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A light earthquake magnitude 4.3 (ml/mb) strikes 4 kilometers (2 miles) from La Gomera in Guatemala on Wednesday. Exact time and date of earthquake 12/08/15 / 2015-08-12 15:44:29 / August 12, 2015 @ 3:44 pm UTC/GMT. The earthquake occurred at a depth of 87.55 km (54 miles). Exact location, longitude -91.0866° West, latitude 14.0966° North, depth = 87.55 km. A tsunami warning has not been issued (Does not indicate if a tsunami actually did or will exist). The temblor was detected at 09:44:29 / 9:44 am (local time epicenter). Unique identifier: us100031h3. Ids that are associated to the event: us100031h3.
Epicenter of the event was 86 km (54 miles) from Guatemala City (c. 994 900 pop), 79 km (49 miles) from Mixco (c. 473 100 pop), 72 km (45 miles) from Villa Nueva (c. 406 800 pop), 73 km (45 miles) from Petapa (c. 141 500 pop), 84 km (52 miles) from San Juan Sacatepéquez (c. 136 900 pop), 74 km (46 miles) from Villa Canales (c. 122 200 pop). Close country/countries, Guatemala (c. 13 550 000 pop) (That might be effected). Closest city/cities/towns to epicentrum/hypocenter was Chichicastenango, Nueva Santa Rosa, Chinautla (min 5000 pop).
In the past 24 hours, there have been one, in the last 10 days one, in the past 30 days six and in the last 365 days sixty-one earthquakes of magnitude 3.0 or greater that has struck near. Earthquakes 4.0 to 5.0 are often felt, but only causes minor damage. Every year there are an estimated 13,000 light earthquakes in the world.
Did you feel it?
How did you react? Was there any damage to buildings? Leave a comment or report about shaking, activity and damage at your home, city and country. This data comes from the USGS Earthquake Notification Service. Read more about the earthquake, Seismometer information, Distances, Parameters, Date-Time, Location and details about this quake, that has occurred near: 4 km WNW of La Gomera, Guatemala.
Copyright © 2015 earthquakenewstoday.com All rights reserved.

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Cap & Gown Units will be delivered on campus at each respective High School just prior to Graduation Commencement.
Graduation items will be delivered on campus and Announcements will be delivered to the school 6 weeks before Graduation.
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How To Obtain More Subscribers For Your YouTube Gaming Channel?
A YouTube channel without subs is a show without an audience and it can promptly become disparaging uploading videos and obtaining no subscribers. So as to get more subscribers you have reached put on your own in their area. A customer is a person who enjoys your content so much they intend to be educated each time your network is updated with brand-new content. That is a huge compliment to give a person, so it is understandable that not every person that views your video clips is most likely to jump on the client bandwagon. That being stated, there are some things you can do to enhance your turnover and also begin raising your subscribers. The more you have available in the sea of YouTube video clips, the a lot most likely someone is to encounter among them and find your channel. You will additionally intend to establish a routine for when you release your videos.
If individuals see you are including new web content on a consistently arranged basis, they are far more likely to subscribe then if they see you have not added anything in a while and also when you did it was sporadic. Nothing builds a sense of neighborhood much better than a material maker who reacts and also consults with their target market. If a conversation damages out in the comment area connecting to what was posted, chip in and offer your two cents. Even if the comments are less than friendly, thanks them for offering it a watch and request for some positive objection other than if they are trolling naturally. Attempt ending your video with a telephone call to the customers asking their thoughts on something and even an idea for your next video clip. And buy youtube subscribers cheap entailed will go a lengthy way in constructing a partnership with them that will certainly maintain them around for a long time and also spread the great word of install about you.
As soon as you have discovered a few, make up a friendly message discussing a little regarding your network and what you do. You may then intend to suggest exchanging places on each other's featured listings. Currently this is a huge option for an additional YouTube to make, and you might wish to wait until you have a respectable video collection accumulated prior to you go around asking people. If they see you are committed and draining material routinely, they will more than likely approve your invitation and your channel will gain that much exposure. One more substantial advantage of exchanging highlighted areas with somebody in your same area is that you will be presenting on your own right to your target market. If you were to develop a let's play network for Dead Area and traded featured spots with a well known YouTube knitter, opportunities are very few of their audiences would want to check your network out.


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By Conner Carey updated on 10/11/2018
With WatchOS 3 on Apple Watch, you can Scribble messages to friends from your watch instead of sending preset replies, emojis, or picking up your iPhone. The Scribble feature allows you to use your finger to scribble each individual letter of your reply. It's fairly easy to do, but probably best for shorter messages. You wouldn't want to write a novel with Scribble messages on Apple Watch, but you might use it to say, "ok," or "omw," which is short for on my way. Here's how to Scribble messages on the Apple Watch with WatchOS 3.
Related: How to Add and Listen to Music on Your Apple Watch—The Complete Guide
Master your iPhone in one minute a day:
Sign up to iPhone Life's Tip of the Day Newsletter and we'll send you a tip each day to save time and get the most out of your iPhone or iPad.
How to Scribble Messages on the Apple Watch
Open the message you want to reply to on your Apple Watch.
Scroll down. Below the message you'll see Scribble. Tap it.
Use your finger to write each letter as though your finger were a pen. The Scribble feature will automatically figure out what letter it is.
Tap Space to insert a space between words, or the back button to erase a letter.
Tap send when you're done.
I was skeptical of the Scribble feature when Apple introduced it, but it works really well. For sending short replies or updates, it's incredible convenient.


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Travel Guide: Best 4 New England Lobster Spots (Travel Photography)
I once lived in Boston with Amy while I attended grad school. That time was a really rich season of my life; I learned and grew and travelled a lot, and made great, lifelong friends (like Mary Catherine). I still miss New … Continue reading
NOLA #5: Streets of New Orleans
NOLA has many famous streets, and unique street signage. Traces of Mardi Gras are dotted around the city…look up every now and then and you'll find beads. Bourbon Street Proof that I was actually in NOLA – a photo of … Continue reading
NOLA #3: Out and About
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Posted in Travel Tagged Algier's Point, Boats, cargo, cargo ships, diverse, food photographer, getting around in New Orleans, Louisiana, Mighty Miss, Mississippi River, New Orleans, New Orleans Food Guide, New Orleans restaurants, New Orleans Travel Guide, NOLA, restaurants, river, south, southern, travel, travel photographer, travel photography, walking Leave a comment
NOLA #2: Eating and Drinking in Food Heaven
When I went to New Orleans, I had simple goals: Eat and drink See friends Consider the impact of Katrina, and Photograph all of the above. You already know that I am a foodie, and NOLA is foodie heaven. The … Continue reading
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NOLA #1: 5th Anniversary of Katrina
Five years ago today, Hurricane Katrina broke this levy and others around NOLA. Water gushed into New Orleans' Lower 9th Ward, knocking homes off their foundations, breaking trees, and ending the lives of over 1,000 NOLA residents. Everyone remembers it … Continue reading
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Melanie has Human Resources experience across a number of industry sectors including Financial Services, Retail, Entertainment and Technology.
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|Apparatus and process for the delignification of cellulose pulp
|Kido et al.
|Method and apparatus for mixing oxygen gas with medium consistency pulp in a pump discharge
|Continuous feeding system for treatment towers
|Verreyne et al.
|Valve means
|Bleaching of cellulose pulp in towers in completely filled and closed system
|Method for blowing out pulp digesters
|November, 1986
(a) a vertical, cylindrical vessel having a lower end and an upper end;
(b) a frusto-conical bottom chamber having side walls, the base of which is joined to said lower end of said vessel, and piping means for introducing a mixture of untreated cellulosic pulp and treatment chemicals axially into said bottom chamber;
(c) a distributor comprising a fixed cone located coaxially within said frusto-conical bottom chamber, wherein the vertex of said cone is oriented downward, and wherein said distributor is structured in conjunction with said bottom chamber walls to promote flow of said mixture upward through said cylindrical vessel at a constant velocity; and
(d) a head connected to said upper end wherein said head includes piping means for withdrawing treated cellulosic pulp from said reactor system;
wherein all components in said reactor are structured to be static and immobile during the introduction and distribution of the mixture, and during chemical treatment of the mixture.
This invention pertains to the treatment of cellulosic pulp and in particular to a reactor system and a method for removing lignin or color from virgin or secondary pulp by reaction with oxygen or ozone.
Oxygen delignification is a well-known process for removing lignin from wood pulp by treatment with oxygen and alkali followed by washing to remove soluble oxygen-lignin reaction products. The oxygen delignification reactions are typically carried out by mixing oxygen with medium consistency, heated alkaline pulp and passing the resulting mixture through a reactor with a sufficient contact time to allow the reaction to proceed to the desired degree. One type of reactor used for delignification is a vertical upflow reactor in which the pulp-oxygen mixture is introduced into the bottom of the reactor, flows upward while the reactions take place, and treated pulp is withdrawn from the top of the reactor.
The reactor feed mixture can be prepared by methods known in the art. U.S. Pat. No. 4,886,577 discloses the use of a specifically-designed centrifugal pump in which a pulp slurry is degassed by vacuum while passing through the pump, followed by addition of oxygen directly into the pulp at the pump discharge utilizing a shear plate or an oxygen permeable material which causes the oxygen to be introduced as small bubbles. South African Patent Application 868664 describes an alternate method to introduce oxygen into pulp which comprises passing the heated pulp in a completely fluidized state through an unobstructed flow path where it is contacted with highly dispersed oxygen bubbles ranging from 2 to 10 microns in diameter. This patent application also summarizes earlier alternative methods for oxygen dispersion described in the prior art. Australian Patent Application 22021/88 describes a similar method for introducing oxygen or oxygen-steam mixtures into the pulp.
In oxygen delignification at temperatures typically in the range of 80° to 120° C., the amount of oxygen required for delignification is much larger than the amount of oxygen soluble in the liquor associated with a given amount of pulp. In order to supply sufficient oxygen for delignification in the reactor, it is therefore necessary to incorporate bubbles of free oxygen gas in the pulp introduced to the reactor. It is desirable that these bubbles be very small in order to maximize the interfacial area so that additional oxygen can dissolve in the liquor as dissolved oxygen is consumed in the delignification reactions. The reactor system should be designed to achieve a constant upward flow velocity at all radial locations in the reactor, i.e., plug flow. Deviations from plug flow, in which some portions of the pulp move at a higher velocity and thus have less residence time in the reactor than other portions of the pulp, will cause uneven delignification and poor product quality. Careful design of the inlet and outlet sections of the reactor is necessary, since both sections influence pulp flow distribution throughout the reactor.
U.S. Pat. No. 5,034,095 discloses an upflow reactor for oxygen delignification comprising a cylindrical vessel having conical chambers connected to the inlet (bottom) and outlet (top) of the reactor wherein pulp is introduced and withdrawn at the axial center of the respective conical chambers. The convergence angle of each conical chamber, also defined as the included angle, is less than 60 degrees, preferably 20-60 degrees. No device to aid in pulp distribution or withdrawal is used in either the inlet chamber or the outlet chamber. This patent also describes a type of prior art reactor which utilizes a rotating mechanical distributor at the inlet and a mechanical discharge device at the outlet to aid in distribution and withdrawal of pulp from the reactor. These mechanical devices, which are widely used in commercial reactor systems, are effective for pulp feed distribution and withdrawal but can increase capital and maintenance costs for such reactor systems.
Improved reactor designs for oxygen delignification are desirable to achieve consistent product homogeneity and minimize the capital and operating costs of the reactor system. Such designs should emphasize operating simplicity and minimize complex design features. The reactor system of the present invention described and claimed below satisfies these requirements and offers improvements over prior art reactor systems.
The present invention is a reactor system for the chemical treatment of cellulosic pulp comprising one or more reactors, wherein each reactor includes a vertical, cylindrical vessel having a lower end and an upper end, a frusto-conical bottom chamber joined at the base to the lower end of the vessel, and piping means for introducing a mixture of untreated cellulosic pulp and treatment chemicals axially into the bottom chamber. Oxygen and ozone are preferred treatment chemicals. A distributor comprising a cone is located coaxially within the bottom chamber; the vertex of the cone is oriented downward, and the distributor operates in conjunction with the bottom chamber to promote flow of the pulp-oxygen mixture upward through the cylindrical vessel at a constant velocity. A head connected to the upper end of the cylindrical vessel includes means for withdrawing treated cellulosic pulp from the reactor system which comprises a plurality of regularly placed nozzles for injecting liquid to dilute the pulp for easy withdrawal. The feed distributor at the lower end and the withdrawal means at the upper end of the reactor operate in combination to maintain plug flow of pulp and oxygen through the reactor, thus ensuring even delignification and a homogeneous product. The feed distributor allows quiescent flow of pulp and dispersed oxygen, thus eliminating the potential for oxygen bubble coalescence caused by mechanical distribution devices.
FIG. 1 is a sectional isometric drawing of the reactor of the present invention.
FIG. 2 is a sectional drawing of the upper portion of the reactor of the present invention.
FIG. 3 is a top view of the reactor of the present invention showing a portion of the head and nozzles.
FIG. 4 is a cross-sectional view of a nozzle in the head of the reactor of the present invention.
The invention is a reactor system for the chemical treatment of cellulosic pulp as shown in the sectional isometric drawing of the reactor portion of the system shown in FIG. 1. Cylindrical vessel 1 is equipped with frusto-conical bottom chamber 3 in which inverted cone 5 is located coaxially near the small end of the bottom chamber. Vessel 1 has a length to diameter ratio L1 /D1 between about 5 and 10, preferably between about 6.5 and 8.0. Cone 5 is a solid cone attached to the inner surface of bottom chamber 3 by at least two brackets 7 and 9; preferably three or more brackets are used. Flanged opening 11 is attached to the small end of the bottom chamber and serves as the pulp inlet. Angle a1 is between about 30 and 45 degrees, so that the included angle or convergence angle of the frusto-conical bottom chamber is between about 60 and 90 degrees, preferably about 70 degrees. The included angle of cone 5 is generally equal to the included angle of bottom chamber 3, and cone 5 is preferably located near the inlet of bottom chamber 3 but may be located at any point along axis 13 within bottom chamber 3. The diameter d of the base of cone 5 and L2, the axial distance between the bases of cone 5 and bottom chamber 3, are selected such that the ratio L2 /d is between about 3 and 7, preferably between about 4.2 and 5.4. Perpendicular distance b between the walls of bottom chamber 3 and cone 5 is fixed by the values of L2 and d, and is preferably between about 200 and 300 mm depending upon diameter D1 of cylindrical vessel 1. The ratio of the vessel diameter D1 to the cone base diameter d is between about 4 and 10, preferably between about 6 and 8.
The combined bottom chamber 3 and cone 5 serve as the distributor for pulp and treating chemicals entering the reactor through flanged opening 11. When the treating chemicals include highly dispersed bubbles of reactive gases such as oxygen or ozone, it is highly desirable that these bubbles remain small; the reactor system therefore should be designed to minimize bubble coalescence, since larger bubbles have less interfacial area and can promote undesirable channelling in the reactor. The design of bottom chamber 3 and cone 5 allows the flow and distribution of pulp into the reactor with minimum disturbance, thereby minimizing bubble coalescence.
Head 15 having a generally ellipsoidal or dished shape is attached to the upper end of vessel 1 and includes a concentric flanged outlet 17 for removal of treated pulp and a plurality of nozzles 19 for injecting a suitable aqueous liquid, such as for example washer filtrate, into the pulp to reduce pulp consistency which aids pulp withdrawal and eliminates plugging. The generally ellipsoidal or dished shape of the head is selected based on typical pressure vessel design practices as known in the art. The liquid is supplied at the necessary pressure by known pumping means. Nozzles 19 project through head 15 and are installed at angles to the surface of head 15 as illustrated in FIG. 1. The inside diameter D6 of each nozzle is typically between about 30 and 70 mm, and each nozzle extends into head 15 a distance of between about 100 and 300 mm. The ratio D6 /D1 between the inside diameter of each nozzle and the diameter of vessel 1 is typically between about 0.008 and 0.020. The angled orientation of nozzles 19 serves to impart a moderate degree of beneficial circular or swirling motion to the pulp during withdrawal through outlet 17. Nozzles 19 are preferably installed in one or more circular patterns concentric with the axis of vessel 1, wherein the nozzles on a given circular pattern are equally spaced on the pattern. At least eight nozzles are generally preferred, but any reasonable number may be installed as needed. Typically 16 nozzles are installed in two circular patterns as illustrated in FIG. 1.
Nozzles 19 are oriented relative to head 15 as illustrated in FIG. 2, and section 4--4 is presented in FIG. 4. Angle a2 is between about 25 and 65 degrees, preferably about 45 degrees, as measured between tangent 25 and axis 21 of specific nozzle 23. Tangent 25 is a line drawn tangent to the circle formed by the circular pattern at the location of nozzle 23, or more specifically at the intersection 27 of axis 21 and the circle formed by the circular pattern of nozzles. Because of the curvature of head 15, a second angle must be defined to fix the exact orientation of each nozzle. FIG. 3, which is a top sectional view of head 19, illustrates angle a3 formed by axis 21 of nozzle 23 and radial line 29; this angle is less than 90 degrees and greater than 45 degrees, and depends upon the radial distance of the nozzle from the axis of vessel 1. Radial line 29 is a radial line drawn perpendicularly from the axis of vessel 1 through point 27 of FIG. 4. All nozzles are angled to discharge in the same general circumferential direction as illustrated in FIG. 1.
The diameters D2 and D3 of inlet 11 and outlet 17 respectively are selected relative to vessel diameter D1 such that the ratios D2 /D1 and D3 /D1 are between about 0.12 and 0.20. The diameters D4 and D5 of the circular patterns of nozzles 19 are typically selected such that the ratios D4 /D1 and D5 /D1 are between about 0.3 and 0.8. Bottom chamber 3 and cone 5 act in combination with the dilution nozzles in the reactor head to ensure even plug flow of the pulp upward through the reactor, which in turn ensures a highly homogeneous pulp product.
The reactor described above is useful for the treatment of any type of cellulosic pulp including virgin pulp prepared from wood chips or secondary pulp prepared from waste paper material. The pulp can be prepared by means well-known in the art, and can be subjected to prior process steps such as disintegration, screening, delignification by sulfate or other chemical processes, and other known steps. Pulp entering the reactor therefore comprises cellulosic fibers containing lignin and/or other color-causing materials, water, soluble treatment chemicals such as soluble alkaline compounds, and optionally dispersed oxygen, ozone, or other reactive gases. Certain types of secondary pulp may also contain contaminants such as binders, polymers, polymeric inks, adhesives, and the like. When oxygen is used for treating virgin pulp, the oxygen reacts with lignin to form reaction products removable in succeeding washing steps. When oxygen is used for treating pulp prepared from waste paper material, lignin and/or color bodies and/or other contaminants react with the oxygen to form suspended and/or soluble reaction products removable in subsequent washing, screening, or deinking steps. The reactor of the present invention may be used in a single stage configuration, or may be used in two or more stages for series treatment of pulp at different process conditions.
The reactor of the present invention is particularly useful in medium consistency (5 to 20%, preferably 8 to 14% consistency) oxygen delignification in which oxygen is dispersed as fine bubbles in the pulp prior to entering the reactor. In oxygen delignification, it is important that the small oxygen bubbles remain dispersed while the pulp flows upward through the reactor during which the oxygen dissolves in the liquor and reacts with the lignin or other color-causing materials to yield reaction products which are washed from the pulp in subsequent steps. Oxygen dosage is typically 0.1 to 5 wt % on oven-dried pulp. The feed distribution achieved by bottom chamber 3 and cone 5 allows quiescent flow of pulp and dispersed oxygen into the reactor, thus eliminating the potential for oxygen bubble coalescence which could be caused by mechanical distribution devices. Pulp reactor residence time for oxygen bleaching is typically between about 45 and 60 minutes. For ozone bleaching, reactor residence times range from 0.5 to 10 minutes; dosage is typically between 0.05 and 1.0 wt % on oven-dried pulp.
Removal of treated pulp is accompanied by the injection of an aqueous liquid, such as for example washer filtrate, through nozzles 19 at a suitable flow rate to dilute the pulp such that the ratio of the consistency after dilution to the consistency before dilution is between about 0.5 to 0.75. For example, a pulp with a consistency of 12% would be diluted to a consistency of between 6 and 9% prior to withdrawal from the reactor. This liquid injection also induces a moderate degree of beneficial circular or swirling motion to the pulp during withdrawal through outlet 17. The dilution of the pulp upon withdrawal serves two purposes: first, it ensures even flow distribution of the pulp through the reactor in conjunction with bottom chamber 3 and cone 5, and second, it eliminates the possibility of plugging when withdrawing pulp through the reactor head 15 and outlet 17. The liquid injected through nozzles 19 provides an excellent means for the introduction of additional treating chemicals such as surfactants, enzymes, acids, chelants, or other compounds if required in downstream process steps.
The application of the reactor system described above to medium consistency oxygen delignification is illustrated by the following Example. Steam and alkali are added to 1100 metric tons/day of medium consistency kraft pulp at the suction of a Kaymr MC Model 15 pump. Oxygen is injected into the discharged pulp by means of porous diffusers. The oxygenated pulp is reheated by steam injection to 92° C. and flows into the reactor of FIG. 1 at a pressure of 121 psig through bottom chamber 3 by which it is distributed into reaction vessel 1. At this point, the pulp has a consistency of 12.0%, a pH of 12.5, a Kappa no. of 15, and contains 15 kg of oxygen per metric ton of air dried pulp. The mixture of pulp, alkali, and oxygen flows upward through the reactor at a residence time of 50 minutes. At the top of the reactor but prior to dilution, the pulp temperature is 95° C. due to the exothermic delignification reaction and the pressure is 60 psig. Pulp filtrate is injected through 16 nozzles, each 38 mm I.D., in the reactor head as illustrated in FIG. 1 to dilute the pulp is a consistency of 7.5%, which cools the diluted pulp to 85° C., and the pulp is withdrawn through discharge pipe 17. The delignified pulp, which now has a Kappa no. of 90, is ready for washing and bleaching prior to the final papermaking step.
The reactor of the present invention differs from prior art reactors and has several unique features and advantages over such reactors. First, the present reactor utilizes no mechanical devices for pulp feed, distribution, or discharge. This reduces capital and operating costs, and also introduces no agitation which could cause the small, dispersed oxygen bubbles to coalesce. As earlier described, coalescence is undesirable because it reduces the oxygen gas interfacial area, thus reducing the oxygen dissolution rate and therefore the delignification rate. In addition, large oxygen bubbles in the reactor may induce channeling resulting in a nonhomogeneous product. The reactor also differs from the reactor described in earlier-cited U.S. Pat. No. 5,034,095 which utilizes conical top and bottom reactor sections having convergence angles between 20 and 60 degrees, in contrast to the conical bottom chamber of the present invention which has a convergence angle greater than 60 and less than 90 degrees. These conical sections in U.S. Pat. No. 5,034,095 are essentially open and contain no distribution or discharge devices.
The reactor system of the present invention, which utilizes the unique combination of a simple conical inlet distributor and dilution prior to discharge allows the controlled processing of cellulose pulp at uniform plug flow reactor conditions and eliminates the possibility of plugging during pulp discharge. The system can be used for delignification of virgin pulp or for the removal of color-causing contaminants in pulp prepared from waste paper materials, and is particularly useful in the treatment of such pulps with oxygen.
The essential characteristics of the present invention are described completely in the foregoing disclosure. One skilled in the art can understand the invention and make various modifications thereto without departing from the basic spirit thereof, and without departing from the scope and range of equivalents of the claims which follow.


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Let's finish up our fabulous Emmys red carpet coverage, dear readers.
Month:September 2013
2013 Emmy Awards, Part 2
Let's keep the Emmys train rolling, dear readers.
2013 Emmy Awards, Part 1
Welcome, dear readers, to the 2013 Emmy Awards!
2013 Pre-Emmys Parties
Gear up for tonight's big show by judging what TV's biggest stars wore to the pre-Emmy Awards parties this weekend.
Project Runway Recap: S12 E10
They say a picture is worth a thousand words. So a picture of a man-child in a facial mask ironing his jorts on the brink of a complete emotional breakdown must be worth a few million, right?
Front Row at London Fashion Week Spring 2014
Is there anything better than a hefty dose of London fashion? I think not, dear readers.
2013 Toronto Film Festival, Part 2
Let's head to Canada, eh, dear readers?
No more posts.


text: North American Whitetail Online Staff - June 05, 2012 13 Awesome Reader Photos for May 2012 We get terrific trophy photos from readers all across North America. Here are the bucks we featured in our Deer of the Day area from the past month!JEFF ROGERS - VirginiaAfter hearing the shots of his dad and brother-in-law that took deer, Jeff came down from his stand to help out. While admiring his the fallen bounty of his kin, he spotted this 150-inch buck following a fence line and punched his buck tag! NATE BODWAY - Wisconsin10-year-old Nate Bodway was participating in a mentor hunt with his father Bruce at the start of Wisconsin's nine day gun season. They spotted this great nine point not far from their home where he dropped the buck with his new .223. CLINT CATLIN - Sioux Lookout Region, Ontario, CanadaWhile hunting with his son-in-law Colin in the Sioux Lookout, Ontario region, Clint Catlin took this fantastic 11-point buck with his .243 at 150 yards. DAKOTA MORRIS - OhioThis 182-inch buck is the third buck for nine-year-old Dakota Morris! SAMANTHA INMAN - TexasMassachusetts native Samantha Inman took her first ever buck while hunting Texas hill country! BRAD STROHM - PennsylvaniaWhile hunting in a management unit in Lebanon County, PA, Brad Strohm was able to take this fantastic buck that grossed 150 3/4 inches. JESSE MARUSCHAK - MissouriThis is the second public land rifle trophy for Missouri hunter Jesse Maruschak. Last year he dropped a 193-inch giant. This year his buck green scored 140 inches! NORMAN SMITH - OklahomaHunting near Alva, Oklahoma, Norman Smith took this fantastic buck during muzzleloader season! KEN JAROSINSKI - New YorkKen Jarosinski was bowhunting outside of Bristol, New York on November 11, 2011 when he spotted a piebald buck. It was his first time ever seeing a piebald so he wasted little time in putting the buck on the ground! JEFF SCHOEPS - IllinoisUsing an Easton arrow fletched with blazer vanes in pink to support the women in his life that have battled breast cancer, Jeff Schoeps took this great buck the second week in November. NICK CARTER - KansasBattling a stiff wind, Nick Carter was able to take this mature 10-point buck from 12 yards! TONY SMITH - MichiganHunting in a deer management cooperative in Eaton County, Michigan, Tony Smith was able to drop this fantastic 144-inch buck using his Hoyt Bow! MASON ECKERMANN - KansasMason Eckermann of Caldwell,KS brought this monster down on the evening of Dec. 6, 2011 during the Kansas rifle season. The great buck green grossed 167! TYLER WELCH - WisconsinWhile hunting in Dunn County, Wisconsin, Tyler Welch was able to drop this absolute stud of a buck that weighed 240-pounds dressed! DANIEL LIMBACH - OhioDaniel took this 203 3/8-inch non-typical the first week in November. He was able to put an arrow in the massive buck from 15 yards! GET THE NEWSLETTER Join the List and Never Miss a Thing. Sign Me Up


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Recent reports proven that neovasculature of particular murine tumours inhibits migration of lymphocytes to malignant cells. was observed in specimens of medullary breast carcinoma displaying elevated expression of CD54 (ICAM-1) and CD106 (VCAM-1) as compared with ductal breast carcinoma displaying diminished expression of these CAMs (Bouma-ter Steege em et al /em , 2004). Correspondingly, the experiments on tumour-bearing mice shown upregulation of vascular CAMs manifestation following angiostatic therapy or of T-cell therapy combined with result in of inflammation, which was accompanied by intense infiltration of malignant lesions by lymphocytes and reduction of tumour size (Garbi em et al /em , 2004; Dirkx em et al /em , 2006). Despite the obvious attractiveness of mode of tumour-immune evasion, it cannot be automatically applied to all types of murine and human being malignancies because of marked variations between vascular mattresses in unique anatomic locations (Essler and Ruoslahti, 2002). The incidence of prostate carcinoma is definitely increasing continuously and no efficient curative methods are currently available. In course of this disease, the numbers of newly formed microvessels gradually TMP 269 manufacturer increase (Montironi em et al /em , 1993; Mazzucchelli em et al /em , 2000; Bono em et al /em , 2002; Strohmeyer em et al /em , 2004; Ozawa em et al /em , 2005). However, it isn't known whether these neovessels might attenuate migration of lymphocytes to malignant lesions and if therefore, whether TMP 269 manufacturer vascular CAMs are participating. We address this matter by relating microvessel thickness (MVD) and percentages of the vessels expressing main CAMs towards the level and COL4A1 patterns of leucocyte infiltrate in specimens of individual prostate adenocarcinoma. Because nodular hyperplasia from the prostate gland (NHPG) is normally a common histopathological selecting in males of the generation and hyperplastic adjustments were also discovered in perimalignant harmless regions of carcinoma specimens, tissues specimens suffering from NHPG were utilized being a control for the prostate gland not really suffering from the malignant disease. Components AND METHODS Tissues specimens Some 28 prostate adenocarcinoma specimens attained by radical prostatectomy and 30 NHPG TMP 269 manufacturer specimens attained by transurethral resection had been available in the Institute of Pathology, Soroka School INFIRMARY. Gleason score beliefs for carcinomas had been 5 in a single out of 28 situations, 6 in four out of 28 situations, 7 in 17 out of 28 situations, 8 in four out of 28 situations and 9 in two out of 28 situations. All tumours had been of Stage II T1cCT2 N0 M0. The mean age group of carcinoma sufferers was 64 years, mean age group of NHPG sufferers was 71 years. All examinations using specimens extracted from sufferers were accepted by the institutional Helsinki Committee and had been carried out based on the Israeli laws. Immunohistochemistry, estimation of MVD and evaluation of infiltrate Parts of prostate tissues had been reacted to industrial antibodies diluted, as follows: monoclonal anti-CD34 (Dako Cytomation A/S, Glosstrop, Denmark), diluted 1?:?100; monoclonal anti-CD54 (Zymed Laboratories Inc., South San Francisco, CA, USA) ready to use; monoclonal anti-CD106 (Santa Cruz Biotechnology Inc., Santa Cruz, CA, USA), diluted 1?:?25 and 1?:?50; monoclonal anti-CD106 (Dako Cytomation), diluted 1?:?25; monoclonal CD62E (Santa Cruz), diluted 1?:?25; monoclonal antiinterleukin (IL)-10 (R&D Systems Europe Ltd, Abington, UK), diluted 1?:?20; monoclonal anti-CD45 (Dako Cytomation), diluted 1?:?100; anti-CD3 (Dako Cytomation), diluted 1?:?100; anti-CD4 (Zymed) ready to use; anti-CD8 (Dako Cytomation), diluted 1?:?25; anti-CD20 (Dako Cytomation), diluted 1:100; anti-CD14 (Zymed), diluted 1?:?50; and anti-CD15 (Dako Cytomation), diluted 1?:?50. Antigen retrieval methods included boiling for 20?min in 20?mmol citrate buffer solution (pH 6) (for anti-CD34, anti-CD45, anti-CD3, anti-CD4, anti-CD8, anti-CD20, anti-CD15 anti-IL-10 antibodies), boiling for 20?min inside a TrisCEDTA buffer (10?mmol Tris foundation, 1?mmol EDTA and 0.05% Tween 20 (pH 9)) (for anti-CD106 antibodies), 0.15% trypsin in water (pH 7.8) for 20?min at 37C (for anti-CD14 antibodies). Sections of human being tonsils were used as positive settings for the aforementioned antibodies. To estimate MVD, specimens were screened at 200 magnification to detect areas enriched with blood vessels (sizzling places'). Microvessel denseness was assessed in three sizzling places' by counting blood vessels showing CD34 immune reactivity at 400 magnification simultaneously by three observers (NSV, SF and ZS), using a multiple-head light microscope and indicated like a mean of three sizzling places'. The counts were assessed inside a blind manner without the knowledge of patient's medical course or end result. Any solitary endothelial cell or cluster of endothelial cells positively stained by anti-CD34.
Tag Archives: COL4A1
The genetic modification of peripheral blood lymphocytes using retroviral vectors to,
The genetic modification of peripheral blood lymphocytes using retroviral vectors to refocus T cells against tumor cells has been recently used as a means to generate huge numbers of antigen-specific T cells for adoptive cell therapy protocols. id of a very clear improvement in antitumor impact of these Testosterone levels cells. These total outcomes obviously demonstrate modulation of gene-modified Testosterone levels cell engraftment in the NSG mouse, which supports the future testing of the combination of IL-15 and IL-7 in adoptive cell therapy protocols; nevertheless, this improved engraftment is certainly linked with the long lasting maintenance of xenoreactive Testosterone levels cells also, which limitations the best Aprepitant (MK-0869) manufacture effectiveness of the NSG mouse model in this circumstance. Launch Aprepitant (MK-0869) manufacture The adoptive transfer of antitumor lymphocytes to tumor sufferers represents a guaranteeing fresh treatment for solid malignancies such as most cancers and renal cell carcinoma (Rosenberg with IL-2 getting the predominant cytokine of choice. Prior research have got proven that the long lasting antitumor potential of Work therapies is dependent on the capability of the adoptively moved Testosterone levels cells to continue, self-renew, and differentiate into antitumor effectors and, hence, on the level of difference of such Testosterone levels cells (Berger enlargement of Testosterone levels cells is certainly that it is certainly linked with Testosterone levels cell difference in a equivalent style to that taking place upon antigen encounter, that is certainly, from unsuspecting (TN) to central storage Testosterone levels cells (TCM) and effector storage Testosterone levels cells (TEM). Furthermore, IL-2 provides been linked with Fas-mediated Testosterone levels cell apoptosis, and it also provides been noticed to hinder the growth of storage Compact disc8+ Testosterone levels cells and to promote the development of regulatory COL4A1 Testosterone levels cells (Refaeli lifestyle of Testosterone levels cells and their capability to maintain a less-differentiated phenotype. IL-2 stocks structural likeness and some of the results on Testosterone levels cells with various other people of the common gamma string (c) cytokine family members such as IL-7, IL-15, and IL-21. These and various other cytokines possess been slowly explored as substitute development elements for the era of effective growth reactive Testosterone levels cells. In particular, IL-7 Aprepitant (MK-0869) manufacture and IL-15 are known to possess a central function in homeostatic growth and success of develop lymphocytes (Schluns and Lefrancois, 2003). Prior research have got proven that these two cytokines possess the capability to improve Compact disc8+ effector Testosterone levels cell replies and are crucial elements in preserving the growth of storage Compact disc8+ and Compact disc4+ Testosterone levels cells (Berard antitumor activity of tumor-reactive Testosterone levels cells in mouse versions (Klebanoff antitumor function likened with IL-2-cultured Testosterone levels cells (Cha Hepes, 50?n2-mercaptoethanol, and 2?mL-glutamine (hereafter called Testosterone levels cell media). Era of DMF5 TCR Testosterone levels cells Peripheral bloodstream mononuclear cells had been singled out from bloodstream attained from healthful volunteers by Ficoll-hypaque thickness gradient centrifugation. Isolated peripheral bloodstream mononuclear cells had been plated at a focus of 3C5106 cells/ml of Testosterone levels cell mass media and Testosterone levels cells turned on for 48?human resources by the addition of 30?ng/ml antihuman Compact disc3 (OKT3; OrthoBiotech) and Compact disc28 (clone 37407.111; Ur&N Systems), and 100?IU/ml recombinant individual IL-2 (Chiron). For retroviral transduction, non-tissue-culture six-well china (BD Biosciences) had been covered with retronectin (10?g/ml; Takara, Invitrogen) and incubated at 4C right Aprepitant (MK-0869) manufacture away. The pursuing time, china were 2 and washed.5?ml of pathogen supernatant was added to each good. China had been centrifuged for 30?minutes in 1200 before overnight incubation in 37C/5% Company2. The pursuing day time, Capital t cells had been gathered from each well, pelleted, and re-suspended in 1?ml of Capital t cell press and added to a fresh retronectin-coated good containing 2.5?ml of fresh retroviral supernatant. After centrifugation at 1,200 Aprepitant (MK-0869) manufacture for 90?minutes, Capital t cells were still left to incubate for 4?human resources in 37C/5% Company2 and after that collected, washed, and transferred to Capital t cell press in a focus of 5105 cells/ml. IL-2 (100?IU/ml), IL-7, or IL-15 (10?ng/ml; Peprotech) had been added, and ethnicities had been modified to a focus of 5105 cells/ml every 2C3 times by the addition of refreshing Capital t cell press with cytokines. Movement cytometric evaluation of.


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image IMCD
The MakeUpIn Paris 2019, held at Carrousel du Louvre from June 18 to 19, increased its number of exhibitors to 160, among the most prestigious names in the formulation, pigment, packaging and accessories industries.
According to the Pantone Color Institute, coral is the color of the year – or more specifically Pantone 16-1546 living Coral. About it, the Executive Director of the Institute, says: "Color is this lens that equalizes the experiences of the two realities, digital and natural, which is even truer for Living Coral. Consumers who yearn for human interaction and social connectivity find the perfect human response in the pleasant, human qualities of the convivial Pantone Living Coral. "
But within the ecological wave that the world lives, the highlight of the MakeUpIn Paris 2019 was the green – even to the lips – even though the French Committee of Couleur, which explores the colors of the present since 1959, has chosen to highlight three iconic colors of makeup: Black, Red and Pink, 'colors that symbolize in their own way the beauty of yesterday, today and tomorrow.'
French Commitee of Coluleur – Black, Red and Pink
The options of experts, who in fact conduct research around the world and in various areas of society to determine the color that will be a reference for fashion, beauty, decoration, etc., reveal a study that does not necessarily have to do with the streets, that the public uses and abuses, according to their traditions, manias, preferences and even fads – or not. There are always those who bet on the neutral and okay, each in his own.
What we want to point out here is an effort by companies to cater to the color cosmetics market – and it includes makeup for mouth, eyes, skin, and nail polish. They need to be based on a study of what goes around the world to be close to their consumers. Both from the pigment and texture supplier industry to the cosmetics industry, and from the consumer cosmetics industry. So color suppliers need to pay attention to what is going around the world to define their new color charts of the year, not forgetting the seasons. And that's the big question.
Natural pigments are fashionable, of course, in the 'green' wave of natural and vegan cosmetics, plus innovative materials – metallic glows, gels … we are talking about textures, always welcome to highlight, get out of the obvious, because after all, fashion and beauty interact with luxury and sophistication – to a greater or lesser degree.
MakeUp In – always the Green topic
Highlight this year, Green was presented at the MakeUp in Paris for a new decoding by leading experts. Am I green enough? An essential issue that many brands face when creating their products and which is fully in tune with the new uses and especially with the wishes of today's consumers. The users' perception of green and its different definitions have been translated into beauty opportunities – whether in formulation or packaging."Green, Clean, Sustainable…. It has become an important question that many brands ask themselves when creating their products and which is totally in line with new uses and above all, the today's consumers expectations. We always put this topic at the heart of the MakeUp in shows conferences and we will continue to do so until it is a regular way of producing! " says the direction of the event.
Still in the eco mood, we have another color for 2020 in the vision of Color Wave, global reference of the beauty industry. The company helps product development and marketing teams stay ahead with specialized beauty color predictions, product forecasts and consumer insights. "We live in a time when ecology is more than a trend; it pervades all aspects of our lives and has become the norm. However, the echo is no longer assimilated to the insipid and the dumb. The beetroot, a sumptuous red-violet shade, incorporates the chromatic richness and energizing power of nature, vitality, health and well-being, "says Color Wave for 2020.
According to Margaux Caron, Mintel's Global Beauty Analyst trends from the last decade continue to define the new frontiers of beauty. "Today's beauty consumers are torn between two attitudes:" perfection and transformation "versus" authenticity and self-expression. " Contradictory as they may seem, these attitudes are rooted in the same cultural and social movements that occurred in the years 2010, and that will spread their influence in the coming years through four trends: total inclusion, global ethics, simplicity. high impact, texture feel.
In Brazil the makeup market has been boomed in this decade and continues to grow. According to Euromonitor International, in the period from 2013 to 2018, retail growth was 21.5%. In retail terms in 2013, it registered R $ 7,493.3 billion, increasing to R $ 9,101.5 billion in 2018. In the historic of the CAGR (Composite Annual Growth Rate) from 2013 to 2018, growth was 4.0%, forecast growth in the period from 2018 to 2023 of 7.9% and CAGR of 1.5%.
The market research provider evaluates the makeup performance, including items enamels, shadows, lipsticks and makeup kits.
Avon brings the Pro Color Enamel that dries in just 60 seconds. 3 in 1 – it's base and top coat – it has intense colors. Available in 16 colors, divided between modern, classic and neutral. Detail: The new brush has over 700 bristles for full and perfect coverage. R$ 6.99
Donx – wine, military green, navy blue
Donxs, a cruelty-free, paraben-free, high-coverage, quick-drying enamel brand, is launching an autumn-winter collection containing shades that matches the colder seasons. "We are always on the lookout for trends, from surveys and references. For this winter, in addition to worrying about the colors that are on the rise, we wanted to launch glazes that fit well with the main tones that came strong in the season, such as wine, military green, navy blue and animal print, "says Marina Espin, marketing and communications director of Donxs Cosmetics.
Vult – dark orange, nude, pearly and navy
"The Good Side of Winter" is the theme of the new Vult enamel collection for the season, featuring eight new contrasting colors of enamels based on the main trends of the fall / winter season to 2019. The formulation is 5Free: they are hypoallergenic, vegan and cruelty -free. Includes in the formulation are seaweed extracts, rich in trace elements such as calcium and magnesium, essential for healthy nails. Season colors: Cozy fireplace (creamy orange), Marathon series (creamy lead), Fondue Night (pearly nude), Underneath Duvet (creamy gray) and Stay together (creamy purple).
Risqué – metallic
Risqué, brand of the Coty Inc group, presents its new Collection Risqué Muitas de Mim, with five unpublished tones. They are hypoallergenics and count with creamy and metallic finishes. "Risqué launches this collection to expand its portfolio with colors that encourage people to use our glazes in a way that they can feel more like themselves," says Regiane Bueno, Marketing Director of Coty's consumer division.
M.A.C. neutrals
Among the international ones, neutral tones are in force. The MAC Boom, Boom, Bloom shadows palette features nine neutral shade colors for the station, which offer numerous combinations possibilities for various looks. (R $ 189.00)
Urban Decay – nudes revisitados apoiados em texturas
One of the hits from Urban Decay NAKED's portfolio of shadows has been renewed. NAKED Reloaded, bet on the reinvention of neutrals to bring an even more democratic proposal for all skin tones and all ages. There are 12 new tones, all essential nudes. The bet, however, is on the texture: from the matte velvety, metallized and with shimmer, to the shades with 3D brightness, the palette contains the exclusive pigmentation of Urban Decay, with high fixation. In addition to colors, NAKED Reloaded redefines the combination of shadows, bringing the four outer colors into full-size. Thus, you can use the most versatile options in the palette without fear that it will end. (R $ 309.00)
quem disse Berenice? – roses, brown, coral and burgundy
quem disse Berenice? (Grupo Boticário) launches new colors lipstick colours Volumão, which increases the contour of the lips. Innovative, joins makeup to skin care. The formula contains hyaluronic acid and actives that treat the skin of the lips. Its continuous use redefines the lip contour with increased production of collagen and elastin, leaving the skin of the mouth firmer. The five new colors deliver the trend tones: Rose, Brown, Coral and Burgundy adding to the 10 colors of the 2018 portfolio with shades of beige, rose, wine, red and burgundy. The new lipsticks have soft texture, SPF 15, semi-matte finish, high coverage and long lasting. In stick, easy to apply with the charm of the metallic packaging in gloss. (R $ 45.90).
Avon – brown and wine
At Avon there is a color survey, but it relates the trends of the year in general. "From what we saw on the catwalks this year, winter has a tendency to brown and wine," says the company.
Power Stay line features new lipstick with creamy texture and vibrant matte finish and 16 hours of duration without need of reapplication. (R $ 34.99)
The Powder Lipstick Mark. Epic LIP has matte finish and appearance. Powder formula with pigments that promote a matte finish. Light but Intense, vibrant, striking and strong colors. The shape is innovative and the applicator is in sponge. R $ 34.99 and the True Color Ultramatte Nude FPS 15 Lipstick, with 100% matte finish, offers great comfort and a velvety feel to the lips. (R $ 27.99)
Natura – corals, nudes and brownish
Marcos Costa, Natura's official makeup artist says: "The mouth of the moment is glossy, lacquered and with a lot of shine. The colors are pink, intense pink, light pink and nude. The shine brighten up the makeup and helps to increase the lips. It's a great choice for those who have fine lips, for example. "
The latest launch of the brand is Natura Una Lacquered Liquid Lipstick offers high coverage since the first application and intense shine. The tones are coral, nudes and brownish. (R $ 45.90).
Guerlain – rouge matte, moisturizing and antioxidant
Guerlain – For 2019 Guerlain bets on Rouge G Matte. The colors became more closed and entered tones like brown and wine. Following the trend of treatment, the long-lasting lipstick is enriched with hyaluronic acid to fill lips and black cumin seed oil, with moisturizing and antioxidant properties, to leave lips luminous.
Kiss NY – nudes, reds and roses
imPRESS by Kiss NY brings to the country superpigmented lipsticks, of long lasting, and intense colors. There are 36 creamy and shimmering tones, including nudes, reds, roses and violets. For R$ 9.99
Simply Organic – Pigments with oils and moisturizers
Simply Organic, Brazilian brand of organic, vegan, natural, cruelty-free and gender-free cosmetics has Multifunction Pigments. "Our pigments are produced with natural minerals. Versatile, they can be applied in powder, purely, or mixed in Serum, Raw Oils and Moisturizers to reach other textures. "In colors: Indigo, Magenta, Satin Rose, Sunset, Sunshine, Sweet Rose, Nude, Black and Lilac. (R $ 55)
SD Make.Up – Eyeliner Pencil in Gold and Silver shades
SD MAKE • UP, SD Group makeup brand brings the Let It Shine Eyeliner Pencil in Gold and Silver shades. They are intense colors, pearly with glitter. Vegans are waterproof; they do not transfer and offer duration over 14 hours. (R $ 48)
IMCD, exclusive distributor of BASF Colors & Effects pigments in Brazil, Uruguay, Argentina, Chile and Peru. The ECB has a wide portfolio of effect pigments for cosmetics being the focus of makeup launches. The products are natural mica base, synthetic mica base and borosilicate. The ECB has partnered with Pantone in the generation of new color trends for makeup for the next 2 years. The latest product launch was the Chione Electric Fuchsia SF90D at InCosmetics in Paris. "We will release this vegan product at InCosmetics in São Paulo through an experienced team of technicians to assist customers in color development, as well as ECB support for the Brazilian market," says the company.
Cosmotec – Pesquisa Pantone®
Cosmotec has lines with a broad range of colors to meet the main trends of the season. Its suggestions for Pantone®-chosen colors as a trend for Fall / Winter 2019-2020 (NY Fashion Week Autumn / Winter 2019/2020 Review Report) are:
Lines Intenza / Intenza Glitter: pearlescent pigments composed of synthetic mica and organic pigments. They can replace organic pigments, providing intense, vibrant and bright colors to the formulations without the need for grinding. The Intenza Glitter line has a particle size of 100-100 micrometers, giving effect of points of light. INTENZA ENVY, a dark green and Intenza Electric Pink, Intenza Tourmaline and Intenza Glitter Creativity
Sunshine Line Natural Plant Extracts: Pearlescent pigments composed of synthetic mica and natural extracts. Alternative to Iron Blue and to the Carmine (animal derivative). Sunshine Blush Bronze and Intenza Purple Reign
Sunshine Line: pearlescent pigments composed of synthetic mica. They have a low level of heavy metals and more intense colors, clear and bright when compared to the micas of natural origin.
Colormix Specialties offers numerous color choices ranging from biodegradable glitter, to natural pigments, to organic and inorganic effects, to pearly and dyes. The company offers customized solutions to create rich textures that meet and respect the diversity of Brazilian skin and the environment. Natural rheological agents, vegetal origin, mineral and biotechnology, soft and sophisticated sensory emollients such as those found in African oils, FPS boosters, which allow the creation of cosmetics and make up of the latest generation. They contain actives that promote effective anti-aging, anti-aging and anti-oxidant appeal, such as Kalinat DNA and non-invasive wrinkle fill, low molecular weight hyaluronic acid, and UV protection. make up.
According to the company, among the global color trends for the seasons in 2019 are the orange tones, which benefit the diversity of Brazilian skin tones. Gifts in the powder shades of coral tones, along with metallic tones for the night makeup. Darker shades appear in lipsticks and LIP Balms for antioxidant action for lip protection and the Nude remains for the winter season, as well as the most striking pink tones, which sometimes also appear in the gloss eyeshadows.


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Have you been to this park?
Wofford Heights Boulevard Sequoia National Forest Lake Isabella, California 93285
Boulder Gulch Campground is nestled in the foothills of the high desert at an elevation of 2,650 feet, just a short drive from Lake Isabella. The facility sits in the Giant Sequoia National Monument, offering countless recreational opportunities for visitors.
Contact Boulder Gulch Campground - Sequoia National Forest for price details.
Office Phone: 1-877-444-6777
Contact Boulder Gulch Campground - Sequoia National Forest for reservations and other inquiries.


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Weddings at The Fitzherbert Room
The smallest of the wedding ceremony rooms at Brighton Town hall is the Fitzherbert Room, situated alongside The Regency room on the ground floor. It has a capacity of 8 (if you don't value personal space).
It's ideal for small, intimate wedding ceremonies and elopements. We've had the pleasure of capturing many weddings there over the years and it always proves popular. In fact, when our little girl was just a year old, a lovely couple – Laura & John, asked us to witness their wedding alongside photographing it and as they needed us both (to witness) and as we didn't have any babysitting, they invited us to bring her along – our little girls very first wedding! Good Times!
Lucie & Rob's Fitzherbert Room Wedding
Lucie and Rob got married in the beautifully intimate Fitzherbert Room. It was just Lucie, Rob and their two friends who acted as witnesses – along with the registrars of course, which created the most wonderfully relaxed atmosphere. I love small weddings and elopements and this was a perfect example of how to do it the right way.
After the ceremony, they headed towards the delicious Salt Rooms on Brighton seafront, but en route, they spent some time laughing, throwing confetti and standing in front of pretty walls… All in the name of beautiful wedding photographs, of course!
Jen & Steves Elopement, with Marilyn and Elvis
Steve & Jen's wedding (part one! – part two can be found here!!) took place in Brighton – it was a secret ceremony with only myself and two witnesses present – witnesses who go by the name Marilyn & Elvis…
Jeni is an amazing, incredibly well-regarded makeup artist so for her to choose me to document their wedding(s!) was an insanely huge honour (no pressure!!), as she's worked with so many different photographers, across so many different genres – including high fashion shoots for the top magazines & brands. it was such a compliment that she would pick me to capture their weddings!
Anyway, We started off having a little engagement session fun around the Lanes of Brighton & ended up with a wedding at Brighton town hall, it was a roller coaster of a day. One that I am immeasurably grateful to have been a part of!
Their wedding has also been featured on RocknRollBride, so head over there for the full write up!
Laura & Johns Brighton Elopement
Heather & I had the absolute honour of not only photographing but being witnesses for the elopement of Laura & John at Christmas time. They travelled down from Northamptonshire for the day & tied the knot at Brighton Town Hall.
During the booking & enquiry process we found out that we wouldn't be able to get childcare for our daughter Robyn that day, so I told Laura that I could go & be their photographer, but that Heather wouldn't be able to act as witness – as she would have to be on mummy duty, but they said they'd be delighted to have Robyn along too!
It's not something we'd normally do – understandably not many folks would want a strangers baby at their wedding – but they're such a chilled couple, with a daughter of their own (& another en-route.), they knew the situation & welcomed our little human into their day. So not only is this Laura & Johns special day (first & foremost, of course!), but it's also Robyn's first wedding – we like to start them working early here at Faz HQ!
Hopefully, this guide has given you some inspiration for your own Fitzherbert Room Wedding, but if you need any more inspiration or tips, do let us know.
If you're looking for someone to capture your special day – we'd love to har from you.


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User Experience
Deliver the experience your users expect
In today's increasingly competitive business landscape, having a digital presence alone is not enough. Customers demand and depend on fast, consistently reliable web services. Rigor gives you the tools you need to stay ahead of the curve–and the competition.
Prioritize performance across your business. Rigor's continuous monitoring detects and alerts on performance problems before they impact users. With actionable insights, Rigor arms stakeholders with the knowledge, guidance, and tooling necessary to drive business value in a digital world.
Put simply, Rigor's easy-to-use platform helps companies deliver the best experience for their end users.
Create empathy and build insight
Gain a robust understanding of your user's experience with front-end monitoring that gives you valuable insights and the tools to respond accordingly.
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Automatically analyze your applications to ensure they align with internal standards and enforce performance budgets.
Make decisions driven by data
Integrate digital experience management earlier and throughout the software development lifecycle. From A/B testing how your site would perform with or without a third party service in pre-production to measuring the performance impact of new code releases, Rigor helps you make data-based decisions.
Test for all network environments
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Foster a culture of collaboration. Unify DevOps, lines of business, and marketing teams around digital customer experience with data that is easy-to-understand, sharable, and accessible.


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Happy New Year everyone! At the start of every new year we put together a house goals list to outline the house projects we hope to accomplish in the year ahead. If you're interested in checking out our house goals for last year click here. This year's list is a mix of big renovations and
Author: thehomebodyhouse
This post is sponsored by Houzz It's finally reveal day and I'm feeling all the emotions leading into today's post: exhaustion, relief, anxious, but mostly proud. We worked really hard the last six weeks to turn our daughter's former nursery into an official big girl room for our almost 3 year old and no one
Week Five – I'm equal parts stressed about next week's reveal but also looking forward to the madness finally ending! Haha! Up until this week, I felt pretty good with our progress – that was until we decided last minute to tack on one more really laborious carpentry project – and while I'm so happy
This post is sponsored by Houzz Week Four! Wow! How'd we get here so fast? Luckily we've made great progress and only have one big project and two smaller projects to finish up before reveal day so I'm finally feeling confident that we'll finish the room on time. Whew! If you're new or found your
We're halfway through the One Room Challenge and the pressure is really starting to build! I felt like we were flying through our projects but now that we've only got 3 weeks left, I'm getting anxious that there won't be enough time to finish! If you're new or found your way here from the One


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Mattel Bangkok Limited
Samutprakarn > Muang
jobsDB ref: JTH300003002175611
- Responsible for the entire planning system
- Develop and synchronize end to end planning from master planning to Shop floor scheduling.
- Lead a team of planners
- Bachelor or Higher of Product/Industrial Engineering /Business Administration or related filed
- at least 5 years direct experience in Master production planning
- Strong knowledge and skill of excel (Advanced excel)
- Knowledge of Maco excel
- Good analytical skills
- Good communication skill
- Good command of English
jobsDB will send your application for review directly to Mattel Bangkok Limited
About Mattel Bangkok Limited
Mattel Bangkok Limited is a subsidiary of Mattel Inc. USA which is the worldwide leader in the design, manufacturing and marketing of Children's toys. Core brands included Barbie, Fisher-Price, Disney, Winnie the Pooh, Hot Wheel, Matchbox, Cabbage Patch and more.
Something suspicious? Report this job ad


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Pideka is the medicinal division of Ikänik Farms, servicing LATAM and the EU. Pideka is authorized by the Colombian government to cultivate, produce, manufacture and distribute cannabis derivatives and seeds for medicinal, scientific and commercial sale.
The company is commited to improving the quality of life for millions around the world through the cultivation of medicinal grade cannabis and furthering R&D for genetic optimization and through applied sciences, the company hopes to better aid in the treatment of disease.


text: LOVESTRONG Marriage Marriage Ministry San Antonio http://lovestrongmarriage.com America/Chicago America/Chicago America/Chicago 20191103T020000 -0500 -0600 20201101T020000 CST 20200308T020000 -0600 -0500 CDT email@example.com 20200405T225528Z Tom & Didi Kolkebeck; 210-843-4430; email@example.com Weekend Theme: TBD Events will meet in the Holy Spirit Banquet Room: Friday, Sep 18……5:30 PM – 9:45 PM Saturday, Sep 19……7:30 AM – 8:30 PM Sunday, Sep 20……8:00 AM – 4:30 PM (Details subject to change.) The cost is $100 per couple. A $25 deposit is due with the registration form. We are limited as to the number of couples we can accommodate, and the availability is on a first-come first- serve basis. The registration cost covers dinner on Friday, three meals on Saturday, and breakfast and lunch on Sunday. It will also cover retreat materials. REGISTER HERE! 20200918T173000 20200920T163000 +29.537724;-98.505524 Banquet Hall, Holy Spirit Catholic Church @ 8134 Blanco Road, San Antonio, TX 78216, USA 0 LOVESTRONG Marriage Retreat (Sep 2020) external $100 per Couple


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How to care for your hair in four easy steps
How to care for your hair in four easy steps
The hair is not supple, easy to frizz, split ends, and it is very troublesome when combing your hair. How to care for the hair?
Especially with regard to perming and dyeing, what misunderstandings should be avoided in terms of care?
There are four steps to care for your hair. After washing your hair with cold water, you must pay attention to choosing shampoo after perming. You must choose a shampoo with repairing and nourishing effects.
In addition, the temperature of the water used for washing the hair is intolerable. It is not that the water temperature exceeds the better. Washing the hair with low temperature water is more conducive to the closure of the hair scales.
When you start washing your hair, the water temperature can be slightly higher than the body temperature, but the temperature of the water at the last pass is slightly lower than the body temperature.
Therefore, the traditional method of shampooing is not suitable after perming.
2. Strengthen nourishing hair. Female friends must pay attention to the fact that the permed hair is damaged, even dry and dull, and the moisture is nourished, so it is necessary to strengthen the nourishment.
Always use conditioner every time you wash your hair.
And once a week deep nourishing hair is also a good way to enhance hair shine.
After washing the hair, apply the essence from the root to the end of the hair. It is recommended to repeat the application three times until the essence is completely absorbed.
Consistent use for a month can make damaged hair much better, which can reduce the dryness of hair and improve gloss.
3, eat more seaweed hair gloss depends largely on the role of thyroid hormone in the body.
However, after a woman is 30 years old, her ability to produce thyroxine decreases.
And seaweed food is extremely rich in iodine, this element is the main raw material for thyroid hormone synthesis in the body.
Therefore, often eating seaweed foods has special effects on hair growth, moisturization and Wuliang.
4, to ensure the absorption of green vegetables and yellow fruits lack of vitamins also easily lead to dull hair.
For example, vitamin b has the effect of promoting hair growth and making the hair appear natural luster, while vitamin c can activate the microvascular wall, so that the hair can smoothly absorb the nutrients in the blood.
Therefore, usually eat more vitamin-rich vegetables and fruits, such as spinach, leeks, celery, mango, bananas, etc., not only can beautify the skin, but it also has less effect on restoring healthy and shiny hair.
Pay attention to hair care misunderstandings. Myth 1: Hair dyeing and dyeing are performed simultaneously rather than after dyeing. Many hair salons are not far from the hairdresser. In order to improve their performance, they will erroneously guide customers to perform dyeing and dyeing at the same time.
Because even the best hot dyeing products contain more or less chemical ingredients, which will hurt the hair. If you dye it again, it will hurt the hair. It is serious and serious and will affect the elastic color of the hair. The gloss of the hair should be treated after perming.Do it again in about a week and do deep repair after dyeing.
Misunderstanding 2: The temperature of the hair dryer is too high, and the heat resistance of the hair is not absorbed by the heat-resistant oil. The temperature of the hair is about 80'C. If the temperature is too high, the internal nutrients in the hair will be blown away.Will be dry and hairy.
Misunderstanding 3: Combing your hair vigorously Some people think that scratching your head to remove dandruff is wrong.
Because if you apply too much force, the bacteria on your nails will hurt the keratin on your scalp, and the cells will shift, which will cause scalp injuries.
Misunderstanding 4: After washing the hair, take a towel and rub it vigorously, because the hair has hair scales like fish scales.
If you rub hard, the nutritional content of the hair scales will also be lost, resulting in dry hair.
The correct way is to let the hair absorb and rehydrate.
Misunderstanding 5: For the purpose of not choosing targeted cleaning products, a family uses a cleaning product that has dandruff but uses an anti-dropping cleaning product.
This approach is certainly not scientific.
Should be targeted to choose hair loss prevention and care products, dandruff and anti-dandruff wash products, dry and split naturally use moisturizing repair products.
Myth # 6: Applying too many styling products is now popular for natural beauty. A good hairstyle is of course natural and elegant, and elegant.
Applying too much styling products to make the hairstyle too stiff, too rigid and boring, and the styling products contain alcohol.
Naturally it also causes certain damage to hair.


text: Life in the military can be rough so every now and then a recruit needs to unwind in the barracks. In this case, unwinding is a big-booty orgy that would make Uncle Sam proud. The scene starts with Sweet Sinsacion asking Raven if she works out. If she doesn't, she's going to get a real workout right now. You gotta warm up before every workout, so Sweet Sinsacion gets the blood flowing by massaging Raven's ass and then turns around for some booty-cheek poppin'. Xena can't be left out of all the fun, though. While the other two were playing, she was makin' sure she had a couple of dudes to fill her hungry pussy. "Y'all are in here ass-fuckin'," she said. "I found me a lil' sausage to go with my bun." A couple of hung studs who are ready to be served up three helpings of phat booty walk into their barracks. These three big-booty bitches must have been in dick withdrawal, because they fuck like they haven't had a good piece of meat in a minute. "Oh yeah, fuck me soldier boy," Raven says as one stud beasts on her pussy doggie-style. If there's one thing a soldier knows how to do, it's follow orders. Good thing, because these chicks can't get enough. They're poppin' pussy and sweatin' like they can't get enough sexin'. "Fuck me like you want a promotion," Sweet Sinsacion screams. They do want promotions, and show their eagerness by dropping huge nuts on Sweet Sinsacion and Xena's asses and onto Raven's face. That's what we call an honorable discharge.See More of Xena at BOOTYLICIOUSMAG.COM!


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USA/CommonState/Other states and territories
From Wazeopedia
< USA | CommonState
Revision as of 22:30, 4 July 2014 by Kentsmith9 (talk | contribs) (Created template)
|This page serves as a common template to over 50 other pages. Do not make modifications to this page before reviewing the proposed changes in this Waze forum thread first.
The other states and territories of the USA can be found in the navigation box below. Press the "show" button to open the box.


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SUPER PRETTY SUPER CUTE 超キレい超かわいい Vol ~ Japanese ADULT Magazine with DVD MARCH Issue [JAPANESE EDITION] MAR 3.
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LateRooms.com - Experience the Firenze Gelato Festival in Italy
May 03, 2010 (PRLEAP.COM) Travel NewsLateRooms.com divulges ice cream fans are advised to head to Florence next month for the city's annual celebration of the dessert.
The Firenze Gelato Festival runs from Friday May 28th to Monday May 31st, with many of the Tuscan capital's famous squares hosting ice cream workshops, tasting sessions, children's activities and exhibits.
People staying in Florence hotels should find plenty of opportunities to indulge their sweet tooth, as the whole city celebrates its reputation for high-quality ice cream during the four-day festival.
Many events are free to attend, while visitors can acquire a festival card from the information point in the Piazza Santissima Annunziata to receive discounts on tastings, parking and public transport.
According to the organisers, about 300,000 people are expected to attend this year's Firenze Gelato Festival.
The Piazza Santissima Annunziata will host an exhibition dedicated to the history of frozen desserts and the prominent role played by gelato in Florentine culture.
Although most non-Italians are familiar with the country's famous culinary exports, such as pizza and pasta, many people may not realise the popularity of gelato among native people.
The dessert differs slightly from ice cream produced in other countries, as its butterfat and sugar content is usually lower.
If you're heading to the Firenze Gelato Festival this year, we strongly advise that you book your hotel Firenze as soon as possible, given the huge popularity of the event.
Editors Notes:
LateRooms.com is part of B2C sector of TUI Travel PLC's Accommodation and Destination Division. Also within this sector are AsiaRooms.com and Hotels-London.co.uk.
LateRooms.com is the UK's leading online accommodation site offering late availability deals in over 37,000 properties worldwide, ranging from bed and breakfasts to five star luxury hotels.
LateRooms.com offers customers a saving of up to 70 per cent off the normal room rate for a variety of independent and branded hotels. Customers can book online or by phone 24/7, whether booking 12 months or 12 minutes in advance whatever time, whatever day. No other accommodation site offers this flexibility.
LateRooms.com arms customers with information to help them choose the right hotel. Users can read from over 540,000 true hotel reviews, written by customers who have booked through LateRooms.com and actually stayed at the hotel.
LateRooms.com is the first online site to use VisitBritain's official national classification system to rate its hotels, bed and breakfasts and guest houses. This ensures customers know the standards of quality they can expect when making a reservation.
To view LateRooms.com press pages, please see http://press.laterooms.com/
Contact Information
Felix Lueneberger
+ 44 (0)161 607 3460
Contact Us
Felix Lueneberger
+ 44 (0)161 607 3460
Contact Us


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Choosing a low cost loan. The best low cost loan is one that has a low, fixed APR, no arrangement fee and no early repayment fee. You might think that this perfect loan is hard to find, but there are plenty out there if you know where to look.
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Mortgages originated by banks, lenders and brokers across the country and sold on the primary mortgage market to Fannie Mae and Freddie Mac make up conventional loans. These loans offer the best terms.
The 5 mortgage types we've discussed all have a low, or no down payment. VA loans – No down payment; USDA loans – No down payment; FHA loans – 3.5% down; 203k FHA loans – 3.5% down; HomePath loans – 5% down; Conventional 97 loan – 3% down; credit scores needed for low income home loans
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Our Ultrasonic Sieve cleaner sends high frequency waves through water, effectively washing particles off of test sieves up to 200 mm in diameter. It is conveniently compact.
Inside dimension (300 mm wide, 250 mm across, 155 mm high).
Outside dimension (350 mm wide, 350 mm across, 275 mm high).
Also available is the AU-10C Ultrasonic Washer for use with sieves up to 75 mm. Contact us for details. Sieve Diameter : 200mm(8")