text:
Virtual Library
Start Your Search
W. Yu
Author of
OA 17 - Immunotherapy II (ID 683)
- Event: WCLC 2017
- Type: Oral
- Track: Immunology and Immunotherapy
- Presentations: 1
- Moderators:Yuichiro Ohe, Anne Tsao
- Coordinates: 10/18/2017, 14:30 - 16:15, Room 301 + 302
OA 17.07 - Long-Term Survival in Atezolizumab-Treated Patients with 2L+ NSCLC from Ph III Randomized OAK Study (ID 8663)
14:30 - 16:15 | Author(s): W. Yu
- Abstract
- Presentation
- Slides
Atezolizumab (anti–PD-L1) inhibits PD-L1 binding to PD-1 and B7.1, restoring anti-cancer immunity. OAK, a Phase III study of atezolizumab vs docetaxel demonstrated superior OS of atezolizumab. The characteristics of the long-term survivors (LTS) in the OAK primary population (n = 850) are evaluated and describe the largest cohort of cancer immunotherapy-treated NSCLC LTS yet reported.
Patients received IV q3w atezolizumab (1200 mg) until PD / loss of clinical benefit or docetaxel (75 mg/m[2]) until PD / unacceptable toxicity. No crossover was allowed. LTS were defined as patients with OS ≥ 24 months and non-LTS as those who died within 24 months of randomization. Patients with OS censored prior to 24 months were not included. Data cutoff, January 23, 2017.
A higher 2-year survival rate was observed for the atezolizumab-arm (31%) vs docetaxel-arm (21%). After a minimum follow-up of 26 months, there were 119 LTS vs 279 non-LTS in the atezolizumab-arm and 77 LTS vs 299 non-LTS in the docetaxel-arm. Characteristics of atezolizumab-arm LTS and non-LTS are shown (Table). Atezolizumab-arm LTS were enriched for non-squamous histology and high PD-L1–expressing tumors, but also included low/no PD-L1–expressing tumors (40.3%). Atezolizumab-arm LTS had higher ORR (39.5%) than non-LTS (5.0%) but included LTS subjects with PD. 52.9% atezolizumab-arm vs 71.4% docetaxel-arm LTS received anti-cancer non-protocol therapy (NPT) after discontinuation of protocol-defined therapy. 51.9% of docetaxel-arm LTS vs 12.7% non-LTS received non-protocol immunotherapy. Median treatment exposure in atezolizumab-arm LTS was 18.0 months. Atezolizumab-arm LTS had a comparable safety profile to all atezolizumab-treated population.
Atezolizumab provides superior 2-year OS benefit vs docetaxel and is well tolerated. The majority of docetaxel-arm LTS received a checkpoint inhibitor as NPT. Atezolizumab LTS appeared to have favorable prognostic factors, including non-squamous histology, but notably were not limited to patients with RECIST v1.1 response or with PD-L1 expression.
Table. Characteristics of Atezolizumab-Arm Long-Term Survivors (LTS) vs Non-Long Term Survivors (Non-LTS) Atezolizumab LTS (n = 119) n (%) Atezolizumab Non-LTS (n = 279) n (%) Sex Male 61 (51.3) 183 (65.6) Female 58 (48.7) 96 (34.4) Tobacco use history Never smoker 29 (24.4) 47 (16.8) Current/previous smoker 90 (75.6) 232 (83.2) Histology Non-squamous 101 (84.9) 195 (69.9) Squamous 18 (15.1) 84 (30.1) No. of prior therapies, 1 89 (74.8) 209 (74.9) ECOG performance status at baseline 0 60 (50.4) 89 (31.9) 1 59 (49.6) 190 (68.1) EGFR mutation status, positive 11 (9.2) 26 (9.3) PD-L1 IHC subgroup TC3 or IC3 28 (23.5) 39 (14.0) TC1/2/3 or IC1/2/3 71 (59.7) 156 (55.9) TC0 and IC0 48 (40.3) 119 (42.7) Best overall response Complete response 5 (4.2) 0 (0) Partial response 42 (35.3) 14 (5.0) Stable disease 47 (39.5) 97 (34.8) Progressive disease 25 (21.0) 142 (50.9) IC, tumor-infiltrating immune cell; TC, tumor cell. TC3 or IC3 = PD-L1 ≥ 50% TC or 10% IC; TC1/2/3 or IC1/2/3 = PD-L1 ≥ 1% on TC or IC; TC0 and IC0 = PD-L1 < 1% on TC and IC. NCT02008227.
Only Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login, select "Add to Cart" and proceed to checkout. If you would like to become a member of IASLC, please click here.
Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.
P1.01 - Advanced NSCLC (ID 757)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Advanced NSCLC
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
P1.01-052 - Patient-Reported Outcomes (PROs) in OAK: A Phase III Study of Atezolizumab vs Docetaxel in Non-Small-Cell Lung Cancer (NSCLC) (ID 9903)
09:30 - 16:00 | Author(s): W. Yu
- Abstract
- Slides
The phase III OAK study in NSCLC (NCT02008227) demonstrated prolonged overall survival with atezolizumab (an anti-programmed death-ligand 1 antibody) versus docetaxel (median 13.8 vs 9.6 months; HR:0.73, 95% CI 0.62–0.87; p=0.0003). PROs were collected to support documentation of clinical benefit. We report data regarding symptom burden, functioning, and health-related quality of life (HRQoL).
Patients (n=850) with squamous/non-squamous, previously treated NSCLC, ≥18 years, with measurable disease (RECIST), and ECOG PS 0–1 were randomized to receive atezolizumab 1200mg or docetaxel 75mg/m[2] q3w. PROs were collected using two questionnaires: EORTC QLQ-C30 and its lung module, QLQ-LC13. Analyses included time-to-confirmed-deterioration (TTD) in lung cancer symptoms, physical and role function, HRQoL, longitudinal analyses of mean scores change from baseline to Cycles 5 and 6, proportion of patients with clinically meaningful worsening (≥10-point change from baseline) by Cycles 5 and 6.
High completion rates were observed throughout treatment (>80% for most cycles). Atezolizumab delayed TTD in physical (HR:0.75, 95% CI 0.58–0.98) and role function (HR:0.79, 95% CI 0.62–1.00). Prolonged TTD in chest pain (HR:0.71, 95% CI 0.49–1.05) was observed with atezolizumab; no differences in TTD were seen for other lung cancer symptoms and HRQoL. Longitudinal analyses demonstrated average changes from baseline in favor of atezolizumab for lung cancer symptoms (Cycle 6: dyspnea, fatigue), domains of functioning (Cycle 6: physical function, social function), HRQoL (Cycle 5); see Table. Fewer atezolizumab-treated patients experienced clinically meaningful worsening in possible treatment-related symptoms during treatment (Cycle 6: diarrhea [OR:0.51, p<0.0001], sore mouth [OR:0.40, p<0.0001], dysphagia [OR:0.61; p=0.0052], peripheral neuropathy [OR:0.50, p<0.0001], alopecia [OR:0.02; p<0.0001]).
In OAK, atezolizumab delayed the time until NSCLC patients experience limitations in physical and role functioning versus docetaxel. Patient-reported data indicate atezolizumab maintained/improved lung cancer symptom burden and HRQoL compared with baseline, while demonstrating improved tolerability, versus docetaxel.
By Cycle 5 By Cycle 6 LS means difference between treatment arms (average change from baseline) P value LS means difference between treatment arms (average change from baseline) P value EORTC QLQ-C30 Global Health Status and Function Scales (positive values indicate greater improvement with atezolizumab over docetaxel) Global Health Status 4.32* p=0.0151 3.08 p=0.1257 Physical Function 3.33* p=0.0290 6.64* p<0.0001 Role Function 2.93 p=0.1959 4.72 p=0.0542 Emotional Function 2.66 p=0.1110 1.92 p=0.2868 Cognitive Function -0.67 p=0.6790 -1.08 p=0.5309 Social Function 3.25 p=0.1159 4.68* p=0.0319 EORTC QLQ-C30 Symptom Scales (negative values indicate greater improvement with atezolizumab over docetaxel) Fatigue -6.27* p=0.0015 -7.66* p=0.0003 Nausea/Vomiting -0.37 p=0.7824 -0.18 p=0.9040 Pain 1.44 p=0.5132 -1.67 p=0.4727 Dyspnea -4.70* p=0.0317 -5.92* p=0.0138 Insomnia 3.50 p=0.1675 0.83 p=0.7564 Appetite Loss -2.94 p=0.1994 -4.49 p=0.0586 Constipation -0.31 p=0.8772 -0.33 p=0.8816 Diarrhea -3.14* p=0.0482 -2.05 p=0.1748 EORTC QLQ-LC13 Symptom Scales (negative values indicate greater improvement with atezolizumab over docetaxel) Dyspnea -1.66 p=0.3146 -4.80* p=0.0140 Coughing -2.60 p=0.2572 -1.38 p=0.5772 Sore Mouth -7.29* p<0.0001 -9.23* p<0.0001 Dysphagia -0.08 p=0.9595 -2.01 p=0.1575 Peripheral Neuropathy -12.98* p<0.0001 -15.71* p<0.0001 Hemoptysis -0.24 p=0.7365 -0.91 p=0.2080 Alopecia -50.59* p<0.0001 -47.04* p<0.0001 Chest Pain -0.91 p=0.6064 -0.58 p=0.7779 Arm/Shoulder Pain -2.27 p=0.3177 -0.58 p=0.8109 Pain in Other Parts 0.94 p=0.7197 -1.05 p=0.7034 *Values that are significantly in favor of atezolizumab versus docetaxel
Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.


text:
It wont cost you any endeavour to see why the owner of this boat is so elysian to see Cherlyn aboard. Her big boobies well-nigh sound out from under her dre Tags: amateur, backroom, big natural tits, big tits, blowjob, present is why Angelina steady volunteered to be a physical object of the boat crew. Summer is the temper of jeans shorts, sunkissed skin and corneous girls!
So please either register or login. Home Sex Dating Pleasure. Bdsm sado slave Sexy women with nice tita African tribe girl nude Bikini model riot Skinny girl puffy nipples.
Parked at Loopia Free asian cutie sex movies free sex videod Barely legal black teen - college dorm girls lesbian sex cindy craford porn videos. Hot amatuer teen free porn videos without cc free gallery redhead mature: Hot threesome sex shemale video gallery big tits interview amateur porn videos: Movie star sex videos sexy teen braces jizzed on operating table fuck porn, erotic beheading videos Asian sex movie gallery. Redhead Videos!
Thank you for visiting XXX Sexy Teens, if you need teen sex pics this place will surely will not likely leave you disappointed. We have whatever it takes to please every fan with slutty teenage girls. We are determined to bring to all our dear prospects only the finest XXX stuff.
These naughty Latina girls are more than happy to shed their clothes and expose their firm tits and shaved pussy for the camera. All galleries and links are provided by 3rd parties. Teen Porn Gallery In the mood for something you can jerk off to?
Welcome to our boat category! Of course, others might look more professional because they were done by pro photographers and everything will be incredible: light, position, scenery, models… Whatever your preferences are you will surely find something interesting in this category! All these photos are free for viewing and you can enjoy in them without worrying about payment and membership.

subset: commoncrawl


text:
Latin Dating in Brownsville
Your hotsy-totsy significant other for a delicious Latin Marriage in your location is in your hands! No more fly-away people or manipulators. The biggest number of users of different gender identities, generations, and orientations is within an easy reach. Feel free to choose from millions of users who are ready for a family role. Love will find a way and you should spend some time on our motivating hint on special features of Latin relations. Get the most of our most consummate matching without limitations. Your family is likely to start some mutual attraction and some dialogue. With the help of our web app you are sure not to be alone anymore! Discover pure.dating immediately for free because PURE.dating. is by far more valuable in comparison to all dating agencies. Our Latin user is sure to achieve special potential soulmates.


text:
Our Story
Necessity is the mother of invention.
Cassette was born to address one of the worst housing crises the U.S. has ever faced.
In 2019, Cassette founders embarked upon an investigative journey to uncover the obstacles preventing true construction innovation from widespread adoption. Detailed findings led to Cassette's integrated service model, and to its innovative delivery approach.
The business model encapsulates the belief that building is an intrinsically human exercise, and that groundbreaking innovation in this sector must be accompanied by a human-centric plan that ensures all at the table can succeed.
Cassette also believes that collaboration between the private and public sector can lead to added value for both, and a win for our communities. The company provides shelter for a transitional homeless person for every 100 housing modules sold in any given city, and asks those cities to participate in modular construction literacy workshops to advance the speed of housing production on every level.
Dafna Kaplan
Founder & CEO
Dafna Kaplan is the founding CEO of Cassette. As a veteran of both consumer tech and construction industries, she observed the need for a tech-driven innovator committed to working through and with the people that make buildings happen. Hence, Cassette's unique business model aims to lift all boats with the rising tide of industrialization.
Kaplan's career began with ten years of leadership in global branding and media communications in the software and consumer tech space, with her last role in that sector as Targus' global brand director. In 2004, Kaplan transitioned her marketing expertise to the architecture and construction sector, where she last served as a Vice President of Marketing at MATT Construction, a regionally acclaimed commercial construction firm in California.
Kaplan is passionate about giving back, and has served on association and non-profit boards for over two decades, including the Consumer Electronics Association accessories division board, the Executive and Management Committees of the Urban Land Institute in Los Angeles, the Architecture + Design Museum, and as Public Director on the AIA Los Angeles Chapter Board. She resides in Los Angeles, but travels extensively to research global technology and building trends.
Kaplan holds an MBA, Summa Cum Laude, from the UCLA Anderson School and a BA in Human Services from the University of Oregon.
Nick Butcher
Chief Operating Officer
Nick Butcher is both the Chief Operating Officer of Cassette, and its Board Director. His global construction experience and perspective inform the company's supply chain partnerships, quality assurance, and project management procedures.
He is known globally as a leader of cost management teams handling large scale and architecturally complex construction projects. He has developed an instinct for discerning and interpreting the main cost and risk drivers of a project early in conceptual design and providing pragmatic guidance with architectural sensitivity throughout design and construction.


text:
I have paid attention to what was going on in the United States economy from that time on. What I saw was a false economy and a sense of complacency as thinking I'm ok and your ok and tomorrow will even be better than today. I kept watching as companies would merger then layoff thousands this would happen over and over again. These were high paying jobs and the jobs that replaced them were nonessential low pay jobs. Inflation was creeping up unnoticed since 1972 with the first oil embargo. In 1968 I bought a new buick convertible and I was making $8 an hour as a union Plumber for $4200. and a new house for $11,000. Try and buy these same items for that amount in a upgrade neighborhood and see what you will have to pay. Has the majority of the peoples pay checks kept up with these items, certainly not. These items have more that quadrupled.
Another area to consider is the destruction from the storms that have been devastating this country for the last decade. Many people have lost every thing with out hope of recovering there loses, tornadoes, hurricanes, floods, droughts, heat waves, frosts ect. These acts of nature as the world calls them are not only costing in the turms of monitory loses, but they are depleting the food supply as well. Each time there is a disaster the government has to help which is a drain on resources but on the tax payer that is now already under the guns. The cost of medical care because of the increase of diseases, and Crime and the cost of trials and incarcerating these individuals. You can go on and on how our resources are being wasted, but for believer's we have a inexhaustible supplier Jesus Christ. You as a father being evil can give good gifts unto your children, how much more will your Heavenly Father give freely to you His children.
I would like to finish this letter on a positive note. When the Lord spoke to me about my economy going up he was speaking this word to all of us that have forsaken all in order to follow in the the foot steps of Jesus, after all He gave His all for us when we were still running from Him. It's not difficult to obey someone you know that loves you with a unconditional and sacrificial love that know one can understand until they have truly met Him. This is not for those who lust after the things of this world like the unsaved do looking for security in there own strength. Our benefits are out of this world waiting for us to believe and receive from the "All Sufficient One" Matt.6 seek first the Kingdom of God, and your benefits will be added unto you Psalm 103:1-3. It says in the scripture ! Cor. 2:9-10. V9 "Eye hath not seen nor ear heard neither entered into the heart of man, the things which God hath prepared for them that love Him. V10 But God hath revealed them unto us by His Spirit; for the Holy Spirit searches all things, yea the deep things of God." And in this day of uncertainty we can rest in the arms of Jesus. Prov. 1 :33 "But whoso hearkeneth unto me shall dwell safely, and shall be quiet from fear of evil."
Romans 15 : 13
May the God of hope fill you with all joy and peace as you trust in Him, so that you may over flow with hope by the power of the Holy Spirit.
Your Brother in Christ, Ed Hintz
" Attention Addendum"-
I have recalled to memory a dream the Lord gave me concerning the finances of the present and future ministries. In the dream I was walking towards a row of new homes under construction. I was a Plumber in construction of new buildings in Phila. Penna. and I worked on some new homes that were row type. This is what I saw, a row of homes that were incomplete showing only the basement which has the garage opening to an alley way, and the first floor, but the second and finale floor was not yet built. The interpetation of this is, I was heading towards my ministry I had not arrived at it yet. I knew that my ministy was in the basement (a ministry possibly obscure or under ground) I was impressed that the finances of this ministy would be lean and that it would be as Jesus said in Matthew 10 : 5-10. As I walked towards the houses I said "the workman here before me made a lot of money but it has changed, they will experiance leanness in fact they were not even working there any more. End of interpetation. I know this is not going to sit well with many infact I supposse it won't even be beleived, but God forbid that I don't sound the trumpit when I see trouble coming. I remain faithfull to you in Him. Edward J. Hintz
Here is a word that rings true, and those that can receive and do it it will be wise.
From the Holy Spirit
Given to Gaylene Womack
June 29, 2000
Third Day Visitation
Tuesday, June 27th (third day of the week) - The Lord led me to meditate on Exodus 19:10-25.
Wednesday morning I had received a prophecy, via email, with no headers or ident-ification numbers on it. Nothing!! It was sent only to me, no other names. It was from someone I don't have a clue to who they are and they used a pen name. It confirmed, in part, what I had been meditating in Exodus. Seemed like the Lord Himself sent the Word.
The Prophecy
Thursday, 3:48 a.m. the Holy Spirit woke me up and told me the following. He[the Holy Spirit] also told me to get up and look at the clock. Then He directed me to look up the meaning of 3:48. 3 = divine providence; 4 = earth, creator; 8 = new
beginnings, new creation; the total of the three numbers is 15 = rest,peace. This is only the second time the Lord has given me numbers for the purpose of understanding. Please prayerfully read the following:
Satan has seeded a false word amongst the church for the purpose of man not being prepared for what is really coming forth at this hour, this third day.
The false prophecy is "prosperity and power" and
coming as the latter reign. This word is true in part, it is not for the
overall church. For a prosperity of My Truth, not financial prosperity,
and anointing is coming forth but it is only for those that have sanctified
themselves and washed their clothes, that they may partake of My visitation.
Few there are that have done such a thing. There will be few that
will partake of this prosperity, that which comes from My Spirit.
Not material things, as such things many seek. Seek rather righteousness
and now I say, seek this diligently that this day does not pass with unrighteousness
found within your hearts. For as I told Moses to tell the people to sanctify
themselves and wash their clothes for the Lord shall come on the "third"
day. The "third" day is nigh upon thee and the "church" has not sanctified
themselves and washed their
clothes and will not partake of the "third day" visitation.
This visitation is only for those that have been separated unto Me and have dwelt in the wilderness and have been taught by My Spirit and not that of man. These are the virgins within the element of the church that I shall pour out My Spirit of the latter reign (Elisha double portion anointing) upon and they shall be hid (protected) in this the day that is upon you, My third day.
Many are called and few are chosen but because
of the false word sown within the church, you continued on your path of
degradation and immorality and have gathered up such treasures of defilement.
Look within your dwelling places and see what fills it. For where
your treasure is there is your heart. You have not separated from the world
and you still sit in the counsel of the ungodly. You listen not to
the quickening of My Spirit to bring you to repentance. For you must repent
in sackcloth and ashes (prayer and fasting), closing yourself in with Me
that I may search the very intents of your heart. I called many of
you but you did not heed my calling. You were too busy going here
and going there. Doing this and doing that. Party and play has been
the schedule of the day. You have not washed your clothes, separating
yourselves unto Me unto repentance and come forth out of the defilement
of the world and the possessions that dwell within your homes. Idols
stand within your walls.
This very thing alone testifies against you. You have not lived on bread alone as some have in the wilderness alone with Me.
A few willing hearts have come into the wilderness through the beckoning of My Spirit and there they have dwelt for years, being sanctified, washed and purified in My ways and My truth for two days. Now the third day is nigh upon thee and you are not prepared, forsaking all and coming to sit at My table. For they that have been in the wilderness truly have partaken at My
table. These are the ones that My Spirit will be poured out upon as the latter day reign, bringing unto Me the greater harvest as a reward for their righteousness that they have sought in Me and they have truly found. Vessels of honor they are unto Me. Their lives bare witness of the suffering of My Son.
Repent I say and seek righteousness that you may
be hid (protected) in My coming judgment and that you may be arrayed with
My clothes for the battle that will rage, between light and dark, righteousness
and unrighteousness, and is nigh at the door.
I am now ready to send forth My disciples. They have gone forth once without provision and now I will send them forth with provision. For their hearts are not on silver and gold, but on the true provision that comes from My throne.


text:
Family Llama Experience for Two Adults and Two Children
A brilliant Football Experience available in Towcester, Northamptonshire.
Llamas are perfect companions for an English country walk – affectionate, intelligent and happy to carry all your stuff! Begin with an informative introduction to llamas in the park and breeding centre's log cabin before embarking on your trek. Head out on a two hour adventure across country through a mixture of arable, pasture and woodland, taking in some pretty incredible sights along the way (one llama is shared between a child and an adult). After the trek, pay a visit to the farm to visit some llama mothers and babies and feel free to explore the park's visitor centre and gift shop which includes a host of wonderful 'llamarabilia'! Also, feel free to enjoy a picnic on the farm sample one of the local inns.
Llama treks are available all year round, any day of the week (with the exception of Christmas, Boxing and New Year's Days). We recommend booking with at least several weeks advance notice for the most popular peak summer weekend dates.
Trekking may be cancelled or curtailed in extreme weather conditions. Please call the centre before you leave if the weather looks bad or if there has been recent bad weather.
Your trek will last for around two hours. Please arrive 10 – 15 minutes in advance of the booked time to ensure a prompt start. The trek cannot be held up and any latecomers will forfeit their place.
Your trek consists of a small group of up to six people, your llamas and your guide.
Only paying guests may attend. Dogs are not permitted.
Dress for a walk in the country, in long trousers, sturdy waterproof clothes and footwear, plus a hat on a cold day. Some spare wellies, rain capes and gaiters are kept at the farm for use by customers just in case.
Two adults (over 18) to accompany up to two children who MUST be aged 8 – 12 years old. All participants must be reasonably fit and able to walk several miles (around three and a half to four). There's disabled access to the visitor centre.
Please note you won't ride the llamas. They are trusting creatures and must be treated with respect at all times. Lunch is not included.


text:
Objective Circulating endothelial cells (CECs), von Willebrand Factor (VWF) antigen, P-selectin and thrombomodulin are released from damaged endothelium, while decreases in circulating endothelial progenitor cells (CEPCs) have been associated with poor vascular outcomes. We examined these markers in the peripheral blood of juvenile dermatomyositis (JDM) patients and their correlations with disease assessments.
Methods Peripheral blood endothelial cells and biomarkers were assessed in 20 JDM patients, and matched healthy controls. CECs and CEPCs were quantitated by flow cytometry, while VWF antigen and activity, Factor VIII, P-selectin and thrombomodulin were measured in plate-based assays. Disease activity and damage, nailfold capillary (NFC) density, and brachial artery flow dilation were assessed. Serum cytokines/chemokines were measured by Luminex.
Results CECs, VWF antigen, Factor VIII, thrombomodulin, but not VWF activity, CEPCs or P-selectin, were elevated in the peripheral blood of JDM patients. CECs correlated with pulmonary activity (rs= 0.56). VWF antigen correlated with Patient/Parent Global, cutaneous and Extra-muscular Activity (rs= 0.47-0.59). CEPCs negatively correlated with muscle activity and physical function (rs= -0.52- -0.53). CEPCs correlated inversely with endocrine damage. VWF antigen and activity correlated with IL-10 and IP-10 (rs= 0.64-0.82),.
Conclusion Markers of endothelial injury are increased in JDM patients and correlate with extramuscular activity. CEPCs correlate inversely with muscle activity, suggesting a functional disturbance in repair mechanisms.


text:
|Date Posted:
|Mar 24, 2020
|Closing Date:
|Apr 12, 2020
|Work Type:
|Full Time
|Number of Vacancies:
|Functional Area:
|Education/ Training
|Salary Range:
|Salary is negotiableAF
|Years of Experience:
|5 - 6 Years
|Contract Duration:
|Open Ended
|Extension Possibility:
|Contract Type:
|Probation Period:
|6 months
|Required Languages:
About BRAC Afghanistan:
BRAC is a development success story, born in Bangladesh and expanding into 10 other developing countries in Asia and Africa. It spreads anti-poverty solutions making it a global leader in providing opportunities for the world's poor.
BRAC was founded in Bangladesh in 1972 by Sir Fazle Hasan Abed, and is today one of the top leaders in developing cost-effective, evidence-based poverty innovations in extremely poor, fragile and post-disaster settings. BRAC started its first programme outside of Bangladesh in Afghanistan in 2002 through its Dutch registered Stichting BRAC International. BRAC International is currently reaching over 19 million people beyond Bangladesh and creating opportunities to break the cycle of poverty.
With a holistic approach that uses a wide array of interventions including microfinance, education, healthcare, legal services and more, BRAC invests in communities' own human and material resources, catalyzing lasting change and creating an ecosystem in which the poor have the chance to seize control of their own lives. Of the world's top development and humanitarian relief organisations, BRAC is one of the few based in the global south. In February 2019, BRAC was ranked as the number one NGO in the world for the fourth consecutive year by the Geneva-based NGO Advisor, an independent media organisation committed to highlighting innovation, impact and governance in the non-profit sector.
BRAC International is seeking application from competent, dynamic and self-motivated individuals to fill the following position:
Job Summary:
This is a key position who oversees the project. This position is reportable to the Programme Manager.
Skills Required:
Provinces to travel:
Skills Description:
• Project Management.
• Expertise on community based education formal education, vocational education as well as education in emergency.
• Appropriate managerial skills and knowledge.
• English proficiency with advanced communication and reporting skills.
• Team building and leadership skills.
• Conflict resolution skills
Duties & Responsibilities:
• To lead and manage a project of 38 million USD to ensure secondary, higher secondary, technical and vocational education for around 50,000 girls in Afghanistan.
• Plan, execute, and facilitate the project interventions strictly according to the approved, plan, budget and timeframe.
• Manage resources and coordinate efforts of the team members to deliver the GEC-T project effectively and efficiently.
• Ensure that the project meets the stipulated and expected results of the project by overseeing the quality control of the whole project cycle.
• Manage day to day project operation following approved and agreed policy and procedure accordingly.
• Ensure team works for achieving the project target effectively by promoting team sprit as well as by controlling and leading the project staff.
• Ensure compliance to all relevant safety, health and environmental procedures across the department for building peaceful working environment.
• Ensure that different kinds of reports are submitted to donors on time and according to their requirement.
• Establish a safeguarding culture across all level of the program by implementing the safeguarding policy. Act as a key source of support, guidance and expertise on safeguarding for establishing a safe working environment.
• Responsible to ensure team members are appropriately trained, supported and have access to resources regarding issues that are identified and actioned in accordance with the safeguarding policy and procedure.
• Follow the safeguarding reporting procedure in case any reportable incident takes place, encourage others to do so.
• Other responsibilities as assigned by the management.
Job Location:Afghanistan, Kabul
• Masters in relevant subject
• Professional degree in Education is preferable.
Job Keywords:
Submission Guideline:
If you feel you are the right match for the above mentioned position, please follow the application instructions accordingly:
candidates need to email their CV with a letter of interest mentioning educational grades, years of experience, current and expected salary at firstname.lastname@example.com
Please mention the name of the position and AD# 10/20 BI in the subject bar.
Only complete applications will be accepted and short listed candidates will be contacted.
Application deadline: 12 April 2020
BRAC is committed to safeguarding children, young people and adults, and expects all employees and volunteers to share the same commitment. We believe every stakeholder and every member of the communities we work with has the right to be protected from all forms of harm, abuse, neglect, harassment, and exploitation - regardless of age, race, religion, and gender, status as an individual with a disability or ethnic origin. Therefore, our recruitment policy and procedure include extensive background checks and disclosure of criminal records in order to ensure safeguarding to the fullest extent.
BRAC is an equal opportunities employer


text:
Accounts Manager
- Apply
- Save job
Bullet points
Accounts Manager to join a successful, growing firm of Taunton accoutants.
Key managerial level hire, with increasing responsibility and progression.
About Our Client
A successful firm in Taunton, with a focus acting for growth focused clients with a good range of OMBs and SMEs, focusing entirely on the accounts, tax and wider associated general practice services provision to these clients, from a compliance angle and alongside this, offer wide ranging advice and planning services to their clients in addition as trusted business advisers to their clients . The firm is very forward moving and of a traditional accountancy practice mould, but rather embracing all the developments within the profession and maximising the potential from this. This approach is reflected across the wider business, with excellent benefits on offer in addition to an attractive and highly competitive salary package, with parking, additional annual bonus and other perks which can be explore on application and confidential discussion.
Job Description
Joining as Accounts Manager you will be responsible for a very varied client portfolio, across a wide range of industry sectors, including sole traders, partnerships and limited companies varying in turnovers, size and complexity. This role will be reporting directly to the directors of the accountancy practice and you will have the opportunity to take a lead role in developing this business and progress in your career. You will be dealing with the completion / reviewing of annual accounts and tax computations ensuring that all accounts & tax returns are filed with the relevant authorities on time, and clients accounting records are maintained accurately throughout the year. You will provide management figures, with regular client meetings and build long term, go to, trusted relationships with your clients. You will advise on the latest cloud software, review quarterly VAT returns & filing at HMRC in line with making tax digital, assisting in the review of monthly payrolls & filing at HMRC, proactively deal with client queries in a very varied role, carving a key managerial position within this growing firm of accountants.
The Successful Applicant
You will be ACA/ACCA qualified, or equivalent with a career background and strength within accounts/tax/audit etc and all around, general accountancy practice service delivery to wide ranging sole trade, partnership and limited company clients, developed within an accountancy practice firm environment. You will have developed your career to at least experienced 'Senior Accountant' or preferably Manager levels and be looking to take your career to the next level, within a firm and role where you can see a genuine clear progression and development path on offer.
What's on Offer
Circa £30000 - £40,000 dependent on the background experience and level of the right professional, plus benefits, negotiable. Please apply online and for a further confidential discussion please contact Mark Bailey on 01179271452 to find out more.


text:
Live Three Card Poker
Live casino games have never been bigger than they are right now, and live three card poker is just one brilliant game you can get into from the comfort of your home or with ease from your mobile phone or tablet.
But where can you find the best live 3 card poker games online in March 2020? Which sites are the ones to be trusted? Can you play on mobile?
All of these questions are about to be answered. Read on to learn more about live 3 card brag and to find out which sites are being ranked and rated as the best.
Best Live 3 Card Poker Sites
After researching 3 card online, we have found the best live three card poker sites.
bet365 Live CasinoNEW PLAYER BONUS UP TO £100
New Casino customers only. Deposit min. £10. Applies to first deposit to Casino only. Max. bonus £100. 15x wagering (game weighting applies) on deposit and bonus to make the bonus balance withdrawable. Time limits and T&Cs apply.
Slots MagicUP £50 WELCOME BONUS
First Deposit Only. Min. deposit: £10, max. Bonus £50. Game: Rich Wilde and the Book of Dead, Spin Value: £0.10, Max Extra Spins:50. WR of 30x Deposit + Bonus amount and 60x Extra Spin winnings amount (only Slots count) within 30 days. Max bet is 10% (min £0.10) of the extra spin winnings and bonus amount or £5 (lowest amount applies). Extra Spins must be used before deposited funds. Bonus Policy Applies.
William Hill Live CasinoUP TO £100 WELCOME BONUS
Opt-in required, 1x bonus per customer. 100% deposit bonus up to £250. Min deposit £10, max bonus £250 with 40x wagering. Bonus expires 72 hours from issue. Chip coverage restrictions, game weighting, games, player, currency, country restrictions & terms apply. New Player Offer. 18+.
Power Spins100% BONUS UP TO £100
New customers only. 100% up to £100 on 1st deposit. 65x wagering. Max bet 10% up to £2.50. Max win £2k. Selected games only. 7-day expiry. No Neteller/Skrill. Deposit/Withdrawal fees apply. Full T&Cs apply.
Casumo Casino100% WELCOME BONUS UP TO £300
Significant terms: 18+. No deposit for wager free spins. Opt-in required. Min £10 first deposit for a deposit bonus. 30x wagering requirement applies for deposit bonuses and winnings. Max £5 per spin or £0.50 per bet line. Contribution to wagering requirements varies per game.
Mr Green Casino100% DEPOSIT BONUS UP TO £100
T&Cs apply. New players only. Min. deposit £20. 35x wagering req. 18+. gambleaware.org
All British Casino100% WELCOME BONUS UP TO £100
New Customer Offer. T&Cs Apply. 18+. Please Gamble Responsibly.
Cashino Casino40 FREE SPINS WELCOME BONUS
New Customer Offer. T&Cs Apply. 18+. Please Gamble Responsibly.
PlayOJO CasinoGET 50 FREE SPINS
For Every £1 you deposit, 1 Free Spin will be credited. Up to 50 Free Spins on Spina Colada. Min deposit is £10. This offer is only available for first time depositors. Game: Spina Colada | Spin Value: £0.10. Also after your First Deposit you may claim an additional 20 Free Spins and a Free Spin on the OJO Wheel by visiting the Kicker Section. OJO's Rewards and Game Play policy applies. Read more.
Dunder CasinoUP TO £100 BONUS
Minimum deposit: £20. 20 spins in Book of Dead on reg. 100% bonus up to £100 and 100 bonus spins. First 50 bonus spins credited on deposit, Second 50 bonus spins credited the following day. Valid on first deposit only. Wagering on reload bonus: 60x. Wagering on bonus spins: 30x. Wagering must be completed within 30 days. Max bonus bet £5. Bonus is valid for a total of 21 days. Game weighting and standard bonus terms apply.
Cashpot Casino300% BONUS UP TO £1000
New Customer Offer. T&Cs Apply. 18+. Please Gamble Responsibly.
Betsafe CasinoUP TO 200 WAGER-FREE CASH SPINS
18+. 1st deposit only. Only 1 of 3 offers can be claimed. Available 14 days from registration. 3 day spins expiry applies. Any winnings credited as cash. Further eligibility and terms apply. Please Gamble Responsibly.
Live 3 Card Brag
Live 3 card brag is absolutely electric. The game was developed as an opportunity for poker fans to try a quicker, simpler variation on the wider game in a casino format.
While many casinos already offer poker tables where larger games can unfold, the table game format wasn't previously modelled towards the idea of making up the best 3 card hands and deciding whether or not you wanted to try your luck.
As such, the game of poker is effectively simplified and made even higher-octane by reducing the playing field to just two – that's you and a dealer – and the cards selection to just three.
Anyone who has played poker before will know the ins and outs of the game as a whole, but this game helps to make things that little bit more intense, and more appealing to online players. This type of 3 card just takes things to a whole new level.
Live Three Card Brag
Why play live three card brag? Here's some great reasons to get you started.
- Real time games feel authentic. While all of the sites and casinos we list here are verified as being fair, there's something that little bit more authoritative about a live-experience. If you feel as though you are really there, perhaps your chances feel a little stronger.
- These games are more intense. With just a table and some cards between you and a dealer, you no longer feel as though you're playing against a faceless machine. Live 3 card allows you to genuinely match wits with a dealer who is trying to outplay you. Use all the strategy and cunning you have in your arsenal.
- Every game is different. Different dealers will have different play styles and strategies, meaning that the game may even be a little trickier for you each time around. It's worth brushing up on the game and its general 3-card rules before getting started, of course, though you'll never know quite how some games are going to unfold.
Three Card Poker Live
Never played 3 card poker live before? Don't worry. While the game is generally supported widely by many big online casinos, it is still gradually making its way to the live-scene.
We've collected the best 3 card sites online currently offering live gaming to players, meaning that you can take our word for not only finding the game at any of these sites, but that you can also get into a fantastic player experience with plenty of chances for you to come away a winner.
We only ever work with the most functional and most generous of online casinos and gaming sites to bring you the best possible gaming experiences.
3 Card Brag Live Casino
3 card brag live casino games will, of course, come with that added element of risk. Seasoned braggers and bluffers who feel they know their way around a card emulation or two will likely find live games a genuine draw.
After all, as we've mentioned, no two games are ever going to be quite the same. And that's only part of the appeal. These games offer that fantastic casino atmosphere which – while supported hugely by computer-driven software and gaming – just elevates itself above the competition.
Ultimately, why go to the casino when the casino can come to you?
Live Dealer Three Card Poker
Live dealer 3 card poker isn't just available at home. You can now enjoy playing three card brag online with a real dealer on the go. Technology is advancing across major online casinos to bring these types of games and experiences to mobile players all over the world.
Therefore, you will never have to settle for a simplified experience or emulation when you can dive into a game whenever and wherever you may be. Make sure to learn a good 3 card strategy before you play.
Many sites and casinos will also offer free apps for you to download which will support their casino games output. Therefore, you won't even need to log into a main website unless you want to.
Even a few years ago, who would have believed that we would be playing live casino games on the go? It's great to be able to pick up a phone and play a game or two on the bus, at the beach or even at the office when the boss isn't looking – not that we endorse such behaviour!
Other Live Gaming
If you enjoy live poker, you might also be interested in other live gaming sites. If so, we would highly recommend having a look at these pages:
- Live casino sites
- Live Roulette online
- Live Blackjack games
- Online Live Baccarat
- Online live casinos with PayPal
Play Live Three Card Poker
Play live 3 card poker today at one of the many fantastic sites we have listed and lined up for you here.
With great deals, free play opportunities and plenty of chances for you to win big by bluffing a real dealer into submission, if you're already confident in your poker prowess, why not really put it to the test? Three card brag is a super speedy way to play poker at the casino table – and it's now available to play live online.
A-Z List Of Casino Games
We have compiled a full list of online casino games for you below and you will find some of your favourite games to play in March 2020:
- Baccarat Online Free
- Best Blackjack Sites
- Best Live Roulette Online UK
- Best Online Baccarat
- Best Online Craps Sites
- Best Poker Sites
- Best Roulette Sites
- Best Three Card Sites
- Free Online Blackjack
- Free Online Roulette
- Free Poker Sites
- Free Three Card Poker
- Live Baccarat
- Live Blackjack
- Live Poker
- Live Three Card Poker
- New Baccarat Sites
- New Blackjack Sites
- New Poker Sites
- New Roulette Sites
- New Three Card Sites
- Online Baccarat Sites
- Online Blackjack Sites
- Online Live Casino Sites
- Online Poker Sites
- Online Roulette Sites
- Online Three Card Brag
- VIP Casino Sites - High Roller Casinos
Each link takes you through to a page which lists the best casino brands to deposit with giving amazing welcome offer bonuses.
Table of Content
- Best Live 3 Card Poker Sites
- Live 3 Card Brag
- Live Three Card Brag
- Three Card Poker Live
- 3 Card Brag Live Casino
- Live Dealer Three Card Poker
- Other Live Gaming
- Play Live Three Card Poker
- A-Z List Of Casino Games


text:
- New England Spring Flower Show
- Spring Flowers in Boston
- Spring Flower Events in Boston
- Spring Flowers Bloom Calendar for Boston
- Where to See Spring Flowers in Bloom in Boston
- How to Save on Boston Hotels
- Plant Profile
- Care
- Multiplication
- Diseases
- Vermin
- Varieties
- New England Aster Plant Care: How To Grow New England Aster Plants
- New England Aster Flowers
- How to Grow New England Asters
- New England Aster Care
- Gardening How-to Articles
- Asters: Stars of the Show in Fall
- The Tall and the Small
- Good Company
New England Spring Flower Show
Since 1872, more than 5 1/2 acres of beautifully landscaped gardens, competitions, horticultural information and retail booths. Since 1872, more than 5 1/2 acres of beautifully landscaped gardens, competitions, horticultural information and retail booths. The Boston Flower & Garden Show is about inspiring, educating and motivating the region's gardeners. Whether for curb appeal, backyard, kitchen, indoor, rooftop or community gardens, this is where New England's green lovers go to discover new ideas while having fun with family and friends.
Colorful life-sized gardens and vibrant floral designs incorporate the newest design elements, examples of the popular and healthy food gardening trend ideas for adopting sustainable gardening practices and air-cleansing indoor plants. Included will be small-space gardens, homesteading hobbies, edibles-as-ornamentals and family and pet-friendly spaces for outdoor relaxation and entertaining.
This year's Show theme is "Garden Party: Celebrating Friends & Family". There's nothing more important than time spent connecting with the precious people and places in our lives! At this year's show, we'll celebrate outdoor living and interior plantscapes that inspire us to spend time with the ones we love. Explore plant families, including the beauty of "black sheep" and "everyone's favorites", as well as ways of connecting with each other through our love of nature and gardening.
Spring Flowers in Boston
Boston's spring flowers perfume the air as they burst into bloom in April.
The exuberant display of blossoms intensifies during May and June, and continues in more subdued hues until frost.
Look at the following photos to get a preview of what you can see if you visit Boston during spring and early summer.
Then, check out our recommendations for the best Boston locations for self-guided spring flower garden tours, plus everything you need to know about Boston garden shows, garden tours, festivals, and celebrations.
Spring Flower Events in Boston
Tulips and narcissus blooming in early April in Back Bay
Spring flower events grace the Boston Event Calendars for April and May. Several don't-miss highlights:
Art in Bloom – The Museum of Fine Arts transforms its galleries with exuberant flower arrangements based on the museum's masterpieces. Free museum admission if you have a Boston discount card.
Hidden Gardens of Beacon Hill Tour – For one day only, residents of Beacon Hill invite visitors behind their high brick walls, where unique hidden gardens delight their owners.
Lilac Sunday – What better way to spend Mother's Day than inhaling the exquisite perfume created by the Arnold Arboretum's extensive lilac collection, usually at its peak of bloom.
Boston Flower and Garden Show – Filled with magnificent display gardens, the Boston Garden Show held in March reminds us that spring really is right around the corner.
Find more garden tours in Boston and Cambridge
More Tours of Boston in the Spring
Spring Flowers Bloom Calendar for Boston
You'll see dates for most of the flower photos on this page – but keep in mind that bloom times differ a little each year, and sometimes a lot.
Here is when you can typically expect specific flowers to bloom during spring and early summer in Boston
Late March – Mid-April:
- Crocus and other small bulbs
- Daffodils and early tulips
- Buds and perhaps a few early blossoms on magnolias and other flowering trees
Mid-April – Early May
- Magnolias and cherry trees in full bloom
- Tulips and late daffodils
- Azaleas
Early May – Early June
- Rhododendrons
- Lilacs
- Peonies
- Roses – the classic sign of summer!
Where to See Spring Flowers in Bloom in Boston
Pink tulips in Boston's Public Garden in mid-April
Although you can see plenty of blooming flowers throughout Boston during April, May, and early June, several neighborhoods and gardens offer especially gorgeous viewing.
Here are our recommendations for central neighborhoods where you can go for self-guided spring flower tours:
Back Bay Spring Flower Displays
Back Bay tops our list for spectacular displays of spring flowers for one reason: the dazzling magnolia trees, especially along Commonwealth Ave, Marlborough Street, and Beacon Street. You'll see huge saucer magnolias in hues ranging from pearly pink to fuchsia to deep purple mixed in with ethereal star magnolias, and other types of flowering magnolias as well.
Saucer magnolias along Marlborough Street in mid-May
Buds start opening in early April, and the display is well underway by Boston Marathon weekend. When the weather cooperates (no early searing heat, no thunderstorms with driving hail, no tearing winds), you can still see magnolias in bloom through early May.
The front gardens of many Victorian brownstones in Back Bay feature plenty of daffodils, tulips, other spring-flowering bulbs such as giant alliums, and perennials.
Even more spectacular, though, are the rhododendrons, peonies, and early roses appearing throughout Back Bay in May and into June.
Rhododendrons blooming in Boston's Back Bay neighborhood in late May
The Esplanade
Flowering cherry trees in April along the Esplanade
Cherry trees planted along Boston's Esplanade burst into bloom in April, and turn this lovely park next to the Charles River into an enchanted garden.
Sadly, they don't last long but are worth the effort to see. Every year is different, but mid-to-late April is usually a good bet.
You'll find the highest concentration of cherry trees in the section of the Esplanade bordering Back Bay, roughly between the Fiedler Footbridge (off Arlington Street) and the Mass Ave access ramp.
Kelleher Rose Garden
Roses in Kelleher Rose Garden in mid-June
Most magnificent in June, with blooms continuing from May through Frost.
More about the Kelleher Rose Garden located near the Victory Gardens in Boston's Fenway neighborhood, just a couple of blocks from Fenway Park.
Boston's Public Garden
White parrot tulips blooming in late April in the Public Garden
Located next to Back Bay (check the Boston Sightseeing Map to quickly see locations of all these neighborhoods), Boston's Victorian-era Public Garden features winding paths and lots of small but formal planting areas.
Spring flowers on display vary somewhat each year, but always include tulips and other spring-flowering bulbs and annuals such as pansies during April and May. In keeping with the Victorian character, you'll usually see lots of unusual sub-tropical types of plants here as well – apparently these were popular during Victorian times.
In addition to flowers, spring foliage in the Public Garden is also spectacular, especially the chartreuse-colored weeping willows surrounding the lagoon. The best way to enjoy close-up views of the willow foliage is by taking a swan boat ride. The swan boats return in mid-April, so the timing is perfect.
The South End
Magnolias in bloom in the South End near the Southwest Corridor
Much of the South End is shady, and gardens tend to be tiny – but that doesn't stop South Enders from planting spectacular container gardens. Walk down Waltham Street and the side streets intersecting with it, and you'll see some wonderful examples. Combine this stroll with a visit to SoWa Open Markets, opening in early May, for a perfect Sunday afternoon in this trendy Boston neighborhood.
The Southwest Corridor Park, lined with community gardens, is another South End location where you can count on seeing plenty of brilliant spring flower displays. From Back Bay station, walk down Dartmouth Street going south. Almost immediately, you'll see the Southwest Corridor to your right.
For the best views of South End gardens, go on the annual South End Garden Tour.
Rose Kennedy Greenway
Spring flowers blooming in May along an edge of the Greenway near Dewey Square
The garden sections of the Rose Kennedy Greenway overflow with lovely spring flowers.
Across from the North End, you'll find a broad stretch of daffodils blooming from about mid-April until early May, when daylilies take over. That's where the gorgeous yellow magnolia trees shown in the photo gallery are located.
As you walk south, you'll pass other areas with tulips and more daffodils. Most spectacular, though, are the Chinese Gardens near South Station and Chinatown. Starting in about mid-May, peonies and rhododendrons fill this area with color and fragrance, and contrast wonderfully with the new pale-green bamboo shoots
If you're visiting in late May or early June, the best place to begin your Greenway tour is not on the Greenway itself, but a few steps away at the Rose Kennedy Memorial Garden, located near the southwestern edge of Christopher Columbus Park just north of the Boston Marriott Long Wharf Hotel. Roses in this lovely oasis bloom from late May through frost, with especially spectacular flowers during June.
The North End
Magnolias blooming in late April in the "Peace Garden" courtyard in front of Saint Leonard's Church in Boston's North End
In April, look for spectacular cherry trees in full bloom tucked in pockets between the North End's densely spaced buildings.
The courtyard in front of Saint Leonard's Church on Hanover Street is especially beautiful when the trees are in full bloom.
How to Save on Boston Hotels
Check out all our tips on how to find discounts, deals, and promo codes for Boston hotels. Whether you're looking for bargain accommodations or want to pay less for luxury, we'll show you How to Save on Hotels in Boston.
More about how to save on Boston hotels
The numerous small flowers with their colorful, radically arranged petals are responsible for the fact that the white wood aster belongs to the most attractive late blooms in Central Europe. In late summer and autumn many flowers cover the lush green shrub. Choosing the right location and taking care of it according to the following instructions will ensure that you can enjoy the flowers for several months.
Plant Profile
- family: asters (Asteraceae)
- species: asters (asters)
- origin: Europe, Asia, Africa
- perennial, mostly bushy shrub
- growth height: depending on variety 20 to 150 cm
- restant, perennial plant
- flowering period: August to October, rarely until November
- flower color: white, yellow, orange, pink, red, purple, blue
Only when most of the ornamental plants have already faded, the colorful white wood asters have their great appearance. On the small shrubs, numerous colorful and densely growing flowers open up between August and October, which make the plant with a sea of blossoms a real sight. Asters have a very good effect both in the plot, as well as in the stone garden or in buckets. They are also popular as cut flowers in autumn bouquets. So that you have a long time to enjoy the colorful perennial, you should follow the instructions carefully.
In addition to the viewer, insects are also happy about the blossoming splendor: the late-flowering asters serve as a food source for bees and butterflies in the autumn.
White wood asters are comparatively robust, but somewhat more demanding than China asters. With a few measures and a regular care, diseases and pests can be avoided, so that the garden plant thrives and intensively blossoms for many years.
A sunny location is best suited for white wood asters. In the morning and afternoon sun they grow optimally and form a lot of flowers. If possible, however, the shrub plants should not stand in the hot midday sun, as the flowers are not so tolerant and therefore the flowering time can shorten. A few varieties can also be planted in a semi-shady location.
The white wood aster grows optimally in a loose, nutrient-rich, humusible and permeable substrate. Normal garden earth is usually sufficient. If the soil is too sandy, however, it should be mixed with compost. Under too tight ground you can mix sand and / or compost to loosen it and improve its permeability.
In spring or autumn, asters are placed in the ground. A minimum distance of 30 cm should be maintained between the individual perennials. This allows the air to circulate well, resulting in a reduced risk of disease and pest infestation. Young plants, which are still growing strongly, should be put somewhat further. A distance of 50 cm to 80 cm is recommended.
The Aster does not tolerate permanent drought. The soil should always be kept fresh to damp, but without the formation of frost. If it rains too little, the plant must therefore be regularly watered in the summer. Pour the shrub from below and close to the ground so that the leaves do not become moist. White wood asters are prone to mildew, which particularly likes moist leaves.
In order to stimulate the growth and favor a lush bloom, the aster should be fertilized once in the spring. For this purpose, for example, compost can be raked into the ground. Alternatively complete fertilizer is suitable.
Withered flower heads can be carefully removed. This favors the growth of new flowers. If the plant is completely faded, it can be cut back in the upper third. Subsequently, the complete retreat takes place either in late autumn or early spring. All branches and twigs are cut back so that only the base remains.
The white wood aster can be breeded in different ways.
Asters are most easily breeded by division. Every two to four years, a plant should be divided into two or more new plants that you plant separately from each other at a new location. This leads to a rejuvenation, which preserves the flowering ability and strengthens the plant. The division should be carried out after flowering in the late autumn or alternatively at the beginning of the spring. For this, the aster is divided with a sharp and clean knife at the root.
To breed white wood asters over cuttings, first cut a shoot from the mother plant. This should be about ten centimeters long. Remove the foliage in the lower third and insert the shoot into a pot with a potting compost or a mixture of garden soil and sand. As a high humidity favors the growth, you should put a bag or something similar as a hood over the pot.
White wood asters are sown outside in spring. The seeds germinate at temperatures between 18 and 21 degrees Celsius within two to three weeks. If you want to sow asters in summer, autumn or winter, you should do this in a bucket in the house or in the greenhouse. Again, a temperature between 18 and 21 degrees Celsius should be considered. The pre-grown plants can then later be placed outside.
White wood asters are perennial and can overwinter in the bed. In order to protect the roots from frost, the soil can be covered with an additional compost layer around the plant for safety.
The most common disease affecting the perennials is the aster-withering. The following symptoms indicate an attack.
- the leaves suddenly hang limply, dry up and finally die – no matter how much the aster is watered
- the stalks turn brown
- a reddish mucus occurs
The disease is caused by fungus Verticillium, which blocks the plant and prevents it from passing on water. Infested shrubs are no longer to be saved and have to be dug generously as quickly as possible and disposed of in the organic waste collection bin. As the perennial fungals are embedded in the soil, the diseased plant must not be composted. After the aster has been removed, the earth should be mixed with calcium nitrogen. At least eight years later, white wood asters can be planted again at the affected site. Since the fungi only attack asters, other plants can be used here.
In addition, you can use these measures to prevent the aster-withering:
- use stained see
- plant the asters in sterile soil
- change the location of the plants every few years
- divide each aster every three to four years
- use resistant varieties. They can be recognized by the indication "wilted-free"
Powdery mildew
Care failures often lead to an infestation with powdery mildew. The main threatened are asters, which are constantly moist. The disease manifests itself through various symptoms.
- on the top of the leaf are small white or gray spots
- from the spots develops a mealy covering, which covers leaves, shoots, flowers and buds
- the affected plant parts become brown and fall off
- the plant is more and more stunted
The aster can be saved if the infestation is detected in time. All affected plant parts must be cut off and disposed of in organic waste bin. Subsequently, the plant should be sprayed thoroughly with a fungicide, which acts against mildew.
Preventive measures reduce the risk of infestation:
- the plants should be poured close to the ground and not from above, so that the leaves do not get wet
- those who planted several white wood asters should not put them too close together, as a result, the individual plants are better ventilated and rain, dew and water from other sources dries better
- Asters must not be fertilized too much
Asters are mainly affected by diseases, less by pests. If a pest spreads on the plant, it is usually the aphid like on many other plants. Rinse the small insects with a stinging nettle or soapy solution. The affected plant should be sprayed several times at intervals of two to three days from all sides. Once no aphids are visible, you can complete the treatment.
The white wood aster is a speciose plant, which differs mainly by size, color of the petals and sensitivity. The many varieties can be classified in three different ways.
Bushy aster (Aster dumosus)
The aster dumosus is the lowest type and spreads out strongly to the side. A shrub is between 20 cm and 50 cm high, which is why it is especially suitable for hardwood or as a bedding. It is also a popular cemetery plant. The Aster dumosus produces a particularly large quantity of small flowers.
Among the best known varieties of aster dumosus are:
- the variety bobby-dazzler blooms in the intense Violett and becomes up to 25 cm high
- the aster dumosus rosedwarf develops pink flowers and also reaches a maximum height of 25 cm
- pink to lilac flowers grow on the variety autumn greetings from the Bresserhof, which grows up to 40 cm
- the small white flower of the sort snowpillow reminds of camomile flowers, this aster dumosus reaches a height of maximum 20 cm
New York aster (Aster novi-belgii)
The New York aster differs mainly in its size from the aster dumosus: it achieves a growth height of 50 cm to 150 cm. Larger plants should be supported so that they do not bend. As the name suggests, this aster has smooth leaves. The Aster novi-belgii is more sensitive to diseases than their relatives.
The most popular varieties of this type are:
- the sort beacon is lit in bright pink. It is up to 80 cm tall
- the New York aster Royal Ruby has a full, purple-colored flower and grows up to 60 cm high
- the sort rose quartz has unusually narrow petals in tender pink and is up to 110 cm high
- the blue-violett-blossoming sort beauty of Dietlikon reaches a size of up to 150 cm
New England aster (Aster novae-angliae)
Also up to 150 cm can be the different varieties of the New England aster. This species is distinguished by its hairy leaves. In addition, their flowers close at night and in bad weather. New England asters are more resistant to mildew than other species. However, they tend to discard their leaves in the lower part during flowering. Therefore, the aster novae-angliae often looks bare. However, those who planted lower plants around this species can conceal this easily.
Among the important varieties of New England are:
- the sort Purple Dome has purple flowers and reaches a height of 70 cm
- the Aster novae-angliae Alma Pötschke blooms pink and is up to a meter high
- the only white flowering New England aster is the sort autumn-snow, which grows up to 140 cm
- Ruby treasure is the strong ruby red flowering variety, which is up to 150 cm high
New England Aster Plant Care: How To Grow New England Aster Plants
Looking for a burst of color for your fall garden? The New England aster plant (Aster novi-angliae) is an easy to care for perennial, blooming from August through October. Most North American gardeners can learn how to grow New England aster. Once established in the garden, New England aster care is extremely easy. Keep reading for more information on growing New England asters.
New England Aster Flowers
A wildflower member of the Asteraceae family and native to the eastern and central United States, New England aster flowers are generally found in meadows and other moist, well draining soils. The New England aster plant has medium green to gray-green foliage with an odor somewhat reminiscent of turpentine, when crushed.
Don't let the unpleasant aroma put you off, however. This plant provides stunning rose to lilac or deep purple blooms in mass plantings within native species gardens, low-lying areas, along roadsides and around tree lines. The brilliant blooms make great cut flowers, and are longer lasting in water than its cousin the New York aster (A. novi belgi). The floral display provides color long into the waning days of summer.
Other varieties of New England aster flowers are available for the home garden as well and
will provide additional color. These include:
- 'Alma Potschke' produces 3 ½ foot tall plants with vibrant pink blooms.
- 'Barr's Pink' blooms are rose-colored, semi-double flowers on a 3 ½ foot tall plant.
- 'Harrington's Pink' lights the garden with 4 foot tall pink blossoms.
- 'Hella Lacy' is a 3 to 4 foot tall plant with dark purple blooms.
- 'Honeysong Pink' has yellow centered pink flowers on 3 ½ foot tall plants.
- 'September Beauty' blooms a deep red on 3 ½ foot tall plants.
- 'September Ruby' flowers are rosy-red atop 3 to 4 foot tall plants.
How to Grow New England Asters
Growing New England asters, as with other aster plants, is easy. This particular aster variety prefers full to partial sun in USDA plant hardiness zones 4-8.
Propagate by seed or division when growing New England asters. Although a bit more difficult to grow from seed, it is well worth the effort. Surface sow in the spring in an area of rich, moist soil as these plants tend to wilt in poorly drained clay. The New England aster will germinate in 21 to 45 days at a soil temperature of 65-75 F. (8-24 C.).
These late summer through early fall bloomers spread 2 to 4 feet with a height of 1 to 6 feet. When planting make sure to provide good air circulation, keeping in mind the large spreading area.
New England Aster Care
New England aster care is moderate. Just divide in fall and fertilize and cut back in spring. These daisy-like flowering plants should be divided every two to three years in late fall to promote vigorous specimens.
The taller varieties, such as the 4-foot tall bluish-purple 'Treasurer' or the nearly 5-foot tall purple-red 'Lyle End Beauty,' usually require staking. Pinch plants early in the season to get a lower growing and bushier plant or choose a dwarf variety like 'Red Star' (1 to 1 ½ feet with deep rosy flowers) or the aptly named 'Purple Dome.'
New England aster flowers may also self seed in optimal conditions. Be aware of this self-sowing when growing New England asters. To avoid self-seeding in the garden, cut back after blooming.
This non-invasive beauty is fairly disease and insect resistant; however, it may be prone to powdery mildew.
Keep soil moist as mentioned above and prepare to enjoy this hardy and bountiful perennial for years to come.
By Jonathan Chesler
Assistant to the Head Gardener
As summer hits its high arc and the days grow technically but as yet imperceptibly shorter, Northeastern gardens are in full flush and bloom. Pick-your-own produce places pop up and roadside farm stands fill out with signs for 'Native Corn' and 'Native Tomatoes.' Despite the horticultural inaccuracy found on those placards and in other cases, it's noteworthy that a plant's native status is emphasized as an important selling point. True, while everything is native to somewhere, for our purposes, native plants are those that have been found in the Northeast (New England) from pre-Colombian times.
The white-flowering Coneflower, Echinacea purpurea 'White Swan,' and Rudbeckia fulgida sullivantii 'Goldsturm' are both improved natives, and they're both popular with pollinators.
So why the interest and excitement over natives? Firstly, native plants ask for few resources upon seeding or planting them, and they also give back in abundance. As these plants have co-evolved with native butterflies, moths, birds and the like, they are recognized as sources of food, and good food at that. It's not by coincidence that White Flower Farm's Butterfly Magnet Collection, Monarch Butterfly Collection, and Pollinator Garden for Sun heavily favor native cultivars; e.g. Liatris, Phlox, Echinacea, Milkweed, Agastache, and Coreopsis (in no particular order).
Aster 'Monch,' an improved variety of our native Aster, begins blooming earlier than most of its relatives. The lavender flowers arrive in our area around July, and they keep on coming until frost.
When properly placed and established, native plants are vigorous players that usually outperform newcomers when the vagaries of nature throw drought, inundation, disease, and predatory herbivores their way. Not to say that they cannot be affected and even succumb to the aforementioned, but they often can overcome such problems with minimal care. This leads us to the next point: native plants generally don't need as much water, fertilization and disease control as non-natives. This leaves you more time to fuss over other areas of the garden, or perhaps a chance to sit back and enjoy!
Finally, despite increasing popularity, natives and native cultivars are uncommon enough to elicit surprise, yet they're entirely familiar and fitting in our gardens. No matter what kind of environmental conditions you have in your garden, or what kind of color or effect you're looking for, you're sure to find a native that excels in one or more areas. Dry or wet, shady or sunny, small or expansive — there are plenty of choices that are horticulturally interesting in leaf, form or flower. What follows here are some native highlights best seen in fall, before New England's lakes and ponds release their stored summer heat and before morning mist and leaf peepers displace the snowbirds heading south.
Lonicera sempervirens 'Major Wheeler' is an improved variety of the straight Honeysuckle species, our native Lonicera sempervirens. Hummingbirds love the tubular flowers on this vine. You'll love the color that persists from summer into fall.
While correlation does not imply causation, native fall flowers seem to hit their stride just as 'Back to Skool' advertisements begin to appear. Liatris, Coreopsis, and Monarda (Bee Balm) recede as Trumpet Honeysuckle, Autumn Phlox and Ox-eye Daisies continue their earlier summer shows into early autumn's prime-time. Echinacea, Rudbeckia and Asters are in full effect. As vacations end and grumbling begins, optimistically bright Black-eyed Susans are true pick-me-ups and are as quintessentially New England as clam chowdah and apple pie.
New York Ironweed in flower at the site of the former Project Native. The tag on the butterfly is part of a study monitoring their progress in the wild. / Photo by Jonathan Chesler
The Goldenrods flower, as does Vernonia novaboracensis, New York Ironweed. White Flower Farm offers the Ironweed cultivar 'Iron Butterfly,' which tops out at about 3', far below the impressive 6-8' potential of the straight species, making it far more practical scale-wise for most gardens. It's a strong favorite of Monarch butterflies, and the persistent seed heads fade to a rust color in the fall, giving it the common name. The seed heads are treasured by birds in the winter.
Part of the Mariachi(TM) series of compact Heleniums, 'Fuego' is an improved form of our native Helenium autumnale. It adds vibrant late-season color to the garden.
Another spectacular fall flower is Helenium autumnale, which is also called Dog-tooth Daisy or Sneezeweed. Beyond the straight species' pure orange-yellow are brighter yellows and reds and oranges best found in the Mariachi™ series, which is also offered and grown here at White Flower Farm. Chelone glabra, Turtlehead, can be a late-to-the-party, white- or pink-flowered, deep green-leafed shade-tolerant plant, which, contrary to much of what's written, can handle sun, if provided with enough water.
Eragrostis spectabilis, Purple Love Grass, appears at this time as well, along roadsides and in our new Native Garden designed by Head Gardener Cheryl Whalen. The light and feathery, relatively low seed heads are more of a 1980's neon pink than purple, but semantics notwithstanding, and as the Latin implies, it's a spectacle not to be missed.
Our native Viburnum acerifolium, or Maple-leaved Viburnum, produces lacy white blossoms in summer followed by richly colored foliage in the fall. / Photo courtesy of Missouri Botanical GardensMaple-leaf Viburnum puts on its autumn show. The berries are inedible to humans but they're favored by birds. / Photo by Jonathan Chesler
In addition to flowers, shrubs small and large come into their own just as signs for New England's Fall Fairs start appearing by roadsides, framed by the aforementioned Eragrostis. Red or black, you win either way with Chokecherry roulette. The fiery red foliage is a feast for the human eye, and for many a hungry bird to boot. And while most people fend off angry birds to protect their blueberry crop, Blueberry bushes both high and low are surprisingly undervalued for their foliage, which I find even more attractive than the Chokecherries, and far superior to the invasive, thornily ornery Berberis thunbergii, more commonly known as Japanese Barberry. If you prefer the hot pink fall foliage of Barberry to the redder Blueberry, there is still a native answer – Viburnum acerifolium, Maple-leaved Viburnum. This understory shrub is eye-catching and, like the Chokecherries, its berries are inedible for humans but delicious to our avian companions.
Amsonia hubrichtii, its foliage glowing yellow in autumn, is a Southeastern native and a cousin of our Northeastern native, Amsonia tabernaemontana.
In addition to brilliant colors, there is a wide variety of natives that offers interesting foliage textures to Northeast gardeners. While many of the above have small leaves and the Amsonias in particular take fine texture quite seriously, Hydrangea quercifolia, the Oak-leaf Hydrangea, and Rubus odoratus, or Flowering Raspberry, have broad leaves and coarse texture. Both need a fair amount of room, and they tolerate or prefer light to part shade. Shade will reduce bloom size and number, but if that's not the goal, they can fill in space very nicely. I have an Oak-leaf Hydrangea that was slammed into a lightly shaded corner quickly before the frost two years ago, but it has responded so well in form and flower that the most temporary solution became the most permanent.
Pretty Clethra 'Ruby Spice' adds beauty and fragrance to summer gardens. The dark green foliage turns yellow in autumn. It's an improved form of the native Clethra alnifolia.
The Oak-leaf Hydrangea's spectacular orange, scarlet and purple extends its seasonal interest and contrasts the lemon yellow of the Flowering Raspberry. In addition to the red and pink fall foliage described above, Lindera benzoin or Spicebush, Clethra alnifolia or Sweet Pepperbush, and Amsonia tabernaemontana or Bluestar, provide attractive yellows to brighten the fall color palette.
Rudbeckia 'Goldsturm' is a standout in the late summer border amid violet pink Phlox, paler pink Agastache (foreground right), the dried flower heads of Drumstick Allium (left), and globe-shaped Allium (foreground right), and Ornamental Grass.
In this New-York-minute scramble through the ancient Adirondacks, past Congregationalist churches, "Native Corn" farm stands and "Pick Your Own" pastures, I hope you've sensed the wide variety of available native plant material, whether you aim for sun or shade, big or small, flower, leaf color or shape, or edibility for yourselves or for friendly fauna. So explore, and indeed, pick your own!
Gardening How-to Articles
Asters: Stars of the Show in Fall
By Stephanie Cohen | September 1, 2001
The onset of fall can be a time of mixed emotions for many of us gardeners. As trees and shrubs begin to clothe themselves in showy autumnal colors—burnished oranges, glowing reds, buttery yellows, overtones of bronze—our perennial borders take on a somewhat sad, lackluster appearance.
Indeed, it's often the case that when the dog days of July arrive, a mild horticultural despair sets in and dissuades us from making any further trips to the nursery. If we do decide to go, it's usually to shop for the easy quick fix: mums! Typically, we'll buy legions of brightly colored chrysanthemums to camouflage the spots where faint-hearted perennials have keeled over or where annuals are just about spent.
But there's an alternative to the chrysanthemum solution that provides, in my opinion, a happier denouement to our usual tales of gardening woe. Asters! Our hardy, sun-loving native asters cruise through the summer swelter and build to a crescendo of late-season blooms. What's more, their primarily blue-violet flower tones work in cool, subtle contrast to the fiery fall landscape at large.
There are hundreds of species with the common name of aster. They were once considered part of the huge Aster genus, but North American species were reclassified into several other genera in the 1990's after research showed that they were not closely related to Eurasian species. All aster species belong, along with zinnias, dahlias, mums, and other daisy-faced beauties, to the Asteraceae, the largest of the flowering-plant families. Since wild asters generally grow to about 5 or 6 feet tall and have "weedy-looking" foliage, gardeners in the United States have been slow to embrace them. This is not the case in England and Germany, where breeders have been creating more compact and garden-friendly varieties since the 1890s.
Cultivated asters are now available in a myriad of different shades: from the typical blues, pinks, and purples to whites and reds. Most species bloom in the fall. Pinch them back around mid-July and they'll produce a profusion of 1- to 2-inch-wide, star-shaped flowers. (Those of you who are intimate with night skies and heavenly bodies will know that aster is the Greek word for "star.")
The Tall and the Small
Let's begin with Symphyotrichum novae-angliae (zones 4 to 8), the wonderful New England aster. This classic wildflower of our open sunny spaces grows to five feet in height and bears violet-purple flowers with yellow centers from late summer to mid-autumn. Its strong stem makes it perfect for flower arrangements.
The New England aster has furnished us with a wide variety of cultivars. Like the species plant, they all flourish in full sun and good garden loam. The taller selections, if you forget to pinch them, may need staking. 'Alma Potschke' grows between 3 and 4 feet tall, with bright rosy red flowers. If you're a timid soul, you might need sunglasses when you gaze at this hot aster.
I have an affinity for short plants, so my favorite is 'Purple Dome'. It grows to between 18 and 24 inches tall and, come early fall, is absolutely drenched in vivid purple flowers. Many asters are prone to mildew and leaf diseases and can wind up, excuse the expression, "with bare bottoms." But 'Purple Dome' is so close to the ground that any damage it might sustain is unnoticeable.
More: Beautiful native aster species growing at Brooklyn Botanic Garden.
Symphyotrichum novi-belgii, the New York aster (zones 4 to 8), grows to four feet. Its stems are more slender than those of the New England aster, but it has similar flower color and cultivation needs. English gardeners refer to it as the Michaelmas daisy since it's always in bloom during the feast of Saint Michael (September 29th). Getrude Jekyll, the doyenne of perennial garden design, loved these flowers so much that she used them to compose an entire border.
The New York aster's long list of cultivars includes 'Mount Everest', which grows to 3 feet and is covered in lovely white flowers for a few weeks. 'Lady-in-Blue' is a recent introduction, just 12 inches tall, with lovely medium-blue flowers. 'Nesthäkchen' is 18 inches tall and compact, with really striking pinkish red flowers—I'm fond of this one not only for its color but also its resistance to mildew. 'Professor Kippenberg' is an old-fashioned cultivar; at 12 inches, with attractive lavender semi-double flowers, it makes a definite statement for a short plant.
The new Woods series offers 8-inch dwarf asters in pink, purple, and blue that are excellent for the front of the fall border. 'Royal Ruby' and 'Royal Velvet' are taller cultivars, growing to between 24 and 30 inches. They offer, respectively, a semi-double ruby color and a baronial violet-purple. Finally, another British-sounding cultivar is 'Winston Churchill'. It is only 2 to 3 inches tall with very deep red flowers.
'Bluebird', a cultivar of Symphyotrichum laeve, the smooth aster (zones 4 to 8), is a personal favorite of mine in the category of tall asters. Violet-blue yellow-centered flowers and attractive blue-green foliage make this 3-foot aster one of the highlights of my fall border. I like to combine 'Bluebird' with Solidago rugosa 'Fireworks', a lovely 3-foot compact goldenrod with great, arching sprays of golden flowers.
A little-known aster is Symphyotrichum oblongifolius, which can tolerate a fairly dry environment. The 2-foot-tall cultivar 'Raydon's Favorite' flourishes in full sun and well-drained soil. Its blue-purple daisy flowers explode in early fall above fragrant foliage.
'Prince', a cultivar of Symphyotrichum lateriflorus or calico aster, like the pop star of the same name, dares to be different. At 3 feet tall, it has white daisy flowers with contrasting dark purple foliage. This foliage may turn green in very hot weather, but if given light shade in the afternoon can keep its unusual color. 'Prince' likes a moist, moderately fertile soil (zones 4 to 8).
Ampelaster carolinianus), the climbing aster, flourishes from zones 6 to 9. Come springtime, it already looks rather tall and spindly. As the seasons progress, it can reach a height of up to 12 feet. Ampeleaster carolinianus prefers full sun and fertile soil, and produces arching stems with pink to purple flowers in October. It looks marvelous sprawling along a fence or trellis.
Eurybia divaricata, the white wood aster (zones 4 to 8), is perfect for the shade garden. It grows from 12 to 18 inches and, in August, produces tiny white daisies with yellow centers atop heart-shaped leaves. It works great in light shade with good air circulation, but prefers morning sun. The caveat is that, if it likes your garden, it will spread rapidly. So thin it out in spring if you'd like other things to grow as well.
Good Company
To take full advantage of the diversity of asters—short, medium, tall, and climbing—choose a worthwhile companion plant. I've already mentioned goldenrod. Try, too, one of the wonderful fall-blooming alliums, such as Allium virgunculae, whose pink star-shaped flower clusters appear in October.
Another interesting combination plant is Amsonia hubrichtii (Arkansas amsonia), whose feathery green foliage turns a handsome buttery yellow come autumn.
Some of the best partners for fall are the late great grasses like the Panicum species (switch grasses), whose autumnal colors echo those of the surrounding trees and shrubs. 'Heavy Metal' has metallic blue leaves that turn yellow to buff. Its airy plumes are off-white. The foliage of 'Haense Herms' turns scarlet in fall. 'Dallas Blue' also gets great fall color.
Asters even make great companions for your chrysanthemums, if you find it too hard to let them go.
Nursery Sources:
Niche Gardens
1111 Dawson Road
Chapel Hill, NC 27516
Phone: (919) 967-0078
Roslyn Nursery
211 Burrs Lane
Dix Hills, NY 11746
Phone: (631) 643-9347
WE-DU Nurseries
2055 Polly Spout Road
Marion, NC 28752
Phone: (828) 738-8300
Prairie Nursery
P.O. Box 306
Westfield, WI 53964
Phone: (800) 476-9453
Heronswood Nursery
7530 NE 288th Street
Kingston, Washington 98346
Phone: (360) 297-4172
Stephanie Cohen teaches at Temple University, Ambler and is founding director of the arboretum there. She is that author of The Perennial Gardener's Design Primer.


text:
Category Archives: Minnesota
First Dog-Cousin, Once Removed
Clark and Tessie came immediately to the back screen door, already vocalizing their hunger. No Lewis.
A Sign From God
"Meeting you was a divine encounter. I'm living on trust, too." Jacob grinned, as if my existence validated his life.
What's in a Name
But, during the Advent season, I remember why I like my name.
Like Riding A Bike
I could feel the wind teasing my pigtails. I was positively gliding. Then I glanced backward, realized my dad was no longer behind me, and promptly fell off the bike.


text:
The Victorian Government has announced new measures to contain the spread of coronavirus (COVID-19). They come into force at midnight
tonight 25 March 2020.
They have already ordered the closure of hotels, pubs and clubs (excluding bottle shops within those venues), casinos, cinema, nightclub, entertainment venues, gyms and indoor sporting centres.
There are now further closures of non-essential businesses, limitations on certain activities, and closure of a range of venues, attractions and facilities where large numbers of people would otherwise be in close proximity. Read More…


text:
Hello from Gold Coast in Australia
Sexy Single Searching I Want Sex Tonight Horney Lady Want Phone Sex Dating
It is full of special offers to save you money as well as comprehensive range of Gold Coast maps to help you find your way around all we have to offer! Be thrilled with excitement!
|Relationship Status:
|Looking Sexual Encounters
|Gold Coast
|Bright red
|Relation Type:
|Women Sluts Officer Looking For Custom Tailoring
Views: 5517
See Second Working Holiday visa applications — evidence of payment for specified work for more information. How to find specified work Applicants can find specified work vacancies in the same way as they would find other job vacancies, such as through employment pages in newspapers, the Internet and job placement Caringbah bikini sex providers.
Sign Up. Archived from the original on 13 October France My name Austrwlia Odile, I Hot Goulburn college girls a sculptor living and working in a magnificent medieval castle in Auwtralia beautiful French garrigue Good Provence at the Pay via a grant through Donors Choose Professional Development.
See the section on Regional Areas below to check the postcode list of He,lo regional areas. Retrieved 26 July Australian Business NUmber: The Australian business number ABN is a unique digit identifier that makes it easier for businesses and all levels Hello from Gold Coast in Australia government to interact.
On our last day we wanted to Hrllo a nice view of Brisbane so took a ferry to the Gateway Bridge but once we got there in the heat it was too Heplo to walk to. Seafood also stars at newly remodeled izakaya-style bar Yamageninside the Hello from Gold Coast in Australia cool QT hotel. Archived from the original on 5 January Archived from the original on 23 June Listen Older women seeking younger men for sex in Australia to questions and answer them honestly and competently.
Archived from the original on 4 September There are a number of libraries located on the Gold Coast. Note: Secondary processing of animal Hello from Gold Coast in Australia, such as small goods processing and retail butchery is not eligible. Forgot account? Retrieved 23 January International Railway Journal.
Help, enjoy and share in our little paradise Ciast Panama. Turner Broadcasting System, Inc.
How Australia's Gold Coast reinvented itself
The Gold Coast is the Hot Canning Vale lesbian home of a number of Indigenous clans of the Yugambeh people, including the Kombumerri, Bullongin, and Tulgi-gi-gin clans. A minimum wage. Services are provided to interstate capitals and major cities as well as to major New Zealand cities, Malaysia, Japan and Singapore.
The Little Nerang Dam which feeds into Hinze Dam can supplement part Hello from Gold Coast in Australia the city area's water needs, and both are managed by the city council directorate Gold Coast Water. Evidence of an international drivers license is required.
Indigenous Australians accounted for 1. Retrieved 19 December Init will be held on 4—5 July and the 37th Gold Coast Airport Marathon is set Hel,o motivate and challenge more than Hello from Gold Coast in Australia, people of all ages and abilities.
HelloLitCon Gold Coast, Australia
Hello Australia. Or simply lace up your hiking boots and trek one of the routes Hellk Lamington or Springbrook National Parks -- both easy day trips from the city. Construction work Coxst be vital in helping regional disaster zones, such as those affected by flood or bushfire, to rebuild and recover from disaster. Contacting third parties to verify the claims of applicants for second Working Holiday visas will now be a Coxst component of second Working Holiday visa application assessments.
Must be available weekends and own transport essential.
We live in Fore river massage Carlingford four-bedroom double uAstralia home in a gated community. Cover letters Your cover letter is an important component of your application and should: introduce you to the employer identify the position Jas escorts Southport are applying for convey your Hello from Gold Coast in Australia for the position highlight the stand-out qualities that make you a great candidate inspire the reader to continue reading your application frkm letters are not a summary of your resume.
It is the second drom public vantage point in the southern Hellk after the Eureka Tower in Melbourne. Hel,o from the original on 8 October Auxtralia❶Archived from the original on 30 October Between the suburbs of Surfers Paradise and neighboring Broadbeach to the south, cranes are busily erecting new hotels and cloud-scraping towers.
If West african currency Melbourne have any questions about payment, purchase orders, or invoices, please ask at kelsey helloliteracy.
Hello from sunny Gold Coast Queensland, Australia.
Estimated resident population, 30 June Setting up veg garden and finishing a house in Ireland. Hours expected Maximum 4 hours a day, 5 days a week. Write the grant and Donors Choose will pay Hello Literacy on your behalf. The technicolored Athletes' Village for the Commonwealth Games.
The ability to multi-task at a fast pace; Excellent communication skills; Willing to learn and can work under pressure in a team environment. Retrieved Spa sex Caringbah April January Must have frkm means of transport.|What's this? We are a family of.
My husband works in waste management and works away in Melbourne a lot and I study teaching full-time and work relief Austrlaia a Teaching Assistant. We live in Hope Island which is on the northern end of the Gold Coast minutes by car to central Surfers Paradise and 40 minutes drive to Brisbane. We Austra,ia in a resort surrounded by water and golf courses and an early morning Akstralia afternoon walk will get you acquainted with iin local kangaroos.
The beaches are a minute drive away and Mount Tambourine Coaet approx 30 mins.
Gold Coast, Queensland
You will have access to a car Jeep Cherokee to explore the Gold Coast. For this reason, we will Rsvp singles events Armidale someone who is flexible as sometimes I have no study or work and I will do school pick-ups, homework and dinner and you will have days off to Ahstralia to explore.
We can negotiate. If you work or study, that is ok.
Gold Coast, Queensland - Wikipedia
We live in a four-bedroom double story home in a gated community. Coxst have a spare bedroom with a queen-size bed and a spare bathroom, however separate toilet shared with the children.
Meals included.]Hello from sunny Queensland, Australia. Country.
Hello from sunny Gold Coast Queensland, Australia.
Australia. Favourited 51 times We live in Hope Island which is on the northern end of the Gold Coast ( With sleek hotels and restaurants, Australia's Gold Coast is transforming from touristy to sophisticated. Find out what this beach area offers.
After an overnight flight from Taiwan via Singapore with Scoot, we finally saw a beautiful view of the Gold Ahstralia looking outside of our plane.


text:
The Aqua Filter Claris F08801 cartridge from Krups slots into your espresso machine and restores the purity of water, ensuring your coffee keeps its rich aroma and flavour intact. Extremely efficient, the Aqua Filter Claris F08801 reduces chlorine by up to 85%, lead by up to 90%, copper by up to 95% and aluminium by up to 67%.
CLARIS Replacement Water Filter - Krups


text:
|User Name
|Thread Name
|Music Hosting Websites: Alternatives to MySpace (42)
|RE: Music Hosting Websites
|23 Nov 10
Tootler - thanks for starting this thread. It's very timely, given what's happening with Myspace at the moment. My page there seems fine at the moment (though I haven't tried uploading songs recently), but I hate the mess that my Home Page has become. And the other main thing that for me has really changed the character of Myspace is the huge drop in musician activity. I used to enjoy the networking with other musicians, and it was also often very useful for getting gigs, but all that's sadly mostly gone.


text:
Sharp drop in global bond yields indicates markets expect rough sledding ahead for the global economy — President Trump's announcement last Thursday of another round of tariffs on Chinese goods triggered new concern about deteriorating global economic conditions. That concern has mainly been displayed by the sharp drop in global bond yields. Global stock markets have […]Read More
-Crude oil stocks rise modestly vs expected decline-Crude stocks rise first in 8 weeks-Gasoline stocks rise solidly vs ideas for small decline-Distillate stocks rise modestly more than expectedRead More
Overnight's break above yesterday's 130.105 high reaffirms the major bull trend and leaves yesterday's 129.15 low in its wake as the latest smaller-degree corrective low this market is now minimally required to fail below to even defer, let alone threaten the major uptrend and our long-term bullish count. Per such, this 129.15 low becomes our new short-term risk parameter […]Read More
Exactly like yesterday's weakness in diesel and RBOB discussed, crude's break yesterday afternoon and overnight below last Thur's 53.59 low reaffirms the developing downtrend and our broader peak/reversal count from 11-Jul's 60.94 high introduced. This resumed weakness leaves smaller- and larger-degree corrective highs in its wake at 56.05 and 58.82, respectively, from which a still-advised bearish policy and […]Read More
FINANCIALS, METALS AND ENERGY Sep E-mini stock futures this morning are up +7.00 points (+0.24%) and European stocks are up +1.29% on dovish central banks. New Zealand's central bank (RBNZ) cut its benchmark rate by 50 bp to a record low 1.00%, double expectations for a 25 bp cut, and the Reserve Bank of India […]Read More
Kudlow says U.S. still expects early-Sep trade talks but China may need another cooling-off period — The markets are waiting to see if China will announce any further retaliatory moves in response to President Trump's announcement last Thursday of a 10% tariff on another $300 billion of Chinese goods effective Sep 1. China may wait to […]Read More
US/Chinese trade war is quickly moving towards maximum pressure — Global investors on Monday were surprised by the extent of China's in-your-face retaliation with its move to halt all purchases of U.S. farm products and cause the yuan to fall beyond the psychological level of 7 yuan/USD to a new 11-year low. Moreover, there is likely […]Read More
For months and months since Nov 2016 and with the very rare occasion of a spasm correction, this market has just been a dog. In late-May following a bullish divergence first in daily momentum and subsequently in WEEKLY momentum amidst historically bearish sentiment, we discussed the developing prospect of a base/reversal threat that could be […]Read More