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فهرست مطالب
- Volume:10 Issue: 5, 2019
- تاریخ انتشار: 1398/06/10
- تعداد عناوین: 12
Brain Connectivity Reflected in Electroencephalogram Coherence in Individuals With Autism: A Meta-analysisPages 409-418Introduction
Many theories have been proposed about the etiology of autism. One is related to brain connectivity in patients with autism. Several studies have reported brain connectivity changes in autism disease. This study was performed on Electroencephalogram (EEG) studies that evaluated patients with autism, using functional brain connectivity, and compared them with typically-developing individuals.Methods
Three scientific databases of ScienceDirect, Medline (PubMed), and BioMed Central were systematically searched through their online search engines. Comprehensive Meta-analysis software analyzed the obtained data.Results
The systematic search led to 10 papers, in which EEG coherence was used to obtain the brain connectivity of people with autism. To determine the effect size, Cohen's d parameter was used. In the first meta-analysis, the study of the maximum effect size was considered, and all significant effect sizes were evaluated in the second meta-analysis. The effect size was assessed using a random-effects model in both meta-analyses. The results of the first meta-analysis indicated that heterogeneity was not present among the studies (Q=13.345, P>0.1). The evaluation of all effect sizes in the second meta-analysis showed a significant lack of homogeneity among the studies (Q=56.984, P=0.0001).Conclusion
On the whole, autism was found to be related to neural connectivity, and the present research showed the difference in the EEG coherence of people with autism and healthy people. These conclusions require further studies with more extensive data, considering different brain regions, and novel analysis techniques for assessing brain connectivity.Keywords: Autism spectrum disorder, Electroencephalography, Coherence, Meta-analysis
Pages 419-432Introduction
The present systematic review and meta-analysis aims to investigate the role of Posterior Tibial Nerve Stimulation (PTNS) in the control of fecal incontinence (FI).Methods
Two independent reviewers extensively searched in the electronic databases of Medline, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, CINAHL, and Scopus for the studies published until the end of 2016. Only randomized clinical trials were included. The studied outcomes included FI episodes, FI score, resting pressure, squeezing pressure, and maximum tolerable pressure. The data were reported as Standardized Mean Differences (SMD) with 95% confidence interval.Results
Five articles were included in the present study (249 patients under treatment with PTNS and 239 in the sham group). Analyses showed that PTNS led to a significant decrease in the number of FI episodes (SMD=-0.38; 95% CI: -0.67-0.10; P=0.009). Yet, it did not have an effect on FI score (SMD=0.13; 95% CI: -0.49-0.75; P=0.68), resting pressure (SMD=0.12; 95% CI: -0.14-0.37; P=0.67), squeezing pressure (SMD=-0.27; 95% CI: -1.03-0.50; P=0.50), and maximum tolerable pressure (SMD=-0.10; 95% CI: -0.40-0.24; P=0.52).Conclusion
Based on the results, it seems that the prescription of PTNS alone cannot significantly improve FI.Keywords: Fecal incontinence, Tibial nerve, Electrical nerve stimulation, Tibial neuromodulation
Bumetanide Therapeutic Effect in Children and Adolescents With Autism Spectrum Disorder: A Review StudyPages 433-442Introduction
Autism Spectrum Disorder (ASD) is characterized by several impairments in communications and social interactions, as well as restricted interests or stereotyped behaviors. Interventions applied for this disorder are based on multi-modal approaches, including pharmacotherapy. No definitive cure or medication has been introduced so far; therefore, researchers still investigate potential drugs for treating ASD. One of the new medications introduced for this purpose is bumetanide. The present article aimed to review the efficacy of this drug on the core symptoms of ASD and its potential side effects.Methods
We searched all papers reported on pharmacokinetics, pharmacodynamics, efficacy, and adverse effects of bumetanide on animal models and humans with ASD. The papers were extracted from the main databases of PubMed, Web of Science, and Scopus.Results
The findings revealed that cortical neurons have high chloride ion (Cl−)i and excitatory actions of gamma-aminobutyric acid in the valproic acid animal model with ASD and mice with fragile X syndrome. Bumetanide, which has been introduced as a diuretic, is also a high-affinity-specific Na+-K+-Cl− cotransporter (NKCC1) antagonist that can reduce Cl− level. The results also indicate that bumetanide can attenuate behavioral features of autism in both animal and human models. Moreover, the studies showed that such medication could activate fusiform face area in individuals with ASD while viewing emotional faces. Also, recent findings suggest that a dose of 1 mg/d of this drug, taken twice daily, might be the best compromise between safety and efficacy.Conclusion
Recent studies provided some evidence that bumetanide can be a novel pharmacological agent in treating core symptoms of ASD. Future studies are required to confirm the efficacy of this medication in individuals with ASD.Keywords: Bumetanide, Diuretics, Autism Spectrum Disorder (ASD)
Pages 443-450
One of the interesting topics in neuroscience is problem solving and decision-making. In this area, everything gets more complicated when events occur sequentially. One of the practical methods for handling the complexity of brain function is to create an empirical model. Model Predictive Control (MPC) is known as a powerful mathematical-based tool often used in industrial environments. We proposed an MPC and its algorithm as a part of the functionalities of the brain to improve the performance of the decision-making process. It is well known that the decision-making process results from communication between the prefrontal cortex (working memory) and hippocampus (long-term memory). However, there are other regions of the brain that play essential roles in making decisions, but their exact mechanisms of action still are unknown. In this study, we modeled those mechanisms with MPC. We showed that MPC controls the stream of data between prefrontal cortex and hippocampus in a closed-loop system to correct actions.Keywords: Decision-making process, Model predictive control, Memory structure, Prefrontal cortex, Hippocampus
Protective Effects of Nucleobinding-2 After Cerebral Ischemia Via Modulating Bcl-2/Bax Ratio and Reducing Glial Fibrillary Acid Protein ExpressionPages 451-460Introduction
Nucleobinding-2 (NUCB2) or nesfatin-1, a newly identified anorexigenic peptide, has antioxidant, anti-inflammatory, and anti-apoptotic properties. Brain ischemia-reperfusion induces irreversible damages, especially in the hippocampus area. However, the therapeutic effects of NUCB2 have not been well investigated in cerebral ischemia. This study was designed for the first time to investigate the protective effects of NUCB2/Nesfatin-1 on the expression of apoptosis-related proteins and reactive astrogliosis level in the CA1 area of hippocampus in an experimental model of transient global cerebral ischemia.Methods
The male Wistar rats were randomly allocated into 4 groups (sham, NUCB2, ischemia-reperfusion, and ischemia-reperfusion+NUCB21) (n =7). The model of cerebral ischemia was prepared by common carotid arteries occlusion for 20 minutes. Nesfatin-1 (20 µg/kg) and saline (as a vehicle) were injected (intraperitoneally) at the beginning of the reperfusion period. The assessment of the protein expression levels was performed by immunofluorescence and immunohistochemical staining.Results
NUCB2 significantly reduced the Bax and GFAP protein levels in the CA1 area after ischemia (P<0.05). Also, NUCB2 increased Bcl-2 protein level (P<0.05). NUCB2 exerted protective effects against ischemic injury by the inhibition of astrocytes activation as an inflammatory response and decreased neuronal cell apoptosis.Conclusion
The present study provides the possible neuroprotective view of nesfatin-1 in the treatment of ischemia injury model in rat hippocampus.Keywords: Nucleobinding-2 (NUCB2), Nesfatin-1, Apoptosis, Astrogliosis, Hippocampus, Ischemia
Spatial Learning and Memory in Barnes Maze Test and Synaptic Potentiation in Schaffer Collateral-CA1 Synapses of Dorsal Hippocampus in Freely Moving RatsPages 461-468Introduction
Synaptic plasticity has been suggested as the primary physiological mechanism underlying memory formation. Many experimental approaches have been used to investigate whether the mechanisms underlying Long-Term Potentiation (LTP) are activated during learning. Nevertheless, little evidence states that hippocampal-dependent learning triggers synaptic plasticity. In this study, we investigated if learning and memory in the Barnes maze test are accompanied by the occurrence of LTP in Schaffer collateral to CA1 synapses in freely moving rats.Methods
The rats were implanted with a recording electrode in stratum radiatum and stimulating electrodes in Schaffer collaterals of the CA1 region in the dorsal hippocampus of the right hemisphere. Following the recovery period of at least 10 days, field potentials were recorded in freely moving animals before and after training them in Barnes maze as a hippocampal-dependent spatial learning and memory test. The slope of extracellular field Excitatory Postsynaptic Potentials (fEPSPs) was measured before and after the Barnes maze test.Results
The results showed that the fEPSP slope did not change after learning and memory in the Barnes maze test, and this spatial learning did not result in a change in synaptic potentiation in the CA1 region of the hippocampus.Conclusion
Spatial learning and memory in the Barnes maze test are not accompanied by LTP induction in Schaffer collateral-CA1 synapses.Keywords: Synaptic plasticity, Hippocampus, Barnes maze test, Spatial memory
Pages 469-474Introduction
The current study aims to measure the validity, reliability, and psychometric properties of the Persian translation of the Video Gaming Addiction Test (VAT).Methods
A total of 280 young men (14-20 years old) (Mean±SD age: 17.22±1.8 years), including excessive gamers and normal subjects, entered the study. They answered VAT, Visual Analog Scale (VAS), and Conner-Davidson Resilience Scale (CD-RISC). The VAT was translated and then back-translated. For testing reliability, we used the Cronbach alpha, split-half method, and Guttman method. Also, convergent and discriminant validity were tested to examine the construct validity of the translated version of VAT.Results
The Cronbach alpha for the total scale was 0.81. Also, after splitting questions in half, the Cronbach alpha values for these halves were 0.71 and 0.69. Six Guttman lambdas were calculated with 0.75 minimum and 0.82 maximum, all showing good reliability of the test. Convergent validity was tested by testing the correlation between VAT and VAS. The Pearson correlation was fond 0.73, showing a strong relationship between the two factors (P<0.001). For testing discriminant validity, the association of VAT with CD-RISC was tested, showing no correlation between these scales (r=-0.157; P=0.09).Conclusion
The Persian translation of the VAT is valid and reliable, and it is appropriate for research and clinical use with acceptable properties, similar to the original version.Keywords: Video gaming Addiction test, Reliability, Validity, Psychometric properties
Neuropsychological Decomposing Stroop Interference Into Different Cognitive Monitoring: An Exploratory Factor AnalysisPages 475-484Introduction
There are two alternative explanations of the Stroop phenomenon. Several studies have revealed that the difference in performance on congruent and incongruent trials can arise from response interference. On the contrary, many authors have claimed that Stroop interference might occur at earlier processing stages related to semantic or conceptual encoding. The present study aims to determine the number and nature of the factors necessary to account for the multiple components of Stroop interference.Methods
The sample consisted of 247 undergraduate and postgraduate students. We employed the computerized version of the Stroop task adapted to the Iranian population. An exploratory principal components analysis was conducted on the correlations of 6 variables (reaction time under congruent and incongruent conditions, omission error under congruent and incongruent conditions, and commission error under congruent and incongruent conditions).Results
Two factors were extracted. The first factor may be semantic interference, and the second factor may be response interference.Conclusion
The findings of this research are consistent with the multiple-stage account, claiming that Stroop interference is because of both semantic and response interferences.Keywords: Stroop, Stroop interference, Semantic interference, Response interference
A 6-step Approach to Gain Higher Quality Results From Organotypic Hippocampal Brain Slices in a Traumatic Brain Injury ModelPages 485-496Introduction
Organotypic Hippocampal Brain Slices (OHBS) provide a better alternative to in vivo models to scrutinize Traumatic Brain Injury (TBI). We followed a well-established TBI protocol but noticed that several factors might influence the results in such a set-up. Here, we describe a structured approach to generate more comparable results and discuss why specific eligibility criteria should be applied.Methods
We defined necessary checkpoints and developed inclusion and exclusion criteria that took into consideration the observed variation in such a model. Objective measures include the identification and exclusion of pre-damaged slices and outliers. In this study, six steps were outlined.Results
A six-step approach to enhance comparability is proposed and summarized in a flowchart. We applied the suggested measures to data derived from our TBI-experiments, examining the impact of three different interventions in 1459 OHBS. Our exemplary results show that more precise findings are ensured through equal requirements set for all slices.Conclusion
Results in a TBI experiment on OHBS should be critically analyzed as inhomogeneity may occur. In other words, a structured approach to comparing the results should be followed to ensure achieving more precise findings. Further research is recommended to confirm and further develop this framework.Keywords: Organotypic hippocampal brain slices, In vitro model, Traumatic Brain Injury (TBI), Propidium Iodide (PI), Eligibility, Framework
Correlation Analysis of the Tinnitus Handicap Inventory and Distress Network in Chronic Tinnitus: An EEG StudyPages 499-514Introduction
Tinnitus is a common disorder with a considerable amount of distress that affects the patient`s daily life. No objective tools were approved for measuring tinnitus distress. It can be estimated only by subjective scales and questionnaires, albeit, the Electroencephalography (EEG) studies have reported some alterations regarding tinnitus distress network. This study aimed to investigate the correlation between Tinnitus Handicap Inventory (THI) and the recorded EEG data.Methods
A total of 33 chronic tinnitus cases (9 females) with the mean age of 42.67 years were recruited. Their THI scores were collected, and a 3-minute EEG recorded with eye closed at resting-state. The correlation analysis was performed on THI scores and the current density in the selected Region of Interests (ROIs) concerning the distress network for the eight frequency bands. The patients grouped depending on the THI cutoff point of 56 into low and high THI groups, and then the groups were compared for source analysis and functional connectivity between ROIs using standardized low-resolution brain electromagnetic tomography.Results
A significant positive correlation was seen between THI scores and the electrical activity in the Anterior Cingulate Cortex (ACC), the prefrontal cortex, and the parahippocampus for an alpha band (P<0.05) and in the ACC for beta (P<0.01). Source analysis showed significant differences with increased activity in the high THI group for alpha, beta and gamma bands. Functional connectivity was also elevated in the high THI group between the ROIs in alpha and beta bands.Conclusion
THI can be a useful tool for measuring tinnitus distress, and it has a high correlation with EEG data.Keywords: Tinnitus, Tinnitus-related distress, Tinnitus Handicap Inventory (THI), Correlation, Electroencephalography, Functional connectivity
Pages 515-526Introduction
Noise is an environmental stressor and can cause or exacerbate mental disorders, and affect the individual performance in certain conditions. This study aimed to evaluate the combined effects of noise and smoking on the cognitive performance of the workers in the automotive industry.Methods
This research is a descriptive-analytical study with a cross-sectional design conducted on 300 workers randomly assigned into two groups of noise-exposed and nonexposed. They were examined using computerized tests, including the Tower of London test (TOL), Continuous Performance test (CPT), and Stroop test. The sound pressure levels were measured based on an 8-hour equal-loudness contour in each group according to ISO 9612 standard, using the Testo CEL-815 sound level meter.Results
The study of combined effects of noise and smoking on 12 CPT indicators using the 2-way Analysis of Variance (ANOVA) indicate that noise and smoking factors had a significant impact on the mean number of errors and correct responses in the third 50-stimuli stage, the mean number of errors and correct responses in the second 50-stimuli stage with P<0.001, P<0.001, P=0.012 and P<0.001 for smoking respectively, but only noise affected the other 7 indicators (P<0.001).Conclusion
Smoking and noise have negative impacts on concentration, attention, and cognitive processing speed, which can lead to an individual's mistakes and delayed decision making at the workplace.Keywords: Stroop test, Smoking, Noise, Occupational, Cognitive science
Curcumin Effects on Memory Impairment and Restoration of Irregular Neuronal Distribution in the Hippocampal CA1 Region After Global Cerebral Ischemia in Male RatsPages 527-540Introduction
Global Cerebral Ischemia (GCI) causes neuronal damage with subsequent neurological and cognitive impairments. Curcumin has anti-inflammatory, antioxidant, and neuroprotective properties, which makes it a potential candidate for improving GCI-induced impairments. This study aimed to investigate the effects of curcumin on the neurological and memory deficits, as well as spatial neuronal distribution in the CA1 region after GCI in rats.Methods
56 Sprague-Dawley male rats were randomly assigned into 4 groups of sham (n=14), control (n=14), curcumin 50 mg/kg (n=14), and curcumin 100 mg/kg (n=14). Each group was divided into the two subgroups of short-term (7 days) and long-term (28 days) treatment periods. The neurological severity score (NSS), passive avoidance task, and the traction test were performed at postoperative days of 0, 1, 2, 3, 7, 14, 21, and 28. The novel object recognition test and Voronoi tessellation were carried out on days 7 and 28 after GCI.Results
Curcumin 100 mg/kg significantly decreased neurological severity score on postoperative days of 7 and 28 compared with the control (P<0.001) and curcumin 50 mg/kg groups (P<0.05-P<0.001). Also, curcumin 100 mg/kg significantly increased step-through latency times on postoperative days of 3-28 and 14-28 compared with the control (P<0.05-P<0.001) and curcumin 50 mg/kg groups (P<0.01-P<0.001). Moreover, it increased the novelty preference index during the novel object recognition test in the 28-day treatment subgroup after GCI. Curcumin (100 mg/kg) could maintain the neuronal aggregation in the CA1 region after GCI at a level near to what is generally observed in normal rats.Conclusion
Curcumin could improve memory and neurological deficits and restore irregular neuronal distribution in the CA1 region after GCI in a time-dependent manner, and its higher dose was more effective than its lower dose. Curcumin may have beneficial effects on reducing brain complications after ischemia.Keywords: Curcumin, Global cerebral ischemia, Memory, Neurological deficit, Tessellation, Brain, Rat


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Inside the Market's roundup of some of today's key analyst actions
Desjardins Securities analyst Maher Yaghi thinks the attempts by Corus Entertainment Inc.'s (CJR.B-T) management to improve its financial position will prove unsuccessful.
In the wake of Wednesday's third-quarter financial results, which were overshadowed by a 79-per-cent cut to its annual dividend (to 24 cents from $1.14) and sent the stock plunging 17.9 per cent to a record low, Mr. Yaghi said he expects Corus' top line to continue to decline over "many" years.
"While the [dividend] cut was anticipated, it was at the high end of our 50–75-per-cent expectation," he said. "The stock now yields 4.7 per cent annually, which is still higher than the peer average. We believe that reducing the dividend is the right way forward given CJR's elevated debt, but the high dividend was without a doubt a reason to own the stock. In addition, the company took a $1.0-billion asset writedown as the challenging environment reduces the value of goodwill and licences. To value these assets, management is now using a TV earnings growth rate of a decline 7.4 per cent to an increase of 0.3 per cent and a terminal growth rate of 0–1 per cent. Management also provided additional details on its strategy.
"While CJR is working to increase monetization of its assets, we believe the lack of significant control over content and delivery methods is likely to steadily erode revenue."
In reaction to the results, Mr. Yaghi lowered his revenue forecast for Corus in order to "reflect the current advertising environment as well as the company's assumptions included in the goodwill review."
He added: "We have also reduced the medium-term growth rate in our DCF [discounted cash flow] to a decline of 4 per cent (from a 2-per-cent drop) for the same reasons. Even though the company exceeded our margin expectations in the quarter, we have made little change to our margin forecast as continued cost-control efforts should be offset by the declining top line, which reduces potential economies of scale. Following these adjustments, we now forecast EBITDA will decline by 2.5 per cent in FY18 and 4.9 per cent in FY19."
Maintaining a "hold" rating for Corus shares, Mr. Yaghi dropped his target price to $6.50 from $9.50. The average target on the Street is currently $6.28, according to Bloomberg data.
"We believe there is elevated risk related to owning CJR shares," he said. "While the company still generates healthy cash flows, we believe the TV environment will be challenging for the foreseeable future. We believe that a sustainable stabilization of advertising revenue is key for investors to gain confidence in future outperformance from CJR."
Elsewhere, National Bank Financial analyst Adam Shine upgraded Corus to "sector perform" from "underperform" with a target of $5.50 (unchanged).
A pair of equity analysts upgraded Detour Gold Corp. (DGC-T) on Thursday in response to Wednesday's release of an updated life of mine plan for its Detour Lake operation located in northeastern Ontario.
Eight Capital analyst Craig Stanley moved Detour shares to "buy" from "neutral" after the results fell in line with his expectation following preliminary results in late April.
Citing lower-than-anticipated capex expectations, Mr. Stanley said his free cash flow forecast at spot prices in 2018-2020 increased to $100-million from $72-million.
He did lower his target for Detour shares to $14.80 from $15.20, noting marginally higher operating costs have reduced cash flow per share estimate over the next two years.
Scotia Capital analyst Trevor Turnbull raised his rating to "sector outperform" from "sector perform" despite calling the LOM plan is non-event as guidance was largely unchanged.
"Many, including potential acquirers of the company, could not care less," said Mr. Turnbull, who believes the company is a desirable asset for buyers.
Seeing the stock trading at a significant discount to its valuation due to uncertainty and erosion in confidence, he hiked his target to $18 from $15. The average target on the Street is $16.29.
After its fourth-quarter earnings fell "well below" the Street's expectations, AltaCorp Capital analyst Keith Carpenter downgraded Canopy Growth Corp. (WEED-T) to "sector perform" from "speculative buy," citing its current valuation.
"The Company is well positioned to benefit from the opening of the Canadian recreational market and the advancement of the international medicinal market," he said. "Their size, capacity, inventory levels, and platform all provide the basis in which to grow their business and strengthen their market share. However, one of the issues the Company will have to prove out to investors post the launch of the recreational market is whether they will be efficient with regards to their costs. We accept that management needs to build out its platform and there is a ramp in costs associated with that. However, having never gone through this process in this sector at this level, it's also difficult for management to pinpoint that the substantial ramp that is occurring in SG&A costs will not overshoot and impact those expanded sales later this year and going forward. As a result, we remain cautious of the Company's cost efficiency potential over the next few years."
Mr. Carpenter lowered his target by a loonie to $40. The average target on the Street is $36.06.
Russel Metals Inc. (RUS-T) presents a "balanced risk-reward investment opportunity," according to RBC Dominion Securities analyst Derek Spronck, believing it is benefitting from both higher steel prices and steady end-market demand.
Though he cautions that the potential indirect impact of steel tariffs creates "some near-term uncertainty" and he sees better upside opportunities elsewhere in his coverage universe over the next 12 months, Mr. Spronck initiated coverage of the Mississauga-based company with a "sector perform" rating.
"Russel Metals is a top-ten steel and steel product distributor in North America by way of revenue," he said. "The key is that as steel prices move directionally, so has the opportunity in the shares of RUS - with revenue, EPS, and share price performance exhibiting high correlations (60 per cent or more) to steel prices. However, with steel prices up more than 50 per cent year over year, and with steel price futures pointing to softer prices in 2019, we see less earnings and valuation upside in shares of RUS in the near-term."
"Russel primarily sources U.S. steel for its U.S. operations (and vice-versa in Canada). Tariffs add to the price of steel and higher prices are generally a positive for Russel. Where there is some uncertainty is whether Russel will be able to pass on the full tariff increase to customers (where impacted). There could also be indirect consequences of tariffs (and increasing trade protectionism) that could result in lower economic growth – which would be a negative. We do think tariffs will be a net neutral impact for Russel, consistent with management's views. However, it does create some uncertainty, with potential countermeasures that could still further influence the market."
Mr. Spronck set a target price for Russel Metals shares of $30. The average target is $34.75.
"Russel Metals offers investors: 1) cyclical exposure by way of end-market demand for steel products; 2) strong anticipated ROE [return on equity] generation of 16 per cent; and 3) a dividend yielding 5 per cent that is partial protected due to the counter-cyclicality of cash flows," the analyst said. "We do see valuations as fair given the context of the current and anticipated operating environment. However, for investors looking for dividend yield and/or with a more positive view around GDP/steel pricing, we think shares of RUS would be an appropriate investment in that context."
CIBC World Markets analyst Mark Jarvi initiated coverage of both Canadian Utilities Ltd. (CU-T) and Atco Ltd. (ACO-X) with "neutral" ratings.
"We believe valuations have become more attractive as these stocks and the broader sector have come under pressure due to rising rates and a rotation out of defensive, interest rate-sensitive stocks," said Mr. Jarvi. "While we do foresee potential upside (through higher earnings), we have a cautious stance on these stocks given our views on near-term earnings contraction, slowing growth, geographic/regulatory concentration and a more complicated structure with insider voting control."
Mr. Jarvi gave Canadian Utilities a $34 target, which sits below the consensus of $37.61.
"Canadian Utilities has delivered very strong results over the last several years, but we now expect growth on all fronts to slow for a few reasons: rate base growth in its core Alberta market has moderated, utility ROEs are expected to decline albeit we still expect over-earnings vs. the deemed ROE, and the outlook for the unregulated businesses is generally more muted," he said. "With slowing earnings and cash flow growth, and little room to raise the payout ratio, we believe dividend growth will moderate. However, we believe the company will continue to with its impressive track record of 46 years of consecutive dividend increases. The balance sheet remains in good shape and potential acquisitions or new unregulated investments could provide upside to our forecast and could improve the company's diversification."
His target for Atco is $42, which is 42 cents below the consensus.
"ATCO Ltd. provides investors with exposure to predominately stable regulated earnings through its 52.5-per-cent ownership of Canadian Utilities and also has potential upside from unregulated assets including the Structure & Logistics business," said the analyst. "The unregulated businesses have seen earnings declines over the past few years — we believe operations have stabilized, thanks to improved cost savings and efficiencies, and acknowledge that potential increased economic activity in Alberta and/or the resource sector could drive a material uplift in earnings. In terms of the regulated utility operations, we believe earnings growth is slowing due an expected reduction in earned ROEs and lower rate base growth. The lower earnings growth should likely translate to lower dividend growth—while the trailing five-year CAGR for dividends is 15 per cent, we believe the growth will drop below 10 per cent. While relative valuation is cheaper than utility peers, a discount is warranted given its structure (i.e. holdco discount) and the volatility of the unregulated operations."
In the wake of Wednesday's release of "mixed" second-quarter financial results, Desjardins Securities analyst Gary Ho called AGF Management Ltd. (AGF.B-T) a "value play."
"It remains our preferred name in the sector given its attractive valuation (4.0 times our estimated 2019 wealth management EBITDA; we value the S&W [Smith & Williamson] stake at a conservative $267-million), net sales turnaround (in both retail and institutional), improving management credibility and the S&W jewel which potentially provides upside to our $8.50 target price," he said.
The Toronto-based asset management firm reported adjusted earnings per share of 14 cents, excluding a 12-cent gain from a transfer pricing provision release and 5-cent loss stemming from restructuring. Both Mr. Ho and the Street had projected a 15-cent profit. Adjusted wealth management EBITDA of $16.8-million also missed the analyst's expectation ($18.4-million), which he attributed to higher-than-anticipated expenses from a marketing push.
With the results, Mr. Ho lowered his fiscal 2018 EBITDA estimate to $66.2-million from $73.4-million, but he increased his earnings per share projection by 5 cents to 77 cents.
He kept a "buy" rating and $8.50 target for the stock, which is slightly above the consensus of $8.36.
"We foresee a few near- or medium-term positive catalysts: (1) improving fund performance leading to 60 per cent of AUM [assets under management] above median over three years; (2) net retail flows improving relative to industry; (3) investors recognizing a proper valuation of S&W; (4) restoring management's credibility; and (5) all of these factors leading to better sentiment and valuation," said Mr. Ho.
Stuart Olson Inc. (SOX-T) now sits on "solid footing," according to Raymond James analyst Frederic Bastien, who believes Calgary-based construction services company is finally making in-roads into Ontario.
"It's taken some time for CEO David LeMay and his team to tap Canada's largest construction market, but his persistence is paying off," said Mr. Bastien in a research note following recent sessions with management in Vancouver.
"Today, all three Stuart Olson divisions have something going for them in the province. The Industrial Group just wrapped up a new wet gas cleaning plant for Vale in Sudbury while the Buildings Group has been successful executing various jobs for large post-secondary institutions (which buy into the construction management approach SOX embraces). The Commercial Group is arguably having even better traction, with the who's who in Canadian general construction and the budding marijuana grow-op segment increasingly turning to Canem for its unparalleled control systems expertise. Based on this broad momentum, it isn't far-fetched to think Ontario can become Stuart Olson's largest market at some point in time."
Also citing "improving prospects for industrial work and prudent capital allocation yielding solid returns for its shareholders over the foreseeable future," Mr. Bastien raised his target price for Stuart Olson shares to $9 from $8 with an "outperform" rating (unchanged). The average is $8.42.
Square Inc. (SQ-NQ) remains a "marquee 'risk-on' momentum stock," according to Citi analyst Peter Christiansen, who expects its performance to remain volatile.
"SQ's recent momentum has been impressive, and we recognize the long-term opportunity has likely been validated with PayPal's acquisition of iZettle and First Data's bullish emphasis on Clover," the analyst said. "We do believe the opportunity for micro/SMB Cloud-based POS remains large, though we sense Square's competition will begin to intensify, particularly as it continues to push upmarket. Distribution will be key, and Square does not have the luxury of bank/issuer partnerships or an untapped base of merchants to leverage. Still, we view Square's offering to be compelling and consider the firm as a category leader in a segment undergoing significant innovation and strong secular growth. For now we remain Neutral, as we look to gain better comfort/evidence of Square's upmarket competitiveness and/or see the stock at a more attractive level — SQ's multiples rank greater-than 95 percentile of more than 2,000 stocks, indicating less than attractive risk/reward."
Expecting the company's subscriptions and services segment to achieve a compound annual growth rate of 60 per cent over the next 2 years and "outsized" growth from Instant Deposit option and Caviar food delivery service, Mr. Christiansen raised his target to US$67 from US$47. The average is US$56.89.
"We think continued execution and expectations beating for the next 2–3 quarters presents support for at least modest appreciation from current levels," he said.
"We await a more attractive Risk/Reward setup before getting more aggressive on the name."
In other analyst actions:
TD Securities analyst Damir Gunja downgraded Great Canadian Gaming Corp. (GC-T) to "hold" from "buy" with a target of $51, falling from $54 and lower than the consensus of $53.70.
Canaccord Genuity analyst Raveel Afzaal downgraded Crius Energy Trust (KWH.UN-T) to "hold" from "buy" with a target of $7.50, down from $9 and under the consensus of $9.90.
Cormark Securities analyst Jason Zhang reinstated coverage of Horizon North Logistics Inc. (HNL-T) with a "buy" rating and $3.25 target (from $2.80). The average is $3.40.
Scotia Capital analyst Michael Doumet downgraded Ritchie Bros. Auctioneers Inc. (RBA-N, RBA-T) to "sector perform" from "outperform" with a US$37 target. The average is US$33.09.

subset: commoncrawl


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The Compassionate Conservative: Assuming Responsibility and Respecting Human Dignity
The Compassionate Conservative: Assuming Responsibility and Respecting Human Dignity
After half a century of watching the proliferation of government programs, the American people are questioning whether government truly has, as liberal politicians claim, the wherewithal to provide the cure for society's ills. That questioning has afforded conservatives a prime opportunity to dispel a myth that has been perpetrated across the national political spectrum for decades: the myth that liberal political policy is inherently more compassionate and altruistic than conservative social and economic policy.
The purveyors of that myth have taken advantage of a common presupposition that cultural values are somehow antithetical to economic achievement. This opposition is, in fact, quite false. Democratic capitalism has been history's best weapon against poverty, oppression, and tyranny. Free markets have generated an environment in which an unrivaled number of men and women have been able to attain for themselves an unparalleled standard of living. As economist Joseph Schumpeter once observed, "The capitalists' achievement does not consist in providing silk stockings for queens, but in bringing them within reach of factory girls."
Compassion administered through the state on the other hand, though it may provide basic needs to many, can eventually . . .


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In Chinese, it's called "Xian Qi" which is a mix of dislike, avoid,refusal and disdain. It is usually used by people in the position of power or those who have advantage over others.
For real, man? Used on or used by? In English, it's more in the intonation, rather than the words in these situations. – Lambie Nov 4 '19 at 20:24
1You are on the wrong site. This is not a Chinese-English translation site. Please read the Tour. – David Nov 4 '19 at 20:31
Now I am confused. I said "used on "because I'm thinking as an author, as I am using this word on someone to describe the expression. – Rob F Nov 4 '19 at 20:33
David, it's not a translation question. I know how to translate it, but I just need to find a better word that match the meaning perfectly. – Rob F Nov 4 '19 at 20:35
1You could choose or look up synonyms for 'dismissive'. But I'd go with 'disdain/ful', which you suggest. – Edwin Ashworth Nov 5 '19 at 13:55
The person on the left has a sneer (noun) or is sneering (verb).
(verb) 1 : to smile or laugh with facial contortions that express scorn or contempt
(noun) : the act of sneering
Visual depictions of the expression will vary. Usually the nose or brow is engaged in a sneer, with one or both sides of the face drawn upward in a way that shouldn't be mistaken for a smile. The Body Language Project, a collection of nonverbal gestures and descriptions, features a mostly symmetrical sneer:
Sneering happens quickly, often in a split second, when the muscles between the eyes just above the nose contract forcing the skin around the nose to wrinkle and the brows to furrow. Sneers activate the buccinator muscles located on the sides of the face to draw the corners of the lips to twist sideways toward the ears.
It is also frequently asymmetrical, as the related article for nose crinkle ("similar to a sneer") shows:


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Important Jewelry
Antique Colored Pearl and Diamond Necklace, composed of seventy-five pearls graduating in size from approx. 4.09 to 10.15 x 9.91 mm, completed by an old mine-cut and diamond clasp, lg. 22 in.
Note: Accompanied by GIA report no. 2191757759, dated October 26, 2018, stating that the pearls are natural and undetermined, freshwater and saltwater.
Estimate $3,000-5,000
The absence of a condition statement does not imply that the lot is in perfect condition or completely free from wear and tear, imperfections or the effects of aging. Condition requests can be obtained via email (lot inquiry button) or by telephone to the appropriate gallery location (Boston/617.350.5400 or Marlborough/508.970.3000). Any condition statement given, as a courtesy to a client, is only an opinion and should not be treated as a statement of fact. Skinner Inc. shall have no responsibility for any error or omission.


text: Delegated Access overview: A useful component that comes with Windows Virtual Desktop is the WVD delegated access model. This function lets you define and control access at various levels of the WVD Structure. The role assignment has three key components, which include: Security principal, Role definition and Scope. One point to note is that WVD... Continue Reading →


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Archive for the 'Fragrance' Category
New Adventures This Fall
written by Raulla S. Mitchell"Life is like playing a violin in public and learning the instrument as one goes on." Samuel Butler (1835-1902) Victorian author and poet
Fall is a time for new adventures. What do you dream of learning? What's on your bucket list? → Read more
Citrus Coolers
written by Raulla S. MitchellWhen August temperatures soar, break out the juicy citrus scents and celebrate with a citrus fest.
We asked, and you told us. Your favorite summer fragrances – CITRUS!
Instantly revive and uplift your mind, body and spirit! Three of our most succulent, refreshing CITRUS fragrances to help beat the summer heat. Tried them yet?
written by Raulla S. Mitchell
Long hot midsummer days cooled by end of the driveway neighborhood lemonade stands and swimming pools. Wet children and dogs. Packing for summer camps and long holiday weekends. Sunburns, insect bites, picnic lunches at the beach, patio dinners on the grill, conversations into the night under the stars. Thoughts of work and school routines fade. Schedules seem more elastic. Release yourself to the easy flow of summer.
At the end of your day, whatever the temperature outside, a warm bath remains an inviting treatment for summer skin. Unwind in a realm of tranquility or energize your spirit for a night out, perfect for whatever the evening holds in store for you. Luxuriate in two of our yummiest bestseller summer fragrances… DREAMSICLE SMILES and MIMI A TAHITI! → Read more
Midsummer Pleasures
written by Raulla S. Mitchell
Indulge in summer's freedom to play with everything, including fresh natural skincare for the bath products and fragrances.EXPLORE NEW FRAGRANCES → Read more
written by Raulla S. Mitchell
The start of summer is the perfect time to play with our lusciously juicy citrus fragrance collections with essential oils of orange, lemon, lime, tangerine, lemongrass and grapefruit! Summer relaxes the go-go girl in all of us, and is there anything more soulfully refreshing than citrus energy? We don't think so! Citrus beauty just makes me want to jump in! How about you, cherie? Carpe diem, in a sensually indulgent way unique to gorgeous YOU! → Read more
written by Raulla S. Mitchell
Some of you prefer 100% pure aromatherapy essential oils to fragrance skincare for the bath products whenever possible. We understand, especially if you've experienced a sensitivity to some synthetic fragrances.
Our essential oils are ALWAYS 100% pure, authentic and genuine. They are NEVER diluted with carrier oils that can negatively effect the quality and shelf-life of your essential oils.
Sometimes to give you a more beautifully unique and complex fragrance blend that's not available with only fragrant essential oils, we blend our 100% pure essential oils with high quality synthetic (phthalate-free) fragrances to create the most elegant, refreshing, and playful fragrances we all adore.
Just one sec here: Before we jump into talking about an important issue inherent with the use of essential oils in skincare products, an issue which most people don't think about when touting the benefits of essential oils and citing the potential negatives associated with synthetic anything, including fragrances (e.g. sensitivities, allergies, irritation, etc.), let me tell you that very often, the primary culprit associated with synthetic fragrances is PHTHALATES. Phthalates are the chemical compounds which can, in some individuals, cause headaches, respiratory irritation, and other temporary sensitivities. Our highest quality synthetic fragrances are phthalate-free, for just that very good reason.
Want to know more about phthalates? Several of you have asked me about this, so I'll include a new post on the topic. If you can't wait to know more, shoot me an email, and I'll share with you the scoop on phthalates, and why you can expect to see more and more quality beauty products listed as phthalate-free.
But, for right now, here's a very important reason for using phthalate-free fragrances (rather than essential oils) when you're out in the summer sun: PHOTOSENSITIVITY.
It's important for you to know that just because we use 100% pure essential oils (not adulterated or blended with carrier oils which risk reducing their fragrant potency, therapeutic effectiveness and natural shelf-life), this does not mean that these essential oils are free of potential cosmetic issues when we expose our skin to the sun. → Read more
written by Raulla S. Mitchell
Your daughter's home from school! Woo hoo!
For how long? Is she going off to camp? For just the day? Or is it time for her weekly getaways? Always so hard. I get it, and you'll never stop missing her while she's away. One thing that helps, just a little bit? Mommy and me skincare.
Because fragrance is memory,… and fresh natural luxury skincare and luscious fragrances seem too wonderful a secret to keep to yourself.
I know you want to share the dreamy pleasures of beautiful gentle products with your family and friends, and this includes, above all, your daughter (younger sister, niece, granddaughter, god daughter, or any special lovely young girl in your life) who loves fragrances and skincare products made just for her, sweet juicy love in a bottle or jar to nurture her skin.
You'll love them too of course!
We've created two luscious Mei Mei et Maman (Mommy and Me) fragrance collections… → Read more
written by Raulla S. Mitchell
One word with enormous power to make the difference between healthy radiant skin that you dare to bare, and skin you'd rather keep under wraps this summer: EXFOLIATE. Yes, it's a really big deal. You only have to try it once to notice immediate benefits. When you make it part of your weekly skincare routine, you'll continue to notice your best skin ever – healthy, soft, smooth skin that returns the love you give it! → Read more
written by Raulla S. Mitchell
May is all about love: first love, new love, mom's love, love for mom, love for newborn baby animals and their angels with fur kinda love for us,…. Love of all kinds as a vital force inspires us to feel happy, young and exuberant, and want to share all this luscious energy with our family and friends and smile at people we may never know other than in passing for a moment in time. → Read more
L'Amour Fou de Printemps
written by Raulla S. Mitchell
May is the perfect time to play with new spring fragrances. Everything around us seems more playful, delightful and full of intoxicating natural fragrances and joie de vivre, so welcome l'amour fou (crazy wild love) of springtime into your heart! Fragrance is all about happy little sensual pleasures, feeling fab in your skin and making beautiful memories that remain forever. Franz Kafka said "Anyone who retains the ability to see beauty never grows old." I couldn't agree more. Fist bumps Franz and Andre (Breton), l'amour fou man. And the best part? Crazy wild love and this genuine fountain of youth are available to you, everyday of your life. Just choose to invite them into your life today. → Read more


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Mcpx Quotes
Completely automating your plant is a substantial investment. But over time, the efficiencies produced from automation pay off. The MCPX trade show allows our members to see and touch the latest products and technologies both European and domestic in order to make decisions about the future of their plants. - Ty Gable
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text: I would like to start by saying Debra is much more than a Realtor. She goes above and beyond what most Realtors do. She truly cares about her clients. She spent many hours with us house hunting when we finally found our home. She walked through and made sure anything she thought should be included was included or asked for it to be included. She went to our closing with us, so that if we had any questions she could answer them or the builder would before we signed. If we were ever looking to sell she would definitely be our Realtor. If you are looking not just for a Realtor but someone who knows realty Debra is definitely who you are looking for.


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Hey Galaxy-dev's,
I'm completely new to galaxy, but I am tasked with a small scale deployment project.
I am looking for an alternate option to upload data to galaxy. All data from our sequencers is stored on a NAS, which is accessible by the galaxy server. I would like to make it so that the users can only select data from that folder, to eliminate
the need to transfer data through the client to the server.
Is there any way to do this? Or am I making this to hard on myself?
Matthias De Smet
Centrum voor Medische Genetica
De Pintelaan 185 - 9000 Gent
[hidden email]
tel.: +32 (0)9 332 0296
Please keep all replies on the list by using "reply all"
in your mail client. To manage your subscriptions to this
and other Galaxy lists, please use the interface at:
To search Galaxy mailing lists use the unified search at:


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Buhais Geology Park opens in UAE's Sharjah Desert
January 31, 2020 by
Filed under Green
Comments Off on Buhais Geology Park opens in UAE's Sharjah Desert
British architectural firm Hopkins Architects has completed the Buhais Geology Park Interpretative Centre, a new research and education facility highlighting the "prehistoric and geological significance" of the former seabed known as al-Madam Plain. Located southeast of the UAE city of Sharjah, the Geology Park was created as part of a series of learning and conservation centers operated by Sharjah's Environmental Protected Areas Authority. The design of the site-sensitive complex comprises five interconnected pods inspired by prehistoric sea urchin fossils. The Buhais Geology Park Interpretative Center is located within the Jebel Buhais, an archaeological site that's most notable for its extensive necropolis spanning the Stone, Bronze, Iron, and Hellenistic ages, as well as for its abundance of marine fossils from over 65 million years ago. To highlight the archeological importance of Jebel Buhais, the Park was conceived as an important educational resource and destination for tourism. Taking cues from the region's well-preserved prehistoric fossils, the architects crafted the Interpretive Center into five interconnected pods that house a series of exhibition spaces with model-based interactive displays as well as an immersive theater, a cafe with panoramic views of the dramatic Jebel Buhais range, a gift shop, and other visitor facilities. An outdoor trail accessible from the main exhibition area links the pods and includes viewing areas of the mountains, a classroom shaded by a high-tensile canopy, and raised walkways across select geological sites of note such as ancient burial grounds. Related: Off-grid Fossil Discovery Exhibit camouflages into the Texan desert "Our first sight of Jebel Buhais was in the late afternoon sun, exploring the area after the midday heat," Simon Fraser, Principal at Hopkins Architects, said. "It is an amazingly beautiful, barren setting, with the Jebel providing a powerful backdrop. We have ensured that our design touches lightly on this fragile landscape, so rich in remarkable fossils and prehistoric burial sites. This exciting new facility will allow thousands of people from all over the world to understand the way in which landscapes are formed by tectonic activities and how the Earth has changed over time." + Hopkins Architects Images © Marc Goodwin
Original post:Â
Buhais Geology Park opens in UAE's Sharjah Desert
Off-grid Fossil Discovery Exhibit camouflages into the Texan desert
March 28, 2018 by
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Big Bend National Park isn't just a place of stunning landscape beauty—the Texan park is also paleontological paradise. To tell the story of the area's rich fossil history, Texan architecture studio Lake | Flato designed the Fossil Discovery Exhibit, a series of interpretive pavilions that draws inspiration from the surrounding topography. The unstaffed, low-maintenance building operates off grid and draws energy and water from solar panels and a rainwater catchment system. Created as a series of open-air pavilions , the Fossil Discovery Exhibit takes visitors on the Big Bend Fossil Discovery Trail: a sequential walkway that covers four paleontological eras from the Early Cretaceous period to the Cenozoic Era. "The complex story of Big Bend's remarkable landscape can be brought to life through its fossil history and the artifacts found within the park," wrote the architects. "These characteristics create a unique opportunity for interpretation and education; the trail will describe the world-class diversity and length of Big Bend's fossil history while directly referencing the breathtaking surrounding landscape." Related: Philip J. Currie Dinosaur Museum is sustainably built from CNC-milled beetle-kill timber Elevated on concrete piers, the building is clad in perforated weathering steel for low maintenance and camouflage so as to avoid disrupting views from the road and trails. Interior partitions guide visitors through the spaces, the highlight of which is the Gallery of the Giants where massive bones and recreated skeletons are on display. Solar panels power the buildings, while the angled roof, which evokes a winged dinosaur, is optimized for rainwater collection. + Lake | Flato Via Dezeen Images by Casey Dunn
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Off-grid Fossil Discovery Exhibit camouflages into the Texan desert
Kengo Kumas competition-winning aquatic center connects land and sea in Copenhagen
March 28, 2018 by
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Kengo Kuma & Associates beat out the likes of BIG and 3XN Architects in a design competition for a new waterfront cultural center that will form part of Copenhagen's artificial Paper Island (Papirøen). Chosen unanimously by the jury, Kuma's winning scheme will offer leisure and recreational facilities housed within pyramidal volumes echoing the roof profiles of Christiansholm island. The buildings will also be built of brick in reference to traditional Danish craft. Revealed earlier this year, Kuma's designs for the Papirøen Waterfront Culture Center were created in collaboration with Danish subcontractors Cornelius Voge, Soren Jensen engineers and Niels Sigsgaard. The 53,820-square-foot complex will be developed as part of COBE's competition-winning masterplan for Paper Island . The masterplan and the waterfront cultural center are slated for completion by 2021. "The new Waterfront Cultural Center with Harbor baths at Paper Island is to highlight the significance of water in the history, culture and vibrant urban life in Copenhagen ," wrote Yuki Ikeguchi, Partner in charge. "Our focus in design is to create an experience, and not just a standalone object, in the form of the landscape, art and architecture that are unified and defined by the water. Our design proposal strives to offer the diverse experiences of water in various states and conditions such as reflection of light and shadow, steam and flow that appeal to human senses." Related: COBE Architects to transform Copenhagen's Paper Island into a bustling cultural hub The cultural center is located on a corner site and will offer expansive views of the water inside and out. Skylights punctuate the cone-shaped buildings to let natural light into the ground-floor pools. The perforated brick facade also allows diffused light inside. + Kengo Kuma & Associates Via ArchDaily Images via Kengo Kuma & Associates
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Kengo Kumas competition-winning aquatic center connects land and sea in Copenhagen


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Pit Buehler: Insides
The latest shooting with him, an awesome and special experience. I had such a great time. Soon there will be more !
As one of my favourite artists, Pit Buehler (www.blackocean.ch) combines art, statement and the eye for the essence.
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Dorothy B. Dobson
September 17, 1926 ‒ January 12, 2008
Gambier, Ohio
Dorothy B. Dobson, 81, of Chase Ave., Gambier passed away on Saturday morning, January 12, 2008 at the Country Court Nursing Home in Mount Vernon. She was born on September 17, 1926 at Brinkhaven, a daughter of the late William and Goldie (Dobson) Wilson.
Dorothy was a homemaker and she enjoyed working in her flower garden and spoiling her grandchildren.
Dorothy is survived by her son and daughter-in-law, David and Teresa Dobson of Mount Vernon; her grandchildren, Challyn, Brie, and Michelle Dobson all of Mount Vernon; her brother, Robert D. Wilson of Mount Vernon; and several nieces and nephews.
In addition to her parents, Dorothy was preceded in death by brothers, Orvy, William, Gerald, and Roy Wilson; and sisters, Erma Crosky, Beatrice Wilson, Elsie Harding, and Mary Jane Magers.
The family will receive friends from Noon until the time of the funeral services at 1 p.m. on Wednesday, January 16, 2008 at the Dowds-Snyder Funeral Home, 201 Newark Road, Mount Vernon with Evangelist Jerold Tear officiating. Burial will follow in the Oak Grove Cemetery in Gambier.
In lieu of flowers, memorial contributions may be made to Hospice of Knox County, 17700 Coshocton Road, Mount Vernon 43050 or to the College Township Fire Department, P.O. Box 109, Gambier, Ohio 43022
Online condolences may be expressed to the family by visiting www.snyderfuneralhomes.com


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Now showing items 1-3 of 3
Business impact, risks and controls associated with the internet of things
(Stellenbosch : Stellenbosch University, 2017-03)
ENGLISH SUMMARY : Modern businesses need to keep up with the ever-evolving state of technology to determine how a change in technology will affect their operations. Adopting Internet of Things to operations will assist ...
The development of a framework to achieve alignment between information technology (IT) and business objectives while adhering to it governance principles
(Stellenbosch : Stellenbosch University, 2017-03)
ENGLISH SUMMARY : Information technology (IT) is developing at an accelerated rate, making it virtually impossible to separate business and IT strategy. The rate, scope and impact of recent technological advances has led ...
A structured approach to the implementation of information technology (IT) governance principles to address application software project failure at a strategic and operational level
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Application software projects continue to fail at an alarming rate, despite extensive research on the subject and various attempts by organisations to prevent such failures. These failures are mainly ...


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The Hunt for 30% Off Begins Now!
From now until Monday, 11/26, enjoy 30% off your entire purchase with code: "BF2018"! Hunt what feeds you!
About HNTR
HNTR aims to encourage men and women to tap into their innate power to be more aggressive in accomplishing their goals. Our brand draws influence from the constellation Orion, the hero and great hunter. Like a hunter, we emphasize finding your true aim, following that passion, and hunting what feeds you. Through our products, we hope to help empower those who wear them and inspire others on the same journey of finding their greatest self.


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Seeking an exemplary board-eligible/board-certified Gastroenterology physician. Covenant Medical Group and a well-respected private Gastroenterology practice invite you to work with an experienced, board-certified Gastroenterologist while you grow your medical practice. Enjoy excellent work-life balance in the lively city of Lubbock, the heart of west Texas.
Where You'll Work
Covenant Medical Group is the largest medical group in the West Texas and Eastern New Mexico region. Headquartered in Lubbock, Texas, Covenant Medical Group serves a population of 1.2 million people, employing more than 260 providers in approximately 30 specialties. Covenant Medical Group providers understand that a trusted health care partnership between patients and providers is crucial and involve patients in the decisions that impact their health and wellness.
Where You'll Live
Lubbock is considered the economic, educational and health care hub of the Texas South Plains. With a population of 250,000, Lubbock is a thriving metropolis in the heart of the largest contiguous cotton-growing region in the world. Home to several universities, including Texas Tech, Lubbock also boasts an excellent school system. This vibrant city offers a variety of entertainment options, including a summer concert series, a rich cultural district and a family adventure park.
Who You'll Work For
Covenant Health is a comprehensive health network serving West Texas and Eastern New Mexico. Part of the Providence family, Covenant employs more than 12,000, including 600 physicians at five hospitals, with more than 975 beds, and 20 clinics. Headquartered in Lubbock, Texas, Covenant includes multiple Centers of Excellence, including the Joe Arrington Cancer Center and the Covenant NeuroScience Institute. It is dedicated to its mission to serve all, especially those who are poor and vulnerable.
IS: No
YM: No
Let's get in touch
If you have questions about this specific job or others, I'm all ears. Send me a note and we'll be one step closer to the right opportunity.
Kelly Fortney
Provider Recruiter
Show Contact Details(806) 725-7875
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Contact InformationShow Contact Details
Covenant Health is a comprehensive health care network headquartered in Lubbock, Texas. A partner organization of the Providence St. Joseph Health family, Covenant operates five hospitals, six specialty centers, and more than a dozen clinics serving West Texas and Eastern New Mexico. Covenant seeks to care for the whole person by striving for sacred encounters and excellent care in every patient interaction. Covenant is proud to be an Equal Employment Opportunity organization.
Provider Solutions + Development creates healthier communities by forging lasting partnerships between providers and not-for-profit health systems. For 20+ years, we've helped thousands of physicians and advanced practice clinicians achieve their practice potential by consulting, mapping and managing their career moves.
Founded within Providence Health & Services, we're now a clinical career navigation group with a purpose-driven culture. Some of the nation's preeminent health systems entrust us with finding the right providers – not just any providers – for mutual, long-term success.
We're here to help you discover, select and manage the next step in your career journey. Where would you like to go?Back to top
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Fraunhofer FHR develops novel multi-band antennas for ships radar SEERAD
If a person goes overboard on the high seas and gets out of sight, it is almost impossi-ble to detect the person in the water using the... [mehr]
Fraunhofer-Institut für Hochfrequenzphysik und Radartechnik FHR
If a person goes overboard on the high seas and gets out of sight, it is almost impossi-ble to detect the person in the water using the... [mehr]
Millimeter waves are capable of penetrating non-conductive materials, so-called dielec-trics. Thus, they are particularly suitable for the use in... [mehr]
In cooperation with top-level partners, Fraunhofer FHR will present the latest research results and projects in the field of high frequency and... [mehr]
Radar sensors are important components for modern automobility. Not least due to the rapid developments being made in the field of autonomous... [mehr]
With SAMMI®, Fraunhofer FHR offers a complementary application for the quality control of food, piece goods, and bulk goods. The use of high... [mehr]
In addition to two talks on the topics of "Direction of arrival estimation techniques for passive radar based 3D target localization" and "Minimum... [mehr]
Their space radars TIRA and GESTRA present researchers with examples of their use at the ESA Neo and Debris Detection Conference from 22 to 24... [mehr]
Driver assistance systems have to ensure reliable operation in the whole range of different traffic conditions: In city traffic, for instance,... [mehr]
Especially the high costs of commercially available radio and position finding systems, amounting to more than 300 euros per person, have... [mehr]


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diff options
Diffstat (limited to 'mcon/U/d_gconvert.U')
1 files changed, 4 insertions, 4 deletions
diff --git a/mcon/U/d_gconvert.U b/mcon/U/d_gconvert.U
index dbc67f0..fccb13b 100644
--- a/mcon/U/d_gconvert.U
+++ b/mcon/U/d_gconvert.U
@@ -1,11 +1,11 @@
-?RCS: $Id: d_gconvert.U 1 2006-08-24 12:32:52Z rmanfredi $
+?RCS: $Id: d_gconvert.U 167 2013-05-08 17:58:00Z rmanfredi $
?RCS: Copyright (c) 1991-1997, 2004-2006, Raphael Manfredi
-?RCS: You may redistribute only under the terms of the Artistic Licence,
+?RCS: You may redistribute only under the terms of the Artistic License,
?RCS: as specified in the README file that comes with the distribution.
?RCS: You may reuse parts of this distribution only within the terms of
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Victor Webster Biography
Birthday: February 7, 1973
Nationality: Canadian
Famous: Actors Canadian Men
Age: 47 Years, 47 Year Old Males
Sun Sign: Aquarius
Born in: Calgary
Famous as: Actor
Height: 6'3" (190 cm), 6'3" Males
father: John Webster
mother: Roswitha
City: Calgary, Canada
education: Saddleback College, San Clemente High School
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Victor Webster is a Canadian actor, best known for his iconic role of 'Nicholas Alamain' in the soap opera 'Days of Our Lives.' Born and raised in Alberta, Canada, he had an aggressive streak, which made him pursue a career in martial arts. However, he had an affinity for acting since early childhood and that made him participate in school plays and attend theater classes. He arrived in the US in the late 90s, and while looking for work, he landed a 3-episode role in the American TV series 'Sunset Beach.' However, it was his role in the daily soap 'Days of Our Lives' which brought him mainstream success. He followed it up with the action series 'Mutant X' and also made his film debut with 'Bringing Down the House.' Some of his other key films are 'Charmed,' 'Criminal Minds,' 'Harper's Island,' and 'Girlfriends' Guide to Divorce.' Lately, he has been closely associated with the 'Hallmark Channel' and has appeared in many of their TV films, such as 'Love Blossoms,' 'A Harvest Wedding,' 'Summer Villa,' and 'Home for Christmas Day.'
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- Victor Webster was born in Calgary, Alberta, on February 7, 1973, to John Webster and Roswitha. Victor was a mischievous teenager and often got into serious trouble. Following repeated complaints from his school and neighborhood, his father got him enrolled at a martial arts school. This was done in order to channelize his energy elsewhere.Victor's father was a police officer and his mother worked as a hairstylist. A few years after he was born, the family moved to San Clemente, where Victor completed high school.Apart from training in martial arts, Victor was also interested in theater. Once he graduated from high school, he resumed his studies at the 'Saddleback Junior College.'He earned a heavyweight black belt in 'Tae kwon do' and to make ends meet, he started teaching martial arts. However, his career goal was not defined yet. He slowly lost interest in martial arts and decided to pursue acting as a career option.It was not easy for him to break into acting. He had to work as a stockbroker while he tried becoming an established actor. He also worked in a major import/export company.Victor travelled across the world in search of inspiration, as he was highly confused about his career. Eventually, he joined acting classes and also worked in a few commercials, before finally deciding that acting was his true calling.Soon, he started working as a model and made an appearance in the 1998 special issue of 'Cosmopolitan' magazine, titled 'All About Men.' He also appeared on the cover of 'Playgirl' magazine. He moved to Los Angeles and started auditioning for roles, and luckily enough, his initial struggle did not last very long.Continue Reading BelowYou May LikeRecommended Lists:
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- By 1997, Victor had already made his acting debut with a minor role in the series 'Sunset Beach.' He had a three-episode long appearance, which was not bad for a newcomer.It was the daytime opera 'Days of Our Lives' that finally brought him national recognition in 1999. He became the second actor to portray the iconic role of 'Nicholas Alaiman.' The show received immense critical acclaim. His stint in the show ended in 2000, and he moved on to play smaller roles in series such as 'Baywatch' and 'Becker.'In 2000, he played a minor role in the film 'Gangland.' While waiting for another major career breakthrough, he auditioned and got selected for the role of a mutant, 'Brennan Mulwray,' in the series 'Mutant X,' in 2001. The series was a science-fiction drama, which told the story of people equipped with supernatural powers. The series ran for three seasons, before being cancelled abruptly.By then, he had gained national recognition and the icing on the cake was his inclusion in 'People' magazine's '50 Most Eligible Bachelors' list, in 2002. The same year, he appeared in a direct-to-video film, titled 'Wishmaster: The Prophecy Fulfilled.'In 2003, he made a guest appearance in an episode of 'Sex and the City' and played the role of 'Glen' in the comedy 'Bringing Down the House.'2005 was a busy year for Victor. He appeared in the film 'Dirty Love' and then, was seen playing some key roles in series such as 'Las Vegas,' 'Inconceivable,' and 'Noah's Arc.'In 2006, the action-comedy series 'Related' offered him the chance to play a key character, 'Marco.' Although he had a guest appearance on the show, his portrayal received immense accolades. The same year, he played an eight-episode role in the series 'Charmed' and also appeared in the series 'Reba.'In 2007, he appeared in two crime dramas, 'CSI: Miami' and 'NCIS.' He also did a TV science-fiction film 'Sands of Oblivion' and played the role of 'Dr. Christian Mario' in the series 'Lincoln Heights.'Victor had a recurring role in the series 'Melrose Place' as 'Caleb Brewer' and followed it up with the villainous role of a con artist-turned-serial killer in 'Criminal Minds.' He also starred in the murder mystery 'Harper's Island.' Thus, it seemed that Victor was finally experimenting with different characters in order to locate his comfort zone.All through 2010 and 2011, he appeared in several guest roles, spanning across many TV series such as 'Bones,' 'Castle,' 'NCIS: Los Angeles,' and 'CSI: Crime Scene Investigation.' At the same time, he also appeared in the film 'Burning Palms.'In 2012, he was selected to play one of the lead roles in the series 'Continuum.' The science-fiction series revolved around the complexities of time travel and starred Victor as 'Carlos Fonnegra,' a detective. The series earned universal critical acclaim and was commercially successful too. It earned several nominations and awards at the 'Leo Awards' and the 'Constellation Awards.'By the year 2013, Victor had become a known face in the industry and was offered major roles in both theatrical and TV films. While 'Continuum' ran successfully until 2015, Victor became part of projects such as 'Puppy Love,' 'A Good Man,' and 'Embrace of the Vampire.'In 2015, he appeared in the direct-to-video period epic 'The Scorpion King 4: Quest for Power' and played a major role in the critically acclaimed film 'The Dying of the Light.' The same year, he played guest roles in the series' 'Mom' and 'Girlfriends' Guide to Divorce.'Of late, his collaborations with 'Hallmark Channel' have grown in number. His association with 'Hallmark' began with the 2015 film 'The Magic Stocking,' and flourished through 2016 and 2017, with 'Summer Villa,' 'A Harvest Wedding,' 'Love Blossoms,' and 'Home for Christmas Day.'Personal Life
- Victor Webster has had several relationships with his co-actors. In the late 90s, his relationship with Krista Allen was in the news for quite some time.He is also said to have been in relationships with Katie Cleary, Katrina Darrell, and Monica Hansen. At present, he is believed to be single.Translate Wiki to Spanish, French, Hindi, Portuguese
How To CiteArticle Title- Victor Webster BiographyAuthor- Editors, TheFamousPeople.comWebsite- TheFamousPeople.comURL- https://www.thefamouspeople.com/profiles/victor-webster-35256.phpLast Updated- January 24, 2018
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