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I was so surprised and pleased to find out yesterday that the American Bald Eagle, iconic symbol of America, was removed from the threatened and endangered animal list on Thursday by the federal government. We can all celebrate the Fourth of July this year knowing that this proud symbol of America will be around awhile longer.
This comeback is considered one of America's great conservation stories and thank goodness. We certainly wouldn't have wanted our National Animal to have died off. This would be bad karma, or an ominous omen, or even an unfortunate metaphor for those in power making poor decisions.
The eagles have been in danger of extinction since the mid 1960s when the combination of DDT's (now banned) and overly aggressive hunting severely diminished their numbers. Here in the San Francisco Bay Area, we now have over 200 breeding pairs, and nationally we have nearly 10,000. This is up from the frighteningly small total number of fewer than 35 pairs America had in the 1970s, but is still only half the historical high of 400 pairs California had before the problems affected them. Many of the eagles were bred at the San Francisco Zoo in the eagle's captive breeding Species Survival Program. This program has been so successful that the breeding pairs will now be sent off to Tennessee to help expand the bald eagle population in the South.
At Kyle Design, eagles are very popular collector items, especially our money clips and night lights. If you know one of those patriotic individuals who has an eagle collection and are shopping for a unique American made piece to add to it, then you'll want to check out our Artistic Eagle Gifts and Decor page.


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CHICAGO -- A therapy aimed at reviving the immune response to advanced melanoma generated durable responses in long-term follow-up of an early clinical trial, a researcher said here.
About a third of the 107 patients in the dose-finding trial had an objective response to the monoclonal antibody nivolumab, and the rate reached 41% among patients who got the dose now being studied in phase III trials, according to Mario Sznol, MD, of the Yale Cancer Center.
In contrast, historical response rates to immunotherapy in advanced melanoma have been no better than 10%.
"We're really in an era of remarkable advances in melanoma," Sznol told reporters at the annual meeting of the American Society of Clinical Oncology.
The drug targets a molecule dubbed PD-1 -- part of a so-called immune checkpoint -- on the surface of killer T cells. PD-1 is activated by a corresponding molecule, PD-L1, on the surface of tumor cells, with the effect of turning off the immune response to the cancer.
Nivolumab is one of several drugs under investigation whose goal is to interrupt that activation and keep the immune response active. The meeting is expected to see reports on others that block PD-1, as well as some that block PD-L1 on the tumor side of the interaction.
For the near future, the study emphasizes the importance of getting patients into clinical trials of new drugs, commented Lynn Schuchter, MD, of the University of Pennsylvania in Philadelphia, a melanoma expert who speaks for ASCO.
"Patients with melanoma getting access to these new agents is really the most critical part of care," she told reporters.
But "when PD-1 antibodies get approved, it will definitely be practice-changing," she said.
"Melanoma patients are living longer and better with these new treatments," she said in a statement.
The industry-sponsored study tested nivolumab in several types of advanced disease, but for this report, Sznol and colleagues focused on the 107 patients with advanced melanoma.
All patients had disease that worsened despite earlier standard systemic treatment. Indeed, 25% had three or more prior therapies and 63% had two or more, Sznol reported.
The drug was given intravenously every 2 weeks at doses ranging from 0.1 to 10 mg per kg of body weight.
Overall, 31% of the patients -- 33 of the 107 -- saw their tumors shrink by at least 30%, with at least some responses at each dose level.
The researchers chose a dose of 3 mg per kg for further study because of a 41% response rate, including one patient with a complete response, Sznol reported.
That dose also had a median overall survival rate of 20.3 months, compared with 16.8 months for the study as a whole.
The drug caused adverse events in 82% of patients, with grades 3 and 4 events in 21%, most commonly lymphopenia, fatigue, and increased lipase.
"The high level of activity observed with this drug opens up a number of avenues for future research to understand and challenge the ways tumors evade the immune system," Sznol said in a statement.
"We're very excited that there is potential for even more activity in combination with other drugs," he said.
He noted that the study was not randomized, but "it had a considerable number of patients and the durability of responses is a sign of very promising clinical activity."
He also said that patients were representative of typical patients with advanced melanoma, rather than being selected for the best chance to respond.
The findings are a "real breakthrough in the treatment of melanoma and possibly other cancers," commented Michael Atkins, MD of Georgetown Lombardi Comprehensive Cancer Center in Washington, D.C.
Physicians have been able to stimulate the immune system in nonspecific ways for several years, he told MedPage Today, but the treatments were associated with "a lot of toxicity." The highly specific nature of the PD-1 antibody approach appears to yield better efficacy with lower toxicity, he said.
But he cautioned it remains unclear if the approach will work in all patients and in all tumor types.
The study was supported by Bristol-Myers Squibb. Sznol reported financial links with the company and several authors reported holding equity positions in the firm.
- Reviewed by Robert Jasmer, MD Associate Clinical Professor of Medicine, University of California, San Francisco
last updated

subset: commoncrawl


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* CBS getting close to $3 million per 30 second spot
* Nielsen poll finds more Americans watch for ads (Adds CBS comments and background on EA ad)
Ben Klayman
CHICAGO, Feb 1 (Reuters) - CBS Corp CBS.N has sold all the advertising spots for the television broadcast of the National Football League's Super Bowl championship game this coming Sunday, the television network said on Monday.
CBS has come under fire in recent weeks from various groups for allowing a conservative Christian group to air an anti-abortion ad, and for barring a commercial from a dating site for gay men as inappropriate for prime time.
In early December, CBS had sold about 90 percent of the available commercial time for the Super Bowl, with prices for a 30-second spot running close to $3 million. The game typically includes 50 to 60 spots.
"Obviously, we went through a tough upfront this year," Jo Ann Ross, president of sales for CBS, told Reuters. "You always go into a market place when you have high-ticket items like the Grammys and the Super Bowl and an Olympic year a little bit with a pit in your stomach, but that pit is no longer in my stomach.
"There's still a lot to be said for live events that garner general interest," she added in a telephone interview.
CBS had a great year selling ads for the NFL season and is running ahead of last year's pace on golf and the NCAA college basketball tournament in March — even closing a deal on Monday morning with an unidentified company for both sports worth more than $10 million, Ross said.
The Super Bowl is the biggest advertising event of the year. Commercial rates run far above what other TV events command, partly because the game draws around 95 million U.S. viewers. [ID:nN25222280]
More Americans enjoy the ads than the action on the field, a recent Nielsen study found. A study by ad agency Venables Bell & Partners showed that 66 percent of viewers remember their favorite advertiser from the 2009 Super Bowl, compared with 39 percent recall of which team won.
Among the top advertisers for this year's game in Miami between the Indianapolis Colts and New Orleans Saints on Feb. 7 are Anheuser-Busch InBev NV's (ABI.BR) Budweiser and Bud Light beers.
A year ago, with the recession in full swing, companies sharply scaled back budgets and sales slowed in the final weeks before the game.
Big ad buyers FedEx Corp (FDX.N) and General Motors Co [GM.UL] skipped advertising entirely on last year's game.
Still, General Electric Co's (GE.N) NBC eventually sold out all the spots for a record $206 million.
Not everything has been smooth for CBS. U.S. women's groups urged the network not to air an ad by Focus on the Family, claiming it has a strident anti-abortion rights message. CBS has approved the ad. [ID:nN26126352]
Last week, CBS rejected an ad from Mancrunch.com as inappropriate, leading a spokesman for the gay male dating website to call the network anti-gay. CBS also questioned the company's credit history. [ID:nN29227781]
CBS reviews hundreds of ads a day for its shows, working with advertisers to rework spots it deems inappropriate. It recently rejected as inappropriate a proposed tagline for Electronic Arts Inc's ERTS.O new "Dante's Inferno" video game, due out Feb. 9, shying away from "Go to hell" in favor of "Hell awaits." (Reporting by Ben Klayman. Editing by Robert MacMillan and Gerald E. McCormick)


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Thursday, July 21, 2011
Start with the end in mind
Today has been such a busy day. Amidst several meetings and projects, I'm preparing a message to bring at the House of Prayer Church in Tampa this Saturday. I'm not even blogging til' after 9 pm, so anyone who knows me well realizes it must have really been a busy day! (I usually blog pretty early and not much gets in the way of blogging.) :::smile:::
Tonight my goal is to finish the message and that will give me another 24 hours to tweak it as I pray over it. This will be a short blog post as I still need to do that, but I thought I would give the first word of advice from me on this subject and that is to START WITH THE END IN MIND.
Of course you are going to pray your guts out and ask God to give you a word for His people, but I don't personally start at the beginning of a message. I don't create an outline and then an introduction followed by point 1, 2 and 3 and an altar call as lots of people advise. I start at the end. I ask, "How do I want this to end up?" or more importantly, "How does God want this to end up?" I pray about getting a vision for the close. I always give an altar call but it doesn't always look or feel the same. I ask the Lord how he wants the ending to go, and then I go from there and build the message from the front end, out.
If you know where you're going, it's easier to develop a plan to get there. Make sense?
So the first question you ask yourself is, "what is my altar call going to look like?" Then envision a plan to get there. More on this later as I go back to finishing my message...
Labels: Ministry, Pastoring, Preaching, Speaking Series, Travel
2 comments:
Good advice. I've been working on a sermon for a while now that the Lord gave me. I have lots of odds and ends but the first thing I had was the ending too. Good then. I am on the right track.
- Deanna Shrodes said...
Yes, makingapearl you go! May God bless you as you prepare...love ya
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Posted By
Stephanie Welle, C.N.S.
Intensive Care (Critical Care)
Recent Posts
Speaking of HealthRecovery from stroke is never easy, but it is possibleSeptember 21, 2012
Speaking of HealthWho is most at risk for a stroke?September 21, 2012
Speaking of HealthHow to tell if it's a stroke and what you can do to helpSeptember 21, 2012
Speaking of Health
Stroke Awareness: Article Series
This four-part series explores strokes. Learn how and why they occur, and how you can take steps to reduce your risk or aid in recovery.
Part 1: What is a stroke and what does it do to me?
Part 2: How to tell if it's a stroke and what you can do to help
Part 3: Who is most at risk for a stroke?
Part 4: Recovery from stroke is never easy, but it is possible


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Par pricecarhire1 dans Accueil le 10 Juin 2016 à 22:02
Cheap Car Hire
Should you know the methods, it's straightforward to seek out a low-cost automobile rental. Learn why it's more affordable to rent a car inside the weekend or for a 7 days. Find out why you should prepay the vehicle and just how you are able to get a number of added hours or an upgrade totally free. Get suggestions for choosing the right insurance.
Cheap Car Rental
The easiest strategy to save lots of cash is usually to compare the different automobile rental agencies' prices. It would be extremely time-consuming to do it your self, but luckily auto rental lookup web sites has been built, so you just must enter dates and place. Then you definitely can begin to see the cheapest price tag for your a variety of auto designs.
If it's achievable for you personally to plan your getaway so you may need the automobile within the weekend, you are able to typically conserve plenty of cash. Typically you can locate unique weekend gives at the automobile rental agencies.
Long term rental can also be a good approach to save some income. Frequently to can rent a car for any week for the identical amount as four or five days.
Do you would like a bigger car product? Then request. The auto rental companies are prepared to buy your loyalty by offering you extra support, so should you inquire for an improve, they'll usually give it for you, if it's possible. But usually do not strategy your entire vacation (and your luggage) on it. Think about it as an additional reward.
There's a great deal of funds to be saved around the insurance coverage. But prior to you say no for the insurance, you need to read the coverage carefully, since it can expense you plenty of cash, in case you are involved in a collision and you will not be insured.
On the other hand the vehicle rental agencies receive a lot of extra funds around the insurance coverage element. So do pick the insurances, you need; no much less and no more.
Normally the rental periods are divided into 24 hrs. Therefore if need the vehicle for e.g. 27 hours, it is wise to wait a few hrs prior to accumulating the auto; or return it several hrs before. You are able to also try to inquire the car rental company if it is attainable to return the car a couple of hrs to late. Usually it really is not a problem, if you inquire for it.
Lastly it really is a good idea to prepay the vehicle. So as opposed to renting the vehicle at arrival in the airport, you need to uncover an excellent cost online and book the automobile ahead of time. Then the automobile will also be prepared for you whenever you get there within the airport.
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There is nothing more frustrating for marketing and sales than to continually be late to the game. Hearing that a customer has already awarded a contract to a competitor can be demoralizing.
Here is the good news. Your marketing data can stop that from happening. In fact, if you take the time to review your marketing data, you might just find a way to ensure you are always first, and never last again.
Understanding What Your Marketing Data is Telling You
Your marketing data outlines past successes and failures. It shows you what digital strategies produced the highest number of leads and how quickly those leads were closed, which ultimately helps you define your sales cycle times.
You can also determine your customer retention rate from your marketing data, and can outline which landing pages have the highest conversion rates. The faster you convert a lead, the faster you have an "in" with the customer.
Knowing which segments of your market are willing to pay a premium is another benefit of analyzing your data. The answers you seek are embedded within your data and it is up to you to use that data to get that all-important first customer visit.
Pinpointing Past Successes
With what segment of your market have you had the most success? Did that success come from dealing with a particular buyer persona or was it driven by a unique product offering? Was that success driven entirely by your digital marketing strategies?
Focus on outlining why your sales and marketing team were so successful. It is possible that your success was driven by a single digital strategy, one that tapped into your customer's needs and one that quickly incentivized that customer to buy. Understanding why you were successful helps you to duplicate success with other customers.
Sales Cycle Times
Knowing which sales close quickly and which take longer helps your sales and marketing team allocate their digital marketing resources wisely. Quick and easy sales help to pad your numbers. Sales with longer cycle times require more planning, take longer for lead generation, and take up more sales resources.
One way to leverage this insight may be to use your easiest selling product as a way into new customer accounts. Your marketing data will allow you to identify which products are easiest to sell and why. You can then focus on those products with a content marketing and digital strategy that nets quick and easy sales.
Identifying Low Hanging Fruit
Why are some of your customers willing to pay a higher price than others? Does it have something to do with their located, their business type, or your product? Does it have to do with your value proposition? Understanding why certain customers pay a premium over others will help you understand how to set appropriate pricing and offer it across your entire customer eco-system.
Your marketing data will help you identify the low hanging fruit in your market. There is a reason you keep winning this business and your data will help you discern how and why you got into a given account so quickly. Isolate why you were successful and use that same approach again and again.
The answers you seek are found within your marketing data. Use that data to isolate your best performing strategies, best content, and best landing pages. Isolating why conversions happen so quickly on some products and landing pages will ultimately help you stay ahead of competitors.
ReachForce helps marketers increase revenue contribution by solving some of their toughest data management problems. We understand the challenges of results-driven marketers and provide solutions to make initiatives like marketing automation, personalization and predictive marketing better. Whether you have an acute pain to solve today or prefer to grow your capabilities over time, ReachForce can unify, clean and enrich prospect and customer lifecycle data in your business, and do it at your own pace.
To learn more about how ReachForce can help you optimize demand generation and your impact on revenue, get a free data assessment and get a demo today.


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Teach diversity, justice, and joy.
Join a community of teachers and families.
Live in Oakland, where culture and sunshine come together.
Oakland is one of the most diverse cities in the country, with a deeply rooted commitment to equity and social justice stretching back decades. Oakland educators share that commitment to equity across a diversity of school models.
Apply here to 2018-2019 teaching roles with district and charter schools across the city.
I want to teachoakland
Click below to apply to the TeachOakland candidate pool for 2018-2019 teaching positions with local district and charter schools. If you're coming from out of state, get information about transferring your credential. If you're not yet a teacher, learn about pathways to become a teacher in Oakland in the coming years.
I teachoakland
Connect with organizations and resources to support your work and development as Oakland educators including fellowship and grant programs, professional development, housing, and credential information.
We are more than recruiting.
We are building relationships.
Our Beginnings
Oakland attracts brilliant, hard-working, and deeply committed educators. We've come from many backgrounds, worked at every level of the public education system from the classroom to administrative leadership, taught in both school district and public charters, from grassroots to national networks.
In 2015, OUSD, local charter organizations and the County came together to form the Oakland Public Schools Equity Pledge, a city-wide partnership to create a public education system that works in the best interests of all students and their families, by disrupting inequity and cultivating excellence in our schools.
As part of this partnership, a Talent Working Group formed, which led a pilot unified marketing and recruitment campaign in 2017 to recruit the best from within and to Oakland, as well as support those in the profession who want to grow and improve.
We worked with Oaklandish to develop the brand with input from diverse teachers across the city. That is how TeachOakland was born.


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By Andrew Liszewski
You can spend hours carving a horrific face in your pumpkin in a vain attempt to scare the neighborhood kids, but no matter what you come up with, I guarantee you won't get results like Todd Harrison did last year. Inspired by a Make post from last Hallowe'en, Todd's jack o'lantern looks innocent enough, until you push its small red nose. At first the eyes will start to glow, giving the button pusher a false sense of security, but a second later a set of 105 decibel car horns will blare, scaring the candy corn out of any trick-or-treaters who happened to be anywhere near his front porch.
Todd's posted a couple videos of the pumpkin 'in action' on his website, as well as a materials list and a brief rundown on how it all went together, in case you were hoping to create your own by the 31st.
[ ToddFun.com – Super scary honking pumpkin ] VIA [ Make ]


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Situated in the grounds of The Bridge Nursery School, our daily aftercare centre accepts pupils between three and 10 years of age.
Girls from Roedean are also welcome to attend. Girls and boys will be accompanied to and from extra mural activities if required.
Homework classes are conducted after lunch has been served and there is supervised play in the garden and playroom. Refreshments are served at teatime. Holiday programmes are held in the first week of the holiday.
Daily from 12:00 – 17:45
- Experienced supervision
- Light lunch, fruit and juice provided
- Holiday Care programme
Head of Aftercare:
Vania Tafur
Tel: 083 387 1878
Email: [email protected]
Aftercare manager:
Tammy Steele
Tel: 071 108 0595
Email: [email protected]


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Daylight Transport: an American success story. Speed is in our DNA.
Daylight Transport, one of the nation's leading expedited Less-than-Truckload carriers, was founded in 1977, when cross country-transit times for motor freight averaged 7 to 15 days. Through innovations like two-driver sleeper teams, Daylight brought transit times down to 3 days (and even 2 days) coast to coast. This kind of speed was unprecedented at the time. Even now, no other LTL carrier can provide faster over-the-road service, consistently, every day.
Innovation and entrepreneurship.
Daylight has grown steadily over the past three decades. A big company now, Daylight still maintains the entrepreneurial spirit, flexibility, and maneuverability of a small business in the American tradition. We have weathered many economic cycles while maintaining a level of service, consistency, and speed ever more relevant in today's Just-in-Time world.
Hallmarks of the Daylight approach, contributing to our continued growth and success, include:
- Direct loading for reduced handling and safer transit (not "hub-and-spoke").
- Investment in IT. Cutting-edge technology for transparency across our enormous nationwide network. Sophisticated logistics management.
- Innovation in services that support lean inventories: Guaranteed Expedited (Urgent Care and Critical Care), Vendor Compliance (reducing cost and complexity of complying with big box retailer rules).
- Customized "Made-to-Order LTL" programs for individual customers to handle exceptional situations.
- A "Strategic Saver" program helping customers save in a variety of areas, from cash flow to inventory to coordination cost.
- A focus on systems and best practices to streamline operations.
- A commitment to education, training, and continuous improvement for our own people.
- Our motto and mission "Learn. Innovate. Succeed." applies to the way we work with our customers as well as with each other.
- A culture of pay for performance: We compensate our people for delivering results.
Daylight Transport takes pride in the fact that many of our customers' businesses have been built on our services. Our speed and reliability have enabled companies to open up new markets and compete throughout the country without incurring capital costs. We continue to champion the values of American entrepreneurship.


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Swallowing difficulty, also known as dysphagia, can occur due to a variety of neurological or functional diseases or conditions, including brain injury, stroke, Parkinson's disease, Alzheimer's disease, multiple sclerosis, head and neck cancers etc. Something as simple as taking a sip of water can be really challenging for some one suffering from dysphagia.
Swallowing difficulty may involve the following:
- Problems moving food in the mouth
- Trouble starting a swallow
- Difficulty getting food down
- Throat clearing after eating or drinking
- Coughing after eating or drinking
- Wet voice after eating or drinking
- Choking
The process of swallowing is an important reflex that is necessary for objecting our airways when eating and drinking. When swallowing is impaired the airway is less protected.
Problems with swallowing can lead to:
- Poor nutrition and hydration
- Decreased energy
- Pneumonia
- A decrease in social interactions that involve food
Speech therapists are trained in the identification, management and treatment of swallowing problems. A Speech therapist can determine what foods are safe, easy and enjoyable to eat, and what exercises and techniques can improve the swallow function. They will work with the client and their families to provide education on the swallowing and how to reduce the risks.
If you or someone you know is experiencing some of these difficulties contact us for an appointment for a swallowing assessment.


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How To List Your FSBO For Free
Average Fizber customer saves $15,000 selling their homes through the Fizber platform. Check classified sites, on the market by owner sites, your local newspaper's auto section, & be looking out for cars with on the market signs by the side of the road. This section has been introduced because of numerous requests from both Costa Rica real estate buyers and sellers of homes here.
Talk to your friends and relatives, if they can accompany you when clients visit your home for sale by owner Also, you can choose any professional agency to give you some additional support. Includes all boat types, personal watercraft, outboard engines, and boat trailers for sale.
No one is more knowledgeable about the home, neighborhood, recent improvements and maintenance costs then the owner. So we decided to give it a try for the $249.00 and at least get some advertising on the property so that it was known it was for sale. The owner of the FSBO should have prepared for this contingency and have the proper forms available.
You can advertise an open house with signs in your yard, posting a notice on local bulletin boards, and by utilizing free or paid ads online and/or in your local newspaper. According to the National Association of Realtors, in 2014 the average For Sale By Owner home sold for $210,000 versus $249,000 for a home sold by a real estate agent.
Also, People looking for private rentals and homes to share in NSW, are free to visit our for lease by owner real estate. Selling your own home in Australia is not difficult, and we provide also provide our clients with other marketing tools needed to market their homes: 'For Sale' boards, property reports, printable brochures, and more.


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A university professor was prevented from taking to hospital a student who suffered serious head injuries at last night's tuition fees protest.
The Independent Police Complaints Commission has begun an independent investigation into an allegation the 20-year-old was hit by a poice truncheon.
Peter Hallward, a Kingston University philosophy lecturer, said police refused to let him accompany Alfie Meadows out of the police cordon around Parliament Square.
The 20-year old Middlesex University student needed emergency surgery after suffering bleeding on the brain.
Prof Hallward came across Mr Meadows shortly after the incident in Westminster Square.
He said: "He was looking for a way out and looked shocked and dazed and had a bump on his head. It was not a cut but an impact wound – he had been hit by a truncheon, it seemed.
"I grabbed his arm and took him to the exit and the police let him go. We had been trying to get out ourselves but it was not easy.
"They would not let us accompany him. We did not know how bad the injuries were.
"He made a call to his mother who was in the demonstration and she heard the call and managed to press the police to let her through.
"If she had not heard that call and they had not found that ambulance it's quite possible he could have died in the street.
"The fact he got hit over the head at a demo is absolutely outrageous."
He said Mr Meadows regained consciousness this morning and could talk and recognise his mother, and was now in a stable condition.
He said police called him this morning about the incident and he would file an official complaint later.


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Email has been sent to with instructions on resetting your password.
Enroll in a Dignity Health account to simplify finding a doctor and scheduling an appointment. Let's start!
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Medical Rehabilitation relies heavily on the human touch and on the partnership that forms between patient and caregiver. Our patients have the confidence of knowing that their dedicated rehabilitation team offers the optimal combination of medical care, therapeutic intervention, and support. Many of our nurses and therapists have more than 20 years of experience in rehabilitation and hold specialty certifications in their areas of expertise. Our patients benefit from the coordinated efforts of an interdisciplinary rehabilitation team focused on getting patients home and back to their lives.
Albert Hwang, MD, our medical director, is a board certified physiatrist. He graduated from The Feinberg School of Medicine at Northwestern University. He completed his rehabilitation residency at the Rehabilitation Institute of Chicago. His clinical interests include chronic pain, electrodiagnosis, stroke, and spinal cord injury.
Jeremy Wren, DO, our assistant medical director, is a board certified physiatrist. He completed a pre-doctoral fellowship in anatomy and osteopathic manipulative medicine, and later graduated from the University of New England College of Osteopathic Medicine. He completed his rehabilitation residency locally at the University of California Davis Medical Center. His special interests include spinal cord injury and musculoskeletal care.
For a personal on-site consultation, referral, or more information, call 916.453.4566 or 800.330.4566.


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Storm-Felled Branches Are Recycled into Hand-Made Lamps
All Images Courtesy of TOUCH Concept Store
Since 2004, designer Megan Finkel has been wandering along beaches and rivers after large storms, picking up broken branches and hauling them home. There she goes to work, stripping the bark, sanding the wood and adding a layer of oil-based paint for color. Once the lightbulb is in place, the result is one of the more original and striking designs I've seen in a while: lamps that stand on reclaimed tree branches.
Finkel's design helps prove that you can make just about anything out of anything. It ranks among the cooler lamps featured on TreeHugger, with the likes of lighting made from aviator sunglasses, plants, and tea cups.
If you're lucky enough to live in New York, you can check out Finkel's handcrafted creations for yourself. They're on sale at the TOUCH Concept Store, a project of Trendland Online Magazine. So to take a look, head to Rivington Design House, at 129 Rivington Street in Manhattan. And if you're not near the Big Apple, don't worry; the lamps are available online as well.
For more stories like this, follow me on Tiwtter.
More unexpected lamps:
LED Desk Lamp Made from Recycled E-Waste
Every Lamp In Buenos Aires Restaurant Made With Recycled Wine Bottles (Photos)
Recycled Juice Boxes Become Biomorphic Lamp


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Chapter 7: Pterrifying Pfeats
The Great Pterodactyl returned from his latest battle with the lemming demi-god Ludvig, in which Ludvig had been hurled into another of those pesky bottomless pits, to find a pile of lemmings on his mountain.
"Brack," G.P. said. "You want to visit other worlds, eh?"
So the Great Pterodactyl proceeded to teach his worshipers of the sacred lever. Flying off, he picked up a huge log, balanced it on his mountaintop and bade the lemmings to gather on one end.
Then the Pterodactyl dropped a boulder on the other end, hurling the lemmings across the galaxy, where they would surely find new and amazing things to fall off of.
His mountaintop cleared, the Great Pterodactyl began to build a huge nest.
"Brack," the Pterodactyl said.
And nobody thought to ask "Hey, why didn't ol' G.P. just carry those guys up there?"
And it came to pass that upon a few of the peopled worlds of AGAR AGAR which the lemmings' trajectory interjected, the lemmings landed amongst the beach parties, yea, they augured into the swamps, the steppes, even the mock-Mediterranean courtyards adjoining the trailer courts. (And due to a typo -- 'interjected' for 'intersected' -- The lemmings were all shouting things like "Hey!" and "Yikes!" and "Golly!" as they hit the worlds of AGAR AGAR.)
And while the people weren't exactly ecstatic at this furry incursion from the sky, they did begin to sing: "It's lemmings, they're pouring / The Great Pterodactyl's roaring!"
However, two lemmings, who were followers of Incompetence to such a extreme degree that despite long attempts to fall from great heights they were totally unscathed, hid themselves among the Great Pterodactyl's tail scales and hoped the Great One would fly somewhere interesting and life threatening.
And, lo! The Lot of the Lemmings had not been improved one Whit by their Explorations. And so those who has survived the Journey began to multiply further, against such Time as they should be able to continue their Journey.


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Brick by brick we are adding to the legacy of past generations by enhancing the natural beauty, tranquility and spirituality of the Emrich Retreat Center. Nestled on 26 acres in the rural Brighton area, Emrich Retreat Center offers a unique experience for individuals or large groups.
Our Carved in Stone: Grounded in Love Campaign adds a permanent space to memorialize loved ones, celebrate joyous occasions, or to honor family and friends.
Click here to donate a brick paver in honor of a loved one.
D i s c o v e r
A place for spiritual growth...
Discover Nature
Nestled in the rural Brighton area, Emrich Retreat Center offers a unique experience for individuals or large groups. Discover the beauty, tranquility and spirituality of nature as you wander the grounds, engage in prayer or simply bask in the breathtaking wonder of creation. Emrich Retreat Center is a unique place nestled among 5000 acres of State park land. Emrich offers meeting space for small or large groups, complete wedding packages and overnight accomodations for 75 people in five restored historic buildings.
Discover Peace
Emrich offers a rare chance to get away from the pressures and hectic pace of modern life. Accomodations are simple yet comfortable. An onsite caretaker will ensure all of your needs are met, while maintaining your group's privacy.
Discover Community
The spacious, well-tended grounds include two large fire rings, volleyball net, mowed labyrinth, and lots of hiking trails. A large garden provides fresh produce for our kitchen and allws us to give back to those in need in the wider community.
Connected to miles and miles of State trails, including one that take you to Bishop Lake, where you can swim during the summer or cross country ski during the winter.
Discover Spirituality
Our onsite chef provides delicious meals using fresh, local ingredients that can be served buffet style in the dining room or on the covered patio. Meal options ranging from gluten-free to vegan are available.
We know you will fall in love with the beauty and hospitality of Emrich Retreat Center.
Some spots are still available for 2017. Book now for 2018 & 2019!
Call or email today!
The Emrich Retreat Center at Parishfield is owned and operated by the Episcopal Diocese of Michigan.


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To create a LinkedIn post, start on the BOMA dashboard.
Click on the Create button, choose Social Media Update. Name your campaign and click Start.
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Otherwise, add your image and post content. Click Continue.
Choose the channels you want to share this post to.
Click Schedule Delivery and choose when you want to deliver this post.


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Secured my first EXCLUSIVE listing barely a week after announcing that I'm a licensed Real Estate Salesperson or RES they call it. So blessed to have met this down to earth and very nice couple. I like to be very prepared for presentations. Therefore, after consulting my mentor, Adi Mesti Jadi from Synergy Division, I am all set to meet her and her husband. With my calculations ready and mind set on giving an awesome presentation, we met up at their place.
Everyone will remember their FIRST... and this beautiful unit in Jurong West is my FIRST HDB Exclusive Baby!
Owners Yani and Jamal, thank YOU for the opportunity given. I will do my best to market your unit. InShaaAllah. Meanwhile, for those of you interested to look look see see this beautifullllllll unit, do call me ok! Owners are looking to let go at $460K. However, if there is a serious offer, not those kind, action negotiate but actually not interested sort hor! Then owners will consider as they are keen to move out to a new environment. Full parquet flooring and has that rustic resort feeling. You dont have to do much reno if you move in. Plus it's a corner unit and the next door neighbour is quite a distance away. Ni macam kes depan rumah boleh letak meja dan buffet table kalau ada kenduri kendara. Excellent for those who enjoy privacy. Nak tengok rumah ni? Can. Please give me a call and we can arrange it. There are a couple of viewings scheduled for this week already.Thursday, 1 May, 8-9pm and Saturday, 12pm-2pm. :)
Ok. Then a few days later, I met up with yet another home owner who wants to let go of their vacant 5room Punggol flat as their tenancy agreement with their previous tenants has ended. This couple wants to let go of their home to puruse their personal financial plans. This one lagi best. For those of you who wants to be in Punggol but cannot wait for a BTO flat, this is for you. It's in original but well maintained condition. Very good if you want to renovate the whole place from scratch and build it to your dream home. No need to waste money on hacking and tearing down. Super cost saving when it comes to renovation. And, got CONDO view some more! Kalau you berangan satu hari nanti nak tinggal condo, beli rumah ni... pasal bila u tengok hari-hari, manalah tahu satu hari doa you akan terkabul! AMIN!
Owners are willing to let go at $520K. But again, ni semua boleh ajak berbincang.. If you are serious and want to make an offer, owners are willing to negotiate. Tapi janganlah letak harga yang tak masuk akal.. macam nak beli $400K! Rugi lah Sista and Brader! hehe.. Let me know if you are keen!
On top of that, I have a handful of presentations at hand. I've been doing my research and calculations for my potential clients so that they have an idea of what to expect for their sale and purchase transaction. Banyak jugak kes yang dah 55 dan nak jual beli rumah. It's not as simple as that. Ni bukan jual beli barang kat Cash Converter tau! lol. Yes anyone can sell, but are you eligible to buy??? I don't want to be the agent who insist on selling your place when I know you cannot buy. Tak kan nak kasi you duduk dalam khemah tepi pantai sey... Ish. Nauzubillahminzalik!
Can't wait to meet up with these clients and explore more options for them. This is such a fulfilling job lah. Seriously. When clients I meet are happy with my suggestions, I feel a sense of satisfaction. This career is no longer just about making money. It is about educating them with the right knowledge so that they can make better informed decisions.
Then, there are the rental cases. Alhamdulillah, I have quite a few listings now.
1 common room $600 - Jurong West St. 81 Female tenant preferred.
1 common room $650 - Blk 244 Bukit Batok East Ave 5. With wifi, bed, fan. No cooking. 15mins walk to mrt. Female tenant preferred.
1 common room $650 - Blk 849 Tampines St. 83. Low floor. TV, fan, bed, wardrobe provided. Female tenant preferred.
1 common room $650 - Blk 885 Tampines St. 83. High floor. With Air-Con, TV,bed, wardrobe.
1 common room $650 - Blk 244 Bukit Batok East Ave 5. With wifi, bed, fan. No cooking. 15mins walk to mrt. Female tenant preferred.
1 common room $650 - Blk 849 Tampines St. 83. Low floor. TV, fan, bed, wardrobe provided. Female tenant preferred.
1 common room $650 - Blk 885 Tampines St. 83. High floor. With Air-Con, TV,bed, wardrobe.
1 common room $600 - Blk 430 Jurong West Ave 1. Queen bed, study table, wardrobe, fan, light cooking allowed. Punjabi house. Not for fussy tenants.
1 comon room $600 for 1 pax/$800 for 2 pax - Blk Punggol. Bed & fan provided. No TV. Malaysian/Indonesian/Malay/Chinese Females ONLY. No cooking.
1 MASTER Bedroom $1000 (negotiable) - Blk 303 Yishun Central. Level 8. 10 mins walk to MRT & Northpoint Shopping Centre. Near Khoo Teck Puat Hospital. No cooking. Females only. Fan, Queen bed, Cupboard, toilet attached. No wi-fi. Single Malay female owner will be at home.
There you have it. A brief of my experience so far. It has been very challenging but sooooo fulfilling. Alhamdulillah. On top of this, I have been receiving so many enquiries about the career. I'm so glad that i'm able to inspire women out there to step out of our comfort zone and explore real estate. If you are willing to learn, I am willing share. This one I learn from my mentor, Adi and his wife. Adi is so dedicated to the team and is always willing to go all out to share his knowledge and make sure his agents are well equipped before they go out and meet clients. I am blessed lah. Personal property coaching sessions with him are always so enlightening. Ok when I say personal, not just me and him lahhh.. my husband/bodyguard/manager will always be around cos whatever is shared is also relevant to his field of work as a Financial Planner. ;)
Here's us and Adi Mesti Jadi, a TOP Malay agent with ERA. I pun ada pasang cita-cita nak jadi macam dia satu hari nanti.. So successful yet so humble. InShaaAllah. :)
@1030pm - 4am
Who says good things comes easy? Our days are so filled with activities and there is hardly time to breathe. Of course I get tired. But when I see the drive in mentor and his eagerness to share his knowledge, then I get motivated. If he can have a crazy day and still spend time with his recruits, then why not me? So yeah, DEDICATION, PASSION, DRIVE and NEVER-SAY-DIE, that's what it takes to be a great in the industry. I am nowhere near good for now. I am still a baby in Real Estate. However, being new means I am very motivated and willing to work doubly hard to catch up with the achievers.
Nak side track sikit.. At one point in time, my husband's mentor, Encik Zainuden Hashim who has been in the financial planning industry for over 20 years, ever told me to consider putting one foot out of radio to explore my strengths. He believed in me that I have the capacity to soar as a businesswoman. However, I didn't have that much courage to step out of my comfort zone and was very much at ease with my radio job. He is one of those who inspired me to be brave and make that move. So, for that, I must say thank you. Encik Zai has been an awesome mentor to my husband and we are always so blessed for having cross paths with amazing individuals like him.. This is him in action during one of his talks.
(P.S: Ni gambar baru berapa bulan lepas bersalin, jadi macam ada "kembang" sikit. LOL. )
Yup. I'm now Nona, Ejen Rumah. If you put your trust in me for your sale and purchase of your property, I promise to deliver you my best! InShaaAllah. :)
Jadi, tunggu apa lagi? Nak jual atau beli rumah? Nak sewakan rumah atau bilik untuk pendapatan tambahan? telefon lah I... Tak payah nak segan-segan ok! Sila telefon...
9384-0942.. Nona Si Ejen Rumah! lol.
Have a great Tuesday everybodyyyyy!!!!! :)


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Once we were settled we had a great trip. Lots of beach time, it was cold but the kids didn't seem to care, and touring around Maine. We saw amazing light houses and the water smelled so good, it made me miss WA. Actually Maine is a lot like WA. Lots of trees, the beach, and small towns. We ran into some bummers, a lot of things were closed still because the summer season doesn't start until May 1st and we got there the week before. But we made the best of it.
The wedding was perfect. Some light sprinkles but the Boston temple was beautiful and cozy. We had a great time catching up with old friends, most of who live in Arizona but we never seem to see them. But the best part was seeing Justin settled down and happy.
We didn't get to see much of Boston when we went to the wedding but Brandon and I did get to take an adult day trip and left the kids at home later in the week. If it wasn't so cold I think I would have really enjoyed the city. We took a tour bus which was fun, the tour guide provided lots of fun facts and tidbits that added to the experience. I loved history and the piers by the waterfront. Knowing all the events that took place in the city that formed our country, it was an experience everyone should see at least once.
We visited an Amazing farm in Vermont and the Joseph Smith Memorial site. The JSM was incredible. I learned so much about the early church and the prophet. He was an extraordinary man that lived an incredible and trying life. I think the next time I am feeling sorry for myself I will think of him and all the trials he overcame not only from persecution from society and members but everyday trials in his family including losing several children, a major leg injury that had to be surgically repaired with no anesthetic, and investments gone bad.
Despite most of the tourist event being closed for the season we found plenty of museums, play places, and attractions to visit. But I think the kids loved being at the house and hanging with Grandma and Grandpa the most.


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So I say goodbye to 2013.
The Year of… I Don't Know.
That doesn't sound particularly inspiring, does it? It's been a funny old year.
In numbers:
One new job.
One passing of driving test.
Two tattoos.
One wedding of one of my bestest friends.
One international trip.
30 books reviewed on Wear the Old Coat.
Some brilliant posts from my On Writing feature.
One YA novel completely written, edited, polished, sent to CPs (thanks Anna and Rey) and my most respected friends/YA readers (thanks to Sarah, Maggie and Laura).
The other day I was feeling a little blue about the state of my blog this year. 2013 definitely wasn't the year of Wear the Old Coat.
Don't get me wrong, I love reading and writing about YA books but I've come to that stage where I've started focussing more on my own writing. Of course I'll still be reading and reviewing as and when, but don't be alarmed if there's more writing posts in 2014.
As I mentioned before, I completed one YA novel this year. I shelved a project I'd been working on last year because, even though it was fun, it wasn't the story I wanted to have written.
This new story has been an idea that's been knocking around in my head for a while and it took a while to get the words, any words, down on paper… um… I mean computer.
It's a story that's semi-personal, not necessarily to me but it's a subject that's affected me and my life and, inevitably, my writing. It's a contemporary story set in Manchester that tells the story of a couple (that have already got together, longing glances and awkward first conversations and all) and what happens after the happily ever after.
Oh and it's called All This Static (lyrics taken from this song which is not only one of my favourite songs but also very relevant to the story!) I won't go too much into the ins and out but I hope that it's exciting, fresh and, above all, realistic. It may not tick all the boxes of what YA Books Are Officially, but I love what I've written and I stand by it and sometimes it's nice to write something that doesn't fit into every official box.
Of course that doesn't mean I wouldn't change bits if one of my most trusted beta readers was like "Jo, what the hell is THIS?!"
So I probably finished it in about April or so. And in November, I started querying. Proper querying. I made a spreadsheet and everything. OK, I didn't actually keep up with the spreadsheet but the intention was there.
I've had some exciting, high-pitched squeal inducing moments and then some not-so moments and then some great and invaluable feedback. And then, just when I think I should give up and maybe start something else, something further happens and I vibrate on the spot for a few minutes.
At the moment, it's a rolling thing and it's practically impossible to guess what's going to happen next.
But I think I need to remember that there's no rush. I'm more than happy with my writing journey where it is right now because it's new and it's exciting and I'm still learning and with every new project I start, I discover something different about how I write and how other people respond to it.
Last year's writing resolution made me laugh a lot.
Write the story I want to, not the story I think I should be writing. And obviously the usual don't doubt yourself yada yada YOU'RE AWESOME JO yada yada…
I'm going to stick with this one, I think. At this moment, I've written the book I want to write and I'm fairly confident that readers will want to read it. Whenever it gets to that point.
There's no timeline to things like this. It's my dream, yes, but there's no expiration date.
Last year my personal resolutions were:
1. Wear more patterns. – Yep.
2. Drink more water. – (Um… does Diet Coke count?)
3. Stop worrying about things too much. – (So, so)
4. Go on adventures. – (I went whale watching with Flannery, that definitely counts).
This year I have only I have two:
1. Don't scribble things out in your notebook. Besides spelling mistakes, of course, because no one wants to see that. When I find my old writing notebooks, buried amongst books and bank statements and other things, I often cringe when I read them back. I've never written a diary but I imagine that reading through my writing books is the equivalent of reading through your diary you wrote when you were 13. Ouch, right? But even though 95% of it is "Oh my god, I'm never writing again! *fling notebook out of window*" inducing, that 5% could be gold. So I'm going to keep that 5%, just in case.
2. Don't talk yourself out of things because they're not particularly sensible. I'm so bad for doing this. I come up with all these giddy ideas and then think "But, really, can you do that?" At the moment, I'm in the glorious position that yes, I can do that. So I need to just do things without fretting over them. Within reason, of course.
So I've got plans for 2014. Big ideas. I've got travel plans. I've got adventures pending.
And hopefully, hopefully 2014 will be The Year of Something.
Happy New Year everyone!


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Carolina Herrera
Diane von Furstenberg
J. Crew
Jenny Packham
Kate Spade
Lela Rose
Michael Kors
Monique Lhuillier
Oscar de la Renta
Tory Burch
Ralph Lauren
Out of everything I saw in slideshows of New York Fashion Week, I seem to have been drawn in particular to shades of blue, orange, and white, with a bit of grey thrown in for good measure. That I liked so much orange actually surprised me quite a bit, and come spring, I may actually have to consider getting myself something in that color (too bad it will come too late to complete a Thirteen in 2013 goal--that's certainly branching out of my stylistic comfort zone!). I loved the vintage European vibe at so many of the shows too--I think it just adds an extra level of chicness. I'm also loving the natural hair and natural makeup (with bright lips!) seen at so many shows. You can bet I'll be keeping that in mind too once spring rolls around--although I hope it doesn't come too soon. Let's get through autumn and winter, my favorite seasons, first.
What did you like best at #NYFW?
all images via


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All physicians need to become skilled in the performance and interpretation of ultrasound for the care of their patients. What follows are some outstanding YouTube videos on how to perform and interpret bedside ultrasound exam.
The best way to start learning bedside ultrasound is to get access to a scanner and then hire a skilled ultrasound tech to help you learn. This is what I did and it will help you quickly advance your skills at a relatively low cost.
Doing lots of scans on lots of patient models is the way to achieve ultrasound examination competence. Ask all your friends to volunteer. You'll be happily surprised at how soon you achieve competence.
Once you feel competent in performing the scan, you can use an internet over-read service to get immediate diagnostic confirmation of the adequacy of your exam and the correctness of your interpretation until you no longer need it.
You can find an excellent YouTube video on almost any ultrasound scanning technique, case, or problem.
There are a number of great point of care ultrasound books.
But my favorite by far is Essentials of Point-of-Care Ultrasound by Dr. Steve Socransky. This is the book to get started very quickly. Ask the ultrasound tech you hire as your coach to teach to this text as point of care ultrasound scans (POCUS) use different protocols from those used in the ultrasound laboratory.
This book is available for download with iBooks ($14.99) on your Mac or iOS device. Multi-touch books can be read with iBooks on your Mac or iOS device. Books with interactive features may work best on an iOS device. iBooks on your Mac requires OS X 10.9 or later.
When clinicians first began investigating the possibility of using ultrasound themselves, a big secret was concealed from them: image interpretation is easy. The real challenge is image generation: putting the image on the screen. Before The EDE Courses, physicians learned image generation mostly by trial and error. EDE brought a rigorous methodology to the scanning of each area of the body, dramatically reducing the time needed to master this new skill.
What's New in Version 1.3
The 2016 version of Essentials of Point-of-Care Ultrasound includes updates to all chapters. The most significant updates are to the Renal, IVC, and Thoracic chapters. The Renal chapter provides a more incisive way to determine the grade of hydronephrosis. The IVC chapter contains the latest definitions for defining a positive vs negative scan. The Thoracic chapter has an expanded B lines section. A few of the chapters now have a Student's Corner with video mini-lectures of anatomical and pathophysiologic correlations to POCUS. A chapter on Prehospital POCUS has been added.
_______________________________________________________________ Critical Care and Emergency Ultrasound
Dr. Turner is an critical care specialist who has published the following outstanding YouTube videos which are the perfect place to start learning about ultrasound.
Bedside Ultrasound Physics, Knobology and Artifacts, 2013, 23:03, Liz Turner, MD.
eFAST: extended Focused Assessment with Sonography in Trauma, 2013, 17:22, Liz Turner MD.
FATE Exam: Focused Assessed Transthoracic Echo, 2013, 35:41, Liz Turner MD.
Intro Pulmonary Ultrasound, 2013, 36:20, Liz Turner MD.
Advanced Pulmonary Ultrasound, 2013, 24:58, Liz Turner MD.


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Staples has seen that mobile is the future, and is training all of their electronics department employees to push new phone and accessory sales.
Over the last two years, Staples stores have seen a dramatically increased focus on mobile products. Stores saw a huge increase in tablets on the shelves and a new mobile sales associate or two in each store. Last year, the company made the switch away from a third party staffing solution for their mobile sales associates to an in-house position for their Mobility program. Now the company has decided to do away with that position entirely, choosing instead to task their electronics department employees with selling phones and accessories.
Starting in September these employees will not only be trained on the current lineup of AT&T, T-Mobile, and Verizon Wireless devices and plans, but will also be encouraged by a new commission structure to do so.
In a series of documents leaked to Geek.com, we've learned the plan Staples is initiating with the goal of increasing phone sales company-wide. Currently, the Mobility position is a 40-60 hour a week position. This means that either a single full-time employee or a full-time and a part-time employee are the only non-management personnel trained to use the current phone activation systems. By the end of this transition, all electronics department employees will be trained to use a new tool designed to make activation on the three supported networks much easier.
The Mobility position will be absorbed into the electronics department if at all possible, though based on the available documentation the relaunch is only adding 20 hours into the existing electronics pool of hours. This means that if a store is already using all of their electronics department hours, they can only offer 20 hours of work to the currently Mobility employees.
The Mobility relaunch hopes to not only increase the national average of phones sold in each store from the current 4 per week to something much higher, but the company also hopes plans to encourage sales associates to increase the current accessory sales from $17 per activation to $60 per activation. This is fairly common, as the accessories bear the more significant profit for the company. To help encourage these sales, the commission plans now include $35 per new activation and a team wide commission bump for selling more than 200% of the sales goal for phones and a smaller percentage increase for the total number of accessories sold each month.
Staples refocusing on mobile is a significant sign of their intent to compete with Best Buy, who has recently placed significant focus on having companies like Microsoft and Samsung set up specialty shops in their stores to help sell their products. Splitting mobile sales apart from the rest of the store didn't work out for Staples like it did for Best Buy, so the company has shifted their focus to a more global solution in order to better compete moving forward.


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Four baby Whitetip reef sharks were born after a group of shark experts and veterinarians performed the first c-section in SeaWorld history.
The procedure was done on July 18 and each shark weighed less than three pounds at birth.
Wheelchair-Bound Teen Catches 250-pound Shark Off Florida Coast
The park's animal team decided to perform the c-section after noticing a complication with the shark's pregnancy.
A team continues to monitor the baby sharks, which are currently behind the scenes at Discovery Cove, SeaWorld's sister park.
Captain Spots Great White Shark Off Key West
The sharks are doing well and eating and behaving normally, park officials said.


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Superior Water
13230 Evening Creek Dr S # 216
San Diego, CA 92128
(858) 679-2200
(858) 513-0402 (fax)
Superior Water is a family owned and operated company for over 15 years and services residential, commercial and Industrial customers. The Waterboy Whole House Water System continues to be the most recommended water system in southern California. Superior Water prides itself in providing non-chemical water treatment systems for all types of water including wells, pools and more.


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Their stunning wild peregrine falcons are currently sitting on a full clutch of eggs, high up on the cliffside above the Falls of Clyde. From the SWT hide on the opposite cliff visitors can enjoy the closest views of a peregrine eyrie in Britain.
This is the 12th consecutive year of breeding peregrine falcons on the SWT wildlife reserve and they are provided with 24/7 protection.
The SWT Visitor Centre in New Lanark now has direct, live CCTV from the nest site (40 mins walk).
For more info, go to the SWT website.


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Please install Flash® and turn on Javascript.
Stow Austin Studio (formerly Marie Stow Dance Studio) has been established in Auckland's Eastern Suburbs (St Heliers / Kohimarama) for 20 years and has now extended in to the wider Epsom area.
Specialising in Modern Dance with an excellent reputation for being both friendly and professional, the Studio provides classes in a wide range of dance styles including Jazz, Contemporary, Hip Hop, Funk and Dance Exercise for preschool age through to adult.
In addition to an outstanding annual dance production giving all students the " joy of performance" experience in a professional theatre venue, Stow Austin Studio also offers NZAMD examination syllabus from pre grades through to solo seal professional level and IDTA freestyle jazz and cheerleading medal curriculum.
All students are encouraged to reach their personal best in an affirming, vibrant and positive environment, not only having lots of fun but improving their co-ordination, balance, flexibility, musicality, fitness, deportment and self confidence.
All enquiries are most welcome (beginners through to experienced students) and we trust that you will be very happy with our dance programmes and would be delighted to hear from you.
Stow Austin Studio


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Trimethylamine N-oxide
|Trimethylamine N-oxide
trimethylamine oxide
N,N-dimethylmethanamine oxide
Other names
trimethylamine oxide, TMAO, TMANO
|CAS number
|Jmol-3D images
|Image 1
|Molecular formula
|Molar mass
|75.11 g mol−1
|colourless solid
|Melting point
|220–222 °C (hydrate: 96 °C)
|Solubility in water
|Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Trimethylamine N-oxide (TMAO) is the amine oxides with the formula (CH3)3NO. This colorless solid is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine and a common metabolite in animals. It is an osmolyte found in saltwater fish, sharks, rays, molluscs, and crustaceans. It is a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea fishes and crustaceans, where it may counteract the protein-destabilizing effects of pressure.[1] TMAO decomposes to trimethylamine (TMA), which is the main odorant that is characteristic of degrading seafood.
- Synthesis 1
- Trimethylaminuria 2
- Laboratory applications 3
- Health issues 4
- References 5
- See also 6
Treatment of aqueous trimethylamine with hydrogen peroxide affords the dihydrate (Me = CH3):[2]
- H2O2 + Me3N → H2O + Me3NO
Trimethylamine-N-oxide is biosynthesized from trimethylamine, which is derived from choline.[3]
Trimethylaminuria is a defect in the production of the enzyme flavin containing monooxygenase 3 (FMO3).[4][5] Those suffering from trimethylaminuria are unable to convert choline-derived trimethylamine into trimethylamine oxide. Trimethylamine then accumulates and is released in the person's sweat, urine, and breath, giving off a strong fishy odor.
Laboratory applications
Trimethylamine oxide is used in protein folding experiments to counteract the unfolding effects of urea.[6]
In the nucleophilic abstraction, Me3NO is employed as a decarbonylation agent according to the following stoichiometry:
- M(CO)n + Me3NO + L → M(CO)n-1L + Me3N + CO2
This reaction is used to decomplex organic ligands from metals, e.g. from (diene)Fe(CO)3.[2]
It is used in certain oxidation reactions, e.g. the conversion of alkyl iodides to the aldehyde.[7]
Health issues
Studies published in 2013 indicate that high levels of TMAO in the blood are associated with an increased risk of major adverse cardiovascular events.[8] The concentration of TMAO in the blood increases after consuming foods containing carnitine[9] or lecithin[8] if the bacteria that convert those substances to TMAO are present in the gut.[10] High concentrations of carnitine are found in red meat, some energy drinks, and some dietary supplements; lecithin is found in soy, eggs,[10] as an ingredient in processed food and is sold as a dietary supplement. Some types of normal gut bacteria (e.g. species of Acinetobacter) in the human microbiome convert dietary carnitine to TMAO. TMAO alters cholesterol metabolism in the intestines, in the liver, and in artery wall. In the presence of TMAO, there is increased deposition of cholesterol in, and decreased removal of cholesterol from, peripheral cells such as those in the artery wall.[11] Vegan and vegetarian diets appear to select against gut flora that metabolize carnitine (in favor of other gut flora more coordinated with their food supply). This apparent difference in their microbiome is associated with substantially reduced gut bacteria capable of converting carnitine to TMAO.[9][12]
Another source of TMAO is dietary phosphatidylcholine, again by way of bacterial action in the gut. Phosphatidyl choline is present at high concentration in egg yolks and some meats.
It has been suggested that TMAO may be involved in the regulation of arterial blood pressure and aetiology of hypertension.[13]
- ^ Yancey, P. (2005). "Organic osmolytes as compatible, metabolic, and counteracting cytoprotectants in high osmolarity and other stresses".
- ^ a b A. J. Pearson "Trimethylamine N-Oxide" in Encyclopedia of Reagents for Organic Synthesis John Wiley & Sons, 2001: New York. doi:10.1002/047084289X.rt268
- ^ Baker, J.R.; Chaykin, S. (1 April 1962). -oxide"N"The biosynthesis of trimethylamine-.
- ^ Treacy, E.P.; Akerman, BR et al. (1998). "Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication". Human Molecular Genetics 7 (5): 839–45.
- ^ Zschocke J, Kohlmueller D, Quak E, Meissner T, Hoffmann GF, Mayatepek E (1999). "Mild trimethylaminuria caused by common variants in FMO3 gene". Lancet 354 (9181): 834–5.
- ^ Zou, Q. et al. (2002). "The Molecular Mechanism of Stabilization of Proteins by TMAO and Its Ability to Counteract the Effects of Urea".
- ^ Volker Franzen (1973), "Octanal",
- ^ a b Tang, W.H. Wilson; Zeneng Wang; Bruce S. Levison; Robert A. Koeth; Earl B. Britt; Xiaoming Fu; Yuping Wu; Stanley L. Hazen (April 25, 2013). "Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk". The New England Journal of Medicine 368 (17): 1575–1584.
- ^ a b Koeth, Robert A; Zeneng Wang, Bruce S Levison, Jennifer A Buffa, Elin Org, Brendan T Sheehy, Earl B Britt, Xiaoming Fu, Yuping Wu, Lin Li, Jonathan D Smith, Joseph A DiDonato, Jun Chen, Hongzhe Li, Gary D Wu, James D Lewis, Manya Warrier, J Mark Brown, Ronald M Krauss, W H Wilson Tang, Frederic D Bushman, Aldons J Lusis & Stanley L Hazen (Published online April 7, 2013). "Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis". Nature Medicine 19 (5): 576–85.
- ^ a b Gina Kolata (April 24, 2013). "Eggs, Too, May Provoke Bacteria to Raise Heart Risk". The New York Times. Retrieved April 25, 2013.
- ^ Hazen, Stanley. "New Research On Red Meat And Heart Disease". The Diane Rehm Show (Transcript). WAMU 88.5 American University Radio. Retrieved 10 April 2013.
- ^
- ^ http://www.onlinecjc.ca/article/S0828-282X%2814%2901363-4/abstract