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Leadership begins with mindset. What is mindset you may ask? Mindset refers to the ideas, beliefs and attitudes with which a leader approaches a situation. Thus mindsets are the foundation of great leadership, as mindset forms the basis for action.
The VUCA environment of today is rewriting the rules of business. The result is that leaders desperately need new mindsets and new ways of looking at the world. Consider the cause of some of the biggest leadership failures of the past decade:
- Kodak created the first digital camera, an 8 pound, 0.01 megapixel still camera, in 1975. Despite Kodak's technical innovations – which were numerous – Kodak failed to adapt to the new digital world. In February 2012, Kodak announced that it would cease making digital cameras.
- Blockbuster was an American provider of home movie rentals through retail shops. The company later added DVD-by-mail, streaming, video on demand and cinema theatre. Blockbuster at it's peak in 2004, had up to 60,000 employees and more than 9,000 stores. However, Blockbuster failed to adapt to changes in it's environment and respond to competition from the likes of Netflix. On April 6, 2011, the company and its remaining 1,700 stores were bought by satellite television provider Dish Network at auction for $233 million.
- Borders Books was an international book and music retailer. The company employed about 19,500 staff in its Borders and Waldenbooks stores. Borders too failed to respond to a changing environment and increased competition. On July 7, 2010, Borders opened an eBook store to allow books to be directly downloaded to an e-reader. But, It was too late. On February 16, 2011, Borders applied for Chapter 11 bankruptcy protection and began liquidating 226 of its remain stores in the United States.
These companies did not fail due to a lack of technical know-how. Each of these companies had the necessary leadership skill set. So what happened?
The failure of these companies was due to the lack of an effective leadership mindset. What derailed the leaders of these organisations was the combination of a changing environment and a mindset that was stuck in the past. The shift in their industries toward digital required new mindsets, new ways of seeing, and new ways of being. They needed new maps to navigate their organisations into the future. These leaders failed to shift their mindset as required to compete in the new business environment.
"Unfortunately, top people are often there because they are expert in what was important yesterday… We put more energy into developing skill sets, rather than the right mindsets" – Professor Jonas RidderstrÅle, Stockholm School of Economics
Past success and outdated leadership mindsets are the biggest inhibitors of future success.
Leadership is not about the how – the skills of leadership. The skills of leadership will only get you so far. In business today, leaders need to focus as much on the development of their mindset, as they do on the development of skillets. Organisations desperately need new visions and new maps to navigate by.
Too many organisations are busy with the tasks of yesterday. Leaders need to stop doing the tasks of the past and make way for the new.


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Climate Change: What's next for Egypt?
In a year that has seen the force of nature wreak devastation in several parts of the world, including Bangladesh, the Caribbean, and Mexico, the big issue of this generation—climate change—was the topic of a Chevening Talk held by British Embassy Cairo.
The event, which focussed on the greatest environmental challenges facing Egypt at the moment, brought together expert Cheveners in the environment field from diverse backgrounds, including civil servants, UN and World Bank employees, academics, researchers, architects, and businesspeople. It was part of the 'Chevening Discussion Series of Egypt', a series of thematic discussions with alumni to provide a forum where they can openly debate issues, and share their knowledge and expertise in key areas. Chevening Alumnus Saber Osman, Climate Change Adaptation Manager at the Egyptian Environmental Affairs Agency, co-moderated the discussion.
Prevention or adjustment?
The main argument of the talk revolved around whether Egypt as a nation should prioritise issues of mitigation or adaptation to climate change. Participants argued that one major issue getting in the way of Egyptian action on climate change was a lack of awareness—companies do not follow environmental regulations because they do not understand them. Another issue was the lack of incentives for changing behaviours. Other participants argued that as climate change is not going to be reversed, Egypt is in dire need of adapting to it. However, the challenge of adapting is the hefty costs of investing in the adjustment of existing infrastructure. Could there be low-cost solutions to help with adaptation? This question must be common in many countries around the world.
Making a case for real evidence, to challenge the fake news
The other significant conversation was around the importance of encouraging relevant research and finding ways to encourage the Egyptian government to engage with research. The debate centred around whether there was a lack of research on relevant issues, or that existing research was not communicated to or used by the government.
The UK's role?
The lively discussion wrapped up with some interesting ideas about what the UK could do to help including:
- Raise awareness by lobbying for better coverage of environmental issues in Egyptian education, or by using an Inspire Egypt event to draw attention to environmental issues.
- Support rising start-ups in the environment field, potentially through the embassy's £2M start-up fund.
- Encourage research on environmental issues via scholarships and help to create a repository of relevant Chevening dissertations.
- Continue to facilitate discussions among experts in this area since there was a strong appetite for further interaction.
- DIT seeking to encourage UK investment in key areas.
- Lobby on environmental issues with Egyptian decision-makers.
The talk left attendees with a huge appetite to discuss other relevant topics like waste management, renewable energy, and water issues in the future.
It was a stimulating session for all with one attendee commenting that 'it was a very interesting event and moreover, it was great to see Cheveners from different years of the same field networking and exchanging contact details.'
To find out more or to attend the next event, contact Nevine Sharaf, Chevening Programme Manager at British Embassy Cairo.

subset: commoncrawl


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The International Film Festival of Contis is finish. It was so fun to see you guys enjoyed the movie and watch it on DCP on big screen !
You'll can see some photos of the festival on the Facebook page of Alfred very soon.
By the way, the french newspaper Sud-Ouest wrote an article about the festival and talk about us ! You can read it here.
Now Alfred has cross the ocean again, and from september 20 to 25, he will be in competition during the Twin Cities Film Festival in Minneapolis, USA.
See you soon for more news about the movie !


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About University
Acharya Nagarjuna University, a state university established in 1976, has been constantly striving towards achieving progress and expansion during its existence for over three decades, in terms of introducing new courses in the University Colleges, affiliated colleges and professional colleges. Spread over 300 acres of land on the National High Way (NH-5) between Vijayawada and Guntur of Andhra Pradesh, the University is one of the front ranking and fastest expanding Universities in the state of Andhra Pradesh. The university was inaugurated on 11th September, 1976 by the then President of India, Sri Fakruddin Ali Ahmed and celebrated its Silver Jubilee in 2001. The National Assessment and Accreditation Council (NAAC) awarded B++ grade (80 85 Points) to Acharya Nagarjuna University.
It is named after Acharya Nagarjuna – one of the most brilliant preceptors and philosophers, whose depth of thought, clarity of perception and spiritual insight were such that even after centuries, he is a source of inspiration to a vast number of people in many countries. The University is fortunate to be situated on the very soil where he was born and lived, a soil made more sacred by the aspiration for light and a state of wholesomeness by generations of students.
With campus student strength of over 5000, the University offers instruction for higher learning in 50 PG programs and guidance for the award of M. Phil and PhD in 48 disciplines spread over six campus colleges and one PG campus at Ongole. It also offers 153 UG programs in 412 affiliated colleges in the regions of Guntur and Prakasam Districts. It has a Centre for Distance Education offering 87 UG & PG programs. Characterized by its heterogeneous students and faculty hailing from different parts of the state and the country, the University provides most hospitable environment for pursuing Higher Learning and Research. Its aim is to remain connected academically at the forefront of all higher educational institutions.
The University provides an excellent infrastructure and on-Campus facilities such as University Library with over one lakh books & 350 journals; Computer Centre; University Scientific Instrumentation Centre; Central Research Laboratory with Ultra modern Equipment; Well- equipped Departmental Laboratories; Career Guidance and Placement Cell; Health Centre; Sports Facilities with Indoor & Outdoor Stadia and Multipurpose Gym; Sports Hostel; Separate hostels for Boys, Girls, Research Scholars and International Students; Pariksha Bhavan (Examinations Building); Computers to all faculty members; WiFi connectivity to all Departments; Canteen, Student Centre & Fast-food Centre; Faculty Club; Dr. H.H. Deichman & Dr. S.John David Auditorium cum Seminar Hall; Post Office; Telecom Centre; State Bank of India; Andhra Bank; Energy Park; Silver Jubilee Park; Fish ponds; Water harvesting structures.
The salient features of the University are:
- Recognised by University Grants Commission (UGC), Association of Indian Universities (AIU), Ministry of HRD, and Government of India.
- It is an autonomous State University.
- Funded by the University Grants Commission (UGC) and Government of Andhra Pradesh
- Accredited by NAAC in 2003 and 2010.
- It is an Affiliating University with over 412 P.G.,U.G and professional colleges.


text: Planning, Managing and Publishing Research > Collaboration > Behind the Science Free Behind the Science | September 01, 2013 Using Collaborations to Strengthen Research and Work Smarter Faith Akin Author Affiliations & Notes Faith Akin VA Medical Center, Mountain Home, Tenn. & East Tennessee State University The content of this page is based on selected clips from a video interview conducted at the ASHA National Office. The content of this page is based on selected clips from a video interview conducted at the ASHA National Office. × Copyright © 2015 American Speech-Language-Hearing Association Article Information Balance & Balance Disorders / Research Issues, Methods & Evidence-Based Practice / Professional Issues & Training / Planning, Managing and Publishing Research / Collaboration Behind the Science | September 01, 2013 Using Collaborations to Strengthen Research and Work Smarter CREd Library, September 2013, doi:10.1044/cred-col-tth-001 CREd Library, September 2013, doi:10.1044/cred-col-tth-001 View Article Figures Tables Supplemental Data Supplements Multimedia Share Email Twitter Facebook Pinterest Tools Get Citation Citation Akin, F. (2013). Using Collaborations to Strengthen Research and Work Smarter. CREd Library, 4(1), . doi: 10.1044/cred-col-tth-001. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager © 2018 American Speech-Language-Hearing Association × Alerts User Alerts You are adding an alert for: Using Collaborations to Strengthen Research and Work Smarter You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account The alert will be sent to: Confirm × Sign In or Create a free account to receive alerts. × I think it's stronger when you have an interdisciplinary approach. We have a fairly active vestibular balance lab. There are four investigators that collaborate on research experiments. One physical therapist and three PhD audiologists. I guess what I've become really aware of is the contribution that other fields can bring to the patient, to care for the patient, and the research question. If we are just approaching it from the way an audiologist might approach it, the patient is not as well served, and I think the research question is a little narrower than it would be than if you had other fields -- like physical therapy -- working with you. I mean, you could also add psychology, otolaryngology, neurology, other fields as well. What are some of your "lessons learned" from collaboration? I think the one thing that we try to do in our lab is to kind of source out some of the components of our work. If you need somebody to develop a database, for example, we're not going to spend a lot of time ourselves developing that database. But we get somebody with expertise in that area. So we've tried to work more efficiently -- that's helped us be a little bit more efficient than if we were doing all of those components ourselves. I think we've gotten smarter about that. Several years ago -- or even more recently than that -- we've been working with an aerospace engineer at East Tennessee State University to help us with some data analysis and some instrumentation. Initially we'd spent a lot of time ourselves in the lab trying to fix that and figure out the answers to that. When we started collaborating with other people that had this expertise, I think we became more efficient -- that made a lot more sense -- and I think we've tried to use that model. Rather than trying to figure out that answer ourselves, we go look for collaborators. That just adds strength to your project. You're thinking about it in different ways, you're approaching the problem in a way that you probably wouldn't have otherwise. That's probably one of the more important lessons that I learned out of error from doing it the wrong way myself for too long. Related Articles International Research Collaborations: The Process and Its Benefits SIG 17 Perspectives on Global Issues in Communication Sciences and Related Disorders, May 2012, doi:10.1044/gics2.1.32 Ethical Considerations for Clinical Research Collaborations SIG 11 Perspectives on Administration and Supervision, October 2008, doi:10.1044/aas18.3.77 Prologue: Developing Evidence-Based Practices and Research Collaborations in School Settings Language, Speech, and Hearing Services in Schools, July 2001, doi:10.1044/0161-1461(2001/013) Epilogue: Developing Evidence-Based Practices and Research Collaborations in School Settings Language, Speech, and Hearing Services in Schools, July 2001, doi:10.1044/0161-1461(2001/018) Collaborating With Small Business to Fund Your Research SIG 4 Perspectives on Fluency and Fluency Disorders, November 2009, doi:10.1044/ffd19.3.90 Related Topics Balance & Balance Disorders Research Issues, Methods & Evidence-Based Practice Professional Issues & Training


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I actually found this recipe while looking for another. My husband loooved it! Plus it only cost me around $6 to make. I have left off the jalapenos before, and I have also substituted the tomatoes and bell pepper with rotel. Instead of bisquick I have used pizza dough (it was a lot cheaper that way).
John Wayne Casserole
2 lbs ground beef cooked and drained
1 pack taco seasoning
4 oz sour cream
8 oz shredded cheese divided in half
1 yellow onion chopped
1 chopped tomato
1 green bell pepper chopped
jalapeno peppers (slices)
4 oz mayonnaise
2 cups bisquick
Preheat 325°. Cook beef, drain, and add taco seasoning according to package. In a separate bowl combine sour cream, 1/2 the cheese, 1/2 the onion and mayo; set aside. Mix bisquick (according to the directions) and add to the bottom of a greased 9×13 casserole dish. Saute remaining onion & bell pepper until soft. On top of bisquick add meat, tomatoes, bell peppers and onion, jalapenos, sour cream mixture, and top with remaining cheese. Bake 30-40 minutes until edges are lightly brown.


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There were also an unprecedented number of students who achieved at least five A*/As including:
Rose Schoolland, who will study biology, maths, further maths, chemistry and physics at A' Level, achieved 11 A/A*'s and said "I had an amazing relationship with all of the teachers. They pushed and pushed to get more from me and I always felt encouraged to do my best".
Sophie Heath and Ellen Teesdale achieved 9 A/A*'s apiece. Sophie will be joining the RPA sixth form to study history, English, psychology and maths. "The English extracurricular work run by Mr Potapov really helped in getting the best out of me. It wasn't just about passing exams; it was a real education." Ellen, who will study biology, chemistry and history at A level commended all the teachers with a special mention to Head of Humanities, Mr Cook, whose "encouragement throughout five years made a huge difference".
Twins Mahmood and Mustafa Gabr achieved 13 A/A* between them and commented on the helpful and supportive teachers with particular reference to the "amazing" Saturday School revision programme. They now go back to Egypt to study physics, maths, further maths and chemistry.
Lesley Kirby, RPA's Headteacher, comments, "These are results to be proud of. Students and staff should be congratulated for the tremendous work they put in to secure some outstanding outcomes. Everyone at RPA remains committed to building on this year and ensuring that all of our students reach their potential in the years to come".


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There are a number of reasons why The processing of Group Policy failed error could happen. When you try to run gpupdate /force you receive the following error:
User policy could not be updated successfully. The following errors were encountered.
The processing of Group Policy failed. Windows attempted to read the file \\domain.local\SysVol\domain.local\Policies\{Policy_Folder}\gpt.ini from a domain controller and was not successful. Group Policy settings my not be applied until this event is resolved.
What is the cause of The processing of Group Policy failed error?
This issue may be transient and could be caused by one or more of the following:
The first thing you will want to do is take a look at the event viewer logs. In this instance it turned out to be a Journal Wrapping error which was causing File Replication Services to fail on our domain controllers.
The error was: The File Replication Service has detected that the replica set "DOMAIN SYSTEM VOLUME(SYSVOL SHARE)" is in JRNL_WRAP_ERROR
Microsoft's solution says to do the following in the registry:
Set the "Enable Journal Wrap Automatic Restore" registry parameter to 1
However if you are running on a post Windows Server 2000 than this is not a good solution. Instead you should use the Burflags method as described by Rune in this article: http://adfordummiez.com/?p=61
After that try running gpupdate /force and it should result in success!


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The plans PTel Mobile offers no-contract plans, unlimited plans and pay-as-you-go (PAYGO) plans. Each plan comes with different rates and data.
The no-contract plans offers unlimited talk and text with all the plans. The unlimited plans come with unlimited talk and text. The cheapest plan comes with 250 MB of data while all the others are unlimited. The best value plan comes with unlimited talk, text, data, MMS, and global text, as well as the first 2 GB of data at high-speed, 4G LTE max speed and $5 of international dialing credit. PAYGO rates go by minutes, texts, megabytes, MMS, and international SMS. The option to buy minutes and other credits in bulk is available.


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Decorative Concrete
Adara Apartment Pool
Architect: B+A Architecture
General Contractor: Morrow Construction
Concrete Contractor: Artistic Concrete Surfaces, LLC
RMX: Quicksilver Ready Mix Inc.
KU Memorial Drive Reconstruction
Owner: University of Kansas
Eng: Professional Engineering Consultants, PA
General Contractor: Kissick Construction Co.
RMX: Midwest Concrete Materials, Inc.
Gateway Interchange
Owner: Kansas Department of Transportation
Engineer: HNTB Corp, HDR Inc., GBA Architects and Eng.
Contractor: Gateway Interchange Constuctors
RMX: Fordyce Concrete
The Gateway Interchange was an Excellence in Concrete Award Winner!
Low Rise Buildings
I Fly
Owner: Skygroup Investments, LLC
Architect: Hodges Architecture
Engineer: Walter P. Moore
General Contractor: ARCO National Construction-KC, Inc.
Concrete Contractor: Lithko Contracting, Inc.
RMX: Geiger Ready Mix Co, Inc.
Repair and Restoration
Parking Facility C Rehabilitation
Owner: Unified Government of Wyandotte County
Engineer: H.W. Lockner, Inc.
Concrete Contractor: John Rohrer Contracting Company
RMX: Fordyce Concrete
High Rise Buildings
KU Hospital Cambridge North Tower
Owner: University of Kansas Hospital
Architect: Cannon Design
Engineer: The Structural Alliance
Concrete Contractor: George J. Shaw Construction
General Contractor: J.E. Dunn Construction Co.
RMX: Talon Concrete and Aggregates
Thanks to everyone who joined us at the Flint Hills Discovery Center in Manhattan, KS for the Awards Banquet Program!


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Actor-filmmaker George Clooney, also a first-time father-to-be, says that he is happier than before.
During an interview with eonline.com, he spoke about his wife Amal Clooney and their babies.
"Can you believe it?! Yeah, (I'm) even happier (than before)," he gushed.
"I didn't know that we'd have kids. I was very happy that we were going to get married and then (a pregnancy) seemed like the next step."
Asked if he's busy baby-proofing their home or practising how to change diapers, George said: "Hang on for a minute. I played a paediatrician on 'ER' (medical drama)."
George continued: "So I know how to work on extra children... If there's any accidents I'm there. I'm the guy."
They are yet to name their twins.
Explaining their reluctance to do so before meeting them, he teased: "Because I've had friends pick out names around their parents and then it becomes... whatever name you pick they're like, 'Oh, I don't like that. That guy's a prime minister... Can't name her Susan. You remember your Aunt Susan?'"
(With IANS Inputs)


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Ok, so this is the first item, I'm actually posting. I've lurked here for eons, but haven't had anything worth posting, or I've just simply been too lazy.
I also decided to post this because I searched quite a bit for nursing dresses (that might also be flattering), there wasn't much to be found. This summer after having my baby, I wanted something girlie and flattering to wear, which would also hide my baby pooch. When you're pregnant the belly is cute, but afterwards it's only cute in a flabby way and not everyone's into that.
Not only that, I wanted something that would cover my chest too. Anyhoo.... enough talk. Here's what I came up with.
I've since come up with a million ways to hide the booby pocket.
tata da
The booby opening looks lopsided here, but it isn't. I had my hubby take the pic and he was just shocked to see it.


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Coupons count as tips. You get coupons in the Sunday and Wednesday mail, if you don't. Then click here for Insert Insanity
Sign up for these sites, and get (1) FREE naughty picture with each site you sign up for! (more than 1 email may be used, if are approved)
My email is: email@example.com to make some of the processes easier :)
Shop-At-Home (gives you % back on online purchases-- better than Ebates)
Ebates (gives you % back on online purchases)
How to do it: (easy way)
- Go to page
- New member
- Use my email in the refferal thingy :)


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Troop F
Tpr. Angela R. Wood
Contact Information
55 Crystal Run Rd.
Middletown, NY 10941
Phone: (845) 344-5328
Counties in Patrol Area: Greene, Orange, Rockland, Sullivan, Ulster
Latest Troop News
Congratulations to all of the applicants who completed our 2013 Entrance Examination.
We encourage all applicants to continue checking our website, exam scores were recently released. It's very important to keep your information updated. You can click on the following link, update your contact information. Review the qualifications for the next phases of the process, which include physical ability, education, and tattoo policy.


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On Love and Tolerance — Moment of Truth #26
Love and Tolerance are misunderstood and misapplied in the secular mind. They are distorted versions of Virtues taught by the Catholic Church. Sometimes this effects us in the Church as well. Catholics can get disoriented and lost by messages that seem to coincide, when they are actually very much in conflict.
Tiny Crucifixions — Moment of Truth #25
Jesus Christ conquered sin, death, and evil through His crucifixion. Not by force of will, but by submitting Himself to the will of The Father. We must suffer "tiny crucifixions" in life in order to conquer the evils of the world
A Reflective Perspective — Moment Of Truth #24
We check mirrors all day to make sure we look "well ordered" on the outside. But we don't often look within ourselves to make sure we're well ordered on the inside. Catholics, and The Church need a reflective perspective, and look deep within ourselves and see what's out of order, and needs to be put right.
Critical Disservice — Moment of Truth #23
The ACLU is once again working its black magic in an attempt to force the Catholic Church to provide abortions to illegal immigrants. And in the Church we respond to that by reducing the truth to a constitutional debate. That's just not good enough!
In the Name of Love — Moment of Truth #22
We support vice, indifference, and pave new paths to disorder...all in the name of love. Disordered love.
The Good, The Bad, The Balanced — Moment of Truth #21
We have plenty of radicalized Catholics, plenty of modernized Catholics. But where are the balanced? Where are the Catholics who know how to BE Catholic?
Killing the Beautiful — Moment of Truth #20
The devil, and those tho give their wills over to him, tries very hard to take every beautiful thing away from you, by teaching you to kill it. Because The Beautiful compliments and preserves our own nature. By taking away The Beautiful, he can better undo YOU.
Seeking The Lord — Moment of Truth #19
Lots of people are seeking the Lord. But are they looking for him for the right reasons? Do they know how to look for him? Is Jesus just a companion, or master of our lives? Do we seek the "niceness" of Jesus, or the GOODNESS of Jesus?
Spiritual Masturbation — Moment of Truth #18
When the Catholic Homily is reduced to little more than a pep talk from the pulpit, the faith becomes little more than spiritual masturbation.
The Atheist Moral Code — Moment of Truth #17
Atheists say that they don't need to believe in "a god" or in a religion in order to be moral. But that's not true. An atheist can BEHAVE morally without believing in God, but they cannot BE moral without believing in God.


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- Details
- Specs
- Reviews
The CSHC64 combines a 4x6 telephone module and a 4 port Category 5e data module in a single black metal housing for voice and data distribution. Cooper Wiring Devices offers Combination Service Modules to provide space and cost savings for terminating voice/video or voice/data in its MediaSync Structured Wiring Enclosures. The modules are enclosed in black metal housings and combine voice and video modules or voice and data modules to provide multiple service outputs.
Features & Benefits:
- Fits easily into any MediaSync Structured Wiring Enclosure
- Provides 4x6 telephone module with RJ31X and expansion jack and 4-port Cat 5e data module
- Video splitters are bi-directional, supporting cable modems, digital cable and PPV systems
- RJ31X jack allows for connection to security panel for dial-out access on line 1when alarm is triggered
- Install 75-Ohm termination caps on unused outputs to reduce likelihood of signal distortion
- Use expansion jacks to connect one telephone module to the next to expand number of locations for voice application
Welcome to MediaSync, Cooper Wiring Devices' new line of home networking and control products. MediaSync is state-of-the art structured wiring technology that offers maximum connectivity, convenience and flexibility. More than just well-connected home solutions in a box, MediaSync brings you ways to manage multiple telephone lines, create a cost-effective home network, surround yourself with sound and music, experience home entertainment at its best and complete the system with a full line of communications outlets.
- Fits easily into any MediaSync Structured Wiring Enclosure
Specifications Manufacturer Cooper Wiring Devices Manufacturer Product No. CSHC64 UPC 032664654459 Connections RJ45 jacks and F-type connectors Outputs Six Construction Enclosed Metal Housing Color Black Standards Compliance cETLus, UL 1863 Listed Connector Type 4x6 telephone and 4 port Cat 5e Dimensions 3.14" H x 9.64" W x 2.39" D Manufacturer Warranty 10 Year Limited


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"Only when I experience something do I compose, and only when composing do I experience anything.".
Gustav Mahler
With the invaluable help of the archives department of the Musikverein in Vienna and the Mahler media library in Paris, we take a new look at Mahler as conductor and opera director. With a parallel study of his relationship with literature and nature, key sources for his work, the exhibition aims to put forward a more complete view of Mahler's life and his creative process.
CuratorsGuy Cogeval, director of the public establishment of the Musée d'Orsay and the Musée de l'Orangerie
Pierre Korzilius, director of the French Institute, Düsseldorf


text:
* Your list is public by default.
Alternative Titles
English: The Harvest Night
Synonyms: Shukaku
Japanese: 収穫の夜
Type: OVA
Episodes: 2
Status: Finished Airing
Aired: May 25, 2002 to Nov 25, 2002
Producers: Blue Eyes
Licensors: NuTech Digital, Adult Source Media
Studios: Triple X
Source: Original
Genres: Hentai
Duration: 30 min. per ep.
Rating: Rx - Hentai
Score: 6.091 (scored by 823 users)
1 indicates a weighted score. Please note that 'Not yet aired' titles are excluded.
Ranked: N/A2
2 based on the top anime page. Please note that 'Not yet aired' and 'R18+' titles are excluded.
Popularity: #7199
Members: 2,043
Favorites: 9


text:
3 great investment opportunities (Jakarta)
Here are 3 great investment opportunities. I am going to give a description of each and I'm also going to give a brief description why.
If you would like more information then please get in contact with me by phone/email or we can meet up for a coffee.
The main reason my wife and I are selling is so we can buy a 3 bedroom apartment in kuningan city.
Everything advertised here is owned by my wife and I.
74sqm 2 bedroom condo in Carita.
This condo is on the top floor and is 5meters away from the beach.
There is constantly water sports on the beach from jet skis, banana boats, and squid huts in the middle of the sea where you can go out and relax.
Also you can sit and relax on the clean beach and enjoy fresh crab/lobsters/prawns and fish that was caught the same morning.
The sea is very clean and blue especially during the months between March - September.
The view from the condo is not only sand and sea but also has a beautiful view of 3 very large volcanoes. The most popular is Krakatoa that you can go and visit just by walking down stairs from the condo, getting on a boat and going out into the sea for about 1hour and 30mins.
In Krakatoa there are clean/beautiful coral reefs where you can go snorkeling and see hundreds of beautiful tropical fish, and take a walk up the volcano. You won't reach the top as I have tried and failed miserably. These volcanoes are active and you can constantly see them erupt.
1000sqm plot of land about 5mins walk from the condo.
You can do what you want with this plot of land from growing teak wood to building another large villa/condo.
Now there are many reasons why this is such a good investment from Ratu Atut Shosiyah and her brother being sent to jail.
Also they are in the process of building an airport that is predicted to be finished within the next 2 years, all the roads are being renewed and they are now starting to build more complexes in the area. This is already a big tourist attraction but when the airport is complete the value will shoot through the roof.
There are many more reasons to why the price of this land and condo is increasing but I would prefer to go into more detail in person.
2 bedroom apartment in bassura city that is still in south Jakarta but is heading west.
This is 44sqm and on the 20th floor.
My wife and I have owned this apartment for less than 1 year and the price has already increased by 100,000,000 IDR
Bassura city is a very large project and will turn into a very large and popular complex. The value is constantly increasing.
Price for each.
Carita condo Protected content IDR negational price.
Carita land Protected content IDR NON negational. (Fixed price)
Bassura city Protected content IDR NON negational. (Fixed price) if you go to developer then they are asking for 530,000,000 IDR
You do not have to use any of these as an investment. You can enjoy the condo on the weekends and rent it out to other tourists, build a house on the land, or live in bassura. But each will constantly increase in value.
We are selling cheap as we want a quick sale.
We have made a lot of use from the condo going up for a weekend every month to relax, it's about a 3hour and 30min drive from Jakarta.
we have allowed the locals to grow fresh chillies and banana trees on our land, And bassura city has gone up in value around $10,000 in 9months.
My wife and I have a lot of business in central Jakarta but want to start buying in more prestigious complexes.
If you would like photos or more information then
Call Protected content
Email Protected content
Or we can arrange a meeting.


text:
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By: Ken Inchausti, Director, Reputation & Media Relations at Novo Nordisk US
It's hard to come up with a more personal topic than healthcare. We're living longer which means our chances of facing a serious disease are greater, and that gets us thinking about our doctors, the medicines we have to use (and pay for), and the lifestyle changes we have to make. With everything feeling so complicated, is it possible to have a simple conversation about what's working, what's not, and why? We think it is.
We've been working in diabetes for almost a century, bearing witness to some of the most important milestones in the history of this serious disease. We also know that there's a lot more to discuss, debate, and question when it comes to healthcare. We know you have a lot of questions. We do too. And we know that the answers aren't always clear. But one thing is: people living with diabetes and other chronic diseases shouldn't be limited by their conditions.
So let's talk about this… together. That's why we've created this blog called Perspectives. In it, we're going share our point of view and some of what we're seeing in American healthcare. Be a part of this community, but also make sure you check out our Community Guidelines when it comes to posting.
Perspectives is for US audiences only. If you are outside of the US, learn more about Novo Nordisk at www.novonordisk.com.


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Come home to Bromley House Apartments where community is everything. We offer extra-spacious Apartment Homes with upgraded kitchens and bathrooms. Amenities include a beautiful pool area, fitness center, Beauty Shop and more. We are a low-rise community with elevator service and are conveniently located close to public transportation, shopping and Center City Philadelphia. Call today to schedule your tour of Bromley House Apartments in East Oak Lane Philadelphia, PA.
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I will give Bromley House a good rating, because the apt complex is convenient to main streets and public tran Read Moresportation. I like that it has both lot and street parking. The noise can be managed a little better. The parking lot needs to be shoveled during the snow to avoid falls or cars becoming stuck.
January 15, 2014
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December 24, 2013
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November 26, 2013
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City Chairman Assem Allam has caused further disgruntlement amongst City supporters by releasing a club statement in the last hours.
Following on from his recent revelations that he will press ahead with a name change to Hull City Tigers in the New Year without undertaking any fan consultation, Assem Allam has now stated that he will refund the costs of season tickets to any supporters who wishes to claim a refund.
Supporters ground and campaigners City Till We Die have since urged supporters now to take up the offer made by Assem Allam and to continue to support the club and players, especially ahead of a crucial clash with Crystal Palace at the KC Stadium this Saturday.
The statement reads that supporters have until Friday 22 November (5pm) to claim a pro-rata refund on their season ticket with a similar opportunity operating between Monday 25 November (9am) and Friday 29 November (5pm.)
The club statement, which is published on the official website, goes on to state;
Dr. Assem Allam has made this offer in light of the confusion that followed the recent meeting with representatives of supporters` groups, and the fragmented messages that have emanated since that meeting. That meeting closed with one of the representatives requesting the opportunity to develop alternative commercial models, and nothing has yet been presented to the Club.
Dr. Allam feels a sense of duty to the majority of fans and stakeholders to secure the future stability of the Club, whilst continuously improving the quality of football, and as such is advancing his plans to generate the commercial opportunities necessary to forge a sustainable future. He is also keen that the majority of fans are able to focus on enjoying the quality of Premier League football at the KC Stadium, without being diverted onto minority interests."
Hull supporters will still be watching "Their club" long after the next ten owners are gone – never mind the next one!
The current owner's tactic? – You pays YOUR money – you make YOUR choice – over to you fans!!!


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LANSING — "And there's quite enough hope and quite enough power to chase away any gloom. For Jesus, Lord Jesus, is in this very room."
On a bitterly cold night, the harmony of men's voices fills the confines of a Lansing Correctional Facility gymnasium.
The East Hill Singers, a choir made up of minimum-custody inmates and community volunteers, sing Latin and Italian at a performance inside the prison. They receive emphatic applause and curious looks from other inmates.
Last year at this time, the fate of the well-known choir appeared in doubt. Budget cuts kept the inmates from traveling to perform at Kansas churches.
But after a one-year hiatus, the inmates will once again leave prison walls. The group performed Jan. 17 at Atonement Lutheran Church in Overland Park, a concert that was open to the public.
Last year the inmates appeared by video as community members performed, a desperate move to keep the choir in the public eye. The concerts were an essential funding source for Arts in Prison, the nonprofit group that organizes and privately funds the choir. Without donations from the concerts, Arts in Prison wondered how long it could continue the program.
"The point is kind of having the East Hill Singers there - all of them," said conductor Kirk Carson. Prison officials said they simply couldn't pay staff overtime to accompany the inmates last year.
But this year, Warden David McKune and Arts in Prison have come up with a new plan. Instead of paying employees overtime, he will use administrative staff who volunteer and a regularly scheduled employee to transport the inmates.
However, those employees alone aren't enough to supervise every aspect of the concert. The prison also will rely on 33 trained volunteers from Arts in Prison to oversee the 27 inmates. The volunteers, who have been trained by the Kansas Department of Corrections, oversee the choir during regular practices, and they have a proven track record, McKune said.
"They're fully trained and authorized to supervise that group of men," McKune said. "I'm comfortable with what we're doing or I wouldn't do it."
Prison officials have long commended the program because it fills inmate time with constructive and fulfilling work. The program teaches positive hobbies that will be essential if inmates are to avoid returning to prison. Also, released inmates are allowed to rejoin the choir as volunteers.
When the public concerts ended last year, many worried that inmate participation would drop. They wondered if the inmates were singing for the lure of a concert outside the walls and the home-cooked meals served by church members.
"It's the dangdest thing. I thought our membership would falter," Carson said.
Instead he recruited several new faces. Two dozen men also petitioned Carson to start a music theory class. Carson, a former university instructor, wondered if the men knew what they were asking. The class was so thorny for college freshmen that 30 percent of the students would drop it.
"That's how we knew who was serious," Carson said.
Students didn't have access to a piano or keyboard, so Carson made paper cutouts of a keyboard so his students could practice.
Seven of the original group are starting their second semester in the class.
"I lost 60 percent of them, but you know what - this is a prison. They didn't take French horn lessons when they were growing up," he said.
Most of the men in East Hill Singers had never been part of a middle or high school choir, or had private lessons.
The overall program is considered sacred to several inmates.
Joey Hernandez could be released as early as February. He said the class had allowed him to look at criticism and imperfection in a different light.
"You have to learn how to be a team player," he said. "You have to learn not to take constructive instruction personally."


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Hackers Attack 92,000 Korean Computers
Some 1,000 Korean Internet sites were attacked, leaving 92,000 Korean computers infected with a malicious computer program, the Korea Information Security Agency (KISA) announced Thursday.
The KISA said that it took emergency measures against a malicious computer program that steals the personal information of Korean gamers. The agency told 1,000 Internet sites that they had fallen victim to large-scale computer break-ins and advised them to delete the program. Digital Chosunilbo (English Edition) : Daily News in English About Korea
Back to: PC Security, privacy news


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Honoring Cuban-American Veterans
What follows is a revision of a piece I originally wrote in 2005 and re-posted at Babalu in 2007. It's my small way of honoring our veterans on this Veteran's Day 2009.
Veteran's Day has always held a special place in my heart. I'm far from being alone in feeling this way, but please allow me to feel a sense of personal pride on this day. The reason for this is that my father is a veteran of the Vietnam War.
As a youngster, I heard many of my father's Vietnam stories and his frighteningly detailed accounts of combat. The most harrowing account was of the day one of his platoon-mates set off a booby-trap, sending shrapnel flying through the air. My dad was fortunate and blessed to survive that day with relatively minor injuries. I heard about my dad's stay in an Army hospital and hearing the screams of other wounded soldiers writhing in pain. Some of those young men didn't survive the night. I also remember my father recounting our short time in Ft. Hood, Texas where he served the remainder of his time in the United States Army (I was barely a toddler when we lived in Ft. Hood, otherwise the tragedy of last week would have resonated that much more with me).
Our family was blessed to have met other Cuban-American veterans and their families during my dad's service in the U.S. Army. It undoubtedly made our stay in a place far away from Miami much more like home. My memories are also rich with all the stories my dad and his fellow Cuban-American veterans shared years later at picnics, birthdays and long weekends at the beach. Needless to say, I have always felt an immense sense of pride for these men. There is no higher honor than serving your country and being willing to make the ultimate sacrifice.
What makes my father and his group of veterans even more special is that they weren't born in the United States. They were born in Cuba and escaped the island prison in the same way that so many did back in the early years of "the revolution". They were teenagers and young adults in their 20s, their futures suspended because of exile. These folks eventually chose to serve their adopted country against a foe much like the one they and their families fled from just a few years before. While many Americans protested and even left the country, these foreign-born men embraced the opportunity to defend freedom.
As I mentioned above, there is no higher honor than serving your country. There is one exception, however: serving your adopted country.
In Miami, there are at least four organizations of Cuban-Americans who have served the United States of America in the Armed Forces. These are:
- Veterans of Foreign War Jose Marti Post 10212
- American Legion Capt. Felix Sosa-Camejo Post 346
- Vietnam Veterans of America Candido Molinet Chapter 620
- Cuban-American Veterans Organization
I'd like to bring special attention to the name Felix Sosa-Camejo. Here's some information on Capt. Sosa-Camejo courtesy of this statement read before the Senate Committee on Armed Services in 2006:
(Felix Sosa-Camejo) came here, to Miami, as a 20 year-old refugee from Castro's regime and enlisted in the Army in 1963. Serving for five years, Captain Sosa-Camejo earned 12 citations, including the Bronze Star, three Silver Stars and two Purple Hearts. On February 13, 1968, in the heat of the Tet Offensive on the streets of Hue, his platoon was pinned down by enemy fire and unable to reach a wounded comrade. With disregard for his safety, Captain Sosa-Camejo ran through the intense enemy fire and pulled the wounded man to safety. This action would earn Captain Sosa-Camejo his second Bronze Star and would cost him his life.
(Babalu's) Humberto Fontova wrote this about Capt. Sosa-Camejo back in 2006:
"On February 13, 1968, the lead platoon was hit by an enemy bunker complex manned by approximately forty North Vietnamese Regulars. Upon initial contact the point man was wounded and lay approximately 10 meters in front of the center bunker. The platoon was unable to move forward and extract the wounded man due to the heavy volume of fire being laid down from the enemy bunker complex."Captain Sosa-Camejo immediately moved into the firing line and directed the fire against the enemy bunker. With disregard for his safety, Captain Sosa-Camejo ran through the intense enemy fire and pulled the wounded point man to safety. After ensuring that the wounded man was receiving medical treatment, Captain Sosa-Camejo returned to the fire fight and again exposed himself to the intense enemy fire by single handedly assaulting the center bunker with grenades killing the two NVA soldiers manning the bunker. As he turned to assault the next bunker an NVA machine gun opened up and he was mortally wounded. Captain Sosa-Camejo's valorous action and devotion to duty are in keeping with the highest traditions of the military service and reflect great credit upon himself, his unit, and the United States Army."
Next time you hear someone complain about Cuban-Americans' alleged (and blatantly false) lack of devotion for their adopted country; next time you hear an immigrant complain about this country, you might want to share these stories with them.
The following link is a copy of a speech by former U.S. Representative Dante Fascell in commemoration of the VFW Jose Marti Post's 20th anniversary back in 1991. It serves as a good reminder of one of the many sacrifices made by Cuban-Americans. Please take the time to read it, it's well worth the time.
To all veterans of the U.S. Armed Forces, and especially to our Cuban-Americans vets, my deepest gratitude and respect for what you've done and for what you stand for.


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After weeks of working to meet holiday deadlines, I'm ready for a little break. The girls take me out on a hunt for fairy house treasures. We collect bits of this and that on our walk: acorns, pebbles, twigs, and leaves. We splash in mud puddles and run through a cornfield, surrounded by the familiar smell of the last fallen leaves. Although its only 45 degrees, 3yo Lily refuses a coat. And to my chagrin, she never does complain of the cold.
Emma, recently 5 and infinitely more practical, wears a coat and carries a large pink "purse" that she's filled with her essentials: pencils and a sketchbook. Once home, I bake banana bread while they transform their found treasures into a cozy new windowsill fairy cottage. And as Lily licks the bowl I finally realize what I've been missing.


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Sinclair Broadcasting Team is the media giant you have actually never ever become aware of. Cenk Uygur as well as Ana Kasparian, the hosts of The Young Turks, inform you how Sinclair is promoting conservative propaganda via their channels. Inform us exactly what you assume in the comment area listed below.
" They are called "must-runs," as well as they arrive on a daily basis at television terminals possessed by the Sinclair Broadcast Group– short video clip segments that are centrally created by the business. Station managers around the country are routed to work them into the program over a duration of 24 or 2 Days.
Given that November 2015, Sinclair has actually ordered its terminals to run an everyday sector from a "Terrorism Alert Desk" with updates on terrorism-related information worldwide. Throughout the election campaign in 2014, it sent a package that suggested in part that voters need to not support Hillary Clinton since the Democratic Celebration was historically pro-slavery. A lot more just recently, Sinclair asked stations to run a short section in which Scott Livingston, the company's vice head of state for news, accused the nationwide information media of publishing "fake newspaper article."
As Sinclair prepares to broaden its stable of neighborhood TELEVISION terminals with a proposed purchase of Tribune Media– which would certainly add 42 terminals to Sinclair's 173– campaigning for teams have revealed issue concerning the size and also reach the combined company would certainly have. Its stations would reach more than 70 percent of the nation's households, including much of the largest markets.
Critics of the deal likewise mention Sinclair's readiness to utilize its terminals to advance a mostly right-leaning program. That practice has actually mixed wariness amongst several of its reporters worried concerning invasive direction from headquarters."
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Young Turk (n), 1. Youthful modern or anarchical participant of an establishment, activity, or political event. 2. A young person that rebels versus authority or social assumptions.( American Heritage Thesaurus).


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Tax Relief: Advisory Committee
Advisory Committee Members
Resolution Appointing Six Members to Terms Beginning January 1, 2016
Resolution Appointing Seven Members to Terms Beginning January 1, 2018
Request for Nominations for the Tax Relief for Pollution Control Property Advisory Committee
The TCEQ will be accepting applications for a potential replacement for a member of the Tax Relief for Pollution Control Property Advisory Committee to serve the remainder of the term expiring December 31, 2021. This position is one that is reserved for an appraisal district representative. The application period opens on November 2, 2018.
To apply, complete the nomination form and submit it to the TCEQ by 5:00 p.m. on December 3, 2018. Applications postmarked after that date will only be considered if there are insufficient qualified applicants. You can apply to nominate yourself or someone else to the advisory committee, but the TCEQ asks that only interested persons be nominated.
Questions regarding the advisory committee application process can be directed by phone to Kelly MacKenzie of the Tax Relief Program at (512) 239-4989 or by email to firstname.lastname@example.com.
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No meetings are scheduled at this time.
Past Meetings
The TCEQ is committed to accessibility. If you would like to request a more accessible version of the meeting audio files, please contact the Tax Relief Program. E-mail: firstname.lastname@example.com or Phone: 512-239-4900.
Advisory Committee Annual Reports
- 2017 Annual Report
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- "Benefit at the Site"
- Part B list
- Comments on Proposed Rule 2009-050-17-EN
- Carbon Capture Utilization and Storage Recommendation
- 2016 Review of Tier I Table and Expedited Review List
Related Rules
More Questions? Contact the Tax Relief for Pollution Control Program!
For more information, please contact the Tax Relief for Pollution Control Property Program by:
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Tax Relief for Pollution-Control Property, MC 110
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A Louisiana-based oilfield service firm is rebuffing federal and congressional investigators' requests for information about last month's fatal fire at a Gulf of Mexico production platform.
The company, Grand Isle Shipyard, has not responded to a request from five lawmakers for a briefing on the Nov. 16 explosion that killed three workers and injured others. It also has rebuffed the Chemical Safety Board's subpoenas for permits, testing results, safety assessments and other documents, investigators said.
Lawmakers, including Democratic Reps. Ed Markey of Massachusetts and Henry Waxman of California, said they wanted the briefing "in order to better understand (the) company's role in the recent Black Elk rig explosion . . . and the extent to which (it) may involve work done by Grand Isle Shipyard workers."
The Galliano, La. company did not respond to requests for comment.
An array of investigators are still trying to determine what caused a fire to ignite on the platform 18 miles from the Louisiana coast. Although the production facility is owned and operated by Houston-based Black Elk Energy, none of that firm's employees were on the site when the fire erupted.
Black Elk CEO John Hoffman has said Grand Isle Shipyard workers were performing construction work at the platform at the time of the blaze.
A Black Elk executive briefed congressional staff on the incident last week. Separately, the company has submitted records to the Chemical Safety Board and has volunteered to brief investigators on safety improvements.
Black Elk also gave federal regulators its plan for launching an outside audit of the company's government-mandated safety and environmental system, two days before a Dec. 15 deadline imposed by the Bureau of Safety and Environmental Enforcement that regulates offshore energy development.
Agency officials confirmed Black Elk submitted its audit plan on Dec. 13. A separate improvement plan is due later.
Last month, the bureau warned Black Elk that without safety improvements it could be barred from working offshore, following the Nov. 16 fire and more than 300 documented regulatory violations over the past two years.
The bureau ordered the company not to launch operations at a handful of facilities where work had been halted because of safety violations until the agency approves of Black Elk's repairs. The bureau also demanded that Black Elk develop a "performance improvement plan" and, by Dec. 21, give the agency a detailed analysis of its violation history that identifies ways the company has changed procedures to prevent repeat problems.
The company has not been barred from continuing most ongoing work; as recently as Monday, the safety bureau approved a minor change to a permit allowing the company to continue drilling a sidetrack detouring around the original hole at one of its Gulf wells.
Black Elk did not respond to requests for comment.
Founded in 2007 by Hoffman, a former BP and Amoco executive, Black Elk holds interests in 854 wells connected to 155 platforms spanning the Gulf of Mexico. It is the main operator on 98 platforms, according to federal records.
In the wake of last months' accident, scrutiny has focused on the company's financial health and its aggressive acquisition strategy, which is focused on buying old facilities and reworking the offshore wells to eke more hydrocarbons from the ground.
Standard & Poor's reaffirmed its B- rating of Black Elk's debt in September, citing concerns about liquidity amid the company's $192 million in funded debt and its vulnerability from a "small reserve and production base" combined with an "acquisitive growth strategy."
Several executives have left the company, including chief well officer Carl Hammond, according to a Sept. 25 filing with the Securities and Exchange Commission. In November, before the platform fire, the company's chief financial officer, James Hagemeier, was terminated, according to a separate SEC filing.
At the same time, regulatory filings show the company was struggling to repay debt and trim operating expenses.
The company also had been seeking new investors.
Much of Black Elk's funding comes from a New York-based hedge fund, Platinum Partners, which earlier this year reached a settlement to recover $32 million after it claimed it was bilked by a Ponzi scheme. According to a November 2011 presentation to potential investors, Platinum Partner Value Arbitrage Fund was Black Elk's biggest shareholder, owning 71 percent.
In November, five days after the accident, Standard & Poor's warned investors about Black Elk's credit risk, saying it was "highly leveraged" and had "very limited liquidity and . . . little capacity to absorb unexpected expenses or incurred liabilities."


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|Rishi P. Singh1*, Mark Shusterman2, Darius Moshfeghi3, Tom Gardiner4 and Michael Gertner2
|1Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA
|2Oraya Therapeutics, Newark, CA, USA
|3Stanford University, Palo Alto, CA, USA
|4Queen's University, Belfast, UK
|Corresponding Author :
|Rishi P. Singh
9500 Euclid Ave., i-32, Cleveland
Tel: 216-445-9496
Fax: 216-445-2226
E-mail: [email protected]
|Received January 05, 2011; Accepted February 21, 2011; Published February 21, 2011
|Citation: Singh RP, Shusterman M, Moshfeghi D, Gardiner T, Gertner M (2011) Evaluation of Microcollimated Pars Plana External Beam Radiation in the Porcine Eye. J Clinic Experiment Ophthalmol 2:134. doi:10.4172/2155-9570.1000134
|Copyright: © 2011 Singh RP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
|Related article at
Pubmed Scholar Google
Visit for more related articles at Journal of Clinical & Experimental Ophthalmology
Purpose: To evaluate the clinical and histological side effects of a prototype stereotactic radiotherapy system delivering microcollimated external beam radiation through pars plana in porcine eyes.
Methods: Five Yucatan mini-swine (10 eyes) were randomized to five treatment groups. Eight eyes were dosed with X-ray radiation on Day 1, and two eyes served as untreated controls. Treated eyes received doses up to 60 Gy to the retina and up to 130 Gy to the sclera using single or overlapping beams. The treatment beams were highly collimated such that the diameter was approximately 2.5 mm on the sclera and 3 mm on the retinal surface. Fundus photography, fluorescein angiography (FA), and spectral domain optical coherence tomography (SD-OCT) were obtained on days 7, 30, 60, and 110. Images were examined by a masked grader and evaluated for abnormalities. Animals were sacrificed on day 111 and gross and histopathological analysis was conducted.
Results: Histological and gross changes to eye structures including conjunctiva and lens were minimal at all doses. Fundus, FA, and SD-OCT of the targeted region failed to disclose any abnormality in the control or 21 Gy treated animals. In the 42 and 60 Gy animals, hypopigmented spots were noted after treatment on clinical exam, and corresponding hyperfluorescent staining was seen in late frames. No evidence of choroidal hypoperfusion was seen. The histological specimens from the 60 Gy animals showed photoreceptor loss and displacement of cone nuclei.
Conclusion: Transcleral stereotactic radiation dosing in porcine eyes can be accomplished with no significant adverse events as doses less than 42 Gy.
|Radiation; External beam; Macula; Porcine eyes; Macular degeneration
|The past decade has brought about a dramatic upgrade in our management of neovascular age related macular degeneration (AMD). The advent of photodynamic and anti-VEGF therapies, in particular, has greatly increased the prognosis for preservation and improvement of vision in this disease population. [1,2] However, all these therapies have some drawbacks. Photodynamic therapy (PDT) reduces moderate visual loss only to a modest degree, and only a few patients experience improved vision. Furthermore, the recurrence rate is high, with over 90% of patients requiring re-treatment after 3 months. [3] Ranibizumab, the most efficacious treatment of neovascular AMD to date, still leaves room for improvement. For example, 30% of patients remain in the 0 to 3 lines of vision loss category, and the treatment requires multiple re-injections as suggested by the Prospective Optical Coherence Tomography Imaging Patients with Neovascular AMD Treated with Intra-Ocular Lucentis Study (PrONTO), with the mean of injections for the first year being 5.6. [4] Intravitreal injections also carry the risk of retinal tears, rhegmatogenous retinal detachment, vitreous hemorrhage, hypotony, endophthalmitis, pseudoendophthalmitis, and possibly thromboembolic events in populations at high risk. [5,6] Furthermore, the social and budgetary burdens of repeated visits, injection fees, and pharmaceutical costs are large, and given the expanding population of AMD patients, alternative therapies with less re-treatment would be highly desirable.
|Most chronic diseases are treated via multi-modality therapies because they typically have complex and multiple etiologies. Combining therapies so as to attack the disease from multiple pathways leads to synergies in outcome. In the case of neovascular AMD, one alternative to anti-VEGF therapy and photodynamic therapy is external beam radiation. The use of low dose ionizing radiation for control of neovascular growth is based on experimental and clinical evidence and has a sound scientific basis. Ionizing radiation possesses the ability to destroy vascular tissue, and low-dose radiation has been shown to inhibit new blood vessel growth. [7] Theoretically, precise radiation delivery to the macula can selectively inhibit proliferating endothelial cells with limited destruction of retinal tissue and no systemic side effects. Moreover, Takahasi and colleagues found that new capillaries or vessels are more sensitive than larger vessels or fibroblasts. [8] Vascular endothelial cells in particular are more radiosensitive than other mesenchymal cells types such as fibroblasts and smooth muscle cells. [9] As an additional benefit, ionizing radiation can inhibit the inflammatory response, which is thought by many to play a role in the formation of CNV in AMD.
|The rationale for radiotherapy in neovascular AMD is multifold. First, it would attenuate the acute and delayed inflammatory response and subsequent CNV reactivation. Second it would inhibit the rapid formation of fibroblasts after treatment, and thus lead to less scar formation (as it does in the treatment of dermal keloids). Finally, it would lead to the closure of rapidly dividing endothelial cells which are the main pathological component of the CNV. This has been most recently demonstrated by the use of epiretinal radiation (Epi-Rad90T Ophthalmic System), with results similar to anti-VEGF therapy alone. [10].
|This study utilized a prototype stereotactic radiotherapy system for the delivery of micro collimated external beam radiation. Three sequential beams were delivered transconjunctivally, through pars plana, converging upon the retina. The study evaluated radiation to the eye of Yucatan mini-swine in escalating doses. This study examined the technological proof of concept as well as the dose range for potential adverse events using clinical exam, gross and microscopic histology, fundus photography, fluorescein angiography (FA), and spectral domain optical coherence tomography (SD-OCT).
|Study design and treatment
|Yucatan mini-swine were chosen for this study due to their resemblance in structure, size, holangiotic vascular pattern, and nontapetal fundus with that of the human eye. [11] Institutional animal care and use committee (IACUC) approval was obtained prior to study commencement and the study adhered to the ARVO animal statement on the treatment of animals. The animals were obtained from S&S Farms (Ramona, CA). Upon arrival, animals were examined to ensure that they were healthy and quarantined for eight days before study enrollment.
|Ophthalmic examinations (slit lamp and indirect ophthalmoscopy), fundus photography, and fluorescein angiography (FA) were performed on each eye prior to treatment and at 7, 40, 75, and 110 days. Ophthalmic observations of both eyes were scored and recorded according to the McDonald Shadduck system (as described in Dermatoxicology, F.N. Marzulli and H.I. Maibach, 1977 "Eye Irritation", T.O. McDonald and J.A. Shadduck (pages 579-582). Intraocular pressure (IOP) was measured with a Tono-Pen XL (Medtronic ENT, Jacksonville, FL) on days 7, 42, 75, and 110. Spectral domain optical coherence tomography (OCT) was performed with a Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA) and with an RTVue FD-OCT (Optovue, Fremont, CA). Two OCT devices were used to determine whether imaging anesthetized pigs was feasible with both machines. Swine were weighed prior to each anesthesia procedure (radiation dosing or ocular photography), and were euthanized on Day 111 or 112. Globes were collected, fixed in 4% formalin, and submitted for histopathological evaluation.
|The radiotherapy was delivered in a single session via the Oraya Animal Test System (ATS). Five animals (10 eyes) were randomized to five treatment groups. Eight eyes were dosed with radiation on Day 0, and two eyes served as untreated controls. A collimated, single-beam device (including a low-energy orthovoltage X-ray source, scleral interface and automated robotic positioning system) was used to deliver X-ray energy to the retina of each dosed eye (Figure 1). The robotic positioning system allowed for the single beam to be projected to the retina from various angles. Radiation treatments were performed at 100 keV maximum beam energy in which the ratio of surface to target dose was approximately 2.5:1. The treatment beams were highly collimated such that the diameter at the sclera was 2.5 mm and 3 mm on the retinal surface. For six eyes, the radiation dose was delivered in three consecutive beams, through various scleral entry points calculated to place the beams onto a single retinal target. For two eyes, the radiation dose was delivered in one beam. Lateral canthotomies were performed on all eyes prior to dosing for access to the limbal space. Animal received between 0 Gy and 60 Gy and detailed treatment parameters and total radiation delivery are shown in (Table 1).
|There was no unscheduled mortality and all swine gained weight during the study. Slit lamp and gross ophthalmic examinations revealed conjunctival irritation (congestion, swelling, and/or discharge) on Day 7 in six of eight treated eyes; the irritation was generally mild and related to the canthotomies. There were no other significant external findings seen during the remainder of the study. Intra-ocular pressure (IOP) was measured on days 7, 42, 75, and 110 and varied throughout the study in all eyes. There was no significant difference noted in intraocular pressure within the same animal over the course of the study and amongst control and treated animals at all timepoints.
|Fundus photography, SD-OCT, and FA were performed prior to irradiation and after at days 7, 40, 75, and 110. Each article was examined by a masked grader (Ronald P. Danis, M.D., Professor of Ophthalmology and Visual Sciences, Univ. of Wisconsin) and evaluated for abnormalities. Fundus evaluation revealed no abnormalities of the targeted area except in the 42 and 60 Gy treated animals. At Day 7, a circular retinal lesion with apparent depigmentation was noted in the area targeted with 60 Gy (Figure 2). The lesion persisted on fundus exam until Day 110. Additionally, the 42 Gy single beam eye demonstrated a retinal lesion on day 110, visible as a greenish hue inferior to the optic nerve, and representing a change from pre-treatment fundus photographs. There were no retinal hemorrhages, cotton wool spots, or vascular occlusions/sheathing seen in any specimen. FA demonstrated staining in late frames of the angiogram in the 60 Gy animals, but no evidence of early hypoperfusion changes within the retinal circulation. Additionally, there was no delay within the choroidal fluorescence pattern to suggest ischemia or poor perfusion (Figure 3). The highresolution OCT of the targeted region failed to disclose any definite abnormality in the control and treated animals up to 42 Gy. In the 60 Gy animals, SDOCT demonstrated subtle retinal thinning with a transition zone. This was first seen at day 30 and didn't not change significantly to day 110 (Figure 4).
|Enucleated eyes were prepared for gross and histological analysis at days 111 & 112. Gross examination of the exterior aspects of the globes revealed no evidence of scleral ectasia, scarring or fibrosis, corneal opacity or episcleral tissue reactions. Of note, the sclera in the 60 Gy single-beam group received a dose of 129.5 Gy, without any apparent gross findings seen. Internal examination revealed unremarkable intraocular structures in all eyes, except Group A, the single-beam 60 Gy group. In this eye, in the posterior pole juxta-papillary region (akin to the human macula), a sharply demarcated, round tissue reaction was noted. This ~2.5 mm region appeared to be faintly hypopigmented (Figure 5A).
|Histological examination of the anterior segment by a masked pathologist was performed in the radiated regions. The histology of the cornea, limbus, and sclera was normal in all eyes, without signs of necrosis or inflammation. The ciliary body and pars plana regions were free of cellular infiltrates and edema. The sclera, choroid, retinal pigment epithelium (RPE), and neural retina were step-sectioned and examined at multiple levels. There were no abnormalities seen except in the 60 Gy single beam specimen. The gross finding in this eye shown in Figure 3, demonstrated a histological correlate, where photoreceptor loss was seen, with a clearly demarcated transition zone (Figure 5B and 5C). The inner retina was largely unaffected, with a continuous layer of ganglion cells showing a rich complement of Nissil staining (polyribosomes), indicative of health. The RPE layer was intact throughout the lesion, with the only pathology evidenced by some flattening of the RPE cells at the center (Figure 5D), which was not felt to be artifactual but representative of apoptosis induced by radiation.
|Stereotactic radiation dosing of 8 swine retinas with 21, 42, or 60 Gray delivered in 1 or 3 beams was accomplished successfully using the prototype system. There were angiographic, gross, and histological retinal changes seen at the highest tested radiation doses associated with photoreceptor loss and preservation of the inner retinal layers.
|Previous randomized clinical studies have evaluated radiation for the treatment of age related macular degeneration. [12-15] The Radiation Therapy for Age-Related Macular Degeneration (RAD) study was a multicenter, randomized double-masked trial of 205 patients with subfoveal CNV (classic or occult lesions less than 6 MPS disc areas). Patients were randomized to either 8 fractions of 2 Gy external beam radiation, or to control sham therapy. At 1 year, no significant benefit to radiation therapy was noted as moderate vision loss (>3 lines) occurred in 51.1% of the treatment group and 52.6% of the control group. Other studies utilizing external beam exhibited similar results.
|Why have these trials failed to show significant efficacy outcomes? Marcus and colleagues hypothesized that the dose of radiation delivered to the macula was limited by technical inability to precisely localize energy on target. External beam radiation utilize linear accelerators which project a wide beam across ipsilateral and contralateral critical structures. [12] Due to this of imprecision, only a small amount of radiation was applied at each setting. Furthermore, no data supports the assertion that radiation fractions are indeed cumulative in biologic effect on choroidal neovascularization. Also, the patients' eyes were not mapped in space relative to the X-ray beam, and were not immobilized throughout treatment. Thus, confirmation and stability of beam targeting during the therapeutic fraction were not achieved, and fixed-beam high-energy devices directed radiation across critical structures, such as the lens, the ciliary bodies, and the optic nerve. The Oraya ATS system is highly precise in delivery because of the X-ray beam collimation, size, and delivery through the pars plana avoiding significant ocular structures.
|The study performed failed to show significant abnormalities associated with excess radiation to the targeted tissues except in the 42 and 60 Gy test group. The threshold for radiation in Yucatan mini-swine are not well documented and appears to be between 42 Gy and 60 Gy based on our results. Radiation has been known to cause an occlusive microangiopathy secondary to endothelial cell loss and capillary closure occurring after ionizing radiation treatment. Photoreceptors are more resistant to radiation, and animal studies have shown damage to rods with 20 Gy and to cones with 100 Gy. Although damage to photoreceptors has been seen, the inner retinal layers and retinal vascular cells are most affected, causing vessel closure and ischemic retinopathy similar to that in diabetic retinopathy. [16] This description correlates well with the 60 Gy hypopigmented lesions which stained in late frames and manifested photoreceptor displacement/loss and RPE flattening. The failure of the SDOCT to show significant change in the treated animals in lower doses than 60 Gy may be due to insensitivity of the device in detecting photoreceptor loss or RPE flattening and should be re-evaluated in future studies with longer time points. In addition, the choice of a different SDOCT that utilizes image averaging (Heidelberg SDOCT) would substantially improve the evaluation of the inner/outer segments.
|Interestingly no gross or histological findings were seen in the anterior segment of the animals treated. Radiation has been used for a variety of anterior segment indications such as ptergia. In the study by Beyer and colleagues, 30 Gy of Strontium 90 beta irridiation decreased ptergia recurrence and was not associated with significant ocular side effects. [17] However, in the cases of external beam radiation for conjunctival melanoma, doses up to 45 Gy have been associated with lash loss, limbal stem cell deficiency, and cataract formation. [18] The Oraya ATS system delivered 129.5 Gy in the highest dose category to the sclera without significant gross or histological damage seen. While the tissue may have slow cell turnover time which may account for the radioresistant properties of the anterior segment, the small size of the beams at the scleral surface (2.5 mm) my account for the lack of side effects seen. Even with the multibeamed animals, no significant adverse events were seen despite the close proximity of each treatment beam.
|At face value, the dose of radiation administered in one session between 42 and 60 Gy appears to be relatively safe in this short follow up. The question remains what the toxicity or safety would be in a much longer follow up or whether a change in the beam angles of entry will reduce the potential for delivery of radiation to non-macular structures. [19] Additionally, it is unclear what effect this dose of radiation will have in the compromised macular environment of macular degeneration since the biology of such entity could prove to be different. Finally, evaluation of RPE apoptosis would be useful as an additional safety measurement. These will be addressed in future studies with the actual clinical device and by using an artificially induced animal model of macular degeneration.
|In summary, transcleral stereotactic radiation dosing to the miniswine can be achieved with no significant adverse events seen at doses less than 42 Gy. Further studies are being conducted with the clinical grade device to verify safety and precise targeting in the mini-swine model.
|Figure 1
|Figure 2
|Figure 3
|Figure 4
|Figure 5a
|Figure 5b
|Figure 5c
|Figure 5d


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Did Jennifer Tilly Have Plastic Surgery?
November 3, 2008 in Asian Plastic Surgery,Celebrity Plastic Surgery by ericharatz | 7 Comments
When actress Jennifer Tilly turned 50 this year, fans were floored. The poker player looks just as good as she did when she began her rise to fame, nearly 20 years ago. Usually, when actresses her age look that good, they also look as if they are made of plastic, but Jennifer has a very natural appearance. Make Me Heal investigates whether or not Jennifer has good genes or a good plastic surgeon.
Jennifer's most famous attributes are her large, yet firm breasts. Never a "skinny mini," Jennifer's breasts are generally presumed to be real, yet fabulous. But her breasts have grown even larger and perkier in recent years, leading Make Me Heal to believe that Jennifer has an augmentation in the past few years.
Plastic surgeon Dr. John Di Saia agrees with Make Me Heal's assumption, saying, "Jennifer Tilly may have had implants and/or a lift. She looks pretty full in her later images."
Plastic surgeon Dr. Jennifer Walden also concurs, telling Make Me Heal, "She looks as if she has had a breast augmentation in the past given the fact that her breasts seem more voluminous in recent photos."
Just as remarkable as her bosom, is Jennifer's skin. Nary a wrinkle in sight, Jennifer's skin is in better shape than many women half her age, just beginning to use dermal injectable Botox.
Dr. Walden reveals to Make Me Heal, "She apparently has great genes (or a great plastic surgeon) since her face appears to look much more naturally youthful than the majority of women who are aged 50. She probably takes very good care of her skin without smoking or overexposure to the sun. If anything, her forehead looks so smooth that she may have had some Botox injections, but I think most of her look is attributable to very graceful aging."
Jennifer has sometimes joked that she owes her remarkable looks to plastic surgery, which may be true. Her face shows very little sagging in the neck region, which is how you can often tell a person's real age, even if their face is filled with dermal fillers. Her eyes also don't lack elasticity, but they aren't pulled looking either, both of which could be indicators of a well-done necklift and blepharoplasty.
Plastic surgeon Dr. Sherrell J. Aston tells Make Me Heal, "Jennifer Tilly looks great. However a very recent picture looks as if her quite heavy upper eyelids are less heavy and her neck and jawline looks tighter. Maybe it was just a great picture but I think there has been some work to help out."
He goes on to remind readers, "There is nothing wrong with a little cosmetic surgery. It is not morally wrong, unethical, nor illegal."
Indeed, if the results of plastic surgery were as good as Jennifer Tilly's, many more women would clamor for plastic surgery. Make Me Heal looks forward to seeing more of Jennifer's outstanding appearance on the big screen.
Read the complete plastic surgery profile of Jennifer Tilly on Plasticopedia, the largest online celebrity plastic surgery encyclopedia.
See Straterra online buying Before & After Breast Augmentation Photos
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7 Comments so far
Thoughts on
January 1, 2009 2:07 am
She's half Asian and Asians are known to age remarkably well. She probably has not had any sort of anti-aging plastic surgery like Botox or other injections. I know an Asian woman who is 54 yrs old and does not have a single wrinkle on her face (only faint crow's feet) and whose skin glows more than a 25 yr old's!
courtney on
March 17, 2009 8:01 am
her name is now jennifer titty
Michael Smeltser on
July 29, 2009 12:45 am
I was just watching one of her older movies (He's My Girl) and I saw how small her breast looked and that just made me so curious because in Bride of Chucky they are huge. Either way she is beautiful and one of my favorite actors.
Virna on
August 22, 2009 7:45 pm
I love Jennifer Tilly She's My Favorite actress ever i liked all her movies especially bride of chucky and seed of chucky:]
Virna on
August 22, 2009 7:46 pm
I really want to meet Jennifer Tilly one day
Christy on
February 23, 2010 9:53 pm
I would love to know what moisturizer she uses!!!-I'm 24 and already starting to get deep "laugh lines" and I don't smoke, stay out of the sun, and slather cetaphil cream on my face at least twice a day! lol
Verity on
April 25, 2018 4:21 pm
I know some far east Asians grow gracefully and some do not. They are human like the rest of the human race. Jennifer Tilly was smaller in size and chest in the late 80′s and did have breast augmentation in 1995. She does smoke and drink alcohol because I saw her for years doing so. I saw her at the cult of Chucky premiere in frightfest London in August 2017 and she had aged rapidly, wider and bulkier because she is approaching 60 years old. I can understand why she had plastic surgery and Botox before but you can't fight ageing I'm afraid. Sorry!


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JUMPS: to images on this page
Images of Real Cars
Hauler Images
Michael Waltrip ran the car at Talladega with sponsorship from Aaron's
Taken at Talladega in October by M.J. Scanlon Photography.(11-5-2010)
Terry Cook attempted and failed to make the race
Taken at Martinsville in October by Mark Agee.(10-27-2010)
Mike Bliss's first race with Prism Motorsports
Taken at Atlanta in September by Bill Blose of Photosbybill.com.(9-4-2010)
Ran at Talladega in April and will again in October with Michael Waltrip driving.
Image from a Michael Waltrip Racing PR.(9-2-2010)
Taken at Watkins Glen by Larry Scavnicky of Front Stretch Photos.(8-12-2010)
The scheme Michael Waltrip will drive at Infineon Raceway, the winner of the Toyota Sponsafier Contest.
Thanks to Brock Beard at Lastcar.(6-17-2010)
Taken at Michigan in June by Larry Scavnicky of Front Stretch Photos.(6-13-2010)
A one race deal for Waltrip to run at Talladega. McDowell and Blaney normally drive this car or the #66 car.
Taken at Talladega in April by Nancy who runs Jayski's Camping World Truck Series site.(4-24-2010)
Taken during Daytona 500 practice in February by Larry Scavnicky of Front Stretch Photos.(2-11-2010)
A one race deal for Michael Waltrip to run the #55 car at Talladega in April with Aaron's as the sponsor.
Thanks to MWR for the image.(3-10-2010)
for news and links, see the #55 Team News and Links page
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Main NASCAR Paint Scheme Gallery and Chart
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the Jayski site is owned and served by:
Paint Scheme Gallery Born On Date: Thursday, November 21, 1996
please do not to link the images directly [hot link] but save them to your PC/server
but can't stop everyone or worry about folks who steal stuff on the internet and message boards
would apprecaite it that if you wish to use them, copy them to your PC/server and give due credit
Some of these images were 'borrowed' from many other web pages,
or emailed directly to me, thanks.
I give credit to the site where the image is from, not the person who sends it in
folks who send in personal images of schemes will get credit
do not post images with a fan posed in them
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Licence application to hold a specified animal pathogen in England
Form to apply for a licence to handle the pathogen(s) under the provisions of the Specified Animal Pathogens Order 2008.
This publication was withdrawn on
This form is out of date and has been archived. Guidance on applying for a SAPO licence is available on the Health and Safety Executive website.
The Specified Animal Pathogens Order 2008 (as amended) ("the Order") prohibits any person from having in their possession any Specified Animal Pathogen listed in Part I of the Schedule to the Order or any carrier in which he/she knows such a pathogen is present, and from introducing into any animal any pathogen listed in the Schedule, except under the authority of a licence issued by the appropriate Minister.
The Order also requires that if any person has in their possession anything in which he/she has reasonable grounds for believing that a Specified Pathogen listed in Part 1 of the Schedule may be present, and does not hold a licence to handle that pathogen, they must notify a veterinary inspector immediately.
The purpose of the Order is to prevent the introduction and spread into Great Britain of Specified Animal Pathogens which are not endemic and which, if introduced, would cause serious disease and economic loss to the livestock industry. The Order has no application to any animal pathogen or carrier contained in licensed veterinary or human medicines.
Specified Animal Pathogen means an animal pathogen listed in Section II of this form and includes:
- intact pathogens
- pathogens which have been attenuated or genetically modified by any means
- any nucleic acid derived from an animal pathogen listed in the Schedule to the Order which could produce that pathogen when introduced into a biological system in which the nucleic acid is capable of replicating
Pathogens requiring a licence for possession or introduction into an animal are listed in Section II of this form.
For further information, see the guidance document on the controls on animal pathogens.