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The Plan
I have a busy day ahead again today. I therefore have to plan my day wisely, otherwise I can't get nothing done. Today is a sunny day. But summer will soon be gone. What a shame. That's why I try to capture summer in scented candles, with all the lovely scents of summer that make you feel like summer never ends. Well, for now, I have only French lavender scent so far. But more and more aromas will be added, as soon as I have finished making them and add them to my online store BUPPHA.uk.
It's a long process. I also have to design new labels for each perfume, packaging, containers, and so forth. Christmas will also soon arrive. So I want everything ready by then as well. It's September now. So I have plenty of time to prepare. It gives me a peace of mind when I plan everything well ahead. I have learned from my experience that things will go terribly wrong, in most cases, when you are unprepared – no matter what you do. That's why I try to prevent it from happening again at all costs. So from now on, I will outline everything in advance in order to avoid mistakes as much as I can. It also gives me more confidence and can then easily envision things that could go wrong, and thereby do whatever I can to stay away from them.
So today, I will start my day with the revision of my drama screenplay first, just a little bit. I try to break down the editing process of my manuscript into small chunks, to make it more achievable and realistic. I can just tell you that my drama script has a very unique story, plot, and characters. Furthermore, it's also based on a true story which makes it original. I therefore do not post my drama screenplay anywhere, yet. I want to keep it under wraps for now until after the rewrite is complete and, perhaps, the film has been made.
Then, the rest of the day, I will spend it to focus on my candle business. There's a lot to do as well since I just started it. So to stop myself from pulling my hair out trying to cope with all the things I need to accomplish, I have to do everything bit by bit. One small task at a time. When I have completed this one, then I can move on to the next. It's more manageable this way. Now, I will get going with all my to-dos if I want anything to get done today.


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Author(s): Graham Bishop
Date published: Jun 2018
The Temporary Eurobill Fund offers a modest, technical but concrete step that can be expanded progressively into a financial, economic and political structure if circumstances develop propitiously. This author has developed the TEF plan over several years – now comprehensively updated.
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Freedom Landing at Crosswater is a new Nocatee neighborhood that boasts a stunning location. This Nocatee community features 106 homesites, many backing up to preserve or lake. David Weekley Homes 50′ wide and 60′ wide, Dostie Homes, ICI Homes, Providence Homes and Riverside Homes each will offer unique and innovative floor plans, incorporating the Americana and nostalgic "Old Towne" theme. Homes will range in size from 1,900 square feet to more than 3,200 square feet. Lots are 50″ and 60 Wide. HOA $360/year. CDD $2151-2329/year.
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If you wish to be represented by a Realtor you will need to contact your Realtor BEFORE visiting any new neighborhoods or sales models. Many builders nowadays will not let you have Realtor representation if you visit them and register without your Realtor. If you have already visited and spoken with a Builder's Salesperson….you will need to contact the Builder's Salesperson ASAP and let them know you want to have Realtor Representation.
For Buyers Only Realty is not affiliated with any Builder or Developer. We Are Exclusive Buyer's Agents and we do not work for Sellers or Builders in order to provide 100% unbiased representation and full fiduciary to our Buyer-Clients with absolutely zero conflict of interest. There is absolutely no fee for our services as we are paid out of the Builder's marketing account. FYI – It is illegal for Builders to discount homes for Buyer's that do not have a Realtor. So be sure that you do not give up your right for your own protection by having an Exclusive Buyer's Agent to assist you in your house negotiations, helping you navigate all the complexities of understanding and choosing the right structural options and determining the right ratio of how much to spend on design center options, working on your behalf on all interactions with the builder on the various meetings and stages of home construction (pre-construction meetings, form boards install, plumbing rough-in, slab pour, framing, roofing, and electrical, pre-drywall meetings, etc, etc, all the way to Dwight's famous Blue Tape walks (the first walk) and on to completion and final walk and closing day.
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What happens when you get " Ebola Virus" – New Documentary HD 2015Read more
Ebola : Inside the Deadly Outbreak. ABC News' Dr. Richard Besser travels into the hot zone – where thousands of Africans are dying of Ebola, and doctors risk their own lives to save them. Interviews with those on the front lines, and an American survivor, weave together an incredible storyRead more
22 Oct
VICE reporter Danny Gold takes us into Monrovia, the capital of Liberia, to document the conditions that citizens there are being forced to combat in the wake of the virus' invasion. Redemption Hospital, the epicenter of Ebola treatment in the city, is where we are first introduced to the disparate state of healthcare workers' efforts […]Read more


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We introduce this communication with a brief outline of the historical landmarks in genetic modeling, especially concerning epistasis. Then, we present methods for the use of genetic modeling in QTL analyses. In particular, we summarize the essential expressions of the natural and orthogonal interactions (NOIA) model of genetic effects. Our motivation for reviewing that theory here is twofold. First, this review presents a digest of the expressions for the application of the NOIA model, which are often mixed with intermediate and additional formulae in the original articles. Second, we make the required theory handy for the reader to relate the genetic concepts to the particular mathematical expressions underlying them. We illustrate those relations by providing graphical interpretations and a diagram summarizing the key features for applying genetic modeling with epistasis in comprehensive QTL analyses. Finally, we briefly review some examples of the application of NOIA to real data and the way it improves the interpretability of the results.
Background: Linkage mapping is used to identify genomic regions affecting the expression of complex traits. However, when experimental crosses such as F2 populations or backcrosses are used to map regions containing a Quantitative Trait Locus (QTL), the size of the regions identified remains quite large, i.e. 10 or more Mb. Thus, other experimental strategies are needed to refine the QTL locations. Advanced Intercross Lines (AIL) are produced by repeated intercrossing of F2 animals and successive generations, which decrease linkage disequilibrium in a controlled manner. Although this approach is seen as promising, both to replicate QTL analyses and fine-map QTL, only a few AIL datasets, all originating from inbred founders, have been reported in the literature.
Methods: We have produced a nine-generation AIL pedigree (n = 1529) from two outbred chicken lines divergently selected for body weight at eight weeks of age. All animals were weighed at eight weeks of age and genotyped for SNP located in nine genomic regions where significant or suggestive QTL had previously been detected in the F2 population. In parallel, we have developed a novel strategy to analyse the data that uses both genotype and pedigree information of all AIL individuals to replicate the detection of and fine-map QTL affecting juvenile body weight.
Results: Five of the nine QTL detected with the original F2 population were confirmed and fine-mapped with the AIL, while for the remaining four, only suggestive evidence of their existence was obtained. All original QTL were confirmed as a single locus, except for one, which split into two linked QTL.
Conclusions: Our results indicate that many of the QTL, which are genome-wide significant or suggestive in the analyses of large intercross populations, are true effects that can be replicated and fine-mapped using AIL. Key factors for success are the use of large populations and powerful statistical tools. Moreover, we believe that the statistical methods we have developed to efficiently study outbred AIL populations will increase the number of organisms for which in-depth complex traits can be analyzed.
A new concept for multiplex detection and quantification of microbes is here demonstrated on a range of infectious fungal species. Padlock probe methodology in conjunction with qPCR and Luminex™ technology was used for simultaneous detection of ten fungal species in one single experiment. By combining the multiplexing properties of padlock probes and Luminex™ detection with the well established quantitative characteristics of qPCR, quantitative microbe detection was done in 10-plex mode. A padlock probe is an oligonucleotide that via a ligation reaction forms circular DNA when hybridizing to specific target DNA. The region of the padlock probe that does not participate in target DNA hybridization contains generic primer sequences for amplification and a tag sequence for Luminex™ detection. This was the fundament for well performing multiplexing. Circularized padlock probes were initially amplified by rolling circle amplification (RCA), followed by a SybrGreen™ real time PCR which allowed an additive quantitative assessment of target DNA in the sample. Detection and quantification of amplified padlock probes were then done on color coded Luminex™ microspheres carrying anti-tag sequences. A novel technique, using labeled oligonucleotides to prevent reannealing of amplimers by covering the flanks of the address sequence, improved the signal to noise ratio in the detection step considerably. The method correctly detected fungi in a variety of clinical samples and offered quantitative information on fungal nucleic acid.
Background: The insecticides dichlorvos, paradichlorobenzene and naphthalene have been commonly used to eradicate pest insects from natural history collections. However, it is not known how these chemicals affect the DNA of the specimens in the collections. We thus tested the effect of dichlorvos, paradichlorobenzene and naphthalene on DNA of insects (Musca domestica) by extracting and amplifying DNA from specimens exposed to insecticides in two different concentrations over increasing time intervals. Results: The results clearly show that dichlorvos impedes both extraction and amplification of mitochondrial and nuclear DNA after relatively short time, whereas paradichlorobenzene and naphthalene do not. Conclusion: Collections treated with paradichlorobenzene and naphthalene, are better preserved concerning DNA, than those treated with dichlorvos. Non toxic pest control methods should, however, be preferred due to physical damage of specimens and putative health risks by chemicals.
The aim of this study was to investigate the reliability of a new infrared light based method (IR40) for recording temporal stride patterns during treadmill running. The IR40 device, emitting a tight web of 40 infrared light beams 10 mm above the treadmill running surface, was compared to a previously validated electro-pneumatic contact shoe (CS) method while nine well-trained athletes ran at 2.8, 3.3, 3.9, 4.4, 5.0, and 5.6 m s−1. Disconnection and reconnection of the IR beams marked the stance phase. The sampling rate was 500 Hz for both methods. The stance phase duration was on average 11.5 (±8.4) ms longer with the IR40 than with the CS depending on earlier touch down (8.3 ± 6.2 ms) and delayed toe off (3.2 ± 5.3 ms) registrations. Significantly different stance phases were recorded between all velocities and for both methods. Thus, despite the fact that the IR40 systematically measured a somewhat longer stance phase duration than CS, the IR40 is nonetheless useful for temporal stride analysis during treadmill running.
Three different LED lamps with continuous spectra were compared against commonly used fluorescent lights. The lamps were characterized by light output, energy consumption and spectral quality for plant growth. The biological effects of light quality were compared by pre-cultivating seedlings of Picea abies (L.) Karst. and Pinus sylvestris L. under each spectrum for 35 days in a growth chamber with controlled temperature, humidity and photoperiod. The seedlings were then transplanted and cultivated for one vegetation period at the nursery, then planted outdoors on a forest field trial and followed for three years. The seedlings showed similar growth performance for all spectra tested. LED lamps have several advantages to fluorescent light such as energy consumption, longer life span and adjustable light intensity. Regarding light intensity the effects on growth performance were studied for both species using the most promising LED spectra. The photosynthetically active radiation (PAR) was maintained at 50, 100, 200 and 400 mu mol m(-2) s(-1). Unlike energy consumption, seedling development did not display a linear relationship to light intensity. Instead, the results show an optimum light level between 100 and 200 mu mol m(-2) s(-1) for the shade tolerant Picea abies seedlings and a level of around 200 mu mol m(-2) s(-1) for the more shade intolerant Pinus sylvestris seedlings.
Understanding the genetic basis of traits involved in adaptation is a major challenge in evolutionary biology but remains poorly understood. Here, we use genome-wide association mapping using a custom 50 k single nucleotide polymorphism (SNP) array in a natural population of collared flycatchers to examine the genetic basis of clutch size, an important life-history trait in many animal species. We found evidence for an association on chromosome 18 where one SNP significant at the genome-wide level explained 3.9% of the phenotypic variance. We also detected two suggestive quantitative trait loci (QTLs) on chromosomes 9 and 26. Fitness differences among genotypes were generally weak and not significant, although there was some indication of a sex-by-genotype interaction for lifetime reproductive success at the suggestive QTL on chromosome 26. This implies that sexual antagonism may play a role in maintaining genetic variation at this QTL. Our findings provide candidate regions for a classic avian life-history trait that will be useful for future studies examining the molecular and cellular function of, as well as evolutionary mechanisms operating at, these loci.
Sverker Johansson has written an unusual book on language origins, with its emphasis on empirical evidence rather than theory-building. This is a book for the student or researcher who prefers solid data and well-supported conclusions, over speculative scenarios. Much that has been written on the origins of language is characterized by hypothesizing largely unconstrained by evidence. But empirical data do exist, and the purpose of this book is to integrate and review the available evidence from all relevant disciplines, not only linguistics but also, e.g., neurology, primatology, paleoanthropology, and evolutionary biology. The evidence is then used to constrain the multitude of scenarios for language origins, demonstrating that many popular hypotheses are untenable. Among the issues covered: (1) Human evolutionary history, (2) Anatomical prerequisites for language, (3) Animal communication and ape "language", (4) Mind and language, (5) The role of gesture, (6) Innateness, (7) Selective advantage of language, (8) Proto-language.
Natural selection mediated by pollinators has influenced the evolution of floral diversity of the flowering plants (angiosperms). The scope of this thesis was to study: 1) phenotypic selection, 2) mating systems, and 3) floral shifts involved in plant speciation. Model plant species were Platanthera bifolia and P. chlorantha (Orchidaceae). These orchids are moth-pollinated, strictly co-sexual (bisexual flowers), and produce a spike that displays 10-20 white flowers.
I explored the influence of characters on plant fitness by using multiple linear regressions. Pollen removal (male fitness) and fruit set (female fitness) increased with more flowers per plant in three P. bifolia populations. There was selection towards longer spurs in a dry year when average spur length was shorter than in normal-wet years. Female function was sensitive to drought, which enabled an application of the male function hypothesis of floral evolution (Bateman's principle). The results show that selection may vary between populations, years, and sex-functions.
I examined inbreeding by estimating levels of geitonogamy (self-pollination between flowers of an individual) with an emasculation method in two P. bifolia populations. Geitonogamy did not vary with inflorescence size. Levels of geitonogamy was 20-40% in the smaller, but non-significant in the larger population. This may relate to lower number of possible mates and pollinator activity in the smaller population.
Platanthera bifolia exhibits the ancestral character state of tongue-attachment of pollinia on the pollinator. Its close relative P. chlorantha attaches its pollinia onto the pollinator's eyes. To explore the mechanism of a floral shift, pollination efficiency and speed was compared between the two species. The results showed no differences in pollination efficiency, but P. chlorantha had faster pollen export and import. Efficiency of pollination in terms of speed may cause floral shifts, and thus speciation.
When individuals interact, their phenotypes may be affected not only by their own genes but also by genes in their social partners. This phenomenon is known as Indirect Genetic Effects (IGEs). In aquaculture species and some plants, however, competition not only affects trait levels of individuals, but also inflates variability of trait values among individuals. In the field of quantitative genetics, the variability of trait values has been studied as a quantitative trait in itself, and is often referred to as inherited variability. Such studies, however, consider only the genetic effect of the focal individual on trait variability and do not make a connection to competition. Although the observed phenotypic relationship between competition and variability suggests an underlying genetic relationship, the current quantitative genetic models of IGE and inherited variability do not allow for such a relationship. The lack of quantitative genetic models that connect IGEs to inherited variability limits our understanding of the potential of variability to respond to selection, both in nature and agriculture. Models of trait levels, for example, show that IGEs may considerably change heritable variation in trait values. Currently, we lack the tools to investigate whether this result extends to variability of trait values. Here we present a model that integrates IGEs and inherited variability. In this model, the target phenotype, say growth rate, is a function of the genetic and environmental effects of the focal individual and of the difference in trait value between the social partner and the focal individual, multiplied by a regression coefficient. The regression coefficient is a genetic trait, which is a measure of cooperation; a negative value indicates competition, a positive value cooperation, and an increasing value due to selection indicates the evolution of cooperation. In contrast to the existing quantitative genetic models, our model allows for co-evolution of IGEs and variability, as the regression coefficient can respond to selection. Our simulations show that the model results in increased variability of body weight with increasing competition. When competition decreases, i.e., cooperation evolves, variability becomes significantly smaller. Hence, our model facilitates quantitative genetic studies on the relationship between IGEs and inherited variability. Moreover, our findings suggest that we may have been overlooking an entire level of genetic variation in variability, the one due to IGEs.
Background: Genetic variation for environmental sensitivity indicates that animals are genetically different in their response to environmental factors. Environmental factors are either identifiable (e.g. temperature) and called macro-environmental or unknown and called micro-environmental. The objectives of this study were to develop a statistical method to estimate genetic parameters for macro- and micro-environmental sensitivities simultaneously, to investigate bias and precision of resulting estimates of genetic parameters and to develop and evaluate use of Akaike's information criterion using h-likelihood to select the best fitting model.
Methods: We assumed that genetic variation in macro- and micro-environmental sensitivities is expressed as genetic variance in the slope of a linear reaction norm and environmental variance, respectively. A reaction norm model to estimate genetic variance for macro-environmental sensitivity was combined with a structural model for residual variance to estimate genetic variance for micro-environmental sensitivity using a double hierarchical generalized linear model in ASReml. Akaike's information criterion was constructed as model selection criterion using approximated h-likelihood. Populations of sires with large half-sib offspring groups were simulated to investigate bias and precision of estimated genetic parameters.
Results: Designs with 100 sires, each with at least 100 offspring, are required to have standard deviations of estimated variances lower than 50% of the true value. When the number of offspring increased, standard deviations of estimates across replicates decreased substantially, especially for genetic variances of macro- and micro-environmental sensitivities. Standard deviations of estimated genetic correlations across replicates were quite large (between 0.1 and 0.4), especially when sires had few offspring. Practically, no bias was observed for estimates of any of the parameters. Using Akaike's information criterion the true genetic model was selected as the best statistical model in at least 90% of 100 replicates when the number of offspring per sire was 100. Application of the model to lactation milk yield in dairy cattle showed that genetic variance for micro- and macro-environmental sensitivities existed.
Conclusion: The algorithm and model selection criterion presented here can contribute to better understand genetic control of macro- and micro-environmental sensitivities. Designs or datasets should have at least 100 sires each with 100 offspring.
Individuals involved in a social interaction exhibit different behavioral traits that, in combination, form the individual's behavioral responses. Selectively bred strains of silver foxes (Vulpes vulpes) demonstrate markedly different behaviors in their response to humans. To identify the genetic basis of these behavioral differences we constructed a large F2 population including 537 individuals by cross-breeding tame and aggressive fox strains. 98 fox behavioral traits were recorded during social interaction with a human experimenter in a standard four-step test. Patterns of fox behaviors during the test were evaluated using principal component (PC) analysis. Genetic mapping identified eight unique significant and suggestive QTL. Mapping results for the PC phenotypes from different test steps showed little overlap suggesting that different QTL are involved in regulation of behaviors exhibited in different behavioral contexts. Many individual behavioral traits mapped to the same genomic regions as PC phenotypes. This provides additional information about specific behaviors regulated by these loci. Further, three pairs of epistatic loci were also identified for PC phenotypes suggesting more complex genetic architecture of the behavioral differences between the two strains than what has previously been observed.
This study incorporated variations in speed and the horizontal resistance acting upon elite female skiers during double poling (DP) on a treadmill and specifically analyzed biomechanical adaptations to these variations. Whole body kinematics and pole force data were recorded and used to calculate the moment of force acting on the shoulder and elbow joints. Data were obtained with a 3D optoelectronic system using reflective markers at given anatomical landmarks. Forces along the long axis of the right pole were measured with a piezoelectric force transducer. Surface electrodes were used to record EMG activity in the rectus femoris, rectus abdominis, latissimus dorsi and triceps brachii muscles. In a first set of recordings, the participants double poled with zero elevation at five different speeds from 8 to 17 km h−1. In a second set of recordings, horizontal resistance was added by weights (0.4–1.9 kg) attached to a pulley system pulling the skier posteriorly during DP at 14 km h−1. Results showed increasing relative duration of the thrust phase with increasing resistance, but not with speed. Significant kinematic differences occurred with increase in both speed and resistance. The mean (±SD) horizontal force components ranged between 1.7 (±1.3) and 2.8 (±1.1) percent (%) bodyweight (BW) in the speed adaptation and 3.1 (±0.6) and 4.0 (±1.3) % BW in the adaptation to horizontal resistance. Peak muscle activity showed a central to peripheral (proximo-distal) activation sequence. The temporal cycle phase pattern in the adaptation to speed and horizontal resistance differed.
The national railway administrations in Scandinavia, Germany, and Austria mainly resort to manual inspections to control vegetation growth along railway embankments. Manually inspecting railways is slow and time consuming. A more worrying aspect concerns the fact that human observers are often unable to estimate the true cover of vegetation on railway embankments. Further human observers often tend to disagree with each other when more than one observer is engaged for inspection. Lack of proper techniques to identify the true cover of vegetation even result in the excess usage of herbicides; seriously harming the environment and threating the ecology. Hence work in this study has investigated aspects relevant to human variationand agreement to be able to report better inspection routines. This was studied by mainly carrying out two separate yet relevant investigations.First, thirteen observers were separately asked to estimate the vegetation cover in nine imagesacquired (in nadir view) over the railway tracks. All such estimates were compared relatively and an analysis of variance resulted in a significant difference on the observers' cover estimates (p<0.05). Bearing in difference between the observers, a second follow-up field-study on the railway tracks was initiated and properly investigated. Two railway segments (strata) representingdifferent levels of vegetationwere carefully selected. Five sample plots (each covering an area of one-by-one meter) were randomizedfrom each stratumalong the rails from the aforementioned segments and ten images were acquired in nadir view. Further three observers (with knowledge in the railway maintenance domain) were separately asked to estimate the plant cover by visually examining theplots. Again an analysis of variance resulted in a significant difference on the observers' cover estimates (p<0.05) confirming the result from the first investigation.The differences in observations are compared against a computer vision algorithm which detects the "true" cover of vegetation in a given image. The true cover is defined as the amount of greenish pixels in each image as detected by the computer vision algorithm. Results achieved through comparison strongly indicate that inconsistency is prevalent among the estimates reported by the observers. Hence, an automated approach reporting the use of computer vision is suggested, thus transferring the manual inspections into objective monitored inspections
Abstract: Terpenoids are involved in various defensive functions in plants, especially conifers. Epigenetic mechanisms, for example DNA methylation, can influence plant defence systems. The purpose of the present study was to investigate the influence of UV-B exposure on the release of terpenoids from spruce seedlings and on needle DNA methylation. Ten-week-old seedlings grown indoors were exposed to UV-B radiation during 4 h, and the volatile compounds emitted from the seedlings were analysed. Analysis of the volatiles 1, 3, and 22 d after this UV-B exposure showed that bornyl acetate, borneol, myrcene, and limonene contents increased during the first 3 days, while at day 22 the level of emission had returned to the control level. UV-B exposure decreased the level of DNA methylation in needles of young seedlings, reflected in methylation changes in CCGG sequences. Exposure of young seedlings to UV-B radiation might be a way to potentiate the general defensive capacity, improving their ability to survive in outdoor conditions. UV-B-induced defence is discussed in the light of epigenetic mechanisms.
På 11 lokaler där björk och gran vuxit i bestånd intill varandra på likartad mark uppskattades ståndortsindex (SI) för gran och björk med hjälp av brösthöjdsålder och höjd på övrehöjdsträd. På 22 lokaler (11 verkliga, 11 simulerade) uppskattades SI för gran och björk med hjälp av ståndortsegenskaper. Sambandet mellan SI för gran och för vårtbjörk sammanfattas i en tabell där SI G24 motsvarar B23 och SI G36 motsvarar B26. Marker där vårtbjörken kan konkurrera med granen i produktion bör vara friska lågörttyper med markvattenklass S eller K. Hög höjd över havet och nordliga breddgrader har också mer negativ påverkan på björkens än på granens tillväxt. På breddgrad 60-61 ºN upp till 100 m över havet uppskattas då SI för björk till B24-26 och för gran till G25-27.
På de lägre boniteterna (B23/G24) beräknas volymsproduktionen vara likvärdig för vårtbjörk och gran, medan på de högre boniteterna (B26/G36) beräknas granens medelvolyms-produktion vara upp mot dubbelt så hög som för vårtbjörk. Vårtbjörkens torrsubstansproduktion beräknas däremot överstiga den för gran på de lägre boniteterna och uppgå till ca 80% av granens torrsubstansproduktion på de högre boniteterna.
Materialet i studien är begränsat och försiktighet bör iakttagas vid generaliseringar.
This study evaluated the Moxus metabolic system with the Douglas bag method (DBM) as criterion. Reliability and validity were investigated in a wide range of ventilation and oxygen uptake and two sensors for determining ventilation were included. Thirteen well-trained athletes participated in one pre-test and four tests for data collection, exercising on a cycle ergometer at five submaximal powers (50-263 W) and at [Formula: see text]. Gas exchange variables were measured simultaneously using a serial setup with data collected on different days in an order randomized between Moxus with pneumotachometer (MP) and turbine flowmeter (MT) sensors for ventilation. Reliability with both sensors was comparable to the DBM. Average CV (%) of all exercise intensities were with MP: 3.0 ± 1.3 for VO(2), 3.8 ± 1.5 for VCO(2), 3.1 ± 1.2 for the respiratory exchange ratio (RER) and 4.2 ± 0.8 for V (E). The corresponding values with MT were: 2.7 ± 0.3 for VO(2), 4.7 ± 0.4 for VCO(2), 3.3 ± 0.9 for RER and 4.8 ± 1.4 for V (E). Validity was acceptable except for small differences related to the determination of ventilation. The relative differences in relation to DBM at the powers including [Formula: see text] were similar for both sensors with the ranges being: +4 to -2 % for V (E), +5 to -3 % for VO(2) and +5 to -4 % for VCO(2) while RER did not differ at any power. The Moxus metabolic system shows high and adequate reliability and reasonable validity over a wide measurement range. At a few exercise levels, V (E) differed slightly from DBM, resulting in concomitant changes in VO(2) and VCO(2).
Various survey methods are used to monitor and manage ungulate popualations. The choice of optimal method depends on estimation accuracy, management objective and financial constraints. Here we compare estimates produced by four different methods for estimating population size, i.e. aerial counts, hunter observations, pellet group counts and cohort analysis. A Swedish moose Alces alces population was studied during 1973-2005 in the Grimso Wildlife Research Area (135 km(2)). The highest correlation was found between cohort analysis and aerial counts (r = 0.69. P < 0.05). and the hunter observations and the aerial counts (r = 0.76. P < 0.10). The different methods produced relatively consistent trends in population estimates over years. Pellet group counts prior to 1997 were not significantly correlated with the other methods. probably due to unrepresentative spatial sampling. A comparison of the aerial and pellet group counts in 2002 and 2006, showed that the average defecation rate was estimated at approximately 14 pellet groups per day per moose. Our results show the importance of having representative spatial sampling in pellet group surveys and indicate that hunter observations can be a useful tool for estimating long-term population trends even in moderately sized areas.
As the molecular marker density grows, there is a strong need in both genome-wide association studies and genomic selection to fit models with a large number of parameters. Here we present a computationally efficient generalized ridge regression (RR) algorithmfor situations where the number of parameters largely exceeds the number of observations. The computationally demanding parts of the method depend mainly on the number ofobservations and not the number of parameters. The algorithm was implemented in the R package bigRR based on the previously developed package hglm. Using such an approach, a heteroscedastic effects model (HEM) was also developed, implemented and tested. Theefficiency for different data sizes were evaluated via simulation. The method was tested for a bacteria-hypersensitive trait in a publicly available Arabidopsis dataset including 84 inbred lines and 216 130 SNPs. The computation of all the SNP effects required less than10 seconds using a single 2.7 GHz core. The advantage in run-time makes permutationtest feasible for such a whole-genome model, so that a genome-wide significance threshold can be obtained. HEM was found to be more robust than ordinary RR (a.k.a. SNPBLUP) in terms of QTL mapping, because SNP specific shrinkage was applied instead of acommon shrinkage. The proposed algorithm was also assessed for genomic evaluation and was shown to give better predictions than ordinary RR.
The rapid development of newtechnologies for large-scale analysis of genetic variation in the genomes of individuals and populations has presented statistical geneticists with a grand challenge to develop efficient methods for identifying the small proportion of all identified genetic polymorphisms that have effects on traits of interest. To address such a "large p small n" problem, we have developed a heteroscedastic effects model (HEM) that has been shown to be powerful in high-throughput genetic analyses. Here, we describe how this whole-genome model can also be utilized in chemometric analysis. As a proof of concept, we use HEM to predict analyte concentrations in silage using Fourier transform infrared spectroscopy signals. The results show that HEM often outperforms the classic methods and in addition to this presents a substantial computational advantage in the analyses of such high-dimensional data. The results thus show the value of taking an interdisciplinary approach to chemometric analysis and indicate that large-scale genomic models can be a promising new approach for chemometric analysis that deserve to be evaluated more by experts in the field. The software used for our analyses is freely available as an R package at http://cran.r-project.org/web/packages/bigRR/. Copyright (C) 2014 JohnWiley & Sons, Ltd.
The phenotypic effect of a gene is normally described by the mean-difference between alternative genotypes. A gene may, however, also influence the phenotype by causing a difference in variance between genotypes. Here, we reanalyze a publicly available Arabidopsis thaliana dataset [1] and show that genetic variance heterogeneity appears to be as common as normal additive effects on a genomewide scale. The study also develops theory to estimate the contributions of variance differences between genotypes to the phenotypic variance, and this is used to show that individual loci can explain more than 20% of the phenotypic variance. Two well-studied systems, cellular control of molybdenum level by the ion-transporter MOT1 and flowering-time regulation by the FRI-FLC expression network, and a novel association for Leaf serration are used to illustrate the contribution of major individual loci, expression pathways, and gene-by-environment interactions to the genetic variance heterogeneity.
The purpose of this correspondence is to discuss and clarify a few points about data transformation used in genome-wide association studies, especially for phenotypic variability. By commenting on the recent publication by Sun et al. in the American Journal of Human Genetics, we emphasize the importance of statistical power in detecting functional loci and the real meaning of the scale of the phenotype in practice.
Knowledge about the underlying genetic architecture of phenotypic traits is needed to understand and predict evolutionary dynamics. The number of causal loci, magnitude of the effects and location in the genome are, however, still largely unknown. Here, we use genome-wide single-nucleotide polymorphism (SNP) data from two large-scale data sets on house sparrows and collared flycatchers to examine the genetic architecture of different morphological traits (tarsus length, wing length, body mass, bill depth, bill length, total and visible badge size and white wing patches). Genomic heritabilities were estimated using relatedness calculated from SNPs. The proportion of variance captured by the SNPs (SNP-based heritability) was lower in house sparrows compared with collared flycatchers, as expected given marker density (6348 SNPs in house sparrows versus 38 689 SNPs in collared flycatchers). Indeed, after downsampling to similar SNP density and sample size, this estimate was no longer markedly different between species. Chromosome-partitioning analyses demonstrated that the proportion of variance explained by each chromosome was significantly positively related to the chromosome size for some traits and, generally, that larger chromosomes tended to explain proportionally more variation than smaller chromosomes. Finally, we found two genome-wide significant associations with very small-effect sizes. One SNP on chromosome 20 was associated with bill length in house sparrows and explained 1.2% of phenotypic variation (VP), and one SNP on chromosome 4 was associated with tarsus length in collared flycatchers (3% of VP). Although we cannot exclude the possibility of undetected large-effect loci, our results indicate a polygenic basis for morphological traits.
The depredation of semi-domesticated reindeer by large carnivores reflects an important human-wildlife conflict in Fennoscandia. Recent studies have revealed that brown bears (Ursus arctos) may kill substantial numbers of reindeer calves (Rangifer tarandus tarandus) in forest areas in Sweden. Several authors have suggested that predation risk is an important driver of habitat selection in wild Rangifer populations where predation is a limiting factor, but little is known about these mechanisms in semi-domesticated populations. We examined the habitat selection of female reindeer in relation to spatial and temporal variations in brown bear predation risk on the reindeer calving grounds and evaluated the simultaneous responses of brown bears and reindeer to landscape characteristics. We used GPS data from 110 reindeer years (97 individuals) and 29 brown bear years (19 individuals), from two reindeer herding districts in the forest area of northern Sweden. Our results did not indicate that reindeer alter their behavior in response to spatiotemporal variation in brown bear predation risk, on the scale of the calving range. Instead, we suggest that spatiotemporal behavioral adjustments by brown bears were the main driver of prey-predator interactions in our study system. Contrasting responses by brown bears and reindeer to clear-cuts and young forest indicate that forestry can influence species interactions and possibly yield negative consequences for the reindeer herd. Even if clear-cuts may be beneficial in terms of calf survival, logging activity will eventually cause greater abundance of young regenerating forest, reducing available reindeer habitats and increasing habitat preferred by brown bears. Domestication may have made semi-domesticated reindeer in Fennoscandia less adapted to cope with predators. Areal restrictions, limiting the opportunity for dispersion and escape, possibly make the calves more susceptible to predation. Also, a generally higher population density in semi-domesticated herds compared to wild populations can make dispersion a less efficient strategy and the reindeer calves easier prey. Overall, the lack of ability of the reindeer females to reduce brown bear encounter risk on the scale of the calving range is probably an important reason for the high brown bear predation rates on reindeer calves documented in our study areas.
Studien undersöker hur renar påverkas under konstruktionsfasen när vindkraftverk byggs. Studien följer uppförandet av två nya vindparker i Malå kommun i Västerbotten. Sammanlagt byggdes 18 vindkraftverk i Malå samebys kalvnings- och försommarland. Inventering av renspillning samt positioner från renar med GPS-halsband visar att konstruktionen av vindkraftsparkerna har påverkat renarnas användning av området. Analysen visar att renarna under tiden för byggnationen har sökt sig bort från området. Spillningsinventeringen och GPS-data visar också att renarna undviker kraftledningar och större vägar när de ska beta.
Rapport från kunskapsprogrammet Vindval.
Over the last decade, we have seen a massive increase in the construction of wind farms in northern Fennoscandia. Wind farms comprising hundreds of wind turbines are being built, with little knowledge of the possible cumulative adverse effects on the habitat use and migration of semi-domesticated free-ranging reindeer. We assessed how reindeer responded to wind farm construction in an already fragmented landscape, with specific reference to the effects on use of movement corridors and reindeer habitat selection. We used GPS-data from reindeer during calving and post-calving in the MalAyen reindeer herding community in Sweden. We analysed data from the pre-development years compared to the construction years of two relatively small wind farms. During construction of the wind farms, use of original migration routes and movement corridors within 2 km of development declined by 76 %. This decline in use corresponded to an increase in activity of the reindeer measured by increased step lengths within 0-5 km. The step length was highest nearest the development and declining with distance, as animals moved towards migration corridors and turned around or were observed in holding patterns while not crossing. During construction, reindeer avoided the wind farms at both regional and landscape scale of selection. The combined construction activities associated with even a few wind turbines combined with power lines and roads in or close to central movement corridors caused a reduction in the use of such corridors and grazing habitat and increased the fragmentation of the reindeer calving ranges.
To meet the expanding land use required for wind energy development, a better understanding of the effects on terrestrial animals' responses to such development is required. Using GPS-data from 50 freely ranging female reindeer (Rangifer tarandus) in the Malå reindeer herding community, Sweden, we determined reindeer calving sites and estimated reindeer habitat selection using resource selection functions (RSF). RSFs were estimated at both second- (selection of home range) and third-order (selection within home range) scale in relation to environmental variables, wind farm (WF) development phase (before construction, construction, and operation), distance to the WFs and at the second-order scale whether the wind turbines were in or out of sight of the reindeer. We found that the distance between reindeer calving site and WFs increased during the operation phase, compared to before construction. At both scales of selection, we found a significant decrease in habitat selection of areas in proximity of the WFs, in the same comparison. The results also revealed a shift in home range selection away from habitats where wind turbines became visible toward habitats where the wind turbines were obscured by topography (increase in use by 79% at 5 km). We interpret the reindeer shift in home range selection as an effect of the wind turbines per se. Using topography and land cover information together with the positions of wind turbines could therefore help identify sensitive habitats for reindeer and improve the planning and placement of WFs. In addition, we found that operation phase of these WFs had a stronger adverse impact on reindeer habitat selection than the construction phase. Thus, the continuous running of the wind turbines making a sound both day and night seemed to have disturbed the reindeer more than the sudden sounds and increased human activity during construction work.
BACKGROUND: Canalization is defined as the stability of a genotype against minor variations in both environment and genetics. Genetic variation in degree of canalization causes heterogeneity of within-family variance. The aims of this study are twofold: (1) quantify genetic heterogeneity of (within-family) residual variance in Atlantic salmon and (2) test whether the observed heterogeneity of (within-family) residual variance can be explained by simple scaling effects.
RESULTS: Analysis of body weight in Atlantic salmon using a double hierarchical generalized linear model (DHGLM) revealed substantial heterogeneity of within-family variance. The 95% prediction interval for within-family variance ranged from ~0.4 to 1.2 kg2, implying that the within-family variance of the most extreme high families is expected to be approximately three times larger than the extreme low families. For cross-sectional data, DHGLM with an animal mean sub-model resulted in severe bias, while a corresponding sire-dam model was appropriate. Heterogeneity of variance was not sensitive to Box-Cox transformations of phenotypes, which implies that heterogeneity of variance exists beyond what would be expected from simple scaling effects.
CONCLUSIONS: Substantial heterogeneity of within-family variance was found for body weight in Atlantic salmon. A tendency towards higher variance with higher means (scaling effects) was observed, but heterogeneity of within-family variance existed beyond what could be explained by simple scaling effects. For cross-sectional data, using the animal mean sub-model in the DHGLM resulted in biased estimates of variance components, which differed substantially both from a standard linear mean animal model and a sire-dam DHGLM model. Although genetic differences in canalization were observed, selection for increased canalization is difficult, because there is limited individual information for the variance sub-model, especially when based on cross-sectional data. Furthermore, potential macro-environmental changes (diet, climatic region, etc.) may make genetic heterogeneity of variance a less stable trait over time and space.
This work was part of the EU RobustMilk project. In this work package, we have focused on two aspects of robustness, micro- and macro-environmental sensitivity and applied these to somatic cell count (SCC), one aspect of milk quality. We showed that it is possible to combine both categorical and continuous descriptions of the environment in one analysis of genotype by environment interaction. We also developed a method to estimate genetic variation in residual variance and applied it to both simulated and a large field data set of dairy cattle. We showed that it is possible to estimate genetic variation in both micro- and macro-environmental sensitivity in the same data, but that there is a need for good data structure. In a dairy cattle example, this would mean at least 100 bulls with at least 100 daughters each. We also developed methods for improved genetic evaluation of SCC. We estimated genetic variance for some alternative SCC traits, both in an experimental herd data and in field data. Most of them were highly correlated with subclinical mastitis (>0.9) and clinical mastitis (0.7 to 0.8), and were also highly correlated with each other. We studied whether the fact that animals in different herds are differentially exposed to mastitis pathogens could be a reason for the low heritabilities for mastitis, but did not find strong evidence for that. We also created a new model to estimate breeding values not only for the probability of getting mastitis but also for recovering from it. In a progeny-testing situation, this approach resulted in accuracies of 0.75 and 0.4 for these two traits, respectively, which means that it is possible to also select for cows that recover more quickly if they get mastitis.
Key message: Gene expression analysis showed that prolonged short day (SD) treatment deepened dormancy and stimulated development of freezing tolerance of Picea abies seedlings. Prolonged SD treatment also caused later appearance of visible buds in autumn, reduced risks for reflushing, and promoted earlier spring bud break.
Context: Short day (SD) treatment of seedlings is a common practice in boreal forest tree nurseries to regulate shoot growth and prepare the seedlings for autumn planting or frozen storage. Aims The aim of this study was to examine responses of Norway spruce (Picea abies (L.) Karst.) to a range of SD treatments of different length and evaluate gene expression related to dormancy induction and development of freezing tolerance.
Methods: The seedlings were SD treated for 11 h a day during 7, 14, 21, or 28 days. Molecular tests were performed, and the expression profiles of dormancy and freezing tolerance- related genes were analyzed as well as determination of shoot growth, bud set, bud size, reflushing, dry matter content, and timing of spring bud break.
Results: The 7-day SD treatment was as effective as longer SD treatments in terminating apical shoot growth. However, short (7 days) SD treatment resulted in later activation of dormancy-related genes and of genes related to freezing tolerance compared to the longer treatments which had an impact on seedling phenology.
Conclusion: Gene expression analysis indicated an effective stimulus of dormancy-related genes when the SD treatment is prolonged for at least 1-2 weeks after shoot elongation has terminated and that seedlings thereafter are exposed to ambient outdoor climate conditions.
The ability of a population to adapt to changes in their living conditions, whether in nature or captivity, often depends on polymorphisms in multiple genes across the genome. In-depth studies of such polygenic adaptations are difficult in natural populations, but can be approached using the resources provided by artificial selection experiments. Here, we dissect the genetic mechanisms involved in long-term selection responses of the Virginia chicken lines, populations that after 40 generations of divergent selection for 56-day body weight display a 9-fold difference in the selected trait. In the F15 generation of an intercross between the divergent lines, 20 loci explained >60% of the additive genetic variance for the selected trait. We focused particularly on fine-mapping seven major QTL that replicated in this population and found that only two fine-mapped to single, bi-allelic loci; the other five contained linked loci, multiple alleles or were epistatic. This detailed dissection of the polygenic adaptations in the Virginia lines provides a deeper understanding of the range of different genome-wide mechanisms that have been involved in these long-term selection responses. The results illustrate that the genetic architecture of a highly polygenic trait can involve a broad range of genetic mechanisms, and that this can be the case even in a small population bred from founders with limited genetic diversity.


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As Theresa May, Prime Minister of the United Kingdom sets out to schedule her exit, nearly after three years, it may be a good time to review her economic legacy that, interestingly, does not seem to be distinguishable from her predecessor, David Cameron.
At one hand, the much talked about Brexit recession did not happen, more jobs were created and wages grew; but on the other hand, austerity continued, homes remained largely unaffordable and productivity growth remained appalling.
One of the direct and crucial impacts of the referendum has been that the UK economy today is 2% smaller than the pre-referendum forecast. This means a great deal of lost economic output. Another closely related shock has been related to the increase in import prices and decreased value of Great Britain Pound (GBP). Overall, economic growth in the UK has been 4.8% since 2016, which is lower than both Eurozone (5.5%) and the United States (7.3%). The future forecast is also similar as the country remains confused in the vicious circle of Brexit.
According to a team of experts at Bloomberg, uncertainty related to the impending exit from the EU has contributed towards a slower economy.
Workers' productivity grew merely by 0.5% last year, which could present a significant problem in the long-run since the country is going to be deprived of a certain portion of productive and skilled labor in the post-Brexit scenario. Amid financial difficulties, both Cameron and Theresa May pressed for different welfare changes, some of which included welfare cuts as well. These changes are going to make matters worse for many middle and lower income class families in the UK.
House affordability is another measure of the economy and there has been a negligible improvement under May's leadership of the country. Buying a house still seems to be out of reach for most young-earners and first-time buyers in most cities of the UK.
In spite of all these factors, there has been some good economic news as well. The UK has enjoyed an unprecedented level of a job boom in the last three years, as employment rates have been highest for nearly 150 years. Since Theresa May entered Downing Street, as much as 1 million more people have found work and unemployment rates have been lowest since the 1970s. However, some analysts see it as a short-term phenomenon as firms may feel safer to invest in labor than in capital in the time of uncertainty. as
As Theresa May prepares for her exit within the next few months, she still has to take certain crucial economic decisions, which will decide the actual fate of her economic legacy.


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Time to include videos in your email
Adding a video to email campaigns has been found to a positive effect on click-through definitely help to get response from prospects. Including videos in emails can really help businesses to build stronger relationships with their customers. Video content enables the audience of any given business to have a firsthand experience with that particular business. That is to say that video content enables the customers to hear, see and experience the business as a real thing. The very fact that videos add visual and audio effect goes a long way in ensuring engagement with prospects for the business in question.
So, when is it best to apply videos when sending those emails
There are some basic rules about email videos that businesses ought to know before they even send video emails. If these rules are not adhered to appropriately then everything else can go awry wrong.
Here below are some tips to help get you started with your first videos in your email marketing campaign.
Don't over use the video
Indeed videos powerful and attractive to most people, but this doesn't automatically mean that every email you send out needs to be accompanied with a video. It is not bad to use videos to reach your prospects but overdoing it might just let your prospects start to ignore your efforts. You can embed, apply Gifs and cinema graphs, but do this moderately.
Check out the file size
Video files usually occupy bigger space than audio files or text files and when they are combined the single file may become too large. A file that is too large will certainly have the subscribers wait for it to load. The sad part of this could be the subscriber closing the email altogether to avoid time wasting. This is why before you send any video email ensure that you compress the file with a good compression tool. Make the file to be smaller as possible so that it doesn't turn away your potential prospects.
Do comprehensive testing before sending
Even though videos are a great way to communicate with your customers or prospects, video may not be best for every audience out there. That said, it is best if you to do some testing to find out what works best. You can for instance test to see whether your email subscribers respond to your videos. You can go about this by creating 2 emails that look alike, one that contains a video and the other a still image. Find out which works best and opt for the one that you find great results with.
Do a preview of the email before sending
If you need professional videos in your emails, contact us here and let's start to boost your service using email!
How to stop their scroll? Ways to optimize your marketing video for Social News Feeds
With the rise in the use of technology in purchase of goods and services, video marketing is a must-use tool for many companies' promotional strategies. Social news feeds are a prime platform to enhance the visibility of a company and its products because of the audience they command.
To capture and keep the attention of a user for the duration of your video, it is important to keep a number of tips in mind. Remember that probably, your video will be "intruding" in a person's news feed when in truth; they are digging for different information.
Here are some strategies to help make your viewers curious about the content of your video so that they spare it a few seconds more:
Ensure that the video's first 3 seconds are effectively captivating
For a person quickly scrolling news feed, slightly less than two seconds is sufficient for them to decide whether they wish to view a given content further or not. Hence, you have a small window to make an impression enough to be given a few moments or be shunned and scrolled past.
The youthful population is the best target audience for this kind of video marketing
Teenagers, young people in their 20s, plus those in their early 30s are the biggest users of mobile devices; and mobile devices see the most exploration of social news feeds compared to computers. This therefore means that when creating the video, it should be fashioned to target this audience.
Much as your company might be dealing in products aimed at different demographics, for marketing videos to be posted to social news feeds, the focus should be on millennials. This might simply imply targeting those aspects of your products that are likely to be interesting to them.
10 to 15 seconds is the ideal, maximum length of the video
For a relatively unknown brand that is just making inroads in the digital marketing world, you do not want to run the risk of long, boring content. For your video to be effective, it ought to communicate the most important information in the first 80% of its full length.
Moreover, to ensure that viewers do not cut it off, keeping it short and to the point is the trick; 10 to 15 seconds is the tested length for successful promotional videos on news feeds.
Come up with new, refreshing content regularly
Sometimes, the best way to cultivate the most of such kinds of marketing is to create a growing relationship with your audience. With the same video, this can be impossible to achieve. Ensure that you focus on new, striking content to keep the audience you won the first time round and draw to new ones. Remember that this audience can only be turned into paying customers if you create a link between the products being marketed and their relevance to the viewers.
For your marketing video to achieve the intended success, you might need a few more tips to help it reach a larger audience. However, the 4 discussed above will help you make accurate first steps into this aspect of marketing. Talk to us of how BiscuitFish can help in produce your social media marketing short videos regularly to gain more of audiences and buyers .
Using a video series to promote your business can be a very effective strategy. Ultimately, by utilising video within your website or social media profiles, you can help to create a higher return on investment and work towards making your business more profitable through increased custom. More than half of marketers think that a video marketing series is the most effective way of promoting a brand. And here's few reason why it's time for you to get your video series for your business.
Video series help your business stand out
How many of your competitors are currently utilising video marketing? They may have the odd video here and there – but a video series takes things to the next level. Make your business stand out by promoting its self in a unique way.
Video series add vital credibility
Making your brand look and feel like a credible authority figure in your field can be difficult. That's where a video series step forward. It supercharges your credibility as people can see that you know what you are talking about over the whole series.
Video series can effectively summarise your businesses key messages
Your customers would probably prefer to view a succinct, two-minute video of your products or services in contrast to a lengthy 1000-word article. How about making a large part of your content in video? A video series allows you to do this and improve your page retention figures across the board.
Going viral can change the game
And all of these are based on your standard video marketing. If a series goes viral, then you add a large audience in a very short space of time. One video making a connection can lead to people subscribing and watching everything you put out in the series.
Video series work effectively with search engines
Search engines love videos because they favour engaging content. Resultantly, this can help drive more traffic to your website. By using video across multiple platforms such as business website, Facebook and YouTube, your marketing effectiveness can be boosted significantly. Again, you should think big here. A video series will put your website front and center with the search engines.
BiscuitFish provide a high quality, completely bespoke video marketing service whilst also being affordable. By offering a highly creative approach, we effectively promote your business whilst making the whole process easy for you. Passionate about video marketing, we are a highly experienced team and have produced 136 video marketing campaigns for past clients. If you have an idea for a video marketing project, or would simply like to discuss some options for your business, feel free to contact us today at firstname.lastname@example.com or use our on-line form. We look forward to hearing from you.
June 2018


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Tim Cook and "Imaginative CEOs"July 20th, 2017
Over the years, there has been a perception that Tim Cook is not quite the master of innovation Steve Jobs was and thus not suited to lead Apple. After all, it was Jobs who, after his return to Apple in late 1996, shepherded the introduction of the iMac, the iPod, the iPad, and, of course, the iPhone. And let's not forget the Mac and the original Apple computers during the early years.
A seasoned CEO would be lucky to manage even one of these achievements, let alone all of them. His very appearance at an Apple event, or during a keynote address, signaled insanely great. He had this aura about him that some regarded as a "reality distortion field," meaning he was such a talented salesperson that he could make you believe just about anything.
Legend has it that all or most of these products only exist because of Jobs' uniqueness, that no other CEO could possibly have done as well. Forgotten was the fact that he had his failures, too. So, although NeXT is remembered for its innovative, Unix-based operating system that formed the basis of today's macOS, the company failed at selling hardware, and was otherwise reduced to niche status before Apple acquired the company in 1996.
During his reign at Apple, Jobs had a few failures too, such as the Power Macintosh G4 Cube. Not everything he did was a smashing success. But none of it would have happened if Apple didn't have a talented design team for Jobs to browbeat into submission.
So the usual perception is that Tim Cook may seem like the more proper CEO what with the way he's handled investor issues, such as granting dividends, engaging in buybacks and other actions. His keynotes may not be quite as speculator as a Steve Jobs event, but he clearly rates higher than other CEOs.
But he's also regarded as the behind-the-scenes geek, managing Apple's supply chain and making it possible for all these products to be assembled efficiently and with a pretty high record of reliability.
That seems to be the case until you check out a report about the rating he's achieved courtesy of a supercomputer from, believe it or not, IBM. So according to a published report at CNET, IBM Watson's Personality Insights has delivered results that credit Tim Cook with being Silicon Valley's "most imaginative" leader.
Now this is not an all-inclusive conclusion based on a large base of executives. Indeed, it only consists of 11, based on data from Paysa, a job search company. The sampling included the CEOs from Amazon, Facebook, Google and Microsoft. The so-called Personality Insights report was based on "speeches, essays, books, transcripts of interviews and other forms of communication."
Amazon's Jeff Bezos was the runner-up.
Now I suppose, if you compare Cook to the heads of the largest tech companies, this survey may be right. But it's still a pretty narrow sampling. That means that some quite extraordinary company leaders might never rate inclusion in this computerized analysis despite their future prospects.
The long and short of it is that, perhaps, among a select group of CEOs, Cook rates really high. Perhaps that Watson conclusion is essentially correct. But you'd never believe a Gallup poll with such a small sampling.
While I have no doubt that Cook is highly imaginative, and he's certainly become a more confident performer as he continues to make public appearances, that doesn't mean he's the best of the breed. But it's also clear that Apple has done incredibly well under his leadership. You can argue that another executive might have had a sharper vision for our tech future. You might argue that Cook may have given too much power to the likes of Sir Jonathan Ive, and thus allowed him too many indulgences, such as a penchant for thinner and lighter above all else.
Or perhaps none of that is true. After all, Jobs basically made Ive a star. But since few know what Apple is actually doing behind the scenes, except what they tell us and what some former employees might be revealing (if true), most of the conclusions about the company's design process are little more than fake news. Or maybe corporate spin.
What is true is that Apple became the number one company on the planet, by market cap, under Cook. He took a smartphone and sold it to hundreds of millions of people in the years after Steve Jobs said he'd be happy if the iPhone had a market share of one percent.
As much as I'm skeptical about this computerized analysis, I'm just as skeptical of the people who claim Cook was the wrong choice to succeed Jobs at Apple because he's not a product person. So far, at least, he's done pretty well, and has become the most popular CEO on the planet. You can't complain about that, and you don't need a questionable computer survey to confirm that view.
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Clayne Crawford was born on April 20, 1978 in Clay, Alabama, USA. He is an actor and director, known for A Walk to Remember (2002), The Baytown Outlaws (2012) and The Perfect Host (2010). He is married to Sunshine Kiki Brown.
On the brink of the 2007 U.S. troop surge, two Recruiters face extreme pressures, realising that war isn't confined just to the battlefield.


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Air France, a global airline of French inspiration, with high standards and a caring attitude, turns the flight into a moment of real pleasure on all its daily operations in France, Europe and worldwide.
Since 2004, Air France and KLM Royal Dutch Airlines have formed a global air transport giant with a strong European base. The Group also offers cargo transport and aeronautical maintenance solutions.
Air France-KLM is the leading Group in terms of international traffic on departure from Europe. In 2015, it offers its customers access to a network covering 316 destinations in 115 countries thanks to its four brands Air France, KLM Royal Dutch Airlines, Transavia and HOP! Air France. With a fleet of 546 aircraft in operation and 87.4 million passengers carried in 2014, Air France-KLM operates up to 2,200 daily flights from its hubs at Paris-Charles de Gaulle and Amsterdam-Schiphol.
Its Flying Blue frequent flyer programme is one of the leaders in Europe with over 25 million members.
Air France-KLM and its partners Delta Air Lines and Alitalia operate the biggest trans-Atlantic joint-venture with over 250 daily flights.
Air France-KLM is also a member of the SkyTeam alliance which has 20 member airlines, offering customers access to a global network of over 16,320 daily flights to 1,052 destinations in 177 countries.


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Just came across some pics.. from The Big Chill Festival 2010 via the Big Chill Website......made me reminise over the time we went in 2007......I'm experiencing "Festival Cold Chicken".....
http://www.flickr.com/photos/thebigchillfestival/sets/72157624542890487/show/ (Copy this URL and enter into your address bar).
Biggabush by Big Chill Radio on Mixcloud
Don't forget your radio - Big Chill Radio will be broadcasting on 87.7FM all weekend long!
Bigger, better and brighter than ever, Big Chill Radio returns for another five solid days of wireless mayhem. From sun-up on Thursday morning, to tent-down on Monday morning, we'll be broadcasting to the entire site on 87.7fm day and night, bringing the flavour of the festival to your radio.
We'll bring you the best music from our DJs and special guests, news from around the site, interviews with artists, live sessions from bands and a whole load of random nonsense.
We'll be twittering like mad once again, so give us a shout on @bigchillradio with your dedications, photos and requests for tent pegs
Plus we'll let you know where you can hear all the stuff you've missed after the festival. So come and say 'hi' to us at our bijou studio in the Uptown field and keep it locked to 87.7fm
Thursday 5th August
8am: Bicycles, Tricycles, Testing…
9am: TBC
10am: TBC
11am: Mach V
Midday: Sherlock Ohms
1pm: Leggobeast
3pm: Biggabush
4pm: Bam Bam Sound
6pm: Peepshow Paddy and Count Skylarkin
8pm: Michael Cook
10pm: DJ Shepdog
Friday 6th August
Midnight: El Diablo's Social Club
2am: Big Daddy
4am: Ahmet Gunes
6am: Sherlock Ohms
8am: Sparky and Edd
10am: Chris Coco's Melodica
Midday: Live From The Stages
3pm: Big In Wigan with Seb White
5pm: Live From The Stages
7pm: BBC Hereford and Worcester
10pm: Live From The Stages
Saturday 7th August
1am: Luke Solomon
3am: Mixmaster Morris
6am: The Svelte One
8am: Mach V
10am: DJhistory's Balearic Breakfast Butty
Midday: Live From The Stages
1pm: Hospital Records Allstars
2pm: Christopher Tubbs (Heads Down)
3pm: Roy Shay
5pm: Live From The Stages
7pm: Craig Charles Funk & Soul Show
9pm: TBC
Sunday 8th August
1am: Futureboogie and Crazy P
4am: Max Cooper
6am: Mr Tom
8am: alucidnation
10am: TBC
Midday: Mikey D.O.N.
2pm: Fantasy Funk Band
3pm: Live From The Stages
4pm: The Pool with Matty J
7pm: Paul Jonas (Tru Thoughts)
Monday 9th August
1am: Special Guest
3am: Andrea and Mr Black
6am: Myles
8am: Ole' Smokey
10am: Scriv
Midday: Paul Noble
2pm: Closedown. Bye!


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Which is more important to you: a clean carpet – or a clean and healthy carpet? Yes, I assure you there is a big difference. Each carpet cleaning method has advantages and disadvantages. Some methods will get out only the dirt. Other methods will get out dirt and grease. Still others will get out virtually everything. And, to be sure, some are more expensive than others.
If all you want is a cheap, rinse-the-dirt-off-the-top cleaning – which you might find for around £15.00 per room – then I respectfully ask that you call another company. But if you want to protect your health – if you want to protect your investment in carpeting – if you want to protect your family from the countless bacteria, fungus, pollens and dust mites that reside in your carpet, then you're invited to call me.
The hot water unit we use is the most effective cleaning system available today. Likewise, it's one of the most expensive units on the market. But we bought this unit for a good reason: More and more families want the good-health benefits that come from having a fresh, clean carpet. Have you ever seen how dirty a little boy's trousers get when he plays outdoors? If you have, then you know you can brush off his trousers and make him think they're clean. The same is true for your carpet.
You can hire someone for £15.00-£40 who will brush off your carpeting and make you think its clean. Or, if you want the job done right I'll wash your carpets with hot water and detergent using my state of the art cleaning machine and you'll KNOW they're clean.
So if you want a thoroughly clean carpet – if you're willing to invest in your families good health – you're invited to call us. You'll receive a written estimate, at no cost or obligation, and if you give us the go-ahead, you're further protected with our
We want you to be super pleased – in fact, absolutely delighted – with every carpet and upholstery job we do. So every job comes with our iron-clad, risk free guarantee. What does this mean? Simply this: if you aren't pleased, you pay nothing. NOT ONE PENNY. Many companies don't guarantee their work – but we feel nothing is more important than your complete satisfaction. We stand behind every job 100%. If you ever have any questions or concerns about any of our technicians work, please call me right away.


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Photo Gallery with Description
Web+ has its own Photo Gallery Module which is using JQuery and Pretty Photo Gallery component. You can upload unlimited number of photos in your gallery with description. There is automatic slider also so you can view all photos in just single click. You can share your photo in Facebook and Twitter also.


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When it comes to outerwear, one of your closet staples should be a camel colored coat. A camel coat is timeless and easy to style. Its also the kind of coat that's ageless. I've seen teenagers style them with sneakers and mature women wear them to work and on the weekends. Although the camel coat is simple its truly the perfect piece to complete a look. As a plus size woman, I have found it hard to find plus size camel coats. Especially modern stylish ones.
Most plus size camel coats look frumpy and outdated. However, this year I spied quite a few stylish ones. What I love about plus size camel coats is that they can be worn in winter and in spring. When you think about camel colored coats, most people think about winter wool styles. I think if its within your budget you should have two. One for fall/winter and then an additional one for the spring season.
Why You Need A Camel Colored Coat
You need a camel coat in your wardrobe if you are looking for outerwear that goes with everything in your wardrobe. Black is not the only neutral color that goes with everything. Having a camel coat in your wardrobe will help you pull together and bring balance to printed ensembles. The most important reason you need a camel coat in your wardrobe is because you will wear it forever. It's timeless.
Personally, I have two spring plus size camel coats but didn't have a winter one. Thanks to Baacal by Cynthia Vincent, I got the perfect wool plus size camel coat. The fit is modern and it goes with just about everything in my closet. I wore it last month.
For a daytime look, I paired it with a striped red and white top, light washed distressed skinny jeans, and a pair of red suede pumps. I even went for a faux suede camel colored purse which had a gold chain strap. This look for me was perfect. It's the kind of look that you can run errands in, go to lunch in, or even go shopping in. This outfit would work whether I was wearing flats or sneakers.
What I really love about this Baacal coat is that its not too heavy. I can rock it without a scarf and still be warm or I can rock it with a scarf, hat, and gloves when the temps drop.
So hopefully I've sold you on why you need a camel coat in your wardrobe because I have a few options for you below. I've rounded up a few plus size camel coats that you can wear now and in spring.
All photos by: MJones Imaging
Plus Size Camel Coats
If you're looking for a professional chic plus size camel coat, checkout this belted maxi style from Ralph Lauren.
Since spring is right around the corner, this H&M soft trench would be an ideal option to wear to the office and on the weekends.
This wool cashmere blend peacoat from Calvin Klein plus can be worn now and even into early spring.
If you're looking for plus size camel coats that are longer, take a look at this maxi double breasted coat from ASOS Curve
For my fashion forward girls, this camel colored trench coat has puff sleeves.
City Chic Tailored Relaxed Coat is a nice light weight style for spring
When I think of a transitional camel coat, this one from Ralph Lauren comes to mind. It's more like a sweater coat.


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Since opening in Little Italy at the beginning of the year, the shop has been serving up some interesting flavor profiles.
They have scoops featuring local breweries like the Hopped Orange Creamsicle made with Modern Times' Thermometer Island barrel-aged Saison dosed with blood oranges. Last month it was kid-inspired flavors, such as Lots a' Naco with cheddar cheese ice cream, tomato jam, candied tortilla chips and avocado fudge.
Now April showers have made way for May's flower-inspired ice creams from co-founder and head ice cream maker Tyler Malek.
For the entire month, the Little Italy scoop shop will feature scoops highlighting such ingredients as anise, wildflower honey, elderberry and rose petal. The five flavor offerings will include:
Roasted Crumble with Toasted Anise
Vanilla bean ice cream layerd with rhubarb jam and studded with fresh-baked anise crumble for a crunchy, floral finish.
Wildflower Honey with Ricotta Walnut Lace Cookies
Honey ice cream with ricotta, tart lemon and pieces of homemade oat and walnut lace cookies frosted with buttery ricotta icing make for a refreshing, sweet and subtly rich treat.
Orange Blossom Sorbet with Edible Flowers
A bright and fruity sorbet made from organic blossoms, fresh-pressed orange juice, Tahitian vanilla and a dash of black pepper topped with an edible bouquet of peonies, borages, begonias and nasturtiums.
The Loose Leaf Wild Elderberry Tea
A naturally blue-hued ice cream with The Loose Leaf's Ultimate Elderberry tea, candied elderberries and dried blueberries.
Chocolate Rose Petal
Fresh rose petal ice cream accented by a fudge mole with prickly pears, cinnamon, cherry and anise.


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Quantum Q-Cloud offerings include:
Service and support is provided for every one of the Quantum Q-Cloud Services as described on this page.
Hardware & Software Services
Quantum Standard Hardware and Software Service Offerings
Some customers may have special support needs that are addressed through support plan options. These needs may involve better than Gold response, service at unattended sites and service at sites that require response from US Citizens
Severity Level Descriptions
Severity definitions and examples
SuperLoader 3
Service plans tailored for our SuperLoader 3 Autoloader product
Stand Alone Tape Drive
Service plans and warranties tailored for our stand-alone tape drives
Quantum Q-Cloud Protect for AWS Support
Quantum Q-Cloud Protect for AWS support is incorporated into the agreement the customer makes with Amazon. Support for the Quantum environment in the AWS Cloud operation is provided to the customer by Quantum with Quantum being the first point of contact. Support is available during normal business hours five days per week (5x9).
Quantum offers AWS implementation assistance to Quantum accounts, aiding them in setting up their AWS account and network and in the navigation of AWS terminology, acronyms and payment structure. Learn more


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How to Choose the Best Added Sugar Alternative for Your Business
Welcome to the 2nd article in our series of three, guiding your business through the different stages of making a change to your added sugar profile. If you're still not sure whether your business should be making that change though, then you might like to read our first article on the subject. In this article we'll be dealing with how you choose the right added sugar alternative for your business. To make things nice and simple, we've put the key considerations into a checklist format.
1) What about the stability of supply?
If you've been using added sugar for many years and have been sourcing it from the same supplier for all of this time, stability of supply may not have been something you've had to consider. However, added sugar alternatives come from different sources and geographical locations all across the world.
Of course, one of the biggest impacts on the stability of the supply chain can come from the Provenance of the company supplying it. How much do you know about the supplier you're about to entrust your business's needs to? What's their history, what other customers do they already work with and what measures do they have in place to minimise any potential disruption to supply?
2) Does the added sugar alternative you're considering qualify as 'natural'?
As we discussed in our first article, your customer base is likely to be increasingly concerned about their intake of added sugars. Because of this, there is a growing emphasis on replacing added sugar with alternatives that are not considered to be added sugar. Using ingredients that are seen as 'natural' can limit your potential exposure to negative customer sentiment or negative media coverage.
Your whole marketing strategy can hinge on the ingredients you opt for. For instance, it could be tempting to opt for an artificial sweetener, but consider how the impact this can have on the claims you'd be able to make about your product on its packaging and advertising. In the table below, you can see how important this has become in recent years.
3) What about other dietary aspects? Is your choice vegan?
Another aspect to take into account is how your choice of added sugar alternative performs in relation to other dietary factors. People who are interested in the issue of added sugar are more likely to be nutrition-savvy and interested in other forms of dietary exclusion.
As such, an example of an important question to ask could be whether your preferred option is vegan? For instance, being a product produced by animals (bees), honey is not classed as vegan. Would its inclusion unnecessarily narrow the potential market for your product?
4) Can your chosen supplier support on recipe and technical advice?
As we've already touched upon, alternatives to added sugar may not perform in exactly the same way as it when applied to a recipe or formula. Because of this, it's important to understand that there will be a period of experimentation and testing when it comes to reformulating your recipes. To make this process and smooth (and cost efficient) as possible, it can be crucial to have the right technical support.
5) What are the next steps for your business?
You'll notice that throughout this article we haven't specifically mentioned date products. Why not? Because we understand how important a decision this is for your business and we wanted to produce something that will be truly useful for you, not simply an advert for our own products.
However, we're 100% confident that we have the right answer for all of the important questions we've flagged and we'd love to talk them over with you. To find out more about how Beloved can support your business in reducing its added sugar profile, please contact us now to arrange a chat.


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Premium e mail and newsletter templates guaranteeing complete consistency across inboxes. Many will pay members to sign up and will pay more when you use them often and a lot more if you manage to get other folks to join as effectively. This way you will not only generate and send your newsletter but you will track your email newsletter opens and link clicks. The sales content material need to concentrate on the rewards that your product or service will supply and include three hyperlinks back to your site. Consequently, it is important that you make sure that you email marketing strategy has been designed to accommodate the wants of mobile customers. Facebook dan Twitter tersedia login, atau jika Anda ingin Anda juga dapat menggunakan e mail Anda untuk mendaftar. Devote time selecting a great design and improvement company as your life will be far simpler if you can stick with the very same men and women for the first couple of years.
Don't forget – your subscription, your e mail and any other information you may share with me are definitely confidential and I will never ever share them without having your understanding and permission! Anytime the internet copy newsletter files are moved to a new server, if they presently sit on the website's server and not in an e mail advertising and marketing system. If you do not have an archive, describe a sample newsletter and include an image.
I'd be genuinely curious to hear if you happen to be getting these spam/block troubles with an e-mail broadcast provider like these listed above. Some other Web Service Providers (ISPs) will only permit 5 MB files to enter their clients e mail mailboxes. Newsletters that are just extended advertisements never reduce it. If your newsletter only has announcements of new or enhanced goods or solutions, or specials that you happen to be operating, then you happen to be missing the boat fully.
E mail lists tend to be focused on interest groups, current client relationships and prior company relationships. 1 of my favourite components of my newsletter (and even so it does not appear each and every fortnight) is Hat Style Inspiration, which I only added about six months in. I like possessing a versatile strategy of content to suit what I have to write about. It is also properly equiped with publicity tools like email campturing and email list management.
One particular of the most important choices you will make will be which software program or service you use to run your site. When pushing out advertisements or other marketing that have an e-mail as the form of make contact with, use an e mail address that is only for that marketing and advertising, as your way of tracking. You undoubtedly can intermix generic titles into your e mail campaign, but use them as the exception not the rule.


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Posted on January 28, 2020
Sola Salon Studios
For many entrepreneurs, there's an instilled mentality to work hard. Hard work is likely how you've gotten where you are in your career. But working hard 24/7 can only last so long. Eventually, you'll start to feel run down, overwhelmed and deprived of self-care. To stay on top of your game, it's not always a matter of pushing harder. It's about working smarter!
These 5 tips will prevent mind and body fatigue, help drive more traffic to your social media and even help you generate more income!
Arrive 15-20 minutes before your first client. Arriving early to your studio to tear foils, prepare your color cart, fold laundry and return messages will set your day up for success. Being prepared for your day allows you to focus on your clients and not stress about studio housekeeping tasks. We've all torn foils in a tizzy and put ourselves behind. As a salon owner, it's time to bring your A-game.
Use scheduling software. There are so many apps out there that not only do appointment confirmations for you, but they also allow clients to schedule at their convenience. With personalized settings, these apps keep you in control while freeing up precious minutes in your day. Think about how much time you can save with 24/7 online booking: no more phone tag, no more listening to voicemails, and you'll even wake up in the morning to see new appointments. Imagine that, making money while you sleep! On top of that, when clients receive confirmations and appointment reminders, stylists receive fewer last-minute cancellations and no-shows. With this type of system in place, you can spend more time focusing on the guest in your chair.
Invest in a saddle stool. An adjustable stool can be used during cutting and color services to relieve pressure on your feet, knees and lower back. The saddle-shaped stools are especially helpful because they slightly shift the pelvis to support a healthy spinal curve during long workdays. Now, that's smart!
Sell retail. Selling retail products is the fastest way to increase your income by 10% to 200%. We know it can feel daunting at first, but a few simple tricks, such as handing the product to your guest after using it on them to allow them to feel it and smell it, will invite them to want to know more. It's all about education – your guests want to be shown how to recreate their look at home. Send them home with the products they need, and throw in a few samples if you want to introduce them to something new you're carrying. You literally have extra income sitting on your shelves. It's time to take that money to the bank!
Schedule your social media posts. Social media is the most effective way to connect with existing clients and build your clientele. However, posting on social media can get pushed to the back burner on a busy day. Using apps like Later and Hootsuite to schedule your social media posts keeps you and your salon visible even when you're in the middle of a nonstop salon day. By setting aside a few minutes early in the week to schedule your posts, you'll gain more followers and create more traffic to your salon's social media platforms.
There's no better time than now to start working smarter and not harder to continue making 2020 your best year yet!


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Sold Out
- Each order contains 1 steak
- Each steak is approx. 2-2.5 pounds
Due to natural variations in our cattle, shape, size, and/or weight of individual cuts may vary. It is normal to see slight variations in color depending on both the type of product and the aging process.
Due to natural variations in our cattle, shape, size, and/or weight of individual cuts may vary. It is normal to see slight variations in color depending on both the type of product and the aging process.
Double 8 Cattle Company is one of only a handful of farms raising 100% Fullblood Wagyu in the United States. 100% Fullblood Wagyu differ from most Wagyu being raised in the States, which often fall into the categories of Crossbred (F1, F2, F3) or Purebred (F4). The term "American Wagyu" has been adopted as marketing term for Wagyu beef that is Crossbred or Purebred Wagyu.
At Double 8 Cattle Company, we only raise 100% Fullblood Japanese Black Wagyu. Our cattle are direct descendants of Japanese Wagyu with unmixed ancestry. They are certified and registered with the American Wagyu Association, and their DNA can traced to their original ancestors in Japan. Our Wagyu have never been crossbred with other cattle breeds, such as Angus.
The recent steak order, skirt and flank is great.
This is, without a doubt, the best flank steak I have ever tasted. The ease at which I was able to prepare this exceptional cut of meat and the reactions I got from my family are priceless. I will be purchasing more from your company as soon as possible. As a retired Chef, I am a bit of a prima donna when it comes to the product I place before my family and friends. This flank steak did not disappoint. Keep up the good work.
The Wagyu flank steak we prepared was so tender and flavorful! Thank you, Double8 for a great product.
The steak is tender and juicy. I also bought a Flank from Kroger and compared. I cut both in half and marinated half and then just used steak seasoning on the other halves. Grill both at the same time. The verdict from the family was that the Wagyu steak was more tender and more juicy than the store bought one. The Wagyu has a little bit more of a beefy flavor also. Very pleased with it
I love this steak, tender, juicy, and full of flavor. Served it to my dad and brother, the three of us agreed it was the best steak we have ever had. Will definitely buy again and try other cuts. Highly recommend buying meat from double 8.


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Oh K!
Oh K! Coffee Bean Hydrogel Mask, 25g
Specially formulated to restore & refresh dewy radiance to lack-lustre skin, this Oh K! Coffee Bean Hydrogel Mask deeply rehydrates using the power of anti-oxidant rich Arabica Coffee Bean Extract.
This face shaped mask is made of hydrogel - which is super intensive, locking in moisture & maximising the absorption of its energising essence. Lie back & relax while your skin wakes up! Vegan-friendly.
How to Use / Benefits
2 Part Hydrogel Sheet Mask which is made up of the essence itself.
- Leaves the skin feeling energised
- Moisturising
- Coffee Arabica (Coffee) Seed extract – rich in antioxidants
Aqua (Water, Eau), Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Cetyl Ethylhexanoate, Coffea Arabica (Coffee) Seed Extract, Butylene Glycol, Ceratonia Siliqua (Carob) Gum, Chondrus Crispus (Carrageenan) Powder, Glyceryl Stearate, Cellulose Gum, Sodium Polyacrylate, Hydrogenated Polydecene, Coffea Arabica (Coffee) Seed Powder, Trideceth-6, Disodium EDTA, Phenoxyethanol.


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Well deep breath and here we go -our first ever blog. This all seems very daunting but we thought would just bite the bullet and dive in. Spring is on the way and its lovely to see more and more people out and about ,loads more people walking past the workshop heading up the Old… Continue Reading
Luxury Slate Products from the Lake District


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By Matt Wickstrom
LEXINGTON, Ky. – Musicians with new music hot off the presses infiltrate Wick's Picks live menu for August 19-25 led by Liz Cooper & The Stampede, Newtown, Houndmouth and Big Fresh. View the full live menu for next week here.
Tune into Wick's Picks every Monday from 9-11 a.m. on Lexington Community Radio. Upcoming guests include Big Fresh, Lyric Theatre Executive Director Donald Mason and Kevin Dalton on August 20 and Joslyn Hampton and Marty Charters of Joslyn & The Sweet Compression and Young-Eun Koepke of Petefest on August 27. Listen on the dial at WLXU 93.9 FM or online at lexingtoncommunityradio.org.