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Limb-Girdle Muscular Dystrophy (LGMD)
There are at least 19 forms of LGMD, and they're classified by the genetic flaws that appear to cause them. Some 15 specific genes that lead to production of muscle proteins have been implicated as definite causes of LGMD when they're flawed. MDA research was behind much of the work that identified these LGMD genes.
Genes, located on chromosomes in each cell in the body, are the codes, or recipes, for production of the body's various proteins. The genes associated with LGMD normally make proteins necessary for muscle function.
When protein problems arise because one of these genes is faulty, fibers in the muscles don't work properly. Gradually, the muscles become weak enough that people experience the symptoms of limb-girdle muscular dystrophy. Because LGMD is progressive, the muscles continue to get weaker throughout the person's lifetime.
Six of the genes that, when flawed, cause LGMD lead to production of proteins that are normally located in the muscle cell membrane, a thin sheath that surrounds each muscle cell, helping to protect it from injury during muscle contraction. If any of these proteins is missing, the membrane probably loses some of its "shock absorber" qualities and has a harder time protecting the muscle cell from injury during normal contraction and relaxation cycles.
In LGMD, the muscle membrane also may be "leaky," letting substances in or out that are supposed to stay on one side of the membrane or the other. Membrane proteins, when they're made correctly and are in their normal positions, may also perform other essential functions in the cell; these functions may be defective when one or more of the proteins are absent.
Not all of the muscle proteins associated with LGMD are in the membrane, however. For instance, calpain-3 is probably located in the main part of the muscle cell, and myotilin and telethonin are located in the part of the muscle cell that allows it to contract and relax.
The types of LGMD are generally classified by letters and numbers that indicate which gene is known or suspected to be involved and whether the disorder is inherited as a dominant or recessive condition, meaning whether one or two flawed genes are needed to cause it.
Some physicians classify LGMD according to which protein is missing or deficient, if this is known. For example, one form may be called alpha-sarcoglycan deficiency, and another is known as beta-sarcoglycan deficiency. In the future, the term limb-girdle muscular dystrophy may become obsolete and be replaced by more specific terms.
How is LGMD inherited?
Bewildered patients often ask, "But it doesn't run in the family, so how could it be genetic?"
LGMD can run in a family, even if only one person in the biological family has it. This is because of the ways in which genetic diseases are inherited.
LGMD can be inherited in one of two basic ways, known as the autosomal dominant pattern and the autosomal recessive pattern. The word autosomal means that the genes involved aren't on the X or Y chromosome and, therefore, don't have a preference for either men or women.
In diseases with dominant inheritance patterns, a person who inherits a flawed gene from one parent will have disease symptoms. That parent would also have the disease. In diseases with recessive inheritance, a person must inherit two flawed genes — one from each parent — to have disease symptoms. The parents don't have symptoms.
A recessive form of LGMD can show up in one person when there's no family history. Other family members may have been carriers, having no disease symptoms. Carriers have the genetic flaw (mutation) on a chromosome and can have a child with the disease, but only if the child's other parent is also a carrier. So it isn't unusual for carriers of a rare recessive disease not to know they're carriers until someone in the family develops the disease.
Just to make things a little more complicated, a person with LGMD may have a brand new genetic mutation (after all, they have to start somewhere), so there may really be no family history or even carriers of the disorder in the family. However, once someone develops a genetic disease, even if the mutation is spontaneous (new) with that person, he or she can then pass on the mutation to any offspring, thereby introducing the gene for the disease into the family.
The details of inheritance risks for any particular form of LGMD depend on many circumstances, including exactly which type of LGMD has been diagnosed. A good way to find out more is to talk to your MDA clinic physician or ask to see the genetic counselor at the MDA clinic. More information can be found in MDA's booklet Facts About Genetics and Neuromuscular Diseases.
To learn more, read In Focus: Limb-Girdle Muscular Dystrophy (October 2013 special report).


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Trading Statistics:
Realogy Holdings Corp. (NYSE:RLGY) closed its previous trading session at $12.64 with the gain of 5.42%. The company's market cap is $1.4 Billion, and the average volume is 2.45 Million. The Price to Sales (P/S) ratio of the stock is 0.23, while P/B (Price to Book) stands at 0.6. When we look at the Volatility of the company, Week Volatility is at 2.70% whereas Month Volatility is at 3.65%.
Earnings Forecast:
An earnings forecast is an analyst's outlook for a company's future quarterly or annual earnings. Future earnings predictions are perhaps the most essential input when trying to value a company.
7 analysts on average are expecting Realogy Holdings Corp. to report earnings of $0.9 per share for the current quarter. The Lower end of the earnings estimate is $0.75, while the higher end of the earnings estimate is $1. Comparatively, RLGY posted earnings of $0.99 per share in the same quarter, a year earlier.
Revenue Forecast:
Analysts' ultimate objective when projecting revenue is to determine the appropriate value for a stock.
6 analysts on average are expecting the company to report revenue of $1.75 Billion for the current quarter. The Higher end of the revenue forecast is $1.81 Billion, while the Lower end of the forecast is $1.66 Billion. RLGY generated revenue of $1.84 Billion in the same quarter, one year ago.
Price Target Estimates:
Price targets show what analysts believes a stock will be worth at the end of a certain time period. Price Target plays a critical role when it comes to the analysis of a Stock.
Analysts on average have given a price target of $14.61 to Realogy Holdings Corp. (NYSE:RLGY) stock.
(According to data compiled by finviz)
Simple Moving Average Analysis:
Moving average is significant analytical tool used to discover current price trends and the possibility for a change in an established trend. Simple moving average analysis helps investors to quickly identify if a security is in an uptrend or downtrend.
According to Finviz reported data, The SMA20 of the stock is at 7.47 percent, SMA50 is -11.8 percent, while SMA200 is -31.32 percent.
Return on Assets (ROA) Analysis:
ROA ratio indicates how profitable a company is relative to its total assets. The return on assets ratio shows how well management is employing the company's total assets to make a profit. The bigger the return, the more efficient management is in utilizing its asset base. The ROA ratio is calculated by comparing net income to average total assets, and is expressed as a percentage.
Realogy Holdings Corp. (NYSE:RLGY) currently has a Return on Assets (ROA) value of 1.9 Percent.
Return on Investment (ROI) Analysis:
Return on Investment measures the amount of return on an investment relative to the investment's cost. The Return on Investment (ROI) ratio of Realogy Holdings Corp. (NYSE:RLGY) is 5.5 percent.
Return on Equity (ROE) Analysis:
ROE ratio is a measure of profitability which calculates how much dollars of profit a firm makes with every dollar of stakeholder's equity. An increasing ROE indicates that a company is improving its ability to make profit without requiring as much capital.
Usually, the ROE ratio's between 12-15 percent are considered desirable. The Return on Equity ratio of Realogy Holdings Corp. (NYSE:RLGY) is 5.7 percent, according to data compiled by Finviz
Analysts Ratings:
A stock rating usually tells investors how well a stock's market value relates to what analysts think is a fair value for the stock, based on an independent evaluation of the company.
According to the Recommendation Trends of the stock polled by Finviz, the company has a consensus recommendation of 3.2 out of the scale from 1 to 5 where 1 stands for Buy and 5 means Sell.
Analyst Recommendation And Revisions:
Realogy Holdings Corp. was covered by a number of analysts recently, 1 rated the stock as Buy, 4 rated Hold, 1 rated sell and 2 gave an Underperform.
Stock Price Analysis:
The purpose of a stock price analysis is to study the behaviour of stock prices. It helps investors in determining whether buying, selling or holding on to a stock would be beneficial for them.
Realogy Holdings Corp. (NYSE:RLGY) stock price fell -56 percent over the past one year, while decreased -39.23 percent during the past 6 months. The stock plummeted -2.36 percent over the past month and fell -18.32 percent year-to-date. The stock's quarterly performance represents pessimistic momentum of -29.96 percent.

subset: commoncrawl


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No joke: NYC church is on George Carlin Way
NEW YORK (AP) — A bureaucratic error has put a Catholic church on a New York City street named after comedian George Carlin.
Carlin skewered the church in his act and gained fame with his foul-mouthed "seven dirty words" routine.
After he died in 2008, fellow comedians proposed naming the stretch of 121st Street where he grew up George Carlin Way.
The New York Times reports (http://nyti.ms/1w5haJI ) that priests at Corpus Christi Church objected because Carlin used to mock the church and crack jokes about the parish priests.
Under a compromise, one block was to be named after Carlin — not the block where the church is.
George Carlin Way became official Wednesday. Due to a clerical error it's two blocks long and includes the church.
City officials say the mistake will be corrected.
Information from: The New York Times, http://www.nytimes.com
Sorry we are not currently accepting comments on this article.


text:
Whether you have something good to say, or something bad, post your feedback here to better help other AZ'ers.
© 2001-2019 Audizine, Audizine.com, and Driverzines.com
Audizine is an independently owned and operated automotive enthusiast community and news website.
Audi and the Audi logo(s) are copyright/trademark Audi AG. Audizine is not endorsed by or affiliated with Audi AG.


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Buzzfeed finds the news people want to share by keeping its fingers on the social media pulse.
One of the key places its journalists find news is on Tumblr, UK news editor Richard James told students at Brighton Journalist Works
"Tumblr interesting because there is so much stuff," he said.
"It has quite a young demographic but it is miles ahead of everyone, breaking news and stories."
Buzzfeed has a young audience because it is writing about what interests them in an informative and shareable way.
As Richard pointed out, traditional media does not know how to deal with or categorise social media stars.
He said: "The Sam Pepper saga was a story the mainstream press would not know what to deal with.
"He's a YouTube star, so knowing what was being discussed meant we could reach out to people.
"There is huge gap in the market for someone like us as the mainstream press don't appreciate the fame of these people."
Buzzfeed also informs with what Richard described as explainer pieces to give people an introduction and wider understand of a story.
These often end up trending on Facebook or Twitter as they share well.
Richard said: "We want to be one stop shop for people wanting to find out more about Hong Kong protests.
"We try to do something different rather than blocks of text for example using an image of a poppy for every soldier killed in the First World War or Following Russian soldiers on Instagram in Ukraine. You can tell a story in a thousand different ways."
The amount of stories Buzzfeed is covering is growing and reporters are recruited every as the site is building a good reputation for news.
Richard said: "Our reporters are on the ground around the world from Liberia, Syria and Ukraine, this not what people assume Buzzfeed is doing.
"We are getting great exclusives and hard hitting pieces.
"It is a case of looking at what people are talking about, but not in the mainstream press, we see what people are talking about on Facebook.
"Reporters are spending the time properly investigating stuff.
"There is so much noise on social media I am pleased and proud at how we look at what is trending and then give you the full back story as sometimes online the wider context gets lost."
His advice to Journalist Works students is to be all over social media, watching and monitoring the trending subjects.
It is the best way to find news and the buzz of what is going on in the world.


text: Dating all the way back to the 1860s, American, leather goods brand Fyre boasts a long-standing association with producing excellent footwear that stands the test of time. Originally, the producers of hardy shoe wares for hardworking men, Frye today offers the same quality and durability it did way back when, but now with a focus upon fashion and a finger firmly on the pulse. Whether your pursuit is rugged or elegant, let Frye boots suitably punctuate your look with timeless pieces crafted in luxe leather and finished with tough-like details.


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The Pinnacles Poem
This poem really captures the feeling of walking in the rain!
1 / 5
Ascending The Pinnacles - in the Eye of the Storm!
Boots crunching, sticks prodding
Rivers roaring, bridges swinging
Fern fronds dripping, fantails peeping
Stone steps heaving, lungs gasping
School kids moaning, teacher pleading
Mist enveloping, felled kauri weeping
Pinnacles hiding, some despairing
Now descending, rain persisting
Water cascading, rock path slipping
Noses dripping, glasses misting
Tom tits fleeting, water rising
Dampness seeping, trousers clinging
Feet now squelching, Brad encouraging
Van appearing, walkers cheering
Kauaeranga Valley conquered!
Anne Manchester, March 21, 2012
Anne joined a Walking Legends group for a 4-day Coromandel Explorer Walk, which included this memorable climb to The Pinnacles. For info on this walk, plus other incredible NZ hiking tours, see: http://www.walkinglegends.com/walks/coromandel-explorer/
Thanks for sharing with us Anne!
Artículo de
4 day Coromandel Walking Tour
Join a small group and experienced guide to explore the dramatic Coromandel on foot! Jagged mountain peaks, stunning coastal views, waterfalls, abandoned gold mines and glistening white sand beaches make this a uniquely "kiwi" walking holiday.


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Reviewed by Jahod F (age 7)
My favorite animal was the Shih Tzu. It's cool. Its name means lion. I learned that Jack Terrier lives for 15 years or more. That's cool too.
If you like animals, you should read this book.
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text:
Electric Daisy Carnival, Las Vegas Motor Speedway | June 8, 2012 | 9:04 p.m.
Electric Daisy Carnival isn't really my scene. My personal soundtrack varies considerably more than 130-150 BPM. And with my kids' schedule necessitating a daily 6 a.m. wake up, I didn't know if I had an all-nighter in me. Fortunately, I really enjoy my job precisely because it puts me in situations I normally wouldn't put myself in.
It didn't start off well. Upon arrival at the Las Vegas Motor Speedway, I was sent from the tunnel to Gate A, back to the tunnel and back to Gate A because of confusion about where media was supposed to enter. Now, hot, sweaty and seemingly in a flashback to a frat party from 20 years ago, I really wasn't looking forward to the next 11 hours. Especially since I left my earplugs in my car. But then the people started arriving. The music (is it music or merely rhythm and melody?) started playing. The kids started dancing. My cynicism began melting away.
It was a long night of pretty lights and happy people. Seriously happy people. And there was something infectious about watching 100,000 people dancing and losing themselves in a sonic electronic maelstrom. How often do you get that many people together and not have one fight? I'm already looking forward to next year, and I might even shoot more than one night. Hopefully, I'll remember my earplugs.


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text:
Harnessing the global reach of the internet and the power of business process automation, Dotcom web sites work even while you sleep to bring you access to new markets and increased levels of profitability.
02 January 2013
This release will add enhancements to the Licence Master Client API that allow integrated applications to detect (and optionally tolerate) service outages and other conditions that prevent communication with the licence server.
25 March 2012
Licence Master 2.1 includes many new features, including:
Used with Store Adaptor 2.1, it is capable of selling licence upgrades and renewal from the DNN Store.
DotNetNuke anti-piracy module for web application developers and vendors.
Automate your licensing process for DNN module sales at DotNetNuke Store.
Full-featured online shop and simple Content Management System.
e-commerce applications and online stores using eTrader pro
Bespoke software development in ASP.NET and SQL Server.
Full-featured, impressive websites at an affordable price.


text:
Yale Has Won Cup In 13 Of Last 15 Years
BOSTON – Yale's varsity eight got back on track with an impressive victory over Radcliffe on the Charles River. The Bulldogs edged the Crimson by a little over a second to retain the Case Cup. Northeastern finished third.
The race, though, wasn't without a bit of controversy. The two crews clashed oars for two strokes at about the 800-meter mark, and Radcliffe protested the result.
"The race official was very clear with her call saying both coxswains were to blame for the clash and that it did not affect the outcome of the race," said Yale head coach Will Porter. "It was an unfortunate blemish on an otherwise great race."
The Bulldogs have now won the Case Cup in 13 of the last 15 years.
Yale finished with a time of 6:20.3, while Radcliffe came in at 6:21.9.
"Coming off the Princeton race [a loss], we had a tough week of wind and turmoil on the water but we were able to find another gear," Porter said. "The varsity eight really stepped up and nearly put together a complete piece."
Radcliffe did win the other four races. The closest finish was in the varsity four, where Radcliffe had a three-second margin of victory.
Radcliffe won the second varsity eight by nearly six seconds.
"We raced hard in all boats," Porter said. "We need to continue to work on our team speed in all boats. This team has a great spirit and is coming on. The youngsters have to be quick about processing races, learn and move forward. We need to improve at using our experiences to get better, otherwise they are just experiences and nothing else."
The Bulldogs will be back in action on Monday when they face Brown at noon on the Housatonic River.
Yale Boatings
Varsity Eight: 1. Colleen Maher, 2. Maddie Lips, 3. Natalie King, 4. Kim Szokol, 5. Nina Demmerle, 6. Claire Tolson, 7. Abbie Young, 8. Eliza Hastings, coxswain: Kristen Brownlee
Second Varsity Eight:
1. Kristjana Gudmundsson, 2. Abby Loucks, 3. Elizabeth Vincent, 4. Kristina Wagner, 5. Emily Tormey, 6. Amber Anderson, 7. Martha Cosgrove, 8. Madeline Dinse, coxswain: Christine Devlin
Varsity Four: 1. Mieke Scherpbier, 2. Natalie Lapides, 3. Juliet Caragianis, 4. Jen Stockwood, coxswain: Margaret Ayers
Second Varsity Four: 1. Kara Freeman, 2. Brit Sharon, 3. Mimi Reichenbach, 4. Amina Edwards, coxswain: Laura Grimbergen
Third Varsity Eight: 1. Sabrina Malak, 2. Jane Kozey, 3. Emily Diana, 4. Regan Considine, 5. Kendall Chapin, 6. Mary Farner, 7. Emma Hammarlund, 8. Christine Tsai,coxswain: Sarah Weil
Photo courtesy of David Hastings
Report filed by Tim Bennett, Yale Sports Publicity


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An LA prositute died, they didn't know what to write on her tombstone, so they wrote; finally she slept alone...
An LA prositute died, they didn't know what to write on her tombstone, so they wrote; finally she slept alone...
I met women the day before Christmas on her way to a Drug Rehab in Santa Barbara in the poring rain. The 30 minute ride to the hospital I learned that she has been brutally raped by three men and dumped behind a local hospital by the trash cans. It took 27 stitches to repair the damage from the gang rap. This is what I learned, her Heroin habit was feed by the many traumas she experienced, pancake upon another they feed her addiction with no one thing powerful enough to disturb the cycle. Her emotional pain drove her need to self medicate and the drug influence made it easy to be available to high risk situations. Her drug use caused mental health issues that finally dragged her back into the streets. She drifted out of my life as her legal problems caused her to place into custody. This is the heartbreak; she was a wonderful, sweet, funny and intelligent woman. My family embraced her and for the brief time she shared my home we loved her. Drugs are modern day slavery.
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August 31, 2012 06:00pm-09:00pm
Honolulu Museum of Art
'Beat the Heat' information
Step into liquid at ARTafterDARK: Beat the Heat, highlighting the exhibition Boardshorts: A Perfect Fit.
Sponsored by KAHALA.
Visit the KAHALA booth in Central Courtyard for special giveaways!
ARTafterDARK admission: $10. Free for Museum members.
Alex Purring sets a lounging tone, 6:15-7:45pm
Surf rockers Kalani and the Cruisers take the main stage, 6:45-8:45pm
Video artist VIZ latest sound-and-vision digital piece is inspired for surf and sand.
Zip Tours + ?art
Take a tour of Boardshorts: A Perfect Fit (meet docents inside the gallery) and participate in ?art activities for a chance to win prizes from our sponsor KAHALA.
Doris AfterDark
Head to the Doris Duke Theatre to see a special 9pm screening of Blue Crush.
Cool down with refreshing fare from Town and Downtown.
Just a reminder—ARTafterDARKers can park in the following locations:
1) FREE: Street parking on Beretania and Kinau Street from 6pm.
2) $4: The Pro Park Parking Lot behind the Art Center at Linekona, entrances on Beretania and Young streets Payment is to be made at the yellow slot box next to the parking booth.
3) $5 at the First United Methodist Church Parking Lot on the corner of Beretania and Victoria streets. NOTE: Lot closes promptly at 10pm.
4) $5 at Kim Chee III Parking Lot on Young Street


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Angela Andrade Perez is currently attending the United Nations Framework Convention on Climate Change (UNFCCC) meeting in Bonn Germany. Today she blogs about a side event on agriculture and climate change — an event presented by CI, Humane Society International, Woods Hole Research Center, Environmental Defense Fund, Environmental Monitoring Group and the Union of Concerned Scientists.
How the UNFCCC will address agriculture — an issue not only critical to our food security, but the future of life on our planet — hangs in the balance. After two weeks of negotiations here in Bonn, country delegates were unable to resolve their differences and decided to take the issue up again at the 18th Conference of the Parties (COP 18) in Doha later this year.
Currently, 20 percent of global greenhouse gas emissions come from agriculture. Countries have been trying to decide on measures to enhance emissions reduction for several years. Progress was made last year when they decided to take the issue up on more technological grounds, giving them the opportunity to address not only agriculture's mitigation potential, but also the need to help farmers adapt their practices in the face of climate change impacts. These impacts include increased frequency of droughts and flooding, and rising temperatures that are damaging the watersheds and other ecosystem services that sustainable agriculture depends on.
Earlier this week, I participated in a side event on the opportunities for supporting mitigation, adaptation and social goals in relation to agriculture in the climate change negotiations. Back home in Colombia, I work on many different elements of adaptation; figuring out how to support farmers in a changing climate is an essential piece of the puzzle. At the event, I discussed two CI efforts: my work with partners in Colombia in the Chingaza Massif highland ecosystems, and work that Conservation South Africa is doing in Namaqualand.
Through the Integrated National Adaptation Project in Colombia, we are working with local farmers to:
- Promote agroforestry, soil erosion control, home gardens and farm management plans to increase local agriculture resilience;
- Raise community awareness about the need to adapt in the face of changing temperatures and water availability;
- Use new technologies like rainwater harvesting, drip irrigation and wastewater treatment and recycling to increase resilience; and
- Restore important high-altitude grassland systems that collect and filter massive amounts of water later used for agriculture and other human needs.
A continent away, South Africa's Succulent Karoo is a semi-arid biodiversity hotspot that is particularly vulnerable to water scarcity, which will only to be exacerbated by climate change. Conservation South Africa is working to:
- Reduce climate change impacts and vulnerability by restoring wetlands and grazing lands within catchment areas;
- Implement sustainable livestock management actions, including removing invasive alien plant species;
- Reduce soil-damaging techniques by working with small-scale and commercial farmers through a stewardship approach; and
- Engage with local communities and government authorities to develop policies and plans that support an ecosystem-based approach to adaptation and sustainable development.
In order to effectively reduce vulnerability to and impacts of climate change, it is critical that adaptation actions are implemented at the farm level. The main goal should be not only to ensure food security, but also to maintain rural landscapes in order to guarantee provision of ecosystem services and the well-being of local populations. This holistic approach will help to reduce secondary impacts that come when a land is too degraded to support its people, such as decreased standards of living for small farmers and migration.
Adaptation and mitigation efforts must be implemented in an integrated manner. In addition to developing indicators to measure climate change resilience at the farm level, other supporting measures have to be taken into account, such as participative research, capacity-building, land-use planning and institutional development — especially at the local level. National policies must consider small-scale agriculture, especially in areas that provide services such as water provision and regulation. For example, development in watersheds needs to take into consideration the importance of the watershed's services for farmers downstream. Interlinkages between rural and urban areas are critical in effective agricultural adaptation and have to be considered.
Despite the current impasse in the negotiations, I am hopeful that discussions under the UNFCCC will continue to evolve. They should include the need to support local farmers while taking into account the larger systems that the farmers rely upon. This approach will ensure that farmers' actions reduce agriculture's impact on our global climate, and that the farmers in turn are more resilient to climate impacts.
Angela Andrade Perez is the environmental policy coordinator and manager of the Integrated National Adaptation Project (INAP) at CI-Colombia.


text:
Veni, Vidi, Sust�nui
Picture, in your mind's eye, a testudo.
If you're up on your Roman history, you'll know that I'm referring to that ancient Roman formation in which soldiers tightly align their shields to protect themselves from every angle as they advance. Even without the immortalizing effect of Asterix comics, the testudo remains an enduring icon of Roman military power, but it also serves as an apt analogy for the state of Total War: Rome II.
Indeed, the testudo is large, densely-packed, deadly effective, glorious to behold, and in the heat of battle, seemingly unassailable. At the same time, the testudo -- and Rome II like it -- is slow to move, unwieldy, and when scrutinized closely, reveals a number of vulnerabilities and gaps in the defense.
Total War: Rome II (PC)
Developer: The Creative Assembly
Publisher: Sega
Release: September 3, 2013
Reviewer's Rig: Intel Core i7 920 (2.66GHz), 6GB RAM, Nvidia GeForce 560 ti (Min. Specs here)
First off, any Total War fan wondering if The Creative Assembly has made any fundamental changes to the series' core formula shouldn't worry: Rome II is as much a Total War game as any that have come before, once again delivering that hybrid of turn-based strategic empire management and real-time tactical army battles that form the basis of the franchise's identity.
Also being a sequel to the original Rome: Total War, my favorite entry in the series (barring Shogun 2), the game once again allows you to take charge of one of nine major powers (twelve if you pre-ordered) and, by hook or by crook, conquer the known world. Yes, despite the existence of "Cultural" and "Economic" victory conditions, this is no Civilization game. The series is called Total War for a reason, so strictly dovish would-be imperatores need not apply.
Rather than true sea changes, Rome II instead implements many smaller, iterative improvements that streamline some of the longstanding pet peeves that have plagued the series, while layering on new systems to greatly increase the game's depth and scope. Because the truth of the matter is, despite its name, Rome II is about more than Rome itself.
Instead, Creative Assembly have put together something of a military-minded classical period simulator. The game's playable (and non-playable) powers range from all over Europe to North Africa and the Near East, covering four broad cultural groupings (Latin, Hellenic, Barbarian, and Eastern). The unit roster is practically a who's who of iconic warriors from the ancient world. Mid-Republican manipular legions, woad-painted berserkers, Spartan Hoplite phalanxes, Carthaginian war elephants, Egyptian camel cavalry, and more will all crash against each other in large blobs of slaughter on the real-time battlefields. And it helps that Rome II has made getting to those moments of glory comparatively easier, thanks to a host of updates to the UI and an improved approach to strategic management.
In fact, if the last Total War game you played was Rome (or perhaps even Shogun 2), the various changes Creative Assembly has wrought for Rome II expose a potentially uncomfortable truth about the series' strategic component: That much of it essentially amounts to busywork.
The most significant single change on Rome II's strategic layer acts to condense the traditional management of conquered and annexed regions by "bundling" groups of regions into "provinces." For example, the city of Rome herself belongs to the province of Italia, which consists of Rome, along with Neapolis, Velathri, and Ariminum. All four settlements are shown on a single pane, allowing you to manage their building makeup and taxation as a single entity. When every settlement in a region is owned by the same player, special "Edicts" can be enacted to provide ongoing bonuses to things like public order, tax revenue, growth, or other benefits.
Really, the provincial system is a minor tweak, but it does much to streamline the "management creep" that tends to affect these types of sprawling, map-conquest games. Rather than clicking on eight regions separately to issue orders, you're instead tabbing through two pages on Rome II's well-condensed central tab, briefly pausing to bring up a tooltip, or summoning a dense encyclopedia for more detailed mechanical help. Additionally, the system adds new strategic considerations, since provinces can only be managed as a whole if one faction owns every settlement within. You'll find yourself agonizing over whether to antagonize otherwise peaceful neighbors because their ownership of a settlement prevents you from "completing" some provinces. My apologies to the Carthaginians and Spartans. You were all put to the sword because I wanted to declare Magna Graecia to be one big party for a decade or two.
Other alterations also serve to tighten the experience of mustering and moving armies and fleets. Units can be recruited from anywhere within an owned province, eliminating the old "ant lines" of individual units marching from all across the map to join armies at the front. Moving land forces across water is a snap as well, since armies automatically spawn their own (unarmed) transports when ordered into the drink, and allowing you to say goodbye to the single-ship "mule fleet" of old. A "stance" system allows you to set armies to different postures, aligned for ambushes, defensive forts, or forced marches, giving more dynamism to a typical campaign.
Rome II also takes steps to distance its armies and fleets from being generic by expanding the RPG-like character progression Shogun 2 used on its agents to encompass most aspects of the game. In addition to the traditional level-up process and the acquisition of traits, army and fleet leaders can "equip" members of their household to gain more bonuses, not unlike slotting gems in a socketed Diablo III weapon. Even the armies themselves can gain traits as they fight, developing traditions, history, specializations, and even unique capacities. Oh, and they also get their own semi-random names (which can be customized at your discretion).
The result is an ancient world that feels simultaneously sprawling and intimate. The whole map is open to you, to conquer with the aid of your most trusted subordinates, and your most decorated and venerable Legions. The feeling of emergent "story generation" feels almost like XCOM, except on the scale of armies rather than squads and individuals.
This all sounds wondrous on paper, but in execution, Rome II's attempts to breath more life into conquest feel a bit too prosaic for their own good. Most traits, household items, and skills convey limp mathematical benefits rather than the dramatic differences their flavor text and stylized iconography imply.
Creative Assembly's attempt to simulate the perils of classical politics also falls flat, thanks to an utterly opaque "Faction" system. Replacing the family tree of Shogun 2, the faction system attempts to replicate the wheeling, dealing, and influence trading on the Senate floor (or royal court, if your faction's a monarchy). It's an intriguing idea, but I'll be damned if I can get it to do something I understand.
In theory, you should be watching out for overly ambitious generals and admirals, walking the thin line between celebrating their accomplishments and checking their rebellious tendencies. In theory, this would also be the system through which a Roman Republic might become a Roman Empire (and vice-versa). But in practice, the results of your manipulations feel insubstantial, or even contradictory, such as when some political gambits deliver the opposite result from the one predicted by the game's tooltips.
The same vagueness affects diplomatic dealings with other factions. Though the game surfaces more information than ever about how exactly your faction influences a neighbor or rival, little of it ends up being of use to bend towards practical results, like trade agreements, alliances, or vassalage.
Thankfully, the complexities and missed opportunities of the strategic layer haven't quite dampened Rome II's bloody-minded other half: Its real-time tactical battles. "More" is the operative word to describe what Creative Assembly has added. Rome II has more units, larger maps, more details, more particle effects, and most importantly, more approaches to the totality of ancient warfare. That totality now includes the most heavily advertised addition to Rome II's battles: Amphibious attacks. Now friendly fleets can assist ground-pounders by landing troops onshore in real time.
And it all looks stunning, to boot. Even years ago the quality of Shogun 2 seemed able to match those of a mid-range shooter, but Rome II ups the ante with complex facial expressions, individualized details, and a new "cinematic camera" that allows for direct control of things like siege equipment, for that extra bit of drama.
The game's AI -- always a point of contention for players -- has received an upgrade, but perhaps not one as substantial as is needed to truly satisfy series veterans. Though I'm rather incompetent when it comes to most games of this type, even I could tell that the AI has grown more reactive, but also increased in stubbornness, almost to the point of passivity. It's less vulnerable to being baited out of formation (though it can still be done), but seemed less likely to take advantage of opportunities. At one point the AI was reticent enough to simply wait and let me make the first move ... during a siege assault it started. Strategically, the AI had a tendency to throw tiny armies at my massive forces without a hope of winning, particularly once I had taken their last province. These kamikaze-like attacks were rarely disruptive to the play experience, but did lead to me clicking "autoresolve" more often than was necessary.
But alas, dear reader, the fault is not in our stars, nor in ourselves, but in Rome II's technical state. While it's not quite in the "half-baked" state some critics asserted at launch, Rome II is about as rough-hewn as a Woad Berserker's wooden shield, and one worries that between this and Empire, we may have witnessed the limit of Creative Assembly's ability to execute on its ambitions.
Performance was all over the board for my rig, despite favorable reports from the built-in benchmarking sequence. Perhaps the greatest offender was just how damned long it takes to simply resolve a turn, with the game cycling through dozens and dozens of NPC factions to process their actions. Even with "Show AI Turns" checked off, an early-game turn of Rome II took longer to end than a endgame turn of Shogun 2 at its most crowded. We're talking on the scale of minutes, in some instances.
The problem is exacerbated, ironically, by the very changes Rome II makes to speed up play. The provincial system and the streamlining of army movement and mustering revealed that much of a pre-Total War: Rome II game consists of "maintenance" actions, but the result is a goodly number of turns, particularly in the early game, are spent simply clicking the "End Turn" button and waiting for the endless scroll of AI processing to pass through again.
Having written that, most of Rome II's issues aren't related to the design of the game, but to glitches and poor optimization. In fact, three major patches have been released to date (and form part of the reason I delayed writing this final review), and significantly improved performance in multiple aspects of the game, including framerate, AI quirks, and even some tweaks designed to slow down the pace of battles in response to player feedback.
All the same, despite the improvements, the patches haven't quite mitigated the concerns expressed above. But it is easy to imagine a point, perhaps soon, when most, if not all of the kinks have been patched out and the waiting times cut down, leaving players with Total War: Rome II its best: a game that can actually make good on claiming "epic" scale and delivering a truly grand strategic experience coupled with blockbuster production values and satisfying tactical challenges.
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Total War: Rome II reviewed by Josh Tolentino
Solid and definitely has an audience. There could be some hard-to-ignore faults, but the experience is fun.
How we score: The Destructoid reviews guide


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March 15, 2008
SANTA BARBARA, Calif. -
The UC Santa Barbara women's tennis team continued its homestand this afternoon losing to conference foe Cal State Northride, 5-2. With the loss the Gauchos fall to 6-7 overall and 2-2 in Big West play.
The Gauchos opened doubles play the way you aspire to, winning the first match at No. 3. Senior Brittany Kausen and sophomore Tova Hausmen posted an 8-4 victory over Nina Jaworowski and Sandra Kukla to give UCSB the early advantage. The lead was short lived for the Gauchos as the Matadors scored victories at No. 1 and No. 2 doubles. Cal State Northridge evened the score when Victoria Brymer and Canna Furuta took down the Gauchos top pair of Marta Simic and Charlotte Scatliffe, 9-7. The Matadors clinched the doubles point with an 8-5 win at the No. 2 doubles slot.
The Gauchos did not fare much better in singles action, dropping four of six singles matches. The lone victories for UCSB came at the No. 1 and No. 2 singles spots respectively. Marta Simic avenged her doubles loss with a 6-1, 7-6 decision over Brymer. At No. 2 doubles, Jill Damion closed out the match by defeating Koichumanova 6-3, 4-6, 6-3.
UCSB will now break for final exams and return to action for alumni day on March 22nd. The Gauchos resume dual match play March 26th when they host No. 43 Boise State. First serve at the Rob Gym Tennis Court is set for 1:30 p.m. (PT).
Cal State Northridge 5, UC Santa Barbara 2
Complete results listed below.
No. 1 Marta Simic (UCSB) def. Victoria Brymer (CSUN) 6-1, 7-6
No. 2 Jill Damion (UCSB) def. Kanykey Koichumanova (CSUN) 6-3, 4-6, 6-3
No. 3 Canna Furuta (CSUN) def. Charlotte Scatliffe (UCSB) 7-6, 7-6
No. 4 Sandra Kukla (CSUN) def. Asagi Onaga (UCSB) 6-1, 6-3
No. 5 Brook Doane (CSUN) def. Tova Hausman (UCSB) 6-4, 6-3
No. 6 Nina Jaworowski (CSUN) def. Brittany Kausen (UCSB) 6-3, 6-3
Order of finish: 5, 4, 3, 1, 6, 2
No. 1 Brymer/Furuta (CSUN) def. Simic/Scatliffe 9-7
No. 2 Koichumanova/Doane (CSUN) def. Damion/Onaga 8-5
No. 3 Hausman/Kausen (UCSB) def. Kukla/Jaworowski 8-4
Order of finish: 3, 1, 2


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Why it's a good idea to wear a full-face helmet:
Poor focus due to the cell phone camera ... you can't really tell, but those are some really deep gouges where the patient's chin would have been. He might not have a jaw left if it weren't for the helmet. As it is he walked away with only a minor ankle fracture.
Well, he didn't "walk" away. More like hobbled away. You get the idea.
24 October 2007
Reason Number 23
Why it's a good idea to wear a full-face helmet:
Posted by shadowfax at 10:00 AM
1 comment:
Subscribe to: Post Comments (Atom)


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Thursday, October 25, 2007
R13 close, honestly!
I'm very close to releasing R13, I've just been struggling to find the time to add the final finishing touches to the savestate support. I've found it hard to get into a regular working pattern since moving, so what should have been a 1 week job has ended up taking a month. Bioshock and Halo 3 haven't helped either.
Savestates are working very well. The current implementation provides 10 slots which are shared across all roms. You can save to any slot at any time from an option on the Pause menu, or choose to reload a previous savestate. In this way it works just like QuickSave/QuickLoad found in various PC games (I'm tempted to add a special slot for this to the top level of the Pause menu).
I use zlib to compress the savestates, so an 8MiB savestate compresses down to 1MiB (or even smaller if you're running games which don't use the Expansion Pak).
There are just a couple of things I need to finish off now before I can release. Firstly I need to check if the savestate you're loading is for a different rom than is currently loaded. If this is the case I need to scan through your available roms looking for the correct one, and load it. To make this efficient I need to get the RomDB which I use for the PC build working on the PSP.
The second thing I need to do is come up with a decent way of linking some metadata to the savestate so I can show this in the UI. Just simple stuff like the full name of the rom, time the savestate was created and the total time spent playing when it was created. I figure without this information it'll be quite difficult to figure out what it stored in each savestate slot. The alternative is to add a text entry system to the UI so you can name each savestate, but I think this will just delay things even more.
In summary R13 is really close and I've not forgotten about it. Just a few more things to sort out and it'll be ready for release.
37 comments:
- mbeck said...
Great to hear from you again! Don't worry about when r13 is released, just make it the best it can be. I'm looking forward to seeing all your hard work in action! Keep it up :)
- Thu Oct 25, 12:33:00 pm BST
- John said...
Thats great news. I noticed in your other posts that R13 will be reasnably faster than R12. I was just wondering how much faster will it be and will it be able to run super mario 64 at full speed without sound? Because it is very close in R12.
Thanks and keep up the great work.
- Thu Oct 25, 02:03:00 pm BST
- shuaib said...
This so cool! Dude i've been waittinnnnnng for this loooong time.. :D
- Thu Oct 25, 02:16:00 pm BST
- Samuel said...
Yeah, you panic us sometimes, strmn_nrmn, but we love you anyways.
- Thu Oct 25, 03:11:00 pm BST
- Nico said...
Good to have you back!
You've lately talked about the new implementation of "savestate", but before that, you made some optimizations that gave you a series of speedups.
So, besides the savestate, how much faster is R13 from R12? And also, what is your next goal to focus on? Sound? Speed? Compatibility?
- Thu Oct 25, 03:30:00 pm BST
- Danny said...
Nice one strmn :)
Can't wait for the release :)
- Thu Oct 25, 04:22:00 pm BST
- Austin said...
Yay...Great to finally hear an update! =]
(I was really starting to worry.)
But that is a good thing you took your time cause I don't want to use up 8MB every save 0_0
IMB seems much much better
- Thu Oct 25, 05:25:00 pm BST
- AgentSmith said...
First I'd like to say that I love this project your doing - your work is very much appreciated and enjoyed, Thanks you are da man! Second I'd like to say that this is also very much worth the wait and will always be highly anticipated by the gaming communities - to have a working N64 Emulator on the PSP is incredible, I am hoping for a much needed speed increase so roms can be tested and/or played at a normal speed level (No disrespect in that statement, just hoping.) I would use this emulator for hours and hours because I have a lot of favorite N64 games that I love to play still, even after all these years. Anyways I do thank you for your great work, I will always be a huge fan of yours!! Later - Alan
- Thu Oct 25, 06:40:00 pm BST
- AlphA said...
Thank you! I'm so eager for DR13! Any news on better sound support though?
- Thu Oct 25, 06:45:00 pm BST
- Erik said...
Yeah! It feels really good to hear from you again! I just can't wait to try the new build! :-D
Good luck!
- Thu Oct 25, 07:32:00 pm BST
- roelandb said...
how about speed improvements for the new version?
- Thu Oct 25, 07:47:00 pm BST
- Jess said...
I can't wait for the release. Thanks for your hard work.
- Thu Oct 25, 08:08:00 pm BST
- Martin said...
Thankyou for the update and all the time and effort you put into your work.
I can't wait to see the differences in R13. I know you're a long way off perfecting it but it's great to experience the evolution process, one step at a time.
Keep us informed.
- Thu Oct 25, 09:40:00 pm BST
- Jody said...
What retard would name their savestates? Thanks for not forgetting R13 and keeping up with the monthly updates. If I ever have loads amount of money, I'll send you a donation. Love your work, Nrmn!
- Thu Oct 25, 09:57:00 pm BST
- BrendanL said...
My gosh! You scared me StrmnNrmn! I thought you died or something seeing as it was expected to be released about three weeks ago.
- Thu Oct 25, 11:47:00 pm BST
- Yann said...
You are a perfectionnist. You could perfectly release a version of Daedalus without the Candy. Of course, it is less perfect, but the other gains you made are really well worth a version number.
Oh well, you're the master
- Thu Oct 25, 11:48:00 pm BST
- Radamanthys2007 said...
Vc eh foda mano.... parabéns!!!!
Good Luck! You is the best!!!
I want Mario in the psp!!!!!!
- Thu Oct 25, 11:55:00 pm BST
- Mark said...
You rock!
- Fri Oct 26, 01:44:00 am BST
- Sr. Moska said...
great news, and I don't want to sound like I don't apreciate what have you done, but I think, that I'm more interested in a full speed emulator than in savestates
keep the good work!
- Fri Oct 26, 02:35:00 am BST
- Alexander said...
Thank you very much! I'd profess my live for you.. but sure as hell you're a guy so tough luck!!
keep up the good work!
- Fri Oct 26, 04:48:00 am BST
- givemelove said...
man, it's so good to hear you're still on track! I can't wait to try your new functionnalities on Daedalus.
Great Job.
PS: Forget about your xbox 360!!!!
- Fri Oct 26, 10:53:00 am BST
- Desaster said...
And what is about speed?
- Fri Oct 26, 04:25:00 pm BST
- Silent said...
keep on going dude :)
- Fri Oct 26, 10:13:00 pm BST
Any further optimizations since the last time you told us you've gained up to 20% or something, or have you been solely working on save states now?
- Fri Oct 26, 10:18:00 pm BST
- Swaa said...
You are a master, thanks for your work and sorry from getting nervous....
- Fri Oct 26, 11:27:00 pm BST
THanks for all that you have already done for all us retro gamers. Looking back at some of the different forum posts over the web about some of your earlier builds, since then you have already achieved so much that everyone said was impossible on the psp due to hardware limitations. Keep on proving em wrong.
- Sat Oct 27, 12:12:00 am BST
- Jun said...
Hey StrmnNrmn thanks for all the time u've spent on this. Ill be looking forward to the release.
Good luck!
- Sat Oct 27, 04:56:00 am BST
- Christian Lachner said...
Great work! Hmm, screenshot support would be nice for the savestate handler :). Is this on the "willBeAddedIfThereIsEnoughTimeSomewhereInTheFuture"-list?
- Sat Oct 27, 10:34:00 am BST
- brandon14 said...
I can't wait for R13. Savestate is a pretty big feature.
- Sat Oct 27, 03:07:00 pm BST
- Out of this Blog said...
Keep up the good work! ;)
- Sat Oct 27, 04:06:00 pm BST
- billy said...
:)good to hear from you man, you was worrying me i didnt know if somthing happend to you or not.
Anyways keep up the good work :D
- Sat Oct 27, 09:03:00 pm BST
- Jason said...
Awesome, keep it up and thanks for all your hard work and dedication!
- Sun Oct 28, 03:12:00 am GMT
- xSaVaGe said...
Is that all there is on the R13 so far or have you forgotten to post Speed Dynaric, ect. and whatabout the slim will that get an update or is it gonna be one update until you get a slim? I cant wait for this release cause it looks like you worked on this one for a long period of time. Nice Jod on Savestates they really become useful at times. Oh and what about the Turok Series will you ever get to them in your next update or even R15? I was wondering because they really shouldnt be hard to fix.
- Sun Oct 28, 05:46:00 am GMT
- Carlos said...
Nice, I was wondering where you had gone to xD. Actually, you do deserve a break, what you do isn't easy stuff. I can't wait for R13, hopefully zelda has those texture issues fixed and starcraft64(loads at least), I myself code but I am sure I am nowhere near your level but I might go ahead and try and get those two games to work if they don't.
- Sun Oct 28, 09:58:00 pm GMT
- Travis said...
is there an estimated day it will be released?
- Mon Oct 29, 03:58:00 am GMT
- David said...
Hey StrnmNrmn, thanks for the update and KEEP UP THE GREAT WORK! Life gets in the way, we all know, but thanks for letting us know that R13 is near completion. Thank you and good luck!
- Mon Oct 29, 02:08:00 pm GMT
- Diskun said...
First: Thank you for your hard work. We're really looking forward to see R13 as soon as possible.
Second: May I suggest you something rather stupid but very simple? Use a plain text file to store metadata and a savegame file both named just like the ROM.
ROM: ROMS/supersmashb.bin
SAVE 1: SAVES/supersmashb_1.sav
META 1: SAVES/supersmashb_1.met
SAVE 2: SAVES/supersmashb_2.sav
META 2: SAVES/supersmashb_2.met
So when you load the rom, you scan the SAVE directory for savestates, and then load the metadata MET files to show on the save list.
This may sound just lame, but is easier than creating your own savegame format and embedding the metadata in it.
- Mon Oct 29, 08:23:00 pm GMT


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CHICAGO -- Change was afoot at the 2010 Club Industry Conference and Exposition last month. The show was a day shorter, the keynote addresses started a bit earlier in the day, the welcome reception moved off-site and attendees had access to new technology to help them around the exhibit hall.
But all of that change was overshadowed by one man — Richard Simmons — who has been a staple in the fitness industry for years. Simmons offered a shot of excitement for the 550 attendees who packed the room to hear his first-day keynote. Simmons called people onto the stage to work out with him before he settled down to speak, vacillating between humor and tears in his presentation.
Before he opened his own club, Slimmons in Beverly Hills, CA, Simmons had been an overweight teenager in New Orleans and had tried to lose weight using unhealthy methods, he recounted.
"I hated being fat more than anything," he said as he tried to hold back tears.
Simmons commended the club operators and trainers in the room for the work that they do. He even said a little prayer asking for guidance for the audience.
"I have one piece of advice to give my peers and fellow club owners," Simmons said. "Know no strangers. Make everyone in your club feel like a million dollars. I hug people and tell them that they can do it. I tell them that I want them to come back at least three days a week, and they do."
Prior to Simmons' keynote, Curt Beusman accepted his Lifetime Achievement Award. Beusman founded Saw Mill Club, Mount Kisco, NY, in 1970, and he mentored many club operators during his years in the business. He also was a popular speaker at industry conferences, best known for his "Ten Commandments" speech. He revived that speech at the Club Industry show, jumping into character as "Brother Beusman" to rant and rave about the industry.
The second-day keynoter, Bill Rancic, was a bit less theatrical in his presentation but just as entertaining and informative. Rancic, the first winner of NBC's "The Apprentice," shared with attendees the story of his journey to become a businessman, including his childhood stint running a quasi-covert pancake business out of his grandmother's house, his cigar-of-the-month club, his experience as Donald Trump's apprentice and his many business ventures since then.
Rancic attributed his win on "The Apprentice" to practical execution, agility and risk taking. He also said that the successful people he's worked with and admired are creative, are good at making decisions and never quit or make excuses.
No excuses were necessary for the opening night reception. To celebrate the 25th anniversary of the trade show, show organizers moved the welcome reception from its usual location at McCormick Place to the House of Blues Chicago. Approximately 400 people attended the reception.
"The House of Blues is a Chicago landmark, and locating our reception there really set the tone for a great evening of networking and fun," Zari Stahl, group show director for Club Industry, says. "It was the first time I can remember that the Club Industry reception was held somewhere besides the convention center or show hotel. Judging from the turnout and the comments we heard, it was a big hit with the audience."
Winners of the Best of the Best competition also had reason to celebrate. The winners picked up their awards at the Business Breakthrough Brunch, which was attended by about 65 people. Sandy Coffman, owner of Programming for Profit, and Eddie Tock, owner of Eddie Tock Consultants and a partner in REX Roundtables, had judged several of the categories and shared their thoughts on why these programs won. (Read the October story "Models of Success" for details about the winning programs.)
Staff from eight other club companies participated in the Group X Gallery competition, which was held in the Club Studio. Representatives from the clubs showed off one of their club's original group exercise programs. Each of the clubs in the competition received a plaque for participating.
Making participation in the show easier this year was a new mobile application that allowed attendees to access information about the show, schedule their seminars and locate exhibitors. Thanks to sponsors Retention Management, Precor and Paramount Acceptance, the mobile application was free. It will be rolled into an application for Club Industry magazine and for future Club Industry trade shows.
"The new show schedule was a 'win-win' for everyone, making it more convenient and cost-effective for fitness professionals and suppliers alike," Stahl says. "By right-sizing the hours, we were able to provide as much — or even more — information in less time and still offer more than enough time on the exhibit floor as well."
Plans are already under way for next year's show, Oct. 12-14 at McCormick Place in Chicago. The former Club Industry East show, now known as Club Industry Executive Summit, will be May 11-12, 2011, in New York.


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La Tua Cantante
As usual, this will come in two parts: Edward's pov and Bella's, but the first is always Bella's. I got this idea from watching Buffy the Vampire Slayer, when Angel got shot with a poisoned arrow and has to drink Buffy's blood to survive. This is pretty much mid-Eclipse and the Volturi infected Edward with a disease called "Distruzione" (Italian for "Destruction") which only affects vampires and he will die unless he drinks the blood of his la tua cantante, which is Bella. This is just more hardships for Edward and Bella to fight through, but as always, they fight it together and never give up.
There are some adult-themed situations, so unfortunately this fanfic will have to be rated Adult instead of Everyone. Sorry to my younger fans, but please, exercise caution when reading this fanfic. It will get extremely detailed.
1. Chapter 1: Something Wrong
Rating 3.8/5 Word Count 1085 Review this Chapter
"Okay...so are you sure you don't mind my two-week trip with Billy to Michigan?" Charlie asked for the millionth time."Yes, Dad, I don't mind!" I said, irritably, "Go, fish, have fun; I'll be fine. I have been alone before."
"Yes, and it will stay that way, you hear me?" Charlie said, firmly, accusingly.
"I hear you, loud and clear. Edward will not breathe while you are away." I had to stifle a snort at the literal possibility of that.
"Don't...get smart with me, Bella. I do not want Edward anywhere near this house while I am gone--or you at his!" He added, as I opened my mouth.
"Come on, Dad. Why don't you trust me?""I trust you fine; it's him I don't trust."
I rolled my eyes, "Don't start with me. I'm not doing this again, Dad, you are being completely unreasonable."
A horn honked and I shoved him towards the door, "Go! I'll be fine. Have fun."
Charlie grimaced, but left nonetheless. I watched from the doorway, waving to them as they left.
Once the car disappeared around the corner, Edward's arms snaked around my waist from behind, pulling me into him.
I smiled and wrapped my arms around his, pulling them tighter around me. I tilted my head up slightly and nuzzled his neck. "Breaking the rules already, are we?" I smirked, not caring in the least what rules went broken anymore.
"Mm..." he kissed my jawbone lightly, "As if we haven't broken them all. I mean, I spend every night in your room."
"Yeah, well..." I spun around in his arms, wrapping mine around his waist, "What Charlie doesn't know...won't hurt him."
He rested his forehead against mine, "Ah, touche."
I wrapped one arm around his neck, buried my fingers in his hair and brought his head down to meet mine, crushing my lips to his, eager to be so alone with him.
He chuckled into my mouth and then spun me around, using my body to shut the door. He leaned me against it and I whimpered as he leaned in further to deepen the kiss. He placed one hand on the door beside my head, struggling to not break it with his fingertips.
"Mm..." I began trembling as he propped me in between his legs, squeezing my body between his thighs.
He tightened one arm around my waist, pressing me against him so there was no space between us, and grabbed one of my hands, slid our hands between our bodies, holding them to his chest, and then spun me around, dipping me gradually as he kissed me.
I arched my back and tilted my head back to deepen the kiss even more and my eyes fluttered open and shut in ecstasy.
I felt him suck gently on my bottom lip, before withdrawing it from in between his lips, and trailing his parted, trembling lips and the bridge of his nose, down my throat, sniffing in deeply. I probably should've been scared, but I couldn't bring myself to feel fear.
His lips, still parted, lightly pressed into the hollow of my throat and then he kissed it hungrily, pulling me even closer to him as he did so. He trailed his lips along my collarbone, up to the side of my neck, which he traced with his lips.
I then pulled his head up and reached my lips to his, desperate to taste as much of him as I could. He pulled me back up and walked us backwards over to the couch. He spun us around and threw me gently onto it before lowering himself on top of me, reaching his lips to mine immediately.
I pulled him even closer by the collar of his shirt and arched my back again, running my hands down his back and into his shirt, caressing his waist and lower back.
He began frenching my neck and I tilted my head back to give him better access, pressing myself further and further into him.
Was this really happening? If so, I hoped it never ended. I brought my hands around and traced the distinctions of his six-pack delicately with my fingertips, before timidly reaching for his belt to undo it.
As I suspected, he grabbed my hands and pulled away. But, when he looked at me, he looked pained.
"Edward?" I asked, breathlessly, shifting my weight underneath him to see him better. "Edward, what is it?"
Breathing even more raggedly than I was, Edward looked at me, smoothed out my hair on my face, kissed my lips softly, and said, so softly I barely heard him, "Bella...I...love you." Without warning, he collapsed off the couch onto the floor.
"EDWARD!" I knelt beside him and pulled his head into my lap, brushing his hair back, tracing his features with trembling fingers.
Did he fall unconscious? How was that possible? Was he sweating? I brushed a drop off his temple and gently shook him. "Edward? No. Edward. Edward. Edward. Edward. NO! Edward, can you hear me? Edward!"
No answer. He simply jostled weakly in my arms, his head lolling to the side.
My heart raced and tears flooded my eyes, streaming down my face. I couldn't lose him. Not again. I would not allow him to leave me again. There had to be an explanation for this.
Struggling greatly, I lifted one of his arms, wrapped it around my neck, and wrapped one of my arms tightly around his waist. Using all my strength, I managed to get him onto the couch, tripping several times, breaking random items, and knocking things over.
My legs were trembling so hard that I collapsed onto his chest weakly and sobbed hysterically. How could he be fine one second to practically dead the next? It didn't make sense.
Trembling so hard that it could have easily been mistaken for convulsions, I looked up at Edward and took his face in my hands. "Edward? Edward, please answer me. Edward!" I screamed out of pain and rage, "NO! Please...don't...not...come back to me."
Suddenly, I was being ripped away from Edward by Alice, who effortlessly carried me away.
"Bella, shh...it's going to be okay. Carlisle's here; everything will be okay. Calm down."
I hugged her so close that had roles been reversed, I would've been crushed. "Alice...I'm scared." I mumbled.
"I know, Bella." She assured me, comfortingly, "I know."
"Hold me," I pleaded, and she obliged merely holding me until I calmed down, rocking me back and forth slightly.
- Chapter 1: Something Wrong
- Chapter 2: Your Blood
- Chapter 3: Bloodlust
- Chapter 4: Appreciation
- Chapter 5: Proposal
- Chapter 6: Fear
- Chapter 7: Instability
- Chapter 8: Strength
- Chapter 9: Intimacies
- Chapter 10: Overwhelmed
- Chapter 11: Third Time's a Charm
- Chapter 12: Daring
- Chapter 13: Weakness
- Chapter 14: First Night
- Chapter 15: The Civil War
- Chapter 16: Scared
- Chapter 17: Dealings
- Chapter 18: Unrepentance
- Chapter 19: Comfort
- Author
- theocullenpadackles6012
- Rating
1 2 3 4 5
- Reviews
- 48
- Words
- 28648
- Views
- 1
- Published
- 22 Sep 08
- Updated
- 05 Jan 12
- Status
- Complete


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Universal Life Church Products for Ministers!
If you are a minister who wants to perform a ceremony, increase your education, or open a church, this is the place to come. We have supplies and services to help you in your quest to find your path.
Welcome to the ULC Online Store. Please look around and let us know what you think! More products being added regularly. We have a lot more clip on badges and cards for you to look at. New pictures, new products, great videos, etc. Check out our affiliation with the ULC Seminary program as well. We have a growing number of courses for you to explore. For your convenience, you may choose a product category from the top menu
We have many products to choose from and we usually ship within 2-3 business days. FedEx orders will ship within one business day, often the same day, if we can.
Since 1959, the Universal Life Church has remained headquartered in Modesto, California, and has congregations around the world. The sun never sets on the Universal Life Church. ULC ministers come from all walks of life and many spiritual traditions. We are all a part of Universal Life because of our belief in the universal doctrine, which is:
We believe everyone has the right and responsibility to find and follow their own path and determine for themselves what is right. As long as it doesn't infringe on the rights of others, it is not in conflict with the ULC doctrine. Along with this responsibility, each person bears responsibility for the consequences of the choices they make. Come celebrate truth, wisdom, and religious freedom with us here at the original and genuine Universal Life Church.


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Luiza Vizolis artwork has just been selected to be featured as set dressing for the feature film Draft Day starring Kevin Costner, Jennifer Garner and Frank Langella.
Luiza Vizolis painting Spring Bouquet will also be featured as the cover for The Old Farmers Almanac 2015 Engagement Calendar. The calendar is sold in US and Canada.
Luiza's Painting "CITY OF LIGHT" is on the cover of the 2011 "Breaking Bread"- the annual Catholic publication of the Oregon Catholic Press.
Luiza's Paintings in Delia's Mediterranean Grill and Brick Oven Pizza - Greek and Italian inspired cuisine.
Luiza's Painting in the Washington Post: You can see that one of my custom Olive Tree painting commissioned by the Delia's Mediterranean Restaurant in Alexandria,VA that was featured in the Washington Post on January 22, 2010.
Luiza's Paintings in the "McKee Homes" in Airdrie, Red Deer and Black Diamond in Alberta-Canada:23 paintings made by me were chosen to decorate the luxury McKee Homes for their showrooms. At ArtByLuizaVizoli, we enable customers from any country to buy the artwork of Luiza Vizoli without having to step outside their comfort zone. With us, you can browse through thousands of beautiful paintings brought to life by none other than Luiza Vizoli, at any hour, day or night.
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Our website brings all original paintings for sale the way they are supposed to be: without distractions or interruptions! We provide collectors, consultants, art buyers, interior designers and architects the opportunity to purchase and view original artwork by Luiza Vizoli.
Choose from several different types of art and fill your home and office area with creativity!
If you need further information regarding the paintings or have any other question in mind, contact us at email@example.com.
You can also ask for the price of the paintings (if not displayed) because the amount was too low to display!


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The Giant Sperm Whale
Did you know it is the male Sperm Whale that we see off the Kaikoura coastline all year round?
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Did you know it is the Giant Sperm Whale that we see off our coastline all year round? Being the largest of the toothed cetaceans they can measure in at up to 20 metres in length and weigh in at around 60 tonne in weight!
There are some amazing facts about the Sperm Whale that are worth sharing, showing you just how truly amazing these creatures are and in turn how incredibly blessed we are to be able to enter into their natural environment.
What do they eat?
• Sperm whales feed on large pelagic fish such as Hapuka (Groper), Ling, Tuna, Black Shark, King Fish but their preferred diet is squid.
• The Sperm Whale feeds on many different species of squid, including the exclusive Giant Squid.
• Despite frequent attempts by numerous scientists here in Kaikoura, the Giant Squid has only been viewed alive in its natural habitat off the coast of Japan.
• The Giant Squid grows to an average length of 12 metres, but has been known to grow to lengths of over 18 metres.
Echo Location:
As sound waves (clicks) pass through the spermaceti oil, the sound is enhanced and amplified. The Sperm Whale is thought to be one of the world's loudest animal. It has been recorded at 230 decibels. It is thought that the Sperm Whale can use its sonar not only to locate its prey but to stun or kill its prey.
Inside the Sperm Whales head:
• The Sperm Whale has the largest brain of any living animal. Their brain is approximately the size of a basketball, approximately 7 times larger than the human brain.
• Also inside the Sperm Whale's head is the spermaceti melon, containing around 2.5 tonnes of oil.
• Once thought to the sperm or semen, hence the name: Sperm Whale
• Once highly sought after for production of candles, cosmetics, lubrication of sewing machines and industrial machinery. Famous for use in Rolls Royce engines and gearboxes and early Apollo space missions.
• Possibly used by Sperm Whales to assist in echo location and/or buoyancy.
Deep Divers:
• The Sperm Whales off our coastline dive for 40-60 minutes to depths of up to 1000+ metres.
• The Sperm Whale is the deepest diving mammal in the world, diving for over 2 hours and over to 3000 metres.
• The Sperm Whale has 2-30 pairs of conical shaped teeth on their bottom jaw. The top jaw has sockets that the bottom teeth slide into when the mouth is closed.
• The Sperm Whale doesn't use teeth for chewing, but similar to the action of a crocodile, their jaw snaps shut and food is swallowed whole.
• Each tooth of the Sperm Whale can weigh up to 1 kilogram.
Life cycle:
• Male Sperm Whales spend the first 8-12 years of their life with the family pod in tropical waters.
• The females of the pod assist the calves for around 2 years until they are confident swimmers.
• When the males reach puberty, at around the age of 10 years, they leave the family pod forming bachelor pods and move to feeding grounds such as off the Kaikoura coast.
• Male Sperm Whales do not mate until this happens; the whales rarely leave the feeding grounds.
• Sperm whales can live for over 70 years.
Where can they be found?
• Sperm Whales are found in all the world's oceans, usually in submarine canyons of waters deeper than 400 metres.
• Sperm Whales can be viewed off the Kaikoura coast all year round.
• The Kaikoura Canyon is a feeding ground for male Sperm Whales.
• Male Sperm Whales have around 30-40 cms of blubber (fat) surrounding their vital organs. The blubber acts like a wetsuit, insulating the whales from the cold water. The temperature of the water is far too cold for the females as their layer of blubber isn't as thick.
• Female Sperm Whales usually inhabit the warmer waters near the tropics.
As you can see from the all this amazing information the Sperm Whales that we get to see on our tours are truly magnificent creatures!
We look forward to having you come join us - check out www.whalewatch.co.nz for more information


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September 23rd, 2013, 10:02 PM
Check here for ingredients in your favorite MAC products. Note: This is a moderated forum for the time being. Posts made to this forum will enter the moderation queue prior to appearing in the forum.
February 12th, 2014, 05:33 PM


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Random Walk: Twist Car Race
The halls of Thayer turned into a twist car racecourse for a final class exercise in ENGS 146: "Computer-Aided Mechanical Engineering Design." Propelled by rotating a steering mechanism from side to side, the cars tested students' design and fabrication skills. With one month from concept to race day, students mocked up wood prototypes, designed digital prototypes using SolidWorks software, fabricated their cars in the machine shop, and then wiggled their way around Thayer to see whose car worked best.
The project is about "teamwork, project management, mechanical design, technical communication, and the challenges of reducing theory to practice," says Professor Solomon Diamond '97 Th'98. "Culminating in a fun, competitive, and silly race makes it an engaging and memorable experience."
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Alumnus edits award-winning documentary
Sundance film guide describes it as "a masterpiece filled with hope and the potential to affect change"
May 1, 2012
By Maria Lovelette '13
As a computer geek at Saint John's University, Paul Frost never expected to make his mark in the film industry.
Yet in hindsight, the 2002 SJU graduate in computer science recognizes that his liberal arts experience laid the foundation for his career.
Frost is the editor of an award-winning documentary at the 2012 Sundance Film Festival. The festival showcases American-made films and highlights low-budget, independent films.
Frost's documentary, "The House I Live in," won the U.S. Documentary Grand Jury Prize and was described in the Sundance Film guide as "the definitive film on the failure of America's drug war."
The film guide also describes it as "a masterpiece filled with hope and the potential to affect change."
"The House I Live In" explores the deep issues regarding the 40-year War on Drugs, a campaign that has accounted for 45 million arrests in the United States. This film discusses the policies in the United States that have led to drugs being cheaper, purer and more available today than ever.
As a student, Frost immersed himself in different cultures through study abroad in Greece and Italy. He also spent a semester studying foreign language in Salzburg, Austria. After graduating from SJU, he continued his education at the Concordia language villages where he worked on editing videos with kids at the German language camp.
That experience sparked an interest in film-making and led to a six week program at The Edit Center in Manhattan, N.Y. These experiences helped prepare him for a career in film editing when Eugene Jarecki approached him to work on "The House I Live In."
Many of the courses Frost took at CSB and SJU also helped with that preparation by opening his mind to issues of social justice in the world.
"From the very start of my gender course, as well as the theology and Judeo Christian heritage courses, I found an environment that fostered open discussion of issues of social justice," he said. In relation to his time abroad, Frost said, "Spending a significant amount of time in a foreign country is one of the opportunities I value most about my liberal arts education at CSB and SJU, because it taught me to question policies and practices that I had long since accepted and that for many have become the status quo."
For Frost, the ability to question the status quo, combined with his commitment to social justice and his computer skills, enabled him to challenge a 40-year-old government policy.
"In working on The House I Live In, I came to realize that very often, it's not the horrific ends we should be on the lookout for, but rather the machinations that lead up to those ends.
"When I graduated from SJU with a computer science degree, I couldn't imagine that I would ever make a career of editing. Now I cannot imagine doing anything else."


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Men's Bridge
Location:Leaside United Church
Address:822 Millwood Ave Toronto Map
Start date:September 6, 2017
End date:June 13, 2018
Time:12:30 PM – 04:00 PM
For 20 years, a male-only group has been meeting on Wednesday afternoon's in Leaside. The quality of play is surpassed by the camaraderie, thus expertise is not as highly rated as one's sense of humour. What do we find appealing about Bridge? It is not for the pleasure of memorizing a bidding system or adhering to rules. The games appeal lies in problem solving. During a game, you face dozens of decisions, many of which require logical reasoning. This group is an all-male group. The cost is $3.00 per afternoon. We play four hands, then winners move to the next table. We play 24 hands from 12:30 to 3:30 PM. From 3:30 to 4:00 PM, we have coffee/tea and cookies together. Information: Jim Krafchik 416-488-7720 or email@example.com


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Dark Voices Vol. 4 is a collection of over 100 one shot vocal samples, easy to used for producing Techno, Electro, Drum & Bass, minimal in Dark Style.
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Underground Construction Magazine
Underground Construction is an important resource for any contractor, municipal manager or engineering professional involved in the construction, rehabilitation and remediation of underground pipeline systems. Coverage extends to the entire underground utilities infrastructure market including water/wastewater, oil, gas, telephone, cable & power. Each issue reports the latest news, technology and significant innovations available to industry professionals in managing the underground construction projects.
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Related Product Information
DETACHaBEAD CD19 is intended for detachment of Dynabeads from CD19+ cells after isolation with Dynabeads CD19 Pan B, cat. no. 111.43D (not supplied). The detached CD19+ cells are pure, viable, not activated by the detachment and have no Dynabeads with primary antibody bound to the surface.
Principle of Detachment
DETACHaBEAD CD19 is added to the bead-bound cells after isolation with Dynabeads CD19 Pan B. The DETACHa-BEAD CD19 reagent will detach the Dynabeads and primary antibody from the CD19+ cells. Dynabeads are subsequently removed using a Dynal magnet, and the detached CD19+ cells are ready for any downstream application.
Description of Materials
DETACHaBEAD CD19 contains polyclonal anti-Fab antibodies specific for the CD19 antibody on the Dynabeads CD19 Pan B. No cross-reaction with human IgG, IgM or IgA has been detected in quantitative ELISA tests.
Materials Supplied
- 5 ml DETACHaBEAD CD19 in 0.15 M phosphate buffered saline (PBS), pH 7.4.
Note: Due to the high protein concentration it is not unusual to see some precipitation in the DETACHaBEAD CD19 component. This will not influence on product performance or quality.
Additional Materials Required
Materials that are not included, but are needed to perform the entire protocol:
- Dynabeads CD19 Pan B (cat. no. 111.43D) for positive isolation of CD19+ cells.
- Magnet: See www.lifetechnologies.com/magnets-selection for magnet recommendations.
- Mixer allowing both tilting and rotation.
- Tubes: We recommend adapting the tube size to the working volume (e.g. using 1.5 ml Eppendorf tubes for small volumes).
- Medium, e.g. RPMI 1640 w/1% Foetal Bovine Serum (FBS).
Table 1: Volumes of Dynabeads CD19 Pan B, medium and DETACHaBEAD CD19.
|Volume Dynabeads CD19
Pan B used for cell isolation
|25 μl
| Volume medium to resuspend
bead-bounds cells (step 2)
|250 μl
|Volume DETACHaBEAD CD19
(step 3)
|10 μl
- Start with bead-bound cells after isolation with Dynabeads CD19 Pan B as recommended (i.e. use 25 μl of Dynabeads CD19 Pan B).
- Resuspend the bead-bound cells in 250 μl medium (never use less than 100 μl medium).
- Add 10 μl DETACHaBEAD CD19 per 25 μl Dynabeads used for cell isolation (never use less than 10 μl DETACHaBEAD CD19).
- Incubate for 45 min at room temperature with gentle mixing.
- To enhance the release of cells, pipette the solution a few times before placing the tube in the magnet for approx. 1 min.
- Transfer the supernatant containing the released cells to a new tube. To obtain residual cells, wash the beads 2-3 times in 500 μl medium and pool the supernatants.
- Wash the detached cells thoroughly by resuspending the cells in a total volume of 10 ml medium and centrifuge for 6 min at 400 x g to remove any residual DETACHaBEAD reagent.
- Resuspend the cells in medium and use in any downstream application. The isolated CD19+ cells are pure viable and are free from antibody or beads bound to the surface.
Note: To avoid cell loss when working with small volumes, we recommend to keep the suspension in the bottom of the tube while still providing good mixing
This product is stable until the expiry date stated on the label when stored unopened at 2-8°C. DO NOT FREEZE. Store opened vials at 2-8°C and avoid bacterial contamination.
Warnings And Limitations
This product is for research use only. Not for human or animal therapeutic or diagnostic use. Certificate of Analysis (CoA) is available upon request. Material Safety Data Sheet (MSDS) is available at
- Rasmussen AM, Smeland E, Erikstein BK, Caignault L and Funderud S. A new method for detachment of Dynabeads from positively selected B lymphocytes. J Immunol Methods 1992;146:195-202.
- Dryer RL and Covey LR (2006) Use of chromatin immuniprecipitation (ChlP) to detect transcription factor binding to highly homologous promoters in chromatin isolated from unstimulated and activated primary human B cells. Biol. Proced. Online;8(1):44-54.
- Døsen G et al (2006) Wnt expression and canonical Wnt signalling in human bone marrow B lymphopoiesis. BMC Immunology. www.biomedcentral.com/1471-2172/7/13.
- Ertesvag Aa et al (2007) Vitamin A potentiates CpG-mediated memory- B-cell proliferation and differentiation:
- involvement of early activation of p38MAPK. Blood 109(9):2865- 3872.
- Feederle R et al (2006) Epstein-Barr Virus BNRF1 Protein Allows Efficient Transfer from the Endosomal
- Compartment to the Nucleus of Primary B Lymphocytes. J. Virol. 80(19):9435-9443.
- Ryan EP et al (2005) Activated Human B Lymphocytes Express Cyclooxygenase-2 and Cyclooxygenase
- Inhibitors Attenuate Antibody Production. J Immunol. 174:2619-2626.
For Research Use Only. Not for use in diagnostic procedures.


text: Manufacturer: Cotton + Steel Collection: Magic Forest Designer: Sarah Watts Width: 44" Weight: quilting weight Content: 100% cotton Fabric is priced and sold by the 1/4 metre. We cut multiple 1/4 metres continuously. For example, if you select 4, your fabric will arrive cut as a single 1m piece. A single 1/4 metre will be cut as a fat quarter, unless otherwise requested.


text:
Reports said Tuesday that Obamacare got to the magic 7 million mark in completed signups by the time enrollment closed at midnight, and now the question is whether that figure could actually hit an even higher milestone once the stragglers are finally tallied.
White House Chief Technology Officer Todd Park was quoted by American Urban Radio Network White House correspondent April D. Ryan as telling workers that the 7 million mark was reached, offering President Barack Obama's signature legislative achievement some vindication after a rocky start six months ago. The Hill later picked up the news.
The difficult birth of the Affordable Care Act, in which the main enrollment website HealthCare.gov was mostly ineffective for the first two months, prompted government estimators to lower their projections on first-year signups to 6 million from 7 million.
But enrollment hit the 6 million mark last week with the heaviest enrollment days ahead. A crush of consumers flocking to the site over the weekend and on Monday meant that getting to 7 million seemed assured despite last-minute glitches on HealthCare.gov, many related to heavy traffic.
Now the question is whether those who started the process and will be allowed to finish after the deadline can push enrollment past another milestone.
Health and Human Services spokeswoman Joanne Peters tweeted early Tuesday that in all, there were 4.8 million visits to HealthCare.gov and nearly 2 million calls were made to call centers handling enrollment.
It's unclear, though, how many of those were repeat visitors and how many were unable to complete enrollment. HHS officials weren't immediately available for comment.
President Obama was scheduled to speak to reporters on the health-care initiative at 4:15 p.m. Eastern.
Follow Russ Britt on Twitter @russbrittmktw.
Follow Health Exchange on Twitter @MWHealthBlog.
More health-care news from MarketWatch:
A look at the last, tumultuous day of Obamacare signups
More last-minute troubles with HealthCare.gov