-90: U.S. Geological Survey Water-Resources Investigations Report 97-4006, 8 p. Available Online
Alexander, Richard B., Johnes, Penny J., Boyer, Elizabeth W., and Smith, Richard A., 2002, A comparison of models for estimating the riverine export of nitrogen from large watersheds: Biogeochemistry, vol. 57, no. 58, p. 295-339. doi: 10.1023/A:1015752801818 Available Online
Bradbury, J.P., and Van Metre, P.C., 1997, A land-use and water-quality history of White Rock Lake Reservoir, Dallas, Texas, based on a sediment core: Journal of Paleolimnology, vol. 17, p. 227-237. doi: 10.1023/A:1007923829759 Available Online
Saad, D.A., Schwarz, G.E., Robertson, D.M., and Booth, N.L., 2011, A multi-agency nutrient dataset used to estimate loads, improve monitoring design, and calibrate regional nutrient SPARROW models: Journal of the American Water Resources Association, online 22Aug2011 in advance of print, 17 p. doi: 10.1111/j.1752-1688.2011.00575.x Available Online
Nolan, Bernard T., Ruddy, Barbara C., Hitt, Kerie J., and Helsel, Dennis R., 1998, A National look at nitrate contamination of ground water: Water Conditioning & Purification, vol. 39, no. 12, January 1998, p. 76-79. Available Online
McMahon, P.B., 2000, A reconnaissance study of the effect of irrigated agriculture on water quality in the Ogallala Formation, central High Plains: U.S. Geological Survey Fact Sheet FS-009-00, 6 p. Available Online
Garcia, Ana Maria, Hoos, Anne B., and Terzitti, Silvia, 2011, A regional modeling framework of phosphorus sources and transport in streams of the southeastern United States: Journal of the American Water Resources Association, 10 Mar 2011, online in advance of print, 20 p. doi: 10.1111/j.1752-1688.2010.00517.x Available Online
McMahon, Gerald and Roessler, Chris, 2002, A regression-based approach to understand baseline total nitrogen loading for TMDL planning: Proceedings of Water Environment Federation National TMDL Science and Policy 2002 Specialty Conference, Phoenix, Arizona, November 13-16,2002, 27 p.
Ator, S.W., Denver, J.M., Krantz, D.E., Newell, W.L., and Martucci, S.K., 2005, A surficial hydrogeologic framework for the Mid-Atlantic coastal plain: U.S. Geological Survey Professional Paper 1680, 44 p., and 4 maps. Available Online
McCarthy, K.A., and Capel, P.D., 2009, A whole-system approach to understanding agricultural chemicals in the environment: U.S. Geological Survey Fact Sheet 2009-3042, 6 p., on-line only. Available Online
Burkart, M.R., Kolpin, D.W., Jaquis, R.J., and Cole, K.J., 1999, Agrichemicals in ground water of the midwestern USA: Journal of Environmental Quality, vol. 28, no. 6, p. 1908-1915. Available Online
Kolpin, Dana W., 1997, Agricultural chemicals in ground water of the midwestern United States: Relations to land use: Journal of Environmental Quality, vol. 26, no. 4, July-August 1997, p. 1025-1037. Available Online
Kolpin, Dana, Hallberg, George, Sneck-Fahrer, Debra, and Libra, Robert, 1997, Agricultural chemicals in Iowa's ground water, 1982-95--What are the trends?: U.S. Geological Survey Fact Sheet FS-116-97, 4 p. Available Online
Waite, I.R., 2013, Agricultural disturbance response models for invertebrate and algal metrics from streams at two spatial scales with the U.S.: Hydrobiologia, 21 p. DOI 10.1007/s10750-013-1774-4. Available Online
Waite, Ian R. , 2014, Agricultural disturbance response models for invertebrate and algal metrics from streams at two spatial scales within the U.S.: Hydrobiologia (726), p. 285-303. DOI: 10.1007/s10750-013-1774-4 Available Online
Saad, David A., 2008, Agriculture-Related Trends in Groundwater Quality of the Glacial Deposits Aquifer, Central Wisconsin: Journal of Environmental Quality, vol. 37, p 209-225. doi: 10.2134/jeq2007.0053 Available Online
Calhoun, Daniel L., Gregory, M.B., and Weyers, H.S., 2008, Algal and invertebrate community composition along agricultural gradients: A comparative study from two regions of the Eastern United States: U.S. Geological Survey Scientific Investigations Report 2008-5046, 33 p. Available Online
Kent, Robert, Belitz, Kenneth, and Burton, Carmen A., 2005, Algal Productivity and Nitrate Assimilation in an Effluent Dominated Concrete Lined Stream: Journal of the American Water Resources Assocation, vol.41, no. 5, October 2005, p. 1109-1128. Available Online
Robertson, Dale M., Saad, David A., and Wieben, Ann M., 2001, An alternative regionalization scheme for defining nutrient criteria for rivers and streams: U.S. Geological Survey Water-Resources Investigations Report 01-4073, 57 p. Available Online
Munn, M.D., Black, R.W., Haggland, A.L., Hummling, M.A., and Huffman, R.L., 1999, An assessment of stream habitat and nutrients in the Elwha River Basin: Implications for restoration: U.S. Geological Survey Water-Resources Investigations Report 98-4223, 38 p. Available Online
Lee, C.J., Hirsch, R.M., Schwarz, G.E., Holtschlag, D.J., Preston, S.D., Crawford, C.G., Vecchia, A.V., 2016, An evaluation of methods for estimating decadal stream loads: Journal of Hydrology, in press, Available Online
Rupert, Michael G., 1994, Analysis of data on nutrients and organic compounds in ground water in the Upper Snake River Basin, Idaho and western Wyoming, 1980-91: U.S. Geological Survey Water-Resources Investigations Report 94-4135, 40 p. Available Online
Apodaca, Lori E., 1998, Analysis of ground-water-quality data of the Upper Colorado River Basin, water years 1972-92: U.S. Geological Survey Water-Resources Investigations Report 97-4240, 31 p. Available Online
Thiros, S.A., 2000, Analysis of nitrate and volatile organic compound data for ground water in the Great Salt Lake Basins, Utah, Idaho, and Wyoming, 1980- 98, National Water-Quality Assessment Program: U.S. Geological Survey Water-Resources Investigations Report 00-4043, 20 p. Available Online
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text:
The turtles are coming… The turtles are coming!
Giant fiberglass sea turtles are coming to Topsail Beach!
Artist Jane Shaar started the fund-raising project. Like in many cities, artists in Topsail will paint large sculptures get local businesses to sponsor them. Naturally, the sculptures on Topsail Island will be of sea turtles. Next fall, the turtles on display will be auctioned off.
Shaar is working on the first turtle, named "Starry Night", inspired by Van Gogh's famous painting.
"It's extremely rewarding and I've found some wonderful people to help me out. Surf City Art's Guild has been great, some of the turtle people I know from Turtle Patrol, they're helping out, so it's just kind of bringing us all together, and everybody loves the sea turtles, you know it's just a given," said Shaar.
All of the money raised at the auction will support the expansion of the Karen Beasley Rescue and Rehabilitation Center in Topsail Beach.
Story image
Story summary
Giant fiberglass sea turtles are coming to Topsail Beach!
Story summary image
Associated poll
More: continued here


text:
A Balinese Folktale: Protector of Tenganan
Once upon a time there was a man named I Tundung. Because he was very poor, he had no place to live. He wandered from one place to another. As for food, he depended upon the mercy of the people in the neighborhood.
One day after having walked for some time he arrived at a village called Tenganan. He was starving since he had not eaten anything from early morning. He walked slowly until he arrived at a house. The house belonged to the village's chief, Jero Pasek Tenganan. He then asked: Who are you and where do you come from?" I Tundung answered: "My name is I Tundung, I have no place to live. I move from one place to another and get my food from the people."
Jero Pasek Tenganan was moved by what the man said. He then provided him with some food and drink after having eaten the food I Tundung then said: "Jero Pasek, if you do not mind starting from now on I would like to serve you." Without giving much thought Jero Pasek accepted the offer. "All right Tundung, you can stay in my house." From then on I Tundung served Jero Pasek. He was very diligent and honest. This pleased Jero Pasek so much.
One day, Jero Pasek summoned I Tundung. "Tundung, I am very pleased with what you have shown. You are very diligent. I want you to farm the land at the East Hill. Now the land is neglected. Nobody is there to farm it." I Tundung listened attentively to what Jero Pasek said. As he wanted to have work to do, he then said: "All right, Jero Pasek, I will do my best."
Soon I Tundung moved to the land at East Hill. There he built himself a hut. He toiled the land for the crops. In the end his hard work was fruitful. The crops were abundant. Jero Pasek was munch impressed by I Tundung's effort. But, alas, a disaster then crept. The yields of the crops were stolen. This had made Jero Pasek disappointed. "Tundung, there have been thefts lately. You might have become frustated because of these." I Tundung responded: "Please forgive me, Jero Pasek. I do not want to leave the job you have trusted to me just because of the thefts." I Tundung kept watch day and and night, but he could not stop the thefts. Jero Pasek was in despair and I Tundung knew about it. He felt ashamed of himself.
Once day at night I Tundung went to offer his prayers at a shrine, called Naga Sandung, which is located is the middle of the land. He made a request to the gods for protection. He then heard a voice from the sky. "Tundung, my son, your wish is granted on one condition. You have to be transformed into a black snake". In his mind I Tundung said that he would do whatever the gods wished as long as he could serve Jero Pasek. Soon he could feel his neck and body become longer and turned into a big black snake.
As usual Jero Pasek visited I Tundung at Bukit Kangin. When he arrived at the hut he could not see I Tundung there. He looked for him everywhere but is what useless. I Tundung seemed to have disappeared. Jero Pasek then went into the shrine. There he was welcomed by a huge black snake. "Jero pasek Tenganan, I am I Tundung who has changed into a snake. I fell ashamed because I am not able to stop the thefts. From now on I am going to guard your property more effectively. Nobody will dare to steal the crops." Jero Pasek responded: "Tundung, you are really a faithful servant. I have no doubts in your faith. Please forgive me."
From that very day I Tundung and his descendants have kept guard on the farming land in Tenganan. No more thefts took place. The snake are now known as Lalipi Selem Bukit [ The Hill Black Snake ] which the people in Tenganan and its surroundings believe that the snake still live in the bushes of the villages.


text:
Been a while i didn't post anything on the blog !
Here are some related-music news :
Next release from me is Night Dive and Dedale on the flip, a collaboration with Headhunter on his brand new label called Transistor (www.myspace.com/transistorrecordings). The record should land in your shops really soon now. Watch out for that one !
Massive shouts to Tony Headhunter !
I also did a remix of Jus Wan's Azure for Pushing Red Recs, a new label sets up by Heath from Warm Communications (a high quality drum'n'bass label for those who don't know).
This will be on the third release of the label, backed with a huge Headhunter remix of Avoid the Noid by DJG.
Also Jus Wan and i have been working on collab tunes, one called 'Reason To Live', the other is not finished yet. More infos soon.
And last but not least Im putting the final touch on my debut album called "Energy Distortion" which will be out on 7even Recordings next year.
Looks like there will be one sampler (with a remix by a very talented producer), 2 double packs and a CD with 12 tracks including exclusives tracks on both format.
Cheers !
Have a nice day,
vendredi 2 octobre 2009
1 commentaire:
- Anonyme2 octobre 2009 à 07:59
Huge man!!RépondreSupprimer
Can't wait to hear that!!
Take care
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text:
Ujjain: A day after stating that the
Prime Minister and Chief Justice of India should not be
brought under the ambit of the proposed Lokpal Bill, Yoga Guru
Baba Ramdev on Wednesday did a volte-face saying he did not make
such a statement.
He also said that he was firm on going ahead with his
planned indefinite fast against corruption in Delhi from June
4, despite government`s requests to put off the fast.
"I did not say that the proposed Lokpal Bill should not
cover the Prime Minister and CJI as their posts are highly
dignified," Ramdev told reporters after ending his one lakh km
Bharat Swabhiman Yatra here.
"Keeping the PM and CJI out of the Lokpal`s ambit was
never my personal opinion," he said, adding that there were
talks in the public that these posts should not come under the
ambit of Lokpal bill.
Ramdev said in Madhya Pradesh`s Sehore district
yesterday that the Prime Minister and CJI should not come
under the ambit of Lokpal given that these posts were highly
Baba also praised the CJI, saying that the judiciary in
the country was very active.
When asked to comment on Anna Hazare`s statement praising
the Prime Minister, he said he was not a spokesman of the
anti-graft crusader. "We are companions," he said.
He said that even though the government representatives
were urging him to put off his proposed fast, he would go
ahead with the fast. A meeting of our people is taking place
over the fast in Delhi, he said.
"I want that the huge black money stashed in foreign
banks should be brought back to India. I want to free the
country of corruption", he said.


text:
A team of staff from Fittleworth Medical are celebrating after crossing the finish line at a fundraising challenge.
Justin Lanchbery, Paul Clarke, and Andy Hall were among other walkers and runners showing their support for Worthing based hospice St Barnabas House by taking part in the South Downs Trek.
The 12 strong Fittleworth Medical team joined one hundred other fundraising champions to brave the wet and windy conditions on the South Downs on Saturday, October 7.
The Fittleworth Medical team, comprised of members of staff from the UK based home delivery companies which specialises in Stoma, Continence, Wound Care and Spinal Injury products, was the first team of walkers to cross the finish line with a time of five hours and 30 minutes.
The South Downs Trek, now in its third year, is expected to raise around £30,000 for the charity, which will go towards funding vital hospice care services for adults with life-limiting illnesses across the local area.
This year was the first time that the annual event has been opened up for runners to take part in addition to walkers.
The first person to cross the finish line at St Barnabas House was Ian Thompson, 40, who completed the run in 3 hours and 40 minutes.
Ian, who often competes in triathlons, said: "My mother-in-law, Linda Keenlyside, was looked after by St Barnabas so I thought it was a fitting way to do something in memory of her. It was a challenge. I've not done any distances over 25km so it's the longest I've run as well. There were a few cheeky little hills, especially the one after Washington and the one near the end after the tunnel. There was a crosswind and drizzle which was quite a challenge too, but enjoyable. My kids and wife joined me at four or five points along the way and they ran with me. The kids normally cross the finish line with me at the races I do. It was a really good day, even though the weather was challenging, and I'm so grateful for all of the volunteers as well. It's a good event and hopefully we'll have more runners taking part next year."
Ian has raised over £560 in sponsorship. Sponsor him by making a donation via his JustGiving page: www.justgiving.com/southdownstrek2017
Lucy Bone, events fundraiser at St Barnabas House, said: "Despite the weather our 100 runners and walkers thoroughly enjoyed the event and we are expecting it to raise around £30,000 for the hospice which is a fantastic amount. I would like to say a big thank you to everyone who took part as well as our amazing volunteers who spurred on the walkers out on the route and helped with various different tasks at the start and finish line.
Soon after first place challenger Ian crossed the finish line he was joined by fellow runners Justin Burt and Kelly Barnard, a keen runner who has also competed in the Brighton Marathon and Brighton Half Marathon to raise money for St Barnabas House.
Kelly, 32, has a close personal connection to St Barnabas House after her dad, Brian Barnard, received care at the hospice while battling with kidney cancer.
Kelly said: "It was enjoyable and tough running it, but good fun and I enjoyed it. It was very windy. It was nice when you were welcomed by the checkpoints. Everyone was very cheery. It's lovely to see everyone from all walks of life come together to raise money for an amazing charity. People should be proud for doing that."
Kelly has raised over £3,700 for St Barnabas House by taking part in various running events and asking friends and family to sponsor her. Her JustGiving page can be found at www.justgiving.com/barneyrunsforbarnabas.
Many walkers were taking part in memory of loved ones who have been cared for by St Barnabas House, including team 'I could do with a brew' which consisted of Sarah Homewood, Simon Whiting, Karen Dunn, Ian Oakley and Phil Whiting.
Sarah said: "We did it in memory of our mum, Lynn Whiting. She had lung cancer and St Barnabas helped her and cared for her in her last week. They were fabulous. They cared for her and it meant we could spend her last few days with her. We wanted to be able to give something back because they did such a fabulous job and you feel so helpless. We saw this challenge and decided to give it a go. We've beaten our targets and done really well with our fundraising. It's a massive goal achieved. I'm glad I did it with my friends and family. It was just a great experience all around and I would recommend it to anybody thinking of doing it, but put in the preparation beforehand!"
Between them the 'I could do with a brew' team have raised over £1,800. Sponsor them at www.justgiving.com/companyteams/Icoulddowithabrew.
Registration is still open for the Dalia Lama India Trek for St Barnabas House which takes place in October 2018. For more information, or to register a place on the trek, visit www.stbh.org.uk/india.


text:
Alma Mater
To thy precepts and thy aims
We'll love thy glorious guiding light
And pledge anew our love.
We'll fight for thee where ev'r we go
Thy glories ne'er forget
We'll keep thy standards flying high
In all we do or say.
The flag of truth and honesty
We'll wave e'er all the land
Till all thy Sons and Daughters know
Thy precepts strong and true.
For S.B.S. We'll give our all
For S.B.S. We'll stand
We'll always hold our honor high,
For Dear Old S.B.S.
"Together, We Can Make A Difference"
© Scott's Branch High Alumni Association 2012
Alumni Association, Inc.
Post Office Box 1374
Summerton, SC 29148
Phone: (803) 897-3417
Fax: (803) 897-3417
|Scott's Branch High
Alumni Association, Inc.


text: Hi Steve, Such a thing most definitely exist, at least for protein sequences. I'm not sure exactly what you are looking for because you ask for the assessment of _nucleotide_ multiple sequence alignments, yet below you gave an example for protein multiple alignments. Either way, type Poch O or Thompson JD (better yet, both) into PubMed and you will have plenty to read. In particular, look at articles with PMID numbers 11734009 and 12801878 or just type "norMD align" into any search engine. SAM ( http://www.soe.ucsc.edu/compbio/sam.html ) has a function that improves the existing alignments of _protein_ sequences while removing unrelated entries, but it is fairly slow. Finally, if you are looking only for nucleotide alignments, as stated, I suggest you contact the experts directly - Oliver Poch and Julie Thompson certainly come to mind. Best regards, Mensur At 04:32 AM 7/27/2007, you wrote: >Content-class: urn:content-classes:message >Content-Type: multipart/alternative; >boundary="----_=_NextPart_001_01C7D039.5E9D2F84" > >--> > >Is this list still active? Ive not heard anything here since the end of >last year, but hey maybe we all know what we need and have kept quiet. > > > >Serious question: > >Is there an algorithm / method / program or server that can assess the >quality of a nucleotide multiple sequence alignment (generated by a >progressive clustering algorithm e.g. Clustal), without the need for a >reference alignment? > > > >Ive come across several papers & servers via Google & PubMed but all need >reference alignments or are for protein sequences where structural >information is available. The closest so far is by Ahola et al >(<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1687212>http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1687212), >which looks great until you reach the end of the alignment quality section >of the methods and find the sentence By comparing the ConsAAs calculated >from the test and reference alignments . > >The ability to bootstrap trees generated from alignments is already well >established and Id like to get some thing that examines the alignment >more directly. > > > >What Im really looking for is a method that I can apply directly to the >alignments generated by our users that is better than a simple set of >column conservation scores across the alignment but Im starting to >think that such a thing does not exist. > > > >Any advice would be helpful. > > > >Steve > > > >Bioinformatics Unit: Statistics, Modelling & Bioinformatics Department > >Center for Infections > >Health Protection Agency > >London > >UK > ><http://www.hpa.org.uk/cfi/bioinformatics/index.htm>http://www.hpa.org.uk/cfi/bioinformatics/index.htm > > >_______________________________________________ >ssml-general mailing list >ssml-general at bioinformatics.org >https://bioinformatics.org/mailman/listinfo/ssml-general ========================================================================== | Mensur Dlakic, PhD | Tel: (406) 994-6576 | | Department of Microbiology | Fax: (406) 994-4926 | | Montana State University | | | 109 Lewis Hall, P.O. Box 173520 | http://myprofile.cos.com/mensur | | Bozeman, MT 59717-3520 | E-mail: mdlakic at montana.edu | ==========================================================================


text:
Andre Sideboard
The Lillian August Modern Living Andre Sideboard With An Oak Case And Grey Amate Doors With Aged Brass Hardware Is Sure To Be A Show Stopper.
Product Specifications
- Dimensions
- Depth: 18 Width: 68 Height: 35
- Lead Time
- 4-6 Weeks
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About Lillian August
With over 30 in-house interior designers, four showrooms, unlimited trade resources and an unprecedented selection of quality products, as well as licensed furniture collections, Lillian August is the premier one-stop resource for design.
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text:
Boots & hangs - replaced thermal grease - no joy
I have an a1055. It boots and hangs after a minute or so when cold. When warm, it will boot to a blue screen after the gear and hang.
I saw recommendations of replacing the thermal grease. I did that but it did not improve the problem. I really think this is a heat issue as I was able to pursued it to re-format and install the os by having it sit on a cold pack.
I have a couple of question:
1- when I got inside, I found that it used the heatsink material, like foam, instead of thermal paste. Would using thermal paste provide enough contact to dissipate the heat? Do I need to find more of the heatsink material instead?
2- any ideas what might still be wrong? I am not certain the fan is working. I think I hear it when it boots, but it seems to shut down after initial post . . . I think. It's hard to tell for certain when everything is coming on at power up.
Is this a good question?


text:
- "Aye, they're comin'!"
- —Gordon
Gordon is a character in Brave.
He is seen along with Martin at the main door to the Great Hall of the castle and he announces the arrival of the Lords until he gets slammed by the door before he could finish. He assists King Fergus into killing a bear in the castle unaware it is Queen Elinor until they were stopped by Princess Merida. He also attempted to attack Mor'du, but the giant bear proved to be too powerful for him. However, he survived like everyone else.
- This is one of John Ratzenberger's least recognizable Pixar roles because he speaks with a Scottish accent in the film.


text:
CAT Driver Training owns and maintains our own fleet of track training vehicles, offering the following configurations: FWD; FEFWD; FERWD; MERWD; and 4WD. It is also possible to hire in additional training vehicles (at extra cost) if you have a specific requirement.
Our Subaru Impreza
Vehicle Specification
2000cc Modified to deliver 310BHP
- Oil cooler
- 6 speed gear box
- Competition clutch
- Lightened flywheel
- Remapped
- Modified cylinder heads
- Modified exhaust manifolds
- Modified exhaust system
- Adjustable dampers & springs
- Modified anti roll bar links
- Circuit geometry settings
- Goodridge brake hoses
- Competition brake fluid
- DS 2500 brake pads
- 6 point roll cage
- Competition seats
- Full harness seat belts
- VBox Data logging
- Plumbed in fire extinguisher
- Hand held fire extinguisher
Our Nissan 350z
Vehicle Specification
Make: Nissan
- Model: 350z
- Colour: Silver
- Engine size: 3.5ltr
- Fuel Type: Petrol
- Engine/Drive train: RWD
- Tyres: Avon ZZ5
- Brakes: Upgraded pads, fluid & Goodrich brake hoses
- Additional Modifications: Fire extinguisher
Our 'Drift' Caterham 7
Vehicle Specification
Make: Caterham 7 Super Sport
- 6 Speed Gear box
- 1.6 K Series
- Throttle Bodies
- Upgraded Cam shafts
- Anti-Cavitation Tank
- Competition Clutch
- Alloy Radiator
- Wide track Front Suspension
- Dedion Rear Suspension
- Bilstein Dampers
- Limited Slip Differential
- Clubman Roll Cage
- Plumbed in Fire Extinguisher
- Quick Release Steering Wheel
- Lowered Seats
Our BMW 3 Series
Vehicle Specification
Make: BMW
- Model: 3 Series 330D saloon
- Engine size: 3ltr
- Fuel Type: Diesel
- Engine/Drive train: RWD
- Tyres: Bridgestone
Our Road Standard Ford Mondeo
Vehicle Specification
Make: Ford
- Model: Mondeo
- Specification: Black
- Engine size: 2ltr
- Fuel Type: Petrol
- Engine/Drive train: FWD
- Tyres: Avon
- Additional modifications: Hand held fire extinguisher
By design this vehicle is unmodified, all components are standard and Ford part numbered. Prepare to be amazed at what you can achieve in a standard vehicle.


text:
You can view the trailer here.
I've also been working hard on multiple other projects, being a mom, etc, etc… I know. Cry ya a river. We're all friggen busy.
In any case, I've been getting back up to speed (once again - thanks Lesley!) with the running. I've been quietly getting up extra early, putting in my miles and just doing it. Today I only did 4 out of 6 because I didn't get up early enough so I'll make those up.
Cupcake Marathon this weekend - I am sending the positive vibes into the universe that I win the spibelt - I need one, money is tight and the leather fanny pack I've been using just isn't cutting it- LOL. Coach Lesley has me down to run a 12 miler on Saturday but I'm going to go for 13 so I get my virtual 1/2 marathon in! Jason's rules allows us to break up the run but I figure, "eh, why do that?" I'm arunnin' it straight.
And speaking of coach Lesley - I've got a new roomie for San Diego! Lesley from Racing It Off and Sherry (my newest blog follower - hi Sherry!) Have extended an invite for me to shack up with them for the SD RNR marathon in June. I'm excited and think it's going to be a great weekend. (Although I'm in a panic about being properly prepared… I'm just doing my best, doing my best…)
And (thanks Nik) today's RunnersWorld quote from Jeff Galloway says:
"The more you frame the marathon as a stressful experience, the more negative messages you'll receive. But it's just as easy to frame it as a positively challenging journey."
And more inspiration comes from this Jack Canfield blog post I read today, entitled, "The Power of Determination." Feeling a little uncertain and very "off" lately and this read really struck home.
I would encourage you to read the post, it's a quick read but I especially loved what he had to say about adversity:
Adversity and Discouragement Is Inevitable
No matter how well you plan and how well you execute your plan, you are bound to meet with disappointments, setbacks and failure along the way to your ultimate triumph...
...The longer you hang in there, the greater the chance that something will happen in your favor. No matter how hard it seems, the longer you persist, the more likely your success will be.
As Confucius wrote more than 4000 years ago in China, "Our greatest glory is not in never falling, but in rising every time we fall."
Hope you all are doing great - what's going on with you?