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Languedoc. Land of three kisses. Everyone knows that the French greet each other with kisses on the cheek. However, the French kissing custom can garner intense confusion for visiting foreigners. Like a secret code that only locals are privy to, the number of kisses exchanged varies based on geography, ranging anywhere from 1 to 5 (!!) kisses. Continue reading
End-of-vacation w(h)ining
Let us take a moment of silence to mark the end of a glorious two weeks of vacation. It was a brief staycation, cut short by my employer's requirement that I actually return to work. Total buzzkill. This time off will be sorely missed. But it's time to get back to saving the world, one translation at a time [translator's note: this may be a gross exaggeration].
Je vois la vie en rosé – part 2
Before reading on, be sure to read part 1 on rosé winemaking!!
If you've been to a liquor store in the last few months, you may have noticed a surge in rosés on display. Rosé is—for some reason—only a seasonal wine. It shows up on shelves in April and disappears by the end of the summer. This is why it is imperative to stock up if you find one you like. These wines are only made in limited quantities, so once a vintage is out of stock, that's it. You probably won't see it again until the spring of next year. That said, depending on how much you drink, you probably shouldn't get a whole case—these wines are for immediate consumption and are not typically meant to be aged.
As promised, here are my Summer 2016 rosé recommendations!Continue reading
California love…ish
Some of you may recall that I went to the California Wine Fair last Friday which, as it turns out, was a somewhat disappointing experience.
For one thing, my wine count went down from the 42 wines tasted at the Taste Ontario event to somewhere between 30-35. And since I always seem to be in some sort of internally-driven competition, this felt like a loss of some sort, even though the competition was against myself and myself alone (which would make me a winner as well, no?).
This was partly due to the fact that at 5 p.m., 2 hours after my arrival, the lights flickered on and off, indicating the end of the trade tasting. At this point the pourers began promptly removing bottles from the table, and the panic among tasters was palpable. What? That's it? It's over already? But we were just getting started!
Taste Ontario 2016 – Part one: Riesling, pinot and cab franc, oh my!
Today was a great wine day. I went to my first trade tasting! After getting back from Taste Ontario 2016, my initial thoughts were:
a) How sweet is it that I am now considered part of the trade!?
b) I really need business cards.
While I was there, I took lots of notes about the wines I tasted, but I also took lots of notes about my first impressions of a trade tasting, from the outsider/newbie's perspective. I felt a bit like an undercover spy, or an imposter. Luckily, after a few sips of wine I overcame that feeling.
- Even though this event gave me the opportunity to practice my spitting technique, originally this section was entitled "Obversations".
- The Ottawa wine world is small. Everyone seems to know each other (hence the feeling of being an outsider). As a result, I observed that the objective of the trade tasting for most is twofold: a) wine tasting; b) networking.
- In some ways, it sort of felt like being at a high school dance, except that I didn't know anyone (i.e. the stuff of teenager nightmares). There were definitely cliques: the sommelier/restaurant clique, from all the fancy restaurants around town – they tended to move together in packs, tasting together to decide if they wanted a wine for their restaurant's wine list. Then there was the media crowd – the journalists were pretty controlled while the radio people let loose. And then there were the oddballs – those of us who were there because we'd somehow managed to squeak through under the "media and trade" label.
Wines tasted
By my count, I tasted 42 wines in about 3 hours. Now, I must admit that Ontario is not by any stretch of the imagination one of my favourite wine regions, but I wholeheartedly support the Buy Local movement. And there are certain grape varieties that definitely lend themselves well to our Ontario terroir (namely riesling, chardonnay, pinot noir and cabernet franc, hence the title of this post). So without further ado, here were my favourites from that crew:
- Bachelder Niagara Chardonnay – this medium-bodied chardonnay has a beautiful oaky aroma, with a complex flavour profile. I kept getting rose water and orange flower. Lovely! Thomas Bachelder owns a successful trifecta of small craft wineries in beautiful wine regions: Niagara, Oregon and Bourgogne.
- Coffin Ridge 2015 Riesling Bone Dry – I had a great chat with Nyarai Cellars and Coffin Ridge winemaker Steve Byfield. He explained that Nyarai means "humility" in a South African dialect. And when I asked him how he rated his wines, he did indeed respond very humbly, saying that the wines are exceptionally balanced and food-friendly and allow for the terroir to really shine and express itself. This riesling was maybe one of the best I have ever tasted. It doesn't have that vinyl plastic taste I find so distracting, and focuses more on the fruity aspects: stone fruit like peach and apricot, as well as apple and a hint of citrus. In my notes, I wrote "Buy this". I'll likely take my own advice.
- Malivoire Moira Rosé 2015 – Malivoire's Ladybug rosé is a popular Ontario quaff in the summer, but the Moira rosé, made with 100% pinot noir, would be my preferred choice for a sunny day on the patio or out on the water. Sweet floral qualities on the nose, with red apple and candied fruit, yet still dry with medium acidity. My only wish is that they would sell it at the LCBO. I guess a trip to Niagara is in order.
That is certainly not the end of the list, but as you can imagine, I'm quite sleepy. Stay tuned for more thoughts on my first trade tasting, including more of my favourites and lessons learned.
P.S. I would be remiss if I did not thank @NatalieMacLean for alerting me to this event in the first place and getting me on the guestlist!


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Background Music Systems
We offer a large range of off the shelf 100v Line PA system packages for installation into bars, restaurants, schools, churches, Mosques and commercial properties. If you do not see what you require, or unsure of what you exactly require then do not hesitate to contact us. Our specialist audio support advisors can help at every stage of your installation, from offering initial guidance, full design with wiring diagrams, phone support during your installation to full installation carried out by one of our approved contractors.
So what are 100v Line PA Systems and how do they work?
100v Line or Constant Voltage speaker systems refer to networks of loudspeakers which are connected to an audio amplifier using step-up and step-down transformers to simplify impedance calculations and to minimize power loss over the speaker cables. In short it is a high impedance system that allows for multiple loudspeaker installation from a single amplifier, the amount of speakers used will depend on the power rating of the amplifier and the power tapping options of the loudspeaker.
For Example:
15 x Wall mount speaker/ceiling speaker @ 6 watt tap setting = 90w - This would require a minimum of 100w amplifier as the total speaker power rating should not exceed 90% of the amplifiers total power rating. The speakers can be installed into multiple zones (rooms) from a single zone amplifier with the use of attenuators (volume controller) to control volume in each zone, or alternatively installed with a multi zone amplifier such as the Clever Acoustics MA 4120MP 4 Zone Mixer Amplifier.


text: Children will play the most with items that hold their interest the most. That is why action & mini figures can be a great choice as all children have a favorite character or show. Figures allow children to learn and develop through open-ended, imaginative play. Through the use of figures, children ACTIVELY use their brains to create and re-create story lines from their favorite show with their favorite characters!


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FIFA 11 "French team"
French team
Composition: Lloris(VR)(Tottenham),Power(Stuttgart),Remi(Marcel),Varan(real),Umtiti(Barcelona),Pogba(MU),Conte(celsi),Matuidi(Juventus),Nzonzi(Sevilla),Griezmann(Atletico),Dembele(Barcelona)
Stock: Mandanda(VR)(Marcel),Areola(VR)(PSI),Mbappe(PSI),Cinema(PSI),Giru(celsi),Fekir(Lyon),Cowen(Marcel),Lamar(Monaco),Mendy(M),Hernandez(Atletico),Sidibe(Monaco),Talissa(Bavaria)
And again, another star team from me in France.Want said that is there I forget who wrote what other teams wanted to see Ecuador and the rest.Is there teams in the world which I previously laid out (Croatia,Belgium) I put again won't composition did not menyalsya practical. While working on the world teams. Download via CM11. 29.06.2018 updated.
FIFA 11 "French team"
Upload time: 6.09.2018
Size: 1.88 MB


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Sift: Cultivate a healthier relationship with the news
Sift is an experiment in news therapy to help you feel more informed and less anxious when you face the headlines. Download it from the App Store here.
It was the day after the 2016 presidential election, and Phil Libin sent a text to Chris Ploeg and Gabe Campodonico, experienced designers he'd worked with at Evernote. "That product idea you've been talking about," he told them, "is something we need to build. Now."
The product in question was one that Ploeg and Campodonico had mulled over for months as they observed the media coverage leading up to the election with growing concern. "The way people consumed news was terrible," said Campodonico. "Everyone was getting more and more polarized. That's something that had been happening for a while, but we were feeling it more at that time."
While the election created urgency for Campodonico and Ploeg's product idea, what they hoped to address was bigger than just one presidential election. They wanted to make a better way to understand news—a way that wouldn't drum up increasing levels of anxiety by scrolling through one "hot take" headline after another. That idea became Sift.
Sift takes a complex topic and provides a thorough breakdown of what's important to know. The first topic they've tackled is immigration policy in the U.S.
By presenting comprehensive fact-checked coverage, Sift avoids the alarm-raising media storms that often arise around these matters, and instead lets readers gather thoroughly-vetted information at their own pace. The reduction of anxiety-triggering news intake is something they're calling news therapy.
"A lot of people in America feel overwhelmed by the news," said Kelly Chen, writer and editor at Sift. "Keeping up with the news is anxiety-driven. Sift is an experiment to see if that experience could be more nuanced."
The app guides readers through a deck of digital cards, each of which presents a distilled point backed by sourced research. The user can choose between the Economy deck, which explains the complex economic factors at play in immigration policy in the U.S., or the Society deck, which focuses on the social and historical context.
While swiping, every so often a brief challenge will come up; for example, "Match each group with the year you think they were granted citizenship in the U.S." Getting correct answers doesn't earn the user any rewards, because it's not about accruing points—it's about providing an interactive way to encourage users to think about what they're consuming and how it aligns with their preconceived ideas.
"The goal of Sift is for people to get away from headlines that just talk about what happened, and more into foundational concepts of why they've happened," said Campodonico.
Ploeg added, "From a general content perspective, we try to not be hyperbolic or triggering for people, but we're also not trying to pretend like everything's fine. Immigration policy needs nuanced, thoughtful coverage, not people shouting about it."
Sift bills itself as "an experiment in news therapy." The "experiment" part of that tagline is meant to invite users to participate in its development, and to signal that the product that's out today is only the first iteration of what it may ultimately become. To that end, users are able to provide direct feedback to Sift's creators within the app.
Design-driven founders
Sift's co-founders are not journalists, so their outsiders' perspective on the news gave them a clear view for reassessing what worked and what didn't in media consumption. They both have design backgrounds; Campodonico was the head of product design at Evernote, and Ploeg was a design manager on that team.
What they've built with Sift is a design-driven take on how people can consume information. Campodonico explained the need for that approach: "We knew we were digging into a level of detail you don't get while reading the daily headlines. That's a lot to ask of people with busy schedules, so we had to think of a form that would allow a wider spectrum of people to engage more deeply with this information. That was a product design problem."
After building the scaffolding of what they wanted the product to be, they brought in Chen, a journalist who came from CNN and the Huffington Post, to help them flesh out the content.
"This process wouldn't have happened in a newsroom, because Chris and Gabe, as designers, think so differently," said Chen. "As journalists, we think news first. We want to get the accurate info and throw it out into the world. Chris and Gabe think of the user first, and what they know and want to know, and all those considerations made it a lot harder when we were designing it, but ultimately made for a better product. We're setting up expectations for users to want to learn more."
Get a mental workout
This experiment in news therapy is meant to help people improve the mindset they have when taking in the news, but it also asks that users put in the effort do that in a methodical way. "We won't take all your anxiety away—you have to put in the work too," explained Chen. Or as Ploeg likes to say, "We're not a spa, we're a gym."
As exercise strengthens the body, so too can this kind of deep-dive fortify the mind. Enjoy that cognitive runner's high.
Sift is available for download today on the App Store. Visit their website to learn more.
AI needs cooperation, not an arms race
Writing in the New York Times recently, venture capitalist Kai-Fu Lee signaled an important, oncoming change in the way we think about…


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Iron single-atom catalyst in form of iron-nitrogen-carbon structure possesses the excellent catalytic activity in various chemical reactions. However, exploring a sustainable and stable single-atom metal catalyst still faces a great challenge due to low yield and complicated synthesis. Here, we report a functional multi-wall carbon nanotubes modified with iron phthalocyanine molecules via a liquid chemical reaction and realize the performance of similar single-atom catalysis for oxygen reduction reaction. A serial of characterizations strongly imply the structure change of iron phthalocyanine molecule and its close recombination with multi-wall carbon nanotubes, which are in favor of ORR catalysis. Compared to commercial platinum-carbon catalyst, composites exhibit superior activity for oxygen reduction reaction with higher half-wave potential (0.86 V), lower Tafel slope (38 mV dec−1), higher limiting current density and excellent electrochemical stability. The corresponding Zinc-air battery also presents higher maximum power density and discharge stability. Therefore, these findings provide a facile route to synthesize a highly efficient non-precious metal carbon-based catalyst.
Journal of Power Sources – Elsevier
Published: Jun 15, 2018
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- Key spec
- Paddler weight (minimum): 65kg
- Boat length: 5.2M
- Beam: 53cm
- Constructions: All
- Stability: 10 (very stable)
0 1 2 3 4 5 6 7 8 9 10
Now made in the UK!
With low-profile racing lines and a well-balanced hull form, the Tempest delivers stability and performance. It comes as standard with our quick-adjusting universal sliding seat (available in a choice of heights) and our usual range of footrest options including the club-friendly sliding system.
The Tempest was designed with optimal stability in mind, making it the perfect choice for newcomers to the sport. For the more experienced, it's a cost-effective second choice for the colder seasons, when the risk of going for an unexpected swim is unthinkable.
Despite the relatively large size of this K1, it remains surprisingly agile in the water and it is able to maintain a fast cruising speed with minimal effort. The larger paddler in particular, will appreciate the spacious cockpit. The sleek low profile gives a racing appearance without compromising practicality and the high-displacement hull shape means it is suitable for a large range of paddler weights.
Available in white, with a choice of three deck flashes (red, blue and black), the sporty styling of the Tempest means it looks great from the bank and from the cockpit so you can paddle with confidence. What's more, the hull conforms to the Paddleability racing rules, making it one of the best-value and best-performing contenders in the field.
+ Sleek racing styling
+ Suitable for beginners to the sport
+ Quick adjusting universal seat with a choice of height options
Construction options
Kirton boats are built by hand so we can make any boat in any construction - the choice is yours. We have have no frills options for the budget-conscious, alongside elite light-weight constructions for top-ranking professionals that need the best. Of course, there are many options in-between too, to suit every pocket and every need. We can make the boat stiff for sprint racing, or more flexible so it'll withstand the rigors of marathon and recreational use. Whatever your needs we can make the perfect boat for you. Click to see our construction list. Also check out our leg measurement chart, to guarantee a perfect fit.
Customisation options
We specialise in making boats that are perfect for you and your paddling style. Here's a selection of popular customisation options and accessories that you can request when ordering your Kirton boat. Click for details of contact us for more information.


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Is there anything more irritating than the sound of a rattling window? Not only is the sound a constant source of annoyance, but it can also signal other problems like energy leaking out of your home, which can lead to skyrocketing energy bills. Before scheduling a window replacement, though, it's important to understand what might be causing the rattling, as in some cases it might be a problem you could fix easily on your own.
You are here: Home / Archives for loose glass


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The world shows and gives us many different images of happiness, buy this, go here, do this, etc. but if we are constantly searching for external happiness how do you know when you have found it?
I personally prefer to find happiness within me, in my experience this is me standing in my power.
This is me in love, but am I happy? I think there are moments in life that we are truly happy. Sometimes our memories make us smile and happiness does exist. But how do you know when you are happy, or must someone tell you and educate you about it? Can you desire happiness, like you desire a pair of shoes? These are questions I ask myself all the time. Happiness is finding the contentment inside of you. Feeling love with yourself, others, friends and family.
Happiness though requires complete honesty about who you are and what you are wanting in life.
So I say to myself, when exploring the vast lands of Secondlife. Let it go, just be yourself and love what you are here for and the adventures that it brings. Don't be saddened if you can't find that loved one. Enjoy and experience what it has to offer.
Wearing the stunning and delicate designs of Gizza from the Fiera Saviad Spring Fashion Fair on now. I bring to you the destination for today:-
Destination: Fiera Spring Fashion Fair
Outfit: - GizzA - Lolita Dress [Beige] (New from Fiera Saviad Spring Fashion Fair)
Hair: - TRUTH HAIR Harriet - light blondes (New)
Necklace: Cae :: Into The Woods :: Collection
Skin: - Glam Affair - Zara - America
Eyes: - IKON Spectral Eyes - Evening
Eyelashes:-.::WoW::. Diva Lashes
Lips: - Glam Affair - Romy - Lips Gloss
Cheeks: - {Dead Apples} Tintable
Hands: -Slink Av Enhance Hands Female - Casual
Pose: - (Wicca's Wardrobe) WW - Big Hat Fun 005 (New from Saviad Spring Fashion Fair)


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News & Articles
2017 Christmas Lunch
We are pleased to report that our Residents had a wonderful Christmas Lunch on 9 December 2017, with 98 in attendance. Our traditional lunch included a hot carvery of beef and turkey and all the trimmings. Following lunch our Directors and Chaplain led the singing of Christmas carols.
All Residents at the event were entered into a draw to win a cookbook and selection of special teas. The prize was kindly donated by Vanessa Weddell, Head of Community Engagement & Fundraising.


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Video today Tamilselvi 20-12-2019 Full Episode. Watch online today's latest Tamilselvi 20-12-2019 Tamil TV complete video stream for free only on at TamilDhool TV. Watch TamilTV program Tamilselvi 20th December 2019 video episode. Tamil Show Tamilselvi 20-12-2019 Full Episode Video Online.Tamilselvi 20/12/2019 | Tamilselvi 20-12-2019 TamilDhool | Tamilselvi 20.12.2019 Sun TV Video Online | Tamilselvi 20th December 2019 | Watch Tamilselvi 20 Dec 2019 | Tamilselvi 20 December 2019 Latest Episode in HD on TamilDhool Tv.
Tamilselvi 20-12-2019 on Sun TV
Show Tamilselvi is a tv drama serial, telecasted on Sun TV. Stream all latest episodes in HD Quality and also catch all the latest happenings, promos releated to show at one place.
Video Source: Standard Video License
Program: Tamilselvi
Telecast Date: 20-December-2019


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The valley of Ait Bouguemez (also called the Happy Valley) is located in the heart of the Central and High Atlas mountains. During this trip you will discover the Berber world! Are you ready to discover a new culture?
PRICE PER PERSON: From 385 €
|N° Days
|N° Person
|1 – 2 Person
|Group 3 – 5
|Group 6 – 10
|Group 11 – 15
|8 Days
7 Nights
|Accommodation Type
|On request
|580 €/person
|430 €/person
|385 €/person
|On request
|730 €/person
|620 €/person
|530 €/person
DEPARTURE/ARRIVAL: Marrakech
Comfortable sportswear and hiking boots, hat, fleece jacket, sunscreen, sunglasses, headtorch, water bottle, sleeping bag.
Certified English-speaking Guide Accommodation: 2 in 3* hotel + 5 in lodges
All transfers Cooking equipment and the services of the best cook of Morocco
All meals (vegetarians options are possible) Services of the mule handlers (mules will carry the backpacks)
Meals in Marrakech International flights
Bottled water Travel insurance
Personal purchases Tips
Day 1: Arrival in Marrakech - Home
Transfer from the airport to your accommodation. The first evening you will be able to spend by yourself and explore the vibrant life of Marrakech.
Day 2: Marrakech- Azilal – Ait Bougumez valley ( 1900 m )
After the delicious breakfast, we will hit the road to get to the High Atlas Azilal and the valley of Ait Bougumez (5H drive) We will visit Arouss village and discover the diversity of the local architecture.
Day 3: Gite Tamazirte ( 1900 m )- Arouss Gorges - Ikkis Tulip ( 2200 m )
Today is the first trekking day: you will go to Ikiss and enjoy the panoramic view of the M'goun peak (4067 m) while having lunch. In the afternoon we will go to the gorge then come back to Ikkis to spend the night. 5H walk
Day 4: Ikkis Tulip ( 2200 m ) - Igoudamn - Ait Imi ( 1850 m )
After breakfast we will go to Jebel Igoudamen to have a picnic in nature then we will continue walking the trail to the village of Ait Imi where we will be hosted at a local family's house for the night. 6H walk
Day 5: Ait Imi ( 1850 m ) - Ibakliwoune - Ifrane ( 2000 m )
Today we climb the Jebel Adazen taking in the panoramic views then climb a bit more to the village of Ifran to stay at a local family's house for the night. 4H walk
Day 6: Ait Bougumez - Marrakech
Today we will say goodbye to the valley leaving behind the majestic peaks of the Atlas mountains and the friendly people we got to know then return to Marrakech, the Red City. Optional – see the highest waterfalls of Morocco on the way back. 5H30 drive
Day 7: Visit of Marrakech - Medina
Today is a day to enjoy the culture and history of the Red city and the former capital of Morocco. We will visit the medina, palaces, souks and other special places of the city.
Day 8: Transfer to the airport
We wish you a pleasant journey back home and look forward to seeing you again1
Tour Reviews
Very happy with the services from Morocco ectours. Our guide Mohamed, who helped us with the organisation was very responsive, efficient and provided alot of useful detailed information about & for the trip.I can strongly assure you that you will not go wrong if you book a Tour with Morocco Ecotours.
We had a lovely day with gide Mohammed Alla. We learned a lot about the moroccan culture and had a beautiful walk around the Ouzoud waterfalls. Mohammed was helpfull, relaxed and very friendly.


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Additional Amenities
Myrtle Beach Kids Activities
Summer fun has never been better than this. Crown Reef Resort offers seasonal summer activities for the whole family! Just head to the pool deck where you can meet Salty, the friendliest shark mascot from the sea. Our friendly staff has summer fun ready for all ages like volleyball, corn hole, pool games, and more! Select activities will meet in the Activity Room, located on the Lobby Level Room 36. There's something fun and exciting to do every day at our kid-friendly resort in Myrtle Beach!
Resort activities vary day-to-day Monday thru Saturday like jewelry making, water balloon toss, arts and crafts, limbo contests, tye dye, candy bingo and so much more! Crown Reef Resort also features tons of poolside entertainment that all ages will enjoy, including a magician and poolside DJ.
See the current schedule for Myrtle Beach kids activities and special events here.
Quick & Easy Beach Access
Only steps away from our oceanfront pool deck is expansive beachfront waiting to be enjoyed. Soak in the warm sun and splash in the refreshing Atlantic waters. Build sandcastles and collect seashells along the tide. With Crown Reef Resort's unrestricted beach access, you'll have no problem going back and forth between a day at the beach and some time by the pool at our kid-friendly resort in Myrtle Beach. Rent a chair from the local lifeguards or bring your own. It's time you take that long-awaited Myrtle Beach getaway!
Sun Deck
Warm up on Crown Reef Beach Resort and Waterpark's extensive sun deck. There's plenty of lounge chairs to choose from, with two levels of oceanfront sun deck available to all guests. Salty's Sun Deck provides a serene escape and Breeze's Deck boasts beautiful views of the beachfront. Special events can also be reserved on the sun deck – the sun deck provides 2,068 square feet of space and can accommodate up to 150 guests. What are you waiting for? Find your perfect spot on the Crown Reef Resort sun deck.
Fitness Center
Vacation doesn't mean you have to skip your workout routine. Crown Reef Resort has a new state-of-the-art fitness center, located on the Lobby Level in Tower 2 of the resort.
The air-conditioned fitness center includes two stationary cycles, two elliptical cross-trainers, two treadmills, free weight dumbbells, adjustable pulley station, leg press, balance trainer, four flat-screen TVs, and much more!
The fitness center is open from 6:30 am to 10:30 pm (hours subject to change) and is free for guests to use.


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The cufflink has been a part of a businessperson's dress shirt or blouse for quite a while now. Most of the time, it is nothing more than decoration...a fancy substitute for a button. Well, the next time that you get dressed up for that important meeting, you can impress your colleagues and clients with these nifty cufflinks that are MORE than just decoration. They not only let you carry valuable data around with you, but can even hook you up to the Internet!
Each cufflink has a hidden component that you access by sliding it out of its base. In one of them is a 2GB USB drive where you can store your important documents for quick retrieval. The other contains a small wireless router that you can plug into any computer connected to the Internet, creating a mobile hotspot that you and others nearby can use to get online from laptops or other devices.
The prestige of carrying around such technological marvels on your wrist does come with a somewhat hefty price tag. Expect to pay $250 USD for the set. You can find the full story on these cufflinks, and where to find them, at http://www.gizmag.com/wi-fi-usb-cufflinks/21232.
To follow all of our blog postings, please be sure to subscribe by clicking the "Join this site" button, or by submitting an email address in the "Follow by Email" box along the right margin. And if you see something that particularly interests you, be sure to share it on your Facebook, Twitter, or other social media pages using the icons provided.
You can sign up for an account with SpotON3D by going to https://spoton3d.com/register/, or through your Facebook page at https://apps.facebook.com/webworlds/.


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Translational Diagnostics
In molecular pathological diagnostics amplicon-based parallel sequencing has been used up to date. By this method, therapeutic genes and gene segments can be amplified, enriched and subsequently sequenced by means of multiplex-PCR. This method can also be used on fragmented and chemically modified DNA from formalin-fixed, paraffin-embedded (FFPE) tissue.
The disadvantage of the amplicon-based parallel sequencing is that this method does not routinely detect chromosomal aberrations such as gene fusions and translocations on DNA level. These aberrations are still widely analysed by FISH and RT-PCR or immunohistochemistry. The main disadvantage of these methods is that a specific assay has to be performed for each individual chromosomal aberration. As a result, these methods are time-consuming, a lot of starting material is needed and in particular FISH is very cost-intensive. The development of new parallel sequencing approaches to detect all therapeutically relevant genomic changes in a single assay is an ongoing process. Currently, various technologies are being evaluated for the detection of chromosomal aberrations.
On a DNA level, hybridization-based parallel sequencing is used for the simultaneous detection of somatic gene mutations, gene fusions, and copy number changes. Here, DNA is shared and adapters are ligated. Custom designed, biotinylated DNA probes are hybridised to target sequences to allow for sequence enrichment using streptavidin beads. Finally, libraries containing the target sequences are sequenced on platforms like NextSeq 500 from Illumina.
On a RNA level, RNA-based parallel sequencing assay have already been developed for the detection of gene fusions. Here, specific primers are used for the detection of known fusions and previously unknown fusions can be detected by an 5 '/ 3' imbalance score. These assays can also be used for the simultaneous detection of several fusion events. However, it is not clear whether somatic gene mutations, such as point mutations, small deletions, insertions or duplications, are reliably detected with this approach. For detection of somatic gene mutations, an additional DNA-based assay is currently required. In addition, the extraction of intact RNA from FFPE material is challenging.
The aim of this work is to evaluate and compare the new parallel sequencing strategies for molecular pathological diagnostics and to implement the most suitable methods into routine diagnostics.
In this research project, a new hybridization-based parallel sequencing approach will be established for the detection of genomic aberrations in sarcomas on FFPE material. This assay will be used to address research questions in the field of targeted therapies. Additionally, this assay will be implemented into the routine molecular pathological diagnostics in order to promote, among other things, the establishment of targeted therapeutic strategies within the university hospital in the field of sarcomas. Our long-term goal is to strengthen the infrastructure for molecular targeted therapies in clinical oncology. By publishing the approach in a peer-reviewed journal, the sarcoma panel and the experience gained will be available for other molecular pathological departments.
NanoString's nCounter analysis technology is based on the marking of specific target regions using color-coded hybridization probes. This results in a wide variety of possible applications, e.g. 1) gene expression analyses, 2) SNV determination and 3) detections of chromosomal fusions. The analysis is performed on RNA, extracted from fresh tissue, cell lysate or FFPE-fixed tumor tissue. A custom-designed panel is available for the detection of fusion genes in lung tumors, which can detect chromosomal aberrations in the genes ALK-, RET-, ROS1 and NTRK1, -2, -3. On the one hand specific fusion events and their associated translocation partners can be identified (specific probes). On the other hand, the detection of fusions with an unknown translocation partner is also possible.
(Lung-) Fusions Panel
Specific Lung Fusion probes detect the following fusions:
5´/3´ Expression of imbalanced probe pairs can detect fusion events with unknown translocation partners:
|8 imbalanced probes
|8 imbalanced probes
|8 imbalanced probes
|8 imbalanced probes
|8 imbalanced probes
|8 imbalanced probes
Therapy of patients with breast cancer at an early stage starts with an accurate assessment of the Risk of Recurrence (ROR). The Prosigna assay was developed on the basis of the PAM50 gene signature and allows the stratification of tumors into different intrinsic subtypes, carrying different biological and clinical features. In addition, the test determines a proliferation value, i.e. the expression of different genes of the proliferative signaling pathway. In combination with clinical data on tumor size and number of positive lymph nodes, prognostic information for therapy decision can be made. The risk-of-recurrence score (ROR score) is given on a scale from 0-100 and has been proven to be prognostically significant for the period of endocrine treatment over 5 years. You will find detailed information on the test and costs on the manufacturer's homepage
The cooperation of Ruhr University Bochum with the lung cancer center Bonn / Rhein-Sieg and the Cologne Institute of Pathology has successfully applied for a grant for the project FP 339 "Development of protein-analytic procedures for the identification of candidate markers to support the (early) diagnosis of asbestos-associated pulmonary and pleural tumors". The project is focusing on the development and verification of the numerous results achieved in the initial project. In addition, an extension necessary for mechanistic verification is added at the levels of genomics and transcriptomics. The Institute of Pathology has many years of expertise in the analysis of genomic aberrations in lung tumors. In the future, not only people from the general population, but above all also employees, will be able to benefit from the results obtained in the course of the subsequent screening if it is possible to establish early identification markers that can reliably diagnose lung tumors in a treatable stage. Tissues from 150 operative pulmonary carcinomas are to be cryopreserved every year, and whole blood, plasma and saliva samples are collected from the same patients. In surgical specimens, tumor-free marginal tissue should also be considered. Further, lymph node biopsies from 50 additional patients will be obtained. In addition to the establishment of biomarkers for early detection, the basis for personalized cancer therapy can be laid by the mechanistic findings to be expected in the project, thus also benefiting from tertiary prevention. A long-term goal is the implementation of the blood test diagnostics for personalized cancer therapy in lung tumors. In particular, it is crucial whether genomic changes in the cancerous tissue can be detected in the plasma in early, curatively resectable lung tumors. If this question can be answered in a positive way, it is possible to significantly improve the specificity of cancer early diagnosis of suspicious pulmonary arteries detected by CT screening, and to use this methodology in the monitoring of risk persons.
Biomarker Research
HR23b as a predictive biomarker for HDAC inhibitor based therapy in soft tissue sarcomas
Histone modifications have been shown to be key players in epigenetic alterations and are often dysregulated in cancer. Therefore, histone deacetylases (HDAC) seem to be promising therapeutic targets for HDAC inhibitor based therapy in cancer. HR23b, the UV excision repair protein Rad23 homolog B, was revealed as a potential biomarker for the sensitivity to HDAC inhibitor (HDACi) based therapy in cutaneous T-cell lymphoma. Furthermore, in hepatocellular carcinoma HR23b expression was associated with stable disease under HDAC inhibitor therapy. Therefore, we aimed at evaluating HR23b as a candidate biomarker for HDACi response in solid tumors (sarcomas and gastrointestinal stromal tumors (GIST), melanomas and adenocarcinoma of the lung).
Our previous studies have shown that sarcomas differ significantly concerning HR23b protein expression. Sensitivity to the HDACi vorinostat correlated significantly with HR23b protein expression. Immunohistochemical prevalence screening in clinical samples of relevant adult-type tumors revealed that 12.5% of sarcomas (among them malignant peripheral nerve sheath tumors, pleomorphic liposarcomas, leiomyosarcomas, dedifferentiated liposarcomas, synovial sarcomas and angiosarcomas) and 23.2% of GIST show high HR23b expression (Ihle et al., JCP, 2015).
To expand these observations to other solid tumors the expression of HR23b is analyzed in melanoma and adenocarcinoma of the lung using immunohistochemistry. Cell lines are examined for sensitivity to HDACi based therapy in relation to their HR23b expression. Furthermore, the expression of different HDACs is determined in correlation with the inhibitory effect of HDACi in all tumor entities. To address the question of the HR23b function in the context of HDACi sensitivity stable specific knock-down and overexpression of HR23b is conducted by CRISPR/Cas and the effects on sensitivity, viability, apoptosis and signal transduction are determined. Murine mesenchymal tumors are induced to investigate the effect of functional HR23b depletion or overexpression on the sensitivity towards HDACi treatment in vivo.


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Light Session 4j
Most people think light platform is only for services as we are very good at it. However, it can be used to build web applications that support Mobile Native and Single Page applications. To provide Single Sign-On and High availability, we need to support multiple instances of server running and session replication among them. Light-session-4j is designed for this and it support in-memory, Hazelcast, Redis and JDBC for session replication.


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Only Top Rated Companies!
At Sense Financial Services, we feature life insurance company ratings based on financial strength and ability to meet obligations to their policyholders. Only the top life insurance companies are presented to you.
|ING Reliastar Life
|Lincoln National Life Insurance Company
|West Coast Life Insurance Company
|Fidelity Life Assurance Company
|Vantis Life Insurance CompanySince its inception (1942), the Company's primary goal has been to provide families with affordable life insurance and annuity products. Vantis Life has more than $4.9 billion of life insurance in force, and nearly $674 million of annuities in force. The Company prides itself on providing simple, easy-to-afford products to hard working American families and supporting these products with attentive and personal customer service.
*Life Insurance Company Ratings
For the latest rating, access www.ambest.com


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In the case of the bologna, Gaffney is perplexed. She took down the price as $2.49. But her computer tells her that on her last visit the price was $1.99. After some investigating, Gaffney realizes she grabbed the wrong item this time -- the higher-priced all-beef light bologna.
We like to think that measures like the CPI are simply out there and true. The bologna shows us, however, that there is measurement error involved (even if it is likely to be small) and that the measure is stochastic. (Not to talk about the conceptualization problem: What is it that a typical person consumes.)


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Speaking with my beauty therapist i enquired into the benefits of having a facial peel which is performed with a mild form of acid that removes the top layers of dead skin from the face in order to reveal a beautiful baby fresh complexion but my excitement was soon quashed when my rosacea and sensitive skin made me an unsuitable candidate.


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Taken from the official Copperhead Facebook page, here is our first look at the star of the film, Billy Campbell, who stepped in to replace Jason Patric just last week for the lead role of Abner Beech. This is an nice in-camera shot, as you can see him preparing for a scene in front of a green screen:
Some background on Campbell: The Golden Globe-nominated actor is a veteran in his own right, appearing in nearly 60 films and television shows, including regular roles on The 4400, The O.C, Crime Story, and Dynasty, as well as starring roles in Moon Over Miami, Once and Again and AMC's The Killing. As for film, he will be teaming up with director Ron Maxwell for the third time, as he was Lt. Pitzer in Gettysburg, and Maj. Gen. George Pickett in Gods and Generals. We would like to wish him the best of luck in this role!
For all the latest news, updates, pictures, and historical essays regarding the movie Copperhead, please click here to be directed to the special page we have set up on this blog for it. Also, make sure to check out their official website!


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Eight members of the newly appointed State Board of Elections and Ethics Enforcement will meet for the first time at 8 a.m. Wednesday.
Josh Lawson, general counsel for the agency, tweeted out notice of the meeting Monday morning.
Gov. Roy Cooper on Friday appointed members to the Board, which he has left vacant for the past year while pursuing litigation over the laws restructuring the agency. Litigation is ongoing.
The eight members consist of four Republicans and four Democrats, and there is a ninth seat that remains open for a member unaffiliated with either party.
At its first meeting, the Board is expected to name two nominees for Cooper to appoint to the vacant seat. The meeting is open to the public and will take place at 430 N. Salisbury Street.


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Lab Partnering Service Discovery
Use the LPS faceted search filters, or search by keywords, to narrow your results.
Showing 1 - 3 of 3
Areas of Expertise
He is a laboratory fellow and director of the Fuel Cycle Science and Technology Division at Idaho National Laboratory (INL). His primary focus is directing research and development of advanced technologies for spent nuclear fuel recycling and other chemical separation applications. He also serves as the national technical director for the U.S. Department of Energy (DOE) Nuclear Technology Research and Development Material Recovery and Waste Form Development Program and is also the director of the Glenn T. Seaborg Institute at INL. He has 35 years of experience in chemical separation technologies involving spent nuclear fuel and radioactive waste. He holds bachelor's and master's degrees in chemical engineering from Montana State University and a doctorate degree in chemical engineering from Khlopin Radium Institute in St. Petersburg, Russia. He has published over 200 journal articles, reports and conference proceedings, and awarded 23 U.S. patents and six Russian patents, as well as received numerous awards, including an R&D 100 Award. He serves on the editorial board for the journal, Solvent Extraction and Ion Exchange. He is a fellow of the American Institute of Chemical Engineers and the American Nuclear Society and the founder of an endowed chemical engineering scholarship at the University of Idaho. He has served on numerous international conference scientific advisory boards and technical program committees.
Areas of Expertise
She has more than 30 years of experience in theoretical and computational chemistry. She develops new methods and algorithms for high performance computational chemistry as well as applying those techniques to both basic and applied research. Her current application interests are rare earth and heavy element chemistry, separations, catalysis, aerosol formation, cellulose degradation, and photochemistry. Much of her research interests involve large, collaborative efforts between scientists in multiple fields working together to solve difficult scientific challenges. She is a distinguished professor in the Chemistry Department of Iowa State University. Prior to joining Ames Laboratory, she worked at Pacific Northwest National Laboratory as the lead for the NWChem development group and the Visualization and User Services Group. She also worked at the Wright Patterson Air Force Base in technology transfer and training. She received her bachelor's in chemistry, mathematics, and computer science from Minot State University and her doctorate in physical chemistry from Iowa State University.
Areas of Expertise
He is a distinguished scientist for the Aqueous Separations and Radiochemistry Department at Idaho National Laboratory. He has expertise in nuclear fuel separations (aqueous and pyrochemical), high-level waste treatment, decontamination, nuclear processing off-gas treatment, and low-level waste treatment. His areas of decontamination expertise include chemical, strippable coatings and laser decontamination methods. In 1991, he began the study of decontamination of stainless steel nuclear fuel reprocessing equipment and waste minimization. In 2004, he began developing decontamination technologies to remediate radioactive contamination from a dirty bomb for the Defense Advanced Research Projects Agency. His expertise in decontamination and decommissioning (D&D) was recognized by the International Atomic Energy Agency (IAEA) with a consultancy on decommissioning spent fuel pools and as a teacher for the IAEA D&D courses. He holds seven patents and won an R&D 100 Award in 2011. He is a founding member of the National Analytical Management Program (NAMP) and continues to serve as the High Dose/Hot Cell Subcommittee chairman. He serves as a member of the Waste Management Symposia Program Advisory Committee for the last 12 years and annually as the session chairman for Novel Decontamination Techniques. He is also a member of the ASTM Subcommittee E10.03, Radiological Protection for Decontamination and Decommissioning of Nuclear Facilities and Components.


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Nicole Kholodnov
VP of Clinical Operations • New York
Nicole Kholodnov is the VP of Clinical Operations at Parsley Health, where she heads clinical operations, as well as membership experience and revenue planning. Prior to joining Parsley Health, Nicole oversaw Clinical Operations at Oscar Health, a venture-backed startup operating in 6 states using technology to simplify health insurance. As a founding member of the Care Delivery vertical, she set up and oversaw operations for Oscar's primary care practice, the Oscar Center, and virtual tele-health offering in-house. In a previous role, Nicole built and scaled the team responsible for determining insurance products' coverage and corresponding claims adjudication. Before Oscar, Nicole was a senior management consultant at Oliver Wyman, working primarily in their health and life sciences practice. Nicole is a graduate of Harvard University. In her spare time, Nicole enjoys running (first marathon, NYC 2017!), spending time outdoors (hiking, skiing, biking), reading medical case studies, and all things pasta.
Frequently asked questions
Can Parsley Health be my primary care physician?
We are considered a primary care practice, so we treat all conditions that a primary care doctor would. We are not specialists. However, if you need to see an OBGYN, cardiologist, or surgeon, for example, you will be referred appropriately. The costs associated with the services provided by specialists or any other healthcare provider outside of Parsley Health are not covered by your Parsley Health membership. Beyond visits, the primary mode of communication with our care team is messaging. We answer quickly during the week (within 24 - 48 hours) and always have a doctor on call to address urgent issues on weekends and holidays. We are often able to take care of acute issues without the need for a visit. A few points to remember about your Parsley Health membership: 1. We do not take insurance. However, we can provide paperwork for you to submit for out-of-network reimbursement from your insurance. You can also pay for your membership using FSA/HSA dollars. 2. We are not available for same-day emergency appointments. 3. If you have a medical emergency, we recommend that you visit urgent care or an ER.
Is Parsley Health covered by insurance?
We do not accept any form of insurance. Parsley Health is classified as a primary care practice, but insurance companies don't recognize our membership model. After each medical visit, a lab manager can provide a superbill that you can submit to insurance for out-of-network reimbursement. Many members choose to pay for their plans using FSA/HSA dollars.
What is included with my plan?
What's Included: Doctor's visit(s) Health coaching visit(s) Online billing and scheduling Unlimited messaging with your care team through an online patient portal (Parsley Membership only) Prescriptions for medications and supplements (Parsley Membership only) In addition to our services, you'll have access to: Our online supplement store at a discounted price Members-only events Exclusive access to and deals from our wellness partners - our favorite places to sweat, stretch, zen, and shop!
Do I need health insurance if I have a Parsley Health membership?
A Parsley Health membership does not replace health insurance. We advise all members to maintain a separate health insurance plan of their choosing. For blood work, insurance frequently offers full coverage. Please also note that the Affordable Care Act (Obamacare) includes a requirement that all U.S. citizens purchase health insurance. A Parsley Health membership does not meet this requirement.
Is testing included in my membership fee? What costs can I expect to see?
Your doctor will work with you to customize testing orders based on your health needs and personal preferences. Costs for blood work and specialty tests are not included in the membership price. Blood work is usually covered by insurance. Specialty tests range in cost from $100 - $350. These tests, however, are completely optional.
What types of diagnostic testing does Parsley Health perform?
We offer both standard blood work and in-depth specialty testing to help construct a comprehensive picture of your health and better inform treatment. A personalized testing plan will be recommended by your doctor. All tests, however, are optional. Some of our most frequently prescribed specialty tests assess allergies, cortisol, genetics, microbiome health, and toxic metal levels.


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The Ideal Home: Arts Thursday 27 December 2018
HOME is the theme of Arts Thursday on 27th December 2018.
The Ideal Home is a phrase that conjures up a long-running English exhibition that showcases the latest ideas, designs and products for the home.
The Ideal Home exhibition at Penrith Regional Gallery and the Powerhouse Museum showcases some of the innovations and products that wowed homeowners in the 20th century – radiograms, early washing machines and domestic technologies and includes 70 objects from the Museum of Applied Arts and Sciences' collection.
The exhibition also explores recent issues associated with the home – such as domestic violence and domestic waste, as well as homelessness through the work of contemporary Australian artists, Cope ST Collective: Matthew Cooper and Colin Kinchela, Karla Dickens, Victoria Garcia, Richard Goodwin, Blake Griffiths, Eliza Gosse, eX de Medici and Catherine O'Donnell
Meet exhibition MAAS Head of Curatorial Jacqui Strecker and Penrith Regional Gallery Director Lee-Anne Hall speaking with Maisy Stapleton at the Penrith Regional Gallery.
For further information:
The Ideal Home exhibition and Penrith Regional Gallery and the Lewers Bequest: https://www.penrithregionalgallery.com.au/
The Ideal Home at the Powerhouse Museum: https://maas.museum/event/idealhome/
The whole program can be heard on demand through the Arts Thursday page http://eastsidefm.org/arts/artsthursday/ by clicking on the date 27 December 2018.
And watch out for individual podcasts.
Join Maisy Stapleton fortnightly from 10:30 to noon on Arts Thursday for conversations, behind-the-scenes views and coverage of Sydney's arts events, stories and issues.


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VIVES surprises with its amazing stand
Once again the fair for the construction and ceramics sectors starts another year in Valencia. From today until Friday 5, Cevisama opens its doors to launch the latest developments in tiles.
For this occasion, VIVES has prepared an original stand in order to surprise visitors and professionals. Following the philosophy of its new Cottage collection, Vives has transformed its space at the fair in a fusion of tradition and modernity. Different styles and designs which blend together and achieve a stunning aesthetic balance.
We are expecting five days of great anticipation in which Vives Azulejos y Gres shows off its Fusion collection too, presented at the last edition of Cersaie 2015, in Italy, with great success. VIVES also expands its Basic Collection, the refreshing and functional porcelain tile series with new formats, textures and decorations.
You can visit our stand located in Pavilion 1/ Level 3 - STAND B28


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Beginners Guides If learn to trade forex books you are totally new to the trading scene then watch this great video by Professor Shiller of Yale University who introduces the main ideas of options : Education for beginners: Types of Trades How. In this situation, four losing trades will blow the account. Click Call / Put or Buy / Sell Will the asset value rise or fall? The major regulators currently include: Financial Conduct Authority ( FCA ) UK regulator Cyprus Securities and Exchange Commission ( CySec ) Cyprus Regulator, often passported throughout the EU, under MiFID Commodity Futures Trading Commission ( cftc ) US regulator Australian Securities. Esma Recently, esma (European Securities and Markets Authority) moved to ban the sale and marketing of binary options in the.
Most Accurate Easy Binary options Balanced System (Trading
Choose a Broker Options fraud has been a significant problem in the past. Otherwise, a trader has to endure a drawdown if a trade takes an adverse turn in order to give it room to turn profitable. Where binaries are traded on an exchange, this is mitigated however. Any moves by the Federal reserve for example, will feed into binary markets immediately, just as you would expect. Enter the size of the trade or investment Decide if the value will rise or fall and place a put or call The steps above will be the same at every single broker. Different trading platforms label their trading buttons different, some even switch between Buy/Sell and Call/Put. Asset Lists The number and diversity of assets you can trade varies from broker to broker. Elsewhere in Europe, like in France, for instance, regulators have prohibited the advertising of risky financial products like binary options. For example, if a trader wants to buy a contract, he knows in advance, what he stands to gain and what he will lose if the trade is out-of-the-money. Is binary options trading legal in the USA? Note with a touch option, that the trade can close before the expiry time if the price level is touched before the option expires, then the Touch option will payout immediately, regardless of whether the price moves away from the touch level afterwards. Some unregulated firms are responsible and honest, but many are not.
Trading taxes in India - how trading profit is taxed by IRS
Introduction Video How to Trade. A No Touch is the exact opposite of the Touch. Currency binary options are mostly limited to major currency pairs like EUR/USD, GBP/USD and USD/YEN. The very advantage of spot trading is its very same failure the expansion of profits exponentially from 1 point in price. Set the size of the trade Remember 100 of the investment is at risk so consider the trade amount carefully. Trending Pages, top 10 Tips. The second choice is to use a firm regulated by bodies outside of the. Advantages of, binary, trading. More layers of complexity can be added, but when trading equities the simple Up/Down trade type remains the most popular. First, the trader sets two price targets to form a price range.
From, home as a, copywriter
The significant pairs are often easier to predict, follow and more familiar to everyone. The ban is only designed to protect retail investors. In 2005, the company introduced Box Options, a foreign exchange binary options mix of binary options and corridor options. Are, binary, options, gambling? In/Out, Range or Boundary This option sets a high figure and low figure. United States, expertOption, mobile Apps, binomo, india.
This reflects changes envisaged in the Markets in Financial Instruments Directive (MiFID). The most you will find offered by a broker tends to be between 40-70. That offering was subsequently abandoned, with the company referring to regulations imposed under the Dodd-Frank Act in the United States and similar initiatives in other major financial centers. Others drop the phrases put and call altogether. Certain provinces, such as Quebec, are planning radical measures like a ban on most types of binary options. T has educated traders globally since 2011 and all our articles are written by professionals who make a living in the finance industry. The largest market of them all is the currency (or forex) market which is a firm favourite with many. Binary options brokers will generally have their trading platform open when the market of the underlying asset is open. Traders should not foreign exchange binary options let anyone trade on their behalf.
That said, there is only a certain number that is usually"d by brokers due to their liquidity. Halal Brokers if you are one of the growing number of Muslim traders. Some will include locking in an initial deposit (in addition to the bonus funds) until a high volume of trades have been made. In forex trading this lack of discipline is the #1 cause for failure to most traders as they will simply hold losing positions for longer periods of time and cut winning positions in shorter periods of time. All the best in your trading, oanda forum moderator A rather polite and elusive reply.
Does Binary Options Work?
I know Im not the Only one whom has Interest. So if trading the nyse, Nasdaq, DOW or S P, the assets will be open to trade during the same hours as those markets are open. Canada, which is an important market for oanda, has speeded up its efforts to tackle binary options fraud. Investing, financial Analysis, definition of Currency, binary. If the trader expects the price to go up (the Up or High trade he purchases a call option. Put and Call, options, are, binary, options a Scam? For instance, trading gold, a commodity with an intra-day volatility of up to 10,000 pips in times of high volatility, requires trading capital in tens of thousands of dollars. The price of oil, or the Apple stock price, for example. Some brokers offer foreign exchange binary options all three types, while others offer two, and there are those that offer only one variety. Pick one from the recommended brokers list, where only brokers that have shown themselves to be trustworthy are included. He then purchases an option to predict if the price will stay within the price range/tunnel until expiration (In) or if the price will breakout of the price range in either direction (Out). To get started trading you first need a regulated broker account (or licensed). .
Binary Options Broker Opteck
Binary, options to the platform. There is no leverage to contend with, and phenomena such as slippage and price re"s have no effect on binary option trade outcomes. Option Types The most common type of binary option is the simple Up/Down trade. There are three types of trades. # binary options, #Financial Conduct Authority (FCA), #Gambling Commission, #Markets in Financial Instruments Directive (MiFID) II, #oanda. Binary trading does not have to be complicated, but as with any topic you can educate yourself to be an expert and perfect your skills. The average spot forex trader only looks at price, which means he is only looking in one direction before crossing the street. I got into Forex by way of Forexs Cousin. References and Further Reading A Study of Optimal Stock and Options Strategies (Dash, Mihir and., Kavitha and.M., Deepa and., Sindhu, 2007) Is There Money to Be Made Investing in Options : A Historical Perspective (Doran, James. Operators making such claims are very likely to be untrustworthy. High/Low Also called the Up/Down binary trade, the essence is to predict if the market price of the asset will end up higher or lower than the strike price (the selected target price) before the expiration. Do not let anyone trade for you. Some operators will funnel new customer to a broker they partner with, so the person has no idea who their account is with. .
Spot Forex vs Binary Trading These are two different alternatives, traded with two different psychologies, but both can make sense as investment tools. Which Are The Best Trading Strategies? Some brokers do not offer truly helpful trading tools such as charts and features for technical analysis to their clients. Top Brokers Broker Regulated Min Deposit Payouts Bonus Nadex 250 100 » Visit RaceOption Deposit match bonus » Visit BinaryCent Bonus on ANY 1st Deposit » Visit Brokers are filtered based on your location (United States). The top eight traded currencies are the United States dollar (USD euro (EUR British pound (GBP Canadian dollar (CAD Swiss Franc (CHF New Zealand dollar (NZD Australian dollar (AUD) and Japanese YEN (JPY). What is a Currency Pair, as the name might suggest, it is a pair of currencies where one is the 'bid' unit and one the &apos"'. These safeguards are in place to protect US residents, but trading is absolutely legal. Each of these has different variations. Normally you would only employ the Double Touch trade when there is intense market volatility and prices are expected to take out several price levels. You can choose to predict the outcome of the USD against the GBP where the USD is the base currency or the other way around, GBP/USD, where the GBP becomes the base unit. Not every stock will be available though, but generally you can choose from about 25 to 100 popular stocks, such as Google and Apple. Binary options means, put very simply, a trade where the outcome is a binary Yes/No answer.
Forex trading has no central market, and as such USD pairs can generally be traded around the clock for 5 days a week. Signals and Other Services For further reading on signals and reviews of different services go to the signals page. Select the asset or market to trade Assets lists are huge, and cover Commodities, Stocks, Cryptocurrency, Forex or Indices. Simplicity A binary trade outcome is based on just one parameter: direction. There are however, different types of option. Binary options are really a means to speculate on currencies, rather than an investment. See our broker lists for regulated or trusted brokers in your region. The only exception is where a Touch option has hit a preset level prior to expiry. The risk and reward is known in advance and this structured payoff is one of the attractions.
What is a lot in, forex market and how it is calculated?
Some broker label buttons differently. Currency trading is one of the foreign exchange binary options oldest methods of trading in existence and today is the largest and most liquid market in the world. No-one, not even the best professional forex traders, can know what will happen to an exchange rate in the next 10 minutes. Conversely, a trader making a well researched trade will ensure they have done all they can to avoid relying on good fortune. Bonuses and Offers if you want to make sure you get extra money to trade with, or other promotions and offers.
Accessibility In order to trade the highly volatile forex or commodities markets, a trader has to have a reasonable amount of money as trading capital. Downloads are quick, and traders can sign up via the mobile site as well. This is changing for the better though, as operators mature and become aware of the need for these tools to attract traders. If a trader thinks the underlying price will go up in value, they can open a call. Strategies and Guides We have a lot of detailed guides and strategy articles for both general education and specialized trading techniques. Also be sure to add the Trading Formats such as 60 Sec, 2Min, 5 Min, High/Low, In/Out, Boundary, 20 Min Et Cetera. Traders want to react immediately to news events and market updates, so brokers provide the tools for clients to trade wherever they are.


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The children from Pocklington Infant School visited Uncleby over three days in October.
The focus for the Year 1 children was The Gingerbread Man, they have been looking at traditional stories in school. The children took part in a variety of activities. Mrs Wray made gingerbread men with the children in the kitchen – the boys and girls really enjoyed eating them at the end and thought of lots of brilliant adjectives! The children acted out the story in the courtyard then they used the stones to make a gingerbread man picture. The final activity was planting a seed in a pot, the children took them back to school and will plant them in the school garden.
Foundation stage children enjoyed looking at the cows and calves and having a sit on Farmer Mike's tractor. They walked to the sheep with Mrs Wray and Farmer Geoff told them about the cattle and the sheepdogs. They also learnt about where the food in the shops come from.
It was raining when the Year 2 children came but they still managed to have an enjoyable and educational day. Their focus was harvest and apples especially. Mrs Wray made apple crumble, the children had been writing instructions in school and could remember the ingredients and some of the weights! In the classroom the children used a machine to core and peel apples they also used an apple press to make juice. They enjoyed tasting it too. The other activity was making an 'apple model'. There were some fantastic ideas and very intricate models.
Lots of learning and fun activities took place over the three days.
Mrs Moore " A lovely day as usual. The children loved the dale walk on such a beautiful day. The best bit however was eating their gingerbread man."
Miss Fry " The children really enjoyed the visit, there were lots of new things for them to learn and they really enjoyed looking at the machinery"
Kayleigh Stutt " This is the BEST school trip EVER"


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November 27, 2009
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Kamloops Cruises to Gold Medal
By Janice Huckin
Victoria BC (ISN) – The 2012 Jr. B Lacrosse provincials wrapped up at Bear Mountain Arena Sunday and it was the Kamloops Venom capturing gold, going undefeated through the tournament and defeating the Delta Islanders in the final match-up. Delta takes home silver and in the bronze medal game, Saanich got their only win of the weekend in the bronze medal game and it came against their archrivals, the Westshore Bears.
The bronze medal was up first, game 7 of the tournament. Westshore had won the earlier round robin game between the two and it was the Bears taking the first lead, Nolan Ryan going end-to-end and scoring unassisted on the power play at 7:01. Saanich got on the board a little over 5 minutes later. This was also a special teams tally but came shorthanded as Trevor Hansen cut across in front and beat Westshore's starting goaltender Cody Cook at 12:15. That was all the scoring in the opening period but there was a lot more action of the extra curricular variety. We had earlier discussed that 6 games had been played with no fights – that shutout streak ended at the 19:32 mark and I guess if you would have predicted a fight, it probably have come in a game between these two fierce rivals. In any event, several majors for fighting, face-masking, and a few misconducts saw 5 players in total ejected. Shots on goal favoured the Bears by a 15-6 margin but things were tied up on the scoreboard.
Westshore started things off in the second period, just 1:41 in, Sam Chiasson getting a breakaway and putting the host team up by a goal, that tally coming shorthanded. It took almost 13 minutes before the next goal was scored but it started a 3-goal run for the Saanich squad. Craig King scored unassisted at 14:15 going over top of Cook to tie things up. Just 9 seconds later, off the ensuing faceoff it was Quinton Hamilton putting the Tigers up by a goal and at 15:18, Ethan Garland found the back of the net. That put the Bears down by a pair and also marked the end to Cook's stint in net as he was replaced by Will Chiasson. The Bears got within a goal right away, Kelly Schiarizza scoring at 15:33, as he powered to the front of the net. That was how the second period ended, with Saanich holding a 1-goal lead by a 4-3 score. Shots on goal favoured the Tigers 17-14 after 40 minutes.
The Bears were unable to solve Jared Jackson in the Saanich net through the final 30 minutes as the Tigers put three on the board. Mason Pynn scored at 6:55 and the final two goals came into the empty net as Westshore had their goaltender on the bench for the extra attacker. Both came from Ethan Garland. Garland finished with the hat trick and 1 assist for the victors. Quinton Hamilton and Craig King each chipped in a goal and 1 assist with other goals coming from Mason Pynn and Trvor Hansen. Westshore got singles from Nolan Ryan, Sam Chiasson and Kelly Schiarizza.
On to the gold medal game in which the undefeated Kamloops Venom took on the 2-1 Delta Islanders. It was another low-scoring battle that saw great goaltending at both ends as Kamloops jumped out to a 3-2 first period lead. Jimmy Latin started things off for the Venom at the 5:17 mark but Delta replied right way as Ethan Jones scored unassisted just 28 seconds later. A power play goal off the stick of Riley Donahue put Kamloops ahead at 16:42 and Donahue picked up his second just 9 seconds later, off the ensuing face-off. Delta pulled within a goal at the 18:52 mark, Evan Messenger cutting in to beat Kamloops goaltender Mitch Horsman. After 20 minutes Kamloops had the 3-2 lead and the edge in shots on goal by a margin of 14-10.
Kamloops increased the lead to 2 goals at the 5-minute mark of period 2, Braidy Jorgenson scoring on what appeared to be a crease infraction. Delta replied at 7:08 when Jordan Thauli scoring on a bouncer. They were unable to pick up any momentum from that goal and Kamloops regained their 2-goal led with a goal off the stick of Chris Case at 11:31. That was all the scoring in the middle frame and in fact just one more goal was scored in the game, that going to the Venom's Jamie Forster into the empty net at 19:42. Kamloops' Riley Donahue finished the game with a pair of goals, Jimmy Latin and Braidy Jorgenson each chipped in a goal and 1 assist with Chris Case getting the other goal and Colten Defrias contributing 2 assists. Delta got singles from Ethan Jones, Evan Messenger and Jordan Thauli.
Kamloops picks up gold and is travelling to Ontario to participate in the Founders Cup later in August. Delta grabs silver in a very entertaining and well-played finale to the 2012 Provincial tournament.


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The Ingredients
- 1 roll out pie crust
- 1 (7.5 oz) container chive and onion cream cheese
- Chives, roughly chopped
- ¾ cup parmesan cheese
- 2 tbsp flour
- 1 tsp salt
- 3 eggs
- 3 tomatoes on the vine
- 2 tsp Italian seasoning
The Steps
- Preheat your oven to 400°F.
- Roll out pie crust to fit your Stargazer Cast Iron skillet.
- In a stand mixer, combine cream cheese, eggs, chives, parmesan cheese, flour, and salt. Pour into prepared pie crust.
- Slice tomatoes and add to the top of the tart. Sprinkle with Italian seasoning.
- Bake for 25-30 minutes or until edges begin to brown. Slice and serve warm.
Prep Time: 20min Cook Time: 30min Serves: 4-6


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What the Bible Says About Mediums
The Bible strictly forbids and warns people to not consult with mediums. This includes psychics, astrology, fortune telling, tarot cards, palm readings, seances, and ouija boards.
Isaiah 47:13 – "You are wearied in the multitude of your counsels. Let now the astrologers, the stargazers, and the monthly prognosticators stand up and save you from what shall come upon you."
When we seek guidance from mediums we are trusting in the familiar spirits they are consulting instead of God. God wants us to look to Him alone for guidance, answers and direction.
Exodus 20:5 – "I, the Lord your God, am a jealous God."
Familiar Spirits are Satan's Demons
Familiar spirits are not only God's enemies, but ours as well. In John 10:10 the devil is referred to by Jesus as "the thief."
John 10:10 – "The thief comes only to steal and kill and destroy. I came that they may have life and have it abundantly."
Deceived people think they are benefiting from seeking mediums, but these spirits seek only our harm. This is why God forbids us to consult with them.
Many people are tormented by demonic spirits after consulting with mediums. When we experiment with mediums, we open ourselves up to the demonic and give them permission to come into our life.
Familiar Spirits Know About Us
These spirits are called familiar spirits for a reason. They are assigned to us by the devil to spy on our lives. This is how they seem to know so much about us.
As God assigns His angels to watch over us, the devil also has his fallen angels (demons) watching us. God wants us to have a full and productive life, but the devil seeks our doom, destruction and deception.
1 John 4:1 – "Beloved, do not believe every spirit, but test the spirits, whether they are of God, because many false prophets have gone out into the world."
Mediums are false prophets, frauds and con artists. They take advantage of people for personal gain or for their own self worth (ego). Some are used by familiar spirits (demons) by being deceived into thinking they have a special gift. Others know exactly what they are doing.
Both are being used by demons to give their predictions, whether knowingly or because they are deceived. The source nonetheless is the same – the spirits of darkness! The devil has demonic spirits assigned to us who have a lot of information about our lives. Mediums get their information from these demonic spirits.
Below are a number of scriptures that forbid consulting, seeking or experimenting with mediums or familiar spirits of any sort. These scriptures are self explanatory, take them at face value. God means exactly what He says. Read the entire context to get the full impact of each scripture.
Leviticus 19:31 – "Give no regard to mediums and familiar spirits, do not seek after them, to be defiled by them. I am the Lord your God."
Leviticus 20:6 – "And the person who turns to mediums and familiar spirits, to prostitute himself with them, I will set My face against that person and cut him off from his people."
1 Samuel 28:3 – "Now Samuel had died, and all Israel had lamented for him and buried him in Ramah, in his own city. And Saul had put the mediums and the spiritists out of the land."
1 Samuel 28:9 – "Then the woman said to him, Look, you know what Saul has done, how he has cut off the mediums and the spiritists from the land. Why then do you lay a snare for my life, to cause me to die?"
2 Kings 21:6 – "Also he made his son pass through the fire, practiced soothsaying, used witchcraft, and consulted spiritists and mediums. He did much evil in the sight of the Lord, to provoke Him to anger."
2 Kings 23:24 – "Moreover Josiah put away those who consulted mediums and spiritists, the household gods and idols, all the abominations that were seen in the land of Judah and in Jerusalem, that he might perform the words of the law which were written in the book that Hilkiah the priest found in the house of the Lord."
2 Chronicles 33:6 – "Also he caused his sons to pass through the fire in the Valley of the Son of Hinnom, he practiced soothsaying, used witchcraft and sorcery, and consulted mediums and spiritists. He did much evil in the sight of the Lord, to provoke Him to anger."
Isaiah 8:19 – "And when they say to you, 'Seek those who are mediums and wizards, who whisper and mutter,' should not a people seek their God? Should they seek the dead on behalf of the living?"
Isaiah 19:3 – "The spirit of Egypt will fail in its midst. I will destroy their counsel, And they will consult the idols and the charmers, the mediums and the sorcerers."


text:
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USClaims: Keeping Injured Plaintiffs in Their HomesSeptember 11, 2014
Everyone who works here at USClaims has been asked What do you do? at some point, especially when meeting new people. And let's face it – as important as pre-settlement funding is, it is hard for some people to understand.Read More


text: MrC 121 Posted July 18, 2018 Im selling a mountain bike, its pretty cheap for what it is as I need to make space for a new one.. (Garage full of crap you know the script) Stuck it on Facebook last night. Very descriptive advert and with the words genuine buyers and no offers. Im convinced the Human race is on a very slippery slope. I've have ever bottom feeder and his dog, with either best offer for CASH, swapz for gold chains and can i have more info and pictures.. There are 10 pics and a thorough advert what fucking more do you want.. Its a bicycle! Best one so far is a guy about 10 miles away asking if I can do a video!! Give me strength Quote Share this post Link to post Share on other sites


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Just a short post covering some pitfalls and hoping to helping others to save some valuable time. I recently received a question regarding monitoring Azure Logic Apps and error branching options as covered within this blogpost: Azure Logic App – Conditions: Success and Failure.
The question basically comes down to whatever it's possible to notify users about failed workflow instances. Which is absolutely possible however the interesting part here is where would you like to add the logic?
Monitoring basics – Invalid Template
The first and in my opinion recommended solution when it comes to none functional related issues, is to have a separate monitoring process hosted within a web job or even better Azure Automation workbook. The Azure Logic App API (https://msdn.microsoft.com/en-us/library/azure/dn948513.aspx) allows you to retrieve Runs for a specific workflow and even allows the usage of filters &filter=status eq 'Failed'. This approach also enables the usage of complex conditions / logic.
The second option would include the nonfiction logic within the workflow. This option might be interesting if you are expecting certain exceptions that might require inspection by someone with business / process knowledge and not a technical person in particular.
Now in case you would like to create a fallback exception tree, capturing technical issues, it's important to know that there are some limitations when it comes to retrieving details of the current Run. For example, it's not possible to retrieve details information regarding the current workflow instance within an action at runtime. Simply using the fowling @workflow.xyz expression within an action results in the following exception.
{"code":"InvalidTemplate","message":"Unable to process template language expressions in action 'http0' inputs at line '1' and column '11': 'The template function 'workflow' is not expected at this location.'."}
As mentioned I'm not a big fan of the second option when it comes to technical issues and not being able to use the workflow function within actions makes the implementation even more complex. In the next blog post I will be covering some solution on how build Logic App monitoring dashboard for support staff including alerts / notifications.


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If you need something quick and easy for your next party or gathering, you can't go wrong with spinach artichoke dip. This version is made in the crockpot and goes together in a snap. It's hassle-free and guaranteed leftover-free. Your guests will scarf it up in a flash!
The Author Says: "Although spinach and artichoke dip has become a North American classic, its roots lie in Provençal cuisine, in which the vegetables are usually baked with cheese and served as a gratin. This chunky dip, simplicity itself, always draws rave reviews and disappears to the last drop." –Judith Finlayson
Sumptuous Spinach and Artichoke Dip Recipe
Note: Works best in a small (maximum 3-1/2 quart) slow cooker
1 cup (250 mL) shredded mozzarella cheese
8 ounces (250 g) cream cheese, cubed
1/4 cup (50 mL) grated Parmesan cheese
1 clove garlic, minced
1/4 teaspoon (1 mL) freshly ground black pepper
1 can (14 oz/398 mL) artichokes, drained and finely chopped
1 pound (500 g) fresh spinach, stems removed, or 1 package (10 ounces/300 g) spinach leaves, thawed if frozen (see Tips, below)
Tostadas or tortilla chips
In slow cooker stoneware, combine cheese, cream cheese, Parmesan, garlic, pepper, artichokes, and spinach.
Cover and cook on High for 2 hours, until hot and bubbly. Stir well and serve with tostadas or other tortilla chips.
Yield: 6 to 8 servings
• If you are using fresh spinach leaves in this recipe, take care to wash them thoroughly, as they can be quite gritty. To wash spinach: Fill a clean sink with lukewarm water, Remove the tough stems and submerge the tender leaves in the water, swishing to remove the grit. Rinse thoroughly in a colander under cold running water, checking carefully to ensure that no sand remains. If you are using frozen spinach in this recipe, thaw and squeeze the excess moisture out before adding to the slow cooker.
• If you prefer a smoother dip, place spinach and artichokes in a food processor, in separate batches, and pulse until desired degree of fineness is achieved. Then combine with remaining ingredients in slow cooker stoneware.
You Might Also Like: Pesto, White Bean and Roasted Broccoli Dip Recipe
Recipe Source: "175 Essential Slow Cooker Classics" by Judith Finlayson (Robert Rose)
Reprinted with express permission.