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Kathryn Heivilin, CPIA, RBP
Senior IACUC Manager
UM Biosafety Officer
Sanitation Strategies, Hygienic Solutions for Critical Environments
Last Review Date: November 20, 2017
I. Purpose
The purpose of this standard operating procedure is to have the most effective chemical sanitation program that encompasses support, communication, program safety, and mixing/application expertise.
- Improved vendor support
- Improved communication
- Enhanced safety
- Enhanced audit preparation
- Enhanced animal welfare
A. Sanitation Strategies will implement the AchieveClean program including 28 point
inspection on every service visit (4 times each calendar year). Cage Washer
operations and proportions will be examined and areas of concern will be
identified in a report and communicated to management.
- Improved facility operations
- Management will have a better awareness of washer operations and sanitation results
- Enhanced safety
B. Service reports will be available in the ServStar Sanitation Data Management
System for 24/7/365 access
- Trending can easily be charted for comparative purposes
- Audit preparation anxiety is reduced
- Disinfectant concentrations will be checked and reported each visit
- Effective, safe and reliable training program for employees reducing the potential for chemical accidents
- Reduced liability for the University of Montana
- Reduced chemical waste
- Sanitation Strategies will loan and install water driven proportioning equipment to facilitate
properand safe use of chemicals
- Sanitation Strategies will perform ATP testing of animal equipment exiting the washers and 28 point inspection process for all cage washing equipment.
- Sanitation Strategies owned equipment will be serviced and parts replaced at no charge to UM
- UM will purchase and use Sanitation Strategies detergents and supplies
- Cage washer equipment operation deficiencies will be noted in the service report for vendor service technicians
C. Detergents and Chemicals
LabSan256- proportioners LabSan230C-cage washer LabSanpH control-cage washer
II. Directions for Use: All LAR staff must have chemical detergent training
A. Personal Protective Equipment- staff must have a "spotter" when opening and
moving chemical drums to animal labs. Clipboard in HS009 office to check off
proper PPE and inventory of chemical. The following PPE must be worn and used
to move chemicals:
- Safety glasses/face mask
- Lab coat
- Gloves
- Barrel hand cart designed to secure 30-gallon barrels
B. First Aid: Safety Data Sheets (SDS) posted in HS010 and in SDS notebooks
- Wash hands thoroughly after handling
- If on skin, wash with soap and water
- Take off contaminated clothing and wash before reusing
- If in eyes, rinse eyes at eye wash station for 15-20 minutes. Seek medical attention if irritation persists
- Call 243-6131 to report a spill to Environmental Health Risk Management
- HS 010 has a spill kit for clean-up.
***Sanitation Strategies provides Serve/Train, an on-line training program for LAR staff, as well as an in-house training program annually


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Our tutors are experts and they're here to help guide our students learning journey. Our students find study results in gaining a new position, promotion or changing careers completely.
Call us to get more info 01 437 8559
Study more effectively from home or work with the practical advice available in our learning blog.

subset: commoncrawl


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If you follow any low carb diet like the keto diet, you will likely be tracking your daily net carb intake. Most people try to stay under 20-50 g of net carbs every day. To calculate this, nutrition facts labels are used to determine the number of net carbs per serving.
That sounds simple enough. However, you may be unknowingly consuming "hidden carbs" when you use nutrition labels for foods with small serving sizes. When a product has a label with a small serving size, it's more susceptible to rounding errors when you need to use multiple servings for a recipe.
A great example is heavy whipping cream, which typically has a nutrition facts label with a serving size of 1 tablespoon. Note that 1 tablespoon of heavy whipping cream has 0.41 g total carbs, according to the USDA's basic nutrient report.
Most product manufacturers will not list 0.41 g for total carbs on the label; instead, they will round down and list 0 g. As a result, many people will erroneously think that heavy whipping cream has zero carbs, which is not true.
If you need 1 cup of heavy whipping cream for a recipe, that would equate to 6.5 g carbs that you unknowingly consumed. That's nearly one-third of your daily carb allowance if you follow a strict 20 g keto diet.
That's why you should watch out for foods with small serving sizes listed on nutrition facts labels, especially if you need to use multiple servings. These "hidden carbs" add up, and can knock your body out of ketosis.
When in doubt, check if the food in question is available in the USDA database with a standard reference source (as opposed to a source from a branded label).
- Learn how to start a low carb diet in this comprehensive guide
- Check out low carb science studies to understand why this diet is good for you
- Download a printable low carb grocery list so you can start buying healthier groceries


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I have listed a new property at 2108 9357 SIMPSON DR NW in Edmonton.
TURN KEY UNIT in Terwillegar is ideal for those who are constantly on the go! Enter into a open and bright unit featuring a kitchen with new vinyl flooring, corner sink, glass tile back splash and stainless steel appliances. Rich tones with dark cabinetry with ample cupboard and counter space plus room for dedicated eating area. The living area has laminate flooring and a door leading out to a fenced in east facing patio - great if you have a small dog you need to let out. The master is spacious and includes a walk through closet and 4 pce ensuite. There is an additional bedroom and 4 piece bathroom. Includes in-suite laundry and storage area, plus energized parking stall right out side the patio door. Excellent location with great access to Anthony Henday or Whitemud. Easy to get to Edmonton International plus amenities. A great lifestyle choice!


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Flossing your teeth one a day is the most effective way to remove plaque and food particles from between teeth and along the gumline. While an effective flossing technique is important, there are other minor variations in dental floss that can be a factor. To help you choose the best type of dental floss for you and your family, your dentist, Dr. Keith Huff, offers these key insights.
Unwaxed dental floss is essentially a plain strand of monofilament or braided nylon that has not been treated with a waxy coating. While some manufactures will apply added flavors to unwaxed nylon floss, most choose to sell it plain.
Waxed dental floss has a special waxy coating applied to the strand. The waxy coating helps the strand slip into tight places, making it preferable for people with tight-fitting teeth or braces. The wax can also be treated with flavor additives like mint or cinnamon.
Clinically speaking, both variations of floss are equally effective at removing residual food particles and plaque from between teeth and the gumline. It is ultimately a matter of personal preference.
If you have questions about dental floss in Coos Bay, Oregon, or how to improve your flossing technique, you can always call 541-269-5353 to speak with someone at South Coast Family Dentistry.


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There is a new show on Bravo called My Fab 40th, and all I can say is, some clever intern must have pulled a fast one while all the network executives were in the Hamptons. Or a rogue producer has the goods on someone in the C-suite. Either way, something is amiss here.
We all know Bravo as the home of the Housewives (though, for the most part, there is nary an extant marriage in sight). This juggernaut franchise ensures that on any given night those of us with work-a-day lives can tune in to watch women with too much money drink their faces off, cat fight on yachts, and promote their mythical "lifestyle" brands.
Our parents had Walter Cronkite. So, you know, tomato, to-mah-to.
But while no one apparently was minding the store, in walked Brandy Flores, the featured 39.9 year old subject of a show marketed as the mid-life answer to MTV's My Super Sweet 16. The concept is simple: a woman, her friends, and a few assorted professionals throw the subject a lavish 40th birthday party.
I hadn't intended to linger too long, as the teaser on my cable guide described this week's plot: Brandy, an amateur race car driver and fitness model, hopes her boyfriend will propose at her 40th birthday party, which her friend Bethany is throwing at the racetrack. From that description, my Venn diagram of commonality with Brandy appeared to be that we both like celebrating our birthdays. In fact, had HGTV been running anything but Flip or Flop (I'm sorry, that couple just puts no love into their renovations), I would have missed the whole thing.
I'm glad I didn't.
Brandy is divorced. She has two sweet daughters, who are featured only in a few scenes, but who seem like nice kids who love their mom. In the cutaway scenes, Brandy talks about how hard it is that they have to split time between her home and her ex-husband's, and how she tries to find ways to make their time together special.
Brandy has a good cadre of girlfriends, who all seem invested in her happiness. If I were to bend Brandy's ear, I might suggest keeping the one who spilled wine on her head at happy hour at a bit of an arms' length. But the only apparent beef between these women is the barbecue they're happily chowing at a restaurant called "Smoqued" as they try to help Brandy figure out her future.
This may be implicit in the term "fitness model," but Brandy is also a knockout. Her arm definition is exquisite. She has a killer smile and clearly follows a sound skin regimen. Did I mention she's a fitness model? Right, so about that: one scene features her enduring a grueling workout of lunges while she's holding what looks like cement blocks in each hand. Then she sits on a mat and talks about how much harder it is to book the modeling gigs at her age, and the stress she feels at needing to work twice as hard as she used to so she can support herself and her children.
That's when it hits me.
God help me, I like this Brandy. I would totally ham it up in the photo booth at Brandy's Fab 40th.
Then there is Jim, the boyfriend of six years. What Brandy wants most at her racetrack chic 40th bash is for Jim to propose. She has sent him a picture of the ring she wants – a fairly silly move with great backfire potential – but she also sits down with him over dinner in their very average looking kitchen and tells him that being in limbo at 40 isn't going to work for her. Jim looks uncomfortable, attempts some revisionist Jedi mind trick about how he always told her he never wanted to marry again, and retires to his study where he has been shopping online for a race car to present to Brandy at the party. In another scene, Brandy's friend gets wind of the race car plan and tells Jim point blank that if he doesn't buy Brandy a ring, she's going to be crushed.
Cut to commercial.
At this point, I am certain that I've doped out the remaining scenes. Jim messes with Brandy's head a bit, but in the end, he's on one knee as the candles on her towering purple cake are lit. He's brought her daughters along as a surprise, because the moment is too important for them to miss. After all, Jim doesn't seem like a total jerk, and the fool who would give up Brandy is only second in line to the fool who would make a show in which an $80,000 birthday party for a woman the viewers have come to root for ends with Jim disappointing Brandy in front of all her friends.
And yet, that's exactly what happens. Brandy's friends go all out. The party is in full swing, and she looks amazing in a silver sequined dress. There's an ice sculpture and lounge seating. She is serenaded by her favorite country singer. Out of nowhere, there's Lorenzo Lamas, who as far as I know hasn't been seen since Falcon Crest, and he presents her with a cool racing suit. Brandy is radiant, toasting her dear friends who have seen her through phases of life that she didn't plan for and that have brought their share of struggle. Then Jim brings every single guest outside to the track, gives a speech in which he says "Brandy has waited a long time for this," and pulls a tarp off a race car. It is wrenching to watch Brandy feign excitement, then get into the car and look around the front seat in the forlorn hope that the ring is there.
I brace for the explosive confrontation. At least fifty of Brandy's friends have been swilling theme cocktails for hours and have warned Jim in no uncertain terms that he'd better do right by their girl. Jim's best hope is that the massive party budget included staffing for a medical tent.
Cut to commercial.
We never see Jim again.
It's a sunny morning, the day after the party. Brandy doesn't look puffed up from crying, or particularly despondent. She arrives at Bethany's house to thank her for all the hard work and planning. We learn that Brandy left the party with one of her pals, Lindsey; they went for late night sushi and did sake toasts to the beginning of her fifth decade. No big scene, just great resolve. Our Brandy walked off that racetrack and left Jim in the deafening roar of his own dick move.
Bravo's motto is "Watch What Happens." Having watched what happened as Brandy turned 40, I got perhaps the greatest shock from this purveyor of all things shock value: a show about a woman who hoped things would turn out differently, but when they didn't, had to make a hard choice about what was best for herself and her daughters. Her friends stood by her. No one lied to her or gave her false hope that Jim was going to see the light. In the final scene, Brandy and her daughters light candles on a simple plate of cupcakes in Bethany's kitchen. Somewhere last night's ice sculpture is melting into oblivion. But this little party beats that one any day. Brandy's 40th never looked so fab.
As for the race car? I hope Brandy sells it and upgrades to a better model that she chooses for herself. Or maybe she sells it and takes her friends and daughters on a beach vacation. Or maybe she just drives it as fast as her heart desires. It doesn't really matter, in the end, because she's already made wise use of its most important part: the rear view mirror.
Happy birthday, Brandy. I don't have to tell you, but you've got everything you need, right there in Bethany's kitchen.
So I will just say this: Bravo.


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On a nice weekend the garbage really piles up. There are THREE styro-coolers in this garbage can.
Lost tank top.
Some ledge graffitti. What the Heck does D30 mean?
Human bloodstain. The new book by Phillip Roth.
Lame Star Wars Joke Here.
Abandoned mandals.
A few pieces of garbage get between the heavy metal container and the light plastic can. No one wants to either lift the heavy metal thing or reach into it to pick out the filthy garbage. So eventually the can gets higher and higher. A rising trash lifts all boats.
Either a love note or a command.
This "Monster" truck was handing out free Monster energy drinks. Mmmmm... delicious taurine.
Now what does this graffitti mean? Maybe it's a warning that up ahead...
Wednesday, July 18, 2007
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Extended Committee
Introduction to TACT
Annamaria de Luca, as TACT chair, is leading this exciting initiative with the support of the TACT core, nominated committee members and the TREAT-NMD secretariat. TREAT-NMD is confident that the breadth and calibre of the international TACT experts will ensure the quality of the output.
The aim of TACT is to provide transparent and consistent guidance and advice to the neuromuscular community, and applicants, in an educational and directional context, on the readiness of drugs and/or therapeutic targets for trials in neuromuscular diseases.
The remit of the committee is to evaluate the therapeutic potential of drugs based on preclinical data, thereby assisting TREAT-NMD in identifying clinical trials to be run via the network. TACT advice will be helpful for preparing funding applications and investigational drug applications, and serve as an unbiased appraisal to be published for the wider neuromuscular community. We hope that this process would be endorsed by the major funders.
In addition to the expert analysis of preclinical data TACT will also address issues of drug formulation, bioavailability and toxicology as well as possible regulatory requirements and marketing considerations. In close collaboration with the TREAT-NMD clinical trials coordination centre in Freiburg TACT is also dedicated to providing information on rational and economical trial design. The ultimate goal of TACT is to help pave the pathway for successful drug registration by providing professional and independent advice.
The TACT appraisal process of potential therapeutics for clinical trials will take a maximum of 6 months. TACT will consider more than one drug at a time and therefore will have panels of experts, selected from the TACT members, reviewing the drugs concurrently, with the same chair and core committee for continuity.
Annemieke Aartsma-Rus - Preclinical expert
Professor - Leiden University Medical Center
Dr. Annemieke Aartsma-Rus is a professor of translational genetics at the Department of Human Genetics of the Leiden University Medical Center and leader of the DMD genetic therapy group. She was previously Chair of the executive committee of the TREAT-NMD alliance, president-elect of the Oligonucleotide Therapeutics Society and is a member of the Project Ethics Council and TACT Committee.
Hugh Allen - Clinical Representative
Professor of pediatrics and medicine - Texas Childrens Hospital
Hugh's background is in echocardiography and cardiac function analysis, coupled with a large experience with the muscular dystrophy population. Presently he is a Professor of Paediatrics at Baylor College of Medicine, and is Staff Cardiologist at The Heart Center at Texas Children's Hospital where he directs the care of neuromuscular cardiology patients.
More Info
Call +1 8328265600
Dimitrios Athanasiou - Patient Advocate
DMD Patient Advocate, UPPMD Board Member, EMA Patient Expert in DMD - Texas Childrens Hospital
Dimitrios Athanasiou holds a BA in Business Administration and an MBA in Financial Management. He speaks three European languages and has more than 25 years' experience with international business projects, working in various countries in consulting, developing and reorganizing companies.
When his son was diagnosed with Duchenne Muscular Dystrophy, a fatal and incurable rare disease, he become a strong international patient advocate in Duchenne and Rare Diseases.
Having a passionate personality and technocratic background, he educated himself with basic rare disease and advocacy knowledge via the EURORDIS Summer School and then with the 14 month Patient Expert Course of the European Patient Academy of Therapeutic Innovation (EUPATI) acquiring basic biotech and regulatory knowledge, where he served as a Member of EUPATI's Course Committee for the next year, representing the patient voice. Being a EUPATI fellow, he established the Greek EUPATI National Liaison Team.
More Info
Call +30 (0) 6944604292
Fabiola Bertinotti
Vice-president of FSHD Europe - Texas Childrens Hospital
Since Fabiola's adopted son was diagnosed with Facioscapulohumeral Muscular Dystrophy in 2005, Fabiola became deeply involved in the world of neuromuscular diseases. In Italy, Fabiola has been an active member of patient's association Unione Lotta alle Distrofia Muscolare (UILDM), and has recently joined Coordinamento Associazioni Neuromusculari (CAMN).
At an international level, Fabiola is one of the founding members of FSHD EUROPE, a federation of local FSHD and other Muscular Dystrophy organizations whose main objective is to represent the interests of these European organizations in relation to their various international stakeholders. After serving for three years as president, during which the association expanded its reach to include various European FSHD and other Muscular Dystrophy local associations, Fabiola has been appointed Vice-president with specific focus on patient's interests and TREAT-NMD. Fabiola is passionate about open science and co-creation and has enrolled into the EURORDIS Summer School program.
John Bourke - Clinical Representative
Consultant Cardiologist - Freeman Hospital
John graduated from the University College Dublin, Ireland in 1979. He is currently a Consultant Cardiologist (Electrophysiologist) at the Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK, Senior Lecture at Newcastle University & an Associate Member of Institute of Human Genetics, International Centre for Life, Newcastle.
Arthur Burghes - Preclinical Expert
Professor - Ohio State University College of Medicine
Arthur completed his BS in Cellular & Microbial Biology in 1978 at the University of Calgary and his PhD in Biochemistry at University of London.
Gunnar Buyse - Preclinical Expert
Professor of Pediatrics & Pediatric Neurology - Universite Catholique de Louvain
Gunnar Buyse (MD, PhD) is Professor of Pediatrics and Child Neurology at the University of Leuven (Katholieke Universiteit Leuven), and is deputy clinical chair of Child Neurology at the University Hospitals Leuven. Gunnar Buyse is a Committee Member of the TREAT-NMD Advisory Committee for Therapeutics (TACT).
More Info
Call +32 16 34 38 45
Donald Cairns - Medical Chemistry
Head of the School of Pharmacy and Life Sciences (PALS) - Robert Gordon University
Professor Donald Cairns obtained his Pharmacy degree and PhD from the University of Strathclyde. Following a year as a post-doctoral research fellow with the Cancer Research Campaign, Donald moved to Leicester Polytechnic where he held a five-year lectureship in pharmacy. In 1992 Donald was appointed senior lecturer in medicinal chemistry in Sunderland School of Pharmacy and in 2003 moved to Robert Gordon University in Aberdeen as Associate Head. In 2006, he was promoted to Professor of Pharmaceutical and Medicinal Chemistry, in 2010 he was appointed Acting Head of School and in 2012 he was appointed to his present post of Head of the School of Pharmacy and Life Sciences.
Paula Clemens - Clinical Representative
Professor of Neurology - University of Pittsburgh
Paula has a career-long interest in the muscular dystrophies spanning clinical care, basic research and clinical research endeavors. She is experienced as a site PI and study chair for studies conducted by the multi-center clinical trial network comprised of more than 25 centers worldwide, the Cooperative International Neuromuscular Research Group (CINRG).
Giulio Cossu - Clinical expert and cell therapy
Constance Thornley Professor of Regenerative Medicine - University of Pittsburgh
Giulio Cossu is Constance Thornley Professor of Regenerative Medicine at the University of Manchester. He received his MD degree from the University of Rome, then moved as Fogarty fellow at the University of Pennsylvania and in 1992 became Professor of Histology and Embryology in Rome. In 2000 he became Director of the Division of Regenerative Medicine at San Raffaele in Milan. In 2012 he moved as Professor of Human Stem Cell Biology to University College London and in 2013 to the University of Manchester.
He has been working as CAT member at EMA (2012-13). He is EMBO Member, Member of the European Academy of Science, Fellow of the Academy of Medical Sciences and of the Accademia dei Lincei. Giulio Cossu is recognized for his pioneering work on muscle development and on cell therapy for muscular dystrophies. He has published more than 200 peer-reviewed papers and secured grants for more than 10 M£.
Giulio Cossu has no conflict of interest to disclose.
More Info
Call +44 (0)16130622526
Cristina Csimma - Drug development expert
Principal - Csimma LLC
Cristina Csimma's experience in the biopharmaceutical, venture capital and academic settings encompasses global development in multiple therapeutic areas including rare neuromuscular diseases, translational through registration clinical studies, and integration of biomarkers and novel technologies into development as well as leadership roles in new company formation and fund raising. Dr Csimma served several years on the Core Committee and has reviewed many of our applications.
Simon Day - Regulatory and Statistical Expert
Independent consultant - based in the UK
Simon is a medical statistician with around 30 years' experience working in clinical trials. He has worked in many different therapeutic areas and has been involved in academic-run studies as well as many carried out by the pharmaceutical industry. Apart from trial expertise, he also has a lot of experience in the overall drug-development process.
Beatrice de Montleau - Patient Organisation Representative
Board of Directors - Association Française contre les Myopathies - AFM
Beatrice de Montleau is the mother of three children, the youngest of whom is affected by Duchenne Muscular Dystrophy. Beatrice began her volunteer involvement with the AFM (French Muscular Dystrophy Association) by serving on the financial committee, bringing to that service a professional background in internal audit and sustainable development.
Marianne de Visser - Clinical Representative
Neurologist, Professor of Neuromuscular Disorders - Amsterdam Medical Centre
Marianne has been the leader of the neuromuscular group at the Academic Medical Centre in Amsterdam in the Netherlands for more than 20 years. During this time her group has contributed to research on muscular dystrophies, myositis, motor neuron diseases and hereditary neuropathies.
More Info
Call +31-20-5663445
Sven Dittrich - Clinical Representative
Head of the Department of Pediatric Cardiology - Children's Hospital, University Hospital Erlangen
Prof. Sven Dittrich, MD is principal investigator of the German multicentric trial "Effect and Safety of preventive Treatment with ACE-Inhibitor and Beat-Blocker on the onset of Left Ventricular Dysfunction in Duchenne Muscular Dystrophy", which is organized within the MD-Net and the German Competence Network for Congenital Heart Disease. His group also works on Tissue Doppler and cardiac MRI in Duchenne patients.
Alberto Dubrovsky - Clinical Representative
Director of Dept of Neurology and Director Neuromuscular Unit - Fundacion Favaloro Hospital Universitario
Alberto Dubrovsky, MD, is currently Director of the Department of Neurology, Director of Neuromuscular Disease Unit of the Neurosciences at Fundacion Favaloro. Since 1983 he has also served as Medical Director of the Argentina Muscular Dystrophy Association. Alberto is a Professor of Neurology at the University of Buenos and a Full Professor of Neurosciences at the Favaloro University, training as a Neurologist in the field of Neuromuscular Diseases at NIH under the sponsorship of W King Engel.
More Info
Call +54 11 490 40635
Gustavo Dziewczapolski
Scientific Director, Cure CMD - Fundacion Favaloro Hospital Universitario
Dr. Dziewczapolski is the Scientific Director of Cure CMD. He plays the role of liaison between researchers, clinicians, pharma industry, patients and families with the aim of accelerating CMD research, diagnostics, care standards, and translation of research discoveries into real therapies.
Michelle Eagle - Physical Therapist Representative
Consultant Physiotherapist - Newcastle University
Michelle initially specialised in Rheumatology and gained a masters degree in the clinical evaluation and development of outcome measures in Ankylosing Spondylitis.
Kenneth Fischbeck - Preclinical Expert
Branch Chief - National Institute of Neurological Disorders and Stroke
Kurt is an NIH Distinguished Investigator and Chief of the Neurogenetics Branch at NINDS and a TREAT-NMD STAC member. He has experience with preclinical (animal) studies in various neuromuscular diseases including Duchenne muscular dystrophy, spinal muscular atrophy, and spinal and bulbar muscular atrophy (SBMA), and he has run clinical trials and biomarker studies in Duchenne muscular dystrophy, spinal muscular atrophy, Friedreich's ataxia, and SBMA.
More Info
Call 1-301-435-9318
Kevin Flanigan - Clinical Representative
Professor of Pediatrics and Neurology - Ohio State University College of Medicine
Kevin is the Director of the United Dystrophinopathy Project, an NIH-funded consortium studying the natural history and genotype/phenotype correlations in the DMD gene.
Pat Furlong - Patient Organisation Representative
CEO - Parent Project Muscular Dystrophy
Pat Furlong is the Founding President and CEO of Parent Project Muscular Dystrophy (PPMD) which she founded together with other parents of young men with Duchenne in 1994.
Nathalie Goemans - Clinical Representative
M.D - UZ Leuven
Dr Nathalie Goemans (M.D. PhD) is a paediatrician and child neurologist, with certification in rehabilitation medicine and is currently head of the Neuromuscular Reference Centre within the department of Paediatrics and Child Neurology at the University Hospitals Leuven, Belgium, and consultant in neuropediatrics at DVC St Jozef Antwerp, Belgium, a rehabilitation centre with residential setting for neuromuscular patients.
More Info
Call +32 16 34 38 45
Heather Gordish-Dressman
Associate Professor of Pediatrics - UZ Leuven
Dr. Gordish-Dressman is an Assistant Professor of Pediatrics at George Washington University School of Medicine and Health Sciences and the Center for Translational at Children's National Health System and is a statistician focusing on in neuromuscular diseases.
Amelie Gubitz - Pre-clinical representative
Program Director at the National Institute of Neurological Disorders and Stroke - UZ Leuven
Amelie Gubitz serves as a Program Director at the National Institute of Neurological Disorders and Stroke (NINDS), USA. Her portfolio includes basic, translational and clinical research on amyotrophic lateral sclerosis, X-linked spinal and bulbar muscular atrophy, Friedreich's ataxia and hereditary spastic paraplegia. Amelie earned a Ph.D. in pharmacology from the University of Cambridge, UK, and then completed a Wellcome Trust Fellowship at Harvard Medical School. Subsequently, she worked as a Senior Scientist in the target discovery group for neuropathic pain at Parke Davis, UK. Prior to joining the NINDS in 2006, she studied the molecular pathogenesis of spinal muscular atrophy in the laboratory of Dr. Gideon Dreyfuss at the University of Pennsylvania.
Elin Haf Davies - Regulatory and clinical trial data expert
CEO, Aparito - UZ Leuven
Elin Haf Davies PhD is the CEO of Aparito, a company developed to support the adoption of technology and innovative solutions for monitoring patients in clinical trials and introducing innovative study designs, and data generation strategies. Prior to Aparito, Elin Haf has 18+ years of clinical, academic and regulatory drug development experience.
Jon Hastie - DMD Patient Representative
CEO, DMD Pathfinders - UZ Leuven
Dr Jon Hastie is the CEO of DMD Pathfinders, a user-led organisation of adults with Duchenne. He co-founded DMD Pathfinders in 2014 after working for several years on a transition programme for young people with Duchenne and has been a co-researcher on key social studies of adults with DMD. As an adult with Duchenne himself he has a detailed knowledge of the condition and its physical, social and psychological impacts in adulthood.
Eric Hoffman - Drug development
Director, Research Center for Genetic Medicine & The Wicker Project for Muscular Dystrophy Research - CINRG
Eric Hoffman, is Associate Dean for Research, School of Pharmaceutical Sciences, Binghamton University - SUNY, New York, USA and the CEO of ReveraGen BioPharma, Rockville, MD USA
Joseph Irwin - Ethical Input
Consultant - Lakeside Regulatory Consulting Services Ltd
Joseph Irwin became a Member of Spinal Muscular Atrophy Support UK (previously The Jennifer Trust for Spinal Muscular Atrophy) after his first son Toby was diagnosed with Type I SMA. Joseph, who is a biochemist-pharmacologist with molecular biology and cell biology experience, has worked for many years in hospital based research and for the pharmaceutical industry.
Jill Jarecki - Preclinical Expert
Research Director - Cure SMA
Jill is the Chief Scientific Officer at Cure SMA (formerly Families of SMA), and she has worked there since 2005. In this capacity, she has overseen over 40 million in SMA research investments, including in basic research, preclinical drug development, clinical research, and regulatory work.
Hermien Kan
Associate Professor - Leiden University Medical Center
Dr. Hermien E. Kan is staff member of the C.J. Gorter Center for high field MRI at the Leiden Universtiy Medical Center, where her main focus is on quantitiatve MR muscle and brain in Duchenne and Becker muscular dystrophy and high field muscle MR spectroscopy.
More Info
Call + 31 71 5265608
Petra Kaufmann - Clinical Representative
Director, Division of Clinical Innovation - NCATS
Petra Kaufmann, M.D., M.Sc., is Director of the Division of Clinical Innovation at the National Center for Advancing Translational Science (NCATS). In this capacity, she oversees the Clinical And Translational Science Award (CTSA) program, which supports a national consortium of medical research institutions working to transform the way biomedical research is conducted.
More Info
Call +1 301 435 0178
Oliver King - Statistician
Assistant Professor - University of Massachusetts Medical School
Dr Oliver King is an assistant professor in the Department of Neurology at the University of Massachusetts Medical School
Donald Kirsch - Research and Development / Drug Discovery Expert
Research and Development / Drug Discovery
Dr Donald Kirsch has almost 35 years of R&D leadership and management experience in the biopharmaceutical industry. He currently runs a biopharma consulting practice in Boston and New York, teaches Drug Discovery and Management at the Harvard University Extension School and courses at MassBio.
Rudolf Korinthenberg - Clinical Trial Coordination centre representative
Director, Neuropediatrics and Muscular Disorders - University Medical Center Freiburg
Prof. Rudolf Korinthenberg, MD is head of the Department of Neuropediatrics and Muscular Disorders at Children's Hospital, University Hospital Freiburg. He received his pediatric and neuropediatric training at University Hospital Münster/Westfalia and holds his actual position since 1990.
More Info
Call +49 761 270 43150
Richard Lovering - Physical Therapist Representative
Associate Professor, Orthopaedics - University of Maryland - School of Medicine
Rich worked as a physical therapist starting in 1886. He returned to school and received his PhD in 2003, which was aimed at elucidating the cellular and molecular changes that occur during eccentric injury to muscle. He performed his post-doctoral work in the Department of Physiology at the University of Maryland (UMB) School of Medicine where he examined the role of intermediate filaments in skeletal muscle. There are many parallels in muscle that is injured, aging, or dystrophic; thus these are foci of work in the Lovering Laboratory. The Lab still maintains a strong interest in measuring muscle function (in vivo contractility) and relating the outcomes to changes at the cell level and to changes seen using non-invasive MR imaging and spectroscopy. The most recent efforts have been focused on elucidating the role of nuclear mobility, position, and function in dystrophic and aging muscles, and relating these findings to overall muscle function.
Linda Lowes - Physiotherapist
Director of Clinical Therapies Research - Nationwide Children's Hospital
Linda Lowes, PT, PhD is the director of clinical therapies research and a member of the Center for Gene Therapy at the Research Institute of Nationwide Children's Hospital.
Oscar Henry Mayer - Clinical Representative
Medical Director, Pulmonary Function Testing Laboratory - Children's Hospital of Philadelphia
Dr. Oscar Henry Mayer is an Associate Professor of Clinical Pediatrics at The Perelman School of Medicine at the University of Pennsylvania, and an Attending Pulmonologist within the Division of Pulmonology at the Children's Hospital of Philadelphia (CHOP), where he is the medical director of the CHOP Pulmonary Function Testing (PFT) laboratory.
Anna Mayhew - Physical Therapist Representative
Consultant Research Physiotherapist - Newcastle University
Dr Anna Mayhew is a Consultant Research Physiotherapist at The MRC Centre for Neuromuscular Diseases at Newcastle, Newcastle University.
John McCall - Toxicology Expert
President, PharMac LLC - PharMac LLC
John McCall's expertise is drug discovery, risk minimization, and medicinal chemistry. He has worked in a number of disease areas including acute and chronic neurologic disorders, psychiatric diseases, neuromuscular disease, cardiovascular disease, inflammatory disease, and oncology. He is currently President, PharMac LLC. Dr McCall has served for several years on our Core Committee and has reviewed many of our applications.
More Info
Call +1 941 2686393
D. Elizabeth McNeil - Regulatory Expert
National Institutes of Health - NIH
Dr. Elizabeth McNeil came to NINDS in 2010, after working for 8 years at the US Food and Drug Administration (FDA). While at the FDA, she worked extensively on a full range of products, including new molecular entities, new formulations of approved drug products, drug-drug combinations, and drug-device combinations. She worked to develop new scientific, clinical and regulatory standards for the development of certain drug classes and developed initiatives which resulted in standardization and clarification of terminology used in defining claims and endpoints, as well as in increased standardization, precision, and sensitivity in reporting safety and efficacy data.
More Info
Call +1 301 402 1660
Debra Miller
Founder and CEO - CureDuchenne
Debra Miller co-founded CureDuchenne in 2003 with her husband, Paul, after their only son was diagnosed with Duchenne. She relies on her extensive background in sales and marketing to lead CureDuchenne.
Jenny Morgan - Pre-clinical and stem cell expert
Professor - CureDuchenne
Jennifer Morgan is a Great Ormond Street Hospital Children's Charity Professor of Cell Biology in the Dubowitz Neuromuscular Centre, Molecular Neurosciences Section, Developmental Neurosciences Programme, University College London Great Ormond Street Institute of Child Health. She is a member of the muscular dystrophy exon skipping (MDEX) consortium where she is involved in the analysis of dystrophin exon skipping and dystrophin protein production in cells and muscles of patients treated with antisense oligonucleotides in clinical trials. She is also a PI of the MRC Centre for Neuromuscular Diseases, a partnership between the UCL Institutes of Neurology and Child Health and the University of Newcastle upon Tyne, directed by Professor Michael Hanna at the UCL Institute of Neurology.
Wolfgang Müller-Felber
Associate Professor of neurology, Neurologist and psychiatrist, pediatric neurologist - CureDuchenne
Wolfgang Müller-Felber is a pediatric neurologist at the Dr. v. Hauner children's hospital at the university of Munich (LMU), Germany. He has a longstanding interest in neuromuscular disorders.
Francesco Muntoni - Clinical Representative
Director of The Dubowitz Neuromuscular Centre - University College London
Francesco Muntoni (Professor in Pediatric Neurology, FRCPCH, FMedSci) is Director of the Unit with oversight of both clinical and research activities.
Kanneboyina Nagaraju (Raju) - Preclinical Expert
Professor of Integrative Systems Biology and Pediatrics - Childrens National Health System
Kanneboyina Nagaraju, DVM, PhD is a principal investigator at the Research Center for Genetic Medicine, Children's National Medical Center (CNMC) and a tenured associate professor of Integrative Systems Biology and Pediatrics at George Washington University School of Medicine and Health Sciences.
Ichizo Nishino
Director, Department of Neuromuscular Research - National Institute of Neuroscience - National Center of Neurology and Psychiatry
After having 5 years of clinical neurology training, Dr. Nishino started muscle disease research from 1994 under the tutelage of Dr. Ikuya Nonaka, who remained a steadfast source of inspiration. Later, his postdoctoral research for two years at Columbia University solidified his yearning to focus on research. In 2001, he was appointed directorship of the current Department of Neuromuscular Research and since then, he has been directing his team on the research to elucidate the pathomechanism and develop the therapy for hereditary muscle diseases, including DMRV/hIBM and various muscular dystrophies.
Marie-Christine Ouillade - Patient Organisation Representative
President of SMA Europe - Association Française contre les Myopathies - AFM
Marie-Christine is the mother of a young lady affected by SMA. She is president of SMA Europe an umbrella association of SMA patients organization in Europe She is also a member of AFM Board of Directors, and GENETHON board of directors.
Mike Pleiss - Pharmacology Expert
Pharmaceutical Research and Development Executive - Mike Pleiss and Associates, LLC
Mike was part of several project teams (and head of the multiple sclerosis (MS) / autoimmune effort) that resulted in several first-in-class therapeutics for Alzheimer's (AD), MS and other autoimmune diseases.
John Porter - Preclinical expert and patient advocacy
Chief Science Officer, Myotonic Dystrophy Foundation - Mike Pleiss and Associates, LLC
John Porter, Ph.D. is Chief Science officer for the Myotonic Dystrophy Foundation, a non-profit focused on improving patient care and developing novel therapies for myotonic dystrophy. He has a strong interest in ensuring the scientific rigor of preclinical study design, conduct, and the validity of data used to provide rationale for clinical trials, across all neuromuscular disorders, and played a key role in efforts to include such considerations in Federal and non-Federal grant review processes.
Christoph Rehmann-Sutter - Ethical Input
Professor of Theory and Ethics in the Biosciences - University of Lübeck
Christoph Rehmann-Sutter is a philosopher, Professor of Theory and Ethics in the Biosciences at the University of Lübeck in Germany and currently also Visiting Professor at King's College in London. Born in 1959 he obtained a first training in molecular biology with a Diploma from the Biocenter at University of Basel in 1984, then a second full training in philosophy and sociology with a doctoral degree at the Technical University of Darmstadt 1995. 1997-1998 he joined the Department of Environmental Science, Policy and Management ESPM of the University of California at Berkeley as a Research Fellow. 1996-2009 he was Head of the Unit for Ethics in the Biosciences at the University of Basel in Switzerland. 2001-2009 he was Chair of the Swiss National Advisory Commission on Biomedical Ethics, elected by the Swiss Government, advising parliament and government.
Isabelle Richard
Since her PhD studies in 1991, Isabelle has been working on Limb Girdle Muscular Dystrophies: identification of the genes and study of their protein functions to identify pharmacological solutions, development of animal models and investigation of gene transfer by gene therapy.
Urs Ruegg - Pharmacology Expert
Professor emeritus of Pharmacology - University of Geneva
After twelve years of drug research in the Basel pharmaceutical industry, Urs joined the University of Lausanne as Professor of Pharmacology in 1992. Since 2004 he has headed the Laboratory of Pharmacology at Geneva – Lausanne School of Pharmaceutical Sciences, University of Geneva. Since 1992, he has had full responsibility for the entire curriculum in pharmacology for pharmacy students.
Monique Ryan - Clinical Representative
Director, Neurology Department, The Royal Children's Hospital, Melbourne - The Royal Children's Hospital
Monique is a paediatric neurologist with a long interest into clinical research into the neuromuscular disorders of childhood. She has expertise in the design and performance of clinical trials - both into natural history and of pharmacotherapeutic agents - in muscle and nerve disorders of childhood, as well as a research interest into outcome measures (particularly neurophysiologic and functional measures). She is Director of the Neurology Department at The Royal Children's Hospital in Melbourne.
More Info
Call +61 39345 5661
Lars Sandman - Ethics
Professor of Care Ethics - University of Boras
Professor Lars Sandman is a philosopher by training and received his PhD in practical philosophy from Gothenburg university in 2002. He is currently professor of care ethics at University of Borås, Sweden, and guest professor at the National Centre for Priority Setting in Health Care at Linköping University, Sweden.
Jeremy Shefner - Clinical Representative
Professor and Chair of Neurology - Upstate University Hospital
Jeremy Shefner, MD, PhD, is Chair of the Department of Neurology and Associate Director for Barrow Neurological Institute.
Lee Sweeney - Preclinical Expert
Professor and Chair of the Department of Physiology at Perelman School of Medicine of the University of Pennsylvania - Upstate University Hospital
H. Lee Sweeney, Ph.D., is the William Maul Measey Professor and Chair of the Department of Physiology at Perelman School of Medicine of the University of Pennsylvania. He is working to develop therapies for the skeletal and cardiac muscle aspects of muscular dystrophies using both small molecule and gene therapy approaches. Dr. Sweeney is the Director of a Wellstone Muscular Dystrophy Cooperative Research Center funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
Ulrike Schara - Clinical Representative
MD - University of Essen
Ulrike Schara is a paediatric neurologist at the university hospital in Essen, Germany. She has a long-standing clinical interest in muscle disorders and CMS. She has recently started to build a patient registry for CMS in collaboration with TREAT-NMD.
Jeff Towbin - Clinical Representative
Professor and Chief, Pediatric Cardiology, Executive Co-Director The Heart Institute - Cincinnati Children's Hospital
Dr. Jeffrey A. Towbin, Executive Director of the Heart Institute and Professor & Chief, Pediatric Cardiology at Le Bonheur Children's Hospital, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center in Memphis, did his Pediatric Residency at Children's Hospital Medical Center in Cincinnati.
Jan Verschuuren - Clinical Representative
Head of Neuromuscular Section, Department of Neurology - Leiden University Medical Center
Jan Verschuuren is a neurologist and professor of Neuromuscular Disease at the LUMC. He is the clinical representative for the LUMC in TREAT-NMD, and president of the Dutch Neuromuscular Centre (www.ISNO.nl).
More Info
Call +31 71 5262197
Maryze Schoneveld van de Linde - Patient expert - Pompe disease
Leiden University Medical Center
On February 1, 2009 Maryze Schoneveld van der Linde joined the ENMC as project manager for TREAT-NMD. In 1995 Maryze Schoneveld van der Linde graduated with a masters degree in Cultural Anthropology at the University of Leiden. Since 1996 she has been working with migrant and refugee women from Turkey and the Middle East Region in empowerment related issues and activities.
Maryze Schoneveld van der Linde has been an active board member of the Dutch Association for Respiratory Support (VSCA, 1997 - 2006) and an active board member of the International Pompe Association (IPA, 1999 - 2006).
Currently she is advisor of the IPA. In 2007 she started a consultancy in health and care called Patient Centered Solutions. With her consultancy she provides clients with experienced based expertise, knowledge and practical insights from a patient's perspective regarding issues related to health and care.
Elizabeth Vroom - Patient Organisation Representative
Chair, World Duchenne Organisation (UPPMD) - Leiden University Medical Center
Elizabeth is the president of Dutch Duchenne Parent Project and the chair of United Parent Projects Muscular Dystrophy (UPPMD). UPPMD is owned and managed by parent project organisations set up by parents of children with Duchenne Muscular Dystrophy in many different countries all over the world. As the chair of UPPMD, Elizabeth can represent the Duchenne parent community on the TACT committee.
Maggie Walter - Clinical Representative
Associate Professor of Neurology - Friedrich-Baur Institut, Ludwig-Maximilians University Munich
Maggie Walter is Associate Professor of Neurology at the Ludwig-Maximilians-University of Munich. She has trained as a neurologist at the LMU Munich, and is working at the Friedrich-Baur-Institute, the neuromuscular department of the LMU, in leading position. Furthermore, she graduated with a master degree in management of social and health institutions.
Dominic Wells - Preclinical Expert
Professor Neuromuscular Diseases Group - The Royal Veterinary College
After several years in general practice he moved to the USA and did his PhD on hummingbird flight. After that he returned to the UK with a lecturer post at the Royal Veterinary College where he first became involved in DMD research. From 1995 he has been based at the Imperial College.
Raffaella Willmann
TREAT-NMD activity coordinator - Swiss Foundation for Research on Muscle Diseases
Raffaella Willmann studied Biology in Italy and obtained her PhD in Biochemistry in Konstanz (Germany). After a first post-doc position in muscle physiology in Konstanz, she joined the group of Prof. Fuhrer in at the University of Zürich in 2000.
Since 2012, she is affiliated to the Swiss Foundation for Research on Muscle Diseases as scientific assistant.
Meg Winberg - Preclinical Expert
Independent consultant - based in the USA
In Meg's former capacity as Director, Discovery Research at the Spinal Muscular Atrophy Foundation she has driven and overseen the Foundation's efforts in the development and execution of new cell-based assays and drug screens and implementation of standardized drug testing in a mouse model of SMA.
Minal Jain
Research Coordinator - based in the USA
Minal Jain, PT, DSc, PCS is the research coordinator for the physical therapy section of the Rehabilitation Medicine Department at the NIH Clinical Center.


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Whether you need to replace all of the drywall in your home or just fix a few blemishes, our team at Ceilings Etc. always recommends to work with a professional. Not sure what to expect with this type of service? We've made a list to help you understand more about how drywall contractors help.
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There is absolutely no abate to the hot weather in this part of the country. While other parts are gradually starting to cool, Durban on the other hand is still experiencing high temperatures. And the only way to make it through a 30 degree day, presentably and stylishly, is by adorning yourself in the right, light fabrics. This is what becoes part of every gent's sartorial journey, an interminable lesson in fabrics and materials. The only way I survived was through cotton and linen. I also experimented with the same pattern, pin-stripes.
This navy blue pin striped jacket is 100% linen, and like I have stated before, it's very sturdy and doesn't wrinkle easily. I also like the fact that it is not a too wide or narrow peak lapel, it's balanced just right, that's why I was not averse to mixing in this turquoise cotton knit tie. I used a light pink cotton shirt as a canvass upon which to play around with colours. That's why I also decided to go with this bright pink paisley pocket square. For a size 42R the jacket still fits perfectly and I' quite impressed with the fit around the shoulders. It's got a slightly raised sleeve head which gives it a structured look and feel.
The trousers are a cotton-wool blend, and against the lightness of the jacket, I think they hold up well. They have a mixture of stripes in different colours and this allowed e to play around with a range of colours. The scale in stripes also doesn't become a challenge because this small stripes upon small stripes. There might be a difference in the colours of the two most prominent garments, however, the stripes ensure a continuation and congruence from head to toe.


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Clearance Sticks » Clearance Sticks » Burgandy Melfort Stick
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The walking canes in the Melfort range have small handles and are overall lightweight and dainty. This stick has a total height of 91cm (36 inches) and a diameter of 21mm under the handle, tapering down to 18mm at the tip. Finished with a collar around the neck and a rubber ferrule on the tip, this walking stick would make a very nice gift for a lady.
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Total Posts: 457
Joined: May 2006
2018-02-06 11:33
Any thoughts on what is driving the repricing in the markets this week?
I mean, we all know the equities are massively overvalued, and they still have a long, long way to go before they can be considered to be fairly priced.
But people don't generally wake up on a bright Friday morning, after 8 years of driving the markets to record highs, and go "oh sh.t, this is overvalued - we have to sell everything today". Based on no news whatsoever.
My personal bet would be on one big seller, triggering the nerves of lots of people who have been fearing a sell-off for a long time.
Any thoughts / gossip / insights?
"There is a SIX am?" -- Arthur
Total Posts: 368
Joined: Jan 2015
2018-02-06 12:27
The below is unsubstantiated hearsay from some friends in rates space, so take with a grain of salt...
Japanese pensions and insurers have been loading up on duration to reach for extra yield. Up until last year, this mostly worked, because rates were going to stay 0 forever. As the trade got more crowded they kept increasing exposure to maintain the same same yield enhancement. Well, obviously this has been pretty painful so far in 2018. Finally the pain of losses in treasuries broke the camels back on Friday. There's been a major long squeeze in treasuries. As positions get liquidated, the contagion has spilled over into equities. Regardless of the specific details, it seems pretty clear that this selloff definitely originated in treasuries.
Good questions outrank easy answers. -Paul Samuelson
Founding Member
Total Posts: 5084
Joined: Mar 2004
2018-02-06 12:46
The pensions rebal has been a point of speculation for weeks, given how overvalued equities are. Married to this has been speculation about how much within that has become risk parity. People are concerned about the institutional pressure at the long end coupled with general FED. At the short end there was discussion around removing GC from the leverage ratio calc and we saw this normalize o/n.
The better jobs / higher wages data was definitely the big nudge. This inflationary signal created uncertainty at the wrong time. In addition to pensions, and ever since '87, there is speculation around programmatic trading. While present, based on my calcs, this is always overestimated, especially since summer of '15. I do not think that there's been any meaningful delevering. On the other side, I don't think there was as much momentum-based "buy the dip" as we've previously seen, making most of these things intraday events. Instead the bottom didn't push back.
VIX had it's largest move, ever. This coming off a series of spx up / vix up moves. rates and equities were down yesterday. Double digit bps. This has people spooked. Friday option flows were choked. Yesterday was better. Pricing in FED and institutional / programmatic will take a bunch of the tension out of the shape of things.
Nonius is Satoshi Nakamoto. 物の哀れ
Total Posts: 457
Joined: May 2006
2018-02-06 17:09
Thanks both.
It's one of those things that people throw around, but it doesn't quite add up in my mind.
Inflation => treasuries. Fine, no argument.
And then what? Inflation is high so you prefer cash to equities?
The dv01 of equities would have to be 20 for that side to work. It might just be me, but I don't see it.
"There is a SIX am?" -- Arthur
Total Posts: 432
Joined: Dec 2008
2018-02-06 20:49
Ronin- thanks for your patience with my stupidity
Is DV01 for equity well defined?
Is it appropriate for stocks w/out distributions/dividends?
Does it capture the many impacts of inflation on an operating company's performance beyond the cash flow opportunity cost? (inflation hits company in nonmarket space)
EDIT: minor clarifications
Total Posts: 432
Joined: Dec 2008
2018-02-06 21:01
Rapidly compounding said stupidity
Is equityduration = Price / div the kind of calculation you have in mind?
or on a related note, there's this, err, source who points out that if debt is impaired, equity is impacted...
Total Posts: 457
Joined: May 2006
2018-02-07 10:11
Thanks @deeds!
By dv01 I mean sensitivity to interest rates. And that is kind of my point. Equity dv01 isn't even particularly well defined, let alone easy to measure. And yet we seem to be saying that a quarter point interest rate rise (or 20-30 bp of treasury yields) is worth 5-10% of equity prices, minus inflation.
That would be dv01 of at least 20. And then add the effects of inflation, which pushes it even higher.
Like I say, doesn't quite compute.
"There is a SIX am?" -- Arthur
Total Posts: 432
Joined: Dec 2008
2018-02-07 12:24
Ronin - I see your point.
Parking the question about how interest rates impact equity in detail, it seems an assumption of linear or smooth response underlies the expected response of the equity markets.
In my mind maybe there is scope for a picture that is more 'tectonic'...equity investors primed to move for a protracted period, with a kind of built up pressure leading to an overresponse.
I remember someone in the forum describing how they perceived a particular financial crisis (maybe it was peso fx crisis or argentina)...very slowly for an extended period, then very fast.
Total Posts: 2864
Joined: Feb 2005
2018-02-07 13:36
Inflation => treasuries. Fine, no argument.
And then what? Inflation is high so you prefer cash to equities?
The usual argument goes like "Equities are overvalued, but relative to bonds the divy yields rock". Now higher inflation would mean higher nominal rates at the long end and all of a sudden dividends look a bit... less attractive. But 2y Treasuries beat divy yields for a while now so this isn't exactly news.
As for the risk parity guys, I expected them to move after the snafu in VIX. Given the rumored amounts in various short vol strategies the moves so far seem rather harmless, though.
"He's man, he's a kid / Wanna bang with you / Headbanging man" (Grave Digger, Headbanging Man)
Total Posts: 10
Joined: May 2018
2018-05-22 11:22
Thanks for the useful information! You helped me with advice!
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Last year, we were introduced to the FRIDAY BY FRIDAY brand as Creative Director + Designer, Friday Lynton prepared to launch her 5th collection, "Season 5." In our first interview with Friday, we discussed the beauty and importance of women empowering each other and how she aims to integrate that message into her unique line of chained objects. This summer, FRIDAY BY FRIDAY is back with a new collection for Season 6 and an even deeper message to convey than last time.
"For Season 6, I dug a little bit deeper. It's not so literal. Last season we definitely presented the idea of FRIDAY BY FRIDAY being for all types of girls, the unity of women, and we expressed that through the fashion presentation and the imagery from the Season 5 campaign photos. This time around, it's more of an open diary; the open diary of an artist in a sense with it being an exact reflection of an experience that I've actually gone through as an independent artist throughout the ending of Season 5 up to the beginning of this year. It's expressing moods of anxiety, and feeling broken as an artist... Feeling like you're not good enough and feeling like you may not actually have a shot or a chance at what you're doing... Doubting yourself and not believing in what you're doing... Following that process and learning that, that's something everyone goes through — not just artists. Artists are, more specifically, what we're targeting for this one but it's definitely something that I know people will be able to relate to regardless of what creative journey they're going on."
Being a female boss in today's world comes with a lot of pressure; especially with regard to our image and our portrayal on social media. We often feel as though it is our responsibility to always keep our shit on point and make everything look polished and pretty for our followers, even if we're lowkey on the verge of completely losing it. With this Season 6 collection, FRIDAY BY FRIDAY will shed light on a few of these raw and unglamorous moments by letting the world into her personal artist's diary.
"Season 6 is about being young and knowing that not every moment is happy. With a lot of fashion campaigns I see, everything's so happy. Everything's so cute and like, "We're hot and we're boss babes." That's empowering and it's great, but the story I wanted to tell this time around is what happens when that girl is not on social media, flexing. Or what happens when that girl is not at the party looking great. What does that girl do behind closed doors? You may think that she lives this amazing life but she might actually be struggling as an artist or going through her own shit. I definitely wanted to kind of dig a little bit deeper and kind of take a page out of a certain mental diary that I have and express it visually for people to see. And it feels really weird, I've never felt this vulnerable. It's a little bit scary because it's kind of like your mom finding your diary at 16 years old and she's like reading it and you're cringing – that's kind of how I feel now. Expressing shit that I've been through and being very open about it."
Whether it's music, visual art, or fashion, we (as humans) crave to indulge and consume things that we can relate to; things that we can connect with. The greatest artists are those who have been able to find the courage to be vulnerable and open when creating, because that sense of transparency is what allows others to connect to their work... And with this new collection FRIDAY BY FRIDAY does just that; it provides us with something real that we can feel.
"It's important to show both ends because we're in this world of social media and a lot of what we see is so pretty and well curated. I wanna see the messy stuff, I wanna see the breakdowns, the 2 AM you have a final project and you're in tears. The on the ground, not knowing if you're going to be able to pay your rent next month because you know you might not have made a sale in two months. I wanna see that, so that's the reason why I decided to create this imagery, because it needs to be shown… It's not shown enough."
FRIDAY BY FRIDAY's chained objects link avant-garde fashion pieces with the down to earth, cool, millennial woman. Worn and adorned by girls like Justine Skye and Keke Palmer, it's a brand at the forefront of trendsetting and on the brink of changing the way things work in the fashion industry. FBF is set to drop a wide array of new pieces along with some additional amazing projects like a fashion film and an editorial blog.
"Since the last time we spoke I've been planning and preparing for the fashion film (that's going to be released on the brand's anniversary on July 1st), the fashion presentation and the campaign photos. I've been working on a full collection this time around which is gonna be dropped in three stages, so the collection will build as the summer goes by. To sum it all up, I've just been trying to build this concept of what FRIDAY BY FRIDAY is and who the people are behind it. We are also re-launching the GIRLS IN FBF style blog. It's gonna be a blogtorial, like a blog editorial... So that's going to be really big! It's going to be more interactive in a sense because we want the platform to be broader. I hate when I go on clothing or shopping sites and I'm literally just there to shop and there's nothing else for me to see or interact with. It's just like, 'come on here, buy stuff, and leave' – that's how I feel most of the time. What I really wanted to do was extend the platform and create this blogtorial so that we can feature really great, empowered girls wearing FBF. They can tell their story, we can do cool shoot collaborations, a lot of original content of editorial work collaborating with other female photographers, models, artists, and so on. We're really excited about that as well. That should launch in late June."
The new Season 6 collection will consist of chained tops, a larger selection of dresses, chokers, accessories, and even a chained trench coat that Friday has been working on for a very long time.
"The collection is very hefty; aiming to target different pieces in your wardrobe and providing more than just a choker and a top. I want people to have more FBF in their wardrobes so that they can style it differently and wear it with different types of things. Tops, skirts, dresses, a chained bag, the trench, I have like a water jug and a couple of fun things. There will also be merch as well that's going to go along with it."
As mentioned before, parts of this collection will be dropped on three different dates throughout the summer (be sure you're following @FRIDAYBYFRIDAY to stay updated -- the first drop will be on 06.23.17). You can shop the collection at any point following the release, but there will be cut-offs after a certain number of sales for specific styles. This provides FRIDAY BY FRIDAY customers with the security of exclusivity and an authentic boutique shopping experience.
The process of making Dreams And Real Life Align is a constant stream of new lessons. Creatives are always learning and growing into the type of people they want to be, both professionally and personally. Before we wrapped up our interview, Friday shared some of the lessons she's learned and how she's gone about translating them into her work.
"I've learned to be a lot more vulnerable with my work. I've learned to open up more. I've learned to take my time a lot more. There's like a ton of lessons. With age you grow and try things, and some things may not work so you do what you can until you figure a better solution. I've definitely learned new techniques. I'm introducing some new chained patterns. The way I weave the chains together; I've learned new ways to do that, that are a lot more intricate and a lot more interesting. That will be shown in some of the pieces. I learned how to make a trench, which is an amazing accomplishment for me. In the beginning I only really knew how to make tops and very simple things. Being able to conceptualize a coat out of metal is like mind-blowing to me. With all of the details — the collars, the sleeves, replicating buttons and all those sorts of things. The design aesthetic definitely stepped up a lot. The storyline is way more real to me; I've learned how to be vulnerable and kind of give myself as an artist to my work and to my audience and not hold back. Designing, the process, creating, everything has stepped up and it's definitely going to show once the collection drops."
Be sure to follow FRIDAY BY FRIDAY on Instagram + Twitter; this will keep you updated with releases and information about the Season 6 fashion presentation taking place in NYC on July 1st. You can shop on their amazing site FRIDAYBYFRIDAY.com and learn more about the vision behind the brand!


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Xander and all of my kids had their winter music recital today. Have I mentioned how much I like the way that Shana and Hannah do recitals? They start on time, take only an hour including refreshments at the end, finish on time and have frequent breaks that include all the kids in the audience. Such a great experience for the kids (and I'd be remiss if I didn't also note that if you are looking for piano lessons we think MYC is amazing and Shana and Hannah are fantastic teachers)
The recital was at the Steinway Piano Gallery, who are apparently allowing the sticky-fingered rug rats of Ottawa to run around their showroom containing at least a million dollars worth of pianos and to actually play their pieces on their top of the line concert grand (sticker price: ~$225,000) This is likely the best piano Elizabeth will ever touch in her whole life. Lorianne was pretty psyched to be able to try it out herself. We think she might have appreciated the experience more than the kids did (hee!) Her mom was visiting so we dragged her along too. Grandma J and Auntie Janice completed our cheering section!
This was Xander's first piano recital and he seemed completely unphased. Matthew was a little unsure at first as there were a lot of people he didn't know but soon got into it. He sure is an enthusiastic singer!
Titus made his first appearance tucked into Mrs Hannah's pouch with brother Timmy. It was also Amelia's first music recital. She totally puked on the floor right before the recital started (thanks Uncle Dave for cleaning the floor) and wanted to eat her instrument rather than shake it but I thought she did pretty well for nine months...
Elizabeth completely surprised us by having a fit of nerves. My aunt Joanne is a very talented pianist and composer. Elizabeth received some of her music for Christmas and is very determinedly was working away at some of the pieces. "Firefly" particularly caught her fancy and she practiced it so often that some of her other class pieces suffered a bit. We were explaining this to Mrs Shana, who suggested Elizabeth might like to play Firefly for the recital. Well, Elizabeth went up to the piano all by herself at her first recital when she was not quite five and wasn't nervous at all, but this time she was SUPER nervous to the point that we thought she was going to cry when she performed it in class.
"Everyone will know that I'm different" she explained. "It's not in the fat book!" She insisted on playing it very slowly and with me pointing, so it definitely was not her best rendition. Honestly I should have refused to help as I was a hindrance rather than a help. She also normally holds down the pedal, but "couldn't find it" on the super fancy piano. Never mind, she still did an awfully good job and we are super proud of her.
After the recital, the kids all got glow bracelets and candy as a treat. Matthew had his on his wrist and was proudly examining it at every opportunity. Next thing I know it had somehow cracked open, gushing up his nose, into his eyes, mouth and all over his dress shirt. Auntie Janice helped me flush him out a couple of times while he hollered and tried to run away (poison control later told us they recommend at least ten minutes - that might have required more than two adults). He's fine, but not sure what he thinks of glow bracelets anymore...
PS You can hear (and buy!) Joanne's music, including what the piece sounds like when Joanne plays it on her website at www.joannebender.com
We had enough snow to make a pretty decent fort. The kids made a snowman to guard the front door. I did most of the digging of the fort. Elizabeth complained that I made the roof pretty thin as she wanted the fort to last a long time but I was worried about a potential collapse so they had to make do.
I drew the line at making more than two bedrooms. There's an emergency slide, steps, a kitchen and play area. But mercifully they agreed that if anyone needed toilet facilities they could go inside.
Auntie Janice here. As most of you know, lately there's been a lot of ambulances visiting our house… all for me. The count stands at 9 visits to hospitals- 8 of which involved epinephrine.
I swear I'm not playing hospital bingo, but I've been recognized by the same paramedics, the same triage nurses, the same nurses, and an ER doc who recognized me from an allergic reaction several years ago… I've visited all the hospitals in the city, and even stayed in some of the same beds. So if there was such a thing I think I've won. Sigh…
The other day at Brownies, we had an ambulance visit for our First Aid badge. One of the Brownies came downstairs and said "Pygmy Owl (that's me), I didn't know what we were doing tonight, so when I saw the ambulance outside I thought it was for YOU!". Clearly we've had enough random conversations that my Brownies are really starting to understand allergies, lol! For example… Brownie: "WHY do you have that HUGE bruise on your arm, Pygmy Owl?" Pygmy Owl thinks for a minute… hmm… how to phrase this… I had another allergic reaction last weekend at work, and the nurse couldn't find my veins for an IV, so she gave me Benadryl in the muscle, and went really deep or something and it bled a lot. "I had another allergic reaction last weekend, and the nurse didn't do a very good job of giving me the medication. But, the medication helped a LOT so I don't really mind that I got a bruise."
The good news is that the allergy testing does seem to have given us some leads. To the previous list of 13 fruits, vegetables, and nuts… I have added black pepper, bell pepper, and a couple extra nuts. My allergist also highly suspects an allergy to sulphites, which are apparently in EVERYTHING. They occur naturally in many foods such as onions, garlic, soy, maple syrup, and cheese… they are added to almost everything pre-made including salt, spices, alcohol, gelatin… and they are heavily used in processing things like starches, corn syrup, and anything dried. By cutting out most sulphites, I've reduced my hospital visits down to: no food related ones! I say "most" because I'm still working on finding sources of sulphites- I still get hives pretty regularly- and it seems my regular medications may be a source. BOTHER. Thankfully my pharmacy is a compounding one and they may be able to make a custom version that doesn't involve gelatin, starch, or citric acid :D YAY!
For now, I won't be eating much of anything I didn't make myself from scratch… which has been occupying about 14-24 hrs a week as far as I can tell. I finally have a week's worth of frozen meals in my freezer, and am hoping that with another few baking sprees perhaps I can keep it at two weeks! That would be nice. To combat the inevitable boredom associated with eating the same ~35 ingredients every day I've taken to having a little crazy fun like shaping my ground beef, or making all my pancakes into owls. In my opinion, the grapefruit toffee is pretty good- though both Elizabeth and Matthew are not fans. They much prefer my sweet potato chips, but with a small container requiring about 7 hours to make… I'm not likely to be sharing many! I've rationed them out to last me as long as possible, as snacks are a luxury these days.
52 cm of snow at once! The kids were SUPER excited and I might have been a wee bit too! It was also a snow day. We didn't drive Elizabeth to school but we did all go to music class and then to the library. Elizabeth was pretty pleased to get to be Amelia's "helper" for music "... because I'm really too big to go to a baby class now Mom" said she, sparking fury from Matthew who was not happy about his beloved music class being characterized as for babies. Although there are definitely babies who participate and Amelia isn't even the youngest anymore!
By the time we got home around noon the snow was coming down heavily enough that I cancelled any ideas I had about driving anywhere else for the rest of the day. The plows were having a hard time keeping up and even the main roads were pretty terrible.
Eventually it stopped snowing quite so much and we decided we needed to clear the driveway. I was borrowing some snow shoes from Grandma J so the kids and I promptly put on our snowshoes and headed outside. I even shovelled a bit, wearing snow shoes with sleeping baby strapped to my chest. Does it get more Canadian than that?!?! Elizabeth was running up and down snow banks and generally having a blast. Matthew had a bit more trouble as he kept stepping on his own feet and having to be hauled back up but loved the snow!
There's a new app for tracking your snow plows in Ottawa this year and it's been pretty terrible so far. But this time after it went all day telling us that it wasn't about to give us an estimate since residential road plowing hadn't started yet (fair enough), when I finally checked the estimate was pretty good. Mind you, it had previously told Brendan 20 minutes about an hour and a half before that. But I still think it's an awesome concept and every storm they are getting better... Plus it's amazing to me that people basically still all went to work and we still received courier packages etc all day.


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Star Coral Textured Small Bowl in Kelp Forest
Star Coral Textured Small Bowl in Kelp Forest
This hand textured bowl features our star coral design and is glazed a color we call Kelp Forest, because that's exactly what it reminds us of! A beautiful teal glaze is flecked with golden and bronze accents that move toward the center of the bowl. The exterior is left unglazed, providing a bright alabaster look and a raw, tactile feel. This bowl makes a great addition to your decor on a side table, shelf, mantle, or anywhere else!
Pictured is the bowl you'll receive.
Approximate Size: 7" in diameter and 4" high.
This glaze is foodsafe, however due to surface characteristics, we recommend only using these dishes to serve "dry" food (nuts, candy, dried fruits, etc). Additionally, this glaze may crackle slightly; please see our FAQ page for additional information.


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Little is known about the auto at this stage, but Tesla founder and CEO Elon Musk has said it will have falcon wing doors (opening vertically, like on the Model X).
After describing the past few months as among the most "hellish" in his life, Musk said he expected Tesla to post a quarterly profit during the July-September period.
"It's very hard to become a mass-manufacturing auto company", Musk, 46, said after shareholders voted down a measure that would have required an independent director replace him as chairman.
Tesla's (TSLA) stock rallied nearly 10% during market hours today following CEO Elon Musk showing a lot of confidence during the company's annual shareholder meeting.
This was in spite of some stakeholders raising concern that a board with these directors lacked independence. "We're confident we know how to address them".
Manufacturing bottlenecks have delayed the delivery of vehicles to customers and deferred much-needed revenue as the company continues to spend heavily on Model 3 production fixes, as well as projects in the pipeline.
Tesla has plans to build a rival to the Volkswagen Golf, Ford Focus and Vauxhall Astra within five years.
Musk appeared on stage visibly shaken with a quiver in his voice.
Contrary to recent press reports asking if Tesla might be abandoning the mass market and what happened to the $35,000 Model 3, Musk assured investors Tesla has not given up on plans to manufacture the base-level version of the vehicle.
Major shareholder funds group CtW Investment Group wants to see the voting results.
The move would have removed Musk as chairman of the Tesla board. Musk reiterated previous predictions that that will happen during the second half of this year. Here are the 5 big things Tesla are doing right now.
Tesla had recommended shareholders leave Musk with both top jobs and argued the directors are qualified. The goal, said Musk, is to be able to go nearly anywhere on earth using the Tesla Supercharger system.
It now looks as though 5,000 per week is going to be achieved before the end of June.
"Model Y, for example, will not have any leather in it, including in the steering wheel - even if it does have a steering wheel", he said.
While Musk also holds the titles of founder and chief executive at Tesla, losing the chairmanship would significantly reduce his influence over the company, in which he has a 20% stake. "Next quarter, at the Gigafactory, we expect to make more battery capacity than all other EVs combined worldwide, including China". Still just one-third complete, it already takes two hours to walk the length of the factory floor, according to Musk.


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Steitz Secura All-round ESD 782 Plus Safety Boots
Available Options
With Steitz Secura's original multi-width system, this functional boot is available in three different width sizes to specially suit the wearer for maximum comfort. Please note that some widths may be made to special order – we recommend to check with us via. our Online Chat Service if delivery is time sensitive.
Made with soft, nubuck leather; featuring reflective applications.
- Aluminium toe-cap
- Breathable, adaptable lining
- Removable ERGO-SOFT ESD insole provides additional cushioning and excellent moisture transportation
- Best possible scuff-resistance
- Anti-slip
- Heat-resistant outsole (up to approx. 120°C)
A SECURA VARIO System actively reduces pressure loads within the boot and gives targeted relief.
- Tested and approved to EN ISO 20345:2011
- S2 and SRC rated
Delivery Information
If kept in stock, goods are routinely dispatched within two working days from our warehouse in Cheltenham by 24hour carrier or through our own local delivery van service. Special or urgent deliveries can also be arranged if required.
If supplied to order, items will be immediately dispatched as soon as possible. Please note that due to some of our products being specially manufactured outside of the UK; lead times may vary.
Need to know an item's stock status? You can now double-check with us easily via. our Online Messaging Service. Just look out for the icon in the bottom right-hand corner of your screen.
For customers located within Gloucestershire, UK, and for all orders over £150nett, delivery is FREE. Otherwise carriage is charged at a normal rate of £7 plus VAT (for most mainland destinations). Destinations outside of UK Mainland may be subject to different terms and conditions.
When purchasing with a credit or debit card, your billing and delivery addresses at check-out must match for security purposes. For delivery to an alternate address, please contact us.
We believe that supplying the right product, at the right time, is fundamental to our business – and so we stand as one of the first safety equipment distributers to become registered under the Quality Assurance Scheme to BS EN ISO 9002 (now 9001).


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As new cars roll off the production line, more and more models are being developed with a new technology called Active Headrest Restraint. In 2011 more vehicles have been introduced with this technology.
Active headrest restraint is a technology where the headrest pillow will activate and move up and forward to help reduce the distance a head moves during an accident in hopes of reducing the possibility of whiplash injury. While our built-in headrest DVD players are very popular, we don't recommend replacing the headrest pillow to your vehicle if it has active headrest technology built-in.
To see if your vehicle is equipped with the active headrest restraint technology, check your owner's manual in the safety section and see what it says. If your vehicle does have active headrest restraint technology, we have the solution for your back seat entertainment needs.
Introducing to you first from OnFair the Autotain active headrest car DVD monitor solution. This car DVD player model attaches to your existing headrest posts as a headrest DVD player as well as becoming a portable DVD player by dismounting and enjoying in the home or on the go.
Please note, this headrest DVD system can be enjoyed on vehicles with active headrests as well as vehicles without active headrests. Check out our short video for more details.
The Autotain EDGE is one of the most advanced active headrest DVD players on the planet!
SMART HDMI connectivity on the road to your smart phone, iPad, iPhone and other Android devices.
Enjoy in the car and in the home with the included 3 power options: cigarette plug, fuse box and home.
The audio video pass-through feature offers unlimited connectivity between headrests and in-dash units. Yes, connect your in-dash to 1, 2, 3 or even 4 headrests without any additional wires or splitters.
Many video options at your fingertips. DVD, CD, MP3 files, SD card, USB and two RCA a/v inputs.
Check out the AUTOTAIN EDGE Active Headrest DVD Player here
The Autotain MEGA is the LARGEST headrest DVD player monitor on the planet!
Amazing picture with 1080p LED screens. HUGE 1920x1080 resolution.
SMART HDMI connectivity on the road to your smart phone, iPad, iPhone and other Android devices.
Enjoy in the car and in the home with the included 3 power options: cigarette plug, fuse box and home.
Many video options at your fingertips. DVD, CD, MP3 files, SD card, USB and two RCA a/v inputs.
Check out the AUTOTAIN MEGA Active Headrest DVD Player here
OnFair is the leading online provider and most passionate about offering only the best headrest DVD players on the market. They work directly with factory engineers to design and develop the most advanced features and capabilities available and then offer them to you in their exclusive AUTOTAIN branded headrest monitor packages.
Because they've been doing this for over 11 years as a family business from Lincoln, Nebraska, some would argue they've earned their PHD in headrest DVD players as it'll be nearly impossible to find anyone more passionate and more experience with the product.
Want to know more about the OnFair story, check it out here.
OnFair About Us – Let's Make Travel Time Part Of The Family Fun!
It's keeping your kids entertained! Every mom and dad can answer it in the blink of an eye! There's nothing more challenging than finding the right toys and gadgets that will keep your little ones engaged and offer you the peace of mind to focus on the road ahead!
Allow me to introduce myself. My name is Brandon and I'm a proud husband of 22 years, father of 2 and the founder of OnFair. We absolutely love taking long family trips across the country and discover the mesmerizing beauty of nature. But as you already know, the journey is as important as the destination! And being on the road with 2 little rascals can be a handful.
Let me paint you a word picture. You're driving on route 66, it's getting dark and your children are starting to get fussy. You take out their tablet but that's when the fighting starts. They both want to hold it and play different games. Then comes the crying, then comes the screaming and finally you've had enough. You finally decide to pull over and play referee.
That's when you see a car passing by with 2 children in the back seat laughing and enjoying themselves.
It's not magic, it's just the OnFair headrest DVD player! The ultimate auto entertainment solution that takes all the hassle, crying and fighting out of family trips!
After tons of road trips, I've decided to make family vacations more fun for both parents and children! Our headrest DVD players are designed to offer your kids endless hours of excitement while allowing you to enjoy a calm and relaxing drive.
OnFair is a family-business aimed at families! Our goal is to keep mommies and daddies happy by providing them with the ultimate headrest DVD player! Ever since we designed our first product, we have been constantly upgrading it in order to keep up with the latest technology. We are based in Lincoln, Nebraska, so our family-oriented approach is a result of our Midwestern values!
And unlike other cheaply-made knock-offs, our DVD entertainment center has a name! It's Autotain and it's here to make your family vacations a tiny bit more fun!
Popular Models


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Rossi: Rubino (8626) (6mm)
Product Number: 002-577-4665
With its low-gloss, semi-matte finish and subtle contrast stain, Rossi's Rubino just makes for an excellent way to present the marque's range of classic shapes, like this squat, supple bent Apple.- Andrew Wike
Your PriceSold
Ask a question about this product.
The pipe you see is the pipe you receive. Click here to see our photography process.
Measurements & Other Details
- Length: 5.19 in./131.83 mm.
- Weight: 1.50 oz./42.52 g.
- Bowl Height: 1.72 in./43.69 mm.
- Chamber Depth: 1.35 in./34.29 mm.
- Chamber Diameter: 0.75 in./19.05 mm.
- Outside Diameter: 1.52 in./38.61 mm.
- Stem Material: Vulcanite
- Filter: 6mm
- Shape: Bent Apple
- Finish: Smooth
- Material: Briar
- Country: Italy


text: Breadcrumb Home > Dictionary Search Cite Meaning of slave Find definitions for: slave Pronunciation: (slāv), [key] — n., v., slaved, slav•ing. —n. a person who is the property of and wholly subject to another; a bond servant. a person entirely under the domination of some influence or person: a slave to a drug. a drudge: a housekeeping slave. a slave ant. a subsidiary flash lamp actuated through its photoelectric cell when the principal flash lamp is discharged. a mechanism under control of and repeating the actions of a similar mechanism. Cf.(def. 19). —v.i. to work like a slave; drudge. to engage in the slave trade; procure, transport, or sell slaves. —v.t. to connect (a machine) to a master as its slave. to enslave. Slave Pronunciation: (slāv), [key] — pl. Slaves, Slave. a member of a group of Athabaskan-speaking North American Indians living in the upper Mackenzie River valley region of the Northwest Territories and in parts of British Columbia, Alberta, and the Yukon Territory. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: slave (Thesaurus) Slav slave ant Related Content Daily Word Quiz: sylvan Analogy of the Day: Today's Analogy Spelling Bee: Today's Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language


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The Furniture Sales Guide
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This one has been around for a while, but I thought I'd mention it here… one of my clients recently received this SCAM email from a Hong Kong email address claiming that their domain name was 'in dispute'. If you receive an email like this, do not reply to it, do not save it, just delete it. It is a scam that will probably end up with the sender trying to get hold of your bank details. Common sense suggests that if there really were an issue with your domain name, the person with alleged IP rights on the domain name would write to you, or would take it up with the domain name registrar.
This is an extract of what was received:
Dear CEO & Principal:
We are a domain name registration and dispute organization in Asia, which mainly deal with the global companies' domain name registration and Internet Intellectual property right protection. Currently, we have a very important issue needing to confirm with your company.
On April 8,2010, we received an application from one company named "******" who wanted to apply for the Network Brand " domain name" and some related domain names through our organization.
Now we are handling with the registration of these domain names and find that the keyword of these domain names and Network Brand is identical with your company's. According to our technique department's investigation, ****** does not have prior rights to this keyword but you do. So we have to confirm with you at two points:
1. If your company consign****** to register these domain names and Network Brand, we will send application form to them and help them finish the registration at once.
2. If your company have nothing to do with ******, they maybe have other purposes to register these names and Network Brand.
We have suspended their application and can not proceed before we get your confirmation. If you are the corporate representative of your company, please reply this email and I will feedback some problems to you; If you are not, please forward my message to the right person or department soon.
Hope that helps!


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As part of a National Trust wide conservation event to control non native invasive species, please come and help us clear Himalayan Balsam from the Valency Valley in Boscastle. Gloves will be provided but wearing wellies would be handy!
Come for a couple of hours or bring a packed lunch and stay for the day.
Meet in the main car park in Boscastle at 10am
Simon Ford – the National Trust's Nature Conservation Advisor in Wessex explains what the problems are and what we are doing about it
NT – Plant Invaders Week from National Trust on Vimeo.